pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1155-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 5,000 3,09E-12 7,435E-09 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 3,106E-09 3,736E-06 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 9,281E-09 7,444E-06 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 2,157E-08 1,298E-05 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 4,297E-08 2,068E-05 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 4,000 4,47E-08 1,793E-05 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 1,279E-07 4,396E-05 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 3,000 2,002E-07 6,021E-05 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of protein kinase cascade GO:0010741 68 30 4,000 3,945E-07 1,055E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 4,392E-07 1,057E-04 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 1,173E-06 2,565E-04 ! endothelial cell migration GO:0043542 28 17 3,000 1,41E-06 2,828E-04 ! inositol metabolic process GO:0006020 28 17 3,000 1,41E-06 2,61E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 3,000 1,41E-06 2,424E-04 ! cardiac muscle tissue development GO:0048738 31 17 3,000 1,41E-06 2,262E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 1,41E-06 2,121E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 2,493E-06 3,528E-04 ! nuclear migration GO:0007097 12 6 2,000 2,493E-06 3,332E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 2,493E-06 3,157E-04 GO:0031272|regulation of pseudopodium assembly, ! response to insulin stimulus GO:0032868 95 46 4,000 3,556E-06 4,278E-04 ! cellular response to hormone stimulus GO:0032870 167 82 5,000 3,821E-06 4,377E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 4,346E-06 4,753E-04 ! macrophage differentiation GO:0030225 11 7 2,000 4,346E-06 4,547E-04 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 5,125E-06 5,137E-04 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 6,928E-06 6,668E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 6,928E-06 6,412E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 6,928E-06 6,174E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 8,551E-06 7,347E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,035E-05 8,59E-04 ! lipid modification GO:0030258 97 57 4,000 1,039E-05 8,331E-04 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 1,339E-05 1,039E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 3,000 1,343E-05 1,009E-03 ! regulation of protein complex assembly GO:0043254 117 61 4,000 1,452E-05 1,059E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 1,452E-05 1,028E-03 ! positive regulation of catabolic process GO:0009896 64 32 3,000 2,009E-05 1,381E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 2,019E-05 1,349E-03 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 2,019E-05 1,313E-03 ! regulation of embryonic development GO:0045995 27 11 2,000 2,019E-05 1,278E-03 ! nucleus localization GO:0051647 19 11 2,000 2,019E-05 1,245E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 2,682E-05 1,613E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 2,682E-05 1,574E-03 ! regulation of hormone metabolic process GO:0032350 26 12 2,000 2,682E-05 1,536E-03 ! negative regulation of cell adhesion GO:0007162 81 35 3,000 2,891E-05 1,617E-03 ! regulation of MAPKKK cascade GO:0043408 142 71 4,000 3,052E-05 1,669E-03 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 3,266E-05 1,746E-03 ! lipid localization GO:0010876 28 13 2,000 3,473E-05 1,817E-03 GO:0019915|lipid storage, ! regulation of monooxygenase activity GO:0032768 33 13 2,000 3,473E-05 1,778E-03 ! regulation of protein stability GO:0031647 73 37 3,000 3,618E-05 1,813E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 4,028E-05 1,978E-03 GO:0042593|glucose homeostasis, ! protein oligomerization GO:0051259 139 78 4,000 4,81E-05 2,315E-03 ! mesenchymal cell development GO:0014031 87 40 3,000 4,948E-05 2,334E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! polyol metabolic process GO:0019751 66 41 3,000 5,461E-05 2,527E-03 ! detection of bacterium GO:0016045 18 15 2,000 5,485E-05 2,49E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 5,485E-05 2,444E-03 ! filopodium assembly GO:0046847 32 16 2,000 6,726E-05 2,942E-03 ! myoblast differentiation GO:0045445 45 17 2,000 8,137E-05 3,496E-03 ! microspike assembly GO:0030035 36 17 2,000 8,137E-05 3,435E-03 ! negative regulation of cell migration GO:0030336 115 46 3,000 8,629E-05 3,58E-03 ! regulation of cell adhesion GO:0030155 212 89 4,000 9,045E-05 3,689E-03 ! regulation of JNK cascade GO:0046328 94 47 3,000 9,395E-05 3,767E-03 ! positive regulation of proteolysis GO:0045862 31 18 2,000 9,728E-05 3,837E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 9,728E-05 3,775E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 9,728E-05 3,715E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 3,000 1,021E-04 3,838E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 1,151E-04 4,26E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 1,349E-04 4,918E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 1,349E-04 4,844E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! pancreas development GO:0031016 35 20 2,000 1,349E-04 4,773E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 1,349E-04 4,704E-03 ! skeletal muscle tissue development GO:0007519 186 99 4,000 1,497E-04 5,145E-03 GO:0060538|skeletal muscle organ development, ! detection of biotic stimulus GO:0009595 29 21 2,000 1,568E-04 5,314E-03 ! negative regulation of cell motion GO:0051271 134 55 3,000 1,741E-04 5,818E-03 ! positive regulation of protein catabolic process GO:0045732 38 22 2,000 1,809E-04 5,962E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 1,809E-04 5,882E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 2,073E-04 6,649E-03 ! sex determination GO:0007530 47 23 2,000 2,073E-04 6,561E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 2,36E-04 7,374E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 2,36E-04 7,279E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 2,36E-04 7,187E-03 ! negative regulation of response to stimulus GO:0048585 100 60 3,000 2,441E-04 7,342E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,505E-04 7,442E-03 ! anagen GO:0042640 6 5 1,000 2,505E-04 7,351E-03 ! microvillus organization GO:0032528 7 5 1,000 2,505E-04 7,263E-03 GO:0030033|microvillus assembly, ! response to food GO:0032094 6 5 1,000 2,505E-04 7,176E-03 ! regulation of glycogen metabolic process GO:0070873 11 5 1,000 2,505E-04 7,092E-03 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,505E-04 7,009E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 2,505E-04 6,929E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 2,505E-04 6,85E-03 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 2,505E-04 6,773E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! enteric nervous system development GO:0048484 8 5 1,000 2,505E-04 6,698E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 2,505E-04 6,624E-03 GO:0051930|regulation of sensory perception of pain, ! cellular anion homeostasis GO:0030002 9 5 1,000 2,505E-04 6,552E-03 GO:0055081|anion homeostasis, ! regulation of insulin secretion GO:0050796 37 25 2,000 2,672E-04 6,912E-03 ! interaction with host GO:0051701 62 25 2,000 2,672E-04 6,839E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 2,672E-04 6,767E-03 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 2,947E-04 7,386E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 3,373E-04 8,366E-03 ! fat cell differentiation GO:0045444 50 27 2,000 3,373E-04 8,281E-03 ! cell projection assembly GO:0030031 120 66 3,000 3,524E-04 8,565E-03 ! regulation of cellular response to stress GO:0080135 128 67 3,000 3,734E-04 8,983E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 3,746E-04 8,923E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! vascular smooth muscle contraction GO:0014829 13 6 1,000 3,746E-04 8,835E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 3,746E-04 8,75E-03 ! male sex determination GO:0030238 15 6 1,000 3,746E-04 8,665E-03 ! hair follicle maturation GO:0048820 7 6 1,000 3,746E-04 8,583E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 3,746E-04 8,502E-03 ! urogenital system development GO:0001655 137 69 3,000 4,178E-04 9,395E-03 ! regulation of peptide secretion GO:0002791 47 29 2,000 4,182E-04 9,317E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 5,227E-04 0,01153674 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,227E-04 0,01143186 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 5,227E-04 0,01132887 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 5,227E-04 0,01122772 ! vesicle fusion GO:0006906 17 7 1,000 5,227E-04 0,01112836 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 1,000 5,227E-04 0,01103074 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 5,227E-04 0,01093482 ! regulation of respiratory burst GO:0060263 11 7 1,000 5,227E-04 0,01084056 ! lymph node development GO:0048535 10 7 1,000 5,227E-04 0,0107479 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 5,227E-04 0,01065682 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 5,227E-04 0,01056726 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 5,227E-04 0,0104792 ! metanephros development GO:0001656 74 32 2,000 5,615E-04 0,01116439 ! BMP signaling pathway GO:0030509 64 32 2,000 5,615E-04 0,01107288 ! steroid biosynthetic process GO:0006694 131 76 3,000 6,034E-04 0,01180251 ! regulation of catabolic process GO:0009894 161 76 3,000 6,034E-04 0,01170733 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 6,724E-04 0,01294233 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 1,000 6,946E-04 0,01326282 ! negative regulation of endocytosis GO:0045806 11 8 1,000 6,946E-04 0,01315839 ! glycine catabolic process GO:0006546 13 8 1,000 6,946E-04 0,01305559 ! ER overload response GO:0006983 12 8 1,000 6,946E-04 0,01295439 ! regulation of fat cell differentiation GO:0045598 15 8 1,000 6,946E-04 0,01285474 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 6,946E-04 0,01275661 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 6,946E-04 0,01265997 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 3,000 6,984E-04 0,01263412 ! regulation of peptidase activity GO:0052547 134 79 3,000 6,984E-04 0,01253984 ! regulation of proteolysis GO:0030162 72 36 2,000 7,964E-04 0,01419348 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 7,964E-04 0,01408912 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 8,635E-04 0,0151643 ! tissue remodeling GO:0048771 76 37 2,000 8,635E-04 0,01505442 ! glycerol ether metabolic process GO:0006662 53 37 2,000 8,635E-04 0,01494611 ! glycogen metabolic process GO:0005977 61 37 2,000 8,635E-04 0,01483935 ! regulation of developmental growth GO:0048638 15 9 1,000 8,9E-04 0,01518766 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 8,9E-04 0,0150807 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 8,9E-04 0,01497524 ! regulation of glycolysis GO:0006110 21 9 1,000 8,9E-04 0,01487125 ! protein heterooligomerization GO:0051291 16 9 1,000 8,9E-04 0,01476869 ! gas homeostasis GO:0033483 16 9 1,000 8,9E-04 0,01466753 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 8,9E-04 0,01456775 ! induction of an organ GO:0001759 14 9 1,000 8,9E-04 0,01446932 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 8,9E-04 0,01437221 GO:0002820|negative regulation of adaptive immune response, ! serine family amino acid catabolic process GO:0009071 16 9 1,000 8,9E-04 0,0142764 ! glucan metabolic process GO:0044042 62 38 2,000 9,34E-04 0,01488262 GO:0006073|cellular glucan metabolic process, ! organic ether metabolic process GO:0018904 55 39 2,000 1,008E-03 0,0159578 ! regulation of hormone secretion GO:0046883 62 40 2,000 1,086E-03 0,01707584 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 1,109E-03 0,01732442 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 1,109E-03 0,01721265 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,109E-03 0,01710231 GO:0005978|glycogen biosynthetic process, ! regulation of insulin receptor signaling pathway GO:0046626 19 10 1,000 1,109E-03 0,01699338 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,109E-03 0,01688583 ! midbrain development GO:0030901 13 10 1,000 1,109E-03 0,01677963 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,109E-03 0,01667475 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of immune effector process GO:0002698 20 10 1,000 1,109E-03 0,01657118 ! localization within membrane GO:0051668 20 10 1,000 1,109E-03 0,01646889 ! ossification GO:0001503 188 90 3,000 1,138E-03 0,01679629 ! bone development GO:0060348 189 91 3,000 1,186E-03 0,0173936 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,252E-03 0,01826302 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,285E-03 0,01862707 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 2,000 1,341E-03 0,01932628 ! energy reserve metabolic process GO:0006112 74 43 2,000 1,341E-03 0,01921124 ! thyroid gland development GO:0030878 26 11 1,000 1,351E-03 0,01923105 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,351E-03 0,01911792 ! negative regulation of ossification GO:0030279 26 11 1,000 1,351E-03 0,01900612 ! vasoconstriction GO:0042310 18 11 1,000 1,351E-03 0,01889562 ! neuroblast proliferation GO:0007405 24 11 1,000 1,351E-03 0,0187864 ! negative regulation of glucose import GO:0046325 17 11 1,000 1,351E-03 0,01867843 GO:0010829|negative regulation of glucose transport, ! developmental induction GO:0031128 19 11 1,000 1,351E-03 0,0185717 GO:0045168|cell-cell signaling involved in cell fate specification, ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 1,39E-03 0,01900771 ! leukocyte differentiation GO:0002521 202 96 3,000 1,445E-03 0,01964555 ! cell growth GO:0016049 84 45 2,000 1,531E-03 0,02069556 ! interphase GO:0051325 213 98 3,000 1,559E-03 0,02096019 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 1,000 1,616E-03 0,02159529 ! virus-host interaction GO:0019048 29 12 1,000 1,616E-03 0,02147597 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,616E-03 0,02135797 ! entry into host cell GO:0030260 32 12 1,000 1,616E-03 0,02124126 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 1,616E-03 0,02112582 ! autonomic nervous system development GO:0048483 24 12 1,000 1,616E-03 0,02101163 ! gland morphogenesis GO:0022612 29 12 1,000 1,616E-03 0,02089866 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,616E-03 0,02078691 ! T cell homeostasis GO:0043029 25 12 1,000 1,616E-03 0,02067634 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,632E-03 0,02077426 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,632E-03 0,02066492 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,632E-03 0,02055673 ! protein homooligomerization GO:0051260 76 47 2,000 1,737E-03 0,02176369 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,846E-03 0,02300947 ! organelle fusion GO:0048284 32 13 1,000 1,903E-03 0,02360161 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,903E-03 0,02348057 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,903E-03 0,02336077 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 1,903E-03 0,02324219 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 1,903E-03 0,02312481 ! regulation of cell projection organization GO:0031344 121 50 2,000 2,076E-03 0,02510299 ! regulation of ossification GO:0030278 117 50 2,000 2,076E-03 0,02497747 ! chromatin remodeling GO:0006338 109 51 2,000 2,198E-03 0,02630959 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,213E-03 0,02635727 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 2,213E-03 0,02622743 ! regulation of RNA stability GO:0043487 32 14 1,000 2,213E-03 0,02609887 ! positive regulation of growth GO:0045927 90 52 2,000 2,324E-03 0,02727511 ! regulation of protein polymerization GO:0032271 103 53 2,000 2,454E-03 0,02866569 ! response to UV GO:0009411 104 53 2,000 2,454E-03 0,02852721 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 2,545E-03 0,02943735 ! sulfate transport GO:0008272 23 15 1,000 2,545E-03 0,0292965 ! regulation of vasodilation GO:0042312 26 15 1,000 2,545E-03 0,02915699 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 2,545E-03 0,02901881 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,545E-03 0,02888193 ! lymphocyte homeostasis GO:0002260 30 15 1,000 2,545E-03 0,02874633 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 2,729E-03 0,03067657 ! regulation of protein catabolic process GO:0042176 116 55 2,000 2,729E-03 0,03053389 ! skeletal muscle fiber development GO:0048741 111 56 2,000 2,872E-03 0,0319951 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,899E-03 0,03214083 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 2,899E-03 0,0319934 ! bone remodeling GO:0046849 27 16 1,000 2,899E-03 0,03184731 ! startle response GO:0001964 28 16 1,000 2,899E-03 0,03170255 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 2,899E-03 0,0315591 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 2,899E-03 0,03141694 ! negative regulation of immune response GO:0050777 35 16 1,000 2,899E-03 0,03127606 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,899E-03 0,03113643 ! negative regulation of inflammatory response GO:0050728 22 16 1,000 2,899E-03 0,03099805 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 2,899E-03 0,03086089 ! regulation of bone remodeling GO:0046850 137 57 2,000 3,021E-03 0,03201824 ! muscle fiber development GO:0048747 112 57 2,000 3,021E-03 0,03187781 ! positive regulation of cell migration GO:0030335 126 57 2,000 3,021E-03 0,0317386 ! regulation of intracellular transport GO:0032386 101 57 2,000 3,021E-03 0,03160061 ! regulation of tissue remodeling GO:0034103 140 58 2,000 3,174E-03 0,03305841 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 3,274E-03 0,03395862 ! signal complex assembly GO:0007172 41 17 1,000 3,274E-03 0,03381287 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,274E-03 0,03366837 ! glycine metabolic process GO:0006544 28 17 1,000 3,274E-03 0,0335251 ! neural crest cell migration GO:0001755 37 17 1,000 3,274E-03 0,03338305 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 3,274E-03 0,03324219 ! positive regulation of secretion GO:0051047 95 59 2,000 3,332E-03 0,03368112 ! establishment of organelle localization GO:0051656 109 59 2,000 3,332E-03 0,0335402 ! kidney development GO:0001822 122 60 2,000 3,494E-03 0,03502957 ! mesoderm development GO:0007498 119 61 2,000 3,661E-03 0,0365542 ! neuron maturation GO:0042551 42 18 1,000 3,672E-03 0,03650389 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 3,672E-03 0,03635367 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 3,672E-03 0,03620468 ! viral reproductive process GO:0022415 126 62 2,000 3,834E-03 0,03764737 ! detection of external stimulus GO:0009581 91 63 2,000 4,011E-03 0,03922493 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 4,011E-03 0,03906612 ! negative regulation of defense response GO:0031348 25 19 1,000 4,09E-03 0,03968004 ! lipid phosphorylation GO:0046834 35 19 1,000 4,09E-03 0,03952069 ! G1 phase GO:0051318 40 19 1,000 4,09E-03 0,0393626 ! positive regulation of cell motion GO:0051272 146 64 2,000 4,192E-03 0,0401866 ! myeloid cell differentiation GO:0030099 111 65 2,000 4,379E-03 0,04181038 ! protein amino acid acetylation GO:0006473 39 20 1,000 4,53E-03 0,04307507 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 4,53E-03 0,04290548 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 4,53E-03 0,04273722 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 4,53E-03 0,04257028 ! regulation of glucose import GO:0046324 29 20 1,000 4,53E-03 0,04240464 GO:0010827|regulation of glucose transport, ! developmental maturation GO:0021700 116 66 2,000 4,571E-03 0,04262621 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 4,768E-03 0,04428944 ! activation of MAPK activity GO:0000187 115 67 2,000 4,768E-03 0,04411909 ! lung development GO:0030324 144 67 2,000 4,768E-03 0,04395006 ! homeostasis of number of cells GO:0048872 114 67 2,000 4,768E-03 0,04378231 ! negative regulation of kinase activity GO:0033673 131 68 2,000 4,969E-03 0,04546203 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 4,969E-03 0,04528983 ! viral reproduction GO:0016032 134 68 2,000 4,969E-03 0,04511892 ! regulation of cell killing GO:0031341 42 21 1,000 4,99E-03 0,04513322 ! inactivation of MAPK activity GO:0000188 39 21 1,000 4,99E-03 0,04496418 ! smooth muscle contraction GO:0006939 46 21 1,000 4,99E-03 0,0447964 ! regulation of vasoconstriction GO:0019229 39 21 1,000 4,99E-03 0,04462987 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 4,99E-03 0,04446458 ! gut development GO:0048565 39 21 1,000 4,99E-03 0,0443005 ! negative regulation of cell size GO:0045792 134 69 2,000 5,176E-03 0,04578786 ! respiratory tube development GO:0030323 150 70 2,000 5,388E-03 0,04748864 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 5,471E-03 0,04803816 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 5,471E-03 0,04786348 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 5,471E-03 0,04769006 ! ureteric bud development GO:0001657 43 22 1,000 5,471E-03 0,04751789 ! activation of JUN kinase activity GO:0007257 42 22 1,000 5,471E-03 0,04734696 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 5,471E-03 0,04717726 ! regulation of caspase activity GO:0043281 122 72 2,000 5,828E-03 0,05007813 ! negative regulation of transferase activity GO:0051348 140 72 2,000 5,828E-03 0,04989992 ! respiratory system development GO:0060541 153 72 2,000 5,828E-03 0,04972297 ! positive regulation of DNA replication GO:0045740 43 23 1,000 5,972E-03 0,0507722 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 5,972E-03 0,05059342 ! protein amino acid O-linked glycosylation GO:0006493 42 23 1,000 5,972E-03 0,0504159 ! regulation of DNA recombination GO:0000018 48 23 1,000 5,972E-03 0,05023962 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 5,972E-03 0,05006457 ! barbed-end actin filament capping GO:0051016 50 23 1,000 5,972E-03 0,04989073 GO:0051693|actin filament capping, ! regulation of bone mineralization GO:0030500 49 23 1,000 5,972E-03 0,0497181 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 6,288E-03 0,05217096 ! organelle localization GO:0051640 136 74 2,000 6,288E-03 0,05199167 ! vesicle docking GO:0048278 47 24 1,000 6,493E-03 0,05350391 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 6,493E-03 0,05332131 ! membrane depolarization GO:0051899 39 24 1,000 6,493E-03 0,05313994 ! leukocyte homeostasis GO:0001776 44 24 1,000 6,493E-03 0,05295981 ! protein tetramerization GO:0051262 52 24 1,000 6,493E-03 0,05278089 ! vasculogenesis GO:0001570 46 25 1,000 7,035E-03 0,05698915 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 7,035E-03 0,05679791 ! osteoblast differentiation GO:0001649 60 25 1,000 7,035E-03 0,05660795 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 7,035E-03 0,05641926 ! neural crest cell development GO:0014032 54 25 1,000 7,035E-03 0,05623182 GO:0014033|neural crest cell differentiation, ! regulation of biomineral formation GO:0070167 51 25 1,000 7,035E-03 0,05604562 ! somitogenesis GO:0001756 43 25 1,000 7,035E-03 0,05586065 ! regulation of blood coagulation GO:0030193 40 25 1,000 7,035E-03 0,0556769 ! embryonic pattern specification GO:0009880 44 26 1,000 7,596E-03 0,05992107 ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 7,596E-03 0,05972525 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 7,596E-03 0,0595307 ! initiation of viral infection GO:0019059 57 26 1,000 7,596E-03 0,05933742 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 7,596E-03 0,05914539 ! molting cycle process GO:0022404 50 26 1,000 7,596E-03 0,0589546 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 7,596E-03 0,05876503 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 7,596E-03 0,05857668 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 7,596E-03 0,05838954 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 7,596E-03 0,05820358 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 7,596E-03 0,05801881 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 7,596E-03 0,05783521 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 7,596E-03 0,05765276 ! muscle cell differentiation GO:0042692 159 80 2,000 7,797E-03 0,05899306 ! protein import into nucleus GO:0006606 158 80 2,000 7,797E-03 0,05880813 ! inorganic anion transport GO:0015698 138 80 2,000 7,797E-03 0,05862435 ! response to hypoxia GO:0001666 171 81 2,000 8,067E-03 0,06046827 ! nuclear import GO:0051170 161 81 2,000 8,067E-03 0,06028048 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 8,177E-03 0,06090737 ! protein amino acid acylation GO:0043543 55 27 1,000 8,177E-03 0,06071938 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 8,177E-03 0,06053255 ! response to oxygen levels GO:0070482 176 83 2,000 8,625E-03 0,06365306 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 8,777E-03 0,06457718 ! negative regulation of protein modification process GO:0031400 60 28 1,000 8,777E-03 0,0643803 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 8,777E-03 0,06418461 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 8,777E-03 0,06399011 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 8,777E-03 0,06379679 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 8,777E-03 0,06360463 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 8,777E-03 0,06341362 ! negative regulation of transport GO:0051051 153 84 2,000 8,912E-03 0,06419482 ! respiratory gaseous exchange GO:0007585 57 29 1,000 9,396E-03 0,06748179 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 9,396E-03 0,06728095 ! regulation of coagulation GO:0050818 46 29 1,000 9,396E-03 0,0670813 ! protein localization in nucleus GO:0034504 176 87 2,000 9,805E-03 0,06979806 ! regulation of protein transport GO:0051223 154 87 2,000 9,805E-03 0,06959217 GO:0070201|regulation of establishment of protein localization, ! membrane docking GO:0022406 61 30 1,000 0,0100339 0,07100463 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,0100339 0,0707964 ! response to heat GO:0009408 50 30 1,000 0,0100339 0,0705894 ! gland development GO:0048732 206 88 2,000 0,01011451 0,07094904 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01069068 0,07477258 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01069068 0,07455584 ! triglyceride metabolic process GO:0006641 43 31 1,000 0,01069068 0,07434036 ! mesoderm formation GO:0001707 69 31 1,000 0,01069068 0,07412613 ! serine family amino acid metabolic process GO:0009069 49 31 1,000 0,01069068 0,07391312 ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 0,01136596 0,07835671 ! cholesterol transport GO:0030301 56 32 1,000 0,01136596 0,07813283 ! spindle organization GO:0007051 46 32 1,000 0,01136596 0,07791023 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01136596 0,0776889 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 0,01136596 0,07746881 ! hindbrain development GO:0030902 61 32 1,000 0,01136596 0,07724998 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01136596 0,07703237 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,01174484 0,07937662 ! formation of primary germ layer GO:0001704 72 33 1,000 0,01205954 0,08127525 ! cell fate specification GO:0001708 52 33 1,000 0,01205954 0,08104823 ! sterol transport GO:0015918 57 33 1,000 0,01205954 0,08082246 ! adult locomotory behavior GO:0008344 59 33 1,000 0,01205954 0,08059796 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,01277124 0,08511802 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,01277124 0,08488289 ! placenta development GO:0001890 53 34 1,000 0,01277124 0,08464905 ! detection of stimulus GO:0051606 151 96 2,000 0,01279135 0,08454941 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,01315166 0,08669287 ! regulation of protein localization GO:0032880 176 97 2,000 0,01315166 0,086456 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,01350085 0,08850965 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01350085 0,08826913 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01350085 0,08802992 ! cell cycle arrest GO:0007050 213 100 2,000 0,0142672 0,09277538 ! actomyosin structure organization GO:0031032 62 37 1,000 0,01501301 0,097362 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01579517 0,10215911 ! lipid homeostasis GO:0055088 67 38 1,000 0,01579517 0,10188523 ! nucleotide catabolic process GO:0009166 61 38 1,000 0,01579517 0,10161281 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,01579517 0,10134184 ! mammary gland development GO:0030879 86 39 1,000 0,01659447 0,10618698 ! segmentation GO:0035282 67 39 1,000 0,01659447 0,10590532 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,01659447 0,10562514 ! cytokinesis GO:0000910 72 40 1,000 0,01741072 0,11052819 ! hormone-mediated signaling GO:0009755 74 41 1,000 0,01824371 0,11551151 ! T cell differentiation GO:0030217 81 41 1,000 0,01824371 0,11520833 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,01824371 0,11490674 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,01824371 0,11460672 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01909328 0,11963131 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01909328 0,11932058 ! regulation of tube size GO:0035150 71 42 1,000 0,01909328 0,11901145 GO:0050880|regulation of blood vessel size, ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,01909328 0,11870393 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,01995922 0,12376774 ! glucose transport GO:0015758 65 43 1,000 0,01995922 0,12344957 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,01995922 0,12313303 ! hexose transport GO:0008645 67 44 1,000 0,02084136 0,12824631 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 1,000 0,02084136 0,12791916 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,02084136 0,12759366 ! developmental growth GO:0048589 82 44 1,000 0,02084136 0,12726982 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,02173951 0,13241839 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,02173951 0,132084 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,02173951 0,13175129 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,02265349 0,13694549 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,02265349 0,13660227 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02358313 0,1418525 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,02358313 0,14149876 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,02358313 0,14114677 ! JNK cascade GO:0007254 91 47 1,000 0,02358313 0,14079653 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,02452823 0,14607654 ! activation of caspase activity GO:0006919 84 48 1,000 0,02452823 0,14571586 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,02452823 0,14535695 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,02452823 0,14499981 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02498312 0,14732694 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02498312 0,14696672 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02498312 0,14660827 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02498312 0,14625156 ! neuron fate determination GO:0048664 7 5 0,000 0,02498312 0,14589658 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02498312 0,14554332 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02498312 0,14519176 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02498312 0,1448419 ! polyol transport GO:0015791 12 5 0,000 0,02498312 0,14449373 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02498312 0,14414722 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02498312 0,14380237 ! response to superoxide GO:0000303 10 5 0,000 0,02498312 0,14345917 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02498312 0,1431176 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02498312 0,14277765 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02498312 0,14243931 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02498312 0,14210258 ! female meiosis GO:0007143 7 5 0,000 0,02498312 0,14176743 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02498312 0,14143386 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02498312 0,14110185 ! cobalt ion transport GO:0006824 11 5 0,000 0,02498312 0,14077141 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02498312 0,1404425 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02498312 0,14011513 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02498312 0,13978928 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02498312 0,13946494 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02498312 0,13914211 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02498312 0,13882076 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02498312 0,1385009 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02498312 0,13818251 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02498312 0,13786557 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02498312 0,13755009 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02498312 0,13723605 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02498312 0,13692344 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02498312 0,13661225 ! negative chemotaxis GO:0050919 14 5 0,000 0,02498312 0,13630247 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02498312 0,1359941 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02498312 0,13568711 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02498312 0,13538151 ! behavioral response to pain GO:0048266 9 5 0,000 0,02498312 0,13507728 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02498312 0,13477442 ! Notch receptor processing GO:0007220 8 5 0,000 0,02498312 0,13447291 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02498312 0,13417275 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02498312 0,13387392 ! micturition GO:0060073 9 5 0,000 0,02498312 0,13357642 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02498312 0,13328024 ! copulation GO:0007620 9 5 0,000 0,02498312 0,13298538 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02498312 0,13269181 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02498312 0,13239954 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02498312 0,13210855 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02498312 0,13181884 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02498312 0,13153039 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02498312 0,13124321 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02498312 0,13095728 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02498312 0,13067259 ! grooming behavior GO:0007625 6 5 0,000 0,02498312 0,13038913 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02498312 0,13010691 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02498312 0,1298259 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02498312 0,1295461 ! response to protozoan GO:0001562 10 5 0,000 0,02498312 0,12926751 ! lymph vessel development GO:0001945 10 5 0,000 0,02498312 0,12899011 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02498312 0,1287139 ! endochondral ossification GO:0001958 16 5 0,000 0,02498312 0,12843887 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02498312 0,12816501 ! parathyroid gland development GO:0060017 13 5 0,000 0,02498312 0,12789232 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02498312 0,12762079 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02498312 0,1273504 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02498312 0,12708116 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02498312 0,12681306 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02498312 0,12654608 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02498312 0,12628023 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02498312 0,12601549 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02498312 0,12575186 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02498312 0,12548933 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02498312 0,1252279 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02498312 0,12496755 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02498312 0,12470828 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02498312 0,12445008 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02498312 0,12419295 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02498312 0,12393689 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02498312 0,12368187 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02498312 0,12342791 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02498312 0,12317498 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02498312 0,12292309 ! histidine catabolic process GO:0006548 6 5 0,000 0,02498312 0,12267222 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02498312 0,12242238 ! valine metabolic process GO:0006573 10 5 0,000 0,02498312 0,12217356 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02498312 0,12192574 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02498312 0,12167893 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02498312 0,12143311 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02498312 0,12118829 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02498312 0,12094445 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02498312 0,12070159 ! polyol catabolic process GO:0046174 7 5 0,000 0,02498312 0,1204597 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02498312 0,12021878 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02498312 0,11997882 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02498312 0,11973982 ! muscle cell migration GO:0014812 8 5 0,000 0,02498312 0,11950177 ! mitochondrial fission GO:0000266 8 5 0,000 0,02498312 0,11926466 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02498312 0,1190285 ! mRNA transcription GO:0009299 9 5 0,000 0,02498312 0,11879326 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02498312 0,11855896 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02498312 0,11832557 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02498312 0,1180931 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02498312 0,11786155 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02498312 0,1176309 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02498312 0,11740115 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02498312 0,1171723 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02498312 0,11694434 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02498312 0,11671726 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02498312 0,11649107 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02498312 0,11626575 ! forebrain neuron development GO:0021884 13 5 0,000 0,02498312 0,11604129 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02498312 0,11581771 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02498312 0,11559498 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02498312 0,11537311 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02498312 0,11515209 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02498312 0,11493191 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02498312 0,11471258 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02498312 0,11449408 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02498312 0,11427641 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02498312 0,11405956 ! basic amino acid transport GO:0015802 11 5 0,000 0,02498312 0,11384354 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02498312 0,11362834 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02498312 0,11341394 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02498312 0,11320036 ! depyrimidination GO:0045008 10 5 0,000 0,02498312 0,11298758 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02498312 0,11277559 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02498312 0,1125644 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02498312 0,112354 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02498312 0,11214438 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02498312 0,11193555 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02498312 0,11172749 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02498312 0,1115202 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02498312 0,11131369 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02498312 0,11110793 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02498312 0,11090293 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02498312 0,11069869 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02498312 0,1104952 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02498312 0,11029246 ! response to arsenic GO:0046685 10 5 0,000 0,02498312 0,11009046 ! mast cell degranulation GO:0043303 7 5 0,000 0,02498312 0,1098892 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02498312 0,10968867 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02498312 0,10948887 ! response to cadmium ion GO:0046686 7 5 0,000 0,02498312 0,1092898 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02498312 0,10909145 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02498312 0,10889382 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02498312 0,10869691 ! decidualization GO:0046697 11 5 0,000 0,02498312 0,1085007 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02498312 0,10830521 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02498312 0,10811041 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02498312 0,10791632 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02498312 0,10772292 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02498312 0,10753022 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02498312 0,1073382 ! neural tube patterning GO:0021532 7 5 0,000 0,02498312 0,10714686 ! embryonic cleavage GO:0040016 6 5 0,000 0,02498312 0,10695621 ! peroxisome fission GO:0016559 5 5 0,000 0,02498312 0,10676623 ! histone demethylation GO:0016577 10 5 0,000 0,02498312 0,10657693 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02498312 0,1063883 ! mitotic recombination GO:0006312 9 5 0,000 0,02498312 0,10620034 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02498312 0,10601303 ! metaphase plate congression GO:0051310 7 5 0,000 0,02498312 0,10582639 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02498312 0,1056404 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02498312 0,10545507 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02498312 0,10527039 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02498312 0,10508635 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02498312 0,10490295 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02498312 0,10472019 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02498312 0,10453807 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02498312 0,10435658 ! plasminogen activation GO:0031639 5 5 0,000 0,02498312 0,10417572 ! B cell homeostasis GO:0001782 13 5 0,000 0,02498312 0,10399548 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02498312 0,10381587 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02498312 0,10363688 ! metaphase GO:0051323 8 5 0,000 0,02498312 0,1034585 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02498312 0,10328074 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02498312 0,10310359 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02498312 0,10292704 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02498312 0,10275109 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02498312 0,10257575 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02498312 0,10240101 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02498312 0,10222685 ! response to redox state GO:0051775 5 5 0,000 0,02498312 0,10205329 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02498312 0,10188032 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02498312 0,10170794 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02498312 0,10153613 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02498312 0,10136491 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02498312 0,10119426 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02498312 0,10102419 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02498312 0,10085468 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02498312 0,10068575 ! striatum development GO:0021756 9 5 0,000 0,02498312 0,10051737 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02498312 0,10034957 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02498312 0,10018232 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02498312 0,10001562 ! glial cell migration GO:0008347 11 5 0,000 0,02498312 0,09984949 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02498312 0,0996839 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02498312 0,09951886 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02498312 0,09935436 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02498312 0,09919041 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02498312 0,099027 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02498312 0,09886413 ! neuroprotection GO:0043526 6 5 0,000 0,02498312 0,09870179 ! neural plate development GO:0001840 8 5 0,000 0,02498312 0,09853998 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02498312 0,09837871 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02498312 0,09821796 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02498312 0,09805773 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02498312 0,09789803 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02498312 0,09773885 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02498312 0,09758018 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02498312 0,09742203 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02498312 0,09726439 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02498312 0,09710725 ! spindle assembly GO:0051225 6 5 0,000 0,02498312 0,09695063 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02498312 0,09679451 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02498312 0,09663889 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02498312 0,09648377 ! drug metabolic process GO:0017144 6 5 0,000 0,02498312 0,09632915 ! stem cell division GO:0017145 11 5 0,000 0,02498312 0,09617502 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02498312 0,09602139 ! organ regeneration GO:0031100 7 5 0,000 0,02498312 0,09586825 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02498312 0,09571559 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02498312 0,09556342 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,02548863 0,09734228 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,02548863 0,09718802 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,02548863 0,09703424 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02548863 0,09688095 ! endocrine system development GO:0035270 104 49 1,000 0,02548863 0,09672814 ! neuromuscular process GO:0050905 99 50 1,000 0,02646414 0,10027201 ! histone modification GO:0016570 91 50 1,000 0,02646414 0,10011435 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,02646414 0,09995719 ! positive regulation of binding GO:0051099 78 51 1,000 0,0274546 0,10353569 ! viral infectious cycle GO:0019058 99 51 1,000 0,0274546 0,10337366 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,0274546 0,10321214 ! vesicle organization GO:0016050 107 51 1,000 0,0274546 0,10305112 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,0274546 0,10289061 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,02845983 0,10649198 ! membrane fusion GO:0006944 110 52 1,000 0,02845983 0,10632662 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02845983 0,10616177 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,02947965 0,10979573 ! cell maturation GO:0048469 100 53 1,000 0,02947965 0,10962603 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02990483 0,11103554 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02990483 0,11086445 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02990483 0,11069389 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02990483 0,11052385 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02990483 0,11035434 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02990483 0,11018534 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02990483 0,11001686 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02990483 0,1098489 ! sleep GO:0030431 13 6 0,000 0,02990483 0,10968144 ! response to oxygen radical GO:0000305 11 6 0,000 0,02990483 0,1095145 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02990483 0,10934807 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02990483 0,10918214 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02990483 0,10901671 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02990483 0,10885178 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02990483 0,10868735 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02990483 0,10852342 ! forebrain regionalization GO:0021871 8 6 0,000 0,02990483 0,10835998 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02990483 0,10819703 ! male meiosis GO:0007140 7 6 0,000 0,02990483 0,10803458 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02990483 0,1078726 ! response to zinc ion GO:0010043 9 6 0,000 0,02990483 0,10771112 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02990483 0,10755012 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02990483 0,10738959 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02990483 0,10722955 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02990483 0,10706998 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02990483 0,10691089 ! malate metabolic process GO:0006108 11 6 0,000 0,02990483 0,10675227 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02990483 0,10659411 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02990483 0,10643643 ! protein refolding GO:0042026 15 6 0,000 0,02990483 0,10627921 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02990483 0,10612246 ! opsonization GO:0008228 8 6 0,000 0,02990483 0,10596617 ! mating behavior GO:0007617 7 6 0,000 0,02990483 0,10581033 ! neuron remodeling GO:0016322 15 6 0,000 0,02990483 0,10565496 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02990483 0,10550004 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02990483 0,10534557 ! equilibrioception GO:0050957 14 6 0,000 0,02990483 0,10519156 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02990483 0,105038 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02990483 0,10488488 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02990483 0,10473221 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02990483 0,10457998 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02990483 0,1044282 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02990483 0,10427685 ! toxin metabolic process GO:0009404 11 6 0,000 0,02990483 0,10412594 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02990483 0,10397547 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02990483 0,10382544 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02990483 0,10367583 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02990483 0,10352666 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02990483 0,10337791 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02990483 0,10322959 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02990483 0,1030817 ! thymic T cell selection GO:0045061 12 6 0,000 0,02990483 0,10293423 ! protein lipoylation GO:0009249 10 6 0,000 0,02990483 0,10278718 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02990483 0,10264055 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02990483 0,10249434 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02990483 0,10234855 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02990483 0,10220316 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02990483 0,10205819 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,02990483 0,10191364 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02990483 0,10176949 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02990483 0,10162574 ! hyperosmotic response GO:0006972 9 6 0,000 0,02990483 0,10148241 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02990483 0,10133947 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02990483 0,10119694 ! urea metabolic process GO:0019627 7 6 0,000 0,02990483 0,10105481 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02990483 0,10091308 ! neutrophil activation GO:0042119 8 6 0,000 0,02990483 0,10077175 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02990483 0,10063081 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02990483 0,10049026 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02990483 0,10035011 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02990483 0,10021034 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02990483 0,10007097 ! neuron apoptosis GO:0051402 9 6 0,000 0,02990483 0,09993198 ! nucleoside salvage GO:0043174 9 6 0,000 0,02990483 0,09979338 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02990483 0,09965516 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02990483 0,09951733 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02990483 0,09937987 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02990483 0,0992428 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02990483 0,0991061 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02990483 0,09896978 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02990483 0,09883383 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02990483 0,09869825 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02990483 0,09856305 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02990483 0,09842822 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02990483 0,09829375 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02990483 0,09815966 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02990483 0,09802592 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02990483 0,09789255 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02990483 0,09775955 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02990483 0,0976269 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02990483 0,09749462 ! neural nucleus development GO:0048857 14 6 0,000 0,02990483 0,09736269 ! response to UV-C GO:0010225 11 6 0,000 0,02990483 0,09723112 ! astrocyte development GO:0014002 15 6 0,000 0,02990483 0,0970999 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02990483 0,09696904 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02990483 0,09683853 ! interaction with symbiont GO:0051702 13 6 0,000 0,02990483 0,09670837 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02990483 0,09657856 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02990483 0,0964491 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02990483 0,09631998 ! response to copper ion GO:0046688 10 6 0,000 0,02990483 0,09619121 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02990483 0,09606279 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02990483 0,0959347 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02990483 0,09580696 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02990483 0,09567956 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02990483 0,09555249 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02990483 0,09542577 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02990483 0,09529937 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02990483 0,09517332 ! Schwann cell development GO:0014044 15 6 0,000 0,02990483 0,09504759 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02990483 0,0949222 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02990483 0,09479714 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02990483 0,0946724 ! subpallium development GO:0021544 10 6 0,000 0,02990483 0,094548 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02990483 0,09442392 ! histone ubiquitination GO:0016574 8 6 0,000 0,02990483 0,09430017 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02990483 0,09417674 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02990483 0,09405363 ! G2 phase GO:0051319 16 6 0,000 0,02990483 0,09393084 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02990483 0,09380838 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02990483 0,09368623 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02990483 0,0935644 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02990483 0,09344289 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02990483 0,0933217 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02990483 0,09320081 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02990483 0,09308024 ! receptor internalization GO:0031623 10 6 0,000 0,02990483 0,09295998 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02990483 0,09284004 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02990483 0,0927204 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02990483 0,09260106 ! protein deubiquitination GO:0016579 14 6 0,000 0,02990483 0,09248204 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02990483 0,09236332 ! protein destabilization GO:0031648 9 6 0,000 0,02990483 0,09224491 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02990483 0,0921268 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02990483 0,09200899 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02990483 0,09189148 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02990483 0,09177427 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02990483 0,09165736 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02990483 0,09154075 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02990483 0,09142443 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02990483 0,09130841 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02990483 0,09119268 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02990483 0,09107725 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02990483 0,09096211 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02990483 0,09084726 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02990483 0,0907327 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02990483 0,09061842 ! catecholamine transport GO:0051937 9 6 0,000 0,02990483 0,09050444 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02990483 0,09039074 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02990483 0,09027732 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02990483 0,09016419 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02990483 0,09005135 ! maternal placenta development GO:0001893 12 6 0,000 0,02990483 0,08993878 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02990483 0,0898265 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02990483 0,0897145 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02990483 0,08960277 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02990483 0,08949133 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02990483 0,08938016 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02990483 0,08926926 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,0305139 0,09097453 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,0305139 0,09086193 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,0315624 0,09386792 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,0315624 0,09375203 ! gastrulation GO:0007369 112 55 1,000 0,0315624 0,09363643 ! heart morphogenesis GO:0003007 97 55 1,000 0,0315624 0,09352112 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,0315624 0,09340608 ! regulation of actin filament length GO:0030832 105 56 1,000 0,032625 0,09643212 ! regulation of DNA replication GO:0006275 101 56 1,000 0,032625 0,0963138 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,032625 0,09619577 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,03370151 0,09924827 ! maintenance of location GO:0051235 118 57 1,000 0,03370151 0,09912694 ! regulation of endocytosis GO:0030100 91 58 1,000 0,03479178 0,10220883 ! adult behavior GO:0030534 99 58 1,000 0,03479178 0,10208418 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,03479178 0,10195984 ! tRNA transcription GO:0009304 14 7 0,000 0,03480186 0,10186531 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03480186 0,10174153 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03480186 0,10161806 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03480186 0,10149489 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03480186 0,10137201 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03480186 0,10124943 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03480186 0,10112715 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03480186 0,10100516 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03480186 0,10088347 ! prostate gland development GO:0030850 13 7 0,000 0,03480186 0,10076207 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03480186 0,10064096 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03480186 0,10052015 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03480186 0,10039962 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03480186 0,10027938 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03480186 0,10015943 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03480186 0,10003976 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03480186 0,09992038 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03480186 0,09980129 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03480186 0,09968248 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03480186 0,09956395 ! glycolipid transport GO:0046836 10 7 0,000 0,03480186 0,0994457 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03480186 0,09932774 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03480186 0,09921005 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03480186 0,09909264 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03480186 0,09897551 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03480186 0,09885866 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03480186 0,09874208 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03480186 0,09862577 ! mRNA stabilization GO:0048255 18 7 0,000 0,03480186 0,09850974 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03480186 0,09839398 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03480186 0,0982785 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03480186 0,09816328 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03480186 0,09804834 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03480186 0,09793366 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03480186 0,09781925 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03480186 0,09770511 ! lipoprotein transport GO:0042953 14 7 0,000 0,03480186 0,09759124 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03480186 0,09747763 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03480186 0,09736428 ! rhythmic behavior GO:0007622 15 7 0,000 0,03480186 0,0972512 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03480186 0,09713838 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03480186 0,09702582 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03480186 0,09691352 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03480186 0,09680148 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03480186 0,0966897 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03480186 0,09657818 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03480186 0,09646691 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03480186 0,0963559 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03480186 0,09624515 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03480186 0,09613465 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03480186 0,0960244 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03480186 0,09591441 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03480186 0,09580467 ! spinal cord patterning GO:0021511 13 7 0,000 0,03480186 0,09569518 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03480186 0,09558594 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03480186 0,09547695 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03480186 0,0953682 ! adrenal gland development GO:0030325 17 7 0,000 0,03480186 0,09525971 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03480186 0,09515146 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03480186 0,09504345 ! ovulation GO:0030728 9 7 0,000 0,03480186 0,09493569 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03480186 0,09482818 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03480186 0,09472091 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03480186 0,09461388 ! microtubule nucleation GO:0007020 20 7 0,000 0,03480186 0,09450709 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03480186 0,09440054 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03480186 0,09429424 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03480186 0,09418817 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03480186 0,09408234 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03480186 0,09397675 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03480186 0,09387139 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03480186 0,09376627 ! galactose metabolic process GO:0006012 13 7 0,000 0,03480186 0,09366139 ! response to dietary excess GO:0002021 8 7 0,000 0,03480186 0,09355674 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03480186 0,09345232 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03480186 0,09334814 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03480186 0,09324419 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03480186 0,09314047 ! organ growth GO:0035265 15 7 0,000 0,03480186 0,09303698 ! purine salvage GO:0043101 10 7 0,000 0,03480186 0,09293372 ! nucleoside transport GO:0015858 8 7 0,000 0,03480186 0,09283069 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03480186 0,09272789 ! parturition GO:0007567 14 7 0,000 0,03480186 0,09262531 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03480186 0,09252296 ! rRNA modification GO:0000154 14 7 0,000 0,03480186 0,09242084 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03480186 0,09231894 ! spindle checkpoint GO:0031577 15 7 0,000 0,03480186 0,09221727 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03480186 0,09211582 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03480186 0,09201459 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03480186 0,09191359 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03480186 0,09181281 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03480186 0,09171225 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03480186 0,0916119 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03480186 0,09151178 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03480186 0,09141188 ! fibrinolysis GO:0042730 10 7 0,000 0,03480186 0,09131219 ! eating behavior GO:0042755 7 7 0,000 0,03480186 0,09121272 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03480186 0,09111347 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03480186 0,09101444 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03480186 0,09091561 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03480186 0,09081701 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03480186 0,09071861 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03480186 0,09062043 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03480186 0,09052247 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03480186 0,09042471 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03480186 0,09032716 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03480186 0,09022983 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03480186 0,0901327 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03480186 0,09003579 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03480186 0,08993908 ! regulation of meiosis GO:0040020 12 7 0,000 0,03480186 0,08984258 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03480186 0,08974628 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03480186 0,08965019 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03480186 0,08955431 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03480186 0,08945863 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03480186 0,08936316 ! transcription termination GO:0006353 13 7 0,000 0,03480186 0,08926789 ! response to tumor cell GO:0002347 13 7 0,000 0,03480186 0,08917282 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03480186 0,08907796 ! anaphase GO:0051322 17 7 0,000 0,03480186 0,0889833 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03480186 0,08888883 ! axonal fasciculation GO:0007413 18 7 0,000 0,03480186 0,08879457 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03480186 0,08870051 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03480186 0,08860665 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03480186 0,08851298 ! diuresis GO:0030146 12 7 0,000 0,03480186 0,08841952 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03480186 0,08832625 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03480186 0,08823317 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03480186 0,0881403 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03480186 0,08804761 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03480186 0,08795513 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03480186 0,08786283 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03480186 0,08777073 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03480186 0,08767883 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03480186 0,08758711 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03480186 0,08749559 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03480186 0,08740426 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03480186 0,08731312 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03480186 0,08722217 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03480186 0,08713141 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03480186 0,08704083 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03480186 0,08695045 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03480186 0,08686025 ! adult feeding behavior GO:0008343 9 7 0,000 0,03480186 0,08677024 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03480186 0,08668042 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03480186 0,08659078 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03480186 0,08650132 ! muscle adaptation GO:0043500 14 7 0,000 0,03480186 0,08641205 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03480186 0,08632297 ! retina homeostasis GO:0001895 12 7 0,000 0,03480186 0,08623407 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03480186 0,08614535 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03480186 0,08605681 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03480186 0,08596846 ! protein prenylation GO:0018342 18 7 0,000 0,03480186 0,08588029 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03480186 0,0857923 ! regulation of cellular component size GO:0032535 109 59 1,000 0,03589565 0,08839808 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,03589565 0,08830769 ! gonad development GO:0008406 98 62 1,000 0,03928716 0,0965525 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03967433 0,09740454 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03967433 0,09730525 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03967433 0,09720616 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03967433 0,09710727 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03967433 0,09700858 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03967433 0,0969101 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03967433 0,09681181 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03967433 0,09671373 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03967433 0,09661584 ! meiotic prophase I GO:0007128 13 8 0,000 0,03967433 0,09651815 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03967433 0,09642065 ! oligopeptide transport GO:0006857 15 8 0,000 0,03967433 0,09632336 ! UTP metabolic process GO:0046051 8 8 0,000 0,03967433 0,09622626 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03967433 0,09612935 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03967433 0,09603264 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03967433 0,09593613 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03967433 0,09583981 ! succinate metabolic process GO:0006105 14 8 0,000 0,03967433 0,09574368 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03967433 0,09564774 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03967433 0,095552 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03967433 0,09545645 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03967433 0,09536109 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03967433 0,09526592 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03967433 0,09517093 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03967433 0,09507614 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03967433 0,09498154 ! reflex GO:0060004 16 8 0,000 0,03967433 0,09488712 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03967433 0,0947929 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03967433 0,09469886 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03967433 0,094605 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03967433 0,09451133 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03967433 0,09441785 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03967433 0,09432455 ! pigment granule organization GO:0048753 16 8 0,000 0,03967433 0,09423144 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03967433 0,09413851 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03967433 0,09404576 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03967433 0,0939532 ! histidine metabolic process GO:0006547 16 8 0,000 0,03967433 0,09386081 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03967433 0,09376861 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03967433 0,09367659 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03967433 0,09358475 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03967433 0,09349309 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03967433 0,09340161 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03967433 0,09331031 ! melanin metabolic process GO:0006582 15 8 0,000 0,03967433 0,09321919 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03967433 0,09312824 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03967433 0,09303747 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03967433 0,09294688 ! macrophage activation GO:0042116 12 8 0,000 0,03967433 0,09285647 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03967433 0,09276623 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03967433 0,09267616 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03967433 0,09258627 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03967433 0,09249656 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03967433 0,09240702 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03967433 0,09231765 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03967433 0,09222845 ! osteoblast development GO:0002076 16 8 0,000 0,03967433 0,09213943 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03967433 0,09205058 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03967433 0,0919619 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03967433 0,09187339 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03967433 0,09178505 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03967433 0,09169688 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03967433 0,09160887 ! response to UV-B GO:0010224 16 8 0,000 0,03967433 0,09152104 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03967433 0,09143338 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03967433 0,09134588 ! intermediate filament organization GO:0045109 12 8 0,000 0,03967433 0,09125855 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03967433 0,09117139 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03967433 0,0910844 ! cellular extravasation GO:0045123 12 8 0,000 0,03967433 0,09099757 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03967433 0,0909109 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03967433 0,0908244 ! response to antibiotic GO:0046677 11 8 0,000 0,03967433 0,09073807 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03967433 0,0906519 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03967433 0,09056589 ! DNA topological change GO:0006265 12 8 0,000 0,03967433 0,09048004 ! response to tropane GO:0014073 15 8 0,000 0,03967433 0,09039436 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03967433 0,09030884 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03967433 0,09022349 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03967433 0,09013829 ! mast cell activation GO:0045576 14 8 0,000 0,03967433 0,09005325 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03967433 0,08996838 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03967433 0,08988366 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03967433 0,0897991 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03967433 0,08971471 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03967433 0,08963047 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03967433 0,08954639 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03967433 0,08946246 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03967433 0,0893787 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03967433 0,08929509 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03967433 0,08921163 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03967433 0,08912834 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03967433 0,08904519 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03967433 0,08896221 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03967433 0,08887937 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03967433 0,0887967 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03967433 0,08871417 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03967433 0,0886318 ! hormone catabolic process GO:0042447 17 8 0,000 0,03967433 0,08854958 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03967433 0,08846751 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03967433 0,0883856 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03967433 0,08830384 ! ATP catabolic process GO:0006200 11 8 0,000 0,03967433 0,08822222 ! blastocyst growth GO:0001832 19 8 0,000 0,03967433 0,08814076 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03967433 0,08805945 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03967433 0,08797829 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03967433 0,08789728 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03967433 0,08781642 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03967433 0,08773571 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03967433 0,08765514 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03967433 0,08757472 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03967433 0,08749445 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03967433 0,08741433 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03967433 0,08733435 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03967433 0,08725452 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03967433 0,08717484 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03967433 0,0870953 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03967433 0,0870159 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03967433 0,08693666 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03967433 0,08685755 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03967433 0,08677859 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,04044377 0,0883812 ! cell redox homeostasis GO:0045454 102 64 1,000 0,04161317 0,09085416 ! germ cell development GO:0007281 118 65 1,000 0,0427952 0,09335018 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,04398971 0,09586888 ! axon extension GO:0048675 15 9 0,000 0,04452237 0,09694192 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04452237 0,09685427 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04452237 0,09676678 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04452237 0,09667944 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04452237 0,09659226 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04452237 0,09650524 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04452237 0,09641838 ! phosphate transport GO:0006817 19 9 0,000 0,04452237 0,09633167 ! reproductive behavior GO:0019098 19 9 0,000 0,04452237 0,09624512 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04452237 0,09615873 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04452237 0,09607249 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04452237 0,0959864 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04452237 0,09590047 ! GTP metabolic process GO:0046039 9 9 0,000 0,04452237 0,09581469 ! RNA methylation GO:0001510 15 9 0,000 0,04452237 0,09572906 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04452237 0,09564359 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,04452237 0,09555827 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04452237 0,0954731 ! artery development GO:0060840 24 9 0,000 0,04452237 0,09538809 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04452237 0,09530322 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04452237 0,09521851 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04452237 0,09513394 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04452237 0,09504953 ! chemosensory behavior GO:0007635 20 9 0,000 0,04452237 0,09496527 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04452237 0,09488115 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04452237 0,09479719 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04452237 0,09471337 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04452237 0,0946297 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04452237 0,09454618 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04452237 0,0944628 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04452237 0,09437958 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04452237 0,0942965 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04452237 0,09421356 ! protein targeting to ER GO:0045047 22 9 0,000 0,04452237 0,09413077 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04452237 0,09404813 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04452237 0,09396563 ! T cell selection GO:0045058 23 9 0,000 0,04452237 0,09388328 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04452237 0,09380107 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04452237 0,093719 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04452237 0,09363708 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04452237 0,0935553 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04452237 0,09347367 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04452237 0,09339217 ! mannose metabolic process GO:0006013 13 9 0,000 0,04452237 0,09331082 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04452237 0,09322961 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04452237 0,09314854 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04452237 0,09306761 ! receptor clustering GO:0043113 18 9 0,000 0,04452237 0,09298682 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04452237 0,09290618 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04452237 0,09282567 ! ruffle organization GO:0031529 15 9 0,000 0,04452237 0,0927453 ! retinol metabolic process GO:0042572 18 9 0,000 0,04452237 0,09266507 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04452237 0,09258498 ! behavioral fear response GO:0001662 22 9 0,000 0,04452237 0,09250503 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04452237 0,09242521 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04452237 0,09234554 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04452237 0,092266 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,04452237 0,09218659 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04452237 0,09210733 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04452237 0,0920282 ! segment specification GO:0007379 13 9 0,000 0,04452237 0,0919492 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04452237 0,09187034 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04452237 0,09179162 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04452237 0,09171303 ! response to amine stimulus GO:0014075 13 9 0,000 0,04452237 0,09163458 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04452237 0,09155626 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04452237 0,09147807 ! erythrocyte development GO:0048821 15 9 0,000 0,04452237 0,09140002 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04452237 0,0913221 ! renal water homeostasis GO:0003091 14 9 0,000 0,04452237 0,09124431 ! postreplication repair GO:0006301 22 9 0,000 0,04452237 0,09116666 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04452237 0,09108913 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04452237 0,09101174 ! icosanoid secretion GO:0032309 15 9 0,000 0,04452237 0,09093448 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04452237 0,09085735 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04452237 0,09078036 ! regulation of cell division GO:0051302 15 9 0,000 0,04452237 0,09070349 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04452237 0,09062675 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04452237 0,09055014 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04452237 0,09047367 ! sterol catabolic process GO:0016127 11 9 0,000 0,04452237 0,09039732 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04452237 0,0903211 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04452237 0,090245 ! S phase GO:0051320 9 9 0,000 0,04452237 0,09016904 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04452237 0,09009321 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04452237 0,0900175 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04452237 0,08994192 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04452237 0,08986646 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04452237 0,08979113 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04452237 0,08971593 ! purine base metabolic process GO:0006144 21 9 0,000 0,04452237 0,08964085 ! pigment granule transport GO:0051904 17 9 0,000 0,04452237 0,0895659 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04452237 0,08949108 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04452237 0,08941638 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04452237 0,0893418 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04452237 0,08926735 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04452237 0,08919302 ! mitochondrion localization GO:0051646 15 9 0,000 0,04452237 0,08911882 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,04519654 0,09039309 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,04519654 0,09031801 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,04519654 0,09024306 ! regulation of lipase activity GO:0060191 130 68 1,000 0,04641555 0,09260017 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,04764657 0,09497733 ! antigen processing and presentation GO:0019882 104 69 1,000 0,04764657 0,09489871 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04934609 0,09820239 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,04934609 0,09812123 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04934609 0,09804021 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04934609 0,09795932 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,04934609 0,09787856 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04934609 0,09779794 ! synapsis GO:0007129 13 10 0,000 0,04934609 0,09771744 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04934609 0,09763708 ! N-glycan processing GO:0006491 20 10 0,000 0,04934609 0,09755686 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04934609 0,09747676 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04934609 0,0973968 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04934609 0,09731696 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04934609 0,09723726 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04934609 0,09715769 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04934609 0,09707825 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04934609 0,09699893 ! androgen metabolic process GO:0008209 17 10 0,000 0,04934609 0,09691975 ! phospholipid efflux GO:0033700 16 10 0,000 0,04934609 0,0968407 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04934609 0,09676177 ! lung alveolus development GO:0048286 26 10 0,000 0,04934609 0,09668298 ! pathogenesis GO:0009405 13 10 0,000 0,04934609 0,09660431 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04934609 0,09652577 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04934609 0,09644736 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04934609 0,09636907 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04934609 0,09629091 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04934609 0,09621288 ! endoderm development GO:0007492 16 10 0,000 0,04934609 0,09613498 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04934609 0,0960572 ! arginine catabolic process GO:0006527 13 10 0,000 0,04934609 0,09597954 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04934609 0,09590201 ! proline metabolic process GO:0006560 13 10 0,000 0,04934609 0,09582461 ! L-serine metabolic process GO:0006563 18 10 0,000 0,04934609 0,09574733 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04934609 0,09567018 ! V(D)J recombination GO:0033151 28 10 0,000 0,04934609 0,09559315 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04934609 0,09551625 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04934609 0,09543946 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04934609 0,09536281 ! B cell proliferation GO:0042100 18 10 0,000 0,04934609 0,09528627 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04934609 0,09520986 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04934609 0,09513357 ! multicellular organism growth GO:0035264 18 10 0,000 0,04934609 0,0950574 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04934609 0,09498136 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04934609 0,09490543 ! epithelial cell development GO:0002064 20 10 0,000 0,04934609 0,09482963 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04934609 0,09475395 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04934609 0,09467838 ! macroautophagy GO:0016236 17 10 0,000 0,04934609 0,09460294 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04934609 0,09452762 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04934609 0,09445242 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04934609 0,09437734 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04934609 0,09430238 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04934609 0,09422754 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04934609 0,09415281 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04934609 0,0940782 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04934609 0,09400372 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04934609 0,09392935 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04934609 0,09385509 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04934609 0,09378096 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04934609 0,09370694 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04934609 0,09363304 ! response to dsRNA GO:0043331 20 10 0,000 0,04934609 0,09355925 ! DNA ligation GO:0006266 19 10 0,000 0,04934609 0,09348559 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04934609 0,09341203 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04934609 0,0933386 ! melanosome localization GO:0032400 16 10 0,000 0,04934609 0,09326527 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04934609 0,09319207 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04934609 0,09311898 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04934609 0,093046 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04934609 0,09297314 ! mRNA cleavage GO:0006379 17 10 0,000 0,04934609 0,09290039 ! protein sumoylation GO:0016925 15 10 0,000 0,04934609 0,09282775 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04934609 0,09275523 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04934609 0,09268282 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04934609 0,09261053 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04934609 0,09253834 ! salivary gland development GO:0007431 27 10 0,000 0,04934609 0,09246627 ! prophase GO:0051324 15 10 0,000 0,04934609 0,09239431 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04934609 0,09232247 ! apical protein localization GO:0045176 15 10 0,000 0,04934609 0,09225073 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04934609 0,09217911 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04934609 0,0921076 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04934609 0,0920362 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04934609 0,09196491 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04934609 0,09189373 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04934609 0,09182266 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04934609 0,0917517 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04934609 0,09168084 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04934609 0,0916101 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04934609 0,09153947 ! detection of calcium ion GO:0005513 23 10 0,000 0,04934609 0,09146895 ! oocyte development GO:0048599 17 10 0,000 0,04934609 0,09139853 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04934609 0,09132823 ! blastocyst formation GO:0001825 17 10 0,000 0,04934609 0,09125803 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04934609 0,09118794 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04934609 0,09111795 ! activation of innate immune response GO:0002218 12 10 0,000 0,04934609 0,09104808 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04934609 0,09097831 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04934609 0,09090865 ! response to nicotine GO:0035094 20 10 0,000 0,04934609 0,09083909 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04934609 0,09076964 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04934609 0,0907003 ! amine catabolic process GO:0009310 117 71 1,000 0,05014406 0,09209665 ! reproductive structure development GO:0048608 113 71 1,000 0,05014406 0,0920264 ! regulation of immune effector process GO:0002697 137 71 1,000 0,05014406 0,09195626 ! carbohydrate transport GO:0008643 110 72 1,000 0,05141024 0,09420642 ! regulation of blood pressure GO:0008217 125 73 1,000 0,05268784 0,09647408 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,05397671 0,09875892 GO:0090046|regulation of transcription regulator activity, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,05397671 0,09868387 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05414562 0,09891751 ! respiratory burst GO:0045730 17 11 0,000 0,05414562 0,09884246 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05414562 0,09876752 ! neuron fate specification GO:0048665 17 11 0,000 0,05414562 0,0986927 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05414562 0,09861799 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05414562 0,09854339 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05414562 0,0984689 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05414562 0,09839453 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05414562 0,09832027 ! response to pain GO:0048265 24 11 0,000 0,05414562 0,09824612 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05414562 0,09817209 ! T cell proliferation GO:0042098 26 11 0,000 0,05414562 0,09809816 ! blood vessel remodeling GO:0001974 29 11 0,000 0,05414562 0,09802435 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,05414562 0,09795065 ! bone resorption GO:0045453 16 11 0,000 0,05414562 0,09787705 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05414562 0,09780357 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05414562 0,0977302 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05414562 0,09765694 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05414562 0,09758379 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05414562 0,09751075 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05414562 0,09743782 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05414562 0,09736499 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05414562 0,09729228 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05414562 0,09721967 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05414562 0,09714717 ! lipid digestion GO:0044241 18 11 0,000 0,05414562 0,09707478 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05414562 0,0970025 ! UV protection GO:0009650 19 11 0,000 0,05414562 0,09693033 ! adult heart development GO:0007512 14 11 0,000 0,05414562 0,09685826 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,05414562 0,0967863 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05414562 0,09671445 ! temperature homeostasis GO:0001659 17 11 0,000 0,05414562 0,0966427 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05414562 0,09657106 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05414562 0,09649953 ! regulation of organ growth GO:0046620 13 11 0,000 0,05414562 0,0964281 ! pigment granule localization GO:0051875 20 11 0,000 0,05414562 0,09635677 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05414562 0,09628556 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05414562 0,09621445 ! embryonic axis specification GO:0000578 18 11 0,000 0,05414562 0,09614344 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05414562 0,09607254 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05414562 0,09600174 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05414562 0,09593104 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05414562 0,09586046 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05414562 0,09578997 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05414562 0,09571959 ! zymogen activation GO:0031638 15 11 0,000 0,05414562 0,09564931 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05414562 0,09557913 ! nucleosome positioning GO:0016584 15 11 0,000 0,05414562 0,09550906 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05414562 0,09543909 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05414562 0,09536922 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05414562 0,09529946 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,05414562 0,09522979 ! acid secretion GO:0046717 18 11 0,000 0,05414562 0,09516023 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05414562 0,09509077 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05414562 0,09502141 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05414562 0,09495216 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05414562 0,094883 ! oocyte differentiation GO:0009994 18 11 0,000 0,05414562 0,09481394 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05414562 0,09474499 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,05414562 0,09467613 ! cholesterol efflux GO:0033344 19 11 0,000 0,05414562 0,09460738 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05414562 0,09453872 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05414562 0,09447017 ! germ cell migration GO:0008354 25 11 0,000 0,05414562 0,09440171 ! embryonic gut development GO:0048566 15 11 0,000 0,05414562 0,09433335 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05414562 0,09426509 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05414562 0,09419693 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05414562 0,09412887 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05414562 0,09406091 ! defense response to fungus GO:0050832 13 11 0,000 0,05414562 0,09399304 ! lysogeny GO:0030069 21 11 0,000 0,05414562 0,09392528 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05414562 0,09385761 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05414562 0,09379004 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05414562 0,09372256 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05414562 0,09365518 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05414562 0,0935879 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,05527672 0,09547437 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,05527672 0,09540588 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,05527672 0,09533749 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,05527672 0,0952692 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,05658772 0,09745888 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,05790957 0,0996641 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,05790957 0,09959287 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05892107 0,10126008 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05892107 0,1011878 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05892107 0,10111562 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,05892107 0,10104355 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05892107 0,10097158 ! cartilage condensation GO:0001502 20 12 0,000 0,05892107 0,10089972 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05892107 0,10082796 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05892107 0,10075629 ! protein complex disassembly GO:0043241 27 12 0,000 0,05892107 0,10068473 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05892107 0,10061328 ! hippocampus development GO:0021766 26 12 0,000 0,05892107 0,10054192 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05892107 0,10047066 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05892107 0,10039951 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05892107 0,10032845 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05892107 0,1002575 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05892107 0,10018665 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05892107 0,10011589 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05892107 0,10004524 ! drug transport GO:0015893 16 12 0,000 0,05892107 0,09997469 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05892107 0,09990423 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05892107 0,09983388 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05892107 0,09976362 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05892107 0,09969346 ! focal adhesion formation GO:0048041 35 12 0,000 0,05892107 0,0996234 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05892107 0,09955344 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05892107 0,09948358 ! forebrain cell migration GO:0021885 21 12 0,000 0,05892107 0,09941382 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05892107 0,09934415 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05892107 0,09927458 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05892107 0,09920511 ! fear response GO:0042596 26 12 0,000 0,05892107 0,09913574 ! monoamine transport GO:0015844 18 12 0,000 0,05892107 0,09906646 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05892107 0,09899728 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05892107 0,0989282 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05892107 0,09885921 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05892107 0,09879032 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05892107 0,09872152 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05892107 0,09865282 ! protein homotetramerization GO:0051289 21 12 0,000 0,05892107 0,09858422 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05892107 0,09851571 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05892107 0,0984473 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05892107 0,09837898 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05892107 0,09831075 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05892107 0,09824262 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05892107 0,09817459 ! cranial nerve development GO:0021545 20 12 0,000 0,05892107 0,09810665 ! fucose catabolic process GO:0019317 22 12 0,000 0,05892107 0,0980388 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05892107 0,09797105 ! histone methylation GO:0016571 26 12 0,000 0,05892107 0,09790339 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05892107 0,09783582 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05892107 0,09776835 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05892107 0,09770097 ! spleen development GO:0048536 22 12 0,000 0,05892107 0,09763368 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05892107 0,09756649 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05892107 0,09749938 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05892107 0,09743237 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05892107 0,09736546 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05892107 0,09729863 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,05892107 0,0972319 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05892107 0,09716525 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05892107 0,0970987 ! response to cold GO:0009409 17 12 0,000 0,05892107 0,09703224 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05892107 0,09696587 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05892107 0,09689959 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,05924212 0,09736102 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,06058523 0,09950039 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,06058523 0,09943252 ! T cell activation GO:0042110 168 81 1,000 0,06330261 0,10382145 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,06330261 0,10375073 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,06330261 0,1036801 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06367258 0,10421512 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06367258 0,10414427 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06367258 0,10407352 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06367258 0,10400287 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06367258 0,10393231 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06367258 0,10386184 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06367258 0,10379148 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06367258 0,10372121 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06367258 0,10365103 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06367258 0,10358095 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06367258 0,10351096 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06367258 0,10344107 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06367258 0,10337127 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06367258 0,10330157 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06367258 0,10323196 ! methionine metabolic process GO:0006555 27 13 0,000 0,06367258 0,10316244 ! plasma membrane organization GO:0007009 24 13 0,000 0,06367258 0,10309302 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06367258 0,10302369 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06367258 0,10295445 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06367258 0,10288531 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06367258 0,10281626 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06367258 0,1027473 ! response to X-ray GO:0010165 25 13 0,000 0,06367258 0,10267843 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06367258 0,10260966 ! exocrine system development GO:0035272 32 13 0,000 0,06367258 0,10254098 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06367258 0,10247239 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06367258 0,10240389 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06367258 0,10233549 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06367258 0,10226717 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06367258 0,10219895 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06367258 0,10213081 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06367258 0,10206277 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06367258 0,10199482 ! regulation of cellular pH GO:0030641 22 13 0,000 0,06367258 0,10192696 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06367258 0,10185919 ! ribosome assembly GO:0042255 17 13 0,000 0,06367258 0,10179151 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06367258 0,10172392 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06367258 0,10165642 ! chromatin silencing GO:0006342 26 13 0,000 0,06367258 0,10158901 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06367258 0,10152168 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06367258 0,10145445 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06367258 0,10138731 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06367258 0,10132025 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06367258 0,10125329 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,06367258 0,10118641 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06367258 0,10111962 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06367258 0,10105292 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06367258 0,1009863 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06367258 0,10091978 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06367258 0,10085334 ! embryonic placenta development GO:0001892 23 13 0,000 0,06367258 0,10078699 ! insulin secretion GO:0030073 23 13 0,000 0,06367258 0,10072072 ! actin filament polymerization GO:0030041 24 13 0,000 0,06367258 0,10065455 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06367258 0,10058846 ! acrosome reaction GO:0007340 18 13 0,000 0,06367258 0,10052245 ! negative regulation of growth GO:0045926 155 84 1,000 0,06745447 0,10642325 ! rRNA transcription GO:0009303 25 14 0,000 0,06840025 0,10784469 ! lactation GO:0007595 26 14 0,000 0,06840025 0,10777406 ! reproductive cellular process GO:0048610 20 14 0,000 0,06840025 0,10770353 ! tRNA modification GO:0006400 20 14 0,000 0,06840025 0,10763309 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06840025 0,10756274 ! regulation of S phase GO:0033261 23 14 0,000 0,06840025 0,10749248 ! water transport GO:0006833 21 14 0,000 0,06840025 0,10742232 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06840025 0,10735225 ! non-recombinational repair GO:0000726 25 14 0,000 0,06840025 0,10728226 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06840025 0,10721237 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06840025 0,10714257 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06840025 0,10707287 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,06840025 0,10700325 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06840025 0,10693372 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06840025 0,10686428 ! palate development GO:0060021 31 14 0,000 0,06840025 0,10679493 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06840025 0,10672568 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06840025 0,10665651 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06840025 0,10658743 ! arginine metabolic process GO:0006525 17 14 0,000 0,06840025 0,10651844 ! regulation of heart rate GO:0002027 24 14 0,000 0,06840025 0,10644954 ! organic alcohol transport GO:0015850 29 14 0,000 0,06840025 0,10638073 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,06840025 0,10631201 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06840025 0,10624338 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,06840025 0,10617484 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06840025 0,10610638 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06840025 0,10603801 ! L-amino acid transport GO:0015807 30 14 0,000 0,06840025 0,10596973 ! bone mineralization GO:0030282 17 14 0,000 0,06840025 0,10590154 ! stem cell development GO:0048864 43 14 0,000 0,06840025 0,10583344 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06840025 0,10576542 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,06840025 0,10569749 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06840025 0,10562965 ! cerebellum development GO:0021549 21 14 0,000 0,06840025 0,1055619 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06840025 0,10549423 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06840025 0,10542665 ! response to gamma radiation GO:0010332 28 14 0,000 0,06840025 0,10535915 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06840025 0,10529174 ! cofactor transport GO:0051181 26 14 0,000 0,06840025 0,10522442 ! NADP metabolic process GO:0006739 24 14 0,000 0,06840025 0,10515718 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,06840025 0,10509003 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06840025 0,10502297 ! intestinal absorption GO:0050892 25 14 0,000 0,06840025 0,10495599 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06840025 0,1048891 ! oxygen transport GO:0015671 21 14 0,000 0,06840025 0,10482229 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06840025 0,10475557 ! male genitalia development GO:0030539 24 14 0,000 0,06840025 0,10468893 ! regulation of axon extension GO:0030516 37 14 0,000 0,06840025 0,10462237 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,06840025 0,10455591 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06840025 0,10448952 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,0688581 0,10512219 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 0,07027134 0,1072117 ! mitochondrion organization GO:0007005 148 86 1,000 0,07027134 0,10714375 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,07169407 0,10924378 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0731042 0,11132197 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0731042 0,11125156 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0731042 0,11118123 ! superoxide anion generation GO:0042554 20 15 0,000 0,0731042 0,111111 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0731042 0,11104085 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0731042 0,1109708 ! copper ion transport GO:0006825 20 15 0,000 0,0731042 0,11090083 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0731042 0,11083095 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0731042 0,11076115 ! response to cAMP GO:0051591 22 15 0,000 0,0731042 0,11069145 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0731042 0,11062183 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0731042 0,1105523 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0731042 0,11048286 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0731042 0,1104135 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0731042 0,11034424 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0731042 0,11027505 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0731042 0,11020596 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0731042 0,11013695 ! pituitary gland development GO:0021983 29 15 0,000 0,0731042 0,11006803 ! vesicle coating GO:0006901 33 15 0,000 0,0731042 0,10999919 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0731042 0,10993044 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0731042 0,10986178 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0731042 0,1097932 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0731042 0,10972471 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0731042 0,1096563 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0731042 0,10958798 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0731042 0,10951975 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0731042 0,10945159 ! histone deacetylation GO:0016575 20 15 0,000 0,0731042 0,10938353 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0731042 0,10931554 ! tissue regeneration GO:0042246 26 15 0,000 0,0731042 0,10924765 ! water homeostasis GO:0030104 27 15 0,000 0,0731042 0,10917983 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0731042 0,1091121 ! muscle maintenance GO:0046716 26 15 0,000 0,0731042 0,10904446 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0731042 0,1089769 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0731042 0,10890942 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0731042 0,10884202 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0731042 0,10877471 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0731042 0,10870748 ! cell killing GO:0001906 29 15 0,000 0,0731042 0,10864034 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0731042 0,10857328 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0731042 0,1085063 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0731042 0,1084394 ! peptide hormone processing GO:0016486 23 15 0,000 0,0731042 0,10837259 ! regulation of DNA binding GO:0051101 155 88 1,000 0,07312615 0,10833837 ! regulation of neurological system process GO:0031644 148 88 1,000 0,07312615 0,1082717 ! sex differentiation GO:0007548 145 90 1,000 0,07601786 0,112484 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,07778456 0,11502745 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07778456 0,11495679 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07778456 0,11488622 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,07778456 0,11481574 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,07778456 0,11474534 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07778456 0,11467503 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,07778456 0,11460481 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,07778456 0,11453467 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,07778456 0,11446462 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,07778456 0,11439465 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,07778456 0,11432477 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,07778456 0,11425498 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07778456 0,11418527 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07778456 0,11411564 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07778456 0,1140461 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,07778456 0,11397665 ! response to osmotic stress GO:0006970 25 16 0,000 0,07778456 0,11390728 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,07778456 0,11383799 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,07778456 0,11376879 ! fructose metabolic process GO:0006000 25 16 0,000 0,07778456 0,11369967 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07778456 0,11363063 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07778456 0,11356168 ! intermediate filament-based process GO:0045103 32 16 0,000 0,07778456 0,11349282 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,07778456 0,11342403 ! axon cargo transport GO:0008088 43 16 0,000 0,07778456 0,11335533 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07778456 0,11328672 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,07778456 0,11321818 ! DNA replication initiation GO:0006270 27 16 0,000 0,07778456 0,11314973 ! neuron recognition GO:0008038 35 16 0,000 0,07778456 0,11308136 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,07778456 0,11301308 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07778456 0,11294487 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,07778456 0,11287675 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07778456 0,11280871 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,07778456 0,11274076 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07778456 0,11267288 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07778456 0,11260509 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07778456 0,11253737 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,07778456 0,11246974 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,07778456 0,11240219 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07778456 0,11233473 ! defense response to virus GO:0051607 37 16 0,000 0,07778456 0,11226734 ! regulation of defense response GO:0031347 149 92 1,000 0,07894546 0,11387456 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,08042239 0,11593546 ! regulation of membrane potential GO:0042391 164 93 1,000 0,08042239 0,11586603 ! regulation of T cell activation GO:0050863 158 94 1,000 0,08190792 0,11793565 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,08244144 0,11863284 ! metencephalon development GO:0022037 30 17 0,000 0,08244144 0,11856193 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,08244144 0,1184911 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,08244144 0,11842036 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,08244144 0,11834971 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,08244144 0,11827913 ! gene silencing by RNA GO:0031047 36 17 0,000 0,08244144 0,11820865 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,08244144 0,11813824 ! glial cell development GO:0021782 27 17 0,000 0,08244144 0,11806792 ! limbic system development GO:0021761 36 17 0,000 0,08244144 0,11799768 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,08244144 0,11792753 ! adult walking behavior GO:0007628 33 17 0,000 0,08244144 0,11785746 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,08244144 0,11778747 ! heart looping GO:0001947 30 17 0,000 0,08244144 0,11771757 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,08244144 0,11764775 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,08244144 0,11757801 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,08244144 0,11750836 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,08244144 0,11743878 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,08244144 0,11736929 ! NAD metabolic process GO:0019674 29 17 0,000 0,08244144 0,11729989 ! membrane budding GO:0006900 37 17 0,000 0,08244144 0,11723056 ! DNA integration GO:0015074 29 17 0,000 0,08244144 0,11716132 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,08244144 0,11709215 ! regulation of protein binding GO:0043393 33 17 0,000 0,08244144 0,11702307 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,08244144 0,11695407 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,08244144 0,11688515 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,08244144 0,11681632 ! genitalia development GO:0048806 30 17 0,000 0,08244144 0,11674756 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,08244144 0,11667889 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,08244144 0,11661029 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,08244144 0,11654178 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,08244144 0,11647335 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,08244144 0,11640499 ! steroid catabolic process GO:0006706 31 17 0,000 0,08244144 0,11633672 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,08244144 0,11626853 ! gas transport GO:0015669 25 17 0,000 0,08244144 0,11620041 ! organic cation transport GO:0015695 31 17 0,000 0,08244144 0,11613238 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,08244144 0,11606443 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,08244144 0,11599655 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,08244144 0,11592876 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,08244144 0,11586104 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,08244144 0,11579341 ! protein ubiquitination GO:0016567 217 97 1,000 0,08641486 0,12130347 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08707496 0,12215881 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08707496 0,12208762 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08707496 0,12201651 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,08707496 0,12194549 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08707496 0,12187455 ! memory GO:0007613 31 18 0,000 0,08707496 0,12180369 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08707496 0,12173292 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08707496 0,12166223 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08707496 0,12159161 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08707496 0,12152109 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08707496 0,12145064 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,08707496 0,12138027 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08707496 0,12130999 ! response to retinoic acid GO:0032526 26 18 0,000 0,08707496 0,12123979 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,08707496 0,12116967 ! response to fungus GO:0009620 21 18 0,000 0,08707496 0,12109963 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,08707496 0,12102967 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,08707496 0,12095979 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08707496 0,12088999 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08707496 0,12082027 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08707496 0,12075064 ! vitamin transport GO:0051180 27 18 0,000 0,08707496 0,12068108 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,08707496 0,1206116 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08707496 0,12054221 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08707496 0,12047289 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08707496 0,12040365 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08707496 0,12033449 ! nerve development GO:0021675 28 18 0,000 0,08707496 0,12026541 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08707496 0,12019642 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,08793355 0,121312 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,08946023 0,12334746 ! protein secretion GO:0009306 39 19 0,000 0,09168523 0,12634288 ! positive regulation of translation GO:0045727 30 19 0,000 0,09168523 0,12627056 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09168523 0,12619832 ! skin development GO:0043588 36 19 0,000 0,09168523 0,12612617 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,09168523 0,1260541 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09168523 0,12598211 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09168523 0,1259102 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09168523 0,12583837 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09168523 0,12576663 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09168523 0,12569497 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,09168523 0,12562339 ! cerebral cortex development GO:0021987 36 19 0,000 0,09168523 0,12555189 ! pigmentation during development GO:0048066 41 19 0,000 0,09168523 0,12548047 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09168523 0,12540914 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,09168523 0,12533788 ! heme metabolic process GO:0042168 36 19 0,000 0,09168523 0,12526671 ! actin filament bundle formation GO:0051017 42 19 0,000 0,09168523 0,12519561 ! neuromuscular junction development GO:0007528 34 19 0,000 0,09168523 0,1251246 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09168523 0,12505367 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09168523 0,12498282 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,09168523 0,12491204 ! peptide cross-linking GO:0018149 37 19 0,000 0,09168523 0,12484135 ! protein export from nucleus GO:0006611 36 19 0,000 0,09168523 0,12477074 ! heart process GO:0003015 30 19 0,000 0,09168523 0,12470021 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09168523 0,12462976 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,09168523 0,12455938 ! visual learning GO:0008542 36 19 0,000 0,09168523 0,12448909 ! cellular pigmentation GO:0033059 36 19 0,000 0,09168523 0,12441888 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,09168523 0,12434874 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09168523 0,12427869 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,09168523 0,12420871 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09168523 0,12413881 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09168523 0,12406899 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09168523 0,12399925 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09168523 0,12392959 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09168523 0,12386001 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09168523 0,1237905 ! cilium assembly GO:0042384 37 19 0,000 0,09168523 0,12372107 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09168523 0,12365172 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,09627238 0,12976545 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,09627238 0,1296928 ! positive regulation of ossification GO:0045778 47 20 0,000 0,09627238 0,12962022 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,09627238 0,12954773 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,09627238 0,12947531 ! cAMP metabolic process GO:0046058 36 20 0,000 0,09627238 0,12940298 ! response to vitamin GO:0033273 31 20 0,000 0,09627238 0,12933073 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,09627238 0,12925856 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,09627238 0,12918647 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,09627238 0,12911446 ! response to alkaloid GO:0043279 38 20 0,000 0,09627238 0,12904253 ! retinoid metabolic process GO:0001523 32 20 0,000 0,09627238 0,12897068 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,09627238 0,12889891 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,09627238 0,12882722 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,09627238 0,12875561 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,09627238 0,12868408 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,09627238 0,12861262 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,09627238 0,12854125 ! body fluid secretion GO:0007589 31 20 0,000 0,09627238 0,12846996 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,09627238 0,12839875 ! peptide secretion GO:0002790 35 20 0,000 0,09627238 0,12832761 ! stem cell differentiation GO:0048863 53 20 0,000 0,09627238 0,12825655 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,09627238 0,12818558 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,09627238 0,12811468 ! sensory perception of pain GO:0019233 30 20 0,000 0,09627238 0,12804386 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,09627238 0,12797311 ! diencephalon development GO:0021536 34 20 0,000 0,09627238 0,12790245 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,09627238 0,12783186 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,09627238 0,12776135 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,09627238 0,12769092 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,09627238 0,12762057 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,09627238 0,1275503 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,09627238 0,1274801 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,09627238 0,12740998 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,09627238 0,12733993 ! actin filament-based movement GO:0030048 43 20 0,000 0,09627238 0,12726997 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,09627238 0,12720007 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,09627238 0,12713026 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,09627238 0,12706052 ! negative regulation of translation GO:0017148 29 20 0,000 0,09627238 0,12699086 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,09627238 0,12692128 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,09627238 0,12685177 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10083651 0,1327929 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10083651 0,13272026 ! hormone secretion GO:0046879 38 21 0,000 0,10083651 0,13264769 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10083651 0,13257521 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10083651 0,1325028 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10083651 0,13243048 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10083651 0,13235823 ! axis specification GO:0009798 38 21 0,000 0,10083651 0,13228606 ! ovarian follicle development GO:0001541 35 21 0,000 0,10083651 0,13221397 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10083651 0,13214196 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,10083651 0,13207002 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10083651 0,13199817 ! cell aging GO:0007569 44 21 0,000 0,10083651 0,13192639 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10083651 0,13185469 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,10083651 0,13178307 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,10083651 0,13171153 ! cytolysis GO:0019835 24 21 0,000 0,10083651 0,13164006 ! vasodilation GO:0042311 39 21 0,000 0,10083651 0,13156867 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10083651 0,13149736 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10083651 0,13142613 ! oogenesis GO:0048477 36 21 0,000 0,10083651 0,13135497 ! DNA modification GO:0006304 34 21 0,000 0,10083651 0,13128389 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,10083651 0,13121289 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,10083651 0,13114196 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10083651 0,13107111 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,10083651 0,13100034 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,10083651 0,13092964 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10083651 0,13085902 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10083651 0,13078848 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,10083651 0,13071801 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10083651 0,13064762 ! collagen catabolic process GO:0030574 28 21 0,000 0,10083651 0,1305773 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10083651 0,13050706 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,10537773 0,1363112 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,10537773 0,13623795 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,10537773 0,13616479 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,10537773 0,1360917 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,10537773 0,13601869 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,10537773 0,13594575 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,10537773 0,1358729 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,10537773 0,13580012 ! regeneration GO:0031099 41 22 0,000 0,10537773 0,13572743 ! keratinization GO:0031424 28 22 0,000 0,10537773 0,1356548 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,10537773 0,13558226 ! sensory perception of taste GO:0050909 28 22 0,000 0,10537773 0,1355098 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,10537773 0,13543741 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,10537773 0,1353651 ! vacuolar transport GO:0007034 36 22 0,000 0,10537773 0,13529287 ! lysosome organization GO:0007040 41 22 0,000 0,10537773 0,13522071 ! central nervous system neuron development GO:0021954 46 22 0,000 0,10537773 0,13514863 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,10537773 0,13507663 ! fucose metabolic process GO:0006004 39 22 0,000 0,10537773 0,1350047 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,10537773 0,13493285 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,10537773 0,13486108 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,10537773 0,13478938 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,10537773 0,13471776 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,10537773 0,13464622 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,10537773 0,13457475 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,10537773 0,13450336 ! sarcomere organization GO:0045214 30 22 0,000 0,10537773 0,13443204 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,10537773 0,1343608 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,10537773 0,13428963 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,10537773 0,13421854 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,10537773 0,13414753 ! protein stabilization GO:0050821 39 22 0,000 0,10537773 0,13407659 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,10989618 0,1397517 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,10989618 0,13967787 ! gluconeogenesis GO:0006094 33 23 0,000 0,10989618 0,13960412 ! viral genome replication GO:0019079 41 23 0,000 0,10989618 0,13953045 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,10989618 0,13945686 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,10989618 0,13938335 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,10989618 0,13930991 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,10989618 0,13923655 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,10989618 0,13916327 ! visual behavior GO:0007632 42 23 0,000 0,10989618 0,13909006 ! response to ethanol GO:0045471 46 23 0,000 0,10989618 0,13901693 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,10989618 0,13894388 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,10989618 0,13887091 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,10989618 0,13879801 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,10989618 0,13872519 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,10989618 0,13865244 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,10989618 0,13857977 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,10989618 0,13850718 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,10989618 0,13843466 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,10989618 0,13836222 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,10989618 0,13828986 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,10989618 0,13821757 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,10989618 0,13814535 ! fatty acid transport GO:0015908 44 23 0,000 0,10989618 0,13807322 ! platelet activation GO:0030168 37 23 0,000 0,10989618 0,13800115 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,10989618 0,13792916 ! hormone transport GO:0009914 40 23 0,000 0,10989618 0,13785725 ! cell-cell recognition GO:0009988 25 23 0,000 0,10989618 0,13778541 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,10989618 0,13771365 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,10989618 0,13764196 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,10989618 0,13757035 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,10989618 0,13749881 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,10989618 0,13742734 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,11439195 0,14297508 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,11439195 0,14290085 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,11439195 0,14282669 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,11439195 0,14275261 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,11439195 0,14267861 ! spinal cord development GO:0021510 47 24 0,000 0,11439195 0,14260468 ! vacuole organization GO:0007033 43 24 0,000 0,11439195 0,14253083 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,11439195 0,14245706 ! digestive system process GO:0022600 39 24 0,000 0,11439195 0,14238336 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,11439195 0,14230974 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,11439195 0,14223619 ! regulation of behavior GO:0050795 43 24 0,000 0,11439195 0,14216273 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,11439195 0,14208933 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,11439195 0,14201601 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,11439195 0,14194277 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,11439195 0,14186961 ! pallium development GO:0021543 49 24 0,000 0,11439195 0,14179652 ! pentose metabolic process GO:0019321 35 24 0,000 0,11439195 0,1417235 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,11439195 0,14165056 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,11439195 0,14157769 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,11439195 0,1415049 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,11439195 0,14143219 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,11439195 0,14135955 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,11439195 0,14128698 ! regulation of amine transport GO:0051952 40 24 0,000 0,11439195 0,14121449 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,11886517 0,14666133 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,11886517 0,14658616 ! myelination GO:0042552 45 25 0,000 0,11886517 0,14651106 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,11886517 0,14643604 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,11886517 0,1463611 ! phototransduction GO:0007602 33 25 0,000 0,11886517 0,14628623 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,11886517 0,14621145 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,11886517 0,14613673 ! sperm motility GO:0030317 31 25 0,000 0,11886517 0,1460621 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,11886517 0,14598754 ! receptor metabolic process GO:0043112 46 25 0,000 0,11886517 0,14591306 ! chromosome condensation GO:0030261 45 25 0,000 0,11886517 0,14583865 ! response to starvation GO:0042594 42 25 0,000 0,11886517 0,14576432 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,11886517 0,14569006 ! negative regulation of cell development GO:0010721 73 25 0,000 0,11886517 0,14561588 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,11886517 0,14554178 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,11886517 0,14546775 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,11886517 0,14539379 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,11886517 0,14531991 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,11886517 0,14524611 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,11886517 0,14517238 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,11886517 0,14509873 ! telomere organization GO:0032200 43 25 0,000 0,11886517 0,14502515 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,11886517 0,14495164 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,11886517 0,14487821 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,12331593 0,1502269 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,12331593 0,15015088 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,12331593 0,15007493 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,12331593 0,14999906 ! tube lumen formation GO:0035148 50 26 0,000 0,12331593 0,14992326 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,12331593 0,14984754 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,12331593 0,1497719 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,12331593 0,14969633 GO:0051297|centrosome organization, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,12331593 0,14962084 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,12331593 0,14954543 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,12331593 0,14947009 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,12331593 0,14939483 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,12331593 0,14931965 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,12331593 0,14924453 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,12331593 0,1491695 ! blastocyst development GO:0001824 49 26 0,000 0,12331593 0,14909454 ! leukocyte proliferation GO:0070661 52 26 0,000 0,12331593 0,14901966 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,12331593 0,14894485 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,12774437 0,15421623 ! neuron fate commitment GO:0048663 48 27 0,000 0,12774437 0,15413889 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,12774437 0,15406163 ! iron ion transport GO:0006826 59 27 0,000 0,12774437 0,15398444 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,12774437 0,15390733 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,12774437 0,1538303 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,12774437 0,15375335 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,12774437 0,15367647 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,12774437 0,15359967 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,12774437 0,15352295 ! autophagy GO:0006914 41 27 0,000 0,12774437 0,1534463 ! male gonad development GO:0008584 44 27 0,000 0,12774437 0,15336973 ! response to toxin GO:0009636 47 27 0,000 0,12774437 0,15329324 ! primary neural tube formation GO:0014020 51 27 0,000 0,12774437 0,15321682 ! base-excision repair GO:0006284 41 27 0,000 0,12774437 0,15314048 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,12774437 0,15306422 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,12774437 0,15298803 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,12774437 0,15291191 ! glutathione metabolic process GO:0006749 39 27 0,000 0,12774437 0,15283588 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,12774437 0,15275991 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,12774437 0,15268403 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,12774437 0,15260822 ! circadian rhythm GO:0007623 50 28 0,000 0,13215058 0,15779369 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,13215058 0,15771542 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,13215058 0,15763723 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,13215058 0,15755911 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,13215058 0,15748107 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,13215058 0,15740311 ! synaptogenesis GO:0007416 42 28 0,000 0,13215058 0,15732523 ! lipid oxidation GO:0034440 43 28 0,000 0,13215058 0,15724742 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,13215058 0,15716969 ! translational initiation GO:0006413 65 29 0,000 0,13653467 0,16230357 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,13653467 0,16222342 ! regulation of pH GO:0006885 43 29 0,000 0,13653467 0,16214335 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,13653467 0,16206336 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,13653467 0,16198344 ! catechol metabolic process GO:0009712 54 29 0,000 0,13653467 0,16190361 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,13653467 0,16182385 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,13653467 0,16174418 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,13653467 0,16166458 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,13653467 0,16158506 ! cell fate determination GO:0001709 60 29 0,000 0,13653467 0,16150562 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,13653467 0,16142625 ! detection of light stimulus GO:0009583 38 29 0,000 0,13653467 0,16134697 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,13653467 0,16126776 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,13653467 0,16118863 ! tissue homeostasis GO:0001894 48 29 0,000 0,13653467 0,16110958 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,14089677 0,16617531 ! zinc ion transport GO:0006829 45 30 0,000 0,14089677 0,16609389 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,14089677 0,16601255 ! cell junction assembly GO:0034329 78 30 0,000 0,14089677 0,16593129 ! regulation of innate immune response GO:0045088 51 30 0,000 0,14089677 0,16585011 ! acute-phase response GO:0006953 49 30 0,000 0,14089677 0,16576901 ! myofibril assembly GO:0030239 47 30 0,000 0,14089677 0,16568799 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,14089677 0,16560705 ! phospholipid transport GO:0015914 51 30 0,000 0,14089677 0,16552619 ! ensheathment of neurons GO:0007272 57 30 0,000 0,14089677 0,1654454 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,14089677 0,1653647 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,14089677 0,16528407 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,14089677 0,16520352 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,14089677 0,16512305 ! eye morphogenesis GO:0048592 60 30 0,000 0,14089677 0,16504266 ! regulation of B cell activation GO:0050864 50 30 0,000 0,14089677 0,16496235 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,14523697 0,16996117 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,14523697 0,16987854 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,14523697 0,16979599 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,14523697 0,16971353 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,14523697 0,16963114 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,14523697 0,16954884 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,14523697 0,16946661 ! ovulation cycle process GO:0022602 49 31 0,000 0,14523697 0,16938447 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,14523697 0,1693024 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,14523697 0,16922041 ! peptide transport GO:0015833 55 31 0,000 0,14523697 0,16913851 ! iron ion homeostasis GO:0055072 54 31 0,000 0,14523697 0,16905668 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,14523697 0,16897493 ! natural killer cell activation GO:0030101 45 31 0,000 0,14523697 0,16889326 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,14523697 0,16881167 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,14523697 0,16873016 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,14523697 0,16864872 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,14523697 0,16856737 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,14955539 0,17349579 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,14955539 0,17341218 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,14955539 0,17332865 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,14955539 0,1732452 ! spliceosome assembly GO:0000245 67 32 0,000 0,14955539 0,17316183 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,14955539 0,17307853 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,14955539 0,17299532 ! response to ionizing radiation GO:0010212 65 32 0,000 0,14955539 0,17291219 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,14955539 0,17282914 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,14955539 0,17274617 ! muscle cell development GO:0055001 49 32 0,000 0,14955539 0,17266328 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,14955539 0,17258047 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,14955539 0,17249773 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,14955539 0,17241508 ! ovulation cycle GO:0042698 51 32 0,000 0,14955539 0,17233251 ! peripheral nervous system development GO:0007422 64 32 0,000 0,14955539 0,17225001 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,14955539 0,1721676 ! gene silencing GO:0016458 65 32 0,000 0,14955539 0,17208526 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,15385214 0,17694467 ! post-embryonic development GO:0009791 69 33 0,000 0,15385214 0,17686013 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,15385214 0,17677567 ! protein targeting to membrane GO:0006612 68 33 0,000 0,15385214 0,17669129 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,15385214 0,17660699 ! ceramide metabolic process GO:0006672 64 33 0,000 0,15385214 0,17652277 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,15385214 0,17643863 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,15385214 0,17635457 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,15385214 0,17627059 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,15385214 0,17618669 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,15812732 0,18099635 ! glial cell differentiation GO:0010001 63 34 0,000 0,15812732 0,18091028 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,15812732 0,1808243 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,15812732 0,1807384 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,15812732 0,18065257 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,15812732 0,18056684 ! mismatch repair GO:0006298 46 34 0,000 0,15812732 0,18048118 ! spermatid development GO:0007286 63 34 0,000 0,15812732 0,1803956 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,15812732 0,18031011 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,15812732 0,18022469 ! regulation of muscle development GO:0048634 70 35 0,000 0,16238104 0,18498521 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,16238104 0,18489767 ! negative regulation of secretion GO:0051048 63 35 0,000 0,16238104 0,1848102 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,16238104 0,18472282 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,16238104 0,18463553 ! odontogenesis GO:0042476 66 35 0,000 0,16238104 0,18454831 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,16238104 0,18446118 ! female gonad development GO:0008585 58 35 0,000 0,16238104 0,18437413 ! telencephalon development GO:0021537 68 35 0,000 0,16238104 0,18428716 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,16238104 0,18420027 ! cytokine production GO:0001816 59 35 0,000 0,16238104 0,18411346 ! neural tube formation GO:0001841 67 35 0,000 0,16238104 0,18402674 ! vesicle localization GO:0051648 64 35 0,000 0,16238104 0,1839401 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,1666134 0,18864558 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,1666134 0,18855684 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,1666134 0,18846819 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,1666134 0,18837963 ! cell junction organization GO:0034330 86 36 0,000 0,1666134 0,18829115 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,1666134 0,18820275 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,1666134 0,18811443 ! positive regulation of cell development GO:0010720 80 36 0,000 0,1666134 0,1880262 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,1666134 0,18793804 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,1666134 0,18784998 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,1666134 0,18776199 ! aerobic respiration GO:0009060 55 36 0,000 0,1666134 0,18767409 ! embryonic organ development GO:0048568 57 36 0,000 0,1666134 0,18758627 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,1666134 0,18749853 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,1666134 0,18741087 ! RNA export from nucleus GO:0006405 56 37 0,000 0,17082453 0,19205785 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,17082453 0,19196815 ! meiosis I GO:0007127 65 37 0,000 0,17082453 0,19187853 ! sister chromatid segregation GO:0000819 58 37 0,000 0,17082453 0,19178899 ! organic anion transport GO:0015711 68 37 0,000 0,17082453 0,19169954 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,17082453 0,19161017 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,17082453 0,19152088 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,17082453 0,19143168 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,17082453 0,19134256 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,17082453 0,19125352 ! spermatid differentiation GO:0048515 66 37 0,000 0,17082453 0,19116456 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,17501451 0,19576239 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,17501451 0,19567142 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,17501451 0,19558054 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,17501451 0,19548974 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,17501451 0,19539903 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,17501451 0,1953084 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,17501451 0,19521785 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,17501451 0,19512739 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,17501451 0,19503701 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,17501451 0,19494672 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,17501451 0,1948565 ! mRNA catabolic process GO:0006402 71 39 0,000 0,17918346 0,19940583 ! learning GO:0007612 77 39 0,000 0,17918346 0,19931364 ! ear morphogenesis GO:0042471 60 39 0,000 0,17918346 0,19922153 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,17918346 0,19912951 ! ion transmembrane transport GO:0034220 66 39 0,000 0,17918346 0,19903758 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,17918346 0,19894573 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,17918346 0,19885396 ! RNA modification GO:0009451 57 39 0,000 0,17918346 0,19876228 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,17918346 0,19867069 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,18333148 0,2031762 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,18333148 0,20308266 ! feeding behavior GO:0007631 59 40 0,000 0,18333148 0,2029892 ! negative regulation of binding GO:0051100 72 40 0,000 0,18333148 0,20289583 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,18333148 0,20280254 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,18333148 0,20270934 ! maintenance of protein location GO:0045185 91 40 0,000 0,18333148 0,20261623 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,18745867 0,20708244 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,18745867 0,20698741 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,18745867 0,20689246 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,18745867 0,2067976 ! gliogenesis GO:0042063 88 41 0,000 0,18745867 0,20670282 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,18745867 0,20660813 ! female gamete generation GO:0007292 61 41 0,000 0,18745867 0,20651353 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,18745867 0,20641902 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,19156514 0,21084434 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,19156514 0,21074793 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,19156514 0,21065161 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,19156514 0,21055538 ! neuron migration GO:0001764 79 42 0,000 0,19156514 0,21045924 ! regulation of protein secretion GO:0050708 71 42 0,000 0,19156514 0,21036318 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,19156514 0,21026721 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,195651 0,21465404 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,195651 0,2145562 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,195651 0,21445845 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,195651 0,21436079 ! neural tube development GO:0021915 77 43 0,000 0,195651 0,21426322 ! striated muscle contraction GO:0006941 77 43 0,000 0,195651 0,21416574 ! phagocytosis GO:0006909 90 43 0,000 0,195651 0,21406835 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,195651 0,21397105 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,19971634 0,21831781 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,19971634 0,21821867 ! double-strand break repair GO:0006302 81 44 0,000 0,19971634 0,21811961 ! biopolymer methylation GO:0043414 84 44 0,000 0,19971634 0,21802065 ! B cell differentiation GO:0030183 107 44 0,000 0,19971634 0,21792177 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,19971634 0,21782299 ! maintenance of location in cell GO:0051651 97 44 0,000 0,19971634 0,21772429 ! glycolysis GO:0006096 65 45 0,000 0,20376127 0,22203334 ! leukocyte migration GO:0050900 68 45 0,000 0,20376127 0,22193282 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,20376127 0,2218324 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,20376127 0,22173207 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,20376127 0,22163183 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,20376127 0,22153168 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,20376127 0,22143162 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,20376127 0,22133165 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,20376127 0,22123177 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,20778588 0,2254997 ! pigmentation GO:0043473 100 46 0,000 0,20778588 0,22539803 ! positive regulation of defense response GO:0031349 76 47 0,000 0,21179029 0,22963832 ! response to calcium ion GO:0051592 81 47 0,000 0,21179029 0,22953488 ! endosome transport GO:0016197 108 47 0,000 0,21179029 0,22943154 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,21179029 0,22932828 ! methylation GO:0032259 90 47 0,000 0,21179029 0,22922512 ! mitochondrial transport GO:0006839 82 48 0,000 0,21577459 0,2334324 ! Notch signaling pathway GO:0007219 96 48 0,000 0,21577459 0,23332749 ! cellular component disassembly GO:0022411 86 48 0,000 0,21577459 0,23322267 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,21577459 0,23311794 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,21577459 0,23301331 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,21577459 0,23290878 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,21973888 0,2370815 ! regulation of action potential GO:0001508 95 49 0,000 0,21973888 0,23697523 ! regulation of ion transport GO:0043269 77 49 0,000 0,21973888 0,23686906 ! peptide metabolic process GO:0006518 76 49 0,000 0,21973888 0,23676299 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,21973888 0,236657 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,21973888 0,23655112 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,21973888 0,23644533 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,21973888 0,23633963 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,21973888 0,23623402 ! inner ear development GO:0048839 79 50 0,000 0,22368326 0,2403671 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,22368326 0,24025979 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,22368326 0,24015258 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,22760784 0,24425712 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,22760784 0,24414822 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,22760784 0,24403942 ! excretion GO:0007588 83 51 0,000 0,22760784 0,24393071 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,22760784 0,24382211 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,22760784 0,2437136 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,22760784 0,24360518 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,22760784 0,24349687 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,2315127 0,24756425 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,2315127 0,24745427 ! amino acid activation GO:0043038 92 52 0,000 0,2315127 0,24734438 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,2315127 0,2472346 ! synapse organization GO:0050808 85 52 0,000 0,2315127 0,24712491 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,23539795 0,25116074 ! RNA catabolic process GO:0006401 93 53 0,000 0,23539795 0,25104941 ! regulation of translational initiation GO:0006446 82 53 0,000 0,23539795 0,25093818 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,23539795 0,25082705 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,23539795 0,25071601 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,23539795 0,25060507 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,23926369 0,25460789 ! cell recognition GO:0008037 85 54 0,000 0,23926369 0,25449533 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,23926369 0,25438287 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,23926369 0,25427051 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,23926369 0,25415825 ! chloride transport GO:0006821 90 55 0,000 0,24311001 0,25813004 ! glucose catabolic process GO:0006007 82 55 0,000 0,24311001 0,25801618 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,24311001 0,25790242 ! aging GO:0007568 103 55 0,000 0,24311001 0,25778875 ! RNA elongation GO:0006354 79 55 0,000 0,24311001 0,25767519 ! nuclear export GO:0051168 97 55 0,000 0,24311001 0,25756172 ! sensory perception of smell GO:0007608 80 56 0,000 0,24693701 0,26150107 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,24693701 0,26138603 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,24693701 0,26127108 ! proton transport GO:0015992 94 56 0,000 0,24693701 0,26115624 ! hydrogen transport GO:0006818 97 58 0,000 0,25453343 0,26907181 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,25830305 0,27293682 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,25830305 0,27281701 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,25830305 0,2726973 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,25830305 0,27257769 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,26205373 0,27641441 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,26205373 0,27629328 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,26205373 0,27617226 ! regulation of heart contraction GO:0008016 110 60 0,000 0,26205373 0,27605135 ! camera-type eye development GO:0043010 116 60 0,000 0,26205373 0,27593054 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,26578557 0,27973757 ! tRNA processing GO:0008033 89 61 0,000 0,26578557 0,27961525 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,26578557 0,27949304 ! ear development GO:0043583 103 62 0,000 0,26949866 0,28327382 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,26949866 0,28315012 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,26949866 0,28302652 ! regulation of mitosis GO:0007088 105 63 0,000 0,27319309 0,28678123 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,27319309 0,28665616 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,27686896 0,29038654 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,27686896 0,29026001 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,27686896 0,29013359 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,27686896 0,29000728 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,28052636 0,29371037 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,28052636 0,29358262 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,28052636 0,29345497 GO:0035113|embryonic appendage morphogenesis, ! actin filament organization GO:0007015 148 66 0,000 0,28416539 0,29713252 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,28416539 0,29700344 ! extracellular matrix organization GO:0030198 133 66 0,000 0,28416539 0,29687448 ! secondary metabolic process GO:0019748 116 66 0,000 0,28416539 0,29674563 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,28778613 0,30039628 ! chromosome segregation GO:0007059 113 67 0,000 0,28778613 0,30026601 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,28778613 0,30013586 ! hexose catabolic process GO:0019320 104 67 0,000 0,28778613 0,30000582 ! adaptive immune response GO:0002250 119 67 0,000 0,28778613 0,29987589 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,28778613 0,29974607 ! amino acid transport GO:0006865 125 68 0,000 0,29138868 0,30336701 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,29138868 0,30323579 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,29138868 0,30310469 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,29138868 0,30297371 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,29138868 0,30284283 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,29497312 0,3064358 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,29497312 0,30630355 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,29497312 0,30617141 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,29497312 0,30603938 ! appendage morphogenesis GO:0035107 135 70 0,000 0,29853955 0,3096061 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 0,000 0,30208806 0,31315117 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,30208806 0,31301631 ! B cell activation GO:0042113 160 71 0,000 0,30208806 0,31288156 ! acute inflammatory response GO:0002526 113 72 0,000 0,30561873 0,31640218 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,30561873 0,31626609 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,30561873 0,31613012 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,30561873 0,31599427 ! learning or memory GO:0007611 147 73 0,000 0,30913166 0,31948916 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,30913166 0,31935198 ! axon guidance GO:0007411 139 73 0,000 0,30913166 0,31921492 ! fertilization GO:0009566 90 73 0,000 0,30913166 0,31907798 ! transition metal ion transport GO:0000041 126 74 0,000 0,31262693 0,32254734 ! neurotransmitter transport GO:0006836 123 74 0,000 0,31262693 0,32240909 ! meiosis GO:0007126 121 74 0,000 0,31262693 0,32227095 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,31262693 0,32213293 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,31262693 0,32199503 ! eye development GO:0001654 143 74 0,000 0,31262693 0,32185725 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,31610464 0,32529844 ! meiotic cell cycle GO:0051321 122 75 0,000 0,31610464 0,32515937 ! rhythmic process GO:0048511 128 75 0,000 0,31610464 0,32502041 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,31956486 0,32843787 ! defense response to bacterium GO:0042742 89 76 0,000 0,31956486 0,32829763 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,31956486 0,32815752 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,32300769 0,33155141 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,32300769 0,33141003 ! blood coagulation GO:0007596 146 78 0,000 0,32643322 0,3347819 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,32643322 0,33463926 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,32643322 0,33449673 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,32984153 0,33784535 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,32984153 0,33770158 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,32984153 0,33755794 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,3332327 0,34088345 ! response to metal ion GO:0010038 140 80 0,000 0,3332327 0,34073858 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,3332327 0,34059383 ! digestion GO:0007586 112 81 0,000 0,33660683 0,3438964 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,33660683 0,34375044 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,33660683 0,3436046 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,33996399 0,34688438 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,33996399 0,34673733 ! response to drug GO:0042493 143 82 0,000 0,33996399 0,34659041 ! response to nutrient GO:0007584 125 82 0,000 0,33996399 0,34644361 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,33996399 0,34629694 ! regulation of lyase activity GO:0051339 160 83 0,000 0,34330428 0,34955146 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,34662777 0,35278613 ! hemostasis GO:0007599 158 84 0,000 0,34662777 0,35263696 ! regulation of ligase activity GO:0051340 142 84 0,000 0,34662777 0,35248792 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,34662777 0,352339 ! response to unfolded protein GO:0006986 131 85 0,000 0,34993455 0,35555006 ! nucleosome assembly GO:0006334 122 85 0,000 0,34993455 0,35539997 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,34993455 0,35525001 ! amine biosynthetic process GO:0009309 138 86 0,000 0,35322471 0,35843891 ! response to inorganic substance GO:0010035 153 86 0,000 0,35322471 0,35828779 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,35322471 0,35813681 ! chromatin assembly GO:0031497 124 86 0,000 0,35322471 0,35798595 ! alcohol catabolic process GO:0046164 130 86 0,000 0,35322471 0,35783522 ! amine transport GO:0015837 155 86 0,000 0,35322471 0,35768462 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,35649832 0,36084769 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,35975547 0,36399145 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,35975547 0,36383845 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,35975547 0,36368557 ! cellular defense response GO:0006968 114 89 0,000 0,36299624 0,36680763 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,36299624 0,36665364 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,36622072 0,36975537 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,36622072 0,36960027 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,36622072 0,36944531 ! sterol metabolic process GO:0016125 152 91 0,000 0,36942898 0,37252562 ! response to protein stimulus GO:0051789 149 91 0,000 0,36942898 0,37236956 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,36942898 0,37221362 ! nucleosome organization GO:0034728 138 92 0,000 0,37262111 0,37527266 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,37262111 0,37511564 ! vitamin metabolic process GO:0006766 139 92 0,000 0,37262111 0,37495876 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,37579718 0,37799666 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,37579718 0,3778387 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,37895728 0,38085682 ! female pregnancy GO:0007565 164 94 0,000 0,37895728 0,38069779 ! transcription initiation GO:0006352 153 94 0,000 0,37895728 0,3805389 ! forebrain development GO:0030900 188 95 0,000 0,38210149 0,38353616 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,38210149 0,38337622 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,38522988 0,38635393 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,38522988 0,38619295 ! positive regulation of immune response GO:0050778 156 96 0,000 0,38522988 0,38603211 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,38834253 0,38898923 ! hormone metabolic process GO:0042445 157 97 0,000 0,38834253 0,38882736 ! response to virus GO:0009615 160 98 0,000 0,39143953 0,39176519 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,39143953 0,39160229 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,39452096 0,39452096