pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1154-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 12 6 3,000 5,093E-09 1,225E-05 ! auditory receptor cell differentiation GO:0042491 32 16 4,000 6,06E-09 7,291E-06 ! regulation of lipid kinase activity GO:0043550 13 7 3,000 1,184E-08 9,499E-06 ! inner ear receptor cell differentiation GO:0060113 37 20 4,000 2,121E-08 1,276E-05 ! establishment of nucleus localization GO:0040023 16 8 3,000 2,361E-08 1,136E-05 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 4,000 2,775E-08 1,113E-05 ! mechanoreceptor differentiation GO:0042490 40 22 4,000 3,578E-08 1,23E-05 ! nucleus localization GO:0051647 19 11 3,000 1,102E-07 3,314E-05 ! cellular response to extracellular stimulus GO:0031668 48 29 4,000 1,575E-07 4,209E-05 ! leukocyte differentiation GO:0002521 202 96 6,000 2,166E-07 5,211E-05 ! lung development GO:0030324 144 67 5,000 4,846E-07 1,06E-04 ! respiratory tube development GO:0030323 150 70 5,000 6,299E-07 1,263E-04 ! respiratory system development GO:0060541 153 72 5,000 7,453E-07 1,379E-04 ! protein oligomerization GO:0051259 139 78 5,000 1,199E-06 2,061E-04 ! cellular response to starvation GO:0009267 33 20 3,000 1,569E-06 2,517E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 1,593E-06 2,396E-04 GO:0031272|regulation of pseudopodium assembly, ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 1,713E-06 2,424E-04 ! inner ear development GO:0048839 79 50 4,000 2,611E-06 3,49E-04 ! macrophage differentiation GO:0030225 11 7 2,000 2,779E-06 3,519E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 3,82E-06 4,596E-04 ! response to starvation GO:0042594 42 25 3,000 4,029E-06 4,616E-04 ! cellular response to nutrient levels GO:0031669 41 25 3,000 4,029E-06 4,406E-04 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 4,313E-06 4,512E-04 ! interphase GO:0051325 213 98 5,000 4,578E-06 4,59E-04 ! autophagic vacuole formation GO:0000045 15 9 2,000 6,628E-06 6,379E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 6,628E-06 6,133E-04 ! negative regulation of protein complex assembly GO:0031333 59 29 3,000 7,463E-06 6,65E-04 ! ear development GO:0043583 103 62 4,000 7,649E-06 6,572E-04 ! regulation of lipid metabolic process GO:0019216 115 63 4,000 8,279E-06 6,869E-04 ! macroautophagy GO:0016236 17 10 2,000 9,438E-06 7,569E-04 ! regulation of embryonic development GO:0045995 27 11 2,000 1,294E-05 1,004E-03 ! cell cycle checkpoint GO:0000075 137 69 4,000 1,296E-05 9,747E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 1,719E-05 1,254E-03 ! lymphocyte differentiation GO:0030098 167 75 4,000 1,95E-05 1,38E-03 ! detection of bacterium GO:0016045 18 15 2,000 3,522E-05 2,421E-03 ! B cell differentiation GO:0030183 107 44 3,000 4,055E-05 2,71E-03 ! filopodium assembly GO:0046847 32 16 2,000 4,321E-05 2,81E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 4,436E-05 2,809E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 5,23E-05 3,227E-03 ! microspike assembly GO:0030035 36 17 2,000 5,23E-05 3,146E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 5,516E-05 3,237E-03 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 3,000 7,292E-05 4,177E-03 ! G1 phase GO:0051318 40 19 2,000 7,406E-05 4,144E-03 ! Golgi vesicle transport GO:0048193 207 99 4,000 7,434E-05 4,065E-03 ! response to UV GO:0009411 104 53 3,000 8,487E-05 4,538E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 8,685E-05 4,543E-03 ! RNA elongation GO:0006354 79 55 3,000 9,818E-05 5,026E-03 ! detection of biotic stimulus GO:0009595 29 21 2,000 1,01E-04 5,063E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 1,054E-04 5,174E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 1,166E-04 5,61E-03 ! establishment of organelle localization GO:0051656 109 59 3,000 1,293E-04 6,099E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 1,336E-04 6,184E-03 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 1,38E-04 6,267E-03 ! regulation of protein complex assembly GO:0043254 117 61 3,000 1,472E-04 6,56E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 1,522E-04 6,66E-03 ! protein tetramerization GO:0051262 52 24 2,000 1,522E-04 6,541E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 1,725E-04 7,28E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 1,725E-04 7,154E-03 ! negative regulation of cell development GO:0010721 73 25 2,000 1,725E-04 7,033E-03 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 2,000 1,725E-04 6,916E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 1,862E-04 7,343E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,862E-04 7,224E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,862E-04 7,109E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 1,862E-04 6,998E-03 ! valine metabolic process GO:0006573 10 5 1,000 1,862E-04 6,891E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,862E-04 6,786E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 1,862E-04 6,685E-03 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 1,862E-04 6,587E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! glial cell migration GO:0008347 11 5 1,000 1,862E-04 6,491E-03 ! myeloid cell differentiation GO:0030099 111 65 3,000 1,885E-04 6,478E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 1,943E-04 6,586E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 1,943E-04 6,494E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 2,119E-04 6,985E-03 ! activation of MAPK activity GO:0000187 115 67 3,000 2,119E-04 6,891E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 2,179E-04 6,991E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 2,179E-04 6,899E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 2,179E-04 6,81E-03 ! autophagy GO:0006914 41 27 2,000 2,179E-04 6,723E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 2,374E-04 7,232E-03 ! positive regulation of T cell differentiation GO:0045582 42 28 2,000 2,433E-04 7,318E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 2,433E-04 7,227E-03 ! B cell activation GO:0042113 160 71 3,000 2,651E-04 7,778E-03 ! positive regulation of DNA repair GO:0045739 9 6 1,000 2,784E-04 8,071E-03 ! male sex determination GO:0030238 15 6 1,000 2,784E-04 7,975E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 2,784E-04 7,881E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 2,784E-04 7,79E-03 GO:0045686|negative regulation of glial cell differentiation, ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 2,784E-04 7,7E-03 ! nucleoside catabolic process GO:0009164 7 6 1,000 2,784E-04 7,613E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2,784E-04 7,527E-03 ! regulation of caspase activity GO:0043281 122 72 3,000 2,797E-04 7,478E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 3,108E-04 8,217E-03 ! organelle localization GO:0051640 136 74 3,000 3,108E-04 8,128E-03 ! steroid biosynthetic process GO:0006694 131 76 3,000 3,442E-04 8,905E-03 ! positive regulation of lymphocyte activation GO:0051251 127 77 3,000 3,619E-04 9,262E-03 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 2,000 3,637E-04 9,212E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 3,000 3,801E-04 9,527E-03 ! positive regulation of protein ubiquitination GO:0031398 12 7 1,000 3,887E-04 9,641E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 3,887E-04 9,543E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 3,887E-04 9,447E-03 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 3,887E-04 9,352E-03 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 1,000 3,887E-04 9,26E-03 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 1,000 3,887E-04 9,169E-03 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 3,887E-04 9,08E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 3,887E-04 8,993E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 3,887E-04 8,907E-03 ! response to tumor cell GO:0002347 13 7 1,000 3,887E-04 8,823E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 3,887E-04 8,74E-03 ! axonal fasciculation GO:0007413 18 7 1,000 3,887E-04 8,659E-03 ! lymph node development GO:0048535 10 7 1,000 3,887E-04 8,58E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 3,887E-04 8,502E-03 ! DNA damage checkpoint GO:0000077 71 33 2,000 3,988E-04 8,645E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 3,991E-04 8,573E-03 ! protein import into nucleus GO:0006606 158 80 3,000 4,187E-04 8,915E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 4,361E-04 9,203E-03 ! nuclear import GO:0051170 161 81 3,000 4,39E-04 9,184E-03 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 4,599E-04 9,539E-03 ! negative regulation of growth GO:0045926 155 84 3,000 5,04E-04 0,01036404 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 5,168E-04 0,01053735 ! succinate metabolic process GO:0006105 14 8 1,000 5,168E-04 0,0104488 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 5,168E-04 0,01036173 ! glycine catabolic process GO:0006546 13 8 1,000 5,168E-04 0,0102761 ! ER overload response GO:0006983 12 8 1,000 5,168E-04 0,01019187 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 5,168E-04 0,01010901 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 5,168E-04 0,01002748 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 5,168E-04 9,947E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 5,168E-04 9,868E-03 ! mast cell activation GO:0045576 14 8 1,000 5,168E-04 9,791E-03 ! DNA integrity checkpoint GO:0031570 75 36 2,000 5,17E-04 9,718E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 5,17E-04 9,643E-03 ! positive regulation of cell activation GO:0050867 145 85 3,000 5,271E-04 9,756E-03 GO:0002696|positive regulation of leukocyte activation, ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 5,608E-04 0,01030047 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 5,608E-04 0,01022244 ! protein localization in nucleus GO:0034504 176 87 3,000 5,756E-04 0,01041266 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 6,07E-04 0,01089837 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 6,07E-04 0,01081764 ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 6,07E-04 0,0107381 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of developmental growth GO:0048638 15 9 1,000 6,626E-04 0,01163585 ! axon extension GO:0048675 15 9 1,000 6,626E-04 0,01155153 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 6,626E-04 0,01146842 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 6,626E-04 0,01138651 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 21 9 1,000 6,626E-04 0,01130575 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 1,000 6,626E-04 0,01122613 ! phosphagen metabolic process GO:0006599 12 9 1,000 6,626E-04 0,01114763 GO:0006600|creatine metabolic process, ! protein heterooligomerization GO:0051291 16 9 1,000 6,626E-04 0,01107021 ! postreplication repair GO:0006301 22 9 1,000 6,626E-04 0,01099387 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 6,626E-04 0,01091857 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 6,626E-04 0,01084429 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage differentiation GO:0045649 15 9 1,000 6,626E-04 0,01077102 ! serine family amino acid catabolic process GO:0009071 16 9 1,000 6,626E-04 0,01069873 ! T cell differentiation GO:0030217 81 41 2,000 7,597E-04 0,01218608 ! regulation of T cell differentiation GO:0045580 70 41 2,000 7,597E-04 0,01210538 ! transcription initiation GO:0006352 153 94 3,000 7,703E-04 0,01219339 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 8,258E-04 0,01298668 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 8,258E-04 0,01290235 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 8,258E-04 0,01281911 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 8,258E-04 0,01273693 ! endoderm development GO:0007492 16 10 1,000 8,258E-04 0,0126558 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 8,258E-04 0,0125757 ! regulation of gliogenesis GO:0014013 23 10 1,000 8,258E-04 0,01249661 GO:0045685|regulation of glial cell differentiation, ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 8,258E-04 0,01241851 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of immune effector process GO:0002698 20 10 1,000 8,258E-04 0,01234138 ! localization within membrane GO:0051668 20 10 1,000 8,258E-04 0,01226519 ! double-strand break repair GO:0006302 81 44 2,000 9,35E-04 0,01380068 ! cell cycle arrest GO:0007050 213 100 3,000 9,709E-04 0,01424321 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,006E-03 0,01467631 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,006E-03 0,0145879 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,006E-03 0,01450055 ! neuroblast proliferation GO:0007405 24 11 1,000 1,006E-03 0,01441424 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 1,065E-03 0,01516012 ! response to insulin stimulus GO:0032868 95 46 2,000 1,065E-03 0,01507094 ! protein homooligomerization GO:0051260 76 47 2,000 1,134E-03 0,01595376 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,204E-03 0,01684672 ! virus-host interaction GO:0019048 29 12 1,000 1,204E-03 0,01674934 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,204E-03 0,01665308 ! hippocampus development GO:0021766 26 12 1,000 1,204E-03 0,01655792 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,204E-03 0,01646384 ! entry into host cell GO:0030260 32 12 1,000 1,204E-03 0,01637083 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 1,204E-03 0,01627886 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,204E-03 0,01618791 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,206E-03 0,01611537 ! activation of caspase activity GO:0006919 84 48 2,000 1,206E-03 0,01602634 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 1,206E-03 0,01593828 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 1,206E-03 0,01585118 ! regulation of cell projection organization GO:0031344 121 50 2,000 1,358E-03 0,01775236 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 1,419E-03 0,01845802 GO:0000725|recombinational repair, ! response to X-ray GO:0010165 25 13 1,000 1,419E-03 0,01835878 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,419E-03 0,0182606 ! regulation of DNA repair GO:0006282 21 13 1,000 1,419E-03 0,01816347 ! regulation of cellular pH GO:0030641 22 13 1,000 1,419E-03 0,01806737 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,419E-03 0,01797228 ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 1,419E-03 0,01787818 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,419E-03 0,01778507 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! vesicle organization GO:0016050 107 51 2,000 1,438E-03 0,0179255 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 1,438E-03 0,0178331 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 2,000 1,521E-03 0,0187684 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,651E-03 0,02026796 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 1,000 1,651E-03 0,02016508 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 1,651E-03 0,02006323 ! response to gamma radiation GO:0010332 28 14 1,000 1,651E-03 0,01996241 ! regulation of RNA stability GO:0043487 32 14 1,000 1,651E-03 0,0198626 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,651E-03 0,01976378 ! negative regulation of cytoskeleton organization GO:0051494 124 54 2,000 1,696E-03 0,02020658 ! positive regulation of caspase activity GO:0043280 95 55 2,000 1,789E-03 0,02119993 GO:0010952|positive regulation of peptidase activity, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 1,000 1,9E-03 0,0224051 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,9E-03 0,0222958 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,9E-03 0,02218757 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 1,9E-03 0,02208039 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 1,982E-03 0,02293057 ! positive regulation of cell migration GO:0030335 126 57 2,000 1,982E-03 0,02282085 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 2,165E-03 0,02480351 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,165E-03 0,02468595 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 2,165E-03 0,02456951 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 2,165E-03 0,02445416 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 2,165E-03 0,02433989 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 2,165E-03 0,02422668 ! negative regulation of immune response GO:0050777 35 16 1,000 2,165E-03 0,02411452 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,165E-03 0,02400339 ! neuron recognition GO:0008038 35 16 1,000 2,165E-03 0,02389329 ! negative regulation of inflammatory response GO:0050728 22 16 1,000 2,165E-03 0,02378418 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,165E-03 0,02367607 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 2,297E-03 0,02500204 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 2,297E-03 0,02488942 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 2,408E-03 0,02597725 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,447E-03 0,02627882 ! limbic system development GO:0021761 36 17 1,000 2,447E-03 0,02616202 ! glycine metabolic process GO:0006544 28 17 1,000 2,447E-03 0,02604626 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 2,447E-03 0,02593152 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 2,447E-03 0,02581779 ! viral reproductive process GO:0022415 126 62 2,000 2,522E-03 0,02649909 ! detection of external stimulus GO:0009581 91 63 2,000 2,64E-03 0,02761576 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 2,64E-03 0,02749621 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 2,745E-03 0,02846313 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,745E-03 0,02834097 ! centrosome cycle GO:0007098 25 18 1,000 2,745E-03 0,02821985 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 2,745E-03 0,02809977 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 2,745E-03 0,0279807 ! positive regulation of cell motion GO:0051272 146 64 2,000 2,761E-03 0,02802953 ! cell projection assembly GO:0030031 120 66 2,000 3,013E-03 0,03046293 ! negative regulation of defense response GO:0031348 25 19 1,000 3,059E-03 0,0307923 ! lipid phosphorylation GO:0046834 35 19 1,000 3,059E-03 0,030664 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 3,059E-03 0,03053676 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 3,145E-03 0,03126499 ! homeostasis of number of cells GO:0048872 114 67 2,000 3,145E-03 0,03113633 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 3,145E-03 0,03100872 ! positive regulation of T cell activation GO:0050870 109 67 2,000 3,145E-03 0,03088215 ! negative regulation of kinase activity GO:0033673 131 68 2,000 3,279E-03 0,03207484 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 3,279E-03 0,03194498 ! viral reproduction GO:0016032 134 68 2,000 3,279E-03 0,03181617 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,389E-03 0,03274637 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 3,389E-03 0,03261539 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 3,389E-03 0,03248545 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 3,389E-03 0,03235654 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 3,389E-03 0,03222864 ! sensory perception of pain GO:0019233 30 20 1,000 3,389E-03 0,03210176 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 3,389E-03 0,03197587 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 1,000 3,389E-03 0,03185096 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 3,389E-03 0,03172703 ! regulation of cell killing GO:0031341 42 21 1,000 3,735E-03 0,03483165 ! cell aging GO:0007569 44 21 1,000 3,735E-03 0,03469717 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 3,735E-03 0,03456371 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 3,735E-03 0,03443129 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 3,735E-03 0,03429987 ! DNA modification GO:0006304 34 21 1,000 3,735E-03 0,03416945 ! negative regulation of transferase activity GO:0051348 140 72 2,000 3,854E-03 0,03512216 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 4,097E-03 0,03719688 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 4,097E-03 0,03705704 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 4,097E-03 0,03691825 ! deoxyribonucleotide metabolic process GO:0009262 32 22 1,000 4,097E-03 0,0367805 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 4,097E-03 0,03664377 ! positive regulation of B cell activation GO:0050871 38 22 1,000 4,097E-03 0,03650805 ! positive regulation of DNA replication GO:0045740 43 23 1,000 4,474E-03 0,03972446 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 4,474E-03 0,03957841 ! regulation of DNA recombination GO:0000018 48 23 1,000 4,474E-03 0,03943344 ! purine ribonucleoside metabolic process GO:0046128 34 23 1,000 4,474E-03 0,03928952 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 1,000 4,474E-03 0,03914665 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 1,000 4,474E-03 0,03900481 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 4,474E-03 0,038864 ! negative regulation of organelle organization GO:0010639 161 78 2,000 4,824E-03 0,04174892 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,867E-03 0,04197381 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 4,867E-03 0,0418239 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 4,867E-03 0,04167506 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 4,867E-03 0,04152728 ! pallium development GO:0021543 49 24 1,000 4,867E-03 0,04138054 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 4,867E-03 0,04123483 ! activation of protein kinase activity GO:0032147 147 79 2,000 4,999E-03 0,04219803 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 4,999E-03 0,04205048 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 5,276E-03 0,04422624 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 5,276E-03 0,04407268 ! protein amino acid alkylation GO:0008213 53 25 1,000 5,276E-03 0,04392018 GO:0006479|protein amino acid methylation, ! negative regulation of DNA replication GO:0008156 42 25 1,000 5,276E-03 0,04376873 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 5,276E-03 0,04361832 ! somitogenesis GO:0001756 43 25 1,000 5,276E-03 0,04346894 ! liver development GO:0001889 53 25 1,000 5,276E-03 0,04332059 ! T cell activation GO:0042110 168 81 2,000 5,359E-03 0,04385782 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 5,359E-03 0,04370915 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 5,699E-03 0,04632335 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 5,699E-03 0,04616738 ! initiation of viral infection GO:0019059 57 26 1,000 5,699E-03 0,04601245 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 5,699E-03 0,04585857 ! microtubule organizing center organization GO:0031023 39 26 1,000 5,699E-03 0,0457057 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 5,699E-03 0,04555386 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 5,699E-03 0,04540302 ! positive regulation of nuclear division GO:0051785 40 26 1,000 5,699E-03 0,04525317 GO:0045840|positive regulation of mitosis, ! protein amino acid acylation GO:0043543 55 27 1,000 6,137E-03 0,04857467 ! mitochondrial membrane organization GO:0007006 57 27 1,000 6,137E-03 0,04841541 ! base-excision repair GO:0006284 41 27 1,000 6,137E-03 0,04825719 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 6,137E-03 0,0481 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 6,137E-03 0,04794383 ! nitrogen compound catabolic process GO:0044270 143 87 2,000 6,533E-03 0,05087217 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 6,591E-03 0,05115345 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 1,000 6,591E-03 0,05098896 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 6,591E-03 0,05082554 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 6,591E-03 0,05066316 ! positive regulation of protein modification process GO:0031401 136 88 2,000 6,743E-03 0,05166647 ! regulation of pH GO:0006885 43 29 1,000 7,059E-03 0,05391742 ! respiratory gaseous exchange GO:0007585 57 29 1,000 7,059E-03 0,0537468 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 7,059E-03 0,05357725 ! regulation of cell cycle process GO:0010564 149 90 2,000 7,173E-03 0,05427488 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 7,542E-03 0,05688287 ! regulation of B cell activation GO:0050864 50 30 1,000 7,542E-03 0,05670511 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 8,039E-03 0,06025604 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 8,039E-03 0,06006891 ! erythrocyte differentiation GO:0030218 55 31 1,000 8,039E-03 0,05988294 ! serine family amino acid metabolic process GO:0009069 49 31 1,000 8,039E-03 0,05969811 ! myeloid leukocyte activation GO:0002274 49 31 1,000 8,039E-03 0,05951443 ! regulation of T cell activation GO:0050863 158 94 2,000 8,083E-03 0,05965416 ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 8,551E-03 0,06291537 ! response to ionizing radiation GO:0010212 65 32 1,000 8,551E-03 0,06272355 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 8,551E-03 0,0625329 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 1,000 8,551E-03 0,06234341 ! positive regulation of catabolic process GO:0009896 64 32 1,000 8,551E-03 0,06215506 ! detection of stimulus GO:0051606 151 96 2,000 8,562E-03 0,06204695 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 9,077E-03 0,06558176 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 9,617E-03 0,06927567 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 9,617E-03 0,06906888 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 1,000 9,617E-03 0,06886332 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01017085 0,07261441 ! telencephalon development GO:0021537 68 35 1,000 0,01017085 0,07239958 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01017085 0,07218601 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01017085 0,0719737 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01017085 0,07176263 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01073872 0,07554784 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01132031 0,07940722 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,0119155 0,08333922 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,0119155 0,08309766 ! mRNA catabolic process GO:0006402 71 39 1,000 0,01252415 0,0870899 ! segmentation GO:0035282 67 39 1,000 0,01252415 0,08683892 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,01252415 0,08658938 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,01314614 0,09062925 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,01314614 0,09037031 ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,01314614 0,09011284 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,01378134 0,09419858 ! gliogenesis GO:0042063 88 41 1,000 0,01378134 0,09393173 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,01378134 0,09366638 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,01378134 0,09340253 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01442963 0,09752157 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01442963 0,0972484 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01442963 0,09697676 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,01442963 0,09670663 ! neuron migration GO:0001764 79 42 1,000 0,01442963 0,096438 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,01442963 0,09617086 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,01509088 0,10030014 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,01509088 0,10002383 ! biopolymer methylation GO:0043414 84 44 1,000 0,01576497 0,10420471 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,01576497 0,10391922 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,01576497 0,10363528 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,01645178 0,10785552 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,01645178 0,10756244 ! cell growth GO:0016049 84 45 1,000 0,01645178 0,10727094 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,01715118 0,11152904 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,01715118 0,11122842 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01715118 0,11092942 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01786306 0,11522394 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,01786306 0,11491585 ! methylation GO:0032259 90 47 1,000 0,01786306 0,11460941 ! mitochondrial transport GO:0006839 82 48 1,000 0,0185873 0,11893894 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,0185873 0,11862345 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,01932377 0,12299733 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,01932377 0,1226728 ! histone modification GO:0016570 91 50 1,000 0,02007236 0,12708973 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,02007236 0,12675617 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,02007236 0,12642434 ! viral infectious cycle GO:0019058 99 51 1,000 0,02083295 0,13087227 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,02083295 0,13053145 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,02083295 0,13019241 ! positive regulation of binding GO:0051099 78 51 1,000 0,02083295 0,12985512 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,02083295 0,12951958 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02156156 0,13370387 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02156156 0,13336016 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02156156 0,13301821 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02156156 0,13267801 ! neuron fate determination GO:0048664 7 5 0,000 0,02156156 0,13233955 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02156156 0,13200281 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02156156 0,13166777 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02156156 0,13133444 ! polyol transport GO:0015791 12 5 0,000 0,02156156 0,13100278 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02156156 0,1306728 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02156156 0,13034448 ! response to superoxide GO:0000303 10 5 0,000 0,02156156 0,1300178 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02156156 0,12969276 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02156156 0,12936933 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02156156 0,12904752 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02156156 0,1287273 ! female meiosis GO:0007143 7 5 0,000 0,02156156 0,12840867 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02156156 0,12809161 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02156156 0,12777612 ! cobalt ion transport GO:0006824 11 5 0,000 0,02156156 0,12746217 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02156156 0,12714976 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02156156 0,12683888 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02156156 0,12652952 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02156156 0,12622166 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02156156 0,1259153 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02156156 0,12561042 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02156156 0,12530701 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02156156 0,12500507 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02156156 0,12470457 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02156156 0,12440552 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02156156 0,1241079 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02156156 0,1238117 ! negative chemotaxis GO:0050919 14 5 0,000 0,02156156 0,12351691 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02156156 0,12322352 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02156156 0,12293152 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02156156 0,1226409 ! behavioral response to pain GO:0048266 9 5 0,000 0,02156156 0,12235166 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02156156 0,12206377 ! Notch receptor processing GO:0007220 8 5 0,000 0,02156156 0,12177724 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02156156 0,12149204 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02156156 0,12120818 ! micturition GO:0060073 9 5 0,000 0,02156156 0,12092565 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02156156 0,12064443 ! copulation GO:0007620 9 5 0,000 0,02156156 0,12036451 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02156156 0,12008589 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02156156 0,11980855 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02156156 0,11953249 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02156156 0,11925771 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02156156 0,11898418 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02156156 0,11871191 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02156156 0,11844087 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02156156 0,11817108 ! grooming behavior GO:0007625 6 5 0,000 0,02156156 0,11790251 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02156156 0,11763515 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02156156 0,11736901 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02156156 0,11710407 ! response to protozoan GO:0001562 10 5 0,000 0,02156156 0,11684032 ! lymph vessel development GO:0001945 10 5 0,000 0,02156156 0,11657776 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02156156 0,11631637 ! endochondral ossification GO:0001958 16 5 0,000 0,02156156 0,11605616 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02156156 0,1157971 ! parathyroid gland development GO:0060017 13 5 0,000 0,02156156 0,1155392 ! anagen GO:0042640 6 5 0,000 0,02156156 0,11528245 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02156156 0,11502684 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02156156 0,11477235 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02156156 0,11451899 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02156156 0,11426675 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02156156 0,11401561 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02156156 0,11376558 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02156156 0,11351664 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02156156 0,11326878 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02156156 0,11302201 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02156156 0,11277631 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02156156 0,11253168 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02156156 0,1122881 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02156156 0,11204558 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02156156 0,1118041 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02156156 0,11156366 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02156156 0,11132425 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02156156 0,11108587 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02156156 0,11084851 ! histidine catabolic process GO:0006548 6 5 0,000 0,02156156 0,11061216 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02156156 0,11037681 ! microvillus organization GO:0032528 7 5 0,000 0,02156156 0,11014247 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02156156 0,10990912 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02156156 0,10967675 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02156156 0,10944536 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02156156 0,10921495 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02156156 0,10898551 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02156156 0,10875703 ! polyol catabolic process GO:0046174 7 5 0,000 0,02156156 0,1085295 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02156156 0,10830293 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02156156 0,1080773 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02156156 0,1078526 ! muscle cell migration GO:0014812 8 5 0,000 0,02156156 0,10762884 ! mitochondrial fission GO:0000266 8 5 0,000 0,02156156 0,10740601 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02156156 0,1071841 ! mRNA transcription GO:0009299 9 5 0,000 0,02156156 0,1069631 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02156156 0,10674301 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02156156 0,10652382 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02156156 0,10630554 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02156156 0,10608814 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02156156 0,10587164 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02156156 0,10565601 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02156156 0,10544127 ! response to food GO:0032094 6 5 0,000 0,02156156 0,10522739 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02156156 0,10501438 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02156156 0,10480223 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02156156 0,10459093 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02156156 0,10438049 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02156156 0,10417089 ! forebrain neuron development GO:0021884 13 5 0,000 0,02156156 0,10396213 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02156156 0,10375421 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02156156 0,10354711 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02156156 0,10334084 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02156156 0,10313539 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02156156 0,10293076 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02156156 0,10272694 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02156156 0,10252392 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02156156 0,1023217 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02156156 0,10212028 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02156156 0,10191965 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02156156 0,10171981 ! basic amino acid transport GO:0015802 11 5 0,000 0,02156156 0,10152075 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02156156 0,10132247 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02156156 0,10112496 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02156156 0,10092822 ! depyrimidination GO:0045008 10 5 0,000 0,02156156 0,10073224 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02156156 0,10053702 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02156156 0,10034256 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02156156 0,10014885 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02156156 0,09995588 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02156156 0,09976366 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02156156 0,09957217 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02156156 0,09938142 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02156156 0,0991914 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02156156 0,0990021 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02156156 0,09881353 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02156156 0,09862567 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02156156 0,09843853 ! response to arsenic GO:0046685 10 5 0,000 0,02156156 0,09825209 ! mast cell degranulation GO:0043303 7 5 0,000 0,02156156 0,09806636 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02156156 0,09788133 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02156156 0,09769699 ! response to cadmium ion GO:0046686 7 5 0,000 0,02156156 0,09751335 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02156156 0,0973304 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02156156 0,09714813 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02156156 0,09696655 ! decidualization GO:0046697 11 5 0,000 0,02156156 0,09678564 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02156156 0,09660541 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02156156 0,09642584 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02156156 0,09624694 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02156156 0,09606871 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02156156 0,09589113 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02156156 0,09571421 ! neural tube patterning GO:0021532 7 5 0,000 0,02156156 0,09553794 ! embryonic cleavage GO:0040016 6 5 0,000 0,02156156 0,09536232 ! peroxisome fission GO:0016559 5 5 0,000 0,02156156 0,09518734 ! histone demethylation GO:0016577 10 5 0,000 0,02156156 0,09501301 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02156156 0,09483931 ! mitotic recombination GO:0006312 9 5 0,000 0,02156156 0,09466625 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02156156 0,09449381 ! metaphase plate congression GO:0051310 7 5 0,000 0,02156156 0,09432201 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02156156 0,09415082 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02156156 0,09398026 ! enteric nervous system development GO:0048484 8 5 0,000 0,02156156 0,09381031 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02156156 0,09364098 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02156156 0,09347226 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02156156 0,09330414 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02156156 0,09313663 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02156156 0,09296972 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02156156 0,0928034 ! plasminogen activation GO:0031639 5 5 0,000 0,02156156 0,09263768 ! B cell homeostasis GO:0001782 13 5 0,000 0,02156156 0,09247255 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02156156 0,09230801 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02156156 0,09214405 ! metaphase GO:0051323 8 5 0,000 0,02156156 0,09198068 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02156156 0,09181788 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02156156 0,09165566 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02156156 0,09149401 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02156156 0,09133293 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02156156 0,09117241 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02156156 0,09101246 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02156156 0,09085307 ! response to redox state GO:0051775 5 5 0,000 0,02156156 0,09069424 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02156156 0,09053596 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02156156 0,09037823 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02156156 0,09022105 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02156156 0,09006441 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02156156 0,08990832 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02156156 0,08975277 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02156156 0,08959776 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02156156 0,08944328 ! striatum development GO:0021756 9 5 0,000 0,02156156 0,08928933 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02156156 0,08913592 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02156156 0,08898302 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02156156 0,08883066 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02156156 0,08867881 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02156156 0,08852748 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02156156 0,08837667 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02156156 0,08822637 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02156156 0,08807658 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02156156 0,08792729 ! neuroprotection GO:0043526 6 5 0,000 0,02156156 0,08777852 ! neural plate development GO:0001840 8 5 0,000 0,02156156 0,08763024 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02156156 0,08748247 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02156156 0,08733519 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02156156 0,08718841 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02156156 0,08704212 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02156156 0,08689632 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02156156 0,08675101 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02156156 0,08660618 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02156156 0,08646184 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02156156 0,08631797 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02156156 0,08617459 ! spindle assembly GO:0051225 6 5 0,000 0,02156156 0,08603168 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02156156 0,08588924 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02156156 0,08574728 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02156156 0,08560578 ! drug metabolic process GO:0017144 6 5 0,000 0,02156156 0,08546475 ! stem cell division GO:0017145 11 5 0,000 0,02156156 0,08532418 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02156156 0,08518408 ! organ regeneration GO:0031100 7 5 0,000 0,02156156 0,08504443 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02156156 0,08490524 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02156156 0,08476651 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02156156 0,08462823 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,02160542 0,08466229 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02160542 0,08452463 ! RNA catabolic process GO:0006401 93 53 1,000 0,02238966 0,08745053 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,02238966 0,0873088 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,02238966 0,08716752 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,02238966 0,0870267 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,02318555 0,08997491 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 1,000 0,02318555 0,08983002 ! heterocycle catabolic process GO:0046700 85 54 1,000 0,02318555 0,0896856 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,02399298 0,0926599 ! aging GO:0007568 103 55 1,000 0,02399298 0,09251141 ! heart morphogenesis GO:0003007 97 55 1,000 0,02399298 0,09236339 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,02399298 0,09221584 ! regulation of actin filament length GO:0030832 105 56 1,000 0,02481184 0,09521097 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,02481184 0,09505936 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,02481184 0,09490823 ! lipid modification GO:0030258 97 57 1,000 0,025642 0,09792801 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,025642 0,09777282 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,025642 0,09761811 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02581818 0,09813355 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02581818 0,09797877 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02581818 0,09782447 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02581818 0,09767066 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02581818 0,09751733 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02581818 0,09736448 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02581818 0,09721211 ! sleep GO:0030431 13 6 0,000 0,02581818 0,09706022 ! response to oxygen radical GO:0000305 11 6 0,000 0,02581818 0,0969088 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02581818 0,09675785 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02581818 0,09660737 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02581818 0,09645736 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02581818 0,09630781 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02581818 0,09615873 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02581818 0,09601011 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02581818 0,09586194 ! forebrain regionalization GO:0021871 8 6 0,000 0,02581818 0,09571423 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02581818 0,09556698 ! male meiosis GO:0007140 7 6 0,000 0,02581818 0,09542018 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02581818 0,09527383 ! response to zinc ion GO:0010043 9 6 0,000 0,02581818 0,09512793 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02581818 0,09498247 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02581818 0,09483746 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02581818 0,09469289 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02581818 0,09454876 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02581818 0,09440507 ! malate metabolic process GO:0006108 11 6 0,000 0,02581818 0,09426182 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02581818 0,094119 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02581818 0,09397661 ! protein refolding GO:0042026 15 6 0,000 0,02581818 0,09383465 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02581818 0,09369312 ! opsonization GO:0008228 8 6 0,000 0,02581818 0,09355202 ! mating behavior GO:0007617 7 6 0,000 0,02581818 0,09341134 ! neuron remodeling GO:0016322 15 6 0,000 0,02581818 0,09327108 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02581818 0,09313124 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02581818 0,09299182 ! equilibrioception GO:0050957 14 6 0,000 0,02581818 0,09285282 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02581818 0,09271424 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02581818 0,09257606 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02581818 0,0924383 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02581818 0,09230095 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02581818 0,092164 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02581818 0,09202746 ! toxin metabolic process GO:0009404 11 6 0,000 0,02581818 0,09189133 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02581818 0,0917556 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02581818 0,09162026 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02581818 0,09148533 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02581818 0,09135079 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02581818 0,09121665 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02581818 0,0910829 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02581818 0,09094954 ! thymic T cell selection GO:0045061 12 6 0,000 0,02581818 0,09081658 ! protein lipoylation GO:0009249 10 6 0,000 0,02581818 0,090684 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02581818 0,0905518 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02581818 0,09042 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02581818 0,09028857 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02581818 0,09015753 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02581818 0,09002687 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02581818 0,08989658 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02581818 0,08976667 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02581818 0,08963714 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02581818 0,08950798 ! hyperosmotic response GO:0006972 9 6 0,000 0,02581818 0,08937919 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02581818 0,08925077 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02581818 0,08912272 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02581818 0,08899504 ! urea metabolic process GO:0019627 7 6 0,000 0,02581818 0,08886772 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02581818 0,08874077 ! neutrophil activation GO:0042119 8 6 0,000 0,02581818 0,08861418 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02581818 0,08848795 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02581818 0,08836207 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02581818 0,08823656 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02581818 0,0881114 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02581818 0,0879866 ! neuron apoptosis GO:0051402 9 6 0,000 0,02581818 0,08786215 ! nucleoside salvage GO:0043174 9 6 0,000 0,02581818 0,08773805 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02581818 0,0876143 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02581818 0,0874909 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02581818 0,08736785 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02581818 0,08724514 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02581818 0,08712277 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02581818 0,08700075 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02581818 0,08687907 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02581818 0,08675773 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02581818 0,08663673 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02581818 0,08651607 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02581818 0,08639574 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02581818 0,08627575 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02581818 0,08615609 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02581818 0,08603676 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02581818 0,08591776 ! monocyte differentiation GO:0030224 12 6 0,000 0,02581818 0,08579909 ! neural nucleus development GO:0048857 14 6 0,000 0,02581818 0,08568074 ! response to UV-C GO:0010225 11 6 0,000 0,02581818 0,08556272 ! astrocyte development GO:0014002 15 6 0,000 0,02581818 0,08544503 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02581818 0,08532766 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02581818 0,08521061 ! interaction with symbiont GO:0051702 13 6 0,000 0,02581818 0,08509389 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02581818 0,08497748 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02581818 0,08486139 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02581818 0,08474562 ! response to copper ion GO:0046688 10 6 0,000 0,02581818 0,08463016 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02581818 0,08451502 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02581818 0,08440019 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02581818 0,08428567 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02581818 0,08417146 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02581818 0,08405756 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02581818 0,08394397 ! hair follicle maturation GO:0048820 7 6 0,000 0,02581818 0,08383069 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02581818 0,08371771 ! Schwann cell development GO:0014044 15 6 0,000 0,02581818 0,08360503 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02581818 0,08349266 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02581818 0,08338059 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02581818 0,08326882 ! subpallium development GO:0021544 10 6 0,000 0,02581818 0,08315735 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02581818 0,08304617 ! histone ubiquitination GO:0016574 8 6 0,000 0,02581818 0,0829353 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02581818 0,08282472 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02581818 0,08271443 ! G2 phase GO:0051319 16 6 0,000 0,02581818 0,08260444 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02581818 0,08249474 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02581818 0,08238533 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02581818 0,08227621 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02581818 0,08216738 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02581818 0,08205883 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02581818 0,08195058 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02581818 0,08184261 ! receptor internalization GO:0031623 10 6 0,000 0,02581818 0,08173492 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02581818 0,08162751 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02581818 0,08152039 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02581818 0,08141355 ! protein deubiquitination GO:0016579 14 6 0,000 0,02581818 0,08130699 ! protein destabilization GO:0031648 9 6 0,000 0,02581818 0,0812007 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02581818 0,0810947 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02581818 0,08098897 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02581818 0,08088351 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02581818 0,08077833 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02581818 0,08067343 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02581818 0,08056879 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02581818 0,08046443 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02581818 0,08036033 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02581818 0,08025651 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02581818 0,08015295 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02581818 0,08004966 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02581818 0,07994664 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02581818 0,07984388 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02581818 0,07974138 ! catecholamine transport GO:0051937 9 6 0,000 0,02581818 0,07963915 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02581818 0,07953718 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02581818 0,07943547 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02581818 0,07933402 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02581818 0,07923283 ! maternal placenta development GO:0001893 12 6 0,000 0,02581818 0,0791319 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02581818 0,07903122 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02581818 0,0789308 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02581818 0,07883063 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02581818 0,07873072 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02581818 0,07863106 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02581818 0,07853165 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02581818 0,0784325 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,02648336 0,08035178 ! regulation of cellular component size GO:0032535 109 59 1,000 0,02733581 0,08283369 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,02819923 0,08534258 ! tRNA transcription GO:0009304 14 7 0,000 0,03005642 0,09084894 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03005642 0,09073495 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03005642 0,09062125 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03005642 0,09050783 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03005642 0,0903947 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03005642 0,09028184 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03005642 0,09016927 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03005642 0,09005698 ! prostate gland development GO:0030850 13 7 0,000 0,03005642 0,08994497 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03005642 0,08983324 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03005642 0,08972178 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03005642 0,0896106 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03005642 0,0894997 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03005642 0,08938907 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03005642 0,08927871 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03005642 0,08916863 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03005642 0,08905881 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03005642 0,08894927 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03005642 0,08884 ! glycolipid transport GO:0046836 10 7 0,000 0,03005642 0,08873099 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03005642 0,08862225 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03005642 0,08851378 ! neuron adhesion GO:0007158 12 7 0,000 0,03005642 0,08840557 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03005642 0,08829763 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03005642 0,08818995 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03005642 0,08808253 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03005642 0,08797537 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03005642 0,08786848 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03005642 0,08776184 ! mRNA stabilization GO:0048255 18 7 0,000 0,03005642 0,08765546 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03005642 0,08754934 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03005642 0,08744348 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03005642 0,08733787 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03005642 0,08723252 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03005642 0,08712742 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03005642 0,08702257 ! lipoprotein transport GO:0042953 14 7 0,000 0,03005642 0,08691798 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03005642 0,08681363 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03005642 0,08670954 ! rhythmic behavior GO:0007622 15 7 0,000 0,03005642 0,0866057 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03005642 0,0865021 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03005642 0,08639875 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03005642 0,08629565 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03005642 0,0861928 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03005642 0,08609019 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03005642 0,08598782 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03005642 0,0858857 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03005642 0,08578382 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03005642 0,08568218 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03005642 0,08558078 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03005642 0,08547962 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03005642 0,0853787 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03005642 0,08527802 ! spinal cord patterning GO:0021511 13 7 0,000 0,03005642 0,08517757 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03005642 0,08507736 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03005642 0,08497739 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03005642 0,08487765 ! adrenal gland development GO:0030325 17 7 0,000 0,03005642 0,08477814 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03005642 0,08467887 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03005642 0,08457983 ! ovulation GO:0030728 9 7 0,000 0,03005642 0,08448102 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03005642 0,08438245 ! microtubule nucleation GO:0007020 20 7 0,000 0,03005642 0,0842841 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03005642 0,08418598 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03005642 0,08408809 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03005642 0,08399043 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03005642 0,08389299 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03005642 0,08379578 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03005642 0,08369879 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03005642 0,08360203 ! galactose metabolic process GO:0006012 13 7 0,000 0,03005642 0,08350549 ! vesicle fusion GO:0006906 17 7 0,000 0,03005642 0,08340918 ! response to dietary excess GO:0002021 8 7 0,000 0,03005642 0,08331308 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03005642 0,08321721 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03005642 0,08312156 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03005642 0,08302613 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03005642 0,08293091 ! organ growth GO:0035265 15 7 0,000 0,03005642 0,08283592 ! purine salvage GO:0043101 10 7 0,000 0,03005642 0,08274114 ! nucleoside transport GO:0015858 8 7 0,000 0,03005642 0,08264658 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03005642 0,08255223 ! parturition GO:0007567 14 7 0,000 0,03005642 0,0824581 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03005642 0,08236419 ! rRNA modification GO:0000154 14 7 0,000 0,03005642 0,08227049 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03005642 0,082177 ! spindle checkpoint GO:0031577 15 7 0,000 0,03005642 0,08208372 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03005642 0,08199065 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03005642 0,0818978 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03005642 0,08180516 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03005642 0,08171272 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03005642 0,08162049 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03005642 0,08152848 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03005642 0,08143666 ! fibrinolysis GO:0042730 10 7 0,000 0,03005642 0,08134506 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03005642 0,08125366 ! eating behavior GO:0042755 7 7 0,000 0,03005642 0,08116247 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03005642 0,08107148 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03005642 0,08098069 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03005642 0,08089011 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03005642 0,08079973 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03005642 0,08070955 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03005642 0,08061957 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03005642 0,0805298 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03005642 0,08044022 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03005642 0,08035084 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03005642 0,08026166 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03005642 0,08017268 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03005642 0,0800839 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03005642 0,07999531 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03005642 0,07990691 ! regulation of meiosis GO:0040020 12 7 0,000 0,03005642 0,07981872 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03005642 0,07973071 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03005642 0,0796429 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03005642 0,07955529 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03005642 0,07946787 ! transcription termination GO:0006353 13 7 0,000 0,03005642 0,07938063 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03005642 0,07929359 ! anaphase GO:0051322 17 7 0,000 0,03005642 0,07920674 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03005642 0,07912008 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03005642 0,07903361 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03005642 0,07894733 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03005642 0,07886124 ! diuresis GO:0030146 12 7 0,000 0,03005642 0,07877533 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03005642 0,07868962 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03005642 0,07860408 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03005642 0,07851874 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03005642 0,07843358 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03005642 0,0783486 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03005642 0,07826381 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03005642 0,0781792 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03005642 0,07809477 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03005642 0,07801053 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03005642 0,07792646 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03005642 0,07784258 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03005642 0,07775888 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03005642 0,07767536 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03005642 0,07759201 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03005642 0,07750885 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03005642 0,07742586 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03005642 0,07734306 ! adult feeding behavior GO:0008343 9 7 0,000 0,03005642 0,07726042 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03005642 0,07717797 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03005642 0,07709569 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03005642 0,07701359 ! muscle adaptation GO:0043500 14 7 0,000 0,03005642 0,07693166 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03005642 0,0768499 ! retina homeostasis GO:0001895 12 7 0,000 0,03005642 0,07676832 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03005642 0,07668691 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03005642 0,07660568 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03005642 0,07652461 ! protein prenylation GO:0018342 18 7 0,000 0,03005642 0,07644372 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03005642 0,076363 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03005642 0,07628244 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03005642 0,07620206 ! regulation of mitosis GO:0007088 105 63 1,000 0,03085426 0,07814247 GO:0051783|regulation of nuclear division, ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,03085426 0,0780603 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03427637 0,08662705 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03427637 0,08653615 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03427637 0,08644544 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03427637 0,08635492 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03427637 0,08626459 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03427637 0,08617445 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03427637 0,0860845 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03427637 0,08599473 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03427637 0,08590516 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03427637 0,08581577 ! meiotic prophase I GO:0007128 13 8 0,000 0,03427637 0,08572656 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03427637 0,08563754 ! oligopeptide transport GO:0006857 15 8 0,000 0,03427637 0,0855487 ! UTP metabolic process GO:0046051 8 8 0,000 0,03427637 0,08546005 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03427637 0,08537158 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03427637 0,0852833 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03427637 0,0851952 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03427637 0,08510728 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03427637 0,08501954 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03427637 0,08493198 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03427637 0,0848446 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03427637 0,0847574 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03427637 0,08467038 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03427637 0,08458354 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03427637 0,08449688 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03427637 0,08441039 ! reflex GO:0060004 16 8 0,000 0,03427637 0,08432408 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03427637 0,08423795 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03427637 0,08415199 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03427637 0,08406621 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03427637 0,0839806 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03427637 0,08389517 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03427637 0,08380991 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03427637 0,08372482 ! pigment granule organization GO:0048753 16 8 0,000 0,03427637 0,08363991 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03427637 0,08355517 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03427637 0,0834706 ! histidine metabolic process GO:0006547 16 8 0,000 0,03427637 0,0833862 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03427637 0,08330197 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03427637 0,08321791 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03427637 0,08313402 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03427637 0,0830503 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03427637 0,08296675 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03427637 0,08288337 ! melanin metabolic process GO:0006582 15 8 0,000 0,03427637 0,08280015 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03427637 0,0827171 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03427637 0,08263422 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03427637 0,0825515 ! macrophage activation GO:0042116 12 8 0,000 0,03427637 0,08246895 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03427637 0,08238656 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03427637 0,08230434 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03427637 0,08222228 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03427637 0,08214039 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03427637 0,08205866 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03427637 0,08197709 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03427637 0,08189568 ! osteoblast development GO:0002076 16 8 0,000 0,03427637 0,08181443 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03427637 0,08173335 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03427637 0,08165243 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03427637 0,08157166 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03427637 0,08149106 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03427637 0,08141061 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03427637 0,08133033 ! response to UV-B GO:0010224 16 8 0,000 0,03427637 0,0812502 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03427637 0,08117023 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03427637 0,08109041 ! intermediate filament organization GO:0045109 12 8 0,000 0,03427637 0,08101076 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03427637 0,08093126 ! cellular extravasation GO:0045123 12 8 0,000 0,03427637 0,08085191 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03427637 0,08077272 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03427637 0,08069369 ! response to antibiotic GO:0046677 11 8 0,000 0,03427637 0,08061481 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03427637 0,08053608 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03427637 0,08045751 ! DNA topological change GO:0006265 12 8 0,000 0,03427637 0,08037909 ! response to tropane GO:0014073 15 8 0,000 0,03427637 0,08030083 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03427637 0,08022271 ! melanosome transport GO:0032402 13 8 0,000 0,03427637 0,08014475 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03427637 0,08006694 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03427637 0,07998928 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03427637 0,07991177 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03427637 0,07983441 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03427637 0,07975721 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03427637 0,07968015 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03427637 0,07960323 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03427637 0,07952647 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03427637 0,07944986 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03427637 0,07937339 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03427637 0,07929707 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03427637 0,07922089 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03427637 0,07914487 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03427637 0,07906898 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03427637 0,07899325 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03427637 0,07891766 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03427637 0,07884221 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03427637 0,07876691 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03427637 0,07869175 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03427637 0,07861673 ! hormone catabolic process GO:0042447 17 8 0,000 0,03427637 0,07854186 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03427637 0,07846713 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03427637 0,07839254 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03427637 0,07831809 ! ATP catabolic process GO:0006200 11 8 0,000 0,03427637 0,07824379 ! blastocyst growth GO:0001832 19 8 0,000 0,03427637 0,07816962 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03427637 0,0780956 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03427637 0,07802171 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03427637 0,07794797 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03427637 0,07787436 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03427637 0,0778009 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03427637 0,07772757 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03427637 0,07765438 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03427637 0,07758133 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03427637 0,07750841 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03427637 0,07743563 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03427637 0,07736299 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03427637 0,07729049 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03427637 0,07721812 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03427637 0,07714588 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03427637 0,07707379 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03427637 0,07700182 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03427637 0,07692999 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,03454137 0,0774525 ! chromosome segregation GO:0007059 113 67 1,000 0,03454137 0,07738038 ! regulation of lipase activity GO:0060191 130 68 1,000 0,0354887 0,07942865 ! antigen processing and presentation GO:0019882 104 69 1,000 0,03644604 0,08149551 ! amine catabolic process GO:0009310 117 71 1,000 0,03839034 0,08576339 ! regulation of immune effector process GO:0002697 137 71 1,000 0,03839034 0,08568383 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0384781 0,0858001 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,0384781 0,08572065 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0384781 0,08564136 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0384781 0,0855622 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,0384781 0,0854832 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,0384781 0,08540434 ! phosphate transport GO:0006817 19 9 0,000 0,0384781 0,08532563 ! reproductive behavior GO:0019098 19 9 0,000 0,0384781 0,08524706 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0384781 0,08516863 ! CTP metabolic process GO:0046036 9 9 0,000 0,0384781 0,08509035 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0384781 0,08501222 ! GTP metabolic process GO:0046039 9 9 0,000 0,0384781 0,08493422 ! RNA methylation GO:0001510 15 9 0,000 0,0384781 0,08485638 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0384781 0,08477867 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,0384781 0,0847011 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,0384781 0,08462368 ! artery development GO:0060840 24 9 0,000 0,0384781 0,0845464 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0384781 0,08446926 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0384781 0,08439226 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,0384781 0,0843154 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,0384781 0,08423868 ! chemosensory behavior GO:0007635 20 9 0,000 0,0384781 0,0841621 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0384781 0,08408565 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0384781 0,08400935 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,0384781 0,08393319 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0384781 0,08385716 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0384781 0,08378127 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,0384781 0,08370552 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0384781 0,08362991 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0384781 0,08355443 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0384781 0,08347908 ! protein targeting to ER GO:0045047 22 9 0,000 0,0384781 0,08340388 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0384781 0,08332881 ! T cell selection GO:0045058 23 9 0,000 0,0384781 0,08325387 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0384781 0,08317907 ! endosome organization GO:0007032 17 9 0,000 0,0384781 0,0831044 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0384781 0,08302987 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0384781 0,08295547 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0384781 0,0828812 ! mannose metabolic process GO:0006013 13 9 0,000 0,0384781 0,08280707 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0384781 0,08273307 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0384781 0,0826592 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0384781 0,08258546 ! receptor clustering GO:0043113 18 9 0,000 0,0384781 0,08251186 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0384781 0,08243838 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0384781 0,08236504 ! ruffle organization GO:0031529 15 9 0,000 0,0384781 0,08229183 ! retinol metabolic process GO:0042572 18 9 0,000 0,0384781 0,08221874 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0384781 0,08214579 ! behavioral fear response GO:0001662 22 9 0,000 0,0384781 0,08207297 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0384781 0,08200027 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0384781 0,0819277 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0384781 0,08185527 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,0384781 0,08178296 ! oligodendrocyte development GO:0014003 10 9 0,000 0,0384781 0,08171077 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,0384781 0,08163872 ! segment specification GO:0007379 13 9 0,000 0,0384781 0,08156679 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0384781 0,08149499 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0384781 0,08142331 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0384781 0,08135176 ! response to amine stimulus GO:0014075 13 9 0,000 0,0384781 0,08128034 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0384781 0,08120904 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0384781 0,08113787 ! erythrocyte development GO:0048821 15 9 0,000 0,0384781 0,08106682 ! gas homeostasis GO:0033483 16 9 0,000 0,0384781 0,08099589 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0384781 0,08092509 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,0384781 0,08085441 ! renal water homeostasis GO:0003091 14 9 0,000 0,0384781 0,08078386 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0384781 0,08071343 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0384781 0,08064312 ! icosanoid secretion GO:0032309 15 9 0,000 0,0384781 0,08057294 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,0384781 0,08050287 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0384781 0,08043293 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0384781 0,08036311 ! regulation of cell division GO:0051302 15 9 0,000 0,0384781 0,08029341 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0384781 0,08022383 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0384781 0,08015438 ! sterol catabolic process GO:0016127 11 9 0,000 0,0384781 0,08008504 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0384781 0,08001582 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0384781 0,07994672 ! S phase GO:0051320 9 9 0,000 0,0384781 0,07987774 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,0384781 0,07980888 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0384781 0,07974014 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0384781 0,07967152 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0384781 0,07960301 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0384781 0,07953463 ! purine base metabolic process GO:0006144 21 9 0,000 0,0384781 0,07946636 ! pigment granule transport GO:0051904 17 9 0,000 0,0384781 0,0793982 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0384781 0,07933017 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,0384781 0,07926225 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0384781 0,07919444 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0384781 0,07912676 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0384781 0,07905918 ! mitochondrion localization GO:0051646 15 9 0,000 0,0384781 0,07899173 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0393771 0,08076838 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,0393771 0,08069958 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,04137932 0,08473077 GO:0090046|regulation of transcription regulator activity, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,04137932 0,08465872 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04266168 0,08720816 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04266168 0,08713413 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04266168 0,08706023 ! synapsis GO:0007129 13 10 0,000 0,04266168 0,08698645 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04266168 0,08691279 ! N-glycan processing GO:0006491 20 10 0,000 0,04266168 0,08683926 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04266168 0,08676586 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04266168 0,08669258 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04266168 0,08661942 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04266168 0,08654638 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,04266168 0,08647347 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04266168 0,08640068 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04266168 0,08632802 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04266168 0,08625547 ! androgen metabolic process GO:0008209 17 10 0,000 0,04266168 0,08618305 ! phospholipid efflux GO:0033700 16 10 0,000 0,04266168 0,08611075 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04266168 0,08603857 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04266168 0,08596651 ! lung alveolus development GO:0048286 26 10 0,000 0,04266168 0,08589457 ! pathogenesis GO:0009405 13 10 0,000 0,04266168 0,08582275 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04266168 0,08575105 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04266168 0,08567947 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04266168 0,08560802 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04266168 0,08553668 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04266168 0,08546545 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04266168 0,08539435 ! arginine catabolic process GO:0006527 13 10 0,000 0,04266168 0,08532337 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04266168 0,0852525 ! proline metabolic process GO:0006560 13 10 0,000 0,04266168 0,08518175 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04266168 0,08511112 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04266168 0,0850406 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04266168 0,08497021 ! V(D)J recombination GO:0033151 28 10 0,000 0,04266168 0,08489993 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04266168 0,08482976 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04266168 0,08475971 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04266168 0,08468978 ! B cell proliferation GO:0042100 18 10 0,000 0,04266168 0,08461996 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04266168 0,08455026 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04266168 0,08448067 ! multicellular organism growth GO:0035264 18 10 0,000 0,04266168 0,08441119 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04266168 0,08434183 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04266168 0,08427259 ! epithelial cell development GO:0002064 20 10 0,000 0,04266168 0,08420345 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04266168 0,08413443 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04266168 0,08406553 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04266168 0,08399673 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04266168 0,08392805 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04266168 0,08385949 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04266168 0,08379103 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04266168 0,08372268 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04266168 0,08365445 ! brain morphogenesis GO:0048854 23 10 0,000 0,04266168 0,08358633 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04266168 0,08351832 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04266168 0,08345041 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04266168 0,08338262 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04266168 0,08331494 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04266168 0,08324737 ! response to dsRNA GO:0043331 20 10 0,000 0,04266168 0,08317991 ! DNA ligation GO:0006266 19 10 0,000 0,04266168 0,08311256 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04266168 0,08304532 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04266168 0,08297818 ! melanosome localization GO:0032400 16 10 0,000 0,04266168 0,08291116 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04266168 0,08284424 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04266168 0,08277743 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04266168 0,08271073 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04266168 0,08264413 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04266168 0,08257764 ! mRNA cleavage GO:0006379 17 10 0,000 0,04266168 0,08251126 ! protein sumoylation GO:0016925 15 10 0,000 0,04266168 0,08244499 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04266168 0,08237882 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04266168 0,08231276 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04266168 0,0822468 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04266168 0,08218095 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04266168 0,08211521 ! salivary gland development GO:0007431 27 10 0,000 0,04266168 0,08204957 ! prophase GO:0051324 15 10 0,000 0,04266168 0,08198403 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04266168 0,0819186 ! apical protein localization GO:0045176 15 10 0,000 0,04266168 0,08185328 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04266168 0,08178806 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04266168 0,08172294 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04266168 0,08165792 ! midbrain development GO:0030901 13 10 0,000 0,04266168 0,08159301 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04266168 0,0815282 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04266168 0,0814635 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04266168 0,0813989 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04266168 0,0813344 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04266168 0,08127 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04266168 0,0812057 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04266168 0,08114151 ! detection of calcium ion GO:0005513 23 10 0,000 0,04266168 0,08107742 ! oocyte development GO:0048599 17 10 0,000 0,04266168 0,08101343 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04266168 0,08094953 ! blastocyst formation GO:0001825 17 10 0,000 0,04266168 0,08088574 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04266168 0,08082206 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04266168 0,08075847 ! activation of innate immune response GO:0002218 12 10 0,000 0,04266168 0,08069498 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04266168 0,08063159 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04266168 0,0805683 ! response to nicotine GO:0035094 20 10 0,000 0,04266168 0,08050511 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04266168 0,08044201 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04266168 0,08037902 ! regulation of catabolic process GO:0009894 161 76 1,000 0,04341915 0,08174215 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,04445291 0,08362291 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,04549578 0,08551785 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,04654766 0,08742675 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,0468272 0,08788319 ! respiratory burst GO:0045730 17 11 0,000 0,0468272 0,08781469 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0468272 0,0877463 ! neuron fate specification GO:0048665 17 11 0,000 0,0468272 0,08767802 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0468272 0,08760984 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0468272 0,08754177 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0468272 0,0874738 ! thyroid gland development GO:0030878 26 11 0,000 0,0468272 0,08740594 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0468272 0,08733818 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0468272 0,08727053 ! response to pain GO:0048265 24 11 0,000 0,0468272 0,08720298 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0468272 0,08713554 ! T cell proliferation GO:0042098 26 11 0,000 0,0468272 0,0870682 ! blood vessel remodeling GO:0001974 29 11 0,000 0,0468272 0,08700097 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,0468272 0,08693384 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,0468272 0,08686681 ! bone resorption GO:0045453 16 11 0,000 0,0468272 0,08679989 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0468272 0,08673307 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0468272 0,08666635 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0468272 0,08659973 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0468272 0,08653322 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0468272 0,08646681 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0468272 0,0864005 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0468272 0,08633429 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0468272 0,08626819 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0468272 0,08620218 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,0468272 0,08613628 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0468272 0,08607048 ! UV protection GO:0009650 19 11 0,000 0,0468272 0,08600477 ! adult heart development GO:0007512 14 11 0,000 0,0468272 0,08593917 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0468272 0,08587367 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0468272 0,08580826 ! temperature homeostasis GO:0001659 17 11 0,000 0,0468272 0,08574296 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0468272 0,08567776 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0468272 0,08561265 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,0468272 0,08554765 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0468272 0,08548274 ! regulation of organ growth GO:0046620 13 11 0,000 0,0468272 0,08541793 ! pigment granule localization GO:0051875 20 11 0,000 0,0468272 0,08535322 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0468272 0,08528861 ! vasoconstriction GO:0042310 18 11 0,000 0,0468272 0,08522409 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0468272 0,08515968 ! embryonic axis specification GO:0000578 18 11 0,000 0,0468272 0,08509536 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0468272 0,08503113 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0468272 0,08496701 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0468272 0,08490298 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0468272 0,08483905 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0468272 0,08477521 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0468272 0,08471147 ! zymogen activation GO:0031638 15 11 0,000 0,0468272 0,08464782 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0468272 0,08458427 ! nucleosome positioning GO:0016584 15 11 0,000 0,0468272 0,08452082 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0468272 0,08445746 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0468272 0,0843942 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0468272 0,08433103 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,0468272 0,08426795 ! acid secretion GO:0046717 18 11 0,000 0,0468272 0,08420497 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0468272 0,08414209 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0468272 0,08407929 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0468272 0,08401659 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0468272 0,08395399 ! oocyte differentiation GO:0009994 18 11 0,000 0,0468272 0,08389148 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0468272 0,08382906 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,0468272 0,08376673 ! cholesterol efflux GO:0033344 19 11 0,000 0,0468272 0,0837045 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0468272 0,08364235 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0468272 0,08358031 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0468272 0,08351835 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,0468272 0,08345648 ! embryonic gut development GO:0048566 15 11 0,000 0,0468272 0,08339471 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0468272 0,08333303 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0468272 0,08327144 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0468272 0,08320993 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0468272 0,08314853 ! defense response to fungus GO:0050832 13 11 0,000 0,0468272 0,08308721 ! developmental induction GO:0031128 19 11 0,000 0,0468272 0,08302598 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,0468272 0,08296484 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0468272 0,08290379 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0468272 0,08284283 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0468272 0,08278196 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0468272 0,08272118 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0468272 0,08266049 ! response to metal ion GO:0010038 140 80 1,000 0,04760845 0,08397795 ! muscle cell differentiation GO:0042692 159 80 1,000 0,04760845 0,08391643 ! response to hypoxia GO:0001666 171 81 1,000 0,04867805 0,08573893 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,04867805 0,08567621 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,04867805 0,08561358 ! response to drug GO:0042493 143 82 1,000 0,04975637 0,08744618 ! response to oxygen levels GO:0070482 176 83 1,000 0,05084331 0,08929125 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05097474 0,08945676 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05097474 0,08939156 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05097474 0,08932645 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05097474 0,08926144 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05097474 0,08919652 ! cartilage condensation GO:0001502 20 12 0,000 0,05097474 0,0891317 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05097474 0,08906697 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05097474 0,08900233 ! protein complex disassembly GO:0043241 27 12 0,000 0,05097474 0,08893779 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05097474 0,08887335 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05097474 0,08880899 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05097474 0,08874473 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05097474 0,08868056 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05097474 0,08861649 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05097474 0,0885525 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05097474 0,08848861 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05097474 0,08842481 ! drug transport GO:0015893 16 12 0,000 0,05097474 0,08836111 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05097474 0,08829749 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05097474 0,08823397 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05097474 0,08817054 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05097474 0,0881072 ! focal adhesion formation GO:0048041 35 12 0,000 0,05097474 0,08804395 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05097474 0,08798079 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05097474 0,08791772 ! forebrain cell migration GO:0021885 21 12 0,000 0,05097474 0,08785474 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05097474 0,08779185 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05097474 0,08772905 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05097474 0,08766635 ! fear response GO:0042596 26 12 0,000 0,05097474 0,08760373 ! monoamine transport GO:0015844 18 12 0,000 0,05097474 0,0875412 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05097474 0,08747876 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05097474 0,08741641 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05097474 0,08735414 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05097474 0,08729197 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05097474 0,08722988 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05097474 0,08716789 ! protein homotetramerization GO:0051289 21 12 0,000 0,05097474 0,08710598 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05097474 0,08704416 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05097474 0,08698242 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05097474 0,08692078 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05097474 0,08685922 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05097474 0,08679775 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05097474 0,08673636 ! cranial nerve development GO:0021545 20 12 0,000 0,05097474 0,08667506 ! fucose catabolic process GO:0019317 22 12 0,000 0,05097474 0,08661385 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05097474 0,08655273 ! histone methylation GO:0016571 26 12 0,000 0,05097474 0,08649169 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05097474 0,08643074 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05097474 0,08636987 ! gland morphogenesis GO:0022612 29 12 0,000 0,05097474 0,08630909 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,05097474 0,08624839 ! T cell homeostasis GO:0043029 25 12 0,000 0,05097474 0,08618778 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05097474 0,08612726 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05097474 0,08606682 ! spleen development GO:0048536 22 12 0,000 0,05097474 0,08600646 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05097474 0,08594619 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05097474 0,08588601 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05097474 0,0858259 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05097474 0,08576589 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05097474 0,08570595 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,05097474 0,0856461 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05097474 0,08558633 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05097474 0,08552665 ! response to cold GO:0009409 17 12 0,000 0,05097474 0,08546705 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05097474 0,08540753 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05097474 0,0853481 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,0530427 0,08874877 ! response to inorganic substance GO:0010035 153 86 1,000 0,05415495 0,09054678 ! mitochondrion organization GO:0007005 148 86 1,000 0,05415495 0,0904839 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05510436 0,09200631 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05510436 0,0919425 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05510436 0,09187879 ! peroxisomal transport GO:0043574 24 13 0,000 0,05510436 0,09181516 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05510436 0,09175162 ! lipid localization GO:0010876 28 13 0,000 0,05510436 0,09168817 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05510436 0,0916248 ! organelle fusion GO:0048284 32 13 0,000 0,05510436 0,09156153 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05510436 0,09149834 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05510436 0,09143523 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05510436 0,09137222 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05510436 0,09130929 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05510436 0,09124645 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05510436 0,09118369 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05510436 0,09112102 ! methionine metabolic process GO:0006555 27 13 0,000 0,05510436 0,09105844 ! plasma membrane organization GO:0007009 24 13 0,000 0,05510436 0,09099594 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05510436 0,09093353 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05510436 0,09087121 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05510436 0,09080897 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05510436 0,09074681 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05510436 0,09068474 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05510436 0,09062275 ! exocrine system development GO:0035272 32 13 0,000 0,05510436 0,09056085 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05510436 0,09049904 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05510436 0,09043731 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05510436 0,09037566 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05510436 0,09031409 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05510436 0,09025261 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05510436 0,09019122 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05510436 0,09012991 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05510436 0,09006868 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05510436 0,09000753 ! ribosome assembly GO:0042255 17 13 0,000 0,05510436 0,08994647 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05510436 0,08988549 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05510436 0,08982459 ! chromatin silencing GO:0006342 26 13 0,000 0,05510436 0,08976377 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05510436 0,08970304 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05510436 0,08964239 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05510436 0,08958182 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05510436 0,08952133 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05510436 0,08946092 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05510436 0,0894006 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05510436 0,08934036 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05510436 0,0892802 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05510436 0,08922011 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05510436 0,08916011 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05510436 0,0891002 ! embryonic placenta development GO:0001892 23 13 0,000 0,05510436 0,08904036 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05510436 0,0889806 ! insulin secretion GO:0030073 23 13 0,000 0,05510436 0,08892092 ! actin filament polymerization GO:0030041 24 13 0,000 0,05510436 0,08886132 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05510436 0,0888018 ! acrosome reaction GO:0007340 18 13 0,000 0,05510436 0,08874236 ! regulation of protein transport GO:0051223 154 87 1,000 0,05527546 0,08895836 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,05640412 0,09071412 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,05754086 0,0924805 ! ossification GO:0001503 188 90 1,000 0,05868557 0,09425733 ! rRNA transcription GO:0009303 25 14 0,000 0,05921615 0,09504607 ! lactation GO:0007595 26 14 0,000 0,05921615 0,0949827 ! reproductive cellular process GO:0048610 20 14 0,000 0,05921615 0,09491943 ! tRNA modification GO:0006400 20 14 0,000 0,05921615 0,09485623 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05921615 0,09479312 ! regulation of S phase GO:0033261 23 14 0,000 0,05921615 0,09473009 ! water transport GO:0006833 21 14 0,000 0,05921615 0,09466715 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05921615 0,09460429 ! non-recombinational repair GO:0000726 25 14 0,000 0,05921615 0,09454151 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05921615 0,09447882 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05921615 0,09441621 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05921615 0,09435368 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,05921615 0,09429124 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05921615 0,09422887 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05921615 0,09416659 ! palate development GO:0060021 31 14 0,000 0,05921615 0,0941044 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,05921615 0,09404228 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05921615 0,09398025 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,05921615 0,0939183 ! arginine metabolic process GO:0006525 17 14 0,000 0,05921615 0,09385643 ! regulation of heart rate GO:0002027 24 14 0,000 0,05921615 0,09379464 ! organic alcohol transport GO:0015850 29 14 0,000 0,05921615 0,09373293 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,05921615 0,09367131 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,05921615 0,09360976 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05921615 0,0935483 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05921615 0,09348691 ! L-amino acid transport GO:0015807 30 14 0,000 0,05921615 0,09342561 ! bone mineralization GO:0030282 17 14 0,000 0,05921615 0,09336439 ! stem cell development GO:0048864 43 14 0,000 0,05921615 0,09330325 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05921615 0,09324218 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,05921615 0,0931812 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05921615 0,0931203 ! cerebellum development GO:0021549 21 14 0,000 0,05921615 0,09305948 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05921615 0,09299873 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05921615 0,09293807 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05921615 0,09287748 ! cofactor transport GO:0051181 26 14 0,000 0,05921615 0,09281698 ! NADP metabolic process GO:0006739 24 14 0,000 0,05921615 0,09275655 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,05921615 0,0926962 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05921615 0,09263593 ! intestinal absorption GO:0050892 25 14 0,000 0,05921615 0,09257574 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05921615 0,09251562 ! oxygen transport GO:0015671 21 14 0,000 0,05921615 0,09245559 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05921615 0,09239563 ! male genitalia development GO:0030539 24 14 0,000 0,05921615 0,09233575 ! regulation of axon extension GO:0030516 37 14 0,000 0,05921615 0,09227594 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05921615 0,09221622 ! bone development GO:0060348 189 91 1,000 0,05983817 0,09312461 ! regulation of defense response GO:0031347 149 92 1,000 0,06099857 0,09486915 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06331018 0,09840071 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06331018 0,09833719 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,06331018 0,09827374 ! superoxide anion generation GO:0042554 20 15 0,000 0,06331018 0,09821038 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,06331018 0,0981471 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06331018 0,0980839 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06331018 0,09802079 ! copper ion transport GO:0006825 20 15 0,000 0,06331018 0,09795775 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06331018 0,0978948 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06331018 0,09783192 ! sulfate transport GO:0008272 23 15 0,000 0,06331018 0,09776913 ! response to cAMP GO:0051591 22 15 0,000 0,06331018 0,09770642 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06331018 0,09764378 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06331018 0,09758123 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06331018 0,09751876 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,06331018 0,09745637 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06331018 0,09739405 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06331018 0,09733182 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06331018 0,09726967 ! pituitary gland development GO:0021983 29 15 0,000 0,06331018 0,0972076 ! vesicle coating GO:0006901 33 15 0,000 0,06331018 0,0971456 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06331018 0,09708368 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06331018 0,09702185 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06331018 0,09696009 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06331018 0,09689841 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06331018 0,09683681 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06331018 0,09677529 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06331018 0,09671384 ! histone deacetylation GO:0016575 20 15 0,000 0,06331018 0,09665248 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06331018 0,09659119 ! tissue regeneration GO:0042246 26 15 0,000 0,06331018 0,09652998 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06331018 0,09646884 ! water homeostasis GO:0030104 27 15 0,000 0,06331018 0,09640779 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06331018 0,09634681 ! muscle maintenance GO:0046716 26 15 0,000 0,06331018 0,0962859 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06331018 0,09622508 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06331018 0,09616433 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06331018 0,09610366 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06331018 0,09604307 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06331018 0,09598255 ! cell killing GO:0001906 29 15 0,000 0,06331018 0,0959221 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,06331018 0,09586174 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,06331018 0,09580145 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06331018 0,09574123 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06331018 0,09568109 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06331018 0,09562103 ! peptide hormone processing GO:0016486 23 15 0,000 0,06331018 0,09556104 ! forebrain development GO:0030900 188 95 1,000 0,0645257 0,09733469 ! mRNA transport GO:0051028 169 96 1,000 0,06571642 0,09906873 ! regulation of protein localization GO:0032880 176 97 1,000 0,0669145 0,10081171 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06738654 0,10145933 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06738654 0,10139588 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06738654 0,1013325 ! bone remodeling GO:0046849 27 16 0,000 0,06738654 0,10126921 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06738654 0,101206 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06738654 0,10114286 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06738654 0,1010798 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06738654 0,10101683 ! startle response GO:0001964 28 16 0,000 0,06738654 0,10095393 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06738654 0,10089111 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06738654 0,10082836 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06738654 0,1007657 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06738654 0,10070311 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06738654 0,1006406 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06738654 0,10057817 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06738654 0,10051581 ! response to osmotic stress GO:0006970 25 16 0,000 0,06738654 0,10045354 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06738654 0,10039133 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06738654 0,10032921 ! fructose metabolic process GO:0006000 25 16 0,000 0,06738654 0,10026717 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06738654 0,1002052 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06738654 0,1001433 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06738654 0,10008149 ! axon cargo transport GO:0008088 43 16 0,000 0,06738654 0,10001974 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06738654 0,09995808 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06738654 0,09989649 ! DNA replication initiation GO:0006270 27 16 0,000 0,06738654 0,09983498 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06738654 0,09977354 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06738654 0,09971218 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06738654 0,09965089 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,06738654 0,09958968 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06738654 0,09952855 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06738654 0,09946749 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06738654 0,0994065 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06738654 0,09934559 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06738654 0,09928476 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06738654 0,09922399 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,06738654 0,09916331 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,06738654 0,09910269 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,06811987 0,10011998 GO:0016054|organic acid catabolic process, ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,06933242 0,10183993 GO:0060538|skeletal muscle organ development, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07144528 0,10487941 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,07144528 0,10481546 ! metencephalon development GO:0022037 30 17 0,000 0,07144528 0,10475159 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,07144528 0,10468779 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07144528 0,10462407 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07144528 0,10456043 ! signal complex assembly GO:0007172 41 17 0,000 0,07144528 0,10449687 ! endothelial cell migration GO:0043542 28 17 0,000 0,07144528 0,10443339 ! inositol metabolic process GO:0006020 28 17 0,000 0,07144528 0,10436998 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07144528 0,10430665 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07144528 0,10424339 ! glial cell development GO:0021782 27 17 0,000 0,07144528 0,10418021 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07144528 0,10411711 ! adult walking behavior GO:0007628 33 17 0,000 0,07144528 0,10405409 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07144528 0,10399114 ! heart looping GO:0001947 30 17 0,000 0,07144528 0,10392827 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07144528 0,10386547 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,07144528 0,10380275 ! myoblast differentiation GO:0045445 45 17 0,000 0,07144528 0,1037401 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07144528 0,10367753 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,07144528 0,10361504 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,07144528 0,10355262 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07144528 0,10349028 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07144528 0,10342801 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07144528 0,10336582 ! NAD metabolic process GO:0019674 29 17 0,000 0,07144528 0,1033037 ! membrane budding GO:0006900 37 17 0,000 0,07144528 0,10324165 ! DNA integration GO:0015074 29 17 0,000 0,07144528 0,10317968 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,07144528 0,10311779 ! regulation of protein binding GO:0043393 33 17 0,000 0,07144528 0,10305597 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07144528 0,10299422 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07144528 0,10293255 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07144528 0,10287095 ! genitalia development GO:0048806 30 17 0,000 0,07144528 0,10280942 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,07144528 0,10274797 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07144528 0,10268659 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07144528 0,10262529 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,07144528 0,10256405 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,07144528 0,10250289 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07144528 0,10244181 ! steroid catabolic process GO:0006706 31 17 0,000 0,07144528 0,10238079 ! gas transport GO:0015669 25 17 0,000 0,07144528 0,10231985 ! organic cation transport GO:0015695 31 17 0,000 0,07144528 0,10225898 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07144528 0,10219819 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,07144528 0,10213746 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07144528 0,10207681 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07144528 0,10201623 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,07144528 0,10195573 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,0754865 0,10765888 ! neuron maturation GO:0042551 42 18 0,000 0,0754865 0,1075951 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,0754865 0,10753139 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,0754865 0,10746777 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,0754865 0,10740421 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,0754865 0,10734074 ! memory GO:0007613 31 18 0,000 0,0754865 0,10727733 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0754865 0,107214 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,0754865 0,10715075 ! patterning of blood vessels GO:0001569 39 18 0,000 0,0754865 0,10708757 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,0754865 0,10702447 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,0754865 0,10696144 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,0754865 0,10689848 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0754865 0,1068356 ! response to retinoic acid GO:0032526 26 18 0,000 0,0754865 0,10677279 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,0754865 0,10671006 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,0754865 0,1066474 ! response to fungus GO:0009620 21 18 0,000 0,0754865 0,10658481 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,0754865 0,1065223 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,0754865 0,10645986 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,0754865 0,10639749 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,0754865 0,1063352 ! vitamin transport GO:0051180 27 18 0,000 0,0754865 0,10627298 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,0754865 0,10621083 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,0754865 0,10614876 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,0754865 0,10608675 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,0754865 0,10602482 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,0754865 0,10596297 ! nerve development GO:0021675 28 18 0,000 0,0754865 0,10590118 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,0754865 0,10583947 ! protein secretion GO:0009306 39 19 0,000 0,07951027 0,11141625 ! positive regulation of translation GO:0045727 30 19 0,000 0,07951027 0,1113514 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,07951027 0,11128662 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,07951027 0,11122192 ! skin development GO:0043588 36 19 0,000 0,07951027 0,11115729 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,07951027 0,11109274 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07951027 0,11102826 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,07951027 0,11096386 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,07951027 0,11089954 ! bile acid metabolic process GO:0008206 29 19 0,000 0,07951027 0,11083528 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,07951027 0,11077111 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,07951027 0,110707 ! cerebral cortex development GO:0021987 36 19 0,000 0,07951027 0,11064297 ! pigmentation during development GO:0048066 41 19 0,000 0,07951027 0,11057902 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,07951027 0,11051514 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,07951027 0,11045133 ! heme metabolic process GO:0042168 36 19 0,000 0,07951027 0,11038759 ! actin filament bundle formation GO:0051017 42 19 0,000 0,07951027 0,11032393 ! neuromuscular junction development GO:0007528 34 19 0,000 0,07951027 0,11026035 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,07951027 0,11019683 ! plasma membrane fusion GO:0045026 28 19 0,000 0,07951027 0,11013339 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,07951027 0,11007002 ! peptide cross-linking GO:0018149 37 19 0,000 0,07951027 0,11000673 ! protein export from nucleus GO:0006611 36 19 0,000 0,07951027 0,10994351 ! heart process GO:0003015 30 19 0,000 0,07951027 0,10988036 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,07951027 0,10981728 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,07951027 0,10975427 ! visual learning GO:0008542 36 19 0,000 0,07951027 0,10969134 ! cellular pigmentation GO:0033059 36 19 0,000 0,07951027 0,10962848 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,07951027 0,10956569 ! cell-cell junction organization GO:0045216 35 19 0,000 0,07951027 0,10950298 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,07951027 0,10944033 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,07951027 0,10937776 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,07951027 0,10931526 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,07951027 0,10925283 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,07951027 0,10919047 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,07951027 0,10912818 ! cilium assembly GO:0042384 37 19 0,000 0,07951027 0,10906596 ! peptide hormone secretion GO:0030072 31 19 0,000 0,07951027 0,10900382 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08351665 0,11443113 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08351665 0,114366 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08351665 0,11430094 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08351665 0,11423596 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08351665 0,11417106 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08351665 0,11410622 ! response to vitamin GO:0033273 31 20 0,000 0,08351665 0,11404146 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08351665 0,11397678 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08351665 0,11391217 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08351665 0,11384763 ! response to alkaloid GO:0043279 38 20 0,000 0,08351665 0,11378316 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08351665 0,11371877 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,08351665 0,11365445 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08351665 0,1135902 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08351665 0,11352602 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08351665 0,11346192 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08351665 0,11339789 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08351665 0,11333393 ! body fluid secretion GO:0007589 31 20 0,000 0,08351665 0,11327005 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08351665 0,11320623 ! peptide secretion GO:0002790 35 20 0,000 0,08351665 0,11314249 ! stem cell differentiation GO:0048863 53 20 0,000 0,08351665 0,11307882 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08351665 0,11301522 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08351665 0,11295169 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08351665 0,11288824 ! diencephalon development GO:0021536 34 20 0,000 0,08351665 0,11282485 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08351665 0,11276154 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08351665 0,1126983 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08351665 0,11263512 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,08351665 0,11257202 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08351665 0,11250899 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08351665 0,11244603 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08351665 0,11238314 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08351665 0,11232032 ! regulation of glucose import GO:0046324 29 20 0,000 0,08351665 0,11225758 GO:0010827|regulation of glucose transport, ! actin filament-based movement GO:0030048 43 20 0,000 0,08351665 0,1121949 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,08351665 0,11213229 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08351665 0,11206975 ! negative regulation of translation GO:0017148 29 20 0,000 0,08351665 0,11200728 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,08351665 0,11194488 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,08750573 0,1172265 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,08750573 0,11716126 ! hormone secretion GO:0046879 38 21 0,000 0,08750573 0,1170961 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08750573 0,11703101 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,08750573 0,11696599 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08750573 0,11690105 ! axis specification GO:0009798 38 21 0,000 0,08750573 0,11683617 ! ovarian follicle development GO:0001541 35 21 0,000 0,08750573 0,11677137 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,08750573 0,11670664 ! smooth muscle contraction GO:0006939 46 21 0,000 0,08750573 0,11664199 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,08750573 0,1165774 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,08750573 0,11651289 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,08750573 0,11644844 ! cytolysis GO:0019835 24 21 0,000 0,08750573 0,11638407 ! vasodilation GO:0042311 39 21 0,000 0,08750573 0,11631977 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08750573 0,11625554 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08750573 0,11619138 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08750573 0,11612729 ! oogenesis GO:0048477 36 21 0,000 0,08750573 0,11606328 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,08750573 0,11599933 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,08750573 0,11593545 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,08750573 0,11587165 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,08750573 0,11580791 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,08750573 0,11574425 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08750573 0,11568065 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,08750573 0,11561713 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,08750573 0,11555367 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,08750573 0,11549028 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,08750573 0,11542697 ! collagen catabolic process GO:0030574 28 21 0,000 0,08750573 0,11536372 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08750573 0,11530054 ! gut development GO:0048565 39 21 0,000 0,08750573 0,11523743 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,09147758 0,12040211 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09147758 0,12033628 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09147758 0,12027052 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09147758 0,12020483 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,09147758 0,12013922 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,09147758 0,12007368 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09147758 0,12000821 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,09147758 0,11994281 ! regeneration GO:0031099 41 22 0,000 0,09147758 0,11987748 ! keratinization GO:0031424 28 22 0,000 0,09147758 0,11981222 ! sensory perception of taste GO:0050909 28 22 0,000 0,09147758 0,11974704 ! vacuolar transport GO:0007034 36 22 0,000 0,09147758 0,11968192 ! lysosome organization GO:0007040 41 22 0,000 0,09147758 0,11961688 ! central nervous system neuron development GO:0021954 46 22 0,000 0,09147758 0,1195519 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,09147758 0,119487 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,09147758 0,11942217 ! fucose metabolic process GO:0006004 39 22 0,000 0,09147758 0,1193574 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09147758 0,11929271 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,09147758 0,11922809 ! ureteric bud development GO:0001657 43 22 0,000 0,09147758 0,11916354 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09147758 0,11909905 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,09147758 0,11903464 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,09147758 0,1189703 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,09147758 0,11890603 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09147758 0,11884182 ! sarcomere organization GO:0045214 30 22 0,000 0,09147758 0,11877769 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,09147758 0,11871362 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09147758 0,11864962 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,09147758 0,1185857 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,09147758 0,11852184 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,09147758 0,11845805 ! protein stabilization GO:0050821 39 22 0,000 0,09147758 0,11839433 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,09543227 0,12344626 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,09543227 0,12337992 ! gluconeogenesis GO:0006094 33 23 0,000 0,09543227 0,12331366 ! viral genome replication GO:0019079 41 23 0,000 0,09543227 0,12324747 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09543227 0,12318135 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09543227 0,1231153 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09543227 0,12304932 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09543227 0,12298342 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,09543227 0,12291758 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09543227 0,12285181 ! visual behavior GO:0007632 42 23 0,000 0,09543227 0,12278612 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,09543227 0,12272049 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,09543227 0,12265494 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09543227 0,12258945 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,09543227 0,12252403 ! peroxisome organization GO:0007031 37 23 0,000 0,09543227 0,12245869 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09543227 0,12239341 ! vesicle targeting GO:0006903 43 23 0,000 0,09543227 0,1223282 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,09543227 0,12226307 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09543227 0,122198 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09543227 0,122133 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09543227 0,12206807 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09543227 0,12200321 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09543227 0,12193842 ! fatty acid transport GO:0015908 44 23 0,000 0,09543227 0,12187369 ! platelet activation GO:0030168 37 23 0,000 0,09543227 0,12180904 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09543227 0,12174445 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09543227 0,12167994 ! hormone transport GO:0009914 40 23 0,000 0,09543227 0,12161549 ! cell-cell recognition GO:0009988 25 23 0,000 0,09543227 0,12155111 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09543227 0,12148679 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09543227 0,12142255 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,09543227 0,12135837 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09543227 0,12129426 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,09543227 0,12123022 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,09936988 0,12616566 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,09936988 0,12609912 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,09936988 0,12603264 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,09936988 0,12596624 ! vesicle docking GO:0048278 47 24 0,000 0,09936988 0,12589991 ! spinal cord development GO:0021510 47 24 0,000 0,09936988 0,12583364 ! vacuole organization GO:0007033 43 24 0,000 0,09936988 0,12576745 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,09936988 0,12570133 ! digestive system process GO:0022600 39 24 0,000 0,09936988 0,12563527 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,09936988 0,12556929 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,09936988 0,12550337 ! regulation of behavior GO:0050795 43 24 0,000 0,09936988 0,12543753 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,09936988 0,12537175 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,09936988 0,12530604 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,09936988 0,1252404 ! membrane depolarization GO:0051899 39 24 0,000 0,09936988 0,12517483 ! pentose metabolic process GO:0019321 35 24 0,000 0,09936988 0,12510933 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,09936988 0,12504389 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,09936988 0,12497853 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,09936988 0,12491323 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,09936988 0,124848 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,09936988 0,12478284 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,09936988 0,12471775 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,09936988 0,12465272 ! regulation of amine transport GO:0051952 40 24 0,000 0,09936988 0,12458777 ! myelination GO:0042552 45 25 0,000 0,10329047 0,12943588 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10329047 0,1293685 ! phototransduction GO:0007602 33 25 0,000 0,10329047 0,12930119 ! vasculogenesis GO:0001570 46 25 0,000 0,10329047 0,12923395 ! sperm motility GO:0030317 31 25 0,000 0,10329047 0,12916678 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,10329047 0,12909968 ! receptor metabolic process GO:0043112 46 25 0,000 0,10329047 0,12903265 ! chromosome condensation GO:0030261 45 25 0,000 0,10329047 0,12896569 ! osteoblast differentiation GO:0001649 60 25 0,000 0,10329047 0,1288988 ! neural crest cell development GO:0014032 54 25 0,000 0,10329047 0,12883198 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10329047 0,12876522 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,10329047 0,12869854 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10329047 0,12863193 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10329047 0,12856538 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,10329047 0,12849891 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10329047 0,1284325 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,10329047 0,12836616 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10329047 0,12829989 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10329047 0,12823369 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,10329047 0,12816755 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10329047 0,12810149 ! telomere organization GO:0032200 43 25 0,000 0,10329047 0,12803549 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10329047 0,12796956 GO:0060606|tube closure, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,10719414 0,13273757 ! embryonic pattern specification GO:0009880 44 26 0,000 0,10719414 0,13266928 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,10719414 0,13260107 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,10719414 0,13253293 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,10719414 0,13246486 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,10719414 0,13239686 ! molting cycle process GO:0022404 50 26 0,000 0,10719414 0,13232893 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,10719414 0,13226107 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,10719414 0,13219328 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,10719414 0,13212556 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,10719414 0,13205791 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,10719414 0,13199032 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,10719414 0,13192281 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,10719414 0,13185536 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,10719414 0,13178799 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,10719414 0,13172068 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,10719414 0,13165344 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,10719414 0,13158627 ! blastocyst development GO:0001824 49 26 0,000 0,10719414 0,13151917 ! leukocyte proliferation GO:0070661 52 26 0,000 0,10719414 0,13145214 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,10719414 0,13138517 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,10719414 0,13131827 ! neuron fate commitment GO:0048663 48 27 0,000 0,11108093 0,13601054 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,11108093 0,13594136 ! iron ion transport GO:0006826 59 27 0,000 0,11108093 0,13587225 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,11108093 0,13580321 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,11108093 0,13573424 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,11108093 0,13566534 ! fat cell differentiation GO:0045444 50 27 0,000 0,11108093 0,13559651 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,11108093 0,13552775 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,11108093 0,13545906 ! male gonad development GO:0008584 44 27 0,000 0,11108093 0,13539044 ! response to toxin GO:0009636 47 27 0,000 0,11108093 0,13532188 ! primary neural tube formation GO:0014020 51 27 0,000 0,11108093 0,1352534 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,11108093 0,13518499 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,11108093 0,13511664 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,11108093 0,13504837 ! glutathione metabolic process GO:0006749 39 27 0,000 0,11108093 0,13498016 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,11108093 0,13491202 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,11108093 0,13484396 ! circadian rhythm GO:0007623 50 28 0,000 0,11495093 0,13947148 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,11495093 0,13940118 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,11495093 0,13933096 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,11495093 0,1392608 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,11495093 0,13919071 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,11495093 0,1391207 ! synaptogenesis GO:0007416 42 28 0,000 0,11495093 0,13905075 ! lipid oxidation GO:0034440 43 28 0,000 0,11495093 0,13898088 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,11495093 0,13891107 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,11495093 0,13884134 ! translational initiation GO:0006413 65 29 0,000 0,11880422 0,14342346 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,11880422 0,14335153 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,11880422 0,14327967 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,11880422 0,14320789 ! catechol metabolic process GO:0009712 54 29 0,000 0,11880422 0,14313618 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,11880422 0,14306454 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,11880422 0,14299297 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,11880422 0,14292147 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,11880422 0,14285005 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,11880422 0,14277869 ! cell fate determination GO:0001709 60 29 0,000 0,11880422 0,14270741 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,11880422 0,1426362 ! detection of light stimulus GO:0009583 38 29 0,000 0,11880422 0,14256506 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,11880422 0,14249399 ! tissue homeostasis GO:0001894 48 29 0,000 0,11880422 0,14242299 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,11880422 0,14235206 ! phenol metabolic process GO:0018958 55 30 0,000 0,12264085 0,146876 ! zinc ion transport GO:0006829 45 30 0,000 0,12264085 0,14680293 ! membrane docking GO:0022406 61 30 0,000 0,12264085 0,14672993 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,12264085 0,146657 ! cell junction assembly GO:0034329 78 30 0,000 0,12264085 0,14658415 ! regulation of innate immune response GO:0045088 51 30 0,000 0,12264085 0,14651136 ! acute-phase response GO:0006953 49 30 0,000 0,12264085 0,14643865 ! myofibril assembly GO:0030239 47 30 0,000 0,12264085 0,14636602 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,12264085 0,14629345 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,12264085 0,14622096 ! phospholipid transport GO:0015914 51 30 0,000 0,12264085 0,14614853 ! ensheathment of neurons GO:0007272 57 30 0,000 0,12264085 0,14607618 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,12264085 0,1460039 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,12264085 0,1459317 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,12264085 0,14585956 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,12264085 0,14578749 ! eye morphogenesis GO:0048592 60 30 0,000 0,12264085 0,1457155 ! response to heat GO:0009408 50 30 0,000 0,12264085 0,14564358 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,12646091 0,15010604 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,12646091 0,15003202 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,12646091 0,14995808 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,12646091 0,14988421 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,12646091 0,14981041 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,12646091 0,14973669 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,12646091 0,14966303 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,12646091 0,14958945 ! ovulation cycle process GO:0022602 49 31 0,000 0,12646091 0,14951594 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,12646091 0,14944251 ! peptide transport GO:0015833 55 31 0,000 0,12646091 0,14936914 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,12646091 0,14929585 ! iron ion homeostasis GO:0055072 54 31 0,000 0,12646091 0,14922263 ! mesoderm formation GO:0001707 69 31 0,000 0,12646091 0,14914948 ! natural killer cell activation GO:0030101 45 31 0,000 0,12646091 0,14907641 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,12646091 0,1490034 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,12646091 0,14893047 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,12646091 0,1488576 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,13026446 0,1532598 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,13026446 0,15318489 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,13026446 0,15311006 ! cholesterol transport GO:0030301 56 32 0,000 0,13026446 0,1530353 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,13026446 0,15296061 ! spliceosome assembly GO:0000245 67 32 0,000 0,13026446 0,15288599 ! spindle organization GO:0007051 46 32 0,000 0,13026446 0,15281145 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,13026446 0,15273698 ! metanephros development GO:0001656 74 32 0,000 0,13026446 0,15266258 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,13026446 0,15258826 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,13026446 0,15251401 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,13026446 0,15243983 ! muscle cell development GO:0055001 49 32 0,000 0,13026446 0,15236572 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,13026446 0,15229168 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,13026446 0,15221772 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,13026446 0,15214383 ! ovulation cycle GO:0042698 51 32 0,000 0,13026446 0,15207001 ! peripheral nervous system development GO:0007422 64 32 0,000 0,13026446 0,15199626 ! BMP signaling pathway GO:0030509 64 32 0,000 0,13026446 0,15192258 ! hindbrain development GO:0030902 61 32 0,000 0,13026446 0,15184898 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,13026446 0,15177544 ! gene silencing GO:0016458 65 32 0,000 0,13026446 0,15170198 ! post-embryonic development GO:0009791 69 33 0,000 0,13405157 0,15603681 ! protein targeting to membrane GO:0006612 68 33 0,000 0,13405157 0,15596136 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,13405157 0,15588598 ! ceramide metabolic process GO:0006672 64 33 0,000 0,13405157 0,15581067 ! formation of primary germ layer GO:0001704 72 33 0,000 0,13405157 0,15573543 ! cell fate specification GO:0001708 52 33 0,000 0,13405157 0,15566027 ! sterol transport GO:0015918 57 33 0,000 0,13405157 0,15558518 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,13405157 0,15551017 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,13405157 0,15543522 ! adult locomotory behavior GO:0008344 59 33 0,000 0,13405157 0,15536035 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,13405157 0,15528555 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,13405157 0,15521082 ! glial cell differentiation GO:0010001 63 34 0,000 0,13782232 0,1595 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,13782232 0,15942332 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,13782232 0,15934671 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,13782232 0,15927018 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,13782232 0,15919372 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,13782232 0,15911733 ! mismatch repair GO:0006298 46 34 0,000 0,13782232 0,15904101 ! spermatid development GO:0007286 63 34 0,000 0,13782232 0,15896477 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,13782232 0,1588886 ! placenta development GO:0001890 53 34 0,000 0,13782232 0,1588125 ! regulation of muscle development GO:0048634 70 35 0,000 0,14157678 0,16306067 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,14157678 0,16298265 ! negative regulation of secretion GO:0051048 63 35 0,000 0,14157678 0,1629047 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,14157678 0,16282683 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,14157678 0,16274903 ! odontogenesis GO:0042476 66 35 0,000 0,14157678 0,16267131 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,14157678 0,16259367 ! female gonad development GO:0008585 58 35 0,000 0,14157678 0,16251609 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,14157678 0,16243859 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,14157678 0,16236117 ! neural tube formation GO:0001841 67 35 0,000 0,14157678 0,16228382 ! vesicle localization GO:0051648 64 35 0,000 0,14157678 0,16220654 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,14531501 0,16641024 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,14531501 0,16633107 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,14531501 0,16625198 ! cell junction organization GO:0034330 86 36 0,000 0,14531501 0,16617296 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,14531501 0,16609402 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,14531501 0,16601515 ! positive regulation of cell development GO:0010720 80 36 0,000 0,14531501 0,16593636 ! regulation of proteolysis GO:0030162 72 36 0,000 0,14531501 0,16585764 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,14531501 0,165779 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,14531501 0,16570043 ! aerobic respiration GO:0009060 55 36 0,000 0,14531501 0,16562194 ! embryonic organ development GO:0048568 57 36 0,000 0,14531501 0,16554352 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,14531501 0,16546517 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,14531501 0,1653869 ! RNA export from nucleus GO:0006405 56 37 0,000 0,14903708 0,1695429 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,14903708 0,16946277 ! meiosis I GO:0007127 65 37 0,000 0,14903708 0,16938272 ! sister chromatid segregation GO:0000819 58 37 0,000 0,14903708 0,16930275 ! actomyosin structure organization GO:0031032 62 37 0,000 0,14903708 0,16922285 ! organic anion transport GO:0015711 68 37 0,000 0,14903708 0,16914303 ! tissue remodeling GO:0048771 76 37 0,000 0,14903708 0,16906328 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,14903708 0,16898361 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,14903708 0,16890401 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,14903708 0,16882449 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,14903708 0,16874505 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,14903708 0,16866567 ! glycogen metabolic process GO:0005977 61 37 0,000 0,14903708 0,16858638 ! pigment metabolic process GO:0042440 80 37 0,000 0,14903708 0,16850715 ! spermatid differentiation GO:0048515 66 37 0,000 0,14903708 0,16842801 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,15274307 0,17253513 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,15274307 0,17245417 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,15274307 0,17237328 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,15274307 0,17229247 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,15274307 0,17221173 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,15274307 0,17213107 ! lipid homeostasis GO:0055088 67 38 0,000 0,15274307 0,17205048 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,15274307 0,17196997 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,15274307 0,17188954 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,15274307 0,17180918 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,15274307 0,17172889 ! glucan metabolic process GO:0044042 62 38 0,000 0,15274307 0,17164868 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 0,000 0,15643304 0,17571331 ! learning GO:0007612 77 39 0,000 0,15643304 0,17563131 ! ear morphogenesis GO:0042471 60 39 0,000 0,15643304 0,1755494 ! organic ether metabolic process GO:0018904 55 39 0,000 0,15643304 0,17546755 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,15643304 0,17538579 ! ion transmembrane transport GO:0034220 66 39 0,000 0,15643304 0,1753041 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,15643304 0,17522249 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,15643304 0,17514095 ! RNA modification GO:0009451 57 39 0,000 0,15643304 0,17505949 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,15643304 0,17497811 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,16010707 0,17900446 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,16010707 0,17892132 ! feeding behavior GO:0007631 59 40 0,000 0,16010707 0,17883826 ! negative regulation of binding GO:0051100 72 40 0,000 0,16010707 0,17875527 ! mesenchymal cell development GO:0014031 87 40 0,000 0,16010707 0,17867236 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 0,000 0,16010707 0,17858952 ! cytokinesis GO:0000910 72 40 0,000 0,16010707 0,17850677 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,16376521 0,18250074 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,16376521 0,18241625 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,16376521 0,18233184 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,16376521 0,1822475 ! female gamete generation GO:0007292 61 41 0,000 0,16376521 0,18216324 ! polyol metabolic process GO:0019751 66 41 0,000 0,16376521 0,18207907 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,16376521 0,18199496 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,16740754 0,18595685 ! regulation of tube size GO:0035150 71 42 0,000 0,16740754 0,18587104 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,16740754 0,18578531 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,16740754 0,18569965 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,16740754 0,18561408 ! regulation of protein secretion GO:0050708 71 42 0,000 0,16740754 0,18552858 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,17103413 0,18946046 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,17103413 0,18937327 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,17103413 0,18928616 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,17103413 0,18919913 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,17103413 0,18911219 ! glucose transport GO:0015758 65 43 0,000 0,17103413 0,18902532 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,17103413 0,18893853 ! neural tube development GO:0021915 77 43 0,000 0,17103413 0,18885182 ! striated muscle contraction GO:0006941 77 43 0,000 0,17103413 0,18876519 ! phagocytosis GO:0006909 90 43 0,000 0,17103413 0,18867864 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,17103413 0,18859217 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,17464504 0,19248555 ! hexose transport GO:0008645 67 44 0,000 0,17464504 0,19239742 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,17464504 0,19230937 ! male sex differentiation GO:0046661 76 44 0,000 0,17464504 0,19222139 ! developmental growth GO:0048589 82 44 0,000 0,17464504 0,1921335 ! maintenance of location in cell GO:0051651 97 44 0,000 0,17464504 0,19204569 ! glycolysis GO:0006096 65 45 0,000 0,17824034 0,19590967 ! leukocyte migration GO:0050900 68 45 0,000 0,17824034 0,19582021 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,17824034 0,19573084 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,17824034 0,19564154 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,17824034 0,19555233 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,17824034 0,1954632 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,17824034 0,19537415 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,17824034 0,19528518 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,17824034 0,1951963 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,1818201 0,19902601 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,1818201 0,1989355 ! pigmentation GO:0043473 100 46 0,000 0,1818201 0,19884507 ! positive regulation of defense response GO:0031349 76 47 0,000 0,18538438 0,20265099 ! response to calcium ion GO:0051592 81 47 0,000 0,18538438 0,20255896 ! endosome transport GO:0016197 108 47 0,000 0,18538438 0,20246701 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,18538438 0,20237515 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,18538438 0,20228337 ! JNK cascade GO:0007254 91 47 0,000 0,18538438 0,20219167 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,18538438 0,20210006 ! Notch signaling pathway GO:0007219 96 48 0,000 0,18893326 0,20587564 ! cellular component disassembly GO:0022411 86 48 0,000 0,18893326 0,20578244 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,18893326 0,20568933 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,18893326 0,2055963 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,18893326 0,20550335 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,18893326 0,20541049 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,19246679 0,20915768 ! regulation of action potential GO:0001508 95 49 0,000 0,19246679 0,20906325 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,19246679 0,20896891 ! regulation of ion transport GO:0043269 77 49 0,000 0,19246679 0,20887465 ! peptide metabolic process GO:0006518 76 49 0,000 0,19246679 0,20878048 ! response to temperature stimulus GO:0009266 76 49 0,000 0,19246679 0,20868639 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,19246679 0,20859238 ! endocrine system development GO:0035270 104 49 0,000 0,19246679 0,20849847 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,19246679 0,20840463 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,19246679 0,20831088 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,19246679 0,20821722 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,19246679 0,20812364 ! neuromuscular process GO:0050905 99 50 0,000 0,19598504 0,21183289 ! regulation of ossification GO:0030278 117 50 0,000 0,19598504 0,21173777 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,19598504 0,21164273 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,19948808 0,215329 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,19948808 0,21523244 ! excretion GO:0007588 83 51 0,000 0,19948808 0,21513596 ! chromatin remodeling GO:0006338 109 51 0,000 0,19948808 0,21503958 ! regulation of cell shape GO:0008360 125 51 0,000 0,19948808 0,21494327 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,19948808 0,21484706 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,20297598 0,21850569 ! membrane fusion GO:0006944 110 52 0,000 0,20297598 0,21840796 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,20297598 0,21831033 ! amino acid activation GO:0043038 92 52 0,000 0,20297598 0,21821278 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,20297598 0,21811532 ! synapse organization GO:0050808 85 52 0,000 0,20297598 0,21801795 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,20644879 0,22164917 ! regulation of translational initiation GO:0006446 82 53 0,000 0,20644879 0,22155031 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,20644879 0,22145154 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,20644879 0,22135285 ! cell maturation GO:0048469 100 53 0,000 0,20644879 0,22125425 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,20990659 0,22485987 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,20990659 0,22475979 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,20990659 0,22465981 ! chloride transport GO:0006821 90 55 0,000 0,21334944 0,2282431 ! glucose catabolic process GO:0006007 82 55 0,000 0,21334944 0,22814166 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,21334944 0,22804031 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,21334944 0,22793905 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,21334944 0,22783788 ! gastrulation GO:0007369 112 55 0,000 0,21334944 0,2277368 ! nuclear export GO:0051168 97 55 0,000 0,21334944 0,22763581 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,21334944 0,2275349 ! sensory perception of smell GO:0007608 80 56 0,000 0,21677739 0,23108835 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,21677739 0,23098601 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,21677739 0,23088376 ! proton transport GO:0015992 94 56 0,000 0,21677739 0,23078159 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,22019052 0,23431154 ! muscle fiber development GO:0048747 112 57 0,000 0,22019052 0,23420796 ! maintenance of location GO:0051235 118 57 0,000 0,22019052 0,23410446 ! hydrogen transport GO:0006818 97 58 0,000 0,22358889 0,23761258 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,22358889 0,23750767 ! regulation of endocytosis GO:0030100 91 58 0,000 0,22358889 0,23740286 ! adult behavior GO:0030534 99 58 0,000 0,22358889 0,23729814 ! positive regulation of secretion GO:0051047 95 59 0,000 0,22697257 0,24078307 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,22697257 0,24067695 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,22697257 0,24057093 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,22697257 0,24046499 ! DNA catabolic process GO:0006308 86 59 0,000 0,22697257 0,24035916 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,22697257 0,24025341 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,23034161 0,24371236 ! regulation of heart contraction GO:0008016 110 60 0,000 0,23034161 0,24360524 ! camera-type eye development GO:0043010 116 60 0,000 0,23034161 0,2434982 ! kidney development GO:0001822 122 60 0,000 0,23034161 0,24339126 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,23369608 0,24682738 ! mesoderm development GO:0007498 119 61 0,000 0,23369608 0,24671907 ! tRNA processing GO:0008033 89 61 0,000 0,23369608 0,24661086 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,23369608 0,24650274 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,23703604 0,24991617 ! gonad development GO:0008406 98 62 0,000 0,23703604 0,2498067 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,23703604 0,24969733 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,24036155 0,25308967 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,24367268 0,25646389 ! cell redox homeostasis GO:0045454 102 64 0,000 0,24367268 0,25635175 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,24367268 0,25623971 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,24367268 0,25612777 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,24367268 0,25601592 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,24696948 0,25936647 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,24696948 0,2592533 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,24696948 0,25914024 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,24696948 0,25902728 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,25025202 0,26235572 ! actin filament organization GO:0007015 148 66 0,000 0,25025202 0,26224145 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,25025202 0,26212728 ! extracellular matrix organization GO:0030198 133 66 0,000 0,25025202 0,26201322 ! secondary metabolic process GO:0019748 116 66 0,000 0,25025202 0,26189925 ! developmental maturation GO:0021700 116 66 0,000 0,25025202 0,26178538 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,25352037 0,26508909 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,25352037 0,26497394 ! hexose catabolic process GO:0019320 104 67 0,000 0,25352037 0,26485888 ! adaptive immune response GO:0002250 119 67 0,000 0,25352037 0,26474393 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,25352037 0,26462907 ! amino acid transport GO:0006865 125 68 0,000 0,25677457 0,26790964 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,25677457 0,26779351 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,25677457 0,26767748 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,25677457 0,26756155 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,25677457 0,26744572 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,2600147 0,27070332 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,2600147 0,27058623 ! urogenital system development GO:0001655 137 69 0,000 0,2600147 0,27046924 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,2600147 0,27035236 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,2600147 0,27023558 ! appendage morphogenesis GO:0035107 135 70 0,000 0,2632408 0,27347037 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 0,000 0,26645295 0,27668788 ! appendage development GO:0048736 136 71 0,000 0,26645295 0,27656851 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,26645295 0,27644925 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,26645295 0,27633009 ! acute inflammatory response GO:0002526 113 72 0,000 0,26965121 0,27952641 ! carbohydrate transport GO:0008643 110 72 0,000 0,26965121 0,27940603 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,26965121 0,27928575 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,26965121 0,27916558 ! learning or memory GO:0007611 147 73 0,000 0,27283562 0,28234086 ! regulation of blood pressure GO:0008217 125 73 0,000 0,27283562 0,28221948 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,27283562 0,28209819 ! axon guidance GO:0007411 139 73 0,000 0,27283562 0,28197702 ! fertilization GO:0009566 90 73 0,000 0,27283562 0,28185595 ! transition metal ion transport GO:0000041 126 74 0,000 0,27600625 0,28500903 ! neurotransmitter transport GO:0006836 123 74 0,000 0,27600625 0,28488676 ! meiosis GO:0007126 121 74 0,000 0,27600625 0,2847646 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,27600625 0,28464254 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,27600625 0,28452058 ! eye development GO:0001654 143 74 0,000 0,27600625 0,28439873 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,27916317 0,2875285 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,27916317 0,28740547 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,27916317 0,28728254 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,27916317 0,28715972 ! meiotic cell cycle GO:0051321 122 75 0,000 0,27916317 0,287037 ! rhythmic process GO:0048511 128 75 0,000 0,27916317 0,28691439 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,28230642 0,29002103 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,28230642 0,28989725 ! defense response to bacterium GO:0042742 89 76 0,000 0,28230642 0,28977357 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,28230642 0,28965 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,28543607 0,29273623 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,28543607 0,2926115 ! blood coagulation GO:0007596 146 78 0,000 0,28855218 0,29567996 GO:0050817|coagulation, ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,2916548 0,29873199 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,2916548 0,29860487 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,2916548 0,29847786 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,294744 0,30151108 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,294744 0,30138294 ! inorganic anion transport GO:0015698 138 80 0,000 0,294744 0,30125491 ! digestion GO:0007586 112 81 0,000 0,29781982 0,30426942 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,29781982 0,30414028 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,30088233 0,30713742 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,30088233 0,30700716 ! response to nutrient GO:0007584 125 82 0,000 0,30088233 0,30687702 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,30088233 0,30674699 ! regulation of lyase activity GO:0051339 160 83 0,000 0,30393159 0,30972444 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,30696765 0,31268593 ! hemostasis GO:0007599 158 84 0,000 0,30696765 0,3125536 ! negative regulation of transport GO:0051051 153 84 0,000 0,30696765 0,31242139 ! regulation of ligase activity GO:0051340 142 84 0,000 0,30696765 0,31228929 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,30696765 0,31215729 ! response to unfolded protein GO:0006986 131 85 0,000 0,30999056 0,31509814 ! nucleosome assembly GO:0006334 122 85 0,000 0,30999056 0,31496507 ! amine biosynthetic process GO:0009309 138 86 0,000 0,31300039 0,31788896 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,31300039 0,31775483 ! chromatin assembly GO:0031497 124 86 0,000 0,31300039 0,31762081 ! tube morphogenesis GO:0035239 176 86 0,000 0,31300039 0,31748691 ! alcohol catabolic process GO:0046164 130 86 0,000 0,31300039 0,31735312 ! amine transport GO:0015837 155 86 0,000 0,31300039 0,31721944 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,3159972 0,32012179 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,31898102 0,32300856 ! gland development GO:0048732 206 88 0,000 0,31898102 0,32287267 ! regulation of neurological system process GO:0031644 148 88 0,000 0,31898102 0,3227369 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,31898102 0,32260124 ! cellular defense response GO:0006968 114 89 0,000 0,32195193 0,32546906 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,32195193 0,32533236 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,32490998 0,32818364 ! sex differentiation GO:0007548 145 90 0,000 0,32490998 0,32804592 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,32490998 0,32790831 ! sterol metabolic process GO:0016125 152 91 0,000 0,32785523 0,330742 ! response to protein stimulus GO:0051789 149 91 0,000 0,32785523 0,33060338 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,32785523 0,33046488 ! nucleosome organization GO:0034728 138 92 0,000 0,33078772 0,33328109 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,33078772 0,33314159 ! vitamin metabolic process GO:0006766 139 92 0,000 0,33078772 0,3330022 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,33370751 0,33580103 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,33370751 0,33566065 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,33370751 0,33552038 ! regulation of membrane potential GO:0042391 164 93 0,000 0,33370751 0,33538023 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,33370751 0,3352402 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,33661466 0,33801956 ! female pregnancy GO:0007565 164 94 0,000 0,33661466 0,33787855 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,33950923 0,34064187 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,34239126 0,34339031 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,34239126 0,34324723 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,3452608 0,3459798 ! protein ubiquitination GO:0016567 217 97 0,000 0,3452608 0,34583576 ! hormone metabolic process GO:0042445 157 97 0,000 0,3452608 0,34569184 ! response to virus GO:0009615 160 98 0,000 0,34811793 0,34840754 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,34811793 0,34826268 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,35096268 0,35096268