pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1152-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of positive chemotaxis GO:0050930 14 8 3,000 3,421E-08 7,869E-05 ! insulin receptor signaling pathway GO:0008286 40 24 4,000 8,981E-08 1,033E-04 ! filopodium assembly GO:0046847 19 11 3,000 1,595E-07 1,223E-04 ! regulation of positive chemotaxis GO:0050926 17 11 3,000 1,595E-07 9,172E-05 GO:0050927|positive regulation of positive chemotaxis, ! microspike assembly GO:0030035 23 12 3,000 2,384E-07 1,097E-04 ! cellular response to insulin stimulus GO:0032869 52 34 4,000 5,662E-07 2,171E-04 ! positive regulation of glycolysis GO:0045821 11 5 2,000 1,063E-06 3,492E-04 ! nuclear migration GO:0007097 10 5 2,000 1,063E-06 3,056E-04 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 1,063E-06 2,716E-04 GO:0031272|regulation of pseudopodium assembly, ! response to insulin stimulus GO:0032868 63 43 4,000 1,894E-06 4,355E-04 ! macrophage differentiation GO:0030225 10 6 2,000 2,118E-06 4,429E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 2,000 2,118E-06 4,06E-04 ! positive regulation of locomotion GO:0040017 35 20 3,000 2,266E-06 4,009E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 36 21 3,000 2,789E-06 4,582E-04 ! regulation of behavior GO:0050795 38 22 3,000 3,396E-06 5,208E-04 ! regulation of lipid kinase activity GO:0043550 12 7 2,000 3,694E-06 5,31E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 3,694E-06 4,998E-04 ! establishment of nucleus localization GO:0040023 13 7 2,000 3,694E-06 4,72E-04 ! negative regulation of phosphorylation GO:0042326 41 23 3,000 4,096E-06 4,959E-04 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 3,000 5,809E-06 6,68E-04 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 2,000 5,89E-06 6,451E-04 ! response to peptide hormone stimulus GO:0043434 84 57 4,000 7,814E-06 8,169E-04 ! positive regulation of glucose metabolic process GO:0010907 15 9 2,000 8,804E-06 8,804E-04 ! regulation of glycolysis GO:0006110 15 9 2,000 8,804E-06 8,437E-04 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 8,804E-06 8,1E-04 ! nucleus localization GO:0051647 15 9 2,000 8,804E-06 7,788E-04 ! regulation of cell projection assembly GO:0060491 20 10 2,000 1,253E-05 1,068E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 2,000 1,253E-05 1,03E-03 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 18 11 2,000 1,717E-05 1,362E-03 ! chondrocyte differentiation GO:0002062 17 11 2,000 1,717E-05 1,317E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 1,717E-05 1,274E-03 GO:0010829|negative regulation of glucose transport, ! positive regulation of cellular catabolic process GO:0031331 22 12 2,000 2,282E-05 1,64E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 2,000 2,282E-05 1,59E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cellular response to hormone stimulus GO:0032870 109 74 4,000 2,82E-05 1,908E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 2,956E-05 1,943E-03 ! positive regulation of response to external stimulus GO:0032103 65 40 3,000 3,973E-05 2,538E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 3,000 3,973E-05 2,47E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 4,67E-05 2,827E-03 ! regulation of glucose metabolic process GO:0010906 22 16 2,000 5,728E-05 3,378E-03 ! neutrophil chemotaxis GO:0030593 21 16 2,000 5,728E-05 3,294E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 2,000 5,728E-05 3,213E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 6,932E-05 3,796E-03 ! response to retinoic acid GO:0032526 25 18 2,000 8,289E-05 4,434E-03 ! regulation of glucose import GO:0046324 21 18 2,000 8,289E-05 4,333E-03 GO:0010827|regulation of glucose transport, ! regulation of angiogenesis GO:0045765 94 49 3,000 8,912E-05 4,555E-03 ! cartilage development GO:0051216 70 49 3,000 8,912E-05 4,456E-03 ! regulation of carbohydrate metabolic process GO:0006109 28 19 2,000 9,809E-05 4,8E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to vitamin A GO:0033189 26 19 2,000 9,809E-05 4,7E-03 ! positive regulation of cell migration GO:0030335 92 51 3,000 1,044E-04 4,898E-03 ! response to vitamin GO:0033273 29 20 2,000 1,15E-04 5,29E-03 ! positive regulation of inflammatory response GO:0050729 30 20 2,000 1,15E-04 5,186E-03 ! cell projection assembly GO:0030031 76 53 3,000 1,214E-04 5,369E-03 ! myeloid leukocyte differentiation GO:0002573 33 21 2,000 1,337E-04 5,802E-03 ! positive regulation of cell motion GO:0051272 99 56 3,000 1,506E-04 6,415E-03 ! vasculogenesis GO:0001570 33 22 2,000 1,543E-04 6,452E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 1,614E-04 6,628E-03 ! negative regulation of kinase activity GO:0033673 100 58 3,000 1,727E-04 6,969E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 2,000 1,768E-04 7,011E-03 ! lung development GO:0030324 94 59 3,000 1,846E-04 7,196E-03 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 2,014E-04 7,719E-03 ! regulation of cellular catabolic process GO:0031329 36 24 2,000 2,014E-04 7,593E-03 ! regulation of endothelial cell proliferation GO:0001936 46 24 2,000 2,014E-04 7,47E-03 ! negative regulation of transferase activity GO:0051348 105 61 3,000 2,101E-04 7,671E-03 ! respiratory tube development GO:0030323 99 62 3,000 2,238E-04 8,042E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,26E-04 7,997E-03 ! regulation of hormone biosynthetic process GO:0046885 7 5 1,000 2,26E-04 7,876E-03 ! parathyroid gland development GO:0060017 8 5 1,000 2,26E-04 7,758E-03 ! epithelial cell proliferation GO:0050673 6 5 1,000 2,26E-04 7,644E-03 ! embryonic hemopoiesis GO:0035162 10 5 1,000 2,26E-04 7,534E-03 ! positive regulation of chemokine production GO:0032722 7 5 1,000 2,26E-04 7,426E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 2,26E-04 7,321E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 2,26E-04 7,22E-03 ! peptidyl-tyrosine modification GO:0018212 37 25 2,000 2,28E-04 7,185E-03 ! respiratory system development GO:0060541 100 64 3,000 2,53E-04 7,865E-03 ! negative regulation of protein modification process GO:0031400 50 26 2,000 2,569E-04 7,878E-03 ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 3,214E-04 9,728E-03 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 3,214E-04 9,601E-03 ! positive regulation of catabolic process GO:0009896 40 28 2,000 3,214E-04 9,478E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 3,38E-04 9,839E-03 ! mRNA stabilization GO:0048255 15 6 1,000 3,38E-04 9,716E-03 GO:0043489|RNA stabilization, ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 1,000 3,38E-04 9,596E-03 ! male sex determination GO:0030238 9 6 1,000 3,38E-04 9,479E-03 ! gas homeostasis GO:0033483 11 6 1,000 3,38E-04 9,365E-03 ! response to hypoxia GO:0001666 132 72 3,000 3,979E-04 0,0108962 ! leukocyte chemotaxis GO:0030595 43 31 2,000 4,365E-04 0,01181086 GO:0060326|cell chemotaxis, ! response to oxygen levels GO:0070482 137 74 3,000 4,418E-04 0,01181683 ! T-helper 1 type immune response GO:0042088 11 7 1,000 4,717E-04 0,01246898 ! hemoglobin metabolic process GO:0020027 10 7 1,000 4,717E-04 0,01232729 ! protein heterooligomerization GO:0051291 10 7 1,000 4,717E-04 0,01218878 ! positive regulation of monooxygenase activity GO:0032770 11 7 1,000 4,717E-04 0,01205335 ! carbohydrate homeostasis GO:0033500 39 33 2,000 5,261E-04 0,01329829 GO:0042593|glucose homeostasis, ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 5,751E-04 0,01437683 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 6,269E-04 0,01550415 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 6,269E-04 0,01533922 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 6,269E-04 0,01517775 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 6,269E-04 0,01501965 ! regulation of vascular permeability GO:0043114 12 8 1,000 6,269E-04 0,01486481 ! regulation of Notch signaling pathway GO:0008593 18 8 1,000 6,269E-04 0,01471313 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 6,269E-04 0,01456451 ! regulation of embryonic development GO:0045995 16 8 1,000 6,269E-04 0,01441886 ! tissue remodeling GO:0048771 62 36 2,000 6,814E-04 0,01551781 ! regulation of developmental growth GO:0048638 13 9 1,000 8,035E-04 0,01811832 ! lung alveolus development GO:0048286 17 9 1,000 8,035E-04 0,01794241 ! regulation of hormone metabolic process GO:0032350 15 9 1,000 8,035E-04 0,01776989 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 1,000 8,035E-04 0,01760065 ! thymus development GO:0048538 15 9 1,000 8,035E-04 0,01743461 ! embryonic placenta development GO:0001892 12 9 1,000 8,035E-04 0,01727167 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,001E-03 0,02132295 ! blood vessel remodeling GO:0001974 21 10 1,000 1,001E-03 0,02112733 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,001E-03 0,02093526 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 1,001E-03 0,02074665 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 1,000 1,001E-03 0,02056141 ! regulation of bone resorption GO:0045124 24 10 1,000 1,001E-03 0,02037946 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 1,001E-03 0,02020069 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 1,046E-03 0,02092703 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 1,15E-03 0,02279472 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 1,15E-03 0,02259989 ! leukocyte migration GO:0050900 60 43 2,000 1,15E-03 0,02240837 ! regulation of response to external stimulus GO:0032101 139 96 3,000 1,178E-03 0,02276032 ! ER-associated protein catabolic process GO:0030433 14 11 1,000 1,22E-03 0,0233821 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! virus-host interaction GO:0019048 17 11 1,000 1,22E-03 0,02318886 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 1,22E-03 0,02299878 ! plasma membrane organization GO:0007009 18 11 1,000 1,22E-03 0,0228118 ! focal adhesion formation GO:0048041 24 11 1,000 1,22E-03 0,02262783 ! regulation of vascular endothelial growth factor production GO:0010574 19 11 1,000 1,22E-03 0,02244681 ! regulation of leukocyte migration GO:0002685 24 11 1,000 1,22E-03 0,02226866 ! regulation of cell projection organization GO:0031344 83 44 2,000 1,23E-03 0,02226675 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 1,23E-03 0,02209279 ! regulation of inflammatory response GO:0050727 60 44 2,000 1,23E-03 0,02192153 ! positive regulation of defense response GO:0031349 59 45 2,000 1,313E-03 0,02322631 ! auditory receptor cell differentiation GO:0042491 25 12 1,000 1,459E-03 0,02562233 ! heart looping GO:0001947 15 12 1,000 1,459E-03 0,02542822 ! Golgi organization GO:0007030 18 12 1,000 1,459E-03 0,02523703 ! histone acetylation GO:0016573 23 12 1,000 1,459E-03 0,02504869 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,459E-03 0,02486315 ! regulation of mRNA stability GO:0043488 27 12 1,000 1,459E-03 0,02468033 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 1,459E-03 0,02450018 ! endocrine system development GO:0035270 83 47 2,000 1,49E-03 0,02483017 ! regulation of muscle contraction GO:0006937 69 48 2,000 1,584E-03 0,02620435 ! heart morphogenesis GO:0003007 65 48 2,000 1,584E-03 0,02601717 ! regulation of DNA replication GO:0006275 75 48 2,000 1,584E-03 0,02583265 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,719E-03 0,02784817 ! regulation of chemokine production GO:0032642 17 13 1,000 1,719E-03 0,02765343 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 1,719E-03 0,02746139 ! regulation of RNA stability GO:0043487 28 13 1,000 1,719E-03 0,027272 ! membrane fusion GO:0006944 80 50 2,000 1,782E-03 0,02807683 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 1,887E-03 0,02952664 ! establishment of organelle localization GO:0051656 85 52 2,000 1,996E-03 0,03101551 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 2E-03 0,03086672 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 2E-03 0,03066094 ! pituitary gland development GO:0021983 23 14 1,000 2E-03 0,03045789 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 2E-03 0,03025751 ! muscle maintenance GO:0046716 19 14 1,000 2E-03 0,03005974 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 2E-03 0,02986455 ! regulation of protein complex assembly GO:0043254 81 54 2,000 2,225E-03 0,03300981 ! lipid phosphorylation GO:0046834 23 15 1,000 2,3E-03 0,03391138 ! positive regulation of oxidoreductase activity GO:0051353 21 15 1,000 2,3E-03 0,03369538 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 2,3E-03 0,03348212 ! regulation of lipid metabolic process GO:0019216 84 56 2,000 2,469E-03 0,03571536 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 2,469E-03 0,03549214 ! protein amino acid acetylation GO:0006473 28 16 1,000 2,62E-03 0,03743536 ! diencephalon development GO:0021536 25 16 1,000 2,62E-03 0,03720428 ! neural crest cell migration GO:0001755 24 16 1,000 2,62E-03 0,03697603 ! inner ear receptor cell differentiation GO:0060113 30 16 1,000 2,62E-03 0,03675056 ! myeloid cell differentiation GO:0030099 85 59 2,000 2,866E-03 0,03994752 ! cell-substrate junction assembly GO:0007044 39 17 1,000 2,961E-03 0,04102077 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 2,961E-03 0,04077514 ! actin filament bundle formation GO:0051017 26 17 1,000 2,961E-03 0,04053243 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 2,961E-03 0,04029259 ! regulation of heart contraction GO:0008016 91 60 2,000 3,006E-03 0,04067294 ! regulation of homeostatic process GO:0032844 105 60 2,000 3,006E-03 0,04043508 ! cell-matrix adhesion GO:0007160 114 61 2,000 3,151E-03 0,04213398 ! organelle localization GO:0051640 96 62 2,000 3,3E-03 0,04386917 ! positive regulation of DNA replication GO:0045740 29 18 1,000 3,32E-03 0,04388964 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 3,32E-03 0,04363884 ! mechanoreceptor differentiation GO:0042490 32 18 1,000 3,32E-03 0,04339089 ! pigmentation during development GO:0048066 31 18 1,000 3,32E-03 0,04314575 ! somitogenesis GO:0001756 24 18 1,000 3,32E-03 0,04290336 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 3,32E-03 0,04266367 ! regulation of transcription factor activity GO:0051090 97 63 2,000 3,453E-03 0,04411919 GO:0090046|regulation of transcription regulator activity, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 2,000 3,453E-03 0,04387544 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 2,000 3,61E-03 0,04562305 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 3,699E-03 0,04649564 ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 3,699E-03 0,04624294 ! sex determination GO:0007530 29 19 1,000 3,699E-03 0,04599298 ! plasma membrane fusion GO:0045026 23 19 1,000 3,699E-03 0,04574571 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 3,699E-03 0,04550108 ! negative regulation of angiogenesis GO:0016525 36 19 1,000 3,699E-03 0,04525905 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 3,699E-03 0,04501958 ! cell-substrate adhesion GO:0031589 121 66 2,000 3,938E-03 0,04766934 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 4,098E-03 0,0493441 ! regulation of ARF GTPase activity GO:0032312 31 20 1,000 4,098E-03 0,0490871 ! positive regulation of B cell activation GO:0050871 31 20 1,000 4,098E-03 0,04883276 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 4,515E-03 0,05352798 ! protein amino acid acylation GO:0043543 37 21 1,000 4,515E-03 0,05325348 ! platelet activation GO:0030168 28 21 1,000 4,515E-03 0,05298178 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 4,515E-03 0,05271283 ! positive regulation of phosphorylation GO:0042327 102 70 2,000 4,646E-03 0,05397267 ! regulation of catabolic process GO:0009894 106 70 2,000 4,646E-03 0,05370145 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 4,951E-03 0,05693693 ! protein tetramerization GO:0051262 39 22 1,000 4,951E-03 0,05665366 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 2,000 5,028E-03 0,05724482 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of transport GO:0051051 116 73 2,000 5,225E-03 0,0592004 ! neuron fate commitment GO:0048663 32 23 1,000 5,406E-03 0,06094691 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 5,406E-03 0,06064961 ! interaction with host GO:0051701 37 23 1,000 5,406E-03 0,06035519 ! cellular response to oxidative stress GO:0034599 33 23 1,000 5,406E-03 0,06006362 ! cell fate determination GO:0001709 45 23 1,000 5,406E-03 0,05977485 ! liver development GO:0001889 40 23 1,000 5,406E-03 0,05948885 ! negative regulation of growth GO:0045926 123 75 2,000 5,634E-03 0,06170509 ! response to nutrient GO:0007584 104 75 2,000 5,634E-03 0,06141265 ! neural crest cell development GO:0014032 39 24 1,000 5,879E-03 0,06377997 GO:0014033|neural crest cell differentiation, ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 5,879E-03 0,06348053 ! regulation of DNA binding GO:0051101 119 77 2,000 6,062E-03 0,06514708 ! gland development GO:0048732 148 77 2,000 6,062E-03 0,06484407 ! positive regulation of protein modification process GO:0031401 107 78 2,000 6,282E-03 0,06689569 ! iron ion homeostasis GO:0055072 39 25 1,000 6,37E-03 0,06751851 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 6,88E-03 0,07258367 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 6,88E-03 0,07225224 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 7,407E-03 0,07743685 GO:0043433|negative regulation of transcription factor activity, ! regulation of defense response GO:0031347 117 84 2,000 7,708E-03 0,08022272 ! cell junction assembly GO:0034329 56 28 1,000 7,952E-03 0,08238607 ! placenta development GO:0001890 37 28 1,000 7,952E-03 0,08201663 ! regulation of B cell activation GO:0050864 42 28 1,000 7,952E-03 0,08165048 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 7,963E-03 0,08139996 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 7,963E-03 0,08103978 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 7,963E-03 0,08068278 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 8,223E-03 0,08294773 ! interphase GO:0051325 159 88 2,000 8,757E-03 0,08794945 ! collagen metabolic process GO:0032963 40 30 1,000 9,095E-03 0,0909455 ! leukocyte differentiation GO:0002521 143 90 2,000 9,311E-03 0,09270395 ! response to virus GO:0009615 122 91 2,000 9,595E-03 0,09512503 ! segmentation GO:0035282 41 31 1,000 9,692E-03 0,09566873 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 9,692E-03 0,09525989 ! regulation of ARF protein signal transduction GO:0032012 51 32 1,000 0,01030577 0,10086498 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,01030577 0,10043759 ! regulation of binding GO:0051098 151 95 2,000 0,01078385 0,10465344 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,01093671 0,10569093 ! cell junction organization GO:0034330 63 33 1,000 0,01093671 0,10524871 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 1,000 0,01093671 0,10481017 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,01093671 0,10437527 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 0,01109373 0,10543631 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,01158432 0,10964579 ! embryonic organ development GO:0048568 45 34 1,000 0,01158432 0,10919642 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,01205414 0,11316132 ! Notch signaling pathway GO:0007219 56 35 1,000 0,01224841 0,11451763 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,01224841 0,11405399 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01292882 0,11990435 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 0,01292882 0,11942281 ! amino acid activation GO:0043038 52 37 1,000 0,01362538 0,12535348 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! pigmentation GO:0043473 74 38 1,000 0,01433792 0,13138336 ! mesenchymal cell development GO:0014031 64 38 1,000 0,01433792 0,13086199 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 0,01506629 0,13696623 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 0,01506629 0,136427 ! JNK cascade GO:0007254 54 39 1,000 0,01506629 0,13589199 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 0,0158103 0,14204568 ! inner ear development GO:0048839 57 40 1,000 0,0158103 0,14149297 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,0158103 0,14094455 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,0158103 0,14040036 ! epithelial cell differentiation GO:0030855 55 41 1,000 0,01656981 0,14657907 ! glucose transport GO:0015758 52 41 1,000 0,01656981 0,14601746 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,01656981 0,14546014 ! receptor-mediated endocytosis GO:0006898 76 42 1,000 0,01734464 0,15168317 ! hexose transport GO:0008645 54 42 1,000 0,01734464 0,15110861 GO:0015749|monosaccharide transport, ! regulation of cell shape GO:0008360 78 42 1,000 0,01734464 0,15053839 ! positive regulation of binding GO:0051099 59 43 1,000 0,01813464 0,15680328 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,01893965 0,16315051 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,01893965 0,16254174 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,0197595 0,1689474 ! cell maturation GO:0048469 60 45 1,000 0,0197595 0,16832167 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,0197595 0,16770056 ! histone modification GO:0016570 68 46 1,000 0,02059404 0,17414081 ! response to UV GO:0009411 75 46 1,000 0,02059404 0,17350294 ! covalent chromatin modification GO:0016569 75 47 1,000 0,02144312 0,179997 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 0,02144312 0,17934247 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of cytokine production GO:0001819 73 48 1,000 0,02230658 0,18588814 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02379764 0,19759773 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02379764 0,19688695 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02379764 0,19618126 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02379764 0,19548061 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02379764 0,19478495 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02379764 0,19409422 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02379764 0,19340838 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02379764 0,19272736 ! sleep GO:0030431 11 5 0,000 0,02379764 0,19205113 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02379764 0,19137962 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02379764 0,19071279 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02379764 0,19005059 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02379764 0,18939298 ! tongue development GO:0043586 6 5 0,000 0,02379764 0,1887399 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02379764 0,18809131 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02379764 0,18744716 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02379764 0,18680741 ! cobalt ion transport GO:0006824 9 5 0,000 0,02379764 0,18617201 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02379764 0,18554092 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02379764 0,18491409 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02379764 0,18429149 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02379764 0,18367306 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02379764 0,18305877 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02379764 0,18244857 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02379764 0,18184243 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02379764 0,1812403 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02379764 0,18064215 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02379764 0,18004793 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02379764 0,17945761 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02379764 0,17887115 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,02379764 0,17828851 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02379764 0,17770965 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02379764 0,17713453 ! malate metabolic process GO:0006108 7 5 0,000 0,02379764 0,17656313 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02379764 0,17599541 ! behavioral response to pain GO:0048266 7 5 0,000 0,02379764 0,17543132 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02379764 0,17487083 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02379764 0,17431392 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02379764 0,17376054 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02379764 0,17321067 ! mating behavior GO:0007617 6 5 0,000 0,02379764 0,17266426 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02379764 0,17212129 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02379764 0,17158173 ! rhythmic behavior GO:0007622 12 5 0,000 0,02379764 0,17104553 ! copulation GO:0007620 7 5 0,000 0,02379764 0,17051268 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02379764 0,16998314 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02379764 0,16945688 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02379764 0,16893386 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02379764 0,16841407 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02379764 0,16789746 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02379764 0,16738401 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02379764 0,16687369 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02379764 0,16636648 ! response to protozoan GO:0001562 9 5 0,000 0,02379764 0,16586234 ! lymph vessel development GO:0001945 7 5 0,000 0,02379764 0,16536124 ! endochondral ossification GO:0001958 12 5 0,000 0,02379764 0,16486317 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02379764 0,16436808 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02379764 0,16387596 ! anagen GO:0042640 6 5 0,000 0,02379764 0,16338678 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02379764 0,16290051 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02379764 0,16241713 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02379764 0,1619366 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02379764 0,16145891 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02379764 0,16098403 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02379764 0,16051194 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02379764 0,16004261 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02379764 0,15957601 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02379764 0,15911213 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02379764 0,15865093 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,02379764 0,1581924 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02379764 0,15773652 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02379764 0,15728325 ! ovulation GO:0030728 6 5 0,000 0,02379764 0,15683258 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02379764 0,15638449 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02379764 0,15593895 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,02379764 0,15549594 ! response to pH GO:0009268 9 5 0,000 0,02379764 0,15505544 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02379764 0,15461743 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02379764 0,15418189 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02379764 0,1537488 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02379764 0,15331813 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02379764 0,15288986 ! polyol catabolic process GO:0046174 7 5 0,000 0,02379764 0,15246399 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02379764 0,15204048 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02379764 0,15161931 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02379764 0,15120047 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02379764 0,15078394 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02379764 0,1503697 ! urea metabolic process GO:0019627 6 5 0,000 0,02379764 0,14995773 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02379764 0,14954801 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02379764 0,14914052 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02379764 0,14873525 ! neutrophil activation GO:0042119 5 5 0,000 0,02379764 0,14833217 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02379764 0,14793127 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02379764 0,14753254 ! response to food GO:0032094 5 5 0,000 0,02379764 0,14713594 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02379764 0,14674148 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02379764 0,14634912 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02379764 0,14595886 ! forebrain neuron development GO:0021884 7 5 0,000 0,02379764 0,14557067 ! melanosome organization GO:0032438 7 5 0,000 0,02379764 0,14518454 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02379764 0,14480045 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02379764 0,14441839 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02379764 0,14403835 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02379764 0,14366029 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02379764 0,14328422 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02379764 0,14291011 ! nucleoside transport GO:0015858 6 5 0,000 0,02379764 0,14253795 ! nucleoside salvage GO:0043174 7 5 0,000 0,02379764 0,14216772 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02379764 0,14179941 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02379764 0,141433 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02379764 0,14106848 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02379764 0,14070584 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02379764 0,14034505 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02379764 0,13998612 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02379764 0,13962901 ! depyrimidination GO:0045008 8 5 0,000 0,02379764 0,13927372 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02379764 0,13892023 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02379764 0,13856853 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02379764 0,13821861 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02379764 0,13787046 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02379764 0,13752405 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02379764 0,13717938 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02379764 0,13683643 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02379764 0,13649519 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02379764 0,13615565 ! monocyte differentiation GO:0030224 8 5 0,000 0,02379764 0,13581779 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02379764 0,13548161 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02379764 0,13514709 ! centrosome duplication GO:0051298 5 5 0,000 0,02379764 0,13481421 ! response to UV-C GO:0010225 6 5 0,000 0,02379764 0,13448298 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02379764 0,13415336 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02379764 0,13382536 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02379764 0,13349895 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02379764 0,13317414 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02379764 0,1328509 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02379764 0,13252923 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02379764 0,13220911 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02379764 0,13189053 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02379764 0,13157349 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02379764 0,13125796 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02379764 0,13094395 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02379764 0,13063143 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02379764 0,13032041 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02379764 0,13001086 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02379764 0,12970278 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02379764 0,12939615 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02379764 0,12909097 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02379764 0,12878723 ! neural tube patterning GO:0021532 6 5 0,000 0,02379764 0,12848491 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02379764 0,12818401 ! histone demethylation GO:0016577 9 5 0,000 0,02379764 0,12788451 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02379764 0,12758641 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02379764 0,1272897 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02379764 0,12699436 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02379764 0,1267004 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02379764 0,12640779 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02379764 0,12611652 ! transcription termination GO:0006353 8 5 0,000 0,02379764 0,1258266 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02379764 0,12553801 ! plasminogen activation GO:0031639 5 5 0,000 0,02379764 0,12525073 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02379764 0,12496477 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02379764 0,12468012 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02379764 0,12439675 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02379764 0,12411467 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02379764 0,12383387 ! apical protein localization GO:0045176 6 5 0,000 0,02379764 0,12355434 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02379764 0,12327606 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02379764 0,12299904 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02379764 0,12272325 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02379764 0,12244871 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02379764 0,12217538 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02379764 0,12190328 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02379764 0,12163238 ! glial cell migration GO:0008347 10 5 0,000 0,02379764 0,12136269 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02379764 0,12109418 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02379764 0,12082687 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02379764 0,12056073 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02379764 0,12029576 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02379764 0,12003195 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02379764 0,1197693 ! neural plate development GO:0001840 6 5 0,000 0,02379764 0,1195078 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02379764 0,11924743 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02379764 0,1189882 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02379764 0,11873009 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02379764 0,1184731 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02379764 0,11821722 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02379764 0,11796244 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02379764 0,11770876 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02379764 0,11745616 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02379764 0,11720465 ! spindle assembly GO:0051225 5 5 0,000 0,02379764 0,11695421 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02379764 0,11670484 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02379764 0,11645653 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02379764 0,11620928 ! organ regeneration GO:0031100 7 5 0,000 0,02379764 0,11596307 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02379764 0,11571791 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02379764 0,11547378 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02379764 0,11523068 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02379764 0,11498859 GO:0055081|anion homeostasis, ! ear development GO:0043583 72 50 1,000 0,024076 0,11608975 ! lipid modification GO:0030258 73 50 1,000 0,024076 0,11584688 ! positive regulation of growth GO:0045927 67 50 1,000 0,024076 0,11560503 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,02498167 0,11970385 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,02683416 0,12831304 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,02778068 0,13256343 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,02778068 0,13228897 ! tRNA transcription GO:0009304 11 6 0,000 0,02848958 0,13538436 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02848958 0,13510521 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02848958 0,13482722 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02848958 0,13455037 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02848958 0,13427465 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02848958 0,13400006 ! regulation of helicase activity GO:0051095 11 6 0,000 0,02848958 0,13372659 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02848958 0,13345423 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02848958 0,13318298 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02848958 0,13291284 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02848958 0,13264378 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02848958 0,13237581 ! prostate gland development GO:0030850 9 6 0,000 0,02848958 0,13210893 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02848958 0,13184312 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02848958 0,13157837 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02848958 0,13131469 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02848958 0,13105206 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02848958 0,13079048 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02848958 0,13052994 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02848958 0,13027043 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02848958 0,13001196 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02848958 0,12975451 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02848958 0,12949808 ! neuron adhesion GO:0007158 9 6 0,000 0,02848958 0,12924266 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02848958 0,12898824 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02848958 0,12873483 ! signal peptide processing GO:0006465 8 6 0,000 0,02848958 0,12848241 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02848958 0,12823098 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02848958 0,12798052 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02848958 0,12773105 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02848958 0,12748255 ! opsonization GO:0008228 8 6 0,000 0,02848958 0,12723501 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02848958 0,12698843 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02848958 0,1267428 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02848958 0,12649812 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02848958 0,12625439 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02848958 0,12601159 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02848958 0,12576973 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02848958 0,12552879 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02848958 0,12528877 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02848958 0,12504967 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02848958 0,12481148 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02848958 0,1245742 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02848958 0,12433781 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02848958 0,12410233 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02848958 0,12386773 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02848958 0,12363402 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02848958 0,12340118 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02848958 0,12316923 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02848958 0,12293814 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02848958 0,12270792 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02848958 0,12247856 ! thymic T cell selection GO:0045061 12 6 0,000 0,02848958 0,12225005 ! protein lipoylation GO:0009249 10 6 0,000 0,02848958 0,1220224 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02848958 0,12179559 ! pigment granule organization GO:0048753 11 6 0,000 0,02848958 0,12156963 ! drug transport GO:0015893 6 6 0,000 0,02848958 0,1213445 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02848958 0,1211202 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02848958 0,12089673 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02848958 0,12067409 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02848958 0,12045226 ! histidine metabolic process GO:0006547 6 6 0,000 0,02848958 0,12023124 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02848958 0,12001104 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02848958 0,11979164 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02848958 0,11957304 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02848958 0,11935524 ! adenohypophysis development GO:0021984 10 6 0,000 0,02848958 0,11913823 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02848958 0,11892201 ! hyperosmotic response GO:0006972 8 6 0,000 0,02848958 0,11870657 ! microtubule nucleation GO:0007020 10 6 0,000 0,02848958 0,11849191 ! ER overload response GO:0006983 7 6 0,000 0,02848958 0,11827803 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02848958 0,11806492 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02848958 0,11785257 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02848958 0,11764098 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02848958 0,11743016 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02848958 0,11722009 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02848958 0,11701076 ! response to dietary excess GO:0002021 7 6 0,000 0,02848958 0,11680219 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02848958 0,11659436 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02848958 0,11638726 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02848958 0,1161809 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02848958 0,11597527 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02848958 0,11577037 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02848958 0,11556619 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02848958 0,11536273 ! neuron apoptosis GO:0051402 8 6 0,000 0,02848958 0,11515998 ! organic alcohol transport GO:0015850 9 6 0,000 0,02848958 0,11495794 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02848958 0,11475662 ! carnitine transport GO:0015879 8 6 0,000 0,02848958 0,11455599 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02848958 0,11435607 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02848958 0,11415684 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02848958 0,11395831 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02848958 0,11376047 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02848958 0,11356331 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02848958 0,11336683 ! parturition GO:0007567 12 6 0,000 0,02848958 0,11317103 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02848958 0,11297591 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02848958 0,11278146 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02848958 0,11258768 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02848958 0,11239456 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02848958 0,1122021 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02848958 0,1120103 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02848958 0,11181916 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02848958 0,11162867 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02848958 0,11143882 ! astrocyte development GO:0014002 14 6 0,000 0,02848958 0,11124962 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02848958 0,11106106 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02848958 0,11087314 ! interaction with symbiont GO:0051702 8 6 0,000 0,02848958 0,11068586 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02848958 0,1104992 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02848958 0,11031318 ! eating behavior GO:0042755 6 6 0,000 0,02848958 0,11012778 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02848958 0,109943 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02848958 0,10975884 ! response to copper ion GO:0046688 9 6 0,000 0,02848958 0,1095753 ! DNA topological change GO:0006265 8 6 0,000 0,02848958 0,10939237 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02848958 0,10921005 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02848958 0,10902833 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02848958 0,10884722 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02848958 0,10866671 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02848958 0,1084868 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02848958 0,10830748 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02848958 0,10812876 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02848958 0,10795062 ! hair follicle maturation GO:0048820 7 6 0,000 0,02848958 0,10777307 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02848958 0,10759611 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02848958 0,10741972 ! Schwann cell development GO:0014044 14 6 0,000 0,02848958 0,10724391 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02848958 0,10706867 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02848958 0,10689401 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02848958 0,10671992 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02848958 0,10654639 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02848958 0,10637342 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02848958 0,10620102 ! histone ubiquitination GO:0016574 7 6 0,000 0,02848958 0,10602917 ! regulation of meiosis GO:0040020 10 6 0,000 0,02848958 0,10585788 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02848958 0,10568714 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02848958 0,10551695 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02848958 0,10534731 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02848958 0,10517822 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02848958 0,10500966 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02848958 0,10484165 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02848958 0,10467417 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02848958 0,10450722 ! receptor internalization GO:0031623 9 6 0,000 0,02848958 0,10434081 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02848958 0,10417493 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02848958 0,10400957 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02848958 0,10384474 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02848958 0,10368042 ! protein deubiquitination GO:0016579 8 6 0,000 0,02848958 0,10351663 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02848958 0,10335336 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02848958 0,1031906 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02848958 0,10302835 ! axonal fasciculation GO:0007413 9 6 0,000 0,02848958 0,10286661 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02848958 0,10270537 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02848958 0,10254465 ! midbrain development GO:0030901 6 6 0,000 0,02848958 0,10238442 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02848958 0,10222469 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02848958 0,10206546 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02848958 0,10190673 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02848958 0,10174849 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02848958 0,10159074 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02848958 0,10143348 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02848958 0,10127671 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02848958 0,10112041 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02848958 0,1009646 ! adult feeding behavior GO:0008343 6 6 0,000 0,02848958 0,10080927 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02848958 0,10065442 ! blastocyst growth GO:0001832 15 6 0,000 0,02848958 0,10050004 ! pigment granule transport GO:0051904 12 6 0,000 0,02848958 0,10034614 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02848958 0,1001927 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02848958 0,10003974 ! catecholamine transport GO:0051937 7 6 0,000 0,02848958 0,09988724 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02848958 0,0997352 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02848958 0,09958363 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02848958 0,09943252 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02848958 0,09928186 ! protein prenylation GO:0018342 10 6 0,000 0,02848958 0,09913166 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02848958 0,09898192 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02848958 0,09883262 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02848958 0,09868378 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02848958 0,09853538 ! mesoderm development GO:0007498 76 55 1,000 0,02874053 0,09925408 ! carbohydrate transport GO:0008643 74 57 1,000 0,0306996 0,10586067 ! developmental maturation GO:0021700 75 57 1,000 0,0306996 0,1057022 ! viral reproductive process GO:0022415 87 58 1,000 0,03169853 0,1089785 ! activation of MAPK activity GO:0000187 84 59 1,000 0,0327102 0,11228876 ! actin filament organization GO:0007015 95 59 1,000 0,0327102 0,11212141 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,03315923 0,11349142 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,03315923 0,11332278 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03315923 0,11315465 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03315923 0,11298701 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,03315923 0,11281987 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03315923 0,11265322 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03315923 0,11248707 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,03315923 0,1123214 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03315923 0,11215622 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,03315923 0,11199153 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03315923 0,11182732 ! reproductive behavior GO:0019098 12 7 0,000 0,03315923 0,11166359 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03315923 0,11150034 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,03315923 0,11133757 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,03315923 0,11117527 ! oligopeptide transport GO:0006857 11 7 0,000 0,03315923 0,11101344 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03315923 0,11085208 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03315923 0,11069119 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,03315923 0,11053077 ! RNA methylation GO:0001510 11 7 0,000 0,03315923 0,11037081 ! pericardium development GO:0060039 8 7 0,000 0,03315923 0,11021132 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03315923 0,11005228 ! fibril organization GO:0043206 13 7 0,000 0,03315923 0,10989371 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,03315923 0,10973559 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03315923 0,10957792 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,03315923 0,10942071 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03315923 0,10926394 ! lipoprotein transport GO:0042953 9 7 0,000 0,03315923 0,10910763 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03315923 0,10895176 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03315923 0,10879634 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03315923 0,10864136 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03315923 0,10848682 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03315923 0,10833272 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03315923 0,10817905 ! chemosensory behavior GO:0007635 9 7 0,000 0,03315923 0,10802583 ! microtubule bundle formation GO:0001578 8 7 0,000 0,03315923 0,10787303 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03315923 0,10772067 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03315923 0,10756873 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03315923 0,10741723 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03315923 0,10726615 ! reflex GO:0060004 12 7 0,000 0,03315923 0,1071155 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03315923 0,10696526 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03315923 0,10681545 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03315923 0,10666606 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03315923 0,10651708 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,03315923 0,10636853 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03315923 0,10622038 ! spinal cord patterning GO:0021511 7 7 0,000 0,03315923 0,10607265 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,03315923 0,10592532 ! adrenal gland development GO:0030325 17 7 0,000 0,03315923 0,10577841 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03315923 0,1056319 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03315923 0,1054858 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03315923 0,1053401 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03315923 0,1051948 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03315923 0,10504991 ! endosome organization GO:0007032 10 7 0,000 0,03315923 0,10490541 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03315923 0,10476131 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03315923 0,1046176 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03315923 0,10447429 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03315923 0,10433137 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03315923 0,10418884 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,03315923 0,1040467 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03315923 0,10390495 ! galactose metabolic process GO:0006012 10 7 0,000 0,03315923 0,10376358 ! vesicle fusion GO:0006906 15 7 0,000 0,03315923 0,1036226 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03315923 0,103482 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,03315923 0,10334178 ! organ growth GO:0035265 11 7 0,000 0,03315923 0,10320194 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03315923 0,10306248 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,03315923 0,10292339 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03315923 0,10278468 ! retinol metabolic process GO:0042572 9 7 0,000 0,03315923 0,10264634 ! behavioral fear response GO:0001662 13 7 0,000 0,03315923 0,10250838 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,03315923 0,10237078 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03315923 0,10223356 ! rRNA modification GO:0000154 12 7 0,000 0,03315923 0,1020967 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03315923 0,1019602 ! response to UV-B GO:0010224 11 7 0,000 0,03315923 0,10182408 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,03315923 0,10168831 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03315923 0,10155291 ! intermediate filament organization GO:0045109 11 7 0,000 0,03315923 0,10141786 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,03315923 0,10128318 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03315923 0,10114885 ! fibrinolysis GO:0042730 9 7 0,000 0,03315923 0,10101488 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03315923 0,10088126 ! B cell lineage commitment GO:0002326 17 7 0,000 0,03315923 0,100748 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03315923 0,10061508 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03315923 0,10048252 ! response to tropane GO:0014073 13 7 0,000 0,03315923 0,10035031 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,03315923 0,10021844 ! melanosome localization GO:0032400 10 7 0,000 0,03315923 0,10008692 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03315923 0,09995574 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03315923 0,09982491 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03315923 0,09969442 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03315923 0,09956427 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03315923 0,09943446 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03315923 0,09930499 ! mast cell activation GO:0045576 9 7 0,000 0,03315923 0,09917586 ! multicellular organismal aging GO:0010259 11 7 0,000 0,03315923 0,09904706 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,03315923 0,09891859 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03315923 0,09879046 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03315923 0,09866266 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,03315923 0,09853518 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03315923 0,09840804 ! T cell lineage commitment GO:0002360 12 7 0,000 0,03315923 0,09828123 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,03315923 0,09815474 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03315923 0,09802858 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03315923 0,09790274 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03315923 0,09777722 ! response to tumor cell GO:0002347 12 7 0,000 0,03315923 0,09765203 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03315923 0,09752715 ! neuroblast proliferation GO:0007405 13 7 0,000 0,03315923 0,0974026 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03315923 0,09727836 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,03315923 0,09715444 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,03315923 0,09703083 ! diuresis GO:0030146 12 7 0,000 0,03315923 0,09690754 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03315923 0,09678456 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03315923 0,09666189 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03315923 0,09653954 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03315923 0,09641749 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03315923 0,09629575 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03315923 0,09617432 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03315923 0,09605319 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03315923 0,09593237 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03315923 0,09581185 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03315923 0,09569163 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03315923 0,09557172 ! lymph node development GO:0048535 9 7 0,000 0,03315923 0,09545211 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,03315923 0,09533279 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,03315923 0,09521377 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03315923 0,09509505 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,03315923 0,09497663 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03315923 0,0948585 ! ATP catabolic process GO:0006200 10 7 0,000 0,03315923 0,09474066 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03315923 0,09462312 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,03315923 0,09450586 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03315923 0,0943889 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03315923 0,09427223 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03315923 0,09415584 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03315923 0,09403974 ! muscle adaptation GO:0043500 12 7 0,000 0,03315923 0,09392393 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03315923 0,0938084 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03315923 0,09369316 ! retina homeostasis GO:0001895 9 7 0,000 0,03315923 0,0935782 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03315923 0,09346352 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,03315923 0,09334912 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,03315923 0,093235 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,03315923 0,09312116 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03315923 0,0930076 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03315923 0,09289432 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03315923 0,09278131 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,03373448 0,09427618 ! negative regulation of cell growth GO:0030308 106 62 1,000 0,03582026 0,09998373 ! viral reproduction GO:0016032 92 63 1,000 0,03688149 0,10282111 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03780671 0,10527291 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03780671 0,10514562 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,03780671 0,10501863 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,03780671 0,10489195 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03780671 0,10476557 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03780671 0,1046395 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03780671 0,10451373 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03780671 0,10438827 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03780671 0,1042631 ! phosphate transport GO:0006817 10 8 0,000 0,03780671 0,10413823 ! N-glycan processing GO:0006491 12 8 0,000 0,03780671 0,10401367 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03780671 0,1038894 ! UTP metabolic process GO:0046051 8 8 0,000 0,03780671 0,10376542 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03780671 0,10364175 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03780671 0,10351836 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03780671 0,10339527 ! succinate metabolic process GO:0006105 14 8 0,000 0,03780671 0,10327248 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,03780671 0,10314997 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03780671 0,10302775 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03780671 0,10290583 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,03780671 0,10278419 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,03780671 0,10266284 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,03780671 0,10254177 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03780671 0,102421 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03780671 0,1023005 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03780671 0,10218029 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03780671 0,10206036 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03780671 0,10194071 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,03780671 0,10182134 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03780671 0,10170225 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03780671 0,10158344 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03780671 0,10146491 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03780671 0,10134665 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,03780671 0,10122867 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03780671 0,10111096 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03780671 0,10099353 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03780671 0,10087636 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03780671 0,10075947 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,03780671 0,10064285 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03780671 0,1005265 ! melanin metabolic process GO:0006582 12 8 0,000 0,03780671 0,10041042 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03780671 0,10029461 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03780671 0,10017906 ! macrophage activation GO:0042116 12 8 0,000 0,03780671 0,10006378 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03780671 0,09994876 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03780671 0,09983401 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03780671 0,09971952 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03780671 0,0996053 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,03780671 0,09949133 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03780671 0,09937763 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03780671 0,09926418 ! ruffle organization GO:0031529 11 8 0,000 0,03780671 0,099151 ! osteoblast development GO:0002076 13 8 0,000 0,03780671 0,09903807 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,03780671 0,0989254 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03780671 0,09881298 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03780671 0,09870082 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03780671 0,09858892 GO:0007351|tripartite regional subdivision, ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03780671 0,09847727 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03780671 0,09836587 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03780671 0,09825472 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03780671 0,09814382 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,03780671 0,09803317 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,03780671 0,09792278 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03780671 0,09781263 ! segment specification GO:0007379 10 8 0,000 0,03780671 0,09770272 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,03780671 0,09759307 ! cellular extravasation GO:0045123 11 8 0,000 0,03780671 0,09748366 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03780671 0,0973745 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,03780671 0,09726558 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03780671 0,0971569 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,03780671 0,09704847 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03780671 0,09694027 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03780671 0,09683232 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03780671 0,09672461 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03780671 0,09661714 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03780671 0,09650991 ! nucleosome disassembly GO:0006337 12 8 0,000 0,03780671 0,09640291 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03780671 0,09629615 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03780671 0,09618963 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03780671 0,09608334 ! icosanoid secretion GO:0032309 12 8 0,000 0,03780671 0,09597729 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,03780671 0,09587147 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03780671 0,09576589 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03780671 0,09566053 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03780671 0,09555541 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03780671 0,09545052 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03780671 0,09534586 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03780671 0,09524143 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,03780671 0,09513723 ! sterol catabolic process GO:0016127 9 8 0,000 0,03780671 0,09503325 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03780671 0,0949295 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03780671 0,09482598 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03780671 0,09472269 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03780671 0,09461961 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03780671 0,09451677 ! prophase GO:0051324 11 8 0,000 0,03780671 0,09441414 ! S phase GO:0051320 8 8 0,000 0,03780671 0,09431174 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03780671 0,09420956 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,03780671 0,0941076 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03780671 0,09400586 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03780671 0,09390435 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03780671 0,09380305 ! hormone catabolic process GO:0042447 13 8 0,000 0,03780671 0,09370197 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03780671 0,0936011 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03780671 0,09350046 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03780671 0,09340003 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03780671 0,09329981 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03780671 0,09319981 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,03780671 0,09310003 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03780671 0,09300045 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03780671 0,0929011 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03780671 0,09280195 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03780671 0,09270301 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03780671 0,09260429 ! lamellipodium assembly GO:0030032 9 8 0,000 0,03780671 0,09250577 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03780671 0,09240747 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,03780671 0,09230937 ! negative regulation of cell size GO:0045792 108 64 1,000 0,03795475 0,09257257 ! adaptive immune response GO:0002250 94 64 1,000 0,03795475 0,09247451 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! protein oligomerization GO:0051259 100 65 1,000 0,03903993 0,09501781 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,04013686 0,09758434 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,04124543 0,10017371 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 0,0423655 0,1027855 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,04243211 0,10283861 ! telencephalon cell migration GO:0022029 16 9 0,000 0,04243211 0,10273036 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,04243211 0,10262234 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,04243211 0,10251454 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,04243211 0,10240697 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,04243211 0,10229963 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04243211 0,10219251 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,04243211 0,10208561 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,04243211 0,10197894 ! GTP metabolic process GO:0046039 9 9 0,000 0,04243211 0,10187249 ! elastic fiber assembly GO:0048251 13 9 0,000 0,04243211 0,10176626 ! social behavior GO:0035176 14 9 0,000 0,04243211 0,10166025 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,04243211 0,10155447 ! artery development GO:0060840 19 9 0,000 0,04243211 0,1014489 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,04243211 0,10134356 ! response to pain GO:0048265 16 9 0,000 0,04243211 0,10123843 ! protein complex disassembly GO:0043241 17 9 0,000 0,04243211 0,10113352 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,04243211 0,10102882 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,04243211 0,10092435 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,04243211 0,10082009 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,04243211 0,10071604 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,04243211 0,10061221 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,04243211 0,10050859 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,04243211 0,10040519 ! ventral spinal cord development GO:0021517 11 9 0,000 0,04243211 0,100302 ! protein targeting to ER GO:0045047 19 9 0,000 0,04243211 0,10019902 ! T cell selection GO:0045058 18 9 0,000 0,04243211 0,10009625 ! endoderm development GO:0007492 12 9 0,000 0,04243211 0,09999369 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,04243211 0,09989135 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,04243211 0,09978921 ! arginine catabolic process GO:0006527 10 9 0,000 0,04243211 0,09968728 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,04243211 0,09958556 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,04243211 0,09948404 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,04243211 0,09938273 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04243211 0,09928163 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,04243211 0,09918074 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,04243211 0,09908005 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,04243211 0,09897956 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,04243211 0,09887928 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04243211 0,0987792 ! mannose metabolic process GO:0006013 9 9 0,000 0,04243211 0,09867932 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,04243211 0,09857964 ! receptor clustering GO:0043113 15 9 0,000 0,04243211 0,09848017 ! epithelial cell development GO:0002064 10 9 0,000 0,04243211 0,09838089 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,04243211 0,09828182 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,04243211 0,09818294 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,04243211 0,09808427 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,04243211 0,09798579 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,04243211 0,09788751 ! motor axon guidance GO:0008045 14 9 0,000 0,04243211 0,09778942 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,04243211 0,09769154 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,04243211 0,09759384 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,04243211 0,09749635 ! blastoderm segmentation GO:0007350 11 9 0,000 0,04243211 0,09739905 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,04243211 0,09730194 ! DNA ligation GO:0006266 14 9 0,000 0,04243211 0,09720502 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,04243211 0,0971083 ! response to amine stimulus GO:0014075 13 9 0,000 0,04243211 0,09701177 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,04243211 0,09691544 ! erythrocyte development GO:0048821 11 9 0,000 0,04243211 0,09681929 ! renal water homeostasis GO:0003091 14 9 0,000 0,04243211 0,09672333 ! postreplication repair GO:0006301 11 9 0,000 0,04243211 0,09662757 ! mRNA cleavage GO:0006379 13 9 0,000 0,04243211 0,09653199 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,04243211 0,09643661 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,04243211 0,09634141 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,04243211 0,0962464 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,04243211 0,09615157 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,04243211 0,09605693 ! acid secretion GO:0046717 14 9 0,000 0,04243211 0,09596248 ! musculoskeletal movement GO:0050881 11 9 0,000 0,04243211 0,09586822 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,04243211 0,09577414 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,04243211 0,09568024 ! purine base metabolic process GO:0006144 18 9 0,000 0,04243211 0,09558653 ! oocyte differentiation GO:0009994 12 9 0,000 0,04243211 0,095493 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,04243211 0,09539965 ! spleen development GO:0048536 15 9 0,000 0,04243211 0,09530649 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,04243211 0,09521351 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,04243211 0,09512071 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,04243211 0,09502809 ! detection of calcium ion GO:0005513 13 9 0,000 0,04243211 0,09493565 ! blastocyst formation GO:0001825 12 9 0,000 0,04243211 0,09484339 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,04243211 0,09475131 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,04243211 0,0946594 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,04243211 0,09456768 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,04243211 0,09447613 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04243211 0,09438476 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,04243211 0,09429357 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,04243211 0,09420255 ! prepulse inhibition GO:0060134 14 9 0,000 0,04243211 0,09411171 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,04243211 0,09402105 ! insulin secretion GO:0030073 17 9 0,000 0,04243211 0,09393055 ! sequestering of metal ion GO:0051238 11 9 0,000 0,04243211 0,09384024 ! response to nicotine GO:0035094 16 9 0,000 0,04243211 0,09375009 ! establishment of cell polarity GO:0030010 12 9 0,000 0,04243211 0,09366012 ! regulation of synapse organization GO:0050807 12 9 0,000 0,04243211 0,09357032 ! localization within membrane GO:0051668 15 9 0,000 0,04243211 0,09348069 ! eye development GO:0001654 111 70 1,000 0,0446396 0,09824983 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,04703553 0,10342422 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,04703553 0,10332543 ! neuron fate specification GO:0048665 11 10 0,000 0,04703553 0,10322684 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,04703553 0,10312844 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,04703553 0,10303022 ! thyroid gland development GO:0030878 19 10 0,000 0,04703553 0,10293219 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,04703553 0,10283434 ! synapsis GO:0007129 13 10 0,000 0,04703553 0,10273669 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,04703553 0,10263921 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,04703553 0,10254192 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,04703553 0,10244482 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,04703553 0,1023479 ! sulfate transport GO:0008272 12 10 0,000 0,04703553 0,10225116 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,04703553 0,10215461 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,04703553 0,10205824 ! phospholipid efflux GO:0033700 16 10 0,000 0,04703553 0,10196205 ! hippocampus development GO:0021766 19 10 0,000 0,04703553 0,10186604 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,04703553 0,10177021 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,04703553 0,10167456 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,04703553 0,10157909 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,04703553 0,1014838 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,04703553 0,10138869 ! pathogenesis GO:0009405 13 10 0,000 0,04703553 0,10129375 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,04703553 0,101199 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04703553 0,10110442 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,04703553 0,10101002 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,04703553 0,10091579 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,04703553 0,10082174 ! melanocyte differentiation GO:0030318 15 10 0,000 0,04703553 0,10072787 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,04703553 0,10063417 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,04703553 0,10054064 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04703553 0,10044729 ! response to X-ray GO:0010165 16 10 0,000 0,04703553 0,10035411 ! B cell proliferation GO:0042100 14 10 0,000 0,04703553 0,1002611 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,04703553 0,10016827 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,04703553 0,10007561 ! forebrain cell migration GO:0021885 17 10 0,000 0,04703553 0,09998311 ! lipid digestion GO:0044241 15 10 0,000 0,04703553 0,09989079 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,04703553 0,09979864 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,04703553 0,09970666 ! UV protection GO:0009650 14 10 0,000 0,04703553 0,09961485 ! entry into host cell GO:0030260 20 10 0,000 0,04703553 0,09952321 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,04703553 0,09943174 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,04703553 0,09934043 ! negative regulation of ossification GO:0030279 19 10 0,000 0,04703553 0,09924929 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,04703553 0,09915832 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,04703553 0,09906752 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,04703553 0,09897688 ! regulation of organ growth GO:0046620 11 10 0,000 0,04703553 0,09888641 ! response to dsRNA GO:0043331 18 10 0,000 0,04703553 0,0987961 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,04703553 0,09870596 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04703553 0,09861598 ! embryonic axis specification GO:0000578 12 10 0,000 0,04703553 0,09852617 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,04703553 0,09843651 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,04703553 0,09834703 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,04703553 0,0982577 ! cranial nerve development GO:0021545 12 10 0,000 0,04703553 0,09816854 ! fucose catabolic process GO:0019317 16 10 0,000 0,04703553 0,09807954 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,04703553 0,0979907 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,04703553 0,09790202 ! protein sumoylation GO:0016925 12 10 0,000 0,04703553 0,0978135 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,04703553 0,09772514 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04703553 0,09763694 ! zymogen activation GO:0031638 14 10 0,000 0,04703553 0,0975489 ! salivary gland development GO:0007431 22 10 0,000 0,04703553 0,09746102 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04703553 0,09737329 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,04703553 0,09728573 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,04703553 0,09719832 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,04703553 0,09711107 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,04703553 0,09702397 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04703553 0,09693703 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,04703553 0,09685025 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,04703553 0,09676362 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,04703553 0,09667715 ! detection of bacterium GO:0016045 10 10 0,000 0,04703553 0,09659083 ! embryonic gut development GO:0048566 11 10 0,000 0,04703553 0,09650467 ! activation of innate immune response GO:0002218 10 10 0,000 0,04703553 0,09641865 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,04703553 0,0963328 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,04703553 0,09624709 ! developmental induction GO:0031128 13 10 0,000 0,04703553 0,09616154 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,04703553 0,09607614 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,04703553 0,09599089 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,04703553 0,09590579 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,04703553 0,09582084 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,04931997 0,10038578 ! blood coagulation GO:0007596 116 75 1,000 0,05051685 0,10273099 GO:0050817|coagulation, ! rRNA transcription GO:0009303 17 11 0,000 0,05161709 0,10487572 ! respiratory burst GO:0045730 14 11 0,000 0,05161709 0,10478316 ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,05161709 0,10469076 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,05161709 0,10459852 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,05161709 0,10450644 GO:0000725|recombinational repair, ! Golgi vesicle budding GO:0048194 17 11 0,000 0,05161709 0,10441453 ! RNA polyadenylation GO:0043631 19 11 0,000 0,05161709 0,10432277 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,05161709 0,10423118 ! mating GO:0007618 14 11 0,000 0,05161709 0,10413975 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,05161709 0,10404848 ! T cell proliferation GO:0042098 20 11 0,000 0,05161709 0,10395737 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,05161709 0,10386642 ! bone resorption GO:0045453 16 11 0,000 0,05161709 0,10377563 ! regulated secretory pathway GO:0045055 14 11 0,000 0,05161709 0,10368499 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,05161709 0,10359452 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,05161709 0,1035042 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,05161709 0,10341404 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,05161709 0,10332404 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,05161709 0,10323419 ! syncytium formation GO:0006949 15 11 0,000 0,05161709 0,1031445 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,05161709 0,10305496 ! mitotic spindle organization GO:0007052 15 11 0,000 0,05161709 0,10296558 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,05161709 0,10287636 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,05161709 0,10278729 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,05161709 0,10269837 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,05161709 0,10260961 ! adult heart development GO:0007512 11 11 0,000 0,05161709 0,102521 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,05161709 0,10243254 ! temperature homeostasis GO:0001659 16 11 0,000 0,05161709 0,10234424 ! L-glutamate transport GO:0015813 16 11 0,000 0,05161709 0,10225609 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,05161709 0,10216809 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,05161709 0,10208024 ! stem cell development GO:0048864 29 11 0,000 0,05161709 0,10199254 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,05161709 0,10190499 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,05161709 0,1018176 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,05161709 0,10173035 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,05161709 0,10164325 ! vasoconstriction GO:0042310 15 11 0,000 0,05161709 0,1015563 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,05161709 0,1014695 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,05161709 0,10138285 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,05161709 0,10129635 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,05161709 0,10120999 ! ribosome assembly GO:0042255 13 11 0,000 0,05161709 0,10112378 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,05161709 0,10103772 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,05161709 0,1009518 ! chromatin silencing GO:0006342 19 11 0,000 0,05161709 0,10086603 ! nucleosome positioning GO:0016584 13 11 0,000 0,05161709 0,10078041 ! T cell homeostasis GO:0043029 20 11 0,000 0,05161709 0,10069493 ! regulation of isotype switching GO:0045191 19 11 0,000 0,05161709 0,10060959 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,05161709 0,1005244 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,05161709 0,10043936 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,05161709 0,10035445 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,05161709 0,10026969 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,05161709 0,10018508 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,05161709 0,10010061 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,05161709 0,10001627 ! male genitalia development GO:0030539 13 11 0,000 0,05161709 0,09993209 ! cholesterol efflux GO:0033344 19 11 0,000 0,05161709 0,09984804 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,05161709 0,09976413 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,05161709 0,09968037 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,05161709 0,09959674 ! germ cell migration GO:0008354 18 11 0,000 0,05161709 0,09951326 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,05161709 0,09942991 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,05161709 0,09934671 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,05161709 0,09926364 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,05161709 0,09918072 ! lysogeny GO:0030069 18 11 0,000 0,05161709 0,09909793 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,05161709 0,09901528 ! acrosome reaction GO:0007340 13 11 0,000 0,05161709 0,09893276 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,05161709 0,09885039 ! tRNA metabolic process GO:0006399 95 76 1,000 0,05172418 0,09897307 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,05172418 0,09889079 ! lactation GO:0007595 20 12 0,000 0,05617689 0,10731465 ! reproductive cellular process GO:0048610 14 12 0,000 0,05617689 0,1072256 ! tRNA modification GO:0006400 14 12 0,000 0,05617689 0,10713669 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,05617689 0,10704792 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,05617689 0,10695931 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,05617689 0,10687084 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,05617689 0,10678252 ! non-recombinational repair GO:0000726 19 12 0,000 0,05617689 0,10669434 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,05617689 0,10660631 ! peroxisomal transport GO:0043574 21 12 0,000 0,05617689 0,10651842 ! cartilage condensation GO:0001502 18 12 0,000 0,05617689 0,10643068 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,05617689 0,10634308 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,05617689 0,10625563 ! palate development GO:0060021 15 12 0,000 0,05617689 0,10616832 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,05617689 0,10608115 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,05617689 0,10599413 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,05617689 0,10590725 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,05617689 0,10582051 ! arginine metabolic process GO:0006525 13 12 0,000 0,05617689 0,10573392 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,05617689 0,10564746 ! methionine metabolic process GO:0006555 13 12 0,000 0,05617689 0,10556115 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,05617689 0,10547497 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,05617689 0,10538894 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,05617689 0,10530305 ! monoamine transport GO:0015844 13 12 0,000 0,05617689 0,1052173 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05617689 0,10513169 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,05617689 0,10504621 ! L-amino acid transport GO:0015807 20 12 0,000 0,05617689 0,10496088 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,05617689 0,10487569 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,05617689 0,10479063 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,05617689 0,10470571 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05617689 0,10462093 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,05617689 0,10453628 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,05617689 0,10445177 ! cerebellum development GO:0021549 13 12 0,000 0,05617689 0,1043674 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,05617689 0,10428317 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,05617689 0,10419907 ! histone methylation GO:0016571 15 12 0,000 0,05617689 0,1041151 ! autonomic nervous system development GO:0048483 23 12 0,000 0,05617689 0,10403128 ! gland morphogenesis GO:0022612 23 12 0,000 0,05617689 0,10394758 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,05617689 0,10386402 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,05617689 0,1037806 ! response to gamma radiation GO:0010332 20 12 0,000 0,05617689 0,10369731 ! regulation of epidermis development GO:0045682 17 12 0,000 0,05617689 0,10361415 ! intestinal absorption GO:0050892 19 12 0,000 0,05617689 0,10353113 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,05617689 0,10344823 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,05617689 0,10336548 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,05617689 0,10328285 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,05617689 0,10320035 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,05617689 0,10311799 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,05617689 0,10303576 ! response to cold GO:0009409 14 12 0,000 0,05617689 0,10295366 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,05665563 0,10374838 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 1,000 0,05665563 0,10366584 ! forebrain development GO:0030900 131 80 1,000 0,05665563 0,10358343 ! hemostasis GO:0007599 125 81 1,000 0,05791341 0,10579892 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,05791341 0,10571495 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,0591809 0,10794296 GO:0060348|bone development, ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,06071502 0,11065336 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,06071502 0,11056575 ! cGMP metabolic process GO:0046068 16 13 0,000 0,06071502 0,11047828 GO:0006182|cGMP biosynthetic process, ! water transport GO:0006833 17 13 0,000 0,06071502 0,11039094 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,06071502 0,11030375 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,06071502 0,11021669 ! lipid localization GO:0010876 24 13 0,000 0,06071502 0,11012977 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,06071502 0,11004298 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,06071502 0,10995633 ! organelle fusion GO:0048284 28 13 0,000 0,06071502 0,10986982 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,06071502 0,10978345 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,06071502 0,10969721 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,06071502 0,1096111 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,06071502 0,10952513 ! response to hexose stimulus GO:0009746 19 13 0,000 0,06071502 0,1094393 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,06071502 0,1093536 ! glutamate metabolic process GO:0006536 18 13 0,000 0,06071502 0,10926803 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,06071502 0,1091826 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,06071502 0,1090973 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,06071502 0,10901213 ! NAD metabolic process GO:0019674 21 13 0,000 0,06071502 0,1089271 ! exocrine system development GO:0035272 27 13 0,000 0,06071502 0,1088422 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,06071502 0,10875743 ! bone mineralization GO:0030282 15 13 0,000 0,06071502 0,1086728 ! regulation of exocytosis GO:0017157 17 13 0,000 0,06071502 0,10858829 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,06071502 0,10850392 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,06071502 0,10841968 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,06071502 0,10833557 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,06071502 0,10825159 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,06071502 0,10816773 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,06071502 0,10808401 ! genitalia development GO:0048806 15 13 0,000 0,06071502 0,10800042 ! regulation of cellular pH GO:0030641 20 13 0,000 0,06071502 0,10791696 ! cellular pigmentation GO:0033059 24 13 0,000 0,06071502 0,10783363 ! tissue regeneration GO:0042246 21 13 0,000 0,06071502 0,10775042 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,06071502 0,10766734 ! cofactor transport GO:0051181 19 13 0,000 0,06071502 0,10758439 ! NADP metabolic process GO:0006739 18 13 0,000 0,06071502 0,10750157 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,06071502 0,10741888 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,06071502 0,10733631 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06071502 0,10725387 ! gas transport GO:0015669 18 13 0,000 0,06071502 0,10717156 ! heme biosynthetic process GO:0006783 20 13 0,000 0,06071502 0,10708937 ! regulation of axon extension GO:0030516 23 13 0,000 0,06071502 0,10700731 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,06071502 0,10692538 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,06071502 0,10684357 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,06071502 0,10676188 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,06071502 0,10668032 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,06071502 0,10659889 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,06071502 0,10651758 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,06304051 0,11051309 ! cell cycle arrest GO:0007050 150 86 1,000 0,0643457 0,11271524 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,06523159 0,1141801 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,06523159 0,11409327 ! superoxide anion generation GO:0042554 18 14 0,000 0,06523159 0,11400657 ! neuron maturation GO:0042551 21 14 0,000 0,06523159 0,11392001 ! regulation of S phase GO:0033261 18 14 0,000 0,06523159 0,11383358 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,06523159 0,11374727 ! myotube differentiation GO:0014902 21 14 0,000 0,06523159 0,1136611 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,06523159 0,11357506 ! inositol metabolic process GO:0006020 20 14 0,000 0,06523159 0,11348915 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,06523159 0,11340337 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,06523159 0,11331771 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,06523159 0,11323219 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,06523159 0,1131468 ! gene silencing by RNA GO:0031047 20 14 0,000 0,06523159 0,11306153 ! response to cAMP GO:0051591 19 14 0,000 0,06523159 0,1129764 ! limbic system development GO:0021761 25 14 0,000 0,06523159 0,11289139 ! startle response GO:0001964 21 14 0,000 0,06523159 0,11280651 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,06523159 0,11272175 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,06523159 0,11263713 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,06523159 0,11255263 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,06523159 0,11246826 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,06523159 0,11238401 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,06523159 0,11229989 ! glycine metabolic process GO:0006544 22 14 0,000 0,06523159 0,1122159 ! cellular response to starvation GO:0009267 21 14 0,000 0,06523159 0,11213203 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,06523159 0,11204828 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,06523159 0,11196467 ! regulation of heart rate GO:0002027 23 14 0,000 0,06523159 0,11188117 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,06523159 0,1117978 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,06523159 0,11171456 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,06523159 0,11163144 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,06523159 0,11154844 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,06523159 0,11146557 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,06523159 0,11138282 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,06523159 0,11130019 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,06523159 0,11121768 ! axon cargo transport GO:0008088 27 14 0,000 0,06523159 0,1111353 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,06523159 0,11105304 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,06523159 0,1109709 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,06523159 0,11088888 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,06523159 0,11080698 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06523159 0,1107252 ! mRNA splice site selection GO:0006376 26 14 0,000 0,06523159 0,11064355 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,06523159 0,11056201 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,06523159 0,1104806 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,06523159 0,1103993 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,06523159 0,11031813 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,06523159 0,11023707 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,06523159 0,11015613 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,06523159 0,11007531 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,06523159 0,10999461 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,06523159 0,10991403 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,06523159 0,10983357 ! cell killing GO:0001906 20 14 0,000 0,06523159 0,10975322 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,06523159 0,10967299 ! cilium assembly GO:0042384 20 14 0,000 0,06523159 0,10959288 ! peptide hormone secretion GO:0030072 23 14 0,000 0,06523159 0,10951289 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,06566002 0,11015174 GO:0060538|skeletal muscle organ development, ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,06698335 0,11228987 ! reproductive developmental process GO:0003006 127 89 1,000 0,06831558 0,1144398 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,06831558 0,11435651 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,0697267 0,11663375 ! positive regulation of cell size GO:0045793 20 15 0,000 0,0697267 0,11654898 ! metencephalon development GO:0022037 19 15 0,000 0,0697267 0,11646434 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,0697267 0,11637983 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,0697267 0,11629543 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,0697267 0,11621116 ! skin development GO:0043588 25 15 0,000 0,0697267 0,11612701 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,0697267 0,11604298 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,0697267 0,11595908 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,0697267 0,11587529 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,0697267 0,11579163 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,0697267 0,11570808 ! bile acid metabolic process GO:0008206 22 15 0,000 0,0697267 0,11562466 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,0697267 0,11554136 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,0697267 0,11545817 ! adult walking behavior GO:0007628 25 15 0,000 0,0697267 0,11537511 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,0697267 0,11529216 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,0697267 0,11520934 ! myoblast differentiation GO:0045445 27 15 0,000 0,0697267 0,11512663 ! centrosome cycle GO:0007098 16 15 0,000 0,0697267 0,11504405 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,0697267 0,11496158 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,0697267 0,11487923 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,0697267 0,11479699 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,0697267 0,11471488 ! cerebral cortex development GO:0021987 29 15 0,000 0,0697267 0,11463288 ! response to osmotic stress GO:0006970 22 15 0,000 0,0697267 0,114551 ! vesicle coating GO:0006901 25 15 0,000 0,0697267 0,11446924 ! DNA integration GO:0015074 22 15 0,000 0,0697267 0,11438759 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,0697267 0,11430606 ! peptide secretion GO:0002790 27 15 0,000 0,0697267 0,11422464 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,0697267 0,11414335 ! regulation of vasodilation GO:0042312 24 15 0,000 0,0697267 0,11406216 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,0697267 0,1139811 ! neuron recognition GO:0008038 22 15 0,000 0,0697267 0,11390014 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,0697267 0,11381931 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,0697267 0,11373858 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,0697267 0,11365797 ! biomineral formation GO:0031214 18 15 0,000 0,0697267 0,11357748 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,0697267 0,1134971 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,0697267 0,11341683 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,0697267 0,11333668 ! dopamine metabolic process GO:0042417 30 15 0,000 0,0697267 0,11325664 ! organic cation transport GO:0015695 19 15 0,000 0,0697267 0,11317671 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,0697267 0,1130969 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,0697267 0,1130172 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,0697267 0,11293761 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,0697267 0,11285813 ! defense response to virus GO:0051607 27 15 0,000 0,0697267 0,11277876 ! peptide hormone processing GO:0016486 19 15 0,000 0,0697267 0,11269951 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,0697267 0,11262037 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,07236455 0,11679893 ! cell fate commitment GO:0045165 141 92 1,000 0,07236455 0,11671702 ! protein secretion GO:0009306 27 16 0,000 0,07420044 0,11959427 ! hormone secretion GO:0046879 25 16 0,000 0,07420044 0,11951052 ! bone remodeling GO:0046849 24 16 0,000 0,07420044 0,11942689 ! endothelial cell migration GO:0043542 22 16 0,000 0,07420044 0,11934337 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,07420044 0,11925997 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07420044 0,11917669 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,07420044 0,11909353 ! glial cell development GO:0021782 24 16 0,000 0,07420044 0,11901048 ! patterning of blood vessels GO:0001569 24 16 0,000 0,07420044 0,11892754 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,07420044 0,11884472 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,07420044 0,11876202 ! protein polyubiquitination GO:0000209 26 16 0,000 0,07420044 0,11867943 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,07420044 0,11859696 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,07420044 0,1185146 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,07420044 0,11843235 ! fructose metabolic process GO:0006000 20 16 0,000 0,07420044 0,11835022 ! regulation of protein binding GO:0043393 27 16 0,000 0,07420044 0,11826821 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,07420044 0,1181863 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,07420044 0,11810451 ! protein export from nucleus GO:0006611 24 16 0,000 0,07420044 0,11802284 ! negative regulation of immune response GO:0050777 28 16 0,000 0,07420044 0,11794127 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,07420044 0,11785982 ! DNA replication initiation GO:0006270 25 16 0,000 0,07420044 0,11777848 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,07420044 0,11769726 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,07420044 0,11761614 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,07420044 0,11753514 ! oogenesis GO:0048477 23 16 0,000 0,07420044 0,11745425 ! G1 phase GO:0051318 27 16 0,000 0,07420044 0,11737347 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,07420044 0,1172928 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,07420044 0,11721224 ! steroid catabolic process GO:0006706 22 16 0,000 0,07420044 0,11713179 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,07420044 0,11705146 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,07420044 0,11697123 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,07420044 0,11689111 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,07420044 0,1168111 ! sperm-egg recognition GO:0035036 16 16 0,000 0,07420044 0,1167312 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,07420044 0,11665142 ! nerve development GO:0021675 18 16 0,000 0,07420044 0,11657174 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,07420044 0,11649216 ! negative regulation of translation GO:0017148 22 16 0,000 0,07420044 0,1164127 ! response to oxidative stress GO:0006979 141 94 1,000 0,07510631 0,11775358 ! angiogenesis GO:0001525 149 95 1,000 0,07648959 0,11984063 ! in utero embryonic development GO:0001701 147 96 1,000 0,07788099 0,12193756 ! response to light stimulus GO:0009416 153 96 1,000 0,07788099 0,12185461 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,07865293 0,12297875 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,07865293 0,12289521 ! negative regulation of defense response GO:0031348 19 17 0,000 0,07865293 0,12281178 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,07865293 0,12272846 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,07865293 0,12264525 ! glycerol metabolic process GO:0006071 20 17 0,000 0,07865293 0,12256216 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,07865293 0,12247918 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,07865293 0,12239631 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,07865293 0,12231355 ! signal complex assembly GO:0007172 29 17 0,000 0,07865293 0,12223091 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,07865293 0,12214838 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,07865293 0,12206595 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,07865293 0,12198364 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,07865293 0,12190145 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,07865293 0,12181936 ! memory GO:0007613 25 17 0,000 0,07865293 0,12173738 ! keratinization GO:0031424 17 17 0,000 0,07865293 0,12165551 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,07865293 0,12157375 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,07865293 0,12149211 ! retinoid metabolic process GO:0001523 22 17 0,000 0,07865293 0,12141057 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,07865293 0,12132914 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,07865293 0,12124782 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,07865293 0,12116661 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,07865293 0,12108551 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,07865293 0,12100451 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,07865293 0,12092363 ! membrane budding GO:0006900 29 17 0,000 0,07865293 0,12084285 ! heme metabolic process GO:0042168 27 17 0,000 0,07865293 0,12076218 ! neuromuscular junction development GO:0007528 23 17 0,000 0,07865293 0,12068162 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,07865293 0,12060116 ! body fluid secretion GO:0007589 27 17 0,000 0,07865293 0,12052082 ! stem cell differentiation GO:0048863 36 17 0,000 0,07865293 0,12044058 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,07865293 0,12036044 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,07865293 0,12028042 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,07865293 0,12020049 ! sensory perception of pain GO:0019233 23 17 0,000 0,07865293 0,12012068 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,07865293 0,12004097 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,07865293 0,11996137 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,07865293 0,11988187 ! synaptogenesis GO:0007416 24 17 0,000 0,07865293 0,11980248 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,07865293 0,11972319 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,07865293 0,11964401 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,07865293 0,11956493 ! cell-cell junction organization GO:0045216 25 17 0,000 0,07865293 0,11948596 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,07865293 0,11940709 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,07865293 0,11932833 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,07865293 0,11924967 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,07865293 0,11917111 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,07865293 0,11909266 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,08308426 0,12571961 ! positive regulation of translation GO:0045727 28 18 0,000 0,08308426 0,12563695 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,08308426 0,1255544 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,08308426 0,12547196 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,08308426 0,12538963 ! cAMP metabolic process GO:0046058 33 18 0,000 0,08308426 0,12530741 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,08308426 0,1252253 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,08308426 0,12514329 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,08308426 0,12506139 ! axis specification GO:0009798 26 18 0,000 0,08308426 0,12497959 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,08308426 0,12489791 GO:0050886|endocrine process, ! pancreas development GO:0031016 26 18 0,000 0,08308426 0,12481633 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,08308426 0,12473486 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,08308426 0,12465349 ! glutamine metabolic process GO:0006541 23 18 0,000 0,08308426 0,12457223 ! central nervous system neuron development GO:0021954 30 18 0,000 0,08308426 0,12449108 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,08308426 0,12441003 ! fucose metabolic process GO:0006004 26 18 0,000 0,08308426 0,12432908 ! response to fungus GO:0009620 19 18 0,000 0,08308426 0,12424824 ! peptide cross-linking GO:0018149 31 18 0,000 0,08308426 0,12416751 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,08308426 0,12408688 ! heart process GO:0003015 27 18 0,000 0,08308426 0,12400636 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,08308426 0,12392594 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,08308426 0,12384563 ! visual learning GO:0008542 35 18 0,000 0,08308426 0,12376541 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,08308426 0,12368531 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,08308426 0,1236053 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,08308426 0,1235254 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,08308426 0,12344561 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,08308426 0,12336591 ! vitamin transport GO:0051180 24 18 0,000 0,08308426 0,12328632 ! hormone transport GO:0009914 27 18 0,000 0,08308426 0,12320683 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,08308426 0,12312745 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,08308426 0,12304817 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,08308426 0,12296898 ! cell-cell recognition GO:0009988 20 18 0,000 0,08308426 0,1228899 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,08308426 0,12281093 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,08308426 0,12273205 ! gut development GO:0048565 26 18 0,000 0,08308426 0,12265327 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,08308426 0,1225746 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,08308426 0,12249603 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,08308426 0,12241755 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,08352567 0,12298915 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,08352567 0,12291046 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,08749453 0,12866843 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,08749453 0,12858621 ! positive regulation of ossification GO:0045778 30 19 0,000 0,08749453 0,1285041 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,08749453 0,12842209 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,08749453 0,12834019 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,08749453 0,12825839 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,08749453 0,1281767 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,08749453 0,12809511 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,08749453 0,12801362 ! regeneration GO:0031099 32 19 0,000 0,08749453 0,12793224 ! response to alkaloid GO:0043279 32 19 0,000 0,08749453 0,12785096 ! sensory perception of taste GO:0050909 23 19 0,000 0,08749453 0,12776979 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,08749453 0,12768872 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,08749453 0,12760775 ! smooth muscle contraction GO:0006939 36 19 0,000 0,08749453 0,12752688 ! peroxisome organization GO:0007031 29 19 0,000 0,08749453 0,12744612 ! digestive system process GO:0022600 30 19 0,000 0,08749453 0,12736545 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,08749453 0,12728489 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,08749453 0,12720444 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,08749453 0,12712408 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,08749453 0,12704382 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,08749453 0,12696367 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,08749453 0,12688362 ! response to starvation GO:0042594 30 19 0,000 0,08749453 0,12680367 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,08749453 0,12672381 ! cytolysis GO:0019835 20 19 0,000 0,08749453 0,12664406 ! renal system process GO:0003014 35 19 0,000 0,08749453 0,12656441 ! vasodilation GO:0042311 33 19 0,000 0,08749453 0,12648486 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,08749453 0,12640541 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,08749453 0,12632606 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,08749453 0,12624681 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,08749453 0,12616766 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,08749453 0,12608861 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,08749453 0,12600965 ! sarcomere organization GO:0045214 23 19 0,000 0,08749453 0,1259308 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,08749453 0,12585204 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,08749453 0,12577339 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,08749453 0,12569483 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,08749453 0,12561637 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,08749453 0,125538 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,08749453 0,12545974 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,08749453 0,12538157 ! protein stabilization GO:0050821 26 19 0,000 0,08749453 0,1253035 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,09188384 0,13150767 ! iron ion transport GO:0006826 37 20 0,000 0,09188384 0,13142588 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,09188384 0,1313442 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,09188384 0,13126262 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,09188384 0,13118114 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,09188384 0,13109977 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,09188384 0,13101849 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,09188384 0,13093731 ! spinal cord development GO:0021510 31 20 0,000 0,09188384 0,13085624 ! response to ethanol GO:0045471 37 20 0,000 0,09188384 0,13077526 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,09188384 0,13069439 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,09188384 0,13061361 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,09188384 0,13053294 ! chromosome condensation GO:0030261 31 20 0,000 0,09188384 0,13045236 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,09188384 0,13037188 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,09188384 0,13029151 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,09188384 0,13021123 ! pallium development GO:0021543 38 20 0,000 0,09188384 0,13013105 ! DNA modification GO:0006304 28 20 0,000 0,09188384 0,13005097 ! collagen fibril organization GO:0030199 45 20 0,000 0,09188384 0,12997099 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,09188384 0,1298911 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,09188384 0,12981132 ! collagen catabolic process GO:0030574 25 20 0,000 0,09188384 0,12973163 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,09188384 0,12965204 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,09188384 0,12957255 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,09188384 0,12949315 ! alditol metabolic process GO:0019400 24 20 0,000 0,09188384 0,12941385 ! actin filament-based movement GO:0030048 34 20 0,000 0,09188384 0,12933465 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,09625228 0,13540076 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,09625228 0,135318 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,09625228 0,13523533 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,09625228 0,13515277 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,09625228 0,13507031 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,09625228 0,13498795 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,09625228 0,13490569 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,09625228 0,13482353 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,09625228 0,13474147 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,09625228 0,13465951 ! vesicle docking GO:0048278 27 21 0,000 0,09625228 0,13457765 ! phototransduction GO:0007602 25 21 0,000 0,09625228 0,13449589 ! dendrite development GO:0016358 35 21 0,000 0,09625228 0,13441423 ! visual behavior GO:0007632 39 21 0,000 0,09625228 0,13433267 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,09625228 0,13425121 ! ovarian follicle development GO:0001541 30 21 0,000 0,09625228 0,13416984 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,09625228 0,13408858 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,09625228 0,13400741 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,09625228 0,13392634 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,09625228 0,13384537 ! cell aging GO:0007569 32 21 0,000 0,09625228 0,1337645 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,09625228 0,13368372 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,09625228 0,13360304 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,09625228 0,13352246 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,09625228 0,13344198 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,09625228 0,13336159 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,09625228 0,1332813 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,09625228 0,13320111 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,09625228 0,13312101 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,09625228 0,13304101 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,09625228 0,13296111 ! fatty acid transport GO:0015908 30 21 0,000 0,09625228 0,1328813 ! immunoglobulin production GO:0002377 33 21 0,000 0,09625228 0,13280158 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,09625228 0,13272197 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,09625228 0,13264245 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,09625228 0,13256302 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,09625228 0,13248369 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,09625228 0,13240445 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,09625228 0,13232531 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,09625228 0,13224626 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,09625228 0,13216731 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,09625228 0,13208845 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,09625228 0,13200969 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,09625228 0,13193101 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,09625228 0,13185244 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,09625228 0,13177395 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,10059996 0,1376442 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,10059996 0,13756237 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,10059996 0,13748063 ! viral genome replication GO:0019079 29 22 0,000 0,10059996 0,13739899 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,10059996 0,13731745 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,10059996 0,137236 ! leukocyte adhesion GO:0007159 38 22 0,000 0,10059996 0,13715465 ! molting cycle process GO:0022404 40 22 0,000 0,10059996 0,1370734 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,10059996 0,13699224 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,10059996 0,13691118 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,10059996 0,13683022 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,10059996 0,13674935 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,10059996 0,13666858 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,10059996 0,1365879 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,10059996 0,13650732 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,10059996 0,13642683 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,10059996 0,13634644 ! lysosome organization GO:0007040 37 22 0,000 0,10059996 0,13626614 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,10059996 0,13618593 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,10059996 0,13610582 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,10059996 0,13602581 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,10059996 0,13594589 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,10059996 0,13586606 ! membrane depolarization GO:0051899 35 22 0,000 0,10059996 0,13578633 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,10059996 0,13570669 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,10059996 0,13562714 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,10059996 0,13554769 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,10059996 0,13546833 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,10059996 0,13538906 ! blastocyst development GO:0001824 37 22 0,000 0,10059996 0,13530988 ! neural tube closure GO:0001843 33 22 0,000 0,10059996 0,1352308 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,10059996 0,13515181 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,10492697 0,14088268 ! embryonic pattern specification GO:0009880 31 23 0,000 0,10492697 0,14080048 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,10492697 0,14071838 ! myelination GO:0042552 35 23 0,000 0,10492697 0,14063638 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,10492697 0,14055447 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,10492697 0,14047266 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,10492697 0,14039094 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,10492697 0,14030932 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,10492697 0,14022779 ! vesicle targeting GO:0006903 32 23 0,000 0,10492697 0,14014636 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,10492697 0,14006502 ! osteoblast differentiation GO:0001649 40 23 0,000 0,10492697 0,13998377 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,10492697 0,13990262 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,10492697 0,13982157 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,10492697 0,13974061 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,10492697 0,13965974 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,10492697 0,13957896 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,10492697 0,13949828 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,10492697 0,13941769 ! pentose metabolic process GO:0019321 31 23 0,000 0,10492697 0,1393372 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,10492697 0,1392568 ! spermatid development GO:0007286 33 23 0,000 0,10492697 0,13917649 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,10492697 0,13909627 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,10492697 0,13901614 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,10492697 0,13893611 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,10492697 0,13885617 ! telomere organization GO:0032200 32 23 0,000 0,10492697 0,13877632 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,10492697 0,13869657 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,10492697 0,1386169 ! regulation of amine transport GO:0051952 38 23 0,000 0,10492697 0,13853733 ! initiation of viral infection GO:0019059 42 24 0,000 0,10923341 0,14414047 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,10923341 0,14405782 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,10923341 0,14397527 ! superoxide metabolic process GO:0006801 32 24 0,000 0,10923341 0,14389281 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,10923341 0,14381044 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,10923341 0,14372817 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,10923341 0,14364599 ! sperm motility GO:0030317 27 24 0,000 0,10923341 0,14356391 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,10923341 0,14348192 ! vacuole organization GO:0007033 39 24 0,000 0,10923341 0,14340002 ! receptor metabolic process GO:0043112 37 24 0,000 0,10923341 0,14331822 ! response to toxin GO:0009636 38 24 0,000 0,10923341 0,14323651 ! primary neural tube formation GO:0014020 35 24 0,000 0,10923341 0,14315489 ! negative regulation of cell development GO:0010721 56 24 0,000 0,10923341 0,14307337 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,10923341 0,14299194 ! base-excision repair GO:0006284 31 24 0,000 0,10923341 0,1429106 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,10923341 0,14282936 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,10923341 0,1427482 ! glutathione metabolic process GO:0006749 29 24 0,000 0,10923341 0,14266714 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,10923341 0,14258617 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,10923341 0,1425053 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,10923341 0,14242451 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,11351937 0,14792893 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,11351937 0,14784516 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,11351937 0,14776149 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,11351937 0,14767792 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,11351937 0,14759444 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,11351937 0,14751105 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,11351937 0,14742776 ! peptide transport GO:0015833 43 25 0,000 0,11351937 0,14734456 ! male gonad development GO:0008584 33 25 0,000 0,11351937 0,14726145 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,11351937 0,14717844 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,11351937 0,14709553 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,11351937 0,1470127 ! phospholipid transport GO:0015914 35 25 0,000 0,11351937 0,14692997 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,11351937 0,14684733 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,11351937 0,14676479 ! detection of light stimulus GO:0009583 30 25 0,000 0,11351937 0,14668234 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,11351937 0,14659998 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,11351937 0,14651771 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,11351937 0,14643554 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,11778496 0,15185281 ! translational initiation GO:0006413 43 26 0,000 0,11778496 0,15176774 ! regulation of pH GO:0006885 36 26 0,000 0,11778496 0,15168276 ! circadian rhythm GO:0007623 42 26 0,000 0,11778496 0,15159788 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,11778496 0,15151309 ! post-embryonic development GO:0009791 42 26 0,000 0,11778496 0,1514284 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,11778496 0,15134381 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,11778496 0,1512593 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,11778496 0,1511749 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,11778496 0,15109058 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,11778496 0,15100636 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,11778496 0,15092224 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,11778496 0,1508382 ! regulation of coagulation GO:0050818 39 26 0,000 0,11778496 0,15075426 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,12203027 0,15610101 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,12203027 0,15601424 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,12203027 0,15592756 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,12203027 0,15584099 ! membrane docking GO:0022406 39 27 0,000 0,12203027 0,1557545 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,12203027 0,15566812 ! catechol metabolic process GO:0009712 43 27 0,000 0,12203027 0,15558183 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,12203027 0,15549563 ! acute-phase response GO:0006953 42 27 0,000 0,12203027 0,15540953 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,12203027 0,15532353 ! myofibril assembly GO:0030239 36 27 0,000 0,12203027 0,15523762 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,12203027 0,15515181 ! response to ionizing radiation GO:0010212 47 27 0,000 0,12203027 0,15506609 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,12203027 0,15498046 ! natural killer cell activation GO:0030101 35 27 0,000 0,12203027 0,15489493 ! lipid oxidation GO:0034440 38 27 0,000 0,12203027 0,1548095 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,12203027 0,15472415 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,12203027 0,15463891 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,12203027 0,15455375 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,12203027 0,15446869 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,12203027 0,15438373 ! gene silencing GO:0016458 41 27 0,000 0,12203027 0,15429885 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,12625539 0,15955351 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,12625539 0,15946589 ! phenol metabolic process GO:0018958 44 28 0,000 0,12625539 0,15937837 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,12625539 0,15929094 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,12625539 0,15920361 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,12625539 0,15911638 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,12625539 0,15902924 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,12625539 0,1589422 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,12625539 0,15885525 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,12625539 0,15876839 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,12625539 0,15868163 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,12625539 0,15859497 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,12625539 0,1585084 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,12625539 0,15842193 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,12625539 0,15833555 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,12625539 0,15824926 ! mesoderm formation GO:0001707 46 28 0,000 0,12625539 0,15816307 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,12625539 0,15807697 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,12625539 0,15799096 ! ensheathment of neurons GO:0007272 43 28 0,000 0,12625539 0,15790505 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,12625539 0,15781923 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,12625539 0,15773351 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,12625539 0,15764788 ! neural tube formation GO:0001841 41 28 0,000 0,12625539 0,15756234 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,13046041 0,16272178 ! regulation of innate immune response GO:0045088 38 29 0,000 0,13046041 0,16263358 ! ovulation cycle process GO:0022602 41 29 0,000 0,13046041 0,16254548 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,13046041 0,16245747 ! protein targeting to membrane GO:0006612 53 29 0,000 0,13046041 0,16236956 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,13046041 0,16228175 ! mismatch repair GO:0006298 34 29 0,000 0,13046041 0,16219403 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,13046041 0,1621064 ! muscle cell development GO:0055001 38 29 0,000 0,13046041 0,16201887 ! formation of primary germ layer GO:0001704 48 29 0,000 0,13046041 0,16193144 ! telencephalon development GO:0021537 52 29 0,000 0,13046041 0,1618441 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,13046041 0,16175685 ! eye morphogenesis GO:0048592 51 29 0,000 0,13046041 0,16166969 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,13046041 0,16158264 ! tissue homeostasis GO:0001894 42 29 0,000 0,13046041 0,16149567 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,13464544 0,16658662 ! organic anion transport GO:0015711 51 30 0,000 0,13464544 0,16649705 ! cholesterol transport GO:0030301 46 30 0,000 0,13464544 0,16640759 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,13464544 0,16631822 ! spliceosome assembly GO:0000245 49 30 0,000 0,13464544 0,16622894 ! spindle organization GO:0007051 37 30 0,000 0,13464544 0,16613977 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,13464544 0,16605068 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,13464544 0,16596169 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,13464544 0,1658728 ! ceramide metabolic process GO:0006672 43 30 0,000 0,13464544 0,16578401 ! ovulation cycle GO:0042698 43 30 0,000 0,13464544 0,1656953 ! hindbrain development GO:0030902 45 30 0,000 0,13464544 0,1656067 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,13464544 0,16551818 ! adult locomotory behavior GO:0008344 47 30 0,000 0,13464544 0,16542977 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,13464544 0,16534144 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,13464544 0,16525321 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,13464544 0,16516508 ! response to heat GO:0009408 41 30 0,000 0,13464544 0,16507704 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,13464544 0,16498909 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,13464544 0,16490124 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,13881057 0,16991182 ! negative regulation of secretion GO:0051048 49 31 0,000 0,13881057 0,16982144 ! mammary gland development GO:0030879 57 31 0,000 0,13881057 0,16973116 ! glial cell differentiation GO:0010001 55 31 0,000 0,13881057 0,16964097 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,13881057 0,16955088 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,13881057 0,16946089 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,13881057 0,16937099 ! odontogenesis GO:0042476 50 31 0,000 0,13881057 0,16928118 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,13881057 0,16919147 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,13881057 0,16910186 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,13881057 0,16901234 ! metanephros development GO:0001656 58 31 0,000 0,13881057 0,16892292 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,13881057 0,16883359 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,13881057 0,16874435 ! cell fate specification GO:0001708 37 31 0,000 0,13881057 0,16865521 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,13881057 0,16856616 ! RNA modification GO:0009451 40 31 0,000 0,13881057 0,16847721 ! regulation of muscle development GO:0048634 48 32 0,000 0,14295589 0,17341695 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,14295589 0,17332553 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,14295589 0,17323421 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,14295589 0,17314299 ! meiosis I GO:0007127 52 32 0,000 0,14295589 0,17305186 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,14295589 0,17296083 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,14295589 0,17286989 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,14295589 0,17277905 ! peripheral nervous system development GO:0007422 53 32 0,000 0,14295589 0,17268831 ! regulation of protein stability GO:0031647 48 32 0,000 0,14295589 0,17259766 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,14295589 0,1725071 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,14295589 0,17241664 ! cytokine production GO:0001816 44 32 0,000 0,14295589 0,17232628 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,14295589 0,17223601 ! vesicle localization GO:0051648 47 32 0,000 0,14295589 0,17214583 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,14708149 0,17702115 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,14708149 0,17692857 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,14708149 0,17683608 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,14708149 0,17674369 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,14708149 0,17665139 ! sister chromatid segregation GO:0000819 46 33 0,000 0,14708149 0,1765592 ! ear morphogenesis GO:0042471 42 33 0,000 0,14708149 0,17646709 ! actomyosin structure organization GO:0031032 43 33 0,000 0,14708149 0,17637509 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,14708149 0,17628318 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,14708149 0,17619136 ! nucleus organization GO:0006997 49 33 0,000 0,14708149 0,17609964 ! female gonad development GO:0008585 49 33 0,000 0,14708149 0,17600802 ! positive regulation of cell development GO:0010720 54 33 0,000 0,14708149 0,17591649 ! lipid homeostasis GO:0055088 55 33 0,000 0,14708149 0,17582506 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,14708149 0,17573372 ! regulation of proteolysis GO:0030162 50 33 0,000 0,14708149 0,17564248 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,14708149 0,17555133 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,14708149 0,17546028 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,14708149 0,17536932 ! cytokinesis GO:0000910 52 33 0,000 0,14708149 0,17527845 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,14708149 0,17518768 ! mRNA catabolic process GO:0006402 48 34 0,000 0,15118746 0,17998507 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,15118746 0,17989196 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,15118746 0,17979895 ! feeding behavior GO:0007631 45 34 0,000 0,15118746 0,17970603 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,15118746 0,1796132 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,15118746 0,17952047 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,15118746 0,17942784 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,15118746 0,17933531 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,15118746 0,17924287 ! neuron migration GO:0001764 46 34 0,000 0,15118746 0,17915052 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,15118746 0,17905827 ! female gamete generation GO:0007292 43 34 0,000 0,15118746 0,17896611 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,15118746 0,17887405 ! polyol metabolic process GO:0019751 44 34 0,000 0,15118746 0,17878209 ! aerobic respiration GO:0009060 47 34 0,000 0,15118746 0,17869022 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,15118746 0,17859844 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,15118746 0,17850676 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,1552739 0,18323755 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,1552739 0,18314358 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,1552739 0,18304971 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,1552739 0,18295593 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,1552739 0,18286225 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,1552739 0,18276867 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,1552739 0,18267518 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,1552739 0,18258179 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,1552739 0,18248849 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,1552739 0,18239529 ! glycogen metabolic process GO:0005977 48 35 0,000 0,1552739 0,18230218 ! pigment metabolic process GO:0042440 61 35 0,000 0,1552739 0,18220917 ! protein homooligomerization GO:0051260 52 35 0,000 0,1552739 0,18211626 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,15934091 0,18679107 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,15934091 0,18669592 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,15934091 0,18660086 ! organic ether metabolic process GO:0018904 46 36 0,000 0,15934091 0,1865059 ! neural tube development GO:0021915 50 36 0,000 0,15934091 0,18641103 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,15934091 0,18631626 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,15934091 0,18622159 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,15934091 0,18612701 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,15934091 0,18603253 ! glucan metabolic process GO:0044042 49 36 0,000 0,15934091 0,18593815 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,16338856 0,19056475 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,16338856 0,19046816 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,16338856 0,19037168 ! learning GO:0007612 67 37 0,000 0,16338856 0,19027528 ! ion transmembrane transport GO:0034220 56 37 0,000 0,16338856 0,19017899 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,16338856 0,1900828 ! regulation of protein secretion GO:0050708 51 37 0,000 0,16338856 0,1899867 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,16338856 0,1898907 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,16741696 0,19447424 ! gliogenesis GO:0042063 71 38 0,000 0,16741696 0,19437607 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,16741696 0,194278 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,16741696 0,19418003 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,16741696 0,19408216 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,16741696 0,19398438 ! phagocytosis GO:0006909 60 38 0,000 0,16741696 0,19388671 ! maintenance of location in cell GO:0051651 69 38 0,000 0,16741696 0,19378913 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,17142618 0,19833009 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,17142618 0,19823038 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,17142618 0,19813076 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,17142618 0,19803125 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,17142618 0,19793184 ! male sex differentiation GO:0046661 53 39 0,000 0,17142618 0,19783252 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,17142618 0,19773331 ! chromatin remodeling GO:0006338 68 39 0,000 0,17142618 0,1976342 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,17142618 0,19753518 ! developmental growth GO:0048589 62 39 0,000 0,17142618 0,19743627 ! cell growth GO:0016049 61 39 0,000 0,17142618 0,19733745 ! synapse organization GO:0050808 55 39 0,000 0,17142618 0,19723873 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,17541633 0,20172878 ! response to calcium ion GO:0051592 58 40 0,000 0,17541633 0,20162797 ! regulation of tube size GO:0035150 60 40 0,000 0,17541633 0,20152726 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,17541633 0,20142664 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,17541633 0,20132613 ! peptide metabolic process GO:0006518 56 40 0,000 0,17541633 0,20122572 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,17541633 0,20112541 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,17541633 0,2010252 ! double-strand break repair GO:0006302 67 40 0,000 0,17541633 0,20092508 ! B cell differentiation GO:0030183 62 40 0,000 0,17541633 0,20082507 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,17541633 0,20072516 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,17541633 0,20062534 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,1793875 0,20506523 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,1793875 0,20496336 ! endosome transport GO:0016197 71 41 0,000 0,1793875 0,20486159 ! striated muscle contraction GO:0006941 62 41 0,000 0,1793875 0,20475992 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,1793875 0,20465836 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,1793875 0,20455689 ! biopolymer methylation GO:0043414 62 41 0,000 0,1793875 0,20445552 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,1793875 0,20435426 ! mitochondrial transport GO:0006839 60 42 0,000 0,18333976 0,20875319 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,18333976 0,2086499 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,18333976 0,20854671 ! cellular component disassembly GO:0022411 64 42 0,000 0,18333976 0,20844362 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,18333976 0,20834064 ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,18333976 0,20823775 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,18333976 0,20813497 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,18333976 0,20803229 ! excretion GO:0007588 63 42 0,000 0,18333976 0,20792971 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,18333976 0,20782723 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,18333976 0,20772485 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,18333976 0,20762258 ! neuromuscular process GO:0050905 79 43 0,000 0,18727322 0,21197264 ! activation of caspase activity GO:0006919 65 43 0,000 0,18727322 0,21186837 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,18727322 0,21176421 ! tRNA processing GO:0008033 49 43 0,000 0,18727322 0,21166015 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,18727322 0,21155619 ! vesicle organization GO:0016050 79 43 0,000 0,18727322 0,21145233 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,18727322 0,21134858 ! methylation GO:0032259 64 43 0,000 0,18727322 0,21124492 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,19118795 0,21555504 ! glycolysis GO:0006096 53 44 0,000 0,19118795 0,21544943 ! regulation of action potential GO:0001508 71 44 0,000 0,19118795 0,21534392 ! regulation of ion transport GO:0043269 57 44 0,000 0,19118795 0,21523852 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,19118795 0,21513321 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,19118795 0,21502801 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,19118795 0,21492292 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,19118795 0,21481792 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,19508405 0,21908854 ! RNA catabolic process GO:0006401 64 45 0,000 0,19508405 0,21898161 ! regulation of translational initiation GO:0006446 64 45 0,000 0,19508405 0,21887479 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,19508405 0,21876807 ! cell recognition GO:0008037 58 45 0,000 0,19508405 0,21866146 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,19896161 0,22289903 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,19896161 0,22279051 ! cell redox homeostasis GO:0045454 63 46 0,000 0,19896161 0,22268209 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,19896161 0,22257378 ! regulation of ossification GO:0030278 71 46 0,000 0,19896161 0,22246558 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,19896161 0,22235748 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,20282071 0,22656028 ! viral infectious cycle GO:0019058 71 47 0,000 0,20282071 0,2264503 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,20282071 0,22634043 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,20282071 0,22623066 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,20282071 0,226121 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,20282071 0,22601145 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,20282071 0,225902 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,20282071 0,22579265 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,20282071 0,22568342 ! chloride transport GO:0006821 67 48 0,000 0,20666143 0,22984589 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,20666143 0,2297348 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,20666143 0,22962381 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,20666143 0,22951294 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,20666143 0,22940217 ! gastrulation GO:0007369 73 48 0,000 0,20666143 0,22929151 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,20666143 0,22918095 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,20666143 0,2290705 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,20666143 0,22896016 ! regulation of endocytosis GO:0030100 63 48 0,000 0,20666143 0,22884992 ! nuclear export GO:0051168 69 48 0,000 0,20666143 0,2287398 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,20666143 0,22862977 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,21048387 0,23274659 ! sensory perception of smell GO:0007608 61 49 0,000 0,21048387 0,23263475 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,21048387 0,23252301 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,21048387 0,23241138 ! RNA elongation GO:0006354 62 49 0,000 0,21048387 0,23229986 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,21048387 0,23218845 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,21048387 0,23207714 ! germ cell development GO:0007281 68 49 0,000 0,21048387 0,23196594 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,21048387 0,23185484 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,21048387 0,23174385 ! maintenance of location GO:0051235 84 49 0,000 0,21048387 0,23163297 ! regulation of actin filament length GO:0030832 72 50 0,000 0,21428812 0,23570668 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,21428812 0,23559401 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,21428812 0,23548145 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,21428812 0,23536899 ! proton transport GO:0015992 75 50 0,000 0,21428812 0,23525664 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,21428812 0,2351444 ! positive regulation of secretion GO:0051047 71 51 0,000 0,21807424 0,23918491 ! hydrogen transport GO:0006818 77 51 0,000 0,21807424 0,23907091 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,21807424 0,23895701 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,21807424 0,23884322 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,21807424 0,23872954 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,21807424 0,23861597 ! adult behavior GO:0030534 80 51 0,000 0,21807424 0,2385025 ! transition metal ion transport GO:0000041 74 52 0,000 0,22184235 0,24250827 ! regulation of cellular component size GO:0032535 74 52 0,000 0,22184235 0,24239306 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,22184235 0,24227796 ! aging GO:0007568 79 52 0,000 0,22184235 0,24216298 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,22184235 0,2420481 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,22184235 0,24193333 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,2255925 0,24590652 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,2255925 0,24579003 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,2255925 0,24567365 ! kidney development GO:0001822 90 53 0,000 0,2255925 0,24555739 ! single fertilization GO:0007338 59 53 0,000 0,2255925 0,24544123 ! amino acid transport GO:0006865 84 54 0,000 0,2293248 0,24938394 ! regulation of mitosis GO:0007088 84 54 0,000 0,2293248 0,24926609 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,2293248 0,24914834 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,2293248 0,24903071 ! DNA catabolic process GO:0006308 67 54 0,000 0,2293248 0,24891319 ! detection of external stimulus GO:0009581 66 54 0,000 0,2293248 0,24879577 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,2293248 0,24867847 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,2293248 0,24856128 ! exocytosis GO:0006887 74 55 0,000 0,23303932 0,25246842 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,23303932 0,25234955 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,23303932 0,2522308 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,23673616 0,25611155 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,24041538 0,25996962 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,24041538 0,25984745 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,24041538 0,2597254 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,24041538 0,25960346 ! camera-type eye development GO:0043010 88 57 0,000 0,24041538 0,25948164 ! secondary metabolic process GO:0019748 84 57 0,000 0,24041538 0,25935993 ! gonad development GO:0008406 79 57 0,000 0,24041538 0,25923834 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,24407708 0,26306339 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,24407708 0,26294018 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,24407708 0,26281708 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,24772134 0,26661632 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,24772134 0,26649162 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,25134823 0,27026692 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,25134823 0,27014062 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,25134823 0,27001445 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,25134823 0,26988839 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,25134823 0,26976245 ! fertilization GO:0009566 68 60 0,000 0,25134823 0,26963663 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,25495785 0,27338138 ! meiosis GO:0007126 96 61 0,000 0,25495785 0,27325399 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,25495785 0,27312671 ! urogenital system development GO:0001655 101 61 0,000 0,25495785 0,27299956 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,25495785 0,27287252 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,25495785 0,27274561 ! extracellular matrix organization GO:0030198 103 61 0,000 0,25495785 0,27261881 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,25495785 0,27249213 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,25495785 0,27236556 ! amine catabolic process GO:0009310 90 62 0,000 0,25855027 0,27607503 ! neurotransmitter transport GO:0006836 81 62 0,000 0,25855027 0,27594692 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,25855027 0,27581893 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,25855027 0,27569106 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,25855027 0,27556331 ! meiotic cell cycle GO:0051321 97 62 0,000 0,25855027 0,27543567 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,26212557 0,27911519 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,26212557 0,27898603 ! regulation of lipase activity GO:0060191 109 63 0,000 0,26212557 0,27885699 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,26568384 0,28251171 ! appendage morphogenesis GO:0035107 93 64 0,000 0,26568384 0,28238116 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,26568384 0,28225073 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,26568384 0,28212042 ! hexose catabolic process GO:0019320 82 64 0,000 0,26568384 0,28199023 ! reproductive structure development GO:0048608 90 65 0,000 0,26922515 0,28561709 ! regulation of caspase activity GO:0043281 97 65 0,000 0,26922515 0,28548541 ! appendage development GO:0048736 94 65 0,000 0,26922515 0,28535385 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,26922515 0,28522241 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,26922515 0,28509109 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,26922515 0,28495989 ! defense response to bacterium GO:0042742 73 65 0,000 0,26922515 0,28482882 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,26922515 0,28469786 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,26922515 0,28456702 ! activation of immune response GO:0002253 83 65 0,000 0,26922515 0,28443631 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,27274959 0,28802757 ! antigen processing and presentation GO:0019882 96 66 0,000 0,27274959 0,28789539 ! axon guidance GO:0007411 99 66 0,000 0,27274959 0,28776332 ! regulation of immune effector process GO:0002697 101 66 0,000 0,27274959 0,28763138 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,27625722 0,29119689 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,27625722 0,2910635 ! acute inflammatory response GO:0002526 92 68 0,000 0,27974815 0,29460656 ! learning or memory GO:0007611 123 68 0,000 0,27974815 0,29447173 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,27974815 0,29433702 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,27974815 0,29420244 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,27974815 0,29406798 ! rhythmic process GO:0048511 105 68 0,000 0,27974815 0,29393364 ! inorganic anion transport GO:0015698 93 68 0,000 0,27974815 0,29379942 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,28322243 0,29731245 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,28322243 0,29717682 ! response to drug GO:0042493 108 69 0,000 0,28322243 0,29704131 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,28322243 0,29690592 ! response to metal ion GO:0010038 103 70 0,000 0,28668015 0,30039378 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,28668015 0,30025699 ! humoral immune response GO:0006959 86 70 0,000 0,28668015 0,30012032 ! amine transport GO:0015837 101 70 0,000 0,28668015 0,29998378 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,28668015 0,29984736 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,29012139 0,30330873 ! muscle cell differentiation GO:0042692 104 71 0,000 0,29012139 0,30317092 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,29012139 0,30303324 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,29012139 0,30289569 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,29012139 0,30275826 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,29012139 0,30262095 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,29012139 0,30248377 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,29354623 0,30591587 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,29354623 0,30577732 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,29354623 0,30563889 ! regulation of blood pressure GO:0008217 107 73 0,000 0,29695473 0,30904791 ! tube morphogenesis GO:0035239 118 73 0,000 0,29695473 0,30890813 ! mitochondrion organization GO:0007005 104 73 0,000 0,29695473 0,30876848 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,29695473 0,30862896 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,29695473 0,30848956 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,30034699 0,31187272 ! digestion GO:0007586 97 74 0,000 0,30034699 0,31173198 ! protein import into nucleus GO:0006606 118 74 0,000 0,30034699 0,31159137 ! response to inorganic substance GO:0010035 115 75 0,000 0,30372307 0,31495179 ! regulation of ligase activity GO:0051340 114 75 0,000 0,30372307 0,31480985 ! nuclear import GO:0051170 121 75 0,000 0,30372307 0,31466805 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,30372307 0,31452637 ! amine biosynthetic process GO:0009309 97 76 0,000 0,30708306 0,31786275 ! response to unfolded protein GO:0006986 99 76 0,000 0,30708306 0,31771976 ! regulation of protein transport GO:0051223 114 76 0,000 0,30708306 0,3175769 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,31042702 0,32089085 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,31042702 0,3207467 ! sex differentiation GO:0007548 105 77 0,000 0,31042702 0,32060267 ! protein ubiquitination GO:0016567 125 77 0,000 0,31042702 0,32045877 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,31042702 0,32031501 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,31042702 0,32017137 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,31042702 0,32002786 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,31375504 0,32331388 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,31375504 0,32316909 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,31706718 0,32643443 ! cellular respiration GO:0045333 107 79 0,000 0,31706718 0,32628838 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,31706718 0,32614245 ! T cell activation GO:0042110 134 79 0,000 0,31706718 0,32599666 ! regulation of lyase activity GO:0051339 133 79 0,000 0,31706718 0,32585099 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,31706718 0,32570546 ! chromatin assembly GO:0031497 102 80 0,000 0,32036353 0,3289447 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,32036353 0,32879791 ! protein localization in nucleus GO:0034504 133 80 0,000 0,32036353 0,32865126 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,32364416 0,33186873 ! mRNA transport GO:0051028 121 81 0,000 0,32364416 0,33172084 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,32364416 0,33157308 ! response to protein stimulus GO:0051789 111 81 0,000 0,32364416 0,33142545 ! regulation of neurological system process GO:0031644 122 81 0,000 0,32364416 0,33127795 ! vitamin metabolic process GO:0006766 103 81 0,000 0,32364416 0,33113059 ! detection of stimulus GO:0051606 108 82 0,000 0,32690914 0,33432237 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,33015854 0,3374954 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,33015854 0,33734547 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,33015854 0,33719567 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,33339244 0,34034737 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,33339244 0,34019637 ! sterol metabolic process GO:0016125 120 84 0,000 0,33339244 0,34004551 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,33661092 0,34317603 ! rRNA metabolic process GO:0016072 107 85 0,000 0,33661092 0,34302398 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,33661092 0,34287206 ! regulation of protein localization GO:0032880 132 85 0,000 0,33661092 0,34272028 ! regulation of membrane potential GO:0042391 128 85 0,000 0,33661092 0,34256863 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,33981404 0,34567549 ! nucleosome organization GO:0034728 114 87 0,000 0,34300188 0,34876407 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,34300188 0,34860995 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,34300188 0,34845597 ! female pregnancy GO:0007565 130 87 0,000 0,34300188 0,34830213 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,34300188 0,34814842 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,3461745 0,35121366 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,3461745 0,3510588 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,3461745 0,35090408 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,3461745 0,3507495 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,34933199 0,35379286 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,34933199 0,35363714 ! regulation of T cell activation GO:0050863 128 89 0,000 0,34933199 0,35348156 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,35247441 0,35650446 ! hormone metabolic process GO:0042445 121 90 0,000 0,35247441 0,35634776 ! RNA localization GO:0006403 135 91 0,000 0,35560184 0,35935159 ! ATP metabolic process GO:0046034 137 91 0,000 0,35560184 0,35919377 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,35871433 0,36217865 ! positive regulation of immune response GO:0050778 121 92 0,000 0,35871433 0,36201973 ! DNA recombination GO:0006310 146 92 0,000 0,35871433 0,36186095 ! sulfur metabolic process GO:0006790 118 92 0,000 0,35871433 0,36170231 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,36181197 0,36466588 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,36181197 0,36450615 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,36181197 0,36434656 ! electron transport chain GO:0022900 123 94 0,000 0,36489483 0,3672902 ! carboxylic acid transport GO:0046942 147 95 0,000 0,36796297 0,37021646 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,37101647 0,37312544 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,37101647 0,37296236 ! protein maturation GO:0051604 129 96 0,000 0,37101647 0,37279942 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,37405538 0,37568881 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,37405538 0,37552483 ! calcium ion transport GO:0006816 167 99 0,000 0,38008976 0,38141643 ! extracellular structure organization GO:0043062 156 99 0,000 0,38008976 0,38125009 ! protein import GO:0017038 156 99 0,000 0,38008976 0,38108389 ! regulation of translation GO:0006417 151 100 0,000 0,38308536 0,38391997 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,38308536 0,38375276 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,38308536 0,38358569 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,38308536 0,38341877 ! divalent metal ion transport GO:0070838 171 100 0,000 0,38308536 0,38325199 ! protein localization in organelle GO:0033365 161 100 0,000 0,38308536 0,38308536