pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1152-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of positive chemotaxis GO:0050930 15 9 3,000 2,875E-08 6,917E-05 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 5,447E-08 6,553E-05 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 1,119E-07 8,976E-05 GO:0050927|positive regulation of positive chemotaxis, ! cellular response to insulin stimulus GO:0032869 82 37 4,000 3,486E-07 2,097E-04 ! filopodium assembly GO:0046847 32 16 3,000 4,065E-07 1,956E-04 ! microspike assembly GO:0030035 36 17 3,000 5,299E-07 2,125E-04 ! positive regulation of glycolysis GO:0045821 14 5 2,000 5,98E-07 2,055E-04 ! response to insulin stimulus GO:0032868 95 46 4,000 1,066E-06 3,205E-04 ! nuclear migration GO:0007097 12 6 2,000 1,193E-06 3,188E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 1,193E-06 2,869E-04 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of locomotion GO:0040017 39 21 3,000 1,316E-06 2,879E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 40 22 3,000 1,604E-06 3,216E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 2,081E-06 3,851E-04 ! macrophage differentiation GO:0030225 11 7 2,000 2,081E-06 3,576E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 2,081E-06 3,338E-04 ! regulation of behavior GO:0050795 43 24 3,000 2,316E-06 3,483E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 2,316E-06 3,278E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 3,239E-06 4,329E-04 GO:0045936|negative regulation of phosphate metabolic process, ! establishment of nucleus localization GO:0040023 16 8 2,000 3,32E-06 4,204E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 3,32E-06 3,994E-04 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 4,412E-06 5,054E-04 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 4,966E-06 5,43E-04 ! regulation of glycolysis GO:0006110 21 9 2,000 4,966E-06 5,194E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 7,073E-06 7,091E-04 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 2,000 7,073E-06 6,807E-04 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 7,073E-06 6,545E-04 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 9,698E-06 8,642E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 9,698E-06 8,333E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 9,698E-06 8,046E-04 GO:0010829|negative regulation of glucose transport, ! nucleus localization GO:0051647 19 11 2,000 9,698E-06 7,777E-04 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 1,289E-05 1,001E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 1,289E-05 9,694E-04 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 2,000 1,671E-05 1,218E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cellular response to hormone stimulus GO:0032870 167 82 4,000 1,894E-05 1,34E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 2,121E-05 1,458E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 2,538E-05 1,696E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 2,643E-05 1,719E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 3,046E-05 1,929E-03 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 3,244E-05 2,001E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 3,928E-05 2,363E-03 ! response to retinoic acid GO:0032526 26 18 2,000 4,7E-05 2,758E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 4,7E-05 2,692E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 5,418E-05 3,031E-03 ! cartilage development GO:0051216 90 52 3,000 5,418E-05 2,962E-03 ! response to vitamin A GO:0033189 27 19 2,000 5,565E-05 2,975E-03 ! response to vitamin GO:0033273 31 20 2,000 6,528E-05 3,415E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 6,528E-05 3,342E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of glucose import GO:0046324 29 20 2,000 6,528E-05 3,272E-03 GO:0010827|regulation of glucose transport, ! inactivation of MAPK activity GO:0000188 39 21 2,000 7,594E-05 3,729E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 7,594E-05 3,654E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 7,785E-05 3,673E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 1,005E-04 4,652E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 1,146E-04 5,201E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 1,226E-04 5,462E-03 ! vasculogenesis GO:0001570 46 25 2,000 1,298E-04 5,679E-03 ! interaction with host GO:0051701 62 25 2,000 1,298E-04 5,578E-03 ! cell projection assembly GO:0030031 120 66 3,000 1,382E-04 5,834E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 1,463E-04 6,07E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 1,463E-04 5,968E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 1,465E-04 5,876E-03 ! lung development GO:0030324 144 67 3,000 1,465E-04 5,78E-03 ! neuron fate determination GO:0048664 7 5 1,000 1,536E-04 5,961E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 1,536E-04 5,867E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,536E-04 5,775E-03 ! parathyroid gland development GO:0060017 13 5 1,000 1,536E-04 5,686E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,536E-04 5,6E-03 ! mRNA transcription GO:0009299 9 5 1,000 1,536E-04 5,516E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 1,536E-04 5,435E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,536E-04 5,357E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 1,536E-04 5,28E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 1,552E-04 5,26E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 1,642E-04 5,485E-03 ! respiratory tube development GO:0030323 150 70 3,000 1,737E-04 5,725E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 1,833E-04 5,96E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 1,833E-04 5,881E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 1,937E-04 6,133E-03 ! respiratory system development GO:0060541 153 72 3,000 1,937E-04 6,053E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 2,039E-04 6,289E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 2,298E-04 7E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 2,298E-04 6,912E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 2,298E-04 6,827E-03 ! male sex determination GO:0030238 15 6 1,000 2,298E-04 6,744E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 2,744E-04 7,954E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 2,744E-04 7,859E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 3,009E-04 8,519E-03 GO:0060326|cell chemotaxis, ! response to hypoxia GO:0001666 171 81 3,000 3,048E-04 8,528E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 3,209E-04 8,875E-03 ! mRNA stabilization GO:0048255 18 7 1,000 3,209E-04 8,775E-03 GO:0043489|RNA stabilization, ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 3,209E-04 8,676E-03 ! oxygen homeostasis GO:0032364 12 7 1,000 3,209E-04 8,58E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 3,209E-04 8,485E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 3,291E-04 8,607E-03 ! response to oxygen levels GO:0070482 176 83 3,000 3,347E-04 8,658E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 4,237E-04 0,0108445 ! tissue remodeling GO:0048771 76 37 2,000 4,237E-04 0,01073034 ! T-helper 1 type immune response GO:0042088 12 8 1,000 4,268E-04 0,01069669 ! hemoglobin metabolic process GO:0020027 13 8 1,000 4,268E-04 0,01058642 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 4,268E-04 0,01047839 ! regulation of vascular permeability GO:0043114 12 8 1,000 4,268E-04 0,01037255 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 4,268E-04 0,01026883 ! carbohydrate homeostasis GO:0033500 53 38 2,000 4,587E-04 0,01092653 GO:0042593|glucose homeostasis, ! regulation of developmental growth GO:0048638 15 9 1,000 5,473E-04 0,01291043 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 5,473E-04 0,01278509 ! regulation of Notch signaling pathway GO:0008593 22 9 1,000 5,473E-04 0,01266216 ! protein heterooligomerization GO:0051291 16 9 1,000 5,473E-04 0,01254156 ! gas homeostasis GO:0033483 16 9 1,000 5,473E-04 0,01242325 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 5,473E-04 0,01230714 ! response to virus GO:0009615 160 98 3,000 6,286E-04 0,014004 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 6,824E-04 0,01506262 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 6,824E-04 0,01492569 ! lung alveolus development GO:0048286 26 10 1,000 6,824E-04 0,01479122 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 6,824E-04 0,01465916 ! regulation of bone resorption GO:0045124 25 10 1,000 6,824E-04 0,01452943 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 6,824E-04 0,01440198 ! JAK-STAT cascade GO:0007259 71 44 2,000 7,078E-04 0,01480803 ! leukocyte migration GO:0050900 68 45 2,000 7,562E-04 0,01568385 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 8,066E-04 0,01658695 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 8,066E-04 0,01644638 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 8,319E-04 0,01681925 ! blood vessel remodeling GO:0001974 29 11 1,000 8,319E-04 0,01667909 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 8,319E-04 0,01654125 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 8,319E-04 0,01640566 ! regulation of leukocyte migration GO:0002685 26 11 1,000 8,319E-04 0,01627229 ! thymus development GO:0048538 27 11 1,000 8,319E-04 0,01614106 ! regulation of embryonic development GO:0045995 27 11 1,000 8,319E-04 0,01601193 ! positive regulation of defense response GO:0031349 76 47 2,000 8,591E-04 0,01640513 ! regulation of inflammatory response GO:0050727 75 48 2,000 9,138E-04 0,01731124 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 9,706E-04 0,01824372 ! endocrine system development GO:0035270 104 49 2,000 9,706E-04 0,01810229 ! virus-host interaction GO:0019048 29 12 1,000 9,957E-04 0,01842758 ! regulation of B cell proliferation GO:0030888 20 12 1,000 9,957E-04 0,01828691 ! focal adhesion formation GO:0048041 35 12 1,000 9,957E-04 0,01814837 ! entry into host cell GO:0030260 32 12 1,000 9,957E-04 0,01801192 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 9,957E-04 0,0178775 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 9,957E-04 0,01774508 ! peptidyl-lysine modification GO:0018205 21 12 1,000 9,957E-04 0,0176146 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 9,957E-04 0,01748602 ! regulation of cell projection organization GO:0031344 121 50 2,000 1,03E-03 0,01795021 ! regulation of muscle contraction GO:0006937 81 52 2,000 1,154E-03 0,01997917 ! membrane fusion GO:0006944 110 52 2,000 1,154E-03 0,01983646 ! regulation of chemokine production GO:0032642 18 13 1,000 1,174E-03 0,0200272 ! plasma membrane organization GO:0007009 24 13 1,000 1,174E-03 0,01988617 ! Golgi organization GO:0007030 24 13 1,000 1,174E-03 0,0197471 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,174E-03 0,01960997 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,174E-03 0,01947473 ! regulation of mRNA stability GO:0043488 31 13 1,000 1,174E-03 0,01934134 ! embryonic placenta development GO:0001892 23 13 1,000 1,174E-03 0,01920976 ! heart morphogenesis GO:0003007 97 55 2,000 1,358E-03 0,02208422 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,366E-03 0,02205349 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 1,366E-03 0,02190647 ! regulation of RNA stability GO:0043487 32 14 1,000 1,366E-03 0,02176139 ! regulation of DNA replication GO:0006275 101 56 2,000 1,431E-03 0,02265515 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 1,506E-03 0,02368945 ! ER-associated protein catabolic process GO:0030433 24 15 1,000 1,572E-03 0,02455662 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,572E-03 0,02439819 ! pituitary gland development GO:0021983 29 15 1,000 1,572E-03 0,02424179 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,572E-03 0,02408738 ! muscle maintenance GO:0046716 26 15 1,000 1,572E-03 0,02393493 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 1,572E-03 0,0237844 ! establishment of organelle localization GO:0051656 109 59 2,000 1,664E-03 0,02502454 ! regulation of heart contraction GO:0008016 110 60 2,000 1,747E-03 0,02610311 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 1,747E-03 0,02594198 ! auditory receptor cell differentiation GO:0042491 32 16 1,000 1,792E-03 0,02644671 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,792E-03 0,02628545 ! regulation of protein complex assembly GO:0043254 117 61 2,000 1,832E-03 0,0267111 ! viral reproductive process GO:0022415 126 62 2,000 1,919E-03 0,02782039 ! regulation of homeostatic process GO:0032844 134 62 2,000 1,919E-03 0,0276538 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 2,01E-03 0,02878111 ! heart looping GO:0001947 30 17 1,000 2,025E-03 0,02883425 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 2,025E-03 0,02866464 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 2,025E-03 0,02849701 ! neural crest cell migration GO:0001755 37 17 1,000 2,025E-03 0,02833133 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 2,025E-03 0,02816756 ! myeloid cell differentiation GO:0030099 111 65 2,000 2,198E-03 0,03039152 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,273E-03 0,03124559 ! cell-substrate junction assembly GO:0007044 54 18 1,000 2,273E-03 0,03106805 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 2,397E-03 0,03257921 ! viral reproduction GO:0016032 134 68 2,000 2,5E-03 0,03379455 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 2,533E-03 0,03405316 ! lipid phosphorylation GO:0046834 35 19 1,000 2,533E-03 0,03386398 ! pigmentation during development GO:0048066 41 19 1,000 2,533E-03 0,03367689 ! actin filament bundle formation GO:0051017 42 19 1,000 2,533E-03 0,03349185 ! plasma membrane fusion GO:0045026 28 19 1,000 2,533E-03 0,03330883 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 2,533E-03 0,03312781 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 2,533E-03 0,03294874 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,808E-03 0,03631905 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 2,808E-03 0,03612483 ! diencephalon development GO:0021536 34 20 1,000 2,808E-03 0,03593268 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 2,808E-03 0,03574256 ! inner ear receptor cell differentiation GO:0060113 37 20 1,000 2,808E-03 0,03555444 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 2,941E-03 0,03705321 ! regulation of transcription factor activity GO:0051090 126 74 2,000 3,179E-03 0,03983577 GO:0090046|regulation of transcription regulator activity, ! organelle localization GO:0051640 136 74 2,000 3,179E-03 0,03962937 ! cell-matrix adhesion GO:0007160 163 75 2,000 3,302E-03 0,04095061 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 3,396E-03 0,04190166 ! mechanoreceptor differentiation GO:0042490 40 22 1,000 3,396E-03 0,04168787 ! positive regulation of B cell activation GO:0050871 38 22 1,000 3,396E-03 0,04147626 ! regulation of catabolic process GO:0009894 161 76 2,000 3,428E-03 0,04165304 ! positive regulation of DNA replication GO:0045740 43 23 1,000 3,71E-03 0,04485406 ! sex determination GO:0007530 47 23 1,000 3,71E-03 0,04462979 ! platelet activation GO:0030168 37 23 1,000 3,71E-03 0,04440775 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 3,823E-03 0,04553496 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,037E-03 0,04784408 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 4,037E-03 0,04760955 ! protein tetramerization GO:0051262 52 24 1,000 4,037E-03 0,04737731 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 4,101E-03 0,04790038 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 2,000 4,101E-03 0,04766897 ! response to nutrient GO:0007584 125 82 2,000 4,245E-03 0,04910096 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 4,376E-03 0,05038152 ! neural crest cell development GO:0014032 54 25 1,000 4,376E-03 0,05014161 GO:0014033|neural crest cell differentiation, ! somitogenesis GO:0001756 43 25 1,000 4,376E-03 0,04990397 ! liver development GO:0001889 53 25 1,000 4,376E-03 0,04966858 ! negative regulation of transport GO:0051051 153 84 2,000 4,541E-03 0,0512953 ! negative regulation of growth GO:0045926 155 84 2,000 4,541E-03 0,0510556 ! initiation of viral infection GO:0019059 57 26 1,000 4,729E-03 0,05292035 ! cellular response to oxidative stress GO:0034599 39 26 1,000 4,729E-03 0,05267535 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 5,094E-03 0,05648161 ! neuron fate commitment GO:0048663 48 27 1,000 5,094E-03 0,05622252 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 5,094E-03 0,0559658 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 5,094E-03 0,05571141 ! protein amino acid acylation GO:0043543 55 27 1,000 5,094E-03 0,05545932 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 5,094E-03 0,0552095 ! positive regulation of protein modification process GO:0031401 136 88 2,000 5,171E-03 0,05578625 ! regulation of DNA binding GO:0051101 155 88 2,000 5,171E-03 0,05553721 ! gland development GO:0048732 206 88 2,000 5,171E-03 0,05529037 ! regulation of defense response GO:0031347 149 92 2,000 5,85E-03 0,06227938 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 5,862E-03 0,06213333 ! cell fate determination GO:0001709 60 29 1,000 5,862E-03 0,06186082 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 5,862E-03 0,06159068 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 6,028E-03 0,06305626 ! cell junction assembly GO:0034329 78 30 1,000 6,265E-03 0,06525062 ! regulation of B cell activation GO:0050864 50 30 1,000 6,265E-03 0,06496937 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 6,393E-03 0,06601594 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 6,393E-03 0,06573382 ! leukocyte differentiation GO:0002521 202 96 2,000 6,581E-03 0,06737344 ! collagen metabolic process GO:0032963 45 31 1,000 6,68E-03 0,06809756 ! iron ion homeostasis GO:0055072 54 31 1,000 6,68E-03 0,06781023 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 6,68E-03 0,06752531 GO:0043433|negative regulation of transcription factor activity, ! regulation of DNA metabolic process GO:0051052 178 97 2,000 6,771E-03 0,06816578 ! interphase GO:0051325 213 98 2,000 6,965E-03 0,06982638 ! regulation of ARF GTPase activity GO:0032312 65 32 1,000 7,107E-03 0,07094778 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 7,546E-03 0,07501993 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 7,997E-03 0,07917699 ! placenta development GO:0001890 53 34 1,000 7,997E-03 0,07885249 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 8,46E-03 0,08307644 ! cell junction organization GO:0034330 86 36 1,000 8,934E-03 0,08738108 ! embryonic organ development GO:0048568 57 36 1,000 8,934E-03 0,08702731 ! negative regulation of DNA binding GO:0043392 68 37 1,000 9,421E-03 0,09139445 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 9,918E-03 0,09583826 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 9,918E-03 0,0954549 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! segmentation GO:0035282 67 39 1,000 0,01042777 0,09995705 ! negative regulation of binding GO:0051100 72 40 1,000 0,01094849 0,10453202 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,01094849 0,10411885 ! mesenchymal cell development GO:0014031 87 40 1,000 0,01094849 0,10370893 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01202366 0,11344673 GO:0090047|positive regulation of transcription regulator activity, ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,01202366 0,11300358 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,01257791 0,11775274 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 0,01257791 0,11729633 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,01257791 0,11684345 ! glucose transport GO:0015758 65 43 1,000 0,01257791 0,11639405 ! hexose transport GO:0008645 67 44 1,000 0,01314316 0,12115874 GO:0015749|monosaccharide transport, ! negative regulation of cell migration GO:0030336 115 46 1,000 0,01430624 0,13137711 ! pigmentation GO:0043473 100 46 1,000 0,01430624 0,13087758 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01490388 0,13582859 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01490388 0,13531603 ! JNK cascade GO:0007254 91 47 1,000 0,01490388 0,13480732 ! Notch signaling pathway GO:0007219 96 48 1,000 0,01551215 0,13978365 ! regulation of ARF protein signal transduction GO:0032012 102 48 1,000 0,01551215 0,13926207 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,01551215 0,13874437 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,01613094 0,14374461 ! inner ear development GO:0048839 79 50 1,000 0,01676017 0,14880058 ! histone modification GO:0016570 91 50 1,000 0,01676017 0,14825352 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,01676017 0,14771047 ! positive regulation of binding GO:0051099 78 51 1,000 0,01739973 0,15278743 ! viral infectious cycle GO:0019058 99 51 1,000 0,01739973 0,15223184 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,01739973 0,15168028 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 0,01739973 0,15113269 ! positive regulation of growth GO:0045927 90 52 1,000 0,01804955 0,15621303 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01804955 0,15565313 ! amino acid activation GO:0043038 92 52 1,000 0,01804955 0,15509722 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cell maturation GO:0048469 100 53 1,000 0,01870953 0,16019623 ! response to UV GO:0009411 104 53 1,000 0,01870953 0,15962816 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01960207 0,1666522 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01960207 0,1660654 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01960207 0,16548271 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01960207 0,1649041 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01960207 0,16432952 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01960207 0,16375893 ! polyol transport GO:0015791 12 5 0,000 0,01960207 0,16319229 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01960207 0,16262956 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01960207 0,1620707 ! response to superoxide GO:0000303 10 5 0,000 0,01960207 0,16151566 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01960207 0,16096441 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01960207 0,16041691 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01960207 0,15987313 ! female meiosis GO:0007143 7 5 0,000 0,01960207 0,15933301 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01960207 0,15879654 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01960207 0,15826367 ! cobalt ion transport GO:0006824 11 5 0,000 0,01960207 0,15773436 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01960207 0,15720857 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01960207 0,15668629 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01960207 0,15616746 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01960207 0,15565205 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01960207 0,15514004 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01960207 0,15463139 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01960207 0,15412605 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01960207 0,15362401 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01960207 0,15312524 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01960207 0,15262968 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01960207 0,15213733 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01960207 0,15164814 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01960207 0,15116209 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01960207 0,15067915 ! negative chemotaxis GO:0050919 14 5 0,000 0,01960207 0,15019928 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01960207 0,14972245 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01960207 0,14924865 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01960207 0,14877783 ! behavioral response to pain GO:0048266 9 5 0,000 0,01960207 0,14830998 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01960207 0,14784505 ! Notch receptor processing GO:0007220 8 5 0,000 0,01960207 0,14738304 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01960207 0,1469239 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01960207 0,14646762 ! micturition GO:0060073 9 5 0,000 0,01960207 0,14601416 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01960207 0,1455635 ! copulation GO:0007620 9 5 0,000 0,01960207 0,14511561 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01960207 0,14467047 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01960207 0,14422805 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01960207 0,14378833 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01960207 0,14335128 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01960207 0,14291689 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01960207 0,14248511 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01960207 0,14205594 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01960207 0,14162935 ! grooming behavior GO:0007625 6 5 0,000 0,01960207 0,14120531 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01960207 0,1407838 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01960207 0,1403648 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01960207 0,13994829 ! response to protozoan GO:0001562 10 5 0,000 0,01960207 0,13953424 ! lymph vessel development GO:0001945 10 5 0,000 0,01960207 0,13912263 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01960207 0,13871345 ! endochondral ossification GO:0001958 16 5 0,000 0,01960207 0,13830666 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01960207 0,13790226 ! anagen GO:0042640 6 5 0,000 0,01960207 0,13750021 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01960207 0,1371005 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01960207 0,13670311 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01960207 0,13630801 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01960207 0,13591519 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01960207 0,13552463 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01960207 0,13513631 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01960207 0,13475021 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01960207 0,1343663 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01960207 0,13398458 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01960207 0,13360502 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01960207 0,13322761 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01960207 0,13285232 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01960207 0,13247914 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01960207 0,13210805 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01960207 0,13173903 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01960207 0,13137207 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01960207 0,13100715 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01960207 0,13064424 ! histidine catabolic process GO:0006548 6 5 0,000 0,01960207 0,13028335 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01960207 0,12992444 ! microvillus organization GO:0032528 7 5 0,000 0,01960207 0,12956751 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01960207 0,12921253 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01960207 0,12885949 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01960207 0,12850837 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01960207 0,12815916 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01960207 0,12781185 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01960207 0,12746641 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01960207 0,12712284 ! polyol catabolic process GO:0046174 7 5 0,000 0,01960207 0,12678111 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01960207 0,12644121 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01960207 0,12610313 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01960207 0,12576686 ! muscle cell migration GO:0014812 8 5 0,000 0,01960207 0,12543237 ! mitochondrial fission GO:0000266 8 5 0,000 0,01960207 0,12509966 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01960207 0,12476871 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01960207 0,12443951 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01960207 0,12411203 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01960207 0,12378628 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01960207 0,12346223 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01960207 0,12313988 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01960207 0,1228192 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01960207 0,12250019 ! response to food GO:0032094 6 5 0,000 0,01960207 0,12218283 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01960207 0,12186711 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01960207 0,12155302 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01960207 0,12124055 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01960207 0,12092967 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01960207 0,12062039 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01960207 0,12031268 ! forebrain neuron development GO:0021884 13 5 0,000 0,01960207 0,12000655 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01960207 0,11970196 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01960207 0,11939892 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01960207 0,11909741 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01960207 0,11879741 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01960207 0,11849893 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01960207 0,11820194 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01960207 0,11790643 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01960207 0,1176124 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01960207 0,11731983 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01960207 0,11702872 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01960207 0,11673904 ! basic amino acid transport GO:0015802 11 5 0,000 0,01960207 0,1164508 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01960207 0,11616397 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01960207 0,11587856 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01960207 0,11559454 ! depyrimidination GO:0045008 10 5 0,000 0,01960207 0,11531191 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01960207 0,11503066 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01960207 0,11475078 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01960207 0,11447226 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01960207 0,11419509 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01960207 0,11391926 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01960207 0,11364475 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01960207 0,11337157 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01960207 0,11309969 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01960207 0,11282912 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01960207 0,11255984 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01960207 0,11229184 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01960207 0,11202511 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01960207 0,11175965 ! response to arsenic GO:0046685 10 5 0,000 0,01960207 0,11149544 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01960207 0,11123248 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01960207 0,11097076 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01960207 0,11071026 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01960207 0,11045099 ! response to cadmium ion GO:0046686 7 5 0,000 0,01960207 0,11019293 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01960207 0,10993607 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01960207 0,1096804 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01960207 0,10942592 ! decidualization GO:0046697 11 5 0,000 0,01960207 0,10917262 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01960207 0,10892049 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01960207 0,10866952 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01960207 0,10841971 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01960207 0,10817104 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01960207 0,10792351 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01960207 0,10767711 ! neural tube patterning GO:0021532 7 5 0,000 0,01960207 0,10743183 ! embryonic cleavage GO:0040016 6 5 0,000 0,01960207 0,10718766 ! peroxisome fission GO:0016559 5 5 0,000 0,01960207 0,10694461 ! histone demethylation GO:0016577 10 5 0,000 0,01960207 0,10670265 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01960207 0,10646179 ! mitotic recombination GO:0006312 9 5 0,000 0,01960207 0,10622201 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01960207 0,10598331 ! metaphase plate congression GO:0051310 7 5 0,000 0,01960207 0,10574568 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01960207 0,10550911 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01960207 0,1052736 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01960207 0,10503914 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01960207 0,10480572 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01960207 0,10457333 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01960207 0,10434197 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01960207 0,10411164 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01960207 0,10388232 ! plasminogen activation GO:0031639 5 5 0,000 0,01960207 0,10365401 ! B cell homeostasis GO:0001782 13 5 0,000 0,01960207 0,10342669 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01960207 0,10320038 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01960207 0,10297505 ! metaphase GO:0051323 8 5 0,000 0,01960207 0,1027507 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01960207 0,10252733 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01960207 0,10230493 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01960207 0,10208349 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01960207 0,10186301 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01960207 0,10164348 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01960207 0,10142489 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01960207 0,10120724 ! response to redox state GO:0051775 5 5 0,000 0,01960207 0,10099052 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01960207 0,10077473 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01960207 0,10055986 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01960207 0,1003459 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01960207 0,10013285 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01960207 0,0999207 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01960207 0,09970946 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01960207 0,0994991 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01960207 0,09928963 ! striatum development GO:0021756 9 5 0,000 0,01960207 0,09908103 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01960207 0,09887332 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01960207 0,09866647 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01960207 0,09846049 ! glial cell migration GO:0008347 11 5 0,000 0,01960207 0,09825536 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01960207 0,09805109 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01960207 0,09784766 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01960207 0,09764508 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01960207 0,09744333 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01960207 0,09724242 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01960207 0,09704233 ! neuroprotection GO:0043526 6 5 0,000 0,01960207 0,09684306 ! neural plate development GO:0001840 8 5 0,000 0,01960207 0,09664462 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01960207 0,09644698 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01960207 0,09625015 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01960207 0,09605412 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01960207 0,09585889 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01960207 0,09566445 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01960207 0,09547079 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01960207 0,09527792 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01960207 0,09508583 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01960207 0,09489451 ! spindle assembly GO:0051225 6 5 0,000 0,01960207 0,09470396 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01960207 0,09451417 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01960207 0,09432514 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01960207 0,09413687 ! drug metabolic process GO:0017144 6 5 0,000 0,01960207 0,09394935 ! stem cell division GO:0017145 11 5 0,000 0,01960207 0,09376257 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,01960207 0,09357653 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01960207 0,09339123 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01960207 0,09320666 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01960207 0,09302283 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,02005963 0,09500685 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,02144933 0,10138915 ! lipid modification GO:0030258 97 57 1,000 0,02144933 0,10119035 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,0221588 0,10433282 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,02287791 0,1075083 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02347651 0,11010622 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02347651 0,10989201 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02347651 0,10967863 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02347651 0,10946607 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02347651 0,10925434 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02347651 0,10904342 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02347651 0,10883332 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02347651 0,10862402 ! sleep GO:0030431 13 6 0,000 0,02347651 0,10841553 ! response to oxygen radical GO:0000305 11 6 0,000 0,02347651 0,10820784 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02347651 0,10800094 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02347651 0,10779483 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02347651 0,10758951 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02347651 0,10738497 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02347651 0,1071812 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02347651 0,10697821 ! forebrain regionalization GO:0021871 8 6 0,000 0,02347651 0,10677598 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02347651 0,10657451 ! male meiosis GO:0007140 7 6 0,000 0,02347651 0,10637381 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02347651 0,10617386 ! response to zinc ion GO:0010043 9 6 0,000 0,02347651 0,10597466 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02347651 0,1057762 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02347651 0,10557849 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02347651 0,10538152 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02347651 0,10518527 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02347651 0,10498976 ! malate metabolic process GO:0006108 11 6 0,000 0,02347651 0,10479498 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02347651 0,10460091 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02347651 0,10440756 ! protein refolding GO:0042026 15 6 0,000 0,02347651 0,10421493 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02347651 0,10402301 ! opsonization GO:0008228 8 6 0,000 0,02347651 0,10383179 ! mating behavior GO:0007617 7 6 0,000 0,02347651 0,10364127 ! neuron remodeling GO:0016322 15 6 0,000 0,02347651 0,10345145 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02347651 0,10326233 ! equilibrioception GO:0050957 14 6 0,000 0,02347651 0,10307389 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02347651 0,10288614 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02347651 0,10269908 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02347651 0,10251269 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02347651 0,10232698 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02347651 0,10214194 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02347651 0,10195757 ! toxin metabolic process GO:0009404 11 6 0,000 0,02347651 0,10177386 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02347651 0,10159081 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02347651 0,10140842 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02347651 0,10122669 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02347651 0,1010456 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02347651 0,10086516 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02347651 0,10068537 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02347651 0,10050621 ! thymic T cell selection GO:0045061 12 6 0,000 0,02347651 0,1003277 ! protein lipoylation GO:0009249 10 6 0,000 0,02347651 0,10014981 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02347651 0,09997255 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02347651 0,09979592 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02347651 0,09961992 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02347651 0,09944453 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02347651 0,09926976 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02347651 0,0990956 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02347651 0,09892205 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02347651 0,09874911 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02347651 0,09857678 ! hyperosmotic response GO:0006972 9 6 0,000 0,02347651 0,09840504 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02347651 0,0982339 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02347651 0,09806335 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02347651 0,0978934 ! urea metabolic process GO:0019627 7 6 0,000 0,02347651 0,09772404 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02347651 0,09755525 ! neutrophil activation GO:0042119 8 6 0,000 0,02347651 0,09738706 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02347651 0,09721944 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02347651 0,09705239 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02347651 0,09688592 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02347651 0,09672002 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02347651 0,09655469 ! neuron apoptosis GO:0051402 9 6 0,000 0,02347651 0,09638992 ! nucleoside salvage GO:0043174 9 6 0,000 0,02347651 0,09622571 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02347651 0,09606206 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02347651 0,09589897 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02347651 0,09573643 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02347651 0,09557444 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02347651 0,09541299 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02347651 0,0952521 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02347651 0,09509174 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02347651 0,09493192 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02347651 0,09477264 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02347651 0,09461389 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02347651 0,09445567 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02347651 0,09429798 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02347651 0,09414082 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02347651 0,09398418 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02347651 0,09382806 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02347651 0,09367246 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02347651 0,09351737 ! neural nucleus development GO:0048857 14 6 0,000 0,02347651 0,0933628 ! response to UV-C GO:0010225 11 6 0,000 0,02347651 0,09320873 ! astrocyte development GO:0014002 15 6 0,000 0,02347651 0,09305518 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02347651 0,09290213 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02347651 0,09274958 ! interaction with symbiont GO:0051702 13 6 0,000 0,02347651 0,09259753 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02347651 0,09244598 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02347651 0,09229492 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02347651 0,09214436 ! response to copper ion GO:0046688 10 6 0,000 0,02347651 0,09199429 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02347651 0,0918447 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02347651 0,0916956 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02347651 0,09154699 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02347651 0,09139886 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02347651 0,0912512 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02347651 0,09110402 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02347651 0,09095731 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02347651 0,09081108 ! hair follicle maturation GO:0048820 7 6 0,000 0,02347651 0,09066532 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02347651 0,09052002 ! Schwann cell development GO:0014044 15 6 0,000 0,02347651 0,09037519 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02347651 0,09023082 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02347651 0,09008691 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02347651 0,08994346 ! subpallium development GO:0021544 10 6 0,000 0,02347651 0,08980046 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02347651 0,08965792 ! histone ubiquitination GO:0016574 8 6 0,000 0,02347651 0,08951584 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02347651 0,0893742 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02347651 0,08923301 ! G2 phase GO:0051319 16 6 0,000 0,02347651 0,08909226 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02347651 0,08895196 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02347651 0,08881209 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02347651 0,08867267 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02347651 0,08853369 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02347651 0,08839514 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02347651 0,08825702 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02347651 0,08811933 ! receptor internalization GO:0031623 10 6 0,000 0,02347651 0,08798208 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02347651 0,08784524 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02347651 0,08770884 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02347651 0,08757286 ! protein deubiquitination GO:0016579 14 6 0,000 0,02347651 0,08743729 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02347651 0,08730215 ! protein destabilization GO:0031648 9 6 0,000 0,02347651 0,08716743 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02347651 0,08703312 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02347651 0,08689922 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02347651 0,08676573 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02347651 0,08663266 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02347651 0,08649999 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02347651 0,08636773 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02347651 0,08623587 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02347651 0,08610441 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02347651 0,08597335 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02347651 0,08584269 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02347651 0,08571243 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02347651 0,08558256 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02347651 0,08545309 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02347651 0,08532401 ! catecholamine transport GO:0051937 9 6 0,000 0,02347651 0,08519531 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02347651 0,08506701 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02347651 0,08493909 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02347651 0,08481155 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02347651 0,0846844 ! maternal placenta development GO:0001893 12 6 0,000 0,02347651 0,08455762 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02347651 0,08443123 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02347651 0,08430521 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02347651 0,08417957 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02347651 0,0840543 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02347651 0,08392941 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02347651 0,08380488 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02347651 0,08368073 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,02360657 0,08401984 ! mesoderm development GO:0007498 119 61 1,000 0,0243447 0,08651897 ! ear development GO:0043583 103 62 1,000 0,02509221 0,08904403 ! tRNA transcription GO:0009304 14 7 0,000 0,02733578 0,09686286 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02733578 0,09672041 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02733578 0,09657839 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02733578 0,09643678 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02733578 0,09629558 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02733578 0,0961548 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02733578 0,09601443 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02733578 0,09587446 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02733578 0,09573491 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02733578 0,09559576 ! prostate gland development GO:0030850 13 7 0,000 0,02733578 0,09545701 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02733578 0,09531867 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02733578 0,09518073 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02733578 0,09504318 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02733578 0,09490603 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02733578 0,09476928 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02733578 0,09463292 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02733578 0,09449696 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02733578 0,09436138 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02733578 0,09422619 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02733578 0,09409139 ! glycolipid transport GO:0046836 10 7 0,000 0,02733578 0,09395697 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02733578 0,09382294 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02733578 0,09368929 ! neuron adhesion GO:0007158 12 7 0,000 0,02733578 0,09355602 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02733578 0,09342313 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02733578 0,09329061 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02733578 0,09315847 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02733578 0,09302671 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02733578 0,09289531 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02733578 0,09276429 ! pericardium development GO:0060039 14 7 0,000 0,02733578 0,09263364 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02733578 0,09250335 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02733578 0,09237343 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02733578 0,09224387 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02733578 0,09211468 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02733578 0,09198585 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02733578 0,09185738 ! lipoprotein transport GO:0042953 14 7 0,000 0,02733578 0,09172926 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02733578 0,09160151 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02733578 0,0914741 ! rhythmic behavior GO:0007622 15 7 0,000 0,02733578 0,09134706 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02733578 0,09122036 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02733578 0,09109402 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02733578 0,09096802 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02733578 0,09084238 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02733578 0,09071708 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02733578 0,09059212 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02733578 0,09046751 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02733578 0,09034324 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02733578 0,09021932 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02733578 0,09009573 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02733578 0,08997248 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02733578 0,08984956 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02733578 0,08972699 ! spinal cord patterning GO:0021511 13 7 0,000 0,02733578 0,08960474 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02733578 0,08948283 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02733578 0,08936125 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02733578 0,08924 ! adrenal gland development GO:0030325 17 7 0,000 0,02733578 0,08911908 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02733578 0,08899849 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02733578 0,08887822 ! ovulation GO:0030728 9 7 0,000 0,02733578 0,08875827 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02733578 0,08863865 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02733578 0,08851936 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02733578 0,08840038 ! microtubule nucleation GO:0007020 20 7 0,000 0,02733578 0,08828172 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02733578 0,08816338 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02733578 0,08804536 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02733578 0,08792765 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02733578 0,08781026 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02733578 0,08769318 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02733578 0,08757641 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02733578 0,08745995 ! galactose metabolic process GO:0006012 13 7 0,000 0,02733578 0,0873438 ! vesicle fusion GO:0006906 17 7 0,000 0,02733578 0,08722796 ! response to dietary excess GO:0002021 8 7 0,000 0,02733578 0,08711243 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02733578 0,0869972 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02733578 0,08688227 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02733578 0,08676765 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02733578 0,08665334 ! organ growth GO:0035265 15 7 0,000 0,02733578 0,08653932 ! purine salvage GO:0043101 10 7 0,000 0,02733578 0,0864256 ! nucleoside transport GO:0015858 8 7 0,000 0,02733578 0,08631218 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02733578 0,08619906 ! parturition GO:0007567 14 7 0,000 0,02733578 0,08608623 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02733578 0,0859737 ! rRNA modification GO:0000154 14 7 0,000 0,02733578 0,08586146 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02733578 0,08574952 ! spindle checkpoint GO:0031577 15 7 0,000 0,02733578 0,08563787 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02733578 0,0855265 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02733578 0,08541543 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02733578 0,08530465 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02733578 0,08519415 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02733578 0,08508393 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02733578 0,08497401 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02733578 0,08486436 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02733578 0,084755 ! fibrinolysis GO:0042730 10 7 0,000 0,02733578 0,08464592 ! eating behavior GO:0042755 7 7 0,000 0,02733578 0,08453712 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02733578 0,0844286 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02733578 0,08432036 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02733578 0,0842124 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02733578 0,08410471 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02733578 0,08399729 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02733578 0,08389015 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02733578 0,08378329 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02733578 0,08367669 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02733578 0,08357037 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02733578 0,08346432 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02733578 0,08335853 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02733578 0,08325301 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02733578 0,08314776 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02733578 0,08304278 ! regulation of meiosis GO:0040020 12 7 0,000 0,02733578 0,08293806 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02733578 0,0828336 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02733578 0,08272941 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02733578 0,08262548 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02733578 0,08252181 ! transcription termination GO:0006353 13 7 0,000 0,02733578 0,0824184 ! response to tumor cell GO:0002347 13 7 0,000 0,02733578 0,08231525 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02733578 0,08221235 ! anaphase GO:0051322 17 7 0,000 0,02733578 0,08210971 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02733578 0,08200733 ! axonal fasciculation GO:0007413 18 7 0,000 0,02733578 0,08190521 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02733578 0,08180333 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02733578 0,08170172 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02733578 0,08160035 ! diuresis GO:0030146 12 7 0,000 0,02733578 0,08149923 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02733578 0,08139837 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02733578 0,08129775 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02733578 0,08119738 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02733578 0,08109726 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02733578 0,08099739 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02733578 0,08089776 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02733578 0,08079838 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02733578 0,08069924 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02733578 0,08060034 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02733578 0,08050169 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02733578 0,08040328 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02733578 0,08030511 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02733578 0,08020717 ! lymph node development GO:0048535 10 7 0,000 0,02733578 0,08010948 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02733578 0,08001202 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02733578 0,0799148 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02733578 0,07981782 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02733578 0,07972107 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02733578 0,07962455 ! adult feeding behavior GO:0008343 9 7 0,000 0,02733578 0,07952827 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02733578 0,07943222 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02733578 0,07933641 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02733578 0,07924082 ! muscle adaptation GO:0043500 14 7 0,000 0,02733578 0,07914546 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02733578 0,07905034 ! retina homeostasis GO:0001895 12 7 0,000 0,02733578 0,07895544 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02733578 0,07886077 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02733578 0,07876632 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02733578 0,07867211 ! protein prenylation GO:0018342 18 7 0,000 0,02733578 0,07857811 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02733578 0,07848435 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02733578 0,0783908 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02733578 0,07829748 ! actin filament organization GO:0007015 148 66 1,000 0,02817437 0,08060349 ! developmental maturation GO:0021700 116 66 1,000 0,02817437 0,08050777 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,02896753 0,08267601 ! activation of MAPK activity GO:0000187 115 67 1,000 0,02896753 0,08257805 ! adaptive immune response GO:0002250 119 67 1,000 0,02896753 0,08248033 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell size GO:0045792 134 69 1,000 0,03058041 0,08696983 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03117992 0,08857011 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03117992 0,08846566 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,03117992 0,08836146 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03117992 0,08825751 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03117992 0,0881538 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03117992 0,08805033 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03117992 0,08794711 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03117992 0,08784412 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03117992 0,08774138 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03117992 0,08763888 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03117992 0,08753662 ! meiotic prophase I GO:0007128 13 8 0,000 0,03117992 0,08743459 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03117992 0,08733281 ! oligopeptide transport GO:0006857 15 8 0,000 0,03117992 0,08723126 ! UTP metabolic process GO:0046051 8 8 0,000 0,03117992 0,08712994 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03117992 0,08702886 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03117992 0,08692802 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03117992 0,08682741 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03117992 0,08672703 ! succinate metabolic process GO:0006105 14 8 0,000 0,03117992 0,08662688 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03117992 0,08652697 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03117992 0,08642728 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03117992 0,08632783 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03117992 0,0862286 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03117992 0,0861296 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03117992 0,08603083 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03117992 0,08593228 ! reflex GO:0060004 16 8 0,000 0,03117992 0,08583396 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03117992 0,08573586 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03117992 0,08563799 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03117992 0,08554034 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03117992 0,08544292 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03117992 0,08534571 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03117992 0,08524873 ! pigment granule organization GO:0048753 16 8 0,000 0,03117992 0,08515196 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03117992 0,08505542 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03117992 0,0849591 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03117992 0,08486299 ! histidine metabolic process GO:0006547 16 8 0,000 0,03117992 0,0847671 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03117992 0,08467142 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03117992 0,08457597 ! glycine catabolic process GO:0006546 13 8 0,000 0,03117992 0,08448072 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03117992 0,08438569 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03117992 0,08429088 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,03117992 0,08419628 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03117992 0,08410188 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03117992 0,08400771 ! melanin metabolic process GO:0006582 15 8 0,000 0,03117992 0,08391374 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03117992 0,08381998 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03117992 0,08372643 ! macrophage activation GO:0042116 12 8 0,000 0,03117992 0,08363309 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03117992 0,08353996 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03117992 0,08344703 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03117992 0,08335431 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03117992 0,0832618 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03117992 0,08316949 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03117992 0,08307739 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03117992 0,08298549 ! osteoblast development GO:0002076 16 8 0,000 0,03117992 0,08289379 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03117992 0,0828023 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03117992 0,082711 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03117992 0,08261991 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03117992 0,08252902 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03117992 0,08243833 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03117992 0,08234784 ! response to UV-B GO:0010224 16 8 0,000 0,03117992 0,08225755 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03117992 0,08216745 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03117992 0,08207755 ! intermediate filament organization GO:0045109 12 8 0,000 0,03117992 0,08198785 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03117992 0,08189834 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03117992 0,08180903 ! cellular extravasation GO:0045123 12 8 0,000 0,03117992 0,08171991 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03117992 0,08163099 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03117992 0,08154226 ! response to antibiotic GO:0046677 11 8 0,000 0,03117992 0,08145373 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03117992 0,08136538 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03117992 0,08127723 ! DNA topological change GO:0006265 12 8 0,000 0,03117992 0,08118927 ! response to tropane GO:0014073 15 8 0,000 0,03117992 0,08110149 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03117992 0,08101391 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,03117992 0,08092652 ! melanosome transport GO:0032402 13 8 0,000 0,03117992 0,08083931 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03117992 0,08075229 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03117992 0,08066546 ! mast cell activation GO:0045576 14 8 0,000 0,03117992 0,08057882 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03117992 0,08049236 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03117992 0,08040609 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03117992 0,08032 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03117992 0,0802341 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03117992 0,08014838 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03117992 0,08006284 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03117992 0,07997749 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03117992 0,07989231 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03117992 0,07980732 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03117992 0,07972251 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03117992 0,07963788 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03117992 0,07955343 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03117992 0,07946915 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03117992 0,07938506 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03117992 0,07930114 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03117992 0,0792174 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03117992 0,07913384 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03117992 0,07905045 ! hormone catabolic process GO:0042447 17 8 0,000 0,03117992 0,07896724 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03117992 0,07888421 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03117992 0,07880135 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03117992 0,07871866 ! ATP catabolic process GO:0006200 11 8 0,000 0,03117992 0,07863614 ! blastocyst growth GO:0001832 19 8 0,000 0,03117992 0,0785538 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03117992 0,07847163 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03117992 0,07838964 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03117992 0,07830781 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03117992 0,07822615 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03117992 0,07814467 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03117992 0,07806335 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03117992 0,0779822 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03117992 0,07790123 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03117992 0,07782042 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03117992 0,07773977 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03117992 0,0776593 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03117992 0,07757899 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03117992 0,07749884 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03117992 0,07741887 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03117992 0,07733905 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03117992 0,0772594 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,03306494 0,08184594 ! carbohydrate transport GO:0008643 110 72 1,000 0,03306494 0,08176182 ! eye development GO:0001654 143 74 1,000 0,03476383 0,08587452 ! axon extension GO:0048675 15 9 0,000 0,03500899 0,08639142 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03500899 0,0863029 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03500899 0,08621457 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03500899 0,08612641 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03500899 0,08603844 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03500899 0,08595065 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03500899 0,08586303 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03500899 0,08577559 ! phosphate transport GO:0006817 19 9 0,000 0,03500899 0,08568833 ! reproductive behavior GO:0019098 19 9 0,000 0,03500899 0,08560125 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03500899 0,08551435 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03500899 0,08542762 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03500899 0,08534107 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03500899 0,08525469 ! GTP metabolic process GO:0046039 9 9 0,000 0,03500899 0,08516849 ! RNA methylation GO:0001510 15 9 0,000 0,03500899 0,08508246 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03500899 0,0849966 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03500899 0,08491092 ! artery development GO:0060840 24 9 0,000 0,03500899 0,08482541 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03500899 0,08474007 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03500899 0,08465491 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03500899 0,08456991 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03500899 0,08448509 ! chemosensory behavior GO:0007635 20 9 0,000 0,03500899 0,08440043 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03500899 0,08431595 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03500899 0,08423163 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03500899 0,08414749 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03500899 0,08406351 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03500899 0,08397969 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03500899 0,08389605 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03500899 0,08381257 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03500899 0,08372926 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03500899 0,08364611 ! protein targeting to ER GO:0045047 22 9 0,000 0,03500899 0,08356313 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03500899 0,08348031 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03500899 0,08339766 ! T cell selection GO:0045058 23 9 0,000 0,03500899 0,08331517 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03500899 0,08323284 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03500899 0,08315067 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03500899 0,08306867 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03500899 0,08298683 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03500899 0,08290515 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03500899 0,08282363 ! mannose metabolic process GO:0006013 13 9 0,000 0,03500899 0,08274227 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03500899 0,08266107 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03500899 0,08258003 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03500899 0,08249915 ! receptor clustering GO:0043113 18 9 0,000 0,03500899 0,08241843 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03500899 0,08233786 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03500899 0,08225745 ! ruffle organization GO:0031529 15 9 0,000 0,03500899 0,0821772 ! retinol metabolic process GO:0042572 18 9 0,000 0,03500899 0,08209711 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03500899 0,08201717 ! behavioral fear response GO:0001662 22 9 0,000 0,03500899 0,08193739 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03500899 0,08185776 GO:0007351|tripartite regional subdivision, ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03500899 0,08177828 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03500899 0,08169897 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03500899 0,0816198 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03500899 0,08154079 ! segment specification GO:0007379 13 9 0,000 0,03500899 0,08146193 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03500899 0,08138322 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03500899 0,08130467 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03500899 0,08122626 ! response to amine stimulus GO:0014075 13 9 0,000 0,03500899 0,08114801 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03500899 0,08106991 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03500899 0,08099196 ! erythrocyte development GO:0048821 15 9 0,000 0,03500899 0,08091415 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03500899 0,0808365 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03500899 0,080759 ! renal water homeostasis GO:0003091 14 9 0,000 0,03500899 0,08068164 ! postreplication repair GO:0006301 22 9 0,000 0,03500899 0,08060443 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03500899 0,08052737 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03500899 0,08045046 ! icosanoid secretion GO:0032309 15 9 0,000 0,03500899 0,0803737 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03500899 0,08029708 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03500899 0,0802206 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03500899 0,08014428 ! regulation of cell division GO:0051302 15 9 0,000 0,03500899 0,08006809 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03500899 0,07999205 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03500899 0,07991616 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03500899 0,07984041 ! sterol catabolic process GO:0016127 11 9 0,000 0,03500899 0,0797648 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03500899 0,07968934 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03500899 0,07961402 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03500899 0,07953884 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03500899 0,0794638 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03500899 0,07938891 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03500899 0,07931416 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03500899 0,07923954 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03500899 0,07916507 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03500899 0,07909074 ! purine base metabolic process GO:0006144 21 9 0,000 0,03500899 0,07901654 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03500899 0,07894249 ! pigment granule transport GO:0051904 17 9 0,000 0,03500899 0,07886857 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03500899 0,07879479 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,03500899 0,07872115 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03500899 0,07864765 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03500899 0,07857428 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03500899 0,07850106 ! mitochondrion localization GO:0051646 15 9 0,000 0,03500899 0,07842796 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,0373744 0,08364913 ! blood coagulation GO:0007596 146 78 1,000 0,03826088 0,0855536 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 1,000 0,03826088 0,08547417 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03882306 0,08664961 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03882306 0,0865693 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03882306 0,08648915 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03882306 0,08640914 ! synapsis GO:0007129 13 10 0,000 0,03882306 0,08632928 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03882306 0,08624956 ! N-glycan processing GO:0006491 20 10 0,000 0,03882306 0,08617 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03882306 0,08609058 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03882306 0,08601131 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03882306 0,08593218 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03882306 0,0858532 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03882306 0,08577436 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,03882306 0,08569567 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03882306 0,08561712 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03882306 0,08553872 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03882306 0,08546046 ! androgen metabolic process GO:0008209 17 10 0,000 0,03882306 0,08538234 ! phospholipid efflux GO:0033700 16 10 0,000 0,03882306 0,08530436 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03882306 0,08522653 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03882306 0,08514884 ! pathogenesis GO:0009405 13 10 0,000 0,03882306 0,08507129 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03882306 0,08499388 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03882306 0,08491662 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03882306 0,08483949 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03882306 0,0847625 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03882306 0,08468566 ! endoderm development GO:0007492 16 10 0,000 0,03882306 0,08460895 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03882306 0,08453238 ! arginine catabolic process GO:0006527 13 10 0,000 0,03882306 0,08445595 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03882306 0,08437966 ! proline metabolic process GO:0006560 13 10 0,000 0,03882306 0,0843035 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03882306 0,08422748 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03882306 0,0841516 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03882306 0,08407586 ! V(D)J recombination GO:0033151 28 10 0,000 0,03882306 0,08400025 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03882306 0,08392478 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03882306 0,08384944 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03882306 0,08377424 ! B cell proliferation GO:0042100 18 10 0,000 0,03882306 0,08369917 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03882306 0,08362424 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03882306 0,08354944 ! multicellular organism growth GO:0035264 18 10 0,000 0,03882306 0,08347478 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03882306 0,08340025 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03882306 0,08332585 ! epithelial cell development GO:0002064 20 10 0,000 0,03882306 0,08325159 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03882306 0,08317745 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03882306 0,08310345 ! macroautophagy GO:0016236 17 10 0,000 0,03882306 0,08302958 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03882306 0,08295584 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03882306 0,08288223 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03882306 0,08280876 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,03882306 0,08273541 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03882306 0,08266219 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03882306 0,08258911 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03882306 0,08251615 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03882306 0,08244332 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03882306 0,08237062 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03882306 0,08229804 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03882306 0,0822256 ! response to dsRNA GO:0043331 20 10 0,000 0,03882306 0,08215328 ! DNA ligation GO:0006266 19 10 0,000 0,03882306 0,08208109 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03882306 0,08200902 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03882306 0,08193709 ! melanosome localization GO:0032400 16 10 0,000 0,03882306 0,08186527 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03882306 0,08179359 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03882306 0,08172203 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03882306 0,08165059 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03882306 0,08157928 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03882306 0,0815081 ! mRNA cleavage GO:0006379 17 10 0,000 0,03882306 0,08143703 ! protein sumoylation GO:0016925 15 10 0,000 0,03882306 0,0813661 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03882306 0,08129528 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03882306 0,08122459 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03882306 0,08115402 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03882306 0,08108358 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03882306 0,08101325 ! salivary gland development GO:0007431 27 10 0,000 0,03882306 0,08094305 ! prophase GO:0051324 15 10 0,000 0,03882306 0,08087297 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03882306 0,08080301 ! apical protein localization GO:0045176 15 10 0,000 0,03882306 0,08073317 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03882306 0,08066345 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03882306 0,08059386 ! midbrain development GO:0030901 13 10 0,000 0,03882306 0,08052438 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03882306 0,08045502 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03882306 0,08038578 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03882306 0,08031666 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03882306 0,08024766 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03882306 0,08017878 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03882306 0,08011002 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03882306 0,08004137 ! detection of calcium ion GO:0005513 23 10 0,000 0,03882306 0,07997284 ! oocyte development GO:0048599 17 10 0,000 0,03882306 0,07990443 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03882306 0,07983614 ! blastocyst formation GO:0001825 17 10 0,000 0,03882306 0,07976796 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03882306 0,0796999 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03882306 0,07963195 ! activation of innate immune response GO:0002218 12 10 0,000 0,03882306 0,07956412 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03882306 0,07949641 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03882306 0,07942881 ! response to nicotine GO:0035094 20 10 0,000 0,03882306 0,07936132 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03882306 0,07929395 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03882306 0,0792267 ! localization within membrane GO:0051668 20 10 0,000 0,03882306 0,07915956 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,0409681 0,08346252 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04262218 0,08675885 ! respiratory burst GO:0045730 17 11 0,000 0,04262218 0,08668551 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04262218 0,08661229 ! neuron fate specification GO:0048665 17 11 0,000 0,04262218 0,0865392 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04262218 0,08646624 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04262218 0,08639339 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04262218 0,08632067 ! thyroid gland development GO:0030878 26 11 0,000 0,04262218 0,08624807 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04262218 0,08617559 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04262218 0,08610324 ! response to pain GO:0048265 24 11 0,000 0,04262218 0,086031 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04262218 0,08595889 ! T cell proliferation GO:0042098 26 11 0,000 0,04262218 0,0858869 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04262218 0,08581503 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,04262218 0,08574328 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04262218 0,08567164 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04262218 0,08560013 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04262218 0,08552874 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04262218 0,08545746 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04262218 0,08538631 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04262218 0,08531527 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04262218 0,08524435 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04262218 0,08517355 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04262218 0,08510287 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04262218 0,0850323 ! lipid digestion GO:0044241 18 11 0,000 0,04262218 0,08496185 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04262218 0,08489152 ! UV protection GO:0009650 19 11 0,000 0,04262218 0,0848213 ! adult heart development GO:0007512 14 11 0,000 0,04262218 0,0847512 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04262218 0,08468122 ! temperature homeostasis GO:0001659 17 11 0,000 0,04262218 0,08461135 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04262218 0,0845416 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04262218 0,08447196 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04262218 0,08440243 ! regulation of organ growth GO:0046620 13 11 0,000 0,04262218 0,08433302 ! pigment granule localization GO:0051875 20 11 0,000 0,04262218 0,08426373 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04262218 0,08419455 ! vasoconstriction GO:0042310 18 11 0,000 0,04262218 0,08412548 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04262218 0,08405652 ! embryonic axis specification GO:0000578 18 11 0,000 0,04262218 0,08398768 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04262218 0,08391895 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04262218 0,08385033 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04262218 0,08378183 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04262218 0,08371343 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04262218 0,08364515 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04262218 0,08357698 ! zymogen activation GO:0031638 15 11 0,000 0,04262218 0,08350892 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04262218 0,08344097 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04262218 0,08337314 ! nucleosome positioning GO:0016584 15 11 0,000 0,04262218 0,08330541 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04262218 0,08323779 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04262218 0,08317028 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04262218 0,08310288 ! acid secretion GO:0046717 18 11 0,000 0,04262218 0,08303559 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04262218 0,08296841 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04262218 0,08290134 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04262218 0,08283438 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04262218 0,08276752 ! oocyte differentiation GO:0009994 18 11 0,000 0,04262218 0,08270077 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04262218 0,08263413 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,04262218 0,0825676 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04262218 0,08250117 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04262218 0,08243485 ! germ cell migration GO:0008354 25 11 0,000 0,04262218 0,08236864 ! embryonic gut development GO:0048566 15 11 0,000 0,04262218 0,08230253 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04262218 0,08223653 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04262218 0,08217064 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04262218 0,08210485 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04262218 0,08203917 ! defense response to fungus GO:0050832 13 11 0,000 0,04262218 0,08197359 ! developmental induction GO:0031128 19 11 0,000 0,04262218 0,08190811 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04262218 0,08184274 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04262218 0,08177748 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04262218 0,08171232 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04262218 0,08164726 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04262218 0,0815823 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04262218 0,08151745 ! hemostasis GO:0007599 158 84 1,000 0,04374541 0,08359925 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,04468641 0,08532977 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0464064 0,08854386 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0464064 0,0884737 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0464064 0,08840365 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0464064 0,08833371 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0464064 0,08826388 ! cartilage condensation GO:0001502 20 12 0,000 0,0464064 0,08819416 ! mating GO:0007618 17 12 0,000 0,0464064 0,08812455 ! protein complex disassembly GO:0043241 27 12 0,000 0,0464064 0,08805505 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0464064 0,08798567 ! hippocampus development GO:0021766 26 12 0,000 0,0464064 0,08791639 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0464064 0,08784721 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0464064 0,08777815 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0464064 0,0877092 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0464064 0,08764035 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0464064 0,08757162 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0464064 0,08750299 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0464064 0,08743446 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0464064 0,08736605 ! drug transport GO:0015893 16 12 0,000 0,0464064 0,08729774 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0464064 0,08722954 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0464064 0,08716144 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0464064 0,08709345 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0464064 0,08702557 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0464064 0,0869578 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0464064 0,08689012 ! forebrain cell migration GO:0021885 21 12 0,000 0,0464064 0,08682256 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0464064 0,0867551 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0464064 0,08668774 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0464064 0,08662049 ! fear response GO:0042596 26 12 0,000 0,0464064 0,08655334 ! monoamine transport GO:0015844 18 12 0,000 0,0464064 0,0864863 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0464064 0,08641936 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0464064 0,08635252 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0464064 0,08628579 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0464064 0,08621916 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0464064 0,08615263 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0464064 0,08608621 ! protein homotetramerization GO:0051289 21 12 0,000 0,0464064 0,08601988 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0464064 0,08595366 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0464064 0,08588755 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0464064 0,08582153 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0464064 0,08575561 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0464064 0,0856898 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0464064 0,08562409 ! cranial nerve development GO:0021545 20 12 0,000 0,0464064 0,08555847 ! fucose catabolic process GO:0019317 22 12 0,000 0,0464064 0,08549296 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0464064 0,08542755 ! histone methylation GO:0016571 26 12 0,000 0,0464064 0,08536224 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0464064 0,08529703 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0464064 0,08523192 ! gland morphogenesis GO:0022612 29 12 0,000 0,0464064 0,0851669 ! T cell homeostasis GO:0043029 25 12 0,000 0,0464064 0,08510199 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0464064 0,08503717 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0464064 0,08497246 ! spleen development GO:0048536 22 12 0,000 0,0464064 0,08490784 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0464064 0,08484332 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0464064 0,0847789 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0464064 0,08471457 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0464064 0,08465035 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0464064 0,08458622 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,0464064 0,08452219 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0464064 0,08445825 ! response to cold GO:0009409 17 12 0,000 0,0464064 0,08439441 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0464064 0,08433067 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0464064 0,08426703 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,04852462 0,08804694 ! ossification GO:0001503 188 90 1,000 0,04950236 0,08975334 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0501758 0,09090585 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,0501758 0,09083745 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,0501758 0,09076915 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,0501758 0,09070096 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,0501758 0,09063286 ! lipid localization GO:0010876 28 13 0,000 0,0501758 0,09056487 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,0501758 0,09049698 ! organelle fusion GO:0048284 32 13 0,000 0,0501758 0,09042919 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,0501758 0,09036151 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,0501758 0,09029392 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,0501758 0,09022644 ! endocrine pancreas development GO:0031018 22 13 0,000 0,0501758 0,09015905 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,0501758 0,09009177 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,0501758 0,09002459 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,0501758 0,08995751 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0501758 0,08989052 ! methionine metabolic process GO:0006555 27 13 0,000 0,0501758 0,08982364 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,0501758 0,08975686 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,0501758 0,08969017 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,0501758 0,08962359 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 0,000 0,0501758 0,0895571 ! response to X-ray GO:0010165 25 13 0,000 0,0501758 0,08949071 ! cytokine metabolic process GO:0042107 22 13 0,000 0,0501758 0,08942442 ! exocrine system development GO:0035272 32 13 0,000 0,0501758 0,08935823 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,0501758 0,08929214 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,0501758 0,08922614 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,0501758 0,08916025 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,0501758 0,08909445 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,0501758 0,08902874 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,0501758 0,08896313 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,0501758 0,08889762 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,0501758 0,08883221 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,0501758 0,08876689 ! regulation of cellular pH GO:0030641 22 13 0,000 0,0501758 0,08870167 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0501758 0,08863654 ! ribosome assembly GO:0042255 17 13 0,000 0,0501758 0,08857151 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,0501758 0,08850658 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,0501758 0,08844174 ! chromatin silencing GO:0006342 26 13 0,000 0,0501758 0,08837699 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,0501758 0,08831234 ! regulation of epidermis development GO:0045682 19 13 0,000 0,0501758 0,08824779 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0501758 0,08818333 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,0501758 0,08811896 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,0501758 0,08805469 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0501758 0,08799051 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,0501758 0,08792642 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,0501758 0,08786243 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,0501758 0,08779853 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,0501758 0,08773472 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,0501758 0,087671 ! insulin secretion GO:0030073 23 13 0,000 0,0501758 0,08760738 ! actin filament polymerization GO:0030041 24 13 0,000 0,0501758 0,08754385 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,0501758 0,08748042 ! acrosome reaction GO:0007340 18 13 0,000 0,0501758 0,08741707 ! bone development GO:0060348 189 91 1,000 0,05048724 0,08789602 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,05247811 0,09129597 GO:0010498|proteasomal protein catabolic process, ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,05247811 0,09123 ! rRNA transcription GO:0009303 25 14 0,000 0,05393042 0,09368707 ! lactation GO:0007595 26 14 0,000 0,05393042 0,09361947 ! reproductive cellular process GO:0048610 20 14 0,000 0,05393042 0,09355198 ! tRNA modification GO:0006400 20 14 0,000 0,05393042 0,09348457 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05393042 0,09341727 ! regulation of S phase GO:0033261 23 14 0,000 0,05393042 0,09335006 ! water transport GO:0006833 21 14 0,000 0,05393042 0,09328295 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05393042 0,09321594 ! non-recombinational repair GO:0000726 25 14 0,000 0,05393042 0,09314902 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05393042 0,0930822 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05393042 0,09301548 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05393042 0,09294885 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,05393042 0,09288231 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05393042 0,09281587 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05393042 0,09274953 ! palate development GO:0060021 31 14 0,000 0,05393042 0,09268328 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05393042 0,09261712 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,05393042 0,09255106 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05393042 0,0924851 ! arginine metabolic process GO:0006525 17 14 0,000 0,05393042 0,09241922 ! regulation of heart rate GO:0002027 24 14 0,000 0,05393042 0,09235344 ! organic alcohol transport GO:0015850 29 14 0,000 0,05393042 0,09228776 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05393042 0,09222217 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,05393042 0,09215667 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,05393042 0,09209126 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05393042 0,09202595 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05393042 0,09196073 ! L-amino acid transport GO:0015807 30 14 0,000 0,05393042 0,0918956 ! bone mineralization GO:0030282 17 14 0,000 0,05393042 0,09183057 ! stem cell development GO:0048864 43 14 0,000 0,05393042 0,09176562 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05393042 0,09170077 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,05393042 0,09163601 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05393042 0,09157134 ! cerebellum development GO:0021549 21 14 0,000 0,05393042 0,09150676 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05393042 0,09144228 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05393042 0,09137788 ! response to gamma radiation GO:0010332 28 14 0,000 0,05393042 0,09131357 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05393042 0,09124936 ! cofactor transport GO:0051181 26 14 0,000 0,05393042 0,09118523 ! NADP metabolic process GO:0006739 24 14 0,000 0,05393042 0,0911212 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05393042 0,09105726 ! intestinal absorption GO:0050892 25 14 0,000 0,05393042 0,0909934 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05393042 0,09092964 ! oxygen transport GO:0015671 21 14 0,000 0,05393042 0,09086596 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05393042 0,09080237 ! male genitalia development GO:0030539 24 14 0,000 0,05393042 0,09073887 ! regulation of axon extension GO:0030516 37 14 0,000 0,05393042 0,09067546 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,05393042 0,09061214 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05393042 0,09054891 ! forebrain development GO:0030900 188 95 1,000 0,05449667 0,09143583 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05767032 0,09669324 ! positive regulation of cell size GO:0045793 27 15 0,000 0,05767032 0,0966259 ! superoxide anion generation GO:0042554 20 15 0,000 0,05767032 0,09655866 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05767032 0,09649151 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05767032 0,09642446 ! copper ion transport GO:0006825 20 15 0,000 0,05767032 0,0963575 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05767032 0,09629063 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05767032 0,09622385 ! sulfate transport GO:0008272 23 15 0,000 0,05767032 0,09615717 ! response to cAMP GO:0051591 22 15 0,000 0,05767032 0,09609058 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05767032 0,09602408 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05767032 0,09595767 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05767032 0,09589136 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05767032 0,09582513 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05767032 0,095759 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05767032 0,09569296 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05767032 0,09562701 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05767032 0,09556115 ! vesicle coating GO:0006901 33 15 0,000 0,05767032 0,09549538 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05767032 0,09542971 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,05767032 0,09536412 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05767032 0,09529862 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,05767032 0,09523322 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05767032 0,0951679 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05767032 0,09510267 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05767032 0,09503753 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05767032 0,09497248 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05767032 0,09490752 ! histone deacetylation GO:0016575 20 15 0,000 0,05767032 0,09484265 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05767032 0,09477787 ! tissue regeneration GO:0042246 26 15 0,000 0,05767032 0,09471317 ! water homeostasis GO:0030104 27 15 0,000 0,05767032 0,09464856 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05767032 0,09458405 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05767032 0,09451961 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05767032 0,09445527 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05767032 0,09439102 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05767032 0,09432685 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05767032 0,09426277 ! cell killing GO:0001906 29 15 0,000 0,05767032 0,09419877 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,05767032 0,09413487 ! detection of bacterium GO:0016045 18 15 0,000 0,05767032 0,09407105 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05767032 0,09400731 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05767032 0,09394367 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05767032 0,0938801 ! peptide hormone processing GO:0016486 23 15 0,000 0,05767032 0,09381663 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,05861466 0,09528844 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 1,000 0,05966062 0,09692332 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06139556 0,09967458 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,06139556 0,09960737 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06139556 0,09954025 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06139556 0,09947322 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06139556 0,09940628 ! bone remodeling GO:0046849 27 16 0,000 0,06139556 0,09933943 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06139556 0,09927267 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06139556 0,09920599 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06139556 0,09913941 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06139556 0,09907292 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06139556 0,09900652 ! startle response GO:0001964 28 16 0,000 0,06139556 0,09894021 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06139556 0,09887398 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06139556 0,09880784 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06139556 0,0987418 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06139556 0,09867584 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06139556 0,09860996 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06139556 0,09854418 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06139556 0,09847848 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06139556 0,09841288 ! response to osmotic stress GO:0006970 25 16 0,000 0,06139556 0,09834735 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06139556 0,09828192 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06139556 0,09821657 ! fructose metabolic process GO:0006000 25 16 0,000 0,06139556 0,09815131 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06139556 0,09808614 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06139556 0,09802105 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06139556 0,09795605 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06139556 0,09789114 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06139556 0,09782631 ! axon cargo transport GO:0008088 43 16 0,000 0,06139556 0,09776157 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06139556 0,09769691 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06139556 0,09763234 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,06139556 0,09756785 ! DNA replication initiation GO:0006270 27 16 0,000 0,06139556 0,09750345 ! neuron recognition GO:0008038 35 16 0,000 0,06139556 0,09743913 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06139556 0,0973749 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06139556 0,09731076 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06139556 0,09724669 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06139556 0,09718271 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06139556 0,09711882 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06139556 0,09705501 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06139556 0,09699128 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06139556 0,09692764 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06139556 0,09686408 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06139556 0,09680061 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,06139556 0,09673721 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06139556 0,0966739 ! defense response to virus GO:0051607 37 16 0,000 0,06139556 0,09661068 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0651062 0,10238269 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,0651062 0,10231582 ! metencephalon development GO:0022037 30 17 0,000 0,0651062 0,10224904 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,0651062 0,10218234 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,0651062 0,10211573 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0651062 0,1020492 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0651062 0,10198276 ! signal complex assembly GO:0007172 41 17 0,000 0,0651062 0,10191641 ! endothelial cell migration GO:0043542 28 17 0,000 0,0651062 0,10185014 ! inositol metabolic process GO:0006020 28 17 0,000 0,0651062 0,10178397 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0651062 0,10171787 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0651062 0,10165186 ! glial cell development GO:0021782 27 17 0,000 0,0651062 0,10158594 ! limbic system development GO:0021761 36 17 0,000 0,0651062 0,10152011 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0651062 0,10145435 ! adult walking behavior GO:0007628 33 17 0,000 0,0651062 0,10138869 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0651062 0,10132311 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0651062 0,10125761 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,0651062 0,1011922 ! myoblast differentiation GO:0045445 45 17 0,000 0,0651062 0,10112687 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0651062 0,10106163 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,0651062 0,10099647 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0651062 0,10093139 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0651062 0,1008664 ! glycine metabolic process GO:0006544 28 17 0,000 0,0651062 0,10080149 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0651062 0,10073667 ! NAD metabolic process GO:0019674 29 17 0,000 0,0651062 0,10067193 ! membrane budding GO:0006900 37 17 0,000 0,0651062 0,10060727 ! DNA integration GO:0015074 29 17 0,000 0,0651062 0,1005427 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,0651062 0,10047821 ! regulation of protein binding GO:0043393 33 17 0,000 0,0651062 0,1004138 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0651062 0,10034947 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0651062 0,10028523 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0651062 0,10022106 ! genitalia development GO:0048806 30 17 0,000 0,0651062 0,10015698 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,0651062 0,10009299 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0651062 0,10002907 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,0651062 0,09996523 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0651062 0,09990148 ! steroid catabolic process GO:0006706 31 17 0,000 0,0651062 0,09983781 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0651062 0,09977422 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,0651062 0,09971071 ! gas transport GO:0015669 25 17 0,000 0,0651062 0,09964728 ! organic cation transport GO:0015695 31 17 0,000 0,0651062 0,09958393 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0651062 0,09952066 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0651062 0,09945747 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0651062 0,09939437 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,0651062 0,09933134 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06880229 0,10490388 ! neuron maturation GO:0042551 42 18 0,000 0,06880229 0,10483744 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06880229 0,10477109 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,06880229 0,10470482 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,06880229 0,10463863 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06880229 0,10457253 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06880229 0,10450651 ! memory GO:0007613 31 18 0,000 0,06880229 0,10444058 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06880229 0,10437473 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06880229 0,10430896 ! patterning of blood vessels GO:0001569 39 18 0,000 0,06880229 0,10424327 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,06880229 0,10417767 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,06880229 0,10411215 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,06880229 0,10404671 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,06880229 0,10398136 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06880229 0,10391608 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,06880229 0,10385089 ! response to fungus GO:0009620 21 18 0,000 0,06880229 0,10378578 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,06880229 0,10372075 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,06880229 0,1036558 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,06880229 0,10359094 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,06880229 0,10352615 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06880229 0,10346145 ! vitamin transport GO:0051180 27 18 0,000 0,06880229 0,10339683 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,06880229 0,10333228 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06880229 0,10326782 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,06880229 0,10320344 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,06880229 0,10313914 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,06880229 0,10307492 ! nerve development GO:0021675 28 18 0,000 0,06880229 0,10301078 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06880229 0,10294672 ! protein secretion GO:0009306 39 19 0,000 0,0724839 0,10838798 ! positive regulation of translation GO:0045727 30 19 0,000 0,0724839 0,10832065 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0724839 0,10825342 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0724839 0,10818626 ! skin development GO:0043588 36 19 0,000 0,0724839 0,10811919 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0724839 0,1080522 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0724839 0,1079853 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0724839 0,10791847 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0724839 0,10785173 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0724839 0,10778508 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0724839 0,1077185 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0724839 0,10765201 ! cerebral cortex development GO:0021987 36 19 0,000 0,0724839 0,1075856 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,0724839 0,10751927 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,0724839 0,10745302 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0724839 0,10738686 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0724839 0,10732077 ! peptide cross-linking GO:0018149 37 19 0,000 0,0724839 0,10725477 ! protein export from nucleus GO:0006611 36 19 0,000 0,0724839 0,10718885 ! heart process GO:0003015 30 19 0,000 0,0724839 0,10712301 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0724839 0,10705725 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0724839 0,10699157 ! visual learning GO:0008542 36 19 0,000 0,0724839 0,10692597 ! cellular pigmentation GO:0033059 36 19 0,000 0,0724839 0,10686045 ! G1 phase GO:0051318 40 19 0,000 0,0724839 0,10679501 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0724839 0,10672965 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0724839 0,10666437 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0724839 0,10659918 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0724839 0,10653406 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0724839 0,10646902 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0724839 0,10640406 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0724839 0,10633918 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0724839 0,10627438 ! cilium assembly GO:0042384 37 19 0,000 0,0724839 0,10620965 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0724839 0,10614501 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,07615106 0,11144736 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,07615106 0,11137961 ! positive regulation of ossification GO:0045778 47 20 0,000 0,07615106 0,11131194 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,07615106 0,11124436 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,07615106 0,11117686 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,07615106 0,11110944 ! cAMP metabolic process GO:0046058 36 20 0,000 0,07615106 0,1110421 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,07615106 0,11097484 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,07615106 0,11090766 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,07615106 0,11084057 ! response to alkaloid GO:0043279 38 20 0,000 0,07615106 0,11077355 ! retinoid metabolic process GO:0001523 32 20 0,000 0,07615106 0,11070662 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,07615106 0,11063977 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,07615106 0,110573 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,07615106 0,11050631 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,07615106 0,1104397 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,07615106 0,11037317 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,07615106 0,11030672 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,07615106 0,11024035 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,07615106 0,11017406 ! body fluid secretion GO:0007589 31 20 0,000 0,07615106 0,11010785 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,07615106 0,11004172 ! peptide secretion GO:0002790 35 20 0,000 0,07615106 0,10997567 ! stem cell differentiation GO:0048863 53 20 0,000 0,07615106 0,10990969 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,07615106 0,1098438 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,07615106 0,10977799 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,07615106 0,10971225 ! sensory perception of pain GO:0019233 30 20 0,000 0,07615106 0,10964659 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,07615106 0,10958102 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,07615106 0,10951552 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,07615106 0,10945009 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,07615106 0,10938475 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,07615106 0,10931949 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,07615106 0,1092543 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,07615106 0,10918919 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,07615106 0,10912416 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,07615106 0,1090592 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,07615106 0,10899432 ! actin filament-based movement GO:0030048 43 20 0,000 0,07615106 0,10892952 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,07615106 0,1088648 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,07615106 0,10880015 ! negative regulation of translation GO:0017148 29 20 0,000 0,07615106 0,10873558 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,07615106 0,10867109 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,07615106 0,10860667 ! regulation of cell killing GO:0031341 42 21 0,000 0,07980385 0,11374886 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,07980385 0,11368151 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,07980385 0,11361424 ! hormone secretion GO:0046879 38 21 0,000 0,07980385 0,11354706 ! glycerol metabolic process GO:0006071 34 21 0,000 0,07980385 0,11347995 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,07980385 0,11341292 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,07980385 0,11334597 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,07980385 0,1132791 ! axis specification GO:0009798 38 21 0,000 0,07980385 0,11321231 ! ovarian follicle development GO:0001541 35 21 0,000 0,07980385 0,11314559 ! smooth muscle contraction GO:0006939 46 21 0,000 0,07980385 0,11307896 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,07980385 0,1130124 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,07980385 0,11294592 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,07980385 0,11287952 ! cell aging GO:0007569 44 21 0,000 0,07980385 0,1128132 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,07980385 0,11274696 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,07980385 0,11268079 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,07980385 0,1126147 ! cytolysis GO:0019835 24 21 0,000 0,07980385 0,11254869 ! vasodilation GO:0042311 39 21 0,000 0,07980385 0,11248276 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,07980385 0,1124169 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,07980385 0,11235112 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,07980385 0,11228542 ! oogenesis GO:0048477 36 21 0,000 0,07980385 0,1122198 ! DNA modification GO:0006304 34 21 0,000 0,07980385 0,11215425 ! collagen fibril organization GO:0030199 59 21 0,000 0,07980385 0,11208877 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,07980385 0,11202338 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,07980385 0,11195806 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,07980385 0,11189282 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,07980385 0,11182765 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,07980385 0,11176256 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,07980385 0,11169754 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,07980385 0,1116326 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,07980385 0,11156773 ! collagen catabolic process GO:0030574 28 21 0,000 0,07980385 0,11150295 ! sperm-egg recognition GO:0035036 21 21 0,000 0,07980385 0,11143823 ! gut development GO:0048565 39 21 0,000 0,07980385 0,11137359 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,08344232 0,1163839 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,08344232 0,11631647 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08344232 0,11624912 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08344232 0,11618184 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,08344232 0,11611465 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,08344232 0,11604753 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08344232 0,11598049 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,08344232 0,11591353 ! regeneration GO:0031099 41 22 0,000 0,08344232 0,11584664 ! keratinization GO:0031424 28 22 0,000 0,08344232 0,11577983 ! sensory perception of taste GO:0050909 28 22 0,000 0,08344232 0,1157131 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,08344232 0,11564644 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,08344232 0,11557987 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08344232 0,11551336 ! vacuolar transport GO:0007034 36 22 0,000 0,08344232 0,11544694 ! lysosome organization GO:0007040 41 22 0,000 0,08344232 0,11538059 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08344232 0,11531432 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,08344232 0,11524812 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,08344232 0,115182 ! fucose metabolic process GO:0006004 39 22 0,000 0,08344232 0,11511596 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08344232 0,11504999 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,08344232 0,11498409 ! ureteric bud development GO:0001657 43 22 0,000 0,08344232 0,11491827 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,08344232 0,11485253 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,08344232 0,11478686 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,08344232 0,11472127 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,08344232 0,11465575 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,08344232 0,11459031 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08344232 0,11452494 ! sarcomere organization GO:0045214 30 22 0,000 0,08344232 0,11445965 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,08344232 0,11439443 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08344232 0,11432929 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,08344232 0,11426422 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,08344232 0,11419922 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,08344232 0,1141343 ! protein stabilization GO:0050821 39 22 0,000 0,08344232 0,11406945 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,08706652 0,11895631 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,08706652 0,11888879 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,08706652 0,11882136 ! gluconeogenesis GO:0006094 33 23 0,000 0,08706652 0,118754 ! viral genome replication GO:0019079 41 23 0,000 0,08706652 0,11868672 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,08706652 0,11861951 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,08706652 0,11855238 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,08706652 0,11848533 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,08706652 0,11841835 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,08706652 0,11835144 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,08706652 0,11828462 ! visual behavior GO:0007632 42 23 0,000 0,08706652 0,11821786 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,08706652 0,11815119 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,08706652 0,11808459 ! response to ethanol GO:0045471 46 23 0,000 0,08706652 0,11801806 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,08706652 0,11795161 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,08706652 0,11788523 ! peroxisome organization GO:0007031 37 23 0,000 0,08706652 0,11781893 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,08706652 0,1177527 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,08706652 0,11768655 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,08706652 0,11762047 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,08706652 0,11755446 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,08706652 0,11748853 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,08706652 0,11742268 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,08706652 0,11735689 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,08706652 0,11729119 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,08706652 0,11722555 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,08706652 0,11715999 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,08706652 0,1170945 ! fatty acid transport GO:0015908 44 23 0,000 0,08706652 0,11702908 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,08706652 0,11696374 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,08706652 0,11689847 ! hormone transport GO:0009914 40 23 0,000 0,08706652 0,11683327 ! cell-cell recognition GO:0009988 25 23 0,000 0,08706652 0,11676815 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,08706652 0,1167031 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,08706652 0,11663812 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,08706652 0,11657321 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,08706652 0,11650837 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,08706652 0,11644361 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,09067652 0,12120428 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,09067652 0,12113698 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,09067652 0,12106975 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,09067652 0,1210026 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,09067652 0,12093553 ! vesicle docking GO:0048278 47 24 0,000 0,09067652 0,12086853 ! spinal cord development GO:0021510 47 24 0,000 0,09067652 0,1208016 ! vacuole organization GO:0007033 43 24 0,000 0,09067652 0,12073475 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,09067652 0,12066797 ! digestive system process GO:0022600 39 24 0,000 0,09067652 0,12060127 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,09067652 0,12053464 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,09067652 0,12046808 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,09067652 0,1204016 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,09067652 0,12033519 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,09067652 0,12026885 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,09067652 0,12020259 ! membrane depolarization GO:0051899 39 24 0,000 0,09067652 0,1201364 ! pallium development GO:0021543 49 24 0,000 0,09067652 0,12007028 ! pentose metabolic process GO:0019321 35 24 0,000 0,09067652 0,12000423 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,09067652 0,11993826 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,09067652 0,11987236 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,09067652 0,11980653 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,09067652 0,11974078 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,09067652 0,11967509 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,09067652 0,11960948 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,09067652 0,11954394 ! regulation of amine transport GO:0051952 40 24 0,000 0,09067652 0,11947848 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,09427235 0,12414848 ! myelination GO:0042552 45 25 0,000 0,09427235 0,12408057 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,09427235 0,12401273 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,09427235 0,12394496 ! phototransduction GO:0007602 33 25 0,000 0,09427235 0,12387727 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,09427235 0,12380965 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,09427235 0,1237421 ! sperm motility GO:0030317 31 25 0,000 0,09427235 0,12367463 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,09427235 0,12360724 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,09427235 0,12353991 ! receptor metabolic process GO:0043112 46 25 0,000 0,09427235 0,12347266 ! chromosome condensation GO:0030261 45 25 0,000 0,09427235 0,12340548 ! response to starvation GO:0042594 42 25 0,000 0,09427235 0,12333838 ! osteoblast differentiation GO:0001649 60 25 0,000 0,09427235 0,12327135 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,09427235 0,12320439 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,09427235 0,1231375 ! negative regulation of cell development GO:0010721 73 25 0,000 0,09427235 0,12307069 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,09427235 0,12300395 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,09427235 0,12293728 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,09427235 0,12287068 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,09427235 0,12280416 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,09427235 0,1227377 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,09427235 0,12267132 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,09427235 0,12260501 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,09427235 0,12253878 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,09427235 0,12247261 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,09427235 0,12240652 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,09427235 0,12234049 ! telomere organization GO:0032200 43 25 0,000 0,09427235 0,12227454 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,09427235 0,12220866 GO:0060606|tube closure, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,09785409 0,12678349 ! embryonic pattern specification GO:0009880 44 26 0,000 0,09785409 0,12671525 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,09785409 0,12664709 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,09785409 0,126579 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,09785409 0,12651098 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,09785409 0,12644304 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,09785409 0,12637517 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,09785409 0,12630737 ! molting cycle process GO:0022404 50 26 0,000 0,09785409 0,12623964 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,09785409 0,12617199 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,09785409 0,12610441 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,09785409 0,1260369 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,09785409 0,12596947 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,09785409 0,1259021 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,09785409 0,12583481 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,09785409 0,12576759 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,09785409 0,12570045 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,09785409 0,12563337 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,09785409 0,12556636 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,09785409 0,12549943 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,09785409 0,12543257 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,09785409 0,12536578 ! blastocyst development GO:0001824 49 26 0,000 0,09785409 0,12529906 ! leukocyte proliferation GO:0070661 52 26 0,000 0,09785409 0,12523241 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,09785409 0,12516583 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,09785409 0,12509933 ! iron ion transport GO:0006826 59 27 0,000 0,10142178 0,1295915 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,10142178 0,12952272 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,10142178 0,129454 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,10142178 0,12938536 ! fat cell differentiation GO:0045444 50 27 0,000 0,10142178 0,1293168 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,10142178 0,1292483 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,10142178 0,12917988 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,10142178 0,12911153 ! autophagy GO:0006914 41 27 0,000 0,10142178 0,12904326 ! male gonad development GO:0008584 44 27 0,000 0,10142178 0,12897505 ! response to toxin GO:0009636 47 27 0,000 0,10142178 0,12890692 ! primary neural tube formation GO:0014020 51 27 0,000 0,10142178 0,12883886 ! base-excision repair GO:0006284 41 27 0,000 0,10142178 0,12877087 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,10142178 0,12870295 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,10142178 0,12863511 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,10142178 0,12856733 ! glutathione metabolic process GO:0006749 39 27 0,000 0,10142178 0,12849963 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,10142178 0,128432 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,10142178 0,12836444 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,10142178 0,12829695 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,10497548 0,13272254 ! circadian rhythm GO:0007623 50 28 0,000 0,10497548 0,13265283 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,10497548 0,1325832 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,10497548 0,13251364 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,10497548 0,13244415 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,10497548 0,13237474 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,10497548 0,13230539 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,10497548 0,13223612 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,10497548 0,13216693 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,10497548 0,1320978 ! synaptogenesis GO:0007416 42 28 0,000 0,10497548 0,13202875 ! lipid oxidation GO:0034440 43 28 0,000 0,10497548 0,13195977 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,10497548 0,13189086 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,10497548 0,13182202 ! translational initiation GO:0006413 65 29 0,000 0,10851524 0,13619597 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,10851524 0,13612496 ! regulation of pH GO:0006885 43 29 0,000 0,10851524 0,13605402 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,10851524 0,13598316 ! catechol metabolic process GO:0009712 54 29 0,000 0,10851524 0,13591237 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,10851524 0,13584166 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,10851524 0,13577102 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,10851524 0,13570045 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,10851524 0,13562996 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,10851524 0,13555954 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,10851524 0,13548919 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,10851524 0,13541891 ! detection of light stimulus GO:0009583 38 29 0,000 0,10851524 0,13534871 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,10851524 0,13527858 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,10851524 0,13520853 ! tissue homeostasis GO:0001894 48 29 0,000 0,10851524 0,13513854 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,10851524 0,13506863 ! phenol metabolic process GO:0018958 55 30 0,000 0,11204112 0,13938518 ! zinc ion transport GO:0006829 45 30 0,000 0,11204112 0,13931314 ! membrane docking GO:0022406 61 30 0,000 0,11204112 0,13924118 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,11204112 0,1391693 ! regulation of innate immune response GO:0045088 51 30 0,000 0,11204112 0,13909749 ! acute-phase response GO:0006953 49 30 0,000 0,11204112 0,13902575 ! myofibril assembly GO:0030239 47 30 0,000 0,11204112 0,13895409 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,11204112 0,1388825 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,11204112 0,13881099 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,11204112 0,13873954 ! phospholipid transport GO:0015914 51 30 0,000 0,11204112 0,13866818 ! ensheathment of neurons GO:0007272 57 30 0,000 0,11204112 0,13859688 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,11204112 0,13852566 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,11204112 0,13845451 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,11204112 0,13838344 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,11204112 0,13831243 ! eye morphogenesis GO:0048592 60 30 0,000 0,11204112 0,1382415 ! response to heat GO:0009408 50 30 0,000 0,11204112 0,13817065 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,11555317 0,14242876 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,11555317 0,14235583 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,11555317 0,14228297 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,11555317 0,14221019 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,11555317 0,14213749 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,11555317 0,14206486 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,11555317 0,1419923 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,11555317 0,14191982 ! ovulation cycle process GO:0022602 49 31 0,000 0,11555317 0,14184741 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,11555317 0,14177508 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,11555317 0,14170282 ! peptide transport GO:0015833 55 31 0,000 0,11555317 0,14163063 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,11555317 0,14155852 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,11555317 0,14148648 ! mesoderm formation GO:0001707 69 31 0,000 0,11555317 0,14141451 ! natural killer cell activation GO:0030101 45 31 0,000 0,11555317 0,14134262 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,11555317 0,1412708 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,11555317 0,14119905 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,11555317 0,14112738 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,11555317 0,14105577 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,11905145 0,14525243 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,11905145 0,14517881 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,11905145 0,14510526 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,11905145 0,14503179 ! cholesterol transport GO:0030301 56 32 0,000 0,11905145 0,14495839 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,11905145 0,14488507 ! spliceosome assembly GO:0000245 67 32 0,000 0,11905145 0,14481182 ! spindle organization GO:0007051 46 32 0,000 0,11905145 0,14473865 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,11905145 0,14466555 ! metanephros development GO:0001656 74 32 0,000 0,11905145 0,14459252 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,11905145 0,14451957 ! response to ionizing radiation GO:0010212 65 32 0,000 0,11905145 0,14444669 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,11905145 0,14437388 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,11905145 0,14430115 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,11905145 0,14422849 ! muscle cell development GO:0055001 49 32 0,000 0,11905145 0,14415591 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,11905145 0,14408339 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,11905145 0,14401095 ! ovulation cycle GO:0042698 51 32 0,000 0,11905145 0,14393859 ! peripheral nervous system development GO:0007422 64 32 0,000 0,11905145 0,14386629 ! BMP signaling pathway GO:0030509 64 32 0,000 0,11905145 0,14379407 ! hindbrain development GO:0030902 61 32 0,000 0,11905145 0,14372192 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,11905145 0,14364984 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,11905145 0,14357784 ! gene silencing GO:0016458 65 32 0,000 0,11905145 0,1435059 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,12253601 0,14763226 ! post-embryonic development GO:0009791 69 33 0,000 0,12253601 0,14755837 ! protein targeting to membrane GO:0006612 68 33 0,000 0,12253601 0,14748456 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,12253601 0,14741081 ! ceramide metabolic process GO:0006672 64 33 0,000 0,12253601 0,14733715 ! formation of primary germ layer GO:0001704 72 33 0,000 0,12253601 0,14726355 ! cell fate specification GO:0001708 52 33 0,000 0,12253601 0,14719003 ! sterol transport GO:0015918 57 33 0,000 0,12253601 0,14711658 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,12253601 0,14704321 ! adult locomotory behavior GO:0008344 59 33 0,000 0,12253601 0,1469699 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,12253601 0,14689668 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,12253601 0,14682352 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,12600689 0,15090721 ! glial cell differentiation GO:0010001 63 34 0,000 0,12600689 0,15083213 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,12600689 0,15075713 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,12600689 0,1506822 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,12600689 0,15060735 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,12600689 0,15053257 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,12600689 0,15045786 ! mismatch repair GO:0006298 46 34 0,000 0,12600689 0,15038323 ! spermatid development GO:0007286 63 34 0,000 0,12600689 0,15030867 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,12600689 0,15023419 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,12600689 0,15015978 ! regulation of muscle development GO:0048634 70 35 0,000 0,12946417 0,15420336 ! negative regulation of secretion GO:0051048 63 35 0,000 0,12946417 0,15412706 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,12946417 0,15405083 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,12946417 0,15397469 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,12946417 0,15389861 ! odontogenesis GO:0042476 66 35 0,000 0,12946417 0,15382261 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,12946417 0,15374669 ! female gonad development GO:0008585 58 35 0,000 0,12946417 0,15367084 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,12946417 0,15359506 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,12946417 0,15351936 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,12946417 0,15344374 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,12946417 0,15336819 ! cytokine production GO:0001816 59 35 0,000 0,12946417 0,15329271 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,12946417 0,15321731 ! neural tube formation GO:0001841 67 35 0,000 0,12946417 0,15314198 ! vesicle localization GO:0051648 64 35 0,000 0,12946417 0,15306673 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,13290788 0,15706108 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,13290788 0,15698398 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,13290788 0,15690695 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,13290788 0,15683 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,13290788 0,15675312 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,13290788 0,15667632 ! positive regulation of cell development GO:0010720 80 36 0,000 0,13290788 0,15659959 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,13290788 0,15652294 ! regulation of proteolysis GO:0030162 72 36 0,000 0,13290788 0,15644636 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,13290788 0,15636986 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,13290788 0,15629343 ! aerobic respiration GO:0009060 55 36 0,000 0,13290788 0,15621708 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,13290788 0,1561408 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,13290788 0,1560646 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,13290788 0,15598847 ! RNA export from nucleus GO:0006405 56 37 0,000 0,13633808 0,15993634 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,13633808 0,1598584 ! meiosis I GO:0007127 65 37 0,000 0,13633808 0,15978053 ! sister chromatid segregation GO:0000819 58 37 0,000 0,13633808 0,15970274 ! actomyosin structure organization GO:0031032 62 37 0,000 0,13633808 0,15962503 ! organic anion transport GO:0015711 68 37 0,000 0,13633808 0,15954739 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,13633808 0,15946983 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,13633808 0,15939234 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,13633808 0,15931493 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,13633808 0,15923759 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,13633808 0,15916033 ! glycogen metabolic process GO:0005977 61 37 0,000 0,13633808 0,15908314 ! pigment metabolic process GO:0042440 80 37 0,000 0,13633808 0,15900603 ! spermatid differentiation GO:0048515 66 37 0,000 0,13633808 0,15892899 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,13975483 0,16283299 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,13975483 0,16275418 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,13975483 0,16267544 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,13975483 0,16259677 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,13975483 0,16251819 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,13975483 0,16243967 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,13975483 0,16236124 ! lipid homeostasis GO:0055088 67 38 0,000 0,13975483 0,16228288 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,13975483 0,1622046 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,13975483 0,16212639 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,13975483 0,16204825 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,13975483 0,1619702 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,13975483 0,16189221 ! glucan metabolic process GO:0044042 62 38 0,000 0,13975483 0,16181431 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,14315818 0,16567512 ! mammary gland development GO:0030879 86 39 0,000 0,14315818 0,16559547 ! learning GO:0007612 77 39 0,000 0,14315818 0,16551589 ! ear morphogenesis GO:0042471 60 39 0,000 0,14315818 0,16543639 ! organic ether metabolic process GO:0018904 55 39 0,000 0,14315818 0,16535697 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,14315818 0,16527763 ! ion transmembrane transport GO:0034220 66 39 0,000 0,14315818 0,16519836 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,14315818 0,16511916 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,14315818 0,16504004 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,14315818 0,164961 ! RNA modification GO:0009451 57 39 0,000 0,14315818 0,16488203 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,14315818 0,16480314 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,14654817 0,16862501 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,14654817 0,1685444 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,14654817 0,16846388 ! feeding behavior GO:0007631 59 40 0,000 0,14654817 0,16838342 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,14654817 0,16830305 ! maintenance of protein location GO:0045185 91 40 0,000 0,14654817 0,16822275 ! cytokinesis GO:0000910 72 40 0,000 0,14654817 0,16814253 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,14992486 0,1719348 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,14992486 0,17185289 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,14992486 0,17177105 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,14992486 0,1716893 ! gliogenesis GO:0042063 88 41 0,000 0,14992486 0,17160762 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,14992486 0,17152602 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,14992486 0,17144449 ! T cell differentiation GO:0030217 81 41 0,000 0,14992486 0,17136305 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,14992486 0,17128168 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,14992486 0,17120039 ! female gamete generation GO:0007292 61 41 0,000 0,14992486 0,17111917 ! polyol metabolic process GO:0019751 66 41 0,000 0,14992486 0,17103803 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,14992486 0,17095697 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,1532883 0,17470945 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,1532883 0,17462673 ! regulation of tube size GO:0035150 71 42 0,000 0,1532883 0,17454409 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,1532883 0,17446152 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,1532883 0,17437903 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,1532883 0,17429663 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,1532883 0,17421429 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,1532883 0,17413204 ! neuron migration GO:0001764 79 42 0,000 0,1532883 0,17404986 ! regulation of protein secretion GO:0050708 71 42 0,000 0,1532883 0,17396776 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,15663855 0,17768616 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,15663855 0,17760243 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,15663855 0,17751877 ! neural tube development GO:0021915 77 43 0,000 0,15663855 0,17743519 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,15663855 0,1773517 ! striated muscle contraction GO:0006941 77 43 0,000 0,15663855 0,17726828 ! phagocytosis GO:0006909 90 43 0,000 0,15663855 0,17718493 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,15663855 0,17710167 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,15997565 0,18078977 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,15997565 0,18070489 ! male sex differentiation GO:0046661 76 44 0,000 0,15997565 0,18062009 ! double-strand break repair GO:0006302 81 44 0,000 0,15997565 0,18053538 ! biopolymer methylation GO:0043414 84 44 0,000 0,15997565 0,18045074 ! B cell differentiation GO:0030183 107 44 0,000 0,15997565 0,18036618 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,15997565 0,1802817 ! developmental growth GO:0048589 82 44 0,000 0,15997565 0,1801973 ! maintenance of location in cell GO:0051651 97 44 0,000 0,15997565 0,18011297 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,16329966 0,1837694 ! glycolysis GO:0006096 65 45 0,000 0,16329966 0,18368349 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,16329966 0,18359766 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,16329966 0,1835119 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,16329966 0,18342623 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,16329966 0,18334064 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,16329966 0,18325512 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,16329966 0,18316969 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,16329966 0,18308434 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,16329966 0,18299906 ! cell growth GO:0016049 84 45 0,000 0,16329966 0,18291387 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,16661063 0,18653568 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,16661063 0,18644892 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,16661063 0,18636224 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,16661063 0,18627564 ! response to calcium ion GO:0051592 81 47 0,000 0,1699086 0,18987464 ! endosome transport GO:0016197 108 47 0,000 0,1699086 0,18978649 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,1699086 0,18969842 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,1699086 0,18961043 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,1699086 0,18952253 ! methylation GO:0032259 90 47 0,000 0,1699086 0,1894347 ! protein homooligomerization GO:0051260 76 47 0,000 0,1699086 0,18934696 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,17319363 0,19291846 ! mitochondrial transport GO:0006839 82 48 0,000 0,17319363 0,19282919 ! cellular component disassembly GO:0022411 86 48 0,000 0,17319363 0,19274 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,17319363 0,19265089 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,17319363 0,19256186 ! activation of caspase activity GO:0006919 84 48 0,000 0,17319363 0,19247292 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,17319363 0,19238406 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,17319363 0,19229528 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,17646577 0,19583793 ! regulation of action potential GO:0001508 95 49 0,000 0,17646577 0,19574764 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,17646577 0,19565744 ! regulation of ion transport GO:0043269 77 49 0,000 0,17646577 0,19556732 ! peptide metabolic process GO:0006518 76 49 0,000 0,17646577 0,19547727 ! response to temperature stimulus GO:0009266 76 49 0,000 0,17646577 0,19538732 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,17646577 0,19529744 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,17646577 0,19520765 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,17646577 0,19511794 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,17646577 0,19502831 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,17646577 0,19493877 ! neuromuscular process GO:0050905 99 50 0,000 0,17972507 0,19844815 ! regulation of ossification GO:0030278 117 50 0,000 0,17972507 0,19835712 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,17972507 0,19826617 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,17972507 0,1981753 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,18297157 0,20166267 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,18297157 0,20157033 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,18297157 0,20147808 ! excretion GO:0007588 83 51 0,000 0,18297157 0,20138591 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,18297157 0,20129383 ! chromatin remodeling GO:0006338 109 51 0,000 0,18297157 0,20120183 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,18297157 0,20110992 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,18297157 0,20101809 ! vesicle organization GO:0016050 107 51 0,000 0,18297157 0,20092634 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,18297157 0,20083467 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,18620534 0,20429095 ! synapse organization GO:0050808 85 52 0,000 0,18620534 0,20419783 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,18942641 0,20763551 ! RNA catabolic process GO:0006401 93 53 0,000 0,18942641 0,20754096 ! regulation of translational initiation GO:0006446 82 53 0,000 0,18942641 0,20744649 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,18942641 0,20735211 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,18942641 0,20725782 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,18942641 0,20716361 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,18942641 0,20706949 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,18942641 0,20697545 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,19263484 0,21038558 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,19263484 0,21029012 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,19263484 0,21019475 ! cell recognition GO:0008037 85 54 0,000 0,19263484 0,21009947 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,19263484 0,21000427 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,19263484 0,20990916 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,19263484 0,20981414 ! chloride transport GO:0006821 90 55 0,000 0,19583068 0,21319847 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,19583068 0,21310204 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,19583068 0,2130057 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,19583068 0,21290945 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,19583068 0,21281329 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,19583068 0,21271721 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,19583068 0,21262122 ! aging GO:0007568 103 55 0,000 0,19583068 0,21252531 ! gastrulation GO:0007369 112 55 0,000 0,19583068 0,21242949 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,19583068 0,21233376 ! RNA elongation GO:0006354 79 55 0,000 0,19583068 0,21223812 ! nuclear export GO:0051168 97 55 0,000 0,19583068 0,21214256 ! regulation of actin filament length GO:0030832 105 56 0,000 0,19901397 0,21549398 ! sensory perception of smell GO:0007608 80 56 0,000 0,19901397 0,21539704 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,19901397 0,21530019 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,19901397 0,21520342 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,19901397 0,21510675 ! proton transport GO:0015992 94 56 0,000 0,19901397 0,21501016 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,19901397 0,21491365 ! muscle fiber development GO:0048747 112 57 0,000 0,20218477 0,21823982 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,20218477 0,21814195 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,20218477 0,21804418 ! maintenance of location GO:0051235 118 57 0,000 0,20218477 0,21794649 ! hydrogen transport GO:0006818 97 58 0,000 0,20534312 0,22125192 ! regulation of endocytosis GO:0030100 91 58 0,000 0,20534312 0,22115289 ! adult behavior GO:0030534 99 58 0,000 0,20534312 0,22105394 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,20534312 0,22095508 ! positive regulation of secretion GO:0051047 95 59 0,000 0,20848907 0,22423992 ! regulation of cellular component size GO:0032535 109 59 0,000 0,20848907 0,22413973 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,20848907 0,22403962 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,20848907 0,2239396 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,20848907 0,22383967 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,20848907 0,22373983 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,21162267 0,22700141 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,21162267 0,22690025 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,21162267 0,22679918 ! camera-type eye development GO:0043010 116 60 0,000 0,21162267 0,2266982 ! kidney development GO:0001822 122 60 0,000 0,21162267 0,22659731 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,21474397 0,22983719 ! tRNA processing GO:0008033 89 61 0,000 0,21474397 0,22973499 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,21474397 0,22963289 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,21785302 0,232854 ! gonad development GO:0008406 98 62 0,000 0,21785302 0,23275061 ! regulation of mitosis GO:0007088 105 63 0,000 0,22094986 0,23595444 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,22094986 0,23584976 ! detection of external stimulus GO:0009581 91 63 0,000 0,22094986 0,23574517 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,22094986 0,23564067 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,22094986 0,23553627 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,22403454 0,23871882 ! cell redox homeostasis GO:0045454 102 64 0,000 0,22403454 0,23861315 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,22403454 0,23850757 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,22403454 0,23840208 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,22403454 0,23829668 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,22710711 0,24145811 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,22710711 0,24135146 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,22710711 0,2412449 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,22710711 0,24113844 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,23016761 0,24428022 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,23016761 0,24417252 ! extracellular matrix organization GO:0030198 133 66 0,000 0,23016761 0,2440649 ! secondary metabolic process GO:0019748 116 66 0,000 0,23016761 0,24395739 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,2332161 0,24707967 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,2332161 0,24697092 ! chromosome segregation GO:0007059 113 67 0,000 0,2332161 0,24686226 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,2332161 0,24675371 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,2332161 0,24664524 ! hexose catabolic process GO:0019320 104 67 0,000 0,2332161 0,24653687 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,2332161 0,2464286 ! activation of immune response GO:0002253 105 67 0,000 0,2332161 0,24632042 ! amino acid transport GO:0006865 125 68 0,000 0,23625261 0,24941807 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,23625261 0,24930868 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,23625261 0,24919938 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,23625261 0,24909018 ! regulation of lipase activity GO:0060191 130 68 0,000 0,23625261 0,24898107 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,23625261 0,24887206 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,23625261 0,24876314 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,2392772 0,25183769 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,2392772 0,25172757 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,2392772 0,25161755 ! urogenital system development GO:0001655 137 69 0,000 0,2392772 0,25150762 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,2392772 0,25139779 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,2392772 0,25128806 ! antigen processing and presentation GO:0019882 104 69 0,000 0,2392772 0,25117842 ! appendage morphogenesis GO:0035107 135 70 0,000 0,24228992 0,25423006 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,2452908 0,25726663 ! reproductive structure development GO:0048608 113 71 0,000 0,2452908 0,25715454 ! appendage development GO:0048736 136 71 0,000 0,2452908 0,25704253 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,2452908 0,25693063 ! B cell activation GO:0042113 160 71 0,000 0,2452908 0,25681882 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,2452908 0,25670712 ! regulation of immune effector process GO:0002697 137 71 0,000 0,2452908 0,2565955 ! acute inflammatory response GO:0002526 113 72 0,000 0,24827989 0,25960949 ! regulation of caspase activity GO:0043281 122 72 0,000 0,24827989 0,25949671 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,24827989 0,25938403 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,24827989 0,25927145 ! learning or memory GO:0007611 147 73 0,000 0,25125725 0,26226679 ! regulation of blood pressure GO:0008217 125 73 0,000 0,25125725 0,26215306 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,25125725 0,26203942 ! axon guidance GO:0007411 139 73 0,000 0,25125725 0,26192589 ! fertilization GO:0009566 90 73 0,000 0,25125725 0,26181245 ! transition metal ion transport GO:0000041 126 74 0,000 0,25422291 0,26478802 ! neurotransmitter transport GO:0006836 123 74 0,000 0,25422291 0,26467345 ! meiosis GO:0007126 121 74 0,000 0,25422291 0,26455897 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,25422291 0,26444459 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,25422291 0,26433031 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,25422291 0,26421613 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,25422291 0,26410204 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,25717693 0,26705554 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,25717693 0,26694033 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,25717693 0,26682522 ! meiotic cell cycle GO:0051321 122 75 0,000 0,25717693 0,26671021 ! rhythmic process GO:0048511 128 75 0,000 0,25717693 0,2665953 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,25717693 0,26648049 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,26011934 0,26941332 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,26011934 0,26929739 ! defense response to bacterium GO:0042742 89 76 0,000 0,26011934 0,26918156 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,26011934 0,26906584 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,26011934 0,26895021 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,2630502 0,27186373 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,2630502 0,271747 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,2630502 0,27163037 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,26596954 0,27452712 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,26596954 0,27440939 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,26596954 0,27429177 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,26887741 0,27717183 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,26887741 0,27705313 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,26887741 0,27693453 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,26887741 0,27681603 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,26887741 0,27669763 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,26887741 0,27657933 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,27177386 0,27943928 ! response to metal ion GO:0010038 140 80 0,000 0,27177386 0,27931991 ! muscle cell differentiation GO:0042692 159 80 0,000 0,27177386 0,27920065 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,27177386 0,27908148 ! protein import into nucleus GO:0006606 158 80 0,000 0,27177386 0,27896242 ! inorganic anion transport GO:0015698 138 80 0,000 0,27177386 0,27884346 ! T cell activation GO:0042110 168 81 0,000 0,27465893 0,28168346 ! digestion GO:0007586 112 81 0,000 0,27465893 0,28156344 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,27465893 0,28144352 ! nuclear import GO:0051170 161 81 0,000 0,27465893 0,28132371 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,27753267 0,28414622 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,27753267 0,28402535 ! response to drug GO:0042493 143 82 0,000 0,27753267 0,2839046 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,27753267 0,28378394 ! regulation of lyase activity GO:0051339 160 83 0,000 0,28039512 0,28658906 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,28324632 0,28938032 ! regulation of ligase activity GO:0051340 142 84 0,000 0,28324632 0,28925749 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,28324632 0,28913477 ! response to unfolded protein GO:0006986 131 85 0,000 0,28608632 0,29190996 ! nucleosome assembly GO:0006334 122 85 0,000 0,28608632 0,29178622 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,28608632 0,29166258 ! amine biosynthetic process GO:0009309 138 86 0,000 0,28891516 0,2944218 ! response to inorganic substance GO:0010035 153 86 0,000 0,28891516 0,29429715 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,28891516 0,29417261 ! chromatin assembly GO:0031497 124 86 0,000 0,28891516 0,29404817 ! tube morphogenesis GO:0035239 176 86 0,000 0,28891516 0,29392384 ! mitochondrion organization GO:0007005 148 86 0,000 0,28891516 0,29379961 ! alcohol catabolic process GO:0046164 130 86 0,000 0,28891516 0,29367549 ! amine transport GO:0015837 155 86 0,000 0,28891516 0,29355147 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,29173289 0,29628929 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,29173289 0,29616427 ! protein localization in nucleus GO:0034504 176 87 0,000 0,29173289 0,29603936 ! regulation of protein transport GO:0051223 154 87 0,000 0,29173289 0,29591455 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,29453954 0,29863554 ! regulation of neurological system process GO:0031644 148 88 0,000 0,29453954 0,29850974 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,29453954 0,29838405 ! cellular defense response GO:0006968 114 89 0,000 0,29733516 0,30108939 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,29733516 0,30096273 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,3001198 0,30365359 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,3001198 0,30352595 ! sex differentiation GO:0007548 145 90 0,000 0,3001198 0,30339842 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,3001198 0,303271 ! sterol metabolic process GO:0016125 152 91 0,000 0,3028935 0,30594532 ! response to protein stimulus GO:0051789 149 91 0,000 0,3028935 0,30581693 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,3028935 0,30568865 ! nucleosome organization GO:0034728 138 92 0,000 0,30565629 0,3083476 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,30565629 0,30821837 ! vitamin metabolic process GO:0006766 139 92 0,000 0,30565629 0,30808925 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,30840823 0,31073291 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,30840823 0,31060284 ! regulation of membrane potential GO:0042391 164 93 0,000 0,30840823 0,31047288 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,31114935 0,31310135 ! female pregnancy GO:0007565 164 94 0,000 0,31114935 0,31297046 ! transcription initiation GO:0006352 153 94 0,000 0,31114935 0,31283967 ! regulation of T cell activation GO:0050863 158 94 0,000 0,31114935 0,31270899 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,31659931 0,31805342 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,31659931 0,31792068 ! positive regulation of immune response GO:0050778 156 96 0,000 0,31659931 0,31778805 ! detection of stimulus GO:0051606 151 96 0,000 0,31659931 0,31765552 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,31930824 0,32023994 ! protein ubiquitination GO:0016567 217 97 0,000 0,31930824 0,32010651 ! hormone metabolic process GO:0042445 157 97 0,000 0,31930824 0,31997319 ! regulation of protein localization GO:0032880 176 97 0,000 0,31930824 0,31983998 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,32200652 0,32240852 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,32200652 0,32227441 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,32469419 0,3248292 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,32469419 0,32469419