pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1145-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 10 5 2,000 8,49E-07 1,953E-03 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 8,49E-07 9,763E-04 GO:0031272|regulation of pseudopodium assembly, ! ER overload response GO:0006983 7 6 2,000 1,693E-06 1,298E-03 ! macrophage differentiation GO:0030225 10 6 2,000 1,693E-06 9,732E-04 ! regulation of lipid kinase activity GO:0043550 12 7 2,000 2,952E-06 1,358E-03 ! establishment of nucleus localization GO:0040023 13 7 2,000 2,952E-06 1,132E-03 ! nucleus localization GO:0051647 15 9 2,000 7,04E-06 2,313E-03 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 2,000 1,003E-05 2,882E-03 GO:0007520|myoblast fusion, ! regulation of cell projection assembly GO:0060491 20 10 2,000 1,003E-05 2,562E-03 ! filopodium assembly GO:0046847 19 11 2,000 1,374E-05 3,16E-03 ! syncytium formation GO:0006949 15 11 2,000 1,374E-05 2,873E-03 ! microspike assembly GO:0030035 23 12 2,000 1,826E-05 3,5E-03 ! myotube differentiation GO:0014902 21 14 2,000 3,002E-05 5,311E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 3,002E-05 4,932E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 6,644E-05 0,01018717 ! plasma membrane fusion GO:0045026 23 19 2,000 7,864E-05 0,01130479 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 2,000 7,864E-05 0,0106398 ! myeloid leukocyte differentiation GO:0002573 33 21 2,000 1,072E-04 0,01370395 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 1,072E-04 0,01298269 ! regulation of lipid metabolic process GO:0019216 84 56 3,000 1,129E-04 0,01298727 ! protein tetramerization GO:0051262 39 22 2,000 1,238E-04 0,01355728 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 1,419E-04 0,01483446 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 1,616E-04 0,01616454 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 1,616E-04 0,01549102 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 1,948E-04 0,017924 ! positive regulation of glycolysis GO:0045821 11 5 1,000 1,948E-04 0,01723462 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 1,948E-04 0,0165963 ! regulation of respiratory burst GO:0060263 8 5 1,000 1,948E-04 0,01600357 ! regulation of caspase activity GO:0043281 97 65 3,000 2,019E-04 0,01601645 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 2,000 2,063E-04 0,01581771 ! regulation of endopeptidase activity GO:0052548 99 67 3,000 2,271E-04 0,01684845 ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 2,583E-04 0,01856508 ! regulation of helicase activity GO:0051095 11 6 1,000 2,914E-04 0,0203092 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 2,914E-04 0,01971188 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 2,914E-04 0,01914868 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 2,914E-04 0,01861677 ! male sex determination GO:0030238 9 6 1,000 2,914E-04 0,01811361 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 2,914E-04 0,01763694 ! regulation of peptidase activity GO:0052547 106 72 3,000 2,997E-04 0,01767513 ! regulation of microtubule-based process GO:0032886 58 30 2,000 3,181E-04 0,01828865 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 4,068E-04 0,02281876 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 4,068E-04 0,02227545 ! protein heterooligomerization GO:0051291 10 7 1,000 4,068E-04 0,02175742 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 4,068E-04 0,02126293 ! B cell lineage commitment GO:0002326 17 7 1,000 4,068E-04 0,02079042 ! T cell lineage commitment GO:0002360 12 7 1,000 4,068E-04 0,02033846 ! response to tumor cell GO:0002347 12 7 1,000 4,068E-04 0,01990572 ! positive regulation of ATPase activity GO:0032781 10 7 1,000 4,068E-04 0,01949102 ! trophectodermal cell differentiation GO:0001829 8 7 1,000 4,068E-04 0,01909325 ! androgen receptor signaling pathway GO:0030521 54 33 2,000 4,233E-04 0,01947334 ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 4,628E-04 0,02087204 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 4,628E-04 0,02047066 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 5,046E-04 0,02189702 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 5,408E-04 0,02303362 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 5,408E-04 0,02261483 ! middle ear morphogenesis GO:0042474 9 8 1,000 5,408E-04 0,02221099 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 5,408E-04 0,02182132 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 5,408E-04 0,0214451 ! regulation of telomere maintenance GO:0032204 10 8 1,000 5,408E-04 0,02108162 ! regulation of embryonic development GO:0045995 16 8 1,000 5,408E-04 0,02073026 ! regulation of DNA metabolic process GO:0051052 135 85 3,000 5,646E-04 0,02128798 ! cell cycle arrest GO:0007050 150 86 3,000 5,901E-04 0,02189251 ! skeletal muscle tissue development GO:0007519 123 87 3,000 6,165E-04 0,02250745 GO:0060538|skeletal muscle organ development, ! regulation of developmental growth GO:0048638 13 9 1,000 6,933E-04 0,02491508 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 6,933E-04 0,02453177 ! regulation of glycolysis GO:0006110 15 9 1,000 6,933E-04 0,02416008 ! DNA ligation GO:0006266 14 9 1,000 6,933E-04 0,02379948 ! blastocyst formation GO:0001825 12 9 1,000 6,933E-04 0,02344948 ! embryonic placenta development GO:0001892 12 9 1,000 6,933E-04 0,02310964 ! leukocyte differentiation GO:0002521 143 90 3,000 7,006E-04 0,02301993 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 7,496E-04 0,0242824 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 7,925E-04 0,02531673 ! positive regulation of DNA binding GO:0043388 57 41 2,000 8,062E-04 0,02540016 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 8,641E-04 0,02685732 ! response to X-ray GO:0010165 16 10 1,000 8,641E-04 0,02649922 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 8,641E-04 0,02615055 ! embryonic axis specification GO:0000578 12 10 1,000 8,641E-04 0,02581093 ! protein sumoylation GO:0016925 12 10 1,000 8,641E-04 0,02548002 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 8,641E-04 0,02515749 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 8,654E-04 0,02488074 ! positive regulation of binding GO:0051099 59 43 2,000 9,273E-04 0,02633215 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 9,273E-04 0,02601103 ! activation of caspase activity GO:0006919 65 43 2,000 9,273E-04 0,02569764 ! response to insulin stimulus GO:0032868 63 43 2,000 9,273E-04 0,02539172 ! regulation of cell projection organization GO:0031344 83 44 2,000 9,92E-04 0,026843 ! respiratory burst GO:0045730 14 11 1,000 1,053E-03 0,02816364 ! virus-host interaction GO:0019048 17 11 1,000 1,053E-03 0,02783992 ! detection of mechanical stimulus GO:0050982 15 11 1,000 1,053E-03 0,02752355 ! regulation of intracellular pH GO:0051453 17 11 1,000 1,053E-03 0,0272143 ! germ cell migration GO:0008354 18 11 1,000 1,053E-03 0,02691192 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 1,26E-03 0,03184711 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 1,26E-03 0,03150095 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 1,26E-03 0,03116223 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,26E-03 0,03083071 ! response to gamma radiation GO:0010332 20 12 1,000 1,26E-03 0,03050618 ! positive regulation of caspase activity GO:0043280 72 48 2,000 1,279E-03 0,03064412 GO:0010952|positive regulation of peptidase activity, ! regulation of DNA replication GO:0006275 75 48 2,000 1,279E-03 0,0303282 ! regulation of intracellular transport GO:0032386 78 49 2,000 1,358E-03 0,03187438 ! integrin-mediated signaling pathway GO:0007229 81 49 2,000 1,358E-03 0,03155241 ! skeletal muscle fiber development GO:0048741 73 50 2,000 1,44E-03 0,03312465 ! membrane fusion GO:0006944 80 50 2,000 1,44E-03 0,03279668 ! lipid modification GO:0030258 73 50 2,000 1,44E-03 0,03247514 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,485E-03 0,03315647 ! intermediate filament cytoskeleton organization GO:0045104 23 13 1,000 1,485E-03 0,03283766 ! negative regulation of protein import into nucleus GO:0042308 25 13 1,000 1,485E-03 0,03252492 ! regulation of cellular pH GO:0030641 20 13 1,000 1,485E-03 0,03221808 ! regulation of calcium-mediated signaling GO:0050848 18 13 1,000 1,485E-03 0,03191698 ! muscle fiber development GO:0048747 74 51 2,000 1,525E-03 0,03248389 ! establishment of organelle localization GO:0051656 85 52 2,000 1,614E-03 0,03404743 ! cell projection assembly GO:0030031 76 53 2,000 1,705E-03 0,03564808 ! superoxide anion generation GO:0042554 18 14 1,000 1,727E-03 0,03579094 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,727E-03 0,03547138 ! cellular response to starvation GO:0009267 21 14 1,000 1,727E-03 0,03515748 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 1,727E-03 0,03484908 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 1,727E-03 0,03454604 ! G1/S transition checkpoint GO:0031575 33 14 1,000 1,727E-03 0,03424823 ! intermediate filament-based process GO:0045103 24 14 1,000 1,727E-03 0,03395551 ! axon cargo transport GO:0008088 27 14 1,000 1,727E-03 0,03366775 ! regulation of ATPase activity GO:0043462 18 14 1,000 1,727E-03 0,03338483 ! regulation of protein complex assembly GO:0043254 81 54 2,000 1,799E-03 0,03448923 ! lipid phosphorylation GO:0046834 23 15 1,000 1,987E-03 0,03777486 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 1,987E-03 0,03746523 ! regulation of survival gene product expression GO:0045884 20 15 1,000 1,987E-03 0,03716064 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 1,987E-03 0,03686095 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 1,987E-03 0,03656607 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 1,987E-03 0,03627586 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 1,987E-03 0,03599022 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 2,102E-03 0,03777861 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 2,21E-03 0,03940442 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 2,265E-03 0,04006651 ! protein amino acid acetylation GO:0006473 28 16 1,000 2,265E-03 0,03976066 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 2,265E-03 0,03945944 ! myeloid cell differentiation GO:0030099 85 59 2,000 2,321E-03 0,04013845 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 2,559E-03 0,04392611 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 2,559E-03 0,04360073 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 2,559E-03 0,04328014 ! peptidyl-serine modification GO:0018209 27 17 1,000 2,559E-03 0,04296422 ! negative regulation of cell growth GO:0030308 106 62 2,000 2,675E-03 0,04457521 ! organelle localization GO:0051640 96 62 2,000 2,675E-03 0,04425453 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 2,799E-03 0,04598841 ! positive regulation of DNA replication GO:0045740 29 18 1,000 2,871E-03 0,04682809 ! axis specification GO:0009798 26 18 1,000 2,871E-03 0,04649831 ! somitogenesis GO:0001756 24 18 1,000 2,871E-03 0,04617315 ! cellular response to nutrient levels GO:0031669 27 18 1,000 2,871E-03 0,0458525 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 2,871E-03 0,04553628 ! negative regulation of cell size GO:0045792 108 64 2,000 2,928E-03 0,04611992 ! protein oligomerization GO:0051259 100 65 2,000 3,059E-03 0,04786972 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 3,199E-03 0,04971808 GO:0010675|regulation of cellular carbohydrate metabolic process, ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 3,199E-03 0,0493844 ! response to alkaloid GO:0043279 32 19 1,000 3,199E-03 0,04905517 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 3,199E-03 0,0487303 ! apoptotic nuclear changes GO:0030262 24 19 1,000 3,199E-03 0,04840971 ! response to starvation GO:0042594 30 19 1,000 3,199E-03 0,04809331 ! sex determination GO:0007530 29 19 1,000 3,199E-03 0,04778101 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 3,199E-03 0,04747275 ! microtubule-based transport GO:0010970 37 20 1,000 3,544E-03 0,05225829 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 3,544E-03 0,05192544 ! gluconeogenesis GO:0006094 25 21 1,000 3,906E-03 0,0568637 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 3,906E-03 0,05650607 ! protein amino acid acylation GO:0043543 37 21 1,000 3,906E-03 0,05615291 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 3,906E-03 0,05580413 ! cell aging GO:0007569 32 21 1,000 3,906E-03 0,05545966 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 3,906E-03 0,05511942 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 3,906E-03 0,05478332 ! muscle cell differentiation GO:0042692 104 71 2,000 3,928E-03 0,05474722 ! mitochondrion organization GO:0007005 104 73 2,000 4,247E-03 0,05884103 ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 4,285E-03 0,05900863 ! vasculogenesis GO:0001570 33 22 1,000 4,285E-03 0,05865739 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 4,285E-03 0,0583103 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 4,285E-03 0,0579673 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 4,285E-03 0,05762831 ! blastocyst development GO:0001824 37 22 1,000 4,285E-03 0,05729326 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 4,412E-03 0,05865878 ! negative regulation of growth GO:0045926 123 75 2,000 4,581E-03 0,06055868 ! embryonic pattern specification GO:0009880 31 23 1,000 4,679E-03 0,06149644 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 4,679E-03 0,06114703 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 4,679E-03 0,06080157 ! negative regulation of DNA replication GO:0008156 35 23 1,000 4,679E-03 0,06045999 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 4,679E-03 0,06012222 ! interaction with host GO:0051701 37 23 1,000 4,679E-03 0,05978821 ! regulation of protein transport GO:0051223 114 76 2,000 4,755E-03 0,06041652 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 119 77 2,000 4,932E-03 0,06232182 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 5,09E-03 0,06396957 ! pyruvate metabolic process GO:0006090 29 24 1,000 5,09E-03 0,06362191 ! superoxide metabolic process GO:0006801 32 24 1,000 5,09E-03 0,06327801 ! mitochondrial membrane organization GO:0007006 39 24 1,000 5,09E-03 0,0629378 ! negative regulation of cell development GO:0010721 56 24 1,000 5,09E-03 0,06260124 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 5,09E-03 0,06226825 ! iron ion homeostasis GO:0055072 39 25 1,000 5,516E-03 0,06713102 ! regulation of chromosome organization GO:0033044 35 25 1,000 5,516E-03 0,0667777 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 5,516E-03 0,06642807 ! regulation of pH GO:0006885 36 26 1,000 5,959E-03 0,07138298 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 1,000 5,959E-03 0,07101312 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 6,282E-03 0,0744818 ! response to ionizing radiation GO:0010212 47 27 1,000 6,417E-03 0,07568925 ! negative regulation of protein transport GO:0051224 49 27 1,000 6,417E-03 0,07530308 ! regulation of protein localization GO:0032880 132 85 2,000 6,492E-03 0,07578985 ! positive regulation of catabolic process GO:0009896 40 28 1,000 6,891E-03 0,08004567 ! placenta development GO:0001890 37 28 1,000 6,891E-03 0,07964343 ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 6,922E-03 0,07960658 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 7,38E-03 0,08444836 ! hexose biosynthetic process GO:0019319 35 29 1,000 7,38E-03 0,0840303 ! protein modification by small protein conjugation GO:0032446 140 90 2,000 7,6E-03 0,08610443 ! regulation of cytoskeleton organization GO:0051493 154 93 2,000 8,315E-03 0,09374642 ! DNA damage checkpoint GO:0000077 53 31 1,000 8,404E-03 0,09428911 ! segmentation GO:0035282 41 31 1,000 8,404E-03 0,09383139 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 8,404E-03 0,0933781 ! response to mechanical stimulus GO:0009612 43 31 1,000 8,404E-03 0,09292917 ! regulation of binding GO:0051098 151 95 2,000 8,813E-03 0,0969854 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 8,939E-03 0,0978985 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 8,939E-03 0,09743453 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 8,939E-03 0,09697493 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 8,939E-03 0,09651965 ! in utero embryonic development GO:0001701 147 96 2,000 9,069E-03 0,09746536 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 9,069E-03 0,09701204 ! protein modification by small protein conjugation or removal GO:0070647 148 96 2,000 9,069E-03 0,09656291 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 9,488E-03 0,10056329 ! ear morphogenesis GO:0042471 42 33 1,000 9,488E-03 0,10010199 ! carbohydrate homeostasis GO:0033500 39 33 1,000 9,488E-03 0,09964491 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 1,000 9,488E-03 0,09919198 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 9,488E-03 0,09874314 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,010052 0,10414232 ! DNA integrity checkpoint GO:0031570 57 34 1,000 0,010052 0,10367531 ! glycogen metabolic process GO:0005977 48 35 1,000 0,01063063 0,10915378 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01122368 0,11473099 GO:0090047|positive regulation of transcription regulator activity, ! tissue remodeling GO:0048771 62 36 1,000 0,01122368 0,11422333 ! glucan metabolic process GO:0044042 49 36 1,000 0,01122368 0,11372015 GO:0006073|cellular glucan metabolic process, ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,01245252 0,12561752 ! pigmentation GO:0043473 74 38 1,000 0,01245252 0,12506897 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,01308803 0,13088029 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,01373742 0,13677951 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 1,000 0,01373742 0,13618995 ! T cell differentiation GO:0030217 65 40 1,000 0,01373742 0,13560544 ! double-strand break repair GO:0006302 67 40 1,000 0,01373742 0,13502593 ! B cell differentiation GO:0030183 62 40 1,000 0,01373742 0,13445135 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,01373742 0,13388164 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,01440056 0,13975228 ! mitochondrial transport GO:0006839 60 42 1,000 0,01507732 0,14570518 ! cellular component disassembly GO:0022411 64 42 1,000 0,01507732 0,14509553 ! regulation of cell shape GO:0008360 78 42 1,000 0,01507732 0,14449097 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,01647116 0,15719362 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,01718798 0,16335683 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,0179179 0,16959327 ! histone modification GO:0016570 68 46 1,000 0,0179179 0,16889822 ! response to UV GO:0009411 75 46 1,000 0,0179179 0,16820884 ! covalent chromatin modification GO:0016569 75 47 1,000 0,01866078 0,17447075 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,01866078 0,17376439 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,01941651 0,18007248 ! heart morphogenesis GO:0003007 65 48 1,000 0,01941651 0,1793493 ! nuclear export GO:0051168 69 48 1,000 0,01941651 0,1786319 ! ear development GO:0043583 72 50 1,000 0,02096598 0,19211858 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,02096598 0,19135621 ! positive regulation of growth GO:0045927 67 50 1,000 0,02096598 0,19059986 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 0,02175948 0,19703467 ! positive regulation of cell migration GO:0030335 92 51 1,000 0,02175948 0,19626198 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02211298 0,19867134 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02211298 0,19789829 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02211298 0,19713125 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02211298 0,19637012 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02211298 0,19561485 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02211298 0,19486537 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02211298 0,19412161 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02211298 0,1933835 ! sleep GO:0030431 11 5 0,000 0,02211298 0,19265099 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02211298 0,19192401 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02211298 0,19120249 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02211298 0,19048637 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02211298 0,1897756 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02211298 0,18907012 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02211298 0,18836986 ! tongue development GO:0043586 6 5 0,000 0,02211298 0,18767477 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02211298 0,18698479 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02211298 0,18629986 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02211298 0,18561993 ! cobalt ion transport GO:0006824 9 5 0,000 0,02211298 0,18494495 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02211298 0,18427486 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02211298 0,18360961 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02211298 0,18294914 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02211298 0,18229341 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02211298 0,18164236 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02211298 0,18099595 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02211298 0,18035412 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02211298 0,17971683 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02211298 0,17908402 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02211298 0,17845566 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02211298 0,17783168 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02211298 0,17721206 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02211298 0,17659674 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02211298 0,17598568 ! malate metabolic process GO:0006108 7 5 0,000 0,02211298 0,17537883 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02211298 0,17477616 ! behavioral response to pain GO:0048266 7 5 0,000 0,02211298 0,17417761 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02211298 0,17358315 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02211298 0,17299273 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02211298 0,17240631 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02211298 0,17182386 ! mating behavior GO:0007617 6 5 0,000 0,02211298 0,17124533 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02211298 0,17067068 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02211298 0,17009987 ! rhythmic behavior GO:0007622 12 5 0,000 0,02211298 0,16953287 ! copulation GO:0007620 7 5 0,000 0,02211298 0,16896964 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02211298 0,16841014 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02211298 0,16785433 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02211298 0,16730218 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02211298 0,16675365 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02211298 0,1662087 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02211298 0,1656673 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02211298 0,16512942 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02211298 0,16459502 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02211298 0,16406407 ! response to protozoan GO:0001562 9 5 0,000 0,02211298 0,16353653 ! lymph vessel development GO:0001945 7 5 0,000 0,02211298 0,16301238 ! endochondral ossification GO:0001958 12 5 0,000 0,02211298 0,16249157 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02211298 0,16197408 ! parathyroid gland development GO:0060017 8 5 0,000 0,02211298 0,16145988 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02211298 0,16094893 ! anagen GO:0042640 6 5 0,000 0,02211298 0,1604412 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02211298 0,15993667 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02211298 0,1594353 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02211298 0,15893707 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02211298 0,15844194 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02211298 0,15794988 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02211298 0,15746087 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02211298 0,15697488 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02211298 0,15649188 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02211298 0,15601185 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02211298 0,15553475 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02211298 0,15506055 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02211298 0,15458925 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02211298 0,15412079 ! ovulation GO:0030728 6 5 0,000 0,02211298 0,15365517 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02211298 0,15319235 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02211298 0,15273232 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,02211298 0,15227504 ! response to pH GO:0009268 9 5 0,000 0,02211298 0,15182048 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02211298 0,15136864 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02211298 0,15091947 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02211298 0,15047296 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02211298 0,15002909 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02211298 0,14958783 ! polyol catabolic process GO:0046174 7 5 0,000 0,02211298 0,14914915 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02211298 0,14871305 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02211298 0,14827948 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02211298 0,14784844 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02211298 0,14741989 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02211298 0,14699382 ! urea metabolic process GO:0019627 6 5 0,000 0,02211298 0,14657021 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02211298 0,14614903 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02211298 0,14573026 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02211298 0,14531389 ! neutrophil activation GO:0042119 5 5 0,000 0,02211298 0,14489989 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02211298 0,14448824 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02211298 0,14407893 ! response to food GO:0032094 5 5 0,000 0,02211298 0,14367193 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02211298 0,14326722 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02211298 0,14286478 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02211298 0,1424646 ! forebrain neuron development GO:0021884 7 5 0,000 0,02211298 0,14206665 ! melanosome organization GO:0032438 7 5 0,000 0,02211298 0,14167092 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02211298 0,14127739 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02211298 0,14088604 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02211298 0,14049686 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02211298 0,14010981 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02211298 0,1397249 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02211298 0,13934209 ! nucleoside transport GO:0015858 6 5 0,000 0,02211298 0,13896137 ! nucleoside salvage GO:0043174 7 5 0,000 0,02211298 0,13858273 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02211298 0,13820615 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02211298 0,1378316 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02211298 0,13745909 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02211298 0,13708858 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02211298 0,13672006 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02211298 0,13635352 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02211298 0,13598894 ! depyrimidination GO:0045008 8 5 0,000 0,02211298 0,1356263 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02211298 0,13526559 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02211298 0,1349068 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02211298 0,1345499 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02211298 0,13419489 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02211298 0,13384174 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02211298 0,13349045 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02211298 0,133141 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02211298 0,13279337 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02211298 0,13244756 ! monocyte differentiation GO:0030224 8 5 0,000 0,02211298 0,13210354 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02211298 0,1317613 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02211298 0,13142083 ! centrosome duplication GO:0051298 5 5 0,000 0,02211298 0,13108212 ! response to UV-C GO:0010225 6 5 0,000 0,02211298 0,13074515 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02211298 0,1304099 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02211298 0,13007637 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02211298 0,12974455 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02211298 0,12941441 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02211298 0,12908594 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02211298 0,12875914 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02211298 0,12843399 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02211298 0,12811048 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02211298 0,1277886 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02211298 0,12746833 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02211298 0,12714965 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02211298 0,12683257 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02211298 0,12651707 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02211298 0,12620313 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02211298 0,12589075 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02211298 0,12557991 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02211298 0,1252706 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02211298 0,12496281 ! neural tube patterning GO:0021532 6 5 0,000 0,02211298 0,12465652 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02211298 0,12435174 ! histone demethylation GO:0016577 9 5 0,000 0,02211298 0,12404844 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02211298 0,12374662 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02211298 0,12344627 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02211298 0,12314737 ! enteric nervous system development GO:0048484 8 5 0,000 0,02211298 0,12284991 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02211298 0,12255388 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02211298 0,12225928 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02211298 0,1219661 ! transcription termination GO:0006353 8 5 0,000 0,02211298 0,12167431 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02211298 0,12138392 ! plasminogen activation GO:0031639 5 5 0,000 0,02211298 0,12109491 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02211298 0,12080727 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02211298 0,120521 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02211298 0,12023608 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02211298 0,1199525 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02211298 0,11967026 ! apical protein localization GO:0045176 6 5 0,000 0,02211298 0,11938935 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02211298 0,11910975 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02211298 0,11883145 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02211298 0,11855446 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02211298 0,11827875 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02211298 0,11800432 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02211298 0,11773116 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02211298 0,11745927 ! glial cell migration GO:0008347 10 5 0,000 0,02211298 0,11718862 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02211298 0,11691922 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02211298 0,11665106 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02211298 0,11638412 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02211298 0,11611841 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02211298 0,1158539 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02211298 0,1155906 ! neural plate development GO:0001840 6 5 0,000 0,02211298 0,11532848 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,02211298 0,11506756 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02211298 0,11480781 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02211298 0,11454924 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02211298 0,11429182 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02211298 0,11403556 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02211298 0,11378045 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02211298 0,11352648 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02211298 0,11327363 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02211298 0,11302192 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02211298 0,11277131 ! spindle assembly GO:0051225 5 5 0,000 0,02211298 0,11252182 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02211298 0,11227343 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02211298 0,11202613 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02211298 0,11177992 ! organ regeneration GO:0031100 7 5 0,000 0,02211298 0,11153478 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02211298 0,11129073 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02211298 0,11104773 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02211298 0,1108058 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02211298 0,11056492 GO:0055081|anion homeostasis, ! aging GO:0007568 79 52 1,000 0,02256532 0,11258185 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,02256532 0,11233816 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,02338337 0,1161593 ! DNA catabolic process GO:0006308 67 54 1,000 0,02421352 0,12002394 ! detection of external stimulus GO:0009581 66 54 1,000 0,02421352 0,11976582 ! exocytosis GO:0006887 74 55 1,000 0,02505565 0,12366523 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,02590963 0,12760632 ! positive regulation of cell motion GO:0051272 99 56 1,000 0,02590963 0,12733366 ! tRNA transcription GO:0009304 11 6 0,000 0,0264773 0,12984604 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,0264773 0,12956977 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,0264773 0,12929468 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,0264773 0,12902075 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0264773 0,12874798 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,0264773 0,12847636 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,0264773 0,12820588 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,0264773 0,12793654 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,0264773 0,12766833 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,0264773 0,12740124 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,0264773 0,12713527 ! prostate gland development GO:0030850 9 6 0,000 0,0264773 0,1268704 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,0264773 0,12660664 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,0264773 0,12634397 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,0264773 0,12608239 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,0264773 0,12582189 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,0264773 0,12556246 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,0264773 0,1253041 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,0264773 0,1250468 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,0264773 0,12479056 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,0264773 0,12453536 ! neuron adhesion GO:0007158 9 6 0,000 0,0264773 0,12428121 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,0264773 0,12402809 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,0264773 0,123776 ! signal peptide processing GO:0006465 8 6 0,000 0,0264773 0,12352494 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,0264773 0,12327489 ! mRNA stabilization GO:0048255 15 6 0,000 0,0264773 0,12302585 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,0264773 0,12277781 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,0264773 0,12253077 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,0264773 0,12228473 ! opsonization GO:0008228 8 6 0,000 0,0264773 0,12203967 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,0264773 0,12179559 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,0264773 0,12155248 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,0264773 0,12131035 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,0264773 0,12106917 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,0264773 0,12082896 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0264773 0,12058969 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,0264773 0,12035137 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,0264773 0,12011399 ! mechanosensory behavior GO:0007638 8 6 0,000 0,0264773 0,11987755 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,0264773 0,11964203 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,0264773 0,11940744 ! response to interferon-gamma GO:0034341 12 6 0,000 0,0264773 0,11917376 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,0264773 0,118941 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,0264773 0,11870915 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0264773 0,1184782 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,0264773 0,11824814 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,0264773 0,11801898 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,0264773 0,1177907 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,0264773 0,11756331 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,0264773 0,11733679 ! thymic T cell selection GO:0045061 12 6 0,000 0,0264773 0,11711114 ! protein lipoylation GO:0009249 10 6 0,000 0,0264773 0,11688636 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,0264773 0,11666244 ! pigment granule organization GO:0048753 11 6 0,000 0,0264773 0,11643938 ! drug transport GO:0015893 6 6 0,000 0,0264773 0,11621716 ! cysteine metabolic process GO:0006534 7 6 0,000 0,0264773 0,1159958 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,0264773 0,11577527 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0264773 0,11555559 ! histidine metabolic process GO:0006547 6 6 0,000 0,0264773 0,11533673 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,0264773 0,1151187 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,0264773 0,1149015 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,0264773 0,11468511 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,0264773 0,11446954 ! adenohypophysis development GO:0021984 10 6 0,000 0,0264773 0,11425477 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,0264773 0,11404081 ! hyperosmotic response GO:0006972 8 6 0,000 0,0264773 0,11382765 ! microtubule nucleation GO:0007020 10 6 0,000 0,0264773 0,11361529 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,0264773 0,11340371 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,0264773 0,11319292 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,0264773 0,11298292 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,0264773 0,11277369 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,0264773 0,11256524 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,0264773 0,11235755 ! response to dietary excess GO:0002021 7 6 0,000 0,0264773 0,11215063 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,0264773 0,11194447 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,0264773 0,11173907 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,0264773 0,11153442 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,0264773 0,11133052 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,0264773 0,11112736 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,0264773 0,11092494 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0264773 0,11072326 ! neuron apoptosis GO:0051402 8 6 0,000 0,0264773 0,11052231 ! organic alcohol transport GO:0015850 9 6 0,000 0,0264773 0,11032209 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,0264773 0,11012259 ! T cell mediated immunity GO:0002456 12 6 0,000 0,0264773 0,10992381 ! carnitine transport GO:0015879 8 6 0,000 0,0264773 0,10972575 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,0264773 0,10952841 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,0264773 0,10933177 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0264773 0,10913583 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,0264773 0,1089406 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,0264773 0,10874606 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,0264773 0,10855222 ! parturition GO:0007567 12 6 0,000 0,0264773 0,10835906 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,0264773 0,1081666 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,0264773 0,10797481 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,0264773 0,10778371 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,0264773 0,10759327 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,0264773 0,10740352 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,0264773 0,10721443 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,0264773 0,107026 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,0264773 0,10683823 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,0264773 0,10665113 ! astrocyte development GO:0014002 14 6 0,000 0,0264773 0,10646467 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,0264773 0,10627887 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,0264773 0,10609372 ! interaction with symbiont GO:0051702 8 6 0,000 0,0264773 0,10590921 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,0264773 0,10572534 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0264773 0,1055421 ! eating behavior GO:0042755 6 6 0,000 0,0264773 0,1053595 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,0264773 0,10517754 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,0264773 0,1049962 ! response to copper ion GO:0046688 9 6 0,000 0,0264773 0,10481548 ! DNA topological change GO:0006265 8 6 0,000 0,0264773 0,10463538 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,0264773 0,10445591 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,0264773 0,10427704 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,0264773 0,10409879 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0264773 0,10392115 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0264773 0,10374411 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,0264773 0,10356768 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,0264773 0,10339184 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,0264773 0,1032166 ! gas homeostasis GO:0033483 11 6 0,000 0,0264773 0,10304195 ! hair follicle maturation GO:0048820 7 6 0,000 0,0264773 0,10286789 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,0264773 0,10269442 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,0264773 0,10252154 ! Schwann cell development GO:0014044 14 6 0,000 0,0264773 0,10234923 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,0264773 0,10217751 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,0264773 0,10200635 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0264773 0,10183577 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,0264773 0,10166577 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,0264773 0,10149632 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,0264773 0,10132744 ! histone ubiquitination GO:0016574 7 6 0,000 0,0264773 0,10115913 ! regulation of meiosis GO:0040020 10 6 0,000 0,0264773 0,10099137 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,0264773 0,10082416 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,0264773 0,10065751 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,0264773 0,10049141 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,0264773 0,10032585 ! membrane to membrane docking GO:0022614 12 6 0,000 0,0264773 0,10016084 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,0264773 0,09999638 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,0264773 0,09983245 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,0264773 0,09966906 ! receptor internalization GO:0031623 9 6 0,000 0,0264773 0,0995062 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,0264773 0,09934387 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,0264773 0,09918207 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0264773 0,0990208 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,0264773 0,09886005 ! protein deubiquitination GO:0016579 8 6 0,000 0,0264773 0,09869983 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,0264773 0,09854012 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,0264773 0,09838093 ! axonal fasciculation GO:0007413 9 6 0,000 0,0264773 0,09822225 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,0264773 0,09806408 ! thiamin metabolic process GO:0006772 6 6 0,000 0,0264773 0,09790642 ! midbrain development GO:0030901 6 6 0,000 0,0264773 0,09774927 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,0264773 0,09759262 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0264773 0,09743647 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,0264773 0,09728082 ! progesterone metabolic process GO:0042448 8 6 0,000 0,0264773 0,09712567 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,0264773 0,09697101 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,0264773 0,09681684 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,0264773 0,09666316 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,0264773 0,09650997 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,0264773 0,09635727 ! adult feeding behavior GO:0008343 6 6 0,000 0,0264773 0,09620504 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,0264773 0,0960533 ! blastocyst growth GO:0001832 15 6 0,000 0,0264773 0,09590204 ! pigment granule transport GO:0051904 12 6 0,000 0,0264773 0,09575125 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,0264773 0,09560093 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,0264773 0,09545109 ! catecholamine transport GO:0051937 7 6 0,000 0,0264773 0,09530171 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0264773 0,0951528 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,0264773 0,09500436 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,0264773 0,09485638 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,0264773 0,09470885 ! protein prenylation GO:0018342 10 6 0,000 0,0264773 0,09456179 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0264773 0,09441518 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,0264773 0,09426903 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,0264773 0,09412333 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,0264773 0,09397808 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,0264773 0,09383327 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,02677535 0,09474353 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,02677535 0,094598 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,02765268 0,09754779 ! viral reproductive process GO:0022415 87 58 1,000 0,02765268 0,0973984 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 1,000 0,02854151 0,10037533 ! activation of MAPK activity GO:0000187 84 59 1,000 0,02854151 0,10022208 ! lung development GO:0030324 94 59 1,000 0,02854151 0,10006931 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,02944172 0,10306841 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,02944172 0,10291177 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,03035319 0,10593678 ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,03035319 0,10577627 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,03082239 0,10724886 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,03082239 0,10708685 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03082239 0,10692534 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03082239 0,1067643 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,03082239 0,10660376 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03082239 0,10644369 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03082239 0,1062841 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,03082239 0,106125 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03082239 0,10596636 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,03082239 0,10580821 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03082239 0,10565052 ! reproductive behavior GO:0019098 12 7 0,000 0,03082239 0,1054933 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03082239 0,10533655 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,03082239 0,10518026 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,03082239 0,10502444 ! oligopeptide transport GO:0006857 11 7 0,000 0,03082239 0,10486908 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03082239 0,10471418 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03082239 0,10455973 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,03082239 0,10440574 ! RNA methylation GO:0001510 11 7 0,000 0,03082239 0,1042522 ! pericardium development GO:0060039 8 7 0,000 0,03082239 0,10409912 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03082239 0,10394648 ! fibril organization GO:0043206 13 7 0,000 0,03082239 0,10379429 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03082239 0,10364254 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03082239 0,10349124 ! lipoprotein transport GO:0042953 9 7 0,000 0,03082239 0,10334038 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03082239 0,10318995 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03082239 0,10303997 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03082239 0,10289042 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03082239 0,1027413 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03082239 0,10259262 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03082239 0,10244436 ! chemosensory behavior GO:0007635 9 7 0,000 0,03082239 0,10229653 ! microtubule bundle formation GO:0001578 8 7 0,000 0,03082239 0,10214913 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,03082239 0,10200215 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03082239 0,1018556 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03082239 0,10170947 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03082239 0,10156375 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03082239 0,10141845 ! reflex GO:0060004 12 7 0,000 0,03082239 0,10127357 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03082239 0,1011291 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03082239 0,10098504 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03082239 0,10084139 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03082239 0,10069815 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,03082239 0,10055532 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03082239 0,10041289 ! spinal cord patterning GO:0021511 7 7 0,000 0,03082239 0,10027086 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,03082239 0,10012923 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,03082239 0,09998801 ! adrenal gland development GO:0030325 17 7 0,000 0,03082239 0,09984718 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03082239 0,09970675 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03082239 0,09956671 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03082239 0,09942707 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03082239 0,09928781 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03082239 0,09914895 ! endosome organization GO:0007032 10 7 0,000 0,03082239 0,09901047 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03082239 0,09887238 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03082239 0,09873468 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03082239 0,09859735 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03082239 0,09846041 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03082239 0,09832385 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,03082239 0,09818767 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03082239 0,09805186 ! galactose metabolic process GO:0006012 10 7 0,000 0,03082239 0,09791643 ! vesicle fusion GO:0006906 15 7 0,000 0,03082239 0,09778138 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03082239 0,09764669 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,03082239 0,09751238 ! organ growth GO:0035265 11 7 0,000 0,03082239 0,09737843 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03082239 0,09724485 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,03082239 0,09711164 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03082239 0,09697879 ! retinol metabolic process GO:0042572 9 7 0,000 0,03082239 0,09684631 ! behavioral fear response GO:0001662 13 7 0,000 0,03082239 0,09671418 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,03082239 0,09658242 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03082239 0,09645102 ! rRNA modification GO:0000154 12 7 0,000 0,03082239 0,09631997 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03082239 0,09618928 ! response to UV-B GO:0010224 11 7 0,000 0,03082239 0,09605894 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03082239 0,09592895 ! intermediate filament organization GO:0045109 11 7 0,000 0,03082239 0,09579932 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,03082239 0,09567004 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03082239 0,0955411 ! fibrinolysis GO:0042730 9 7 0,000 0,03082239 0,09541251 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,03082239 0,09528427 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03082239 0,09515637 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03082239 0,09502882 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03082239 0,0949016 ! response to tropane GO:0014073 13 7 0,000 0,03082239 0,09477473 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,03082239 0,09464819 ! melanosome localization GO:0032400 10 7 0,000 0,03082239 0,094522 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03082239 0,09439614 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03082239 0,09427061 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03082239 0,09414541 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03082239 0,09402055 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03082239 0,09389602 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03082239 0,09377182 ! mast cell activation GO:0045576 9 7 0,000 0,03082239 0,09364795 ! multicellular organismal aging GO:0010259 11 7 0,000 0,03082239 0,0935244 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,03082239 0,09340118 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03082239 0,09327829 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03082239 0,09315571 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,03082239 0,09303346 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,03082239 0,09291153 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03082239 0,09278992 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,03082239 0,09266862 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03082239 0,09254765 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03082239 0,09242698 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03082239 0,09230664 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03082239 0,0921866 ! neuroblast proliferation GO:0007405 13 7 0,000 0,03082239 0,09206688 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03082239 0,09194747 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,03082239 0,09182836 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,03082239 0,09170957 ! diuresis GO:0030146 12 7 0,000 0,03082239 0,09159108 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03082239 0,0914729 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03082239 0,09135502 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03082239 0,09123745 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03082239 0,09112018 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03082239 0,09100321 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03082239 0,09088654 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03082239 0,09077016 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03082239 0,09065409 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03082239 0,09053831 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03082239 0,09042283 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03082239 0,09030764 ! lymph node development GO:0048535 9 7 0,000 0,03082239 0,09019274 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,03082239 0,09007814 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03082239 0,08996383 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,03082239 0,08984981 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03082239 0,08973607 ! ATP catabolic process GO:0006200 10 7 0,000 0,03082239 0,08962263 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03082239 0,08950947 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03082239 0,08939659 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03082239 0,089284 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03082239 0,08917169 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03082239 0,08905967 ! muscle adaptation GO:0043500 12 7 0,000 0,03082239 0,08894793 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03082239 0,08883646 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03082239 0,08872528 ! retina homeostasis GO:0001895 9 7 0,000 0,03082239 0,08861437 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03082239 0,08850374 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,03082239 0,08839339 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,03082239 0,08828331 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,03082239 0,0881735 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03082239 0,08806397 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03082239 0,08795471 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03082239 0,08784572 ! respiratory tube development GO:0030323 99 62 1,000 0,03127581 0,08902768 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,03220947 0,09157204 GO:0090046|regulation of transcription regulator activity, ! viral reproduction GO:0016032 92 63 1,000 0,03220947 0,09145899 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,03315405 0,09402504 ! respiratory system development GO:0060541 100 64 1,000 0,03315405 0,09390924 ! B cell activation GO:0042113 104 65 1,000 0,03410943 0,09649654 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,0350755 0,09910769 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03514833 0,09919162 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03514833 0,09907006 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,03514833 0,0989488 ! axon extension GO:0048675 11 8 0,000 0,03514833 0,09882783 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,03514833 0,09870716 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03514833 0,09858679 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03514833 0,09846671 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03514833 0,09834692 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03514833 0,09822742 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03514833 0,09810821 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,03514833 0,09798929 ! phosphate transport GO:0006817 10 8 0,000 0,03514833 0,09787066 ! N-glycan processing GO:0006491 12 8 0,000 0,03514833 0,09775232 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03514833 0,09763426 ! UTP metabolic process GO:0046051 8 8 0,000 0,03514833 0,09751649 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03514833 0,097399 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03514833 0,09728179 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,03514833 0,09716486 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03514833 0,09704822 ! succinate metabolic process GO:0006105 14 8 0,000 0,03514833 0,09693185 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03514833 0,09681577 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03514833 0,09669996 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,03514833 0,09658443 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03514833 0,09646917 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03514833 0,09635419 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03514833 0,09623948 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03514833 0,09612505 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03514833 0,09601089 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,03514833 0,09589699 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03514833 0,09578337 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03514833 0,09567002 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03514833 0,09555693 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03514833 0,09544412 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,03514833 0,09533156 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03514833 0,09521928 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03514833 0,09510725 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03514833 0,0949955 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03514833 0,094884 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,03514833 0,09477276 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03514833 0,09466179 ! melanin metabolic process GO:0006582 12 8 0,000 0,03514833 0,09455107 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03514833 0,09444061 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03514833 0,09433042 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,03514833 0,09422047 ! macrophage activation GO:0042116 12 8 0,000 0,03514833 0,09411079 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03514833 0,09400136 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03514833 0,09389218 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03514833 0,09378326 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03514833 0,09367458 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03514833 0,09356616 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,03514833 0,093458 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03514833 0,09335008 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03514833 0,09324241 ! ruffle organization GO:0031529 11 8 0,000 0,03514833 0,09313498 ! osteoblast development GO:0002076 13 8 0,000 0,03514833 0,09302781 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,03514833 0,09292088 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03514833 0,0928142 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03514833 0,09270776 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03514833 0,09260157 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,03514833 0,09249561 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03514833 0,0923899 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03514833 0,09228444 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03514833 0,09217921 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03514833 0,09207422 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,03514833 0,09196947 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,03514833 0,09186496 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03514833 0,09176069 ! segment specification GO:0007379 10 8 0,000 0,03514833 0,09165665 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,03514833 0,09155285 ! cellular extravasation GO:0045123 11 8 0,000 0,03514833 0,09144928 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03514833 0,09134595 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,03514833 0,09124285 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03514833 0,09113998 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,03514833 0,09103735 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03514833 0,09093495 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03514833 0,09083277 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03514833 0,09073083 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03514833 0,09062911 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03514833 0,09052762 ! nucleosome disassembly GO:0006337 12 8 0,000 0,03514833 0,09042636 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03514833 0,09032533 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03514833 0,09022452 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03514833 0,09012393 ! icosanoid secretion GO:0032309 12 8 0,000 0,03514833 0,09002357 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,03514833 0,08992343 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03514833 0,08982352 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03514833 0,08972383 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03514833 0,08962435 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03514833 0,0895251 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03514833 0,08942607 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03514833 0,08932726 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,03514833 0,08922866 ! sterol catabolic process GO:0016127 9 8 0,000 0,03514833 0,08913028 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03514833 0,08903212 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03514833 0,08893418 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03514833 0,08883645 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03514833 0,08873893 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03514833 0,08864163 ! prophase GO:0051324 11 8 0,000 0,03514833 0,08854454 ! S phase GO:0051320 8 8 0,000 0,03514833 0,08844767 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03514833 0,088351 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,03514833 0,08825455 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03514833 0,08815831 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03514833 0,08806227 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03514833 0,08796645 ! hormone catabolic process GO:0042447 13 8 0,000 0,03514833 0,08787083 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03514833 0,08777542 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03514833 0,08768022 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03514833 0,08758523 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03514833 0,08749044 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03514833 0,08739586 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03514833 0,08730148 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03514833 0,0872073 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03514833 0,08711333 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03514833 0,08701955 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03514833 0,08692599 ! lamellipodium assembly GO:0030032 9 8 0,000 0,03514833 0,08683262 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03514833 0,08673945 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,03514833 0,08664648 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,03514833 0,08655371 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,03703929 0,0911127 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,03803678 0,09346645 ! response to drug GO:0042493 108 69 1,000 0,03803678 0,0933667 ! regulation of catabolic process GO:0009894 106 70 1,000 0,03904452 0,09573817 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03945521 0,09664216 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03945521 0,09653935 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,03945521 0,09643676 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03945521 0,09633439 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03945521 0,09623223 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03945521 0,09613029 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03945521 0,09602856 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03945521 0,09592705 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03945521 0,09582576 ! GTP metabolic process GO:0046039 9 9 0,000 0,03945521 0,09572467 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03945521 0,09562381 ! social behavior GO:0035176 14 9 0,000 0,03945521 0,09552315 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03945521 0,0954227 ! artery development GO:0060840 19 9 0,000 0,03945521 0,09532247 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03945521 0,09522245 ! response to pain GO:0048265 16 9 0,000 0,03945521 0,09512263 ! protein complex disassembly GO:0043241 17 9 0,000 0,03945521 0,09502303 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03945521 0,09492363 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03945521 0,09482444 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03945521 0,09472546 ! lung alveolus development GO:0048286 17 9 0,000 0,03945521 0,09462669 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03945521 0,09452812 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,03945521 0,09442975 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03945521 0,09433159 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03945521 0,09423364 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03945521 0,09413588 ! protein targeting to ER GO:0045047 19 9 0,000 0,03945521 0,09403833 ! T cell selection GO:0045058 18 9 0,000 0,03945521 0,09394098 ! endoderm development GO:0007492 12 9 0,000 0,03945521 0,09384384 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03945521 0,09374689 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03945521 0,09365015 ! arginine catabolic process GO:0006527 10 9 0,000 0,03945521 0,0935536 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03945521 0,09345725 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03945521 0,0933611 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03945521 0,09326515 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03945521 0,0931694 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,03945521 0,09307384 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03945521 0,09297847 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03945521 0,09288331 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03945521 0,09278833 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03945521 0,09269356 ! mannose metabolic process GO:0006013 9 9 0,000 0,03945521 0,09259897 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03945521 0,09250458 ! receptor clustering GO:0043113 15 9 0,000 0,03945521 0,09241038 ! epithelial cell development GO:0002064 10 9 0,000 0,03945521 0,09231637 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03945521 0,09222255 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03945521 0,09212893 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03945521 0,09203549 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03945521 0,09194224 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03945521 0,09184918 ! motor axon guidance GO:0008045 14 9 0,000 0,03945521 0,09175631 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03945521 0,09166363 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03945521 0,09157113 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03945521 0,09147882 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03945521 0,0913867 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03945521 0,09129476 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03945521 0,09120301 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03945521 0,09111144 ! response to amine stimulus GO:0014075 13 9 0,000 0,03945521 0,09102005 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03945521 0,09092885 ! erythrocyte development GO:0048821 11 9 0,000 0,03945521 0,09083783 ! renal water homeostasis GO:0003091 14 9 0,000 0,03945521 0,09074699 ! postreplication repair GO:0006301 11 9 0,000 0,03945521 0,09065634 ! mRNA cleavage GO:0006379 13 9 0,000 0,03945521 0,09056586 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03945521 0,09047556 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03945521 0,09038545 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03945521 0,09029551 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03945521 0,09020576 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03945521 0,09011618 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03945521 0,09002678 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03945521 0,08993755 ! acid secretion GO:0046717 14 9 0,000 0,03945521 0,08984851 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03945521 0,08975964 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03945521 0,08967094 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03945521 0,08958242 ! purine base metabolic process GO:0006144 18 9 0,000 0,03945521 0,08949407 ! oocyte differentiation GO:0009994 12 9 0,000 0,03945521 0,0894059 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03945521 0,08931791 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03945521 0,08923008 ! spleen development GO:0048536 15 9 0,000 0,03945521 0,08914243 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03945521 0,08905495 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03945521 0,08896764 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03945521 0,0888805 ! detection of calcium ion GO:0005513 13 9 0,000 0,03945521 0,08879353 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03945521 0,08870674 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03945521 0,08862011 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03945521 0,08853365 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03945521 0,08844736 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03945521 0,08836124 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03945521 0,08827528 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03945521 0,0881895 ! prepulse inhibition GO:0060134 14 9 0,000 0,03945521 0,08810388 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,03945521 0,08801842 ! insulin secretion GO:0030073 17 9 0,000 0,03945521 0,08793313 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03945521 0,08784801 ! response to nicotine GO:0035094 16 9 0,000 0,03945521 0,08776305 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03945521 0,08767825 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03945521 0,08759362 ! localization within membrane GO:0051668 15 9 0,000 0,03945521 0,08750915 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,04006241 0,08877027 ! response to hypoxia GO:0001666 132 72 1,000 0,04109033 0,0909603 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,04109033 0,09087284 ! negative regulation of transport GO:0051051 116 73 1,000 0,04212817 0,09307858 ! response to oxygen levels GO:0070482 137 74 1,000 0,04317584 0,09530176 ! protein import into nucleus GO:0006606 118 74 1,000 0,04317584 0,09521038 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,04374311 0,09636893 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,04374311 0,09627671 ! neuron fate specification GO:0048665 11 10 0,000 0,04374311 0,09618467 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,04374311 0,0960928 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,04374311 0,09600111 ! thyroid gland development GO:0030878 19 10 0,000 0,04374311 0,09590959 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,04374311 0,09581825 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,04374311 0,09572708 ! synapsis GO:0007129 13 10 0,000 0,04374311 0,09563609 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,04374311 0,09554526 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,04374311 0,09545461 ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,04374311 0,09536414 ! sulfate transport GO:0008272 12 10 0,000 0,04374311 0,09527383 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,04374311 0,09518369 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,04374311 0,09509373 ! phospholipid efflux GO:0033700 16 10 0,000 0,04374311 0,09500393 ! hippocampus development GO:0021766 19 10 0,000 0,04374311 0,09491431 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,04374311 0,09482485 ! blood vessel remodeling GO:0001974 21 10 0,000 0,04374311 0,09473556 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,04374311 0,09464644 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,04374311 0,09455748 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,04374311 0,0944687 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,04374311 0,09438008 ! pathogenesis GO:0009405 13 10 0,000 0,04374311 0,09429162 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,04374311 0,09420334 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04374311 0,09411521 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,04374311 0,09402726 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,04374311 0,09393946 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,04374311 0,09385183 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,04374311 0,09376437 ! melanocyte differentiation GO:0030318 15 10 0,000 0,04374311 0,09367706 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,04374311 0,09358992 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,04374311 0,09350294 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04374311 0,09341612 ! B cell proliferation GO:0042100 14 10 0,000 0,04374311 0,09332947 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,04374311 0,09324297 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,04374311 0,09315663 ! forebrain cell migration GO:0021885 17 10 0,000 0,04374311 0,09307046 ! lipid digestion GO:0044241 15 10 0,000 0,04374311 0,09298444 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,04374311 0,09289858 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,04374311 0,09281288 ! UV protection GO:0009650 14 10 0,000 0,04374311 0,09272734 ! entry into host cell GO:0030260 20 10 0,000 0,04374311 0,09264196 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,04374311 0,09255673 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,04374311 0,09247166 ! negative regulation of ossification GO:0030279 19 10 0,000 0,04374311 0,09238674 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,04374311 0,09230199 ! regulation of bone resorption GO:0045124 24 10 0,000 0,04374311 0,09221738 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,04374311 0,09213293 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,04374311 0,09204864 ! regulation of organ growth GO:0046620 11 10 0,000 0,04374311 0,0919645 ! response to dsRNA GO:0043331 18 10 0,000 0,04374311 0,09188051 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,04374311 0,09179668 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04374311 0,091713 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,04374311 0,09162948 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,04374311 0,0915461 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,04374311 0,09146288 ! cranial nerve development GO:0021545 12 10 0,000 0,04374311 0,0913798 ! fucose catabolic process GO:0019317 16 10 0,000 0,04374311 0,09129688 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,04374311 0,09121411 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,04374311 0,09113149 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,04374311 0,09104902 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04374311 0,09096669 ! zymogen activation GO:0031638 14 10 0,000 0,04374311 0,09088452 ! salivary gland development GO:0007431 22 10 0,000 0,04374311 0,09080249 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04374311 0,09072062 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,04374311 0,09063889 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,04374311 0,0905573 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,04374311 0,09047587 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,04374311 0,09039458 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,04374311 0,09031343 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04374311 0,09023243 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,04374311 0,09015158 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,04374311 0,09007087 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,04374311 0,08999031 ! detection of bacterium GO:0016045 10 10 0,000 0,04374311 0,08990989 ! embryonic gut development GO:0048566 11 10 0,000 0,04374311 0,08982961 ! activation of innate immune response GO:0002218 10 10 0,000 0,04374311 0,08974948 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,04374311 0,08966949 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,04374311 0,08958964 ! developmental induction GO:0031128 13 10 0,000 0,04374311 0,08950993 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,04374311 0,08943037 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,04374311 0,08935094 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,04374311 0,08927166 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,04374311 0,08919252 ! nuclear import GO:0051170 121 75 1,000 0,04423322 0,09011197 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,04530021 0,09220397 ! protein ubiquitination GO:0016567 125 77 1,000 0,04637671 0,09431161 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,04637671 0,0942283 ! rRNA transcription GO:0009303 17 11 0,000 0,04801212 0,09746502 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,04801212 0,09737908 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,04801212 0,09729328 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,04801212 0,09720763 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,04801212 0,09712214 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,04801212 0,0970368 GO:0000725|recombinational repair, ! Golgi vesicle budding GO:0048194 17 11 0,000 0,04801212 0,0969516 ! RNA polyadenylation GO:0043631 19 11 0,000 0,04801212 0,09686656 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,04801212 0,09678166 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,04801212 0,09669691 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,04801212 0,09661231 ! T cell proliferation GO:0042098 20 11 0,000 0,04801212 0,09652786 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,04801212 0,09644356 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,04801212 0,0963594 ! bone resorption GO:0045453 16 11 0,000 0,04801212 0,09627539 ! regulated secretory pathway GO:0045055 14 11 0,000 0,04801212 0,09619153 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,04801212 0,09610781 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,04801212 0,09602424 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,04801212 0,09594081 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,04801212 0,09585753 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,04801212 0,09577439 ! plasma membrane organization GO:0007009 18 11 0,000 0,04801212 0,0956914 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,04801212 0,09560855 ! focal adhesion formation GO:0048041 24 11 0,000 0,04801212 0,09552584 ! mitotic spindle organization GO:0007052 15 11 0,000 0,04801212 0,09544328 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,04801212 0,09536086 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,04801212 0,09527858 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,04801212 0,09519644 ! adult heart development GO:0007512 11 11 0,000 0,04801212 0,09511445 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,04801212 0,09503259 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,04801212 0,09495088 ! temperature homeostasis GO:0001659 16 11 0,000 0,04801212 0,09486931 ! L-glutamate transport GO:0015813 16 11 0,000 0,04801212 0,09478787 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,04801212 0,09470658 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,04801212 0,09462543 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,04801212 0,09454441 ! stem cell development GO:0048864 29 11 0,000 0,04801212 0,09446354 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,04801212 0,0943828 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,04801212 0,0943022 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,04801212 0,09422173 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,04801212 0,09414141 ! vasoconstriction GO:0042310 15 11 0,000 0,04801212 0,09406122 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,04801212 0,09398117 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,04801212 0,09390125 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,04801212 0,09382147 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,04801212 0,09374183 ! ribosome assembly GO:0042255 13 11 0,000 0,04801212 0,09366232 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,04801212 0,09358294 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,04801212 0,0935037 ! chromatin silencing GO:0006342 19 11 0,000 0,04801212 0,0934246 ! nucleosome positioning GO:0016584 13 11 0,000 0,04801212 0,09334562 ! T cell homeostasis GO:0043029 20 11 0,000 0,04801212 0,09326678 ! regulation of isotype switching GO:0045191 19 11 0,000 0,04801212 0,09318808 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,04801212 0,0931095 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,04801212 0,09303106 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,04801212 0,09295275 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,04801212 0,09287458 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,04801212 0,09279653 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,04801212 0,09271862 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,04801212 0,09264083 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,04801212 0,09256318 ! male genitalia development GO:0030539 13 11 0,000 0,04801212 0,09248566 ! cholesterol efflux GO:0033344 19 11 0,000 0,04801212 0,09240826 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,04801212 0,092331 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,04801212 0,09225386 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,04801212 0,09217686 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,04801212 0,09209998 GO:0010829|negative regulation of glucose transport, ! regulation of organic acid transport GO:0032890 17 11 0,000 0,04801212 0,09202323 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,04801212 0,09194661 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,04801212 0,09187011 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,04801212 0,09179374 ! lysogeny GO:0030069 18 11 0,000 0,04801212 0,0917175 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,04801212 0,09164139 ! acrosome reaction GO:0007340 13 11 0,000 0,04801212 0,0915654 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,04801212 0,09148954 ! T cell activation GO:0042110 134 79 1,000 0,04855781 0,09245278 ! protein localization in nucleus GO:0034504 133 80 1,000 0,04966221 0,09447731 ! mRNA transport GO:0051028 121 81 1,000 0,0507757 0,09651579 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,0507757 0,09643609 ! detection of stimulus GO:0051606 108 82 1,000 0,05189818 0,09848665 ! lactation GO:0007595 20 12 0,000 0,05226231 0,09909588 ! reproductive cellular process GO:0048610 14 12 0,000 0,05226231 0,09901426 ! tRNA modification GO:0006400 14 12 0,000 0,05226231 0,09893276 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,05226231 0,0988514 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,05226231 0,09877018 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,05226231 0,09868909 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,05226231 0,09860813 ! non-recombinational repair GO:0000726 19 12 0,000 0,05226231 0,0985273 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,05226231 0,09844661 ! peroxisomal transport GO:0043574 21 12 0,000 0,05226231 0,09836605 ! cartilage condensation GO:0001502 18 12 0,000 0,05226231 0,09828562 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,05226231 0,09820532 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,05226231 0,09812515 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,05226231 0,09804511 ! heart looping GO:0001947 15 12 0,000 0,05226231 0,09796521 ! palate development GO:0060021 15 12 0,000 0,05226231 0,09788543 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,05226231 0,09780578 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,05226231 0,09772627 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,05226231 0,09764688 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,05226231 0,09756762 ! arginine metabolic process GO:0006525 13 12 0,000 0,05226231 0,09748849 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,05226231 0,09740949 ! methionine metabolic process GO:0006555 13 12 0,000 0,05226231 0,09733061 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,05226231 0,09725187 ! Golgi organization GO:0007030 18 12 0,000 0,05226231 0,09717325 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,05226231 0,09709476 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,05226231 0,09701639 ! monoamine transport GO:0015844 13 12 0,000 0,05226231 0,09693815 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05226231 0,09686004 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,05226231 0,09678205 ! L-amino acid transport GO:0015807 20 12 0,000 0,05226231 0,09670419 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,05226231 0,09662645 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,05226231 0,09654884 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,05226231 0,09647135 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05226231 0,09639399 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,05226231 0,09631675 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,05226231 0,09623964 ! cerebellum development GO:0021549 13 12 0,000 0,05226231 0,09616265 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,05226231 0,09608578 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,05226231 0,09600903 ! histone methylation GO:0016571 15 12 0,000 0,05226231 0,09593241 ! autonomic nervous system development GO:0048483 23 12 0,000 0,05226231 0,09585591 ! gland morphogenesis GO:0022612 23 12 0,000 0,05226231 0,09577953 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,05226231 0,09570327 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,05226231 0,09562713 ! regulation of epidermis development GO:0045682 17 12 0,000 0,05226231 0,09555112 ! intestinal absorption GO:0050892 19 12 0,000 0,05226231 0,09547522 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,05226231 0,09539945 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,05226231 0,0953238 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,05226231 0,09524826 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,05226231 0,09517285 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,05226231 0,09509755 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,05226231 0,09502238 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,05226231 0,09494732 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,05226231 0,09487238 ! response to cold GO:0009409 14 12 0,000 0,05226231 0,09479756 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,05531861 0,10026225 ! transcription initiation GO:0006352 118 85 1,000 0,05531861 0,10018331 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,05531861 0,10010448 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,05649376 0,10215067 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,05649376 0,10207043 ! cGMP metabolic process GO:0046068 16 13 0,000 0,05649376 0,10199031 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,05649376 0,10191032 ! water transport GO:0006833 17 13 0,000 0,05649376 0,10183045 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,05649376 0,10175071 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,05649376 0,10167109 ! lipid localization GO:0010876 24 13 0,000 0,05649376 0,1015916 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,05649376 0,10151223 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,05649376 0,10143299 ! organelle fusion GO:0048284 28 13 0,000 0,05649376 0,10135387 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,05649376 0,10127487 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,05649376 0,10119599 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,05649376 0,10111724 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,05649376 0,10103861 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,05649376 0,10096011 ! response to hexose stimulus GO:0009746 19 13 0,000 0,05649376 0,10088172 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,05649376 0,10080346 ! glutamate metabolic process GO:0006536 18 13 0,000 0,05649376 0,10072532 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,05649376 0,10064729 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,05649376 0,10056939 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,05649376 0,10049161 ! NAD metabolic process GO:0019674 21 13 0,000 0,05649376 0,10041395 ! exocrine system development GO:0035272 27 13 0,000 0,05649376 0,10033641 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,05649376 0,10025899 ! bone mineralization GO:0030282 15 13 0,000 0,05649376 0,10018169 ! regulation of exocytosis GO:0017157 17 13 0,000 0,05649376 0,10010451 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,05649376 0,10002745 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,05649376 0,09995051 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,05649376 0,09987368 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,05649376 0,09979697 ! genitalia development GO:0048806 15 13 0,000 0,05649376 0,09972038 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,05649376 0,09964391 ! cellular pigmentation GO:0033059 24 13 0,000 0,05649376 0,09956755 ! tissue regeneration GO:0042246 21 13 0,000 0,05649376 0,09949131 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,05649376 0,09941519 ! cofactor transport GO:0051181 19 13 0,000 0,05649376 0,09933919 ! NADP metabolic process GO:0006739 18 13 0,000 0,05649376 0,0992633 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,05649376 0,09918752 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,05649376 0,09911187 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05649376 0,09903632 ! gas transport GO:0015669 18 13 0,000 0,05649376 0,0989609 ! regulation of RNA stability GO:0043487 28 13 0,000 0,05649376 0,09888558 ! heme biosynthetic process GO:0006783 20 13 0,000 0,05649376 0,09881039 ! regulation of axon extension GO:0030516 23 13 0,000 0,05649376 0,0987353 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,05649376 0,09866033 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,05649376 0,09858548 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,05649376 0,09851073 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,05649376 0,0984361 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,05649376 0,09836159 ! cellular defense response GO:0006968 102 87 1,000 0,05764205 0,10028496 ! female pregnancy GO:0007565 130 87 1,000 0,05764205 0,10020916 ! establishment of RNA localization GO:0051236 128 88 1,000 0,05881642 0,10217355 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 1,000 0,05881642 0,10209644 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,05999911 0,10407085 ! reproductive developmental process GO:0003006 127 89 1,000 0,05999911 0,10399243 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,06070657 0,10513939 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,06070657 0,10506028 ! neuron maturation GO:0042551 21 14 0,000 0,06070657 0,10498128 ! regulation of S phase GO:0033261 18 14 0,000 0,06070657 0,10490241 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,06070657 0,10482365 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,06070657 0,10474502 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,06070657 0,1046665 ! inositol metabolic process GO:0006020 20 14 0,000 0,06070657 0,1045881 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,06070657 0,10450981 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,06070657 0,10443164 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,06070657 0,10435359 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,06070657 0,10427566 ! gene silencing by RNA GO:0031047 20 14 0,000 0,06070657 0,10419784 ! response to cAMP GO:0051591 19 14 0,000 0,06070657 0,10412014 ! limbic system development GO:0021761 25 14 0,000 0,06070657 0,10404255 ! startle response GO:0001964 21 14 0,000 0,06070657 0,10396508 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,06070657 0,10388773 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,06070657 0,10381049 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,06070657 0,10373336 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,06070657 0,10365635 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,06070657 0,10357946 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,06070657 0,10350267 ! glycine metabolic process GO:0006544 22 14 0,000 0,06070657 0,10342601 ! pituitary gland development GO:0021983 23 14 0,000 0,06070657 0,10334945 ! lysosomal transport GO:0007041 20 14 0,000 0,06070657 0,10327301 ! regulation of heart rate GO:0002027 23 14 0,000 0,06070657 0,10319668 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,06070657 0,10312046 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,06070657 0,10304436 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,06070657 0,10296837 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,06070657 0,10289249 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,06070657 0,10281672 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,06070657 0,10274107 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,06070657 0,10266552 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,06070657 0,10259009 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,06070657 0,10251476 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06070657 0,10243955 ! mRNA splice site selection GO:0006376 26 14 0,000 0,06070657 0,10236445 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,06070657 0,10228946 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,06070657 0,10221457 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,06070657 0,1021398 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,06070657 0,10206514 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,06070657 0,10199058 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,06070657 0,10191614 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,06070657 0,1018418 ! muscle maintenance GO:0046716 19 14 0,000 0,06070657 0,10176757 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,06070657 0,10169345 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,06070657 0,10161944 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,06070657 0,10154553 ! cell killing GO:0001906 20 14 0,000 0,06070657 0,10147174 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,06070657 0,10139805 ! cilium assembly GO:0042384 20 14 0,000 0,06070657 0,10132446 ! peptide hormone secretion GO:0030072 23 14 0,000 0,06070657 0,10125098 ! RNA localization GO:0006403 135 91 1,000 0,06238902 0,1039817 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,06359606 0,10591668 ! cell fate commitment GO:0045165 141 92 1,000 0,06359606 0,10584004 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,06481103 0,10778407 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,0649008 0,10785538 ! positive regulation of cell size GO:0045793 20 15 0,000 0,0649008 0,10777751 ! metencephalon development GO:0022037 19 15 0,000 0,0649008 0,10769975 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,0649008 0,1076221 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,0649008 0,10754456 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,0649008 0,10746713 ! skin development GO:0043588 25 15 0,000 0,0649008 0,10738982 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,0649008 0,10731261 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,0649008 0,10723552 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,0649008 0,10715854 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,0649008 0,10708167 ! bile acid metabolic process GO:0008206 22 15 0,000 0,0649008 0,10700491 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,0649008 0,10692826 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,0649008 0,10685172 ! adult walking behavior GO:0007628 25 15 0,000 0,0649008 0,10677528 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,0649008 0,10669896 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,0649008 0,10662275 ! myoblast differentiation GO:0045445 27 15 0,000 0,0649008 0,10654664 ! centrosome cycle GO:0007098 16 15 0,000 0,0649008 0,10647065 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,0649008 0,10639476 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,0649008 0,10631898 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,0649008 0,10624331 ! cerebral cortex development GO:0021987 29 15 0,000 0,0649008 0,10616774 ! response to osmotic stress GO:0006970 22 15 0,000 0,0649008 0,10609229 ! vesicle coating GO:0006901 25 15 0,000 0,0649008 0,10601694 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,0649008 0,10594169 ! DNA integration GO:0015074 22 15 0,000 0,0649008 0,10586656 ! peptide secretion GO:0002790 27 15 0,000 0,0649008 0,10579153 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,0649008 0,10571661 ! regulation of vasodilation GO:0042312 24 15 0,000 0,0649008 0,10564179 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,0649008 0,10556708 ! neuron recognition GO:0008038 22 15 0,000 0,0649008 0,10549247 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,0649008 0,10541797 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,0649008 0,10534358 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,0649008 0,10526929 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,0649008 0,1051951 ! biomineral formation GO:0031214 18 15 0,000 0,0649008 0,10512102 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,0649008 0,10504704 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,0649008 0,10497317 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,0649008 0,1048994 ! dopamine metabolic process GO:0042417 30 15 0,000 0,0649008 0,10482574 ! organic cation transport GO:0015695 19 15 0,000 0,0649008 0,10475217 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,0649008 0,10467871 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,0649008 0,10460536 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,0649008 0,10453211 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 27 15 0,000 0,0649008 0,10445896 ! peptide hormone processing GO:0016486 19 15 0,000 0,0649008 0,10438591 ! angiogenesis GO:0001525 149 95 1,000 0,06726439 0,10811189 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,0685026 0,11002513 ! protein maturation GO:0051604 129 96 1,000 0,0685026 0,10994835 ! response to light stimulus GO:0009416 153 96 1,000 0,0685026 0,10987168 ! protein secretion GO:0009306 27 16 0,000 0,06907655 0,11071502 ! hormone secretion GO:0046879 25 16 0,000 0,06907655 0,11063793 ! bone remodeling GO:0046849 24 16 0,000 0,06907655 0,11056093 ! endothelial cell migration GO:0043542 22 16 0,000 0,06907655 0,11048405 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,06907655 0,11040727 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06907655 0,1103306 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,06907655 0,11025403 ! glial cell development GO:0021782 24 16 0,000 0,06907655 0,11017757 ! patterning of blood vessels GO:0001569 24 16 0,000 0,06907655 0,11010122 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,06907655 0,11002497 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,06907655 0,10994883 ! protein polyubiquitination GO:0000209 26 16 0,000 0,06907655 0,10987279 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,06907655 0,10979686 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,06907655 0,10972104 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,06907655 0,10964531 ! fructose metabolic process GO:0006000 20 16 0,000 0,06907655 0,1095697 ! regulation of protein binding GO:0043393 27 16 0,000 0,06907655 0,10949418 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,06907655 0,10941877 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,06907655 0,10934347 ! protein export from nucleus GO:0006611 24 16 0,000 0,06907655 0,10926827 ! negative regulation of immune response GO:0050777 28 16 0,000 0,06907655 0,10919317 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,06907655 0,10911817 ! DNA replication initiation GO:0006270 25 16 0,000 0,06907655 0,10904328 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,06907655 0,10896849 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,06907655 0,1088938 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,06907655 0,10881922 ! diencephalon development GO:0021536 25 16 0,000 0,06907655 0,10874474 ! oogenesis GO:0048477 23 16 0,000 0,06907655 0,10867036 ! neural crest cell migration GO:0001755 24 16 0,000 0,06907655 0,10859608 ! G1 phase GO:0051318 27 16 0,000 0,06907655 0,1085219 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,06907655 0,10844782 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,06907655 0,10837385 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,06907655 0,10829997 ! steroid catabolic process GO:0006706 22 16 0,000 0,06907655 0,1082262 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,06907655 0,10815253 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,06907655 0,10807895 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,06907655 0,10800548 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,06907655 0,10793211 ! sperm-egg recognition GO:0035036 16 16 0,000 0,06907655 0,10785883 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,06907655 0,10778566 ! nerve development GO:0021675 18 16 0,000 0,06907655 0,10771258 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,06907655 0,10763961 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,06907655 0,10756673 ! negative regulation of translation GO:0017148 22 16 0,000 0,06907655 0,10749395 ! protein import GO:0017038 156 99 1,000 0,07226226 0,11237539 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,07226226 0,11229946 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,07323388 0,11373257 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,07323388 0,11365583 ! negative regulation of defense response GO:0031348 19 17 0,000 0,07323388 0,11357919 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,07323388 0,11350265 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,07323388 0,11342622 ! glycerol metabolic process GO:0006071 20 17 0,000 0,07323388 0,11334989 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,07323388 0,11327366 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,07323388 0,11319754 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,07323388 0,11312151 ! signal complex assembly GO:0007172 29 17 0,000 0,07323388 0,11304559 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,07323388 0,11296977 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,07323388 0,11289406 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,07323388 0,11281844 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,07323388 0,11274293 ! memory GO:0007613 25 17 0,000 0,07323388 0,11266751 ! keratinization GO:0031424 17 17 0,000 0,07323388 0,1125922 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,07323388 0,11251699 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,07323388 0,11244188 ! retinoid metabolic process GO:0001523 22 17 0,000 0,07323388 0,11236687 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,07323388 0,11229196 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,07323388 0,11221714 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,07323388 0,11214243 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,07323388 0,11206782 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,07323388 0,11199331 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,07323388 0,11191889 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,07323388 0,11184458 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,07323388 0,11177036 ! membrane budding GO:0006900 29 17 0,000 0,07323388 0,11169624 ! heme metabolic process GO:0042168 27 17 0,000 0,07323388 0,11162222 ! actin filament bundle formation GO:0051017 26 17 0,000 0,07323388 0,1115483 ! neuromuscular junction development GO:0007528 23 17 0,000 0,07323388 0,11147448 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,07323388 0,11140075 ! body fluid secretion GO:0007589 27 17 0,000 0,07323388 0,11132712 ! stem cell differentiation GO:0048863 36 17 0,000 0,07323388 0,11125359 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,07323388 0,11118015 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,07323388 0,11110682 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,07323388 0,11103358 ! sensory perception of pain GO:0019233 23 17 0,000 0,07323388 0,11096043 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,07323388 0,11088738 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,07323388 0,11081443 ! synaptogenesis GO:0007416 24 17 0,000 0,07323388 0,11074157 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,07323388 0,11066881 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,07323388 0,11059615 ! cell-cell junction organization GO:0045216 25 17 0,000 0,07323388 0,11052358 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,07323388 0,1104511 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,07323388 0,11037872 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,07323388 0,11030644 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,07323388 0,11023425 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,07323388 0,11016215 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,07323388 0,11009015 ! protein localization in organelle GO:0033365 161 100 1,000 0,07353019 0,11046338 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,07737289 0,11616035 ! positive regulation of translation GO:0045727 28 18 0,000 0,07737289 0,11608457 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,07737289 0,1160089 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,07737289 0,11593332 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,07737289 0,11585784 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,07737289 0,11578247 ! cAMP metabolic process GO:0046058 33 18 0,000 0,07737289 0,11570718 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,07737289 0,115632 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,07737289 0,11555692 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,07737289 0,11548193 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,07737289 0,11540704 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,07737289 0,11533224 ! pancreas development GO:0031016 26 18 0,000 0,07737289 0,11525754 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,07737289 0,11518294 ! glutamine metabolic process GO:0006541 23 18 0,000 0,07737289 0,11510844 ! response to retinoic acid GO:0032526 25 18 0,000 0,07737289 0,11503403 ! pigmentation during development GO:0048066 31 18 0,000 0,07737289 0,11495972 ! central nervous system neuron development GO:0021954 30 18 0,000 0,07737289 0,11488551 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,07737289 0,11481139 ! fucose metabolic process GO:0006004 26 18 0,000 0,07737289 0,11473736 ! response to fungus GO:0009620 19 18 0,000 0,07737289 0,11466343 ! peptide cross-linking GO:0018149 31 18 0,000 0,07737289 0,1145896 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,07737289 0,11451586 ! heart process GO:0003015 27 18 0,000 0,07737289 0,11444222 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,07737289 0,11436867 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,07737289 0,11429521 ! visual learning GO:0008542 35 18 0,000 0,07737289 0,11422185 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,07737289 0,11414859 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,07737289 0,11407542 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,07737289 0,11400234 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,07737289 0,11392935 ! vitamin transport GO:0051180 24 18 0,000 0,07737289 0,11385646 ! hormone transport GO:0009914 27 18 0,000 0,07737289 0,11378366 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,07737289 0,11371096 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,07737289 0,11363835 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,07737289 0,11356583 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,07737289 0,1134934 ! cell-cell recognition GO:0009988 20 18 0,000 0,07737289 0,11342106 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,07737289 0,11334882 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,07737289 0,11327667 ! regulation of glucose import GO:0046324 21 18 0,000 0,07737289 0,11320461 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,07737289 0,11313264 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,07737289 0,11306077 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,07737289 0,11298898 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,08149365 0,11893109 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,08149365 0,11885567 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,08149365 0,11878035 ! positive regulation of ossification GO:0045778 30 19 0,000 0,08149365 0,11870513 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,08149365 0,11863 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,08149365 0,11855496 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,08149365 0,11848002 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,08149365 0,11840518 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,08149365 0,11833042 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,08149365 0,11825577 ! regeneration GO:0031099 32 19 0,000 0,08149365 0,11818121 ! sensory perception of taste GO:0050909 23 19 0,000 0,08149365 0,11810674 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,08149365 0,11803236 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,08149365 0,11795808 ! smooth muscle contraction GO:0006939 36 19 0,000 0,08149365 0,11788389 ! peroxisome organization GO:0007031 29 19 0,000 0,08149365 0,1178098 ! digestive system process GO:0022600 30 19 0,000 0,08149365 0,1177358 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,08149365 0,11766189 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,08149365 0,11758808 ! response to vitamin A GO:0033189 26 19 0,000 0,08149365 0,11751435 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,08149365 0,11744072 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,08149365 0,11736718 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,08149365 0,11729374 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,08149365 0,11722038 ! cytolysis GO:0019835 20 19 0,000 0,08149365 0,11714712 ! renal system process GO:0003014 35 19 0,000 0,08149365 0,11707395 ! vasodilation GO:0042311 33 19 0,000 0,08149365 0,11700087 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,08149365 0,11692788 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,08149365 0,11685498 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,08149365 0,11678218 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,08149365 0,11670946 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,08149365 0,11663683 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,08149365 0,1165643 ! sarcomere organization GO:0045214 23 19 0,000 0,08149365 0,11649185 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,08149365 0,1164195 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,08149365 0,11634723 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,08149365 0,11627506 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,08149365 0,11620297 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,08149365 0,11613097 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,08149365 0,11605907 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,08149365 0,11598725 ! protein stabilization GO:0050821 26 19 0,000 0,08149365 0,11591552 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,08559624 0,12167574 ! iron ion transport GO:0006826 37 20 0,000 0,08559624 0,12160058 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,08559624 0,12152552 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,08559624 0,12145055 GO:0006044|N-acetylglucosamine metabolic process, ! response to vitamin GO:0033273 29 20 0,000 0,08559624 0,12137568 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,08559624 0,12130089 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,08559624 0,1212262 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,08559624 0,1211516 ! spinal cord development GO:0021510 31 20 0,000 0,08559624 0,12107709 ! response to ethanol GO:0045471 37 20 0,000 0,08559624 0,12100267 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,08559624 0,12092834 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,08559624 0,12085411 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,08559624 0,12077997 ! chromosome condensation GO:0030261 31 20 0,000 0,08559624 0,12070591 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,08559624 0,12063195 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,08559624 0,12055808 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,08559624 0,1204843 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,08559624 0,12041061 ! pallium development GO:0021543 38 20 0,000 0,08559624 0,12033701 ! DNA modification GO:0006304 28 20 0,000 0,08559624 0,1202635 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,08559624 0,12019008 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,08559624 0,12011674 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,08559624 0,1200435 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,08559624 0,11997035 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,08559624 0,11989729 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,08559624 0,11982431 ! collagen catabolic process GO:0030574 25 20 0,000 0,08559624 0,11975143 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,08559624 0,11967863 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,08559624 0,11960592 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,08559624 0,1195333 ! alditol metabolic process GO:0019400 24 20 0,000 0,08559624 0,11946077 ! actin filament-based movement GO:0030048 34 20 0,000 0,08559624 0,11938832 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,08968073 0,12500951 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,08968073 0,12493379 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,08968073 0,12485817 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,08968073 0,12478263 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,08968073 0,12470719 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,08968073 0,12463184 GO:0009799|determination of symmetry, ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,08968073 0,12455658 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,08968073 0,12448141 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,08968073 0,12440633 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,08968073 0,12433134 ! vesicle docking GO:0048278 27 21 0,000 0,08968073 0,12425644 ! phototransduction GO:0007602 25 21 0,000 0,08968073 0,12418163 ! dendrite development GO:0016358 35 21 0,000 0,08968073 0,12410691 ! visual behavior GO:0007632 39 21 0,000 0,08968073 0,12403228 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,08968073 0,12395775 ! ovarian follicle development GO:0001541 30 21 0,000 0,08968073 0,1238833 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,08968073 0,12380894 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,08968073 0,12373467 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,08968073 0,12366049 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,08968073 0,12358639 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,08968073 0,12351239 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,08968073 0,12343847 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,08968073 0,12336465 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,08968073 0,12329091 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,08968073 0,12321726 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,08968073 0,12314369 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,08968073 0,12307022 ! fatty acid transport GO:0015908 30 21 0,000 0,08968073 0,12299683 ! immunoglobulin production GO:0002377 33 21 0,000 0,08968073 0,12292353 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,08968073 0,12285032 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,08968073 0,1227772 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,08968073 0,12270416 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,08968073 0,12263121 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,08968073 0,12255834 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,08968073 0,12248556 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,08968073 0,12241287 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,08968073 0,12234027 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,08968073 0,12226775 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,08968073 0,12219531 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,08968073 0,12212297 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,08968073 0,1220507 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,08968073 0,12197853 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,08968073 0,12190644 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,09374722 0,12735889 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,09374722 0,12728371 ! viral genome replication GO:0019079 29 22 0,000 0,09374722 0,12720862 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,09374722 0,12713361 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,09374722 0,1270587 ! leukocyte adhesion GO:0007159 38 22 0,000 0,09374722 0,12698387 ! molting cycle process GO:0022404 40 22 0,000 0,09374722 0,12690913 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! glutamate signaling pathway GO:0007215 34 22 0,000 0,09374722 0,12683447 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,09374722 0,12675991 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,09374722 0,12668543 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,09374722 0,12661104 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,09374722 0,12653674 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,09374722 0,12646253 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,09374722 0,1263884 ! lysosome organization GO:0007040 37 22 0,000 0,09374722 0,12631436 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,09374722 0,1262404 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,09374722 0,12616653 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,09374722 0,12609275 ! regulation of behavior GO:0050795 38 22 0,000 0,09374722 0,12601906 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,09374722 0,12594545 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,09374722 0,12587192 ! membrane depolarization GO:0051899 35 22 0,000 0,09374722 0,12579849 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,09374722 0,12572513 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,09374722 0,12565187 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,09374722 0,12557869 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,09374722 0,12550559 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,09374722 0,12543258 ! neural tube closure GO:0001843 33 22 0,000 0,09374722 0,12535965 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,09374722 0,12528681 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,09779577 0,13062153 ! neuron fate commitment GO:0048663 32 23 0,000 0,09779577 0,13054572 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,09779577 0,13047 ! myelination GO:0042552 35 23 0,000 0,09779577 0,13039436 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,09779577 0,13031882 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,09779577 0,13024336 ! vesicle targeting GO:0006903 32 23 0,000 0,09779577 0,13016798 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,09779577 0,1300927 ! osteoblast differentiation GO:0001649 40 23 0,000 0,09779577 0,1300175 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,09779577 0,12994239 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,09779577 0,12986736 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,09779577 0,12979243 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,09779577 0,12971757 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,09779577 0,12964281 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,09779577 0,12956813 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,09779577 0,12949354 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,09779577 0,12941903 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,09779577 0,12934461 ! cell fate determination GO:0001709 45 23 0,000 0,09779577 0,12927027 ! pentose metabolic process GO:0019321 31 23 0,000 0,09779577 0,12919602 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,09779577 0,12912186 ! spermatid development GO:0007286 33 23 0,000 0,09779577 0,12904778 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,09779577 0,12897378 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,09779577 0,12889987 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,09779577 0,12882605 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,09779577 0,1287523 ! telomere organization GO:0032200 32 23 0,000 0,09779577 0,12867865 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,09779577 0,12860507 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,09779577 0,12853159 ! regulation of amine transport GO:0051952 38 23 0,000 0,09779577 0,12845818 ! liver development GO:0001889 40 23 0,000 0,09779577 0,12838486 ! initiation of viral infection GO:0019059 42 24 0,000 0,10182647 0,13360004 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,10182647 0,13352388 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,10182647 0,13344779 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,10182647 0,1333718 ! fat cell differentiation GO:0045444 37 24 0,000 0,10182647 0,13329589 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,10182647 0,13322007 ! sperm motility GO:0030317 27 24 0,000 0,10182647 0,13314433 ! vacuole organization GO:0007033 39 24 0,000 0,10182647 0,13306868 ! receptor metabolic process GO:0043112 37 24 0,000 0,10182647 0,13299312 ! neural crest cell development GO:0014032 39 24 0,000 0,10182647 0,13291764 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,10182647 0,13284224 ! primary neural tube formation GO:0014020 35 24 0,000 0,10182647 0,13276694 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,10182647 0,13269171 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,10182647 0,13261658 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,10182647 0,13254153 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,10182647 0,13246656 ! glutathione metabolic process GO:0006749 29 24 0,000 0,10182647 0,13239168 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,10182647 0,13231688 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,10182647 0,13224217 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,10182647 0,13216754 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,10583939 0,1372987 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,10583939 0,1372213 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,10583939 0,13714399 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,10583939 0,13706677 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,10583939 0,13698964 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,10583939 0,13691259 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,10583939 0,13683563 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,10583939 0,13675876 ! peptide transport GO:0015833 43 25 0,000 0,10583939 0,13668197 ! male gonad development GO:0008584 33 25 0,000 0,10583939 0,13660527 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,10583939 0,13652865 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,10583939 0,13645212 ! phospholipid transport GO:0015914 35 25 0,000 0,10583939 0,13637568 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,10583939 0,13629932 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,10583939 0,13622305 ! detection of light stimulus GO:0009583 30 25 0,000 0,10583939 0,13614686 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,10583939 0,13607076 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,10583939 0,13599474 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,10583939 0,13591881 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,10983461 0,14097075 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,10983461 0,14089213 ! translational initiation GO:0006413 43 26 0,000 0,10983461 0,1408136 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,10983461 0,14073515 ! circadian rhythm GO:0007623 42 26 0,000 0,10983461 0,14065679 ! post-embryonic development GO:0009791 42 26 0,000 0,10983461 0,14057852 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,10983461 0,14050033 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,10983461 0,14042223 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,10983461 0,14034422 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,10983461 0,14026629 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,10983461 0,14018845 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,10983461 0,1401107 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,10983461 0,14003303 ! regulation of coagulation GO:0050818 39 26 0,000 0,10983461 0,13995545 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,1138122 0,14494356 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,1138122 0,14486334 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,1138122 0,14478322 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,1138122 0,14470318 ! membrane docking GO:0022406 39 27 0,000 0,1138122 0,14462324 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,1138122 0,14454338 ! catechol metabolic process GO:0009712 43 27 0,000 0,1138122 0,14446361 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,1138122 0,14438393 ! acute-phase response GO:0006953 42 27 0,000 0,1138122 0,14430433 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,1138122 0,14422483 ! myofibril assembly GO:0030239 36 27 0,000 0,1138122 0,14414541 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,1138122 0,14406608 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,1138122 0,14398683 ! natural killer cell activation GO:0030101 35 27 0,000 0,1138122 0,14390768 ! lipid oxidation GO:0034440 38 27 0,000 0,1138122 0,14382861 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,1138122 0,14374962 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,1138122 0,14367073 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,1138122 0,14359192 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,1138122 0,14351319 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,1138122 0,14343455 ! gene silencing GO:0016458 41 27 0,000 0,1138122 0,143356 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,11777225 0,14826282 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,11777225 0,14818171 ! phenol metabolic process GO:0018958 44 28 0,000 0,11777225 0,1481007 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,11777225 0,14801977 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,11777225 0,14793893 ! cell junction assembly GO:0034329 56 28 0,000 0,11777225 0,14785817 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,11777225 0,14777751 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,11777225 0,14769693 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,11777225 0,14761644 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,11777225 0,14753604 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,11777225 0,14745573 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,11777225 0,1473755 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,11777225 0,14729536 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,11777225 0,14721531 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,11777225 0,14713535 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,11777225 0,14705547 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,11777225 0,14697568 ! mesoderm formation GO:0001707 46 28 0,000 0,11777225 0,14689597 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,11777225 0,14681635 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,11777225 0,14673682 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,11777225 0,14665738 ! ensheathment of neurons GO:0007272 43 28 0,000 0,11777225 0,14657802 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,11777225 0,14649874 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,11777225 0,14641955 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,11777225 0,14634045 ! neural tube formation GO:0001841 41 28 0,000 0,11777225 0,14626143 ! regulation of B cell activation GO:0050864 42 28 0,000 0,11777225 0,1461825 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,12171483 0,15099466 ! regulation of innate immune response GO:0045088 38 29 0,000 0,12171483 0,15091326 ! ovulation cycle process GO:0022602 41 29 0,000 0,12171483 0,15083195 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,12171483 0,15075073 ! protein targeting to membrane GO:0006612 53 29 0,000 0,12171483 0,15066959 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,12171483 0,15058854 ! mismatch repair GO:0006298 34 29 0,000 0,12171483 0,15050758 ! muscle cell development GO:0055001 38 29 0,000 0,12171483 0,15042671 ! formation of primary germ layer GO:0001704 48 29 0,000 0,12171483 0,15034592 ! telencephalon development GO:0021537 52 29 0,000 0,12171483 0,15026522 ! eye morphogenesis GO:0048592 51 29 0,000 0,12171483 0,1501846 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,12171483 0,15010408 ! tissue homeostasis GO:0001894 42 29 0,000 0,12171483 0,15002364 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,12564001 0,1547788 ! collagen metabolic process GO:0032963 40 30 0,000 0,12564001 0,15469595 ! organic anion transport GO:0015711 51 30 0,000 0,12564001 0,15461318 ! cholesterol transport GO:0030301 46 30 0,000 0,12564001 0,1545305 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,12564001 0,1544479 ! spliceosome assembly GO:0000245 49 30 0,000 0,12564001 0,1543654 ! spindle organization GO:0007051 37 30 0,000 0,12564001 0,15428298 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,12564001 0,15420066 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,12564001 0,15411841 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,12564001 0,15403626 ! ceramide metabolic process GO:0006672 43 30 0,000 0,12564001 0,1539542 ! ovulation cycle GO:0042698 43 30 0,000 0,12564001 0,15387222 ! hindbrain development GO:0030902 45 30 0,000 0,12564001 0,15379033 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,12564001 0,15370853 ! adult locomotory behavior GO:0008344 47 30 0,000 0,12564001 0,15362681 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,12564001 0,15354518 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,12564001 0,15346364 ! response to heat GO:0009408 41 30 0,000 0,12564001 0,15338218 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,12564001 0,15330081 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,12564001 0,15321953 ! negative regulation of secretion GO:0051048 49 31 0,000 0,12954788 0,15790149 ! mammary gland development GO:0030879 57 31 0,000 0,12954788 0,15781786 ! glial cell differentiation GO:0010001 55 31 0,000 0,12954788 0,15773431 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,12954788 0,15765086 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,12954788 0,15756749 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,12954788 0,15748421 ! odontogenesis GO:0042476 50 31 0,000 0,12954788 0,15740101 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,12954788 0,15731791 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,12954788 0,15723489 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,12954788 0,15715196 ! metanephros development GO:0001656 58 31 0,000 0,12954788 0,15706912 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,12954788 0,15698636 ! cell fate specification GO:0001708 37 31 0,000 0,12954788 0,1569037 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,12954788 0,15682112 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,12954788 0,15673862 ! RNA modification GO:0009451 40 31 0,000 0,12954788 0,15665621 ! regulation of muscle development GO:0048634 48 32 0,000 0,1334385 0,16127617 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,1334385 0,16119147 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,1334385 0,16110685 ! meiosis I GO:0007127 52 32 0,000 0,1334385 0,16102233 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,1334385 0,16093789 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,1334385 0,16085354 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,1334385 0,16076928 GO:0006639|acylglycerol metabolic process, ! peripheral nervous system development GO:0007422 53 32 0,000 0,1334385 0,16068511 ! regulation of protein stability GO:0031647 48 32 0,000 0,1334385 0,16060102 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,1334385 0,16051703 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,1334385 0,16043312 ! cytokine production GO:0001816 44 32 0,000 0,1334385 0,1603493 ! vesicle localization GO:0051648 47 32 0,000 0,1334385 0,16026556 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,13731196 0,16483168 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,13731196 0,1647457 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,13731196 0,1646598 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,13731196 0,164574 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,13731196 0,16448828 ! sister chromatid segregation GO:0000819 46 33 0,000 0,13731196 0,16440266 ! actomyosin structure organization GO:0031032 43 33 0,000 0,13731196 0,16431712 ! cell junction organization GO:0034330 63 33 0,000 0,13731196 0,16423167 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,13731196 0,16414631 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,13731196 0,16406104 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,13731196 0,16397586 ! female gonad development GO:0008585 49 33 0,000 0,13731196 0,16389076 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,13731196 0,16380576 ! positive regulation of cell development GO:0010720 54 33 0,000 0,13731196 0,16372084 ! lipid homeostasis GO:0055088 55 33 0,000 0,13731196 0,16363601 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,13731196 0,16355127 ! regulation of proteolysis GO:0030162 50 33 0,000 0,13731196 0,16346662 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,13731196 0,16338205 ! cytokinesis GO:0000910 52 33 0,000 0,13731196 0,16329757 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,13731196 0,16321318 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,14116832 0,1677103 ! mRNA catabolic process GO:0006402 48 34 0,000 0,14116832 0,16762371 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,14116832 0,16753722 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,14116832 0,16745082 ! feeding behavior GO:0007631 45 34 0,000 0,14116832 0,1673645 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,14116832 0,16727828 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,14116832 0,16719214 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,14116832 0,16710609 ! neuron migration GO:0001764 46 34 0,000 0,14116832 0,16702013 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,14116832 0,16693426 ! female gamete generation GO:0007292 43 34 0,000 0,14116832 0,16684848 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,14116832 0,16676278 ! polyol metabolic process GO:0019751 44 34 0,000 0,14116832 0,16667717 ! aerobic respiration GO:0009060 47 34 0,000 0,14116832 0,16659165 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,14116832 0,16650622 ! embryonic organ development GO:0048568 45 34 0,000 0,14116832 0,16642088 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,14116832 0,16633562 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,14500766 0,17077195 ! Notch signaling pathway GO:0007219 56 35 0,000 0,14500766 0,17068456 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,14500766 0,17059725 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,14500766 0,17051003 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,14500766 0,1704229 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,14500766 0,17033587 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,14500766 0,17024892 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,14500766 0,17016205 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,14500766 0,17007528 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,14500766 0,1699886 ! pigment metabolic process GO:0042440 61 35 0,000 0,14500766 0,169902 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,14500766 0,16981549 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,14500766 0,16972907 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,14883006 0,17411452 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,14883006 0,174026 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,14883006 0,17393757 ! negative regulation of binding GO:0051100 58 36 0,000 0,14883006 0,17384923 ! organic ether metabolic process GO:0018904 46 36 0,000 0,14883006 0,17376099 ! neural tube development GO:0021915 50 36 0,000 0,14883006 0,17367283 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,14883006 0,17358476 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,14883006 0,17349678 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,14883006 0,17340889 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,14883006 0,17332109 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,15263559 0,17766288 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,15263559 0,17757302 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,15263559 0,17748325 ! learning GO:0007612 67 37 0,000 0,15263559 0,17739356 ! ion transmembrane transport GO:0034220 56 37 0,000 0,15263559 0,17730397 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,15263559 0,17721447 ! regulation of protein secretion GO:0050708 51 37 0,000 0,15263559 0,17712506 ! amino acid activation GO:0043038 52 37 0,000 0,15263559 0,17703573 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,15263559 0,1769465 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,15642432 0,18124733 ! gliogenesis GO:0042063 71 38 0,000 0,15642432 0,18115606 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,15642432 0,18106489 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,15642432 0,18097381 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,15642432 0,18088283 ! phagocytosis GO:0006909 60 38 0,000 0,15642432 0,18079193 ! mesenchymal cell development GO:0014031 64 38 0,000 0,15642432 0,18070113 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 0,000 0,15642432 0,18061041 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,16019633 0,18487284 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,16019633 0,18478012 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,16019633 0,1846875 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,16019633 0,18459497 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,16019633 0,18450253 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,16019633 0,18441019 ! male sex differentiation GO:0046661 53 39 0,000 0,16019633 0,18431794 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,16019633 0,18422578 ! chromatin remodeling GO:0006338 68 39 0,000 0,16019633 0,18413371 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,16019633 0,18404174 ! JNK cascade GO:0007254 54 39 0,000 0,16019633 0,18394986 ! developmental growth GO:0048589 62 39 0,000 0,16019633 0,18385806 ! cell growth GO:0016049 61 39 0,000 0,16019633 0,18376636 ! synapse organization GO:0050808 55 39 0,000 0,16019633 0,18367476 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,16395169 0,18788684 ! response to calcium ion GO:0051592 58 40 0,000 0,16395169 0,18779327 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,16395169 0,18769979 ! regulation of tube size GO:0035150 60 40 0,000 0,16395169 0,18760641 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,16395169 0,18751312 ! peptide metabolic process GO:0006518 56 40 0,000 0,16395169 0,18741992 ! inner ear development GO:0048839 57 40 0,000 0,16395169 0,18732682 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,16395169 0,1872338 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,16395169 0,18714088 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,16395169 0,18704806 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,16395169 0,18695532 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,16769047 0,19112392 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,16769047 0,19102926 ! glucose transport GO:0015758 52 41 0,000 0,16769047 0,19093469 ! endosome transport GO:0016197 71 41 0,000 0,16769047 0,19084021 ! striated muscle contraction GO:0006941 62 41 0,000 0,16769047 0,19074583 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,16769047 0,19065154 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,16769047 0,19055735 ! biopolymer methylation GO:0043414 62 41 0,000 0,16769047 0,19046324 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,16769047 0,19036924 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,17141274 0,19449891 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,17141274 0,19440301 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,17141274 0,19430719 ! hexose transport GO:0008645 54 42 0,000 0,17141274 0,19421148 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,17141274 0,19411585 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,17141274 0,19402032 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,17141274 0,19392489 ! excretion GO:0007588 63 42 0,000 0,17141274 0,19382955 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,17141274 0,1937343 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,17141274 0,19363914 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,17141274 0,19354408 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,17511857 0,19763136 ! leukocyte migration GO:0050900 60 43 0,000 0,17511857 0,19753444 ! neuromuscular process GO:0050905 79 43 0,000 0,17511857 0,19743761 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,17511857 0,19734087 ! tRNA processing GO:0008033 49 43 0,000 0,17511857 0,19724423 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,17511857 0,19714769 ! vesicle organization GO:0016050 79 43 0,000 0,17511857 0,19705123 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,17511857 0,19695488 ! methylation GO:0032259 64 43 0,000 0,17511857 0,19685861 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,17880805 0,20090792 ! glycolysis GO:0006096 53 44 0,000 0,17880805 0,20080982 ! regulation of action potential GO:0001508 71 44 0,000 0,17880805 0,20071182 ! regulation of ion transport GO:0043269 57 44 0,000 0,17880805 0,20061391 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,17880805 0,2005161 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,17880805 0,20041838 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,17880805 0,20032076 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,17880805 0,20022323 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,17880805 0,2001258 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,17880805 0,20002846 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,17880805 0,19993122 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,18248123 0,20393918 ! RNA catabolic process GO:0006401 64 45 0,000 0,18248123 0,20384013 ! positive regulation of defense response GO:0031349 59 45 0,000 0,18248123 0,20374118 ! regulation of translational initiation GO:0006446 64 45 0,000 0,18248123 0,20364233 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,18248123 0,20354357 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,18248123 0,2034449 ! cell recognition GO:0008037 58 45 0,000 0,18248123 0,20334634 ! cell maturation GO:0048469 60 45 0,000 0,18248123 0,20324786 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,1861382 0,20722064 ! cell redox homeostasis GO:0045454 63 46 0,000 0,1861382 0,20712039 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,1861382 0,20702024 ! regulation of ossification GO:0030278 71 46 0,000 0,1861382 0,20692018 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,1861382 0,20682022 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,18977901 0,21076375 ! viral infectious cycle GO:0019058 71 47 0,000 0,18977901 0,21066203 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,18977901 0,21056041 ! endocrine system development GO:0035270 83 47 0,000 0,18977901 0,21045888 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,18977901 0,21035746 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,18977901 0,21025613 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,18977901 0,2101549 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,18977901 0,21005376 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,18977901 0,20995273 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 0,000 0,18977901 0,20985179 ! chloride transport GO:0006821 67 48 0,000 0,19340374 0,21375714 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,19340374 0,21365447 ! response to temperature stimulus GO:0009266 62 48 0,000 0,19340374 0,2135519 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,19340374 0,21344943 ! gastrulation GO:0007369 73 48 0,000 0,19340374 0,21334705 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,19340374 0,21324478 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,19340374 0,2131426 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,19340374 0,21304052 ! regulation of endocytosis GO:0030100 63 48 0,000 0,19340374 0,21293854 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,19340374 0,21283666 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,19340374 0,21273487 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,19701247 0,21660071 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,19701247 0,21649722 ! sensory perception of smell GO:0007608 61 49 0,000 0,19701247 0,21639383 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,19701247 0,21629054 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,19701247 0,21618735 ! RNA elongation GO:0006354 62 49 0,000 0,19701247 0,21608425 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,19701247 0,21598126 ! germ cell development GO:0007281 68 49 0,000 0,19701247 0,21587836 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,19701247 0,21577556 ! cartilage development GO:0051216 70 49 0,000 0,19701247 0,21567286 ! maintenance of location GO:0051235 84 49 0,000 0,19701247 0,21557026 ! regulation of actin filament length GO:0030832 72 50 0,000 0,20060525 0,21939709 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,20060525 0,21929282 ! proton transport GO:0015992 75 50 0,000 0,20060525 0,21918864 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,20060525 0,21908456 ! positive regulation of secretion GO:0051047 71 51 0,000 0,20418217 0,22288514 ! hydrogen transport GO:0006818 77 51 0,000 0,20418217 0,22277941 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,20418217 0,22267377 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,20418217 0,22256824 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,20418217 0,22246281 ! adult behavior GO:0030534 80 51 0,000 0,20418217 0,22235748 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,20418217 0,22225224 ! transition metal ion transport GO:0000041 74 52 0,000 0,20774328 0,22602155 ! regulation of cellular component size GO:0032535 74 52 0,000 0,20774328 0,22591468 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,20774328 0,22580792 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,20774328 0,22570125 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,21128867 0,22944473 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,21128867 0,22933645 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,21128867 0,22922827 ! kidney development GO:0001822 90 53 0,000 0,21128867 0,22912019 ! single fertilization GO:0007338 59 53 0,000 0,21128867 0,22901222 ! amino acid transport GO:0006865 84 54 0,000 0,21481839 0,23272835 ! regulation of mitosis GO:0007088 84 54 0,000 0,21481839 0,23261878 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,21481839 0,23250931 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,21481839 0,23239995 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,21481839 0,23229069 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,21481839 0,23218153 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,21481839 0,23207247 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,21481839 0,23196352 ! mesoderm development GO:0007498 76 55 0,000 0,21833251 0,23564748 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,21833251 0,23553695 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,21833251 0,23542652 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,22183111 0,23908695 ! carbohydrate transport GO:0008643 74 57 0,000 0,22531425 0,24272729 ! chromosome segregation GO:0007059 83 57 0,000 0,22531425 0,24261366 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,22531425 0,24250013 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,22531425 0,2423867 ! camera-type eye development GO:0043010 88 57 0,000 0,22531425 0,24227338 ! secondary metabolic process GO:0019748 84 57 0,000 0,22531425 0,24216017 ! developmental maturation GO:0021700 75 57 0,000 0,22531425 0,24204707 ! gonad development GO:0008406 79 57 0,000 0,22531425 0,24193407 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,22878199 0,24554297 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,22878199 0,24542845 ! actin filament organization GO:0007015 95 59 0,000 0,23223442 0,24901592 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,23223442 0,24889989 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,23567158 0,25246606 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,23567158 0,25234853 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,23567158 0,2522311 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,23567158 0,25211378 ! regulation of heart contraction GO:0008016 91 60 0,000 0,23567158 0,25199658 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,23567158 0,25187948 ! fertilization GO:0009566 68 60 0,000 0,23567158 0,25176249 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,23909355 0,25529952 ! meiosis GO:0007126 96 61 0,000 0,23909355 0,25518106 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,23909355 0,2550627 ! urogenital system development GO:0001655 101 61 0,000 0,23909355 0,25494445 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,23909355 0,25482631 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,23909355 0,25470828 ! extracellular matrix organization GO:0030198 103 61 0,000 0,23909355 0,25459036 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,23909355 0,25447255 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,23909355 0,25435484 ! amine catabolic process GO:0009310 90 62 0,000 0,2425004 0,25785988 ! neurotransmitter transport GO:0006836 81 62 0,000 0,2425004 0,25774072 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,2425004 0,25762167 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,2425004 0,25750274 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,2425004 0,25738391 ! meiotic cell cycle GO:0051321 97 62 0,000 0,2425004 0,25726519 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,24589219 0,26074322 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,24589219 0,26062306 ! regulation of lipase activity GO:0060191 109 63 0,000 0,24589219 0,26050301 ! appendage morphogenesis GO:0035107 93 64 0,000 0,24926899 0,26395887 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,24926899 0,2638374 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,24926899 0,26371604 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,24926899 0,26359479 ! hexose catabolic process GO:0019320 82 64 0,000 0,24926899 0,26347365 ! adaptive immune response GO:0002250 94 64 0,000 0,24926899 0,26335263 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,25263086 0,2667819 ! appendage development GO:0048736 94 65 0,000 0,25263086 0,26665946 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,25263086 0,26653714 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,25263086 0,26641493 ! defense response to bacterium GO:0042742 73 65 0,000 0,25263086 0,26629284 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,25263086 0,26617085 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,25263086 0,26604898 ! activation of immune response GO:0002253 83 65 0,000 0,25263086 0,26592722 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,25597786 0,26932712 ! antigen processing and presentation GO:0019882 96 66 0,000 0,25597786 0,26920397 ! axon guidance GO:0007411 99 66 0,000 0,25597786 0,26908093 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,25597786 0,26895801 ! regulation of immune effector process GO:0002697 101 66 0,000 0,25597786 0,2688352 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,25931007 0,27221048 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,25931007 0,27208629 ! acute inflammatory response GO:0002526 92 68 0,000 0,26262754 0,27544156 ! learning or memory GO:0007611 123 68 0,000 0,26262754 0,27531602 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,26262754 0,27519059 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,26262754 0,27506528 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,26262754 0,27494008 ! rhythmic process GO:0048511 105 68 0,000 0,26262754 0,27481499 ! inorganic anion transport GO:0015698 93 68 0,000 0,26262754 0,27469002 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,26593035 0,27801809 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,26593035 0,27789178 ! response to metal ion GO:0010038 103 70 0,000 0,26921855 0,28120012 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,26921855 0,28107247 ! humoral immune response GO:0006959 86 70 0,000 0,26921855 0,28094495 ! eye development GO:0001654 111 70 0,000 0,26921855 0,28081753 ! amine transport GO:0015837 101 70 0,000 0,26921855 0,28069024 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,26921855 0,28056305 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,26921855 0,28043599 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,27249221 0,28371755 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,27249221 0,28358918 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,27249221 0,28346091 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,27249221 0,28333277 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,27249221 0,28320473 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,27575139 0,2864626 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,27575139 0,28633327 ! regulation of blood pressure GO:0008217 107 73 0,000 0,27899616 0,28957182 ! tube morphogenesis GO:0035239 118 73 0,000 0,27899616 0,28944121 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,27899616 0,28931071 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,27899616 0,28918033 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,28222657 0,2923969 ! digestion GO:0007586 97 74 0,000 0,28222657 0,29226525 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,28222657 0,29213371 ! blood coagulation GO:0007596 116 75 0,000 0,2854427 0,29532983 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,2854427 0,29519703 ! response to nutrient GO:0007584 104 75 0,000 0,2854427 0,29506436 ! regulation of ligase activity GO:0051340 114 75 0,000 0,2854427 0,29493181 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,2854427 0,29479937 ! amine biosynthetic process GO:0009309 97 76 0,000 0,2886446 0,29797243 ! tRNA metabolic process GO:0006399 95 76 0,000 0,2886446 0,29783875 ! response to unfolded protein GO:0006986 99 76 0,000 0,2886446 0,29770519 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,29183233 0,30085807 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,29183233 0,30072328 ! gland development GO:0048732 148 77 0,000 0,29183233 0,30058861 ! sex differentiation GO:0007548 105 77 0,000 0,29183233 0,30045406 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,29183233 0,30031963 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,29183233 0,30018532 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,29500597 0,30331414 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,29500597 0,30317861 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,29500597 0,3030432 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,29816556 0,30615213 ! cellular respiration GO:0045333 107 79 0,000 0,29816556 0,30601552 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,29816556 0,30587903 ! regulation of lyase activity GO:0051339 133 79 0,000 0,29816556 0,30574266 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,29816556 0,30560641 ! chromatin assembly GO:0031497 102 80 0,000 0,30131117 0,30869296 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,30131117 0,30855552 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,30131117 0,3084182 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,30131117 0,308281 ! forebrain development GO:0030900 131 80 0,000 0,30131117 0,30814393 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,30444286 0,31120826 ! hemostasis GO:0007599 125 81 0,000 0,30444286 0,31107001 ! response to protein stimulus GO:0051789 111 81 0,000 0,30444286 0,31093188 ! regulation of neurological system process GO:0031644 122 81 0,000 0,30444286 0,31079387 ! vitamin metabolic process GO:0006766 103 81 0,000 0,30444286 0,31065598 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,30444286 0,31051822 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,3075607 0,31355922 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,31066474 0,31658347 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,31066474 0,31644327 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,31066474 0,31630318 ! regulation of defense response GO:0031347 117 84 0,000 0,31375504 0,31930822 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,31375504 0,319167 ! sterol metabolic process GO:0016125 120 84 0,000 0,31375504 0,3190259 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,31683166 0,32201185 ! rRNA metabolic process GO:0016072 107 85 0,000 0,31683166 0,32186962 GO:0006364|rRNA processing, ! regulation of membrane potential GO:0042391 128 85 0,000 0,31683166 0,32172752 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,31683166 0,32158553 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,31989467 0,32455127 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,31989467 0,32440817 ! nucleosome organization GO:0034728 114 87 0,000 0,32294412 0,32735631 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,32294412 0,3272121 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,32598007 0,33014274 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,32598007 0,32999743 ! interphase GO:0051325 159 88 0,000 0,32598007 0,32985225 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,32598007 0,32970719 GO:0016054|organic acid catabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,32900258 0,33261799 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,32900258 0,33247185 ! regulation of T cell activation GO:0050863 128 89 0,000 0,32900258 0,33232584 ! hormone metabolic process GO:0042445 121 90 0,000 0,33201171 0,33521814 ! ATP metabolic process GO:0046034 137 91 0,000 0,33500752 0,33809447 ! response to virus GO:0009615 122 91 0,000 0,33500752 0,33794618 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,33799006 0,34080541 ! positive regulation of immune response GO:0050778 121 92 0,000 0,33799006 0,34065606 ! DNA recombination GO:0006310 146 92 0,000 0,33799006 0,34050685 ! sulfur metabolic process GO:0006790 118 92 0,000 0,33799006 0,34035777 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,3409594 0,34319764 ! electron transport chain GO:0022900 123 94 0,000 0,34391559 0,34602181 ! response to oxidative stress GO:0006979 141 94 0,000 0,34391559 0,34587051 ! carboxylic acid transport GO:0046942 147 95 0,000 0,34685868 0,34867787 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,34978875 0,35146969 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,35270584 0,35424604 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,35270584 0,35409141 ! calcium ion transport GO:0006816 167 99 0,000 0,35850131 0,35975262 ! extracellular structure organization GO:0043062 156 99 0,000 0,35850131 0,35959573 ! regulation of translation GO:0006417 151 100 0,000 0,3613798 0,362325 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,3613798 0,36216712 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,3613798 0,36200938 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,3613798 0,36185178 ! divalent metal ion transport GO:0070838 171 100 0,000 0,3613798 0,36169432 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,3613798 0,36153699 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,3613798 0,3613798