pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1145-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 12 6 2,000 1,048E-06 2,521E-03 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 1,048E-06 1,26E-03 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipid kinase activity GO:0043550 13 7 2,000 1,828E-06 1,466E-03 ! macrophage differentiation GO:0030225 11 7 2,000 1,828E-06 1,1E-03 ! ER overload response GO:0006983 12 8 2,000 2,917E-06 1,404E-03 ! establishment of nucleus localization GO:0040023 16 8 2,000 2,917E-06 1,17E-03 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 2,000 6,217E-06 2,137E-03 GO:0007520|myoblast fusion, ! syncytium formation GO:0006949 18 11 2,000 8,525E-06 2,564E-03 ! nucleus localization GO:0051647 19 11 2,000 8,525E-06 2,279E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 1,133E-05 2,727E-03 ! myotube differentiation GO:0014902 25 14 2,000 1,865E-05 4,079E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 1,865E-05 3,739E-03 ! filopodium assembly GO:0046847 32 16 2,000 2,854E-05 5,281E-03 ! microspike assembly GO:0030035 36 17 2,000 3,455E-05 5,938E-03 ! plasma membrane fusion GO:0045026 28 19 2,000 4,897E-05 7,855E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 5,745E-05 8,639E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 7,718E-05 0,01092362 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 8,852E-05 0,01183156 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 9,763E-05 0,01236312 ! protein tetramerization GO:0051262 52 24 2,000 1,009E-04 0,01213607 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 1,143E-04 0,01309809 ! interaction with host GO:0051701 62 25 2,000 1,143E-04 0,01250272 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 1,289E-04 0,01348177 ! phospholipid dephosphorylation GO:0046839 12 5 1,000 1,41E-04 0,0141327 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,41E-04 0,0135674 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,41E-04 0,01304557 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,41E-04 0,0125624 ! decidualization GO:0046697 11 5 1,000 1,41E-04 0,01211375 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 1,446E-04 0,01199586 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,615E-04 0,01295175 ! regulation of caspase activity GO:0043281 122 72 3,000 1,643E-04 0,012749 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 1,796E-04 0,01350601 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 1,796E-04 0,01309674 ! exocytosis GO:0006887 133 74 3,000 1,827E-04 0,01292532 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 1,827E-04 0,01255602 ! male sex determination GO:0030238 15 6 1,000 2,109E-04 0,01409769 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2,109E-04 0,01371667 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 2,109E-04 0,01335571 ! maternal placenta development GO:0001893 12 6 1,000 2,109E-04 0,01301326 ! regulation of peptidase activity GO:0052547 134 79 3,000 2,351E-04 0,01413938 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 2,901E-04 0,01702675 ! regulation of helicase activity GO:0051095 15 7 1,000 2,946E-04 0,01687534 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,946E-04 0,01648289 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,946E-04 0,01610827 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 2,946E-04 0,01575031 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 2,946E-04 0,01540791 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,946E-04 0,01508009 ! B cell lineage commitment GO:0002326 21 7 1,000 2,946E-04 0,01476592 ! T cell lineage commitment GO:0002360 16 7 1,000 2,946E-04 0,01446457 ! response to tumor cell GO:0002347 13 7 1,000 2,946E-04 0,01417528 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,946E-04 0,01389733 ! positive regulation of ATPase activity GO:0032781 11 7 1,000 2,946E-04 0,01363008 ! regulation of microtubule-based process GO:0032886 78 35 2,000 3,165E-04 0,01436685 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 3,443E-04 0,01534038 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 3,736E-04 0,01634535 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 3,736E-04 0,01605347 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 3,918E-04 0,01653823 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,918E-04 0,01625309 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 3,918E-04 0,01597761 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 3,918E-04 0,01571132 ! leukocyte differentiation GO:0002521 202 96 3,000 4,947E-04 0,01951236 ! regulation of developmental growth GO:0048638 15 9 1,000 5,025E-04 0,01950026 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 5,025E-04 0,01919073 ! regulation of glycolysis GO:0006110 21 9 1,000 5,025E-04 0,01889088 ! middle ear morphogenesis GO:0042474 14 9 1,000 5,025E-04 0,01860025 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 5,025E-04 0,01831843 ! protein heterooligomerization GO:0051291 16 9 1,000 5,025E-04 0,01804502 ! regulation of telomere maintenance GO:0032204 14 9 1,000 5,025E-04 0,01777965 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 5,145E-04 0,01793989 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 5,445E-04 0,01871558 ! skeletal muscle tissue development GO:0007519 186 99 3,000 5,557E-04 0,01883223 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 3,000 5,772E-04 0,01928845 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 6,266E-04 0,0206511 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 6,266E-04 0,02037203 ! DNA ligation GO:0006266 19 10 1,000 6,266E-04 0,02010041 ! protein sumoylation GO:0016925 15 10 1,000 6,266E-04 0,01983593 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 6,266E-04 0,01957832 GO:0043470|regulation of carbohydrate catabolic process, ! blastocyst formation GO:0001825 17 10 1,000 6,266E-04 0,01932731 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 6,675E-04 0,02032971 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 7,121E-04 0,02141724 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 7,121E-04 0,02115283 ! response to insulin stimulus GO:0032868 95 46 2,000 7,121E-04 0,02089487 ! positive regulation of DNA binding GO:0043388 73 47 2,000 7,586E-04 0,02199007 ! respiratory burst GO:0045730 17 11 1,000 7,639E-04 0,02188071 ! detection of mechanical stimulus GO:0050982 22 11 1,000 7,639E-04 0,02162329 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 7,639E-04 0,02137185 ! regulation of intracellular pH GO:0051453 19 11 1,000 7,639E-04 0,0211262 ! embryonic axis specification GO:0000578 18 11 1,000 7,639E-04 0,02088613 ! germ cell migration GO:0008354 25 11 1,000 7,639E-04 0,02065145 ! regulation of embryonic development GO:0045995 27 11 1,000 7,639E-04 0,02042199 ! activation of caspase activity GO:0006919 84 48 2,000 8,069E-04 0,02133528 ! regulation of cell projection organization GO:0031344 121 50 2,000 9,094E-04 0,02378348 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 9,144E-04 0,02365721 ! virus-host interaction GO:0019048 29 12 1,000 9,144E-04 0,02340554 ! entry into host cell GO:0030260 32 12 1,000 9,144E-04 0,02315917 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 9,144E-04 0,02291793 ! peptidyl-lysine modification GO:0018205 21 12 1,000 9,144E-04 0,02268166 ! positive regulation of binding GO:0051099 78 51 2,000 9,636E-04 0,02365772 ! regulation of cell shape GO:0008360 125 51 2,000 9,636E-04 0,02341876 ! membrane fusion GO:0006944 110 52 2,000 1,02E-03 0,02453654 ! response to X-ray GO:0010165 25 13 1,000 1,078E-03 0,02568034 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,078E-03 0,02542858 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,078E-03 0,0251817 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 1,078E-03 0,02493956 ! regulation of calcium-mediated signaling GO:0050848 25 13 1,000 1,078E-03 0,02470204 ! embryonic placenta development GO:0001892 23 13 1,000 1,078E-03 0,02446901 ! positive regulation of caspase activity GO:0043280 95 55 2,000 1,201E-03 0,02699857 GO:0010952|positive regulation of peptidase activity, ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,255E-03 0,02794927 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 1,255E-03 0,02769286 ! response to gamma radiation GO:0010332 28 14 1,000 1,255E-03 0,0274411 ! skeletal muscle fiber development GO:0048741 111 56 2,000 1,265E-03 0,02742342 ! regulation of DNA replication GO:0006275 101 56 2,000 1,265E-03 0,02717857 ! muscle fiber development GO:0048747 112 57 2,000 1,332E-03 0,02835667 ! lipid modification GO:0030258 97 57 2,000 1,332E-03 0,02810793 ! regulation of intracellular transport GO:0032386 101 57 2,000 1,332E-03 0,02786351 ! superoxide anion generation GO:0042554 20 15 1,000 1,444E-03 0,02995089 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,444E-03 0,0296949 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,444E-03 0,02944325 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 1,444E-03 0,02919583 ! regulation of ATPase activity GO:0043462 21 15 1,000 1,444E-03 0,02895253 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 1,472E-03 0,02926135 ! establishment of organelle localization GO:0051656 109 59 2,000 1,472E-03 0,0290215 ! regulation of protein complex assembly GO:0043254 117 61 2,000 1,62E-03 0,03169351 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 1,62E-03 0,03143792 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,646E-03 0,0316866 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 1,646E-03 0,03143512 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 1,646E-03 0,0311876 GO:0031114|regulation of microtubule depolymerization, ! intermediate filament-based process GO:0045103 32 16 1,000 1,646E-03 0,03094394 ! axon cargo transport GO:0008088 43 16 1,000 1,646E-03 0,03070407 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,646E-03 0,03046788 ! viral reproductive process GO:0022415 126 62 2,000 1,698E-03 0,03118551 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 1,778E-03 0,03240775 ! regulation of survival gene product expression GO:0045884 33 17 1,000 1,861E-03 0,03366804 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 1,861E-03 0,03341679 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 1,861E-03 0,03316926 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,861E-03 0,03292537 ! myeloid cell differentiation GO:0030099 111 65 2,000 1,945E-03 0,03415805 ! cell projection assembly GO:0030031 120 66 2,000 2,032E-03 0,0354281 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,089E-03 0,03615212 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 2,089E-03 0,03589389 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 2,089E-03 0,03563932 ! negative regulation of cell growth GO:0030308 132 67 2,000 2,121E-03 0,03594541 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 2,213E-03 0,03723931 ! viral reproduction GO:0016032 134 68 2,000 2,213E-03 0,0369807 ! negative regulation of cell size GO:0045792 134 69 2,000 2,308E-03 0,03828999 ! lipid phosphorylation GO:0046834 35 19 1,000 2,329E-03 0,03837313 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,581E-03 0,04224228 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 2,581E-03 0,04195686 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 2,581E-03 0,04167527 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 2,581E-03 0,04139744 ! cellular response to starvation GO:0009267 33 20 1,000 2,581E-03 0,04112328 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 2,581E-03 0,04085274 ! peptidyl-serine modification GO:0018209 43 20 1,000 2,581E-03 0,04058572 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 2,581E-03 0,04032218 ! organelle localization GO:0051640 136 74 2,000 2,816E-03 0,04371507 ! axis specification GO:0009798 38 21 1,000 2,846E-03 0,04388674 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 2,846E-03 0,0436072 ! cell aging GO:0007569 44 21 1,000 2,846E-03 0,04333121 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 2,846E-03 0,04305869 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 3,122E-03 0,04695246 ! apoptotic nuclear changes GO:0030262 32 22 1,000 3,122E-03 0,04666083 ! microtubule-based transport GO:0010970 54 22 1,000 3,122E-03 0,0463728 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 3,122E-03 0,04608831 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 3,122E-03 0,04580728 ! protein oligomerization GO:0051259 139 78 2,000 3,269E-03 0,04766929 ! positive regulation of DNA replication GO:0045740 43 23 1,000 3,411E-03 0,04944324 ! gluconeogenesis GO:0006094 33 23 1,000 3,411E-03 0,04914717 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 3,411E-03 0,04885463 ! sex determination GO:0007530 47 23 1,000 3,411E-03 0,04856555 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 3,411E-03 0,04827987 ! muscle cell differentiation GO:0042692 159 80 2,000 3,511E-03 0,04940426 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 3,712E-03 0,05192823 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 3,712E-03 0,05162806 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 3,712E-03 0,05133135 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 3,764E-03 0,05175182 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 4,025E-03 0,05502501 ! vasculogenesis GO:0001570 46 25 1,000 4,025E-03 0,05471414 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 4,025E-03 0,05440676 ! negative regulation of DNA replication GO:0008156 42 25 1,000 4,025E-03 0,05410281 ! response to starvation GO:0042594 42 25 1,000 4,025E-03 0,05380224 ! negative regulation of cell development GO:0010721 73 25 1,000 4,025E-03 0,05350499 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 4,025E-03 0,053211 ! cellular response to nutrient levels GO:0031669 41 25 1,000 4,025E-03 0,05292023 ! negative regulation of growth GO:0045926 155 84 2,000 4,028E-03 0,052669 ! mitochondrion organization GO:0007005 148 86 2,000 4,303E-03 0,05595697 ! embryonic pattern specification GO:0009880 44 26 1,000 4,35E-03 0,05626665 ! initiation of viral infection GO:0019059 57 26 1,000 4,35E-03 0,05596575 ! pyruvate metabolic process GO:0006090 38 26 1,000 4,35E-03 0,05566806 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 4,35E-03 0,05537352 ! blastocyst development GO:0001824 49 26 1,000 4,35E-03 0,05508208 ! regulation of protein transport GO:0051223 154 87 2,000 4,444E-03 0,05598177 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 2,000 4,588E-03 0,05749854 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 4,686E-03 0,05841976 ! protein amino acid acylation GO:0043543 55 27 1,000 4,686E-03 0,05811863 ! superoxide metabolic process GO:0006801 38 27 1,000 4,686E-03 0,05782058 ! mitochondrial membrane organization GO:0007006 57 27 1,000 4,686E-03 0,05752558 ! base-excision repair GO:0006284 41 27 1,000 4,686E-03 0,05723357 ! regulation of chromosome organization GO:0033044 42 27 1,000 4,686E-03 0,05694451 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 4,736E-03 0,05725469 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 5,034E-03 0,06056217 ! regulation of pH GO:0006885 43 29 1,000 5,394E-03 0,06456536 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 5,394E-03 0,06424572 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 5,394E-03 0,06392924 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 1,000 5,765E-03 0,06799218 ! regulation of protein localization GO:0032880 176 97 2,000 6,015E-03 0,07060061 ! iron ion homeostasis GO:0055072 54 31 1,000 6,147E-03 0,07179863 ! response to ionizing radiation GO:0010212 65 32 1,000 6,541E-03 0,07602785 ! response to mechanical stimulus GO:0009612 57 32 1,000 6,541E-03 0,07566233 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 6,541E-03 0,07530031 ! hexose biosynthetic process GO:0019319 48 32 1,000 6,541E-03 0,07494173 ! positive regulation of catabolic process GO:0009896 64 32 1,000 6,541E-03 0,07458656 ! DNA damage checkpoint GO:0000077 71 33 1,000 6,946E-03 0,07882984 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 6,946E-03 0,07845975 ! negative regulation of protein transport GO:0051224 69 33 1,000 6,946E-03 0,07809311 ! placenta development GO:0001890 53 34 1,000 7,362E-03 0,08238507 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 7,789E-03 0,08675993 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 7,789E-03 0,08636011 ! DNA integrity checkpoint GO:0031570 75 36 1,000 8,227E-03 0,09079715 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 8,227E-03 0,09038255 ! tissue remodeling GO:0048771 76 37 1,000 8,676E-03 0,09487945 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 8,676E-03 0,09445013 ! glycogen metabolic process GO:0005977 61 37 1,000 8,676E-03 0,09402468 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 9,135E-03 0,09856072 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 9,135E-03 0,09812072 ! carbohydrate homeostasis GO:0033500 53 38 1,000 9,135E-03 0,09768463 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 1,000 9,135E-03 0,0972524 ! glucan metabolic process GO:0044042 62 38 1,000 9,135E-03 0,09682397 GO:0006073|cellular glucan metabolic process, ! ear morphogenesis GO:0042471 60 39 1,000 9,605E-03 0,10136077 ! segmentation GO:0035282 67 39 1,000 9,605E-03 0,10091815 ! T cell differentiation GO:0030217 81 41 1,000 0,01057723 0,11064702 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01107887 0,11539286 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01107887 0,11489548 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,01107887 0,11440237 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,01107887 0,11391347 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01159082 0,1186703 ! double-strand break repair GO:0006302 81 44 1,000 0,01211302 0,12349119 ! B cell differentiation GO:0030183 107 44 1,000 0,01211302 0,12297013 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01264537 0,1278351 ! pigmentation GO:0043473 100 46 1,000 0,01318779 0,13276073 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01318779 0,13220756 ! mitochondrial transport GO:0006839 82 48 1,000 0,01430251 0,14278772 ! cellular component disassembly GO:0022411 86 48 1,000 0,01430251 0,14219769 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,01487465 0,14727741 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,01487465 0,14667381 ! histone modification GO:0016570 91 50 1,000 0,01545654 0,15178949 ! viral infectious cycle GO:0019058 99 51 1,000 0,01604808 0,15695808 ! positive regulation of growth GO:0045927 90 52 1,000 0,01664921 0,16217818 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01664921 0,16152423 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01725985 0,16677589 ! response to UV GO:0009411 104 53 1,000 0,01725985 0,16610879 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,01787991 0,17139067 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01850931 0,17671987 ! aging GO:0007568 103 55 1,000 0,01850931 0,17602137 ! heart morphogenesis GO:0003007 97 55 1,000 0,01850931 0,17532837 ! nuclear export GO:0051168 97 55 1,000 0,01850931 0,17464081 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01878469 0,17654671 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01878469 0,17585975 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01878469 0,17517813 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01878469 0,17450176 ! neuron fate determination GO:0048664 7 5 0,000 0,01878469 0,1738306 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01878469 0,17316459 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01878469 0,17250365 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01878469 0,17184774 ! polyol transport GO:0015791 12 5 0,000 0,01878469 0,17119681 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01878469 0,17055078 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01878469 0,16990961 ! response to superoxide GO:0000303 10 5 0,000 0,01878469 0,16927325 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01878469 0,16864163 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01878469 0,16801471 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01878469 0,16739243 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01878469 0,16677475 ! female meiosis GO:0007143 7 5 0,000 0,01878469 0,16616161 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01878469 0,16555296 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01878469 0,16494875 ! cobalt ion transport GO:0006824 11 5 0,000 0,01878469 0,16434893 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01878469 0,16375347 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01878469 0,1631623 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01878469 0,16257538 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01878469 0,16199268 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01878469 0,16141413 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01878469 0,1608397 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01878469 0,16026935 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01878469 0,15970303 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01878469 0,15914069 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01878469 0,15858231 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01878469 0,15802782 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01878469 0,1574772 ! negative chemotaxis GO:0050919 14 5 0,000 0,01878469 0,15693041 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01878469 0,15638739 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01878469 0,15584813 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01878469 0,15531257 ! behavioral response to pain GO:0048266 9 5 0,000 0,01878469 0,15478067 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01878469 0,15425241 ! Notch receptor processing GO:0007220 8 5 0,000 0,01878469 0,15372774 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01878469 0,15320663 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01878469 0,15268904 ! micturition GO:0060073 9 5 0,000 0,01878469 0,15217494 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01878469 0,15166428 ! copulation GO:0007620 9 5 0,000 0,01878469 0,15115705 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01878469 0,15065319 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01878469 0,15015268 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01878469 0,14965549 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01878469 0,14916157 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01878469 0,14867091 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01878469 0,14818347 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01878469 0,14769921 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01878469 0,1472181 ! grooming behavior GO:0007625 6 5 0,000 0,01878469 0,14674012 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01878469 0,14626523 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01878469 0,14579341 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01878469 0,14532462 ! response to protozoan GO:0001562 10 5 0,000 0,01878469 0,14485884 ! lymph vessel development GO:0001945 10 5 0,000 0,01878469 0,14439603 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01878469 0,14393617 ! endochondral ossification GO:0001958 16 5 0,000 0,01878469 0,14347923 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01878469 0,14302518 ! parathyroid gland development GO:0060017 13 5 0,000 0,01878469 0,142574 ! anagen GO:0042640 6 5 0,000 0,01878469 0,14212565 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01878469 0,14168012 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01878469 0,14123737 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01878469 0,14079737 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01878469 0,14036011 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01878469 0,13992556 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01878469 0,13949369 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01878469 0,13906448 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01878469 0,1386379 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01878469 0,13821394 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01878469 0,13779255 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01878469 0,13737373 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01878469 0,13695745 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01878469 0,13654368 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01878469 0,1361324 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01878469 0,13572359 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01878469 0,13531724 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01878469 0,1349133 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01878469 0,13451178 ! histidine catabolic process GO:0006548 6 5 0,000 0,01878469 0,13411263 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01878469 0,13371585 ! microvillus organization GO:0032528 7 5 0,000 0,01878469 0,13332141 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01878469 0,13292929 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01878469 0,13253946 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01878469 0,13215192 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01878469 0,13176664 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01878469 0,1313836 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01878469 0,13100277 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01878469 0,13062415 ! polyol catabolic process GO:0046174 7 5 0,000 0,01878469 0,13024771 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01878469 0,12987344 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01878469 0,12950131 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01878469 0,12913131 ! muscle cell migration GO:0014812 8 5 0,000 0,01878469 0,12876341 ! mitochondrial fission GO:0000266 8 5 0,000 0,01878469 0,1283976 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01878469 0,12803387 ! mRNA transcription GO:0009299 9 5 0,000 0,01878469 0,12767219 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01878469 0,12731255 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01878469 0,12695494 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01878469 0,12659932 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01878469 0,12624569 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01878469 0,12589403 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01878469 0,12554432 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01878469 0,12519656 ! response to food GO:0032094 6 5 0,000 0,01878469 0,12485071 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01878469 0,12450677 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01878469 0,12416472 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01878469 0,12382454 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01878469 0,12348622 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01878469 0,12314975 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01878469 0,1228151 ! forebrain neuron development GO:0021884 13 5 0,000 0,01878469 0,12248227 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01878469 0,12215123 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01878469 0,12182199 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01878469 0,12149451 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01878469 0,12116879 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01878469 0,1208448 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01878469 0,12052255 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01878469 0,12020201 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01878469 0,11988317 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01878469 0,11956602 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01878469 0,11925055 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01878469 0,11893673 ! basic amino acid transport GO:0015802 11 5 0,000 0,01878469 0,11862456 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01878469 0,11831402 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01878469 0,11800511 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01878469 0,1176978 ! depyrimidination GO:0045008 10 5 0,000 0,01878469 0,1173921 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01878469 0,11708797 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01878469 0,11678542 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01878469 0,11648443 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01878469 0,11618498 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01878469 0,11588707 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01878469 0,11559068 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01878469 0,11529581 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01878469 0,11500243 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01878469 0,11471055 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01878469 0,11442014 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01878469 0,1141312 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01878469 0,11384372 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01878469 0,11355768 ! response to arsenic GO:0046685 10 5 0,000 0,01878469 0,11327308 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01878469 0,11298989 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01878469 0,11270812 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01878469 0,11242775 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01878469 0,11214878 ! response to cadmium ion GO:0046686 7 5 0,000 0,01878469 0,11187118 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01878469 0,11159496 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01878469 0,11132009 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01878469 0,11104658 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01878469 0,1107744 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01878469 0,11050356 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01878469 0,11023404 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01878469 0,10996583 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01878469 0,10969892 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01878469 0,10943331 ! neural tube patterning GO:0021532 7 5 0,000 0,01878469 0,10916898 ! embryonic cleavage GO:0040016 6 5 0,000 0,01878469 0,10890592 ! peroxisome fission GO:0016559 5 5 0,000 0,01878469 0,10864413 ! histone demethylation GO:0016577 10 5 0,000 0,01878469 0,10838359 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01878469 0,1081243 ! mitotic recombination GO:0006312 9 5 0,000 0,01878469 0,10786625 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01878469 0,10760942 ! metaphase plate congression GO:0051310 7 5 0,000 0,01878469 0,10735382 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01878469 0,10709942 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01878469 0,10684623 ! enteric nervous system development GO:0048484 8 5 0,000 0,01878469 0,10659424 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01878469 0,10634343 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01878469 0,1060938 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01878469 0,10584533 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01878469 0,10559803 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01878469 0,10535188 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01878469 0,10510688 ! plasminogen activation GO:0031639 5 5 0,000 0,01878469 0,10486301 ! B cell homeostasis GO:0001782 13 5 0,000 0,01878469 0,10462027 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01878469 0,10437865 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01878469 0,10413815 ! metaphase GO:0051323 8 5 0,000 0,01878469 0,10389875 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01878469 0,10366045 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01878469 0,10342324 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01878469 0,10318712 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01878469 0,10295207 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01878469 0,10271808 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01878469 0,10248516 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01878469 0,1022533 ! response to redox state GO:0051775 5 5 0,000 0,01878469 0,10202248 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01878469 0,1017927 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01878469 0,10156395 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01878469 0,10133623 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01878469 0,10110952 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01878469 0,10088383 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01878469 0,10065915 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01878469 0,10043546 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01878469 0,10021276 ! striatum development GO:0021756 9 5 0,000 0,01878469 0,09999106 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01878469 0,09977032 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01878469 0,09955057 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01878469 0,09933177 ! glial cell migration GO:0008347 11 5 0,000 0,01878469 0,09911394 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01878469 0,09889706 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01878469 0,09868113 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01878469 0,09846614 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01878469 0,09825208 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01878469 0,09803895 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01878469 0,09782675 ! neuroprotection GO:0043526 6 5 0,000 0,01878469 0,09761546 ! neural plate development GO:0001840 8 5 0,000 0,01878469 0,09740508 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01878469 0,09719561 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01878469 0,09698703 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01878469 0,09677935 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01878469 0,09657256 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01878469 0,09636665 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01878469 0,09616161 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01878469 0,09595745 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01878469 0,09575415 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01878469 0,09555171 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01878469 0,09535012 ! spindle assembly GO:0051225 6 5 0,000 0,01878469 0,09514938 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01878469 0,09494949 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01878469 0,09475043 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01878469 0,09455221 ! drug metabolic process GO:0017144 6 5 0,000 0,01878469 0,09435482 ! stem cell division GO:0017145 11 5 0,000 0,01878469 0,09415824 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01878469 0,09396249 ! organ regeneration GO:0031100 7 5 0,000 0,01878469 0,09376755 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01878469 0,09357341 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01878469 0,09338008 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01878469 0,09318754 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01914798 0,09479434 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,01979585 0,09780042 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,01979585 0,09760001 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,02111883 0,10390982 ! DNA catabolic process GO:0006308 86 59 1,000 0,02111883 0,10369775 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,02179379 0,10679403 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,02179379 0,10657697 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02249944 0,10980455 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02249944 0,10958228 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02249944 0,1093609 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02249944 0,10914041 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02249944 0,10892081 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02249944 0,1087021 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02249944 0,10848426 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02249944 0,10826729 ! sleep GO:0030431 13 6 0,000 0,02249944 0,10805119 ! response to oxygen radical GO:0000305 11 6 0,000 0,02249944 0,10783595 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02249944 0,10762156 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02249944 0,10740803 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02249944 0,10719534 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02249944 0,10698349 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02249944 0,10677248 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02249944 0,10656229 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02249944 0,10635294 ! forebrain regionalization GO:0021871 8 6 0,000 0,02249944 0,1061444 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02249944 0,10593668 ! male meiosis GO:0007140 7 6 0,000 0,02249944 0,10572978 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02249944 0,10552367 ! response to zinc ion GO:0010043 9 6 0,000 0,02249944 0,10531838 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02249944 0,10511387 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02249944 0,10491016 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02249944 0,10470724 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02249944 0,10450511 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02249944 0,10430375 ! malate metabolic process GO:0006108 11 6 0,000 0,02249944 0,10410316 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02249944 0,10390335 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02249944 0,1037043 ! protein refolding GO:0042026 15 6 0,000 0,02249944 0,10350601 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02249944 0,10330848 ! opsonization GO:0008228 8 6 0,000 0,02249944 0,1031117 ! mating behavior GO:0007617 7 6 0,000 0,02249944 0,10291567 ! neuron remodeling GO:0016322 15 6 0,000 0,02249944 0,10272039 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02249944 0,10252584 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02249944 0,10233203 ! equilibrioception GO:0050957 14 6 0,000 0,02249944 0,10213895 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02249944 0,1019466 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02249944 0,10175497 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02249944 0,10156406 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02249944 0,10137387 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02249944 0,10118438 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02249944 0,10099561 ! toxin metabolic process GO:0009404 11 6 0,000 0,02249944 0,10080753 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02249944 0,10062016 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02249944 0,10043348 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02249944 0,10024749 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02249944 0,10006219 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02249944 0,09987757 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02249944 0,09969364 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02249944 0,09951038 ! thymic T cell selection GO:0045061 12 6 0,000 0,02249944 0,09932779 ! protein lipoylation GO:0009249 10 6 0,000 0,02249944 0,09914587 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02249944 0,09896462 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02249944 0,09878402 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02249944 0,09860409 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02249944 0,09842481 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02249944 0,09824618 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02249944 0,0980682 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02249944 0,09789086 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02249944 0,09771416 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02249944 0,0975381 ! hyperosmotic response GO:0006972 9 6 0,000 0,02249944 0,09736267 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02249944 0,09718787 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02249944 0,0970137 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02249944 0,09684015 ! urea metabolic process GO:0019627 7 6 0,000 0,02249944 0,09666722 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02249944 0,09649491 ! neutrophil activation GO:0042119 8 6 0,000 0,02249944 0,09632321 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02249944 0,09615212 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02249944 0,09598164 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02249944 0,09581176 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02249944 0,09564248 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02249944 0,0954738 ! neuron apoptosis GO:0051402 9 6 0,000 0,02249944 0,09530571 ! nucleoside salvage GO:0043174 9 6 0,000 0,02249944 0,09513822 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02249944 0,09497131 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02249944 0,09480498 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02249944 0,09463924 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02249944 0,09447407 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02249944 0,09430949 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02249944 0,09414547 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02249944 0,09398202 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02249944 0,09381914 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02249944 0,09365683 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02249944 0,09349507 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02249944 0,09333387 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02249944 0,09317323 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02249944 0,09301314 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02249944 0,09285359 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02249944 0,0926946 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02249944 0,09253615 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02249944 0,09237823 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02249944 0,09222086 ! neural nucleus development GO:0048857 14 6 0,000 0,02249944 0,09206402 ! response to UV-C GO:0010225 11 6 0,000 0,02249944 0,09190772 ! astrocyte development GO:0014002 15 6 0,000 0,02249944 0,09175194 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02249944 0,09159669 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02249944 0,09144197 ! interaction with symbiont GO:0051702 13 6 0,000 0,02249944 0,09128777 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02249944 0,09113408 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02249944 0,09098092 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02249944 0,09082826 ! response to copper ion GO:0046688 10 6 0,000 0,02249944 0,09067612 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02249944 0,09052449 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02249944 0,09037336 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02249944 0,09022274 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02249944 0,09007262 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02249944 0,089923 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02249944 0,08977387 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02249944 0,08962524 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02249944 0,0894771 ! hair follicle maturation GO:0048820 7 6 0,000 0,02249944 0,08932945 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02249944 0,08918228 ! Schwann cell development GO:0014044 15 6 0,000 0,02249944 0,0890356 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02249944 0,0888894 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02249944 0,08874368 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02249944 0,08859844 ! subpallium development GO:0021544 10 6 0,000 0,02249944 0,08845367 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02249944 0,08830937 ! histone ubiquitination GO:0016574 8 6 0,000 0,02249944 0,08816555 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02249944 0,08802219 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02249944 0,08787929 ! G2 phase GO:0051319 16 6 0,000 0,02249944 0,08773686 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02249944 0,08759489 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02249944 0,08745338 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02249944 0,08731233 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02249944 0,08717173 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02249944 0,08703158 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02249944 0,08689189 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02249944 0,08675264 ! receptor internalization GO:0031623 10 6 0,000 0,02249944 0,08661383 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02249944 0,08647547 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02249944 0,08633755 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02249944 0,08620007 ! protein deubiquitination GO:0016579 14 6 0,000 0,02249944 0,08606303 ! protein destabilization GO:0031648 9 6 0,000 0,02249944 0,08592642 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02249944 0,08579025 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02249944 0,0856545 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02249944 0,08551919 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02249944 0,0853843 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02249944 0,08524983 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02249944 0,08511579 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02249944 0,08498217 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02249944 0,08484897 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02249944 0,08471619 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02249944 0,08458382 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02249944 0,08445186 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02249944 0,08432032 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02249944 0,08418918 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02249944 0,08405845 ! catecholamine transport GO:0051937 9 6 0,000 0,02249944 0,08392813 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02249944 0,08379821 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02249944 0,08366869 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02249944 0,08353958 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02249944 0,08341086 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02249944 0,08328253 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02249944 0,0831546 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02249944 0,08302706 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02249944 0,08289992 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02249944 0,08277316 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02249944 0,08264679 ! ear development GO:0043583 103 62 1,000 0,0231703 0,08498131 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,0231703 0,08485197 ! detection of external stimulus GO:0009581 91 63 1,000 0,02387169 0,08728766 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,02458173 0,08974757 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,02458173 0,08961159 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 146 64 1,000 0,02458173 0,08947602 ! tRNA transcription GO:0009304 14 7 0,000 0,02620025 0,09522325 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02620025 0,09507963 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02620025 0,09493643 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02620025 0,09479367 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02620025 0,09465134 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02620025 0,09450943 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02620025 0,09436795 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02620025 0,09422689 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02620025 0,09408626 ! prostate gland development GO:0030850 13 7 0,000 0,02620025 0,09394604 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02620025 0,09380624 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02620025 0,09366685 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02620025 0,09352788 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02620025 0,09338932 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02620025 0,09325117 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02620025 0,09311343 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02620025 0,09297609 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02620025 0,09283916 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02620025 0,09270263 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02620025 0,09256651 ! glycolipid transport GO:0046836 10 7 0,000 0,02620025 0,09243078 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02620025 0,09229545 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02620025 0,09216051 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02620025 0,09202597 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02620025 0,09189182 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02620025 0,09175807 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02620025 0,0916247 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02620025 0,09149172 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02620025 0,09135912 ! mRNA stabilization GO:0048255 18 7 0,000 0,02620025 0,09122691 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02620025 0,09109507 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02620025 0,09096362 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02620025 0,09083255 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02620025 0,09070186 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02620025 0,09057154 ! lipoprotein transport GO:0042953 14 7 0,000 0,02620025 0,0904416 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02620025 0,09031202 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02620025 0,09018282 ! rhythmic behavior GO:0007622 15 7 0,000 0,02620025 0,09005399 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02620025 0,08992552 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02620025 0,08979742 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02620025 0,08966969 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02620025 0,08954232 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02620025 0,08941531 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02620025 0,08928866 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02620025 0,08916236 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02620025 0,08903643 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02620025 0,08891085 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02620025 0,08878562 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02620025 0,08866075 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02620025 0,08853622 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02620025 0,08841205 ! spinal cord patterning GO:0021511 13 7 0,000 0,02620025 0,08828822 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02620025 0,08816474 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02620025 0,08804161 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02620025 0,08791882 ! adrenal gland development GO:0030325 17 7 0,000 0,02620025 0,08779637 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02620025 0,08767426 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02620025 0,08755249 ! ovulation GO:0030728 9 7 0,000 0,02620025 0,08743106 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02620025 0,08730996 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02620025 0,0871892 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02620025 0,08706877 ! microtubule nucleation GO:0007020 20 7 0,000 0,02620025 0,08694868 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02620025 0,08682891 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02620025 0,08670948 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02620025 0,08659037 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02620025 0,08647159 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02620025 0,08635314 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02620025 0,08623501 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02620025 0,0861172 ! galactose metabolic process GO:0006012 13 7 0,000 0,02620025 0,08599972 ! vesicle fusion GO:0006906 17 7 0,000 0,02620025 0,08588255 ! response to dietary excess GO:0002021 8 7 0,000 0,02620025 0,0857657 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02620025 0,08564917 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02620025 0,08553296 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02620025 0,08541706 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02620025 0,08530148 ! organ growth GO:0035265 15 7 0,000 0,02620025 0,08518621 ! purine salvage GO:0043101 10 7 0,000 0,02620025 0,08507124 ! nucleoside transport GO:0015858 8 7 0,000 0,02620025 0,08495659 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02620025 0,08484225 ! parturition GO:0007567 14 7 0,000 0,02620025 0,08472821 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02620025 0,08461449 ! rRNA modification GO:0000154 14 7 0,000 0,02620025 0,08450106 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02620025 0,08438794 ! spindle checkpoint GO:0031577 15 7 0,000 0,02620025 0,08427512 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02620025 0,08416261 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02620025 0,08405039 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02620025 0,08393847 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02620025 0,08382685 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02620025 0,08371553 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02620025 0,0836045 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02620025 0,08349376 ! fibrinolysis GO:0042730 10 7 0,000 0,02620025 0,08338332 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02620025 0,08327317 ! eating behavior GO:0042755 7 7 0,000 0,02620025 0,08316331 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02620025 0,08305374 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02620025 0,08294446 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02620025 0,08283547 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02620025 0,08272676 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02620025 0,08261834 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02620025 0,0825102 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02620025 0,08240234 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02620025 0,08229477 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02620025 0,08218747 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02620025 0,08208046 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02620025 0,08197372 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02620025 0,08186726 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02620025 0,08176108 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02620025 0,08165517 ! regulation of meiosis GO:0040020 12 7 0,000 0,02620025 0,08154954 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02620025 0,08144418 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02620025 0,08133909 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02620025 0,08123427 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02620025 0,08112972 ! transcription termination GO:0006353 13 7 0,000 0,02620025 0,08102544 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02620025 0,08092143 ! anaphase GO:0051322 17 7 0,000 0,02620025 0,08081768 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02620025 0,0807142 ! axonal fasciculation GO:0007413 18 7 0,000 0,02620025 0,08061099 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02620025 0,08050804 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02620025 0,08040535 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02620025 0,08030292 ! diuresis GO:0030146 12 7 0,000 0,02620025 0,08020075 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02620025 0,08009885 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02620025 0,0799972 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02620025 0,07989581 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02620025 0,07979467 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02620025 0,07969379 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02620025 0,07959317 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02620025 0,0794928 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02620025 0,07939268 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02620025 0,07929282 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02620025 0,07919321 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02620025 0,07909384 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02620025 0,07899473 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02620025 0,07889586 ! lymph node development GO:0048535 10 7 0,000 0,02620025 0,07879724 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02620025 0,07869887 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02620025 0,07860074 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02620025 0,07850285 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02620025 0,07840521 ! adult feeding behavior GO:0008343 9 7 0,000 0,02620025 0,07830782 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02620025 0,07821066 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02620025 0,07811374 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02620025 0,07801707 ! muscle adaptation GO:0043500 14 7 0,000 0,02620025 0,07792063 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02620025 0,07782443 ! retina homeostasis GO:0001895 12 7 0,000 0,02620025 0,07772847 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02620025 0,07763275 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02620025 0,07753726 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02620025 0,077442 ! protein prenylation GO:0018342 18 7 0,000 0,02620025 0,07734698 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02620025 0,0772522 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02620025 0,07715764 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02620025 0,07706332 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,02676306 0,07862263 ! activation of MAPK activity GO:0000187 115 67 1,000 0,02676306 0,07852674 ! lung development GO:0030324 144 67 1,000 0,02676306 0,0784311 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,027507 0,08051318 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,02825922 0,08261443 ! respiratory tube development GO:0030323 150 70 1,000 0,02901965 0,08473457 ! B cell activation GO:0042113 160 71 1,000 0,02978824 0,08687334 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02988717 0,08705632 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02988717 0,08695105 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,02988717 0,08684604 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02988717 0,08674128 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02988717 0,08663677 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02988717 0,08653252 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02988717 0,08642851 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02988717 0,08632476 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02988717 0,08622125 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02988717 0,08611799 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02988717 0,08601498 ! meiotic prophase I GO:0007128 13 8 0,000 0,02988717 0,08591221 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02988717 0,08580969 ! oligopeptide transport GO:0006857 15 8 0,000 0,02988717 0,08570742 ! UTP metabolic process GO:0046051 8 8 0,000 0,02988717 0,08560538 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02988717 0,08550359 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02988717 0,08540205 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02988717 0,08530074 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02988717 0,08519967 ! succinate metabolic process GO:0006105 14 8 0,000 0,02988717 0,08509884 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02988717 0,08499825 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02988717 0,0848979 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02988717 0,08479779 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02988717 0,08469791 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02988717 0,08459826 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02988717 0,08449885 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02988717 0,08439967 ! reflex GO:0060004 16 8 0,000 0,02988717 0,08430073 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02988717 0,08420202 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02988717 0,08410353 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02988717 0,08400528 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02988717 0,08390726 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02988717 0,08380947 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02988717 0,0837119 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02988717 0,08361456 ! pigment granule organization GO:0048753 16 8 0,000 0,02988717 0,08351745 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02988717 0,08342056 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02988717 0,0833239 ! histidine metabolic process GO:0006547 16 8 0,000 0,02988717 0,08322746 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02988717 0,08313124 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02988717 0,08303524 ! glycine catabolic process GO:0006546 13 8 0,000 0,02988717 0,08293947 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02988717 0,08284392 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02988717 0,08274859 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02988717 0,08265347 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02988717 0,08255858 ! melanin metabolic process GO:0006582 15 8 0,000 0,02988717 0,0824639 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02988717 0,08236944 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02988717 0,0822752 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02988717 0,08218117 ! macrophage activation GO:0042116 12 8 0,000 0,02988717 0,08208735 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02988717 0,08199375 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02988717 0,08190037 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02988717 0,08180719 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02988717 0,08171423 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02988717 0,08162148 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02988717 0,08152894 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02988717 0,0814366 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02988717 0,08134448 ! osteoblast development GO:0002076 16 8 0,000 0,02988717 0,08125257 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02988717 0,08116086 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02988717 0,08106936 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02988717 0,08097807 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02988717 0,08088698 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02988717 0,08079609 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02988717 0,08070541 ! response to UV-B GO:0010224 16 8 0,000 0,02988717 0,08061494 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02988717 0,08052466 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02988717 0,08043459 ! intermediate filament organization GO:0045109 12 8 0,000 0,02988717 0,08034472 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02988717 0,08025505 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02988717 0,08016558 ! cellular extravasation GO:0045123 12 8 0,000 0,02988717 0,08007631 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02988717 0,07998723 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02988717 0,07989836 ! response to antibiotic GO:0046677 11 8 0,000 0,02988717 0,07980968 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02988717 0,0797212 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02988717 0,07963291 ! DNA topological change GO:0006265 12 8 0,000 0,02988717 0,07954483 ! response to tropane GO:0014073 15 8 0,000 0,02988717 0,07945693 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02988717 0,07936923 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02988717 0,07928172 ! melanosome transport GO:0032402 13 8 0,000 0,02988717 0,07919441 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02988717 0,07910729 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02988717 0,07902035 ! mast cell activation GO:0045576 14 8 0,000 0,02988717 0,07893361 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02988717 0,07884706 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02988717 0,0787607 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02988717 0,07867453 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02988717 0,07858855 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02988717 0,07850275 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02988717 0,07841715 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02988717 0,07833172 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02988717 0,07824649 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02988717 0,07816144 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02988717 0,07807657 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02988717 0,07799189 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02988717 0,07790739 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02988717 0,07782308 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02988717 0,07773894 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02988717 0,07765499 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02988717 0,07757122 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02988717 0,07748763 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02988717 0,07740422 ! hormone catabolic process GO:0042447 17 8 0,000 0,02988717 0,07732099 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02988717 0,07723794 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02988717 0,07715507 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02988717 0,07707237 ! ATP catabolic process GO:0006200 11 8 0,000 0,02988717 0,07698985 ! blastocyst growth GO:0001832 19 8 0,000 0,02988717 0,07690751 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02988717 0,07682534 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02988717 0,07674335 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02988717 0,07666154 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02988717 0,0765799 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02988717 0,07649843 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02988717 0,07641713 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02988717 0,07633601 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02988717 0,07625506 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02988717 0,07617428 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02988717 0,07609367 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02988717 0,07601324 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02988717 0,07593297 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02988717 0,07585287 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02988717 0,07577294 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02988717 0,07569318 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02988717 0,07561359 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0305649 0,07724699 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,0305649 0,07716594 ! respiratory system development GO:0060541 153 72 1,000 0,0305649 0,07708505 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,03214215 0,08097802 GO:0090046|regulation of transcription regulator activity, ! cell-matrix adhesion GO:0007160 163 75 1,000 0,0329426 0,08290785 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,0329426 0,08282122 ! axon extension GO:0048675 15 9 0,000 0,03356025 0,08428597 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03356025 0,08419808 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03356025 0,08411038 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03356025 0,08402285 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03356025 0,08393551 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03356025 0,08384835 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03356025 0,08376137 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03356025 0,08367457 ! phosphate transport GO:0006817 19 9 0,000 0,03356025 0,08358795 ! reproductive behavior GO:0019098 19 9 0,000 0,03356025 0,08350151 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03356025 0,08341525 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03356025 0,08332916 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03356025 0,08324326 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03356025 0,08315753 ! GTP metabolic process GO:0046039 9 9 0,000 0,03356025 0,08307198 ! RNA methylation GO:0001510 15 9 0,000 0,03356025 0,0829866 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03356025 0,0829014 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03356025 0,08281637 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03356025 0,08273152 ! artery development GO:0060840 24 9 0,000 0,03356025 0,08264684 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03356025 0,08256233 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03356025 0,082478 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03356025 0,08239384 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03356025 0,08230985 ! chemosensory behavior GO:0007635 20 9 0,000 0,03356025 0,08222603 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03356025 0,08214238 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03356025 0,0820589 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03356025 0,08197559 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03356025 0,08189245 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03356025 0,08180948 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03356025 0,08172668 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03356025 0,08164404 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03356025 0,08156158 ! protein targeting to ER GO:0045047 22 9 0,000 0,03356025 0,08147927 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03356025 0,08139714 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03356025 0,08131517 ! T cell selection GO:0045058 23 9 0,000 0,03356025 0,08123336 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03356025 0,08115172 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03356025 0,08107024 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03356025 0,08098893 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03356025 0,08090778 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03356025 0,08082679 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03356025 0,08074596 ! mannose metabolic process GO:0006013 13 9 0,000 0,03356025 0,0806653 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03356025 0,08058479 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03356025 0,08050445 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03356025 0,08042426 ! receptor clustering GO:0043113 18 9 0,000 0,03356025 0,08034424 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03356025 0,08026437 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03356025 0,08018467 ! ruffle organization GO:0031529 15 9 0,000 0,03356025 0,08010512 ! retinol metabolic process GO:0042572 18 9 0,000 0,03356025 0,08002573 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03356025 0,0799465 ! behavioral fear response GO:0001662 22 9 0,000 0,03356025 0,07986742 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03356025 0,0797885 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03356025 0,07970973 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03356025 0,07963112 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03356025 0,07955267 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03356025 0,07947437 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03356025 0,07939622 ! segment specification GO:0007379 13 9 0,000 0,03356025 0,07931823 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03356025 0,07924039 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03356025 0,07916271 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03356025 0,07908517 ! response to amine stimulus GO:0014075 13 9 0,000 0,03356025 0,07900779 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03356025 0,07893056 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03356025 0,07885348 ! erythrocyte development GO:0048821 15 9 0,000 0,03356025 0,07877655 ! gas homeostasis GO:0033483 16 9 0,000 0,03356025 0,07869977 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03356025 0,07862314 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03356025 0,07854665 ! renal water homeostasis GO:0003091 14 9 0,000 0,03356025 0,07847032 ! postreplication repair GO:0006301 22 9 0,000 0,03356025 0,07839414 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03356025 0,0783181 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03356025 0,07824221 ! icosanoid secretion GO:0032309 15 9 0,000 0,03356025 0,07816647 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03356025 0,07809087 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03356025 0,07801542 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03356025 0,07794012 ! regulation of cell division GO:0051302 15 9 0,000 0,03356025 0,07786496 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03356025 0,07778994 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03356025 0,07771507 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03356025 0,07764035 ! sterol catabolic process GO:0016127 11 9 0,000 0,03356025 0,07756576 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03356025 0,07749132 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03356025 0,07741703 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03356025 0,07734287 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03356025 0,07726886 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03356025 0,07719499 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03356025 0,07712126 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03356025 0,07704767 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03356025 0,07697422 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03356025 0,07690091 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03356025 0,07682775 ! purine base metabolic process GO:0006144 21 9 0,000 0,03356025 0,07675472 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03356025 0,07668182 ! pigment granule transport GO:0051904 17 9 0,000 0,03356025 0,07660907 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03356025 0,07653646 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03356025 0,07646398 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03356025 0,07639164 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03356025 0,07631943 ! mitochondrion localization GO:0051646 15 9 0,000 0,03356025 0,07624737 ! regulation of catabolic process GO:0009894 161 76 1,000 0,03375085 0,07660806 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,03539045 0,08025392 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,03622166 0,08206149 ! protein import into nucleus GO:0006606 158 80 1,000 0,03706038 0,08388267 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03721955 0,08416375 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03721955 0,08408472 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03721955 0,08400584 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03721955 0,08392711 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03721955 0,08384853 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03721955 0,08377009 ! synapsis GO:0007129 13 10 0,000 0,03721955 0,0836918 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03721955 0,08361366 ! N-glycan processing GO:0006491 20 10 0,000 0,03721955 0,08353566 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03721955 0,08345781 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03721955 0,0833801 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03721955 0,08330254 ! social behavior GO:0035176 24 10 0,000 0,03721955 0,08322512 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03721955 0,08314785 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03721955 0,08307071 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03721955 0,08299373 ! androgen metabolic process GO:0008209 17 10 0,000 0,03721955 0,08291688 ! phospholipid efflux GO:0033700 16 10 0,000 0,03721955 0,08284018 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03721955 0,08276361 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03721955 0,08268719 ! lung alveolus development GO:0048286 26 10 0,000 0,03721955 0,08261091 ! pathogenesis GO:0009405 13 10 0,000 0,03721955 0,08253477 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03721955 0,08245878 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03721955 0,08238292 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03721955 0,0823072 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03721955 0,08223162 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03721955 0,08215617 ! endoderm development GO:0007492 16 10 0,000 0,03721955 0,08208087 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03721955 0,08200571 ! arginine catabolic process GO:0006527 13 10 0,000 0,03721955 0,08193068 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03721955 0,08185579 ! proline metabolic process GO:0006560 13 10 0,000 0,03721955 0,08178103 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03721955 0,08170641 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03721955 0,08163193 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03721955 0,08155759 ! V(D)J recombination GO:0033151 28 10 0,000 0,03721955 0,08148338 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03721955 0,0814093 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03721955 0,08133536 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03721955 0,08126155 ! B cell proliferation GO:0042100 18 10 0,000 0,03721955 0,08118788 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03721955 0,08111434 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03721955 0,08104093 ! multicellular organism growth GO:0035264 18 10 0,000 0,03721955 0,08096766 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03721955 0,08089452 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03721955 0,08082151 ! epithelial cell development GO:0002064 20 10 0,000 0,03721955 0,08074863 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03721955 0,08067588 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03721955 0,08060327 ! macroautophagy GO:0016236 17 10 0,000 0,03721955 0,08053078 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03721955 0,08045843 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03721955 0,0803862 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03721955 0,08031411 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03721955 0,08024214 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03721955 0,0801703 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03721955 0,0800986 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03721955 0,08002702 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03721955 0,07995556 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03721955 0,07988424 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03721955 0,07981304 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03721955 0,07974197 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03721955 0,07967102 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03721955 0,0796002 ! response to dsRNA GO:0043331 20 10 0,000 0,03721955 0,07952951 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03721955 0,07945894 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03721955 0,0793885 ! melanosome localization GO:0032400 16 10 0,000 0,03721955 0,07931818 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03721955 0,07924799 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03721955 0,07917792 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03721955 0,07910798 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03721955 0,07903816 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03721955 0,07896846 ! mRNA cleavage GO:0006379 17 10 0,000 0,03721955 0,07889888 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03721955 0,07882943 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03721955 0,0787601 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03721955 0,07869089 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03721955 0,0786218 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03721955 0,07855283 ! salivary gland development GO:0007431 27 10 0,000 0,03721955 0,07848399 ! prophase GO:0051324 15 10 0,000 0,03721955 0,07841526 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03721955 0,07834666 ! apical protein localization GO:0045176 15 10 0,000 0,03721955 0,07827817 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03721955 0,07820981 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03721955 0,07814156 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03721955 0,07807344 ! midbrain development GO:0030901 13 10 0,000 0,03721955 0,07800543 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03721955 0,07793754 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03721955 0,07786977 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03721955 0,07780211 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03721955 0,07773457 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03721955 0,07766716 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03721955 0,07759985 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03721955 0,07753267 ! detection of calcium ion GO:0005513 23 10 0,000 0,03721955 0,0774656 ! oocyte development GO:0048599 17 10 0,000 0,03721955 0,07739864 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03721955 0,07733181 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03721955 0,07726508 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03721955 0,07719847 ! activation of innate immune response GO:0002218 12 10 0,000 0,03721955 0,07713198 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03721955 0,0770656 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03721955 0,07699934 ! response to nicotine GO:0035094 20 10 0,000 0,03721955 0,07693319 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03721955 0,07686715 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03721955 0,07680123 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03721955 0,07673542 ! localization within membrane GO:0051668 20 10 0,000 0,03721955 0,07666972 ! T cell activation GO:0042110 168 81 1,000 0,03790656 0,07801812 ! response to hypoxia GO:0001666 171 81 1,000 0,03790656 0,07795144 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,03790656 0,07788487 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,03790656 0,07781842 ! nuclear import GO:0051170 161 81 1,000 0,03790656 0,07775208 ! response to drug GO:0042493 143 82 1,000 0,03876012 0,07943514 ! response to oxygen levels GO:0070482 176 83 1,000 0,039621 0,08113031 ! negative regulation of transport GO:0051051 153 84 1,000 0,04048912 0,08283744 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04086511 0,08353565 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04086511 0,08346473 ! neuron fate specification GO:0048665 17 11 0,000 0,04086511 0,08339394 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04086511 0,08332327 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04086511 0,08325271 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04086511 0,08318228 ! thyroid gland development GO:0030878 26 11 0,000 0,04086511 0,08311197 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,04086511 0,08304177 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04086511 0,08297169 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04086511 0,08290173 ! response to pain GO:0048265 24 11 0,000 0,04086511 0,08283189 ! T cell proliferation GO:0042098 26 11 0,000 0,04086511 0,08276217 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04086511 0,08269256 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04086511 0,08262307 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04086511 0,0825537 ! bone resorption GO:0045453 16 11 0,000 0,04086511 0,08248444 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04086511 0,0824153 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04086511 0,08234628 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04086511 0,08227737 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04086511 0,08220857 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04086511 0,0821399 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04086511 0,08207133 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04086511 0,08200288 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04086511 0,08193455 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,04086511 0,08186632 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04086511 0,08179822 ! UV protection GO:0009650 19 11 0,000 0,04086511 0,08173022 ! adult heart development GO:0007512 14 11 0,000 0,04086511 0,08166234 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04086511 0,08159457 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04086511 0,08152691 ! temperature homeostasis GO:0001659 17 11 0,000 0,04086511 0,08145937 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04086511 0,08139193 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04086511 0,08132461 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04086511 0,0812574 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04086511 0,0811903 ! regulation of organ growth GO:0046620 13 11 0,000 0,04086511 0,08112331 ! pigment granule localization GO:0051875 20 11 0,000 0,04086511 0,08105643 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04086511 0,08098967 ! vasoconstriction GO:0042310 18 11 0,000 0,04086511 0,08092301 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04086511 0,08085646 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04086511 0,08079002 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04086511 0,08072369 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04086511 0,08065747 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04086511 0,08059136 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04086511 0,08052535 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04086511 0,08045946 ! zymogen activation GO:0031638 15 11 0,000 0,04086511 0,08039367 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04086511 0,08032799 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04086511 0,08026241 ! nucleosome positioning GO:0016584 15 11 0,000 0,04086511 0,08019695 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04086511 0,08013159 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04086511 0,08006633 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04086511 0,08000118 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04086511 0,07993614 ! acid secretion GO:0046717 18 11 0,000 0,04086511 0,07987121 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04086511 0,07980638 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04086511 0,07974165 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04086511 0,07967703 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04086511 0,07961251 ! oocyte differentiation GO:0009994 18 11 0,000 0,04086511 0,0795481 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04086511 0,0794838 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04086511 0,07941959 ! cholesterol efflux GO:0033344 19 11 0,000 0,04086511 0,07935549 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04086511 0,0792915 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04086511 0,0792276 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04086511 0,07916381 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 15 11 0,000 0,04086511 0,07910013 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04086511 0,07903654 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04086511 0,07897306 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04086511 0,07890968 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04086511 0,0788464 ! defense response to fungus GO:0050832 13 11 0,000 0,04086511 0,07878322 ! developmental induction GO:0031128 19 11 0,000 0,04086511 0,07872014 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04086511 0,07865716 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04086511 0,07859429 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04086511 0,07853151 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04086511 0,07846884 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04086511 0,07840626 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04086511 0,07834379 ! protein localization in nucleus GO:0034504 176 87 1,000 0,04313633 0,08263217 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04449699 0,08517085 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04449699 0,08510315 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04449699 0,08503555 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04449699 0,08496806 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,04449699 0,08490068 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04449699 0,08483341 ! cartilage condensation GO:0001502 20 12 0,000 0,04449699 0,08476624 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,04449699 0,08469918 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04449699 0,08463222 ! protein complex disassembly GO:0043241 27 12 0,000 0,04449699 0,08456537 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04449699 0,08449863 ! hippocampus development GO:0021766 26 12 0,000 0,04449699 0,08443199 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,04449699 0,08436545 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04449699 0,08429902 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04449699 0,0842327 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,04449699 0,08416648 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04449699 0,08410036 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04449699 0,08403435 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04449699 0,08396844 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04449699 0,08390263 ! drug transport GO:0015893 16 12 0,000 0,04449699 0,08383693 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04449699 0,08377133 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04449699 0,08370583 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04449699 0,08364044 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04449699 0,08357514 ! focal adhesion formation GO:0048041 35 12 0,000 0,04449699 0,08350995 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04449699 0,08344486 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04449699 0,08337987 ! forebrain cell migration GO:0021885 21 12 0,000 0,04449699 0,08331499 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04449699 0,0832502 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04449699 0,08318552 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04449699 0,08312093 ! fear response GO:0042596 26 12 0,000 0,04449699 0,08305645 ! monoamine transport GO:0015844 18 12 0,000 0,04449699 0,08299206 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04449699 0,08292778 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04449699 0,08286359 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04449699 0,0827995 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04449699 0,08273552 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04449699 0,08267163 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04449699 0,08260784 ! protein homotetramerization GO:0051289 21 12 0,000 0,04449699 0,08254415 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04449699 0,08248055 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04449699 0,08241706 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04449699 0,08235366 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04449699 0,08229036 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04449699 0,08222716 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04449699 0,08216405 ! cranial nerve development GO:0021545 20 12 0,000 0,04449699 0,08210104 ! fucose catabolic process GO:0019317 22 12 0,000 0,04449699 0,08203813 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04449699 0,08197531 ! histone methylation GO:0016571 26 12 0,000 0,04449699 0,08191259 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04449699 0,08184997 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04449699 0,08178744 ! gland morphogenesis GO:0022612 29 12 0,000 0,04449699 0,08172501 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04449699 0,08166267 ! T cell homeostasis GO:0043029 25 12 0,000 0,04449699 0,08160043 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04449699 0,08153828 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04449699 0,08147622 ! spleen development GO:0048536 22 12 0,000 0,04449699 0,08141427 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04449699 0,0813524 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04449699 0,08129063 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04449699 0,08122895 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04449699 0,08116737 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04449699 0,08110588 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04449699 0,08104448 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04449699 0,08098318 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04449699 0,08092196 ! response to cold GO:0009409 17 12 0,000 0,04449699 0,08086084 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04449699 0,08079982 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04449699 0,08073888 ! cellular defense response GO:0006968 114 89 1,000 0,04493618 0,08147434 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,04584642 0,08306212 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04811524 0,08710704 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04811524 0,08704155 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04811524 0,08697615 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04811524 0,08691086 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04811524 0,08684566 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04811524 0,08678056 ! lipid localization GO:0010876 28 13 0,000 0,04811524 0,08671555 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04811524 0,08665065 ! organelle fusion GO:0048284 32 13 0,000 0,04811524 0,08658584 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04811524 0,08652112 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04811524 0,08645651 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04811524 0,08639199 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04811524 0,08632756 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04811524 0,08626324 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04811524 0,086199 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04811524 0,08613487 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04811524 0,08607083 ! methionine metabolic process GO:0006555 27 13 0,000 0,04811524 0,08600688 ! plasma membrane organization GO:0007009 24 13 0,000 0,04811524 0,08594303 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04811524 0,08587927 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04811524 0,08581561 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04811524 0,08575205 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04811524 0,08568857 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04811524 0,08562519 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04811524 0,08556191 ! exocrine system development GO:0035272 32 13 0,000 0,04811524 0,08549872 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04811524 0,08543562 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04811524 0,08537261 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04811524 0,0853097 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04811524 0,08524688 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04811524 0,08518415 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04811524 0,08512152 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04811524 0,08505897 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04811524 0,08499652 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04811524 0,08493416 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04811524 0,08487189 ! ribosome assembly GO:0042255 17 13 0,000 0,04811524 0,08480972 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,04811524 0,08474763 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04811524 0,08468563 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04811524 0,08462373 ! chromatin silencing GO:0006342 26 13 0,000 0,04811524 0,08456192 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04811524 0,08450019 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04811524 0,08443856 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04811524 0,08437701 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04811524 0,08431556 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04811524 0,08425419 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,04811524 0,08419292 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04811524 0,08413173 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04811524 0,08407063 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04811524 0,08400962 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04811524 0,0839487 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04811524 0,08388787 ! insulin secretion GO:0030073 23 13 0,000 0,04811524 0,08382713 ! actin filament polymerization GO:0030041 24 13 0,000 0,04811524 0,08376647 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04811524 0,0837059 ! acrosome reaction GO:0007340 18 13 0,000 0,04811524 0,08364542 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,04861766 0,08445783 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,04861766 0,08439689 ! female pregnancy GO:0007565 164 94 1,000 0,0495547 0,08596151 ! transcription initiation GO:0006352 153 94 1,000 0,0495547 0,08589958 ! mRNA transport GO:0051028 169 96 1,000 0,05144835 0,08911788 ! detection of stimulus GO:0051606 151 96 1,000 0,05144835 0,08905376 ! rRNA transcription GO:0009303 25 14 0,000 0,0517199 0,08945945 ! lactation GO:0007595 26 14 0,000 0,0517199 0,08939518 ! reproductive cellular process GO:0048610 20 14 0,000 0,0517199 0,089331 ! tRNA modification GO:0006400 20 14 0,000 0,0517199 0,08926692 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0517199 0,08920293 ! regulation of S phase GO:0033261 23 14 0,000 0,0517199 0,08913903 ! water transport GO:0006833 21 14 0,000 0,0517199 0,08907522 GO:0042044|fluid transport, ! non-recombinational repair GO:0000726 25 14 0,000 0,0517199 0,08901151 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0517199 0,08894788 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0517199 0,08888435 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0517199 0,08882091 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0517199 0,08875755 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0517199 0,08869429 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0517199 0,08863112 ! palate development GO:0060021 31 14 0,000 0,0517199 0,08856803 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0517199 0,08850504 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0517199 0,08844214 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0517199 0,08837932 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0517199 0,0883166 ! arginine metabolic process GO:0006525 17 14 0,000 0,0517199 0,08825396 ! regulation of heart rate GO:0002027 24 14 0,000 0,0517199 0,08819142 ! organic alcohol transport GO:0015850 29 14 0,000 0,0517199 0,08812896 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0517199 0,08806659 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0517199 0,08800431 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0517199 0,08794211 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0517199 0,08788001 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0517199 0,08781799 ! L-amino acid transport GO:0015807 30 14 0,000 0,0517199 0,08775606 ! bone mineralization GO:0030282 17 14 0,000 0,0517199 0,08769421 ! stem cell development GO:0048864 43 14 0,000 0,0517199 0,08763246 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0517199 0,08757079 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0517199 0,0875092 ! cerebellum development GO:0021549 21 14 0,000 0,0517199 0,08744771 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0517199 0,0873863 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0517199 0,08732497 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0517199 0,08726374 ! cofactor transport GO:0051181 26 14 0,000 0,0517199 0,08720258 ! NADP metabolic process GO:0006739 24 14 0,000 0,0517199 0,08714152 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0517199 0,08708054 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0517199 0,08701964 ! intestinal absorption GO:0050892 25 14 0,000 0,0517199 0,08695883 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0517199 0,08689811 ! oxygen transport GO:0015671 21 14 0,000 0,0517199 0,08683747 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0517199 0,08677691 ! male genitalia development GO:0030539 24 14 0,000 0,0517199 0,08671644 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0517199 0,08665605 ! regulation of axon extension GO:0030516 37 14 0,000 0,0517199 0,08659575 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0517199 0,08653553 ! protein ubiquitination GO:0016567 217 97 1,000 0,05240483 0,08762059 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05531104 0,09241553 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05531104 0,09235139 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,05531104 0,09228735 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,05531104 0,09222339 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05531104 0,09215953 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05531104 0,09209575 ! copper ion transport GO:0006825 20 15 0,000 0,05531104 0,09203206 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05531104 0,09196846 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05531104 0,09190494 ! sulfate transport GO:0008272 23 15 0,000 0,05531104 0,09184152 ! response to cAMP GO:0051591 22 15 0,000 0,05531104 0,09177818 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05531104 0,09171493 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05531104 0,09165176 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05531104 0,09158868 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05531104 0,09152569 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05531104 0,09146279 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05531104 0,09139997 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05531104 0,09133724 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05531104 0,09127459 ! pituitary gland development GO:0021983 29 15 0,000 0,05531104 0,09121203 ! vesicle coating GO:0006901 33 15 0,000 0,05531104 0,09114956 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05531104 0,09108717 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05531104 0,09102487 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05531104 0,09096265 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05531104 0,09090052 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05531104 0,09083847 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05531104 0,09077651 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05531104 0,09071463 ! histone deacetylation GO:0016575 20 15 0,000 0,05531104 0,09065283 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05531104 0,09059112 ! tissue regeneration GO:0042246 26 15 0,000 0,05531104 0,0905295 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05531104 0,09046795 ! water homeostasis GO:0030104 27 15 0,000 0,05531104 0,09040649 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05531104 0,09034512 ! muscle maintenance GO:0046716 26 15 0,000 0,05531104 0,09028383 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05531104 0,09022262 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05531104 0,09016149 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05531104 0,09010045 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05531104 0,09003948 ! cell killing GO:0001906 29 15 0,000 0,05531104 0,08997861 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,05531104 0,08991781 ! detection of bacterium GO:0016045 18 15 0,000 0,05531104 0,0898571 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,05531104 0,08979646 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05531104 0,08973591 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05531104 0,08967544 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05531104 0,08961506 ! peptide hormone processing GO:0016486 23 15 0,000 0,05531104 0,08955475 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,05888869 0,09528325 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,05888869 0,09521922 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05888869 0,09515527 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05888869 0,09509141 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05888869 0,09502763 ! bone remodeling GO:0046849 27 16 0,000 0,05888869 0,09496394 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05888869 0,09490033 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,05888869 0,09483681 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05888869 0,09477337 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,05888869 0,09471002 ! startle response GO:0001964 28 16 0,000 0,05888869 0,09464676 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05888869 0,09458357 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,05888869 0,09452048 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05888869 0,09445746 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,05888869 0,09439453 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05888869 0,09433169 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05888869 0,09426893 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05888869 0,09420625 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05888869 0,09414365 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05888869 0,09408114 ! response to osmotic stress GO:0006970 25 16 0,000 0,05888869 0,09401871 ! lysosomal transport GO:0007041 26 16 0,000 0,05888869 0,09395636 ! fructose metabolic process GO:0006000 25 16 0,000 0,05888869 0,0938941 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05888869 0,09383192 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05888869 0,09376982 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,05888869 0,0937078 ! negative regulation of immune response GO:0050777 35 16 0,000 0,05888869 0,09364587 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05888869 0,09358401 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05888869 0,09352224 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,05888869 0,09346055 ! DNA replication initiation GO:0006270 27 16 0,000 0,05888869 0,09339894 ! neuron recognition GO:0008038 35 16 0,000 0,05888869 0,09333741 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05888869 0,09327597 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05888869 0,0932146 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05888869 0,09315332 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05888869 0,09309211 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,05888869 0,09303099 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05888869 0,09296994 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05888869 0,09290898 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05888869 0,0928481 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05888869 0,09278729 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05888869 0,09272657 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05888869 0,09266592 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,05888869 0,09260536 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,05888869 0,09254487 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06245292 0,09808206 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06245292 0,09801808 ! metencephalon development GO:0022037 30 17 0,000 0,06245292 0,09795418 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,06245292 0,09789037 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06245292 0,09782664 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06245292 0,09776299 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06245292 0,09769943 ! signal complex assembly GO:0007172 41 17 0,000 0,06245292 0,09763594 ! endothelial cell migration GO:0043542 28 17 0,000 0,06245292 0,09757254 ! inositol metabolic process GO:0006020 28 17 0,000 0,06245292 0,09750923 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06245292 0,09744599 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06245292 0,09738284 ! glial cell development GO:0021782 27 17 0,000 0,06245292 0,09731976 ! limbic system development GO:0021761 36 17 0,000 0,06245292 0,09725677 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,06245292 0,09719387 ! adult walking behavior GO:0007628 33 17 0,000 0,06245292 0,09713104 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,06245292 0,09706829 ! heart looping GO:0001947 30 17 0,000 0,06245292 0,09700563 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06245292 0,09694304 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06245292 0,09688054 ! myoblast differentiation GO:0045445 45 17 0,000 0,06245292 0,09681812 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06245292 0,09675577 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,06245292 0,09669351 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06245292 0,09663133 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06245292 0,09656923 ! glycine metabolic process GO:0006544 28 17 0,000 0,06245292 0,0965072 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06245292 0,09644526 ! NAD metabolic process GO:0019674 29 17 0,000 0,06245292 0,0963834 ! membrane budding GO:0006900 37 17 0,000 0,06245292 0,09632161 ! DNA integration GO:0015074 29 17 0,000 0,06245292 0,09625991 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,06245292 0,09619828 ! regulation of protein binding GO:0043393 33 17 0,000 0,06245292 0,09613673 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06245292 0,09607527 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06245292 0,09601388 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06245292 0,09595256 ! genitalia development GO:0048806 30 17 0,000 0,06245292 0,09589133 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06245292 0,09583018 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,06245292 0,0957691 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,06245292 0,0957081 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06245292 0,09564718 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06245292 0,09558633 ! steroid catabolic process GO:0006706 31 17 0,000 0,06245292 0,09552557 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06245292 0,09546488 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,06245292 0,09540426 ! gas transport GO:0015669 25 17 0,000 0,06245292 0,09534373 ! organic cation transport GO:0015695 31 17 0,000 0,06245292 0,09528327 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06245292 0,09522289 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,06245292 0,09516258 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06245292 0,09510235 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,06245292 0,0950422 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06600376 0,10038245 ! neuron maturation GO:0042551 42 18 0,000 0,06600376 0,10031904 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06600376 0,10025571 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,06600376 0,10019246 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,06600376 0,10012928 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06600376 0,10006619 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06600376 0,10000318 ! memory GO:0007613 31 18 0,000 0,06600376 0,09994024 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06600376 0,09987739 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06600376 0,09981461 ! patterning of blood vessels GO:0001569 39 18 0,000 0,06600376 0,09975191 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,06600376 0,09968929 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,06600376 0,09962675 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,06600376 0,09956429 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,06600376 0,09950191 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06600376 0,0994396 ! response to retinoic acid GO:0032526 26 18 0,000 0,06600376 0,09937737 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,06600376 0,09931522 ! response to fungus GO:0009620 21 18 0,000 0,06600376 0,09925315 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,06600376 0,09919116 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,06600376 0,09912924 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,06600376 0,0990674 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,06600376 0,09900564 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06600376 0,09894395 ! vitamin transport GO:0051180 27 18 0,000 0,06600376 0,09888234 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,06600376 0,09882081 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06600376 0,09875936 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,06600376 0,09869798 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,06600376 0,09863667 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,06600376 0,09857545 ! nerve development GO:0021675 28 18 0,000 0,06600376 0,0985143 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06600376 0,09845322 ! protein secretion GO:0009306 39 19 0,000 0,06954127 0,10366561 ! positive regulation of translation GO:0045727 30 19 0,000 0,06954127 0,10360142 ! negative regulation of defense response GO:0031348 25 19 0,000 0,06954127 0,10353731 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,06954127 0,10347328 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,06954127 0,10340933 ! skin development GO:0043588 36 19 0,000 0,06954127 0,10334546 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,06954127 0,10328167 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06954127 0,10321795 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,06954127 0,10315431 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,06954127 0,10309076 ! bile acid metabolic process GO:0008206 29 19 0,000 0,06954127 0,10302728 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,06954127 0,10296388 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,06954127 0,10290055 ! cerebral cortex development GO:0021987 36 19 0,000 0,06954127 0,10283731 ! pigmentation during development GO:0048066 41 19 0,000 0,06954127 0,10277414 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,06954127 0,10271105 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,06954127 0,10264804 ! heme metabolic process GO:0042168 36 19 0,000 0,06954127 0,1025851 ! actin filament bundle formation GO:0051017 42 19 0,000 0,06954127 0,10252224 ! neuromuscular junction development GO:0007528 34 19 0,000 0,06954127 0,10245946 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,06954127 0,10239675 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,06954127 0,10233413 ! peptide cross-linking GO:0018149 37 19 0,000 0,06954127 0,10227158 ! protein export from nucleus GO:0006611 36 19 0,000 0,06954127 0,1022091 ! heart process GO:0003015 30 19 0,000 0,06954127 0,1021467 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,06954127 0,10208438 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,06954127 0,10202213 ! visual learning GO:0008542 36 19 0,000 0,06954127 0,10195996 ! cellular pigmentation GO:0033059 36 19 0,000 0,06954127 0,10189787 ! G1 phase GO:0051318 40 19 0,000 0,06954127 0,10183585 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,06954127 0,1017739 ! cell-cell junction organization GO:0045216 35 19 0,000 0,06954127 0,10171203 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,06954127 0,10165024 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,06954127 0,10158852 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,06954127 0,10152688 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,06954127 0,10146531 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,06954127 0,10140382 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,06954127 0,1013424 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,06954127 0,10128105 ! cilium assembly GO:0042384 37 19 0,000 0,06954127 0,10121978 ! peptide hormone secretion GO:0030072 31 19 0,000 0,06954127 0,10115858 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0730655 0,1062209 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,0730655 0,10615676 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0730655 0,1060927 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0730655 0,10602871 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0730655 0,1059648 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0730655 0,10590096 ! response to vitamin GO:0033273 31 20 0,000 0,0730655 0,1058372 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0730655 0,10577352 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0730655 0,10570992 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0730655 0,10564639 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0730655 0,10558294 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0730655 0,10551957 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0730655 0,10545627 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0730655 0,10539304 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0730655 0,1053299 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0730655 0,10526682 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0730655 0,10520383 ! body fluid secretion GO:0007589 31 20 0,000 0,0730655 0,10514091 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0730655 0,10507806 ! peptide secretion GO:0002790 35 20 0,000 0,0730655 0,10501529 ! stem cell differentiation GO:0048863 53 20 0,000 0,0730655 0,10495259 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0730655 0,10488997 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0730655 0,10482743 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0730655 0,10476496 ! sensory perception of pain GO:0019233 30 20 0,000 0,0730655 0,10470256 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0730655 0,10464024 ! diencephalon development GO:0021536 34 20 0,000 0,0730655 0,10457799 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0730655 0,10451581 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0730655 0,10445371 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0730655 0,10439168 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0730655 0,10432973 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0730655 0,10426785 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0730655 0,10420604 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0730655 0,10414431 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0730655 0,10408265 ! regulation of glucose import GO:0046324 29 20 0,000 0,0730655 0,10402106 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0730655 0,10395955 ! actin filament-based movement GO:0030048 43 20 0,000 0,0730655 0,10389811 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0730655 0,10383674 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,0730655 0,10377544 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0730655 0,10371422 ! negative regulation of translation GO:0017148 29 20 0,000 0,0730655 0,10365306 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0730655 0,10359198 ! regulation of cell killing GO:0031341 42 21 0,000 0,0765765 0,10850592 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,0765765 0,10844206 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,0765765 0,10837827 ! hormone secretion GO:0046879 38 21 0,000 0,0765765 0,10831456 ! glycerol metabolic process GO:0006071 34 21 0,000 0,0765765 0,10825092 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,0765765 0,10818735 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,0765765 0,10812386 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,0765765 0,10806045 ! ovarian follicle development GO:0001541 35 21 0,000 0,0765765 0,1079971 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,0765765 0,10793384 ! smooth muscle contraction GO:0006939 46 21 0,000 0,0765765 0,10787064 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,0765765 0,10780752 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,0765765 0,10774448 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,0765765 0,10768151 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,0765765 0,10761861 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,0765765 0,10755578 ! cytolysis GO:0019835 24 21 0,000 0,0765765 0,10749303 ! vasodilation GO:0042311 39 21 0,000 0,0765765 0,10743036 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,0765765 0,10736775 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,0765765 0,10730522 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,0765765 0,10724276 ! oogenesis GO:0048477 36 21 0,000 0,0765765 0,10718037 ! DNA modification GO:0006304 34 21 0,000 0,0765765 0,10711806 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,0765765 0,10705582 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,0765765 0,10699365 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,0765765 0,10693155 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,0765765 0,10686952 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,0765765 0,10680757 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,0765765 0,10674569 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,0765765 0,10668388 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,0765765 0,10662214 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,0765765 0,10656047 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,0765765 0,10649888 ! collagen catabolic process GO:0030574 28 21 0,000 0,0765765 0,10643735 ! sperm-egg recognition GO:0035036 21 21 0,000 0,0765765 0,1063759 ! gut development GO:0048565 39 21 0,000 0,0765765 0,10631452 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,08007432 0,11110658 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,08007432 0,11104254 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08007432 0,11097857 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08007432 0,11091468 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,08007432 0,11085087 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,08007432 0,11078712 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08007432 0,11072345 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,08007432 0,11065985 ! regeneration GO:0031099 41 22 0,000 0,08007432 0,11059633 ! keratinization GO:0031424 28 22 0,000 0,08007432 0,11053288 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,08007432 0,1104695 ! sensory perception of taste GO:0050909 28 22 0,000 0,08007432 0,11040619 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,08007432 0,11034296 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08007432 0,1102798 ! vacuolar transport GO:0007034 36 22 0,000 0,08007432 0,11021671 ! lysosome organization GO:0007040 41 22 0,000 0,08007432 0,11015369 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08007432 0,11009075 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,08007432 0,11002787 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,08007432 0,10996507 ! fucose metabolic process GO:0006004 39 22 0,000 0,08007432 0,10990234 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08007432 0,10983968 ! ureteric bud development GO:0001657 43 22 0,000 0,08007432 0,1097771 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,08007432 0,10971458 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,08007432 0,10965214 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,08007432 0,10958976 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,08007432 0,10952746 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08007432 0,10946523 ! sarcomere organization GO:0045214 30 22 0,000 0,08007432 0,10940307 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,08007432 0,10934098 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,08007432 0,10927896 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08007432 0,10921701 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,08007432 0,10915513 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,08007432 0,10909332 ! protein stabilization GO:0050821 39 22 0,000 0,08007432 0,10903158 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,083559 0,11371208 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,083559 0,1136478 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,083559 0,11358359 ! viral genome replication GO:0019079 41 23 0,000 0,083559 0,11351945 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,083559 0,11345539 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,083559 0,1133914 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,083559 0,11332748 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,083559 0,11326364 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,083559 0,11319986 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,083559 0,11313616 ! visual behavior GO:0007632 42 23 0,000 0,083559 0,11307253 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,083559 0,11300897 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,083559 0,11294548 ! response to ethanol GO:0045471 46 23 0,000 0,083559 0,11288206 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,083559 0,11281872 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,083559 0,11275544 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,083559 0,11269224 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,083559 0,1126291 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,083559 0,11256604 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,083559 0,11250305 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,083559 0,11244013 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,083559 0,11237728 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,083559 0,1123145 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,083559 0,11225179 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,083559 0,11218915 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,083559 0,11212658 ! fatty acid transport GO:0015908 44 23 0,000 0,083559 0,11206408 ! platelet activation GO:0030168 37 23 0,000 0,083559 0,11200164 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,083559 0,11193928 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,083559 0,11187699 ! hormone transport GO:0009914 40 23 0,000 0,083559 0,11181477 ! cell-cell recognition GO:0009988 25 23 0,000 0,083559 0,11175261 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,083559 0,11169053 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,083559 0,11162851 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,083559 0,11156657 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,083559 0,11150469 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,083559 0,11144288 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,0870306 0,11600865 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,0870306 0,11594442 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,0870306 0,11588025 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,0870306 0,11581616 ! vesicle docking GO:0048278 47 24 0,000 0,0870306 0,11575214 ! spinal cord development GO:0021510 47 24 0,000 0,0870306 0,11568819 ! vacuole organization GO:0007033 43 24 0,000 0,0870306 0,11562431 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,0870306 0,1155605 ! digestive system process GO:0022600 39 24 0,000 0,0870306 0,11549676 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,0870306 0,11543309 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,0870306 0,11536949 ! regulation of behavior GO:0050795 43 24 0,000 0,0870306 0,11530596 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,0870306 0,1152425 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,0870306 0,11517911 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,0870306 0,11511579 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,0870306 0,11505254 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,0870306 0,11498936 ! membrane depolarization GO:0051899 39 24 0,000 0,0870306 0,11492624 ! pallium development GO:0021543 49 24 0,000 0,0870306 0,1148632 ! pentose metabolic process GO:0019321 35 24 0,000 0,0870306 0,11480023 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,0870306 0,11473732 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,0870306 0,11467449 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,0870306 0,11461172 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,0870306 0,11454902 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,0870306 0,1144864 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,0870306 0,11442383 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,0870306 0,11436134 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,0870306 0,11429892 ! regulation of amine transport GO:0051952 40 24 0,000 0,0870306 0,11423656 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,09048916 0,11871151 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,09048916 0,11864682 ! myelination GO:0042552 45 25 0,000 0,09048916 0,1185822 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,09048916 0,11851765 ! phototransduction GO:0007602 33 25 0,000 0,09048916 0,11845317 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,09048916 0,11838875 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,09048916 0,11832441 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,09048916 0,11826014 ! receptor metabolic process GO:0043112 46 25 0,000 0,09048916 0,11819594 ! chromosome condensation GO:0030261 45 25 0,000 0,09048916 0,11813181 ! osteoblast differentiation GO:0001649 60 25 0,000 0,09048916 0,11806774 ! neural crest cell development GO:0014032 54 25 0,000 0,09048916 0,11800375 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,09048916 0,11793983 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,09048916 0,11787597 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,09048916 0,11781219 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,09048916 0,11774847 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,09048916 0,11768482 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,09048916 0,11762124 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,09048916 0,11755773 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,09048916 0,11749429 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,09048916 0,11743092 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,09048916 0,11736761 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,09048916 0,11730437 ! telomere organization GO:0032200 43 25 0,000 0,09048916 0,11724121 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,09048916 0,1171781 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,09048916 0,11711507 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,09393473 0,12150912 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,09393473 0,12144383 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,09393473 0,12137861 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,09393473 0,12131346 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,09393473 0,12124837 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,09393473 0,12118336 ! molting cycle process GO:0022404 50 26 0,000 0,09393473 0,12111842 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,09393473 0,12105355 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,09393473 0,12098874 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,09393473 0,12092401 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,09393473 0,12085934 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,09393473 0,12079475 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,09393473 0,12073022 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,09393473 0,12066576 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,09393473 0,12060137 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,09393473 0,12053705 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,09393473 0,1204728 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,09393473 0,12040862 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,09393473 0,1203445 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,09393473 0,12028045 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,09393473 0,12021647 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,09393473 0,12015256 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,09393473 0,12008872 ! leukocyte proliferation GO:0070661 52 26 0,000 0,09393473 0,12002494 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,09393473 0,11996124 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,09393473 0,1198976 ! neuron fate commitment GO:0048663 48 27 0,000 0,09736737 0,12421309 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,09736737 0,12414727 ! iron ion transport GO:0006826 59 27 0,000 0,09736737 0,12408151 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,09736737 0,12401582 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,09736737 0,12395021 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,09736737 0,12388466 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! fat cell differentiation GO:0045444 50 27 0,000 0,09736737 0,12381918 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,09736737 0,12375377 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,09736737 0,12368843 ! autophagy GO:0006914 41 27 0,000 0,09736737 0,12362316 ! male gonad development GO:0008584 44 27 0,000 0,09736737 0,12355796 ! response to toxin GO:0009636 47 27 0,000 0,09736737 0,12349283 ! primary neural tube formation GO:0014020 51 27 0,000 0,09736737 0,12342776 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,09736737 0,12336277 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,09736737 0,12329784 ! glutathione metabolic process GO:0006749 39 27 0,000 0,09736737 0,12323298 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,09736737 0,12316819 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,09736737 0,12310346 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,09736737 0,12303881 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,09736737 0,12297422 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,10078711 0,12722655 ! circadian rhythm GO:0007623 50 28 0,000 0,10078711 0,12715983 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,10078711 0,12709319 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,10078711 0,12702661 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,10078711 0,1269601 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,10078711 0,12689367 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,10078711 0,1268273 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,10078711 0,126761 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,10078711 0,12669477 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,10078711 0,12662862 ! synaptogenesis GO:0007416 42 28 0,000 0,10078711 0,12656253 ! lipid oxidation GO:0034440 43 28 0,000 0,10078711 0,1264965 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,10078711 0,12643055 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,10078711 0,12636467 ! translational initiation GO:0006413 65 29 0,000 0,10419402 0,13056813 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,10419402 0,13050016 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,10419402 0,13043226 ! catechol metabolic process GO:0009712 54 29 0,000 0,10419402 0,13036443 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,10419402 0,13029668 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,10419402 0,13022899 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,10419402 0,13016137 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,10419402 0,13009383 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,10419402 0,13002635 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,10419402 0,12995894 ! cell fate determination GO:0001709 60 29 0,000 0,10419402 0,12989161 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,10419402 0,12982434 ! detection of light stimulus GO:0009583 38 29 0,000 0,10419402 0,12975714 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,10419402 0,12969002 ! tissue homeostasis GO:0001894 48 29 0,000 0,10419402 0,12962296 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,10419402 0,12955597 ! phenol metabolic process GO:0018958 55 30 0,000 0,10758812 0,13370714 ! zinc ion transport GO:0006829 45 30 0,000 0,10758812 0,13363811 ! membrane docking GO:0022406 61 30 0,000 0,10758812 0,13356916 ! cell junction assembly GO:0034329 78 30 0,000 0,10758812 0,13350027 ! regulation of innate immune response GO:0045088 51 30 0,000 0,10758812 0,13343146 ! acute-phase response GO:0006953 49 30 0,000 0,10758812 0,13336271 ! myofibril assembly GO:0030239 47 30 0,000 0,10758812 0,13329404 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,10758812 0,13322544 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,10758812 0,13315691 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,10758812 0,13308844 ! phospholipid transport GO:0015914 51 30 0,000 0,10758812 0,13302005 ! ensheathment of neurons GO:0007272 57 30 0,000 0,10758812 0,13295173 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,10758812 0,13288348 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,10758812 0,1328153 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,10758812 0,13274719 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,10758812 0,13267915 ! eye morphogenesis GO:0048592 60 30 0,000 0,10758812 0,13261118 ! regulation of B cell activation GO:0050864 50 30 0,000 0,10758812 0,13254328 ! response to heat GO:0009408 50 30 0,000 0,10758812 0,13247545 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,11096948 0,13656909 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,11096948 0,13649927 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,11096948 0,13642952 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,11096948 0,13635984 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,11096948 0,13629024 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,11096948 0,1362207 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,11096948 0,13615124 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,11096948 0,13608184 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,11096948 0,13601252 ! ovulation cycle process GO:0022602 49 31 0,000 0,11096948 0,13594327 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,11096948 0,13587408 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,11096948 0,13580497 ! peptide transport GO:0015833 55 31 0,000 0,11096948 0,13573593 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,11096948 0,13566696 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,11096948 0,13559806 ! mesoderm formation GO:0001707 69 31 0,000 0,11096948 0,13552923 ! natural killer cell activation GO:0030101 45 31 0,000 0,11096948 0,13546046 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,11096948 0,13539177 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,11096948 0,13532315 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,11096948 0,1352546 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,11096948 0,13518611 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,11096948 0,1351177 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,11433814 0,139149 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,11433814 0,13907865 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,11433814 0,13900837 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,11433814 0,13893817 ! cholesterol transport GO:0030301 56 32 0,000 0,11433814 0,13886803 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,11433814 0,13879797 ! spliceosome assembly GO:0000245 67 32 0,000 0,11433814 0,13872797 ! spindle organization GO:0007051 46 32 0,000 0,11433814 0,13865805 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,11433814 0,1385882 ! metanephros development GO:0001656 74 32 0,000 0,11433814 0,13851841 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,11433814 0,1384487 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,11433814 0,13837906 ! muscle cell development GO:0055001 49 32 0,000 0,11433814 0,13830949 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,11433814 0,13823998 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,11433814 0,13817055 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,11433814 0,13810119 ! ovulation cycle GO:0042698 51 32 0,000 0,11433814 0,1380319 ! peripheral nervous system development GO:0007422 64 32 0,000 0,11433814 0,13796267 ! BMP signaling pathway GO:0030509 64 32 0,000 0,11433814 0,13789352 ! hindbrain development GO:0030902 61 32 0,000 0,11433814 0,13782443 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,11433814 0,13775542 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,11433814 0,13768647 ! gene silencing GO:0016458 65 32 0,000 0,11433814 0,13761759 ! post-embryonic development GO:0009791 69 33 0,000 0,11769415 0,14158606 ! protein targeting to membrane GO:0006612 68 33 0,000 0,11769415 0,1415153 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,11769415 0,14144462 ! ceramide metabolic process GO:0006672 64 33 0,000 0,11769415 0,141374 ! formation of primary germ layer GO:0001704 72 33 0,000 0,11769415 0,14130345 ! cell fate specification GO:0001708 52 33 0,000 0,11769415 0,14123298 ! sterol transport GO:0015918 57 33 0,000 0,11769415 0,14116257 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,11769415 0,14109224 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,11769415 0,14102197 ! adult locomotory behavior GO:0008344 59 33 0,000 0,11769415 0,14095178 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,11769415 0,14088165 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,12103755 0,14481171 ! glial cell differentiation GO:0010001 63 34 0,000 0,12103755 0,14473973 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,12103755 0,14466783 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,12103755 0,144596 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,12103755 0,14452424 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,12103755 0,14445255 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,12103755 0,14438093 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,12103755 0,14430939 ! mismatch repair GO:0006298 46 34 0,000 0,12103755 0,14423791 ! spermatid development GO:0007286 63 34 0,000 0,12103755 0,14416651 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,12103755 0,14409517 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,12103755 0,14402391 ! regulation of muscle development GO:0048634 70 35 0,000 0,12436839 0,14791416 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,12436839 0,14784108 ! negative regulation of secretion GO:0051048 63 35 0,000 0,12436839 0,14776807 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,12436839 0,14769514 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,12436839 0,14762227 ! odontogenesis GO:0042476 66 35 0,000 0,12436839 0,14754948 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,12436839 0,14747676 ! female gonad development GO:0008585 58 35 0,000 0,12436839 0,14740411 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,12436839 0,14733154 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,12436839 0,14725903 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,12436839 0,1471866 ! cytokine production GO:0001816 59 35 0,000 0,12436839 0,14711423 ! neural tube formation GO:0001841 67 35 0,000 0,12436839 0,14704194 ! vesicle localization GO:0051648 64 35 0,000 0,12436839 0,14696972 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,12768672 0,15081701 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,12768672 0,15074301 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,12768672 0,15066908 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,12768672 0,15059522 ! cell junction organization GO:0034330 86 36 0,000 0,12768672 0,15052144 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,12768672 0,15044772 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,12768672 0,15037408 ! positive regulation of cell development GO:0010720 80 36 0,000 0,12768672 0,15030051 ! regulation of proteolysis GO:0030162 72 36 0,000 0,12768672 0,15022702 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,12768672 0,15015359 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,12768672 0,15008024 ! aerobic respiration GO:0009060 55 36 0,000 0,12768672 0,15000696 ! embryonic organ development GO:0048568 57 36 0,000 0,12768672 0,14993375 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,12768672 0,14986061 ! RNA export from nucleus GO:0006405 56 37 0,000 0,13099259 0,15366561 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,13099259 0,15359072 ! meiosis I GO:0007127 65 37 0,000 0,13099259 0,15351591 ! sister chromatid segregation GO:0000819 58 37 0,000 0,13099259 0,15344117 ! actomyosin structure organization GO:0031032 62 37 0,000 0,13099259 0,1533665 ! organic anion transport GO:0015711 68 37 0,000 0,13099259 0,15329191 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,13099259 0,15321738 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,13099259 0,15314294 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,13099259 0,15306856 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,13099259 0,15299425 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,13099259 0,15292002 ! pigment metabolic process GO:0042440 80 37 0,000 0,13099259 0,15284586 ! spermatid differentiation GO:0048515 66 37 0,000 0,13099259 0,15277177 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,13428603 0,15653691 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,13428603 0,15646111 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,13428603 0,15638538 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,13428603 0,15630972 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,13428603 0,15623413 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,13428603 0,15615862 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,13428603 0,15608318 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,13428603 0,15600782 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,13428603 0,15593252 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,13428603 0,1558573 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,13428603 0,15578216 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,13428603 0,15570708 ! mRNA catabolic process GO:0006402 71 39 0,000 0,1375671 0,15943471 ! mammary gland development GO:0030879 86 39 0,000 0,1375671 0,15935795 ! learning GO:0007612 77 39 0,000 0,1375671 0,15928126 ! organic ether metabolic process GO:0018904 55 39 0,000 0,1375671 0,15920464 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,1375671 0,1591281 ! ion transmembrane transport GO:0034220 66 39 0,000 0,1375671 0,15905163 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,1375671 0,15897524 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,1375671 0,15889892 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,1375671 0,15882267 ! RNA modification GO:0009451 57 39 0,000 0,1375671 0,1587465 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,1375671 0,1586704 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,14083585 0,16236275 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,14083585 0,16228499 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,14083585 0,1622073 ! feeding behavior GO:0007631 59 40 0,000 0,14083585 0,16212969 ! negative regulation of binding GO:0051100 72 40 0,000 0,14083585 0,16205215 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,14083585 0,16197469 ! mesenchymal cell development GO:0014031 87 40 0,000 0,14083585 0,1618973 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,14083585 0,16181999 ! maintenance of protein location GO:0045185 91 40 0,000 0,14083585 0,16174275 ! cytokinesis GO:0000910 72 40 0,000 0,14083585 0,16166558 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,14409232 0,1653248 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,14409232 0,165246 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,14409232 0,16516728 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,14409232 0,16508862 ! gliogenesis GO:0042063 88 41 0,000 0,14409232 0,16501005 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,14409232 0,16493155 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,14409232 0,16485312 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,14409232 0,16477477 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,14409232 0,16469649 ! female gamete generation GO:0007292 61 41 0,000 0,14409232 0,16461829 ! polyol metabolic process GO:0019751 66 41 0,000 0,14409232 0,16454016 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,14409232 0,1644621 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,14733655 0,16808522 ! regulation of tube size GO:0035150 71 42 0,000 0,14733655 0,16800556 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,14733655 0,16792597 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,14733655 0,16784646 ! neuron migration GO:0001764 79 42 0,000 0,14733655 0,16776703 ! regulation of protein secretion GO:0050708 71 42 0,000 0,14733655 0,16768767 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,14733655 0,16760838 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,15056859 0,17120417 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,15056859 0,1711233 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,15056859 0,1710425 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,15056859 0,17096178 ! glucose transport GO:0015758 65 43 0,000 0,15056859 0,17088114 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,15056859 0,17080058 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,15056859 0,17072009 ! neural tube development GO:0021915 77 43 0,000 0,15056859 0,17063967 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,15056859 0,17055933 ! striated muscle contraction GO:0006941 77 43 0,000 0,15056859 0,17047907 ! phagocytosis GO:0006909 90 43 0,000 0,15056859 0,17039888 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,15056859 0,17031877 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,15378848 0,17387927 ! hexose transport GO:0008645 67 44 0,000 0,15378848 0,1737976 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,15378848 0,17371601 ! male sex differentiation GO:0046661 76 44 0,000 0,15378848 0,17363449 ! biopolymer methylation GO:0043414 84 44 0,000 0,15378848 0,17355305 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,15378848 0,17347168 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,15378848 0,17339039 ! developmental growth GO:0048589 82 44 0,000 0,15378848 0,17330918 ! maintenance of location in cell GO:0051651 97 44 0,000 0,15378848 0,17322804 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,15699628 0,17675857 ! glycolysis GO:0006096 65 45 0,000 0,15699628 0,17667589 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,15699628 0,17659329 ! leukocyte migration GO:0050900 68 45 0,000 0,15699628 0,17651077 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,15699628 0,17642833 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,15699628 0,17634596 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,15699628 0,17626367 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,15699628 0,17618146 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,15699628 0,17609933 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,15699628 0,17601727 ! cell growth GO:0016049 84 45 0,000 0,15699628 0,17593528 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,16019203 0,17943297 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,16019203 0,17934947 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,16019203 0,17926605 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,16019203 0,17918271 ! positive regulation of defense response GO:0031349 76 47 0,000 0,16337576 0,18265896 ! response to calcium ion GO:0051592 81 47 0,000 0,16337576 0,18257412 ! endosome transport GO:0016197 108 47 0,000 0,16337576 0,18248936 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,16337576 0,18240468 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,16337576 0,18232008 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,16337576 0,18223555 ! JNK cascade GO:0007254 91 47 0,000 0,16337576 0,1821511 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,16337576 0,18206674 ! methylation GO:0032259 90 47 0,000 0,16337576 0,18198245 ! protein homooligomerization GO:0051260 76 47 0,000 0,16337576 0,18189823 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,16654753 0,18534383 ! Notch signaling pathway GO:0007219 96 48 0,000 0,16654753 0,18525814 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,16654753 0,18517253 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,16654753 0,185087 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,16654753 0,18500155 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,16654753 0,18491618 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,16654753 0,18483089 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,16654753 0,18474567 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,16654753 0,18466054 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,16970739 0,18807737 ! regulation of action potential GO:0001508 95 49 0,000 0,16970739 0,18799078 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,16970739 0,18790427 ! regulation of ion transport GO:0043269 77 49 0,000 0,16970739 0,18781783 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,16970739 0,18773148 ! peptide metabolic process GO:0006518 76 49 0,000 0,16970739 0,18764521 ! response to temperature stimulus GO:0009266 76 49 0,000 0,16970739 0,18755901 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,16970739 0,1874729 ! endocrine system development GO:0035270 104 49 0,000 0,16970739 0,18738686 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,16970739 0,1873009 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,16970739 0,18721502 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,16970739 0,18712922 ! neuromuscular process GO:0050905 99 50 0,000 0,17285536 0,19051306 ! regulation of ossification GO:0030278 117 50 0,000 0,17285536 0,19042582 ! inner ear development GO:0048839 79 50 0,000 0,17285536 0,19033867 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,17285536 0,1902516 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,17285536 0,19016461 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,17285536 0,1900777 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,17599151 0,1934379 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,17599151 0,19334957 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,17599151 0,19326133 ! excretion GO:0007588 83 51 0,000 0,17599151 0,19317316 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,17599151 0,19308507 ! chromatin remodeling GO:0006338 109 51 0,000 0,17599151 0,19299707 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,17599151 0,19290914 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,17599151 0,1928213 ! vesicle organization GO:0016050 107 51 0,000 0,17599151 0,19273353 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,17599151 0,19264584 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,17599151 0,19255824 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,17911587 0,19588762 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,17911587 0,19579862 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,17911587 0,19570971 ! amino acid activation GO:0043038 92 52 0,000 0,17911587 0,19562087 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,17911587 0,19553211 ! synapse organization GO:0050808 85 52 0,000 0,17911587 0,19544343 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,18222848 0,19874965 ! RNA catabolic process GO:0006401 93 53 0,000 0,18222848 0,1986596 ! regulation of translational initiation GO:0006446 82 53 0,000 0,18222848 0,19856962 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,18222848 0,19847973 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,18222848 0,19838992 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,18222848 0,19830019 ! cell maturation GO:0048469 100 53 0,000 0,18222848 0,19821055 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,18222848 0,19812098 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,1853294 0,20140132 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,1853294 0,2013104 ! cell recognition GO:0008037 85 54 0,000 0,1853294 0,20121955 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,1853294 0,20112879 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,1853294 0,20103811 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,1853294 0,20094751 ! chloride transport GO:0006821 90 55 0,000 0,18841866 0,20420509 ! glucose catabolic process GO:0006007 82 55 0,000 0,18841866 0,20411314 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,18841866 0,20402128 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,18841866 0,20392951 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,18841866 0,20383781 ! gastrulation GO:0007369 112 55 0,000 0,18841866 0,2037462 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,18841866 0,20365467 ! RNA elongation GO:0006354 79 55 0,000 0,18841866 0,20356322 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,18841866 0,20347186 ! regulation of actin filament length GO:0030832 105 56 0,000 0,19149631 0,20670261 ! sensory perception of smell GO:0007608 80 56 0,000 0,19149631 0,20660992 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,19149631 0,20651731 ! proton transport GO:0015992 94 56 0,000 0,19149631 0,20642478 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,19149631 0,20633234 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,19456239 0,20954212 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,19456239 0,20944837 ! maintenance of location GO:0051235 118 57 0,000 0,19456239 0,2093547 ! hydrogen transport GO:0006818 97 58 0,000 0,19761694 0,21254643 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,19761694 0,21245146 ! regulation of endocytosis GO:0030100 91 58 0,000 0,19761694 0,21235657 ! adult behavior GO:0030534 99 58 0,000 0,19761694 0,21226177 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,19761694 0,21216705 ! positive regulation of secretion GO:0051047 95 59 0,000 0,20066001 0,21533809 ! regulation of cellular component size GO:0032535 109 59 0,000 0,20066001 0,21524208 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,20066001 0,21514616 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,20066001 0,21505033 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,20369164 0,21820218 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,20369164 0,21810507 ! regulation of heart contraction GO:0008016 110 60 0,000 0,20369164 0,21800805 ! camera-type eye development GO:0043010 116 60 0,000 0,20369164 0,21791111 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,20369164 0,21781426 ! kidney development GO:0001822 122 60 0,000 0,20369164 0,2177175 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,20671188 0,22084759 ! mesoderm development GO:0007498 119 61 0,000 0,20671188 0,22074957 ! tRNA processing GO:0008033 89 61 0,000 0,20671188 0,22065163 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,20671188 0,22055378 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,20972075 0,22366495 ! gonad development GO:0008406 98 62 0,000 0,20972075 0,22356586 ! regulation of mitosis GO:0007088 105 63 0,000 0,21271832 0,22666088 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,21271832 0,22656055 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,21271832 0,2264603 ! cell redox homeostasis GO:0045454 102 64 0,000 0,21570462 0,22953795 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,21570462 0,22943647 ! single fertilization GO:0007338 75 64 0,000 0,21570462 0,22933509 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,21867968 0,23239546 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,21867968 0,23229285 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,21867968 0,23219034 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,21867968 0,23208792 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,22164356 0,23512981 ! actin filament organization GO:0007015 148 66 0,000 0,22164356 0,23502618 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,22164356 0,23492265 ! extracellular matrix organization GO:0030198 133 66 0,000 0,22164356 0,2348192 ! secondary metabolic process GO:0019748 116 66 0,000 0,22164356 0,23471585 ! developmental maturation GO:0021700 116 66 0,000 0,22164356 0,23461259 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,2245963 0,23763355 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,2245963 0,23752909 ! chromosome segregation GO:0007059 113 67 0,000 0,2245963 0,23742473 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,2245963 0,23732046 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,2245963 0,23721628 ! hexose catabolic process GO:0019320 104 67 0,000 0,2245963 0,23711219 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,2245963 0,2370082 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,2245963 0,23690429 ! adaptive immune response GO:0002250 119 67 0,000 0,2245963 0,23680048 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,2245963 0,23669675 ! amino acid transport GO:0006865 125 68 0,000 0,22753793 0,23969188 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,22753793 0,23958698 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,22753793 0,23948218 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 0,000 0,22753793 0,23937746 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,22753793 0,23927284 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,22753793 0,23916831 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,2304685 0,24214288 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,2304685 0,24203719 ! urogenital system development GO:0001655 137 69 0,000 0,2304685 0,24193159 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,2304685 0,24182608 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,2304685 0,24172066 ! antigen processing and presentation GO:0019882 104 69 0,000 0,2304685 0,24161534 ! appendage morphogenesis GO:0035107 135 70 0,000 0,23338805 0,24456953 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,23629661 0,24750964 ! reproductive structure development GO:0048608 113 71 0,000 0,23629661 0,24740194 ! appendage development GO:0048736 136 71 0,000 0,23629661 0,24729432 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,23629661 0,24718681 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,23629661 0,24707938 ! regulation of immune effector process GO:0002697 137 71 0,000 0,23629661 0,24697205 ! acute inflammatory response GO:0002526 113 72 0,000 0,23919424 0,24989203 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,23919424 0,24978357 ! carbohydrate transport GO:0008643 110 72 0,000 0,23919424 0,24967521 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,23919424 0,24956693 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,23919424 0,24945876 ! learning or memory GO:0007611 147 73 0,000 0,24208098 0,25235998 ! regulation of blood pressure GO:0008217 125 73 0,000 0,24208098 0,25225068 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,24208098 0,25214148 ! axon guidance GO:0007411 139 73 0,000 0,24208098 0,25203238 ! fertilization GO:0009566 90 73 0,000 0,24208098 0,25192337 ! transition metal ion transport GO:0000041 126 74 0,000 0,24495685 0,25480596 ! neurotransmitter transport GO:0006836 123 74 0,000 0,24495685 0,25469584 ! meiosis GO:0007126 121 74 0,000 0,24495685 0,25458582 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,24495685 0,2544759 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,24495685 0,25436607 ! eye development GO:0001654 143 74 0,000 0,24495685 0,25425633 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,24782191 0,25711924 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,24782191 0,25700841 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,24782191 0,25689768 ! meiotic cell cycle GO:0051321 122 75 0,000 0,24782191 0,25678704 ! rhythmic process GO:0048511 128 75 0,000 0,24782191 0,2566765 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,25067619 0,25952104 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,25067619 0,25940942 ! defense response to bacterium GO:0042742 89 76 0,000 0,25067619 0,2592979 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,25067619 0,25918647 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,25067619 0,25907513 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,25351973 0,26190145 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,25351973 0,26178905 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,25351973 0,26167674 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,25351973 0,26156453 ! blood coagulation GO:0007596 146 78 0,000 0,25635258 0,2643739 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,25635258 0,26426063 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,25635258 0,26414746 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,25917477 0,26694114 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,25917477 0,26682692 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,25917477 0,26671279 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,25917477 0,26659876 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,25917477 0,26648483 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,26198635 0,26926064 ! response to metal ion GO:0010038 140 80 0,000 0,26198635 0,26914567 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,26198635 0,26903079 ! inorganic anion transport GO:0015698 138 80 0,000 0,26198635 0,26891602 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,26478734 0,2716752 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 0,000 0,26478734 0,2715594 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,26478734 0,27144369 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,2675778 0,27418748 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,2675778 0,27407075 ! response to nutrient GO:0007584 125 82 0,000 0,2675778 0,27395413 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,2675778 0,2738376 ! regulation of lyase activity GO:0051339 160 83 0,000 0,27035776 0,27656496 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,27312727 0,2792793 ! hemostasis GO:0007599 158 84 0,000 0,27312727 0,27916066 ! regulation of ligase activity GO:0051340 142 84 0,000 0,27312727 0,27904212 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,27312727 0,27892368 ! response to unfolded protein GO:0006986 131 85 0,000 0,27588635 0,28162179 ! nucleosome assembly GO:0006334 122 85 0,000 0,27588635 0,28150235 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,27588635 0,28138302 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,27588635 0,28126379 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,27863505 0,28394575 ! response to inorganic substance GO:0010035 153 86 0,000 0,27863505 0,28382554 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,27863505 0,28370543 ! chromatin assembly GO:0031497 124 86 0,000 0,27863505 0,28358542 ! tube morphogenesis GO:0035239 176 86 0,000 0,27863505 0,28346551 ! alcohol catabolic process GO:0046164 130 86 0,000 0,27863505 0,2833457 ! amine transport GO:0015837 155 86 0,000 0,27863505 0,28322599 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,2813734 0,28588869 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,2813734 0,28576801 ! cellular respiration GO:0045333 135 88 0,000 0,28410146 0,28841692 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,28410146 0,28829528 ! gland development GO:0048732 206 88 0,000 0,28410146 0,28817374 ! regulation of neurological system process GO:0031644 148 88 0,000 0,28410146 0,2880523 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,28410146 0,28793096 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,28681924 0,29056299 ! ossification GO:0001503 188 90 0,000 0,2895268 0,29318245 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,2895268 0,2930591 ! sex differentiation GO:0007548 145 90 0,000 0,2895268 0,29293587 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,2895268 0,29281273 ! bone development GO:0060348 189 91 0,000 0,29222417 0,29541654 ! sterol metabolic process GO:0016125 152 91 0,000 0,29222417 0,29529247 ! response to protein stimulus GO:0051789 149 91 0,000 0,29222417 0,2951685 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,29222417 0,29504463 ! regulation of defense response GO:0031347 149 92 0,000 0,29491139 0,29763289 ! nucleosome organization GO:0034728 138 92 0,000 0,29491139 0,2975081 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,29491139 0,29738341 ! vitamin metabolic process GO:0006766 139 92 0,000 0,29491139 0,29725882 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,2975885 0,29983163 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,2975885 0,29970612 ! regulation of membrane potential GO:0042391 164 93 0,000 0,2975885 0,29958072 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,2975885 0,29945543 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,30025553 0,30201288 ! regulation of T cell activation GO:0050863 158 94 0,000 0,30025553 0,30188667 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,30291252 0,30443088 ! forebrain development GO:0030900 188 95 0,000 0,30291252 0,30430377 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,30291252 0,30417676 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,30555951 0,3067068 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,30555951 0,30657889 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,30819654 0,30909582 ! hormone metabolic process GO:0042445 157 97 0,000 0,30819654 0,30896703 ! response to virus GO:0009615 160 98 0,000 0,31082364 0,31147092 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,31082364 0,31134125 ! interphase GO:0051325 213 98 0,000 0,31082364 0,31121169 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,31082364 0,31108223 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,31344086 0,31357118 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,31344086 0,31344086