pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1143-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! release of cytochrome c from mitochondria GO:0001836 23 14 3,000 2,035E-07 4,68E-04 ! apoptotic mitochondrial changes GO:0008637 29 18 3,000 6,148E-07 7,07E-04 ! nucleosome organization GO:0034728 114 87 5,000 1,09E-06 8,36E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 3,109E-06 1,787E-03 ! chromatin assembly GO:0031497 102 80 4,000 1,471E-05 6,766E-03 GO:0006334|nucleosome assembly, ! induction of apoptosis by intracellular signals GO:0008629 67 40 3,000 1,722E-05 6,599E-03 ! protein-DNA complex assembly GO:0065004 107 84 4,000 1,866E-05 6,133E-03 ! regulation of gene-specific transcription GO:0032583 69 43 3,000 2,304E-05 6,625E-03 ! positive regulation of growth GO:0045927 67 50 3,000 4,213E-05 0,01076707 ! DNA damage response, signal transduction GO:0042770 96 56 3,000 6,603E-05 0,01518586 ! protein tetramerization GO:0051262 39 22 2,000 8,221E-05 0,01718968 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 9,428E-05 0,01807038 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 2,000 9,428E-05 0,01668035 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 1,074E-04 0,01765237 ! regulation of caspase activity GO:0043281 97 65 3,000 1,185E-04 0,0181776 ! peptidyl-tyrosine modification GO:0018212 37 25 2,000 1,218E-04 0,01750326 ! regulation of endopeptidase activity GO:0052548 99 67 3,000 1,334E-04 0,01805217 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 1,48E-04 0,01890597 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 1,48E-04 0,01791091 ! positive regulation of glycolysis GO:0045821 11 5 1,000 1,48E-04 0,01701537 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 1,48E-04 0,01620511 ! microvillus organization GO:0032528 7 5 1,000 1,48E-04 0,01546852 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 1,000 1,48E-04 0,01479597 ! regulation of respiratory burst GO:0060263 8 5 1,000 1,48E-04 0,01417947 ! regulation of peptidase activity GO:0052547 106 72 3,000 1,765E-04 0,01623776 ! mitochondrion organization GO:0007005 104 73 3,000 1,862E-04 0,01647021 ! cellular response to hormone stimulus GO:0032870 109 74 3,000 1,963E-04 0,01671765 ! regulation of helicase activity GO:0051095 11 6 1,000 2,214E-04 0,0181849 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 2,214E-04 0,01755783 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 2,214E-04 0,01697257 ! ER overload response GO:0006983 7 6 1,000 2,214E-04 0,01642507 ! male sex determination GO:0030238 9 6 1,000 2,214E-04 0,01591179 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 2,214E-04 0,01542961 ! DNA damage checkpoint GO:0000077 53 31 2,000 2,34E-04 0,01583105 ! positive regulation of gene-specific transcription GO:0043193 47 31 2,000 2,34E-04 0,01537873 ! negative regulation of hydrolase activity GO:0051346 50 33 2,000 2,825E-04 0,0180474 ! mitotic cell cycle checkpoint GO:0007093 63 34 2,000 3,09E-04 0,01920547 ! DNA integrity checkpoint GO:0031570 57 34 2,000 3,09E-04 0,01870006 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 3,09E-04 0,01822057 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 3,092E-04 0,01777639 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 3,092E-04 0,01734282 ! protein heterooligomerization GO:0051291 10 7 1,000 3,092E-04 0,0169299 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 3,092E-04 0,01653618 ! B cell lineage commitment GO:0002326 17 7 1,000 3,092E-04 0,01616036 ! T cell lineage commitment GO:0002360 12 7 1,000 3,092E-04 0,01580124 ! response to tumor cell GO:0002347 12 7 1,000 3,092E-04 0,01545773 ! trophectodermal cell differentiation GO:0001829 8 7 1,000 3,092E-04 0,01512884 ! regulation of DNA metabolic process GO:0051052 135 85 3,000 3,344E-04 0,01602546 ! succinate metabolic process GO:0006105 14 8 1,000 4,112E-04 0,01929982 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 4,112E-04 0,01891382 ! keratinocyte proliferation GO:0043616 12 8 1,000 4,112E-04 0,01854296 ! middle ear morphogenesis GO:0042474 9 8 1,000 4,112E-04 0,01818637 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 4,112E-04 0,01784323 ! nucleosome disassembly GO:0006337 12 8 1,000 4,112E-04 0,0175128 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! regulation of telomere maintenance GO:0032204 10 8 1,000 4,112E-04 0,01719438 ! regulation of embryonic development GO:0045995 16 8 1,000 4,112E-04 0,01688734 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 4,712E-04 0,01901152 ! T cell differentiation GO:0030217 65 40 2,000 5,017E-04 0,01989396 ! regulation of developmental growth GO:0048638 13 9 1,000 5,273E-04 0,02055649 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 5,273E-04 0,02021388 ! regulation of glycolysis GO:0006110 15 9 1,000 5,273E-04 0,01988251 ! phosphagen metabolic process GO:0006599 12 9 1,000 5,273E-04 0,01956182 GO:0006600|creatine metabolic process, ! blastocyst formation GO:0001825 12 9 1,000 5,273E-04 0,01925132 ! embryonic placenta development GO:0001892 12 9 1,000 5,273E-04 0,01895051 ! cellular component disassembly GO:0022411 64 42 2,000 5,797E-04 0,02051199 ! activation of caspase activity GO:0006919 65 43 2,000 6,214E-04 0,02165607 ! response to insulin stimulus GO:0032868 63 43 2,000 6,214E-04 0,02133284 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 6,575E-04 0,02223871 ! response to X-ray GO:0010165 16 10 1,000 6,575E-04 0,02191641 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 6,575E-04 0,02160332 ! DNA methylation GO:0006306 15 10 1,000 6,575E-04 0,02129905 GO:0006305|DNA alkylation, ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 6,575E-04 0,02100323 GO:0043470|regulation of carbohydrate catabolic process, ! histone modification GO:0016570 68 46 2,000 7,581E-04 0,02388387 ! virus-host interaction GO:0019048 17 11 1,000 8,016E-04 0,02491408 ! detection of mechanical stimulus GO:0050982 15 11 1,000 8,016E-04 0,02458189 ! regulation of intracellular pH GO:0051453 17 11 1,000 8,016E-04 0,02425844 ! histone deacetylation GO:0016575 13 11 1,000 8,016E-04 0,0239434 ! covalent chromatin modification GO:0016569 75 47 2,000 8,075E-04 0,02381073 ! positive regulation of caspase activity GO:0043280 72 48 2,000 8,589E-04 0,02500712 GO:0010952|positive regulation of peptidase activity, ! regulation of DNA replication GO:0006275 75 48 2,000 8,589E-04 0,02469453 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 9,595E-04 0,02724463 ! positive regulation of cell growth GO:0030307 16 12 1,000 9,595E-04 0,02691238 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 9,595E-04 0,02658813 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 9,595E-04 0,0262716 ! peptidyl-lysine modification GO:0018205 18 12 1,000 9,595E-04 0,02596253 ! response to gamma radiation GO:0010332 20 12 1,000 9,595E-04 0,02566064 ! positive regulation of cell migration GO:0030335 92 51 2,000 1,026E-03 0,02711416 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,131E-03 0,02956258 ! regulation of cellular pH GO:0030641 20 13 1,000 1,131E-03 0,02923042 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,316E-03 0,03363861 ! cellular response to starvation GO:0009267 21 14 1,000 1,316E-03 0,03326895 ! negative regulation of caspase activity GO:0043154 20 14 1,000 1,316E-03 0,03290733 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 1,316E-03 0,03255349 ! G1/S transition checkpoint GO:0031575 33 14 1,000 1,316E-03 0,03220718 ! positive regulation of cell motion GO:0051272 99 56 2,000 1,346E-03 0,03259711 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 1,417E-03 0,0339554 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 1,417E-03 0,03360534 ! negative regulation of kinase activity GO:0033673 100 58 2,000 1,49E-03 0,03497968 ! positive regulation of cell size GO:0045793 20 15 1,000 1,515E-03 0,03519672 ! skin development GO:0043588 25 15 1,000 1,515E-03 0,03484476 ! lipid phosphorylation GO:0046834 23 15 1,000 1,515E-03 0,03449976 ! regulation of survival gene product expression GO:0045884 20 15 1,000 1,515E-03 0,03416153 ! DNA integration GO:0015074 22 15 1,000 1,515E-03 0,03382986 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 1,515E-03 0,03350457 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 1,515E-03 0,03318548 ! activation of MAPK activity GO:0000187 84 59 2,000 1,566E-03 0,03397792 ! negative regulation of transferase activity GO:0051348 105 61 2,000 1,724E-03 0,03705878 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,727E-03 0,03678028 ! protein amino acid deacetylation GO:0006476 20 16 1,000 1,727E-03 0,03644284 ! protein amino acid acetylation GO:0006473 28 16 1,000 1,727E-03 0,03611154 ! branched chain family amino acid metabolic process GO:0009081 24 16 1,000 1,727E-03 0,03578621 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,727E-03 0,03546669 ! negative regulation of cell growth GO:0030308 106 62 2,000 1,807E-03 0,03677336 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 1,952E-03 0,03939138 ! inactivation of MAPK activity GO:0000188 27 17 1,000 1,952E-03 0,03904884 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 1,952E-03 0,03871222 ! cellular macromolecular complex disassembly GO:0034623 29 17 1,000 1,952E-03 0,03838134 ! cell cycle checkpoint GO:0000075 108 64 2,000 1,979E-03 0,03858018 ! negative regulation of cell size GO:0045792 108 64 2,000 1,979E-03 0,03825598 ! protein oligomerization GO:0051259 100 65 2,000 2,069E-03 0,0396629 ! positive regulation of DNA replication GO:0045740 29 18 1,000 2,191E-03 0,04164694 ! positive regulation of translation GO:0045727 28 18 1,000 2,191E-03 0,04130557 ! somitogenesis GO:0001756 24 18 1,000 2,191E-03 0,04096976 ! cellular response to nutrient levels GO:0031669 27 18 1,000 2,191E-03 0,04063935 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 2,191E-03 0,04031424 ! learning or memory GO:0007611 123 68 2,000 2,355E-03 0,04298169 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 2,443E-03 0,04423639 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 32 19 1,000 2,443E-03 0,04389079 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 2,443E-03 0,04355056 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 2,443E-03 0,04321555 ! apoptotic nuclear changes GO:0030262 24 19 1,000 2,443E-03 0,04288566 ! response to starvation GO:0042594 30 19 1,000 2,443E-03 0,04256077 ! sex determination GO:0007530 29 19 1,000 2,443E-03 0,04224076 ! leukotriene biosynthetic process GO:0019370 26 19 1,000 2,443E-03 0,04192553 GO:0043450|alkene biosynthetic process, ! response to drug GO:0042493 108 69 2,000 2,455E-03 0,04182385 ! lymphocyte differentiation GO:0030098 113 71 2,000 2,663E-03 0,04503904 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 2,707E-03 0,04544968 ! DNA modification GO:0006304 28 20 1,000 2,707E-03 0,04512034 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 2,985E-03 0,04938706 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 2,985E-03 0,0490343 ! protein amino acid acylation GO:0043543 37 21 1,000 2,985E-03 0,04868654 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 2,985E-03 0,04834367 ! cell aging GO:0007569 32 21 1,000 2,985E-03 0,0480056 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 2,985E-03 0,04767223 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 2,985E-03 0,04734346 ! leukotriene metabolic process GO:0006691 28 21 1,000 2,985E-03 0,04701919 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 2,985E-03 0,04669933 ! protein import into nucleus GO:0006606 118 74 2,000 2,996E-03 0,04655279 ! negative regulation of growth GO:0045926 123 75 2,000 3,112E-03 0,04803409 ! nuclear import GO:0051170 121 75 2,000 3,112E-03 0,04771386 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 3,275E-03 0,04988326 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 3,275E-03 0,04955509 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 3,275E-03 0,0492312 ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 3,275E-03 0,04891151 ! macromolecular complex disassembly GO:0032984 38 22 1,000 3,275E-03 0,04859595 ! vasculogenesis GO:0001570 33 22 1,000 3,275E-03 0,04828444 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 3,275E-03 0,0479769 ! cellular alkene metabolic process GO:0043449 29 22 1,000 3,275E-03 0,04767325 ! blastocyst development GO:0001824 37 22 1,000 3,275E-03 0,04737342 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 3,578E-03 0,05143181 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 3,578E-03 0,05111236 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 3,578E-03 0,05079685 ! negative regulation of DNA replication GO:0008156 35 23 1,000 3,578E-03 0,05048521 ! interaction with host GO:0051701 37 23 1,000 3,578E-03 0,05017738 ! cellular response to oxidative stress GO:0034599 33 23 1,000 3,578E-03 0,04987327 ! T cell activation GO:0042110 134 79 2,000 3,604E-03 0,04993726 ! protein localization in nucleus GO:0034504 133 80 2,000 3,734E-03 0,05142996 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 3,893E-03 0,05330192 ! mitochondrial membrane organization GO:0007006 39 24 1,000 3,893E-03 0,05298652 ! negative regulation of cell development GO:0010721 56 24 1,000 3,893E-03 0,05267484 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 3,893E-03 0,0523668 ! iron ion homeostasis GO:0055072 39 25 1,000 4,221E-03 0,05644792 ! regulation of chromosome organization GO:0033044 35 25 1,000 4,221E-03 0,05612163 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 4,428E-03 0,05852664 ! transcription initiation GO:0006352 118 85 2,000 4,428E-03 0,05819221 ! regulation of pH GO:0006885 36 26 1,000 4,562E-03 0,05961261 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 4,562E-03 0,05927582 ! cell cycle arrest GO:0007050 150 86 2,000 4,575E-03 0,05911598 ! response to ionizing radiation GO:0010212 47 27 1,000 4,914E-03 0,06314431 ! leukocyte differentiation GO:0002521 143 90 2,000 5,194E-03 0,06637117 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 5,279E-03 0,06708205 ! icosanoid biosynthetic process GO:0046456 42 28 1,000 5,279E-03 0,06671347 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 5,279E-03 0,06634891 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 5,279E-03 0,06598832 ! positive regulation of catabolic process GO:0009896 40 28 1,000 5,279E-03 0,06563163 ! placenta development GO:0001890 37 28 1,000 5,279E-03 0,06527877 ! in utero embryonic development GO:0001701 147 96 2,000 6,214E-03 0,07642517 ! segmentation GO:0035282 41 31 1,000 6,446E-03 0,07885495 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 1,000 6,446E-03 0,07843773 ! response to mechanical stimulus GO:0009612 43 31 1,000 6,446E-03 0,0780249 ! protein import GO:0017038 156 99 2,000 6,765E-03 0,08146419 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 6,858E-03 0,08215396 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 6,858E-03 0,08172829 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 6,858E-03 0,08130701 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 6,858E-03 0,08089005 ! regulation of translation GO:0006417 151 100 2,000 6,955E-03 0,08161624 ! protein localization in organelle GO:0033365 161 100 2,000 6,955E-03 0,08120195 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 7,282E-03 0,08459239 ! ear morphogenesis GO:0042471 42 33 1,000 7,282E-03 0,0841673 ! carbohydrate homeostasis GO:0033500 39 33 1,000 7,282E-03 0,08374646 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 1,000 7,282E-03 0,08332981 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 7,718E-03 0,08787976 ! neuron migration GO:0001764 46 34 1,000 7,718E-03 0,08744685 ! keratinocyte differentiation GO:0030216 47 35 1,000 8,165E-03 0,09206176 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 8,624E-03 0,09675971 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 1,000 8,624E-03 0,09629 ! cellular amide metabolic process GO:0043603 52 36 1,000 8,624E-03 0,09582484 ! amino acid activation GO:0043038 52 37 1,000 9,094E-03 0,10056214 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 9,094E-03 0,10008098 ! pigmentation GO:0043473 74 38 1,000 9,576E-03 0,10487589 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 0,01006807 0,10974676 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 0,01006807 0,10922909 ! chromatin remodeling GO:0006338 68 39 1,000 0,01006807 0,10871628 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,01057157 0,11361965 ! double-strand break repair GO:0006302 67 40 1,000 0,01057157 0,11309119 ! B cell differentiation GO:0030183 62 40 1,000 0,01057157 0,11256762 ! epidermal cell differentiation GO:0009913 53 40 1,000 0,01057157 0,11204887 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,01057157 0,11153489 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,01108602 0,1164285 ! biopolymer methylation GO:0043414 62 41 1,000 0,01108602 0,11589928 ! mitochondrial transport GO:0006839 60 42 1,000 0,01161133 0,12084194 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,01161133 0,12029761 ! icosanoid metabolic process GO:0006690 61 42 1,000 0,01161133 0,11975816 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,01161133 0,11922353 ! positive regulation of binding GO:0051099 59 43 1,000 0,01214743 0,1241737 ! methylation GO:0032259 64 43 1,000 0,01214743 0,12362426 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,01269421 0,12861972 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,01325158 0,13367827 ! cell redox homeostasis GO:0045454 63 46 1,000 0,01381947 0,1387982 ! unsaturated fatty acid metabolic process GO:0033559 66 46 1,000 0,01381947 0,13819472 ! response to UV GO:0009411 75 46 1,000 0,01381947 0,13759648 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 1,000 0,01439778 0,14273664 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,01439778 0,14212403 ! heart morphogenesis GO:0003007 65 48 1,000 0,01498643 0,1473025 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,01498643 0,14667568 ! RNA elongation GO:0006354 62 49 1,000 0,01558532 0,15189085 ! ear development GO:0043583 72 50 1,000 0,01619438 0,15716063 ! lipid modification GO:0030258 73 50 1,000 0,01619438 0,15650029 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,01619438 0,15584548 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 0,01681351 0,16112948 ! aging GO:0007568 79 52 1,000 0,01744264 0,16646498 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,01744264 0,16577711 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,01808167 0,17114335 ! cell projection assembly GO:0030031 76 53 1,000 0,01808167 0,17044194 ! DNA catabolic process GO:0006308 67 54 1,000 0,01873052 0,17583754 ! detection of external stimulus GO:0009581 66 54 1,000 0,01873052 0,17512275 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01930006 0,17971711 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01930006 0,17899245 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01930006 0,1782736 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01930006 0,17756051 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01930006 0,17685309 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01930006 0,1761513 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01930006 0,17545505 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01930006 0,17476428 ! sleep GO:0030431 11 5 0,000 0,01930006 0,17407893 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01930006 0,17339893 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01930006 0,17272423 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01930006 0,17205476 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01930006 0,17139045 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01930006 0,17073126 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01930006 0,17007711 ! tongue development GO:0043586 6 5 0,000 0,01930006 0,16942797 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01930006 0,16878375 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01930006 0,16814442 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01930006 0,16750991 ! cobalt ion transport GO:0006824 9 5 0,000 0,01930006 0,16688018 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01930006 0,16625516 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01930006 0,1656348 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01930006 0,16501906 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01930006 0,16440788 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01930006 0,16380121 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01930006 0,163199 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01930006 0,1626012 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01930006 0,16200776 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01930006 0,16141864 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01930006 0,16083379 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01930006 0,16025317 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01930006 0,15967672 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01930006 0,1591044 ! malate metabolic process GO:0006108 7 5 0,000 0,01930006 0,15853617 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01930006 0,15797198 ! behavioral response to pain GO:0048266 7 5 0,000 0,01930006 0,1574118 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01930006 0,15685557 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01930006 0,15630326 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01930006 0,15575483 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01930006 0,15521023 ! mating behavior GO:0007617 6 5 0,000 0,01930006 0,15466943 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01930006 0,15413238 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01930006 0,15359905 ! rhythmic behavior GO:0007622 12 5 0,000 0,01930006 0,1530694 ! copulation GO:0007620 7 5 0,000 0,01930006 0,15254339 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01930006 0,15202098 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01930006 0,15150214 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01930006 0,15098683 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01930006 0,15047501 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01930006 0,14996664 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01930006 0,14946171 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01930006 0,14896016 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01930006 0,14846196 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01930006 0,14796709 ! response to protozoan GO:0001562 9 5 0,000 0,01930006 0,1474755 ! lymph vessel development GO:0001945 7 5 0,000 0,01930006 0,14698717 ! endochondral ossification GO:0001958 12 5 0,000 0,01930006 0,14650207 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01930006 0,14602015 ! parathyroid gland development GO:0060017 8 5 0,000 0,01930006 0,1455414 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01930006 0,14506577 ! anagen GO:0042640 6 5 0,000 0,01930006 0,14459325 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01930006 0,14412379 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01930006 0,14365737 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01930006 0,14319396 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01930006 0,14273353 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01930006 0,14227605 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01930006 0,14182149 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01930006 0,14136983 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01930006 0,14092104 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01930006 0,14047508 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01930006 0,14003195 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01930006 0,13959159 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01930006 0,139154 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01930006 0,13871915 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01930006 0,138287 ! ovulation GO:0030728 6 5 0,000 0,01930006 0,13785754 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01930006 0,13743073 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 9 5 0,000 0,01930006 0,13700656 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01930006 0,13658501 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01930006 0,13616603 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01930006 0,13574962 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01930006 0,13533575 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01930006 0,1349244 ! polyol catabolic process GO:0046174 7 5 0,000 0,01930006 0,13451554 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01930006 0,13410914 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01930006 0,1337052 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01930006 0,13330368 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01930006 0,13290457 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01930006 0,13250784 ! urea metabolic process GO:0019627 6 5 0,000 0,01930006 0,13211347 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01930006 0,13172144 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01930006 0,13133174 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01930006 0,13094433 ! neutrophil activation GO:0042119 5 5 0,000 0,01930006 0,1305592 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01930006 0,13017633 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01930006 0,12979569 ! response to food GO:0032094 5 5 0,000 0,01930006 0,12941728 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01930006 0,12904107 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01930006 0,12866703 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01930006 0,12829516 ! forebrain neuron development GO:0021884 7 5 0,000 0,01930006 0,12792544 ! melanosome organization GO:0032438 7 5 0,000 0,01930006 0,12755784 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01930006 0,12719234 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01930006 0,12682893 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01930006 0,1264676 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01930006 0,12610831 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01930006 0,12575107 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01930006 0,12539584 ! nucleoside transport GO:0015858 6 5 0,000 0,01930006 0,12504261 ! nucleoside salvage GO:0043174 7 5 0,000 0,01930006 0,12469137 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01930006 0,12434209 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01930006 0,12399477 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01930006 0,12364938 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01930006 0,12330591 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01930006 0,12296434 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01930006 0,12262466 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01930006 0,12228685 ! depyrimidination GO:0045008 8 5 0,000 0,01930006 0,1219509 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01930006 0,12161679 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01930006 0,1212845 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01930006 0,12095402 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01930006 0,12062534 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01930006 0,12029845 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01930006 0,11997332 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01930006 0,11964994 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01930006 0,1193283 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01930006 0,11900838 ! monocyte differentiation GO:0030224 8 5 0,000 0,01930006 0,11869018 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01930006 0,11837367 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01930006 0,11805885 ! centrosome duplication GO:0051298 5 5 0,000 0,01930006 0,11774569 ! response to UV-C GO:0010225 6 5 0,000 0,01930006 0,1174342 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01930006 0,11712435 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01930006 0,11681612 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01930006 0,11650952 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01930006 0,11620452 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01930006 0,11590111 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01930006 0,11559929 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01930006 0,11529903 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01930006 0,11500033 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01930006 0,11470317 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01930006 0,11440754 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01930006 0,11411344 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01930006 0,11382084 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01930006 0,11352974 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01930006 0,11324012 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01930006 0,11295198 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01930006 0,1126653 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01930006 0,11238007 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01930006 0,11209628 ! neural tube patterning GO:0021532 6 5 0,000 0,01930006 0,11181392 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01930006 0,11153298 ! histone demethylation GO:0016577 9 5 0,000 0,01930006 0,11125345 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01930006 0,11097532 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01930006 0,11069857 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01930006 0,1104232 ! enteric nervous system development GO:0048484 8 5 0,000 0,01930006 0,1101492 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01930006 0,10987655 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01930006 0,10960525 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01930006 0,10933529 ! transcription termination GO:0006353 8 5 0,000 0,01930006 0,10906665 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01930006 0,10879933 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01930006 0,10853332 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01930006 0,1082686 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01930006 0,10800517 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01930006 0,10774303 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01930006 0,10748215 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01930006 0,10722253 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01930006 0,10696416 ! apical protein localization GO:0045176 6 5 0,000 0,01930006 0,10670704 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01930006 0,10645114 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01930006 0,10619648 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01930006 0,10594302 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01930006 0,10569078 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01930006 0,10543973 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01930006 0,10518987 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01930006 0,1049412 ! glial cell migration GO:0008347 10 5 0,000 0,01930006 0,1046937 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01930006 0,10444736 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01930006 0,10420218 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01930006 0,10395814 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01930006 0,10371525 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01930006 0,10347349 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01930006 0,10323285 ! neural plate development GO:0001840 6 5 0,000 0,01930006 0,10299333 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01930006 0,10275492 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01930006 0,10251761 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01930006 0,1022814 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01930006 0,10204627 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01930006 0,10181222 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01930006 0,10157924 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01930006 0,10134732 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01930006 0,10111646 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01930006 0,10088665 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01930006 0,10065788 ! spindle assembly GO:0051225 5 5 0,000 0,01930006 0,10043015 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01930006 0,10020345 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01930006 0,09997776 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01930006 0,09975309 ! organ regeneration GO:0031100 7 5 0,000 0,01930006 0,09952943 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01930006 0,09930677 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01930006 0,0990851 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01930006 0,09886443 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01930006 0,09864473 GO:0055081|anion homeostasis, ! multicellular organism reproduction GO:0032504 83 57 1,000 0,02073518 0,10574484 GO:0048609|reproductive process in a multicellular organism, ! viral reproductive process GO:0022415 87 58 1,000 0,0214225 0,10900827 ! lung development GO:0030324 94 59 1,000 0,02211922 0,11230507 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,02282527 0,11563461 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,02282527 0,11538046 ! tRNA transcription GO:0009304 11 6 0,000 0,02311579 0,1165928 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02311579 0,11633767 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02311579 0,11608366 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02311579 0,11583076 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02311579 0,11557895 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02311579 0,11532824 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02311579 0,11507861 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02311579 0,11483006 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02311579 0,11458258 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02311579 0,11433617 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02311579 0,11409081 ! prostate gland development GO:0030850 9 6 0,000 0,02311579 0,1138465 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02311579 0,11360324 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02311579 0,11336102 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02311579 0,11311982 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02311579 0,11287965 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02311579 0,1126405 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02311579 0,11240236 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02311579 0,11216523 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02311579 0,11192909 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02311579 0,11169394 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02311579 0,11145978 ! neuron adhesion GO:0007158 9 6 0,000 0,02311579 0,1112266 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02311579 0,1109944 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02311579 0,11076316 ! signal peptide processing GO:0006465 8 6 0,000 0,02311579 0,11053288 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02311579 0,11030356 ! mRNA stabilization GO:0048255 15 6 0,000 0,02311579 0,11007519 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02311579 0,10984776 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02311579 0,10962127 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02311579 0,10939571 ! opsonization GO:0008228 8 6 0,000 0,02311579 0,10917108 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02311579 0,10894737 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02311579 0,10872457 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02311579 0,10850269 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02311579 0,1082817 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02311579 0,10806162 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02311579 0,10784243 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02311579 0,10762412 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02311579 0,1074067 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02311579 0,10719015 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02311579 0,10697448 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02311579 0,10675967 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02311579 0,10654572 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02311579 0,10633263 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02311579 0,10612039 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02311579 0,105909 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02311579 0,10569844 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02311579 0,10548872 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02311579 0,10527984 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02311579 0,10507177 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02311579 0,10486453 ! thymic T cell selection GO:0045061 12 6 0,000 0,02311579 0,1046581 ! protein lipoylation GO:0009249 10 6 0,000 0,02311579 0,10445249 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02311579 0,10424768 ! pigment granule organization GO:0048753 11 6 0,000 0,02311579 0,10404367 ! drug transport GO:0015893 6 6 0,000 0,02311579 0,10384046 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02311579 0,10363804 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02311579 0,10343641 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02311579 0,10323557 ! histidine metabolic process GO:0006547 6 6 0,000 0,02311579 0,1030355 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02311579 0,1028362 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02311579 0,10263768 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02311579 0,10243992 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02311579 0,10224292 ! adenohypophysis development GO:0021984 10 6 0,000 0,02311579 0,10204667 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02311579 0,10185118 ! hyperosmotic response GO:0006972 8 6 0,000 0,02311579 0,10165644 ! microtubule nucleation GO:0007020 10 6 0,000 0,02311579 0,10146244 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02311579 0,10126917 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02311579 0,10107665 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02311579 0,10088485 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02311579 0,10069378 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02311579 0,10050343 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02311579 0,10031381 ! response to dietary excess GO:0002021 7 6 0,000 0,02311579 0,10012489 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02311579 0,09993669 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02311579 0,09974919 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02311579 0,09956239 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02311579 0,09937629 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02311579 0,09919089 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02311579 0,09900618 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02311579 0,09882215 ! neuron apoptosis GO:0051402 8 6 0,000 0,02311579 0,09863881 ! organic alcohol transport GO:0015850 9 6 0,000 0,02311579 0,09845614 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02311579 0,09827415 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02311579 0,09809284 ! carnitine transport GO:0015879 8 6 0,000 0,02311579 0,09791219 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02311579 0,0977322 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02311579 0,09755287 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02311579 0,09737421 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02311579 0,09719619 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02311579 0,09701883 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02311579 0,09684211 ! parturition GO:0007567 12 6 0,000 0,02311579 0,09666603 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02311579 0,09649059 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02311579 0,09631579 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02311579 0,09614162 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02311579 0,09596808 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02311579 0,09579517 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02311579 0,09562287 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02311579 0,0954512 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02311579 0,09528014 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02311579 0,09510969 ! macrophage differentiation GO:0030225 10 6 0,000 0,02311579 0,09493985 ! astrocyte development GO:0014002 14 6 0,000 0,02311579 0,09477062 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02311579 0,09460199 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02311579 0,09443396 ! interaction with symbiont GO:0051702 8 6 0,000 0,02311579 0,09426652 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02311579 0,09409968 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02311579 0,09393342 ! eating behavior GO:0042755 6 6 0,000 0,02311579 0,09376775 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02311579 0,09360267 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02311579 0,09343817 ! response to copper ion GO:0046688 9 6 0,000 0,02311579 0,09327424 ! DNA topological change GO:0006265 8 6 0,000 0,02311579 0,09311089 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02311579 0,09294811 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02311579 0,09278589 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02311579 0,09262425 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02311579 0,09246316 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02311579 0,09230263 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02311579 0,09214266 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02311579 0,09198325 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02311579 0,09182438 ! gas homeostasis GO:0033483 11 6 0,000 0,02311579 0,09166606 ! hair follicle maturation GO:0048820 7 6 0,000 0,02311579 0,09150829 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02311579 0,09135106 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02311579 0,09119437 ! Schwann cell development GO:0014044 14 6 0,000 0,02311579 0,09103821 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02311579 0,09088259 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02311579 0,0907275 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02311579 0,09057294 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02311579 0,09041891 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02311579 0,09026539 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02311579 0,0901124 ! histone ubiquitination GO:0016574 7 6 0,000 0,02311579 0,08995993 ! regulation of meiosis GO:0040020 10 6 0,000 0,02311579 0,08980797 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02311579 0,08965652 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02311579 0,08950558 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02311579 0,08935515 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02311579 0,08920523 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02311579 0,08905581 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02311579 0,08890688 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02311579 0,08875846 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02311579 0,08861053 ! receptor internalization GO:0031623 9 6 0,000 0,02311579 0,08846309 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02311579 0,08831614 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02311579 0,08816968 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02311579 0,0880237 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02311579 0,08787821 ! protein deubiquitination GO:0016579 8 6 0,000 0,02311579 0,0877332 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02311579 0,08758866 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02311579 0,0874446 ! axonal fasciculation GO:0007413 9 6 0,000 0,02311579 0,08730101 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02311579 0,0871579 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02311579 0,08701525 ! midbrain development GO:0030901 6 6 0,000 0,02311579 0,08687307 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02311579 0,08673135 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02311579 0,08659009 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02311579 0,0864493 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02311579 0,08630896 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02311579 0,08616907 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02311579 0,08602964 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02311579 0,08589066 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02311579 0,08575212 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02311579 0,08561404 ! adult feeding behavior GO:0008343 6 6 0,000 0,02311579 0,08547639 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02311579 0,08533919 ! blastocyst growth GO:0001832 15 6 0,000 0,02311579 0,08520243 ! pigment granule transport GO:0051904 12 6 0,000 0,02311579 0,08506611 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02311579 0,08493022 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02311579 0,08479476 ! catecholamine transport GO:0051937 7 6 0,000 0,02311579 0,08465974 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02311579 0,08452515 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02311579 0,08439098 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02311579 0,08425724 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02311579 0,08412392 ! protein prenylation GO:0018342 10 6 0,000 0,02311579 0,08399102 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02311579 0,08385854 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,02311579 0,08372648 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02311579 0,08359484 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02311579 0,08346361 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02311579 0,08333278 ! fatty acid biosynthetic process GO:0006633 92 61 1,000 0,02354056 0,08473129 ! respiratory tube development GO:0030323 99 62 1,000 0,02426502 0,08720243 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,02499857 0,08969847 GO:0090046|regulation of transcription regulator activity, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,02499857 0,08955875 ! viral reproduction GO:0016032 92 63 1,000 0,02499857 0,08941947 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,02574113 0,0919326 ! respiratory system development GO:0060541 100 64 1,000 0,02574113 0,09179007 ! B cell activation GO:0042113 104 65 1,000 0,02649261 0,09432355 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,0269169 0,09568603 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0269169 0,09553836 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0269169 0,09539116 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0269169 0,0952444 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0269169 0,0950981 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0269169 0,09495224 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0269169 0,09480683 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0269169 0,09466187 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0269169 0,09451734 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0269169 0,09437326 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0269169 0,09422962 ! reproductive behavior GO:0019098 12 7 0,000 0,0269169 0,09408641 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0269169 0,09394364 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,0269169 0,0938013 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0269169 0,0936594 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,0269169 0,09351792 ! oligopeptide transport GO:0006857 11 7 0,000 0,0269169 0,09337686 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0269169 0,09323624 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0269169 0,09309603 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0269169 0,09295625 ! RNA methylation GO:0001510 11 7 0,000 0,0269169 0,09281688 ! pericardium development GO:0060039 8 7 0,000 0,0269169 0,09267793 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0269169 0,0925394 ! fibril organization GO:0043206 13 7 0,000 0,0269169 0,09240128 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0269169 0,09226358 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0269169 0,09212628 ! lipoprotein transport GO:0042953 9 7 0,000 0,0269169 0,09198939 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0269169 0,09185291 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0269169 0,09171683 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0269169 0,09158115 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0269169 0,09144588 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0269169 0,091311 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0269169 0,09117652 ! chemosensory behavior GO:0007635 9 7 0,000 0,0269169 0,09104244 ! microtubule bundle formation GO:0001578 8 7 0,000 0,0269169 0,09090875 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,0269169 0,09077545 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0269169 0,09064255 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0269169 0,09051003 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0269169 0,0903779 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0269169 0,09024615 ! reflex GO:0060004 12 7 0,000 0,0269169 0,09011479 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0269169 0,08998381 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0269169 0,08985321 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0269169 0,08972299 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0269169 0,08959314 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0269169 0,08946367 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0269169 0,08933457 ! spinal cord patterning GO:0021511 7 7 0,000 0,0269169 0,08920585 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0269169 0,0890775 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0269169 0,08894951 ! adrenal gland development GO:0030325 17 7 0,000 0,0269169 0,08882189 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0269169 0,08869464 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0269169 0,08856775 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0269169 0,08844123 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0269169 0,08831506 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0269169 0,08818926 ! endosome organization GO:0007032 10 7 0,000 0,0269169 0,08806381 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0269169 0,08793872 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0269169 0,08781399 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0269169 0,0876896 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,0269169 0,08756557 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0269169 0,08744189 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0269169 0,08731856 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0269169 0,08719558 ! galactose metabolic process GO:0006012 10 7 0,000 0,0269169 0,08707294 ! vesicle fusion GO:0006906 15 7 0,000 0,0269169 0,08695065 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0269169 0,0868287 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,0269169 0,08670709 ! organ growth GO:0035265 11 7 0,000 0,0269169 0,08658582 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0269169 0,08646489 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,0269169 0,0863443 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0269169 0,08622404 ! retinol metabolic process GO:0042572 9 7 0,000 0,0269169 0,08610412 ! behavioral fear response GO:0001662 13 7 0,000 0,0269169 0,08598453 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0269169 0,08586527 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0269169 0,08574634 ! rRNA modification GO:0000154 12 7 0,000 0,0269169 0,08562775 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0269169 0,08550948 ! response to UV-B GO:0010224 11 7 0,000 0,0269169 0,08539153 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0269169 0,08527391 ! intermediate filament organization GO:0045109 11 7 0,000 0,0269169 0,08515662 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0269169 0,08503964 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0269169 0,08492299 ! fibrinolysis GO:0042730 9 7 0,000 0,0269169 0,08480666 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,0269169 0,08469064 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0269169 0,08457495 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0269169 0,08445956 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0269169 0,0843445 ! response to tropane GO:0014073 13 7 0,000 0,0269169 0,08422974 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0269169 0,0841153 ! melanosome localization GO:0032400 10 7 0,000 0,0269169 0,08400117 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0269169 0,08388734 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0269169 0,08377383 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0269169 0,08366062 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0269169 0,08354772 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0269169 0,08343512 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0269169 0,08332283 ! mast cell activation GO:0045576 9 7 0,000 0,0269169 0,08321083 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0269169 0,08309914 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0269169 0,08298775 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0269169 0,08287665 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0269169 0,08276586 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0269169 0,08265535 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0269169 0,08254515 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,0269169 0,08243523 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0269169 0,08232561 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0269169 0,08221628 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0269169 0,08210724 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0269169 0,08199849 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0269169 0,08189003 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0269169 0,08178185 ! neuroblast proliferation GO:0007405 13 7 0,000 0,0269169 0,08167396 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0269169 0,08156635 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0269169 0,08145903 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,0269169 0,08135198 ! diuresis GO:0030146 12 7 0,000 0,0269169 0,08124522 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0269169 0,08113874 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0269169 0,08103254 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0269169 0,08092661 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0269169 0,08082097 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0269169 0,08071559 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0269169 0,0806105 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0269169 0,08050567 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0269169 0,08040112 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0269169 0,08029684 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0269169 0,08019282 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,0269169 0,08008908 ! lymph node development GO:0048535 9 7 0,000 0,0269169 0,07998561 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0269169 0,0798824 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0269169 0,07977946 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0269169 0,07967678 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0269169 0,07957437 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0269169 0,07947222 ! ATP catabolic process GO:0006200 10 7 0,000 0,0269169 0,07937033 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0269169 0,07926871 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0269169 0,07916734 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0269169 0,07906623 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0269169 0,07896538 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0269169 0,07886479 ! muscle adaptation GO:0043500 12 7 0,000 0,0269169 0,07876445 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0269169 0,07866437 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0269169 0,07856454 ! retina homeostasis GO:0001895 9 7 0,000 0,0269169 0,07846497 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0269169 0,07836565 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0269169 0,07826657 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0269169 0,07816775 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0269169 0,07806918 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0269169 0,07797086 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0269169 0,07787278 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0269169 0,07777495 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,02879985 0,08311125 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,02958627 0,08527371 ! eye development GO:0001654 111 70 1,000 0,03038123 0,08745535 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,03038123 0,08734603 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 1,000 0,03038123 0,08723699 ! regulation of catabolic process GO:0009894 106 70 1,000 0,03038123 0,08712821 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03070343 0,08794257 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03070343 0,08783319 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,03070343 0,08772408 ! axon extension GO:0048675 11 8 0,000 0,03070343 0,08761524 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,03070343 0,08750667 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03070343 0,08739837 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03070343 0,08729034 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03070343 0,08718257 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03070343 0,08707507 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03070343 0,08696784 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,03070343 0,08686087 ! phosphate transport GO:0006817 10 8 0,000 0,03070343 0,08675416 ! N-glycan processing GO:0006491 12 8 0,000 0,03070343 0,08664771 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03070343 0,08654153 ! UTP metabolic process GO:0046051 8 8 0,000 0,03070343 0,0864356 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03070343 0,08632993 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03070343 0,08622452 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,03070343 0,08611937 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03070343 0,08601448 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,03070343 0,08590984 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03070343 0,08580545 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03070343 0,08570132 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03070343 0,08559744 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03070343 0,08549381 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03070343 0,08539043 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03070343 0,0852873 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03070343 0,08518442 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,03070343 0,08508179 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03070343 0,0849794 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03070343 0,08487726 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03070343 0,08477537 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03070343 0,08467372 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,03070343 0,08457232 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03070343 0,08447115 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03070343 0,08437023 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03070343 0,08426955 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03070343 0,08416911 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,03070343 0,08406891 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03070343 0,08396895 ! melanin metabolic process GO:0006582 12 8 0,000 0,03070343 0,08386922 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03070343 0,08376973 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03070343 0,08367048 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,03070343 0,08357146 ! macrophage activation GO:0042116 12 8 0,000 0,03070343 0,08347268 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03070343 0,08337413 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03070343 0,08327581 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03070343 0,08317772 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03070343 0,08307986 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03070343 0,08298224 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,03070343 0,08288484 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03070343 0,08278767 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03070343 0,08269073 ! ruffle organization GO:0031529 11 8 0,000 0,03070343 0,08259402 ! osteoblast development GO:0002076 13 8 0,000 0,03070343 0,08249753 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,03070343 0,08240127 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03070343 0,08230523 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03070343 0,08220941 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03070343 0,08211382 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,03070343 0,08201845 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03070343 0,0819233 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03070343 0,08182837 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03070343 0,08173366 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03070343 0,08163917 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,03070343 0,0815449 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,03070343 0,08145085 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03070343 0,08135701 ! segment specification GO:0007379 10 8 0,000 0,03070343 0,08126339 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,03070343 0,08116998 ! cellular extravasation GO:0045123 11 8 0,000 0,03070343 0,08107679 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03070343 0,08098381 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,03070343 0,08089105 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03070343 0,08079849 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,03070343 0,08070615 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03070343 0,08061402 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03070343 0,0805221 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03070343 0,08043039 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03070343 0,08033889 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03070343 0,0802476 ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03070343 0,08015651 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03070343 0,08006563 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03070343 0,07997495 ! icosanoid secretion GO:0032309 12 8 0,000 0,03070343 0,07988448 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,03070343 0,07979422 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03070343 0,07970416 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03070343 0,0796143 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03070343 0,07952464 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03070343 0,07943519 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03070343 0,07934594 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03070343 0,07925688 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,03070343 0,07916803 ! sterol catabolic process GO:0016127 9 8 0,000 0,03070343 0,07907938 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03070343 0,07899092 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03070343 0,07890266 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03070343 0,0788146 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03070343 0,07872674 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03070343 0,07863907 ! prophase GO:0051324 11 8 0,000 0,03070343 0,0785516 ! S phase GO:0051320 8 8 0,000 0,03070343 0,07846432 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03070343 0,07837723 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,03070343 0,07829034 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03070343 0,07820364 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03070343 0,07811713 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03070343 0,07803081 ! hormone catabolic process GO:0042447 13 8 0,000 0,03070343 0,07794468 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03070343 0,07785875 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03070343 0,077773 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03070343 0,07768744 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03070343 0,07760207 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03070343 0,07751689 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03070343 0,07743189 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03070343 0,07734708 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03070343 0,07726246 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03070343 0,07717802 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03070343 0,07709376 ! lamellipodium assembly GO:0030032 9 8 0,000 0,03070343 0,07700969 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03070343 0,0769258 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,03070343 0,07684209 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,03070343 0,07675857 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,03199646 0,0799043 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 0,03199646 0,07981764 ! response to oxygen levels GO:0070482 137 74 1,000 0,03364495 0,08383898 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03447544 0,08581549 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03447544 0,08572272 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,03447544 0,08563015 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03447544 0,08553777 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03447544 0,0854456 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03447544 0,08535362 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03447544 0,08526185 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03447544 0,08517026 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03447544 0,08507888 ! GTP metabolic process GO:0046039 9 9 0,000 0,03447544 0,08498769 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03447544 0,0848967 ! social behavior GO:0035176 14 9 0,000 0,03447544 0,0848059 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03447544 0,08471529 ! artery development GO:0060840 19 9 0,000 0,03447544 0,08462488 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03447544 0,08453467 ! response to pain GO:0048265 16 9 0,000 0,03447544 0,08444464 ! protein complex disassembly GO:0043241 17 9 0,000 0,03447544 0,0843548 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03447544 0,08426516 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03447544 0,08417571 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03447544 0,08408644 ! lung alveolus development GO:0048286 17 9 0,000 0,03447544 0,08399737 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03447544 0,08390848 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,03447544 0,08381978 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03447544 0,08373127 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03447544 0,08364295 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03447544 0,08355481 ! protein targeting to ER GO:0045047 19 9 0,000 0,03447544 0,08346686 ! T cell selection GO:0045058 18 9 0,000 0,03447544 0,08337909 ! endoderm development GO:0007492 12 9 0,000 0,03447544 0,08329151 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03447544 0,08320411 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03447544 0,08311689 ! arginine catabolic process GO:0006527 10 9 0,000 0,03447544 0,08302986 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03447544 0,08294301 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03447544 0,08285634 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03447544 0,08276985 ! V(D)J recombination GO:0033151 12 9 0,000 0,03447544 0,08268354 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03447544 0,08259741 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03447544 0,08251146 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03447544 0,08242569 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03447544 0,0823401 ! mannose metabolic process GO:0006013 9 9 0,000 0,03447544 0,08225468 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03447544 0,08216945 ! receptor clustering GO:0043113 15 9 0,000 0,03447544 0,08208438 ! epithelial cell development GO:0002064 10 9 0,000 0,03447544 0,0819995 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03447544 0,08191479 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03447544 0,08183025 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03447544 0,08174589 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03447544 0,08166171 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03447544 0,08157769 ! motor axon guidance GO:0008045 14 9 0,000 0,03447544 0,08149385 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03447544 0,08141018 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03447544 0,08132668 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03447544 0,08124336 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03447544 0,0811602 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03447544 0,08107721 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03447544 0,0809944 ! DNA ligation GO:0006266 14 9 0,000 0,03447544 0,08091175 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03447544 0,08082927 ! response to amine stimulus GO:0014075 13 9 0,000 0,03447544 0,08074696 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03447544 0,08066482 ! erythrocyte development GO:0048821 11 9 0,000 0,03447544 0,08058284 ! renal water homeostasis GO:0003091 14 9 0,000 0,03447544 0,08050103 ! postreplication repair GO:0006301 11 9 0,000 0,03447544 0,08041939 ! mRNA cleavage GO:0006379 13 9 0,000 0,03447544 0,08033791 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03447544 0,0802566 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03447544 0,08017545 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03447544 0,08009446 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03447544 0,08001364 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03447544 0,07993298 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03447544 0,07985248 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03447544 0,07977215 ! acid secretion GO:0046717 14 9 0,000 0,03447544 0,07969198 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03447544 0,07961196 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03447544 0,07953211 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03447544 0,07945242 ! purine base metabolic process GO:0006144 18 9 0,000 0,03447544 0,07937289 ! oocyte differentiation GO:0009994 12 9 0,000 0,03447544 0,07929352 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03447544 0,0792143 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03447544 0,07913525 ! spleen development GO:0048536 15 9 0,000 0,03447544 0,07905635 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03447544 0,07897761 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03447544 0,07889902 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03447544 0,07882059 ! detection of calcium ion GO:0005513 13 9 0,000 0,03447544 0,07874232 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03447544 0,0786642 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03447544 0,07858624 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03447544 0,07850843 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03447544 0,07843078 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03447544 0,07835328 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03447544 0,07827593 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03447544 0,07819873 ! prepulse inhibition GO:0060134 14 9 0,000 0,03447544 0,07812169 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,03447544 0,0780448 ! insulin secretion GO:0030073 17 9 0,000 0,03447544 0,07796806 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03447544 0,07789147 ! response to nicotine GO:0035094 16 9 0,000 0,03447544 0,07781503 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03447544 0,07773874 ! nucleus localization GO:0051647 15 9 0,000 0,03447544 0,0776626 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03447544 0,07758661 ! localization within membrane GO:0051668 15 9 0,000 0,03447544 0,07751077 ! tRNA metabolic process GO:0006399 95 76 1,000 0,03532609 0,0793457 ! regulation of DNA binding GO:0051101 119 77 1,000 0,03617872 0,08118151 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,03617872 0,08110239 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,03703929 0,0829507 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03823299 0,08554074 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03823299 0,08545761 ! neuron fate specification GO:0048665 11 10 0,000 0,03823299 0,08537464 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03823299 0,08529183 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03823299 0,08520919 ! thyroid gland development GO:0030878 19 10 0,000 0,03823299 0,0851267 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,03823299 0,08504437 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03823299 0,0849622 ! synapsis GO:0007129 13 10 0,000 0,03823299 0,08488019 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03823299 0,08479834 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03823299 0,08471665 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03823299 0,08463511 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03823299 0,08455373 ! sulfate transport GO:0008272 12 10 0,000 0,03823299 0,08447251 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03823299 0,08439144 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03823299 0,08431053 ! androgen metabolic process GO:0008209 13 10 0,000 0,03823299 0,08422977 ! phospholipid efflux GO:0033700 16 10 0,000 0,03823299 0,08414917 ! hippocampus development GO:0021766 19 10 0,000 0,03823299 0,08406872 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,03823299 0,08398842 ! blood vessel remodeling GO:0001974 21 10 0,000 0,03823299 0,08390828 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03823299 0,08382829 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03823299 0,08374846 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03823299 0,08366877 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03823299 0,08358924 ! pathogenesis GO:0009405 13 10 0,000 0,03823299 0,08350986 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03823299 0,08343063 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03823299 0,08335155 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03823299 0,08327261 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03823299 0,08319383 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,03823299 0,0831152 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03823299 0,08303671 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03823299 0,08295838 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03823299 0,08288019 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03823299 0,08280215 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03823299 0,08272425 ! B cell proliferation GO:0042100 14 10 0,000 0,03823299 0,0826465 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03823299 0,0825689 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03823299 0,08249145 ! forebrain cell migration GO:0021885 17 10 0,000 0,03823299 0,08241413 ! lipid digestion GO:0044241 15 10 0,000 0,03823299 0,08233697 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03823299 0,08225994 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03823299 0,08218307 ! UV protection GO:0009650 14 10 0,000 0,03823299 0,08210633 ! entry into host cell GO:0030260 20 10 0,000 0,03823299 0,08202974 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03823299 0,08195329 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03823299 0,08187698 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03823299 0,08180082 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03823299 0,0817248 ! regulation of bone resorption GO:0045124 24 10 0,000 0,03823299 0,08164891 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03823299 0,08157317 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03823299 0,08149757 ! regulation of organ growth GO:0046620 11 10 0,000 0,03823299 0,08142211 ! response to dsRNA GO:0043331 18 10 0,000 0,03823299 0,08134679 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03823299 0,08127161 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03823299 0,08119657 ! embryonic axis specification GO:0000578 12 10 0,000 0,03823299 0,08112166 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03823299 0,08104689 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03823299 0,08097227 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03823299 0,08089777 ! cranial nerve development GO:0021545 12 10 0,000 0,03823299 0,08082342 ! fucose catabolic process GO:0019317 16 10 0,000 0,03823299 0,0807492 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03823299 0,08067512 ! protein sumoylation GO:0016925 12 10 0,000 0,03823299 0,08060117 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03823299 0,08052736 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03823299 0,08045369 ! zymogen activation GO:0031638 14 10 0,000 0,03823299 0,08038015 ! salivary gland development GO:0007431 22 10 0,000 0,03823299 0,08030674 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03823299 0,08023347 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03823299 0,08016033 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03823299 0,08008732 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03823299 0,08001445 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,03823299 0,07994171 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03823299 0,0798691 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03823299 0,07979662 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03823299 0,07972428 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03823299 0,07965207 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03823299 0,07957998 ! detection of bacterium GO:0016045 10 10 0,000 0,03823299 0,07950803 ! embryonic gut development GO:0048566 11 10 0,000 0,03823299 0,07943621 ! activation of innate immune response GO:0002218 10 10 0,000 0,03823299 0,07936451 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03823299 0,07929295 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03823299 0,07922151 ! developmental induction GO:0031128 13 10 0,000 0,03823299 0,07915021 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03823299 0,07907903 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,03823299 0,07900798 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03823299 0,07893706 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03823299 0,07886626 ! forebrain development GO:0030900 131 80 1,000 0,03878398 0,07993114 ! mRNA transport GO:0051028 121 81 1,000 0,03966795 0,08167975 ! detection of stimulus GO:0051606 108 82 1,000 0,04055957 0,08344098 ! rRNA transcription GO:0009303 17 11 0,000 0,04197613 0,08627802 ! respiratory burst GO:0045730 14 11 0,000 0,04197613 0,08620099 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,04197613 0,08612409 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,04197613 0,08604733 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,04197613 0,08597071 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,04197613 0,08589422 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,04197613 0,08581787 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,04197613 0,08574166 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,04197613 0,08566558 ! RNA polyadenylation GO:0043631 19 11 0,000 0,04197613 0,08558963 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,04197613 0,08551382 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,04197613 0,08543815 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,04197613 0,0853626 ! T cell proliferation GO:0042098 20 11 0,000 0,04197613 0,08528719 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,04197613 0,08521192 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,04197613 0,08513678 ! bone resorption GO:0045453 16 11 0,000 0,04197613 0,08506177 ! regulated secretory pathway GO:0045055 14 11 0,000 0,04197613 0,08498689 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,04197613 0,08491214 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,04197613 0,08483753 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,04197613 0,08476304 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,04197613 0,08468869 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,04197613 0,08461447 ! syncytium formation GO:0006949 15 11 0,000 0,04197613 0,08454037 ! plasma membrane organization GO:0007009 18 11 0,000 0,04197613 0,08446641 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,04197613 0,08439257 ! focal adhesion formation GO:0048041 24 11 0,000 0,04197613 0,08431887 ! mitotic spindle organization GO:0007052 15 11 0,000 0,04197613 0,08424529 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,04197613 0,08417184 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,04197613 0,08409852 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,04197613 0,08402533 ! adult heart development GO:0007512 11 11 0,000 0,04197613 0,08395226 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,04197613 0,08387933 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,04197613 0,08380651 ! temperature homeostasis GO:0001659 16 11 0,000 0,04197613 0,08373383 ! L-glutamate transport GO:0015813 16 11 0,000 0,04197613 0,08366127 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,04197613 0,08358884 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,04197613 0,08351653 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,04197613 0,08344434 ! stem cell development GO:0048864 29 11 0,000 0,04197613 0,08337228 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,04197613 0,08330035 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,04197613 0,08322854 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,04197613 0,08315685 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,04197613 0,08308529 ! vasoconstriction GO:0042310 15 11 0,000 0,04197613 0,08301385 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,04197613 0,08294253 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,04197613 0,08287133 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,04197613 0,08280026 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,04197613 0,08272931 ! ribosome assembly GO:0042255 13 11 0,000 0,04197613 0,08265848 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,04197613 0,08258777 GO:0006809|nitric oxide biosynthetic process, ! chromatin silencing GO:0006342 19 11 0,000 0,04197613 0,08251718 ! nucleosome positioning GO:0016584 13 11 0,000 0,04197613 0,08244672 ! T cell homeostasis GO:0043029 20 11 0,000 0,04197613 0,08237637 ! regulation of isotype switching GO:0045191 19 11 0,000 0,04197613 0,08230614 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,04197613 0,08223603 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,04197613 0,08216605 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,04197613 0,08209618 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,04197613 0,08202643 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,04197613 0,0819568 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,04197613 0,08188728 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,04197613 0,08181789 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,04197613 0,08174861 ! male genitalia development GO:0030539 13 11 0,000 0,04197613 0,08167945 ! cholesterol efflux GO:0033344 19 11 0,000 0,04197613 0,0816104 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,04197613 0,08154147 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,04197613 0,08147266 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,04197613 0,08140397 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,04197613 0,08133539 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,04197613 0,08126692 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,04197613 0,08119857 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,04197613 0,08113034 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,04197613 0,08106222 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,04197613 0,08099422 ! lysogeny GO:0030069 18 11 0,000 0,04197613 0,08092632 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,04197613 0,08085855 ! acrosome reaction GO:0007340 13 11 0,000 0,04197613 0,08079088 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,04197613 0,08072333 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,04327967 0,0831606 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,04513005 0,08664366 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 1,000 0,04513005 0,0865714 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,04513005 0,08649926 ! lactation GO:0007595 20 12 0,000 0,04570492 0,08752815 ! reproductive cellular process GO:0048610 14 12 0,000 0,04570492 0,08745534 ! tRNA modification GO:0006400 14 12 0,000 0,04570492 0,08738264 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,04570492 0,08731006 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,04570492 0,0872376 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,04570492 0,08716527 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,04570492 0,08709305 ! non-recombinational repair GO:0000726 19 12 0,000 0,04570492 0,08702095 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,04570492 0,08694898 ! peroxisomal transport GO:0043574 21 12 0,000 0,04570492 0,08687712 ! cartilage condensation GO:0001502 18 12 0,000 0,04570492 0,08680538 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,04570492 0,08673376 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,04570492 0,08666225 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,04570492 0,08659087 ! heart looping GO:0001947 15 12 0,000 0,04570492 0,0865196 ! palate development GO:0060021 15 12 0,000 0,04570492 0,08644845 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,04570492 0,08637741 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,04570492 0,0863065 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,04570492 0,0862357 ! arginine metabolic process GO:0006525 13 12 0,000 0,04570492 0,08616501 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,04570492 0,08609444 ! methionine metabolic process GO:0006555 13 12 0,000 0,04570492 0,08602399 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,04570492 0,08595365 ! Golgi organization GO:0007030 18 12 0,000 0,04570492 0,08588343 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,04570492 0,08581332 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,04570492 0,08574332 ! monoamine transport GO:0015844 13 12 0,000 0,04570492 0,08567344 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04570492 0,08560367 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,04570492 0,08553402 ! L-amino acid transport GO:0015807 20 12 0,000 0,04570492 0,08546448 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,04570492 0,08539506 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,04570492 0,08532574 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,04570492 0,08525654 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04570492 0,08518745 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,04570492 0,08511847 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,04570492 0,08504961 ! cerebellum development GO:0021549 13 12 0,000 0,04570492 0,08498085 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,04570492 0,08491221 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,04570492 0,08484367 ! histone methylation GO:0016571 15 12 0,000 0,04570492 0,08477525 ! autonomic nervous system development GO:0048483 23 12 0,000 0,04570492 0,08470694 ! gland morphogenesis GO:0022612 23 12 0,000 0,04570492 0,08463874 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,04570492 0,08457065 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,04570492 0,08450266 ! regulation of epidermis development GO:0045682 17 12 0,000 0,04570492 0,08443479 ! intestinal absorption GO:0050892 19 12 0,000 0,04570492 0,08436702 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,04570492 0,08429937 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,04570492 0,08423182 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,04570492 0,08416438 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,04570492 0,08409705 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,04570492 0,08402983 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,04570492 0,08396271 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,04570492 0,0838957 ! microspike assembly GO:0030035 23 12 0,000 0,04570492 0,0838288 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,04570492 0,083762 ! response to cold GO:0009409 14 12 0,000 0,04570492 0,08369531 ! establishment of RNA localization GO:0051236 128 88 1,000 0,04606612 0,08428965 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 1,000 0,04606612 0,08422265 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,04700937 0,08587891 ! reproductive developmental process GO:0003006 127 89 1,000 0,04700937 0,08581075 ! RNA localization GO:0006403 135 91 1,000 0,04891709 0,08922228 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,0494194 0,09006706 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,0494194 0,08999575 ! cGMP metabolic process GO:0046068 16 13 0,000 0,0494194 0,08992455 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,0494194 0,08985346 ! water transport GO:0006833 17 13 0,000 0,0494194 0,08978249 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,0494194 0,08971163 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,0494194 0,08964088 ! lipid localization GO:0010876 24 13 0,000 0,0494194 0,08957024 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,0494194 0,08949971 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,0494194 0,08942929 ! organelle fusion GO:0048284 28 13 0,000 0,0494194 0,08935899 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,0494194 0,08928879 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,0494194 0,0892187 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,0494194 0,08914873 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,0494194 0,08907886 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,0494194 0,08900911 ! response to hexose stimulus GO:0009746 19 13 0,000 0,0494194 0,08893946 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,0494194 0,08886992 ! glutamate metabolic process GO:0006536 18 13 0,000 0,0494194 0,08880049 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,0494194 0,08873117 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,0494194 0,08866196 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,0494194 0,08859285 ! NAD metabolic process GO:0019674 21 13 0,000 0,0494194 0,08852386 ! exocrine system development GO:0035272 27 13 0,000 0,0494194 0,08845496 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,0494194 0,08838618 ! bone mineralization GO:0030282 15 13 0,000 0,0494194 0,08831751 ! regulation of exocytosis GO:0017157 17 13 0,000 0,0494194 0,08824894 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,0494194 0,08818047 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,0494194 0,08811212 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,0494194 0,08804387 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,0494194 0,08797572 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,0494194 0,08790768 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,0494194 0,08783974 ! genitalia development GO:0048806 15 13 0,000 0,0494194 0,08777192 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,0494194 0,08770419 ! cellular pigmentation GO:0033059 24 13 0,000 0,0494194 0,08763657 ! tissue regeneration GO:0042246 21 13 0,000 0,0494194 0,08756905 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,0494194 0,08750164 ! cofactor transport GO:0051181 19 13 0,000 0,0494194 0,08743433 ! NADP metabolic process GO:0006739 18 13 0,000 0,0494194 0,08736713 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,0494194 0,08730002 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,0494194 0,08723302 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0494194 0,08716613 ! gas transport GO:0015669 18 13 0,000 0,0494194 0,08709933 ! regulation of RNA stability GO:0043487 28 13 0,000 0,0494194 0,08703264 ! heme biosynthetic process GO:0006783 20 13 0,000 0,0494194 0,08696605 ! regulation of axon extension GO:0030516 23 13 0,000 0,0494194 0,08689956 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,0494194 0,08683318 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,0494194 0,08676689 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,0494194 0,08670071 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,0494194 0,08663463 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,0494194 0,08656864 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,0494194 0,08650276 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,04988143 0,08724508 ! cell fate commitment GO:0045165 141 92 1,000 0,04988143 0,08717878 ! sulfur metabolic process GO:0006790 118 92 1,000 0,04988143 0,08711259 ! response to oxidative stress GO:0006979 141 94 1,000 0,05183073 0,09044816 ! regulation of binding GO:0051098 151 95 1,000 0,05281556 0,09209688 ! angiogenesis GO:0001525 149 95 1,000 0,05281556 0,09202711 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,05311964 0,09248689 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,05311964 0,09241693 ! superoxide anion generation GO:0042554 18 14 0,000 0,05311964 0,09234708 ! neuron maturation GO:0042551 21 14 0,000 0,05311964 0,09227733 ! regulation of S phase GO:0033261 18 14 0,000 0,05311964 0,09220768 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,05311964 0,09213815 ! myotube differentiation GO:0014902 21 14 0,000 0,05311964 0,09206871 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,05311964 0,09199938 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,05311964 0,09193016 ! inositol metabolic process GO:0006020 20 14 0,000 0,05311964 0,09186104 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,05311964 0,09179202 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,05311964 0,09172311 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,05311964 0,0916543 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,05311964 0,09158559 ! gene silencing by RNA GO:0031047 20 14 0,000 0,05311964 0,09151699 ! response to cAMP GO:0051591 19 14 0,000 0,05311964 0,09144849 ! limbic system development GO:0021761 25 14 0,000 0,05311964 0,09138009 ! startle response GO:0001964 21 14 0,000 0,05311964 0,09131179 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,05311964 0,0912436 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,05311964 0,09117551 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,05311964 0,09110752 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,05311964 0,09103963 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,05311964 0,09097184 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,05311964 0,09090415 ! glycine metabolic process GO:0006544 22 14 0,000 0,05311964 0,09083657 ! pituitary gland development GO:0021983 23 14 0,000 0,05311964 0,09076908 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,05311964 0,09070169 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,05311964 0,09063441 ! regulation of heart rate GO:0002027 23 14 0,000 0,05311964 0,09056722 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,05311964 0,09050013 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,05311964 0,09043315 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,05311964 0,09036626 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,05311964 0,09029947 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,05311964 0,09023278 ! axon cargo transport GO:0008088 27 14 0,000 0,05311964 0,09016618 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,05311964 0,09009969 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,05311964 0,09003329 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,05311964 0,089967 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,05311964 0,08990079 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05311964 0,08983469 ! mRNA splice site selection GO:0006376 26 14 0,000 0,05311964 0,08976869 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,05311964 0,08970278 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,05311964 0,08963696 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,05311964 0,08957125 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,05311964 0,08950563 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,05311964 0,0894401 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,05311964 0,08937467 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,05311964 0,08930934 ! muscle maintenance GO:0046716 19 14 0,000 0,05311964 0,08924411 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,05311964 0,08917896 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,05311964 0,08911392 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,05311964 0,08904897 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,05311964 0,08898411 ! cell killing GO:0001906 20 14 0,000 0,05311964 0,08891935 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,05311964 0,08885468 ! cilium assembly GO:0042384 20 14 0,000 0,05311964 0,0887901 ! peptide hormone secretion GO:0030072 23 14 0,000 0,05311964 0,08872562 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,05380709 0,08980863 ! protein maturation GO:0051604 129 96 1,000 0,05380709 0,08974351 ! response to light stimulus GO:0009416 153 96 1,000 0,05380709 0,08967848 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,05680569 0,09460759 ! metencephalon development GO:0022037 19 15 0,000 0,05680569 0,09453914 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05680569 0,09447078 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,05680569 0,09440252 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,05680569 0,09433436 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,05680569 0,0942663 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,05680569 0,09419833 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,05680569 0,09413047 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05680569 0,0940627 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05680569 0,09399503 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05680569 0,09392745 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,05680569 0,09385998 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05680569 0,0937926 ! adult walking behavior GO:0007628 25 15 0,000 0,05680569 0,09372531 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05680569 0,09365813 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,05680569 0,09359104 ! myoblast differentiation GO:0045445 27 15 0,000 0,05680569 0,09352404 ! centrosome cycle GO:0007098 16 15 0,000 0,05680569 0,09345714 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05680569 0,09339034 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,05680569 0,09332363 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,05680569 0,09325702 ! cerebral cortex development GO:0021987 29 15 0,000 0,05680569 0,0931905 ! response to osmotic stress GO:0006970 22 15 0,000 0,05680569 0,09312408 ! vesicle coating GO:0006901 25 15 0,000 0,05680569 0,09305775 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,05680569 0,09299152 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,05680569 0,09292538 ! peptide secretion GO:0002790 27 15 0,000 0,05680569 0,09285934 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05680569 0,09279339 ! regulation of vasodilation GO:0042312 24 15 0,000 0,05680569 0,09272753 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,05680569 0,09266176 ! neuron recognition GO:0008038 22 15 0,000 0,05680569 0,09259609 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05680569 0,09253052 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,05680569 0,09246503 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,05680569 0,09239964 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05680569 0,09233434 ! biomineral formation GO:0031214 18 15 0,000 0,05680569 0,09226913 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05680569 0,09220401 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,05680569 0,09213899 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05680569 0,09207406 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05680569 0,09200922 ! organic cation transport GO:0015695 19 15 0,000 0,05680569 0,09194447 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05680569 0,09187981 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05680569 0,09181524 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,05680569 0,09175076 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 27 15 0,000 0,05680569 0,09168638 ! peptide hormone processing GO:0016486 19 15 0,000 0,05680569 0,09162208 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,05680569 0,09155788 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,05783889 0,09315787 ! protein secretion GO:0009306 27 16 0,000 0,0604776 0,09733973 ! hormone secretion GO:0046879 25 16 0,000 0,0604776 0,09727166 ! bone remodeling GO:0046849 24 16 0,000 0,0604776 0,09720369 ! endothelial cell migration GO:0043542 22 16 0,000 0,0604776 0,09713581 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,0604776 0,09706802 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,0604776 0,09700033 ! glial cell development GO:0021782 24 16 0,000 0,0604776 0,09693274 ! patterning of blood vessels GO:0001569 24 16 0,000 0,0604776 0,09686523 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,0604776 0,09679783 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,0604776 0,09673051 ! protein polyubiquitination GO:0000209 26 16 0,000 0,0604776 0,09666329 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,0604776 0,09659616 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,0604776 0,09652913 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,0604776 0,09646219 ! fructose metabolic process GO:0006000 20 16 0,000 0,0604776 0,09639534 ! regulation of protein binding GO:0043393 27 16 0,000 0,0604776 0,09632858 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,0604776 0,09626192 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,0604776 0,09619535 ! protein export from nucleus GO:0006611 24 16 0,000 0,0604776 0,09612887 ! negative regulation of immune response GO:0050777 28 16 0,000 0,0604776 0,09606248 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,0604776 0,09599619 ! DNA replication initiation GO:0006270 25 16 0,000 0,0604776 0,09592998 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,0604776 0,09586387 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,0604776 0,09579785 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,0604776 0,09573192 ! diencephalon development GO:0021536 25 16 0,000 0,0604776 0,09566608 ! oogenesis GO:0048477 23 16 0,000 0,0604776 0,09560033 ! neural crest cell migration GO:0001755 24 16 0,000 0,0604776 0,09553467 ! G1 phase GO:0051318 27 16 0,000 0,0604776 0,0954691 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,0604776 0,09540362 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,0604776 0,09533823 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,0604776 0,09527293 ! steroid catabolic process GO:0006706 22 16 0,000 0,0604776 0,09520772 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,0604776 0,0951426 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,0604776 0,09507756 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,0604776 0,09501262 ! sperm-egg recognition GO:0035036 16 16 0,000 0,0604776 0,09494777 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,0604776 0,094883 ! nerve development GO:0021675 18 16 0,000 0,0604776 0,09481832 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,0604776 0,09475373 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,0604776 0,09468923 ! negative regulation of translation GO:0017148 22 16 0,000 0,0604776 0,09462481 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,06413542 0,10027972 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,06413542 0,10021159 ! negative regulation of defense response GO:0031348 19 17 0,000 0,06413542 0,10014356 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,06413542 0,10007562 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,06413542 0,10000777 ! glycerol metabolic process GO:0006071 20 17 0,000 0,06413542 0,09994002 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,06413542 0,09987235 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,06413542 0,09980478 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,06413542 0,0997373 ! signal complex assembly GO:0007172 29 17 0,000 0,06413542 0,09966991 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,06413542 0,09960261 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,06413542 0,0995354 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,06413542 0,09946829 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,06413542 0,09940126 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,06413542 0,09933432 ! memory GO:0007613 25 17 0,000 0,06413542 0,09926747 ! keratinization GO:0031424 17 17 0,000 0,06413542 0,09920072 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,06413542 0,09913405 ! retinoid metabolic process GO:0001523 22 17 0,000 0,06413542 0,09906747 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,06413542 0,09900098 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,06413542 0,09893459 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,06413542 0,09886828 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,06413542 0,09880205 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,06413542 0,09873592 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,06413542 0,09866988 ! membrane budding GO:0006900 29 17 0,000 0,06413542 0,09860392 ! heme metabolic process GO:0042168 27 17 0,000 0,06413542 0,09853805 ! actin filament bundle formation GO:0051017 26 17 0,000 0,06413542 0,09847227 ! neuromuscular junction development GO:0007528 23 17 0,000 0,06413542 0,09840658 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,06413542 0,09834098 ! body fluid secretion GO:0007589 27 17 0,000 0,06413542 0,09827546 ! stem cell differentiation GO:0048863 36 17 0,000 0,06413542 0,09821003 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,06413542 0,09814469 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,06413542 0,09807943 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,06413542 0,09801426 ! sensory perception of pain GO:0019233 23 17 0,000 0,06413542 0,09794918 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,06413542 0,09788419 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,06413542 0,09781928 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,06413542 0,09775445 ! synaptogenesis GO:0007416 24 17 0,000 0,06413542 0,09768971 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,06413542 0,09762506 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,06413542 0,09756049 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,06413542 0,09749601 ! cell-cell junction organization GO:0045216 25 17 0,000 0,06413542 0,09743162 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,06413542 0,0973673 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,06413542 0,09730308 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,06413542 0,09723894 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,06413542 0,09717488 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,06413542 0,09711091 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,06413542 0,09704702 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,06777921 0,10249322 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,06777921 0,10242588 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,06777921 0,10235862 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,06777921 0,10229146 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,06777921 0,10222438 ! cAMP metabolic process GO:0046058 33 18 0,000 0,06777921 0,10215739 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,06777921 0,10209049 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,06777921 0,10202368 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,06777921 0,10195695 ! axis specification GO:0009798 26 18 0,000 0,06777921 0,10189032 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,06777921 0,10182376 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,06777921 0,1017573 ! pancreas development GO:0031016 26 18 0,000 0,06777921 0,10169092 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,06777921 0,10162463 ! glutamine metabolic process GO:0006541 23 18 0,000 0,06777921 0,10155843 ! response to retinoic acid GO:0032526 25 18 0,000 0,06777921 0,10149231 ! pigmentation during development GO:0048066 31 18 0,000 0,06777921 0,10142627 ! central nervous system neuron development GO:0021954 30 18 0,000 0,06777921 0,10136033 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,06777921 0,10129447 ! fucose metabolic process GO:0006004 26 18 0,000 0,06777921 0,10122869 ! response to fungus GO:0009620 19 18 0,000 0,06777921 0,101163 ! peptide cross-linking GO:0018149 31 18 0,000 0,06777921 0,1010974 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,06777921 0,10103188 ! heart process GO:0003015 27 18 0,000 0,06777921 0,10096644 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,06777921 0,10090109 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,06777921 0,10083582 ! visual learning GO:0008542 35 18 0,000 0,06777921 0,10077064 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,06777921 0,10070555 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,06777921 0,10064053 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,06777921 0,1005756 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,06777921 0,10051076 ! vitamin transport GO:0051180 24 18 0,000 0,06777921 0,10044599 ! hormone transport GO:0009914 27 18 0,000 0,06777921 0,10038132 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,06777921 0,10031672 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,06777921 0,10025221 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,06777921 0,10018778 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,06777921 0,10012343 ! cell-cell recognition GO:0009988 20 18 0,000 0,06777921 0,10005917 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,06777921 0,09999499 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,06777921 0,09993089 ! regulation of glucose import GO:0046324 21 18 0,000 0,06777921 0,09986687 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,06777921 0,09980293 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,06777921 0,09973908 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,06777921 0,09967531 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,07140902 0,10494617 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,07140902 0,10487915 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,07140902 0,10481222 ! positive regulation of ossification GO:0045778 30 19 0,000 0,07140902 0,10474538 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,07140902 0,10467862 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,07140902 0,10461194 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,07140902 0,10454535 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,07140902 0,10447885 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,07140902 0,10441243 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,07140902 0,10434609 ! regeneration GO:0031099 32 19 0,000 0,07140902 0,10427984 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,07140902 0,10421367 ! sensory perception of taste GO:0050909 23 19 0,000 0,07140902 0,10414759 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,07140902 0,10408159 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,07140902 0,10401567 ! smooth muscle contraction GO:0006939 36 19 0,000 0,07140902 0,10394984 ! peroxisome organization GO:0007031 29 19 0,000 0,07140902 0,10388409 ! digestive system process GO:0022600 30 19 0,000 0,07140902 0,10381842 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,07140902 0,10375284 ! response to vitamin A GO:0033189 26 19 0,000 0,07140902 0,10368734 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,07140902 0,10362192 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,07140902 0,10355659 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,07140902 0,10349133 ! plasma membrane fusion GO:0045026 23 19 0,000 0,07140902 0,10342616 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,07140902 0,10336108 ! cytolysis GO:0019835 20 19 0,000 0,07140902 0,10329607 ! renal system process GO:0003014 35 19 0,000 0,07140902 0,10323114 ! vasodilation GO:0042311 33 19 0,000 0,07140902 0,1031663 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,07140902 0,10310154 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,07140902 0,10303686 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,07140902 0,10297226 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,07140902 0,10290774 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,07140902 0,1028433 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,07140902 0,10277894 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,07140902 0,10271466 ! sarcomere organization GO:0045214 23 19 0,000 0,07140902 0,10265047 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,07140902 0,10258635 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,07140902 0,10252231 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,07140902 0,10245836 ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,07140902 0,10239448 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,07140902 0,10233068 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,07140902 0,10226697 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,07140902 0,10220333 ! protein stabilization GO:0050821 26 19 0,000 0,07140902 0,10213977 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,07502491 0,10724505 ! iron ion transport GO:0006826 37 20 0,000 0,07502491 0,10717844 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,07502491 0,10711191 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,07502491 0,10704546 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,07502491 0,1069791 ! response to vitamin GO:0033273 29 20 0,000 0,07502491 0,10691281 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,07502491 0,10684661 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,07502491 0,1067805 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,07502491 0,10671446 ! spinal cord development GO:0021510 31 20 0,000 0,07502491 0,10664851 ! response to ethanol GO:0045471 37 20 0,000 0,07502491 0,10658263 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,07502491 0,10651684 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,07502491 0,10645113 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,07502491 0,1063855 ! chromosome condensation GO:0030261 31 20 0,000 0,07502491 0,10631995 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,07502491 0,10625448 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,07502491 0,1061891 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,07502491 0,10612379 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,07502491 0,10605856 ! pallium development GO:0021543 38 20 0,000 0,07502491 0,10599342 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,07502491 0,10592835 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,07502491 0,10586336 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,07502491 0,10579846 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,07502491 0,10573363 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,07502491 0,10566888 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,07502491 0,10560421 ! collagen catabolic process GO:0030574 25 20 0,000 0,07502491 0,10553962 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,07502491 0,10547511 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,07502491 0,10541068 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,07502491 0,10534633 ! alditol metabolic process GO:0019400 24 20 0,000 0,07502491 0,10528205 ! actin filament-based movement GO:0030048 34 20 0,000 0,07502491 0,10521785 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,07862692 0,11020226 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,07862692 0,11013514 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,07862692 0,11006811 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,07862692 0,11000116 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,07862692 0,10993429 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,07862692 0,1098675 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,07862692 0,10980079 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,07862692 0,10973417 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,07862692 0,10966762 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,07862692 0,10960116 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,07862692 0,10953477 ! vesicle docking GO:0048278 27 21 0,000 0,07862692 0,10946847 ! phototransduction GO:0007602 25 21 0,000 0,07862692 0,10940224 ! dendrite development GO:0016358 35 21 0,000 0,07862692 0,1093361 ! visual behavior GO:0007632 39 21 0,000 0,07862692 0,10927003 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,07862692 0,10920405 ! ovarian follicle development GO:0001541 30 21 0,000 0,07862692 0,10913814 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,07862692 0,10907232 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,07862692 0,10900657 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,07862692 0,10894091 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,07862692 0,10887532 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,07862692 0,10880981 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,07862692 0,10874438 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,07862692 0,10867903 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,07862692 0,10861376 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,07862692 0,10854856 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,07862692 0,10848345 ! fatty acid transport GO:0015908 30 21 0,000 0,07862692 0,10841841 ! immunoglobulin production GO:0002377 33 21 0,000 0,07862692 0,10835345 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,07862692 0,10828857 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,07862692 0,10822376 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,07862692 0,10815903 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,07862692 0,10809439 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,07862692 0,10802981 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,07862692 0,10796532 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,07862692 0,1079009 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,07862692 0,10783656 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,07862692 0,10777229 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,07862692 0,1077081 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,07862692 0,10764399 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,07862692 0,10757996 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,07862692 0,107516 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,07862692 0,10745211 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,0822151 0,11228904 ! viral genome replication GO:0019079 29 22 0,000 0,0822151 0,1122224 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,0822151 0,11215584 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,0822151 0,11208935 ! leukocyte adhesion GO:0007159 38 22 0,000 0,0822151 0,11202295 ! molting cycle process GO:0022404 40 22 0,000 0,0822151 0,11195663 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! glutamate signaling pathway GO:0007215 34 22 0,000 0,0822151 0,11189038 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,0822151 0,11182421 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,0822151 0,11175812 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,0822151 0,11169211 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,0822151 0,11162618 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,0822151 0,11156032 ! lysosome organization GO:0007040 37 22 0,000 0,0822151 0,11149454 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,0822151 0,11142884 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,0822151 0,11136322 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,0822151 0,11129767 ! regulation of behavior GO:0050795 38 22 0,000 0,0822151 0,1112322 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,0822151 0,11116681 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,0822151 0,11110149 ! membrane depolarization GO:0051899 35 22 0,000 0,0822151 0,11103625 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,0822151 0,11097109 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,0822151 0,11090601 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,0822151 0,110841 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,0822151 0,11077606 ! neural tube closure GO:0001843 33 22 0,000 0,0822151 0,11071121 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,0822151 0,11064643 ! neuron fate commitment GO:0048663 32 23 0,000 0,08578952 0,11538942 ! embryonic pattern specification GO:0009880 31 23 0,000 0,08578952 0,11532198 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,08578952 0,11525462 ! myelination GO:0042552 35 23 0,000 0,08578952 0,11518734 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,08578952 0,11512013 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,08578952 0,11505301 ! vesicle targeting GO:0006903 32 23 0,000 0,08578952 0,11498596 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,08578952 0,11491899 ! osteoblast differentiation GO:0001649 40 23 0,000 0,08578952 0,1148521 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,08578952 0,11478529 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,08578952 0,11471855 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,08578952 0,11465189 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,08578952 0,11458531 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,08578952 0,11451881 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,08578952 0,11445238 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,08578952 0,11438603 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,08578952 0,11431976 ! cell fate determination GO:0001709 45 23 0,000 0,08578952 0,11425357 ! pentose metabolic process GO:0019321 31 23 0,000 0,08578952 0,11418745 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,08578952 0,1141214 ! spermatid development GO:0007286 33 23 0,000 0,08578952 0,11405544 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,08578952 0,11398955 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,08578952 0,11392373 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,08578952 0,113858 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,08578952 0,11379233 ! telomere organization GO:0032200 32 23 0,000 0,08578952 0,11372675 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,08578952 0,11366124 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,08578952 0,1135958 ! regulation of amine transport GO:0051952 38 23 0,000 0,08578952 0,11353044 ! liver development GO:0001889 40 23 0,000 0,08578952 0,11346516 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,08935023 0,11810662 ! initiation of viral infection GO:0019059 42 24 0,000 0,08935023 0,11803878 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,08935023 0,11797102 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,08935023 0,11790334 ! superoxide metabolic process GO:0006801 32 24 0,000 0,08935023 0,11783574 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,08935023 0,11776821 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,08935023 0,11770076 ! fat cell differentiation GO:0045444 37 24 0,000 0,08935023 0,11763339 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,08935023 0,11756609 ! sperm motility GO:0030317 27 24 0,000 0,08935023 0,11749887 ! vacuole organization GO:0007033 39 24 0,000 0,08935023 0,11743173 ! receptor metabolic process GO:0043112 37 24 0,000 0,08935023 0,11736466 ! neural crest cell development GO:0014032 39 24 0,000 0,08935023 0,11729767 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,08935023 0,11723076 ! primary neural tube formation GO:0014020 35 24 0,000 0,08935023 0,11716392 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,08935023 0,11709716 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,08935023 0,11703048 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,08935023 0,11696387 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,08935023 0,11689734 ! glutathione metabolic process GO:0006749 29 24 0,000 0,08935023 0,11683088 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,08935023 0,1167645 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,08935023 0,1166982 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,08935023 0,11663197 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,09289727 0,12119326 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,09289727 0,12112455 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,09289727 0,12105593 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,09289727 0,12098738 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,09289727 0,12091891 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,09289727 0,12085051 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,09289727 0,1207822 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,09289727 0,12071396 ! peptide transport GO:0015833 43 25 0,000 0,09289727 0,1206458 ! male gonad development GO:0008584 33 25 0,000 0,09289727 0,12057771 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,09289727 0,12050971 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,09289727 0,12044178 ! phospholipid transport GO:0015914 35 25 0,000 0,09289727 0,12037392 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,09289727 0,12030614 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,09289727 0,12023844 ! detection of light stimulus GO:0009583 30 25 0,000 0,09289727 0,12017082 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,09289727 0,12010327 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,09289727 0,12003579 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,09289727 0,11996839 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,09643069 0,12446161 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,09643069 0,1243918 ! translational initiation GO:0006413 43 26 0,000 0,09643069 0,12432208 ! circadian rhythm GO:0007623 42 26 0,000 0,09643069 0,12425243 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,09643069 0,12418286 ! post-embryonic development GO:0009791 42 26 0,000 0,09643069 0,12411337 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,09643069 0,12404395 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,09643069 0,12397461 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,09643069 0,12390536 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,09643069 0,12383617 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,09643069 0,12376707 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,09643069 0,12369804 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,09643069 0,12362909 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,09643069 0,12356022 ! regulation of coagulation GO:0050818 39 26 0,000 0,09643069 0,12349142 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,09995055 0,12792781 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,09995055 0,12785666 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,09995055 0,12778559 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,09995055 0,12771459 ! membrane docking GO:0022406 39 27 0,000 0,09995055 0,12764368 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,09995055 0,12757285 ! catechol metabolic process GO:0009712 43 27 0,000 0,09995055 0,12750209 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,09995055 0,12743141 ! acute-phase response GO:0006953 42 27 0,000 0,09995055 0,12736081 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,09995055 0,12729029 ! myofibril assembly GO:0030239 36 27 0,000 0,09995055 0,12721985 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,09995055 0,12714949 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,09995055 0,1270792 ! natural killer cell activation GO:0030101 35 27 0,000 0,09995055 0,12700899 ! lipid oxidation GO:0034440 38 27 0,000 0,09995055 0,12693886 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,09995055 0,1268688 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,09995055 0,12679882 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,09995055 0,12672892 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,09995055 0,1266591 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,09995055 0,12658936 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,09995055 0,12651969 ! gene silencing GO:0016458 41 27 0,000 0,09995055 0,12645009 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,1034569 0,13081412 ! phenol metabolic process GO:0018958 44 28 0,000 0,1034569 0,13074224 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,1034569 0,13067044 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,1034569 0,13059873 ! cell junction assembly GO:0034329 56 28 0,000 0,1034569 0,13052709 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,1034569 0,13045552 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,1034569 0,13038404 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,1034569 0,13031264 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,1034569 0,13024131 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,1034569 0,13017006 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,1034569 0,13009889 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,1034569 0,1300278 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,1034569 0,12995679 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,1034569 0,12988585 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,1034569 0,12981499 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,1034569 0,12974421 ! mesoderm formation GO:0001707 46 28 0,000 0,1034569 0,1296735 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,1034569 0,12960287 ! ensheathment of neurons GO:0007272 43 28 0,000 0,1034569 0,12953232 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,1034569 0,12946185 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,1034569 0,12939145 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,1034569 0,12932113 ! neural tube formation GO:0001841 41 28 0,000 0,1034569 0,12925088 ! regulation of B cell activation GO:0050864 42 28 0,000 0,1034569 0,12918071 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,10694979 0,13346963 ! regulation of innate immune response GO:0045088 38 29 0,000 0,10694979 0,13339725 ! ovulation cycle process GO:0022602 41 29 0,000 0,10694979 0,13332495 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,10694979 0,13325272 ! protein targeting to membrane GO:0006612 53 29 0,000 0,10694979 0,13318058 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,10694979 0,13310851 ! mismatch repair GO:0006298 34 29 0,000 0,10694979 0,13303652 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,10694979 0,13296461 ! muscle cell development GO:0055001 38 29 0,000 0,10694979 0,13289278 ! formation of primary germ layer GO:0001704 48 29 0,000 0,10694979 0,13282102 ! telencephalon development GO:0021537 52 29 0,000 0,10694979 0,13274934 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,10694979 0,13267774 ! eye morphogenesis GO:0048592 51 29 0,000 0,10694979 0,13260621 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,10694979 0,13253477 ! tissue homeostasis GO:0001894 42 29 0,000 0,10694979 0,1324634 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,11042928 0,13669932 ! collagen metabolic process GO:0032963 40 30 0,000 0,11042928 0,13662579 ! organic anion transport GO:0015711 51 30 0,000 0,11042928 0,13655233 ! cholesterol transport GO:0030301 46 30 0,000 0,11042928 0,13647896 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,11042928 0,13640566 ! spliceosome assembly GO:0000245 49 30 0,000 0,11042928 0,13633244 ! spindle organization GO:0007051 37 30 0,000 0,11042928 0,1362593 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,11042928 0,13618624 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,11042928 0,13611326 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,11042928 0,13604035 ! ceramide metabolic process GO:0006672 43 30 0,000 0,11042928 0,13596753 ! ovulation cycle GO:0042698 43 30 0,000 0,11042928 0,13589478 ! hindbrain development GO:0030902 45 30 0,000 0,11042928 0,13582211 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,11042928 0,13574951 ! adult locomotory behavior GO:0008344 47 30 0,000 0,11042928 0,135677 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,11042928 0,13560456 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,11042928 0,1355322 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,11042928 0,13545991 ! response to heat GO:0009408 41 30 0,000 0,11042928 0,13538771 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,11042928 0,13531558 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,11042928 0,13524352 ! negative regulation of secretion GO:0051048 49 31 0,000 0,1138954 0,13941428 ! mammary gland development GO:0030879 57 31 0,000 0,1138954 0,13934012 ! glial cell differentiation GO:0010001 55 31 0,000 0,1138954 0,13926604 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,1138954 0,13919204 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,1138954 0,13911812 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,1138954 0,13904428 ! odontogenesis GO:0042476 50 31 0,000 0,1138954 0,13897052 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,1138954 0,13889683 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,1138954 0,13882322 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,1138954 0,1387497 ! metanephros development GO:0001656 58 31 0,000 0,1138954 0,13867624 ! cell fate specification GO:0001708 37 31 0,000 0,1138954 0,13860287 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,1138954 0,13852957 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,1138954 0,13845636 ! RNA modification GO:0009451 40 31 0,000 0,1138954 0,13838321 ! regulation of muscle development GO:0048634 48 32 0,000 0,11734822 0,14250312 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,11734822 0,14242792 ! meiosis I GO:0007127 52 32 0,000 0,11734822 0,1423528 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,11734822 0,14227776 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,11734822 0,14220279 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,11734822 0,14212791 GO:0006639|acylglycerol metabolic process, ! peripheral nervous system development GO:0007422 53 32 0,000 0,11734822 0,14205311 ! regulation of protein stability GO:0031647 48 32 0,000 0,11734822 0,14197838 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,11734822 0,14190374 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,11734822 0,14182917 ! cytokine production GO:0001816 44 32 0,000 0,11734822 0,14175468 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,11734822 0,14168026 ! vesicle localization GO:0051648 47 32 0,000 0,11734822 0,14160593 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,12078778 0,14568007 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,12078778 0,14560372 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,12078778 0,14552745 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,12078778 0,14545125 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,12078778 0,14537514 ! sister chromatid segregation GO:0000819 46 33 0,000 0,12078778 0,14529911 ! actomyosin structure organization GO:0031032 43 33 0,000 0,12078778 0,14522315 ! cell junction organization GO:0034330 63 33 0,000 0,12078778 0,14514728 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,12078778 0,14507148 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,12078778 0,14499577 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,12078778 0,14492013 ! female gonad development GO:0008585 49 33 0,000 0,12078778 0,14484457 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,12078778 0,14476909 ! positive regulation of cell development GO:0010720 54 33 0,000 0,12078778 0,14469369 ! lipid homeostasis GO:0055088 55 33 0,000 0,12078778 0,14461837 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,12078778 0,14454313 ! regulation of proteolysis GO:0030162 50 33 0,000 0,12078778 0,14446796 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,12078778 0,14439288 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,12078778 0,14431787 ! cytokinesis GO:0000910 52 33 0,000 0,12078778 0,14424293 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,12078778 0,14416808 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,12421413 0,14818076 ! mRNA catabolic process GO:0006402 48 34 0,000 0,12421413 0,14810394 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,12421413 0,1480272 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,12421413 0,14795055 ! feeding behavior GO:0007631 45 34 0,000 0,12421413 0,14787397 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,12421413 0,14779747 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,12421413 0,14772105 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,12421413 0,14764471 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,12421413 0,14756844 ! female gamete generation GO:0007292 43 34 0,000 0,12421413 0,14749226 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,12421413 0,14741615 ! polyol metabolic process GO:0019751 44 34 0,000 0,12421413 0,14734013 ! aerobic respiration GO:0009060 47 34 0,000 0,12421413 0,14726418 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,12421413 0,14718831 ! embryonic organ development GO:0048568 45 34 0,000 0,12421413 0,14711252 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,12421413 0,1470368 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,12762733 0,15099941 ! Notch signaling pathway GO:0007219 56 35 0,000 0,12762733 0,15092178 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,12762733 0,15084422 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,12762733 0,15076675 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,12762733 0,15068935 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,12762733 0,15061203 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,12762733 0,1505348 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,12762733 0,15045764 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,12762733 0,15038056 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,12762733 0,15030356 ! glycogen metabolic process GO:0005977 48 35 0,000 0,12762733 0,15022664 ! pigment metabolic process GO:0042440 61 35 0,000 0,12762733 0,1501498 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,12762733 0,15007303 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,12762733 0,14999635 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,13102742 0,15391372 ! negative regulation of binding GO:0051100 58 36 0,000 0,13102742 0,15383515 ! organic ether metabolic process GO:0018904 46 36 0,000 0,13102742 0,15375666 ! tissue remodeling GO:0048771 62 36 0,000 0,13102742 0,15367825 ! neural tube development GO:0021915 50 36 0,000 0,13102742 0,15359993 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,13102742 0,15352168 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,13102742 0,15344351 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,13102742 0,15336542 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,13102742 0,15328741 ! glucan metabolic process GO:0044042 49 36 0,000 0,13102742 0,15320949 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,13441445 0,15709005 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,13441445 0,15701027 ! learning GO:0007612 67 37 0,000 0,13441445 0,15693057 ! ion transmembrane transport GO:0034220 56 37 0,000 0,13441445 0,15685095 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,13441445 0,15677141 ! regulation of protein secretion GO:0050708 51 37 0,000 0,13441445 0,15669196 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,13441445 0,15661258 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,13778847 0,16046252 ! gliogenesis GO:0042063 71 38 0,000 0,13778847 0,16038132 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,13778847 0,16030019 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,13778847 0,16021915 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,13778847 0,16013819 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,13778847 0,16005731 ! phagocytosis GO:0006909 60 38 0,000 0,13778847 0,15997652 ! mesenchymal cell development GO:0014031 64 38 0,000 0,13778847 0,1598958 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 0,000 0,13778847 0,15981517 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,14114953 0,16363101 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,14114953 0,16354858 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,14114953 0,16346623 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,14114953 0,16338396 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,14114953 0,16330177 ! male sex differentiation GO:0046661 53 39 0,000 0,14114953 0,16321967 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,14114953 0,16313765 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,14114953 0,16305571 ! JNK cascade GO:0007254 54 39 0,000 0,14114953 0,16297386 ! developmental growth GO:0048589 62 39 0,000 0,14114953 0,16289208 ! cell growth GO:0016049 61 39 0,000 0,14114953 0,16281039 ! synapse organization GO:0050808 55 39 0,000 0,14114953 0,16272878 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,14449769 0,16650535 ! response to calcium ion GO:0051592 58 40 0,000 0,14449769 0,16642197 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,14449769 0,16633868 ! regulation of tube size GO:0035150 60 40 0,000 0,14449769 0,16625547 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,14449769 0,16617234 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,14449769 0,16608929 ! peptide metabolic process GO:0006518 56 40 0,000 0,14449769 0,16600633 ! inner ear development GO:0048839 57 40 0,000 0,14449769 0,16592345 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,14449769 0,16584066 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,14449769 0,16575794 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,14449769 0,16567531 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,14783298 0,16941497 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,14783298 0,1693306 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,14783298 0,16924631 ! glucose transport GO:0015758 52 41 0,000 0,14783298 0,16916211 ! endosome transport GO:0016197 71 41 0,000 0,14783298 0,16907799 ! striated muscle contraction GO:0006941 62 41 0,000 0,14783298 0,16899396 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,14783298 0,16891001 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,14783298 0,16882614 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,14783298 0,16874236 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,15115546 0,17244918 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,15115546 0,17236368 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,15115546 0,17227827 ! hexose transport GO:0008645 54 42 0,000 0,15115546 0,17219294 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,15115546 0,1721077 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,15115546 0,17202254 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,15115546 0,17193746 ! excretion GO:0007588 63 42 0,000 0,15115546 0,17185247 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,15115546 0,17176756 ! regulation of cell shape GO:0008360 78 42 0,000 0,15115546 0,17168274 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,15446517 0,17535533 ! leukocyte migration GO:0050900 60 43 0,000 0,15446517 0,17526882 ! neuromuscular process GO:0050905 79 43 0,000 0,15446517 0,17518239 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,15446517 0,17509605 ! tRNA processing GO:0008033 49 43 0,000 0,15446517 0,1750098 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,15446517 0,17492363 ! vesicle organization GO:0016050 79 43 0,000 0,15446517 0,17483755 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,15446517 0,17475155 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,15776217 0,1783938 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,15776217 0,17830614 ! glycolysis GO:0006096 53 44 0,000 0,15776217 0,17821856 ! regulation of action potential GO:0001508 71 44 0,000 0,15776217 0,17813107 ! regulation of ion transport GO:0043269 57 44 0,000 0,15776217 0,17804367 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,15776217 0,17795635 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,15776217 0,17786911 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,15776217 0,17778197 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,15776217 0,1776949 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,15776217 0,17760793 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,15776217 0,17752103 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,15776217 0,17743423 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,1610465 0,18103957 ! RNA catabolic process GO:0006401 64 45 0,000 0,1610465 0,18095113 ! positive regulation of defense response GO:0031349 59 45 0,000 0,1610465 0,18086277 ! regulation of translational initiation GO:0006446 64 45 0,000 0,1610465 0,1807745 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,1610465 0,18068632 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,1610465 0,18059822 ! cell recognition GO:0008037 58 45 0,000 0,1610465 0,18051021 ! cell maturation GO:0048469 60 45 0,000 0,1610465 0,18042229 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,16431821 0,183998 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,16431821 0,18390846 ! regulation of ossification GO:0030278 71 46 0,000 0,16431821 0,18381901 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,16431821 0,18372965 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,16757735 0,18728276 ! viral infectious cycle GO:0019058 71 47 0,000 0,16757735 0,1871918 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,16757735 0,18710093 ! endocrine system development GO:0035270 83 47 0,000 0,16757735 0,18701015 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,16757735 0,18691945 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,16757735 0,18682885 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,16757735 0,18673833 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,16757735 0,1866479 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 0,000 0,16757735 0,18655756 ! chloride transport GO:0006821 67 48 0,000 0,17082397 0,19007989 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,17082397 0,18998797 ! response to temperature stimulus GO:0009266 62 48 0,000 0,17082397 0,18989615 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,17082397 0,18980441 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,17082397 0,18971276 ! gastrulation GO:0007369 73 48 0,000 0,17082397 0,1896212 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,17082397 0,18952973 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,17082397 0,18943835 ! regulation of endocytosis GO:0030100 63 48 0,000 0,17082397 0,18934705 ! nuclear export GO:0051168 69 48 0,000 0,17082397 0,18925584 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,17082397 0,18916472 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,17082397 0,18907369 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,17405811 0,19256068 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,17405811 0,1924681 ! sensory perception of smell GO:0007608 61 49 0,000 0,17405811 0,19237561 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,17405811 0,19228321 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,17405811 0,1921909 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,17405811 0,19209868 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,17405811 0,19200654 ! germ cell development GO:0007281 68 49 0,000 0,17405811 0,1919145 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,17405811 0,19182254 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,17405811 0,19173067 ! cartilage development GO:0051216 70 49 0,000 0,17405811 0,19163889 ! maintenance of location GO:0051235 84 49 0,000 0,17405811 0,1915472 ! regulation of actin filament length GO:0030832 72 50 0,000 0,17727982 0,19499932 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,17727982 0,19490611 ! membrane fusion GO:0006944 80 50 0,000 0,17727982 0,19481298 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,17727982 0,19471995 ! proton transport GO:0015992 75 50 0,000 0,17727982 0,19462701 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,17727982 0,19453415 ! positive regulation of secretion GO:0051047 71 51 0,000 0,18048914 0,19796139 ! hydrogen transport GO:0006818 77 51 0,000 0,18048914 0,19786703 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,18048914 0,19777276 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,18048914 0,19767858 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,18048914 0,1975845 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,18048914 0,1974905 ! adult behavior GO:0030534 80 51 0,000 0,18048914 0,19739659 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,18048914 0,19730277 ! transition metal ion transport GO:0000041 74 52 0,000 0,18368613 0,20070219 ! regulation of cellular component size GO:0032535 74 52 0,000 0,18368613 0,20060689 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,18368613 0,20051168 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,18368613 0,20041656 ! establishment of organelle localization GO:0051656 85 52 0,000 0,18368613 0,20032153 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,18687083 0,20369806 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,18687083 0,20360157 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,18687083 0,20350517 ! kidney development GO:0001822 90 53 0,000 0,18687083 0,20340886 ! single fertilization GO:0007338 59 53 0,000 0,18687083 0,20331264 ! amino acid transport GO:0006865 84 54 0,000 0,19004329 0,20666646 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,19004329 0,2065688 ! regulation of mitosis GO:0007088 84 54 0,000 0,19004329 0,20647122 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,19004329 0,20637374 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,19004329 0,20627634 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,19004329 0,20617904 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,19004329 0,20608183 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,19004329 0,20598472 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,19004329 0,20588769 ! exocytosis GO:0006887 74 55 0,000 0,19320355 0,20921289 ! mesoderm development GO:0007498 76 55 0,000 0,19320355 0,20911444 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,19320355 0,20901608 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,19320355 0,20891781 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,19635167 0,2122222 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,19635167 0,21212252 ! carbohydrate transport GO:0008643 74 57 0,000 0,19948768 0,21540923 ! chromosome segregation GO:0007059 83 57 0,000 0,19948768 0,21530814 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,19948768 0,21520716 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,19948768 0,21510626 ! camera-type eye development GO:0043010 88 57 0,000 0,19948768 0,21500546 ! secondary metabolic process GO:0019748 84 57 0,000 0,19948768 0,21490476 ! developmental maturation GO:0021700 75 57 0,000 0,19948768 0,21480415 ! gonad development GO:0008406 79 57 0,000 0,19948768 0,21470363 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,20261163 0,21796386 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,20261163 0,21786196 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,20261163 0,21776016 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,20572356 0,22100149 ! actin filament organization GO:0007015 95 59 0,000 0,20572356 0,22089832 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,20572356 0,22079524 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,20572356 0,22069226 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,20882354 0,22391335 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,20882354 0,22380901 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,20882354 0,22370477 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,20882354 0,22360062 ! regulation of heart contraction GO:0008016 91 60 0,000 0,20882354 0,22349657 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,20882354 0,22339262 ! fertilization GO:0009566 68 60 0,000 0,20882354 0,22328876 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,21191159 0,22648543 ! meiosis GO:0007126 96 61 0,000 0,21191159 0,22638024 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,21191159 0,22627514 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,21191159 0,22617014 ! urogenital system development GO:0001655 101 61 0,000 0,21191159 0,22606523 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,21191159 0,22596043 ! extracellular matrix organization GO:0030198 103 61 0,000 0,21191159 0,22585572 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,21191159 0,22575111 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,21191159 0,2256466 ! amine catabolic process GO:0009310 90 62 0,000 0,21498776 0,22881622 ! neurotransmitter transport GO:0006836 81 62 0,000 0,21498776 0,22871038 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,21498776 0,22860464 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,21498776 0,228499 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,21498776 0,22839346 ! meiotic cell cycle GO:0051321 97 62 0,000 0,21498776 0,22828802 ! organelle localization GO:0051640 96 62 0,000 0,21498776 0,22818267 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,2180521 0,23132834 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,2180521 0,23122168 ! regulation of lipase activity GO:0060191 109 63 0,000 0,2180521 0,23111513 ! appendage morphogenesis GO:0035107 93 64 0,000 0,22110466 0,23424261 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,22110466 0,23413476 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,22110466 0,23402702 ! hexose catabolic process GO:0019320 82 64 0,000 0,22110466 0,23391937 ! adaptive immune response GO:0002250 94 64 0,000 0,22110466 0,23381182 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,22414547 0,23691846 ! appendage development GO:0048736 94 65 0,000 0,22414547 0,23680964 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,22414547 0,23670091 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,22414547 0,23659228 ! defense response to bacterium GO:0042742 73 65 0,000 0,22414547 0,23648375 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,22414547 0,23637532 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,22414547 0,23626699 ! activation of immune response GO:0002253 83 65 0,000 0,22414547 0,23615876 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,22717458 0,23924063 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,22717458 0,23913114 ! antigen processing and presentation GO:0019882 96 66 0,000 0,22717458 0,23902175 ! axon guidance GO:0007411 99 66 0,000 0,22717458 0,23891246 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,22717458 0,23880326 ! regulation of immune effector process GO:0002697 101 66 0,000 0,22717458 0,23869417 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,23019205 0,2417542 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,23019205 0,24164386 ! acute inflammatory response GO:0002526 92 68 0,000 0,2331979 0,24468758 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,2331979 0,244576 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,2331979 0,24446453 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,2331979 0,24435315 ! rhythmic process GO:0048511 105 68 0,000 0,2331979 0,24424188 ! inorganic anion transport GO:0015698 93 68 0,000 0,2331979 0,24413071 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,23619219 0,24715288 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,23619219 0,24704049 ! response to metal ion GO:0010038 103 70 0,000 0,23917496 0,25004655 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,23917496 0,24993294 ! humoral immune response GO:0006959 86 70 0,000 0,23917496 0,24981944 ! amine transport GO:0015837 101 70 0,000 0,23917496 0,24970604 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,24214625 0,25269345 ! muscle cell differentiation GO:0042692 104 71 0,000 0,24214625 0,25257885 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,24214625 0,25246436 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,24214625 0,25234996 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,24214625 0,25223567 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,24214625 0,25212149 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,2451061 0,2550878 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,2451061 0,25497243 ! negative regulation of transport GO:0051051 116 73 0,000 0,24805457 0,25792292 ! regulation of blood pressure GO:0008217 107 73 0,000 0,24805457 0,25780637 ! tube morphogenesis GO:0035239 118 73 0,000 0,24805457 0,25768993 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,24805457 0,25757359 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,24805457 0,25745736 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,25099169 0,26038831 ! digestion GO:0007586 97 74 0,000 0,25099169 0,26027091 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,25099169 0,26015362 ! blood coagulation GO:0007596 116 75 0,000 0,2539175 0,26306768 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,2539175 0,26294923 ! response to nutrient GO:0007584 104 75 0,000 0,2539175 0,2628309 ! regulation of ligase activity GO:0051340 114 75 0,000 0,2539175 0,26271266 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,2539175 0,26259454 ! amine biosynthetic process GO:0009309 97 76 0,000 0,25683205 0,26548931 ! response to unfolded protein GO:0006986 99 76 0,000 0,25683205 0,26537005 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,25683205 0,26525088 ! regulation of protein transport GO:0051223 114 76 0,000 0,25683205 0,26513183 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,25973539 0,2680087 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,25973539 0,26788851 ! gland development GO:0048732 148 77 0,000 0,25973539 0,26776844 ! sex differentiation GO:0007548 105 77 0,000 0,25973539 0,26764847 ! protein ubiquitination GO:0016567 125 77 0,000 0,25973539 0,26752861 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,25973539 0,26740886 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,25973539 0,26728921 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,26262754 0,27014461 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,26262754 0,27002385 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,26550857 0,27286403 ! cellular respiration GO:0045333 107 79 0,000 0,26550857 0,27274216 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,26550857 0,2726204 ! regulation of lyase activity GO:0051339 133 79 0,000 0,26550857 0,27249875 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,26550857 0,27237721 ! alcohol catabolic process GO:0046164 104 80 0,000 0,2683785 0,27519864 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,2683785 0,275076 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,2683785 0,27495347 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,27123738 0,27775867 ! hemostasis GO:0007599 125 81 0,000 0,27123738 0,27763506 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,27123738 0,27751155 ! response to protein stimulus GO:0051789 111 81 0,000 0,27123738 0,27738816 ! regulation of neurological system process GO:0031644 122 81 0,000 0,27123738 0,27726488 ! vitamin metabolic process GO:0006766 103 81 0,000 0,27123738 0,2771417 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,27123738 0,27701864 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,27408525 0,27980297 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,27692216 0,28257363 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,27692216 0,28244832 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,27692216 0,28232313 ! regulation of defense response GO:0031347 117 84 0,000 0,27974815 0,28507786 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,27974815 0,28495161 ! sterol metabolic process GO:0016125 120 84 0,000 0,27974815 0,28482547 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,28256325 0,28756437 ! rRNA metabolic process GO:0016072 107 85 0,000 0,28256325 0,28743718 GO:0006364|rRNA processing, ! regulation of protein localization GO:0032880 132 85 0,000 0,28256325 0,28731011 ! regulation of membrane potential GO:0042391 128 85 0,000 0,28256325 0,28718315 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,28256325 0,2870563 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,28536751 0,28977716 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,28536751 0,28964928 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,28816096 0,29235563 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,28816096 0,29222673 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,29094366 0,29491865 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,29094366 0,29478873 ! interphase GO:0051325 159 88 0,000 0,29094366 0,29465893 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,29094366 0,29452924 GO:0016054|organic acid catabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,29371564 0,29720457 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,29371564 0,29707387 ! regulation of T cell activation GO:0050863 128 89 0,000 0,29371564 0,29694329 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,29647695 0,29960324 ! hormone metabolic process GO:0042445 121 90 0,000 0,29647695 0,29947166 ! ATP metabolic process GO:0046034 137 91 0,000 0,29922761 0,30211743 ! response to virus GO:0009615 122 91 0,000 0,29922761 0,30198487 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,30196768 0,30461652 ! positive regulation of immune response GO:0050778 121 92 0,000 0,30196768 0,30448297 ! DNA recombination GO:0006310 146 92 0,000 0,30196768 0,30434955 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,30469719 0,30696607 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,30469719 0,30683167 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,30469719 0,30669739 ! electron transport chain GO:0022900 123 94 0,000 0,30741619 0,30929887 ! carboxylic acid transport GO:0046942 147 95 0,000 0,3101247 0,31188755 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,31282278 0,31446346 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,31282278 0,31432608 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,31282278 0,31418882 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,31551047 0,31674992 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,31551047 0,31661172 ! calcium ion transport GO:0006816 167 99 0,000 0,3208548 0,32183429 ! extracellular structure organization GO:0043062 156 99 0,000 0,3208548 0,321694 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,3208548 0,32155383 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,32351152 0,32407513 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,32351152 0,32393405 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,32351152 0,32379308 ! divalent metal ion transport GO:0070838 171 100 0,000 0,32351152 0,32365224 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,32351152 0,32351152