pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1137-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 10 5 3,000 1,497E-08 3,443E-05 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 6,000 2,907E-08 3,342E-05 ! regulation of lipid kinase activity GO:0043550 12 7 3,000 1,036E-07 7,941E-05 ! establishment of nucleus localization GO:0040023 13 7 3,000 1,036E-07 5,956E-05 ! apoptotic mitochondrial changes GO:0008637 29 18 4,000 1,734E-07 7,975E-05 ! induction of positive chemotaxis GO:0050930 14 8 3,000 2,06E-07 7,895E-05 ! negative regulation of protein kinase activity GO:0006469 99 57 6,000 2,186E-07 7,182E-05 ! negative regulation of kinase activity GO:0033673 100 58 6,000 2,471E-07 7,103E-05 ! interphase of mitotic cell cycle GO:0051329 156 86 7,000 2,605E-07 6,658E-05 ! interphase GO:0051325 159 88 7,000 3,117E-07 7,169E-05 ! negative regulation of transferase activity GO:0051348 105 61 6,000 3,519E-07 7,357E-05 ! nucleus localization GO:0051647 15 9 3,000 3,686E-07 7,064E-05 ! induction of apoptosis by intracellular signals GO:0008629 67 40 5,000 4,914E-07 8,695E-05 ! negative regulation of cell size GO:0045792 108 64 6,000 4,918E-07 8,079E-05 ! negative regulation of phosphorylation GO:0042326 41 23 4,000 6,607E-07 1,013E-04 ! insulin receptor signaling pathway GO:0008286 40 24 4,000 8,296E-07 1,193E-04 ! regulation of positive chemotaxis GO:0050926 17 11 3,000 9,541E-07 1,291E-04 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of phosphorus metabolic process GO:0010563 45 25 4,000 1,031E-06 1,317E-04 GO:0045936|negative regulation of phosphate metabolic process, ! response to UV GO:0009411 75 46 5,000 1,156E-06 1,399E-04 ! microspike assembly GO:0030035 23 12 3,000 1,423E-06 1,636E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 5,000 2,155E-06 2,361E-04 ! aging GO:0007568 79 52 5,000 2,422E-06 2,532E-04 ! regulation of cell cycle process GO:0010564 122 81 6,000 2,477E-06 2,477E-04 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 2,000 4,067E-06 3,898E-04 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 4,067E-06 3,742E-04 GO:0031272|regulation of pseudopodium assembly, ! response to peptide hormone stimulus GO:0043434 84 57 5,000 4,186E-06 3,703E-04 ! cellular response to insulin stimulus GO:0032869 52 34 4,000 5,114E-06 4,357E-04 ! negative regulation of cell growth GO:0030308 106 62 5,000 6,878E-06 5,65E-04 ! macrophage differentiation GO:0030225 10 6 2,000 8,09E-06 6,416E-04 ! cell cycle checkpoint GO:0000075 108 64 5,000 8,287E-06 6,353E-04 ! positive regulation of locomotion GO:0040017 35 20 3,000 1,329E-05 9,863E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 2,000 1,408E-05 1,012E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,408E-05 9,814E-04 ! B cell lineage commitment GO:0002326 17 7 2,000 1,408E-05 9,525E-04 ! T cell lineage commitment GO:0002360 12 7 2,000 1,408E-05 9,253E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 5,000 1,517E-05 9,689E-04 ! regulation of chemotaxis GO:0050920 36 21 3,000 1,633E-05 1,015E-03 ! cell aging GO:0007569 32 21 3,000 1,633E-05 9,882E-04 ! cellular response to extracellular stimulus GO:0031668 32 21 3,000 1,633E-05 9,628E-04 ! response to insulin stimulus GO:0032868 63 43 4,000 1,676E-05 9,638E-04 ! regulation of cell-matrix adhesion GO:0001952 51 22 3,000 1,984E-05 1,113E-03 GO:0010810|regulation of cell-substrate adhesion, ! regulation of behavior GO:0050795 38 22 3,000 1,984E-05 1,086E-03 ! protein tetramerization GO:0051262 39 22 3,000 1,984E-05 1,061E-03 ! negative regulation of growth GO:0045926 123 75 5,000 2,081E-05 1,088E-03 ! regulation of ligase activity GO:0051340 114 75 5,000 2,081E-05 1,063E-03 ! positive regulation of cell cycle GO:0045787 77 45 4,000 2,102E-05 1,051E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 2,24E-05 1,096E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 2,24E-05 1,074E-03 ! regulation of DNA replication GO:0006275 75 48 4,000 2,894E-05 1,358E-03 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 3,342E-05 1,537E-03 ! thymus development GO:0048538 15 9 2,000 3,342E-05 1,507E-03 ! response to nicotine GO:0035094 16 9 2,000 3,342E-05 1,478E-03 ! establishment of organelle localization GO:0051656 85 52 4,000 4,288E-05 1,861E-03 ! cell cycle arrest GO:0007050 150 86 5,000 4,543E-05 1,935E-03 ! cell projection assembly GO:0030031 76 53 4,000 4,707E-05 1,968E-03 ! regulation of B cell proliferation GO:0030888 15 10 2,000 4,749E-05 1,95E-03 ! regulation of cell projection assembly GO:0060491 20 10 2,000 4,749E-05 1,916E-03 ! regulation of mitosis GO:0007088 84 54 4,000 5,156E-05 2,045E-03 GO:0051783|regulation of nuclear division, ! leukocyte differentiation GO:0002521 143 90 5,000 5,87E-05 2,288E-03 ! filopodium assembly GO:0046847 19 11 2,000 6,493E-05 2,489E-03 ! chondrocyte differentiation GO:0002062 17 11 2,000 6,493E-05 2,448E-03 ! focal adhesion formation GO:0048041 24 11 2,000 6,493E-05 2,409E-03 ! T cell homeostasis GO:0043029 20 11 2,000 6,493E-05 2,371E-03 ! regulation of leukocyte migration GO:0002685 24 11 2,000 6,493E-05 2,334E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 6,493E-05 2,298E-03 GO:0010829|negative regulation of glucose transport, ! peptidyl-amino acid modification GO:0018193 147 93 5,000 7,056E-05 2,459E-03 ! response to heat GO:0009408 41 30 3,000 7,095E-05 2,436E-03 ! response to light stimulus GO:0009416 153 96 5,000 8,426E-05 2,85E-03 ! positive regulation of cellular catabolic process GO:0031331 22 12 2,000 8,611E-05 2,87E-03 ! response to gamma radiation GO:0010332 20 12 2,000 8,611E-05 2,829E-03 ! regulation of protein stability GO:0031647 48 32 3,000 9,203E-05 2,981E-03 ! homeostasis of number of cells GO:0048872 84 61 4,000 9,301E-05 2,971E-03 ! negative regulation of ligase activity GO:0051352 91 61 4,000 9,301E-05 2,93E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 4,000 9,301E-05 2,891E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 4,000 1,006E-04 3,084E-03 ! organelle localization GO:0051640 96 62 4,000 1,006E-04 3,043E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 1,113E-04 3,325E-03 ! lymphocyte homeostasis GO:0002260 24 13 2,000 1,113E-04 3,283E-03 ! mitotic cell cycle checkpoint GO:0007093 63 34 3,000 1,173E-04 3,416E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 4,000 1,261E-04 3,625E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 4,000 1,261E-04 3,58E-03 ! protein oligomerization GO:0051259 100 65 4,000 1,261E-04 3,536E-03 ! cell-substrate adhesion GO:0031589 121 66 4,000 1,356E-04 3,758E-03 ! negative regulation of bone remodeling GO:0046851 26 14 2,000 1,409E-04 3,858E-03 ! catecholamine biosynthetic process GO:0042423 23 14 2,000 1,409E-04 3,813E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,409E-04 3,769E-03 ! positive regulation of ligase activity GO:0051351 99 69 4,000 1,675E-04 4,428E-03 ! negative regulation of cell cycle process GO:0010948 24 15 2,000 1,752E-04 4,578E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 1,752E-04 4,527E-03 ! peptidyl-serine phosphorylation GO:0018105 23 15 2,000 1,752E-04 4,477E-03 ! negative regulation of tissue remodeling GO:0034104 27 15 2,000 1,752E-04 4,427E-03 ! response to metal ion GO:0010038 103 70 4,000 1,793E-04 4,483E-03 ! response to hypoxia GO:0001666 132 72 4,000 2,048E-04 5,066E-03 ! G1 phase GO:0051318 27 16 2,000 2,144E-04 5,246E-03 ! neutrophil chemotaxis GO:0030593 21 16 2,000 2,144E-04 5,191E-03 ! negative regulation of translation GO:0017148 22 16 2,000 2,144E-04 5,137E-03 ! mitochondrion organization GO:0007005 104 73 4,000 2,186E-04 5,183E-03 ! positive regulation of response to external stimulus GO:0032103 65 40 3,000 2,233E-04 5,24E-03 ! T cell differentiation GO:0030217 65 40 3,000 2,233E-04 5,188E-03 ! response to oxygen levels GO:0070482 137 74 4,000 2,33E-04 5,359E-03 ! cellular response to hormone stimulus GO:0032870 109 74 4,000 2,33E-04 5,306E-03 ! response to inorganic substance GO:0010035 115 75 4,000 2,482E-04 5,596E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 2,589E-04 5,782E-03 ! cell-substrate junction assembly GO:0007044 39 17 2,000 2,589E-04 5,727E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 2,589E-04 5,672E-03 ! peptidyl-serine modification GO:0018209 27 17 2,000 2,589E-04 5,619E-03 ! negative regulation of homeostatic process GO:0032845 28 17 2,000 2,589E-04 5,566E-03 ! positive regulation of DNA replication GO:0045740 29 18 2,000 3,09E-04 6,581E-03 ! cellular response to nutrient levels GO:0031669 27 18 2,000 3,09E-04 6,521E-03 ! regulation of glucose import GO:0046324 21 18 2,000 3,09E-04 6,462E-03 GO:0010827|regulation of glucose transport, ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 2,000 3,09E-04 6,403E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 4,000 3,355E-04 6,89E-03 GO:0010498|proteasomal protein catabolic process, ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 3,537E-04 7,198E-03 ! response to alkaloid GO:0043279 32 19 2,000 3,65E-04 7,363E-03 ! sex determination GO:0007530 29 19 2,000 3,65E-04 7,299E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 4,27E-04 8,467E-03 ! positive regulation of inflammatory response GO:0050729 30 20 2,000 4,27E-04 8,395E-03 ! regulation of DNA metabolic process GO:0051052 135 85 4,000 4,443E-04 8,661E-03 ! response to temperature stimulus GO:0009266 62 48 3,000 4,539E-04 8,773E-03 ! germ cell development GO:0007281 68 49 3,000 4,914E-04 9,419E-03 ! myeloid leukocyte differentiation GO:0002573 33 21 2,000 4,955E-04 9,418E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 4,955E-04 9,341E-03 ! activation of pro-apoptotic gene products GO:0008633 36 21 2,000 4,955E-04 9,265E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 4,955E-04 9,19E-03 ! platelet activation GO:0030168 28 21 2,000 4,955E-04 9,117E-03 ! positive regulation of growth GO:0045927 67 50 3,000 5,311E-04 9,694E-03 ! reproductive developmental process GO:0003006 127 89 4,000 5,49E-04 9,943E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 5,491E-04 9,866E-03 ! protein maturation by protein folding GO:0022417 12 5 1,000 5,491E-04 9,79E-03 ! apoptotic cell clearance GO:0043277 13 5 1,000 5,491E-04 9,714E-03 ! lipoprotein particle clearance GO:0034381 9 5 1,000 5,491E-04 9,64E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 5,491E-04 9,567E-03 ! parathyroid gland development GO:0060017 8 5 1,000 5,491E-04 9,495E-03 ! anagen GO:0042640 6 5 1,000 5,491E-04 9,424E-03 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 5,491E-04 9,355E-03 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 1,000 5,491E-04 9,286E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! epithelial cell proliferation GO:0050673 6 5 1,000 5,491E-04 9,218E-03 ! microvillus organization GO:0032528 7 5 1,000 5,491E-04 9,151E-03 GO:0030033|microvillus assembly, ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 1,000 5,491E-04 9,085E-03 ! response to food GO:0032094 5 5 1,000 5,491E-04 9,021E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 1,000 5,491E-04 8,957E-03 ! peptidyl-threonine phosphorylation GO:0018107 14 5 1,000 5,491E-04 8,894E-03 ! homeostasis of number of cells within a tissue GO:0048873 9 5 1,000 5,491E-04 8,831E-03 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 1,000 5,491E-04 8,77E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 5,491E-04 8,71E-03 ! porphyrin catabolic process GO:0006787 12 5 1,000 5,491E-04 8,65E-03 GO:0033015|tetrapyrrole catabolic process, ! triglyceride catabolic process GO:0019433 6 5 1,000 5,491E-04 8,591E-03 ! regulation of mitochondrial depolarization GO:0051900 9 5 1,000 5,491E-04 8,533E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 5,491E-04 8,476E-03 ! hemopoietic progenitor cell differentiation GO:0002244 10 5 1,000 5,491E-04 8,419E-03 ! protein import into nucleus, translocation GO:0000060 36 22 2,000 5,706E-04 8,691E-03 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 5,706E-04 8,634E-03 ! molting cycle process GO:0022404 40 22 2,000 5,706E-04 8,577E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! vasculogenesis GO:0001570 33 22 2,000 5,706E-04 8,522E-03 ! leukocyte homeostasis GO:0001776 33 22 2,000 5,706E-04 8,467E-03 ! positive regulation of cell migration GO:0030335 92 51 3,000 5,73E-04 8,447E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 6,526E-04 9,56E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 6,526E-04 9,5E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 2,000 6,526E-04 9,44E-03 ! regulation of binding GO:0051098 151 95 4,000 7,395E-04 0,01063027 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 7,417E-04 0,01059628 ! regulation of cellular catabolic process GO:0031329 36 24 2,000 7,417E-04 0,01053087 ! mitochondrial membrane organization GO:0007006 39 24 2,000 7,417E-04 0,01046626 ! DNA damage response, signal transduction GO:0042770 96 56 3,000 8,181E-04 0,01147393 ! regulation of lipid metabolic process GO:0019216 84 56 3,000 8,181E-04 0,01140439 ! positive regulation of cell motion GO:0051272 99 56 3,000 8,181E-04 0,01133569 ! regulation of helicase activity GO:0051095 11 6 1,000 8,196E-04 0,01128754 ! prostate gland development GO:0030850 9 6 1,000 8,196E-04 0,01122036 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 8,196E-04 0,01115396 ! mRNA stabilization GO:0048255 15 6 1,000 8,196E-04 0,01108835 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 1,000 8,196E-04 0,01102351 GO:0031958|corticosteroid receptor signaling pathway, ! cGMP-mediated signaling GO:0019934 10 6 1,000 8,196E-04 0,01095942 ! pigment granule organization GO:0048753 11 6 1,000 8,196E-04 0,01089607 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 8,196E-04 0,01083345 ! ER overload response GO:0006983 7 6 1,000 8,196E-04 0,01077154 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 8,196E-04 0,01071034 ! glycerol ether catabolic process GO:0044269 8 6 1,000 8,196E-04 0,01064983 GO:0046464|acylglycerol catabolic process, ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 1,000 8,196E-04 0,01059 ! male sex determination GO:0030238 9 6 1,000 8,196E-04 0,01053084 ! negative regulation of translational initiation GO:0045947 7 6 1,000 8,196E-04 0,01047233 ! spindle checkpoint GO:0031577 14 6 1,000 8,196E-04 0,01041447 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 8,196E-04 0,01035725 ! hair follicle maturation GO:0048820 7 6 1,000 8,196E-04 0,01030065 ! regulation of myeloid cell apoptosis GO:0033032 10 6 1,000 8,196E-04 0,01024467 ! regulation of meiosis GO:0040020 10 6 1,000 8,196E-04 0,0101893 GO:0051445|regulation of meiotic cell cycle, ! regulation of mast cell activation GO:0033003 6 6 1,000 8,196E-04 0,01013452 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 8,196E-04 0,01008032 ! negative regulation of B cell activation GO:0050869 9 6 1,000 8,196E-04 0,0100267 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 8,196E-04 9,974E-03 ! male gonad development GO:0008584 33 25 2,000 8,383E-04 0,0101477 ! peptidyl-tyrosine modification GO:0018212 37 25 2,000 8,383E-04 0,01009457 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 4,000 8,914E-04 0,01067798 ! regulation of translation GO:0006417 151 100 4,000 9,327E-04 0,01111542 ! steroid hormone receptor signaling pathway GO:0030518 96 58 3,000 9,342E-04 0,01107588 ! negative regulation of protein modification process GO:0031400 50 26 2,000 9,425E-04 0,01111623 ! myeloid cell differentiation GO:0030099 85 59 3,000 9,964E-04 0,01169256 ! catechol metabolic process GO:0009712 43 27 2,000 1,054E-03 0,01231132 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to ionizing radiation GO:0010212 47 27 2,000 1,054E-03 0,01224914 ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 1,054E-03 0,01218759 ! negative regulation of transcription regulator activity GO:0090048 47 27 2,000 1,054E-03 0,01212665 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 3,000 1,061E-03 0,0121459 ! cell-matrix adhesion GO:0007160 114 61 3,000 1,129E-03 0,01285958 ! urogenital system development GO:0001655 101 61 3,000 1,129E-03 0,01279623 ! neutral lipid catabolic process GO:0046461 9 7 1,000 1,142E-03 0,01287291 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 1,142E-03 0,01281012 ! lipoprotein transport GO:0042953 9 7 1,000 1,142E-03 0,01274793 ! T-helper 1 type immune response GO:0042088 11 7 1,000 1,142E-03 0,01268635 ! glycerolipid catabolic process GO:0046503 9 7 1,000 1,142E-03 0,01262536 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 1,000 1,142E-03 0,01256495 ! regulation of pigmentation during development GO:0048070 15 7 1,000 1,142E-03 0,01250511 ! organ growth GO:0035265 11 7 1,000 1,142E-03 0,01244585 ! behavioral fear response GO:0001662 13 7 1,000 1,142E-03 0,01238714 GO:0002209|behavioral defense response, ! protein heterooligomerization GO:0051291 10 7 1,000 1,142E-03 0,01232899 ! response to UV-B GO:0010224 11 7 1,000 1,142E-03 0,01227137 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 1,142E-03 0,0122143 ! mast cell activation GO:0045576 9 7 1,000 1,142E-03 0,01215775 ! positive regulation of monooxygenase activity GO:0032770 11 7 1,000 1,142E-03 0,01210172 ! synaptic vesicle endocytosis GO:0048488 16 7 1,000 1,142E-03 0,01204621 ! response to tumor cell GO:0002347 12 7 1,000 1,142E-03 0,01199121 ! peptidyl-threonine modification GO:0018210 18 7 1,000 1,142E-03 0,0119367 ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 1,142E-03 0,01188269 ! muscle adaptation GO:0043500 12 7 1,000 1,142E-03 0,01182916 ! phenol metabolic process GO:0018958 44 28 2,000 1,175E-03 0,01211466 ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 1,175E-03 0,01206057 ! cell junction assembly GO:0034329 56 28 2,000 1,175E-03 0,01200697 ! response to organic cyclic substance GO:0014070 47 28 2,000 1,175E-03 0,01195384 ! positive regulation of multicellular organism growth GO:0040018 38 28 2,000 1,175E-03 0,01190118 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 1,175E-03 0,01184898 ! positive regulation of catabolic process GO:0009896 40 28 2,000 1,175E-03 0,01179724 ! placenta development GO:0001890 37 28 2,000 1,175E-03 0,01174595 ! regulation of B cell activation GO:0050864 42 28 2,000 1,175E-03 0,0116951 ! regulation of transcription factor activity GO:0051090 97 63 3,000 1,274E-03 0,01263394 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 3,000 1,274E-03 0,01257972 ! response to hydrogen peroxide GO:0042542 42 29 2,000 1,303E-03 0,01280715 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 3,000 1,352E-03 0,01322777 ! reproductive structure development GO:0048608 90 65 3,000 1,432E-03 0,01395486 ! negative regulation of cell activation GO:0050866 44 30 2,000 1,44E-03 0,01397353 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,515E-03 0,01463973 ! melanin metabolic process GO:0006582 12 8 1,000 1,515E-03 0,01457847 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 1,515E-03 0,01451773 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,515E-03 0,01445749 ! positive regulation of vasodilation GO:0045909 12 8 1,000 1,515E-03 0,01439775 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 1,515E-03 0,0143385 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 1,515E-03 0,01427973 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 1,515E-03 0,01422145 ! regulation of mitochondrial membrane potential GO:0051881 11 8 1,000 1,515E-03 0,01416364 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 1,515E-03 0,01410629 ! regulation of embryonic development GO:0045995 16 8 1,000 1,515E-03 0,01404941 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 1,515E-03 0,01399299 ! DNA damage checkpoint GO:0000077 53 31 2,000 1,585E-03 0,01458639 ! metanephros development GO:0001656 58 31 2,000 1,585E-03 0,01452827 ! leukocyte chemotaxis GO:0030595 43 31 2,000 1,585E-03 0,01447062 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 2,000 1,585E-03 0,01441343 ! positive regulation of phosphorylation GO:0042327 102 70 3,000 1,884E-03 0,01706143 ! cell junction organization GO:0034330 63 33 2,000 1,904E-03 0,01716934 ! androgen receptor signaling pathway GO:0030521 54 33 2,000 1,904E-03 0,01710227 ! positive regulation of DNA metabolic process GO:0051054 54 33 2,000 1,904E-03 0,01703573 ! negative regulation of DNA binding GO:0043392 54 33 2,000 1,904E-03 0,0169697 ! regulation of developmental growth GO:0048638 13 9 1,000 1,938E-03 0,01721155 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 1,938E-03 0,01714536 ! regulation of glycolysis GO:0006110 15 9 1,000 1,938E-03 0,01707966 ! lung alveolus development GO:0048286 17 9 1,000 1,938E-03 0,01701448 ! T cell selection GO:0045058 18 9 1,000 1,938E-03 0,01694978 ! alpha-beta T cell differentiation GO:0046632 14 9 1,000 1,938E-03 0,01688558 ! positive regulation of phagocytosis GO:0050766 11 9 1,000 1,938E-03 0,01682186 ! oocyte differentiation GO:0009994 12 9 1,000 1,938E-03 0,01675862 GO:0048599|oocyte development, ! spleen development GO:0048536 15 9 1,000 1,938E-03 0,01669585 ! sequestering of metal ion GO:0051238 11 9 1,000 1,938E-03 0,01663355 ! lymphocyte differentiation GO:0030098 113 71 3,000 1,985E-03 0,01697397 ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 2,076E-03 0,01768802 ! development of primary male sexual characteristics GO:0046546 44 34 2,000 2,076E-03 0,01762275 ! DNA integrity checkpoint GO:0031570 57 34 2,000 2,076E-03 0,01755796 ! erythrocyte homeostasis GO:0034101 45 34 2,000 2,076E-03 0,01749364 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 3,000 2,09E-03 0,01754333 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of transport GO:0051051 116 73 3,000 2,198E-03 0,01838687 ! pigment metabolic process GO:0042440 61 35 2,000 2,259E-03 0,01882282 ! protein homooligomerization GO:0051260 52 35 2,000 2,259E-03 0,01875487 ! cortical actin cytoskeleton organization GO:0030866 19 10 1,000 2,411E-03 0,01994581 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 2,411E-03 0,01987432 ! hair follicle morphogenesis GO:0031069 17 10 1,000 2,411E-03 0,01980334 ! blood vessel remodeling GO:0001974 21 10 1,000 2,411E-03 0,01973287 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 2,411E-03 0,0196629 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 2,411E-03 0,01959342 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 2,411E-03 0,01952442 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 2,411E-03 0,01945592 ! glucan biosynthetic process GO:0009250 13 10 1,000 2,411E-03 0,01938789 GO:0005978|glycogen biosynthetic process, ! response to X-ray GO:0010165 16 10 1,000 2,411E-03 0,01932034 ! B cell proliferation GO:0042100 14 10 1,000 2,411E-03 0,01925325 ! fear response GO:0042596 16 10 1,000 2,411E-03 0,01918663 ! negative regulation of ossification GO:0030279 19 10 1,000 2,411E-03 0,01912047 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 2,411E-03 0,01905476 ! regulation of bone resorption GO:0045124 24 10 1,000 2,411E-03 0,01898951 ! alpha-beta T cell activation GO:0046631 16 10 1,000 2,411E-03 0,0189247 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 2,411E-03 0,01886033 ! nitric oxide mediated signal transduction GO:0007263 17 10 1,000 2,411E-03 0,0187964 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 2,411E-03 0,01873289 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of immune effector process GO:0002698 16 10 1,000 2,411E-03 0,01866982 ! blood coagulation GO:0007596 116 75 3,000 2,427E-03 0,01873141 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 3,000 2,427E-03 0,01866877 ! response to reactive oxygen species GO:0000302 55 36 2,000 2,451E-03 0,01878861 ! negative regulation of binding GO:0051100 58 36 2,000 2,451E-03 0,01872619 ! regulation of DNA binding GO:0051101 119 77 3,000 2,671E-03 0,02034421 ! gland development GO:0048732 148 77 3,000 2,671E-03 0,02027707 ! sex differentiation GO:0007548 105 77 3,000 2,671E-03 0,02021037 ! positive regulation of protein modification process GO:0031401 107 78 3,000 2,8E-03 0,02111143 ! pigmentation GO:0043473 74 38 2,000 2,864E-03 0,02152793 ! T cell activation GO:0042110 134 79 3,000 2,932E-03 0,02196607 ! cortical cytoskeleton organization GO:0030865 20 11 1,000 2,932E-03 0,02189596 ! virus-host interaction GO:0019048 17 11 1,000 2,932E-03 0,0218251 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 2,932E-03 0,0217547 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 2,932E-03 0,02168475 ! regulation of intracellular pH GO:0051453 17 11 1,000 2,932E-03 0,02161524 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 2,932E-03 0,02154618 ! protein homotetramerization GO:0051289 18 11 1,000 2,932E-03 0,02147757 ! regulation of phagocytosis GO:0050764 14 11 1,000 2,932E-03 0,02140938 ! digestive tract morphogenesis GO:0048546 15 11 1,000 2,932E-03 0,02134163 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 2,932E-03 0,02127431 GO:0042130|negative regulation of T cell proliferation, ! male sex differentiation GO:0046661 53 39 2,000 3,086E-03 0,02232002 ! developmental growth GO:0048589 62 39 2,000 3,086E-03 0,02225005 ! cell growth GO:0016049 61 39 2,000 3,086E-03 0,02218052 ! hemostasis GO:0007599 125 81 3,000 3,21E-03 0,0229971 ! response to protein stimulus GO:0051789 111 81 3,000 3,21E-03 0,02292568 ! response to calcium ion GO:0051592 58 40 2,000 3,318E-03 0,02362731 ! B cell differentiation GO:0030183 62 40 2,000 3,318E-03 0,02355439 ! regulation of skeletal muscle fiber development GO:0048742 20 12 1,000 3,501E-03 0,02477889 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 3,501E-03 0,02470288 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 3,501E-03 0,02462734 ! gland morphogenesis GO:0022612 23 12 1,000 3,501E-03 0,02455225 ! peptidyl-lysine modification GO:0018205 18 12 1,000 3,501E-03 0,02447762 ! regulation of mRNA stability GO:0043488 27 12 1,000 3,501E-03 0,02440345 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 3,501E-03 0,02432972 ! regulation of cell adhesion GO:0030155 159 83 3,000 3,505E-03 0,0242789 ! mitochondrial transport GO:0006839 60 42 2,000 3,814E-03 0,02634108 ! cellular component disassembly GO:0022411 64 42 2,000 3,814E-03 0,02626222 ! negative regulation of multicellular organismal process GO:0051241 133 85 3,000 3,818E-03 0,02620998 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 4,078E-03 0,0279117 ! leukocyte migration GO:0050900 60 43 2,000 4,078E-03 0,02782888 ! activation of caspase activity GO:0006919 65 43 2,000 4,078E-03 0,02774654 ! vesicle organization GO:0016050 79 43 2,000 4,078E-03 0,02766469 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 4,118E-03 0,02785527 ! regulation of chemokine production GO:0032642 17 13 1,000 4,118E-03 0,02777358 ! negative regulation of mitotic cell cycle GO:0045930 23 13 1,000 4,118E-03 0,02769237 ! regulation of exocytosis GO:0017157 17 13 1,000 4,118E-03 0,02761164 ! regulation of cytokine production during immune response GO:0002718 18 13 1,000 4,118E-03 0,02753137 ! regulation of cellular pH GO:0030641 20 13 1,000 4,118E-03 0,02745157 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 4,118E-03 0,02737223 ! cellular pigmentation GO:0033059 24 13 1,000 4,118E-03 0,02729335 ! regulation of RNA stability GO:0043487 28 13 1,000 4,118E-03 0,02721492 ! regulation of cell projection organization GO:0031344 83 44 2,000 4,352E-03 0,02868197 ! negative regulation of cell migration GO:0030336 92 44 2,000 4,352E-03 0,02860003 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 4,352E-03 0,02851854 ! regulation of inflammatory response GO:0050727 60 44 2,000 4,352E-03 0,02843752 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 4,352E-03 0,02835697 ! regulation of neurogenesis GO:0050767 153 89 3,000 4,499E-03 0,02923194 ! positive regulation of defense response GO:0031349 59 45 2,000 4,638E-03 0,03004763 ! regulation of translational initiation GO:0006446 64 45 2,000 4,638E-03 0,02996323 ! regulation of skeletal muscle tissue development GO:0048641 22 14 1,000 4,781E-03 0,030799 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 4,781E-03 0,03071297 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 4,781E-03 0,03062742 ! epidermis morphogenesis GO:0048730 29 14 1,000 4,781E-03 0,03054234 ! cellular response to starvation GO:0009267 21 14 1,000 4,781E-03 0,03045773 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 4,781E-03 0,0303736 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 4,781E-03 0,03028992 ! G1/S transition checkpoint GO:0031575 33 14 1,000 4,781E-03 0,03020671 ! T cell differentiation in the thymus GO:0033077 27 14 1,000 4,781E-03 0,03012395 ! response to estrogen stimulus GO:0043627 74 47 2,000 5,242E-03 0,032944 ! negative regulation of immune system process GO:0002683 73 47 2,000 5,242E-03 0,03285424 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 5,242E-03 0,03276496 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 2,000 5,242E-03 0,03267616 ! metencephalon development GO:0022037 19 15 1,000 5,489E-03 0,03412117 ! lipid phosphorylation GO:0046834 23 15 1,000 5,489E-03 0,0340292 ! positive regulation of proteolysis GO:0045862 19 15 1,000 5,489E-03 0,03393773 ! regulation of survival gene product expression GO:0045884 20 15 1,000 5,489E-03 0,03384674 ! regulation of vasodilation GO:0042312 24 15 1,000 5,489E-03 0,03375624 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 5,489E-03 0,03366622 ! positive regulation of oxidoreductase activity GO:0051353 21 15 1,000 5,489E-03 0,03357669 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 5,489E-03 0,03348762 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 5,489E-03 0,03339903 ! defense response to virus GO:0051607 27 15 1,000 5,489E-03 0,03331091 ! positive regulation of caspase activity GO:0043280 72 48 2,000 5,562E-03 0,03366247 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 2,000 5,562E-03 0,03357412 ! regulation of response to external stimulus GO:0032101 139 96 3,000 5,881E-03 0,0354096 ! regulation of angiogenesis GO:0045765 94 49 2,000 5,892E-03 0,03538452 ! cartilage development GO:0051216 70 49 2,000 5,892E-03 0,03529237 ! regulation of multicellular organism growth GO:0040014 65 50 2,000 6,234E-03 0,03724504 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 2,000 6,234E-03 0,03714855 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 6,243E-03 0,03710059 ! protein amino acid acetylation GO:0006473 28 16 1,000 6,243E-03 0,03700497 ! cellular response to unfolded protein GO:0034620 19 16 1,000 6,243E-03 0,03690985 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of protein binding GO:0043393 27 16 1,000 6,243E-03 0,03681521 ! protein export from nucleus GO:0006611 24 16 1,000 6,243E-03 0,03672105 ! oogenesis GO:0048477 23 16 1,000 6,243E-03 0,03662737 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 6,243E-03 0,03653417 ! negative regulation of cell motion GO:0051271 104 51 2,000 6,588E-03 0,03845987 ! regulation of body fluid levels GO:0050878 154 100 3,000 6,785E-03 0,0395084 ! regulation of viral genome replication GO:0045069 24 17 1,000 7,04E-03 0,04089119 ! heme metabolic process GO:0042168 27 17 1,000 7,04E-03 0,04078819 ! long-chain fatty acid transport GO:0015909 24 17 1,000 7,04E-03 0,04068571 ! regulation of bone remodeling GO:0046850 90 53 2,000 7,331E-03 0,04226088 ! kidney development GO:0001822 90 53 2,000 7,331E-03 0,04215523 ! regulation of protein complex assembly GO:0043254 81 54 2,000 7,721E-03 0,0442832 ! regulation of tissue remodeling GO:0034103 91 54 2,000 7,721E-03 0,04417305 ! positive regulation of anti-apoptosis GO:0045768 29 18 1,000 7,882E-03 0,04498308 ! response to retinoic acid GO:0032526 25 18 1,000 7,882E-03 0,04487173 ! pigmentation during development GO:0048066 31 18 1,000 7,882E-03 0,04476094 ! somitogenesis GO:0001756 24 18 1,000 7,882E-03 0,04465069 ! synaptic vesicle transport GO:0048489 33 18 1,000 7,882E-03 0,04454098 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 7,882E-03 0,04443181 ! gut development GO:0048565 26 18 1,000 7,882E-03 0,04432318 ! negative regulation of T cell activation GO:0050868 25 18 1,000 7,882E-03 0,04421507 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 7,882E-03 0,0441075 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 8,535E-03 0,04764935 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 8,766E-03 0,04881877 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 8,766E-03 0,04870085 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 8,766E-03 0,0485835 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 8,766E-03 0,04846671 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regeneration GO:0031099 32 19 1,000 8,766E-03 0,04835048 ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 8,766E-03 0,04823481 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 8,766E-03 0,04811969 ! response to vitamin A GO:0033189 26 19 1,000 8,766E-03 0,04800512 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 8,766E-03 0,0478911 ! apoptotic nuclear changes GO:0030262 24 19 1,000 8,766E-03 0,04777761 ! response to starvation GO:0042594 30 19 1,000 8,766E-03 0,04766466 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 8,766E-03 0,04755225 ! renal system process GO:0003014 35 19 1,000 8,766E-03 0,04744036 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 8,766E-03 0,047329 ! protein stabilization GO:0050821 26 19 1,000 8,766E-03 0,04721815 ! developmental maturation GO:0021700 75 57 2,000 8,961E-03 0,04815512 ! gonad development GO:0008406 79 57 2,000 8,961E-03 0,04804287 ! response to vitamin GO:0033273 29 20 1,000 9,693E-03 0,0518448 ! response to ethanol GO:0045471 37 20 1,000 9,693E-03 0,05172451 ! multicellular organismal response to stress GO:0033555 32 20 1,000 9,693E-03 0,05160477 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 9,693E-03 0,05148559 ! positive regulation of B cell activation GO:0050871 31 20 1,000 9,693E-03 0,05136696 ! lung development GO:0030324 94 59 2,000 9,849E-03 0,05207515 ! regulation of heart contraction GO:0008016 91 60 2,000 0,0103115 0,05439552 ! regulation of vesicle-mediated transport GO:0060627 79 60 2,000 0,0103115 0,05427105 ! regulation of homeostatic process GO:0032844 105 60 2,000 0,0103115 0,05414714 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 0,01066085 0,05585413 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 1,000 0,01066085 0,05572719 ! protein amino acid acylation GO:0043543 37 21 1,000 0,01066085 0,05560082 ! ovarian follicle development GO:0001541 30 21 1,000 0,01066085 0,05547503 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 0,01066085 0,05534981 ! fatty acid transport GO:0015908 30 21 1,000 0,01066085 0,05522514 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 0,01066085 0,05510104 ! response to cytokine stimulus GO:0034097 47 21 1,000 0,01066085 0,0549775 ! porphyrin metabolic process GO:0006778 35 21 1,000 0,01066085 0,0548545 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 1,000 0,01066085 0,05473206 ! respiratory tube development GO:0030323 99 62 2,000 0,01127386 0,0577503 ! macromolecular complex disassembly GO:0032984 38 22 1,000 0,01166988 0,05964606 ! regulation of anti-apoptosis GO:0045767 36 22 1,000 0,01166988 0,05951381 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 0,01166988 0,05938214 ! ureteric bud development GO:0001657 32 22 1,000 0,01166988 0,05925105 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 2,000 0,01177384 0,05964719 ! respiratory system development GO:0060541 100 64 2,000 0,01228641 0,06210712 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01271915 0,0641536 ! negative regulation of DNA replication GO:0008156 35 23 1,000 0,01271915 0,06401322 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 0,01271915 0,06387345 ! regulation of viral reproduction GO:0050792 32 23 1,000 0,01271915 0,06373429 ! interaction with host GO:0051701 37 23 1,000 0,01271915 0,06359574 ! lymphocyte proliferation GO:0046651 36 23 1,000 0,01271915 0,06345779 ! cellular response to oxidative stress GO:0034599 33 23 1,000 0,01271915 0,06332043 ! liver development GO:0001889 40 23 1,000 0,01271915 0,06318367 ! regulation of caspase activity GO:0043281 97 65 2,000 0,01281163 0,06350591 ! B cell activation GO:0042113 104 65 2,000 0,01281163 0,06336934 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 0,013808 0,06815109 ! fat cell differentiation GO:0045444 37 24 1,000 0,013808 0,06800516 ! response to toxin GO:0009636 38 24 1,000 0,013808 0,06785985 ! negative regulation of cell development GO:0010721 56 24 1,000 0,013808 0,06771515 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 0,013808 0,06757108 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 0,013808 0,06742762 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 0,01390018 0,06773393 ! regulation of neuron differentiation GO:0045664 107 67 2,000 0,01390018 0,06759073 ! learning or memory GO:0007611 123 68 2,000 0,01446359 0,070182 ! development of primary sexual characteristics GO:0045137 92 68 2,000 0,01446359 0,07003424 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 1,000 0,0149358 0,0721688 ! iron ion homeostasis GO:0055072 39 25 1,000 0,0149358 0,07201751 ! regulation of chromosome organization GO:0033044 35 25 1,000 0,0149358 0,07186684 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,0149358 0,07171681 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 1,000 0,0149358 0,0715674 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 0,0149358 0,07141861 ! response to drug GO:0042493 108 69 2,000 0,01503981 0,07176675 ! regulation of catabolic process GO:0009894 106 70 2,000 0,01562887 0,0744232 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 0,01610192 0,07651737 ! regulation of pH GO:0006885 36 26 1,000 0,01610192 0,0763596 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 0,01610192 0,07620249 ! post-embryonic development GO:0009791 42 26 1,000 0,01610192 0,07604601 ! regulation of peptidase activity GO:0052547 106 72 2,000 0,01684562 0,07939533 ! negative regulation of organelle organization GO:0010639 115 72 2,000 0,01684562 0,07923297 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 1,000 0,01730571 0,08123089 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 1,000 0,01730571 0,08106545 ! cofactor catabolic process GO:0051187 45 27 1,000 0,01730571 0,08090068 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 0,01730571 0,08073658 ! response to steroid hormone stimulus GO:0048545 114 73 2,000 0,01747335 0,08135367 ! protein import into nucleus GO:0006606 118 74 2,000 0,01811403 0,08416619 ! positive regulation of endocytosis GO:0045807 33 28 1,000 0,01854657 0,08600222 ! triglyceride metabolic process GO:0006641 34 28 1,000 0,01854657 0,08582918 ! erythrocyte differentiation GO:0030218 38 28 1,000 0,01854657 0,08565683 ! myeloid leukocyte activation GO:0002274 39 28 1,000 0,01854657 0,08548517 ! nuclear import GO:0051170 121 75 2,000 0,01876766 0,08633122 ! amine biosynthetic process GO:0009309 97 76 2,000 0,01943426 0,08921914 ! response to unfolded protein GO:0006986 99 76 2,000 0,01943426 0,08904141 ! ovulation cycle process GO:0022602 41 29 1,000 0,01982387 0,09064591 ! tissue homeostasis GO:0001894 42 29 1,000 0,01982387 0,09046606 GO:0048871|multicellular organismal homeostasis, ! cholesterol transport GO:0030301 46 30 1,000 0,02113701 0,09626757 GO:0015918|sterol transport, ! spindle organization GO:0007051 37 30 1,000 0,02113701 0,09607732 ! ovulation cycle GO:0042698 43 30 1,000 0,02113701 0,09588781 ! hindbrain development GO:0030902 45 30 1,000 0,02113701 0,09569906 ! protein localization in nucleus GO:0034504 133 80 2,000 0,02223055 0,10045237 ! negative regulation of secretion GO:0051048 49 31 1,000 0,02248539 0,1014047 ! segmentation GO:0035282 41 31 1,000 0,02248539 0,10120626 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,02248539 0,10100859 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,02248539 0,10081169 ! regulation of muscle development GO:0048634 48 32 1,000 0,02386842 0,10680421 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,02386842 0,10659682 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,02386842 0,10639024 ! meiosis I GO:0007127 52 32 1,000 0,02386842 0,10618446 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 0,02386842 0,10597947 ! neutral lipid metabolic process GO:0006638 41 32 1,000 0,02386842 0,10577527 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,02386842 0,10557185 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,02386842 0,10536922 ! biogenic amine metabolic process GO:0006576 121 83 2,000 0,02446428 0,1077928 ! regulation of defense response GO:0031347 117 84 2,000 0,02523485 0,11097545 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,02523485 0,11076366 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,02528551 0,1107746 ! sister chromatid segregation GO:0000819 46 33 1,000 0,02528551 0,110564 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 1,000 0,02528551 0,1103542 ! carbohydrate homeostasis GO:0033500 39 33 1,000 0,02528551 0,1101452 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 1,000 0,02528551 0,10993699 ! female gonad development GO:0008585 49 33 1,000 0,02528551 0,10972956 ! positive regulation of cell development GO:0010720 54 33 1,000 0,02528551 0,10952291 ! regulation of proteolysis GO:0030162 50 33 1,000 0,02528551 0,10931704 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,02528551 0,10911194 ! cytokinesis GO:0000910 52 33 1,000 0,02528551 0,10890761 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 0,02601841 0,11185485 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 0,02601841 0,11164617 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,02673607 0,11451205 ! glycerol ether metabolic process GO:0006662 44 34 1,000 0,02673607 0,1142992 ! female gamete generation GO:0007292 43 34 1,000 0,02673607 0,11408715 ! polysaccharide biosynthetic process GO:0000271 47 35 1,000 0,02821955 0,12019438 ! glycogen metabolic process GO:0005977 48 35 1,000 0,02821955 0,11997221 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,02821955 0,11975086 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,02973536 0,1259509 GO:0090047|positive regulation of transcription regulator activity, ! organic ether metabolic process GO:0018904 46 36 1,000 0,02973536 0,12571937 ! tissue remodeling GO:0048771 62 36 1,000 0,02973536 0,1254887 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,02973536 0,12525886 GO:0046660|female sex differentiation, ! glucan metabolic process GO:0044042 49 36 1,000 0,02973536 0,12502987 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 67 37 1,000 0,03128296 0,1312971 ! cell fate commitment GO:0045165 141 92 2,000 0,03186585 0,13349992 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,03286178 0,137422 ! monocarboxylic acid transport GO:0015718 62 38 1,000 0,03286178 0,1371726 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,03286178 0,1369241 ! phagocytosis GO:0006909 60 38 1,000 0,03286178 0,1366765 ! mesenchymal cell development GO:0014031 64 38 1,000 0,03286178 0,13642979 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! response to oxidative stress GO:0006979 141 94 2,000 0,0336525 0,13946081 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,03447129 0,14259705 ! JNK cascade GO:0007254 54 39 1,000 0,03447129 0,14234104 ! angiogenesis GO:0001525 149 95 2,000 0,03456503 0,14247234 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 0,03549032 0,14602456 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 0,03611093 0,14831274 ! double-strand break repair GO:0006302 67 40 1,000 0,03611093 0,14804837 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,03611093 0,14778494 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 2,000 0,03642834 0,14881913 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03691395 0,1505356 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03691395 0,15026917 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03691395 0,15000367 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03691395 0,14973912 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03691395 0,14947549 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03691395 0,14921279 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03691395 0,14895102 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03691395 0,14869016 ! sleep GO:0030431 11 5 0,000 0,03691395 0,14843021 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03691395 0,14817117 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03691395 0,14791303 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03691395 0,14765579 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03691395 0,14739944 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03691395 0,14714398 ! tongue development GO:0043586 6 5 0,000 0,03691395 0,14688941 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03691395 0,14663571 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03691395 0,14638289 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03691395 0,14613094 ! cobalt ion transport GO:0006824 9 5 0,000 0,03691395 0,14587986 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03691395 0,14562964 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03691395 0,14538027 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03691395 0,14513176 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03691395 0,14488409 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03691395 0,14463727 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03691395 0,14439129 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03691395 0,14414614 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03691395 0,14390183 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03691395 0,14365834 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03691395 0,14341567 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03691395 0,14317383 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03691395 0,14293279 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03691395 0,14269257 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03691395 0,14245315 ! malate metabolic process GO:0006108 7 5 0,000 0,03691395 0,14221454 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03691395 0,14197672 ! behavioral response to pain GO:0048266 7 5 0,000 0,03691395 0,1417397 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03691395 0,14150346 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03691395 0,14126802 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03691395 0,14103335 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03691395 0,14079947 ! mating behavior GO:0007617 6 5 0,000 0,03691395 0,14056636 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03691395 0,14033401 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03691395 0,14010244 ! rhythmic behavior GO:0007622 12 5 0,000 0,03691395 0,13987163 ! copulation GO:0007620 7 5 0,000 0,03691395 0,13964158 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03691395 0,13941228 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,03691395 0,13918374 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03691395 0,13895594 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03691395 0,13872889 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03691395 0,13850258 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03691395 0,138277 ! response to protozoan GO:0001562 9 5 0,000 0,03691395 0,13805216 ! lymph vessel development GO:0001945 7 5 0,000 0,03691395 0,13782805 ! endochondral ossification GO:0001958 12 5 0,000 0,03691395 0,13760467 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03691395 0,137382 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03691395 0,13716006 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03691395 0,13693884 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03691395 0,13671832 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03691395 0,13649852 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03691395 0,13627942 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03691395 0,13606102 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03691395 0,13584333 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03691395 0,13562632 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03691395 0,13541001 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,03691395 0,13519439 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03691395 0,13497946 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03691395 0,1347652 ! ovulation GO:0030728 6 5 0,000 0,03691395 0,13455163 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03691395 0,13433873 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,03691395 0,13412651 ! response to pH GO:0009268 9 5 0,000 0,03691395 0,13391495 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03691395 0,13370406 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03691395 0,13349383 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03691395 0,13328427 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03691395 0,13307536 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03691395 0,1328671 ! polyol catabolic process GO:0046174 7 5 0,000 0,03691395 0,1326595 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03691395 0,13245254 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03691395 0,13224623 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03691395 0,13204056 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03691395 0,13183553 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03691395 0,13163113 ! urea metabolic process GO:0019627 6 5 0,000 0,03691395 0,13142737 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03691395 0,13122423 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03691395 0,13102173 ! neutrophil activation GO:0042119 5 5 0,000 0,03691395 0,13081984 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03691395 0,13061858 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03691395 0,13041794 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03691395 0,13021791 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03691395 0,1300185 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03691395 0,12981969 ! forebrain neuron development GO:0021884 7 5 0,000 0,03691395 0,12962149 ! melanosome organization GO:0032438 7 5 0,000 0,03691395 0,1294239 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03691395 0,12922691 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03691395 0,12903051 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03691395 0,12883472 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,03691395 0,12863951 ! nucleoside transport GO:0015858 6 5 0,000 0,03691395 0,1284449 ! nucleoside salvage GO:0043174 7 5 0,000 0,03691395 0,12825087 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03691395 0,12805743 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03691395 0,12786458 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03691395 0,1276723 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03691395 0,1274806 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03691395 0,12728947 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,03691395 0,12709892 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03691395 0,12690894 ! depyrimidination GO:0045008 8 5 0,000 0,03691395 0,12671952 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03691395 0,12653067 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03691395 0,12634238 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03691395 0,12615465 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03691395 0,12596748 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03691395 0,12578086 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03691395 0,12559479 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03691395 0,12540927 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03691395 0,1252243 ! monocyte differentiation GO:0030224 8 5 0,000 0,03691395 0,12503988 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03691395 0,124856 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03691395 0,12467266 ! centrosome duplication GO:0051298 5 5 0,000 0,03691395 0,12448985 ! response to UV-C GO:0010225 6 5 0,000 0,03691395 0,12430758 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03691395 0,12412585 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03691395 0,12394464 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03691395 0,12376396 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03691395 0,12358381 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03691395 0,12340418 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03691395 0,12322508 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03691395 0,12304649 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03691395 0,12286842 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03691395 0,12269087 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03691395 0,12251382 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03691395 0,12233729 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,03691395 0,12216126 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03691395 0,12198575 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03691395 0,12181073 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03691395 0,12163622 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03691395 0,1214622 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03691395 0,12128868 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03691395 0,12111566 ! neural tube patterning GO:0021532 6 5 0,000 0,03691395 0,12094313 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03691395 0,12077109 ! histone demethylation GO:0016577 9 5 0,000 0,03691395 0,12059954 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03691395 0,12042848 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,03691395 0,1202579 ! enteric nervous system development GO:0048484 8 5 0,000 0,03691395 0,12008781 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03691395 0,11991819 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03691395 0,11974905 ! muscle cell proliferation GO:0033002 8 5 0,000 0,03691395 0,11958039 ! transcription termination GO:0006353 8 5 0,000 0,03691395 0,11941221 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03691395 0,11924449 ! plasminogen activation GO:0031639 5 5 0,000 0,03691395 0,11907725 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03691395 0,11891047 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03691395 0,11874417 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03691395 0,11857832 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,03691395 0,11841294 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,03691395 0,11824802 ! apical protein localization GO:0045176 6 5 0,000 0,03691395 0,11808356 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,03691395 0,11791955 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03691395 0,117756 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03691395 0,11759291 GO:0006681|galactosylceramide metabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03691395 0,11743026 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03691395 0,11726806 ! glial cell migration GO:0008347 10 5 0,000 0,03691395 0,11710632 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03691395 0,11694501 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03691395 0,11678415 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03691395 0,11662373 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03691395 0,11646376 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03691395 0,11630422 ! neural plate development GO:0001840 6 5 0,000 0,03691395 0,11614511 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03691395 0,11598645 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03691395 0,11582821 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03691395 0,11567041 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03691395 0,11551303 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03691395 0,11535609 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03691395 0,11519956 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03691395 0,11504347 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03691395 0,11488779 ! spindle assembly GO:0051225 5 5 0,000 0,03691395 0,11473254 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03691395 0,1145777 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03691395 0,11442329 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03691395 0,11426928 ! organ regeneration GO:0031100 7 5 0,000 0,03691395 0,1141157 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03691395 0,11396252 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03691395 0,11380976 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03691395 0,1136574 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03691395 0,11350545 GO:0055081|anion homeostasis, ! epithelial cell differentiation GO:0030855 55 41 1,000 0,03778017 0,11601388 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,03778017 0,1158592 ! glucose transport GO:0015758 52 41 1,000 0,03778017 0,11570493 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,03778017 0,11555106 ! regulation of leukocyte mediated immunity GO:0002703 62 41 1,000 0,03778017 0,11539761 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,03778017 0,11524456 ! protein import GO:0017038 156 99 2,000 0,03834243 0,11680474 ! protein localization in organelle GO:0033365 161 100 2,000 0,03931842 0,11961954 ! hexose transport GO:0008645 54 42 1,000 0,0394785 0,11994787 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 1,000 0,0394785 0,11978963 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 1,000 0,0394785 0,11963181 ! excretion GO:0007588 63 42 1,000 0,0394785 0,1194744 ! regulation of cell shape GO:0008360 78 42 1,000 0,0394785 0,1193174 ! positive regulation of binding GO:0051099 59 43 1,000 0,04120537 0,12437317 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,04120537 0,12421016 ! tRNA transcription GO:0009304 11 6 0,000 0,04413282 0,13286059 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04413282 0,13268692 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,04413282 0,1325137 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04413282 0,13234093 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04413282 0,13216861 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04413282 0,13199674 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04413282 0,13182531 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,04413282 0,13165433 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04413282 0,1314838 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04413282 0,1313137 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04413282 0,13114404 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04413282 0,13097483 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04413282 0,13080604 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04413282 0,1306377 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,04413282 0,13046978 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04413282 0,1303023 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04413282 0,13013524 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04413282 0,12996862 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04413282 0,12980242 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04413282 0,12963664 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,04413282 0,12947129 ! neuron adhesion GO:0007158 9 6 0,000 0,04413282 0,12930636 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04413282 0,12914185 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04413282 0,12897775 ! signal peptide processing GO:0006465 8 6 0,000 0,04413282 0,12881407 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04413282 0,12865081 ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04413282 0,12848796 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04413282 0,12832553 ! opsonization GO:0008228 8 6 0,000 0,04413282 0,1281635 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04413282 0,12800188 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04413282 0,12784067 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04413282 0,12767986 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04413282 0,12751946 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04413282 0,12735946 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04413282 0,12719986 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04413282 0,12704066 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04413282 0,12688186 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04413282 0,12672346 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04413282 0,12656545 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04413282 0,12640783 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04413282 0,12625061 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04413282 0,12609378 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04413282 0,12593733 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04413282 0,12578128 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04413282 0,12562561 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04413282 0,12547032 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04413282 0,12531542 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04413282 0,1251609 ! thymic T cell selection GO:0045061 12 6 0,000 0,04413282 0,12500676 ! protein lipoylation GO:0009249 10 6 0,000 0,04413282 0,124853 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04413282 0,12469962 ! drug transport GO:0015893 6 6 0,000 0,04413282 0,12454661 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04413282 0,12439398 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04413282 0,12424173 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04413282 0,12408984 ! histidine metabolic process GO:0006547 6 6 0,000 0,04413282 0,12393833 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04413282 0,12378718 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04413282 0,12363641 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,04413282 0,123486 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,04413282 0,12333595 ! adenohypophysis development GO:0021984 10 6 0,000 0,04413282 0,12318627 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04413282 0,12303696 ! hyperosmotic response GO:0006972 8 6 0,000 0,04413282 0,122888 ! microtubule nucleation GO:0007020 10 6 0,000 0,04413282 0,12273941 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04413282 0,12259117 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04413282 0,12244329 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04413282 0,12229577 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04413282 0,1221486 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04413282 0,12200179 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,04413282 0,12185533 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04413282 0,12170922 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,04413282 0,12156346 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04413282 0,12141805 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04413282 0,12127299 ! purine salvage GO:0043101 8 6 0,000 0,04413282 0,12112827 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04413282 0,1209839 ! neuron apoptosis GO:0051402 8 6 0,000 0,04413282 0,12083987 ! organic alcohol transport GO:0015850 9 6 0,000 0,04413282 0,12069618 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04413282 0,12055284 ! carnitine transport GO:0015879 8 6 0,000 0,04413282 0,12040983 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04413282 0,12026717 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04413282 0,12012484 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04413282 0,11998285 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04413282 0,11984119 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04413282 0,11969987 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04413282 0,11955888 ! parturition GO:0007567 12 6 0,000 0,04413282 0,11941822 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04413282 0,1192779 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04413282 0,1191379 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,04413282 0,11899823 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,04413282 0,11885889 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,04413282 0,11871987 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04413282 0,11858118 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04413282 0,11844281 ! astrocyte development GO:0014002 14 6 0,000 0,04413282 0,11830477 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04413282 0,11816704 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04413282 0,11802964 ! interaction with symbiont GO:0051702 8 6 0,000 0,04413282 0,11789256 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04413282 0,11775579 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04413282 0,11761934 ! eating behavior GO:0042755 6 6 0,000 0,04413282 0,11748321 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04413282 0,11734739 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04413282 0,11721188 ! response to copper ion GO:0046688 9 6 0,000 0,04413282 0,11707669 ! DNA topological change GO:0006265 8 6 0,000 0,04413282 0,11694181 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04413282 0,11680724 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04413282 0,11667298 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04413282 0,11653902 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04413282 0,11640538 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04413282 0,11627204 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04413282 0,11613901 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04413282 0,11600627 ! gas homeostasis GO:0033483 11 6 0,000 0,04413282 0,11587385 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04413282 0,11574172 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04413282 0,1156099 ! Schwann cell development GO:0014044 14 6 0,000 0,04413282 0,11547837 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04413282 0,11534715 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04413282 0,11521622 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04413282 0,11508559 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04413282 0,11495526 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04413282 0,11482522 ! histone ubiquitination GO:0016574 7 6 0,000 0,04413282 0,11469547 ! G2 phase GO:0051319 13 6 0,000 0,04413282 0,11456602 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04413282 0,11443686 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04413282 0,11430798 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04413282 0,1141794 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04413282 0,11405111 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04413282 0,11392311 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04413282 0,11379539 ! receptor internalization GO:0031623 9 6 0,000 0,04413282 0,11366796 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,04413282 0,11354082 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04413282 0,11341396 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04413282 0,11328738 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,04413282 0,11316108 ! protein deubiquitination GO:0016579 8 6 0,000 0,04413282 0,11303507 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04413282 0,11290933 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,04413282 0,11278388 ! axonal fasciculation GO:0007413 9 6 0,000 0,04413282 0,1126587 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04413282 0,1125338 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04413282 0,11240918 ! midbrain development GO:0030901 6 6 0,000 0,04413282 0,11228483 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04413282 0,11216076 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04413282 0,11203697 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04413282 0,11191344 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04413282 0,11179019 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04413282 0,11166721 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04413282 0,1115445 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04413282 0,11142205 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04413282 0,11129988 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04413282 0,11117797 ! adult feeding behavior GO:0008343 6 6 0,000 0,04413282 0,11105634 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04413282 0,11093496 ! blastocyst growth GO:0001832 15 6 0,000 0,04413282 0,11081385 ! pigment granule transport GO:0051904 12 6 0,000 0,04413282 0,11069301 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04413282 0,11057243 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04413282 0,11045211 ! catecholamine transport GO:0051937 7 6 0,000 0,04413282 0,11033205 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04413282 0,11021226 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04413282 0,11009272 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04413282 0,10997345 ! protein prenylation GO:0018342 10 6 0,000 0,04413282 0,10985443 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04413282 0,10973567 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04413282 0,10961716 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04413282 0,10949891 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04413282 0,10938092 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,04474273 0,11077317 ! regulation of ossification GO:0030278 71 46 1,000 0,04655219 0,11512908 ! histone modification GO:0016570 68 46 1,000 0,04655219 0,11500542 ! endocrine system development GO:0035270 83 47 1,000 0,04838818 0,1194129 ! covalent chromatin modification GO:0016569 75 47 1,000 0,04838818 0,11928491 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,05025021 0,12374248 ! heart morphogenesis GO:0003007 65 48 1,000 0,05025021 0,12361014 ! regulation of endocytosis GO:0030100 63 48 1,000 0,05025021 0,12347808 ! nuclear export GO:0051168 69 48 1,000 0,05025021 0,1233463 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,05025021 0,1232148 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,051298 0,12565005 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,051298 0,12551638 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,051298 0,12538299 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,051298 0,12524989 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,051298 0,12511707 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,051298 0,12498453 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,051298 0,12485227 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,051298 0,12472029 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,051298 0,12458859 ! reproductive behavior GO:0019098 12 7 0,000 0,051298 0,12445717 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,051298 0,12432602 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,051298 0,12419515 ! oligopeptide transport GO:0006857 11 7 0,000 0,051298 0,12406456 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,051298 0,12393424 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,051298 0,12380419 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,051298 0,12367442 ! RNA methylation GO:0001510 11 7 0,000 0,051298 0,12354491 ! pericardium development GO:0060039 8 7 0,000 0,051298 0,12341568 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,051298 0,12328672 ! fibril organization GO:0043206 13 7 0,000 0,051298 0,12315803 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,051298 0,12302961 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,051298 0,12290145 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,051298 0,12277356 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,051298 0,12264594 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,051298 0,12251858 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,051298 0,12239149 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,051298 0,12226466 ! estrogen metabolic process GO:0008210 14 7 0,000 0,051298 0,12213809 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,051298 0,12201178 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,051298 0,12188574 ! chemosensory behavior GO:0007635 9 7 0,000 0,051298 0,12175995 ! microtubule bundle formation GO:0001578 8 7 0,000 0,051298 0,12163443 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,051298 0,12150916 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,051298 0,12138415 ! leukocyte degranulation GO:0043299 10 7 0,000 0,051298 0,1212594 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,051298 0,1211349 ! reflex GO:0060004 12 7 0,000 0,051298 0,12101066 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,051298 0,12088667 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,051298 0,12076294 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,051298 0,12063946 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,051298 0,12051623 ! spinal cord patterning GO:0021511 7 7 0,000 0,051298 0,12039326 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,051298 0,12027053 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,051298 0,12014806 ! adrenal gland development GO:0030325 17 7 0,000 0,051298 0,12002583 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,051298 0,11990385 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,051298 0,11978213 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,051298 0,11966064 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,051298 0,11953941 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,051298 0,11941841 ! endosome organization GO:0007032 10 7 0,000 0,051298 0,11929767 ! thyroid hormone generation GO:0006590 11 7 0,000 0,051298 0,11917716 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,051298 0,11905691 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,051298 0,11893689 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,051298 0,11881711 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,051298 0,11869758 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,051298 0,11857828 ! galactose metabolic process GO:0006012 10 7 0,000 0,051298 0,11845923 ! vesicle fusion GO:0006906 15 7 0,000 0,051298 0,11834041 ! intracellular pH reduction GO:0051452 10 7 0,000 0,051298 0,11822184 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,051298 0,1181035 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,051298 0,11798539 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,051298 0,11786753 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,051298 0,11774989 ! retinol metabolic process GO:0042572 9 7 0,000 0,051298 0,1176325 ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,051298 0,11751533 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,051298 0,1173984 ! rRNA modification GO:0000154 12 7 0,000 0,051298 0,1172817 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,051298 0,11716524 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,051298 0,117049 ! intermediate filament organization GO:0045109 11 7 0,000 0,051298 0,116933 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,051298 0,11681722 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,051298 0,11670167 ! fibrinolysis GO:0042730 9 7 0,000 0,051298 0,11658636 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,051298 0,11647127 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,051298 0,1163564 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,051298 0,11624177 ! response to tropane GO:0014073 13 7 0,000 0,051298 0,11612736 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,051298 0,11601317 ! melanosome localization GO:0032400 10 7 0,000 0,051298 0,11589921 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,051298 0,11578547 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,051298 0,11567195 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,051298 0,11555866 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,051298 0,11544559 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,051298 0,11533274 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,051298 0,11522011 ! multicellular organismal aging GO:0010259 11 7 0,000 0,051298 0,1151077 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,051298 0,11499551 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,051298 0,11488354 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,051298 0,11477178 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,051298 0,11466025 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,051298 0,11454893 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,051298 0,11443782 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,051298 0,11432693 ! regulation of lipid transport GO:0032368 13 7 0,000 0,051298 0,11421626 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,051298 0,1141058 ! neuroblast proliferation GO:0007405 13 7 0,000 0,051298 0,11399555 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,051298 0,11388551 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,051298 0,11377569 ! diuresis GO:0030146 12 7 0,000 0,051298 0,11366608 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,051298 0,11355668 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,051298 0,11344749 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,051298 0,11333851 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,051298 0,11322974 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,051298 0,11312118 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,051298 0,11301283 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,051298 0,11290468 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,051298 0,11279674 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,051298 0,11268901 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,051298 0,11258148 ! lymph node development GO:0048535 9 7 0,000 0,051298 0,11247416 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,051298 0,11236704 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,051298 0,11226013 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,051298 0,11215342 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,051298 0,11204691 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,051298 0,1119406 ! ATP catabolic process GO:0006200 10 7 0,000 0,051298 0,1118345 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,051298 0,11172859 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,051298 0,11162289 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,051298 0,11151738 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,051298 0,11141208 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,051298 0,11130697 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,051298 0,11120207 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,051298 0,11109736 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,051298 0,11099284 ! retina homeostasis GO:0001895 9 7 0,000 0,051298 0,11088853 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,051298 0,11078441 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,051298 0,11068048 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,051298 0,11057675 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,051298 0,11047321 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,051298 0,11036987 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,051298 0,11026672 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,051298 0,11016377 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,05213778 0,11186277 ! heterocycle catabolic process GO:0046700 72 49 1,000 0,05213778 0,11175852 ! maintenance of location GO:0051235 84 49 1,000 0,05213778 0,11165446 ! ear development GO:0043583 72 50 1,000 0,05405042 0,11564275 ! lipid modification GO:0030258 73 50 1,000 0,05405042 0,11553528 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,05598764 0,11956507 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,05598764 0,11945416 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,05794899 0,12352427 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,05840987 0,12439139 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,05840987 0,12427632 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,05840987 0,12416146 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,05840987 0,12404681 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,05840987 0,12393238 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,05840987 0,12381816 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,05840987 0,12370414 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,05840987 0,12359034 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,05840987 0,12347675 ! phosphate transport GO:0006817 10 8 0,000 0,05840987 0,12336336 ! N-glycan processing GO:0006491 12 8 0,000 0,05840987 0,12325018 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,05840987 0,12313721 ! UTP metabolic process GO:0046051 8 8 0,000 0,05840987 0,12302445 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,05840987 0,12291189 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,05840987 0,12279954 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,05840987 0,1226874 ! succinate metabolic process GO:0006105 14 8 0,000 0,05840987 0,12257546 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,05840987 0,12246372 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,05840987 0,12235218 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05840987 0,12224085 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,05840987 0,12212973 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,05840987 0,1220188 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,05840987 0,12190808 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,05840987 0,12179755 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,05840987 0,12168723 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05840987 0,1215771 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,05840987 0,12146718 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,05840987 0,12135745 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,05840987 0,12124792 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,05840987 0,12113859 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,05840987 0,12102946 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,05840987 0,12092052 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,05840987 0,12081178 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,05840987 0,12070323 ! astrocyte differentiation GO:0048708 16 8 0,000 0,05840987 0,12059488 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,05840987 0,12048673 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,05840987 0,12037876 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,05840987 0,12027099 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,05840987 0,12016342 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,05840987 0,12005603 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,05840987 0,11994884 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05840987 0,11984184 ! macrophage activation GO:0042116 12 8 0,000 0,05840987 0,11973503 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,05840987 0,1196284 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,05840987 0,11952197 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,05840987 0,11941573 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,05840987 0,11930968 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,05840987 0,11920381 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,05840987 0,11909814 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,05840987 0,11899265 ! ruffle organization GO:0031529 11 8 0,000 0,05840987 0,11888734 ! osteoblast development GO:0002076 13 8 0,000 0,05840987 0,11878223 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,05840987 0,1186773 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,05840987 0,11857255 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,05840987 0,11846799 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,05840987 0,11836361 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,05840987 0,11825942 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,05840987 0,11815541 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,05840987 0,11805158 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,05840987 0,11794794 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,05840987 0,11784447 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,05840987 0,11774119 ! oligodendrocyte development GO:0014003 8 8 0,000 0,05840987 0,11763809 ! segment specification GO:0007379 10 8 0,000 0,05840987 0,11753517 ! cellular extravasation GO:0045123 11 8 0,000 0,05840987 0,11743243 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,05840987 0,11732987 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,05840987 0,11722749 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,05840987 0,11712528 ! snRNA metabolic process GO:0016073 10 8 0,000 0,05840987 0,11702326 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,05840987 0,11692141 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,05840987 0,11681974 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,05840987 0,11671824 ! nucleosome disassembly GO:0006337 12 8 0,000 0,05840987 0,11661693 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,05840987 0,11651578 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,05840987 0,11641482 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,05840987 0,11631402 ! icosanoid secretion GO:0032309 12 8 0,000 0,05840987 0,11621341 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,05840987 0,11611296 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05840987 0,11601269 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,05840987 0,1159126 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,05840987 0,11581267 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,05840987 0,11571292 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,05840987 0,11561334 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,05840987 0,11551393 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,05840987 0,11541469 ! sterol catabolic process GO:0016127 9 8 0,000 0,05840987 0,11531562 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,05840987 0,11521672 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,05840987 0,11511799 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,05840987 0,11501943 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,05840987 0,11492104 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05840987 0,11482282 ! prophase GO:0051324 11 8 0,000 0,05840987 0,11472476 ! S phase GO:0051320 8 8 0,000 0,05840987 0,11462688 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,05840987 0,11452915 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,05840987 0,1144316 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,05840987 0,11433421 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,05840987 0,11423699 ! hormone catabolic process GO:0042447 13 8 0,000 0,05840987 0,11413993 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,05840987 0,11404304 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,05840987 0,11394631 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,05840987 0,11384974 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,05840987 0,11375334 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,05840987 0,11365711 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,05840987 0,11356103 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,05840987 0,11346512 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05840987 0,11336937 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,05840987 0,11327378 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,05840987 0,11317835 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,05840987 0,11308308 ! lamellipodium assembly GO:0030032 9 8 0,000 0,05840987 0,11298797 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05840987 0,11289302 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,05840987 0,11279824 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,0619422 0,11951935 ! DNA catabolic process GO:0006308 67 54 1,000 0,0619422 0,11941917 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,06546883 0,12611249 ! telencephalon cell migration GO:0022029 16 9 0,000 0,06546883 0,12600696 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,06546883 0,1259016 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,06546883 0,12579642 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,06546883 0,12569141 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,06546883 0,12558658 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,06546883 0,12548193 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,06546883 0,12537745 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,06546883 0,12527314 ! GTP metabolic process GO:0046039 9 9 0,000 0,06546883 0,125169 ! elastic fiber assembly GO:0048251 13 9 0,000 0,06546883 0,12506504 ! social behavior GO:0035176 14 9 0,000 0,06546883 0,12496125 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,06546883 0,12485764 ! artery development GO:0060840 19 9 0,000 0,06546883 0,12475419 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,06546883 0,12465092 ! response to pain GO:0048265 16 9 0,000 0,06546883 0,12454782 ! protein complex disassembly GO:0043241 17 9 0,000 0,06546883 0,12444489 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,06546883 0,12434212 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,06546883 0,12423953 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,06546883 0,12413711 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,06546883 0,12403485 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,06546883 0,12393277 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,06546883 0,12383085 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,06546883 0,1237291 ! ventral spinal cord development GO:0021517 11 9 0,000 0,06546883 0,12362751 ! protein targeting to ER GO:0045047 19 9 0,000 0,06546883 0,1235261 ! endoderm development GO:0007492 12 9 0,000 0,06546883 0,12342485 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,06546883 0,12332376 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,06546883 0,12322284 ! arginine catabolic process GO:0006527 10 9 0,000 0,06546883 0,12312209 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,06546883 0,1230215 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,06546883 0,12292107 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,06546883 0,12282081 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,06546883 0,12272071 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,06546883 0,12262078 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,06546883 0,122521 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,06546883 0,12242139 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,06546883 0,12232194 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06546883 0,12222266 ! mannose metabolic process GO:0006013 9 9 0,000 0,06546883 0,12212353 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,06546883 0,12202456 ! receptor clustering GO:0043113 15 9 0,000 0,06546883 0,12192576 ! epithelial cell development GO:0002064 10 9 0,000 0,06546883 0,12182711 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,06546883 0,12172863 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,06546883 0,1216303 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,06546883 0,12153213 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,06546883 0,12143412 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,06546883 0,12133627 ! motor axon guidance GO:0008045 14 9 0,000 0,06546883 0,12123858 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,06546883 0,12114104 ! blastoderm segmentation GO:0007350 11 9 0,000 0,06546883 0,12104366 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,06546883 0,12094644 ! DNA ligation GO:0006266 14 9 0,000 0,06546883 0,12084937 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,06546883 0,12075246 ! response to amine stimulus GO:0014075 13 9 0,000 0,06546883 0,1206557 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,06546883 0,1205591 ! erythrocyte development GO:0048821 11 9 0,000 0,06546883 0,12046265 ! renal water homeostasis GO:0003091 14 9 0,000 0,06546883 0,12036636 ! postreplication repair GO:0006301 11 9 0,000 0,06546883 0,12027022 ! mRNA cleavage GO:0006379 13 9 0,000 0,06546883 0,12017423 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,06546883 0,1200784 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,06546883 0,11998272 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,06546883 0,11988719 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,06546883 0,11979182 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,06546883 0,11969659 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,06546883 0,11960152 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,06546883 0,1195066 ! acid secretion GO:0046717 14 9 0,000 0,06546883 0,11941183 ! musculoskeletal movement GO:0050881 11 9 0,000 0,06546883 0,1193172 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,06546883 0,11922273 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,06546883 0,11912841 ! purine base metabolic process GO:0006144 18 9 0,000 0,06546883 0,11903424 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,06546883 0,11894021 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,06546883 0,11884634 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,06546883 0,11875261 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,06546883 0,11865903 ! detection of calcium ion GO:0005513 13 9 0,000 0,06546883 0,1185656 ! blastocyst formation GO:0001825 12 9 0,000 0,06546883 0,11847231 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,06546883 0,11837918 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,06546883 0,11828618 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,06546883 0,11819334 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,06546883 0,11810064 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06546883 0,11800808 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,06546883 0,11791567 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,06546883 0,11782341 ! prepulse inhibition GO:0060134 14 9 0,000 0,06546883 0,11773128 ! embryonic placenta development GO:0001892 12 9 0,000 0,06546883 0,11763931 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,06546883 0,11754747 ! insulin secretion GO:0030073 17 9 0,000 0,06546883 0,11745578 ! establishment of cell polarity GO:0030010 12 9 0,000 0,06546883 0,11736423 ! regulation of synapse organization GO:0050807 12 9 0,000 0,06546883 0,11727283 ! localization within membrane GO:0051668 15 9 0,000 0,06546883 0,11718157 ! camera-type eye development GO:0043010 88 57 1,000 0,06810151 0,12179896 ! secondary metabolic process GO:0019748 84 57 1,000 0,06810151 0,12170432 ! carbohydrate transport GO:0008643 74 57 1,000 0,06810151 0,12160983 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,06810151 0,12151549 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 1,000 0,06810151 0,12142129 ! viral reproductive process GO:0022415 87 58 1,000 0,07019803 0,12506233 ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,07019803 0,12496553 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 1,000 0,07231554 0,12863553 ! activation of MAPK activity GO:0000187 84 59 1,000 0,07231554 0,12853612 ! actin filament organization GO:0007015 95 59 1,000 0,07231554 0,12843686 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,07247527 0,12862124 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,07247527 0,12852208 ! neuron fate specification GO:0048665 11 10 0,000 0,07247527 0,12842306 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,07247527 0,1283242 ! thyroid gland development GO:0030878 19 10 0,000 0,07247527 0,12822549 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,07247527 0,12812693 ! synapsis GO:0007129 13 10 0,000 0,07247527 0,12802852 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,07247527 0,12793026 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,07247527 0,12783216 GO:0007520|myoblast fusion, ! sulfate transport GO:0008272 12 10 0,000 0,07247527 0,1277342 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,07247527 0,12763639 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,07247527 0,12753874 ! phospholipid efflux GO:0033700 16 10 0,000 0,07247527 0,12744123 ! hippocampus development GO:0021766 19 10 0,000 0,07247527 0,12734387 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,07247527 0,12724667 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,07247527 0,1271496 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,07247527 0,12705269 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,07247527 0,12695593 ! pathogenesis GO:0009405 13 10 0,000 0,07247527 0,12685931 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,07247527 0,12676284 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,07247527 0,12666651 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,07247527 0,12657034 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,07247527 0,1264743 ! melanocyte differentiation GO:0030318 15 10 0,000 0,07247527 0,12637842 GO:0050931|pigment cell differentiation, ! polyamine metabolic process GO:0006595 14 10 0,000 0,07247527 0,12628268 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07247527 0,12618708 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,07247527 0,12609163 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,07247527 0,12599632 ! forebrain cell migration GO:0021885 17 10 0,000 0,07247527 0,12590116 ! lipid digestion GO:0044241 15 10 0,000 0,07247527 0,12580614 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,07247527 0,12571126 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,07247527 0,12561653 ! UV protection GO:0009650 14 10 0,000 0,07247527 0,12552194 ! entry into host cell GO:0030260 20 10 0,000 0,07247527 0,12542749 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,07247527 0,12533318 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,07247527 0,12523902 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,07247527 0,12514499 ! regulation of organ growth GO:0046620 11 10 0,000 0,07247527 0,12505111 ! response to dsRNA GO:0043331 18 10 0,000 0,07247527 0,12495737 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,07247527 0,12486377 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07247527 0,12477031 ! embryonic axis specification GO:0000578 12 10 0,000 0,07247527 0,12467699 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,07247527 0,12458381 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,07247527 0,12449076 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,07247527 0,12439786 ! cranial nerve development GO:0021545 12 10 0,000 0,07247527 0,12430509 ! fucose catabolic process GO:0019317 16 10 0,000 0,07247527 0,12421247 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,07247527 0,12411998 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,07247527 0,12402763 ! protein sumoylation GO:0016925 12 10 0,000 0,07247527 0,12393541 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,07247527 0,12384334 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07247527 0,1237514 ! zymogen activation GO:0031638 14 10 0,000 0,07247527 0,12365959 ! salivary gland development GO:0007431 22 10 0,000 0,07247527 0,12356793 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07247527 0,12347639 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,07247527 0,123385 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,07247527 0,12329374 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,07247527 0,12320261 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07247527 0,12311162 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,07247527 0,12302076 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,07247527 0,12293004 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,07247527 0,12283945 ! detection of bacterium GO:0016045 10 10 0,000 0,07247527 0,12274899 ! embryonic gut development GO:0048566 11 10 0,000 0,07247527 0,12265867 ! activation of innate immune response GO:0002218 10 10 0,000 0,07247527 0,12256848 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,07247527 0,12247842 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,07247527 0,1223885 ! developmental induction GO:0031128 13 10 0,000 0,07247527 0,1222987 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,07247527 0,12220904 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,07247527 0,12211951 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,07247527 0,12203011 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,07445361 0,12526942 ! meiosis GO:0007126 96 61 1,000 0,07661182 0,12880642 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 97 62 1,000 0,07878975 0,13237138 ! rRNA transcription GO:0009303 17 11 0,000 0,07942959 0,13334894 ! respiratory burst GO:0045730 14 11 0,000 0,07942959 0,13325168 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,07942959 0,13315455 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,07942959 0,13305757 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,07942959 0,13296073 GO:0000725|recombinational repair, ! Golgi vesicle budding GO:0048194 17 11 0,000 0,07942959 0,13286404 ! RNA polyadenylation GO:0043631 19 11 0,000 0,07942959 0,13276748 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,07942959 0,13267106 ! mating GO:0007618 14 11 0,000 0,07942959 0,13257478 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,07942959 0,13247864 ! T cell proliferation GO:0042098 20 11 0,000 0,07942959 0,13238264 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,07942959 0,13228678 ! bone resorption GO:0045453 16 11 0,000 0,07942959 0,13219106 ! regulated secretory pathway GO:0045055 14 11 0,000 0,07942959 0,13209548 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,07942959 0,13200004 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,07942959 0,13190473 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,07942959 0,13180956 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,07942959 0,13171453 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,07942959 0,13161963 ! syncytium formation GO:0006949 15 11 0,000 0,07942959 0,13152487 ! plasma membrane organization GO:0007009 18 11 0,000 0,07942959 0,13143025 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,07942959 0,13133576 ! mitotic spindle organization GO:0007052 15 11 0,000 0,07942959 0,13124141 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,07942959 0,1311472 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,07942959 0,13105312 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,07942959 0,13095917 ! adult heart development GO:0007512 11 11 0,000 0,07942959 0,13086536 ! temperature homeostasis GO:0001659 16 11 0,000 0,07942959 0,13077169 ! L-glutamate transport GO:0015813 16 11 0,000 0,07942959 0,13067815 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,07942959 0,13058474 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,07942959 0,13049146 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,07942959 0,13039832 ! stem cell development GO:0048864 29 11 0,000 0,07942959 0,13030531 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,07942959 0,13021244 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,07942959 0,13011969 ! vasoconstriction GO:0042310 15 11 0,000 0,07942959 0,13002708 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,07942959 0,1299346 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,07942959 0,12984225 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,07942959 0,12975003 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,07942959 0,12965795 ! ribosome assembly GO:0042255 13 11 0,000 0,07942959 0,12956599 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,07942959 0,12947417 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,07942959 0,12938247 ! chromatin silencing GO:0006342 19 11 0,000 0,07942959 0,12929091 ! nucleosome positioning GO:0016584 13 11 0,000 0,07942959 0,12919947 ! regulation of isotype switching GO:0045191 19 11 0,000 0,07942959 0,12910816 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,07942959 0,12901698 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,07942959 0,12892593 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,07942959 0,12883501 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,07942959 0,12874422 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,07942959 0,12865356 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,07942959 0,12856302 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,07942959 0,12847261 ! male genitalia development GO:0030539 13 11 0,000 0,07942959 0,12838233 ! cholesterol efflux GO:0033344 19 11 0,000 0,07942959 0,12829217 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,07942959 0,12820214 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,07942959 0,12811224 ! germ cell migration GO:0008354 18 11 0,000 0,07942959 0,12802246 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,07942959 0,12793281 ! defense response to fungus GO:0050832 12 11 0,000 0,07942959 0,12784328 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,07942959 0,12775388 ! lysogeny GO:0030069 18 11 0,000 0,07942959 0,1276646 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,07942959 0,12757545 ! acrosome reaction GO:0007340 13 11 0,000 0,07942959 0,12748643 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,07942959 0,12739752 ! viral reproduction GO:0016032 92 63 1,000 0,08098699 0,12980494 ! adaptive immune response GO:0002250 94 64 1,000 0,08320314 0,13326408 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! lactation GO:0007595 20 12 0,000 0,08633215 0,13817951 ! reproductive cellular process GO:0048610 14 12 0,000 0,08633215 0,13808341 ! tRNA modification GO:0006400 14 12 0,000 0,08633215 0,13798746 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,08633215 0,13789163 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,08633215 0,13779594 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,08633215 0,13770038 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,08633215 0,13760496 ! non-recombinational repair GO:0000726 19 12 0,000 0,08633215 0,13750966 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,08633215 0,1374145 ! peroxisomal transport GO:0043574 21 12 0,000 0,08633215 0,13731947 ! cartilage condensation GO:0001502 18 12 0,000 0,08633215 0,13722457 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,08633215 0,1371298 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,08633215 0,13703516 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,08633215 0,13694066 ! heart looping GO:0001947 15 12 0,000 0,08633215 0,13684628 ! palate development GO:0060021 15 12 0,000 0,08633215 0,13675203 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,08633215 0,13665791 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,08633215 0,13656393 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,08633215 0,13647007 ! arginine metabolic process GO:0006525 13 12 0,000 0,08633215 0,13637634 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,08633215 0,13628274 ! methionine metabolic process GO:0006555 13 12 0,000 0,08633215 0,13618927 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,08633215 0,13609592 ! Golgi organization GO:0007030 18 12 0,000 0,08633215 0,13600271 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,08633215 0,13590962 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,08633215 0,13581666 ! monoamine transport GO:0015844 13 12 0,000 0,08633215 0,13572382 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08633215 0,13563111 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,08633215 0,13553853 ! L-amino acid transport GO:0015807 20 12 0,000 0,08633215 0,13544608 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,08633215 0,13535375 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,08633215 0,13526155 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,08633215 0,13516947 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08633215 0,13507752 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,08633215 0,13498569 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,08633215 0,13489399 ! cerebellum development GO:0021549 13 12 0,000 0,08633215 0,13480241 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,08633215 0,13471096 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,08633215 0,13461963 ! histone methylation GO:0016571 15 12 0,000 0,08633215 0,13452842 ! autonomic nervous system development GO:0048483 23 12 0,000 0,08633215 0,13443734 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,08633215 0,13434638 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,08633215 0,13425554 ! regulation of epidermis development GO:0045682 17 12 0,000 0,08633215 0,13416483 ! intestinal absorption GO:0050892 19 12 0,000 0,08633215 0,13407424 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,08633215 0,13398377 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,08633215 0,13389343 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,08633215 0,1338032 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,08633215 0,1337131 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,08633215 0,13362312 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,08633215 0,13353325 ! response to cold GO:0009409 14 12 0,000 0,08633215 0,13344351 ! antigen processing and presentation GO:0019882 96 66 1,000 0,08769055 0,13545216 ! regulation of immune effector process GO:0002697 101 66 1,000 0,08769055 0,13536125 ! rhythmic process GO:0048511 105 68 1,000 0,09224882 0,14230201 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,09318335 0,14364726 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,09318335 0,14355105 ! cGMP metabolic process GO:0046068 16 13 0,000 0,09318335 0,14345496 GO:0006182|cGMP biosynthetic process, ! water transport GO:0006833 17 13 0,000 0,09318335 0,14335901 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,09318335 0,14326318 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,09318335 0,14316748 ! lipid localization GO:0010876 24 13 0,000 0,09318335 0,1430719 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,09318335 0,14297646 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,09318335 0,14288114 ! organelle fusion GO:0048284 28 13 0,000 0,09318335 0,14278595 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,09318335 0,14269089 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,09318335 0,14259595 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,09318335 0,14250114 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,09318335 0,14240645 ! response to hexose stimulus GO:0009746 19 13 0,000 0,09318335 0,14231189 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,09318335 0,14221746 ! glutamate metabolic process GO:0006536 18 13 0,000 0,09318335 0,14212315 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,09318335 0,14202897 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,09318335 0,14193491 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,09318335 0,14184098 ! NAD metabolic process GO:0019674 21 13 0,000 0,09318335 0,14174716 ! exocrine system development GO:0035272 27 13 0,000 0,09318335 0,14165348 ! bone mineralization GO:0030282 15 13 0,000 0,09318335 0,14155992 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,09318335 0,14146648 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,09318335 0,14137316 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,09318335 0,14127997 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,09318335 0,1411869 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,09318335 0,14109395 ! genitalia development GO:0048806 15 13 0,000 0,09318335 0,14100113 ! tissue regeneration GO:0042246 21 13 0,000 0,09318335 0,14090842 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,09318335 0,14081584 ! cofactor transport GO:0051181 19 13 0,000 0,09318335 0,14072338 ! NADP metabolic process GO:0006739 18 13 0,000 0,09318335 0,14063105 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,09318335 0,14053883 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,09318335 0,14044673 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,09318335 0,14035476 ! gas transport GO:0015669 18 13 0,000 0,09318335 0,1402629 ! heme biosynthetic process GO:0006783 20 13 0,000 0,09318335 0,14017117 ! regulation of axon extension GO:0030516 23 13 0,000 0,09318335 0,14007955 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,09318335 0,13998806 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,09318335 0,13989668 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,09318335 0,13980542 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,09318335 0,13971429 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,09318335 0,13962327 ! humoral immune response GO:0006959 86 70 1,000 0,09687489 0,14506005 ! eye development GO:0001654 111 70 1,000 0,09687489 0,14496567 ! muscle cell differentiation GO:0042692 104 71 1,000 0,0992124 0,14836704 ! superoxide anion generation GO:0042554 18 14 0,000 0,09998357 0,14942314 ! neuron maturation GO:0042551 21 14 0,000 0,09998357 0,14932611 ! regulation of S phase GO:0033261 18 14 0,000 0,09998357 0,14922921 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,09998357 0,14913243 ! myotube differentiation GO:0014902 21 14 0,000 0,09998357 0,14903578 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,09998357 0,14893926 ! inositol metabolic process GO:0006020 20 14 0,000 0,09998357 0,14884286 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,09998357 0,14874658 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,09998357 0,14865043 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,09998357 0,1485544 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,09998357 0,1484585 ! gene silencing by RNA GO:0031047 20 14 0,000 0,09998357 0,14836272 ! response to cAMP GO:0051591 19 14 0,000 0,09998357 0,14826706 ! limbic system development GO:0021761 25 14 0,000 0,09998357 0,14817153 ! startle response GO:0001964 21 14 0,000 0,09998357 0,14807612 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,09998357 0,14798083 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,09998357 0,14788567 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,09998357 0,14779062 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,09998357 0,1476957 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,09998357 0,14760091 ! glycine metabolic process GO:0006544 22 14 0,000 0,09998357 0,14750623 ! pituitary gland development GO:0021983 23 14 0,000 0,09998357 0,14741167 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,09998357 0,14731724 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,09998357 0,14722293 ! regulation of heart rate GO:0002027 23 14 0,000 0,09998357 0,14712873 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,09998357 0,14703466 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,09998357 0,14694071 ! embryo implantation GO:0007566 27 14 0,000 0,09998357 0,14684688 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,09998357 0,14675317 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,09998357 0,14665957 ! axon cargo transport GO:0008088 27 14 0,000 0,09998357 0,1465661 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,09998357 0,14647275 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,09998357 0,14637951 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,09998357 0,14628639 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09998357 0,1461934 ! mRNA splice site selection GO:0006376 26 14 0,000 0,09998357 0,14610052 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,09998357 0,14600775 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,09998357 0,14591511 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,09998357 0,14582258 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,09998357 0,14573017 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,09998357 0,14563788 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,09998357 0,1455457 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,09998357 0,14545364 ! muscle maintenance GO:0046716 19 14 0,000 0,09998357 0,1453617 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,09998357 0,14526987 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,09998357 0,14517816 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,09998357 0,14508657 ! cell killing GO:0001906 20 14 0,000 0,09998357 0,14499509 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,09998357 0,14490372 ! cilium assembly GO:0042384 20 14 0,000 0,09998357 0,14481248 ! peptide hormone secretion GO:0030072 23 14 0,000 0,09998357 0,14472134 ! regulation of synaptic transmission GO:0050804 109 72 1,000 0,10156573 0,14691898 ! regulation of blood pressure GO:0008217 107 73 1,000 0,10393453 0,15025105 ! tube morphogenesis GO:0035239 118 73 1,000 0,10393453 0,15015667 ! cellular lipid catabolic process GO:0044242 105 73 1,000 0,10393453 0,15006241 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,10631843 0,15340803 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,10673318 0,15390991 ! positive regulation of cell size GO:0045793 20 15 0,000 0,10673318 0,15381348 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,10673318 0,15371716 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,10673318 0,15362097 ! skin development GO:0043588 25 15 0,000 0,10673318 0,1535249 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,10673318 0,15342894 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,10673318 0,15333311 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,10673318 0,1532374 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,10673318 0,1531418 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,10673318 0,15304633 ! bile acid metabolic process GO:0008206 22 15 0,000 0,10673318 0,15295097 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,10673318 0,15285573 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,10673318 0,15276062 ! adult walking behavior GO:0007628 25 15 0,000 0,10673318 0,15266562 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,10673318 0,15257073 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,10673318 0,15247597 ! myoblast differentiation GO:0045445 27 15 0,000 0,10673318 0,15238132 ! centrosome cycle GO:0007098 16 15 0,000 0,10673318 0,15228679 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,10673318 0,15219238 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,10673318 0,15209809 ! cerebral cortex development GO:0021987 29 15 0,000 0,10673318 0,15200391 ! response to osmotic stress GO:0006970 22 15 0,000 0,10673318 0,15190984 ! vesicle coating GO:0006901 25 15 0,000 0,10673318 0,1518159 ! DNA integration GO:0015074 22 15 0,000 0,10673318 0,15172207 ! peptide secretion GO:0002790 27 15 0,000 0,10673318 0,15162836 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,10673318 0,15153476 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,10673318 0,15144128 ! neuron recognition GO:0008038 22 15 0,000 0,10673318 0,15134791 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,10673318 0,15125466 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,10673318 0,15116152 ! biomineral formation GO:0031214 18 15 0,000 0,10673318 0,1510685 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,10673318 0,15097559 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,10673318 0,1508828 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,10673318 0,15079012 ! dopamine metabolic process GO:0042417 30 15 0,000 0,10673318 0,15069755 ! organic cation transport GO:0015695 19 15 0,000 0,10673318 0,1506051 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,10673318 0,15051276 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,10673318 0,15042053 ! peptide hormone processing GO:0016486 19 15 0,000 0,10673318 0,15032842 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,10673318 0,15023642 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,11113013 0,15632985 ! protein secretion GO:0009306 27 16 0,000 0,11343255 0,15947119 ! hormone secretion GO:0046879 25 16 0,000 0,11343255 0,15937377 ! bone remodeling GO:0046849 24 16 0,000 0,11343255 0,15927648 ! endothelial cell migration GO:0043542 22 16 0,000 0,11343255 0,1591793 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,11343255 0,15908224 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,11343255 0,15898529 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,11343255 0,15888847 ! glial cell development GO:0021782 24 16 0,000 0,11343255 0,15879176 ! patterning of blood vessels GO:0001569 24 16 0,000 0,11343255 0,15869518 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,11343255 0,1585987 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,11343255 0,15850235 ! protein polyubiquitination GO:0000209 26 16 0,000 0,11343255 0,15840611 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,11343255 0,15830999 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,11343255 0,15821399 ! fructose metabolic process GO:0006000 20 16 0,000 0,11343255 0,1581181 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,11343255 0,15802233 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,11343255 0,15792668 ! negative regulation of immune response GO:0050777 28 16 0,000 0,11343255 0,15783114 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,11343255 0,15773571 ! DNA replication initiation GO:0006270 25 16 0,000 0,11343255 0,1576404 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,11343255 0,15754521 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,11343255 0,15745013 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,11343255 0,15735517 ! diencephalon development GO:0021536 25 16 0,000 0,11343255 0,15726032 ! neural crest cell migration GO:0001755 24 16 0,000 0,11343255 0,15716558 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,11343255 0,15707096 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,11343255 0,15697645 ! steroid catabolic process GO:0006706 22 16 0,000 0,11343255 0,15688206 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,11343255 0,15678778 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,11343255 0,15669361 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,11343255 0,15659956 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,11343255 0,15650562 ! sperm-egg recognition GO:0035036 16 16 0,000 0,11343255 0,15641179 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,11343255 0,15631808 ! nerve development GO:0021675 18 16 0,000 0,11343255 0,15622447 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,11343255 0,15613098 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,11343255 0,1560376 ! protein ubiquitination GO:0016567 125 77 1,000 0,11355724 0,15611575 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 0,11355724 0,15602249 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,11355724 0,15592934 ! nitrogen compound catabolic process GO:0044270 114 78 1,000 0,11599805 0,15918586 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,12008206 0,16469215 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,12008206 0,164594 ! negative regulation of defense response GO:0031348 19 17 0,000 0,12008206 0,16449597 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,12008206 0,16439806 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,12008206 0,16430026 ! glycerol metabolic process GO:0006071 20 17 0,000 0,12008206 0,16420258 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,12008206 0,16410501 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,12008206 0,16400757 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,12008206 0,16391023 ! signal complex assembly GO:0007172 29 17 0,000 0,12008206 0,16381301 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,12008206 0,16371591 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,12008206 0,16361892 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,12008206 0,16352205 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,12008206 0,16342529 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,12008206 0,16332865 ! memory GO:0007613 25 17 0,000 0,12008206 0,16323212 ! keratinization GO:0031424 17 17 0,000 0,12008206 0,1631357 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,12008206 0,1630394 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,12008206 0,16294321 ! retinoid metabolic process GO:0001523 22 17 0,000 0,12008206 0,16284713 GO:0016101|diterpenoid metabolic process, ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,12008206 0,16275117 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,12008206 0,16265532 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,12008206 0,16255959 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,12008206 0,16246396 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,12008206 0,16236845 ! membrane budding GO:0006900 29 17 0,000 0,12008206 0,16227306 ! actin filament bundle formation GO:0051017 26 17 0,000 0,12008206 0,16217777 ! neuromuscular junction development GO:0007528 23 17 0,000 0,12008206 0,16208259 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,12008206 0,16198753 ! body fluid secretion GO:0007589 27 17 0,000 0,12008206 0,16189258 ! stem cell differentiation GO:0048863 36 17 0,000 0,12008206 0,16179774 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,12008206 0,16170301 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,12008206 0,16160839 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,12008206 0,16151388 ! sensory perception of pain GO:0019233 23 17 0,000 0,12008206 0,16141949 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,12008206 0,1613252 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,12008206 0,16123102 ! synaptogenesis GO:0007416 24 17 0,000 0,12008206 0,16113695 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,12008206 0,161043 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,12008206 0,16094915 ! cell-cell junction organization GO:0045216 25 17 0,000 0,12008206 0,16085541 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,12008206 0,16076178 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,12008206 0,16066826 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,12008206 0,16057485 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,12008206 0,16048155 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,12008206 0,16038835 ! regulation of neurological system process GO:0031644 122 81 1,000 0,12339939 0,1647235 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,12339939 0,16462795 GO:0002696|positive regulation of leukocyte activation, ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,12668208 0,16890943 ! positive regulation of translation GO:0045727 28 18 0,000 0,12668208 0,16881157 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,12668208 0,16871382 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,12668208 0,16861619 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,12668208 0,16851867 ! cAMP metabolic process GO:0046058 33 18 0,000 0,12668208 0,16842126 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,12668208 0,16832396 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,12668208 0,16822677 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,12668208 0,1681297 ! axis specification GO:0009798 26 18 0,000 0,12668208 0,16803274 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,12668208 0,16793589 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,12668208 0,16783916 ! pancreas development GO:0031016 26 18 0,000 0,12668208 0,16774253 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,12668208 0,16764601 ! glutamine metabolic process GO:0006541 23 18 0,000 0,12668208 0,16754961 ! central nervous system neuron development GO:0021954 30 18 0,000 0,12668208 0,16745332 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,12668208 0,16735714 ! fucose metabolic process GO:0006004 26 18 0,000 0,12668208 0,16726106 ! response to fungus GO:0009620 19 18 0,000 0,12668208 0,1671651 ! peptide cross-linking GO:0018149 31 18 0,000 0,12668208 0,16706925 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,12668208 0,16697351 ! heart process GO:0003015 27 18 0,000 0,12668208 0,16687788 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,12668208 0,16678235 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,12668208 0,16668694 ! visual learning GO:0008542 35 18 0,000 0,12668208 0,16659164 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,12668208 0,16649644 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,12668208 0,16640136 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,12668208 0,16630638 ! vitamin transport GO:0051180 24 18 0,000 0,12668208 0,16621151 ! hormone transport GO:0009914 27 18 0,000 0,12668208 0,16611675 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,12668208 0,16602209 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,12668208 0,16592755 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,12668208 0,16583311 ! cell-cell recognition GO:0009988 20 18 0,000 0,12668208 0,16573878 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,12668208 0,16564456 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,12668208 0,16555044 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,13323296 0,17401238 ! positive regulation of ossification GO:0045778 30 19 0,000 0,13323296 0,17391363 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,13323296 0,17381498 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,13323296 0,17371644 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,13323296 0,17361802 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,13323296 0,17351971 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,13323296 0,17342151 ! sensory perception of taste GO:0050909 23 19 0,000 0,13323296 0,17332342 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,13323296 0,17322544 ! smooth muscle contraction GO:0006939 36 19 0,000 0,13323296 0,17312757 ! peroxisome organization GO:0007031 29 19 0,000 0,13323296 0,17302982 ! digestive system process GO:0022600 30 19 0,000 0,13323296 0,17293217 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,13323296 0,17283463 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,13323296 0,17273721 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,13323296 0,17263989 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,13323296 0,17254268 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,13323296 0,17244559 ! plasma membrane fusion GO:0045026 23 19 0,000 0,13323296 0,1723486 ! cytolysis GO:0019835 20 19 0,000 0,13323296 0,17225172 ! vasodilation GO:0042311 33 19 0,000 0,13323296 0,17215495 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,13323296 0,17205829 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,13323296 0,17196173 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,13323296 0,17186529 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,13323296 0,17176895 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,13323296 0,17167272 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,13323296 0,1715766 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,13323296 0,17148059 ! sarcomere organization GO:0045214 23 19 0,000 0,13323296 0,17138468 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,13323296 0,17128888 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,13323296 0,17119319 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,13323296 0,1710976 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,13323296 0,17100212 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,13323296 0,17090675 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,13323296 0,17081149 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,13323296 0,17071633 ! rRNA metabolic process GO:0016072 107 85 1,000 0,13343977 0,17088612 GO:0006364|rRNA processing, ! regulation of protein localization GO:0032880 132 85 1,000 0,13343977 0,17079103 ! regulation of membrane potential GO:0042391 128 85 1,000 0,13343977 0,17069604 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,13852797 0,17710635 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 1,000 0,13852797 0,17700796 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,13852797 0,17690967 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,13973508 0,17835221 ! iron ion transport GO:0006826 37 20 0,000 0,13973508 0,17825329 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,13973508 0,17815448 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,13973508 0,17805578 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,13973508 0,17795719 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,13973508 0,1778587 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,13973508 0,17776033 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,13973508 0,17766207 ! spinal cord development GO:0021510 31 20 0,000 0,13973508 0,17756391 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,13973508 0,17746586 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,13973508 0,17736792 ! chromosome condensation GO:0030261 31 20 0,000 0,13973508 0,17727009 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,13973508 0,17717237 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,13973508 0,17707475 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,13973508 0,17697725 ! pallium development GO:0021543 38 20 0,000 0,13973508 0,17687985 ! DNA modification GO:0006304 28 20 0,000 0,13973508 0,17678255 ! collagen fibril organization GO:0030199 45 20 0,000 0,13973508 0,17668536 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,13973508 0,17658828 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,13973508 0,17649131 ! collagen catabolic process GO:0030574 25 20 0,000 0,13973508 0,17639444 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,13973508 0,17629768 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,13973508 0,17620103 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,13973508 0,17610448 ! alditol metabolic process GO:0019400 24 20 0,000 0,13973508 0,17600804 ! actin filament-based movement GO:0030048 34 20 0,000 0,13973508 0,1759117 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,14108799 0,17751771 ! regulation of T cell activation GO:0050863 128 89 1,000 0,14365824 0,18065278 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,14618879 0,18373454 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,14618879 0,1836342 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,14618879 0,18353396 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,14618879 0,18343383 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,14618879 0,18333381 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,14618879 0,1832339 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,14618879 0,1831341 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,14618879 0,18303441 ! vesicle docking GO:0048278 27 21 0,000 0,14618879 0,18293483 ! phototransduction GO:0007602 25 21 0,000 0,14618879 0,18283535 ! dendrite development GO:0016358 35 21 0,000 0,14618879 0,18273599 ! visual behavior GO:0007632 39 21 0,000 0,14618879 0,18263673 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,14618879 0,18253758 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,14618879 0,18243853 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,14618879 0,1823396 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,14618879 0,18224077 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,14618879 0,18214204 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,14618879 0,18204343 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,14618879 0,18194492 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,14618879 0,18184652 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,14618879 0,18174822 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,14618879 0,18165003 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,14618879 0,18155195 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,14618879 0,18145397 ! immunoglobulin production GO:0002377 33 21 0,000 0,14618879 0,1813561 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,14618879 0,18125834 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,14618879 0,18116068 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,14618879 0,18106312 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,14618879 0,18096567 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,14618879 0,18086832 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,14618879 0,18077108 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,14618879 0,18067395 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,14618879 0,18057691 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,14618879 0,18047999 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,14623841 0,18044439 ! ATP metabolic process GO:0046034 137 91 1,000 0,14882822 0,18354151 ! response to virus GO:0009615 122 91 1,000 0,14882822 0,18344315 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,15142739 0,18654686 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,15259445 0,18788396 ! viral genome replication GO:0019079 29 22 0,000 0,15259445 0,18778343 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,15259445 0,18768301 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,15259445 0,1875827 ! leukocyte adhesion GO:0007159 38 22 0,000 0,15259445 0,1874825 ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,15259445 0,1873824 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,15259445 0,18728241 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,15259445 0,18718253 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,15259445 0,18708275 GO:0051297|centrosome organization, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,15259445 0,18698308 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,15259445 0,18688351 ! lysosome organization GO:0007040 37 22 0,000 0,15259445 0,18678405 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,15259445 0,1866847 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,15259445 0,18658545 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,15259445 0,18648631 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,15259445 0,18638727 ! membrane depolarization GO:0051899 35 22 0,000 0,15259445 0,18628834 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,15259445 0,18618952 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,15259445 0,18609079 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,15259445 0,18599218 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,15259445 0,18589366 ! blastocyst development GO:0001824 37 22 0,000 0,15259445 0,18579526 ! neural tube closure GO:0001843 33 22 0,000 0,15259445 0,18569695 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,15259445 0,18559875 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,15403562 0,1872526 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,15895242 0,19312761 ! neuron fate commitment GO:0048663 32 23 0,000 0,15895242 0,19302564 ! embryonic pattern specification GO:0009880 31 23 0,000 0,15895242 0,19292378 ! myelination GO:0042552 35 23 0,000 0,15895242 0,19282203 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,15895242 0,19272038 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,15895242 0,19261884 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,15895242 0,19251741 ! vesicle targeting GO:0006903 32 23 0,000 0,15895242 0,19241609 ! osteoblast differentiation GO:0001649 40 23 0,000 0,15895242 0,19231487 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,15895242 0,19221376 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,15895242 0,19211275 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,15895242 0,19201185 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,15895242 0,19191106 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,15895242 0,19181037 ! cell fate determination GO:0001709 45 23 0,000 0,15895242 0,19170979 ! pentose metabolic process GO:0019321 31 23 0,000 0,15895242 0,19160931 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,15895242 0,19150894 ! spermatid development GO:0007286 33 23 0,000 0,15895242 0,19140867 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,15895242 0,19130851 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,15895242 0,19120845 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,15895242 0,1911085 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,15895242 0,19100865 ! telomere organization GO:0032200 32 23 0,000 0,15895242 0,19090891 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,15895242 0,19080927 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,15895242 0,19070974 ! regulation of amine transport GO:0051952 38 23 0,000 0,15895242 0,1906103 ! carboxylic acid transport GO:0046942 147 95 1,000 0,15927818 0,19090142 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 1,000 0,16191197 0,19395705 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,16191197 0,19385608 ! protein maturation GO:0051604 129 96 1,000 0,16191197 0,19375522 ! initiation of viral infection GO:0019059 42 24 0,000 0,16526305 0,19766251 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,16526305 0,19755977 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,16526305 0,19745715 ! superoxide metabolic process GO:0006801 32 24 0,000 0,16526305 0,19735462 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,16526305 0,19725221 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,16526305 0,1971499 ! sperm motility GO:0030317 27 24 0,000 0,16526305 0,1970477 ! vacuole organization GO:0007033 39 24 0,000 0,16526305 0,1969456 ! receptor metabolic process GO:0043112 37 24 0,000 0,16526305 0,19684361 ! neural crest cell development GO:0014032 39 24 0,000 0,16526305 0,19674172 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,16526305 0,19663994 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,16526305 0,19653827 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,16526305 0,1964367 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,16526305 0,19633523 ! glutathione metabolic process GO:0006749 29 24 0,000 0,16526305 0,19623387 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,16526305 0,19613261 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,16526305 0,19603146 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,16526305 0,19593042 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,17152668 0,20325161 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,17152668 0,20314694 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,17152668 0,20304239 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,17152668 0,20293795 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,17152668 0,20283361 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,17152668 0,20272938 ! peptide transport GO:0015833 43 25 0,000 0,17152668 0,20262525 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,17152668 0,20252124 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,17152668 0,20241733 ! phospholipid transport GO:0015914 35 25 0,000 0,17152668 0,20231352 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,17152668 0,20220982 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,17152668 0,20210623 ! detection of light stimulus GO:0009583 30 25 0,000 0,17152668 0,20200275 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 1,000 0,17252424 0,20307357 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,17252424 0,20296969 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,17252424 0,20286593 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,17774367 0,2088965 ! translational initiation GO:0006413 43 26 0,000 0,17774367 0,20878981 ! circadian rhythm GO:0007623 42 26 0,000 0,17774367 0,20868323 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,17774367 0,20857676 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,17774367 0,2084704 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,17774367 0,20836414 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,17774367 0,208258 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,17774367 0,20815196 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,17774367 0,20804603 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,17774367 0,20794021 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,17774367 0,20783449 ! regulation of coagulation GO:0050818 39 26 0,000 0,17774367 0,20772888 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,18391436 0,2148314 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,18391436 0,21472235 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,18391436 0,21461341 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,18391436 0,21450458 ! membrane docking GO:0022406 39 27 0,000 0,18391436 0,21439586 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,18391436 0,21428725 ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,18391436 0,21417875 ! acute-phase response GO:0006953 42 27 0,000 0,18391436 0,21407036 ! myofibril assembly GO:0030239 36 27 0,000 0,18391436 0,21396208 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,18391436 0,21385391 ! natural killer cell activation GO:0030101 35 27 0,000 0,18391436 0,21374585 ! lipid oxidation GO:0034440 38 27 0,000 0,18391436 0,2136379 GO:0019395|fatty acid oxidation, ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,18391436 0,21353005 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,18391436 0,21342232 ! gene silencing GO:0016458 41 27 0,000 0,18391436 0,21331469 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,1900391 0,22030742 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,1900391 0,22019643 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,1900391 0,22008556 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,1900391 0,2199748 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,1900391 0,21986415 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,1900391 0,21975361 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,1900391 0,21964318 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,1900391 0,21953286 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,1900391 0,21942265 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,1900391 0,21931255 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,1900391 0,21920257 ! mesoderm formation GO:0001707 46 28 0,000 0,1900391 0,21909269 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,1900391 0,21898293 ! ensheathment of neurons GO:0007272 43 28 0,000 0,1900391 0,21887327 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,1900391 0,21876372 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,1900391 0,21865429 ! neural tube formation GO:0001841 41 28 0,000 0,1900391 0,21854496 ! regulation of innate immune response GO:0045088 38 29 0,000 0,19611821 0,22542323 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,19611821 0,22531063 ! protein targeting to membrane GO:0006612 53 29 0,000 0,19611821 0,22519815 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,19611821 0,22508577 ! mismatch repair GO:0006298 34 29 0,000 0,19611821 0,22497351 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,19611821 0,22486136 ! muscle cell development GO:0055001 38 29 0,000 0,19611821 0,22474932 ! formation of primary germ layer GO:0001704 48 29 0,000 0,19611821 0,22463739 ! telencephalon development GO:0021537 52 29 0,000 0,19611821 0,22452558 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,19611821 0,22441387 ! eye morphogenesis GO:0048592 51 29 0,000 0,19611821 0,22430228 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,19611821 0,2241908 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,20215205 0,23097352 ! collagen metabolic process GO:0032963 40 30 0,000 0,20215205 0,23085884 ! organic anion transport GO:0015711 51 30 0,000 0,20215205 0,23074427 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,20215205 0,23062981 ! spliceosome assembly GO:0000245 49 30 0,000 0,20215205 0,23051547 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,20215205 0,23040124 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,20215205 0,23028712 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,20215205 0,23017312 ! ceramide metabolic process GO:0006672 43 30 0,000 0,20215205 0,23005923 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,20215205 0,22994545 ! adult locomotory behavior GO:0008344 47 30 0,000 0,20215205 0,22983179 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,20215205 0,22971823 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,20215205 0,22960479 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,20215205 0,22949146 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,20215205 0,22937825 ! mammary gland development GO:0030879 57 31 0,000 0,20814093 0,23605727 ! glial cell differentiation GO:0010001 55 31 0,000 0,20814093 0,23594093 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,20814093 0,2358247 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,20814093 0,23570859 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,20814093 0,23559259 ! odontogenesis GO:0042476 50 31 0,000 0,20814093 0,23547671 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,20814093 0,23536094 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,20814093 0,23524528 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,20814093 0,23512974 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,20814093 0,23501431 ! cell fate specification GO:0001708 37 31 0,000 0,20814093 0,23489899 ! RNA modification GO:0009451 40 31 0,000 0,20814093 0,23478379 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,21408521 0,24137058 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,21408521 0,24125232 ! peripheral nervous system development GO:0007422 53 32 0,000 0,21408521 0,24113417 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,21408521 0,24101614 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,21408521 0,24089823 ! cytokine production GO:0001816 44 32 0,000 0,21408521 0,24078043 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,21408521 0,24066275 ! vesicle localization GO:0051648 47 32 0,000 0,21408521 0,24054518 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,2199852 0,24705369 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,2199852 0,24693312 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,2199852 0,24681266 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,2199852 0,24669233 ! ear morphogenesis GO:0042471 42 33 0,000 0,2199852 0,2465721 ! actomyosin structure organization GO:0031032 43 33 0,000 0,2199852 0,246452 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,2199852 0,24633202 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,2199852 0,24621215 ! lipid homeostasis GO:0055088 55 33 0,000 0,2199852 0,24609239 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,2199852 0,24597276 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,2199852 0,24585324 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,2199852 0,24573383 ! mRNA catabolic process GO:0006402 48 34 0,000 0,22584123 0,25215283 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,22584123 0,25203049 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,22584123 0,25190826 ! feeding behavior GO:0007631 45 34 0,000 0,22584123 0,25178615 ! neuron migration GO:0001764 46 34 0,000 0,22584123 0,25166417 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,22584123 0,25154229 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,22584123 0,25142054 ! polyol metabolic process GO:0019751 44 34 0,000 0,22584123 0,25129891 ! aerobic respiration GO:0009060 47 34 0,000 0,22584123 0,25117739 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,22584123 0,25105599 ! embryonic organ development GO:0048568 45 34 0,000 0,22584123 0,2509347 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,22584123 0,25081354 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,23165364 0,25714448 ! Notch signaling pathway GO:0007219 56 35 0,000 0,23165364 0,25702044 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,23165364 0,25689651 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,23165364 0,25677271 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,23165364 0,25664902 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,23165364 0,25652545 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,23165364 0,256402 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,23165364 0,25627867 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,23165364 0,25615546 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,23165364 0,25603237 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,23742273 0,26228255 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,23742273 0,26215664 ! neural tube development GO:0021915 50 36 0,000 0,23742273 0,26203084 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,23742273 0,26190517 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,23742273 0,26177962 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,23742273 0,26165418 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,24314883 0,26783636 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,24314883 0,26770815 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,24314883 0,26758006 ! ion transmembrane transport GO:0034220 56 37 0,000 0,24314883 0,26745209 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,24314883 0,26732424 ! regulation of protein secretion GO:0050708 51 37 0,000 0,24314883 0,26719652 ! amino acid activation GO:0043038 52 37 0,000 0,24314883 0,26706892 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,24314883 0,26694144 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,24883227 0,27305068 ! gliogenesis GO:0042063 71 38 0,000 0,24883227 0,27292047 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,24883227 0,27279038 ! maintenance of location in cell GO:0051651 69 38 0,000 0,24883227 0,27266042 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,25447335 0,2787089 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,25447335 0,27857625 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,25447335 0,27844372 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,25447335 0,27831132 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,25447335 0,27817904 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,25447335 0,27804689 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,25447335 0,27791486 ! chromatin remodeling GO:0006338 68 39 0,000 0,25447335 0,27778296 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,25447335 0,27765118 ! synapse organization GO:0050808 55 39 0,000 0,25447335 0,27751953 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,26007238 0,28349122 ! regulation of tube size GO:0035150 60 40 0,000 0,26007238 0,28335693 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,26007238 0,28322277 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,26007238 0,28308873 ! peptide metabolic process GO:0006518 56 40 0,000 0,26007238 0,28295482 ! inner ear development GO:0048839 57 40 0,000 0,26007238 0,28282103 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,26007238 0,28268737 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,26007238 0,28255384 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,26007238 0,28242043 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,26007238 0,28228715 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,26562969 0,28818315 ! endosome transport GO:0016197 71 41 0,000 0,26562969 0,28804728 ! striated muscle contraction GO:0006941 62 41 0,000 0,26562969 0,28791154 ! biopolymer methylation GO:0043414 62 41 0,000 0,26562969 0,28777592 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,26562969 0,28764043 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,27114557 0,29347521 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,27114557 0,29333717 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,27114557 0,29319925 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,27114557 0,29306147 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,27114557 0,29292382 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,27114557 0,2927863 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,27114557 0,2926489 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,27114557 0,29251164 ! neuromuscular process GO:0050905 79 43 0,000 0,27662034 0,29827791 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,27662034 0,29813813 ! tRNA processing GO:0008033 49 43 0,000 0,27662034 0,29799849 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,27662034 0,29785898 ! methylation GO:0032259 64 43 0,000 0,27662034 0,2977196 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,28205429 0,30342604 ! glycolysis GO:0006096 53 44 0,000 0,28205429 0,30328419 ! regulation of action potential GO:0001508 71 44 0,000 0,28205429 0,30314246 ! regulation of ion transport GO:0043269 57 44 0,000 0,28205429 0,30300087 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,28205429 0,30285942 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,28205429 0,30271809 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,28205429 0,3025769 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,28205429 0,30243584 ! RNA catabolic process GO:0006401 64 45 0,000 0,28744774 0,30807539 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,28744774 0,3079319 ! cell recognition GO:0008037 58 45 0,000 0,28744774 0,30778855 ! cell maturation GO:0048469 60 45 0,000 0,28744774 0,30764532 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,29280097 0,31322895 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,29280097 0,31308333 ! cell redox homeostasis GO:0045454 63 46 0,000 0,29280097 0,31293784 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,29280097 0,31279249 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,29280097 0,31264728 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,29811429 0,31817303 ! viral infectious cycle GO:0019058 71 47 0,000 0,29811429 0,31802545 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,29811429 0,31787801 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,29811429 0,31773071 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,29811429 0,31758354 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,29811429 0,31743652 ! chloride transport GO:0006821 67 48 0,000 0,303388 0,32290254 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,303388 0,32275319 ! gastrulation GO:0007369 73 48 0,000 0,303388 0,32260397 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,303388 0,32245489 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,303388 0,32230595 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,303388 0,32215715 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,303388 0,32200849 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,30862238 0,32741304 ! sensory perception of smell GO:0007608 61 49 0,000 0,30862238 0,32726209 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,30862238 0,32711127 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,30862238 0,3269606 ! RNA elongation GO:0006354 62 49 0,000 0,30862238 0,32681007 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,30862238 0,32665967 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,30862238 0,32650941 ! regulation of actin filament length GO:0030832 72 50 0,000 0,31381772 0,33185322 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,31381772 0,33170072 ! membrane fusion GO:0006944 80 50 0,000 0,31381772 0,33154835 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,31381772 0,33139613 ! proton transport GO:0015992 75 50 0,000 0,31381772 0,33124404 ! positive regulation of secretion GO:0051047 71 51 0,000 0,31897432 0,33653254 ! hydrogen transport GO:0006818 77 51 0,000 0,31897432 0,33637824 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,31897432 0,33622408 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,31897432 0,33607006 ! adult behavior GO:0030534 80 51 0,000 0,31897432 0,33591618 ! transition metal ion transport GO:0000041 74 52 0,000 0,32409247 0,34114997 ! regulation of cellular component size GO:0032535 74 52 0,000 0,32409247 0,3409939 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,32409247 0,34083799 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,32409247 0,34068221 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,32917244 0,34586414 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,32917244 0,34570621 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,32917244 0,34554843 ! single fertilization GO:0007338 59 53 0,000 0,32917244 0,34539079 ! amino acid transport GO:0006865 84 54 0,000 0,33421452 0,35052138 ! glucose catabolic process GO:0006007 66 54 0,000 0,33421452 0,35036162 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,33421452 0,350202 ! detection of external stimulus GO:0009581 66 54 0,000 0,33421452 0,35004253 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,33421452 0,3498832 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,33421452 0,34972402 ! exocytosis GO:0006887 74 55 0,000 0,33921899 0,3547993 ! mesoderm development GO:0007498 76 55 0,000 0,33921899 0,35463803 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,33921899 0,35447691 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,33921899 0,35431593 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,34911621 0,3644881 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,34911621 0,36432272 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,35400951 0,36926162 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,3588663 0,37415798 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,36368686 0,37901213 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,36368686 0,37884048 GO:0035113|embryonic appendage morphogenesis, ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,36368686 0,37866898 ! fertilization GO:0009566 68 60 0,000 0,36368686 0,37849763 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,36847144 0,38330362 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,36847144 0,38313034 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,36847144 0,38295721 ! extracellular matrix organization GO:0030198 103 61 0,000 0,36847144 0,38278424 ! amine catabolic process GO:0009310 90 62 0,000 0,37322032 0,38754254 ! neurotransmitter transport GO:0006836 81 62 0,000 0,37322032 0,38736766 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,37322032 0,38719293 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,37322032 0,38701837 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,37793376 0,39172945 ! regulation of lipase activity GO:0060191 109 63 0,000 0,37793376 0,391553 ! appendage morphogenesis GO:0035107 93 64 0,000 0,38261202 0,39622137 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,38261202 0,39604305 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,38261202 0,39586489 ! hexose catabolic process GO:0019320 82 64 0,000 0,38261202 0,3956869 ! appendage development GO:0048736 94 65 0,000 0,38725537 0,40030892 GO:0060173|limb development, ! defense response to bacterium GO:0042742 73 65 0,000 0,38725537 0,40012909 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,38725537 0,39994942 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,38725537 0,39976991 ! activation of immune response GO:0002253 83 65 0,000 0,38725537 0,39959056 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,39186406 0,40416473 ! axon guidance GO:0007411 99 66 0,000 0,39186406 0,40398357 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,39186406 0,40380257 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,39643835 0,40833328 ! acute inflammatory response GO:0002526 92 68 0,000 0,40097849 0,41282477 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,40097849 0,41264006 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,40097849 0,41245552 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,40097849 0,41227114 ! inorganic anion transport GO:0015698 93 68 0,000 0,40097849 0,41208692 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,40548474 0,41653189 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,40548474 0,41634594 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,40995735 0,42075051 ! amine transport GO:0015837 101 70 0,000 0,40995735 0,42056285 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,40995735 0,42037535 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,41439656 0,42473801 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,41439656 0,42454882 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,41439656 0,42435979 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,41439656 0,42417094 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,42751631 0,43740548 ! digestion GO:0007586 97 74 0,000 0,42751631 0,43721099 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,43182441 0,44142051 ! tRNA metabolic process GO:0006399 95 76 0,000 0,43610033 0,44559341 ! regulation of protein transport GO:0051223 114 76 0,000 0,43610033 0,44539554 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,44034432 0,44953037 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,44034432 0,44933094 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,44034432 0,44913168 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,44455661 0,45322704 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,44873743 0,45728671 ! cellular respiration GO:0045333 107 79 0,000 0,44873743 0,45708419 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,44873743 0,45688185 ! regulation of lyase activity GO:0051339 133 79 0,000 0,44873743 0,45667969 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,44873743 0,45647771 ! chromatin assembly GO:0031497 102 80 0,000 0,45288703 0,46049521 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,45288703 0,46029172 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,45288703 0,46008841 ! forebrain development GO:0030900 131 80 0,000 0,45288703 0,45988528 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,45700562 0,46386272 ! mRNA transport GO:0051028 121 81 0,000 0,45700562 0,46365811 ! vitamin metabolic process GO:0006766 103 81 0,000 0,45700562 0,46345367 ! ossification GO:0001503 134 82 0,000 0,46109345 0,4673931 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,46109345 0,4671872 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,46515073 0,47109057 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,4691777 0,47495982 ! sterol metabolic process GO:0016125 120 84 0,000 0,4691777 0,47475087 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,47317459 0,47858467 ! transcription initiation GO:0006352 118 85 0,000 0,47317459 0,47837431 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,4771416 0,48217297 ! nucleosome organization GO:0034728 114 87 0,000 0,48107897 0,48593835 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,48107897 0,48572503 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,48107897 0,4855119 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,48498691 0,48924118 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,48498691 0,48902669 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,48498691 0,4888124 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,48498691 0,48859829 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,48886564 0,49229027 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,48886564 0,49207483 ! hormone metabolic process GO:0042445 121 90 0,000 0,49271539 0,49573289 ! RNA localization GO:0006403 135 91 0,000 0,49653636 0,49935882 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,50032876 0,50295286 ! positive regulation of immune response GO:0050778 121 92 0,000 0,50032876 0,50273314 ! DNA recombination GO:0006310 146 92 0,000 0,50032876 0,5025136 ! sulfur metabolic process GO:0006790 118 92 0,000 0,50032876 0,50229426 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,50409282 0,5058523 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,50409282 0,5056317 ! electron transport chain GO:0022900 123 94 0,000 0,50782873 0,50915697 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,51521698 0,51633946 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,51886972 0,51977368 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,52609347 0,52678057 ! extracellular structure organization GO:0043062 156 99 0,000 0,52609347 0,52655134 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,52966487 0,52989526 ! divalent metal ion transport GO:0070838 171 100 0,000 0,52966487 0,52966487