pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1137-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 115 46 6,000 4,916E-09 1,183E-05 ! nuclear migration GO:0007097 12 6 3,000 1,17E-08 1,408E-05 ! regulation of lipid kinase activity GO:0043550 13 7 3,000 2,719E-08 2,181E-05 ! interphase of mitotic cell cycle GO:0051329 209 95 7,000 4,589E-08 2,76E-05 ! establishment of nucleus localization GO:0040023 16 8 3,000 5,416E-08 2,606E-05 ! interphase GO:0051325 213 98 7,000 5,861E-08 2,35E-05 ! apoptotic mitochondrial changes GO:0008637 41 20 4,000 5,96E-08 2,049E-05 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 7,271E-08 2,187E-05 ! negative regulation of kinase activity GO:0033673 131 68 6,000 8,069E-08 2,157E-05 ! negative regulation of cell size GO:0045792 134 69 6,000 8,94E-08 2,151E-05 ! induction of positive chemotaxis GO:0050930 15 9 3,000 9,708E-08 2,123E-05 ! negative regulation of transferase activity GO:0051348 140 72 6,000 1,204E-07 2,415E-05 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 1,457E-07 2,697E-05 ! negative regulation of phosphorylation GO:0042326 47 24 4,000 1,606E-07 2,76E-05 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 2,464E-07 3,952E-05 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 4,000 2,464E-07 3,705E-05 GO:0045936|negative regulation of phosphate metabolic process, ! nucleus localization GO:0051647 19 11 3,000 2,521E-07 3,569E-05 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 3,766E-07 5,034E-05 GO:0050927|positive regulation of positive chemotaxis, ! response to UV GO:0009411 104 53 5,000 3,964E-07 5,02E-05 ! cellular response to extracellular stimulus GO:0031668 48 29 4,000 4,391E-07 5,283E-05 ! aging GO:0007568 103 55 5,000 4,962E-07 5,685E-05 ! regulation of cell cycle process GO:0010564 149 90 6,000 5,636E-07 6,164E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 6,157E-07 6,441E-05 ! response to peptide hormone stimulus GO:0043434 122 61 5,000 9,256E-07 9,279E-05 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 2,000 1,488E-06 1,432E-04 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 1,557E-06 1,441E-04 ! negative regulation of cell growth GO:0030308 132 67 5,000 1,62E-06 1,444E-04 ! microspike assembly GO:0030035 36 17 3,000 1,774E-06 1,524E-04 ! cell cycle checkpoint GO:0000075 137 69 5,000 1,929E-06 1,601E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 2,964E-06 2,377E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 5,000 4,281E-06 3,322E-04 ! cell aging GO:0007569 44 21 3,000 4,386E-06 3,298E-04 ! positive regulation of locomotion GO:0040017 39 21 3,000 4,386E-06 3,198E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! response to insulin stimulus GO:0032868 95 46 4,000 4,71E-06 3,333E-04 ! response to hypoxia GO:0001666 171 81 5,000 4,954E-06 3,406E-04 ! macrophage differentiation GO:0030225 11 7 2,000 5,166E-06 3,453E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 5,166E-06 3,359E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 5,166E-06 3,271E-04 ! T cell lineage commitment GO:0002360 16 7 2,000 5,166E-06 3,187E-04 ! regulation of chemotaxis GO:0050920 40 22 3,000 5,339E-06 3,211E-04 ! response to oxygen levels GO:0070482 176 83 5,000 5,711E-06 3,351E-04 ! positive regulation of cell cycle GO:0045787 89 48 4,000 5,834E-06 3,342E-04 ! negative regulation of growth GO:0045926 155 84 5,000 6,123E-06 3,426E-04 ! regulation of ligase activity GO:0051340 142 84 5,000 6,123E-06 3,348E-04 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 6,436E-06 3,441E-04 GO:0010810|regulation of cell-substrate adhesion, ! regulation of behavior GO:0050795 43 24 3,000 7,691E-06 4,022E-04 ! protein tetramerization GO:0051262 52 24 3,000 7,691E-06 3,937E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 8,233E-06 4,127E-04 ! cellular response to nutrient levels GO:0031669 41 25 3,000 9,117E-06 4,477E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,23E-05 5,92E-04 ! regulation of DNA replication GO:0006275 101 56 4,000 1,257E-05 5,931E-04 ! leukocyte differentiation GO:0002521 202 96 5,000 1,325E-05 6,13E-04 ! establishment of organelle localization GO:0051656 109 59 4,000 1,627E-05 7,385E-04 ! cell cycle arrest GO:0007050 213 100 5,000 1,674E-05 7,458E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 1,75E-05 7,658E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 1,75E-05 7,521E-04 ! response to nicotine GO:0035094 20 10 2,000 1,75E-05 7,389E-04 ! response to heat GO:0009408 50 30 3,000 1,934E-05 8,025E-04 ! regulation of mitosis GO:0007088 105 63 4,000 2,245E-05 9,155E-04 GO:0051783|regulation of nuclear division, ! chondrocyte differentiation GO:0002062 24 11 2,000 2,397E-05 9,614E-04 ! regulation of leukocyte migration GO:0002685 26 11 2,000 2,397E-05 9,456E-04 ! thymus development GO:0048538 27 11 2,000 2,397E-05 9,304E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,397E-05 9,156E-04 GO:0010829|negative regulation of glucose transport, ! positive regulation of cell motion GO:0051272 146 64 4,000 2,425E-05 9,115E-04 ! cell projection assembly GO:0030031 120 66 4,000 2,818E-05 1,043E-03 ! homeostasis of number of cells GO:0048872 114 67 4,000 3,032E-05 1,105E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 3,184E-05 1,143E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 3,184E-05 1,127E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 3,184E-05 1,11E-03 ! focal adhesion formation GO:0048041 35 12 2,000 3,184E-05 1,094E-03 ! T cell homeostasis GO:0043029 25 12 2,000 3,184E-05 1,079E-03 ! negative regulation of ligase activity GO:0051352 112 68 4,000 3,258E-05 1,089E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 4,000 3,258E-05 1,074E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 4,000 3,498E-05 1,137E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 4,000 4,299E-05 1,379E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 4,000 4,299E-05 1,361E-03 ! regulation of protein stability GO:0031647 73 37 3,000 4,528E-05 1,415E-03 ! organelle localization GO:0051640 136 74 4,000 4,907E-05 1,514E-03 ! mitotic cell cycle checkpoint GO:0007093 76 38 3,000 5,04E-05 1,535E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 5,227E-05 1,572E-03 ! response to gamma radiation GO:0010332 28 14 2,000 5,227E-05 1,553E-03 ! catecholamine biosynthetic process GO:0042423 30 14 2,000 5,227E-05 1,534E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 5,227E-05 1,515E-03 ! positive regulation of ligase activity GO:0051351 124 77 4,000 5,942E-05 1,702E-03 ! protein oligomerization GO:0051259 139 78 4,000 6,321E-05 1,789E-03 ! negative regulation of bone remodeling GO:0046851 33 15 2,000 6,508E-05 1,821E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 6,508E-05 1,8E-03 ! lymphocyte homeostasis GO:0002260 30 15 2,000 6,508E-05 1,779E-03 ! T cell differentiation GO:0030217 81 41 3,000 6,829E-05 1,846E-03 ! response to metal ion GO:0010038 140 80 4,000 7,137E-05 1,908E-03 ! cell-substrate adhesion GO:0031589 171 81 4,000 7,574E-05 2,002E-03 ! filopodium assembly GO:0046847 32 16 2,000 7,978E-05 2,086E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 2,000 7,978E-05 2,064E-03 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 8,031E-05 2,056E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 8,253E-05 2,09E-03 ! negative regulation of cell cycle process GO:0010948 32 17 2,000 9,65E-05 2,419E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 9,65E-05 2,394E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 9,65E-05 2,369E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 9,65E-05 2,345E-03 ! mitochondrion organization GO:0007005 148 86 4,000 1,008E-04 2,424E-03 ! response to inorganic substance GO:0010035 153 86 4,000 1,008E-04 2,4E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,153E-04 2,721E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,153E-04 2,694E-03 ! G1 phase GO:0051318 40 19 2,000 1,364E-04 3,156E-03 ! response to temperature stimulus GO:0009266 76 49 3,000 1,382E-04 3,167E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 4,000 1,459E-04 3,312E-03 GO:0010498|proteasomal protein catabolic process, ! response to alkaloid GO:0043279 38 20 2,000 1,599E-04 3,595E-03 ! cellular response to starvation GO:0009267 33 20 2,000 1,599E-04 3,562E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,599E-04 3,529E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 1,599E-04 3,497E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,599E-04 3,466E-03 GO:0010827|regulation of glucose transport, ! negative regulation of translation GO:0017148 29 20 2,000 1,599E-04 3,435E-03 ! positive regulation of growth GO:0045927 90 52 3,000 1,744E-04 3,713E-03 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 1,779E-04 3,754E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 1,858E-04 3,887E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 1,858E-04 3,854E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 2,000 2,143E-04 4,407E-03 ! negative regulation of cell motion GO:0051271 134 55 3,000 2,17E-04 4,424E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 2,455E-04 4,963E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 2,455E-04 4,922E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 2,455E-04 4,881E-03 ! sex determination GO:0007530 47 23 2,000 2,455E-04 4,841E-03 ! platelet activation GO:0030168 37 23 2,000 2,455E-04 4,802E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 2,492E-04 4,836E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 2,794E-04 5,379E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 2,794E-04 5,336E-03 ! leukocyte homeostasis GO:0001776 44 24 2,000 2,794E-04 5,294E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,81E-04 5,282E-03 ! protein maturation by protein folding GO:0022417 13 5 1,000 2,81E-04 5,241E-03 ! apoptotic cell clearance GO:0043277 20 5 1,000 2,81E-04 5,201E-03 ! lipoprotein particle clearance GO:0034381 10 5 1,000 2,81E-04 5,161E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,81E-04 5,122E-03 ! parathyroid gland development GO:0060017 13 5 1,000 2,81E-04 5,084E-03 ! anagen GO:0042640 6 5 1,000 2,81E-04 5,046E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 2,81E-04 5,008E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 2,81E-04 4,972E-03 ! microvillus organization GO:0032528 7 5 1,000 2,81E-04 4,935E-03 GO:0030033|microvillus assembly, ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 2,81E-04 4,9E-03 ! response to food GO:0032094 6 5 1,000 2,81E-04 4,864E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 2,81E-04 4,83E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 2,81E-04 4,795E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 2,81E-04 4,762E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 2,81E-04 4,728E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 2,81E-04 4,695E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,81E-04 4,663E-03 ! regulation of leukocyte degranulation GO:0043300 7 5 1,000 2,81E-04 4,631E-03 ! B cell homeostasis GO:0001782 13 5 1,000 2,81E-04 4,6E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 2,81E-04 4,569E-03 ! porphyrin catabolic process GO:0006787 12 5 1,000 2,81E-04 4,538E-03 GO:0033015|tetrapyrrole catabolic process, ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 2,81E-04 4,508E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,81E-04 4,478E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 2,81E-04 4,448E-03 ! sequestering of calcium ion GO:0051208 7 5 1,000 2,81E-04 4,419E-03 ! stem cell division GO:0017145 11 5 1,000 2,81E-04 4,391E-03 GO:0048103|somatic stem cell division, ! DNA damage response, signal transduction GO:0042770 128 60 3,000 3,039E-04 4,717E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,039E-04 4,687E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 3,163E-04 4,847E-03 ! vasculogenesis GO:0001570 46 25 2,000 3,163E-04 4,817E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 3,163E-04 4,786E-03 ! response to starvation GO:0042594 42 25 2,000 3,163E-04 4,756E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 3,163E-04 4,727E-03 ! interaction with host GO:0051701 62 25 2,000 3,163E-04 4,698E-03 ! molting cycle process GO:0022404 50 26 2,000 3,562E-04 5,257E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 3,562E-04 5,225E-03 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 3,666E-04 5,346E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 3,666E-04 5,314E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 3,991E-04 5,75E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 3,991E-04 5,716E-03 ! mitochondrial membrane organization GO:0007006 57 27 2,000 3,991E-04 5,682E-03 ! male gonad development GO:0008584 44 27 2,000 3,991E-04 5,649E-03 ! germ cell development GO:0007281 118 65 3,000 4,133E-04 5,815E-03 ! myeloid cell differentiation GO:0030099 111 65 3,000 4,133E-04 5,781E-03 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 4,201E-04 5,842E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 1,000 4,201E-04 5,808E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 4,201E-04 5,775E-03 ! male sex determination GO:0030238 15 6 1,000 4,201E-04 5,742E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 4,201E-04 5,71E-03 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 14 6 1,000 4,201E-04 5,678E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 4,201E-04 5,646E-03 ! hair follicle maturation GO:0048820 7 6 1,000 4,201E-04 5,615E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 4,201E-04 5,584E-03 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 1,000 4,201E-04 5,553E-03 ! regulation of mast cell activation GO:0033003 12 6 1,000 4,201E-04 5,523E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 4,201E-04 5,493E-03 ! triglyceride catabolic process GO:0019433 10 6 1,000 4,201E-04 5,463E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 4,201E-04 5,434E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 4,453E-04 5,729E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 4,453E-04 5,698E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 4,453E-04 5,668E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 3,000 4,64E-04 5,876E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 4,91E-04 6,185E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 4,947E-04 6,199E-03 ! catechol metabolic process GO:0009712 54 29 2,000 4,947E-04 6,167E-03 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to organic cyclic substance GO:0014070 55 29 2,000 4,947E-04 6,135E-03 ! urogenital system development GO:0001655 137 69 3,000 5,19E-04 6,404E-03 ! phenol metabolic process GO:0018958 55 30 2,000 5,475E-04 6,721E-03 ! cell junction assembly GO:0034329 78 30 2,000 5,475E-04 6,687E-03 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 5,475E-04 6,653E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 5,475E-04 6,62E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 5,475E-04 6,586E-03 ! reproductive structure development GO:0048608 113 71 3,000 5,785E-04 6,925E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 5,86E-04 6,98E-03 ! prostate gland development GO:0030850 13 7 1,000 5,86E-04 6,946E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 5,86E-04 6,911E-03 ! mRNA stabilization GO:0048255 18 7 1,000 5,86E-04 6,878E-03 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 5,86E-04 6,844E-03 GO:0031958|corticosteroid receptor signaling pathway, ! lipoprotein transport GO:0042953 14 7 1,000 5,86E-04 6,811E-03 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 1,000 5,86E-04 6,779E-03 ! glycerol ether catabolic process GO:0044269 12 7 1,000 5,86E-04 6,746E-03 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 1,000 5,86E-04 6,714E-03 ! spindle checkpoint GO:0031577 15 7 1,000 5,86E-04 6,682E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 5,86E-04 6,651E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 5,86E-04 6,619E-03 ! regulation of meiosis GO:0040020 12 7 1,000 5,86E-04 6,589E-03 GO:0051445|regulation of meiotic cell cycle, ! response to tumor cell GO:0002347 13 7 1,000 5,86E-04 6,558E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 5,86E-04 6,528E-03 ! negative regulation of nuclear division GO:0051784 14 7 1,000 5,86E-04 6,497E-03 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 1,000 5,86E-04 6,468E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 5,86E-04 6,438E-03 ! muscle adaptation GO:0043500 14 7 1,000 5,86E-04 6,409E-03 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 6,038E-04 6,573E-03 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 6,1E-04 6,611E-03 ! response to hydrogen peroxide GO:0042542 50 32 2,000 6,637E-04 7,16E-03 ! metanephros development GO:0001656 74 32 2,000 6,637E-04 7,128E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 6,637E-04 7,097E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 6,637E-04 7,065E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 6,637E-04 7,034E-03 ! regulation of transcription factor activity GO:0051090 126 74 3,000 6,767E-04 7,141E-03 GO:0090046|regulation of transcription regulator activity, ! cell-matrix adhesion GO:0007160 163 75 3,000 7,118E-04 7,479E-03 ! regulation of vesicle-mediated transport GO:0060627 119 75 3,000 7,118E-04 7,446E-03 ! lymphocyte differentiation GO:0030098 167 75 3,000 7,118E-04 7,414E-03 ! DNA damage checkpoint GO:0000077 71 33 2,000 7,272E-04 7,541E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 7,272E-04 7,509E-03 GO:0060326|cell chemotaxis, ! neutral lipid catabolic process GO:0046461 13 8 1,000 7,786E-04 8,006E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 7,786E-04 7,972E-03 ! glycerolipid catabolic process GO:0046503 13 8 1,000 7,786E-04 7,938E-03 ! pigment granule organization GO:0048753 16 8 1,000 7,786E-04 7,904E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 7,786E-04 7,871E-03 ! ER overload response GO:0006983 12 8 1,000 7,786E-04 7,838E-03 ! regulation of pigmentation during development GO:0048070 24 8 1,000 7,786E-04 7,806E-03 ! melanin metabolic process GO:0006582 15 8 1,000 7,786E-04 7,773E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,786E-04 7,741E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 7,786E-04 7,709E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 7,786E-04 7,678E-03 ! positive regulation of vasodilation GO:0045909 13 8 1,000 7,786E-04 7,646E-03 ! negative regulation of translational initiation GO:0045947 10 8 1,000 7,786E-04 7,615E-03 ! response to UV-B GO:0010224 16 8 1,000 7,786E-04 7,584E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 7,786E-04 7,554E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 7,786E-04 7,523E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 7,786E-04 7,493E-03 ! mast cell activation GO:0045576 14 8 1,000 7,786E-04 7,463E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 7,786E-04 7,434E-03 ! positive regulation of endocytosis GO:0045807 50 34 2,000 7,944E-04 7,555E-03 ! biogenic amine biosynthetic process GO:0042401 62 34 2,000 7,944E-04 7,525E-03 ! placenta development GO:0001890 53 34 2,000 7,944E-04 7,496E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 7,944E-04 7,466E-03 ! blood coagulation GO:0007596 146 78 3,000 8,251E-04 7,724E-03 GO:0050817|coagulation, ! positive regulation of phosphorylation GO:0042327 129 79 3,000 8,655E-04 8,071E-03 ! cell junction organization GO:0034330 86 36 2,000 9,405E-04 8,737E-03 ! DNA integrity checkpoint GO:0031570 75 36 2,000 9,405E-04 8,703E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 9,405E-04 8,67E-03 ! negative regulation of cell activation GO:0050866 65 36 2,000 9,405E-04 8,637E-03 ! T cell activation GO:0042110 168 81 3,000 9,505E-04 8,696E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 9,505E-04 8,663E-03 GO:0045937|positive regulation of phosphate metabolic process, ! response to nutrient GO:0007584 125 82 3,000 9,951E-04 9,035E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 9,975E-04 9,023E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 9,975E-04 8,989E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 9,975E-04 8,956E-03 ! T cell selection GO:0045058 23 9 1,000 9,975E-04 8,922E-03 ! behavioral fear response GO:0001662 22 9 1,000 9,975E-04 8,889E-03 GO:0002209|behavioral defense response, ! protein heterooligomerization GO:0051291 16 9 1,000 9,975E-04 8,856E-03 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 9,975E-04 8,824E-03 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 9,975E-04 8,792E-03 ! synaptic vesicle endocytosis GO:0048488 20 9 1,000 9,975E-04 8,759E-03 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 9,975E-04 8,728E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 1,019E-03 8,887E-03 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,019E-03 8,855E-03 ! pigment metabolic process GO:0042440 80 37 2,000 1,019E-03 8,823E-03 ! hemostasis GO:0007599 158 84 3,000 1,089E-03 9,389E-03 ! negative regulation of transport GO:0051051 153 84 3,000 1,089E-03 9,356E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 1,103E-03 9,44E-03 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,103E-03 9,407E-03 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 64 38 2,000 1,103E-03 9,374E-03 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 1,19E-03 0,01007957 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,243E-03 0,0104898 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 1,243E-03 0,01045312 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,243E-03 0,0104167 ! lung alveolus development GO:0048286 26 10 1,000 1,243E-03 0,01038053 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 1,243E-03 0,01034461 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,243E-03 0,01030894 GO:0005978|glycogen biosynthetic process, ! B cell proliferation GO:0042100 18 10 1,000 1,243E-03 0,01027352 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,243E-03 0,01023833 ! regulation of bone resorption GO:0045124 25 10 1,000 1,243E-03 0,01020339 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,243E-03 0,01016869 ! positive regulation of phagocytosis GO:0050766 13 10 1,000 1,243E-03 0,01013422 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,243E-03 0,01009998 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,243E-03 0,01006597 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 1,243E-03 0,01003219 ! negative regulation of immune effector process GO:0002698 20 10 1,000 1,243E-03 9,999E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,243E-03 9,965E-03 ! negative regulation of binding GO:0051100 72 40 2,000 1,281E-03 0,01024129 ! positive regulation of protein modification process GO:0031401 136 88 3,000 1,294E-03 0,0103115 ! regulation of DNA binding GO:0051101 155 88 3,000 1,294E-03 0,01027746 ! gland development GO:0048732 206 88 3,000 1,294E-03 0,01024366 ! regulation of cell adhesion GO:0030155 212 89 3,000 1,35E-03 0,01064653 ! sex differentiation GO:0007548 145 90 3,000 1,407E-03 0,0110596 ! response to protein stimulus GO:0051789 149 91 3,000 1,465E-03 0,01148295 ! response to reactive oxygen species GO:0000302 67 42 2,000 1,477E-03 0,01153883 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 1,513E-03 0,01178359 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,513E-03 0,01174558 ! blood vessel remodeling GO:0001974 29 11 1,000 1,513E-03 0,01170781 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,513E-03 0,01167029 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,513E-03 0,011633 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,513E-03 0,01159595 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,513E-03 0,01155914 ! negative regulation of ossification GO:0030279 26 11 1,000 1,513E-03 0,01152256 ! nitric oxide mediated signal transduction GO:0007263 23 11 1,000 1,513E-03 0,01148621 ! oocyte differentiation GO:0009994 18 11 1,000 1,513E-03 0,01145009 ! sequestering of metal ion GO:0051238 14 11 1,000 1,513E-03 0,0114142 ! regulation of embryonic development GO:0045995 27 11 1,000 1,513E-03 0,01137853 ! negative regulation of multicellular organismal process GO:0051241 166 93 3,000 1,587E-03 0,01189882 ! male sex differentiation GO:0046661 76 44 2,000 1,691E-03 0,01263404 ! B cell differentiation GO:0030183 107 44 2,000 1,691E-03 0,01259492 ! developmental growth GO:0048589 82 44 2,000 1,691E-03 0,01255605 ! leukocyte migration GO:0050900 68 45 2,000 1,805E-03 0,01335926 ! cell growth GO:0016049 84 45 2,000 1,805E-03 0,01331829 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 1,81E-03 0,01331509 ! virus-host interaction GO:0019048 29 12 1,000 1,81E-03 0,01327449 ! entry into host cell GO:0030260 32 12 1,000 1,81E-03 0,01323415 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 1,000 1,81E-03 0,01319404 ! protein homotetramerization GO:0051289 21 12 1,000 1,81E-03 0,01315418 ! regulation of phagocytosis GO:0050764 16 12 1,000 1,81E-03 0,01311456 ! histone acetylation GO:0016573 26 12 1,000 1,81E-03 0,01307518 ! gland morphogenesis GO:0022612 29 12 1,000 1,81E-03 0,01303603 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,81E-03 0,01299712 ! spleen development GO:0048536 22 12 1,000 1,81E-03 0,01295843 ! digestive tract morphogenesis GO:0048546 26 12 1,000 1,81E-03 0,01291998 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,81E-03 0,01288176 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,81E-03 0,01284376 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 1,923E-03 0,0136076 ! negative regulation of cell migration GO:0030336 115 46 2,000 1,923E-03 0,01356769 ! pigmentation GO:0043473 100 46 2,000 1,923E-03 0,01352802 ! positive regulation of defense response GO:0031349 76 47 2,000 2,046E-03 0,01435215 ! response to calcium ion GO:0051592 81 47 2,000 2,046E-03 0,01431043 ! protein homooligomerization GO:0051260 76 47 2,000 2,046E-03 0,01426895 ! regulation of chemokine production GO:0032642 18 13 1,000 2,131E-03 0,01481977 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,131E-03 0,01477706 ! response to X-ray GO:0010165 25 13 1,000 2,131E-03 0,0147346 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,131E-03 0,01469238 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,131E-03 0,0146504 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 2,131E-03 0,01460866 ! regulation of cytokine production during immune response GO:0002718 23 13 1,000 2,131E-03 0,01456716 ! regulation of cellular pH GO:0030641 22 13 1,000 2,131E-03 0,01452589 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,131E-03 0,01448486 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,131E-03 0,01444406 ! mitochondrial transport GO:0006839 82 48 2,000 2,174E-03 0,0146925 ! cellular component disassembly GO:0022411 86 48 2,000 2,174E-03 0,01465135 ! activation of caspase activity GO:0006919 84 48 2,000 2,174E-03 0,01461042 ! regulation of inflammatory response GO:0050727 75 48 2,000 2,174E-03 0,01456973 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,174E-03 0,01452925 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,307E-03 0,01537387 ! regulation of cell projection organization GO:0031344 121 50 2,000 2,444E-03 0,01624654 ! negative regulation of immune system process GO:0002683 95 50 2,000 2,444E-03 0,01620178 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,478E-03 0,01637716 ! hair follicle morphogenesis GO:0031069 26 14 1,000 2,478E-03 0,01633229 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 2,478E-03 0,01628767 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 2,478E-03 0,01624329 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 31 14 1,000 2,478E-03 0,01619915 ! regulation of RNA stability GO:0043487 32 14 1,000 2,478E-03 0,01615525 ! response to estrogen stimulus GO:0043627 93 51 2,000 2,587E-03 0,01682302 ! vesicle organization GO:0016050 107 51 2,000 2,587E-03 0,01677767 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 2,587E-03 0,01673257 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 2,000 2,735E-03 0,01764053 ! regulation of muscle contraction GO:0006937 81 52 2,000 2,735E-03 0,01759337 ! cartilage development GO:0051216 90 52 2,000 2,735E-03 0,01754645 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 2,849E-03 0,01822957 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 2,849E-03 0,01818122 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 2,849E-03 0,01813312 ! regulation of exocytosis GO:0017157 22 15 1,000 2,849E-03 0,01808528 ! G1/S transition checkpoint GO:0031575 40 15 1,000 2,849E-03 0,01803768 ! regulation of vasodilation GO:0042312 26 15 1,000 2,849E-03 0,01799034 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,849E-03 0,01794324 ! regulation of translational initiation GO:0006446 82 53 2,000 2,888E-03 0,01813994 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 2,888E-03 0,0180927 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 2,000 3,046E-03 0,01903294 ! positive regulation of caspase activity GO:0043280 95 55 2,000 3,209E-03 0,02000081 GO:0010952|positive regulation of peptidase activity, ! regulation of multicellular organism growth GO:0040014 85 55 2,000 3,209E-03 0,01994913 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,244E-03 0,02011878 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 3,244E-03 0,02006706 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 3,244E-03 0,0200156 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,244E-03 0,01996441 ! defense response to virus GO:0051607 37 16 1,000 3,244E-03 0,01991348 ! regulation of bone remodeling GO:0046850 137 57 2,000 3,551E-03 0,02173977 ! metencephalon development GO:0022037 30 17 1,000 3,664E-03 0,02237548 ! regulation of viral genome replication GO:0045069 28 17 1,000 3,664E-03 0,02231883 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 3,664E-03 0,02226247 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,664E-03 0,0222064 ! regulation of protein binding GO:0043393 33 17 1,000 3,664E-03 0,0221506 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 3,664E-03 0,02209509 ! regulation of tissue remodeling GO:0034103 140 58 2,000 3,73E-03 0,02243691 ! regulation of endocytosis GO:0030100 91 58 2,000 3,73E-03 0,02238096 ! regulation of heart contraction GO:0008016 110 60 2,000 4,105E-03 0,0245674 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 4,105E-03 0,02450643 ! kidney development GO:0001822 122 60 2,000 4,105E-03 0,02444578 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 4,108E-03 0,02440307 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,108E-03 0,02434296 ! positive regulation of proteolysis GO:0045862 31 18 1,000 4,108E-03 0,02428315 ! epidermis morphogenesis GO:0048730 40 18 1,000 4,108E-03 0,02422363 ! response to retinoic acid GO:0032526 26 18 1,000 4,108E-03 0,02416441 ! long-chain fatty acid transport GO:0015909 31 18 1,000 4,108E-03 0,02410547 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 4,108E-03 0,02404682 ! regulation of protein complex assembly GO:0043254 117 61 2,000 4,3E-03 0,02511316 ! viral reproductive process GO:0022415 126 62 2,000 4,501E-03 0,02622408 ! gonad development GO:0008406 98 62 2,000 4,501E-03 0,02616073 ! regulation of homeostatic process GO:0032844 134 62 2,000 4,501E-03 0,02609769 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 4,575E-03 0,02645999 ! lipid phosphorylation GO:0046834 35 19 1,000 4,575E-03 0,02639654 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 4,575E-03 0,02633339 ! pigmentation during development GO:0048066 41 19 1,000 4,575E-03 0,02627054 ! cellular response to unfolded protein GO:0034620 33 19 1,000 4,575E-03 0,02620799 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 1,000 4,575E-03 0,02614574 ! heme metabolic process GO:0042168 36 19 1,000 4,575E-03 0,02608378 ! actin filament bundle formation GO:0051017 42 19 1,000 4,575E-03 0,02602212 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 4,575E-03 0,02596075 ! protein export from nucleus GO:0006611 36 19 1,000 4,575E-03 0,02589966 ! cellular pigmentation GO:0033059 36 19 1,000 4,575E-03 0,02583887 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 4,575E-03 0,02577835 ! protein amino acid acetylation GO:0006473 39 20 1,000 5,066E-03 0,02847583 ! response to vitamin GO:0033273 31 20 1,000 5,066E-03 0,02840945 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 5,066E-03 0,02834338 GO:0010675|regulation of cellular carbohydrate metabolic process, ! negative regulation of T cell activation GO:0050868 40 20 1,000 5,066E-03 0,02827762 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 5,066E-03 0,02821216 ! actin filament organization GO:0007015 148 66 2,000 5,363E-03 0,02979745 ! developmental maturation GO:0021700 116 66 2,000 5,363E-03 0,02972879 ! ovarian follicle development GO:0001541 35 21 1,000 5,579E-03 0,03085864 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 5,579E-03 0,03078787 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 5,579E-03 0,03071741 ! oogenesis GO:0048477 36 21 1,000 5,579E-03 0,03064728 ! response to cytokine stimulus GO:0034097 63 21 1,000 5,579E-03 0,03057747 ! gut development GO:0048565 39 21 1,000 5,579E-03 0,03050798 ! lung development GO:0030324 144 67 2,000 5,592E-03 0,03050966 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 5,592E-03 0,03044063 ! viral reproduction GO:0016032 134 68 2,000 5,828E-03 0,03165063 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 6,116E-03 0,03314032 ! regeneration GO:0031099 41 22 1,000 6,116E-03 0,03306585 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 6,116E-03 0,03299171 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 6,116E-03 0,0329179 ! apoptotic nuclear changes GO:0030262 32 22 1,000 6,116E-03 0,03284442 ! ureteric bud development GO:0001657 43 22 1,000 6,116E-03 0,03277127 ! renal system process GO:0003014 41 22 1,000 6,116E-03 0,03269845 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 6,116E-03 0,03262595 ! positive regulation of B cell activation GO:0050871 38 22 1,000 6,116E-03 0,03255377 ! protein stabilization GO:0050821 39 22 1,000 6,116E-03 0,0324819 ! respiratory tube development GO:0030323 150 70 2,000 6,316E-03 0,03347257 ! B cell activation GO:0042113 160 71 2,000 6,569E-03 0,03473753 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,675E-03 0,03521802 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 6,675E-03 0,03514095 ! response to ethanol GO:0045471 46 23 1,000 6,675E-03 0,03506423 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 6,675E-03 0,03498783 ! regulation of viral reproduction GO:0050792 38 23 1,000 6,675E-03 0,03491177 ! synaptic vesicle transport GO:0048489 46 23 1,000 6,675E-03 0,03483604 ! fatty acid transport GO:0015908 44 23 1,000 6,675E-03 0,03476064 ! negative regulation of cytokine production GO:0001818 40 23 1,000 6,675E-03 0,03468556 ! regulation of caspase activity GO:0043281 122 72 2,000 6,828E-03 0,03540724 ! respiratory system development GO:0060541 153 72 2,000 6,828E-03 0,03533109 ! learning or memory GO:0007611 147 73 2,000 7,093E-03 0,03662399 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 7,256E-03 0,03738382 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 7,256E-03 0,03730394 ! regulation of transmembrane transport GO:0034762 38 24 1,000 7,256E-03 0,0372244 ! multicellular organismal response to stress GO:0033555 49 24 1,000 7,256E-03 0,0371452 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 7,256E-03 0,03706633 ! lymphocyte proliferation GO:0046651 48 24 1,000 7,256E-03 0,0369878 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 7,256E-03 0,0369096 ! porphyrin metabolic process GO:0006778 46 24 1,000 7,256E-03 0,03683173 GO:0033013|tetrapyrrole metabolic process, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 7,365E-03 0,03730341 ! negative regulation of DNA replication GO:0008156 42 25 1,000 7,86E-03 0,03972726 ! negative regulation of cell development GO:0010721 73 25 1,000 7,86E-03 0,03964397 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 7,86E-03 0,03956103 ! liver development GO:0001889 53 25 1,000 7,86E-03 0,03947844 ! development of primary sexual characteristics GO:0045137 124 76 2,000 7,925E-03 0,03972429 ! regulation of catabolic process GO:0009894 161 76 2,000 7,925E-03 0,03964171 ! initiation of viral infection GO:0019059 57 26 1,000 8,485E-03 0,04235397 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 8,485E-03 0,04226628 ! macromolecular complex disassembly GO:0032984 53 26 1,000 8,485E-03 0,04217895 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 8,485E-03 0,04209198 ! cellular response to oxidative stress GO:0034599 39 26 1,000 8,485E-03 0,04200537 ! positive regulation of nuclear division GO:0051785 40 26 1,000 8,485E-03 0,04191912 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 52 26 1,000 8,485E-03 0,04183322 GO:0032943|mononuclear cell proliferation, ! negative regulation of organelle organization GO:0010639 161 78 2,000 8,51E-03 0,04187149 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 8,51E-03 0,04178603 ! regulation of peptidase activity GO:0052547 134 79 2,000 8,812E-03 0,0431796 ! protein import into nucleus GO:0006606 158 80 2,000 9,12E-03 0,04459787 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 9,132E-03 0,04456584 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 9,132E-03 0,04447563 ! protein amino acid acylation GO:0043543 55 27 1,000 9,132E-03 0,04438578 ! fat cell differentiation GO:0045444 50 27 1,000 9,132E-03 0,04429629 ! response to toxin GO:0009636 47 27 1,000 9,132E-03 0,04420716 ! base-excision repair GO:0006284 41 27 1,000 9,132E-03 0,04411839 ! regulation of chromosome organization GO:0033044 42 27 1,000 9,132E-03 0,04402998 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 9,132E-03 0,04394192 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 9,132E-03 0,04385421 ! nuclear import GO:0051170 161 81 2,000 9,434E-03 0,04521538 ! regulation of neuron differentiation GO:0045664 167 81 2,000 9,434E-03 0,04512549 ! response to drug GO:0042493 143 82 2,000 9,754E-03 0,04656578 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 9,8E-03 0,04669035 ! regulation of pH GO:0006885 43 29 1,000 0,01048921 0,04987555 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 0,01048921 0,04977717 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01048921 0,04967919 ! tissue homeostasis GO:0001894 48 29 1,000 0,01048921 0,04958159 GO:0048871|multicellular organismal homeostasis, ! response to unfolded protein GO:0006986 131 85 2,000 0,0107536 0,05073171 ! amine biosynthetic process GO:0009309 138 86 2,000 0,01109933 0,05226027 ! cofactor catabolic process GO:0051187 51 30 1,000 0,01119933 0,05262809 ! protein localization in nucleus GO:0034504 176 87 2,000 0,01145143 0,05370789 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01193005 0,05584379 ! ovulation cycle process GO:0022602 49 31 1,000 0,01193005 0,05573535 ! triglyceride metabolic process GO:0006641 43 31 1,000 0,01193005 0,05562734 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01193005 0,05551974 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01193005 0,05541256 ! myeloid leukocyte activation GO:0002274 49 31 1,000 0,01193005 0,05530579 ! cholesterol transport GO:0030301 56 32 1,000 0,01268115 0,05867469 ! spindle organization GO:0007051 46 32 1,000 0,01268115 0,05856207 ! regulation of ARF GTPase activity GO:0032312 65 32 1,000 0,01268115 0,05844988 ! ovulation cycle GO:0042698 51 32 1,000 0,01268115 0,05833812 ! hindbrain development GO:0030902 61 32 1,000 0,01268115 0,05822679 ! regulation of defense response GO:0031347 149 92 2,000 0,01330811 0,06098915 ! post-embryonic development GO:0009791 69 33 1,000 0,01345237 0,06153309 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01345237 0,06141633 ! sterol transport GO:0015918 57 33 1,000 0,01345237 0,06130001 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 0,01369879 0,06230491 ! biogenic amine metabolic process GO:0006576 155 94 2,000 0,01409597 0,06399037 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,01424349 0,06453831 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01424349 0,064417 ! regulation of muscle development GO:0048634 70 35 1,000 0,01505428 0,06795609 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01505428 0,06782883 ! negative regulation of secretion GO:0051048 63 35 1,000 0,01505428 0,06770205 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01505428 0,06757574 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01505428 0,0674499 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01505428 0,06732453 ! female gonad development GO:0008585 58 35 1,000 0,01505428 0,06719962 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,01505428 0,06707518 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01505428 0,06695119 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,0158845 0,07051312 ! positive regulation of cell development GO:0010720 80 36 1,000 0,0158845 0,07038326 ! regulation of proteolysis GO:0030162 72 36 1,000 0,0158845 0,07025388 ! meiosis I GO:0007127 65 37 1,000 0,01673393 0,07387493 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01673393 0,07373963 ! tissue remodeling GO:0048771 76 37 1,000 0,01673393 0,07360482 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01673393 0,07347051 ! glycerol ether metabolic process GO:0006662 53 37 1,000 0,01673393 0,07333668 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01673393 0,07320334 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01760234 0,07686249 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,01760234 0,07672325 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01760234 0,07658451 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,01760234 0,07644627 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 1,000 0,01848951 0,08015451 ! organic ether metabolic process GO:0018904 55 39 1,000 0,01848951 0,08001035 ! segmentation GO:0035282 67 39 1,000 0,01848951 0,0798667 ! mesenchymal cell development GO:0014031 87 40 1,000 0,01939521 0,08362879 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 1,000 0,01939521 0,08347918 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02031922 0,08730006 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,02031922 0,08714445 ! female gamete generation GO:0007292 61 41 1,000 0,02031922 0,08698939 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02126132 0,09086099 GO:0090047|positive regulation of transcription regulator activity, ! monocarboxylic acid transport GO:0015718 85 42 1,000 0,02126132 0,09069989 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,02126132 0,09053936 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02126132 0,0903794 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,0222213 0,09429357 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,0222213 0,09412756 ! glucose transport GO:0015758 65 43 1,000 0,0222213 0,09396213 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,0222213 0,09379728 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,0222213 0,09363302 ! phagocytosis GO:0006909 90 43 1,000 0,0222213 0,09346932 ! hexose transport GO:0008645 67 44 1,000 0,02319894 0,09741127 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 1,000 0,02319894 0,09724156 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,02419403 0,10123624 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,02419403 0,10106048 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,02419403 0,10088533 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,0262357 0,10920951 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,0262357 0,10902089 ! JNK cascade GO:0007254 91 47 1,000 0,0262357 0,10883292 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02644657 0,10951886 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02644657 0,10933068 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02644657 0,10914315 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02644657 0,10895626 ! neuron fate determination GO:0048664 7 5 0,000 0,02644657 0,10877001 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02644657 0,1085844 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02644657 0,10839941 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02644657 0,10821506 ! polyol transport GO:0015791 12 5 0,000 0,02644657 0,10803133 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02644657 0,10784823 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02644657 0,10766575 ! response to superoxide GO:0000303 10 5 0,000 0,02644657 0,10748388 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02644657 0,10730262 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02644657 0,10712198 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02644657 0,10694194 ! female meiosis GO:0007143 7 5 0,000 0,02644657 0,10676251 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02644657 0,10658368 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02644657 0,10640544 ! cobalt ion transport GO:0006824 11 5 0,000 0,02644657 0,10622781 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02644657 0,10605076 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02644657 0,1058743 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02644657 0,10569843 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02644657 0,10552314 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02644657 0,10534844 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02644657 0,10517431 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02644657 0,10500075 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02644657 0,10482777 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02644657 0,10465535 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02644657 0,10448351 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02644657 0,10431222 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02644657 0,1041415 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02644657 0,10397133 ! negative chemotaxis GO:0050919 14 5 0,000 0,02644657 0,10380172 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02644657 0,10363266 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02644657 0,10346416 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02644657 0,10329619 ! behavioral response to pain GO:0048266 9 5 0,000 0,02644657 0,10312878 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02644657 0,1029619 ! Notch receptor processing GO:0007220 8 5 0,000 0,02644657 0,10279557 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02644657 0,10262977 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02644657 0,1024645 ! micturition GO:0060073 9 5 0,000 0,02644657 0,10229977 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02644657 0,10213556 ! copulation GO:0007620 9 5 0,000 0,02644657 0,10197188 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02644657 0,10180873 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02644657 0,1016461 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02644657 0,10148398 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02644657 0,10132238 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02644657 0,1011613 ! grooming behavior GO:0007625 6 5 0,000 0,02644657 0,10100072 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02644657 0,10084066 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02644657 0,1006811 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02644657 0,10052205 ! response to protozoan GO:0001562 10 5 0,000 0,02644657 0,10036349 ! lymph vessel development GO:0001945 10 5 0,000 0,02644657 0,10020544 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02644657 0,10004789 ! endochondral ossification GO:0001958 16 5 0,000 0,02644657 0,09989082 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02644657 0,09973426 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02644657 0,09957818 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02644657 0,09942259 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02644657 0,09926748 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02644657 0,09911286 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02644657 0,09895872 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02644657 0,09880506 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02644657 0,09865187 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02644657 0,09849916 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02644657 0,09834692 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02644657 0,09819515 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02644657 0,09804385 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02644657 0,09789301 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02644657 0,09774264 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02644657 0,09759272 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02644657 0,09744327 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02644657 0,09729427 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02644657 0,09714573 ! histidine catabolic process GO:0006548 6 5 0,000 0,02644657 0,09699765 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02644657 0,09685001 ! valine metabolic process GO:0006573 10 5 0,000 0,02644657 0,09670282 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02644657 0,09655608 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02644657 0,09640978 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02644657 0,09626393 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02644657 0,09611851 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02644657 0,09597354 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02644657 0,095829 ! polyol catabolic process GO:0046174 7 5 0,000 0,02644657 0,0956849 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02644657 0,09554122 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02644657 0,09539798 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02644657 0,09525517 ! muscle cell migration GO:0014812 8 5 0,000 0,02644657 0,09511279 ! mitochondrial fission GO:0000266 8 5 0,000 0,02644657 0,09497083 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02644657 0,09482929 ! mRNA transcription GO:0009299 9 5 0,000 0,02644657 0,09468818 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02644657 0,09454748 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02644657 0,0944072 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02644657 0,09426734 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02644657 0,09412789 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02644657 0,09398886 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02644657 0,09385023 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02644657 0,09371201 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02644657 0,0935742 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02644657 0,09343679 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02644657 0,09329979 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02644657 0,09316319 ! forebrain neuron development GO:0021884 13 5 0,000 0,02644657 0,09302698 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02644657 0,09289118 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02644657 0,09275577 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02644657 0,09262075 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02644657 0,09248613 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02644657 0,09235189 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02644657 0,09221805 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02644657 0,0920846 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02644657 0,09195153 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02644657 0,09181884 ! basic amino acid transport GO:0015802 11 5 0,000 0,02644657 0,09168654 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02644657 0,09155461 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02644657 0,09142307 ! depyrimidination GO:0045008 10 5 0,000 0,02644657 0,0912919 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02644657 0,09116111 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02644657 0,09103069 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02644657 0,09090065 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02644657 0,09077098 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02644657 0,09064167 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02644657 0,09051274 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02644657 0,09038417 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02644657 0,09025597 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02644657 0,09012812 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02644657 0,09000064 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02644657 0,08987352 ! response to arsenic GO:0046685 10 5 0,000 0,02644657 0,08974676 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02644657 0,08962036 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02644657 0,08949431 GO:0002448|mast cell mediated immunity, ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02644657 0,08936862 ! response to cadmium ion GO:0046686 7 5 0,000 0,02644657 0,08924328 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02644657 0,08911829 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02644657 0,08899364 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02644657 0,08886935 ! decidualization GO:0046697 11 5 0,000 0,02644657 0,08874541 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02644657 0,0886218 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02644657 0,08849855 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02644657 0,08837563 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02644657 0,08825306 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02644657 0,08813082 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02644657 0,08800893 ! neural tube patterning GO:0021532 7 5 0,000 0,02644657 0,08788737 ! embryonic cleavage GO:0040016 6 5 0,000 0,02644657 0,08776615 ! peroxisome fission GO:0016559 5 5 0,000 0,02644657 0,08764526 ! histone demethylation GO:0016577 10 5 0,000 0,02644657 0,0875247 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02644657 0,08740447 ! mitotic recombination GO:0006312 9 5 0,000 0,02644657 0,08728458 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02644657 0,08716501 ! metaphase plate congression GO:0051310 7 5 0,000 0,02644657 0,08704577 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02644657 0,08692685 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02644657 0,08680826 ! enteric nervous system development GO:0048484 8 5 0,000 0,02644657 0,08668999 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02644657 0,08657205 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02644657 0,08645442 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02644657 0,08633712 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02644657 0,08622013 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02644657 0,08610346 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02644657 0,0859871 ! plasminogen activation GO:0031639 5 5 0,000 0,02644657 0,08587106 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02644657 0,08575533 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02644657 0,08563991 ! metaphase GO:0051323 8 5 0,000 0,02644657 0,08552481 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02644657 0,08541001 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02644657 0,08529552 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02644657 0,08518133 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02644657 0,08506745 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02644657 0,08495388 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02644657 0,08484061 ! response to redox state GO:0051775 5 5 0,000 0,02644657 0,08472764 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02644657 0,08461497 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02644657 0,0845026 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02644657 0,08439052 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02644657 0,08427875 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02644657 0,08416727 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02644657 0,08405608 ! circadian behavior GO:0048512 13 5 0,000 0,02644657 0,08394519 ! striatum development GO:0021756 9 5 0,000 0,02644657 0,08383459 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02644657 0,08372428 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02644657 0,08361426 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02644657 0,08350453 ! glial cell migration GO:0008347 11 5 0,000 0,02644657 0,08339509 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02644657 0,08328594 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02644657 0,08317707 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02644657 0,08306848 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02644657 0,08296018 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02644657 0,08285216 ! neuroprotection GO:0043526 6 5 0,000 0,02644657 0,08274442 ! neural plate development GO:0001840 8 5 0,000 0,02644657 0,08263696 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02644657 0,08252977 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02644657 0,08242287 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02644657 0,08231624 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02644657 0,08220989 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02644657 0,08210381 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02644657 0,08199801 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02644657 0,08189248 ! spindle assembly GO:0051225 6 5 0,000 0,02644657 0,08178722 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02644657 0,08168223 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02644657 0,08157751 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02644657 0,08147305 ! drug metabolic process GO:0017144 6 5 0,000 0,02644657 0,08136887 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02644657 0,08126495 ! organ regeneration GO:0031100 7 5 0,000 0,02644657 0,0811613 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02644657 0,08105791 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02644657 0,08095478 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02644657 0,08085191 ! regulation of ARF protein signal transduction GO:0032012 102 48 1,000 0,02728186 0,0832997 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,02728186 0,08319412 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,02834464 0,08632556 ! endocrine system development GO:0035270 104 49 1,000 0,02834464 0,08621643 ! regulation of ossification GO:0030278 117 50 1,000 0,02942381 0,08938597 ! histone modification GO:0016570 91 50 1,000 0,02942381 0,08927325 ! positive regulation of binding GO:0051099 78 51 1,000 0,03051919 0,09248006 ! viral infectious cycle GO:0019058 99 51 1,000 0,03051919 0,09236373 ! excretion GO:0007588 83 51 1,000 0,03051919 0,0922477 ! regulation of cell shape GO:0008360 125 51 1,000 0,03051919 0,09213195 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,03051919 0,0920165 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03163056 0,09524798 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,03163056 0,09512892 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03165188 0,09507418 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03165188 0,09495563 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03165188 0,09483738 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03165188 0,09471942 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03165188 0,09460176 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03165188 0,09448439 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03165188 0,09436731 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03165188 0,09425051 ! sleep GO:0030431 13 6 0,000 0,03165188 0,09413401 ! response to oxygen radical GO:0000305 11 6 0,000 0,03165188 0,0940178 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03165188 0,09390187 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03165188 0,09378623 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03165188 0,09367087 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03165188 0,09355579 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03165188 0,093441 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03165188 0,09332649 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03165188 0,09321226 ! forebrain regionalization GO:0021871 8 6 0,000 0,03165188 0,09309831 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03165188 0,09298463 ! male meiosis GO:0007140 7 6 0,000 0,03165188 0,09287124 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03165188 0,09275812 ! response to zinc ion GO:0010043 9 6 0,000 0,03165188 0,09264527 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03165188 0,0925327 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03165188 0,09242041 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03165188 0,09230838 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03165188 0,09219663 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03165188 0,09208515 ! malate metabolic process GO:0006108 11 6 0,000 0,03165188 0,09197393 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03165188 0,09186299 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03165188 0,09175231 ! protein refolding GO:0042026 15 6 0,000 0,03165188 0,0916419 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03165188 0,09153175 ! opsonization GO:0008228 8 6 0,000 0,03165188 0,09142187 ! mating behavior GO:0007617 7 6 0,000 0,03165188 0,09131225 ! neuron remodeling GO:0016322 15 6 0,000 0,03165188 0,09120289 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03165188 0,0910938 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03165188 0,09098497 ! equilibrioception GO:0050957 14 6 0,000 0,03165188 0,09087639 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03165188 0,09076808 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03165188 0,09066002 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03165188 0,09055222 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03165188 0,09044467 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03165188 0,09033739 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03165188 0,09023035 ! toxin metabolic process GO:0009404 11 6 0,000 0,03165188 0,09012357 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03165188 0,09001704 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03165188 0,08991076 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03165188 0,08980474 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03165188 0,08969896 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03165188 0,08959343 ! thymic T cell selection GO:0045061 12 6 0,000 0,03165188 0,08948815 ! protein lipoylation GO:0009249 10 6 0,000 0,03165188 0,08938312 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03165188 0,08927833 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03165188 0,08917379 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03165188 0,08906949 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03165188 0,08896544 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03165188 0,08886163 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03165188 0,08875806 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03165188 0,08865473 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03165188 0,08855165 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03165188 0,0884488 ! hyperosmotic response GO:0006972 9 6 0,000 0,03165188 0,08834619 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03165188 0,08824382 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03165188 0,08814169 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03165188 0,08803979 ! urea metabolic process GO:0019627 7 6 0,000 0,03165188 0,08793812 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03165188 0,0878367 ! neutrophil activation GO:0042119 8 6 0,000 0,03165188 0,0877355 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03165188 0,08763454 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03165188 0,08753381 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03165188 0,08743331 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03165188 0,08733305 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03165188 0,08723301 ! neuron apoptosis GO:0051402 9 6 0,000 0,03165188 0,0871332 ! nucleoside salvage GO:0043174 9 6 0,000 0,03165188 0,08703362 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03165188 0,08693426 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03165188 0,08683514 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03165188 0,08673624 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03165188 0,08663756 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03165188 0,08653911 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03165188 0,08644088 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03165188 0,08634288 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03165188 0,08624509 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03165188 0,08614753 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03165188 0,08605019 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03165188 0,08595307 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03165188 0,08585616 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03165188 0,08575948 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03165188 0,08566301 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03165188 0,08556676 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03165188 0,08547072 ! response to UV-C GO:0010225 11 6 0,000 0,03165188 0,08537491 ! astrocyte development GO:0014002 15 6 0,000 0,03165188 0,0852793 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03165188 0,08518391 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03165188 0,08508873 ! interaction with symbiont GO:0051702 13 6 0,000 0,03165188 0,08499377 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03165188 0,08489901 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03165188 0,08480447 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03165188 0,08471014 ! response to copper ion GO:0046688 10 6 0,000 0,03165188 0,08461602 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03165188 0,0845221 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03165188 0,0844284 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03165188 0,0843349 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03165188 0,08424161 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03165188 0,08414853 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03165188 0,08405565 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03165188 0,08396297 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03165188 0,0838705 ! Schwann cell development GO:0014044 15 6 0,000 0,03165188 0,08377824 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03165188 0,08368617 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03165188 0,08359431 ! subpallium development GO:0021544 10 6 0,000 0,03165188 0,08350265 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03165188 0,08341119 ! histone ubiquitination GO:0016574 8 6 0,000 0,03165188 0,08331993 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03165188 0,08322887 ! G2 phase GO:0051319 16 6 0,000 0,03165188 0,08313801 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03165188 0,08304735 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03165188 0,08295688 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03165188 0,08286661 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03165188 0,08277654 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03165188 0,08268666 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03165188 0,08259698 ! receptor internalization GO:0031623 10 6 0,000 0,03165188 0,08250749 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03165188 0,0824182 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03165188 0,0823291 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03165188 0,08224019 ! protein deubiquitination GO:0016579 14 6 0,000 0,03165188 0,08215147 ! protein destabilization GO:0031648 9 6 0,000 0,03165188 0,08206295 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03165188 0,08197461 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03165188 0,08188647 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03165188 0,08179851 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03165188 0,08171075 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03165188 0,08162317 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03165188 0,08153578 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03165188 0,08144857 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03165188 0,08136156 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03165188 0,08127472 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03165188 0,08118808 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03165188 0,08110161 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03165188 0,08101534 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03165188 0,08092924 ! catecholamine transport GO:0051937 9 6 0,000 0,03165188 0,08084333 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03165188 0,0807576 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03165188 0,08067205 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03165188 0,08058668 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03165188 0,0805015 ! maternal placenta development GO:0001893 12 6 0,000 0,03165188 0,08041649 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03165188 0,08033166 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03165188 0,08024701 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03165188 0,08016254 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03165188 0,08007825 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03165188 0,07999413 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03165188 0,0799102 ! heterocycle catabolic process GO:0046700 85 54 1,000 0,03390051 0,08549752 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,03505869 0,08832588 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,03505869 0,08823349 ! heart morphogenesis GO:0003007 97 55 1,000 0,03505869 0,08814129 ! nuclear export GO:0051168 97 55 1,000 0,03505869 0,08804928 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,03623208 0,09090134 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,03623208 0,09080665 ! tRNA transcription GO:0009304 14 7 0,000 0,03682952 0,09220794 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03682952 0,09211209 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03682952 0,09201644 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03682952 0,09192098 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03682952 0,09182573 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03682952 0,09173067 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03682952 0,09163581 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03682952 0,09154114 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03682952 0,09144668 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03682952 0,0913524 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03682952 0,09125832 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03682952 0,09116443 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03682952 0,09107074 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03682952 0,09097724 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03682952 0,09088393 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03682952 0,09079081 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03682952 0,09069788 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03682952 0,09060514 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03682952 0,09051259 ! glycolipid transport GO:0046836 10 7 0,000 0,03682952 0,09042023 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03682952 0,09032806 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03682952 0,09023608 ! neuron adhesion GO:0007158 12 7 0,000 0,03682952 0,09014428 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03682952 0,09005267 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03682952 0,08996125 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03682952 0,08987001 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03682952 0,08977895 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03682952 0,08968809 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03682952 0,0895974 ! pericardium development GO:0060039 14 7 0,000 0,03682952 0,0895069 ! fibril organization GO:0043206 16 7 0,000 0,03682952 0,08941658 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03682952 0,08932644 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03682952 0,08923648 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03682952 0,08914671 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03682952 0,08905711 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03682952 0,0889677 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03682952 0,08887846 ! rhythmic behavior GO:0007622 15 7 0,000 0,03682952 0,08878941 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03682952 0,08870053 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03682952 0,08861183 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03682952 0,0885233 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03682952 0,08843496 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03682952 0,08834679 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03682952 0,08825879 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03682952 0,08817097 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03682952 0,08808333 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03682952 0,08799586 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03682952 0,08790856 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03682952 0,08782144 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03682952 0,08773448 ! spinal cord patterning GO:0021511 13 7 0,000 0,03682952 0,0876477 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03682952 0,0875611 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03682952 0,08747466 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03682952 0,08738839 ! adrenal gland development GO:0030325 17 7 0,000 0,03682952 0,08730229 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03682952 0,08721637 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03682952 0,08713061 ! ovulation GO:0030728 9 7 0,000 0,03682952 0,08704502 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03682952 0,0869596 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03682952 0,08687434 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03682952 0,08678925 ! microtubule nucleation GO:0007020 20 7 0,000 0,03682952 0,08670433 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03682952 0,08661958 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03682952 0,08653499 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03682952 0,08645056 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03682952 0,0863663 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03682952 0,08628221 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03682952 0,08619828 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03682952 0,08611451 ! galactose metabolic process GO:0006012 13 7 0,000 0,03682952 0,0860309 ! vesicle fusion GO:0006906 17 7 0,000 0,03682952 0,08594746 ! response to dietary excess GO:0002021 8 7 0,000 0,03682952 0,08586417 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03682952 0,08578105 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03682952 0,08569809 GO:0045851|pH reduction, ! melanosome organization GO:0032438 9 7 0,000 0,03682952 0,08561529 ! purine salvage GO:0043101 10 7 0,000 0,03682952 0,08553265 ! nucleoside transport GO:0015858 8 7 0,000 0,03682952 0,08545017 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03682952 0,08536785 ! parturition GO:0007567 14 7 0,000 0,03682952 0,08528569 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03682952 0,08520368 ! rRNA modification GO:0000154 14 7 0,000 0,03682952 0,08512183 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03682952 0,08504014 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03682952 0,08495861 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03682952 0,08487723 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03682952 0,08479601 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03682952 0,08471494 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03682952 0,08463403 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03682952 0,08455327 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03682952 0,08447267 ! fibrinolysis GO:0042730 10 7 0,000 0,03682952 0,08439222 ! eating behavior GO:0042755 7 7 0,000 0,03682952 0,08431192 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03682952 0,08423178 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03682952 0,08415178 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03682952 0,08407194 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03682952 0,08399225 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03682952 0,08391272 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03682952 0,08383333 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03682952 0,08375409 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03682952 0,083675 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03682952 0,08359606 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03682952 0,08351727 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03682952 0,08343863 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03682952 0,08336014 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03682952 0,08328179 ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03682952 0,08320359 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03682952 0,08312554 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03682952 0,08304764 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03682952 0,08296988 ! transcription termination GO:0006353 13 7 0,000 0,03682952 0,08289226 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03682952 0,08281479 ! anaphase GO:0051322 17 7 0,000 0,03682952 0,08273747 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03682952 0,08266029 ! axonal fasciculation GO:0007413 18 7 0,000 0,03682952 0,08258325 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03682952 0,08250636 ! diuresis GO:0030146 12 7 0,000 0,03682952 0,08242961 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03682952 0,082353 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03682952 0,08227653 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03682952 0,08220021 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03682952 0,08212403 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03682952 0,08204799 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03682952 0,08197209 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03682952 0,08189633 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03682952 0,08182071 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03682952 0,08174523 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03682952 0,08166989 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03682952 0,08159469 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03682952 0,08151962 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,03682952 0,08144469 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03682952 0,08136991 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03682952 0,08129526 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03682952 0,08122074 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03682952 0,08114636 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03682952 0,08107212 ! adult feeding behavior GO:0008343 9 7 0,000 0,03682952 0,08099801 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03682952 0,08092404 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03682952 0,08085021 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03682952 0,08077651 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03682952 0,08070294 ! retina homeostasis GO:0001895 12 7 0,000 0,03682952 0,08062951 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03682952 0,08055621 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03682952 0,08048304 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03682952 0,08041001 ! protein prenylation GO:0018342 18 7 0,000 0,03682952 0,08033711 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03682952 0,08026434 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03682952 0,0801917 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03682952 0,08011919 ! lipid modification GO:0030258 97 57 1,000 0,03742048 0,08133124 ! maintenance of location GO:0051235 118 57 1,000 0,03742048 0,08125783 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,03984157 0,08643716 ! DNA catabolic process GO:0006308 86 59 1,000 0,03984157 0,08635929 ! camera-type eye development GO:0043010 116 60 1,000 0,04107387 0,08895025 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04197965 0,09083008 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04197965 0,09074847 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04197965 0,090667 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04197965 0,09058569 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04197965 0,09050452 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04197965 0,09042349 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04197965 0,09034261 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04197965 0,09026188 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04197965 0,09018129 ! meiotic prophase I GO:0007128 13 8 0,000 0,04197965 0,09010084 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04197965 0,09002054 ! oligopeptide transport GO:0006857 15 8 0,000 0,04197965 0,08994038 ! UTP metabolic process GO:0046051 8 8 0,000 0,04197965 0,08986036 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04197965 0,08978048 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04197965 0,08970075 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04197965 0,08962116 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04197965 0,08954171 ! succinate metabolic process GO:0006105 14 8 0,000 0,04197965 0,08946239 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04197965 0,08938322 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04197965 0,08930419 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04197965 0,0892253 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04197965 0,08914655 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04197965 0,08906794 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04197965 0,08898947 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04197965 0,08891113 ! reflex GO:0060004 16 8 0,000 0,04197965 0,08883293 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04197965 0,08875487 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04197965 0,08867695 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04197965 0,08859916 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04197965 0,08852151 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04197965 0,088444 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04197965 0,08836662 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04197965 0,08828937 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04197965 0,08821227 ! histidine metabolic process GO:0006547 16 8 0,000 0,04197965 0,08813529 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04197965 0,08805845 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04197965 0,08798175 ! glycine catabolic process GO:0006546 13 8 0,000 0,04197965 0,08790517 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04197965 0,08782873 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04197965 0,08775243 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04197965 0,08767625 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04197965 0,08760021 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04197965 0,0875243 ! macrophage activation GO:0042116 12 8 0,000 0,04197965 0,08744852 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04197965 0,08737288 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04197965 0,08729736 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04197965 0,08722197 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04197965 0,08714672 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04197965 0,08707159 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04197965 0,08699659 ! osteoblast development GO:0002076 16 8 0,000 0,04197965 0,08692172 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04197965 0,08684698 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04197965 0,08677237 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04197965 0,08669789 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04197965 0,08662354 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04197965 0,08654931 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04197965 0,08647521 ! intermediate filament organization GO:0045109 12 8 0,000 0,04197965 0,08640123 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04197965 0,08632739 ! cellular extravasation GO:0045123 12 8 0,000 0,04197965 0,08625367 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04197965 0,08618007 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04197965 0,0861066 ! response to antibiotic GO:0046677 11 8 0,000 0,04197965 0,08603326 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04197965 0,08596004 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04197965 0,08588694 ! DNA topological change GO:0006265 12 8 0,000 0,04197965 0,08581397 ! response to tropane GO:0014073 15 8 0,000 0,04197965 0,08574112 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04197965 0,0856684 ! melanosome transport GO:0032402 13 8 0,000 0,04197965 0,0855958 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04197965 0,08552332 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04197965 0,08545097 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04197965 0,08537874 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04197965 0,08530662 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04197965 0,08523464 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04197965 0,08516277 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04197965 0,08509102 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04197965 0,0850194 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04197965 0,08494789 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04197965 0,08487651 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04197965 0,08480524 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04197965 0,0847341 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04197965 0,08466307 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04197965 0,08459216 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04197965 0,08452138 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04197965 0,08445071 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04197965 0,08438015 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04197965 0,08430972 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04197965 0,0842394 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04197965 0,0841692 ! hormone catabolic process GO:0042447 17 8 0,000 0,04197965 0,08409912 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04197965 0,08402915 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04197965 0,0839593 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04197965 0,08388957 ! ATP catabolic process GO:0006200 11 8 0,000 0,04197965 0,08381995 ! blastocyst growth GO:0001832 19 8 0,000 0,04197965 0,08375045 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04197965 0,08368106 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04197965 0,08361179 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04197965 0,08354263 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04197965 0,08347359 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04197965 0,08340466 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04197965 0,08333584 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04197965 0,08326714 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04197965 0,08319855 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04197965 0,08313008 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04197965 0,08306171 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04197965 0,08299346 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04197965 0,08292532 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04197965 0,0828573 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04197965 0,08278938 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04197965 0,08272158 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04197965 0,08265388 ! ear development GO:0043583 103 62 1,000 0,04358106 0,08573674 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,04614381 0,09070425 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,04614381 0,0906302 GO:0048609|reproductive process in a multicellular organism, ! axon extension GO:0048675 15 9 0,000 0,04710242 0,09243753 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04710242 0,09236219 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04710242 0,09228698 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04710242 0,09221189 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04710242 0,09213692 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04710242 0,09206207 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04710242 0,09198735 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04710242 0,09191274 ! phosphate transport GO:0006817 19 9 0,000 0,04710242 0,09183826 ! reproductive behavior GO:0019098 19 9 0,000 0,04710242 0,0917639 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04710242 0,09168965 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04710242 0,09161553 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04710242 0,09154153 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04710242 0,09146764 ! GTP metabolic process GO:0046039 9 9 0,000 0,04710242 0,09139388 ! RNA methylation GO:0001510 15 9 0,000 0,04710242 0,09132024 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04710242 0,09124671 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04710242 0,0911733 ! artery development GO:0060840 24 9 0,000 0,04710242 0,09110001 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04710242 0,09102684 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04710242 0,09095378 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04710242 0,09088084 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04710242 0,09080802 ! chemosensory behavior GO:0007635 20 9 0,000 0,04710242 0,09073532 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04710242 0,09066273 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04710242 0,09059026 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04710242 0,0905179 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04710242 0,09044566 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04710242 0,09037353 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04710242 0,09030152 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04710242 0,09022963 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04710242 0,09015785 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04710242 0,09008618 ! protein targeting to ER GO:0045047 22 9 0,000 0,04710242 0,09001462 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04710242 0,08994318 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04710242 0,08987186 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04710242 0,08980064 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04710242 0,08972954 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04710242 0,08965855 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04710242 0,08958768 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04710242 0,08951691 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04710242 0,08944626 ! mannose metabolic process GO:0006013 13 9 0,000 0,04710242 0,08937572 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04710242 0,08930529 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04710242 0,08923497 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04710242 0,08916476 ! receptor clustering GO:0043113 18 9 0,000 0,04710242 0,08909466 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04710242 0,08902468 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04710242 0,0889548 ! ruffle organization GO:0031529 15 9 0,000 0,04710242 0,08888503 ! retinol metabolic process GO:0042572 18 9 0,000 0,04710242 0,08881537 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04710242 0,08874582 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04710242 0,08867638 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04710242 0,08860705 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04710242 0,08853782 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,04710242 0,08846871 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04710242 0,0883997 ! segment specification GO:0007379 13 9 0,000 0,04710242 0,0883308 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04710242 0,088262 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04710242 0,08819332 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04710242 0,08812474 ! response to amine stimulus GO:0014075 13 9 0,000 0,04710242 0,08805626 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04710242 0,0879879 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04710242 0,08791964 ! erythrocyte development GO:0048821 15 9 0,000 0,04710242 0,08785148 ! gas homeostasis GO:0033483 16 9 0,000 0,04710242 0,08778343 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04710242 0,08771549 ! renal water homeostasis GO:0003091 14 9 0,000 0,04710242 0,08764765 ! postreplication repair GO:0006301 22 9 0,000 0,04710242 0,08757992 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04710242 0,08751229 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04710242 0,08744476 ! icosanoid secretion GO:0032309 15 9 0,000 0,04710242 0,08737734 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04710242 0,08731002 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04710242 0,08724281 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 15 9 0,000 0,04710242 0,0871757 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04710242 0,08710869 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04710242 0,08704179 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04710242 0,08697499 ! sterol catabolic process GO:0016127 11 9 0,000 0,04710242 0,08690829 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04710242 0,08684169 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04710242 0,0867752 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04710242 0,08670881 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04710242 0,08664252 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04710242 0,08657633 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04710242 0,08651024 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04710242 0,08644425 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04710242 0,08637836 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04710242 0,08631258 ! purine base metabolic process GO:0006144 21 9 0,000 0,04710242 0,08624689 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04710242 0,0861813 ! pigment granule transport GO:0051904 17 9 0,000 0,04710242 0,08611581 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04710242 0,08605043 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04710242 0,08598514 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04710242 0,08591995 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04710242 0,08585486 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04710242 0,08578987 ! mitochondrion localization GO:0051646 15 9 0,000 0,04710242 0,08572497 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,04744556 0,08628421 ! secondary metabolic process GO:0019748 116 66 1,000 0,04876065 0,08860885 ! activation of MAPK activity GO:0000187 115 67 1,000 0,05008891 0,0909539 ! chromosome segregation GO:0007059 113 67 1,000 0,05008891 0,09088531 ! adaptive immune response GO:0002250 119 67 1,000 0,05008891 0,09081682 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05219796 0,09456949 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05219796 0,09449833 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05219796 0,09442728 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05219796 0,09435633 ! synapsis GO:0007129 13 10 0,000 0,05219796 0,0942855 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05219796 0,09421476 ! N-glycan processing GO:0006491 20 10 0,000 0,05219796 0,09414414 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05219796 0,09407362 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05219796 0,0940032 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05219796 0,09393289 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05219796 0,09386269 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05219796 0,09379259 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05219796 0,0937226 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05219796 0,09365271 ! androgen metabolic process GO:0008209 17 10 0,000 0,05219796 0,09358292 ! phospholipid efflux GO:0033700 16 10 0,000 0,05219796 0,09351324 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05219796 0,09344366 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05219796 0,09337419 ! pathogenesis GO:0009405 13 10 0,000 0,05219796 0,09330481 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05219796 0,09323555 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05219796 0,09316638 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05219796 0,09309732 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05219796 0,09302836 ! endoderm development GO:0007492 16 10 0,000 0,05219796 0,0929595 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05219796 0,09289074 ! arginine catabolic process GO:0006527 13 10 0,000 0,05219796 0,09282208 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05219796 0,09275353 ! proline metabolic process GO:0006560 13 10 0,000 0,05219796 0,09268508 ! L-serine metabolic process GO:0006563 18 10 0,000 0,05219796 0,09261673 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05219796 0,09254847 ! V(D)J recombination GO:0033151 28 10 0,000 0,05219796 0,09248032 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05219796 0,09241227 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05219796 0,09234432 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05219796 0,09227647 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05219796 0,09220872 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05219796 0,09214107 ! multicellular organism growth GO:0035264 18 10 0,000 0,05219796 0,09207352 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05219796 0,09200607 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05219796 0,09193871 ! epithelial cell development GO:0002064 20 10 0,000 0,05219796 0,09187146 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05219796 0,0918043 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05219796 0,09173724 ! macroautophagy GO:0016236 17 10 0,000 0,05219796 0,09167028 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05219796 0,09160341 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05219796 0,09153665 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05219796 0,09146998 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05219796 0,09140341 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05219796 0,09133693 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05219796 0,09127055 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05219796 0,09120427 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05219796 0,09113808 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05219796 0,09107199 ! response to dsRNA GO:0043331 20 10 0,000 0,05219796 0,091006 ! DNA ligation GO:0006266 19 10 0,000 0,05219796 0,0909401 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05219796 0,0908743 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05219796 0,09080859 ! melanosome localization GO:0032400 16 10 0,000 0,05219796 0,09074298 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05219796 0,09067746 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05219796 0,09061203 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05219796 0,09054671 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05219796 0,09048147 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05219796 0,09041633 ! mRNA cleavage GO:0006379 17 10 0,000 0,05219796 0,09035128 ! protein sumoylation GO:0016925 15 10 0,000 0,05219796 0,09028633 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05219796 0,09022147 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05219796 0,0901567 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05219796 0,09009202 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05219796 0,09002744 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05219796 0,08996295 ! salivary gland development GO:0007431 27 10 0,000 0,05219796 0,08989855 ! prophase GO:0051324 15 10 0,000 0,05219796 0,08983425 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05219796 0,08977004 ! apical protein localization GO:0045176 15 10 0,000 0,05219796 0,08970591 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05219796 0,08964188 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05219796 0,08957795 ! midbrain development GO:0030901 13 10 0,000 0,05219796 0,0895141 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05219796 0,08945034 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05219796 0,08938668 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05219796 0,0893231 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05219796 0,08925962 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05219796 0,08919622 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05219796 0,08913292 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05219796 0,0890697 ! detection of calcium ion GO:0005513 23 10 0,000 0,05219796 0,08900658 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05219796 0,08894354 ! blastocyst formation GO:0001825 17 10 0,000 0,05219796 0,08888059 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05219796 0,08881774 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05219796 0,08875497 ! activation of innate immune response GO:0002218 12 10 0,000 0,05219796 0,08869229 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05219796 0,0886297 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05219796 0,08856719 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05219796 0,08850478 ! localization within membrane GO:0051668 20 10 0,000 0,05219796 0,08844245 ! antigen processing and presentation GO:0019882 104 69 1,000 0,05278423 0,08937287 ! humoral immune response GO:0006959 109 71 1,000 0,05553012 0,09395602 ! regulation of immune effector process GO:0002697 137 71 1,000 0,05553012 0,09389 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0569216 0,09617512 ! carbohydrate transport GO:0008643 110 72 1,000 0,0569216 0,09610762 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05726642 0,09662202 ! respiratory burst GO:0045730 17 11 0,000 0,05726642 0,09655431 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05726642 0,09648669 ! neuron fate specification GO:0048665 17 11 0,000 0,05726642 0,09641917 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05726642 0,09635175 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05726642 0,09628441 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,05726642 0,09621718 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05726642 0,09615003 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05726642 0,09608298 ! response to pain GO:0048265 24 11 0,000 0,05726642 0,09601602 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05726642 0,09594916 ! T cell proliferation GO:0042098 26 11 0,000 0,05726642 0,09588239 ! bone resorption GO:0045453 16 11 0,000 0,05726642 0,09581571 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05726642 0,09574913 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05726642 0,09568264 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05726642 0,09561624 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05726642 0,09554993 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05726642 0,09548371 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05726642 0,09541759 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05726642 0,09535155 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05726642 0,09528561 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05726642 0,09521976 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,05726642 0,095154 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05726642 0,09508833 ! UV protection GO:0009650 19 11 0,000 0,05726642 0,09502276 ! adult heart development GO:0007512 14 11 0,000 0,05726642 0,09495727 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05726642 0,09489187 ! temperature homeostasis GO:0001659 17 11 0,000 0,05726642 0,09482656 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05726642 0,09476134 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05726642 0,09469622 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05726642 0,09463118 ! regulation of organ growth GO:0046620 13 11 0,000 0,05726642 0,09456623 ! pigment granule localization GO:0051875 20 11 0,000 0,05726642 0,09450137 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05726642 0,0944366 ! vasoconstriction GO:0042310 18 11 0,000 0,05726642 0,09437191 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05726642 0,09430732 ! embryonic axis specification GO:0000578 18 11 0,000 0,05726642 0,09424281 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05726642 0,0941784 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05726642 0,09411407 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05726642 0,09404983 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05726642 0,09398567 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05726642 0,09392161 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05726642 0,09385763 ! zymogen activation GO:0031638 15 11 0,000 0,05726642 0,09379373 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05726642 0,09372993 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05726642 0,09366621 ! nucleosome positioning GO:0016584 15 11 0,000 0,05726642 0,09360258 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05726642 0,09353903 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05726642 0,09347557 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05726642 0,0934122 ! acid secretion GO:0046717 18 11 0,000 0,05726642 0,09334891 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05726642 0,09328571 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05726642 0,0932226 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05726642 0,09315956 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05726642 0,09309662 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,05726642 0,09303376 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05726642 0,09297098 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05726642 0,09290829 ! germ cell migration GO:0008354 25 11 0,000 0,05726642 0,09284568 ! embryonic gut development GO:0048566 15 11 0,000 0,05726642 0,09278316 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05726642 0,09272072 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05726642 0,09265837 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05726642 0,0925961 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05726642 0,09253391 ! defense response to fungus GO:0050832 13 11 0,000 0,05726642 0,09247181 ! developmental induction GO:0031128 19 11 0,000 0,05726642 0,09240979 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05726642 0,09234785 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05726642 0,092286 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05726642 0,09222423 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05726642 0,09216254 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05726642 0,09210093 ! regulation of blood pressure GO:0008217 125 73 1,000 0,05832521 0,09374112 ! meiosis GO:0007126 121 74 1,000 0,05974078 0,09595215 GO:0051327|M phase of meiotic cell cycle, ! eye development GO:0001654 143 74 1,000 0,05974078 0,09588814 ! meiotic cell cycle GO:0051321 122 75 1,000 0,06116815 0,09811372 ! rhythmic process GO:0048511 128 75 1,000 0,06116815 0,09804835 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06230794 0,09980886 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06230794 0,09974245 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06230794 0,09967613 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06230794 0,0996099 ! cartilage condensation GO:0001502 20 12 0,000 0,06230794 0,09954376 ! mating GO:0007618 17 12 0,000 0,06230794 0,0994777 ! protein complex disassembly GO:0043241 27 12 0,000 0,06230794 0,09941174 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06230794 0,09934586 ! hippocampus development GO:0021766 26 12 0,000 0,06230794 0,09928007 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,06230794 0,09921436 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06230794 0,09914874 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06230794 0,09908321 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06230794 0,09901777 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06230794 0,09895241 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06230794 0,09888714 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06230794 0,09882195 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06230794 0,09875685 ! drug transport GO:0015893 16 12 0,000 0,06230794 0,09869184 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06230794 0,09862691 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06230794 0,09856207 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06230794 0,09849731 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06230794 0,09843263 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06230794 0,09836805 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06230794 0,09830354 ! forebrain cell migration GO:0021885 21 12 0,000 0,06230794 0,09823912 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06230794 0,09817479 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06230794 0,09811054 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06230794 0,09804637 ! monoamine transport GO:0015844 18 12 0,000 0,06230794 0,09798229 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06230794 0,09791829 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06230794 0,09785437 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06230794 0,09779054 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06230794 0,09772679 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06230794 0,09766313 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06230794 0,09759954 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06230794 0,09753604 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06230794 0,09747263 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06230794 0,09740929 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06230794 0,09734604 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06230794 0,09728287 ! cranial nerve development GO:0021545 20 12 0,000 0,06230794 0,09721978 ! fucose catabolic process GO:0019317 22 12 0,000 0,06230794 0,09715677 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06230794 0,09709385 ! histone methylation GO:0016571 26 12 0,000 0,06230794 0,097031 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06230794 0,09696824 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06230794 0,09690556 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06230794 0,09684296 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06230794 0,09678044 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06230794 0,096718 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06230794 0,09665564 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06230794 0,09659336 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06230794 0,09653117 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06230794 0,09646905 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06230794 0,09640701 ! response to cold GO:0009409 17 12 0,000 0,06230794 0,09634505 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06230794 0,09628317 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06230794 0,09622137 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,06405763 0,09885994 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,06699233 0,10332279 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06732267 0,10376575 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06732267 0,10369932 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06732267 0,10363297 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06732267 0,10356671 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06732267 0,10350054 ! lipid localization GO:0010876 28 13 0,000 0,06732267 0,10343444 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06732267 0,10336844 ! organelle fusion GO:0048284 32 13 0,000 0,06732267 0,10330251 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06732267 0,10323667 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06732267 0,10317092 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06732267 0,10310524 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06732267 0,10303966 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06732267 0,10297415 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06732267 0,10290873 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06732267 0,10284339 ! methionine metabolic process GO:0006555 27 13 0,000 0,06732267 0,10277813 ! plasma membrane organization GO:0007009 24 13 0,000 0,06732267 0,10271296 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06732267 0,10264787 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06732267 0,10258286 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06732267 0,10251794 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06732267 0,10245309 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06732267 0,10238833 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06732267 0,10232365 ! exocrine system development GO:0035272 32 13 0,000 0,06732267 0,10225905 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06732267 0,10219454 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06732267 0,1021301 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06732267 0,10206575 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06732267 0,10200147 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06732267 0,10193728 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06732267 0,10187317 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06732267 0,10180914 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06732267 0,10174519 ! ribosome assembly GO:0042255 17 13 0,000 0,06732267 0,10168132 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06732267 0,10161753 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06732267 0,10155382 ! chromatin silencing GO:0006342 26 13 0,000 0,06732267 0,10149019 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06732267 0,10142664 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06732267 0,10136317 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06732267 0,10129977 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06732267 0,10123646 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06732267 0,10117323 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06732267 0,10111007 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06732267 0,101047 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06732267 0,100984 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06732267 0,10092108 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06732267 0,10085824 ! embryonic placenta development GO:0001892 23 13 0,000 0,06732267 0,10079548 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06732267 0,1007328 ! insulin secretion GO:0030073 23 13 0,000 0,06732267 0,10067019 ! actin filament polymerization GO:0030041 24 13 0,000 0,06732267 0,10060766 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06732267 0,10054521 ! acrosome reaction GO:0007340 18 13 0,000 0,06732267 0,10048284 ! muscle cell differentiation GO:0042692 159 80 1,000 0,06847624 0,10214125 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,06847624 0,10207797 ! rRNA transcription GO:0009303 25 14 0,000 0,07231074 0,10772734 ! lactation GO:0007595 26 14 0,000 0,07231074 0,10766068 ! reproductive cellular process GO:0048610 20 14 0,000 0,07231074 0,10759409 ! tRNA modification GO:0006400 20 14 0,000 0,07231074 0,1075276 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07231074 0,10746118 ! regulation of S phase GO:0033261 23 14 0,000 0,07231074 0,10739485 ! water transport GO:0006833 21 14 0,000 0,07231074 0,10732859 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07231074 0,10726242 ! non-recombinational repair GO:0000726 25 14 0,000 0,07231074 0,10719633 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07231074 0,10713033 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07231074 0,1070644 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07231074 0,10699856 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07231074 0,10693279 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07231074 0,10686711 ! palate development GO:0060021 31 14 0,000 0,07231074 0,1068015 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07231074 0,10673598 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07231074 0,10667054 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07231074 0,10660518 ! arginine metabolic process GO:0006525 17 14 0,000 0,07231074 0,1065399 ! regulation of heart rate GO:0002027 24 14 0,000 0,07231074 0,10647469 ! organic alcohol transport GO:0015850 29 14 0,000 0,07231074 0,10640957 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07231074 0,10634453 ! embryo implantation GO:0007566 30 14 0,000 0,07231074 0,10627957 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07231074 0,10621468 ! L-amino acid transport GO:0015807 30 14 0,000 0,07231074 0,10614988 ! bone mineralization GO:0030282 17 14 0,000 0,07231074 0,10608515 ! stem cell development GO:0048864 43 14 0,000 0,07231074 0,10602051 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07231074 0,10595594 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07231074 0,10589145 ! cerebellum development GO:0021549 21 14 0,000 0,07231074 0,10582704 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07231074 0,10576271 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07231074 0,10569845 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07231074 0,10563428 ! cofactor transport GO:0051181 26 14 0,000 0,07231074 0,10557018 ! NADP metabolic process GO:0006739 24 14 0,000 0,07231074 0,10550616 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07231074 0,10544221 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07231074 0,10537835 ! intestinal absorption GO:0050892 25 14 0,000 0,07231074 0,10531456 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07231074 0,10525085 ! oxygen transport GO:0015671 21 14 0,000 0,07231074 0,10518721 ! male genitalia development GO:0030539 24 14 0,000 0,07231074 0,10512366 ! regulation of axon extension GO:0030516 37 14 0,000 0,07231074 0,10506018 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07231074 0,10499677 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,07451862 0,1081374 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,07605513 0,11030057 GO:0002696|positive regulation of leukocyte activation, ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07727231 0,1119983 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,07727231 0,11193087 ! superoxide anion generation GO:0042554 20 15 0,000 0,07727231 0,11186352 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07727231 0,11179626 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07727231 0,11172907 ! copper ion transport GO:0006825 20 15 0,000 0,07727231 0,11166197 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,07727231 0,11159494 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07727231 0,111528 ! sulfate transport GO:0008272 23 15 0,000 0,07727231 0,11146114 ! response to cAMP GO:0051591 22 15 0,000 0,07727231 0,11139435 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07727231 0,11132765 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07727231 0,11126103 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07727231 0,11119448 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07727231 0,11112802 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07727231 0,11106163 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07727231 0,11099533 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07727231 0,1109291 ! pituitary gland development GO:0021983 29 15 0,000 0,07727231 0,11086295 ! vesicle coating GO:0006901 33 15 0,000 0,07727231 0,11079689 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07727231 0,1107309 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07727231 0,11066499 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07727231 0,11059915 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07727231 0,1105334 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,07727231 0,11046772 ! histone deacetylation GO:0016575 20 15 0,000 0,07727231 0,11040212 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07727231 0,1103366 ! tissue regeneration GO:0042246 26 15 0,000 0,07727231 0,11027116 ! water homeostasis GO:0030104 27 15 0,000 0,07727231 0,11020579 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07727231 0,11014051 ! muscle maintenance GO:0046716 26 15 0,000 0,07727231 0,1100753 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07727231 0,11001016 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07727231 0,10994511 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07727231 0,10988013 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07727231 0,10981522 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07727231 0,1097504 ! cell killing GO:0001906 29 15 0,000 0,07727231 0,10968565 ! detection of bacterium GO:0016045 18 15 0,000 0,07727231 0,10962098 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,07727231 0,10955638 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07727231 0,10949186 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07727231 0,10942741 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07727231 0,10936304 ! peptide hormone processing GO:0016486 23 15 0,000 0,07727231 0,10929875 ! tube morphogenesis GO:0035239 176 86 1,000 0,0776017 0,10970017 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,07915817 0,11183474 ! regulation of neurological system process GO:0031644 148 88 1,000 0,08072441 0,1139806 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,0822075 0,1160066 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0822075 0,1159386 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0822075 0,11587068 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,0822075 0,11580284 ! bone remodeling GO:0046849 27 16 0,000 0,0822075 0,11573508 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,0822075 0,1156674 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0822075 0,11559979 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0822075 0,11553227 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0822075 0,11546483 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0822075 0,11539746 ! startle response GO:0001964 28 16 0,000 0,0822075 0,11533017 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0822075 0,11526296 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0822075 0,11519583 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0822075 0,11512878 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,0822075 0,11506181 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0822075 0,11499491 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0822075 0,11492809 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0822075 0,11486135 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0822075 0,11479469 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0822075 0,1147281 ! response to osmotic stress GO:0006970 25 16 0,000 0,0822075 0,11466159 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,0822075 0,11459516 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,0822075 0,11452881 ! fructose metabolic process GO:0006000 25 16 0,000 0,0822075 0,11446253 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0822075 0,11439633 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0822075 0,1143302 ! intermediate filament-based process GO:0045103 32 16 0,000 0,0822075 0,11426415 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0822075 0,11419818 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0822075 0,11413228 ! axon cargo transport GO:0008088 43 16 0,000 0,0822075 0,11406646 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0822075 0,11400072 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0822075 0,11393505 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,0822075 0,11386946 ! DNA replication initiation GO:0006270 27 16 0,000 0,0822075 0,11380394 ! neuron recognition GO:0008038 35 16 0,000 0,0822075 0,1137385 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0822075 0,11367313 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0822075 0,11360784 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0822075 0,11354262 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0822075 0,11347748 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0822075 0,11341241 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0822075 0,11334742 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0822075 0,1132825 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0822075 0,11321766 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0822075 0,11315289 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0822075 0,11308819 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,08230027 0,11315111 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,08711646 0,11970429 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,08711646 0,11963596 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,08711646 0,11956771 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,08711646 0,11949955 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,08711646 0,11943146 ! signal complex assembly GO:0007172 41 17 0,000 0,08711646 0,11936344 ! endothelial cell migration GO:0043542 28 17 0,000 0,08711646 0,11929551 ! inositol metabolic process GO:0006020 28 17 0,000 0,08711646 0,11922765 ! gene silencing by RNA GO:0031047 36 17 0,000 0,08711646 0,11915987 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,08711646 0,11909216 ! glial cell development GO:0021782 27 17 0,000 0,08711646 0,11902453 ! limbic system development GO:0021761 36 17 0,000 0,08711646 0,11895698 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,08711646 0,11888951 ! adult walking behavior GO:0007628 33 17 0,000 0,08711646 0,11882211 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,08711646 0,11875479 ! heart looping GO:0001947 30 17 0,000 0,08711646 0,11868754 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,08711646 0,11862038 ! myoblast differentiation GO:0045445 45 17 0,000 0,08711646 0,11855328 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,08711646 0,11848627 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,08711646 0,11841932 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,08711646 0,11835246 ! glycine metabolic process GO:0006544 28 17 0,000 0,08711646 0,11828567 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,08711646 0,11821895 ! NAD metabolic process GO:0019674 29 17 0,000 0,08711646 0,11815231 ! membrane budding GO:0006900 37 17 0,000 0,08711646 0,11808575 ! DNA integration GO:0015074 29 17 0,000 0,08711646 0,11801926 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,08711646 0,11795284 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,08711646 0,1178865 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,08711646 0,11782024 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,08711646 0,11775405 ! genitalia development GO:0048806 30 17 0,000 0,08711646 0,11768793 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,08711646 0,11762189 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,08711646 0,11755592 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,08711646 0,11749002 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,08711646 0,1174242 ! steroid catabolic process GO:0006706 31 17 0,000 0,08711646 0,11735846 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,08711646 0,11729278 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,08711646 0,11722718 ! gas transport GO:0015669 25 17 0,000 0,08711646 0,11716166 ! organic cation transport GO:0015695 31 17 0,000 0,08711646 0,1170962 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,08711646 0,11703082 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,08711646 0,11696552 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,08711646 0,11690028 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,08711646 0,11683512 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,08869692 0,11888846 ! regulation of membrane potential GO:0042391 164 93 1,000 0,08869692 0,11882227 ! female pregnancy GO:0007565 164 94 1,000 0,09031868 0,12092751 ! regulation of T cell activation GO:0050863 158 94 1,000 0,09031868 0,12086026 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09199933 0,12304079 ! neuron maturation GO:0042551 42 18 0,000 0,09199933 0,12297243 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09199933 0,12290415 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09199933 0,12283595 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09199933 0,12276782 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09199933 0,12269977 ! memory GO:0007613 31 18 0,000 0,09199933 0,12263179 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09199933 0,12256389 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09199933 0,12249606 ! patterning of blood vessels GO:0001569 39 18 0,000 0,09199933 0,12242831 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09199933 0,12236063 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09199933 0,12229303 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09199933 0,1222255 ! response to fungus GO:0009620 21 18 0,000 0,09199933 0,12215805 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09199933 0,12209067 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09199933 0,12202336 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09199933 0,12195613 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09199933 0,12188897 ! vitamin transport GO:0051180 27 18 0,000 0,09199933 0,12182189 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09199933 0,12175488 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09199933 0,12168795 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09199933 0,12162109 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09199933 0,1215543 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09199933 0,12148758 ! nerve development GO:0021675 28 18 0,000 0,09199933 0,12142094 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09199933 0,12135437 ! protein ubiquitination GO:0016567 217 97 1,000 0,09523595 0,1255549 ! regulation of protein localization GO:0032880 176 97 1,000 0,09523595 0,12548614 ! protein secretion GO:0009306 39 19 0,000 0,09685624 0,12755123 ! positive regulation of translation GO:0045727 30 19 0,000 0,09685624 0,12748146 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09685624 0,12741176 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09685624 0,12734213 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09685624 0,12727258 ! skin development GO:0043588 36 19 0,000 0,09685624 0,12720311 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09685624 0,12713372 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09685624 0,1270644 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09685624 0,12699515 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09685624 0,12692598 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09685624 0,12685689 ! cerebral cortex development GO:0021987 36 19 0,000 0,09685624 0,12678787 ! neuromuscular junction development GO:0007528 34 19 0,000 0,09685624 0,12671892 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09685624 0,12665006 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09685624 0,12658126 ! peptide cross-linking GO:0018149 37 19 0,000 0,09685624 0,12651254 ! heart process GO:0003015 30 19 0,000 0,09685624 0,1264439 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09685624 0,12637533 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,09685624 0,12630683 ! visual learning GO:0008542 36 19 0,000 0,09685624 0,12623841 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,09685624 0,12617006 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09685624 0,12610179 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09685624 0,12603359 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09685624 0,12596546 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09685624 0,12589741 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09685624 0,12582943 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09685624 0,12576152 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09685624 0,12569369 ! cilium assembly GO:0042384 37 19 0,000 0,09685624 0,12562593 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09685624 0,12555824 ! response to virus GO:0009615 160 98 1,000 0,09689191 0,12553686 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,09855608 0,12762429 GO:0060538|skeletal muscle organ development, ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10168733 0,13160823 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,10168733 0,13153748 ! positive regulation of ossification GO:0045778 47 20 0,000 0,10168733 0,13146679 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10168733 0,13139619 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10168733 0,13132566 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,10168733 0,13125521 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10168733 0,13118483 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10168733 0,13111453 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10168733 0,1310443 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10168733 0,13097415 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10168733 0,13090407 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,10168733 0,13083407 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10168733 0,13076414 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10168733 0,13069429 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10168733 0,13062451 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10168733 0,1305548 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10168733 0,13048518 ! body fluid secretion GO:0007589 31 20 0,000 0,10168733 0,13041562 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10168733 0,13034614 ! peptide secretion GO:0002790 35 20 0,000 0,10168733 0,13027673 ! stem cell differentiation GO:0048863 53 20 0,000 0,10168733 0,1302074 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10168733 0,13013814 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10168733 0,13006896 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10168733 0,12999984 ! sensory perception of pain GO:0019233 30 20 0,000 0,10168733 0,1299308 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10168733 0,12986184 ! diencephalon development GO:0021536 34 20 0,000 0,10168733 0,12979295 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10168733 0,12972413 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,10168733 0,12965538 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10168733 0,12958671 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10168733 0,12951811 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10168733 0,12944958 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10168733 0,12938112 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10168733 0,12931274 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,10168733 0,12924443 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10168733 0,12917619 ! actin filament-based movement GO:0030048 43 20 0,000 0,10168733 0,12910802 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10168733 0,12903993 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10168733 0,12897191 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,10168733 0,12890395 ! regulation of cell killing GO:0031341 42 21 0,000 0,10649273 0,13492444 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10649273 0,13485343 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10649273 0,13478249 ! hormone secretion GO:0046879 38 21 0,000 0,10649273 0,13471163 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10649273 0,13464084 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10649273 0,13457012 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10649273 0,13449948 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10649273 0,13442892 ! axis specification GO:0009798 38 21 0,000 0,10649273 0,13435842 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10649273 0,13428801 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10649273 0,13421766 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10649273 0,13414739 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10649273 0,13407719 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,10649273 0,13400707 ! cytolysis GO:0019835 24 21 0,000 0,10649273 0,13393702 ! vasodilation GO:0042311 39 21 0,000 0,10649273 0,13386704 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10649273 0,13379714 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,10649273 0,1337273 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10649273 0,13365755 ! DNA modification GO:0006304 34 21 0,000 0,10649273 0,13358786 ! collagen fibril organization GO:0030199 59 21 0,000 0,10649273 0,13351825 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10649273 0,13344871 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10649273 0,13337924 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,10649273 0,13330984 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10649273 0,13324052 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10649273 0,13317127 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,10649273 0,13310209 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10649273 0,13303298 ! collagen catabolic process GO:0030574 28 21 0,000 0,10649273 0,13296394 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10649273 0,13289498 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,11127259 0,1387879 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11127259 0,13871599 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11127259 0,13864415 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11127259 0,13857239 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,11127259 0,1385007 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11127259 0,13842909 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,11127259 0,13835755 ! keratinization GO:0031424 28 22 0,000 0,11127259 0,13828608 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11127259 0,13821469 ! sensory perception of taste GO:0050909 28 22 0,000 0,11127259 0,13814337 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,11127259 0,13807213 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11127259 0,13800096 ! vacuolar transport GO:0007034 36 22 0,000 0,11127259 0,13792986 ! lysosome organization GO:0007040 41 22 0,000 0,11127259 0,13785884 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11127259 0,13778788 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11127259 0,137717 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11127259 0,1376462 ! fucose metabolic process GO:0006004 39 22 0,000 0,11127259 0,13757547 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11127259 0,13750481 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11127259 0,13743422 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11127259 0,1373637 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,11127259 0,13729326 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11127259 0,13722289 ! sarcomere organization GO:0045214 30 22 0,000 0,11127259 0,13715259 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11127259 0,13708236 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11127259 0,13701221 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11127259 0,13694213 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11127259 0,13687212 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,11602704 0,14264745 ! gluconeogenesis GO:0006094 33 23 0,000 0,11602704 0,1425746 ! viral genome replication GO:0019079 41 23 0,000 0,11602704 0,14250182 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,11602704 0,14242911 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,11602704 0,14235648 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,11602704 0,14228392 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,11602704 0,14221144 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,11602704 0,14213903 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,11602704 0,1420667 ! visual behavior GO:0007632 42 23 0,000 0,11602704 0,14199444 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,11602704 0,14192225 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,11602704 0,14185013 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,11602704 0,14177809 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,11602704 0,14170612 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,11602704 0,14163423 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,11602704 0,1415624 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,11602704 0,14149065 GO:0051693|actin filament capping, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,11602704 0,14141898 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,11602704 0,14134737 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,11602704 0,14127584 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,11602704 0,14120438 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,11602704 0,14113299 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,11602704 0,14106168 ! hormone transport GO:0009914 40 23 0,000 0,11602704 0,14099043 ! cell-cell recognition GO:0009988 25 23 0,000 0,11602704 0,14091926 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,11602704 0,14084816 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,11602704 0,14077714 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,11602704 0,14070618 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,11602704 0,14063529 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12075621 0,14629378 GO:0016444|somatic cell DNA recombination, ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,12075621 0,14622015 ! vesicle docking GO:0048278 47 24 0,000 0,12075621 0,1461466 ! spinal cord development GO:0021510 47 24 0,000 0,12075621 0,14607312 ! vacuole organization GO:0007033 43 24 0,000 0,12075621 0,14599972 ! digestive system process GO:0022600 39 24 0,000 0,12075621 0,14592639 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,12075621 0,14585313 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,12075621 0,14577995 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,12075621 0,14570684 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12075621 0,14563381 ! membrane depolarization GO:0051899 39 24 0,000 0,12075621 0,14556084 ! pallium development GO:0021543 49 24 0,000 0,12075621 0,14548795 ! pentose metabolic process GO:0019321 35 24 0,000 0,12075621 0,14541514 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12075621 0,14534239 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12075621 0,14526972 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12075621 0,14519712 ! alditol metabolic process GO:0019400 38 24 0,000 0,12075621 0,1451246 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12075621 0,14505214 ! regulation of amine transport GO:0051952 40 24 0,000 0,12075621 0,14497976 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,12546024 0,15055228 ! myelination GO:0042552 45 25 0,000 0,12546024 0,15047723 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12546024 0,15040226 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,12546024 0,15032736 ! phototransduction GO:0007602 33 25 0,000 0,12546024 0,15025253 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,12546024 0,15017778 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,12546024 0,1501031 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,12546024 0,15002849 ! receptor metabolic process GO:0043112 46 25 0,000 0,12546024 0,14995396 ! chromosome condensation GO:0030261 45 25 0,000 0,12546024 0,14987951 ! osteoblast differentiation GO:0001649 60 25 0,000 0,12546024 0,14980513 ! neural crest cell development GO:0014032 54 25 0,000 0,12546024 0,14973082 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,12546024 0,14965658 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,12546024 0,14958242 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12546024 0,14950834 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,12546024 0,14943432 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,12546024 0,14936038 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,12546024 0,14928651 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,12546024 0,14921272 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12546024 0,149139 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,12546024 0,14906535 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,12546024 0,14899177 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12546024 0,14891827 ! telomere organization GO:0032200 43 25 0,000 0,12546024 0,14884484 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,12546024 0,14877148 GO:0060606|tube closure, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13013925 0,15424386 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13013925 0,15416792 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13013925 0,15409205 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13013925 0,15401625 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13013925 0,15394053 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13013925 0,15386488 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13013925 0,15378931 ! tube lumen formation GO:0035148 50 26 0,000 0,13013925 0,15371381 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,13013925 0,15363839 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13013925 0,15356304 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,13013925 0,15348776 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13013925 0,15341256 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13013925 0,15333743 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,13013925 0,15326238 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13013925 0,1531874 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13013925 0,15311249 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,13013925 0,15303765 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13013925 0,15296289 ! blastocyst development GO:0001824 49 26 0,000 0,13013925 0,1528882 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13013925 0,15281359 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,13013925 0,15273904 ! neuron fate commitment GO:0048663 48 27 0,000 0,13479339 0,15812427 ! iron ion transport GO:0006826 59 27 0,000 0,13479339 0,15804722 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,13479339 0,15797023 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13479339 0,15789332 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13479339 0,15781649 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13479339 0,15773973 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13479339 0,15766305 ! autophagy GO:0006914 41 27 0,000 0,13479339 0,15758644 ! primary neural tube formation GO:0014020 51 27 0,000 0,13479339 0,1575099 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,13479339 0,15743344 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13479339 0,15735705 ! glutathione metabolic process GO:0006749 39 27 0,000 0,13479339 0,15728074 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,13479339 0,1572045 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13479339 0,15712834 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,13942277 0,1624461 ! circadian rhythm GO:0007623 50 28 0,000 0,13942277 0,16236747 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,13942277 0,16228892 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,13942277 0,16221044 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,13942277 0,16213204 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,13942277 0,16205372 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,13942277 0,16197547 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,13942277 0,16189729 ! synaptogenesis GO:0007416 42 28 0,000 0,13942277 0,1618192 ! lipid oxidation GO:0034440 43 28 0,000 0,13942277 0,16174117 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,13942277 0,16166323 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,13942277 0,16158535 ! translational initiation GO:0006413 65 29 0,000 0,14402754 0,16684173 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,14402754 0,16676144 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,14402754 0,16668123 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,14402754 0,16660109 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,14402754 0,16652103 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,14402754 0,16644105 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,14402754 0,16636115 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,14402754 0,16628132 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 60 29 0,000 0,14402754 0,16620157 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,14402754 0,16612189 ! detection of light stimulus GO:0009583 38 29 0,000 0,14402754 0,1660423 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,14402754 0,16596277 ! regulation of coagulation GO:0050818 46 29 0,000 0,14402754 0,16588333 ! zinc ion transport GO:0006829 45 30 0,000 0,14860783 0,17107676 ! membrane docking GO:0022406 61 30 0,000 0,14860783 0,17099495 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,14860783 0,17091321 ! regulation of innate immune response GO:0045088 51 30 0,000 0,14860783 0,17083155 ! acute-phase response GO:0006953 49 30 0,000 0,14860783 0,17074997 ! myofibril assembly GO:0030239 47 30 0,000 0,14860783 0,17066846 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,14860783 0,17058704 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,14860783 0,17050569 ! phospholipid transport GO:0015914 51 30 0,000 0,14860783 0,17042442 ! ensheathment of neurons GO:0007272 57 30 0,000 0,14860783 0,17034323 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,14860783 0,17026211 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 48 30 0,000 0,14860783 0,17018107 ! eye morphogenesis GO:0048592 60 30 0,000 0,14860783 0,17010011 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,15316375 0,17523157 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,15316375 0,17514828 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,15316375 0,17506508 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,15316375 0,17498195 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,15316375 0,1748989 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,15316375 0,17481593 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,15316375 0,17473304 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,15316375 0,17465023 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,15316375 0,1745675 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,15316375 0,17448484 ! peptide transport GO:0015833 55 31 0,000 0,15316375 0,17440227 ! mesoderm formation GO:0001707 69 31 0,000 0,15316375 0,17431977 ! natural killer cell activation GO:0030101 45 31 0,000 0,15316375 0,17423735 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,15316375 0,174155 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,15316375 0,17407274 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,15316375 0,17399055 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,15769545 0,17905392 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15769545 0,17896946 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,15769545 0,17888508 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15769545 0,17880078 ! spliceosome assembly GO:0000245 67 32 0,000 0,15769545 0,17871656 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,15769545 0,17863242 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,15769545 0,17854835 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,15769545 0,17846437 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,15769545 0,17838047 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,15769545 0,17829664 ! muscle cell development GO:0055001 49 32 0,000 0,15769545 0,17821289 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15769545 0,17812923 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,15769545 0,17804564 ! peripheral nervous system development GO:0007422 64 32 0,000 0,15769545 0,17796213 ! BMP signaling pathway GO:0030509 64 32 0,000 0,15769545 0,17787869 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,15769545 0,17779534 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,15769545 0,17771206 ! gene silencing GO:0016458 65 32 0,000 0,15769545 0,17762886 ! protein targeting to membrane GO:0006612 68 33 0,000 0,16220305 0,18262074 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,16220305 0,18253533 ! ceramide metabolic process GO:0006672 64 33 0,000 0,16220305 0,18244999 ! formation of primary germ layer GO:0001704 72 33 0,000 0,16220305 0,18236473 ! cell fate specification GO:0001708 52 33 0,000 0,16220305 0,18227956 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,16220305 0,18219446 ! adult locomotory behavior GO:0008344 59 33 0,000 0,16220305 0,18210944 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,16220305 0,1820245 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,16220305 0,18193964 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,16668667 0,1868817 ! glial cell differentiation GO:0010001 63 34 0,000 0,16668667 0,18679466 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,16668667 0,18670769 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,16668667 0,18662081 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,16668667 0,18653401 ! mismatch repair GO:0006298 46 34 0,000 0,16668667 0,18644729 ! spermatid development GO:0007286 63 34 0,000 0,16668667 0,18636065 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,16668667 0,18627409 ! odontogenesis GO:0042476 66 35 0,000 0,17114645 0,19116915 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,17114645 0,19108044 ! telencephalon development GO:0021537 68 35 0,000 0,17114645 0,19099181 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,17114645 0,19090327 ! cytokine production GO:0001816 59 35 0,000 0,17114645 0,1908148 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,17114645 0,19072642 ! neural tube formation GO:0001841 67 35 0,000 0,17114645 0,19063812 ! vesicle localization GO:0051648 64 35 0,000 0,17114645 0,19054991 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,1755825 0,19539847 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,1755825 0,19530814 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,1755825 0,19521788 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,1755825 0,19512771 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,1755825 0,19503763 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,1755825 0,19494762 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,1755825 0,1948577 ! aerobic respiration GO:0009060 55 36 0,000 0,1755825 0,19476786 ! embryonic organ development GO:0048568 57 36 0,000 0,1755825 0,19467811 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,1755825 0,19458844 ! RNA export from nucleus GO:0006405 56 37 0,000 0,17999496 0,19938668 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,17999496 0,19929493 ! actomyosin structure organization GO:0031032 62 37 0,000 0,17999496 0,19920325 ! organic anion transport GO:0015711 68 37 0,000 0,17999496 0,19911167 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,17999496 0,19902016 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,17999496 0,19892874 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,17999496 0,19883741 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,18438395 0,20359238 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,18438395 0,20349898 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,18438395 0,20340568 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,18438395 0,20331246 ! lipid homeostasis GO:0055088 67 38 0,000 0,18438395 0,20321932 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,18438395 0,20312628 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,18438395 0,20303331 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,18438395 0,20294043 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,18438395 0,20284764 ! mRNA catabolic process GO:0006402 71 39 0,000 0,18874959 0,20755554 ! mammary gland development GO:0030879 86 39 0,000 0,18874959 0,20746072 ! ear morphogenesis GO:0042471 60 39 0,000 0,18874959 0,20736599 ! ion transmembrane transport GO:0034220 66 39 0,000 0,18874959 0,20727135 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,18874959 0,20717679 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,18874959 0,20708232 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,18874959 0,20698793 ! RNA modification GO:0009451 57 39 0,000 0,18874959 0,20689363 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,18874959 0,20679942 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,19309201 0,2114608 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,19309201 0,2113646 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,19309201 0,21126848 ! feeding behavior GO:0007631 59 40 0,000 0,19309201 0,21117245 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,19309201 0,2110765 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,19309201 0,21098065 ! maintenance of protein location GO:0045185 91 40 0,000 0,19309201 0,21088488 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,19741133 0,21550439 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,19741133 0,21540665 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,19741133 0,21530901 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,19741133 0,21521145 ! gliogenesis GO:0042063 88 41 0,000 0,19741133 0,21511398 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,19741133 0,2150166 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,19741133 0,21491931 ! polyol metabolic process GO:0019751 66 41 0,000 0,19741133 0,2148221 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,19741133 0,21472499 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,20170768 0,21929899 ! regulation of tube size GO:0035150 71 42 0,000 0,20170768 0,21919994 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,20170768 0,21910098 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,20170768 0,21900211 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,20170768 0,21890332 ! neuron migration GO:0001764 79 42 0,000 0,20170768 0,21880463 ! regulation of protein secretion GO:0050708 71 42 0,000 0,20170768 0,21870602 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,20598116 0,22323904 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,20598116 0,22313853 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,20598116 0,22303811 ! neural tube development GO:0021915 77 43 0,000 0,20598116 0,22293777 ! striated muscle contraction GO:0006941 77 43 0,000 0,20598116 0,22283753 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,20598116 0,22273738 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,21023191 0,2272318 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,21023191 0,22712976 ! biopolymer methylation GO:0043414 84 44 0,000 0,21023191 0,22702782 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,21023191 0,22692596 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,21023191 0,2268242 ! maintenance of location in cell GO:0051651 97 44 0,000 0,21023191 0,22672254 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,21446004 0,2311787 ! glycolysis GO:0006096 65 45 0,000 0,21446004 0,23107517 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,21446004 0,23097174 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,21446004 0,2308684 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,21446004 0,23076515 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,21446004 0,23066199 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,21446004 0,23055892 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,21866568 0,23497527 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,21866568 0,23487037 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,21866568 0,23476556 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,21866568 0,23466085 ! endosome transport GO:0016197 108 47 0,000 0,22284894 0,23904349 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,22284894 0,23893697 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,22284894 0,23883054 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,22284894 0,2387242 ! methylation GO:0032259 90 47 0,000 0,22284894 0,23861796 ! Notch signaling pathway GO:0007219 96 48 0,000 0,22700994 0,24296527 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,22700994 0,24285724 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,22700994 0,2427493 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,22700994 0,24264146 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,2311488 0,24695561 ! regulation of action potential GO:0001508 95 49 0,000 0,2311488 0,24684599 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,2311488 0,24673648 ! regulation of ion transport GO:0043269 77 49 0,000 0,2311488 0,24662706 ! peptide metabolic process GO:0006518 76 49 0,000 0,2311488 0,24651774 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,2311488 0,24640852 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,2311488 0,24629939 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,2311488 0,24619036 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,2311488 0,24608143 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,2311488 0,24597259 ! neuromuscular process GO:0050905 99 50 0,000 0,23526564 0,25024276 ! inner ear development GO:0048839 79 50 0,000 0,23526564 0,25013218 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,23526564 0,2500217 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,23526564 0,24991132 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,23936057 0,25414895 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,23936057 0,25403685 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,23936057 0,25392484 ! chromatin remodeling GO:0006338 109 51 0,000 0,23936057 0,25381293 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,23936057 0,25370111 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,23936057 0,2535894 ! membrane fusion GO:0006944 110 52 0,000 0,24343371 0,25779115 ! amino acid activation GO:0043038 92 52 0,000 0,24343371 0,25767774 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,24343371 0,25756442 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,24748517 0,26173596 ! RNA catabolic process GO:0006401 93 53 0,000 0,24748517 0,26162096 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,24748517 0,26150607 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,24748517 0,26139127 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,24748517 0,26127657 ! cell maturation GO:0048469 100 53 0,000 0,24748517 0,26116198 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,24748517 0,26104749 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,25151507 0,26518197 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,25151507 0,26506581 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,25151507 0,26494976 ! cell recognition GO:0008037 85 54 0,000 0,25151507 0,26483381 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,25151507 0,26471796 ! chloride transport GO:0006821 90 55 0,000 0,25552352 0,26881923 ! glucose catabolic process GO:0006007 82 55 0,000 0,25552352 0,26870174 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,25552352 0,26858435 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,25552352 0,26846707 ! gastrulation GO:0007369 112 55 0,000 0,25552352 0,26834988 ! RNA elongation GO:0006354 79 55 0,000 0,25552352 0,2682328 ! regulation of actin filament length GO:0030832 105 56 0,000 0,25951064 0,27229943 ! sensory perception of smell GO:0007608 80 56 0,000 0,25951064 0,27218073 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,25951064 0,27206213 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,25951064 0,27194364 ! proton transport GO:0015992 94 56 0,000 0,25951064 0,27182525 ! muscle fiber development GO:0048747 112 57 0,000 0,26347653 0,27585924 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,26347653 0,27573925 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,26347653 0,27561936 ! hydrogen transport GO:0006818 97 58 0,000 0,26742132 0,27962438 ! adult behavior GO:0030534 99 58 0,000 0,26742132 0,27950291 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,26742132 0,27938154 ! positive regulation of secretion GO:0051047 95 59 0,000 0,27134511 0,28335778 ! regulation of cellular component size GO:0032535 109 59 0,000 0,27134511 0,28323485 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,27134511 0,28311202 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,27134511 0,2829893 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,27134511 0,28286669 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,27524801 0,28681105 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,27524801 0,28668689 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,27913014 0,29060455 ! mesoderm development GO:0007498 119 61 0,000 0,27913014 0,29047885 ! tRNA processing GO:0008033 89 61 0,000 0,27913014 0,29035327 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,27913014 0,29022779 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,2829916 0,29411567 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,2868325 0,29797884 ! detection of external stimulus GO:0009581 91 63 0,000 0,2868325 0,29785023 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,2868325 0,29772174 ! cell redox homeostasis GO:0045454 102 64 0,000 0,29065295 0,30155714 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,29065295 0,30142716 ! single fertilization GO:0007338 75 64 0,000 0,29065295 0,30129729 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,29445307 0,30510512 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,29445307 0,30497378 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,29823295 0,3087558 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,29823295 0,308623 ! extracellular matrix organization GO:0030198 133 66 0,000 0,29823295 0,30849032 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,30199271 0,31224515 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,30199271 0,31211102 ! hexose catabolic process GO:0019320 104 67 0,000 0,30199271 0,31197701 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,30199271 0,31184312 ! activation of immune response GO:0002253 105 67 0,000 0,30199271 0,31170934 ! amino acid transport GO:0006865 125 68 0,000 0,30573245 0,31543408 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,30573245 0,31529888 ! regulation of lipase activity GO:0060191 130 68 0,000 0,30573245 0,31516379 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,30573245 0,31502881 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,30945228 0,31872525 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,30945228 0,31858887 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,30945228 0,3184526 ! appendage morphogenesis GO:0035107 135 70 0,000 0,3131523 0,32212246 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,31683261 0,32576892 ! appendage development GO:0048736 136 71 0,000 0,31683261 0,32562976 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,31683261 0,32549072 ! acute inflammatory response GO:0002526 113 72 0,000 0,32049333 0,32911095 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,32413456 0,33270808 ! axon guidance GO:0007411 139 73 0,000 0,32413456 0,3325662 ! fertilization GO:0009566 90 73 0,000 0,32413456 0,33242444 ! transition metal ion transport GO:0000041 126 74 0,000 0,32775639 0,33599568 ! neurotransmitter transport GO:0006836 123 74 0,000 0,32775639 0,33585259 ! exocytosis GO:0006887 133 74 0,000 0,32775639 0,33570961 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,32775639 0,33556675 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,32775639 0,33542402 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,33135893 0,33896666 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,33135893 0,33882261 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,33494229 0,34234118 ! defense response to bacterium GO:0042742 89 76 0,000 0,33494229 0,34219582 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,33494229 0,34205057 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,33494229 0,34190545 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,33850656 0,34539728 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,33850656 0,34525086 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,34205185 0,34871896 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,34557825 0,35216488 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,34557825 0,35201578 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,34557825 0,35186681 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,34908587 0,35528791 ! inorganic anion transport GO:0015698 138 80 0,000 0,34908587 0,35513768 ! digestion GO:0007586 112 81 0,000 0,35257481 0,3585355 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,35257481 0,35838403 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,35604516 0,36175872 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,35604516 0,36160602 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,35604516 0,36145344 ! regulation of lyase activity GO:0051339 160 83 0,000 0,35949702 0,36480381 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,3629305 0,36813271 ! nucleosome assembly GO:0006334 122 85 0,000 0,36634568 0,37144025 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,36634568 0,37128379 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,36974267 0,37456879 ! chromatin assembly GO:0031497 124 86 0,000 0,36974267 0,37441114 ! alcohol catabolic process GO:0046164 130 86 0,000 0,36974267 0,37425362 ! amine transport GO:0015837 155 86 0,000 0,36974267 0,37409624 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,37312156 0,37735623 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of protein transport GO:0051223 154 87 0,000 0,37312156 0,37719768 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,37648245 0,38043543 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,37648245 0,38027572 ! cellular defense response GO:0006968 114 89 0,000 0,37982543 0,38349139 ! ossification GO:0001503 188 90 0,000 0,38315059 0,38668638 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,38315059 0,38652425 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,38315059 0,38636225 ! bone development GO:0060348 189 91 0,000 0,38645804 0,38953416 ! sterol metabolic process GO:0016125 152 91 0,000 0,38645804 0,38937104 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,38645804 0,38920806 ! nucleosome organization GO:0034728 138 92 0,000 0,38974786 0,39235706 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,38974786 0,39219296 ! vitamin metabolic process GO:0006766 139 92 0,000 0,38974786 0,392029 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,39302016 0,39515524 ! transcription initiation GO:0006352 153 94 0,000 0,39627501 0,39826135 ! forebrain development GO:0030900 188 95 0,000 0,39951252 0,40134744 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,39951252 0,40117994 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,40273278 0,40424491 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,40273278 0,40407634 ! positive regulation of immune response GO:0050778 156 96 0,000 0,40273278 0,4039079 ! detection of stimulus GO:0051606 151 96 0,000 0,40273278 0,40373961 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,40593587 0,40678122 ! hormone metabolic process GO:0042445 157 97 0,000 0,40593587 0,40661186 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,40912189 0,40963265 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,40912189 0,40946226 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,41229093 0,41246236 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,41229093 0,41229093