pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1135-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 5,000 3,216E-12 7,738E-09 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 4,000 4,62E-08 5,557E-05 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 6,000 6,304E-08 5,056E-05 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 6,000 8,499E-08 5,112E-05 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 6,000 8,499E-08 4,09E-05 ! positive regulation of ligase activity GO:0051351 124 77 6,000 1,358E-07 5,447E-05 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 6,000 1,623E-07 5,58E-05 ! regulation of ligase activity GO:0051340 142 84 6,000 2,483E-07 7,469E-05 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 1,211E-06 3,239E-04 ! regulation of leukocyte degranulation GO:0043300 7 5 2,000 1,276E-06 3,07E-04 ! positive regulation of mast cell activation GO:0033005 11 5 2,000 1,276E-06 2,791E-04 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 5,000 1,315E-06 2,637E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 1,448E-06 2,679E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 2,543E-06 4,37E-04 ! nuclear migration GO:0007097 12 6 2,000 2,543E-06 4,078E-04 ! positive regulation of exocytosis GO:0045921 8 6 2,000 2,543E-06 3,823E-04 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 2,000 2,543E-06 3,598E-04 ! regulation of mast cell activation GO:0033003 12 6 2,000 2,543E-06 3,399E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 2,543E-06 3,22E-04 GO:0031272|regulation of pseudopodium assembly, ! response to insulin stimulus GO:0032868 95 46 4,000 3,672E-06 4,417E-04 ! cellular response to hormone stimulus GO:0032870 167 82 5,000 3,968E-06 4,546E-04 ! calcium-independent cell-cell adhesion GO:0016338 30 22 3,000 4,362E-06 4,77E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 4,433E-06 4,637E-04 ! macrophage differentiation GO:0030225 11 7 2,000 4,433E-06 4,444E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 7,066E-06 6,8E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 7,066E-06 6,539E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 7,066E-06 6,297E-04 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 5,000 8,25E-06 7,089E-04 GO:0010498|proteasomal protein catabolic process, ! insulin receptor signaling pathway GO:0008286 64 26 3,000 8,775E-06 7,28E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,056E-05 8,469E-04 ! positive regulation of secretion GO:0051047 95 59 4,000 1,272E-05 9,87E-04 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 1,382E-05 1,039E-03 ! regulation of protein complex assembly GO:0043254 117 61 4,000 1,499E-05 1,093E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 1,499E-05 1,061E-03 ! phagocytosis, engulfment GO:0006911 28 10 2,000 1,503E-05 1,033E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 2,059E-05 1,376E-03 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 2,059E-05 1,339E-03 ! nucleus localization GO:0051647 19 11 2,000 2,059E-05 1,304E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 4,000 2,374E-05 1,465E-03 ! negative regulation of ligase activity GO:0051352 112 68 4,000 2,552E-05 1,535E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 2,735E-05 1,605E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 2,735E-05 1,567E-03 ! regulation of hormone metabolic process GO:0032350 26 12 2,000 2,735E-05 1,53E-03 ! lipid localization GO:0010876 28 13 2,000 3,542E-05 1,937E-03 GO:0019915|lipid storage, ! cellular carbohydrate catabolic process GO:0044275 15 13 2,000 3,542E-05 1,894E-03 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 3,542E-05 1,853E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 4,132E-05 2,115E-03 GO:0042593|glucose homeostasis, ! regulation of exocytosis GO:0017157 22 15 2,000 5,593E-05 2,804E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 5,593E-05 2,746E-03 ! energy reserve metabolic process GO:0006112 74 43 3,000 6,773E-05 3,259E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 6,773E-05 3,195E-03 ! filopodium assembly GO:0046847 32 16 2,000 6,858E-05 3,173E-03 ! myoblast differentiation GO:0045445 45 17 2,000 8,297E-05 3,766E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 8,297E-05 3,697E-03 ! microspike assembly GO:0030035 36 17 2,000 8,297E-05 3,629E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 9,919E-05 4,262E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 9,919E-05 4,187E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 1,173E-04 4,868E-03 ! regulation of ossification GO:0030278 117 50 3,000 1,23E-04 5,014E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 1,375E-04 5,516E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 1,375E-04 5,425E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! pancreas development GO:0031016 35 20 2,000 1,375E-04 5,338E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 1,375E-04 5,253E-03 ! skeletal muscle tissue development GO:0007519 186 99 4,000 1,543E-04 5,802E-03 GO:0060538|skeletal muscle organ development, ! phosphatidylinositol metabolic process GO:0046488 36 21 2,000 1,599E-04 5,918E-03 ! positive regulation of osteoblast differentiation GO:0045669 49 21 2,000 1,599E-04 5,828E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,844E-04 6,623E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 1,844E-04 6,525E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 1,844E-04 6,431E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 2,052E-04 7,052E-03 ! regulation of bone remodeling GO:0046850 137 57 3,000 2,052E-04 6,952E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 2,113E-04 7,061E-03 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 2,000 2,113E-04 6,964E-03 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of tissue remodeling GO:0034103 140 58 3,000 2,195E-04 7,136E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 2,406E-04 7,718E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 2,406E-04 7,616E-03 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 1,000 2,538E-04 7,932E-03 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,538E-04 7,83E-03 ! anagen GO:0042640 6 5 1,000 2,538E-04 7,731E-03 ! microvillus organization GO:0032528 7 5 1,000 2,538E-04 7,634E-03 GO:0030033|microvillus assembly, ! polyol catabolic process GO:0046174 7 5 1,000 2,538E-04 7,54E-03 GO:0019405|alditol catabolic process, ! response to food GO:0032094 6 5 1,000 2,538E-04 7,448E-03 ! regulation of glycogen metabolic process GO:0070873 11 5 1,000 2,538E-04 7,358E-03 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,538E-04 7,271E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 2,538E-04 7,185E-03 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 1,000 2,538E-04 7,102E-03 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 2,538E-04 7,02E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 2,538E-04 6,94E-03 GO:0051930|regulation of sensory perception of pain, ! cellular anion homeostasis GO:0030002 9 5 1,000 2,538E-04 6,862E-03 GO:0055081|anion homeostasis, ! vasculogenesis GO:0001570 46 25 2,000 2,724E-04 7,282E-03 ! regulation of insulin secretion GO:0050796 37 25 2,000 2,724E-04 7,202E-03 ! interaction with host GO:0051701 62 25 2,000 2,724E-04 7,123E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 2,724E-04 7,047E-03 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 3,022E-04 7,734E-03 ! regulation of osteoblast differentiation GO:0045667 65 26 2,000 3,068E-04 7,769E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 3,438E-04 8,617E-03 ! fat cell differentiation GO:0045444 50 27 2,000 3,438E-04 8,528E-03 ! cell projection assembly GO:0030031 120 66 3,000 3,613E-04 8,87E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 3,795E-04 9,223E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 3,795E-04 9,131E-03 ! male sex determination GO:0030238 15 6 1,000 3,795E-04 9,04E-03 ! positive regulation of cytokine production during immune response GO:0002720 9 6 1,000 3,795E-04 8,952E-03 ! positive regulation of B cell differentiation GO:0045579 11 6 1,000 3,795E-04 8,865E-03 ! hair follicle maturation GO:0048820 7 6 1,000 3,795E-04 8,779E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 3,795E-04 8,696E-03 ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 1,000 3,795E-04 8,614E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 3,795E-04 8,533E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 3,827E-04 8,527E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 4,263E-04 9,411E-03 ! regulation of peptide secretion GO:0002791 47 29 2,000 4,263E-04 9,325E-03 ! immune response-activating signal transduction GO:0002757 47 29 2,000 4,263E-04 9,241E-03 GO:0002764|immune response-regulating signal transduction, ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 4,263E-04 9,158E-03 ! negative regulation of neuron apoptosis GO:0043524 56 29 2,000 4,263E-04 9,077E-03 ! regulation of MAPKKK cascade GO:0043408 142 71 3,000 4,776E-04 0,01008015 ! phosphoinositide metabolic process GO:0030384 128 72 3,000 5,037E-04 0,01053881 ! positive regulation of immune effector process GO:0002699 67 31 2,000 5,206E-04 0,01079724 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,295E-04 0,01088905 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 5,295E-04 0,01079677 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 5,295E-04 0,01070604 ! regulation of dopamine metabolic process GO:0042053 11 7 1,000 5,295E-04 0,01061682 GO:0042069|regulation of catecholamine metabolic process, ! vesicle fusion GO:0006906 17 7 1,000 5,295E-04 0,01052908 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 1,000 5,295E-04 0,01044278 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 1,000 5,295E-04 0,01035788 ! regulation of interleukin-10 production GO:0032653 13 7 1,000 5,295E-04 0,01027435 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 1,000 5,295E-04 0,01019215 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 5,295E-04 0,01011126 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 1,000 5,295E-04 0,01003164 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of respiratory burst GO:0060263 11 7 1,000 5,295E-04 9,953E-03 ! dopamine biosynthetic process GO:0042416 18 7 1,000 5,295E-04 9,876E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 5,295E-04 9,8E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 5,295E-04 9,725E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 5,723E-04 0,01043119 ! leukocyte chemotaxis GO:0030595 50 33 2,000 6,272E-04 0,01134577 GO:0060326|cell chemotaxis, ! protein oligomerization GO:0051259 139 78 3,000 6,822E-04 0,01224833 ! placenta development GO:0001890 53 34 2,000 6,853E-04 0,01221391 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 6,853E-04 0,0121241 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 1,000 7,037E-04 0,01235784 ! regulation of cellular amine metabolic process GO:0033238 12 8 1,000 7,037E-04 0,0122683 ! ER overload response GO:0006983 12 8 1,000 7,037E-04 0,01218003 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 1,000 7,037E-04 0,01209303 ! regulation of fat cell differentiation GO:0045598 15 8 1,000 7,037E-04 0,01200727 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 7,037E-04 0,01192271 ! mast cell activation GO:0045576 14 8 1,000 7,037E-04 0,01183933 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 7,037E-04 0,01175712 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 7,157E-04 0,01187614 ! regulation of microtubule-based process GO:0032886 78 35 2,000 7,468E-04 0,01230665 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 7,863E-04 0,01287031 GO:0045937|positive regulation of phosphate metabolic process, ! androgen receptor signaling pathway GO:0030521 74 36 2,000 8,117E-04 0,01319489 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 8,8E-04 0,01420989 ! tissue remodeling GO:0048771 76 37 2,000 8,8E-04 0,01411516 ! glycerol ether metabolic process GO:0006662 53 37 2,000 8,8E-04 0,01402168 ! glycogen metabolic process GO:0005977 61 37 2,000 8,8E-04 0,01392943 ! regulation of developmental growth GO:0048638 15 9 1,000 9,017E-04 0,01417965 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 9,017E-04 0,01408758 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 9,017E-04 0,01399669 ! regulation of glycolysis GO:0006110 21 9 1,000 9,017E-04 0,01390697 ! T cell selection GO:0045058 23 9 1,000 9,017E-04 0,01381839 ! protein heterooligomerization GO:0051291 16 9 1,000 9,017E-04 0,01373093 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 9,017E-04 0,01364457 ! gas homeostasis GO:0033483 16 9 1,000 9,017E-04 0,01355929 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 9,017E-04 0,01347507 ! induction of an organ GO:0001759 14 9 1,000 9,017E-04 0,0133919 ! glucan metabolic process GO:0044042 62 38 2,000 9,519E-04 0,01405051 GO:0006073|cellular glucan metabolic process, ! organic ether metabolic process GO:0018904 55 39 2,000 1,027E-03 0,0150725 ! regulation of hormone secretion GO:0046883 62 40 2,000 1,107E-03 0,01613584 ! mesenchymal cell development GO:0014031 87 40 2,000 1,107E-03 0,01603863 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 1,123E-03 0,01618454 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,123E-03 0,01608821 GO:0005978|glycogen biosynthetic process, ! central nervous system neuron axonogenesis GO:0021955 22 10 1,000 1,123E-03 0,01599301 GO:0021952|central nervous system projection neuron axonogenesis, ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,123E-03 0,01589893 ! positive regulation of phagocytosis GO:0050766 13 10 1,000 1,123E-03 0,01580596 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 1,000 1,123E-03 0,01571406 ! regulation of B cell differentiation GO:0045577 19 10 1,000 1,123E-03 0,01562323 ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 1,123E-03 0,01553344 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,123E-03 0,01544468 ! positive regulation of acute inflammatory response GO:0002675 16 10 1,000 1,123E-03 0,01535693 ! midbrain development GO:0030901 13 10 1,000 1,123E-03 0,01527016 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,123E-03 0,01518438 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 1,123E-03 0,01509955 ! ossification GO:0001503 188 90 3,000 1,166E-03 0,01558299 ! bone development GO:0060348 189 91 3,000 1,215E-03 0,01614603 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,276E-03 0,01687197 ! regulation of leukocyte mediated immunity GO:0002703 79 42 2,000 1,276E-03 0,01677978 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,317E-03 0,01721565 ! phagocytosis GO:0006909 90 43 2,000 1,367E-03 0,01777718 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,368E-03 0,01770128 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,368E-03 0,01760662 ! adult heart development GO:0007512 14 11 1,000 1,368E-03 0,01751297 ! negative regulation of ossification GO:0030279 26 11 1,000 1,368E-03 0,01742031 ! negative regulation of glucose import GO:0046325 17 11 1,000 1,368E-03 0,01732862 GO:0010829|negative regulation of glucose transport, ! developmental induction GO:0031128 19 11 1,000 1,368E-03 0,01723789 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 1,368E-03 0,01714811 ! leukocyte differentiation GO:0002521 202 96 3,000 1,48E-03 0,01845589 ! leukocyte migration GO:0050900 68 45 2,000 1,56E-03 0,01934836 ! virus-host interaction GO:0019048 29 12 1,000 1,637E-03 0,02019367 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,637E-03 0,02009064 ! entry into host cell GO:0030260 32 12 1,000 1,637E-03 0,01998866 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 1,000 1,637E-03 0,0198877 ! regulation of phagocytosis GO:0050764 16 12 1,000 1,637E-03 0,01978777 ! histone acetylation GO:0016573 26 12 1,000 1,637E-03 0,01968883 ! gland morphogenesis GO:0022612 29 12 1,000 1,637E-03 0,01959087 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,637E-03 0,01949389 ! T cell homeostasis GO:0043029 25 12 1,000 1,637E-03 0,01939786 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 1,000 1,637E-03 0,01930277 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,663E-03 0,01951513 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,663E-03 0,0194204 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,663E-03 0,01932658 ! response to calcium ion GO:0051592 81 47 2,000 1,77E-03 0,02046905 ! regulation of JNK cascade GO:0046328 94 47 2,000 1,77E-03 0,02037112 ! protein homooligomerization GO:0051260 76 47 2,000 1,77E-03 0,02027411 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,881E-03 0,02144363 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 1,881E-03 0,02134248 ! organelle fusion GO:0048284 32 13 1,000 1,928E-03 0,02177572 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,928E-03 0,02167396 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cytokine production during immune response GO:0002718 23 13 1,000 1,928E-03 0,02157315 ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 1,928E-03 0,02147328 ! regulation of acute inflammatory response GO:0002673 21 13 1,000 1,928E-03 0,02137432 ! regulation of calcium-mediated signaling GO:0050848 25 13 1,000 1,928E-03 0,02127628 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 1,928E-03 0,02117912 ! regulation of cell projection organization GO:0031344 121 50 2,000 2,115E-03 0,02313404 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 2,239E-03 0,02437827 ! regulation of cell shape GO:0008360 125 51 2,000 2,239E-03 0,02426845 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,242E-03 0,02418501 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 2,242E-03 0,02407704 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 2,242E-03 0,02397003 ! positive regulation of growth GO:0045927 90 52 2,000 2,368E-03 0,02520498 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 2,5E-03 0,02650133 ! regulation of protein polymerization GO:0032271 103 53 2,000 2,5E-03 0,02638509 ! response to UV GO:0009411 104 53 2,000 2,5E-03 0,02626987 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 2,578E-03 0,02696646 ! regulation of vasodilation GO:0042312 26 15 1,000 2,578E-03 0,02684972 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,578E-03 0,02673399 ! dopamine metabolic process GO:0042417 35 15 1,000 2,578E-03 0,02661925 ! lymphocyte homeostasis GO:0002260 30 15 1,000 2,578E-03 0,02650549 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 2,78E-03 0,0284574 ! skeletal muscle fiber development GO:0048741 111 56 2,000 2,926E-03 0,02983028 ! nucleotide-excision repair GO:0006289 83 56 2,000 2,926E-03 0,02970441 ! regulation of DNA replication GO:0006275 101 56 2,000 2,926E-03 0,0295796 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,936E-03 0,02955964 ! startle response GO:0001964 28 16 1,000 2,936E-03 0,02943647 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 2,936E-03 0,02931433 ! fructose metabolic process GO:0006000 25 16 1,000 2,936E-03 0,0291932 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 2,936E-03 0,02907306 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,936E-03 0,02895391 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 2,936E-03 0,02883573 ! bone remodeling GO:0046849 27 16 1,000 2,936E-03 0,02871851 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 2,936E-03 0,02860224 GO:0031114|regulation of microtubule depolymerization, ! muscle fiber development GO:0048747 112 57 2,000 3,077E-03 0,02985335 ! positive regulation of cell migration GO:0030335 126 57 2,000 3,077E-03 0,02973346 ! regulation of intracellular transport GO:0032386 101 57 2,000 3,077E-03 0,02961452 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 3,317E-03 0,03179325 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,317E-03 0,03166708 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 1,000 3,317E-03 0,03154192 GO:0002712|regulation of B cell mediated immunity, ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 3,317E-03 0,03141774 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 3,317E-03 0,03129453 ! establishment of organelle localization GO:0051656 109 59 2,000 3,394E-03 0,0318951 ! neuron maturation GO:0042551 42 18 1,000 3,719E-03 0,03481629 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 3,719E-03 0,03468134 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 3,719E-03 0,03454744 ! positive regulation of proteolysis GO:0045862 31 18 1,000 3,719E-03 0,03441456 ! glutamine metabolic process GO:0006541 29 18 1,000 3,719E-03 0,03428271 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 3,719E-03 0,03415186 ! mesoderm development GO:0007498 119 61 2,000 3,729E-03 0,03411754 ! viral reproductive process GO:0022415 126 62 2,000 3,905E-03 0,03558488 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 4,085E-03 0,03708596 ! lipid phosphorylation GO:0046834 35 19 1,000 4,143E-03 0,03747087 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 4,143E-03 0,03733053 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 4,143E-03 0,03719123 ! positive regulation of cell motion GO:0051272 146 64 2,000 4,27E-03 0,03819006 ! myeloid cell differentiation GO:0030099 111 65 2,000 4,46E-03 0,03974275 ! protein amino acid acetylation GO:0006473 39 20 1,000 4,588E-03 0,04073045 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 4,588E-03 0,04058071 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 4,588E-03 0,04043206 ! leukotriene biosynthetic process GO:0019370 37 20 1,000 4,588E-03 0,0402845 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 29 20 1,000 4,588E-03 0,04013801 GO:0010827|regulation of glucose transport, ! developmental maturation GO:0021700 116 66 2,000 4,655E-03 0,04058017 ! regulation of cellular response to stress GO:0080135 128 67 2,000 4,855E-03 0,04217316 ! activation of MAPK activity GO:0000187 115 67 2,000 4,855E-03 0,04202146 ! lung development GO:0030324 144 67 2,000 4,855E-03 0,04187085 ! activation of immune response GO:0002253 105 67 2,000 4,855E-03 0,04172131 ! glycerol metabolic process GO:0006071 34 21 1,000 5,054E-03 0,04327172 ! inactivation of MAPK activity GO:0000188 39 21 1,000 5,054E-03 0,04311827 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 5,054E-03 0,04296591 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 5,054E-03 0,04281462 ! regulation of vasoconstriction GO:0019229 39 21 1,000 5,054E-03 0,0426644 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 5,054E-03 0,04251522 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 5,061E-03 0,04242562 ! viral reproduction GO:0016032 134 68 2,000 5,061E-03 0,04227831 ! negative regulation of cell size GO:0045792 134 69 2,000 5,271E-03 0,04388503 ! respiratory tube development GO:0030323 150 70 2,000 5,487E-03 0,04552384 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 5,541E-03 0,04581071 ! microtubule-based transport GO:0010970 54 22 1,000 5,541E-03 0,04565382 ! central nervous system neuron development GO:0021954 46 22 1,000 5,541E-03 0,04549801 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 5,541E-03 0,04534325 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 5,541E-03 0,04518955 ! positive regulation of B cell activation GO:0050871 38 22 1,000 5,541E-03 0,04503688 ! activation of JUN kinase activity GO:0007257 42 22 1,000 5,541E-03 0,04488524 ! regulation of immune effector process GO:0002697 137 71 2,000 5,708E-03 0,04608609 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 5,934E-03 0,04775276 ! respiratory system development GO:0060541 153 72 2,000 5,934E-03 0,04759358 ! positive regulation of DNA replication GO:0045740 43 23 1,000 6,048E-03 0,04834588 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 6,048E-03 0,04818579 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 6,048E-03 0,04802676 ! leukocyte adhesion GO:0007159 50 23 1,000 6,048E-03 0,04786878 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 6,048E-03 0,04771183 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 6,048E-03 0,04755591 ! sex determination GO:0007530 47 23 1,000 6,048E-03 0,04740101 ! leukotriene metabolic process GO:0006691 42 23 1,000 6,048E-03 0,04724711 ! regulation of interleukin-6 production GO:0032675 29 23 1,000 6,048E-03 0,0470942 ! regulation of bone mineralization GO:0030500 49 23 1,000 6,048E-03 0,04694229 ! organelle localization GO:0051640 136 74 2,000 6,403E-03 0,04953463 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 6,576E-03 0,05071284 ! vesicle docking GO:0048278 47 24 1,000 6,576E-03 0,05055082 ! central nervous system neuron differentiation GO:0021953 50 24 1,000 6,576E-03 0,05038983 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 6,576E-03 0,05022986 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 6,576E-03 0,0500709 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 1,000 6,576E-03 0,04991295 ! regulation of tumor necrosis factor production GO:0032680 34 24 1,000 6,576E-03 0,04975599 ! membrane depolarization GO:0051899 39 24 1,000 6,576E-03 0,04960002 ! leukocyte homeostasis GO:0001776 44 24 1,000 6,576E-03 0,04944502 ! cellular alkene metabolic process GO:0043449 43 24 1,000 6,576E-03 0,04929098 ! alditol metabolic process GO:0019400 38 24 1,000 6,576E-03 0,0491379 ! protein tetramerization GO:0051262 52 24 1,000 6,576E-03 0,04898577 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 6,645E-03 0,04934628 ! regulation of vesicle-mediated transport GO:0060627 119 75 2,000 6,645E-03 0,04919445 ! defense response to bacterium GO:0042742 89 76 2,000 6,893E-03 0,05087147 ! regulation of catabolic process GO:0009894 161 76 2,000 6,893E-03 0,0507159 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 7,124E-03 0,05226 ! osteoblast differentiation GO:0001649 60 25 1,000 7,124E-03 0,05210116 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 7,124E-03 0,05194327 ! regulation of biomineral formation GO:0070167 51 25 1,000 7,124E-03 0,05178635 ! somitogenesis GO:0001756 43 25 1,000 7,124E-03 0,05163036 ! regulation of blood coagulation GO:0030193 40 25 1,000 7,124E-03 0,05147532 ! regulation of peptidase activity GO:0052547 134 79 2,000 7,668E-03 0,05524065 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 1,000 7,693E-03 0,0552484 ! embryonic pattern specification GO:0009880 44 26 1,000 7,693E-03 0,05508397 ! initiation of viral infection GO:0019059 57 26 1,000 7,693E-03 0,05492052 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 7,693E-03 0,05475803 ! molting cycle process GO:0022404 50 26 1,000 7,693E-03 0,0545965 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 7,693E-03 0,05443593 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 7,693E-03 0,05427629 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 7,693E-03 0,05411759 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 7,693E-03 0,05395981 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 7,693E-03 0,05380295 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 7,693E-03 0,053647 ! response to metal ion GO:0010038 140 80 2,000 7,938E-03 0,05519907 ! muscle cell differentiation GO:0042692 159 80 2,000 7,938E-03 0,05503999 ! response to hypoxia GO:0001666 171 81 2,000 8,213E-03 0,05678357 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 8,28E-03 0,05708508 ! protein amino acid acylation GO:0043543 55 27 1,000 8,28E-03 0,05692198 ! base-excision repair GO:0006284 41 27 1,000 8,28E-03 0,05675981 ! response to oxygen levels GO:0070482 176 83 2,000 8,78E-03 0,06001264 ! negative regulation of protein modification process GO:0031400 60 28 1,000 8,888E-03 0,06057848 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 8,888E-03 0,06040735 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 8,888E-03 0,06023719 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 8,888E-03 0,06006798 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 8,888E-03 0,05989973 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 8,888E-03 0,05973241 ! nucleosome assembly GO:0006334 122 85 2,000 9,369E-03 0,06279144 ! positive regulation of cell activation GO:0050867 145 85 2,000 9,369E-03 0,06261701 GO:0002696|positive regulation of leukocyte activation, ! icosanoid biosynthetic process GO:0046456 54 29 1,000 9,515E-03 0,0634134 ! catechol metabolic process GO:0009712 54 29 1,000 9,515E-03 0,06323822 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 9,515E-03 0,06306401 ! regulation of coagulation GO:0050818 46 29 1,000 9,515E-03 0,06289076 ! response to inorganic substance GO:0010035 153 86 2,000 9,672E-03 0,06375702 ! chromatin assembly GO:0031497 124 86 2,000 9,672E-03 0,06358282 ! regulation of protein transport GO:0051223 154 87 2,000 9,981E-03 0,06543361 GO:0070201|regulation of establishment of protein localization, ! phenol metabolic process GO:0018958 55 30 1,000 0,01016055 0,06643013 ! membrane docking GO:0022406 61 30 1,000 0,01016055 0,06625011 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 0,01016055 0,06607105 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01016055 0,06589296 ! regulation of B cell activation GO:0050864 50 30 1,000 0,01016055 0,06571583 ! response to heat GO:0009408 50 30 1,000 0,01016055 0,06553965 ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,01029536 0,06623164 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 0,01061549 0,06810896 ! inner ear morphogenesis GO:0042472 47 31 1,000 0,01082538 0,06927091 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01082538 0,06908717 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01082538 0,0689044 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 0,01082538 0,06872259 ! triglyceride metabolic process GO:0006641 43 31 1,000 0,01082538 0,06854174 ! mesoderm formation GO:0001707 69 31 1,000 0,01082538 0,06836184 ! myeloid leukocyte activation GO:0002274 49 31 1,000 0,01082538 0,06818289 ! protein-DNA complex assembly GO:0065004 130 90 2,000 0,01094134 0,06873331 ! cholesterol transport GO:0030301 56 32 1,000 0,01150892 0,07211057 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 1,000 0,01150892 0,07192327 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01150892 0,07173694 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 0,01150892 0,07155157 ! BMP signaling pathway GO:0030509 64 32 1,000 0,01150892 0,07136716 ! hindbrain development GO:0030902 61 32 1,000 0,01150892 0,0711837 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01150892 0,07100118 ! nucleosome organization GO:0034728 138 92 2,000 0,01161028 0,0714433 ! carbohydrate biosynthetic process GO:0016051 141 93 2,000 0,0119534 0,07336706 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,0119534 0,07318037 ! post-embryonic development GO:0009791 69 33 1,000 0,01221097 0,07456748 ! formation of primary germ layer GO:0001704 72 33 1,000 0,01221097 0,0743787 ! cell fate specification GO:0001708 52 33 1,000 0,01221097 0,07419087 ! sterol transport GO:0015918 57 33 1,000 0,01221097 0,074004 ! adult locomotory behavior GO:0008344 59 33 1,000 0,01221097 0,07381806 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 0,01265703 0,07632285 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01293132 0,07778189 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,01293132 0,07758792 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,01293132 0,07739491 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 0,01293132 0,07720287 ! positive regulation of immune response GO:0050778 156 96 2,000 0,01301757 0,07752541 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,01338393 0,07951047 ! regulation of protein localization GO:0032880 176 97 2,000 0,01338393 0,07931463 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01366978 0,08080954 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,01366978 0,08061148 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01366978 0,08041438 ! interphase GO:0051325 213 98 2,000 0,01375614 0,08072507 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01442614 0,08445081 ! cell cycle arrest GO:0007050 213 100 2,000 0,01451814 0,08478312 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01599177 0,09316274 ! lipid homeostasis GO:0055088 67 38 1,000 0,01599177 0,0929377 ! nucleotide catabolic process GO:0009166 61 38 1,000 0,01599177 0,09271376 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01599177 0,09249089 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 0,01680066 0,09693619 ! ear morphogenesis GO:0042471 60 39 1,000 0,01680066 0,09670428 ! segmentation GO:0035282 67 39 1,000 0,01680066 0,09647348 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,01680066 0,09624378 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,01762667 0,10073576 ! cytokinesis GO:0000910 72 40 1,000 0,01762667 0,10049705 ! hormone-mediated signaling GO:0009755 74 41 1,000 0,0184696 0,10505402 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,0184696 0,10480625 ! T cell differentiation GO:0030217 81 41 1,000 0,0184696 0,10455964 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,0184696 0,1043142 ! polyol metabolic process GO:0019751 66 41 1,000 0,0184696 0,1040699 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01932926 0,10865936 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01932926 0,10840607 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,01932926 0,10815397 ! neuron migration GO:0001764 79 42 1,000 0,01932926 0,10790303 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02020548 0,11253327 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,02020548 0,11227338 ! glucose transport GO:0015758 65 43 1,000 0,02020548 0,11201468 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,02020548 0,11175718 ! hexose transport GO:0008645 67 44 1,000 0,02109805 0,11642637 GO:0015749|monosaccharide transport, ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,02109805 0,11615995 ! developmental growth GO:0048589 82 44 1,000 0,02109805 0,11589474 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,02200679 0,12061123 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,02200679 0,12033712 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,02200679 0,12006424 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,02200679 0,1197926 ! icosanoid metabolic process GO:0006690 80 45 1,000 0,02200679 0,11952219 ! cell growth GO:0016049 84 45 1,000 0,02200679 0,119253 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,02293152 0,12398478 ! positive regulation of defense response GO:0031349 76 47 1,000 0,02387205 0,1287806 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02387205 0,1284925 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,02387205 0,12820568 ! JNK cascade GO:0007254 91 47 1,000 0,02387205 0,12792015 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,0248282 0,13274811 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,0248282 0,13245376 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,0248282 0,13216073 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02514581 0,13355591 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02514581 0,13326174 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02514581 0,13296885 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02514581 0,13267726 ! neuron fate determination GO:0048664 7 5 0,000 0,02514581 0,13238693 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02514581 0,13209788 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02514581 0,13181008 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02514581 0,13152354 ! polyol transport GO:0015791 12 5 0,000 0,02514581 0,13123824 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02514581 0,13095417 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02514581 0,13067134 ! response to superoxide GO:0000303 10 5 0,000 0,02514581 0,13038972 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02514581 0,13010931 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02514581 0,1298301 GO:0045940|positive regulation of steroid metabolic process, ! tongue development GO:0043586 8 5 0,000 0,02514581 0,1295521 ! female meiosis GO:0007143 7 5 0,000 0,02514581 0,12927527 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02514581 0,12899963 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02514581 0,12872517 ! cobalt ion transport GO:0006824 11 5 0,000 0,02514581 0,12845187 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02514581 0,12817972 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02514581 0,12790873 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02514581 0,12763888 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02514581 0,12737017 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02514581 0,12710258 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02514581 0,12683612 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02514581 0,12657077 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02514581 0,12630653 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02514581 0,12604339 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02514581 0,12578135 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02514581 0,12552039 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02514581 0,12526051 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02514581 0,12500171 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02514581 0,12474398 ! negative chemotaxis GO:0050919 14 5 0,000 0,02514581 0,1244873 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02514581 0,12423168 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02514581 0,12397711 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02514581 0,12372358 ! behavioral response to pain GO:0048266 9 5 0,000 0,02514581 0,12347108 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02514581 0,12321961 ! Notch receptor processing GO:0007220 8 5 0,000 0,02514581 0,12296916 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02514581 0,12271973 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02514581 0,12247131 ! micturition GO:0060073 9 5 0,000 0,02514581 0,1222239 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02514581 0,12197748 ! copulation GO:0007620 9 5 0,000 0,02514581 0,12173205 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02514581 0,12148761 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02514581 0,12124415 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02514581 0,12100166 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02514581 0,12076014 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02514581 0,12051958 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02514581 0,12027998 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02514581 0,12004133 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02514581 0,11980362 ! grooming behavior GO:0007625 6 5 0,000 0,02514581 0,11956686 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02514581 0,11933102 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02514581 0,11909612 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02514581 0,11886214 ! response to protozoan GO:0001562 10 5 0,000 0,02514581 0,11862908 ! lymph vessel development GO:0001945 10 5 0,000 0,02514581 0,11839692 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02514581 0,11816568 ! endochondral ossification GO:0001958 16 5 0,000 0,02514581 0,11793534 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02514581 0,11770589 ! parathyroid gland development GO:0060017 13 5 0,000 0,02514581 0,11747734 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02514581 0,11724967 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02514581 0,11702288 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02514581 0,11679697 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02514581 0,11657192 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02514581 0,11634775 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02514581 0,11612443 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02514581 0,11590197 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02514581 0,11568036 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02514581 0,1154596 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02514581 0,11523967 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02514581 0,11502059 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02514581 0,11480233 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02514581 0,1145849 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02514581 0,1143683 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02514581 0,11415251 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02514581 0,11393753 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02514581 0,11372336 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02514581 0,11351 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02514581 0,11329743 ! histidine catabolic process GO:0006548 6 5 0,000 0,02514581 0,11308566 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02514581 0,11287468 ! valine metabolic process GO:0006573 10 5 0,000 0,02514581 0,11266449 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02514581 0,11245507 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02514581 0,11224644 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02514581 0,11203857 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02514581 0,11183148 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02514581 0,11162515 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02514581 0,11141957 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02514581 0,11121476 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02514581 0,11101069 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02514581 0,11080738 ! muscle cell migration GO:0014812 8 5 0,000 0,02514581 0,11060481 ! mitochondrial fission GO:0000266 8 5 0,000 0,02514581 0,11040297 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02514581 0,11020187 ! mRNA transcription GO:0009299 9 5 0,000 0,02514581 0,11000151 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02514581 0,10980187 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02514581 0,10960295 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02514581 0,10940475 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02514581 0,10920727 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02514581 0,1090105 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02514581 0,10881444 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02514581 0,10861908 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02514581 0,10842442 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02514581 0,10823046 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02514581 0,10803719 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02514581 0,10784461 ! forebrain neuron development GO:0021884 13 5 0,000 0,02514581 0,10765272 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02514581 0,10746151 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02514581 0,10727097 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02514581 0,10708111 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02514581 0,10689192 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02514581 0,1067034 ! folic acid transport GO:0015884 10 5 0,000 0,02514581 0,10651554 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02514581 0,10632835 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02514581 0,1061418 ! basic amino acid transport GO:0015802 11 5 0,000 0,02514581 0,10595592 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02514581 0,10577068 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02514581 0,10558609 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02514581 0,10540214 ! depyrimidination GO:0045008 10 5 0,000 0,02514581 0,10521883 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02514581 0,10503616 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02514581 0,10485412 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02514581 0,10467271 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02514581 0,10449193 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02514581 0,10431177 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02514581 0,10413224 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02514581 0,10395331 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02514581 0,10377501 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02514581 0,10359731 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02514581 0,10342022 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02514581 0,10324373 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02514581 0,10306785 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02514581 0,10289257 ! response to arsenic GO:0046685 10 5 0,000 0,02514581 0,10271788 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02514581 0,10254378 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02514581 0,10237027 GO:0002448|mast cell mediated immunity, ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02514581 0,10219735 ! response to cadmium ion GO:0046686 7 5 0,000 0,02514581 0,10202501 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02514581 0,10185325 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02514581 0,10168206 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02514581 0,10151146 ! decidualization GO:0046697 11 5 0,000 0,02514581 0,10134142 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02514581 0,10117195 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02514581 0,10100305 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02514581 0,10083471 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02514581 0,10066694 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02514581 0,10049972 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02514581 0,10033305 ! neural tube patterning GO:0021532 7 5 0,000 0,02514581 0,10016693 ! embryonic cleavage GO:0040016 6 5 0,000 0,02514581 0,10000137 ! peroxisome fission GO:0016559 5 5 0,000 0,02514581 0,09983635 ! histone demethylation GO:0016577 10 5 0,000 0,02514581 0,09967188 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02514581 0,09950794 ! mitotic recombination GO:0006312 9 5 0,000 0,02514581 0,09934455 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02514581 0,09918169 ! metaphase plate congression GO:0051310 7 5 0,000 0,02514581 0,09901936 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02514581 0,09885756 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02514581 0,09869629 ! enteric nervous system development GO:0048484 8 5 0,000 0,02514581 0,09853555 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02514581 0,09837533 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02514581 0,09821563 GO:0031295|T cell costimulation, ! muscle cell proliferation GO:0033002 11 5 0,000 0,02514581 0,09805645 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02514581 0,09789778 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02514581 0,09773963 ! plasminogen activation GO:0031639 5 5 0,000 0,02514581 0,09758198 ! B cell homeostasis GO:0001782 13 5 0,000 0,02514581 0,09742484 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02514581 0,09726821 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02514581 0,09711208 ! metaphase GO:0051323 8 5 0,000 0,02514581 0,09695646 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02514581 0,09680133 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02514581 0,09664669 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02514581 0,09649255 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02514581 0,0963389 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02514581 0,09618574 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02514581 0,09603306 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02514581 0,09588087 ! response to redox state GO:0051775 5 5 0,000 0,02514581 0,09572916 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02514581 0,09557793 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02514581 0,09542717 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02514581 0,0952769 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02514581 0,09512709 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02514581 0,09497775 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02514581 0,09482889 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02514581 0,09468048 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02514581 0,09453254 ! striatum development GO:0021756 9 5 0,000 0,02514581 0,09438507 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02514581 0,09423805 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02514581 0,09409149 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02514581 0,09394539 ! glial cell migration GO:0008347 11 5 0,000 0,02514581 0,09379973 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02514581 0,09365453 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02514581 0,09350978 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02514581 0,09336548 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02514581 0,09322162 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02514581 0,0930782 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02514581 0,09293522 ! neuroprotection GO:0043526 6 5 0,000 0,02514581 0,09279268 ! neural plate development GO:0001840 8 5 0,000 0,02514581 0,09265058 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02514581 0,09250891 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02514581 0,09236768 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02514581 0,09222687 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02514581 0,0920865 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02514581 0,09194655 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02514581 0,09180702 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02514581 0,09166792 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02514581 0,09152924 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02514581 0,09139098 ! spindle assembly GO:0051225 6 5 0,000 0,02514581 0,09125314 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02514581 0,09111571 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02514581 0,09097869 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02514581 0,09084209 ! drug metabolic process GO:0017144 6 5 0,000 0,02514581 0,09070589 ! stem cell division GO:0017145 11 5 0,000 0,02514581 0,0905701 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02514581 0,09043472 ! organ regeneration GO:0031100 7 5 0,000 0,02514581 0,09029974 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02514581 0,09016517 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02514581 0,090031 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,02579979 0,09223521 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,02579979 0,09209837 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,02579979 0,09196192 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02579979 0,09182588 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,02579979 0,09169025 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,02579979 0,09155501 GO:0019724|B cell mediated immunity, ! neuromuscular process GO:0050905 99 50 1,000 0,02678664 0,09491703 ! inner ear development GO:0048839 79 50 1,000 0,02678664 0,09477745 ! histone modification GO:0016570 91 50 1,000 0,02678664 0,09463827 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,02678664 0,09449951 ! positive regulation of binding GO:0051099 78 51 1,000 0,02778858 0,09789066 ! viral infectious cycle GO:0019058 99 51 1,000 0,02778858 0,09774755 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,02778858 0,09760485 ! vesicle organization GO:0016050 107 51 1,000 0,02778858 0,09746257 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,02778858 0,0973207 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 81 52 1,000 0,02880542 0,10073523 ! membrane fusion GO:0006944 110 52 1,000 0,02880542 0,10058903 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02880542 0,10044325 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,02983699 0,10388973 ! cell maturation GO:0048469 100 53 1,000 0,02983699 0,1037396 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03009908 0,10449983 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03009908 0,10434925 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03009908 0,10419911 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03009908 0,1040494 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03009908 0,10390012 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03009908 0,10375126 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03009908 0,10360284 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03009908 0,10345483 ! sleep GO:0030431 13 6 0,000 0,03009908 0,10330725 ! response to oxygen radical GO:0000305 11 6 0,000 0,03009908 0,10316009 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03009908 0,10301335 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03009908 0,10286702 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03009908 0,10272111 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03009908 0,10257561 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03009908 0,10243053 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03009908 0,10228585 ! forebrain regionalization GO:0021871 8 6 0,000 0,03009908 0,10214158 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03009908 0,10199772 ! male meiosis GO:0007140 7 6 0,000 0,03009908 0,10185426 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03009908 0,10171121 ! response to zinc ion GO:0010043 9 6 0,000 0,03009908 0,10156856 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03009908 0,10142631 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03009908 0,10128445 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03009908 0,10114299 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03009908 0,10100193 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03009908 0,10086126 ! malate metabolic process GO:0006108 11 6 0,000 0,03009908 0,10072098 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03009908 0,10058109 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03009908 0,10044158 ! protein refolding GO:0042026 15 6 0,000 0,03009908 0,10030247 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03009908 0,10016374 ! opsonization GO:0008228 8 6 0,000 0,03009908 0,10002539 ! mating behavior GO:0007617 7 6 0,000 0,03009908 0,09988742 ! neuron remodeling GO:0016322 15 6 0,000 0,03009908 0,09974984 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03009908 0,09961263 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03009908 0,0994758 ! equilibrioception GO:0050957 14 6 0,000 0,03009908 0,09933934 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03009908 0,09920326 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03009908 0,09906755 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03009908 0,09893222 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03009908 0,09879725 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03009908 0,09866265 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03009908 0,09852841 ! toxin metabolic process GO:0009404 11 6 0,000 0,03009908 0,09839454 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03009908 0,09826103 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03009908 0,09812789 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03009908 0,0979951 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03009908 0,09786268 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03009908 0,09773061 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03009908 0,0975989 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03009908 0,09746754 ! thymic T cell selection GO:0045061 12 6 0,000 0,03009908 0,09733654 ! protein lipoylation GO:0009249 10 6 0,000 0,03009908 0,09720588 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03009908 0,09707558 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03009908 0,09694563 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03009908 0,09681602 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03009908 0,09668676 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03009908 0,09655784 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,03009908 0,09642927 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03009908 0,09630104 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03009908 0,09617315 ! hyperosmotic response GO:0006972 9 6 0,000 0,03009908 0,0960456 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03009908 0,09591839 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03009908 0,09579151 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03009908 0,09566497 ! urea metabolic process GO:0019627 7 6 0,000 0,03009908 0,09553876 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03009908 0,09541289 ! neutrophil activation GO:0042119 8 6 0,000 0,03009908 0,09528735 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03009908 0,09516213 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03009908 0,09503725 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03009908 0,09491269 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03009908 0,09478846 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03009908 0,09466455 ! neuron apoptosis GO:0051402 9 6 0,000 0,03009908 0,09454097 ! nucleoside salvage GO:0043174 9 6 0,000 0,03009908 0,09441771 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03009908 0,09429477 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03009908 0,09417215 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03009908 0,09404985 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03009908 0,09392786 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03009908 0,09380619 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03009908 0,09368484 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03009908 0,0935638 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03009908 0,09344307 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03009908 0,09332266 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03009908 0,09320255 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03009908 0,09308275 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03009908 0,09296326 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03009908 0,09284408 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03009908 0,0927252 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03009908 0,09260663 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03009908 0,09248836 ! neural nucleus development GO:0048857 14 6 0,000 0,03009908 0,09237039 ! response to UV-C GO:0010225 11 6 0,000 0,03009908 0,09225272 ! astrocyte development GO:0014002 15 6 0,000 0,03009908 0,09213535 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03009908 0,09201827 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03009908 0,0919015 ! interaction with symbiont GO:0051702 13 6 0,000 0,03009908 0,09178502 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03009908 0,09166884 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03009908 0,09155295 ! response to copper ion GO:0046688 10 6 0,000 0,03009908 0,09143735 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03009908 0,09132205 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03009908 0,09120703 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03009908 0,0910923 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03009908 0,09097787 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03009908 0,09086372 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03009908 0,09074985 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03009908 0,09063627 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03009908 0,09052298 ! Schwann cell development GO:0014044 15 6 0,000 0,03009908 0,09040997 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03009908 0,09029723 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03009908 0,09018478 ! subpallium development GO:0021544 10 6 0,000 0,03009908 0,09007261 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03009908 0,08996072 ! histone ubiquitination GO:0016574 8 6 0,000 0,03009908 0,08984911 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03009908 0,08973777 ! G2 phase GO:0051319 16 6 0,000 0,03009908 0,08962671 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03009908 0,08951592 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03009908 0,08940541 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03009908 0,08929517 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03009908 0,0891852 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03009908 0,0890755 ! receptor internalization GO:0031623 10 6 0,000 0,03009908 0,08896607 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03009908 0,08885691 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03009908 0,08874802 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03009908 0,08863939 ! protein deubiquitination GO:0016579 14 6 0,000 0,03009908 0,08853103 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03009908 0,08842293 ! protein destabilization GO:0031648 9 6 0,000 0,03009908 0,0883151 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03009908 0,08820753 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03009908 0,08810022 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03009908 0,08799317 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03009908 0,08788639 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03009908 0,08777986 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03009908 0,08767359 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03009908 0,08756757 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03009908 0,08746181 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03009908 0,08735631 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03009908 0,08725106 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03009908 0,08714607 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03009908 0,08704132 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03009908 0,08693683 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03009908 0,08683259 ! catecholamine transport GO:0051937 9 6 0,000 0,03009908 0,0867286 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03009908 0,08662486 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03009908 0,08652136 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03009908 0,08641812 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03009908 0,08631512 ! maternal placenta development GO:0001893 12 6 0,000 0,03009908 0,08621236 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03009908 0,08610985 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03009908 0,08600758 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03009908 0,08590555 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03009908 0,08580377 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03009908 0,08570223 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03009908 0,08560092 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03088312 0,08772702 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,03088312 0,08762357 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,03088312 0,08752037 ! glutamine family amino acid metabolic process GO:0009064 78 54 1,000 0,03088312 0,0874174 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,03088312 0,08731468 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,03194364 0,09020703 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,03194364 0,09010127 ! gastrulation GO:0007369 112 55 1,000 0,03194364 0,08999577 ! heart morphogenesis GO:0003007 97 55 1,000 0,03194364 0,08989051 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,03194364 0,0897855 ! RNA elongation GO:0006354 79 55 1,000 0,03194364 0,08968073 ! regulation of actin filament length GO:0030832 105 56 1,000 0,03301836 0,09258995 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,03301836 0,09248217 ! lipid modification GO:0030258 97 57 1,000 0,03410713 0,09542066 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,03410713 0,09530983 ! maintenance of location GO:0051235 118 57 1,000 0,03410713 0,09519926 ! tRNA transcription GO:0009304 14 7 0,000 0,03502734 0,09765443 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03502734 0,09754141 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03502734 0,09742864 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03502734 0,09731614 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03502734 0,09720389 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03502734 0,09709191 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03502734 0,09698018 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03502734 0,09686871 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03502734 0,09675749 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03502734 0,09664653 ! prostate gland development GO:0030850 13 7 0,000 0,03502734 0,09653583 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03502734 0,09642537 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03502734 0,09631517 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03502734 0,09620522 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03502734 0,09609553 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03502734 0,09598608 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03502734 0,09587688 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03502734 0,09576793 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03502734 0,09565922 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03502734 0,09555077 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03502734 0,09544256 ! glycolipid transport GO:0046836 10 7 0,000 0,03502734 0,09533459 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03502734 0,09522687 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03502734 0,09511939 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03502734 0,09501215 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03502734 0,09490515 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03502734 0,0947984 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03502734 0,09469188 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03502734 0,09458561 ! mRNA stabilization GO:0048255 18 7 0,000 0,03502734 0,09447957 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03502734 0,09437377 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03502734 0,09426821 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03502734 0,09416288 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03502734 0,09405779 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03502734 0,09395293 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03502734 0,0938483 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03502734 0,09374391 ! lipoprotein transport GO:0042953 14 7 0,000 0,03502734 0,09363975 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03502734 0,09353582 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03502734 0,09343212 ! rhythmic behavior GO:0007622 15 7 0,000 0,03502734 0,09332866 ! estrogen metabolic process GO:0008210 17 7 0,000 0,03502734 0,09322542 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03502734 0,0931224 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03502734 0,09301962 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03502734 0,09291706 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03502734 0,09281473 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03502734 0,09271262 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03502734 0,09261074 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03502734 0,09250908 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03502734 0,09240765 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03502734 0,09230644 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03502734 0,09220544 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03502734 0,09210467 ! spinal cord patterning GO:0021511 13 7 0,000 0,03502734 0,09200412 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03502734 0,09190379 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03502734 0,09180368 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03502734 0,09170378 ! adrenal gland development GO:0030325 17 7 0,000 0,03502734 0,0916041 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03502734 0,09150464 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03502734 0,0914054 ! ovulation GO:0030728 9 7 0,000 0,03502734 0,09130637 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03502734 0,09120755 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03502734 0,09110895 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03502734 0,09101056 ! microtubule nucleation GO:0007020 20 7 0,000 0,03502734 0,09091238 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03502734 0,09081441 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03502734 0,09071666 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03502734 0,09061911 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03502734 0,09052178 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03502734 0,09042465 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03502734 0,09032773 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03502734 0,09023102 ! galactose metabolic process GO:0006012 13 7 0,000 0,03502734 0,09013452 ! response to dietary excess GO:0002021 8 7 0,000 0,03502734 0,09003822 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03502734 0,08994213 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03502734 0,08984624 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03502734 0,08975056 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03502734 0,08965508 ! organ growth GO:0035265 15 7 0,000 0,03502734 0,0895598 ! purine salvage GO:0043101 10 7 0,000 0,03502734 0,08946473 ! nucleoside transport GO:0015858 8 7 0,000 0,03502734 0,08936986 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03502734 0,08927519 ! parturition GO:0007567 14 7 0,000 0,03502734 0,08918072 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03502734 0,08908644 ! rRNA modification GO:0000154 14 7 0,000 0,03502734 0,08899237 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03502734 0,0888985 ! spindle checkpoint GO:0031577 15 7 0,000 0,03502734 0,08880482 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03502734 0,08871134 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03502734 0,08861806 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03502734 0,08852497 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03502734 0,08843208 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03502734 0,08833939 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03502734 0,08824689 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03502734 0,08815458 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03502734 0,08806246 ! fibrinolysis GO:0042730 10 7 0,000 0,03502734 0,08797054 ! eating behavior GO:0042755 7 7 0,000 0,03502734 0,08787881 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03502734 0,08778727 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03502734 0,08769592 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03502734 0,08760476 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03502734 0,08751379 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03502734 0,087423 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03502734 0,08733241 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03502734 0,087242 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03502734 0,08715179 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03502734 0,08706175 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03502734 0,08697191 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03502734 0,08688224 ! regulation of meiosis GO:0040020 12 7 0,000 0,03502734 0,08679277 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03502734 0,08670347 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03502734 0,08661436 ! regulation of lipid transport GO:0032368 14 7 0,000 0,03502734 0,08652544 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03502734 0,08643669 ! transcription termination GO:0006353 13 7 0,000 0,03502734 0,08634813 ! response to tumor cell GO:0002347 13 7 0,000 0,03502734 0,08625975 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03502734 0,08617155 ! anaphase GO:0051322 17 7 0,000 0,03502734 0,08608353 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03502734 0,08599569 ! axonal fasciculation GO:0007413 18 7 0,000 0,03502734 0,08590803 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03502734 0,08582055 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03502734 0,08573324 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03502734 0,08564611 ! diuresis GO:0030146 12 7 0,000 0,03502734 0,08555916 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03502734 0,08547239 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03502734 0,08538579 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03502734 0,08529937 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03502734 0,08521312 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03502734 0,08512705 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03502734 0,08504115 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03502734 0,08495542 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03502734 0,08486987 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03502734 0,08478448 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03502734 0,08469927 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03502734 0,08461423 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03502734 0,08452936 ! lymph node development GO:0048535 10 7 0,000 0,03502734 0,08444467 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03502734 0,08436014 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03502734 0,08427578 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03502734 0,08419158 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03502734 0,08410756 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03502734 0,08402371 ! adult feeding behavior GO:0008343 9 7 0,000 0,03502734 0,08394002 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03502734 0,08385649 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03502734 0,08377314 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03502734 0,08368995 ! muscle adaptation GO:0043500 14 7 0,000 0,03502734 0,08360692 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03502734 0,08352406 ! retina homeostasis GO:0001895 12 7 0,000 0,03502734 0,08344136 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03502734 0,08335883 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03502734 0,08327646 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03502734 0,08319425 ! protein prenylation GO:0018342 18 7 0,000 0,03502734 0,08311221 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03502734 0,08303032 ! regulation of endocytosis GO:0030100 91 58 1,000 0,03520978 0,08338064 ! adult behavior GO:0030534 99 58 1,000 0,03520978 0,08329865 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,03520978 0,08321683 ! regulation of cellular component size GO:0032535 109 59 1,000 0,03632614 0,08577103 ! DNA catabolic process GO:0006308 86 59 1,000 0,03632614 0,08568694 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,03632614 0,08560302 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,03745603 0,08817927 ! ear development GO:0043583 103 62 1,000 0,0397558 0,09350191 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,0397558 0,0934106 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03993072 0,09373006 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03993072 0,09363871 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03993072 0,09354753 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03993072 0,09345653 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03993072 0,09336571 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03993072 0,09327506 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03993072 0,09318459 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03993072 0,09309429 ! meiotic prophase I GO:0007128 13 8 0,000 0,03993072 0,09300417 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03993072 0,09291423 ! oligopeptide transport GO:0006857 15 8 0,000 0,03993072 0,09282446 ! UTP metabolic process GO:0046051 8 8 0,000 0,03993072 0,09273486 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03993072 0,09264543 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03993072 0,09255618 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03993072 0,0924671 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03993072 0,09237818 ! succinate metabolic process GO:0006105 14 8 0,000 0,03993072 0,09228944 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03993072 0,09220088 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03993072 0,09211248 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03993072 0,09202425 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03993072 0,09193618 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03993072 0,09184829 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03993072 0,09176057 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03993072 0,09167301 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03993072 0,09158562 ! reflex GO:0060004 16 8 0,000 0,03993072 0,09149839 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03993072 0,09141133 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03993072 0,09132444 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03993072 0,09123771 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03993072 0,09115115 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03993072 0,09106475 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03993072 0,09097852 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03993072 0,09089244 ! pigment granule organization GO:0048753 16 8 0,000 0,03993072 0,09080653 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03993072 0,09072079 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03993072 0,0906352 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03993072 0,09054978 ! histidine metabolic process GO:0006547 16 8 0,000 0,03993072 0,09046451 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03993072 0,09037941 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03993072 0,09029447 ! glycine catabolic process GO:0006546 13 8 0,000 0,03993072 0,09020968 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03993072 0,09012506 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03993072 0,09004059 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03993072 0,08995628 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03993072 0,08987213 ! melanin metabolic process GO:0006582 15 8 0,000 0,03993072 0,08978814 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03993072 0,08970431 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03993072 0,08962063 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03993072 0,0895371 ! macrophage activation GO:0042116 12 8 0,000 0,03993072 0,08945374 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03993072 0,08937052 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03993072 0,08928746 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03993072 0,08920456 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03993072 0,08912181 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03993072 0,08903921 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03993072 0,08895677 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03993072 0,08887448 ! osteoblast development GO:0002076 16 8 0,000 0,03993072 0,08879234 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03993072 0,08871035 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03993072 0,08862852 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03993072 0,08854683 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03993072 0,0884653 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03993072 0,08838391 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03993072 0,08830268 ! response to UV-B GO:0010224 16 8 0,000 0,03993072 0,08822159 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03993072 0,08814065 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03993072 0,08805986 ! intermediate filament organization GO:0045109 12 8 0,000 0,03993072 0,08797922 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03993072 0,08789873 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03993072 0,08781838 ! cellular extravasation GO:0045123 12 8 0,000 0,03993072 0,08773818 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03993072 0,08765813 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03993072 0,08757822 ! response to antibiotic GO:0046677 11 8 0,000 0,03993072 0,08749846 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03993072 0,08741885 ! DNA topological change GO:0006265 12 8 0,000 0,03993072 0,08733937 ! response to tropane GO:0014073 15 8 0,000 0,03993072 0,08726005 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,03993072 0,08718086 ! melanosome transport GO:0032402 13 8 0,000 0,03993072 0,08710182 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03993072 0,08702293 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03993072 0,08694417 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03993072 0,08686556 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03993072 0,08678709 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03993072 0,08670877 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03993072 0,08663058 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03993072 0,08655253 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03993072 0,08647463 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03993072 0,08639686 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03993072 0,08631924 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03993072 0,08624175 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03993072 0,08616441 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03993072 0,0860872 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03993072 0,08601013 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03993072 0,0859332 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03993072 0,0858564 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03993072 0,08577974 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03993072 0,08570322 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03993072 0,08562684 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03993072 0,08555059 ! hormone catabolic process GO:0042447 17 8 0,000 0,03993072 0,08547448 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03993072 0,0853985 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03993072 0,08532266 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03993072 0,08524695 ! ATP catabolic process GO:0006200 11 8 0,000 0,03993072 0,08517138 ! blastocyst growth GO:0001832 19 8 0,000 0,03993072 0,08509594 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03993072 0,08502063 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03993072 0,08494546 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03993072 0,08487042 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03993072 0,08479551 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03993072 0,08472073 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03993072 0,08464609 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03993072 0,08457158 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03993072 0,0844972 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03993072 0,08442295 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03993072 0,08434883 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03993072 0,08427484 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03993072 0,08420097 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03993072 0,08412724 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03993072 0,08405364 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03993072 0,08398017 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03993072 0,08390682 ! cell redox homeostasis GO:0045454 102 64 1,000 0,04210778 0,0884043 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,04210778 0,08832722 ! single fertilization GO:0007338 75 64 1,000 0,04210778 0,08825028 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,04330295 0,09067616 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,04330295 0,09059731 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,04330295 0,0905186 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,0445107 0,09296245 ! fatty acid biosynthetic process GO:0006633 124 66 1,000 0,0445107 0,09288182 ! axon extension GO:0048675 15 9 0,000 0,04480935 0,09342399 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04480935 0,09334311 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04480935 0,09326236 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04480935 0,09318175 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04480935 0,09310129 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04480935 0,09302096 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04480935 0,09294077 ! phosphate transport GO:0006817 19 9 0,000 0,04480935 0,09286072 ! reproductive behavior GO:0019098 19 9 0,000 0,04480935 0,0927808 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04480935 0,09270102 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04480935 0,09262138 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04480935 0,09254188 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04480935 0,09246251 ! GTP metabolic process GO:0046039 9 9 0,000 0,04480935 0,09238328 ! RNA methylation GO:0001510 15 9 0,000 0,04480935 0,09230419 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04480935 0,09222523 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,04480935 0,0921464 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04480935 0,09206771 ! artery development GO:0060840 24 9 0,000 0,04480935 0,09198916 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04480935 0,09191073 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04480935 0,09183244 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04480935 0,09175429 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04480935 0,09167627 ! chemosensory behavior GO:0007635 20 9 0,000 0,04480935 0,09159838 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04480935 0,09152062 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04480935 0,09144299 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04480935 0,0913655 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04480935 0,09128814 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04480935 0,09121091 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04480935 0,0911338 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04480935 0,09105683 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04480935 0,09097999 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04480935 0,09090328 ! protein targeting to ER GO:0045047 22 9 0,000 0,04480935 0,0908267 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04480935 0,09075024 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04480935 0,09067392 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04480935 0,09059772 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04480935 0,09052165 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04480935 0,09044571 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04480935 0,0903699 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04480935 0,09029421 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04480935 0,09021865 ! mannose metabolic process GO:0006013 13 9 0,000 0,04480935 0,09014322 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04480935 0,09006791 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04480935 0,08999273 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04480935 0,08991767 ! receptor clustering GO:0043113 18 9 0,000 0,04480935 0,08984274 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04480935 0,08976794 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04480935 0,08969325 ! ruffle organization GO:0031529 15 9 0,000 0,04480935 0,0896187 ! retinol metabolic process GO:0042572 18 9 0,000 0,04480935 0,08954426 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04480935 0,08946995 ! behavioral fear response GO:0001662 22 9 0,000 0,04480935 0,08939576 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04480935 0,0893217 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04480935 0,08924776 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04480935 0,08917394 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,04480935 0,08910024 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04480935 0,08902666 ! segment specification GO:0007379 13 9 0,000 0,04480935 0,08895321 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04480935 0,08887988 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04480935 0,08880666 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04480935 0,08873357 ! response to amine stimulus GO:0014075 13 9 0,000 0,04480935 0,0886606 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04480935 0,08858775 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04480935 0,08851502 ! erythrocyte development GO:0048821 15 9 0,000 0,04480935 0,0884424 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04480935 0,08836991 ! renal water homeostasis GO:0003091 14 9 0,000 0,04480935 0,08829753 ! postreplication repair GO:0006301 22 9 0,000 0,04480935 0,08822528 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04480935 0,08815314 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04480935 0,08808112 ! icosanoid secretion GO:0032309 15 9 0,000 0,04480935 0,08800922 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04480935 0,08793743 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04480935 0,08786576 ! regulation of cell division GO:0051302 15 9 0,000 0,04480935 0,08779421 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04480935 0,08772277 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04480935 0,08765146 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04480935 0,08758025 ! sterol catabolic process GO:0016127 11 9 0,000 0,04480935 0,08750916 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04480935 0,08743819 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04480935 0,08736733 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04480935 0,08729659 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04480935 0,08722596 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04480935 0,08715545 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04480935 0,08708505 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04480935 0,08701476 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04480935 0,08694459 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04480935 0,08687453 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04480935 0,08680458 ! purine base metabolic process GO:0006144 21 9 0,000 0,04480935 0,08673475 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04480935 0,08666502 ! pigment granule transport GO:0051904 17 9 0,000 0,04480935 0,08659541 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04480935 0,08652592 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04480935 0,08645653 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04480935 0,08638725 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04480935 0,08631809 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04480935 0,08624903 ! mitochondrion localization GO:0051646 15 9 0,000 0,04480935 0,08618009 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,04573086 0,08788215 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,04573086 0,08781202 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,04573086 0,08774199 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,04573086 0,08767208 ! adaptive immune response GO:0002250 119 67 1,000 0,04573086 0,08760227 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,04696329 0,08989155 ! regulation of lipase activity GO:0060191 130 68 1,000 0,04696329 0,08982009 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,04820783 0,09212711 ! antigen processing and presentation GO:0019882 104 69 1,000 0,04820783 0,092054 ! appendage morphogenesis GO:0035107 135 70 1,000 0,04946432 0,09437839 GO:0035108|limb morphogenesis, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04966335 0,09468305 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,04966335 0,09460808 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04966335 0,09453324 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04966335 0,09445851 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,04966335 0,09438389 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04966335 0,0943094 ! synapsis GO:0007129 13 10 0,000 0,04966335 0,09423502 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04966335 0,09416076 ! N-glycan processing GO:0006491 20 10 0,000 0,04966335 0,09408662 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04966335 0,0940126 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04966335 0,09393869 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04966335 0,09386489 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04966335 0,09379122 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04966335 0,09371765 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04966335 0,09364421 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04966335 0,09357088 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04966335 0,09349766 ! androgen metabolic process GO:0008209 17 10 0,000 0,04966335 0,09342456 ! phospholipid efflux GO:0033700 16 10 0,000 0,04966335 0,09335157 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04966335 0,0932787 ! lung alveolus development GO:0048286 26 10 0,000 0,04966335 0,09320594 ! pathogenesis GO:0009405 13 10 0,000 0,04966335 0,09313329 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04966335 0,09306075 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04966335 0,09298833 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04966335 0,09291603 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04966335 0,09284383 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04966335 0,09277175 ! endoderm development GO:0007492 16 10 0,000 0,04966335 0,09269977 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04966335 0,09262791 ! arginine catabolic process GO:0006527 13 10 0,000 0,04966335 0,09255617 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04966335 0,09248453 ! proline metabolic process GO:0006560 13 10 0,000 0,04966335 0,092413 ! L-serine metabolic process GO:0006563 18 10 0,000 0,04966335 0,09234158 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04966335 0,09227028 ! V(D)J recombination GO:0033151 28 10 0,000 0,04966335 0,09219908 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04966335 0,09212799 ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04966335 0,09205702 ! B cell proliferation GO:0042100 18 10 0,000 0,04966335 0,09198615 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04966335 0,09191539 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04966335 0,09184474 ! multicellular organism growth GO:0035264 18 10 0,000 0,04966335 0,0917742 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04966335 0,09170377 ! epithelial cell development GO:0002064 20 10 0,000 0,04966335 0,09163344 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04966335 0,09156323 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04966335 0,09149312 ! macroautophagy GO:0016236 17 10 0,000 0,04966335 0,09142311 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04966335 0,09135322 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04966335 0,09128343 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04966335 0,09121375 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04966335 0,09114417 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04966335 0,0910747 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04966335 0,09100534 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04966335 0,09093608 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04966335 0,09086693 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04966335 0,09079788 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04966335 0,09072894 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04966335 0,0906601 ! response to dsRNA GO:0043331 20 10 0,000 0,04966335 0,09059136 ! DNA ligation GO:0006266 19 10 0,000 0,04966335 0,09052273 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04966335 0,09045421 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04966335 0,09038579 ! melanosome localization GO:0032400 16 10 0,000 0,04966335 0,09031747 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04966335 0,09024925 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04966335 0,09018114 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04966335 0,09011313 ! mRNA cleavage GO:0006379 17 10 0,000 0,04966335 0,09004522 ! protein sumoylation GO:0016925 15 10 0,000 0,04966335 0,08997742 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04966335 0,08990971 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04966335 0,08984211 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04966335 0,08977461 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04966335 0,08970721 ! salivary gland development GO:0007431 27 10 0,000 0,04966335 0,08963992 ! prophase GO:0051324 15 10 0,000 0,04966335 0,08957272 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04966335 0,08950562 ! apical protein localization GO:0045176 15 10 0,000 0,04966335 0,08943863 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04966335 0,08937173 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04966335 0,08930494 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04966335 0,08923824 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04966335 0,08917165 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04966335 0,08910515 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04966335 0,08903875 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04966335 0,08897246 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04966335 0,08890626 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04966335 0,08884016 ! detection of calcium ion GO:0005513 23 10 0,000 0,04966335 0,08877415 ! oocyte development GO:0048599 17 10 0,000 0,04966335 0,08870825 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04966335 0,08864244 ! blastocyst formation GO:0001825 17 10 0,000 0,04966335 0,08857673 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04966335 0,08851112 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04966335 0,0884456 ! activation of innate immune response GO:0002218 12 10 0,000 0,04966335 0,08838018 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04966335 0,08831486 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04966335 0,08824964 ! response to nicotine GO:0035094 20 10 0,000 0,04966335 0,08818451 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04966335 0,08811948 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04966335 0,08805454 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04966335 0,0879897 ! appendage development GO:0048736 136 71 1,000 0,05073262 0,08981801 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 122 72 1,000 0,05201257 0,09201635 ! carbohydrate transport GO:0008643 110 72 1,000 0,05201257 0,09194874 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,05201257 0,09188123 ! fertilization GO:0009566 90 73 1,000 0,05330402 0,09409353 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05449284 0,09612153 ! respiratory burst GO:0045730 17 11 0,000 0,05449284 0,09605111 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05449284 0,0959808 ! neuron fate specification GO:0048665 17 11 0,000 0,05449284 0,09591058 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05449284 0,09584047 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05449284 0,09577046 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05449284 0,09570056 ! thyroid gland development GO:0030878 26 11 0,000 0,05449284 0,09563076 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05449284 0,09556105 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05449284 0,09549145 ! response to pain GO:0048265 24 11 0,000 0,05449284 0,09542196 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05449284 0,09535256 ! T cell proliferation GO:0042098 26 11 0,000 0,05449284 0,09528326 ! blood vessel remodeling GO:0001974 29 11 0,000 0,05449284 0,09521406 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,05449284 0,09514497 ! bone resorption GO:0045453 16 11 0,000 0,05449284 0,09507597 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05449284 0,09500708 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05449284 0,09493828 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05449284 0,09486958 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05449284 0,09480099 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05449284 0,09473249 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05449284 0,09466409 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05449284 0,09459579 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05449284 0,09452759 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05449284 0,09445949 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05449284 0,09439148 ! lipid digestion GO:0044241 18 11 0,000 0,05449284 0,09432357 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05449284 0,09425576 ! UV protection GO:0009650 19 11 0,000 0,05449284 0,09418805 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,05449284 0,09412044 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05449284 0,09405292 ! temperature homeostasis GO:0001659 17 11 0,000 0,05449284 0,0939855 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05449284 0,09391817 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05449284 0,09385094 ! regulation of organ growth GO:0046620 13 11 0,000 0,05449284 0,09378381 ! pigment granule localization GO:0051875 20 11 0,000 0,05449284 0,09371677 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05449284 0,09364983 ! vasoconstriction GO:0042310 18 11 0,000 0,05449284 0,09358299 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05449284 0,09351624 ! embryonic axis specification GO:0000578 18 11 0,000 0,05449284 0,09344958 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05449284 0,09338302 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05449284 0,09331656 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05449284 0,09325019 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05449284 0,09318391 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05449284 0,09311773 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05449284 0,09305164 ! zymogen activation GO:0031638 15 11 0,000 0,05449284 0,09298565 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05449284 0,09291975 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05449284 0,09285394 ! nucleosome positioning GO:0016584 15 11 0,000 0,05449284 0,09278823 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05449284 0,09272261 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05449284 0,09265708 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05449284 0,09259164 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,05449284 0,0925263 ! acid secretion GO:0046717 18 11 0,000 0,05449284 0,09246105 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05449284 0,09239589 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05449284 0,09233082 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05449284 0,09226585 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05449284 0,09220096 ! oocyte differentiation GO:0009994 18 11 0,000 0,05449284 0,09213617 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05449284 0,09207147 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,05449284 0,09200685 ! cholesterol efflux GO:0033344 19 11 0,000 0,05449284 0,09194233 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05449284 0,0918779 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05449284 0,09181356 ! germ cell migration GO:0008354 25 11 0,000 0,05449284 0,09174931 ! embryonic gut development GO:0048566 15 11 0,000 0,05449284 0,09168515 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05449284 0,09162108 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05449284 0,0915571 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05449284 0,09149321 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05449284 0,0914294 ! defense response to fungus GO:0050832 13 11 0,000 0,05449284 0,09136569 ! lysogeny GO:0030069 21 11 0,000 0,05449284 0,09130207 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05449284 0,09123853 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05449284 0,09117508 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05449284 0,09111172 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05449284 0,09104845 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05449284 0,09098526 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,05460683 0,09111237 GO:0090046|regulation of transcription regulator activity, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,05460683 0,09104923 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,05460683 0,09098618 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,05460683 0,09092321 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,05592085 0,09304673 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,05858193 0,09740714 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,05858193 0,09733987 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05929795 0,0984616 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05929795 0,09839369 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05929795 0,09832588 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05929795 0,09825817 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,05929795 0,09819054 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05929795 0,09812301 ! cartilage condensation GO:0001502 20 12 0,000 0,05929795 0,09805557 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05929795 0,09798823 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05929795 0,09792097 ! protein complex disassembly GO:0043241 27 12 0,000 0,05929795 0,09785381 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05929795 0,09778674 ! hippocampus development GO:0021766 26 12 0,000 0,05929795 0,09771977 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05929795 0,09765288 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05929795 0,09758609 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05929795 0,09751938 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05929795 0,09745277 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05929795 0,09738625 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05929795 0,09731982 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05929795 0,09725348 ! drug transport GO:0015893 16 12 0,000 0,05929795 0,09718723 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05929795 0,09712107 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05929795 0,097055 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05929795 0,09698903 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05929795 0,09692314 ! focal adhesion formation GO:0048041 35 12 0,000 0,05929795 0,09685734 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05929795 0,09679163 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05929795 0,096726 ! forebrain cell migration GO:0021885 21 12 0,000 0,05929795 0,09666047 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05929795 0,09659503 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05929795 0,09652967 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05929795 0,09646441 ! fear response GO:0042596 26 12 0,000 0,05929795 0,09639923 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05929795 0,09633414 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05929795 0,09626913 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05929795 0,09620422 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05929795 0,09613939 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05929795 0,09607465 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05929795 0,09601 ! protein homotetramerization GO:0051289 21 12 0,000 0,05929795 0,09594543 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05929795 0,09588095 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05929795 0,09581656 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05929795 0,09575225 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05929795 0,09568803 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05929795 0,0956239 ! cranial nerve development GO:0021545 20 12 0,000 0,05929795 0,09555985 ! fucose catabolic process GO:0019317 22 12 0,000 0,05929795 0,09549589 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05929795 0,09543201 ! histone methylation GO:0016571 26 12 0,000 0,05929795 0,09536822 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05929795 0,09530451 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05929795 0,09524089 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05929795 0,09517736 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05929795 0,0951139 ! spleen development GO:0048536 22 12 0,000 0,05929795 0,09505054 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05929795 0,09498726 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05929795 0,09492406 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05929795 0,09486094 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05929795 0,09479791 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05929795 0,09473497 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,05929795 0,0946721 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05929795 0,09460932 ! response to cold GO:0009409 17 12 0,000 0,05929795 0,09454663 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05929795 0,09448401 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05929795 0,09442148 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,05992871 0,09536275 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,05992871 0,09529972 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,06128612 0,09739392 ! protein import into nucleus GO:0006606 158 80 1,000 0,06265402 0,09950202 ! inorganic anion transport GO:0015698 138 80 1,000 0,06265402 0,09943639 ! T cell activation GO:0042110 168 81 1,000 0,06403227 0,10155678 ! nuclear import GO:0051170 161 81 1,000 0,06403227 0,10148988 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06407879 0,10149676 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06407879 0,10142998 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06407879 0,1013633 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06407879 0,1012967 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06407879 0,10123019 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06407879 0,10116376 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06407879 0,10109743 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06407879 0,10103118 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06407879 0,10096501 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06407879 0,10089894 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06407879 0,10083295 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06407879 0,10076704 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06407879 0,10070123 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06407879 0,10063549 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06407879 0,10056985 ! methionine metabolic process GO:0006555 27 13 0,000 0,06407879 0,10050429 ! plasma membrane organization GO:0007009 24 13 0,000 0,06407879 0,10043881 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06407879 0,10037342 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06407879 0,10030812 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06407879 0,1002429 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06407879 0,10017776 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06407879 0,10011271 ! response to X-ray GO:0010165 25 13 0,000 0,06407879 0,10004775 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06407879 0,09998286 ! exocrine system development GO:0035272 32 13 0,000 0,06407879 0,09991807 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06407879 0,09985335 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06407879 0,09978872 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06407879 0,09972418 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06407879 0,09965971 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06407879 0,09959533 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06407879 0,09953104 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06407879 0,09946682 ! regulation of cellular pH GO:0030641 22 13 0,000 0,06407879 0,09940269 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06407879 0,09933864 ! ribosome assembly GO:0042255 17 13 0,000 0,06407879 0,09927468 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06407879 0,0992108 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06407879 0,09914699 ! chromatin silencing GO:0006342 26 13 0,000 0,06407879 0,09908328 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06407879 0,09901964 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06407879 0,09895608 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06407879 0,09889261 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06407879 0,09882922 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,06407879 0,0987659 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06407879 0,09870267 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06407879 0,09863952 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06407879 0,09857646 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06407879 0,09851347 ! embryonic placenta development GO:0001892 23 13 0,000 0,06407879 0,09845056 ! insulin secretion GO:0030073 23 13 0,000 0,06407879 0,09838773 ! actin filament polymerization GO:0030041 24 13 0,000 0,06407879 0,09832498 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06407879 0,09826232 ! acrosome reaction GO:0007340 18 13 0,000 0,06407879 0,09819973 ! negative regulation of transport GO:0051051 153 84 1,000 0,06822775 0,10449138 ! negative regulation of growth GO:0045926 155 84 1,000 0,06822775 0,10442491 ! rRNA transcription GO:0009303 25 14 0,000 0,0688355 0,10528812 ! lactation GO:0007595 26 14 0,000 0,0688355 0,10522123 ! reproductive cellular process GO:0048610 20 14 0,000 0,0688355 0,10515442 ! tRNA modification GO:0006400 20 14 0,000 0,0688355 0,1050877 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0688355 0,10502106 ! regulation of S phase GO:0033261 23 14 0,000 0,0688355 0,10495451 ! water transport GO:0006833 21 14 0,000 0,0688355 0,10488804 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0688355 0,10482166 ! non-recombinational repair GO:0000726 25 14 0,000 0,0688355 0,10475536 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0688355 0,10468914 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0688355 0,104623 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0688355 0,10455695 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0688355 0,10449099 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0688355 0,1044251 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0688355 0,1043593 ! palate development GO:0060021 31 14 0,000 0,0688355 0,10429359 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0688355 0,10422795 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0688355 0,1041624 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0688355 0,10409693 ! arginine metabolic process GO:0006525 17 14 0,000 0,0688355 0,10403154 ! regulation of heart rate GO:0002027 24 14 0,000 0,0688355 0,10396624 ! organic alcohol transport GO:0015850 29 14 0,000 0,0688355 0,10390101 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0688355 0,10383587 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0688355 0,10377081 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0688355 0,10370583 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0688355 0,10364094 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0688355 0,10357612 ! L-amino acid transport GO:0015807 30 14 0,000 0,0688355 0,10351139 ! bone mineralization GO:0030282 17 14 0,000 0,0688355 0,10344673 ! stem cell development GO:0048864 43 14 0,000 0,0688355 0,10338216 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0688355 0,10331766 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0688355 0,10325325 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0688355 0,10318892 ! cerebellum development GO:0021549 21 14 0,000 0,0688355 0,10312467 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0688355 0,1030605 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0688355 0,1029964 ! response to gamma radiation GO:0010332 28 14 0,000 0,0688355 0,10293239 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0688355 0,10286846 ! cofactor transport GO:0051181 26 14 0,000 0,0688355 0,1028046 ! NADP metabolic process GO:0006739 24 14 0,000 0,0688355 0,10274083 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0688355 0,10267713 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0688355 0,10261352 ! intestinal absorption GO:0050892 25 14 0,000 0,0688355 0,10254998 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0688355 0,10248652 ! oxygen transport GO:0015671 21 14 0,000 0,0688355 0,10242314 ! male genitalia development GO:0030539 24 14 0,000 0,0688355 0,10235984 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0688355 0,10229661 ! regulation of axon extension GO:0030516 37 14 0,000 0,0688355 0,10223347 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,0688355 0,1021704 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0688355 0,10210741 ! amine biosynthetic process GO:0009309 138 86 1,000 0,07107398 0,1053629 ! mitochondrion organization GO:0007005 148 86 1,000 0,07107398 0,10529802 ! alcohol catabolic process GO:0046164 130 86 1,000 0,07107398 0,10523322 ! amine transport GO:0015837 155 86 1,000 0,07107398 0,10516851 ! protein localization in nucleus GO:0034504 176 87 1,000 0,07251146 0,10722961 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07356819 0,10872547 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07356819 0,10865873 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,07356819 0,10859207 ! superoxide anion generation GO:0042554 20 15 0,000 0,07356819 0,10852549 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07356819 0,10845899 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07356819 0,10839257 ! copper ion transport GO:0006825 20 15 0,000 0,07356819 0,10832624 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,07356819 0,10825998 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07356819 0,10819381 ! sulfate transport GO:0008272 23 15 0,000 0,07356819 0,10812771 ! response to cAMP GO:0051591 22 15 0,000 0,07356819 0,1080617 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07356819 0,10799577 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07356819 0,10792992 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07356819 0,10786415 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,07356819 0,10779846 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07356819 0,10773285 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07356819 0,10766732 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07356819 0,10760187 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07356819 0,10753649 ! pituitary gland development GO:0021983 29 15 0,000 0,07356819 0,1074712 ! vesicle coating GO:0006901 33 15 0,000 0,07356819 0,10740599 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,07356819 0,10734085 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07356819 0,1072758 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,07356819 0,10721082 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,07356819 0,10714593 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07356819 0,10708111 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07356819 0,10701637 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07356819 0,1069517 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,07356819 0,10688712 ! histone deacetylation GO:0016575 20 15 0,000 0,07356819 0,10682261 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07356819 0,10675818 ! tissue regeneration GO:0042246 26 15 0,000 0,07356819 0,10669383 ! water homeostasis GO:0030104 27 15 0,000 0,07356819 0,10662956 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07356819 0,10656536 ! muscle maintenance GO:0046716 26 15 0,000 0,07356819 0,10650124 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07356819 0,1064372 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07356819 0,10637324 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07356819 0,10630935 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07356819 0,10624554 ! cell killing GO:0001906 29 15 0,000 0,07356819 0,1061818 ! detection of bacterium GO:0016045 18 15 0,000 0,07356819 0,10611815 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07356819 0,10605456 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07356819 0,10599106 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07356819 0,10592763 ! peptide hormone processing GO:0016486 23 15 0,000 0,07356819 0,10586428 ! regulation of DNA binding GO:0051101 155 88 1,000 0,07395835 0,10636209 ! gland development GO:0048732 206 88 1,000 0,07395835 0,10629856 ! regulation of neurological system process GO:0031644 148 88 1,000 0,07395835 0,10623509 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,0754145 0,10826211 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,07827698 0,11230437 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,07827698 0,11223744 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07827698 0,11217059 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07827698 0,11210382 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,07827698 0,11203713 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,07827698 0,11197052 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07827698 0,11190399 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,07827698 0,11183754 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,07827698 0,11177117 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,07827698 0,11170488 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,07827698 0,11163866 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,07827698 0,11157253 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,07827698 0,11150647 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07827698 0,11144049 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,07827698 0,11137458 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07827698 0,11130876 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07827698 0,11124301 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,07827698 0,11117735 ! response to osmotic stress GO:0006970 25 16 0,000 0,07827698 0,11111175 ! lysosomal transport GO:0007041 26 16 0,000 0,07827698 0,11104624 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07827698 0,1109808 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07827698 0,11091544 ! intermediate filament-based process GO:0045103 32 16 0,000 0,07827698 0,11085016 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,07827698 0,11078495 ! negative regulation of immune response GO:0050777 35 16 0,000 0,07827698 0,11071983 ! axon cargo transport GO:0008088 43 16 0,000 0,07827698 0,11065477 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07827698 0,1105898 ! DNA replication initiation GO:0006270 27 16 0,000 0,07827698 0,1105249 ! neuron recognition GO:0008038 35 16 0,000 0,07827698 0,11046007 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,07827698 0,11039532 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07827698 0,11033065 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,07827698 0,11026606 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,07827698 0,11020153 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07827698 0,11013709 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,07827698 0,11007272 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07827698 0,11000842 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07827698 0,1099442 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07827698 0,10988006 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,07827698 0,10981599 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,07827698 0,10975199 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07827698 0,10968807 ! defense response to virus GO:0051607 37 16 0,000 0,07827698 0,10962423 ! regulation of defense response GO:0031347 149 92 1,000 0,07983731 0,11174437 ! regulation of membrane potential GO:0042391 164 93 1,000 0,08132927 0,1137664 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,08282985 0,11579815 ! transcription initiation GO:0006352 153 94 1,000 0,08282985 0,11573091 ! regulation of T cell activation GO:0050863 158 94 1,000 0,08282985 0,11566374 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,082962 0,11578107 ! metencephalon development GO:0022037 30 17 0,000 0,082962 0,11571395 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,082962 0,11564691 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,082962 0,11557995 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,082962 0,11551306 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,082962 0,11544625 ! signal complex assembly GO:0007172 41 17 0,000 0,082962 0,11537952 ! endothelial cell migration GO:0043542 28 17 0,000 0,082962 0,11531286 ! inositol metabolic process GO:0006020 28 17 0,000 0,082962 0,11524629 ! gene silencing by RNA GO:0031047 36 17 0,000 0,082962 0,11517979 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,082962 0,11511336 ! glial cell development GO:0021782 27 17 0,000 0,082962 0,11504701 ! limbic system development GO:0021761 36 17 0,000 0,082962 0,11498074 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,082962 0,11491455 ! adult walking behavior GO:0007628 33 17 0,000 0,082962 0,11484843 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,082962 0,11478239 ! heart looping GO:0001947 30 17 0,000 0,082962 0,11471642 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,082962 0,11465053 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,082962 0,11458471 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,082962 0,11451897 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,082962 0,11445331 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,082962 0,11438772 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,082962 0,1143222 ! glycine metabolic process GO:0006544 28 17 0,000 0,082962 0,11425676 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,082962 0,1141914 ! NAD metabolic process GO:0019674 29 17 0,000 0,082962 0,11412611 ! membrane budding GO:0006900 37 17 0,000 0,082962 0,1140609 ! DNA integration GO:0015074 29 17 0,000 0,082962 0,11399576 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,082962 0,11393069 ! regulation of protein binding GO:0043393 33 17 0,000 0,082962 0,1138657 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,082962 0,11380078 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,082962 0,11373594 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,082962 0,11367117 ! genitalia development GO:0048806 30 17 0,000 0,082962 0,11360647 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,082962 0,11354185 ! neural crest cell migration GO:0001755 37 17 0,000 0,082962 0,1134773 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,082962 0,11341282 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,082962 0,11334842 ! steroid catabolic process GO:0006706 31 17 0,000 0,082962 0,11328409 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,082962 0,11321983 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,082962 0,11315565 ! gas transport GO:0015669 25 17 0,000 0,082962 0,11309154 ! organic cation transport GO:0015695 31 17 0,000 0,082962 0,1130275 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,082962 0,11296354 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,082962 0,11289964 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,082962 0,11283582 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,08433895 0,11464379 ! protein ubiquitination GO:0016567 217 97 1,000 0,08738216 0,11871342 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08762335 0,11897392 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08762335 0,11890682 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08762335 0,11883979 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,08762335 0,11877284 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08762335 0,11870596 ! memory GO:0007613 31 18 0,000 0,08762335 0,11863916 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08762335 0,11857244 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08762335 0,11850578 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08762335 0,11843921 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08762335 0,11837271 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08762335 0,11830628 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,08762335 0,11823993 ! response to retinoic acid GO:0032526 26 18 0,000 0,08762335 0,11817365 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,08762335 0,11810745 ! response to fungus GO:0009620 21 18 0,000 0,08762335 0,11804132 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,08762335 0,11797526 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08762335 0,11790928 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08762335 0,11784337 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08762335 0,11777754 ! vitamin transport GO:0051180 27 18 0,000 0,08762335 0,11771178 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,08762335 0,11764609 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08762335 0,11758047 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08762335 0,11751493 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08762335 0,11744947 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08762335 0,11738407 ! nerve development GO:0021675 28 18 0,000 0,08762335 0,11731875 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08762335 0,1172535 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,09045793 0,12097931 ! protein secretion GO:0009306 39 19 0,000 0,09226117 0,12332243 ! positive regulation of translation GO:0045727 30 19 0,000 0,09226117 0,12325396 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09226117 0,12318556 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09226117 0,12311724 ! skin development GO:0043588 36 19 0,000 0,09226117 0,12304899 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,09226117 0,12298082 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09226117 0,12291272 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09226117 0,1228447 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09226117 0,12277676 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09226117 0,12270889 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09226117 0,12264109 ! cerebral cortex development GO:0021987 36 19 0,000 0,09226117 0,12257337 ! pigmentation during development GO:0048066 41 19 0,000 0,09226117 0,12250573 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09226117 0,12243816 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,09226117 0,12237066 ! heme metabolic process GO:0042168 36 19 0,000 0,09226117 0,12230324 ! actin filament bundle formation GO:0051017 42 19 0,000 0,09226117 0,12223589 ! neuromuscular junction development GO:0007528 34 19 0,000 0,09226117 0,12216862 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09226117 0,12210142 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09226117 0,12203429 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,09226117 0,12196724 ! peptide cross-linking GO:0018149 37 19 0,000 0,09226117 0,12190026 ! protein export from nucleus GO:0006611 36 19 0,000 0,09226117 0,12183336 ! heart process GO:0003015 30 19 0,000 0,09226117 0,12176653 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09226117 0,12169977 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,09226117 0,12163308 ! visual learning GO:0008542 36 19 0,000 0,09226117 0,12156647 ! cellular pigmentation GO:0033059 36 19 0,000 0,09226117 0,12149993 ! G1 phase GO:0051318 40 19 0,000 0,09226117 0,12143347 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09226117 0,12136707 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,09226117 0,12130075 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09226117 0,1212345 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09226117 0,12116833 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09226117 0,12110222 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09226117 0,12103619 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09226117 0,12097023 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09226117 0,12090434 ! cilium assembly GO:0042384 37 19 0,000 0,09226117 0,12083853 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09226117 0,12077278 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,09687556 0,12674421 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,09687556 0,12667533 ! positive regulation of ossification GO:0045778 47 20 0,000 0,09687556 0,12660652 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,09687556 0,12653779 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,09687556 0,12646913 ! cAMP metabolic process GO:0046058 36 20 0,000 0,09687556 0,12640055 ! response to vitamin GO:0033273 31 20 0,000 0,09687556 0,12633204 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,09687556 0,1262636 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,09687556 0,12619524 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,09687556 0,12612695 ! response to alkaloid GO:0043279 38 20 0,000 0,09687556 0,12605874 ! retinoid metabolic process GO:0001523 32 20 0,000 0,09687556 0,1259906 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,09687556 0,12592253 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,09687556 0,12585454 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,09687556 0,12578662 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,09687556 0,12571877 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,09687556 0,125651 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,09687556 0,1255833 ! body fluid secretion GO:0007589 31 20 0,000 0,09687556 0,12551568 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,09687556 0,12544812 ! peptide secretion GO:0002790 35 20 0,000 0,09687556 0,12538064 ! stem cell differentiation GO:0048863 53 20 0,000 0,09687556 0,12531323 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,09687556 0,12524589 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,09687556 0,12517863 ! sensory perception of pain GO:0019233 30 20 0,000 0,09687556 0,12511144 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,09687556 0,12504432 ! diencephalon development GO:0021536 34 20 0,000 0,09687556 0,12497727 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,09687556 0,12491029 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,09687556 0,12484339 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,09687556 0,12477656 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,09687556 0,1247098 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,09687556 0,12464311 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,09687556 0,12457649 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,09687556 0,12450994 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,09687556 0,12444346 ! actin filament-based movement GO:0030048 43 20 0,000 0,09687556 0,12437706 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,09687556 0,12431072 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,09687556 0,12424446 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,09687556 0,12417827 ! negative regulation of translation GO:0017148 29 20 0,000 0,09687556 0,12411215 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,09687556 0,12404609 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,09687556 0,12398011 ! regulation of cell killing GO:0031341 42 21 0,000 0,10146665 0,12978669 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10146665 0,12971773 ! hormone secretion GO:0046879 38 21 0,000 0,10146665 0,12964884 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10146665 0,12958003 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10146665 0,12951128 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10146665 0,12944261 ! axis specification GO:0009798 38 21 0,000 0,10146665 0,12937402 ! ovarian follicle development GO:0001541 35 21 0,000 0,10146665 0,12930549 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10146665 0,12923704 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10146665 0,12916866 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,10146665 0,12910036 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10146665 0,12903212 ! cell aging GO:0007569 44 21 0,000 0,10146665 0,12896396 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,10146665 0,12889587 ! cytolysis GO:0019835 24 21 0,000 0,10146665 0,12882785 ! vasodilation GO:0042311 39 21 0,000 0,10146665 0,1287599 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10146665 0,12869203 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10146665 0,12862422 ! oogenesis GO:0048477 36 21 0,000 0,10146665 0,12855649 ! DNA modification GO:0006304 34 21 0,000 0,10146665 0,12848883 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,10146665 0,12842124 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,10146665 0,12835372 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10146665 0,12828627 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10146665 0,12821889 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,10146665 0,12815159 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10146665 0,12808435 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10146665 0,12801718 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,10146665 0,12795009 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10146665 0,12788307 ! collagen catabolic process GO:0030574 28 21 0,000 0,10146665 0,12781611 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10146665 0,12774923 ! gut development GO:0048565 39 21 0,000 0,10146665 0,12768241 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,10603456 0,13336077 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,10603456 0,13329109 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,10603456 0,13322149 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,10603456 0,13315195 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,10603456 0,1330825 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,10603456 0,13301311 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,10603456 0,1329438 ! regeneration GO:0031099 41 22 0,000 0,10603456 0,13287455 ! keratinization GO:0031424 28 22 0,000 0,10603456 0,13280539 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,10603456 0,13273629 ! sensory perception of taste GO:0050909 28 22 0,000 0,10603456 0,13266726 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,10603456 0,13259831 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,10603456 0,13252943 ! vacuolar transport GO:0007034 36 22 0,000 0,10603456 0,13246062 ! lysosome organization GO:0007040 41 22 0,000 0,10603456 0,13239188 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,10603456 0,13232321 ! fucose metabolic process GO:0006004 39 22 0,000 0,10603456 0,13225461 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,10603456 0,13218609 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,10603456 0,13211763 ! ureteric bud development GO:0001657 43 22 0,000 0,10603456 0,13204925 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,10603456 0,13198093 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,10603456 0,13191269 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,10603456 0,13184452 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,10603456 0,13177642 ! sarcomere organization GO:0045214 30 22 0,000 0,10603456 0,13170839 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,10603456 0,13164043 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,10603456 0,13157254 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,10603456 0,13150471 ! protein stabilization GO:0050821 39 22 0,000 0,10603456 0,13143696 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,11057939 0,13700001 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,11057939 0,1369295 ! gluconeogenesis GO:0006094 33 23 0,000 0,11057939 0,13685906 ! viral genome replication GO:0019079 41 23 0,000 0,11057939 0,13678869 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,11057939 0,1367184 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,11057939 0,13664818 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,11057939 0,13657803 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,11057939 0,13650796 ! visual behavior GO:0007632 42 23 0,000 0,11057939 0,13643795 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,11057939 0,13636802 ! response to ethanol GO:0045471 46 23 0,000 0,11057939 0,13629816 ! peroxisome organization GO:0007031 37 23 0,000 0,11057939 0,13622837 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,11057939 0,13615865 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,11057939 0,13608901 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,11057939 0,13601943 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,11057939 0,13594993 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,11057939 0,1358805 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,11057939 0,13581113 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,11057939 0,13574184 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,11057939 0,13567262 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,11057939 0,13560347 ! fatty acid transport GO:0015908 44 23 0,000 0,11057939 0,13553439 ! platelet activation GO:0030168 37 23 0,000 0,11057939 0,13546538 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,11057939 0,13539644 ! hormone transport GO:0009914 40 23 0,000 0,11057939 0,13532757 ! cell-cell recognition GO:0009988 25 23 0,000 0,11057939 0,13525878 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,11057939 0,13519005 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,11057939 0,13512139 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,11057939 0,1350528 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,11057939 0,13498428 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,11057939 0,13491583 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,11510127 0,14036171 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,11510127 0,1402906 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,11510127 0,14021957 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,11510127 0,14014861 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,11510127 0,14007772 ! spinal cord development GO:0021510 47 24 0,000 0,11510127 0,1400069 ! vacuole organization GO:0007033 43 24 0,000 0,11510127 0,13993615 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,11510127 0,13986548 ! digestive system process GO:0022600 39 24 0,000 0,11510127 0,13979487 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,11510127 0,13972434 ! regulation of behavior GO:0050795 43 24 0,000 0,11510127 0,13965388 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,11510127 0,13958349 ! pallium development GO:0021543 49 24 0,000 0,11510127 0,13951317 ! pentose metabolic process GO:0019321 35 24 0,000 0,11510127 0,13944292 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,11510127 0,13937275 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,11510127 0,13930264 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,11510127 0,1392326 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,11510127 0,13916264 ! regulation of amine transport GO:0051952 40 24 0,000 0,11510127 0,13909274 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,1196003 0,14445699 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,1196003 0,14438451 ! myelination GO:0042552 45 25 0,000 0,1196003 0,1443121 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,1196003 0,14423976 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,1196003 0,1441675 ! phototransduction GO:0007602 33 25 0,000 0,1196003 0,14409531 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,1196003 0,14402319 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,1196003 0,14395114 ! sperm motility GO:0030317 31 25 0,000 0,1196003 0,14387916 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,1196003 0,14380726 ! receptor metabolic process GO:0043112 46 25 0,000 0,1196003 0,14373543 ! chromosome condensation GO:0030261 45 25 0,000 0,1196003 0,14366367 ! response to starvation GO:0042594 42 25 0,000 0,1196003 0,14359198 ! neural crest cell development GO:0014032 54 25 0,000 0,1196003 0,14352036 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,1196003 0,14344882 ! negative regulation of cell development GO:0010721 73 25 0,000 0,1196003 0,14337734 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,1196003 0,14330594 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,1196003 0,14323461 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,1196003 0,14316335 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,1196003 0,14309216 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,1196003 0,14302104 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,1196003 0,14294999 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,1196003 0,14287901 ! telomere organization GO:0032200 43 25 0,000 0,1196003 0,1428081 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,1196003 0,14273727 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,1196003 0,1426665 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,12407661 0,14793277 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,12407661 0,1478595 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,12407661 0,1477863 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,12407661 0,14771318 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,12407661 0,14764012 ! tube lumen formation GO:0035148 50 26 0,000 0,12407661 0,14756714 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,12407661 0,14749424 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,12407661 0,1474214 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,12407661 0,14734863 GO:0051297|centrosome organization, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,12407661 0,14727594 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,12407661 0,14720332 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,12407661 0,14713077 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,12407661 0,14705829 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,12407661 0,14698588 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,12407661 0,14691355 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,12407661 0,14684128 ! blastocyst development GO:0001824 49 26 0,000 0,12407661 0,14676909 ! leukocyte proliferation GO:0070661 52 26 0,000 0,12407661 0,14669697 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,12407661 0,14662492 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,12853031 0,15181342 ! neuron fate commitment GO:0048663 48 27 0,000 0,12853031 0,15173893 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,12853031 0,15166451 ! iron ion transport GO:0006826 59 27 0,000 0,12853031 0,15159016 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,12853031 0,15151589 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,12853031 0,15144169 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,12853031 0,15136756 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,12853031 0,15129351 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,12853031 0,15121953 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,12853031 0,15114562 ! autophagy GO:0006914 41 27 0,000 0,12853031 0,15107178 ! male gonad development GO:0008584 44 27 0,000 0,12853031 0,15099801 ! response to toxin GO:0009636 47 27 0,000 0,12853031 0,15092432 ! primary neural tube formation GO:0014020 51 27 0,000 0,12853031 0,1508507 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,12853031 0,15077715 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,12853031 0,15070367 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,12853031 0,15063026 ! glutathione metabolic process GO:0006749 39 27 0,000 0,12853031 0,15055693 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,12853031 0,15048367 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,12853031 0,15041047 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,12853031 0,15033735 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,12853031 0,1502643 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,13296152 0,15536931 ! circadian rhythm GO:0007623 50 28 0,000 0,13296152 0,15529389 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,13296152 0,15521854 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,13296152 0,15514326 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,13296152 0,15506806 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,13296152 0,15499293 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,13296152 0,15491787 ! synaptogenesis GO:0007416 42 28 0,000 0,13296152 0,15484289 ! lipid oxidation GO:0034440 43 28 0,000 0,13296152 0,15476798 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,13296152 0,15469314 ! translational initiation GO:0006413 65 29 0,000 0,13737033 0,1597453 ! regulation of pH GO:0006885 43 29 0,000 0,13737033 0,15966812 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,13737033 0,15959103 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,13737033 0,15951401 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,13737033 0,15943706 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,13737033 0,15936018 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,13737033 0,15928338 ! cell fate determination GO:0001709 60 29 0,000 0,13737033 0,15920666 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,13737033 0,15913 ! detection of light stimulus GO:0009583 38 29 0,000 0,13737033 0,15905343 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,13737033 0,15897692 ! tissue homeostasis GO:0001894 48 29 0,000 0,13737033 0,15890049 GO:0048871|multicellular organismal homeostasis, ! zinc ion transport GO:0006829 45 30 0,000 0,14175688 0,16389574 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,14175688 0,16381702 ! cell junction assembly GO:0034329 78 30 0,000 0,14175688 0,16373838 ! regulation of innate immune response GO:0045088 51 30 0,000 0,14175688 0,16365981 ! acute-phase response GO:0006953 49 30 0,000 0,14175688 0,16358132 ! myofibril assembly GO:0030239 47 30 0,000 0,14175688 0,1635029 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,14175688 0,16342455 ! phospholipid transport GO:0015914 51 30 0,000 0,14175688 0,16334629 ! ensheathment of neurons GO:0007272 57 30 0,000 0,14175688 0,16326809 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,14175688 0,16318997 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,14175688 0,16311193 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,14175688 0,16303396 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,14175688 0,16295606 ! eye morphogenesis GO:0048592 60 30 0,000 0,14175688 0,16287824 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,14612126 0,16781277 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,14612126 0,1677327 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,14612126 0,16765272 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,14612126 0,16757281 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,14612126 0,16749297 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,14612126 0,16741321 ! ovulation cycle process GO:0022602 49 31 0,000 0,14612126 0,16733353 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,14612126 0,16725392 ! peptide transport GO:0015833 55 31 0,000 0,14612126 0,16717439 ! iron ion homeostasis GO:0055072 54 31 0,000 0,14612126 0,16709494 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,14612126 0,16701556 ! natural killer cell activation GO:0030101 45 31 0,000 0,14612126 0,16693625 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,14612126 0,16685702 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,14612126 0,16677787 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,14612126 0,16669879 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,15046359 0,17157128 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,15046359 0,17149001 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15046359 0,17140881 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,15046359 0,17132769 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15046359 0,17124664 ! spliceosome assembly GO:0000245 67 32 0,000 0,15046359 0,17116568 ! spindle organization GO:0007051 46 32 0,000 0,15046359 0,17108478 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,15046359 0,17100397 ! metanephros development GO:0001656 74 32 0,000 0,15046359 0,17092323 ! response to ionizing radiation GO:0010212 65 32 0,000 0,15046359 0,17084257 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,15046359 0,17076198 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,15046359 0,17068147 ! muscle cell development GO:0055001 49 32 0,000 0,15046359 0,17060104 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15046359 0,17052068 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,15046359 0,1704404 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,15046359 0,17036019 ! ovulation cycle GO:0042698 51 32 0,000 0,15046359 0,17028006 ! peripheral nervous system development GO:0007422 64 32 0,000 0,15046359 0,1702 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,15046359 0,17012002 ! gene silencing GO:0016458 65 32 0,000 0,15046359 0,17004011 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,15478399 0,1748405 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,15478399 0,17475846 ! protein targeting to membrane GO:0006612 68 33 0,000 0,15478399 0,17467649 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,15478399 0,1745946 ! ceramide metabolic process GO:0006672 64 33 0,000 0,15478399 0,17451278 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,15478399 0,17443104 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,15478399 0,17434938 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,15478399 0,17426779 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,15908255 0,17902368 ! glial cell differentiation GO:0010001 63 34 0,000 0,15908255 0,17893998 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,15908255 0,17885637 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,15908255 0,17877283 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,15908255 0,17868937 ! mismatch repair GO:0006298 46 34 0,000 0,15908255 0,17860598 ! spermatid development GO:0007286 63 34 0,000 0,15908255 0,17852268 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,15908255 0,17843945 ! regulation of muscle development GO:0048634 70 35 0,000 0,1633594 0,18315131 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,1633594 0,18306601 ! negative regulation of secretion GO:0051048 63 35 0,000 0,1633594 0,18298078 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,1633594 0,18289563 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,1633594 0,18281057 ! odontogenesis GO:0042476 66 35 0,000 0,1633594 0,18272558 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,1633594 0,18264067 ! female gonad development GO:0008585 58 35 0,000 0,1633594 0,18255584 ! telencephalon development GO:0021537 68 35 0,000 0,1633594 0,18247108 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,1633594 0,18238641 ! cytokine production GO:0001816 59 35 0,000 0,1633594 0,18230182 ! neural tube formation GO:0001841 67 35 0,000 0,1633594 0,1822173 ! vesicle localization GO:0051648 64 35 0,000 0,1633594 0,18213286 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,16761464 0,18679056 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,16761464 0,18670408 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,16761464 0,18661768 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,16761464 0,18653137 ! cell junction organization GO:0034330 86 36 0,000 0,16761464 0,18644513 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,16761464 0,18635897 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,16761464 0,18627289 ! positive regulation of cell development GO:0010720 80 36 0,000 0,16761464 0,18618689 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,16761464 0,18610098 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,16761464 0,18601514 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,16761464 0,18592937 ! aerobic respiration GO:0009060 55 36 0,000 0,16761464 0,18584369 ! embryonic organ development GO:0048568 57 36 0,000 0,16761464 0,18575809 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,16761464 0,18567257 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,16761464 0,18558712 ! RNA export from nucleus GO:0006405 56 37 0,000 0,17184837 0,19018729 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,17184837 0,19009985 ! meiosis I GO:0007127 65 37 0,000 0,17184837 0,19001249 ! sister chromatid segregation GO:0000819 58 37 0,000 0,17184837 0,18992521 ! actomyosin structure organization GO:0031032 62 37 0,000 0,17184837 0,18983801 ! organic anion transport GO:0015711 68 37 0,000 0,17184837 0,18975088 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,17184837 0,18966384 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,17184837 0,18957688 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,17184837 0,18949 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,17184837 0,1894032 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,17184837 0,18931647 ! pigment metabolic process GO:0042440 80 37 0,000 0,17184837 0,18922983 ! spermatid differentiation GO:0048515 66 37 0,000 0,17184837 0,18914327 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,17606071 0,19369093 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,17606071 0,19360241 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,17606071 0,19351396 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,17606071 0,1934256 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,17606071 0,19333732 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,17606071 0,19324912 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,17606071 0,193161 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,17606071 0,19307296 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,17606071 0,192985 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,17606071 0,19289712 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,17606071 0,19280932 ! mRNA catabolic process GO:0006402 71 39 0,000 0,18025176 0,19730926 ! learning GO:0007612 77 39 0,000 0,18025176 0,19721953 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,18025176 0,19712988 ! ion transmembrane transport GO:0034220 66 39 0,000 0,18025176 0,19704032 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,18025176 0,19695084 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,18025176 0,19686144 ! RNA modification GO:0009451 57 39 0,000 0,18025176 0,19677212 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,18025176 0,19668288 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,18442164 0,20114164 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,18442164 0,2010505 ! feeding behavior GO:0007631 59 40 0,000 0,18442164 0,20095945 ! negative regulation of binding GO:0051100 72 40 0,000 0,18442164 0,20086848 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,18442164 0,20077758 ! maintenance of protein location GO:0045185 91 40 0,000 0,18442164 0,20068678 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,18857044 0,20510871 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,18857044 0,20501603 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,18857044 0,20492343 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,18857044 0,20483092 ! gliogenesis GO:0042063 88 41 0,000 0,18857044 0,20473848 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,18857044 0,20464613 ! female gamete generation GO:0007292 61 41 0,000 0,18857044 0,20455387 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,18857044 0,20446168 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,19269827 0,20884326 ! regulation of tube size GO:0035150 71 42 0,000 0,19269827 0,20874923 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,19269827 0,20865529 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,19269827 0,20856142 ! regulation of protein secretion GO:0050708 71 42 0,000 0,19269827 0,20846765 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,19269827 0,20837395 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,19680524 0,21271942 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,19680524 0,2126239 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,19680524 0,21252846 ! neural tube development GO:0021915 77 43 0,000 0,19680524 0,21243312 ! striated muscle contraction GO:0006941 77 43 0,000 0,19680524 0,21233786 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,19680524 0,21224268 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,20089146 0,21655235 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,20089146 0,21645537 ! male sex differentiation GO:0046661 76 44 0,000 0,20089146 0,21635848 ! double-strand break repair GO:0006302 81 44 0,000 0,20089146 0,21626168 ! biopolymer methylation GO:0043414 84 44 0,000 0,20089146 0,21616496 ! B cell differentiation GO:0030183 107 44 0,000 0,20089146 0,21606833 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,20089146 0,21597178 ! maintenance of location in cell GO:0051651 97 44 0,000 0,20089146 0,21587532 ! glycolysis GO:0006096 65 45 0,000 0,20495702 0,2201458 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,20495702 0,22004756 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,20495702 0,21994941 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,20495702 0,21985135 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,20495702 0,21975338 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,20495702 0,2196555 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,20900203 0,22389087 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,20900203 0,22379123 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,20900203 0,22369167 ! pigmentation GO:0043473 100 46 0,000 0,20900203 0,22359221 ! endosome transport GO:0016197 108 47 0,000 0,2130266 0,22779644 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,2130266 0,22769524 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,2130266 0,22759413 ! methylation GO:0032259 90 47 0,000 0,2130266 0,22749311 ! mitochondrial transport GO:0006839 82 48 0,000 0,21703082 0,23166643 ! Notch signaling pathway GO:0007219 96 48 0,000 0,21703082 0,2315637 ! cellular component disassembly GO:0022411 86 48 0,000 0,21703082 0,23146106 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,21703082 0,2313585 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,21703082 0,23125604 ! activation of caspase activity GO:0006919 84 48 0,000 0,21703082 0,23115367 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,21703082 0,23105139 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,2210148 0,23518868 ! regulation of action potential GO:0001508 95 49 0,000 0,2210148 0,2350847 ! regulation of ion transport GO:0043269 77 49 0,000 0,2210148 0,23498082 ! peptide metabolic process GO:0006518 76 49 0,000 0,2210148 0,23487703 ! endocrine system development GO:0035270 104 49 0,000 0,2210148 0,23477333 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,2210148 0,23466973 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,2210148 0,23456621 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,2210148 0,23446279 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,22497864 0,23856263 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,22497864 0,23845753 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,22892244 0,24253077 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,22892244 0,24242402 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,22892244 0,24231737 ! excretion GO:0007588 83 51 0,000 0,22892244 0,24221081 ! chromatin remodeling GO:0006338 109 51 0,000 0,22892244 0,24210434 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,22892244 0,24199797 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,22892244 0,24189169 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,2328463 0,24592985 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,2328463 0,24582194 ! amino acid activation GO:0043038 92 52 0,000 0,2328463 0,24571412 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,2328463 0,2456064 ! synapse organization GO:0050808 85 52 0,000 0,2328463 0,24549877 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,23675033 0,2495056 ! RNA catabolic process GO:0006401 93 53 0,000 0,23675033 0,24939636 ! regulation of translational initiation GO:0006446 82 53 0,000 0,23675033 0,24928721 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,23675033 0,24917816 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,23675033 0,24906921 ! cell recognition GO:0008037 85 54 0,000 0,24063461 0,25304496 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,24063461 0,25293442 ! chloride transport GO:0006821 90 55 0,000 0,24449926 0,25688438 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,24449926 0,25677225 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,24449926 0,25666022 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,24449926 0,25654829 ! aging GO:0007568 103 55 0,000 0,24449926 0,25643645 ! nuclear export GO:0051168 97 55 0,000 0,24449926 0,25632471 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,24449926 0,25621307 ! sensory perception of smell GO:0007608 80 56 0,000 0,24834437 0,2601291 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,24834437 0,2600159 ! proton transport GO:0015992 94 56 0,000 0,24834437 0,2599028 ! hydrogen transport GO:0006818 97 58 0,000 0,25597635 0,26777352 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,25976342 0,27161704 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,25976342 0,27149904 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,25976342 0,27138115 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,26353135 0,2751981 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,26353135 0,27507871 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,26353135 0,27495942 ! regulation of heart contraction GO:0008016 110 60 0,000 0,26353135 0,27484023 ! camera-type eye development GO:0043010 116 60 0,000 0,26353135 0,27472115 ! kidney development GO:0001822 122 60 0,000 0,26353135 0,27460217 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,26728021 0,27838796 ! tRNA processing GO:0008033 89 61 0,000 0,26728021 0,2782675 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,26728021 0,27814714 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,27101012 0,28190677 ! gonad development GO:0008406 98 62 0,000 0,27101012 0,28178494 ! regulation of mitosis GO:0007088 105 63 0,000 0,27472117 0,28552014 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,27472117 0,28539686 ! detection of external stimulus GO:0009581 91 63 0,000 0,27472117 0,28527368 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,27472117 0,28515062 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,27841344 0,28885845 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,27841344 0,28873394 GO:0048609|reproductive process in a multicellular organism, ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,28208704 0,29241768 ! actin filament organization GO:0007015 148 66 0,000 0,28574207 0,29607899 ! extracellular matrix organization GO:0030198 133 66 0,000 0,28574207 0,29595153 ! secondary metabolic process GO:0019748 116 66 0,000 0,28574207 0,29582419 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,2893786 0,29946018 ! chromosome segregation GO:0007059 113 67 0,000 0,2893786 0,29933143 ! hexose catabolic process GO:0019320 104 67 0,000 0,2893786 0,2992028 ! amino acid transport GO:0006865 125 68 0,000 0,29299674 0,30281364 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,29299674 0,30268362 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,29299674 0,30255371 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,29659657 0,30613958 ! urogenital system development GO:0001655 137 69 0,000 0,29659657 0,3060083 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,29659657 0,30587714 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,29659657 0,30574608 ! amine catabolic process GO:0009310 117 71 0,000 0,30374171 0,31297754 ! reproductive structure development GO:0048608 113 71 0,000 0,30374171 0,31284356 ! humoral immune response GO:0006959 109 71 0,000 0,30374171 0,31270969 ! B cell activation GO:0042113 160 71 0,000 0,30374171 0,31257594 ! acute inflammatory response GO:0002526 113 72 0,000 0,30728719 0,31608935 ! learning or memory GO:0007611 147 73 0,000 0,31081473 0,3195813 ! regulation of blood pressure GO:0008217 125 73 0,000 0,31081473 0,31944479 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,31081473 0,31930839 ! axon guidance GO:0007411 139 73 0,000 0,31081473 0,31917211 ! transition metal ion transport GO:0000041 126 74 0,000 0,31432443 0,32263847 ! neurotransmitter transport GO:0006836 123 74 0,000 0,31432443 0,32250089 ! meiosis GO:0007126 121 74 0,000 0,31432443 0,32236342 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,31432443 0,32222607 ! eye development GO:0001654 143 74 0,000 0,31432443 0,32208883 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,31781637 0,32552839 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,31781637 0,32538987 ! meiotic cell cycle GO:0051321 122 75 0,000 0,31781637 0,32525146 ! rhythmic process GO:0048511 128 75 0,000 0,31781637 0,32511318 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,32129064 0,32852754 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,32129064 0,32838797 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,32129064 0,32824853 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,32129064 0,32810921 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,32474734 0,33149856 ! blood coagulation GO:0007596 146 78 0,000 0,32818654 0,33486718 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,32818654 0,33472523 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,33160834 0,33807189 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,33160834 0,3379287 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,33160834 0,33778563 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,33501283 0,34110912 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,33501283 0,34096483 ! digestion GO:0007586 112 81 0,000 0,33840008 0,34426664 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,33840008 0,34412113 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,33840008 0,34397575 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,33840008 0,34383049 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,3417702 0,3471081 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,3417702 0,34696164 ! response to drug GO:0042493 143 82 0,000 0,3417702 0,34681531 ! response to nutrient GO:0007584 125 82 0,000 0,3417702 0,3466691 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,3417702 0,34652301 ! regulation of lyase activity GO:0051339 160 83 0,000 0,34512326 0,3497753 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,34845935 0,35300766 ! hemostasis GO:0007599 158 84 0,000 0,34845935 0,35285909 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,34845935 0,35271064 ! response to unfolded protein GO:0006986 131 85 0,000 0,35177856 0,35592061 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,35177856 0,355771 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,35508096 0,35896 ! tube morphogenesis GO:0035239 176 86 0,000 0,35508096 0,35880924 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,35836665 0,3619774 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,35836665 0,3618255 ! cellular respiration GO:0045333 135 88 0,000 0,36163572 0,36497296 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,36163572 0,36481993 ! cellular defense response GO:0006968 114 89 0,000 0,36488823 0,36794681 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,36812428 0,37105447 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,36812428 0,37089908 ! sex differentiation GO:0007548 145 90 0,000 0,36812428 0,37074383 ! sterol metabolic process GO:0016125 152 91 0,000 0,37134395 0,37382993 ! response to protein stimulus GO:0051789 149 91 0,000 0,37134395 0,37367358 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,37134395 0,37351736 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,37454732 0,37658205 ! vitamin metabolic process GO:0006766 139 92 0,000 0,37454732 0,37642475 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,37773447 0,37946937 ! female pregnancy GO:0007565 164 94 0,000 0,38090549 0,38249524 ! forebrain development GO:0030900 188 95 0,000 0,38406045 0,38550248 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,38719944 0,38849118 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,38719944 0,38832924 ! detection of stimulus GO:0051606 151 96 0,000 0,38719944 0,38816744 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,39032254 0,39113537 ! hormone metabolic process GO:0042445 157 97 0,000 0,39032254 0,39097253 ! response to virus GO:0009615 160 98 0,000 0,39342982 0,39392099 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,39342982 0,39375713 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,39342982 0,39359341 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,39652137 0,39652137