pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1135-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 5,000 4,787E-12 1,169E-08 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 6,000 4,082E-08 4,987E-05 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 4,000 4,381E-08 3,568E-05 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 6,000 5,508E-08 3,364E-05 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 6,000 5,508E-08 2,691E-05 ! positive regulation of ligase activity GO:0051351 130 77 6,000 8,814E-08 3,589E-05 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 6,000 1,054E-07 3,678E-05 ! regulation of ligase activity GO:0051340 147 84 6,000 1,614E-07 4,93E-05 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 5,000 9,063E-07 2,46E-04 ! cellular response to insulin stimulus GO:0032869 85 38 4,000 1,012E-06 2,473E-04 ! regulation of leukocyte degranulation GO:0043300 8 5 2,000 1,049E-06 2,329E-04 ! positive regulation of mast cell activation GO:0033005 12 5 2,000 1,049E-06 2,135E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 3,000 1,433E-06 2,692E-04 ! myoblast cell fate commitment GO:0048625 18 6 2,000 2,09E-06 3,647E-04 ! nuclear migration GO:0007097 13 6 2,000 2,09E-06 3,404E-04 ! positive regulation of exocytosis GO:0045921 11 6 2,000 2,09E-06 3,191E-04 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 2,000 2,09E-06 3,003E-04 ! regulation of mast cell activation GO:0033003 13 6 2,000 2,09E-06 2,836E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 2,09E-06 2,687E-04 GO:0031272|regulation of pseudopodium assembly, ! response to insulin stimulus GO:0032868 98 47 4,000 2,988E-06 3,65E-04 ! cellular response to hormone stimulus GO:0032870 182 85 5,000 3,388E-06 3,941E-04 ! calcium-independent cell-cell adhesion GO:0016338 36 24 3,000 4,865E-06 5,403E-04 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 5,000 5,722E-06 6,078E-04 GO:0010498|proteasomal protein catabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 5,811E-06 5,915E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 5,811E-06 5,678E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 5,811E-06 5,46E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 5,811E-06 5,258E-04 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 7,947E-06 6,934E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 8,685E-06 7,317E-04 ! macrophage differentiation GO:0030225 15 9 2,000 8,685E-06 7,073E-04 ! positive regulation of secretion GO:0051047 110 61 4,000 1,098E-05 8,656E-04 ! phagocytosis, engulfment GO:0006911 33 10 2,000 1,236E-05 9,439E-04 ! regulation of protein complex assembly GO:0043254 132 63 4,000 1,288E-05 9,534E-04 ! protein amino acid autophosphorylation GO:0046777 157 64 4,000 1,392E-05 1E-03 ! response to peptide hormone stimulus GO:0043434 129 64 4,000 1,392E-05 9,714E-04 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 1,694E-05 1,15E-03 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 1,694E-05 1,119E-03 ! nucleus localization GO:0051647 22 11 2,000 1,694E-05 1,089E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 4,000 1,743E-05 1,092E-03 ! negative regulation of ligase activity GO:0051352 116 68 4,000 1,874E-05 1,144E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of cellular catabolic process GO:0031331 34 12 2,000 2,251E-05 1,341E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 2,251E-05 1,309E-03 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 2,251E-05 1,279E-03 ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 2,916E-05 1,619E-03 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 2,916E-05 1,583E-03 ! carbohydrate homeostasis GO:0033500 59 39 3,000 3,562E-05 1,892E-03 GO:0042593|glucose homeostasis, ! lipid localization GO:0010876 32 14 2,000 3,698E-05 1,922E-03 GO:0019915|lipid storage, ! regulation of exocytosis GO:0017157 26 15 2,000 4,607E-05 2,345E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 4,607E-05 2,297E-03 ! energy reserve metabolic process GO:0006112 76 44 3,000 5,772E-05 2,82E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 6,311E-05 3,023E-03 ! filopodium assembly GO:0046847 42 17 2,000 6,837E-05 3,212E-03 ! myoblast differentiation GO:0045445 50 17 2,000 6,837E-05 3,151E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 6,837E-05 3,093E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 2,000 8,176E-05 3,631E-03 ! microspike assembly GO:0030035 46 18 2,000 8,176E-05 3,567E-03 ! regulation of ossification GO:0030278 123 50 3,000 9,577E-05 4,104E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 9,675E-05 4,075E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 1,134E-04 4,696E-03 ! regulation of carbohydrate metabolic process GO:0006109 37 20 2,000 1,134E-04 4,618E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! pancreas development GO:0031016 40 20 2,000 1,134E-04 4,542E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 1,134E-04 4,469E-03 ! skeletal muscle tissue development GO:0007519 223 100 4,000 1,197E-04 4,643E-03 GO:0060538|skeletal muscle organ development, ! phosphatidylinositol metabolic process GO:0046488 47 21 2,000 1,319E-04 5,033E-03 ! positive regulation of osteoblast differentiation GO:0045669 52 21 2,000 1,319E-04 4,956E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 1,521E-04 5,632E-03 ! peptidyl-serine modification GO:0018209 50 22 2,000 1,521E-04 5,548E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 1,601E-04 5,75E-03 ! regulation of bone remodeling GO:0046850 143 57 3,000 1,601E-04 5,667E-03 ! regulation of tissue remodeling GO:0034103 146 58 3,000 1,713E-04 5,978E-03 ! regulation of cellular catabolic process GO:0031329 55 24 2,000 1,986E-04 6,833E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,986E-04 6,738E-03 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 2,000 1,986E-04 6,645E-03 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 1,986E-04 6,556E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 2,000 1,986E-04 6,468E-03 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 1,000 2,226E-04 7,156E-03 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,226E-04 7,064E-03 ! anagen GO:0042640 7 5 1,000 2,226E-04 6,973E-03 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 1,000 2,226E-04 6,885E-03 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! microvillus organization GO:0032528 8 5 1,000 2,226E-04 6,799E-03 GO:0030033|microvillus assembly, ! polyol catabolic process GO:0046174 9 5 1,000 2,226E-04 6,715E-03 GO:0019405|alditol catabolic process, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,226E-04 6,633E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 1,000 2,226E-04 6,553E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 2,226E-04 6,475E-03 ! response to food GO:0032094 6 5 1,000 2,226E-04 6,399E-03 ! regulation of glycogen metabolic process GO:0070873 10 5 1,000 2,226E-04 6,324E-03 GO:0032881|regulation of polysaccharide metabolic process, ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 1,000 2,226E-04 6,252E-03 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! regulation of sensory perception GO:0051931 8 5 1,000 2,226E-04 6,181E-03 GO:0051930|regulation of sensory perception of pain, ! protein insertion into membrane GO:0051205 17 5 1,000 2,226E-04 6,111E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 2,249E-04 6,104E-03 ! vasculogenesis GO:0001570 49 25 2,000 2,249E-04 6,037E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 2,249E-04 5,971E-03 ! interaction with host GO:0051701 66 25 2,000 2,249E-04 5,907E-03 ! regulation of osteoblast differentiation GO:0045667 68 26 2,000 2,533E-04 6,583E-03 ! regulation of lipid metabolic process GO:0019216 132 66 3,000 2,825E-04 7,265E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 2,84E-04 7,227E-03 ! cell projection assembly GO:0030031 138 68 3,000 3,169E-04 7,98E-03 ! fat cell differentiation GO:0045444 57 28 2,000 3,17E-04 7,901E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 3,329E-04 8,215E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 3,329E-04 8,133E-03 ! positive regulation of cytokine production during immune response GO:0002720 11 6 1,000 3,329E-04 8,052E-03 ! positive regulation of B cell differentiation GO:0045579 13 6 1,000 3,329E-04 7,973E-03 ! hair follicle maturation GO:0048820 8 6 1,000 3,329E-04 7,896E-03 ! regulation of myeloid cell apoptosis GO:0033032 14 6 1,000 3,329E-04 7,82E-03 ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 1,000 3,329E-04 7,746E-03 ! cellular anion homeostasis GO:0030002 11 6 1,000 3,329E-04 7,673E-03 GO:0055081|anion homeostasis, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 3,351E-04 7,651E-03 ! regulation of peptide secretion GO:0002791 52 29 2,000 3,523E-04 7,969E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 3,523E-04 7,896E-03 ! negative regulation of neuron apoptosis GO:0043524 69 29 2,000 3,523E-04 7,824E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 3,901E-04 8,585E-03 ! immune response-activating signal transduction GO:0002757 58 30 2,000 3,901E-04 8,508E-03 GO:0002764|immune response-regulating signal transduction, ! regulation of MAPKKK cascade GO:0043408 157 72 3,000 3,944E-04 8,527E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 2,000 4,304E-04 9,223E-03 ! positive regulation of immune effector process GO:0002699 78 31 2,000 4,304E-04 9,142E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,646E-04 9,785E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 4,646E-04 9,701E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 4,646E-04 9,619E-03 ! regulation of dopamine metabolic process GO:0042053 12 7 1,000 4,646E-04 9,538E-03 GO:0042069|regulation of catecholamine metabolic process, ! vesicle fusion GO:0006906 20 7 1,000 4,646E-04 9,459E-03 ! male sex determination GO:0030238 15 7 1,000 4,646E-04 9,38E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 1,000 4,646E-04 9,304E-03 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 1,000 4,646E-04 9,228E-03 ! regulation of interleukin-10 production GO:0032653 13 7 1,000 4,646E-04 9,154E-03 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 1,000 4,646E-04 9,08E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 4,646E-04 9,008E-03 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 1,000 4,646E-04 8,937E-03 GO:0002714|positive regulation of B cell mediated immunity, ! dopamine biosynthetic process GO:0042416 18 7 1,000 4,646E-04 8,867E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 4,646E-04 8,799E-03 ! positive regulation of catabolic process GO:0009896 72 32 2,000 4,732E-04 8,893E-03 ! phosphoinositide metabolic process GO:0030384 146 77 3,000 5,094E-04 9,499E-03 ! leukocyte chemotaxis GO:0030595 55 33 2,000 5,187E-04 9,601E-03 GO:0060326|cell chemotaxis, ! protein oligomerization GO:0051259 149 79 3,000 5,614E-04 0,01031149 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 5,67E-04 0,01033637 ! positive regulation of phosphorylation GO:0042327 149 81 3,000 6,171E-04 0,01116636 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 1,000 6,175E-04 0,01109304 ! regulation of cellular amine metabolic process GO:0033238 13 8 1,000 6,175E-04 0,01101207 ! ER overload response GO:0006983 13 8 1,000 6,175E-04 0,01093227 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 1,000 6,175E-04 0,01085362 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 6,175E-04 0,0107761 ! mast cell activation GO:0045576 14 8 1,000 6,175E-04 0,01069967 ! gas homeostasis GO:0033483 14 8 1,000 6,175E-04 0,01062432 ! regulation of respiratory burst GO:0060263 12 8 1,000 6,175E-04 0,01055002 ! B cell receptor signaling pathway GO:0050853 22 8 1,000 6,175E-04 0,01047676 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 6,175E-04 0,01040451 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 6,175E-04 0,01033324 ! placenta development GO:0001890 53 35 2,000 6,18E-04 0,01026975 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 6,765E-04 0,01116751 GO:0045937|positive regulation of phosphate metabolic process, ! tissue remodeling GO:0048771 78 37 2,000 7,285E-04 0,01194471 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 7,285E-04 0,01186508 ! regulation of microtubule-based process GO:0032886 86 37 2,000 7,285E-04 0,0117865 ! glycogen metabolic process GO:0005977 63 38 2,000 7,882E-04 0,01266838 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 7,915E-04 0,01263814 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 7,915E-04 0,01255607 ! regulation of glycolysis GO:0006110 20 9 1,000 7,915E-04 0,01247506 ! T cell selection GO:0045058 27 9 1,000 7,915E-04 0,0123951 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 7,915E-04 0,01231615 ! glucan metabolic process GO:0044042 64 39 2,000 8,509E-04 0,01315701 GO:0006073|cellular glucan metabolic process, ! glycerol ether metabolic process GO:0006662 57 40 2,000 9,167E-04 0,01408521 ! ossification GO:0001503 205 91 3,000 9,554E-04 0,01458837 ! regulation of hormone secretion GO:0046883 69 41 2,000 9,857E-04 0,01495626 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 9,857E-04 0,01486394 ! mesenchymal cell development GO:0014031 94 41 2,000 9,857E-04 0,01477275 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of developmental growth GO:0048638 16 10 1,000 9,863E-04 0,01469202 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 9,863E-04 0,01460298 ! glucan biosynthetic process GO:0009250 14 10 1,000 9,863E-04 0,01451501 GO:0005978|glycogen biosynthetic process, ! central nervous system neuron axonogenesis GO:0021955 23 10 1,000 9,863E-04 0,0144281 GO:0021952|central nervous system projection neuron axonogenesis, ! protein heterooligomerization GO:0051291 17 10 1,000 9,863E-04 0,01434221 ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 9,863E-04 0,01425735 ! positive regulation of phagocytosis GO:0050766 14 10 1,000 9,863E-04 0,01417348 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 1,000 9,863E-04 0,0140906 ! regulation of fat cell differentiation GO:0045598 18 10 1,000 9,863E-04 0,01400867 ! regulation of B cell differentiation GO:0045577 24 10 1,000 9,863E-04 0,0139277 ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 9,863E-04 0,01384766 ! induction of an organ GO:0001759 17 10 1,000 9,863E-04 0,01376853 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 9,863E-04 0,0136903 ! positive regulation of acute inflammatory response GO:0002675 18 10 1,000 9,863E-04 0,01361295 ! midbrain development GO:0030901 14 10 1,000 9,863E-04 0,01353647 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 9,863E-04 0,01346085 GO:0043470|regulation of carbohydrate catabolic process, ! bone development GO:0060348 206 92 3,000 9,952E-04 0,01350712 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,036E-03 0,0139847 ! organic ether metabolic process GO:0018904 59 42 2,000 1,058E-03 0,01419877 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 1,058E-03 0,01412118 ! regulation of leukocyte mediated immunity GO:0002703 84 42 2,000 1,058E-03 0,01404443 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,202E-03 0,01586885 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,202E-03 0,01578353 ! adult heart development GO:0007512 16 11 1,000 1,202E-03 0,01569913 ! negative regulation of ossification GO:0030279 27 11 1,000 1,202E-03 0,01561562 ! alpha-beta T cell activation GO:0046631 26 11 1,000 1,202E-03 0,015533 ! negative regulation of glucose import GO:0046325 18 11 1,000 1,202E-03 0,01545125 GO:0010829|negative regulation of glucose transport, ! regulation of embryonic development GO:0045995 35 11 1,000 1,202E-03 0,01537035 ! phagocytosis GO:0006909 105 44 2,000 1,212E-03 0,01541971 ! leukocyte differentiation GO:0002521 232 98 3,000 1,259E-03 0,01593068 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,379E-03 0,01737031 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 1,379E-03 0,01728123 ! leukocyte migration GO:0050900 75 46 2,000 1,379E-03 0,01719306 ! positive regulation of protein transport GO:0051222 80 46 2,000 1,379E-03 0,01710579 ! virus-host interaction GO:0019048 30 12 1,000 1,438E-03 0,0177368 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,438E-03 0,01764767 ! entry into host cell GO:0030260 34 12 1,000 1,438E-03 0,01755943 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 17 12 1,000 1,438E-03 0,01747207 ! histone acetylation GO:0016573 27 12 1,000 1,438E-03 0,01738558 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,438E-03 0,01729993 ! T cell homeostasis GO:0043029 28 12 1,000 1,438E-03 0,01721513 ! developmental induction GO:0031128 22 12 1,000 1,438E-03 0,01713115 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 1,438E-03 0,01704799 ! regulation of JNK cascade GO:0046328 104 47 2,000 1,468E-03 0,01732903 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,561E-03 0,01833161 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 2,000 1,561E-03 0,0182439 ! response to calcium ion GO:0051592 94 49 2,000 1,657E-03 0,01927409 ! protein homooligomerization GO:0051260 84 49 2,000 1,657E-03 0,01918274 ! organelle fusion GO:0048284 36 13 1,000 1,694E-03 0,01951632 ! monoamine transport GO:0015844 21 13 1,000 1,694E-03 0,01942469 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,694E-03 0,01933392 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cytokine production during immune response GO:0002718 25 13 1,000 1,694E-03 0,019244 ! nucleoside triphosphate catabolic process GO:0009143 22 13 1,000 1,694E-03 0,0191549 ! gland morphogenesis GO:0022612 31 13 1,000 1,694E-03 0,01906663 ! regulation of acute inflammatory response GO:0002673 24 13 1,000 1,694E-03 0,01897917 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 1,000 1,694E-03 0,01889251 ! regulation of cell projection organization GO:0031344 135 51 2,000 1,86E-03 0,02065163 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 1,000 1,97E-03 0,02177365 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 1,97E-03 0,02167557 ! regulation of calcium-mediated signaling GO:0050848 29 14 1,000 1,97E-03 0,02157837 ! positive regulation of protein polymerization GO:0032273 27 14 1,000 1,97E-03 0,02148204 ! positive regulation of growth GO:0045927 96 53 2,000 2,078E-03 0,02255753 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 2,000 2,078E-03 0,02245772 ! regulation of neuron apoptosis GO:0043523 117 53 2,000 2,078E-03 0,02235879 ! regulation of cell shape GO:0008360 142 54 2,000 2,192E-03 0,02348851 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,266E-03 0,02417016 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 2,266E-03 0,02406507 ! regulation of vasodilation GO:0042312 27 15 1,000 2,266E-03 0,0239609 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,266E-03 0,02385762 ! dopamine metabolic process GO:0042417 35 15 1,000 2,266E-03 0,02375522 ! lymphocyte homeostasis GO:0002260 33 15 1,000 2,266E-03 0,02365371 ! regulation of protein polymerization GO:0032271 117 55 2,000 2,311E-03 0,02402009 ! response to UV GO:0009411 120 55 2,000 2,311E-03 0,02391831 ! skeletal muscle fiber development GO:0048741 130 56 2,000 2,433E-03 0,02507839 ! regulation of DNA replication GO:0006275 105 56 2,000 2,433E-03 0,02497301 ! muscle fiber development GO:0048747 131 57 2,000 2,559E-03 0,02615922 ! nucleotide-excision repair GO:0006289 91 57 2,000 2,559E-03 0,02605022 ! regulation of intracellular transport GO:0032386 108 57 2,000 2,559E-03 0,02594213 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,581E-03 0,02605768 ! bone remodeling GO:0046849 28 16 1,000 2,581E-03 0,02595044 ! startle response GO:0001964 28 16 1,000 2,581E-03 0,02584409 ! fructose metabolic process GO:0006000 25 16 1,000 2,581E-03 0,0257386 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 1,000 2,581E-03 0,02563398 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 2,581E-03 0,02553019 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 2,581E-03 0,02542725 ! positive regulation of cell migration GO:0030335 137 58 2,000 2,689E-03 0,02638654 ! cellular polysaccharide metabolic process GO:0044264 93 58 2,000 2,689E-03 0,026281 ! establishment of organelle localization GO:0051656 122 59 2,000 2,824E-03 0,02748314 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 2,916E-03 0,02827176 ! regulation of survival gene product expression GO:0045884 38 17 1,000 2,916E-03 0,02816001 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 2,916E-03 0,02804914 GO:0031114|regulation of microtubule depolymerization, ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 1,000 2,916E-03 0,02793915 GO:0002712|regulation of B cell mediated immunity, ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 2,916E-03 0,02783001 ! viral reproductive process GO:0022415 132 62 2,000 3,251E-03 0,03090364 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 3,271E-03 0,03096929 ! positive regulation of anti-apoptosis GO:0045768 47 18 1,000 3,271E-03 0,03084972 ! positive regulation of proteolysis GO:0045862 36 18 1,000 3,271E-03 0,03073107 ! glutamine metabolic process GO:0006541 29 18 1,000 3,271E-03 0,03061332 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 1,000 3,271E-03 0,03049648 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 3,271E-03 0,03038052 ! mesoderm development GO:0007498 128 63 2,000 3,402E-03 0,03147921 ! neuron maturation GO:0042551 46 19 1,000 3,644E-03 0,03359351 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 3,644E-03 0,03346722 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 1,000 3,644E-03 0,03334188 ! positive regulation of cell motion GO:0051272 157 65 2,000 3,716E-03 0,03387326 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 3,879E-03 0,03523219 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 4,036E-03 0,03652087 ! protein amino acid acetylation GO:0006473 41 20 1,000 4,036E-03 0,03638611 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 4,036E-03 0,03625234 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 4,036E-03 0,03611954 ! regulation of glucose import GO:0046324 30 20 1,000 4,036E-03 0,03598772 GO:0010827|regulation of glucose transport, ! activation of MAPK activity GO:0000187 124 67 2,000 4,047E-03 0,03595431 ! myeloid cell differentiation GO:0030099 126 67 2,000 4,047E-03 0,03582404 ! regulation of cellular response to stress GO:0080135 142 68 2,000 4,219E-03 0,03721318 ! viral reproduction GO:0016032 142 68 2,000 4,219E-03 0,03707932 ! negative regulation of cell size GO:0045792 144 69 2,000 4,396E-03 0,03849242 ! lung development GO:0030324 165 69 2,000 4,396E-03 0,03835495 ! developmental maturation GO:0021700 128 69 2,000 4,396E-03 0,03821845 ! lipid phosphorylation GO:0046834 43 21 1,000 4,447E-03 0,03852726 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 4,447E-03 0,03839112 ! regulation of vasoconstriction GO:0019229 40 21 1,000 4,447E-03 0,03825594 ! positive regulation of inflammatory response GO:0050729 41 21 1,000 4,447E-03 0,03812171 ! leukotriene biosynthetic process GO:0019370 42 21 1,000 4,447E-03 0,03798842 GO:0043450|alkene biosynthetic process, ! activation of immune response GO:0002253 120 70 2,000 4,577E-03 0,03895999 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 4,762E-03 0,04039764 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 4,877E-03 0,04122487 ! microtubule-based transport GO:0010970 59 22 1,000 4,877E-03 0,04108271 ! inactivation of MAPK activity GO:0000188 45 22 1,000 4,877E-03 0,04094153 ! central nervous system neuron development GO:0021954 47 22 1,000 4,877E-03 0,04080132 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 1,000 4,877E-03 0,04066207 ! positive regulation of adaptive immune response GO:0002821 42 22 1,000 4,877E-03 0,04052376 ! positive regulation of B cell activation GO:0050871 42 22 1,000 4,877E-03 0,0403864 ! activation of JUN kinase activity GO:0007257 47 22 1,000 4,877E-03 0,04024995 ! respiratory tube development GO:0030323 171 72 2,000 4,952E-03 0,04073561 ! regulation of immune effector process GO:0002697 156 73 2,000 5,147E-03 0,04219279 ! positive regulation of DNA replication GO:0045740 44 23 1,000 5,325E-03 0,0435053 ! regulation of anti-apoptosis GO:0045767 62 23 1,000 5,325E-03 0,04336028 ! glycerol metabolic process GO:0006071 40 23 1,000 5,325E-03 0,04321623 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 1,000 5,325E-03 0,04307313 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 5,325E-03 0,04293097 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 5,325E-03 0,04278975 ! regulation of interleukin-6 production GO:0032675 31 23 1,000 5,325E-03 0,04264946 ! regulation of bone mineralization GO:0030500 54 23 1,000 5,325E-03 0,04251008 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 5,346E-03 0,04253916 ! respiratory system development GO:0060541 175 74 2,000 5,346E-03 0,04240105 ! organelle localization GO:0051640 155 74 2,000 5,346E-03 0,04226383 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 5,549E-03 0,04373148 ! central nervous system neuron differentiation GO:0021953 51 24 1,000 5,791E-03 0,04548725 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 5,791E-03 0,04534146 ! sex determination GO:0007530 48 24 1,000 5,791E-03 0,0451966 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 1,000 5,791E-03 0,04505266 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 1,000 5,791E-03 0,04490964 ! leukotriene metabolic process GO:0006691 47 24 1,000 5,791E-03 0,04476752 ! regulation of tumor necrosis factor production GO:0032680 37 24 1,000 5,791E-03 0,04462629 ! membrane depolarization GO:0051899 45 24 1,000 5,791E-03 0,04448596 ! regulation of vesicle-mediated transport GO:0060627 136 77 2,000 5,97E-03 0,04572097 ! regulation of catabolic process GO:0009894 173 77 2,000 5,97E-03 0,04557809 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 6,275E-03 0,04775358 ! leukocyte adhesion GO:0007159 55 25 1,000 6,275E-03 0,04760528 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 6,275E-03 0,04745789 ! regulation of biomineral formation GO:0070167 56 25 1,000 6,275E-03 0,04731142 ! leukocyte homeostasis GO:0001776 50 25 1,000 6,275E-03 0,04716584 ! cellular alkene metabolic process GO:0043449 48 25 1,000 6,275E-03 0,04702116 ! protein tetramerization GO:0051262 57 25 1,000 6,275E-03 0,04687737 ! initiation of viral infection GO:0019059 60 26 1,000 6,776E-03 0,05047176 ! molting cycle process GO:0022404 52 26 1,000 6,776E-03 0,05031835 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 6,776E-03 0,05016587 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 6,776E-03 0,05001431 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 6,776E-03 0,04986367 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 6,776E-03 0,04971393 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 6,776E-03 0,04956508 ! osteoblast differentiation GO:0001649 63 26 1,000 6,776E-03 0,04941713 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 6,776E-03 0,04927005 ! regulation of blood coagulation GO:0030193 46 26 1,000 6,776E-03 0,04912385 ! alditol metabolic process GO:0019400 44 26 1,000 6,776E-03 0,04897851 ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 6,776E-03 0,04883403 ! muscle cell differentiation GO:0042692 178 81 2,000 6,868E-03 0,04934793 ! response to hypoxia GO:0001666 178 81 2,000 6,868E-03 0,04920322 ! regulation of peptidase activity GO:0052547 150 82 2,000 7,104E-03 0,05074704 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 1,000 7,296E-03 0,05196389 ! embryonic pattern specification GO:0009880 49 27 1,000 7,296E-03 0,05181283 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 1,000 7,296E-03 0,05166265 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 7,296E-03 0,05151334 ! response to oxygen levels GO:0070482 183 83 2,000 7,345E-03 0,05171279 ! response to metal ion GO:0010038 158 84 2,000 7,591E-03 0,05328996 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 7,833E-03 0,05482837 ! protein amino acid acylation GO:0043543 59 28 1,000 7,833E-03 0,05467171 ! vesicle docking GO:0048278 55 28 1,000 7,833E-03 0,05451595 ! negative regulation of protein modification process GO:0031400 66 28 1,000 7,833E-03 0,05436108 ! base-excision repair GO:0006284 41 28 1,000 7,833E-03 0,05420708 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 7,833E-03 0,05405396 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 7,833E-03 0,05390169 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 7,833E-03 0,05375028 ! positive regulation of cell activation GO:0050867 161 86 2,000 8,097E-03 0,05541006 GO:0002696|positive regulation of leukocyte activation, ! nucleosome assembly GO:0006334 126 87 2,000 8,358E-03 0,05703189 ! regulation of protein transport GO:0051223 165 87 2,000 8,358E-03 0,05687302 GO:0070201|regulation of establishment of protein localization, ! catechol metabolic process GO:0009712 55 29 1,000 8,387E-03 0,05691323 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 8,387E-03 0,05675558 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 8,387E-03 0,05659879 ! somitogenesis GO:0001756 52 29 1,000 8,387E-03 0,05644287 ! chromatin assembly GO:0031497 128 88 2,000 8,623E-03 0,05787186 ! phenol metabolic process GO:0018958 56 30 1,000 8,958E-03 0,05995666 ! icosanoid biosynthetic process GO:0046456 60 30 1,000 8,958E-03 0,05979284 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 8,958E-03 0,05962992 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 8,958E-03 0,05946788 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 8,958E-03 0,05930672 ! regulation of B cell activation GO:0050864 55 30 1,000 8,958E-03 0,05914643 ! regulation of coagulation GO:0050818 52 30 1,000 8,958E-03 0,05898701 ! response to inorganic substance GO:0010035 173 90 2,000 9,168E-03 0,06020746 ! positive regulation of protein modification process GO:0031401 156 90 2,000 9,168E-03 0,06004604 ! defense response to bacterium GO:0042742 112 91 2,000 9,448E-03 0,06171428 ! response to heat GO:0009408 54 31 1,000 9,546E-03 0,06218913 ! protein-DNA complex assembly GO:0065004 134 92 2,000 9,733E-03 0,06323724 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 0,01002268 0,06494802 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 1,000 0,01015087 0,06560471 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 0,01015087 0,06543161 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01015087 0,06525942 ! mesoderm formation GO:0001707 73 32 1,000 0,01015087 0,06508814 ! BMP signaling pathway GO:0030509 71 32 1,000 0,01015087 0,06491775 ! hindbrain development GO:0030902 65 32 1,000 0,01015087 0,06474825 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 0,01015087 0,06457964 ! myeloid leukocyte activation GO:0002274 53 32 1,000 0,01015087 0,0644119 ! carbohydrate biosynthetic process GO:0016051 158 94 2,000 0,01031755 0,06529994 ! nucleosome organization GO:0034728 143 95 2,000 0,01061742 0,0670242 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 0,01061742 0,06685146 ! cholesterol homeostasis GO:0042632 60 33 1,000 0,0107723 0,06765226 GO:0055092|sterol homeostasis, ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 1,000 0,0107723 0,06747879 ! triglyceride metabolic process GO:0006641 46 33 1,000 0,0107723 0,06730621 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 0,01123223 0,07000084 ! regulation of protein localization GO:0032880 188 97 2,000 0,01123223 0,06982272 ! post-embryonic development GO:0009791 76 34 1,000 0,01141013 0,07074862 ! inner ear morphogenesis GO:0042472 51 34 1,000 0,01141013 0,07056951 ! cholesterol transport GO:0030301 62 34 1,000 0,01141013 0,07039131 ! formation of primary germ layer GO:0001704 76 34 1,000 0,01141013 0,070214 ! cell fate specification GO:0001708 56 34 1,000 0,01141013 0,07003758 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 0,01141013 0,06986205 ! adult locomotory behavior GO:0008344 62 34 1,000 0,01141013 0,0696874 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 0,01154718 0,07034856 ! membrane docking GO:0022406 69 35 1,000 0,01206421 0,07331556 ! positive regulation of endocytosis GO:0045807 56 35 1,000 0,01206421 0,07313364 ! mesoderm morphogenesis GO:0048332 80 35 1,000 0,01206421 0,07295261 ! sterol transport GO:0015918 63 35 1,000 0,01206421 0,07277248 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01206421 0,07259324 ! biogenic amine biosynthetic process GO:0042401 65 35 1,000 0,01206421 0,07241488 ! positive regulation of immune response GO:0050778 175 100 2,000 0,01219228 0,07300428 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 0,01273435 0,0760636 ! regulation of proteolysis GO:0030162 77 36 1,000 0,01273435 0,07587808 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,0134204 0,07977136 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01412218 0,08373907 ! neutral lipid metabolic process GO:0006638 54 38 1,000 0,01412218 0,08353631 GO:0006639|acylglycerol metabolic process, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 1,000 0,01483955 0,08756768 ! nucleotide catabolic process GO:0009166 70 39 1,000 0,01483955 0,08735668 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01483955 0,08714668 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 93 40 1,000 0,01557233 0,0912307 ! lipid homeostasis GO:0055088 75 40 1,000 0,01557233 0,09101245 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,01632036 0,09515669 ! ear morphogenesis GO:0042471 64 42 1,000 0,01708349 0,09936899 ! T cell differentiation GO:0030217 93 42 1,000 0,01708349 0,09913296 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,01708349 0,09889805 ! cytokinesis GO:0000910 84 42 1,000 0,01708349 0,09866424 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01786156 0,10291459 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,01786156 0,10267244 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,01786156 0,10243142 ! glucose transport GO:0015758 66 43 1,000 0,01786156 0,10219154 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,01786156 0,10195277 ! hormone-mediated signaling GO:0009755 84 43 1,000 0,01786156 0,10171512 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,01786156 0,10147857 ! segmentation GO:0035282 78 43 1,000 0,01786156 0,10124312 ! neuron migration GO:0001764 85 43 1,000 0,01786156 0,10100877 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,0186544 0,10524873 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,0186544 0,10500622 ! hexose transport GO:0008645 68 44 1,000 0,0186544 0,10476483 GO:0015749|monosaccharide transport, ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 0,01946187 0,10904894 ! polyol metabolic process GO:0019751 77 45 1,000 0,01946187 0,1087994 ! developmental growth GO:0048589 88 45 1,000 0,01946187 0,108551 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,0202838 0,11287771 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,0202838 0,11262117 ! polysaccharide biosynthetic process GO:0000271 79 46 1,000 0,0202838 0,11236579 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 1,000 0,0202838 0,11211157 ! cell growth GO:0016049 90 46 1,000 0,0202838 0,1118585 ! positive regulation of defense response GO:0031349 88 48 1,000 0,02197044 0,12088691 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,02197044 0,12061526 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02197044 0,12034482 ! icosanoid metabolic process GO:0006690 92 48 1,000 0,02197044 0,12007559 ! regulation of inflammatory response GO:0050727 84 48 1,000 0,02197044 0,11980757 ! regulation of adaptive immune response GO:0002819 92 48 1,000 0,02197044 0,11954073 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,02283485 0,12396788 ! JNK cascade GO:0007254 106 49 1,000 0,02283485 0,123693 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,02283485 0,12341935 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02354967 0,12700185 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02354967 0,12672211 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02354967 0,1264436 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02354967 0,12616631 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02354967 0,12589023 ! neuron fate determination GO:0048664 7 5 0,000 0,02354967 0,12561537 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02354967 0,12534169 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02354967 0,12506921 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02354967 0,12479791 ! polyol transport GO:0015791 12 5 0,000 0,02354967 0,12452779 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02354967 0,12425883 ! response to superoxide GO:0000303 10 5 0,000 0,02354967 0,12399103 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02354967 0,12372438 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02354967 0,12345888 GO:0045940|positive regulation of steroid metabolic process, ! tongue development GO:0043586 8 5 0,000 0,02354967 0,12319451 ! female meiosis GO:0007143 10 5 0,000 0,02354967 0,12293128 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02354967 0,12266916 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02354967 0,12240816 ! hypothalamus development GO:0021854 9 5 0,000 0,02354967 0,12214827 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02354967 0,12188949 ! cobalt ion transport GO:0006824 11 5 0,000 0,02354967 0,12163179 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02354967 0,12137518 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02354967 0,12111966 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02354967 0,1208652 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02354967 0,12061182 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02354967 0,12035949 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02354967 0,12010822 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02354967 0,11985799 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02354967 0,11960881 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02354967 0,11936066 ! transposition GO:0032196 9 5 0,000 0,02354967 0,11911353 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02354967 0,11886743 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02354967 0,11862234 ! negative chemotaxis GO:0050919 16 5 0,000 0,02354967 0,11837827 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02354967 0,11813519 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02354967 0,11789311 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02354967 0,11765202 ! behavioral response to pain GO:0048266 10 5 0,000 0,02354967 0,11741191 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02354967 0,11717278 ! Notch receptor processing GO:0007220 11 5 0,000 0,02354967 0,11693463 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02354967 0,11669744 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02354967 0,11646121 ! micturition GO:0060073 9 5 0,000 0,02354967 0,11622593 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02354967 0,11599161 ! copulation GO:0007620 9 5 0,000 0,02354967 0,11575822 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02354967 0,11552578 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02354967 0,11529426 ! bioluminescence GO:0008218 9 5 0,000 0,02354967 0,11506367 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02354967 0,11483401 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02354967 0,11460525 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02354967 0,11437741 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02354967 0,11415047 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02354967 0,11392443 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02354967 0,11369928 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02354967 0,11347502 ! grooming behavior GO:0007625 6 5 0,000 0,02354967 0,11325165 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02354967 0,11302915 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02354967 0,11280752 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02354967 0,11258677 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02354967 0,11236687 ! response to protozoan GO:0001562 13 5 0,000 0,02354967 0,11214783 ! lymph vessel development GO:0001945 10 5 0,000 0,02354967 0,11192964 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02354967 0,11171231 ! endochondral ossification GO:0001958 17 5 0,000 0,02354967 0,11149581 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02354967 0,11128015 ! single strand break repair GO:0000012 8 5 0,000 0,02354967 0,11106532 ! parathyroid gland development GO:0060017 14 5 0,000 0,02354967 0,11085132 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02354967 0,11063815 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02354967 0,11042579 ! cytokine secretion GO:0050663 15 5 0,000 0,02354967 0,11021425 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02354967 0,11000351 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02354967 0,10979358 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02354967 0,10958445 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02354967 0,10937612 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02354967 0,10916857 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02354967 0,10896181 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02354967 0,10875584 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02354967 0,10855064 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02354967 0,10834621 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02354967 0,10814255 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02354967 0,10793966 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02354967 0,10773752 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02354967 0,10753614 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02354967 0,10733552 ! valine metabolic process GO:0006573 12 5 0,000 0,02354967 0,10713564 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02354967 0,1069365 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02354967 0,1067381 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02354967 0,10654044 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02354967 0,10634351 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02354967 0,1061473 ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02354967 0,10595182 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02354967 0,10575705 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02354967 0,105563 ! muscle cell migration GO:0014812 8 5 0,000 0,02354967 0,10536967 ! mitochondrial fission GO:0000266 8 5 0,000 0,02354967 0,10517703 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02354967 0,1049851 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02354967 0,10479387 ! mRNA transcription GO:0009299 10 5 0,000 0,02354967 0,10460334 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02354967 0,1044135 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02354967 0,10422434 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02354967 0,10403587 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02354967 0,10384808 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02354967 0,10366097 ! monocyte activation GO:0042117 10 5 0,000 0,02354967 0,10347453 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02354967 0,10328876 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02354967 0,10310365 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02354967 0,10291921 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02354967 0,10273542 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02354967 0,10255229 ! forebrain neuron development GO:0021884 13 5 0,000 0,02354967 0,10236982 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02354967 0,10218799 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02354967 0,1020068 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02354967 0,10182626 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02354967 0,10164636 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02354967 0,10146709 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02354967 0,10128845 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02354967 0,10111043 ! lipid glycosylation GO:0030259 7 5 0,000 0,02354967 0,10093305 ! nucleobase transport GO:0015851 6 5 0,000 0,02354967 0,10075628 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02354967 0,10058014 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02354967 0,1004046 ! basic amino acid transport GO:0015802 12 5 0,000 0,02354967 0,10022968 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02354967 0,10005537 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02354967 0,09988166 ! actin nucleation GO:0045010 11 5 0,000 0,02354967 0,09970856 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02354967 0,09953605 ! depurination GO:0045007 5 5 0,000 0,02354967 0,09936414 ! depyrimidination GO:0045008 10 5 0,000 0,02354967 0,09919282 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02354967 0,0990221 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02354967 0,09885195 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02354967 0,0986824 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02354967 0,09851342 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02354967 0,09834502 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02354967 0,0981772 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02354967 0,09800994 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02354967 0,09784326 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02354967 0,09767714 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02354967 0,09751159 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02354967 0,09734659 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02354967 0,09718216 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02354967 0,09701828 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02354967 0,09685494 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02354967 0,09669216 ! response to arsenic GO:0046685 11 5 0,000 0,02354967 0,09652993 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02354967 0,09636824 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02354967 0,09620709 GO:0002448|mast cell mediated immunity, ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02354967 0,09604647 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02354967 0,0958864 ! response to mercury ion GO:0046689 8 5 0,000 0,02354967 0,09572685 ! response to cadmium ion GO:0046686 7 5 0,000 0,02354967 0,09556784 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02354967 0,09540935 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02354967 0,09525139 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02354967 0,09509395 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02354967 0,09493703 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02354967 0,09478062 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02354967 0,09462473 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02354967 0,09446936 ! decidualization GO:0046697 11 5 0,000 0,02354967 0,09431449 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02354967 0,09416013 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02354967 0,09400627 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02354967 0,09385292 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02354967 0,09370006 ! embryonic cleavage GO:0040016 6 5 0,000 0,02354967 0,0935477 ! peroxisome fission GO:0016559 5 5 0,000 0,02354967 0,09339584 ! histone demethylation GO:0016577 13 5 0,000 0,02354967 0,09324447 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02354967 0,09309359 ! mitotic recombination GO:0006312 9 5 0,000 0,02354967 0,09294319 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02354967 0,09279329 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02354967 0,09264386 ! metaphase plate congression GO:0051310 7 5 0,000 0,02354967 0,09249492 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02354967 0,09234645 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02354967 0,09219846 ! enteric nervous system development GO:0048484 8 5 0,000 0,02354967 0,09205094 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02354967 0,09190389 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02354967 0,09175732 GO:0031295|T cell costimulation, ! muscle cell proliferation GO:0033002 12 5 0,000 0,02354967 0,09161121 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02354967 0,09146556 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02354967 0,09132038 ! B cell homeostasis GO:0001782 13 5 0,000 0,02354967 0,09117565 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02354967 0,09103139 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02354967 0,09088758 ! metaphase GO:0051323 11 5 0,000 0,02354967 0,09074422 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02354967 0,09060132 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02354967 0,09045886 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02354967 0,09031686 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02354967 0,09017529 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02354967 0,09003417 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02354967 0,0898935 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02354967 0,08975326 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02354967 0,08961345 ! response to redox state GO:0051775 6 5 0,000 0,02354967 0,08947409 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02354967 0,08933515 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02354967 0,08919665 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02354967 0,08905857 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02354967 0,08892092 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02354967 0,0887837 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02354967 0,0886469 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02354967 0,08851052 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02354967 0,08837456 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02354967 0,08823901 ! striatum development GO:0021756 14 5 0,000 0,02354967 0,08810389 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02354967 0,08796917 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02354967 0,08783487 ! glial cell migration GO:0008347 10 5 0,000 0,02354967 0,08770097 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02354967 0,08756748 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02354967 0,0874344 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02354967 0,08730173 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02354967 0,08716945 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02354967 0,08703758 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02354967 0,0869061 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02354967 0,08677502 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02354967 0,08664433 ! neuroprotection GO:0043526 8 5 0,000 0,02354967 0,08651404 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02354967 0,08638414 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02354967 0,08625463 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02354967 0,0861255 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02354967 0,08599677 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02354967 0,08586841 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02354967 0,08574044 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02354967 0,08561285 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02354967 0,08548564 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02354967 0,08535881 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02354967 0,08523235 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02354967 0,08510627 ! spindle assembly GO:0051225 6 5 0,000 0,02354967 0,08498056 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02354967 0,08485522 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02354967 0,08473025 ! protein palmitoylation GO:0018345 12 5 0,000 0,02354967 0,08460564 ! drug metabolic process GO:0017144 7 5 0,000 0,02354967 0,08448141 ! stem cell division GO:0017145 11 5 0,000 0,02354967 0,08435753 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02354967 0,08423402 ! organ regeneration GO:0031100 7 5 0,000 0,02354967 0,08411087 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02354967 0,08398808 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02354967 0,08386565 ! induction of apoptosis by extracellular signals GO:0008624 99 50 1,000 0,02371312 0,08432482 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,02371312 0,08420225 GO:0019724|B cell mediated immunity, ! positive regulation of cytokine production GO:0001819 94 50 1,000 0,02371312 0,08408005 ! viral infectious cycle GO:0019058 104 51 1,000 0,02460509 0,0871163 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,02460509 0,08699022 ! response to temperature stimulus GO:0009266 84 51 1,000 0,02460509 0,08686452 ! positive regulation of binding GO:0051099 88 52 1,000 0,02551063 0,0899314 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,02551063 0,08980182 ! unsaturated fatty acid metabolic process GO:0033559 98 52 1,000 0,02551063 0,08967261 ! histone modification GO:0016570 104 52 1,000 0,02551063 0,08954377 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 1,000 0,02551063 0,0894153 ! inner ear development GO:0048839 89 53 1,000 0,02642957 0,0925035 ! vesicle organization GO:0016050 127 53 1,000 0,02642957 0,09237116 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,02642957 0,09223921 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,02736178 0,09535639 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 1,000 0,02736178 0,09522056 ! regulation of muscle contraction GO:0006937 94 54 1,000 0,02736178 0,09508511 ! membrane fusion GO:0006944 122 54 1,000 0,02736178 0,09495004 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,02736178 0,09481536 ! covalent chromatin modification GO:0016569 115 54 1,000 0,02736178 0,09468106 ! glutamine family amino acid metabolic process GO:0009064 85 54 1,000 0,02736178 0,09454714 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02819302 0,09728185 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02819302 0,09714464 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02819302 0,09700781 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02819302 0,09687137 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02819302 0,09673532 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02819302 0,09659965 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02819302 0,09646435 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02819302 0,09632944 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02819302 0,0961949 ! response to oxygen radical GO:0000305 11 6 0,000 0,02819302 0,09606074 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02819302 0,09592695 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02819302 0,09579353 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02819302 0,09566048 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02819302 0,09552781 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02819302 0,0953955 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02819302 0,09526355 ! forebrain regionalization GO:0021871 9 6 0,000 0,02819302 0,09513197 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02819302 0,09500076 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02819302 0,0948699 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02819302 0,09473941 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02819302 0,09460927 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02819302 0,09447949 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02819302 0,09435007 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02819302 0,094221 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02819302 0,09409228 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02819302 0,09396391 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02819302 0,0938359 ! malate metabolic process GO:0006108 13 6 0,000 0,02819302 0,09370823 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02819302 0,09358091 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02819302 0,09345393 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02819302 0,0933273 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02819302 0,09320101 ! protein refolding GO:0042026 15 6 0,000 0,02819302 0,09307506 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02819302 0,09294946 ! opsonization GO:0008228 8 6 0,000 0,02819302 0,09282419 ! mating behavior GO:0007617 7 6 0,000 0,02819302 0,09269926 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02819302 0,09257466 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02819302 0,0924504 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02819302 0,09232647 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02819302 0,09220287 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02819302 0,09207961 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02819302 0,09195667 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02819302 0,09183406 ! toxin metabolic process GO:0009404 11 6 0,000 0,02819302 0,09171178 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02819302 0,09158982 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02819302 0,09146819 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02819302 0,09134688 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02819302 0,09122589 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02819302 0,09110522 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02819302 0,09098487 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02819302 0,09086484 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02819302 0,09074512 ! thymic T cell selection GO:0045061 16 6 0,000 0,02819302 0,09062572 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02819302 0,09050663 ! protein lipoylation GO:0009249 10 6 0,000 0,02819302 0,09038786 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02819302 0,09026939 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02819302 0,09015124 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02819302 0,0900334 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02819302 0,08991586 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02819302 0,08979863 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02819302 0,0896817 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02819302 0,08956508 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02819302 0,08944876 ! hyperosmotic response GO:0006972 10 6 0,000 0,02819302 0,08933275 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02819302 0,08921703 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02819302 0,08910161 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02819302 0,0889865 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02819302 0,08887167 ! urea metabolic process GO:0019627 7 6 0,000 0,02819302 0,08875715 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02819302 0,08864292 ! neutrophil activation GO:0042119 7 6 0,000 0,02819302 0,08852898 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02819302 0,08841534 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02819302 0,08830198 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02819302 0,08818892 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02819302 0,08807615 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02819302 0,08796366 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02819302 0,08785146 ! neuron apoptosis GO:0051402 15 6 0,000 0,02819302 0,08773955 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02819302 0,08762792 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02819302 0,08751658 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02819302 0,08740552 ! carnitine transport GO:0015879 10 6 0,000 0,02819302 0,08729474 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02819302 0,08718424 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02819302 0,08707402 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02819302 0,08696408 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02819302 0,08685441 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02819302 0,08674502 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02819302 0,08663591 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02819302 0,08652707 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02819302 0,0864185 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02819302 0,08631021 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02819302 0,08620219 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02819302 0,08609443 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02819302 0,08598695 ! response to UV-C GO:0010225 14 6 0,000 0,02819302 0,08587974 ! astrocyte development GO:0014002 16 6 0,000 0,02819302 0,08577279 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02819302 0,0856661 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02819302 0,08555969 ! interaction with symbiont GO:0051702 14 6 0,000 0,02819302 0,08545353 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02819302 0,08534764 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02819302 0,08524201 ! response to copper ion GO:0046688 10 6 0,000 0,02819302 0,08513665 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02819302 0,08503154 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02819302 0,08492669 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02819302 0,0848221 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02819302 0,08471777 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02819302 0,08461369 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02819302 0,08450987 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02819302 0,08440631 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02819302 0,084303 ! Schwann cell development GO:0014044 15 6 0,000 0,02819302 0,08419994 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02819302 0,08409713 ! response to pheromone GO:0019236 6 6 0,000 0,02819302 0,08399457 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02819302 0,08389226 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02819302 0,0837902 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02819302 0,08368839 ! subpallium development GO:0021544 15 6 0,000 0,02819302 0,08358683 ! neural tube patterning GO:0021532 8 6 0,000 0,02819302 0,08348551 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02819302 0,08338444 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02819302 0,08328361 ! G2 phase GO:0051319 16 6 0,000 0,02819302 0,08318303 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02819302 0,08308269 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02819302 0,08298259 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02819302 0,08288273 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02819302 0,08278311 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02819302 0,08268373 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02819302 0,08258459 ! receptor internalization GO:0031623 11 6 0,000 0,02819302 0,08248569 ! plasminogen activation GO:0031639 9 6 0,000 0,02819302 0,08238702 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02819302 0,08228859 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02819302 0,08219039 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02819302 0,08209243 ! protein deubiquitination GO:0016579 16 6 0,000 0,02819302 0,0819947 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02819302 0,0818972 ! protein destabilization GO:0031648 9 6 0,000 0,02819302 0,08179994 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02819302 0,0817029 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02819302 0,0816061 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02819302 0,08150952 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02819302 0,08141318 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02819302 0,08131706 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02819302 0,08122116 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02819302 0,0811255 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02819302 0,08103006 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02819302 0,08093484 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02819302 0,08083984 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02819302 0,08074507 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02819302 0,08065052 ! neural plate development GO:0001840 9 6 0,000 0,02819302 0,0805562 ! catecholamine transport GO:0051937 9 6 0,000 0,02819302 0,08046209 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02819302 0,0803682 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02819302 0,08027453 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02819302 0,08018108 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02819302 0,08008785 ! maternal placenta development GO:0001893 12 6 0,000 0,02819302 0,07999483 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02819302 0,07990203 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02819302 0,07980944 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02819302 0,07971707 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02819302 0,07962491 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02819302 0,07953296 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02819302 0,07944123 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,02830711 0,07967082 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,02830711 0,07957914 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,02830711 0,07948767 ! cell maturation GO:0048469 107 55 1,000 0,02830711 0,0793964 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,02926541 0,08199014 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,02926541 0,08189623 ! RNA elongation GO:0006354 90 56 1,000 0,02926541 0,08180252 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,03023655 0,08442045 ! heart morphogenesis GO:0003007 105 57 1,000 0,03023655 0,08432408 ! regulation of actin filament length GO:0030832 118 58 1,000 0,03122038 0,0869685 ! gastrulation GO:0007369 122 58 1,000 0,03122038 0,08686945 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,03122038 0,08677062 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 1,000 0,03122038 0,08667202 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,03122038 0,08657364 ! maintenance of location GO:0051235 124 58 1,000 0,03122038 0,08647549 ! tRNA transcription GO:0009304 17 7 0,000 0,03281442 0,09078781 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03281442 0,0906851 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03281442 0,09058264 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03281442 0,0904804 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03281442 0,09037839 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03281442 0,09027661 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03281442 0,09017506 ! sleep GO:0030431 16 7 0,000 0,03281442 0,09007374 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03281442 0,08997265 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03281442 0,08987179 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03281442 0,08977114 ! prostate gland development GO:0030850 14 7 0,000 0,03281442 0,08967073 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03281442 0,08957054 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03281442 0,08947057 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03281442 0,08937083 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03281442 0,08927131 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03281442 0,089172 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03281442 0,08907292 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03281442 0,08897406 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03281442 0,08887542 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03281442 0,088777 ! glycolipid transport GO:0046836 11 7 0,000 0,03281442 0,0886788 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03281442 0,08858081 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03281442 0,08848304 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03281442 0,08838548 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03281442 0,08828814 ! mRNA stabilization GO:0048255 18 7 0,000 0,03281442 0,08819101 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03281442 0,0880941 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03281442 0,0879974 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03281442 0,08790091 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03281442 0,08780464 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03281442 0,08770857 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03281442 0,08761271 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03281442 0,08751707 ! lipoprotein transport GO:0042953 14 7 0,000 0,03281442 0,08742163 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03281442 0,0873264 ! rhythmic behavior GO:0007622 17 7 0,000 0,03281442 0,08723137 ! neuron remodeling GO:0016322 16 7 0,000 0,03281442 0,08713656 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03281442 0,08704195 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03281442 0,08694754 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03281442 0,08685334 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03281442 0,08675934 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03281442 0,08666555 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03281442 0,08657196 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03281442 0,08647857 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03281442 0,08638538 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03281442 0,08629239 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03281442 0,0861996 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03281442 0,08610702 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03281442 0,08601463 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03281442 0,08592244 ! spinal cord patterning GO:0021511 14 7 0,000 0,03281442 0,08583044 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03281442 0,08573864 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03281442 0,08564704 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03281442 0,08555564 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03281442 0,08546443 ! adrenal gland development GO:0030325 17 7 0,000 0,03281442 0,08537341 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03281442 0,08528259 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03281442 0,08519196 ! ovulation GO:0030728 10 7 0,000 0,03281442 0,08510152 ! adenohypophysis development GO:0021984 11 7 0,000 0,03281442 0,08501127 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03281442 0,08492122 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03281442 0,08483136 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03281442 0,08474168 ! microtubule nucleation GO:0007020 21 7 0,000 0,03281442 0,0846522 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03281442 0,0845629 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03281442 0,0844738 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03281442 0,08438488 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03281442 0,08429614 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03281442 0,0842076 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03281442 0,08411924 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03281442 0,08403106 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03281442 0,08394307 ! galactose metabolic process GO:0006012 13 7 0,000 0,03281442 0,08385526 ! response to dietary excess GO:0002021 8 7 0,000 0,03281442 0,08376764 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03281442 0,0836802 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03281442 0,08359294 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03281442 0,08350587 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03281442 0,08341897 ! organ growth GO:0035265 15 7 0,000 0,03281442 0,08333226 ! nucleoside transport GO:0015858 11 7 0,000 0,03281442 0,08324572 ! nucleoside salvage GO:0043174 11 7 0,000 0,03281442 0,08315937 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03281442 0,08307319 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03281442 0,0829872 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03281442 0,08290138 ! parturition GO:0007567 16 7 0,000 0,03281442 0,08281574 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03281442 0,08273027 ! rRNA modification GO:0000154 14 7 0,000 0,03281442 0,08264498 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03281442 0,08255987 ! spindle checkpoint GO:0031577 16 7 0,000 0,03281442 0,08247493 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03281442 0,08239017 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03281442 0,08230558 ! monocyte differentiation GO:0030224 16 7 0,000 0,03281442 0,08222116 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03281442 0,08213692 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03281442 0,08205285 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03281442 0,08196895 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03281442 0,08188522 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03281442 0,08180167 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03281442 0,08171828 ! fibrinolysis GO:0042730 11 7 0,000 0,03281442 0,08163506 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03281442 0,08155202 ! eating behavior GO:0042755 8 7 0,000 0,03281442 0,08146914 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03281442 0,08138643 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03281442 0,08130389 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03281442 0,08122151 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03281442 0,0811393 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03281442 0,08105726 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03281442 0,08097539 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03281442 0,08089368 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03281442 0,08081213 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03281442 0,08073075 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03281442 0,08064953 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03281442 0,08056847 ! histone ubiquitination GO:0016574 9 7 0,000 0,03281442 0,08048758 ! regulation of meiosis GO:0040020 12 7 0,000 0,03281442 0,08040685 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03281442 0,08032628 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03281442 0,08024588 ! regulation of lipid transport GO:0032368 14 7 0,000 0,03281442 0,08016563 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03281442 0,08008555 ! transcription termination GO:0006353 14 7 0,000 0,03281442 0,08000562 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03281442 0,07992585 ! anaphase GO:0051322 18 7 0,000 0,03281442 0,07984625 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03281442 0,0797668 ! axonal fasciculation GO:0007413 19 7 0,000 0,03281442 0,07968751 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03281442 0,07960837 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03281442 0,0795294 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03281442 0,07945058 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03281442 0,07937191 ! diuresis GO:0030146 12 7 0,000 0,03281442 0,0792934 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03281442 0,07921505 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03281442 0,07913685 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03281442 0,07905881 ! antibiotic transport GO:0042891 9 7 0,000 0,03281442 0,07898092 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03281442 0,07890318 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03281442 0,0788256 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03281442 0,07874817 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03281442 0,07867089 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03281442 0,07859376 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03281442 0,07851678 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03281442 0,07843995 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03281442 0,07836328 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03281442 0,07828675 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03281442 0,07821037 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03281442 0,07813414 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03281442 0,07805806 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03281442 0,07798213 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03281442 0,07790635 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03281442 0,07783071 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03281442 0,07775522 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03281442 0,07767988 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03281442 0,07760468 ! muscle adaptation GO:0043500 13 7 0,000 0,03281442 0,07752963 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03281442 0,07745472 ! retina homeostasis GO:0001895 12 7 0,000 0,03281442 0,07737995 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03281442 0,07730533 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03281442 0,07723086 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03281442 0,07715653 ! lipid modification GO:0030258 112 60 1,000 0,03322553 0,07804806 ! DNA catabolic process GO:0006308 94 60 1,000 0,03322553 0,07797308 ! regulation of endocytosis GO:0030100 104 60 1,000 0,03322553 0,07789825 ! adult behavior GO:0030534 104 60 1,000 0,03322553 0,07782357 ! regulation of cellular component size GO:0032535 125 61 1,000 0,03424659 0,08013833 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 0,03424659 0,08006164 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,03527977 0,08239817 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,03738199 0,08722465 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03741398 0,08721598 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03741398 0,08713283 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03741398 0,08704985 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03741398 0,08696703 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03741398 0,08688436 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03741398 0,08680185 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03741398 0,08671949 ! male meiosis GO:0007140 9 8 0,000 0,03741398 0,08663729 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03741398 0,08655525 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 14 8 0,000 0,03741398 0,08647336 ! response to zinc ion GO:0010043 12 8 0,000 0,03741398 0,08639163 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03741398 0,08631005 ! oligopeptide transport GO:0006857 16 8 0,000 0,03741398 0,08622863 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03741398 0,08614735 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03741398 0,08606624 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03741398 0,08598527 ! signal peptide processing GO:0006465 12 8 0,000 0,03741398 0,08590446 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03741398 0,0858238 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03741398 0,08574329 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03741398 0,08566293 ! succinate metabolic process GO:0006105 17 8 0,000 0,03741398 0,08558272 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03741398 0,08550266 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03741398 0,08542275 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03741398 0,08534299 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03741398 0,08526338 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03741398 0,08518392 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03741398 0,0851046 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03741398 0,08502544 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03741398 0,08494642 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03741398 0,08486754 ! reflex GO:0060004 17 8 0,000 0,03741398 0,08478882 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03741398 0,08471023 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03741398 0,0846318 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03741398 0,08455351 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03741398 0,08447536 ! pigment granule organization GO:0048753 17 8 0,000 0,03741398 0,08439736 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03741398 0,08431951 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03741398 0,08424179 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03741398 0,08416422 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03741398 0,08408679 ! histidine catabolic process GO:0006548 10 8 0,000 0,03741398 0,08400951 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03741398 0,08393236 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03741398 0,08385536 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03741398 0,0837785 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03741398 0,08370178 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03741398 0,0836252 ! melanin metabolic process GO:0006582 17 8 0,000 0,03741398 0,08354876 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03741398 0,08347246 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03741398 0,0833963 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03741398 0,08332028 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03741398 0,08324439 ! macrophage activation GO:0042116 13 8 0,000 0,03741398 0,08316865 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03741398 0,08309304 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03741398 0,08301757 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03741398 0,08294224 ! purine salvage GO:0043101 12 8 0,000 0,03741398 0,08286704 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03741398 0,08279198 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03741398 0,08271705 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03741398 0,08264226 ! osteoblast development GO:0002076 17 8 0,000 0,03741398 0,08256761 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03741398 0,08249309 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03741398 0,0824187 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03741398 0,08234445 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03741398 0,08227034 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03741398 0,08219635 ! response to UV-B GO:0010224 17 8 0,000 0,03741398 0,0821225 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03741398 0,08204878 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03741398 0,0819752 ! intermediate filament organization GO:0045109 12 8 0,000 0,03741398 0,08190174 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03741398 0,08182842 ! cellular extravasation GO:0045123 13 8 0,000 0,03741398 0,08175523 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03741398 0,08168217 ! response to antibiotic GO:0046677 11 8 0,000 0,03741398 0,08160924 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03741398 0,08153643 ! DNA topological change GO:0006265 12 8 0,000 0,03741398 0,08146376 ! response to tropane GO:0014073 15 8 0,000 0,03741398 0,08139122 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,03741398 0,08131881 ! melanosome transport GO:0032402 13 8 0,000 0,03741398 0,08124653 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03741398 0,08117437 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03741398 0,08110235 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03741398 0,08103045 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03741398 0,08095867 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03741398 0,08088703 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03741398 0,08081551 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03741398 0,08074412 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03741398 0,08067285 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03741398 0,08060171 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03741398 0,0805307 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03741398 0,08045981 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03741398 0,08038904 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03741398 0,0803184 ! response to tumor cell GO:0002347 16 8 0,000 0,03741398 0,08024789 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03741398 0,08017749 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03741398 0,08010722 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03741398 0,08003708 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03741398 0,07996705 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03741398 0,07989715 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03741398 0,07982737 ! hormone catabolic process GO:0042447 17 8 0,000 0,03741398 0,07975772 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03741398 0,07968818 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03741398 0,07961877 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03741398 0,07954947 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03741398 0,0794803 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03741398 0,07941125 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03741398 0,07934231 ! adult feeding behavior GO:0008343 10 8 0,000 0,03741398 0,0792735 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03741398 0,0792048 ! ATP catabolic process GO:0006200 11 8 0,000 0,03741398 0,07913623 ! blastocyst growth GO:0001832 19 8 0,000 0,03741398 0,07906777 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03741398 0,07899943 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03741398 0,07893121 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03741398 0,07886311 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03741398 0,07879512 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03741398 0,07872726 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03741398 0,0786595 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03741398 0,07859187 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03741398 0,07852435 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03741398 0,07845695 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03741398 0,07838966 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03741398 0,07832249 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03741398 0,07825543 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03741398 0,07818849 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03741398 0,07812166 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03741398 0,07805495 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03741398 0,07798835 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03741398 0,07792186 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,03845076 0,08001295 ! ear development GO:0043583 114 66 1,000 0,03953111 0,08219107 ! regulation of cytokine biosynthetic process GO:0042035 108 66 1,000 0,03953111 0,08212118 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,04062292 0,08431759 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,04062292 0,08424601 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 139 67 1,000 0,04062292 0,08417456 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,04172606 0,08638709 ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,04172606 0,08631394 ! regulation of lipase activity GO:0060191 137 68 1,000 0,04172606 0,08624092 ! adaptive immune response GO:0002250 126 68 1,000 0,04172606 0,08616802 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! axon extension GO:0048675 16 9 0,000 0,04199179 0,08664352 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04199179 0,08657041 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04199179 0,08649741 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04199179 0,08642454 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04199179 0,08635179 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04199179 0,08627917 ! reproductive behavior GO:0019098 22 9 0,000 0,04199179 0,08620667 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04199179 0,08613428 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04199179 0,08606202 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04199179 0,08598988 ! UTP metabolic process GO:0046051 10 9 0,000 0,04199179 0,08591787 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04199179 0,08584597 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,04199179 0,08577419 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04199179 0,08570253 ! artery development GO:0060840 25 9 0,000 0,04199179 0,085631 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04199179 0,08555958 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04199179 0,08548828 ! equilibrioception GO:0050957 20 9 0,000 0,04199179 0,0854171 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04199179 0,08534603 ! chemosensory behavior GO:0007635 21 9 0,000 0,04199179 0,08527509 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04199179 0,08520426 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04199179 0,08513355 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04199179 0,08506296 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04199179 0,08499249 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04199179 0,08492213 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04199179 0,08485189 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04199179 0,08478176 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04199179 0,08471175 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04199179 0,08464186 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04199179 0,08457208 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04199179 0,08450242 ! protein targeting to ER GO:0045047 25 9 0,000 0,04199179 0,08443287 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04199179 0,08436343 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04199179 0,08429411 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04199179 0,0842249 ! glycine catabolic process GO:0006546 15 9 0,000 0,04199179 0,08415581 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04199179 0,08408683 ! endosome organization GO:0007032 20 9 0,000 0,04199179 0,08401796 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04199179 0,08394921 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04199179 0,08388057 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04199179 0,08381204 ! mannose metabolic process GO:0006013 13 9 0,000 0,04199179 0,08374362 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04199179 0,08367531 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04199179 0,08360712 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04199179 0,08353903 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04199179 0,08347106 ! receptor clustering GO:0043113 20 9 0,000 0,04199179 0,0834032 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04199179 0,08333544 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04199179 0,0832678 ! retinol metabolic process GO:0042572 20 9 0,000 0,04199179 0,08320027 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04199179 0,08313285 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04199179 0,08306553 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04199179 0,08299833 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04199179 0,08293123 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04199179 0,08286424 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04199179 0,08279736 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04199179 0,08273059 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04199179 0,08266393 ! response to amine stimulus GO:0014075 13 9 0,000 0,04199179 0,08259737 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04199179 0,08253092 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04199179 0,08246458 ! erythrocyte development GO:0048821 17 9 0,000 0,04199179 0,08239834 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04199179 0,08233221 ! renal water homeostasis GO:0003091 15 9 0,000 0,04199179 0,08226618 ! postreplication repair GO:0006301 25 9 0,000 0,04199179 0,08220027 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04199179 0,08213445 ! icosanoid secretion GO:0032309 15 9 0,000 0,04199179 0,08206875 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04199179 0,08200314 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04199179 0,08193765 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04199179 0,08187225 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04199179 0,08180696 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04199179 0,08174178 ! sterol catabolic process GO:0016127 14 9 0,000 0,04199179 0,0816767 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04199179 0,08161172 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04199179 0,08154685 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04199179 0,08148207 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04199179 0,08141741 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04199179 0,08135284 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04199179 0,08128838 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04199179 0,08122402 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04199179 0,08115976 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04199179 0,0810956 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04199179 0,08103154 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04199179 0,08096759 ! purine base metabolic process GO:0006144 25 9 0,000 0,04199179 0,08090373 ! pigment granule transport GO:0051904 17 9 0,000 0,04199179 0,08083998 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,04199179 0,08077632 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04199179 0,08071277 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04199179 0,08064932 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04199179 0,08058596 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04199179 0,08052271 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04199179 0,08045955 ! mitochondrion localization GO:0051646 18 9 0,000 0,04199179 0,0803965 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 0,04284039 0,08195699 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,04284039 0,08189286 ! single fertilization GO:0007338 83 69 1,000 0,04284039 0,08182883 ! negative regulation of kinase activity GO:0033673 145 70 1,000 0,04396579 0,08391282 ! cell redox homeostasis GO:0045454 114 70 1,000 0,04396579 0,08384732 ! germ cell development GO:0007281 133 70 1,000 0,04396579 0,08378191 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,04510212 0,08588033 ! appendage morphogenesis GO:0035107 150 72 1,000 0,04624925 0,08799605 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 1,000 0,04624925 0,08792757 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04654795 0,08842663 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,04654795 0,08835792 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04654795 0,08828932 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04654795 0,08822083 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04654795 0,08815244 ! associative learning GO:0008306 21 10 0,000 0,04654795 0,08808416 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,04654795 0,08801598 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04654795 0,08794791 ! phosphate transport GO:0006817 24 10 0,000 0,04654795 0,08787994 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04654795 0,08781208 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,04654795 0,08774433 ! CTP metabolic process GO:0046036 11 10 0,000 0,04654795 0,08767668 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04654795 0,08760913 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04654795 0,08754168 ! GTP metabolic process GO:0046039 11 10 0,000 0,04654795 0,08747434 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04654795 0,08740711 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04654795 0,08733998 ! social behavior GO:0035176 29 10 0,000 0,04654795 0,08727295 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04654795 0,08720602 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04654795 0,08713919 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04654795 0,08707247 ! androgen metabolic process GO:0008209 17 10 0,000 0,04654795 0,08700585 ! phospholipid efflux GO:0033700 19 10 0,000 0,04654795 0,08693933 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04654795 0,08687292 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04654795 0,0868066 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04654795 0,08674039 ! lung alveolus development GO:0048286 26 10 0,000 0,04654795 0,08667427 ! pathogenesis GO:0009405 17 10 0,000 0,04654795 0,08660826 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04654795 0,08654235 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,04654795 0,08647654 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04654795 0,08641083 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04654795 0,08634521 ! endoderm development GO:0007492 18 10 0,000 0,04654795 0,0862797 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04654795 0,08621429 ! arginine catabolic process GO:0006527 17 10 0,000 0,04654795 0,08614898 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04654795 0,08608376 ! proline metabolic process GO:0006560 13 10 0,000 0,04654795 0,08601864 ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04654795 0,08595363 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04654795 0,08588871 ! V(D)J recombination GO:0033151 34 10 0,000 0,04654795 0,08582389 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04654795 0,08575916 ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04654795 0,08569453 ! B cell proliferation GO:0042100 19 10 0,000 0,04654795 0,08563001 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04654795 0,08556557 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04654795 0,08550124 ! multicellular organism growth GO:0035264 19 10 0,000 0,04654795 0,085437 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04654795 0,08537286 ! ruffle organization GO:0031529 17 10 0,000 0,04654795 0,08530881 ! epithelial cell development GO:0002064 21 10 0,000 0,04654795 0,08524486 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04654795 0,08518101 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04654795 0,08511725 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04654795 0,08505359 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04654795 0,08499002 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04654795 0,08492655 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04654795 0,08486317 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,04654795 0,08479989 ! motor axon guidance GO:0008045 22 10 0,000 0,04654795 0,0847367 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04654795 0,0846736 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04654795 0,0846106 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04654795 0,08454769 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04654795 0,08448488 ! segment specification GO:0007379 15 10 0,000 0,04654795 0,08442216 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04654795 0,08435953 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04654795 0,084297 ! response to dsRNA GO:0043331 23 10 0,000 0,04654795 0,08423455 ! DNA ligation GO:0006266 18 10 0,000 0,04654795 0,0841722 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04654795 0,08410995 ! melanosome localization GO:0032400 16 10 0,000 0,04654795 0,08404778 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04654795 0,08398571 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04654795 0,08392373 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04654795 0,08386183 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04654795 0,08380004 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04654795 0,08373833 ! protein sumoylation GO:0016925 17 10 0,000 0,04654795 0,08367671 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04654795 0,08361518 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04654795 0,08355375 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04654795 0,0834924 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04654795 0,08343114 ! salivary gland development GO:0007431 28 10 0,000 0,04654795 0,08336998 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04654795 0,0833089 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! musculoskeletal movement GO:0050881 16 10 0,000 0,04654795 0,08324791 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04654795 0,08318701 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04654795 0,0831262 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04654795 0,08306548 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04654795 0,08300485 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04654795 0,08294431 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04654795 0,08288385 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04654795 0,08282349 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04654795 0,08276321 ! detection of calcium ion GO:0005513 24 10 0,000 0,04654795 0,08270302 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04654795 0,08264291 ! blastocyst formation GO:0001825 18 10 0,000 0,04654795 0,0825829 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04654795 0,08252297 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04654795 0,08246312 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04654795 0,08240337 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04654795 0,0823437 ! response to nicotine GO:0035094 20 10 0,000 0,04654795 0,08228412 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04654795 0,08222462 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04654795 0,08216521 ! appendage development GO:0048736 151 73 1,000 0,04740707 0,08362128 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 0,04857544 0,08562035 ! negative regulation of transferase activity GO:0051348 155 74 1,000 0,04857544 0,08555862 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,04975424 0,08757177 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,04975424 0,08750872 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,05094335 0,08953568 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,05094335 0,08947131 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05108258 0,08965139 ! respiratory burst GO:0045730 17 11 0,000 0,05108258 0,08958703 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05108258 0,08952277 ! neuron fate specification GO:0048665 18 11 0,000 0,05108258 0,08945859 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05108258 0,08939451 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05108258 0,08933052 ! thyroid gland development GO:0030878 26 11 0,000 0,05108258 0,08926662 ! synapsis GO:0007129 14 11 0,000 0,05108258 0,08920282 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05108258 0,0891391 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05108258 0,08907547 ! response to pain GO:0048265 27 11 0,000 0,05108258 0,08901194 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05108258 0,0889485 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05108258 0,08888514 ! blood vessel remodeling GO:0001974 30 11 0,000 0,05108258 0,08882188 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05108258 0,0887587 ! bone resorption GO:0045453 16 11 0,000 0,05108258 0,08869562 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05108258 0,08863263 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05108258 0,08856972 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05108258 0,08850691 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05108258 0,08844418 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05108258 0,08838154 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05108258 0,08831899 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05108258 0,08825653 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05108258 0,08819416 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05108258 0,08813188 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05108258 0,08806968 ! UV protection GO:0009650 20 11 0,000 0,05108258 0,08800757 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,05108258 0,08794555 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05108258 0,08788362 ! macroautophagy GO:0016236 19 11 0,000 0,05108258 0,08782177 ! temperature homeostasis GO:0001659 18 11 0,000 0,05108258 0,08776001 ! behavioral fear response GO:0001662 27 11 0,000 0,05108258 0,08769834 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05108258 0,08763675 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05108258 0,08757526 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05108258 0,08751384 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05108258 0,08745251 ! regulation of organ growth GO:0046620 14 11 0,000 0,05108258 0,08739127 ! pigment granule localization GO:0051875 20 11 0,000 0,05108258 0,08733012 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05108258 0,08726905 ! vasoconstriction GO:0042310 20 11 0,000 0,05108258 0,08720806 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05108258 0,08714716 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05108258 0,08708635 ! embryonic axis specification GO:0000578 19 11 0,000 0,05108258 0,08702562 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05108258 0,08696497 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05108258 0,08690441 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05108258 0,08684394 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05108258 0,08678355 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05108258 0,08672324 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05108258 0,08666301 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05108258 0,08660287 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05108258 0,08654281 ! prophase GO:0051324 17 11 0,000 0,05108258 0,08648284 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05108258 0,08642295 ! nucleosome positioning GO:0016584 15 11 0,000 0,05108258 0,08636314 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05108258 0,08630342 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05108258 0,08624377 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05108258 0,08618421 ! apical protein localization GO:0045176 18 11 0,000 0,05108258 0,08612473 ! acid secretion GO:0046717 20 11 0,000 0,05108258 0,08606534 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05108258 0,08600602 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05108258 0,08594679 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05108258 0,08588764 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05108258 0,08582857 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05108258 0,08576958 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05108258 0,08571067 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05108258 0,08565185 ! cholesterol efflux GO:0033344 21 11 0,000 0,05108258 0,0855931 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05108258 0,08553443 ! oocyte development GO:0048599 20 11 0,000 0,05108258 0,08547585 ! germ cell migration GO:0008354 26 11 0,000 0,05108258 0,08541734 ! embryonic gut development GO:0048566 19 11 0,000 0,05108258 0,08535892 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05108258 0,08530057 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05108258 0,08524231 ! activation of innate immune response GO:0002218 16 11 0,000 0,05108258 0,08518412 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05108258 0,08512602 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05108258 0,08506799 ! lysogeny GO:0030069 22 11 0,000 0,05108258 0,08501004 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05108258 0,08495217 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05108258 0,08489438 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05108258 0,08483667 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,05214263 0,08653835 ! antigen processing and presentation GO:0019882 117 78 1,000 0,05335198 0,08848533 ! fertilization GO:0009566 99 78 1,000 0,05335198 0,08842529 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,05335198 0,08836535 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,05457126 0,09032357 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05559576 0,09195698 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05559576 0,09189476 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05559576 0,09183263 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,05559576 0,09177058 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,05559576 0,09170861 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05559576 0,09164673 ! protein complex disassembly GO:0043241 28 12 0,000 0,05559576 0,09158493 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05559576 0,09152322 ! hippocampus development GO:0021766 29 12 0,000 0,05559576 0,09146158 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05559576 0,09140004 ! T cell proliferation GO:0042098 32 12 0,000 0,05559576 0,09133857 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05559576 0,09127719 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05559576 0,09121588 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05559576 0,09115467 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05559576 0,09109353 ! drug transport GO:0015893 16 12 0,000 0,05559576 0,09103247 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05559576 0,0909715 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,05559576 0,09091061 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,05559576 0,0908498 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05559576 0,09078907 ! focal adhesion formation GO:0048041 37 12 0,000 0,05559576 0,09072843 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05559576 0,09066786 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05559576 0,09060737 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05559576 0,09054697 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05559576 0,09048664 ! lipid digestion GO:0044241 21 12 0,000 0,05559576 0,0904264 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05559576 0,09036624 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05559576 0,09030615 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05559576 0,09024615 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05559576 0,09018622 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05559576 0,09012638 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05559576 0,09006661 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05559576 0,09000693 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05559576 0,08994732 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05559576 0,08988779 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05559576 0,08982834 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05559576 0,08976897 ! cranial nerve development GO:0021545 23 12 0,000 0,05559576 0,08970968 ! fucose catabolic process GO:0019317 25 12 0,000 0,05559576 0,08965046 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,05559576 0,08959133 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05559576 0,08953227 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05559576 0,08947329 ! zymogen activation GO:0031638 18 12 0,000 0,05559576 0,08941439 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05559576 0,08935556 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05559576 0,08929681 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,05559576 0,08923814 ! oocyte differentiation GO:0009994 21 12 0,000 0,05559576 0,08917955 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05559576 0,08912103 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05559576 0,08906259 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,05559576 0,08900423 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,05559576 0,08894594 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05559576 0,08888773 ! defense response to fungus GO:0050832 15 12 0,000 0,05559576 0,0888296 ! embryonic placenta development GO:0001892 21 12 0,000 0,05559576 0,08877154 ! lamellipodium assembly GO:0030032 24 12 0,000 0,05559576 0,08871355 ! response to cold GO:0009409 17 12 0,000 0,05559576 0,08865565 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05559576 0,08859782 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05559576 0,08854006 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,05580036 0,088808 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,05580036 0,08875018 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,05703916 0,09066146 ! protein import into nucleus GO:0006606 174 82 1,000 0,05828753 0,09258546 ! nuclear import GO:0051170 177 83 1,000 0,05954537 0,09452198 ! inorganic anion transport GO:0015698 156 83 1,000 0,05954537 0,0944606 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06008761 0,09525895 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06008761 0,09519717 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06008761 0,09513547 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06008761 0,09507386 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06008761 0,09501232 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06008761 0,09495086 ! peroxisomal transport GO:0043574 28 13 0,000 0,06008761 0,09488949 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06008761 0,09482819 ! cartilage condensation GO:0001502 22 13 0,000 0,06008761 0,09476697 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06008761 0,09470583 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06008761 0,09464477 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06008761 0,09458379 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06008761 0,09452288 ! endocrine pancreas development GO:0031018 25 13 0,000 0,06008761 0,09446206 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06008761 0,09440131 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06008761 0,09434064 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06008761 0,09428005 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06008761 0,09421953 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06008761 0,0941591 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06008761 0,09409874 ! methionine metabolic process GO:0006555 31 13 0,000 0,06008761 0,09403846 ! plasma membrane organization GO:0007009 27 13 0,000 0,06008761 0,09397826 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06008761 0,09391813 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06008761 0,09385808 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06008761 0,09379811 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06008761 0,09373821 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,06008761 0,09367839 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06008761 0,09361864 ! exocrine system development GO:0035272 34 13 0,000 0,06008761 0,09355898 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06008761 0,09349939 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06008761 0,09343987 GO:0006509|membrane protein ectodomain proteolysis, ! L-glutamate transport GO:0015813 30 13 0,000 0,06008761 0,09338043 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06008761 0,09332107 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06008761 0,09326178 ! protein homotetramerization GO:0051289 24 13 0,000 0,06008761 0,09320256 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06008761 0,09314342 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06008761 0,09308436 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06008761 0,09302537 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06008761 0,09296646 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06008761 0,09290762 ! histone methylation GO:0016571 29 13 0,000 0,06008761 0,09284885 ! chromatin silencing GO:0006342 29 13 0,000 0,06008761 0,09279016 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06008761 0,09273154 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06008761 0,092673 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06008761 0,09261453 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06008761 0,09255614 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06008761 0,09249782 ! spleen development GO:0048536 24 13 0,000 0,06008761 0,09243957 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,06008761 0,09238139 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06008761 0,09232329 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06008761 0,09226526 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06008761 0,09220731 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06008761 0,09214943 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06008761 0,09209162 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06008761 0,09203388 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06008761 0,09197621 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06008761 0,09191862 ! insulin secretion GO:0030073 24 13 0,000 0,06008761 0,0918611 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,06008761 0,09180365 ! acrosome reaction GO:0007340 19 13 0,000 0,06008761 0,09174627 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06008761 0,09168897 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06008761 0,09163173 ! T cell activation GO:0042110 189 84 1,000 0,06081255 0,09267938 ! negative regulation of transport GO:0051051 164 85 1,000 0,06208895 0,09456565 ! negative regulation of growth GO:0045926 168 85 1,000 0,06208895 0,09450673 ! rRNA transcription GO:0009303 28 14 0,000 0,06455822 0,09820407 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,06455822 0,09814296 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,06455822 0,09808192 ! water transport GO:0006833 21 14 0,000 0,06455822 0,09802096 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,06455822 0,09796008 ! non-recombinational repair GO:0000726 29 14 0,000 0,06455822 0,09789928 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,06455822 0,09783854 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,06455822 0,09777789 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,06455822 0,09771731 ! RNA polyadenylation GO:0043631 32 14 0,000 0,06455822 0,0976568 ! palate development GO:0060021 32 14 0,000 0,06455822 0,09759637 ! regulated secretory pathway GO:0045055 24 14 0,000 0,06455822 0,09753601 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,06455822 0,09747573 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,06455822 0,09741552 ! arginine metabolic process GO:0006525 21 14 0,000 0,06455822 0,09735539 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,06455822 0,09729533 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,06455822 0,09723535 ! regulation of heart rate GO:0002027 25 14 0,000 0,06455822 0,09717544 ! fear response GO:0042596 34 14 0,000 0,06455822 0,0971156 ! organic alcohol transport GO:0015850 29 14 0,000 0,06455822 0,09705584 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,06455822 0,09699615 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,06455822 0,09693653 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06455822 0,09687699 ! neutral amino acid transport GO:0015804 28 14 0,000 0,06455822 0,09681752 ! bone mineralization GO:0030282 18 14 0,000 0,06455822 0,09675812 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,06455822 0,09669879 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,06455822 0,09663954 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,06455822 0,09658036 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,06455822 0,09652126 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,06455822 0,09646222 ! regulation of cellular pH GO:0030641 27 14 0,000 0,06455822 0,09640326 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,06455822 0,09634437 ! ribosome assembly GO:0042255 18 14 0,000 0,06455822 0,09628555 ! cerebellum development GO:0021549 23 14 0,000 0,06455822 0,0962268 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,06455822 0,09616813 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,06455822 0,09610953 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,06455822 0,09605099 ! response to gamma radiation GO:0010332 30 14 0,000 0,06455822 0,09599253 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,06455822 0,09593414 ! NADP metabolic process GO:0006739 24 14 0,000 0,06455822 0,09587582 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,06455822 0,09581758 ! oxygen transport GO:0015671 22 14 0,000 0,06455822 0,0957594 ! male genitalia development GO:0030539 26 14 0,000 0,06455822 0,09570129 ! regulation of RNA stability GO:0043487 33 14 0,000 0,06455822 0,09564326 ! regulation of axon extension GO:0030516 43 14 0,000 0,06455822 0,09558529 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,06455822 0,0955274 ! mitochondrion organization GO:0007005 159 87 1,000 0,06466899 0,09563337 ! alcohol catabolic process GO:0046164 142 87 1,000 0,06466899 0,09557552 ! amine biosynthetic process GO:0009309 146 88 1,000 0,06597239 0,09744289 ! regulation of DNA binding GO:0051101 167 89 1,000 0,06728456 0,09932096 ! protein localization in nucleus GO:0034504 192 89 1,000 0,06728456 0,09926098 ! regulation of neurological system process GO:0031644 175 89 1,000 0,06728456 0,09920108 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06900769 0,10168021 ! lactation GO:0007595 30 15 0,000 0,06900769 0,10161892 ! reproductive cellular process GO:0048610 22 15 0,000 0,06900769 0,1015577 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06900769 0,10149656 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,06900769 0,10143549 ! superoxide anion generation GO:0042554 22 15 0,000 0,06900769 0,1013745 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,06900769 0,10131357 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,06900769 0,10125272 ! copper ion transport GO:0006825 22 15 0,000 0,06900769 0,10119195 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,06900769 0,10113125 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,06900769 0,10107062 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,06900769 0,10101006 ! sulfate transport GO:0008272 27 15 0,000 0,06900769 0,10094957 ! response to cAMP GO:0051591 25 15 0,000 0,06900769 0,10088916 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,06900769 0,10082882 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,06900769 0,10076855 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,06900769 0,10070836 ! response to hexose stimulus GO:0009746 25 15 0,000 0,06900769 0,10064823 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,06900769 0,10058818 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,06900769 0,1005282 ! vesicle coating GO:0006901 38 15 0,000 0,06900769 0,10046829 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,06900769 0,10040845 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,06900769 0,10034868 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,06900769 0,10028899 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,06900769 0,10022936 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,06900769 0,10016981 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,06900769 0,10011032 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,06900769 0,10005091 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,06900769 0,09999157 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,06900769 0,0999323 ! histone deacetylation GO:0016575 24 15 0,000 0,06900769 0,0998731 ! water homeostasis GO:0030104 28 15 0,000 0,06900769 0,09981396 ! cofactor transport GO:0051181 30 15 0,000 0,06900769 0,0997549 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06900769 0,09969591 ! muscle maintenance GO:0046716 26 15 0,000 0,06900769 0,09963699 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,06900769 0,09957814 ! intestinal absorption GO:0050892 31 15 0,000 0,06900769 0,09951935 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,06900769 0,09946064 ! heme biosynthetic process GO:0006783 33 15 0,000 0,06900769 0,099402 ! cell killing GO:0001906 32 15 0,000 0,06900769 0,09934342 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,06900769 0,09928492 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,06900769 0,09922648 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,06900769 0,09916811 ! actin filament polymerization GO:0030041 27 15 0,000 0,06900769 0,09910981 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,06900769 0,09905158 ! gland development GO:0048732 220 91 1,000 0,06993478 0,10032335 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,0712726 0,10218249 ! amine transport GO:0015837 181 93 1,000 0,07261875 0,10405138 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,07343612 0,10516087 ! positive regulation of cell size GO:0045793 29 16 0,000 0,07343612 0,10509926 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,07343612 0,10503773 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,07343612 0,10497627 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,07343612 0,10491488 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,07343612 0,10485356 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,07343612 0,10479231 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07343612 0,10473114 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,07343612 0,10467004 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,07343612 0,104609 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,07343612 0,10454804 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,07343612 0,10448715 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,07343612 0,10442633 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,07343612 0,10436559 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,07343612 0,10430491 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,07343612 0,1042443 ! protein polyubiquitination GO:0000209 41 16 0,000 0,07343612 0,10418376 ! glutamate metabolic process GO:0006536 25 16 0,000 0,07343612 0,1041233 ! pituitary gland development GO:0021983 30 16 0,000 0,07343612 0,1040629 ! response to osmotic stress GO:0006970 27 16 0,000 0,07343612 0,10400258 ! lysosomal transport GO:0007041 31 16 0,000 0,07343612 0,10394232 ! L-amino acid transport GO:0015807 33 16 0,000 0,07343612 0,10388213 ! stem cell development GO:0048864 46 16 0,000 0,07343612 0,10382202 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07343612 0,10376197 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07343612 0,10370199 ! intermediate filament-based process GO:0045103 36 16 0,000 0,07343612 0,10364208 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,07343612 0,10358224 ! negative regulation of immune response GO:0050777 38 16 0,000 0,07343612 0,10352247 ! axon cargo transport GO:0008088 46 16 0,000 0,07343612 0,10346277 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,07343612 0,10340314 ! DNA replication initiation GO:0006270 28 16 0,000 0,07343612 0,10334357 ! neuron recognition GO:0008038 40 16 0,000 0,07343612 0,10328408 ! mRNA splice site selection GO:0006376 44 16 0,000 0,07343612 0,10322465 ! tissue regeneration GO:0042246 27 16 0,000 0,07343612 0,10316529 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,07343612 0,103106 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,07343612 0,10304678 ! biomineral formation GO:0031214 22 16 0,000 0,07343612 0,10298762 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,07343612 0,10292854 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,07343612 0,10286952 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,07343612 0,10281057 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07343612 0,10275168 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,07343612 0,10269287 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,07343612 0,10263412 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,07343612 0,10257544 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,07343612 0,10251682 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07343612 0,10245828 ! peptide hormone processing GO:0016486 27 16 0,000 0,07343612 0,1023998 ! regulation of membrane potential GO:0042391 179 94 1,000 0,07397312 0,10308976 ! regulation of defense response GO:0031347 171 95 1,000 0,07533561 0,10492868 ! regulation of T cell activation GO:0050863 175 96 1,000 0,07670611 0,10677665 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,07784361 0,10829837 ! metencephalon development GO:0022037 32 17 0,000 0,07784361 0,10823673 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,07784361 0,10817516 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,07784361 0,10811367 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,07784361 0,10805224 ! signal complex assembly GO:0007172 47 17 0,000 0,07784361 0,10799088 ! endothelial cell migration GO:0043542 31 17 0,000 0,07784361 0,10792959 ! gene silencing by RNA GO:0031047 38 17 0,000 0,07784361 0,10786837 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,07784361 0,10780722 ! glial cell development GO:0021782 28 17 0,000 0,07784361 0,10774614 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,07784361 0,10768513 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,07784361 0,10762419 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,07784361 0,10756331 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,07784361 0,10750251 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,07784361 0,10744177 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,07784361 0,10738111 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,07784361 0,10732051 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,07784361 0,10725998 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,07784361 0,10719951 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,07784361 0,10713912 ! NAD metabolic process GO:0019674 33 17 0,000 0,07784361 0,10707879 ! membrane budding GO:0006900 42 17 0,000 0,07784361 0,10701854 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,07784361 0,10695835 ! regulation of protein binding GO:0043393 33 17 0,000 0,07784361 0,10689822 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,07784361 0,10683817 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,07784361 0,10677818 ! genitalia development GO:0048806 32 17 0,000 0,07784361 0,10671826 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,07784361 0,10665841 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,07784361 0,10659862 ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,07784361 0,1065389 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,07784361 0,10647925 ! steroid catabolic process GO:0006706 34 17 0,000 0,07784361 0,10641966 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,07784361 0,10636015 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,07784361 0,10630069 ! gas transport GO:0015669 26 17 0,000 0,07784361 0,10624131 ! organic cation transport GO:0015695 32 17 0,000 0,07784361 0,10618199 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,07784361 0,10612273 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,07784361 0,10606355 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,07808451 0,10633247 ! transcription initiation GO:0006352 171 97 1,000 0,07808451 0,10627323 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,08223026 0,1118533 ! limbic system development GO:0021761 40 18 0,000 0,08223026 0,11179105 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08223026 0,11172888 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,08223026 0,11166677 ! adult walking behavior GO:0007628 36 18 0,000 0,08223026 0,11160473 ! patterning of blood vessels GO:0001569 43 18 0,000 0,08223026 0,11154276 ! heart looping GO:0001947 34 18 0,000 0,08223026 0,11148087 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,08223026 0,11141903 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,08223026 0,11135727 ! centrosome cycle GO:0007098 26 18 0,000 0,08223026 0,11129558 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,08223026 0,11123395 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,08223026 0,1111724 ! glycine metabolic process GO:0006544 30 18 0,000 0,08223026 0,11111091 ! response to retinoic acid GO:0032526 31 18 0,000 0,08223026 0,11104949 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,08223026 0,11098813 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,08223026 0,11092685 ! DNA integration GO:0015074 32 18 0,000 0,08223026 0,11086563 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,08223026 0,11080448 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,08223026 0,1107434 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,08223026 0,11068238 ! neural crest cell migration GO:0001755 41 18 0,000 0,08223026 0,11062143 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,08223026 0,11056055 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,08223026 0,11049974 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,08223026 0,11043899 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,08223026 0,11037831 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,08223026 0,11031769 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,08223026 0,11025715 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,08223026 0,11019666 ! detection of bacterium GO:0016045 22 18 0,000 0,08223026 0,11013625 ! nerve development GO:0021675 34 18 0,000 0,08223026 0,1100759 ! defense response to virus GO:0051607 43 18 0,000 0,08223026 0,11001562 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,08223026 0,1099554 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,08659616 0,11572999 ! positive regulation of translation GO:0045727 31 19 0,000 0,08659616 0,11566671 ! negative regulation of defense response GO:0031348 27 19 0,000 0,08659616 0,11560351 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,08659616 0,11554037 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,08659616 0,1154773 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,08659616 0,11541431 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,08659616 0,11535137 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,08659616 0,11528851 ! inositol metabolic process GO:0006020 33 19 0,000 0,08659616 0,11522572 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08659616 0,11516299 ! memory GO:0007613 34 19 0,000 0,08659616 0,11510034 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,08659616 0,11503775 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,08659616 0,11497523 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,08659616 0,11491278 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,08659616 0,11485039 ! cerebral cortex development GO:0021987 40 19 0,000 0,08659616 0,11478807 ! pigmentation during development GO:0048066 42 19 0,000 0,08659616 0,11472583 ! response to vitamin A GO:0033189 32 19 0,000 0,08659616 0,11466364 ! heme metabolic process GO:0042168 40 19 0,000 0,08659616 0,11460153 ! neuromuscular junction development GO:0007528 43 19 0,000 0,08659616 0,11453948 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,08659616 0,1144775 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,08659616 0,11441559 ! response to fungus GO:0009620 26 19 0,000 0,08659616 0,11435374 ! peptide cross-linking GO:0018149 39 19 0,000 0,08659616 0,11429196 ! protein export from nucleus GO:0006611 40 19 0,000 0,08659616 0,11423025 ! heart process GO:0003015 32 19 0,000 0,08659616 0,1141686 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,08659616 0,11410702 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,08659616 0,11404551 ! visual learning GO:0008542 38 19 0,000 0,08659616 0,11398406 ! cellular pigmentation GO:0033059 37 19 0,000 0,08659616 0,11392268 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,08659616 0,11386137 ! vitamin transport GO:0051180 31 19 0,000 0,08659616 0,11380012 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,08659616 0,11373894 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,08659616 0,11367782 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,08659616 0,11361677 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,08659616 0,11355578 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,08659616 0,11349486 ! cilium assembly GO:0042384 38 19 0,000 0,08659616 0,11343401 ! peptide hormone secretion GO:0030072 32 19 0,000 0,08659616 0,11337322 ! protein secretion GO:0009306 45 20 0,000 0,09094142 0,11899833 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,09094142 0,11893463 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,09094142 0,11887099 ! positive regulation of ossification GO:0045778 50 20 0,000 0,09094142 0,11880742 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,09094142 0,11874393 ! skin development GO:0043588 42 20 0,000 0,09094142 0,11868049 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,09094142 0,11861713 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,09094142 0,11855383 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,09094142 0,1184906 ! response to vitamin GO:0033273 36 20 0,000 0,09094142 0,11842744 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,09094142 0,11836435 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,09094142 0,11830132 ! bile acid metabolic process GO:0008206 34 20 0,000 0,09094142 0,11823836 ! response to alkaloid GO:0043279 38 20 0,000 0,09094142 0,11817547 ! retinoid metabolic process GO:0001523 34 20 0,000 0,09094142 0,11811264 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,09094142 0,11804989 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,09094142 0,11798719 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,09094142 0,11792457 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,09094142 0,11786201 ! body fluid secretion GO:0007589 33 20 0,000 0,09094142 0,11779951 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,09094142 0,11773709 ! peptide secretion GO:0002790 38 20 0,000 0,09094142 0,11767473 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,09094142 0,11761243 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,09094142 0,1175502 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,09094142 0,11748804 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,09094142 0,11742594 ! cell-cell junction organization GO:0045216 43 20 0,000 0,09094142 0,11736391 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,09094142 0,11730195 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,09094142 0,11724004 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,09094142 0,11717821 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,09094142 0,11711644 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,09094142 0,11705473 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,09094142 0,11699309 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,09094142 0,11693152 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,09094142 0,11687001 ! negative regulation of translation GO:0017148 32 20 0,000 0,09094142 0,11680856 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,09094142 0,11674718 ! regulation of cell killing GO:0031341 46 21 0,000 0,09526613 0,12223484 ! hormone secretion GO:0046879 39 21 0,000 0,09526613 0,12217068 ! cAMP metabolic process GO:0046058 41 21 0,000 0,09526613 0,12210658 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,09526613 0,12204255 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,09526613 0,12197859 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,09526613 0,12191469 ! ovarian follicle development GO:0001541 39 21 0,000 0,09526613 0,12185086 ! smooth muscle contraction GO:0006939 48 21 0,000 0,09526613 0,1217871 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,09526613 0,1217234 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,09526613 0,12165977 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,09526613 0,12159621 ! plasma membrane fusion GO:0045026 33 21 0,000 0,09526613 0,12153271 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,09526613 0,12146928 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,09526613 0,12140592 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,09526613 0,12134262 ! diencephalon development GO:0021536 36 21 0,000 0,09526613 0,12127939 ! collagen fibril organization GO:0030199 62 21 0,000 0,09526613 0,12121622 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,09526613 0,12115312 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,09526613 0,12109009 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,09526613 0,12102712 ! collagen catabolic process GO:0030574 29 21 0,000 0,09526613 0,12096421 ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,09526613 0,12090137 ! sperm-egg recognition GO:0035036 23 21 0,000 0,09526613 0,1208386 ! actin filament-based movement GO:0030048 47 21 0,000 0,09526613 0,12077589 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,09526613 0,12071325 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,09957038 0,12610183 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,09957038 0,1260365 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,09957038 0,12597123 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,09957038 0,12590602 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,09957038 0,12584089 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,09957038 0,12577582 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,09957038 0,12571082 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,09957038 0,12564589 ! cellular response to starvation GO:0009267 37 22 0,000 0,09957038 0,12558102 ! vacuolar transport GO:0007034 41 22 0,000 0,09957038 0,12551622 ! fucose metabolic process GO:0006004 44 22 0,000 0,09957038 0,12545149 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,09957038 0,12538682 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,09957038 0,12532222 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,09957038 0,12525769 ! ureteric bud development GO:0001657 50 22 0,000 0,09957038 0,12519323 ! cell aging GO:0007569 48 22 0,000 0,09957038 0,12512883 ! stem cell differentiation GO:0048863 57 22 0,000 0,09957038 0,12506449 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,09957038 0,12500022 ! cytolysis GO:0019835 27 22 0,000 0,09957038 0,12493602 ! renal system process GO:0003014 42 22 0,000 0,09957038 0,12487189 ! vasodilation GO:0042311 40 22 0,000 0,09957038 0,12480782 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,09957038 0,12474381 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,09957038 0,12467988 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,09957038 0,124616 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,09957038 0,1245522 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,09957038 0,12448845 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,09957038 0,12442478 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,09957038 0,12436116 ! sarcomere organization GO:0045214 32 22 0,000 0,09957038 0,12429762 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,09957038 0,12423414 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,09957038 0,12417072 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,09957038 0,12410737 ! gut development GO:0048565 44 22 0,000 0,09957038 0,12404408 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,09957038 0,12398085 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,09957038 0,1239177 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,09957038 0,1238546 ! protein stabilization GO:0050821 41 22 0,000 0,09957038 0,12379157 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,10385428 0,12905188 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,10385428 0,12898627 ! gluconeogenesis GO:0006094 38 23 0,000 0,10385428 0,12892073 ! viral genome replication GO:0019079 44 23 0,000 0,10385428 0,12885526 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,10385428 0,12878985 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,10385428 0,1287245 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,10385428 0,12865923 ! regeneration GO:0031099 42 23 0,000 0,10385428 0,12859402 ! axis specification GO:0009798 43 23 0,000 0,10385428 0,12852887 ! visual behavior GO:0007632 46 23 0,000 0,10385428 0,1284638 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,10385428 0,12839878 ! response to ethanol GO:0045471 47 23 0,000 0,10385428 0,12833384 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,10385428 0,12826896 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,10385428 0,12820414 ! peroxisome organization GO:0007031 43 23 0,000 0,10385428 0,12813939 ! lysosome organization GO:0007040 47 23 0,000 0,10385428 0,12807471 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,10385428 0,12801009 ! vesicle targeting GO:0006903 49 23 0,000 0,10385428 0,12794554 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,10385428 0,12788105 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,10385428 0,12781662 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,10385428 0,12775227 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,10385428 0,12768797 ! DNA modification GO:0006304 36 23 0,000 0,10385428 0,12762374 ! fatty acid transport GO:0015908 47 23 0,000 0,10385428 0,12755958 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,10385428 0,12749548 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,10385428 0,12743144 ! hormone transport GO:0009914 41 23 0,000 0,10385428 0,12736747 ! cell-cell recognition GO:0009988 28 23 0,000 0,10385428 0,12730356 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,10385428 0,12723972 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,10385428 0,12717594 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,10385428 0,12711222 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,10811791 0,13226443 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,10811791 0,13219823 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,10811791 0,1321321 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,10811791 0,13206603 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,10811791 0,13200003 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,10811791 0,1319341 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,10811791 0,13186823 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,10811791 0,13180243 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,10811791 0,13173669 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,10811791 0,13167102 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,10811791 0,13160541 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,10811791 0,13153987 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,10811791 0,1314744 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,10811791 0,13140899 ! pallium development GO:0021543 56 24 0,000 0,10811791 0,13134364 ! oogenesis GO:0048477 44 24 0,000 0,10811791 0,13127836 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,10811791 0,13121315 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,10811791 0,131148 ! platelet activation GO:0030168 41 24 0,000 0,10811791 0,13108291 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,10811791 0,13101789 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,10811791 0,13095293 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,10811791 0,13088804 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,10811791 0,13082321 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,10811791 0,13075845 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,10811791 0,13069375 ! regulation of amine transport GO:0051952 41 24 0,000 0,10811791 0,13062911 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,11236138 0,13568901 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,11236138 0,13562197 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,11236138 0,13555499 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,11236138 0,13548809 ! phototransduction GO:0007602 37 25 0,000 0,11236138 0,13542124 ! keratinization GO:0031424 37 25 0,000 0,11236138 0,13535447 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,11236138 0,13528776 ! vacuole organization GO:0007033 49 25 0,000 0,11236138 0,13522111 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,11236138 0,13515454 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,11236138 0,13508802 ! receptor metabolic process GO:0043112 53 25 0,000 0,11236138 0,13502157 ! chromosome condensation GO:0030261 48 25 0,000 0,11236138 0,13495519 ! regulation of behavior GO:0050795 48 25 0,000 0,11236138 0,13488888 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,11236138 0,13482262 ! immunoglobulin production GO:0002377 62 25 0,000 0,11236138 0,13475644 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,11236138 0,13469031 ! liver development GO:0001889 55 25 0,000 0,11236138 0,13462426 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,11658478 0,13961599 ! myelination GO:0042552 50 26 0,000 0,11658478 0,13954759 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,11658478 0,13947925 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,11658478 0,13941098 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,11658478 0,13934277 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,11658478 0,13927463 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,11658478 0,13920656 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,11658478 0,13913856 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,11658478 0,13907062 ! digestive system process GO:0022600 49 26 0,000 0,11658478 0,13900275 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,11658478 0,13893494 ! neural crest cell development GO:0014032 59 26 0,000 0,11658478 0,1388672 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,11658478 0,13879953 ! negative regulation of cell development GO:0010721 83 26 0,000 0,11658478 0,13873192 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,11658478 0,13866437 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,11658478 0,1385969 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,11658478 0,13852949 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,11658478 0,13846214 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,11658478 0,13839486 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,11658478 0,13832765 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,11658478 0,1382605 ! blastocyst development GO:0001824 50 26 0,000 0,11658478 0,13819341 ! telomere organization GO:0032200 46 26 0,000 0,11658478 0,13812639 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,11658478 0,13805944 ! neural tube closure GO:0001843 58 26 0,000 0,11658478 0,13799255 GO:0060606|tube closure, ! regulation of multi-organism process GO:0043900 45 26 0,000 0,11658478 0,13792573 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,12078821 0,14282942 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,12078821 0,14276032 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,12078821 0,14269129 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,12078821 0,14262232 ! iron ion transport GO:0006826 65 27 0,000 0,12078821 0,14255342 ! superoxide metabolic process GO:0006801 41 27 0,000 0,12078821 0,14248459 ! tube lumen formation GO:0035148 59 27 0,000 0,12078821 0,14241582 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,12078821 0,14234712 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,12078821 0,14227849 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,12078821 0,14220992 ! response to starvation GO:0042594 47 27 0,000 0,12078821 0,14214142 ! response to toxin GO:0009636 49 27 0,000 0,12078821 0,14207298 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,12078821 0,14200461 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,12078821 0,14193631 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,12078821 0,14186807 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,12078821 0,1417999 ! leukocyte proliferation GO:0070661 59 27 0,000 0,12078821 0,14173179 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,12078821 0,14166375 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,12497175 0,14649999 ! neuron fate commitment GO:0048663 52 28 0,000 0,12497175 0,14642972 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,12497175 0,14635953 ! circadian rhythm GO:0007623 56 28 0,000 0,12497175 0,1462894 ! dendrite development GO:0016358 67 28 0,000 0,12497175 0,14621934 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,12497175 0,14614934 ! sperm motility GO:0030317 37 28 0,000 0,12497175 0,14607941 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,12497175 0,14600955 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,12497175 0,14593976 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,12497175 0,14587003 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,12497175 0,14580037 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,12497175 0,14573078 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,12497175 0,14566125 ! glutathione metabolic process GO:0006749 42 28 0,000 0,12497175 0,14559179 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,12497175 0,14552239 ! lipid oxidation GO:0034440 48 28 0,000 0,12497175 0,14545306 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,12497175 0,1453838 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,1291355 0,15015613 ! translational initiation GO:0006413 66 29 0,000 0,1291355 0,15008469 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,1291355 0,15001332 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,1291355 0,14994202 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,1291355 0,14987079 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,1291355 0,14979963 ! primary neural tube formation GO:0014020 61 29 0,000 0,1291355 0,14972853 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,1291355 0,1496575 ! synaptogenesis GO:0007416 46 29 0,000 0,1291355 0,14958654 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,1291355 0,14951565 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,1291355 0,14944482 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,1291355 0,14937406 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,13327955 0,15409463 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,13327955 0,15402173 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,13327955 0,15394891 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,13327955 0,15387616 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,13327955 0,15380347 ! acute-phase response GO:0006953 50 30 0,000 0,13327955 0,15373085 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,13327955 0,1536583 ! myofibril assembly GO:0030239 50 30 0,000 0,13327955 0,15358582 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,13327955 0,15351341 ! cell fate determination GO:0001709 64 30 0,000 0,13327955 0,15344107 ! phospholipid transport GO:0015914 65 30 0,000 0,13327955 0,15336879 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,13327955 0,15329658 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,13327955 0,15322444 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,13327955 0,15315237 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,13327955 0,15308037 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,13327955 0,15300843 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,137404 0,15766932 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,137404 0,1575953 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,137404 0,15752134 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,137404 0,15744746 ! cell junction assembly GO:0034329 85 31 0,000 0,137404 0,15737364 ! regulation of innate immune response GO:0045088 57 31 0,000 0,137404 0,1572999 ! ovulation cycle process GO:0022602 55 31 0,000 0,137404 0,15722622 ! peptide transport GO:0015833 60 31 0,000 0,137404 0,15715261 ! male gonad development GO:0008584 56 31 0,000 0,137404 0,15707907 ! iron ion homeostasis GO:0055072 60 31 0,000 0,137404 0,1570056 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,137404 0,1569322 ! detection of light stimulus GO:0009583 44 31 0,000 0,137404 0,15685887 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,137404 0,1567856 ! natural killer cell activation GO:0030101 50 31 0,000 0,137404 0,15671241 ! ensheathment of neurons GO:0007272 64 31 0,000 0,137404 0,15663928 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,137404 0,15656622 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,137404 0,15649323 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,137404 0,15642031 ! eye morphogenesis GO:0048592 65 31 0,000 0,137404 0,15634745 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,14150894 0,16094336 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,14150894 0,16086847 ! collagen metabolic process GO:0032963 49 32 0,000 0,14150894 0,16079365 ! spindle organization GO:0007051 50 32 0,000 0,14150894 0,1607189 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,14150894 0,16064421 ! metanephros development GO:0001656 81 32 0,000 0,14150894 0,1605696 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,14150894 0,16049505 ! muscle cell development GO:0055001 52 32 0,000 0,14150894 0,16042058 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,14150894 0,16034617 ! ovulation cycle GO:0042698 57 32 0,000 0,14150894 0,16027183 ! peripheral nervous system development GO:0007422 68 32 0,000 0,14150894 0,16019757 ! gene silencing GO:0016458 71 32 0,000 0,14150894 0,16012337 ! regulation of pH GO:0006885 56 33 0,000 0,14559446 0,16467003 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,14559446 0,16459383 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,14559446 0,1645177 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,14559446 0,16444164 ! response to ionizing radiation GO:0010212 74 33 0,000 0,14559446 0,16436565 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,14559446 0,16428973 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,14559446 0,16421388 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,14559446 0,1641381 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,14559446 0,16406239 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,14559446 0,16398676 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,14559446 0,16391119 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,14966065 0,16841132 ! glial cell differentiation GO:0010001 67 34 0,000 0,14966065 0,16833378 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,14966065 0,16825632 ! spliceosome assembly GO:0000245 75 34 0,000 0,14966065 0,16817892 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,14966065 0,1681016 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,14966065 0,16802435 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,14966065 0,16794717 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,15370761 0,17240941 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,15370761 0,17233028 ! negative regulation of secretion GO:0051048 68 35 0,000 0,15370761 0,17225123 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,15370761 0,17217225 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,15370761 0,17209335 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,15370761 0,17201452 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,15370761 0,17193575 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,15370761 0,17185707 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,15370761 0,17177845 ! ceramide metabolic process GO:0006672 72 35 0,000 0,15370761 0,1716999 ! telencephalon development GO:0021537 81 35 0,000 0,15370761 0,17162143 ! vesicle localization GO:0051648 70 35 0,000 0,15370761 0,17154303 ! regulation of muscle development GO:0048634 82 36 0,000 0,15773542 0,17595782 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,15773542 0,17587751 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,15773542 0,17579727 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,15773542 0,17571711 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,15773542 0,17563702 ! positive regulation of cell development GO:0010720 85 36 0,000 0,15773542 0,175557 ! protein targeting to membrane GO:0006612 75 36 0,000 0,15773542 0,17547706 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,15773542 0,17539719 ! aerobic respiration GO:0009060 56 36 0,000 0,15773542 0,17531739 ! cytokine production GO:0001816 68 36 0,000 0,15773542 0,17523766 ! embryonic organ development GO:0048568 67 36 0,000 0,15773542 0,17515801 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,15773542 0,17507843 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,15773542 0,17499892 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,16174417 0,17936496 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,16174417 0,17928357 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,16174417 0,17920227 ! sister chromatid segregation GO:0000819 65 37 0,000 0,16174417 0,17912103 ! odontogenesis GO:0042476 74 37 0,000 0,16174417 0,17903987 ! actomyosin structure organization GO:0031032 68 37 0,000 0,16174417 0,17895879 ! cell junction organization GO:0034330 96 37 0,000 0,16174417 0,17887777 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,16174417 0,17879683 ! female gonad development GO:0008585 71 37 0,000 0,16174417 0,17871597 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,16174417 0,17863517 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,16174417 0,17855445 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,16573395 0,18287626 ! meiosis I GO:0007127 74 38 0,000 0,16573395 0,1827937 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,16573395 0,18271121 ! organic anion transport GO:0015711 82 38 0,000 0,16573395 0,1826288 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,16573395 0,18254646 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,16573395 0,18246419 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,16573395 0,182382 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,16573395 0,18229988 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,16573395 0,18221784 ! regulation of protein stability GO:0031647 77 38 0,000 0,16573395 0,18213587 ! spermatid development GO:0007286 69 38 0,000 0,16573395 0,18205397 ! pigment metabolic process GO:0042440 87 38 0,000 0,16573395 0,18197215 ! neural tube formation GO:0001841 79 38 0,000 0,16573395 0,1818904 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,16970486 0,18616478 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,16970486 0,18608122 ! negative regulation of binding GO:0051100 71 39 0,000 0,16970486 0,18599774 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,16970486 0,18591433 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,16970486 0,185831 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,16970486 0,18574774 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,16970486 0,18566456 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,17365697 0,1899033 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,17365697 0,18981834 ! learning GO:0007612 82 40 0,000 0,17365697 0,18973344 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,17365697 0,18964863 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,17365697 0,18956389 ! mismatch repair GO:0006298 58 40 0,000 0,17365697 0,18947922 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,17365697 0,18939463 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,17365697 0,18931012 ! RNA export from nucleus GO:0006405 61 41 0,000 0,17759039 0,19351174 ! mRNA catabolic process GO:0006402 79 41 0,000 0,17759039 0,19342546 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,17759039 0,19333927 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,17759039 0,19325315 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,17759039 0,1931671 ! gliogenesis GO:0042063 91 41 0,000 0,17759039 0,19308114 ! feeding behavior GO:0007631 69 41 0,000 0,17759039 0,19299525 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,17759039 0,19290943 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,17759039 0,1928237 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,17759039 0,19273803 ! spermatid differentiation GO:0048515 73 41 0,000 0,17759039 0,19265245 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,17759039 0,19256694 ! RNA modification GO:0009451 64 41 0,000 0,17759039 0,19248151 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,18150519 0,19663733 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,18150519 0,19655017 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,18150519 0,19646308 ! regulation of protein secretion GO:0050708 77 42 0,000 0,18150519 0,19637607 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,18150519 0,19628914 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,18150519 0,19620229 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,18540147 0,20032542 ! regulation of tube size GO:0035150 76 43 0,000 0,18540147 0,20023686 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,18540147 0,20014838 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,18540147 0,20005997 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,18540147 0,19997165 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,18540147 0,1998834 ! ion transmembrane transport GO:0034220 79 43 0,000 0,18540147 0,19979523 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,18540147 0,19970713 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,1892793 0,20379433 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,1892793 0,20370456 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,1892793 0,20361486 ! striated muscle contraction GO:0006941 85 44 0,000 0,1892793 0,20352524 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,1892793 0,2034357 ! double-strand break repair GO:0006302 85 44 0,000 0,1892793 0,20334624 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,19313879 0,20740135 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,19313879 0,20731022 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,19313879 0,20721918 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,19313879 0,20712821 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,19313879 0,20703733 ! biopolymer methylation GO:0043414 91 45 0,000 0,19313879 0,20694652 ! B cell differentiation GO:0030183 124 45 0,000 0,19313879 0,20685579 ! female gamete generation GO:0007292 71 45 0,000 0,19313879 0,20676515 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,19313879 0,20667458 ! maintenance of location in cell GO:0051651 101 45 0,000 0,19313879 0,20658409 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,19698001 0,21060051 ! glycolysis GO:0006096 71 46 0,000 0,19698001 0,21050839 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,19698001 0,21041634 ! pigmentation GO:0043473 103 46 0,000 0,19698001 0,21032438 ! neural tube development GO:0021915 91 47 0,000 0,20080306 0,21431274 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,20460801 0,21827832 ! mitochondrial transport GO:0006839 94 48 0,000 0,20460801 0,21818305 ! cellular component disassembly GO:0022411 89 48 0,000 0,20460801 0,21808785 ! endosome transport GO:0016197 127 48 0,000 0,20460801 0,21799274 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,20460801 0,21789772 ! male sex differentiation GO:0046661 93 48 0,000 0,20460801 0,21780277 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,20460801 0,21770791 ! methylation GO:0032259 97 48 0,000 0,20460801 0,21761313 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,20839495 0,22154432 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,20839495 0,22144796 ! regulation of action potential GO:0001508 102 50 0,000 0,21216396 0,22535503 ! regulation of ion transport GO:0043269 86 50 0,000 0,21216396 0,22525709 ! endocrine system development GO:0035270 109 50 0,000 0,21216396 0,22515924 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,21216396 0,22506147 ! activation of caspase activity GO:0006919 95 50 0,000 0,21216396 0,22496379 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,21216396 0,22486619 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,21216396 0,22476867 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,21216396 0,22467125 ! peptide metabolic process GO:0006518 80 51 0,000 0,21591514 0,22854449 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,21591514 0,22844551 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,21591514 0,22834662 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,21964856 0,23219448 ! Notch signaling pathway GO:0007219 111 52 0,000 0,21964856 0,23209405 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,21964856 0,2319937 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,21964856 0,23189345 ! excretion GO:0007588 87 52 0,000 0,21964856 0,23179328 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,21964856 0,23169319 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,21964856 0,2315932 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,21964856 0,23149329 ! amino acid activation GO:0043038 98 52 0,000 0,21964856 0,23139346 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,22336431 0,23520647 ! chromatin remodeling GO:0006338 122 53 0,000 0,22336431 0,23510513 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,22336431 0,23500388 ! cartilage development GO:0051216 99 53 0,000 0,22336431 0,23490272 ! synapse organization GO:0050808 102 53 0,000 0,22336431 0,23480164 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,22706247 0,2385865 ! regulation of translational initiation GO:0006446 87 54 0,000 0,22706247 0,23848393 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,22706247 0,23838145 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,22706247 0,23827905 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,22706247 0,23817674 ! RNA catabolic process GO:0006401 103 55 0,000 0,23074313 0,24193367 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,23074313 0,24182989 ! cell recognition GO:0008037 98 55 0,000 0,23074313 0,24172618 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,23074313 0,24162257 ! glucose catabolic process GO:0006007 88 56 0,000 0,23440636 0,24535336 ! chloride transport GO:0006821 102 57 0,000 0,23805225 0,2490628 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,23805225 0,24895618 GO:0010952|positive regulation of peptidase activity, ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,24168088 0,25264287 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,24168088 0,25253481 ! aging GO:0007568 112 58 0,000 0,24168088 0,25242684 ! nuclear export GO:0051168 110 59 0,000 0,24529233 0,25608938 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,24888668 0,25973095 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,24888668 0,25962005 ! kidney development GO:0001822 133 60 0,000 0,24888668 0,25950925 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,25246402 0,26312696 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,25246402 0,26301475 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,25246402 0,26290264 ! regulation of heart contraction GO:0008016 123 61 0,000 0,25246402 0,26279062 ! camera-type eye development GO:0043010 126 61 0,000 0,25246402 0,2626787 ! proton transport GO:0015992 117 61 0,000 0,25246402 0,26256688 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,25602441 0,26615644 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,25602441 0,26604323 ! tRNA processing GO:0008033 102 62 0,000 0,25602441 0,26593012 ! regulation of mitosis GO:0007088 112 63 0,000 0,25956795 0,26949618 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,25956795 0,26938169 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,25956795 0,26926731 ! hydrogen transport GO:0006818 121 64 0,000 0,26309471 0,27281001 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,26309471 0,27269427 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,26660478 0,27621521 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,26660478 0,27609812 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,26660478 0,27598113 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,26660478 0,27586424 ! gonad development GO:0008406 115 66 0,000 0,27009822 0,27936069 ! chromosome segregation GO:0007059 127 67 0,000 0,27357512 0,28283707 ! secondary metabolic process GO:0019748 125 67 0,000 0,27357512 0,28271743 ! hexose catabolic process GO:0019320 113 68 0,000 0,27703555 0,28617245 ! extracellular matrix organization GO:0030198 146 68 0,000 0,27703555 0,2860515 ! detection of external stimulus GO:0009581 102 68 0,000 0,27703555 0,28593065 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,2804796 0,28936303 ! urogenital system development GO:0001655 149 69 0,000 0,2804796 0,28924088 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,2804796 0,28911884 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,28390733 0,29252873 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,28731884 0,29591902 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,28731884 0,29579432 ! actin filament organization GO:0007015 167 72 0,000 0,29071418 0,29916375 ! B cell activation GO:0042113 179 72 0,000 0,29071418 0,29903779 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,29071418 0,29891193 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,29071418 0,29878618 ! humoral immune response GO:0006959 115 73 0,000 0,29409345 0,30213217 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,29409345 0,30200517 ! acute inflammatory response GO:0002526 118 74 0,000 0,29745671 0,30533056 ! amino acid transport GO:0006865 148 74 0,000 0,29745671 0,30520233 ! transition metal ion transport GO:0000041 143 75 0,000 0,30080404 0,30850725 ! reproductive structure development GO:0048608 131 75 0,000 0,30080404 0,30837779 ! eye development GO:0001654 155 75 0,000 0,30080404 0,30824843 ! axon guidance GO:0007411 162 75 0,000 0,30080404 0,30811919 ! rhythmic process GO:0048511 142 75 0,000 0,30080404 0,30799005 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,30413551 0,31127066 ! learning or memory GO:0007611 161 76 0,000 0,30413551 0,31114031 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,30413551 0,31101007 ! regulation of blood pressure GO:0008217 134 76 0,000 0,30413551 0,31087994 ! amine catabolic process GO:0009310 136 77 0,000 0,30745121 0,31413773 ! neurotransmitter transport GO:0006836 142 77 0,000 0,30745121 0,3140064 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,30745121 0,31387518 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,30745121 0,31374407 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,3107512 0,3169792 ! blood coagulation GO:0007596 151 79 0,000 0,31403556 0,32019569 GO:0050817|coagulation, ! steroid biosynthetic process GO:0006694 146 79 0,000 0,31403556 0,32006211 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,31403556 0,31992864 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,31403556 0,31979528 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,31730436 0,32298939 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,31730436 0,32285487 ! meiosis GO:0007126 143 81 0,000 0,32055767 0,32602931 GO:0051327|M phase of meiotic cell cycle, ! cell-substrate adhesion GO:0031589 189 82 0,000 0,32379558 0,32918543 ! meiotic cell cycle GO:0051321 144 82 0,000 0,32379558 0,3290485 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,32701814 0,33218516 ! exocytosis GO:0006887 153 83 0,000 0,32701814 0,3320471 ! response to drug GO:0042493 149 83 0,000 0,32701814 0,33190915 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,32701814 0,33177131 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,32701814 0,33163359 ! response to nutrient GO:0007584 135 84 0,000 0,33022544 0,33474719 ! digestion GO:0007586 130 84 0,000 0,33022544 0,33460835 ! hemostasis GO:0007599 165 85 0,000 0,33341754 0,33770275 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,33341754 0,3375628 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,33341754 0,33742297 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,33341754 0,33728325 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,33341754 0,33714364 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,33659451 0,34021531 ! regulation of lyase activity GO:0051339 169 86 0,000 0,33659451 0,34007461 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,33975644 0,34312732 ! cellular respiration GO:0045333 143 88 0,000 0,34290338 0,34616238 ! sensory perception of smell GO:0007608 117 88 0,000 0,34290338 0,3460194 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,34290338 0,34587653 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,34603541 0,34889167 ! tube morphogenesis GO:0035239 194 89 0,000 0,34603541 0,34874774 ! cellular defense response GO:0006968 123 89 0,000 0,34603541 0,34860392 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,3491526 0,35159926 ! response to unfolded protein GO:0006986 139 90 0,000 0,3491526 0,35145439 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,3491526 0,35130964 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,35225503 0,35428531 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! vitamin metabolic process GO:0006766 153 93 0,000 0,35841583 0,36033328 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,36147435 0,36325868 ! female pregnancy GO:0007565 166 94 0,000 0,36147435 0,36310931 ! sterol metabolic process GO:0016125 166 94 0,000 0,36147435 0,36296007 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,36451838 0,36586623 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,36451838 0,36571598 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,36451838 0,36556585 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,36451838 0,36541584 ! sex differentiation GO:0007548 171 96 0,000 0,36754799 0,36830178 ! response to protein stimulus GO:0051789 158 96 0,000 0,36754799 0,36815077 ! forebrain development GO:0030900 210 98 0,000 0,37356419 0,37402349 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,37356419 0,37387026 ! mRNA transport GO:0051028 185 100 0,000 0,37952349 0,37967891 ! hormone metabolic process GO:0042445 171 100 0,000 0,37952349 0,37952349