pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1134-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 1,58E-06 3,634E-03 ! ER overload response GO:0006983 7 6 2,000 1,897E-06 2,182E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 3,000 1,958E-06 1,501E-03 ! dendrite development GO:0016358 35 21 3,000 2,41E-06 1,386E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 5,000 2,869E-06 1,32E-03 ! interphase GO:0051325 159 88 5,000 3,283E-06 1,259E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 2,000 3,309E-06 1,087E-03 ! calcium ion transport GO:0006816 167 99 5,000 6,519E-06 1,874E-03 ! divalent metal ion transport GO:0070838 171 100 5,000 6,91E-06 1,766E-03 ! protein oligomerization GO:0051259 100 65 4,000 1,252E-05 2,88E-03 ! negative regulation of leukocyte proliferation GO:0070664 25 15 2,000 4,189E-05 8,758E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! G1 phase GO:0051318 27 16 2,000 5,138E-05 9,848E-03 ! response to UV GO:0009411 75 46 3,000 6,019E-05 0,01064829 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 6,218E-05 0,01021533 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 6,218E-05 9,534E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 3,000 6,555E-05 9,423E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of DNA replication GO:0006275 75 48 3,000 7,126E-05 9,641E-03 ! positive regulation of translation GO:0045727 28 18 2,000 7,437E-05 9,502E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 8,802E-05 0,0106546 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 2,000 8,802E-05 0,01012187 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 9,056E-05 9,919E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 1,2E-04 0,01254564 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 1,2E-04 0,01200017 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 1,2E-04 0,01150017 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 1,385E-04 0,0127407 ! protein tetramerization GO:0051262 39 22 2,000 1,385E-04 0,01225067 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 1,402E-04 0,01193995 ! negative regulation of kinase activity GO:0033673 100 58 3,000 1,5E-04 0,01232303 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 1,587E-04 0,01258873 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 1,808E-04 0,01386118 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 2,000 1,808E-04 0,01341404 ! negative regulation of transferase activity GO:0051348 105 61 3,000 1,826E-04 0,01312379 ! negative regulation of cell growth GO:0030308 106 62 3,000 1,945E-04 0,0135561 ! negative regulation of lymphocyte activation GO:0051250 37 25 2,000 2,048E-04 0,0138519 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 2,101E-04 0,01380852 ! positive regulation of glycolysis GO:0045821 11 5 1,000 2,101E-04 0,01342495 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 2,101E-04 0,01306212 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 2,101E-04 0,01271838 ! regulation of respiratory burst GO:0060263 8 5 1,000 2,101E-04 0,01239227 ! glial cell migration GO:0008347 10 5 1,000 2,101E-04 0,01208246 ! regulation of sensory perception GO:0051931 6 5 1,000 2,101E-04 0,01178776 GO:0051930|regulation of sensory perception of pain, ! positive regulation of microtubule polymerization GO:0031116 9 5 1,000 2,101E-04 0,0115071 ! cell cycle checkpoint GO:0000075 108 64 3,000 2,2E-04 0,01176656 ! negative regulation of cell size GO:0045792 108 64 3,000 2,2E-04 0,01149914 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 2,307E-04 0,01179155 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 2,000 2,307E-04 0,01153521 ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 2,587E-04 0,01265868 ! regulation of helicase activity GO:0051095 11 6 1,000 3,142E-04 0,01505761 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 3,142E-04 0,01475032 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 3,142E-04 0,01445531 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 3,142E-04 0,01417187 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 1,000 3,142E-04 0,01389934 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! male sex determination GO:0030238 9 6 1,000 3,142E-04 0,01363708 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 3,142E-04 0,01338455 ! gas homeostasis GO:0033483 11 6 1,000 3,142E-04 0,01314119 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 3,142E-04 0,01290653 ! axonal fasciculation GO:0007413 9 6 1,000 3,142E-04 0,0126801 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 1,000 3,142E-04 0,01246147 ! regulation of microtubule polymerization GO:0031113 11 6 1,000 3,142E-04 0,01225026 ! regulation of peptidase activity GO:0052547 106 72 3,000 3,463E-04 0,01327631 ! regulation of microtubule-based process GO:0032886 58 30 2,000 3,555E-04 0,01340319 ! negative regulation of cell activation GO:0050866 44 30 2,000 3,555E-04 0,01318701 ! DNA damage checkpoint GO:0000077 53 31 2,000 3,923E-04 0,01432031 ! negative regulation of growth GO:0045926 123 75 3,000 4,049E-04 0,01455098 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 4,386E-04 0,01552042 ! carbohydrate phosphorylation GO:0046835 8 7 1,000 4,386E-04 0,01528526 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 1,000 4,386E-04 0,01505712 ! microtubule bundle formation GO:0001578 8 7 1,000 4,386E-04 0,01483569 ! vesicle fusion GO:0006906 15 7 1,000 4,386E-04 0,01462068 ! protein heterooligomerization GO:0051291 10 7 1,000 4,386E-04 0,01441181 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 4,386E-04 0,01420883 ! B cell lineage commitment GO:0002326 17 7 1,000 4,386E-04 0,01401149 ! T cell lineage commitment GO:0002360 12 7 1,000 4,386E-04 0,01381955 ! response to tumor cell GO:0002347 12 7 1,000 4,386E-04 0,0136328 ! mitotic cell cycle checkpoint GO:0007093 63 34 2,000 5,17E-04 0,01585436 ! DNA integrity checkpoint GO:0031570 57 34 2,000 5,17E-04 0,01564575 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 5,17E-04 0,01544256 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 5,636E-04 0,01661826 ! glycogen metabolic process GO:0005977 48 35 2,000 5,636E-04 0,01640791 ! protein homooligomerization GO:0051260 52 35 2,000 5,636E-04 0,01620281 ! axon extension GO:0048675 11 8 1,000 5,831E-04 0,01655626 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 5,831E-04 0,01635435 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 1,000 5,831E-04 0,01615731 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 5,831E-04 0,01596496 ! induction of an organ GO:0001759 11 8 1,000 5,831E-04 0,01577714 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 5,831E-04 0,01559368 ! regulation of embryonic development GO:0045995 16 8 1,000 5,831E-04 0,01541444 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 5,831E-04 0,01523928 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 5,831E-04 0,01506805 ! glucan metabolic process GO:0044042 49 36 2,000 6,128E-04 0,01565953 GO:0006073|cellular glucan metabolic process, ! regulation of DNA metabolic process GO:0051052 135 85 3,000 6,513E-04 0,01646119 ! cell cycle arrest GO:0007050 150 86 3,000 6,807E-04 0,01701685 ! regulation of developmental growth GO:0048638 13 9 1,000 7,474E-04 0,01848421 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 7,474E-04 0,01828757 ! regulation of epithelial cell differentiation GO:0030856 13 9 1,000 7,474E-04 0,01809507 ! regulation of glycolysis GO:0006110 15 9 1,000 7,474E-04 0,01790658 ! positive regulation of protein polymerization GO:0032273 15 9 1,000 7,474E-04 0,01772197 ! localization within membrane GO:0051668 15 9 1,000 7,474E-04 0,01754114 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 8,367E-04 0,01943827 ! positive regulation of protein transport GO:0051222 55 40 2,000 8,367E-04 0,01924389 ! cell fate commitment GO:0045165 141 92 3,000 8,77E-04 0,01997169 ! energy reserve metabolic process GO:0006112 59 41 2,000 8,997E-04 0,02028835 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 9,132E-04 0,02039262 ! regulation of B cell proliferation GO:0030888 15 10 1,000 9,314E-04 0,02059933 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 9,314E-04 0,02040314 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 9,314E-04 0,02021066 ! response to X-ray GO:0010165 16 10 1,000 9,314E-04 0,02002178 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 9,314E-04 0,01983639 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 9,314E-04 0,0196544 GO:0043470|regulation of carbohydrate catabolic process, ! developmental induction GO:0031128 13 10 1,000 9,314E-04 0,01947573 GO:0045168|cell-cell signaling involved in cell fate specification, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 9,314E-04 0,01930027 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 9,657E-04 0,01983205 ! regulation of cell shape GO:0008360 78 42 2,000 9,657E-04 0,01965655 ! response to light stimulus GO:0009416 153 96 3,000 1,028E-03 0,02074437 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 1,035E-03 0,0206943 ! response to insulin stimulus GO:0032868 63 43 2,000 1,035E-03 0,0205159 ! virus-host interaction GO:0019048 17 11 1,000 1,135E-03 0,02231227 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 1,135E-03 0,02212318 ! regulation of intracellular pH GO:0051453 17 11 1,000 1,135E-03 0,02193727 ! stem cell development GO:0048864 29 11 1,000 1,135E-03 0,02175446 GO:0019827|stem cell maintenance, ! nucleosome positioning GO:0016584 13 11 1,000 1,135E-03 0,02157467 ! positive regulation of cell cycle GO:0045787 77 45 2,000 1,182E-03 0,02228078 ! cell recognition GO:0008037 58 45 2,000 1,182E-03 0,02209964 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 1,182E-03 0,02192141 ! regulation of translation GO:0006417 151 100 3,000 1,197E-03 0,02202167 ! negative regulation of immune system process GO:0002683 73 47 2,000 1,342E-03 0,02448865 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 1,358E-03 0,02459238 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 1,358E-03 0,02440025 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 1,358E-03 0,0242111 ! gland morphogenesis GO:0022612 23 12 1,000 1,358E-03 0,02402487 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,358E-03 0,02384147 ! response to gamma radiation GO:0010332 20 12 1,000 1,358E-03 0,02366085 ! cellular polysaccharide metabolic process GO:0044264 63 48 2,000 1,426E-03 0,02466427 ! regulation of intracellular transport GO:0032386 78 49 2,000 1,514E-03 0,02599019 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,6E-03 0,02725933 ! positive regulation of protein complex assembly GO:0031334 19 13 1,000 1,6E-03 0,02705889 ! lipid localization GO:0010876 24 13 1,000 1,6E-03 0,02686138 GO:0019915|lipid storage, ! organelle fusion GO:0048284 28 13 1,000 1,6E-03 0,02666673 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 1,6E-03 0,02647489 ! regulation of cellular pH GO:0030641 20 13 1,000 1,6E-03 0,02628578 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 1,6E-03 0,02609936 ! positive regulation of cell migration GO:0030335 92 51 2,000 1,7E-03 0,02753847 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 1,861E-03 0,02993326 ! inositol metabolic process GO:0006020 20 14 1,000 1,861E-03 0,02972539 ! startle response GO:0001964 21 14 1,000 1,861E-03 0,02952039 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 1,000 1,861E-03 0,02931819 ! cellular response to starvation GO:0009267 21 14 1,000 1,861E-03 0,02911875 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 1,861E-03 0,028922 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 1,861E-03 0,02872789 ! G1/S transition checkpoint GO:0031575 33 14 1,000 1,861E-03 0,02853637 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 1,861E-03 0,02834739 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 2,141E-03 0,03239584 ! regulation of vasodilation GO:0042312 24 15 1,000 2,141E-03 0,0321841 ! neuron recognition GO:0008038 22 15 1,000 2,141E-03 0,03197511 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 2,141E-03 0,03176882 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 2,141E-03 0,03156517 ! positive regulation of cell motion GO:0051272 99 56 2,000 2,226E-03 0,03260798 ! DNA damage response, signal transduction GO:0042770 96 56 2,000 2,226E-03 0,0324016 ! regulation of lipid metabolic process GO:0019216 84 56 2,000 2,226E-03 0,03219781 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 2,342E-03 0,03366223 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 2,439E-03 0,0348493 ! protein amino acid acetylation GO:0006473 28 16 1,000 2,439E-03 0,03463418 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 2,439E-03 0,0344217 ! sperm-egg recognition GO:0035036 16 16 1,000 2,439E-03 0,03421182 GO:0007339|binding of sperm to zona pellucida, ! lung development GO:0030324 94 59 2,000 2,585E-03 0,03602678 ! inactivation of MAPK activity GO:0000188 27 17 1,000 2,756E-03 0,03819137 ! stem cell differentiation GO:0048863 36 17 1,000 2,756E-03 0,03796268 ! sensory perception of pain GO:0019233 23 17 1,000 2,756E-03 0,03773671 ! peptidyl-serine modification GO:0018209 27 17 1,000 2,756E-03 0,03751342 ! respiratory tube development GO:0030323 99 62 2,000 2,977E-03 0,04027694 ! positive regulation of DNA replication GO:0045740 29 18 1,000 3,092E-03 0,04158397 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 3,092E-03 0,0413422 ! positive regulation of cytoskeleton organization GO:0051495 33 18 1,000 3,092E-03 0,04110323 ! somitogenesis GO:0001756 24 18 1,000 3,092E-03 0,040867 ! cellular response to nutrient levels GO:0031669 27 18 1,000 3,092E-03 0,04063347 ! cell-cell recognition GO:0009988 20 18 1,000 3,092E-03 0,0404026 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 3,092E-03 0,04017434 ! respiratory system development GO:0060541 100 64 2,000 3,258E-03 0,04209639 ! regulation of caspase activity GO:0043281 97 65 2,000 3,404E-03 0,04374153 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 3,445E-03 0,04402007 ! response to starvation GO:0042594 30 19 1,000 3,445E-03 0,04377687 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 3,445E-03 0,04353634 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 3,445E-03 0,04329843 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 3,445E-03 0,04306312 GO:0010675|regulation of cellular carbohydrate metabolic process, ! sex determination GO:0007530 29 19 1,000 3,445E-03 0,04283034 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 3,445E-03 0,04260007 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 3,709E-03 0,04561686 ! protein amino acid O-linked glycosylation GO:0006493 29 20 1,000 3,816E-03 0,04668958 ! microtubule-based transport GO:0010970 37 20 1,000 3,816E-03 0,04644254 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 3,816E-03 0,04619811 ! positive regulation of B cell activation GO:0050871 31 20 1,000 3,816E-03 0,04595623 ! protein amino acid acylation GO:0043543 37 21 1,000 4,205E-03 0,05037786 ! vesicle docking GO:0048278 27 21 1,000 4,205E-03 0,05011684 ! cell aging GO:0007569 32 21 1,000 4,205E-03 0,0498585 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 4,205E-03 0,04960282 ! regulation of vasoconstriction GO:0019229 31 21 1,000 4,205E-03 0,04934974 ! response to hypoxia GO:0001666 132 72 2,000 4,542E-03 0,05302331 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 4,612E-03 0,05357552 ! vasculogenesis GO:0001570 33 22 1,000 4,612E-03 0,0533063 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 4,612E-03 0,05303977 ! regulation of smooth muscle contraction GO:0006940 36 22 1,000 4,612E-03 0,05277589 ! membrane depolarization GO:0051899 35 22 1,000 4,612E-03 0,05251462 ! regulation of blood coagulation GO:0030193 34 22 1,000 4,612E-03 0,05225593 ! response to oxygen levels GO:0070482 137 74 2,000 4,904E-03 0,05528747 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 4,904E-03 0,05501778 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 5,036E-03 0,05623042 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 5,036E-03 0,05595877 ! negative regulation of DNA replication GO:0008156 35 23 1,000 5,036E-03 0,05568974 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 5,036E-03 0,05542328 ! interaction with host GO:0051701 37 23 1,000 5,036E-03 0,05515936 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 5,036E-03 0,05489794 ! cell fate determination GO:0001709 45 23 1,000 5,036E-03 0,05463899 ! regulation of cell morphogenesis GO:0022604 140 76 2,000 5,283E-03 0,05704579 ! regulation of protein transport GO:0051223 114 76 2,000 5,283E-03 0,05677922 GO:0070201|regulation of establishment of protein localization, ! regulation of cellular catabolic process GO:0031329 36 24 1,000 5,478E-03 0,05859863 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 5,478E-03 0,05832734 ! sperm motility GO:0030317 27 24 1,000 5,478E-03 0,05805855 ! mitochondrial membrane organization GO:0007006 39 24 1,000 5,478E-03 0,05779222 ! negative regulation of cell development GO:0010721 56 24 1,000 5,478E-03 0,05752833 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 5,478E-03 0,05726684 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 5,478E-03 0,05700771 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 5,936E-03 0,06150131 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 5,936E-03 0,06122552 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 5,936E-03 0,06095219 ! regulation of pH GO:0006885 36 26 1,000 6,412E-03 0,06554154 ! post-embryonic development GO:0009791 42 26 1,000 6,412E-03 0,06525153 ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 6,412E-03 0,06496408 ! regulation of coagulation GO:0050818 39 26 1,000 6,412E-03 0,06467915 ! membrane docking GO:0022406 39 27 1,000 6,904E-03 0,0693406 ! respiratory gaseous exchange GO:0007585 47 27 1,000 6,904E-03 0,06903912 ! response to ionizing radiation GO:0010212 47 27 1,000 6,904E-03 0,06874025 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 7,205E-03 0,07142818 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 7,205E-03 0,07112162 ! regulation of protein localization GO:0032880 132 85 2,000 7,205E-03 0,07081768 ! cholesterol homeostasis GO:0042632 46 28 1,000 7,413E-03 0,07255052 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 34 28 1,000 7,413E-03 0,0722431 ! erythrocyte differentiation GO:0030218 38 28 1,000 7,413E-03 0,07193828 ! mesoderm formation GO:0001707 46 28 1,000 7,413E-03 0,07163602 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 7,413E-03 0,07133628 ! neural tube formation GO:0001841 41 28 1,000 7,413E-03 0,07103905 ! positive regulation of catabolic process GO:0009896 40 28 1,000 7,413E-03 0,07074428 ! regulation of B cell activation GO:0050864 42 28 1,000 7,413E-03 0,07045195 ! skeletal muscle tissue development GO:0007519 123 87 2,000 7,681E-03 0,07270172 GO:0060538|skeletal muscle organ development, ! regulation of protein import into nucleus GO:0042306 53 29 1,000 7,938E-03 0,07482623 ! formation of primary germ layer GO:0001704 48 29 1,000 7,938E-03 0,07452082 ! cholesterol transport GO:0030301 46 30 1,000 8,48E-03 0,07928177 GO:0015918|sterol transport, ! adult locomotory behavior GO:0008344 47 30 1,000 8,48E-03 0,07896079 ! embryonic epithelial tube formation GO:0001838 44 30 1,000 8,48E-03 0,0786424 ! mammary gland development GO:0030879 57 31 1,000 9,037E-03 0,08347852 ! segmentation GO:0035282 41 31 1,000 9,037E-03 0,08314461 ! mesoderm morphogenesis GO:0048332 49 31 1,000 9,037E-03 0,08281335 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 9,037E-03 0,08248473 ! cell fate specification GO:0001708 37 31 1,000 9,037E-03 0,0821587 ! regulation of cytoskeleton organization GO:0051493 154 93 2,000 9,219E-03 0,08348315 ! polysaccharide metabolic process GO:0005976 129 93 2,000 9,219E-03 0,08315576 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 9,611E-03 0,08635058 ! neutral lipid metabolic process GO:0006638 41 32 1,000 9,611E-03 0,08601459 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 9,611E-03 0,0856812 ! calcium-mediated signaling GO:0019722 50 32 1,000 9,611E-03 0,08535038 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 9,611E-03 0,08502211 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,01020076 0,08989175 ! carbohydrate homeostasis GO:0033500 39 33 1,000 0,01020076 0,08954865 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 55 33 1,000 0,01020076 0,08920816 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,01020076 0,08887025 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,01020076 0,08853489 ! glycerol ether metabolic process GO:0006662 44 34 1,000 0,010806 0,0934353 ! erythrocyte homeostasis GO:0034101 45 34 1,000 0,010806 0,09308535 ! neuron migration GO:0001764 46 34 1,000 0,010806 0,09273802 ! polyol metabolic process GO:0019751 44 34 1,000 0,010806 0,09239327 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,01142675 0,09733896 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01206286 0,10237855 GO:0090047|positive regulation of transcription regulator activity, ! organic ether metabolic process GO:0018904 46 36 1,000 0,01206286 0,10200216 ! tissue remodeling GO:0048771 62 36 1,000 0,01206286 0,10162853 ! neural tube development GO:0021915 50 36 1,000 0,01206286 0,10125762 ! gliogenesis GO:0042063 71 38 1,000 0,01338058 0,11191033 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,01338058 0,11150486 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,01406188 0,11675932 ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 0,01406188 0,11633932 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,01406188 0,11592234 ! cell growth GO:0016049 61 39 1,000 0,01406188 0,11550833 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 1,000 0,01475795 0,12079458 ! T cell differentiation GO:0030217 65 40 1,000 0,01475795 0,12036623 ! double-strand break repair GO:0006302 67 40 1,000 0,01475795 0,1199409 ! B cell differentiation GO:0030183 62 40 1,000 0,01475795 0,11951858 ! epidermal cell differentiation GO:0009913 53 40 1,000 0,01475795 0,11909921 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,01475795 0,11868278 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,01546862 0,12396458 ! mitochondrial transport GO:0006839 60 42 1,000 0,01619377 0,12932523 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,01619377 0,12887773 ! positive regulation of binding GO:0051099 59 43 1,000 0,01693323 0,13429806 ! neuromuscular process GO:0050905 79 43 1,000 0,01693323 0,13383655 ! activation of caspase activity GO:0006919 65 43 1,000 0,01693323 0,13337821 ! vesicle organization GO:0016050 79 43 1,000 0,01693323 0,13292299 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,01693323 0,13247087 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,01768688 0,13789768 ! regulation of translational initiation GO:0006446 64 45 1,000 0,01845455 0,14339686 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,01923612 0,14896657 ! histone modification GO:0016570 68 46 1,000 0,01923612 0,14846668 ! covalent chromatin modification GO:0016569 75 47 1,000 0,02003143 0,15408794 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,02003143 0,15357431 ! regulation of protein polymerization GO:0032271 71 47 1,000 0,02003143 0,1530641 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,02084035 0,15871792 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 1,000 0,02084035 0,1581941 ! gastrulation GO:0007369 73 48 1,000 0,02084035 0,15767372 ! heart morphogenesis GO:0003007 65 48 1,000 0,02084035 0,15715676 ! membrane fusion GO:0006944 80 50 1,000 0,02249846 0,16910607 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,02249846 0,16855524 ! positive regulation of growth GO:0045927 67 50 1,000 0,02249846 0,16800798 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,0229556 0,17086694 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,0229556 0,17031576 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,0229556 0,16976812 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,0229556 0,16922399 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,0229556 0,16868334 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0229556 0,16814613 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,0229556 0,16761233 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,0229556 0,16708191 ! sleep GO:0030431 11 5 0,000 0,0229556 0,16655484 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0229556 0,16603108 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,0229556 0,16551061 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,0229556 0,16499339 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,0229556 0,16447939 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,0229556 0,16396859 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,0229556 0,16346094 ! tongue development GO:0043586 6 5 0,000 0,0229556 0,16295643 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,0229556 0,16245503 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0229556 0,1619567 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,0229556 0,16146142 ! cobalt ion transport GO:0006824 9 5 0,000 0,0229556 0,16096916 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,0229556 0,16047989 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,0229556 0,15999359 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,0229556 0,15951023 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,0229556 0,15902977 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,0229556 0,15855221 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,0229556 0,1580775 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,0229556 0,15760563 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,0229556 0,15713656 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,0229556 0,15667028 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0229556 0,15620676 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0229556 0,15574597 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0229556 0,1552879 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,0229556 0,15483251 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0229556 0,15437978 ! malate metabolic process GO:0006108 7 5 0,000 0,0229556 0,15392969 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,0229556 0,15348222 ! behavioral response to pain GO:0048266 7 5 0,000 0,0229556 0,15303735 ! clathrin coat assembly GO:0048268 11 5 0,000 0,0229556 0,15259504 ! phototransduction, visible light GO:0007603 6 5 0,000 0,0229556 0,15215529 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0229556 0,15171806 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,0229556 0,15128334 ! mating behavior GO:0007617 6 5 0,000 0,0229556 0,1508511 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0229556 0,15042132 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,0229556 0,14999399 ! rhythmic behavior GO:0007622 12 5 0,000 0,0229556 0,14956908 ! copulation GO:0007620 7 5 0,000 0,0229556 0,14914657 ! glial cell fate commitment GO:0021781 12 5 0,000 0,0229556 0,14872644 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,0229556 0,14830866 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,0229556 0,14789323 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,0229556 0,14748012 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,0229556 0,14706932 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,0229556 0,14666079 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,0229556 0,14625453 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,0229556 0,14585051 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0229556 0,14544872 ! response to protozoan GO:0001562 9 5 0,000 0,0229556 0,14504913 ! lymph vessel development GO:0001945 7 5 0,000 0,0229556 0,14465174 ! endochondral ossification GO:0001958 12 5 0,000 0,0229556 0,14425652 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,0229556 0,14386345 ! parathyroid gland development GO:0060017 8 5 0,000 0,0229556 0,14347251 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,0229556 0,1430837 ! anagen GO:0042640 6 5 0,000 0,0229556 0,14269699 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,0229556 0,14231236 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,0229556 0,1419298 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,0229556 0,14154929 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,0229556 0,14117081 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,0229556 0,14079436 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,0229556 0,14041991 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,0229556 0,14004744 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,0229556 0,13967694 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,0229556 0,1393084 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,0229556 0,1389418 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,0229556 0,13857712 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,0229556 0,13821436 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,0229556 0,13785348 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,0229556 0,13749449 ! ovulation GO:0030728 6 5 0,000 0,0229556 0,13713736 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,0229556 0,13678208 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,0229556 0,13642864 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,0229556 0,13607702 ! response to pH GO:0009268 9 5 0,000 0,0229556 0,13572721 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,0229556 0,13537919 ! proline biosynthetic process GO:0006561 6 5 0,000 0,0229556 0,13503295 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0229556 0,13468848 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,0229556 0,13434576 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0229556 0,13400478 ! polyol catabolic process GO:0046174 7 5 0,000 0,0229556 0,13366553 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0229556 0,13332799 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0229556 0,13299215 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0229556 0,132658 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,0229556 0,13232553 ! nerve growth factor processing GO:0032455 7 5 0,000 0,0229556 0,13199471 ! urea metabolic process GO:0019627 6 5 0,000 0,0229556 0,13166555 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,0229556 0,13133802 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0229556 0,13101212 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,0229556 0,13068783 ! neutrophil activation GO:0042119 5 5 0,000 0,0229556 0,13036515 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,0229556 0,13004405 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,0229556 0,12972453 ! response to food GO:0032094 5 5 0,000 0,0229556 0,12940658 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,0229556 0,12909018 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0229556 0,12877533 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,0229556 0,12846201 ! forebrain neuron development GO:0021884 7 5 0,000 0,0229556 0,12815021 ! melanosome organization GO:0032438 7 5 0,000 0,0229556 0,12783991 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,0229556 0,12753112 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0229556 0,12722382 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,0229556 0,12691799 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0229556 0,12661363 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,0229556 0,12631073 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,0229556 0,12600927 ! nucleoside transport GO:0015858 6 5 0,000 0,0229556 0,12570925 ! nucleoside salvage GO:0043174 7 5 0,000 0,0229556 0,12541065 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,0229556 0,12511347 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0229556 0,12481769 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,0229556 0,12452331 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,0229556 0,12423032 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,0229556 0,1239387 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0229556 0,12364844 ! depyrimidination GO:0045008 8 5 0,000 0,0229556 0,12335954 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,0229556 0,12307199 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,0229556 0,12278578 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,0229556 0,12250089 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0229556 0,12221733 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,0229556 0,12193507 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,0229556 0,12165411 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,0229556 0,12137445 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,0229556 0,12109607 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,0229556 0,12081896 ! monocyte differentiation GO:0030224 8 5 0,000 0,0229556 0,12054312 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,0229556 0,12026853 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0229556 0,11999519 ! centrosome duplication GO:0051298 5 5 0,000 0,0229556 0,11972309 ! response to UV-C GO:0010225 6 5 0,000 0,0229556 0,11945223 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,0229556 0,11918258 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,0229556 0,11891415 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,0229556 0,11864693 ! regulation of dendrite development GO:0050773 12 5 0,000 0,0229556 0,11838091 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,0229556 0,11811607 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0229556 0,11785242 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,0229556 0,11758994 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,0229556 0,11732863 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,0229556 0,11706848 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,0229556 0,11680948 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,0229556 0,11655162 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,0229556 0,1162949 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,0229556 0,11603931 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0229556 0,11578483 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,0229556 0,11553148 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0229556 0,11527922 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0229556 0,11502807 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,0229556 0,11477801 ! neural tube patterning GO:0021532 6 5 0,000 0,0229556 0,11452903 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,0229556 0,11428114 ! histone demethylation GO:0016577 9 5 0,000 0,0229556 0,11403431 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0229556 0,11378854 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0229556 0,11354384 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,0229556 0,11330018 ! enteric nervous system development GO:0048484 8 5 0,000 0,0229556 0,11305757 ! establishment of planar polarity GO:0001736 6 5 0,000 0,0229556 0,11281599 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,0229556 0,11257545 ! muscle cell proliferation GO:0033002 8 5 0,000 0,0229556 0,11233592 ! transcription termination GO:0006353 8 5 0,000 0,0229556 0,11209742 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,0229556 0,11185992 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,0229556 0,11162343 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,0229556 0,11138794 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,0229556 0,11115344 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0229556 0,11091993 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0229556 0,11068739 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,0229556 0,11045583 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,0229556 0,11022523 ! apical protein localization GO:0045176 6 5 0,000 0,0229556 0,10999559 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,0229556 0,10976691 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,0229556 0,10953918 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0229556 0,10931239 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0229556 0,10908654 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,0229556 0,10886162 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,0229556 0,10863762 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,0229556 0,10841455 ! determination of adult lifespan GO:0008340 8 5 0,000 0,0229556 0,10819239 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,0229556 0,10797113 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0229556 0,10775078 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0229556 0,10753133 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,0229556 0,10731277 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,0229556 0,1070951 ! neural plate development GO:0001840 6 5 0,000 0,0229556 0,10687831 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,0229556 0,10666239 ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,0229556 0,10644735 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,0229556 0,10623317 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,0229556 0,10601985 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,0229556 0,10580738 ! sensory cilium assembly GO:0035058 6 5 0,000 0,0229556 0,10559577 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,0229556 0,105385 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0229556 0,10517507 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,0229556 0,10496597 ! spindle assembly GO:0051225 5 5 0,000 0,0229556 0,10475771 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,0229556 0,10455027 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,0229556 0,10434365 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,0229556 0,10413784 ! organ regeneration GO:0031100 7 5 0,000 0,0229556 0,10393284 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,0229556 0,10372865 ! carnitine metabolic process GO:0009437 5 5 0,000 0,0229556 0,10352526 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 6 5 0,000 0,0229556 0,10332267 GO:0055081|anion homeostasis, ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,02334737 0,10488076 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,02334737 0,10467631 ! adult behavior GO:0030534 80 51 1,000 0,02334737 0,10447266 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,02420933 0,10811934 ! aging GO:0007568 79 52 1,000 0,02420933 0,10790981 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,02420933 0,10770108 ! single fertilization GO:0007338 59 53 1,000 0,02508421 0,11137777 ! regulation of protein complex assembly GO:0043254 81 54 1,000 0,02597187 0,11509694 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,02597187 0,1148756 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,02597187 0,11465511 ! mesoderm development GO:0007498 76 55 1,000 0,02687219 0,11840235 ! tRNA transcription GO:0009304 11 6 0,000 0,02748387 0,12086598 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02748387 0,12063532 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02748387 0,12040554 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02748387 0,12017663 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02748387 0,11994859 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02748387 0,11972142 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02748387 0,1194951 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02748387 0,11926964 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02748387 0,11904503 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02748387 0,11882126 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02748387 0,11859833 ! prostate gland development GO:0030850 9 6 0,000 0,02748387 0,11837623 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02748387 0,11815497 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02748387 0,11793453 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02748387 0,11771491 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02748387 0,11749611 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02748387 0,11727812 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02748387 0,11706094 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02748387 0,11684456 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02748387 0,11662898 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02748387 0,1164142 ! neuron adhesion GO:0007158 9 6 0,000 0,02748387 0,1162002 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02748387 0,11598699 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02748387 0,11577456 ! signal peptide processing GO:0006465 8 6 0,000 0,02748387 0,1155629 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02748387 0,11535202 ! mRNA stabilization GO:0048255 15 6 0,000 0,02748387 0,11514191 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02748387 0,11493256 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02748387 0,11472397 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02748387 0,11451614 ! opsonization GO:0008228 8 6 0,000 0,02748387 0,11430906 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02748387 0,11410272 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02748387 0,11389713 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02748387 0,11369228 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02748387 0,11348817 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02748387 0,11328478 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02748387 0,11308213 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02748387 0,11288019 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02748387 0,11267898 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02748387 0,11247848 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02748387 0,1122787 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02748387 0,11207962 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02748387 0,11188125 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02748387 0,11168358 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02748387 0,11148661 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02748387 0,11129033 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02748387 0,11109474 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02748387 0,11089984 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02748387 0,11070562 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02748387 0,11051208 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02748387 0,11031921 ! thymic T cell selection GO:0045061 12 6 0,000 0,02748387 0,11012702 ! protein lipoylation GO:0009249 10 6 0,000 0,02748387 0,10993549 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02748387 0,10974463 ! pigment granule organization GO:0048753 11 6 0,000 0,02748387 0,10955443 ! drug transport GO:0015893 6 6 0,000 0,02748387 0,10936489 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02748387 0,10917601 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02748387 0,10898777 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02748387 0,10880019 ! histidine metabolic process GO:0006547 6 6 0,000 0,02748387 0,10861324 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02748387 0,10842694 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02748387 0,10824128 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 0,02748387 0,10805625 ! adenohypophysis development GO:0021984 10 6 0,000 0,02748387 0,10787186 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02748387 0,10768809 ! hyperosmotic response GO:0006972 8 6 0,000 0,02748387 0,10750495 ! microtubule nucleation GO:0007020 10 6 0,000 0,02748387 0,10732243 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02748387 0,10714052 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02748387 0,10695924 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02748387 0,10677856 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02748387 0,1065985 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02748387 0,10641904 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02748387 0,10624018 ! response to dietary excess GO:0002021 7 6 0,000 0,02748387 0,10606193 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02748387 0,10588427 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02748387 0,1057072 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02748387 0,10553073 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02748387 0,10535485 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02748387 0,10517955 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02748387 0,10500483 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02748387 0,10483069 ! neuron apoptosis GO:0051402 8 6 0,000 0,02748387 0,10465713 ! organic alcohol transport GO:0015850 9 6 0,000 0,02748387 0,10448415 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02748387 0,10431173 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02748387 0,10413988 ! carnitine transport GO:0015879 8 6 0,000 0,02748387 0,1039686 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02748387 0,10379788 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02748387 0,10362772 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02748387 0,10345812 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02748387 0,10328907 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02748387 0,10312057 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02748387 0,10295262 ! parturition GO:0007567 12 6 0,000 0,02748387 0,10278522 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02748387 0,10261836 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02748387 0,10245204 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02748387 0,10228626 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02748387 0,10212102 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02748387 0,1019563 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02748387 0,10179212 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02748387 0,10162847 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02748387 0,10146534 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02748387 0,10130274 ! macrophage differentiation GO:0030225 10 6 0,000 0,02748387 0,10114065 ! astrocyte development GO:0014002 14 6 0,000 0,02748387 0,10097909 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02748387 0,10081804 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02748387 0,1006575 ! interaction with symbiont GO:0051702 8 6 0,000 0,02748387 0,10049747 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02748387 0,10033795 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02748387 0,10017894 ! eating behavior GO:0042755 6 6 0,000 0,02748387 0,10002042 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02748387 0,09986241 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02748387 0,0997049 ! response to copper ion GO:0046688 9 6 0,000 0,02748387 0,09954789 ! DNA topological change GO:0006265 8 6 0,000 0,02748387 0,09939137 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02748387 0,09923534 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02748387 0,09907979 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02748387 0,09892474 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02748387 0,09877017 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02748387 0,09861608 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02748387 0,09846247 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02748387 0,09830934 ! hair follicle maturation GO:0048820 7 6 0,000 0,02748387 0,09815669 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02748387 0,09800451 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02748387 0,0978528 ! Schwann cell development GO:0014044 14 6 0,000 0,02748387 0,09770156 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02748387 0,09755078 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02748387 0,09740048 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02748387 0,09725063 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02748387 0,09710124 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02748387 0,09695231 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02748387 0,09680384 ! histone ubiquitination GO:0016574 7 6 0,000 0,02748387 0,09665582 ! regulation of meiosis GO:0040020 10 6 0,000 0,02748387 0,09650826 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02748387 0,09636114 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02748387 0,09621447 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02748387 0,09606825 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02748387 0,09592247 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02748387 0,09577713 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02748387 0,09563224 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02748387 0,09548778 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02748387 0,09534375 ! receptor internalization GO:0031623 9 6 0,000 0,02748387 0,09520016 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02748387 0,09505701 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02748387 0,09491428 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02748387 0,09477198 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02748387 0,0946301 ! protein deubiquitination GO:0016579 8 6 0,000 0,02748387 0,09448865 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02748387 0,09434762 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02748387 0,09420702 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02748387 0,09406683 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02748387 0,09392706 ! midbrain development GO:0030901 6 6 0,000 0,02748387 0,0937877 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02748387 0,09364875 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02748387 0,09351022 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02748387 0,0933721 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02748387 0,09323438 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02748387 0,09309707 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02748387 0,09296016 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02748387 0,09282365 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02748387 0,09268755 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02748387 0,09255184 ! adult feeding behavior GO:0008343 6 6 0,000 0,02748387 0,09241653 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02748387 0,09228162 ! blastocyst growth GO:0001832 15 6 0,000 0,02748387 0,0921471 ! pigment granule transport GO:0051904 12 6 0,000 0,02748387 0,09201297 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02748387 0,09187923 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02748387 0,09174588 ! catecholamine transport GO:0051937 7 6 0,000 0,02748387 0,09161291 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02748387 0,09148033 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02748387 0,09134813 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02748387 0,09121632 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02748387 0,09108488 ! protein prenylation GO:0018342 10 6 0,000 0,02748387 0,09095383 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02748387 0,09082314 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,02748387 0,09069284 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02748387 0,09056291 ! camera-type eye development GO:0043010 88 57 1,000 0,02871022 0,09446855 ! viral reproductive process GO:0022415 87 58 1,000 0,02964769 0,09741383 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,02964769 0,09727486 ! activation of MAPK activity GO:0000187 84 59 1,000 0,03059727 0,10024747 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,03059727 0,10010487 ! fertilization GO:0009566 68 60 1,000 0,03155885 0,10310419 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,03199142 0,10436916 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03199142 0,10422132 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03199142 0,10407391 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,03199142 0,10392691 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03199142 0,10378033 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03199142 0,10363416 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,03199142 0,1034884 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03199142 0,10334306 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,03199142 0,10319811 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03199142 0,10305358 ! reproductive behavior GO:0019098 12 7 0,000 0,03199142 0,10290945 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03199142 0,10276572 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,03199142 0,10262239 ! oligopeptide transport GO:0006857 11 7 0,000 0,03199142 0,10247946 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03199142 0,10233693 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03199142 0,1021948 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,03199142 0,10205306 ! pericardium development GO:0060039 8 7 0,000 0,03199142 0,10191171 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03199142 0,10177075 ! fibril organization GO:0043206 13 7 0,000 0,03199142 0,10163019 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,03199142 0,10149001 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03199142 0,10135021 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,03199142 0,10121081 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03199142 0,10107178 ! lipoprotein transport GO:0042953 9 7 0,000 0,03199142 0,10093313 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03199142 0,10079487 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03199142 0,10065698 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03199142 0,10051947 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03199142 0,10038234 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03199142 0,10024558 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03199142 0,10010919 ! chemosensory behavior GO:0007635 9 7 0,000 0,03199142 0,09997317 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,03199142 0,09983752 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03199142 0,09970224 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03199142 0,09956733 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03199142 0,09943278 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03199142 0,09929859 ! reflex GO:0060004 12 7 0,000 0,03199142 0,09916476 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03199142 0,0990313 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03199142 0,09889819 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03199142 0,09876544 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03199142 0,09863305 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,03199142 0,09850101 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03199142 0,09836933 ! spinal cord patterning GO:0021511 7 7 0,000 0,03199142 0,09823799 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,03199142 0,09810701 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,03199142 0,09797637 ! adrenal gland development GO:0030325 17 7 0,000 0,03199142 0,09784608 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03199142 0,09771614 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03199142 0,09758655 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03199142 0,09745729 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03199142 0,09732838 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03199142 0,09719981 ! endosome organization GO:0007032 10 7 0,000 0,03199142 0,09707158 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03199142 0,09694368 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03199142 0,09681613 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03199142 0,0966889 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03199142 0,09656201 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03199142 0,09643546 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,03199142 0,09630923 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03199142 0,09618334 ! galactose metabolic process GO:0006012 10 7 0,000 0,03199142 0,09605777 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03199142 0,09593254 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,03199142 0,09580762 ! organ growth GO:0035265 11 7 0,000 0,03199142 0,09568304 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03199142 0,09555877 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,03199142 0,09543483 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03199142 0,09531121 ! retinol metabolic process GO:0042572 9 7 0,000 0,03199142 0,09518791 ! behavioral fear response GO:0001662 13 7 0,000 0,03199142 0,09506493 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,03199142 0,09494226 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03199142 0,09481992 ! rRNA modification GO:0000154 12 7 0,000 0,03199142 0,09469788 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03199142 0,09457616 ! response to UV-B GO:0010224 11 7 0,000 0,03199142 0,09445476 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03199142 0,09433366 ! intermediate filament organization GO:0045109 11 7 0,000 0,03199142 0,09421287 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,03199142 0,0940924 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03199142 0,09397223 ! fibrinolysis GO:0042730 9 7 0,000 0,03199142 0,09385237 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,03199142 0,09373281 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03199142 0,09361356 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03199142 0,09349461 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03199142 0,09337596 ! response to tropane GO:0014073 13 7 0,000 0,03199142 0,09325761 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,03199142 0,09313956 ! melanosome localization GO:0032400 10 7 0,000 0,03199142 0,09302181 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03199142 0,09290436 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03199142 0,09278721 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03199142 0,09267035 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03199142 0,09255378 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03199142 0,09243751 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03199142 0,09232152 ! mast cell activation GO:0045576 9 7 0,000 0,03199142 0,09220583 ! multicellular organismal aging GO:0010259 11 7 0,000 0,03199142 0,09209043 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,03199142 0,09197532 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03199142 0,09186049 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03199142 0,09174595 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,03199142 0,0916317 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,03199142 0,09151773 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,03199142 0,09140404 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03199142 0,09129064 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,03199142 0,09117752 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03199142 0,09106467 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03199142 0,09095211 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03199142 0,09083982 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03199142 0,09072781 ! neuroblast proliferation GO:0007405 13 7 0,000 0,03199142 0,09061608 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03199142 0,09050462 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,03199142 0,09039343 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,03199142 0,09028252 ! diuresis GO:0030146 12 7 0,000 0,03199142 0,09017188 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03199142 0,09006151 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03199142 0,08995141 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03199142 0,08984158 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03199142 0,08973202 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03199142 0,08962272 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03199142 0,08951369 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03199142 0,08940493 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03199142 0,08929643 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03199142 0,08918819 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03199142 0,08908021 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03199142 0,0889725 ! lymph node development GO:0048535 9 7 0,000 0,03199142 0,08886504 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,03199142 0,08875785 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,03199142 0,08865091 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03199142 0,08854423 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,03199142 0,08843781 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03199142 0,08833164 ! ATP catabolic process GO:0006200 10 7 0,000 0,03199142 0,08822573 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03199142 0,08812007 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,03199142 0,08801466 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03199142 0,0879095 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03199142 0,0878046 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03199142 0,08769995 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03199142 0,08759554 ! muscle adaptation GO:0043500 12 7 0,000 0,03199142 0,08749139 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03199142 0,08738748 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03199142 0,08728381 ! retina homeostasis GO:0001895 9 7 0,000 0,03199142 0,0871804 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03199142 0,08707723 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,03199142 0,0869743 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,03199142 0,08687161 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,03199142 0,08676917 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03199142 0,08666697 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03199142 0,08656501 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03199142 0,08646328 ! homeostasis of number of cells GO:0048872 84 61 1,000 0,03253229 0,0878219 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,03451425 0,09306304 GO:0090046|regulation of transcription regulator activity, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,03451425 0,09295407 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,03451425 0,09284535 ! viral reproduction GO:0016032 92 63 1,000 0,03451425 0,09273689 ! regulation of lipase activity GO:0060191 109 63 1,000 0,03451425 0,09262868 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03647832 0,09778571 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03647832 0,09767188 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,03647832 0,0975583 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03647832 0,097445 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03647832 0,09733195 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03647832 0,09721917 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03647832 0,09710664 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03647832 0,09699438 ! phosphate transport GO:0006817 10 8 0,000 0,03647832 0,09688238 ! N-glycan processing GO:0006491 12 8 0,000 0,03647832 0,09677064 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03647832 0,09665915 ! UTP metabolic process GO:0046051 8 8 0,000 0,03647832 0,09654792 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03647832 0,09643694 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03647832 0,09632622 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,03647832 0,09621576 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03647832 0,09610555 ! succinate metabolic process GO:0006105 14 8 0,000 0,03647832 0,09599558 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03647832 0,09588588 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03647832 0,09577642 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,03647832 0,09566721 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,03647832 0,09555825 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,03647832 0,09544953 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03647832 0,09534107 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03647832 0,09523285 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03647832 0,09512488 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03647832 0,09501715 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03647832 0,09490966 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,03647832 0,09480242 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03647832 0,09469542 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03647832 0,09458866 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03647832 0,09448214 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03647832 0,09437586 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,03647832 0,09426982 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03647832 0,09416402 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03647832 0,09405845 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03647832 0,09395313 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03647832 0,09384803 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,03647832 0,09374317 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03647832 0,09363855 ! melanin metabolic process GO:0006582 12 8 0,000 0,03647832 0,09353416 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03647832 0,09343 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03647832 0,09332607 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,03647832 0,09322238 ! macrophage activation GO:0042116 12 8 0,000 0,03647832 0,09311891 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03647832 0,09301568 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03647832 0,09291267 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03647832 0,09280989 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03647832 0,09270734 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03647832 0,09260501 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,03647832 0,09250291 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03647832 0,09240104 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03647832 0,09229938 ! ruffle organization GO:0031529 11 8 0,000 0,03647832 0,09219796 ! osteoblast development GO:0002076 13 8 0,000 0,03647832 0,09209675 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,03647832 0,09199577 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03647832 0,09189501 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03647832 0,09179446 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03647832 0,09169414 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,03647832 0,09159404 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03647832 0,09149416 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03647832 0,09139449 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03647832 0,09129504 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03647832 0,09119581 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,03647832 0,09109679 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,03647832 0,09099798 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03647832 0,09089939 ! segment specification GO:0007379 10 8 0,000 0,03647832 0,09080102 ! cellular extravasation GO:0045123 11 8 0,000 0,03647832 0,09070285 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03647832 0,0906049 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,03647832 0,09050716 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03647832 0,09040963 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,03647832 0,09031232 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03647832 0,09021521 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,03647832 0,0901183 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03647832 0,09002161 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03647832 0,08992512 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03647832 0,08982884 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03647832 0,08973277 ! nucleosome disassembly GO:0006337 12 8 0,000 0,03647832 0,0896369 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03647832 0,08954124 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03647832 0,08944578 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03647832 0,08935052 ! icosanoid secretion GO:0032309 12 8 0,000 0,03647832 0,08925547 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03647832 0,08916062 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03647832 0,08906597 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03647832 0,08897152 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03647832 0,08887727 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03647832 0,08878322 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03647832 0,08868937 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,03647832 0,08859571 ! sterol catabolic process GO:0016127 9 8 0,000 0,03647832 0,08850226 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03647832 0,088409 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03647832 0,08831594 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03647832 0,08822307 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03647832 0,0881304 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03647832 0,08803792 ! prophase GO:0051324 11 8 0,000 0,03647832 0,08794564 ! S phase GO:0051320 8 8 0,000 0,03647832 0,08785355 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03647832 0,08776165 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03647832 0,08766995 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03647832 0,08757844 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03647832 0,08748711 ! hormone catabolic process GO:0042447 13 8 0,000 0,03647832 0,08739598 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03647832 0,08730504 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03647832 0,08721428 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03647832 0,08712372 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03647832 0,08703334 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03647832 0,08694315 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,03647832 0,08685315 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03647832 0,08676333 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03647832 0,0866737 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03647832 0,08658425 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03647832 0,08649499 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03647832 0,08640591 ! lamellipodium assembly GO:0030032 9 8 0,000 0,03647832 0,08631702 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03647832 0,08622831 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,03647832 0,08613977 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,03647832 0,08605143 ! B cell activation GO:0042113 104 65 1,000 0,03654215 0,08611367 ! defense response to bacterium GO:0042742 73 65 1,000 0,03654215 0,08602553 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,03654215 0,08593757 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,03966795 0,09319334 ! response to drug GO:0042493 108 69 1,000 0,04073178 0,09559499 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,04094469 0,09599672 ! telencephalon cell migration GO:0022029 16 9 0,000 0,04094469 0,09589896 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,04094469 0,0958014 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,04094469 0,09570404 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,04094469 0,09560688 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04094469 0,09550992 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,04094469 0,09541315 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,04094469 0,09531658 ! GTP metabolic process GO:0046039 9 9 0,000 0,04094469 0,0952202 ! elastic fiber assembly GO:0048251 13 9 0,000 0,04094469 0,09512402 ! social behavior GO:0035176 14 9 0,000 0,04094469 0,09502803 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,04094469 0,09493224 ! artery development GO:0060840 19 9 0,000 0,04094469 0,09483664 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,04094469 0,09474123 ! response to pain GO:0048265 16 9 0,000 0,04094469 0,09464601 ! protein complex disassembly GO:0043241 17 9 0,000 0,04094469 0,09455098 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,04094469 0,09445615 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,04094469 0,0943615 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,04094469 0,09426705 ! lung alveolus development GO:0048286 17 9 0,000 0,04094469 0,09417278 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,04094469 0,0940787 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,04094469 0,09398481 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,04094469 0,09389111 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,04094469 0,09379759 ! ventral spinal cord development GO:0021517 11 9 0,000 0,04094469 0,09370426 ! protein targeting to ER GO:0045047 19 9 0,000 0,04094469 0,09361111 ! T cell selection GO:0045058 18 9 0,000 0,04094469 0,09351815 ! endoderm development GO:0007492 12 9 0,000 0,04094469 0,09342538 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,04094469 0,09333278 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,04094469 0,09324038 ! arginine catabolic process GO:0006527 10 9 0,000 0,04094469 0,09314815 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,04094469 0,09305611 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,04094469 0,09296424 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,04094469 0,09287256 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04094469 0,09278106 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,04094469 0,09268974 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,04094469 0,0925986 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,04094469 0,09250764 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,04094469 0,09241686 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04094469 0,09232625 ! mannose metabolic process GO:0006013 9 9 0,000 0,04094469 0,09223583 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,04094469 0,09214558 ! receptor clustering GO:0043113 15 9 0,000 0,04094469 0,0920555 ! epithelial cell development GO:0002064 10 9 0,000 0,04094469 0,0919656 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,04094469 0,09187588 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,04094469 0,09178633 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,04094469 0,09169696 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,04094469 0,09160776 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,04094469 0,09151874 ! motor axon guidance GO:0008045 14 9 0,000 0,04094469 0,09142988 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,04094469 0,0913412 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,04094469 0,09125269 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,04094469 0,09116436 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,04094469 0,09107619 ! blastoderm segmentation GO:0007350 11 9 0,000 0,04094469 0,09098819 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,04094469 0,09090037 ! DNA ligation GO:0006266 14 9 0,000 0,04094469 0,09081271 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,04094469 0,09072522 ! response to amine stimulus GO:0014075 13 9 0,000 0,04094469 0,0906379 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,04094469 0,09055075 ! erythrocyte development GO:0048821 11 9 0,000 0,04094469 0,09046377 ! renal water homeostasis GO:0003091 14 9 0,000 0,04094469 0,09037695 ! postreplication repair GO:0006301 11 9 0,000 0,04094469 0,0902903 ! mRNA cleavage GO:0006379 13 9 0,000 0,04094469 0,09020381 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,04094469 0,09011749 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,04094469 0,09003134 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,04094469 0,08994535 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,04094469 0,08985952 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,04094469 0,08977386 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,04094469 0,08968836 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,04094469 0,08960303 ! acid secretion GO:0046717 14 9 0,000 0,04094469 0,08951785 ! musculoskeletal movement GO:0050881 11 9 0,000 0,04094469 0,08943284 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,04094469 0,08934799 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,04094469 0,0892633 ! purine base metabolic process GO:0006144 18 9 0,000 0,04094469 0,08917877 ! oocyte differentiation GO:0009994 12 9 0,000 0,04094469 0,0890944 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,04094469 0,08901019 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,04094469 0,08892614 ! spleen development GO:0048536 15 9 0,000 0,04094469 0,08884224 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,04094469 0,08875851 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,04094469 0,08867493 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,04094469 0,08859151 ! detection of calcium ion GO:0005513 13 9 0,000 0,04094469 0,08850825 ! blastocyst formation GO:0001825 12 9 0,000 0,04094469 0,08842515 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,04094469 0,08834219 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,04094469 0,0882594 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,04094469 0,08817676 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,04094469 0,08809427 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04094469 0,08801194 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,04094469 0,08792977 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,04094469 0,08784774 ! prepulse inhibition GO:0060134 14 9 0,000 0,04094469 0,08776587 ! embryonic placenta development GO:0001892 12 9 0,000 0,04094469 0,08768415 ! insulin secretion GO:0030073 17 9 0,000 0,04094469 0,08760259 ! sequestering of metal ion GO:0051238 11 9 0,000 0,04094469 0,08752117 ! response to nicotine GO:0035094 16 9 0,000 0,04094469 0,08743991 ! establishment of cell polarity GO:0030010 12 9 0,000 0,04094469 0,08735879 ! nucleus localization GO:0051647 15 9 0,000 0,04094469 0,08727783 ! regulation of synapse organization GO:0050807 12 9 0,000 0,04094469 0,08719702 ! eye development GO:0001654 111 70 1,000 0,04180636 0,0889497 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,04180636 0,08886749 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 1,000 0,04180636 0,08878543 ! regulation of catabolic process GO:0009894 106 70 1,000 0,04180636 0,08870353 ! muscle cell differentiation GO:0042692 104 71 1,000 0,04289156 0,09092221 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,04289156 0,09083849 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,04398728 0,09307336 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,04398728 0,09298781 ! tube morphogenesis GO:0035239 118 73 1,000 0,04509338 0,09523855 ! mitochondrion organization GO:0007005 104 73 1,000 0,04509338 0,09515117 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,0453906 0,09569055 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,0453906 0,09560292 ! neuron fate specification GO:0048665 11 10 0,000 0,0453906 0,09551545 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,0453906 0,09542814 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,0453906 0,09534099 ! thyroid gland development GO:0030878 19 10 0,000 0,0453906 0,095254 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,0453906 0,09516717 ! synapsis GO:0007129 13 10 0,000 0,0453906 0,0950805 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,0453906 0,09499398 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,0453906 0,09490762 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,0453906 0,09482142 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,0453906 0,09473538 ! sulfate transport GO:0008272 12 10 0,000 0,0453906 0,09464949 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,0453906 0,09456375 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,0453906 0,09447818 ! androgen metabolic process GO:0008209 13 10 0,000 0,0453906 0,09439275 ! phospholipid efflux GO:0033700 16 10 0,000 0,0453906 0,09430748 ! hippocampus development GO:0021766 19 10 0,000 0,0453906 0,09422237 ! blood vessel remodeling GO:0001974 21 10 0,000 0,0453906 0,09413741 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,0453906 0,0940526 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,0453906 0,09396794 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,0453906 0,09388344 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,0453906 0,09379909 ! pathogenesis GO:0009405 13 10 0,000 0,0453906 0,09371489 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,0453906 0,09363084 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0453906 0,09354694 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,0453906 0,09346319 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,0453906 0,09337959 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,0453906 0,09329614 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,0453906 0,09321284 ! melanocyte differentiation GO:0030318 15 10 0,000 0,0453906 0,09312969 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,0453906 0,09304669 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,0453906 0,09296383 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0453906 0,09288113 ! B cell proliferation GO:0042100 14 10 0,000 0,0453906 0,09279856 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,0453906 0,09271615 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,0453906 0,09263388 ! forebrain cell migration GO:0021885 17 10 0,000 0,0453906 0,09255176 ! lipid digestion GO:0044241 15 10 0,000 0,0453906 0,09246978 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,0453906 0,09238795 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,0453906 0,09230626 ! UV protection GO:0009650 14 10 0,000 0,0453906 0,09222472 ! entry into host cell GO:0030260 20 10 0,000 0,0453906 0,09214332 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,0453906 0,09206207 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,0453906 0,09198096 ! negative regulation of ossification GO:0030279 19 10 0,000 0,0453906 0,09189999 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,0453906 0,09181916 ! regulation of bone resorption GO:0045124 24 10 0,000 0,0453906 0,09173848 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,0453906 0,09165793 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,0453906 0,09157753 ! regulation of organ growth GO:0046620 11 10 0,000 0,0453906 0,09149727 ! response to dsRNA GO:0043331 18 10 0,000 0,0453906 0,09141715 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,0453906 0,09133717 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0453906 0,09125733 ! embryonic axis specification GO:0000578 12 10 0,000 0,0453906 0,09117763 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,0453906 0,09109807 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,0453906 0,09101864 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,0453906 0,09093936 ! cranial nerve development GO:0021545 12 10 0,000 0,0453906 0,09086021 ! fucose catabolic process GO:0019317 16 10 0,000 0,0453906 0,0907812 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,0453906 0,09070233 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,0453906 0,0906236 ! protein sumoylation GO:0016925 12 10 0,000 0,0453906 0,090545 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,0453906 0,09046654 ! zymogen activation GO:0031638 14 10 0,000 0,0453906 0,09038821 ! salivary gland development GO:0007431 22 10 0,000 0,0453906 0,09031002 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0453906 0,09023197 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,0453906 0,09015405 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,0453906 0,09007626 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,0453906 0,08999861 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,0453906 0,08992109 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,0453906 0,0898437 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0453906 0,08976645 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,0453906 0,08968933 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,0453906 0,08961235 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,0453906 0,08953549 ! detection of bacterium GO:0016045 10 10 0,000 0,0453906 0,08945877 ! embryonic gut development GO:0048566 11 10 0,000 0,0453906 0,08938218 ! activation of innate immune response GO:0002218 10 10 0,000 0,0453906 0,08930572 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,0453906 0,08922939 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,0453906 0,08915319 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,0453906 0,08907712 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,0453906 0,08900118 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,0453906 0,08892537 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,0453906 0,08884969 ! protein import into nucleus GO:0006606 118 74 1,000 0,04620976 0,09037623 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,04620976 0,09029945 ! nuclear import GO:0051170 121 75 1,000 0,0473363 0,09242231 ! regulation of DNA binding GO:0051101 119 77 1,000 0,04961938 0,09679777 ! gland development GO:0048732 148 77 1,000 0,04961938 0,09671574 ! rRNA transcription GO:0009303 17 11 0,000 0,04981616 0,09701708 ! respiratory burst GO:0045730 14 11 0,000 0,04981616 0,096935 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,04981616 0,09685306 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,04981616 0,09677126 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,04981616 0,09668959 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,04981616 0,09660807 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,04981616 0,09652668 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,04981616 0,09644543 ! RNA polyadenylation GO:0043631 19 11 0,000 0,04981616 0,09636431 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,04981616 0,09628334 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,04981616 0,09620249 ! mating GO:0007618 14 11 0,000 0,04981616 0,09612179 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,04981616 0,09604122 ! T cell proliferation GO:0042098 20 11 0,000 0,04981616 0,09596078 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,04981616 0,09588048 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,04981616 0,09580031 ! bone resorption GO:0045453 16 11 0,000 0,04981616 0,09572028 ! regulated secretory pathway GO:0045055 14 11 0,000 0,04981616 0,09564038 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,04981616 0,09556061 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,04981616 0,09548097 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,04981616 0,09540147 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,04981616 0,0953221 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,04981616 0,09524287 ! syncytium formation GO:0006949 15 11 0,000 0,04981616 0,09516376 ! plasma membrane organization GO:0007009 18 11 0,000 0,04981616 0,09508479 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,04981616 0,09500595 ! focal adhesion formation GO:0048041 24 11 0,000 0,04981616 0,09492723 ! mitotic spindle organization GO:0007052 15 11 0,000 0,04981616 0,09484865 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,04981616 0,0947702 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,04981616 0,09469188 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,04981616 0,09461368 ! adult heart development GO:0007512 11 11 0,000 0,04981616 0,09453562 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,04981616 0,09445768 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,04981616 0,09437988 ! temperature homeostasis GO:0001659 16 11 0,000 0,04981616 0,0943022 ! L-glutamate transport GO:0015813 16 11 0,000 0,04981616 0,09422465 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,04981616 0,09414722 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,04981616 0,09406993 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,04981616 0,09399276 ! protein homotetramerization GO:0051289 18 11 0,000 0,04981616 0,09391571 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,04981616 0,0938388 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,04981616 0,093762 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,04981616 0,09368534 ! vasoconstriction GO:0042310 15 11 0,000 0,04981616 0,0936088 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,04981616 0,09353238 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,04981616 0,09345609 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,04981616 0,09337993 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,04981616 0,09330388 ! ribosome assembly GO:0042255 13 11 0,000 0,04981616 0,09322797 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,04981616 0,09315217 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,04981616 0,0930765 ! chromatin silencing GO:0006342 19 11 0,000 0,04981616 0,09300095 ! T cell homeostasis GO:0043029 20 11 0,000 0,04981616 0,09292552 ! regulation of isotype switching GO:0045191 19 11 0,000 0,04981616 0,09285022 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,04981616 0,09277504 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,04981616 0,09269998 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,04981616 0,09262504 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,04981616 0,09255022 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,04981616 0,09247552 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,04981616 0,09240094 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,04981616 0,09232649 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,04981616 0,09225215 ! male genitalia development GO:0030539 13 11 0,000 0,04981616 0,09217793 ! cholesterol efflux GO:0033344 19 11 0,000 0,04981616 0,09210383 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,04981616 0,09202986 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,04981616 0,091956 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,04981616 0,09188225 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,04981616 0,09180863 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,04981616 0,09173512 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,04981616 0,09166174 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,04981616 0,09158847 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,04981616 0,09151531 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,04981616 0,09144227 ! lysogeny GO:0030069 18 11 0,000 0,04981616 0,09136935 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,04981616 0,09129655 ! acrosome reaction GO:0007340 13 11 0,000 0,04981616 0,09122386 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,04981616 0,09115129 ! T cell activation GO:0042110 134 79 1,000 0,05194171 0,09496498 ! chromatin assembly GO:0031497 102 80 1,000 0,05311732 0,0970372 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 1,000 0,05311732 0,09696019 ! lactation GO:0007595 20 12 0,000 0,05422145 0,09889718 ! reproductive cellular process GO:0048610 14 12 0,000 0,05422145 0,09881882 ! tRNA modification GO:0006400 14 12 0,000 0,05422145 0,09874057 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,05422145 0,09866246 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,05422145 0,09858446 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,05422145 0,09850659 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,05422145 0,09842884 ! non-recombinational repair GO:0000726 19 12 0,000 0,05422145 0,09835122 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,05422145 0,09827372 ! peroxisomal transport GO:0043574 21 12 0,000 0,05422145 0,09819634 ! cartilage condensation GO:0001502 18 12 0,000 0,05422145 0,09811908 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,05422145 0,09804194 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,05422145 0,09796492 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,05422145 0,09788803 ! heart looping GO:0001947 15 12 0,000 0,05422145 0,09781125 ! palate development GO:0060021 15 12 0,000 0,05422145 0,0977346 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,05422145 0,09765806 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,05422145 0,09758165 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,05422145 0,09750535 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,05422145 0,09742918 ! arginine metabolic process GO:0006525 13 12 0,000 0,05422145 0,09735312 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,05422145 0,09727718 ! methionine metabolic process GO:0006555 13 12 0,000 0,05422145 0,09720136 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,05422145 0,09712566 ! Golgi organization GO:0007030 18 12 0,000 0,05422145 0,09705007 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,05422145 0,09697461 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,05422145 0,09689926 ! monoamine transport GO:0015844 13 12 0,000 0,05422145 0,09682403 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05422145 0,09674891 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,05422145 0,09667391 ! L-amino acid transport GO:0015807 20 12 0,000 0,05422145 0,09659903 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,05422145 0,09652426 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,05422145 0,09644961 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,05422145 0,09637507 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05422145 0,09630065 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,05422145 0,09622635 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,05422145 0,09615216 ! cerebellum development GO:0021549 13 12 0,000 0,05422145 0,09607808 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,05422145 0,09600412 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,05422145 0,09593027 ! histone methylation GO:0016571 15 12 0,000 0,05422145 0,09585653 ! autonomic nervous system development GO:0048483 23 12 0,000 0,05422145 0,09578291 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,05422145 0,0957094 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,05422145 0,095636 ! regulation of epidermis development GO:0045682 17 12 0,000 0,05422145 0,09556272 ! intestinal absorption GO:0050892 19 12 0,000 0,05422145 0,09548955 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,05422145 0,09541649 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,05422145 0,09534354 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,05422145 0,0952707 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,05422145 0,09519797 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,05422145 0,09512536 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,05422145 0,09505286 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,05422145 0,09498046 ! microspike assembly GO:0030035 23 12 0,000 0,05422145 0,09490818 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,05422145 0,094836 ! response to cold GO:0009409 14 12 0,000 0,05422145 0,09476394 ! mRNA transport GO:0051028 121 81 1,000 0,0543024 0,09483335 ! regulation of neurological system process GO:0031644 122 81 1,000 0,0543024 0,0947614 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,0543024 0,09468956 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,05549685 0,09669906 GO:0060348|bone development, ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,05791341 0,10083334 ! protein-DNA complex assembly GO:0065004 107 84 1,000 0,05791341 0,10075706 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,05860658 0,10188596 ! cGMP metabolic process GO:0046068 16 13 0,000 0,05860658 0,10180901 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,05860658 0,10173217 ! water transport GO:0006833 17 13 0,000 0,05860658 0,10165545 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,05860658 0,10157884 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,05860658 0,10150235 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,05860658 0,10142598 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,05860658 0,10134972 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,05860658 0,10127357 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,05860658 0,10119754 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,05860658 0,10112162 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,05860658 0,10104582 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,05860658 0,10097013 ! response to hexose stimulus GO:0009746 19 13 0,000 0,05860658 0,10089455 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,05860658 0,10081909 ! glutamate metabolic process GO:0006536 18 13 0,000 0,05860658 0,10074374 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,05860658 0,1006685 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,05860658 0,10059338 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,05860658 0,10051836 ! NAD metabolic process GO:0019674 21 13 0,000 0,05860658 0,10044346 ! exocrine system development GO:0035272 27 13 0,000 0,05860658 0,10036867 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,05860658 0,10029399 ! bone mineralization GO:0030282 15 13 0,000 0,05860658 0,10021942 ! regulation of exocytosis GO:0017157 17 13 0,000 0,05860658 0,10014497 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,05860658 0,10007062 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,05860658 0,09999638 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,05860658 0,09992226 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,05860658 0,09984824 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,05860658 0,09977433 ! genitalia development GO:0048806 15 13 0,000 0,05860658 0,09970054 ! cellular pigmentation GO:0033059 24 13 0,000 0,05860658 0,09962685 ! tissue regeneration GO:0042246 21 13 0,000 0,05860658 0,09955327 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,05860658 0,0994798 ! cofactor transport GO:0051181 19 13 0,000 0,05860658 0,09940643 ! NADP metabolic process GO:0006739 18 13 0,000 0,05860658 0,09933318 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,05860658 0,09926003 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,05860658 0,09918699 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05860658 0,09911406 ! gas transport GO:0015669 18 13 0,000 0,05860658 0,09904124 ! regulation of RNA stability GO:0043487 28 13 0,000 0,05860658 0,09896852 ! heme biosynthetic process GO:0006783 20 13 0,000 0,05860658 0,09889591 ! regulation of axon extension GO:0030516 23 13 0,000 0,05860658 0,0988234 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,05860658 0,09875101 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,05860658 0,09867871 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,05860658 0,09860653 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,05860658 0,09853445 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,05860658 0,09846247 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,05860658 0,0983906 ! transcription initiation GO:0006352 118 85 1,000 0,0591353 0,09920582 ! regulation of membrane potential GO:0042391 128 85 1,000 0,0591353 0,09913352 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,0591353 0,09906132 ! nucleosome organization GO:0034728 114 87 1,000 0,06160577 0,10312465 ! cellular defense response GO:0006968 102 87 1,000 0,06160577 0,10304965 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,06160577 0,10297476 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,06285414 0,10498512 ! establishment of RNA localization GO:0051236 128 88 1,000 0,06285414 0,10490893 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,06297161 0,1050288 ! superoxide anion generation GO:0042554 18 14 0,000 0,06297161 0,10495269 ! neuron maturation GO:0042551 21 14 0,000 0,06297161 0,10487669 ! regulation of S phase GO:0033261 18 14 0,000 0,06297161 0,10480081 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,06297161 0,10472503 ! myotube differentiation GO:0014902 21 14 0,000 0,06297161 0,10464936 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,06297161 0,1045738 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,06297161 0,10449835 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,06297161 0,10442301 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,06297161 0,10434778 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,06297161 0,10427265 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,06297161 0,10419764 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,06297161 0,10412273 ! gene silencing by RNA GO:0031047 20 14 0,000 0,06297161 0,10404793 ! response to cAMP GO:0051591 19 14 0,000 0,06297161 0,10397323 ! limbic system development GO:0021761 25 14 0,000 0,06297161 0,10389865 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,06297161 0,10382417 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,06297161 0,1037498 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,06297161 0,10367553 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,06297161 0,10360137 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,06297161 0,10352732 ! glycine metabolic process GO:0006544 22 14 0,000 0,06297161 0,10345337 ! pituitary gland development GO:0021983 23 14 0,000 0,06297161 0,10337952 ! lysosomal transport GO:0007041 20 14 0,000 0,06297161 0,10330579 ! regulation of heart rate GO:0002027 23 14 0,000 0,06297161 0,10323216 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,06297161 0,10315863 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,06297161 0,10308521 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,06297161 0,10301189 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,06297161 0,10293867 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,06297161 0,10286556 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,06297161 0,10279256 ! axon cargo transport GO:0008088 27 14 0,000 0,06297161 0,10271966 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,06297161 0,10264686 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,06297161 0,10257416 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,06297161 0,10250157 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,06297161 0,10242908 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06297161 0,10235669 ! mRNA splice site selection GO:0006376 26 14 0,000 0,06297161 0,1022844 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,06297161 0,10221222 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,06297161 0,10214014 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,06297161 0,10206816 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,06297161 0,10199628 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,06297161 0,1019245 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,06297161 0,10185282 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,06297161 0,10178125 ! muscle maintenance GO:0046716 19 14 0,000 0,06297161 0,10170977 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,06297161 0,1016384 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,06297161 0,10156712 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,06297161 0,10149595 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,06297161 0,10142487 ! cell killing GO:0001906 20 14 0,000 0,06297161 0,10135389 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,06297161 0,10128302 ! cilium assembly GO:0042384 20 14 0,000 0,06297161 0,10121224 ! peptide hormone secretion GO:0030072 23 14 0,000 0,06297161 0,10114156 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,06411112 0,10289991 ! reproductive developmental process GO:0003006 127 89 1,000 0,06411112 0,10282815 ! leukocyte differentiation GO:0002521 143 90 1,000 0,06537661 0,10478481 ! RNA localization GO:0006403 135 91 1,000 0,0666505 0,1067522 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,06731666 0,10774414 ! positive regulation of cell size GO:0045793 20 15 0,000 0,06731666 0,10766921 ! metencephalon development GO:0022037 19 15 0,000 0,06731666 0,10759439 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,06731666 0,10751967 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,06731666 0,10744506 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,06731666 0,10737054 ! skin development GO:0043588 25 15 0,000 0,06731666 0,10729614 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,06731666 0,10722183 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,06731666 0,10714763 ! lipid phosphorylation GO:0046834 23 15 0,000 0,06731666 0,10707353 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,06731666 0,10699953 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,06731666 0,10692564 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,06731666 0,10685185 ! bile acid metabolic process GO:0008206 22 15 0,000 0,06731666 0,10677815 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,06731666 0,10670457 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,06731666 0,10663108 ! adult walking behavior GO:0007628 25 15 0,000 0,06731666 0,10655769 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,06731666 0,1064844 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,06731666 0,10641122 ! myoblast differentiation GO:0045445 27 15 0,000 0,06731666 0,10633813 ! centrosome cycle GO:0007098 16 15 0,000 0,06731666 0,10626515 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,06731666 0,10619227 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,06731666 0,10611948 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,06731666 0,1060468 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,06731666 0,10597421 ! cerebral cortex development GO:0021987 29 15 0,000 0,06731666 0,10590173 ! response to osmotic stress GO:0006970 22 15 0,000 0,06731666 0,10582934 ! vesicle coating GO:0006901 25 15 0,000 0,06731666 0,10575705 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,06731666 0,10568486 ! DNA integration GO:0015074 22 15 0,000 0,06731666 0,10561277 ! peptide secretion GO:0002790 27 15 0,000 0,06731666 0,10554078 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,06731666 0,10546889 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,06731666 0,10539709 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,06731666 0,10532539 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,06731666 0,10525379 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,06731666 0,10518229 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,06731666 0,10511088 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,06731666 0,10503957 ! biomineral formation GO:0031214 18 15 0,000 0,06731666 0,10496836 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,06731666 0,10489724 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,06731666 0,10482622 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,06731666 0,10475529 ! dopamine metabolic process GO:0042417 30 15 0,000 0,06731666 0,10468447 ! organic cation transport GO:0015695 19 15 0,000 0,06731666 0,10461373 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,06731666 0,1045431 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,06731666 0,10447255 ! defense response to virus GO:0051607 27 15 0,000 0,06731666 0,10440211 ! peptide hormone processing GO:0016486 19 15 0,000 0,06731666 0,10433176 ! protein secretion GO:0009306 27 16 0,000 0,07164181 0,11096038 ! hormone secretion GO:0046879 25 16 0,000 0,07164181 0,11088571 ! bone remodeling GO:0046849 24 16 0,000 0,07164181 0,11081114 ! endothelial cell migration GO:0043542 22 16 0,000 0,07164181 0,11073667 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,07164181 0,1106623 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07164181 0,11058803 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,07164181 0,11051386 ! glial cell development GO:0021782 24 16 0,000 0,07164181 0,11043979 ! patterning of blood vessels GO:0001569 24 16 0,000 0,07164181 0,11036582 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,07164181 0,11029194 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,07164181 0,11021817 ! protein polyubiquitination GO:0000209 26 16 0,000 0,07164181 0,11014449 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,07164181 0,11007092 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,07164181 0,10999744 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,07164181 0,10992406 ! fructose metabolic process GO:0006000 20 16 0,000 0,07164181 0,10985078 ! regulation of protein binding GO:0043393 27 16 0,000 0,07164181 0,10977759 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,07164181 0,1097045 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,07164181 0,10963151 ! protein export from nucleus GO:0006611 24 16 0,000 0,07164181 0,10955862 ! negative regulation of immune response GO:0050777 28 16 0,000 0,07164181 0,10948582 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,07164181 0,10941312 ! DNA replication initiation GO:0006270 25 16 0,000 0,07164181 0,10934052 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,07164181 0,10926801 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,07164181 0,1091956 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,07164181 0,10912329 ! diencephalon development GO:0021536 25 16 0,000 0,07164181 0,10905107 ! oogenesis GO:0048477 23 16 0,000 0,07164181 0,10897894 ! neural crest cell migration GO:0001755 24 16 0,000 0,07164181 0,10890692 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,07164181 0,10883498 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,07164181 0,10876314 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,07164181 0,1086914 ! steroid catabolic process GO:0006706 22 16 0,000 0,07164181 0,10861975 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,07164181 0,1085482 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,07164181 0,10847674 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,07164181 0,10840537 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,07164181 0,1083341 ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,07164181 0,10826292 ! nerve development GO:0021675 18 16 0,000 0,07164181 0,10819183 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,07164181 0,10812084 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,07164181 0,10804994 ! negative regulation of translation GO:0017148 22 16 0,000 0,07164181 0,10797914 ! regulation of binding GO:0051098 151 95 1,000 0,07182811 0,10818903 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,07314251 0,11009671 ! in utero embryonic development GO:0001701 147 96 1,000 0,07314251 0,1100247 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,07314251 0,10995279 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,07314251 0,10988097 ! protein amino acid glycosylation GO:0006486 134 97 1,000 0,07446471 0,11179427 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,07594715 0,11394549 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,07594715 0,11387121 ! negative regulation of defense response GO:0031348 19 17 0,000 0,07594715 0,11379703 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,07594715 0,11372294 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,07594715 0,11364895 ! glycerol metabolic process GO:0006071 20 17 0,000 0,07594715 0,11357506 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,07594715 0,11350126 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,07594715 0,11342756 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,07594715 0,11335395 ! signal complex assembly GO:0007172 29 17 0,000 0,07594715 0,11328044 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,07594715 0,11320702 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,07594715 0,1131337 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,07594715 0,11306048 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,07594715 0,11298735 ! memory GO:0007613 25 17 0,000 0,07594715 0,11291431 ! keratinization GO:0031424 17 17 0,000 0,07594715 0,11284137 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,07594715 0,11276852 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,07594715 0,11269577 ! retinoid metabolic process GO:0001523 22 17 0,000 0,07594715 0,11262311 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,07594715 0,11255054 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,07594715 0,11247807 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,07594715 0,11240569 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,07594715 0,1123334 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,07594715 0,11226121 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,07594715 0,11218911 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,07594715 0,1121171 ! membrane budding GO:0006900 29 17 0,000 0,07594715 0,11204518 ! heme metabolic process GO:0042168 27 17 0,000 0,07594715 0,11197336 ! actin filament bundle formation GO:0051017 26 17 0,000 0,07594715 0,11190163 ! neuromuscular junction development GO:0007528 23 17 0,000 0,07594715 0,11182999 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,07594715 0,11175844 ! body fluid secretion GO:0007589 27 17 0,000 0,07594715 0,11168698 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,07594715 0,11161562 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,07594715 0,11154434 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,07594715 0,11147316 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,07594715 0,11140207 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,07594715 0,11133106 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,07594715 0,11126015 ! synaptogenesis GO:0007416 24 17 0,000 0,07594715 0,11118933 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,07594715 0,1111186 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,07594715 0,11104796 ! cell-cell junction organization GO:0045216 25 17 0,000 0,07594715 0,11097741 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,07594715 0,11090694 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,07594715 0,11083657 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,07594715 0,11076629 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,07594715 0,1106961 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,07594715 0,11062599 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,07594715 0,11055597 ! protein import GO:0017038 156 99 1,000 0,07713212 0,11220991 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,07713212 0,11213898 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,07847713 0,11402237 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,07847713 0,11395038 ! protein localization in organelle GO:0033365 161 100 1,000 0,07847713 0,11387849 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,08023276 0,11635268 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,08023276 0,11627937 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,08023276 0,11620614 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,08023276 0,11613301 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,08023276 0,11605997 ! cAMP metabolic process GO:0046058 33 18 0,000 0,08023276 0,11598702 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,08023276 0,11591417 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,08023276 0,1158414 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,08023276 0,11576873 ! axis specification GO:0009798 26 18 0,000 0,08023276 0,11569615 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,08023276 0,11562366 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,08023276 0,11555126 ! pancreas development GO:0031016 26 18 0,000 0,08023276 0,11547895 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,08023276 0,11540673 ! glutamine metabolic process GO:0006541 23 18 0,000 0,08023276 0,1153346 ! response to retinoic acid GO:0032526 25 18 0,000 0,08023276 0,11526256 ! pigmentation during development GO:0048066 31 18 0,000 0,08023276 0,11519061 ! central nervous system neuron development GO:0021954 30 18 0,000 0,08023276 0,11511875 ! fucose metabolic process GO:0006004 26 18 0,000 0,08023276 0,11504698 ! response to fungus GO:0009620 19 18 0,000 0,08023276 0,1149753 ! peptide cross-linking GO:0018149 31 18 0,000 0,08023276 0,11490371 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,08023276 0,11483221 ! heart process GO:0003015 27 18 0,000 0,08023276 0,11476079 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,08023276 0,11468947 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,08023276 0,11461823 ! visual learning GO:0008542 35 18 0,000 0,08023276 0,11454709 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,08023276 0,11447603 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,08023276 0,11440506 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,08023276 0,11433417 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,08023276 0,11426338 ! vitamin transport GO:0051180 24 18 0,000 0,08023276 0,11419267 ! hormone transport GO:0009914 27 18 0,000 0,08023276 0,11412205 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,08023276 0,11405152 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,08023276 0,11398107 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,08023276 0,11391071 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,08023276 0,11384044 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,08023276 0,11377026 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,08023276 0,11370016 ! regulation of glucose import GO:0046324 21 18 0,000 0,08023276 0,11363014 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,08023276 0,11356022 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,08023276 0,11349038 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,08023276 0,11342062 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,08449875 0,11937784 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,08449875 0,11930455 ! positive regulation of ossification GO:0045778 30 19 0,000 0,08449875 0,11923136 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,08449875 0,11915826 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,08449875 0,11908524 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,08449875 0,11901232 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,08449875 0,11893948 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,08449875 0,11886674 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,08449875 0,11879408 ! regeneration GO:0031099 32 19 0,000 0,08449875 0,11872151 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,08449875 0,11864903 ! response to alkaloid GO:0043279 32 19 0,000 0,08449875 0,11857664 ! sensory perception of taste GO:0050909 23 19 0,000 0,08449875 0,11850434 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,08449875 0,11843213 ! smooth muscle contraction GO:0006939 36 19 0,000 0,08449875 0,11836 ! peroxisome organization GO:0007031 29 19 0,000 0,08449875 0,11828796 ! digestive system process GO:0022600 30 19 0,000 0,08449875 0,11821601 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,08449875 0,11814414 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,08449875 0,11807237 ! response to vitamin A GO:0033189 26 19 0,000 0,08449875 0,11800068 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,08449875 0,11792908 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,08449875 0,11785756 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,08449875 0,11778613 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,08449875 0,11771479 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,08449875 0,11764353 ! plasma membrane fusion GO:0045026 23 19 0,000 0,08449875 0,11757236 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,08449875 0,11750128 ! cytolysis GO:0019835 20 19 0,000 0,08449875 0,11743028 ! renal system process GO:0003014 35 19 0,000 0,08449875 0,11735937 ! vasodilation GO:0042311 33 19 0,000 0,08449875 0,11728854 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,08449875 0,1172178 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,08449875 0,11714715 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,08449875 0,11707658 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,08449875 0,11700609 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,08449875 0,11693569 ! sarcomere organization GO:0045214 23 19 0,000 0,08449875 0,11686537 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,08449875 0,11679514 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,08449875 0,116725 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,08449875 0,11665493 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,08449875 0,11658495 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,08449875 0,11651506 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,08449875 0,11644525 ! protein stabilization GO:0050821 26 19 0,000 0,08449875 0,11637552 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,08874519 0,12215077 ! iron ion transport GO:0006826 37 20 0,000 0,08874519 0,12207771 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,08874519 0,12200474 GO:0006044|N-acetylglucosamine metabolic process, ! response to vitamin GO:0033273 29 20 0,000 0,08874519 0,12193186 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,08874519 0,12185906 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,08874519 0,12178636 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,08874519 0,12171373 ! spinal cord development GO:0021510 31 20 0,000 0,08874519 0,1216412 ! response to ethanol GO:0045471 37 20 0,000 0,08874519 0,12156875 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,08874519 0,12149639 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,08874519 0,12142411 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,08874519 0,12135192 ! chromosome condensation GO:0030261 31 20 0,000 0,08874519 0,12127982 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,08874519 0,1212078 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,08874519 0,12113587 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,08874519 0,12106402 ! pallium development GO:0021543 38 20 0,000 0,08874519 0,12099225 ! DNA modification GO:0006304 28 20 0,000 0,08874519 0,12092058 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,08874519 0,12084898 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,08874519 0,12077748 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,08874519 0,12070605 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,08874519 0,12063471 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,08874519 0,12056346 ! collagen catabolic process GO:0030574 25 20 0,000 0,08874519 0,12049229 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,08874519 0,1204212 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,08874519 0,1203502 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,08874519 0,12027928 ! alditol metabolic process GO:0019400 24 20 0,000 0,08874519 0,12020844 ! actin filament-based movement GO:0030048 34 20 0,000 0,08874519 0,12013769 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,09297217 0,12578588 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,09297217 0,12571194 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,09297217 0,12563807 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,09297217 0,1255643 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,09297217 0,12549061 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,09297217 0,12541701 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,09297217 0,12534349 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,09297217 0,12527007 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,09297217 0,12519672 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,09297217 0,12512347 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,09297217 0,12505029 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,09297217 0,12497721 ! phototransduction GO:0007602 25 21 0,000 0,09297217 0,12490421 ! visual behavior GO:0007632 39 21 0,000 0,09297217 0,12483129 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,09297217 0,12475846 ! ovarian follicle development GO:0001541 30 21 0,000 0,09297217 0,12468572 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,09297217 0,12461305 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,09297217 0,12454048 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,09297217 0,12446799 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,09297217 0,12439558 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,09297217 0,12432326 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,09297217 0,12425102 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,09297217 0,12417886 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,09297217 0,12410679 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,09297217 0,1240348 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,09297217 0,1239629 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,09297217 0,12389108 ! fatty acid transport GO:0015908 30 21 0,000 0,09297217 0,12381934 ! immunoglobulin production GO:0002377 33 21 0,000 0,09297217 0,12374769 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,09297217 0,12367611 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,09297217 0,12360463 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,09297217 0,12353322 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,09297217 0,12346189 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,09297217 0,12339065 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,09297217 0,12331949 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,09297217 0,12324842 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,09297217 0,12317742 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,09297217 0,12310651 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,09297217 0,12303567 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,09297217 0,12296492 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,09297217 0,12289425 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,09297217 0,12282367 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,09297217 0,12275316 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,09717979 0,12823496 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,09717979 0,12816143 ! viral genome replication GO:0019079 29 22 0,000 0,09717979 0,12808798 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,09717979 0,12801462 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,09717979 0,12794134 ! leukocyte adhesion GO:0007159 38 22 0,000 0,09717979 0,12786815 ! molting cycle process GO:0022404 40 22 0,000 0,09717979 0,12779504 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,09717979 0,12772202 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,09717979 0,12764907 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,09717979 0,12757621 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,09717979 0,12750344 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,09717979 0,12743075 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,09717979 0,12735814 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,09717979 0,12728561 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 37 22 0,000 0,09717979 0,12721316 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,09717979 0,1271408 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,09717979 0,12706852 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,09717979 0,12699632 ! regulation of behavior GO:0050795 38 22 0,000 0,09717979 0,12692421 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,09717979 0,12685217 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,09717979 0,12678022 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,09717979 0,12670835 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,09717979 0,12663656 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,09717979 0,12656485 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,09717979 0,12649322 ! blastocyst development GO:0001824 37 22 0,000 0,09717979 0,12642168 ! neural tube closure GO:0001843 33 22 0,000 0,09717979 0,12635021 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,09717979 0,12627883 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,10136814 0,13164693 ! neuron fate commitment GO:0048663 32 23 0,000 0,10136814 0,13157264 ! embryonic pattern specification GO:0009880 31 23 0,000 0,10136814 0,13149843 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,10136814 0,1314243 ! myelination GO:0042552 35 23 0,000 0,10136814 0,13135026 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,10136814 0,1312763 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,10136814 0,13120243 ! vesicle targeting GO:0006903 32 23 0,000 0,10136814 0,13112863 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,10136814 0,13105493 ! osteoblast differentiation GO:0001649 40 23 0,000 0,10136814 0,1309813 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,10136814 0,13090776 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,10136814 0,13083429 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,10136814 0,13076092 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,10136814 0,13068762 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,10136814 0,1306144 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,10136814 0,13054127 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,10136814 0,13046822 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,10136814 0,13039525 ! pentose metabolic process GO:0019321 31 23 0,000 0,10136814 0,13032237 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,10136814 0,13024956 ! spermatid development GO:0007286 33 23 0,000 0,10136814 0,13017684 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,10136814 0,13010419 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,10136814 0,13003163 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,10136814 0,12995915 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,10136814 0,12988675 ! telomere organization GO:0032200 32 23 0,000 0,10136814 0,12981443 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,10136814 0,12974219 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,10136814 0,12967003 ! regulation of amine transport GO:0051952 38 23 0,000 0,10136814 0,12959795 ! liver development GO:0001889 40 23 0,000 0,10136814 0,12952595 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,10553729 0,13477832 ! initiation of viral infection GO:0019059 42 24 0,000 0,10553729 0,13470353 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,10553729 0,13462882 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,10553729 0,13455419 ! superoxide metabolic process GO:0006801 32 24 0,000 0,10553729 0,13447964 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,10553729 0,13440518 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,10553729 0,1343308 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,10553729 0,1342565 ! vacuole organization GO:0007033 39 24 0,000 0,10553729 0,13418229 ! receptor metabolic process GO:0043112 37 24 0,000 0,10553729 0,13410815 ! neural crest cell development GO:0014032 39 24 0,000 0,10553729 0,1340341 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,10553729 0,13396013 ! primary neural tube formation GO:0014020 35 24 0,000 0,10553729 0,13388624 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,10553729 0,13381243 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,10553729 0,13373871 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,10553729 0,13366506 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,10553729 0,1335915 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,10553729 0,13351802 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,10553729 0,13344462 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,10968733 0,13861586 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,10968733 0,13853974 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,10968733 0,1384637 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,10968733 0,13838775 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,10968733 0,13831187 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,10968733 0,13823609 ! peptide transport GO:0015833 43 25 0,000 0,10968733 0,13816038 ! male gonad development GO:0008584 33 25 0,000 0,10968733 0,13808476 ! iron ion homeostasis GO:0055072 39 25 0,000 0,10968733 0,13800922 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,10968733 0,13793377 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,10968733 0,13785839 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,10968733 0,1377831 ! phospholipid transport GO:0015914 35 25 0,000 0,10968733 0,13770789 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,10968733 0,13763277 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,10968733 0,13755772 ! detection of light stimulus GO:0009583 30 25 0,000 0,10968733 0,13748276 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,10968733 0,13740788 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,10968733 0,13733308 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,11381836 0,14242776 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,11381836 0,14235031 ! translational initiation GO:0006413 43 26 0,000 0,11381836 0,14227295 ! circadian rhythm GO:0007623 42 26 0,000 0,11381836 0,14219567 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,11381836 0,14211847 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,11381836 0,14204136 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,11381836 0,14196433 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,11381836 0,14188738 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,11381836 0,14181052 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,11381836 0,14173374 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,11381836 0,14165705 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,11793045 0,14669553 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,11793045 0,14661624 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,11793045 0,14653703 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,11793045 0,1464579 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,11793045 0,14637886 ! catechol metabolic process GO:0009712 43 27 0,000 0,11793045 0,14629991 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,11793045 0,14622104 ! acute-phase response GO:0006953 42 27 0,000 0,11793045 0,14614226 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,11793045 0,14606356 ! myofibril assembly GO:0030239 36 27 0,000 0,11793045 0,14598495 GO:0055002|striated muscle cell development, ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,11793045 0,14590642 ! natural killer cell activation GO:0030101 35 27 0,000 0,11793045 0,14582798 ! lipid oxidation GO:0034440 38 27 0,000 0,11793045 0,14574962 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,11793045 0,14567134 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,11793045 0,14559315 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,11793045 0,14551504 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,11793045 0,14543702 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,11793045 0,14535908 ! gene silencing GO:0016458 41 27 0,000 0,11793045 0,14528122 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,1220237 0,15024331 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,1220237 0,15016292 ! phenol metabolic process GO:0018958 44 28 0,000 0,1220237 0,15008262 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,1220237 0,15000241 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,1220237 0,14992228 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,1220237 0,14984223 ! cell junction assembly GO:0034329 56 28 0,000 0,1220237 0,14976228 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,1220237 0,1496824 ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,1220237 0,14960261 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,1220237 0,14952291 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,1220237 0,14944329 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,1220237 0,14936376 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,1220237 0,14928431 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,1220237 0,14920495 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,1220237 0,14912567 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,1220237 0,14904647 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,1220237 0,14896736 ! ensheathment of neurons GO:0007272 43 28 0,000 0,1220237 0,14888833 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,1220237 0,14880939 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,1220237 0,14873053 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,1220237 0,14865175 ! placenta development GO:0001890 37 28 0,000 0,1220237 0,14857306 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,12609818 0,15345282 ! regulation of innate immune response GO:0045088 38 29 0,000 0,12609818 0,15337167 ! ovulation cycle process GO:0022602 41 29 0,000 0,12609818 0,1532906 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,12609818 0,15320963 ! protein targeting to membrane GO:0006612 53 29 0,000 0,12609818 0,15312873 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,12609818 0,15304793 ! mismatch repair GO:0006298 34 29 0,000 0,12609818 0,15296721 ! muscle cell development GO:0055001 38 29 0,000 0,12609818 0,15288657 ! telencephalon development GO:0021537 52 29 0,000 0,12609818 0,15280602 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,12609818 0,15272555 ! eye morphogenesis GO:0048592 51 29 0,000 0,12609818 0,15264517 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,12609818 0,15256487 ! tissue homeostasis GO:0001894 42 29 0,000 0,12609818 0,15248466 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,13015399 0,15730646 ! collagen metabolic process GO:0032963 40 30 0,000 0,13015399 0,15722384 ! organic anion transport GO:0015711 51 30 0,000 0,13015399 0,1571413 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,13015399 0,15705886 ! spliceosome assembly GO:0000245 49 30 0,000 0,13015399 0,1569765 ! spindle organization GO:0007051 37 30 0,000 0,13015399 0,15689423 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,13015399 0,15681204 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,13015399 0,15672994 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,13015399 0,15664793 ! ceramide metabolic process GO:0006672 43 30 0,000 0,13015399 0,156566 ! ovulation cycle GO:0042698 43 30 0,000 0,13015399 0,15648415 ! hindbrain development GO:0030902 45 30 0,000 0,13015399 0,1564024 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,13015399 0,15632072 ! response to heat GO:0009408 41 30 0,000 0,13015399 0,15623914 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,13015399 0,15615763 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,13015399 0,15607622 ! negative regulation of secretion GO:0051048 49 31 0,000 0,13419121 0,16083366 ! glial cell differentiation GO:0010001 55 31 0,000 0,13419121 0,16074989 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,13419121 0,16066621 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,13419121 0,16058262 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,13419121 0,16049911 ! odontogenesis GO:0042476 50 31 0,000 0,13419121 0,16041569 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,13419121 0,16033236 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,13419121 0,16024911 ! metanephros development GO:0001656 58 31 0,000 0,13419121 0,16016595 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,13419121 0,16008288 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,13419121 0,15999989 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,13419121 0,15991699 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,13419121 0,15983417 ! RNA modification GO:0009451 40 31 0,000 0,13419121 0,15975144 ! regulation of muscle development GO:0048634 48 32 0,000 0,13820992 0,1644505 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,13820992 0,16436547 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,13820992 0,16428053 ! meiosis I GO:0007127 52 32 0,000 0,13820992 0,16419567 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,13820992 0,1641109 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,13820992 0,16402622 ! peripheral nervous system development GO:0007422 53 32 0,000 0,13820992 0,16394163 ! regulation of protein stability GO:0031647 48 32 0,000 0,13820992 0,16385712 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,13820992 0,1637727 ! cytokine production GO:0001816 44 32 0,000 0,13820992 0,16368837 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,13820992 0,16360413 ! vesicle localization GO:0051648 47 32 0,000 0,13820992 0,16351997 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,14221021 0,16816631 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,14221021 0,1680799 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,14221021 0,16799357 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,14221021 0,16790733 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,14221021 0,16782118 ! sister chromatid segregation GO:0000819 46 33 0,000 0,14221021 0,16773512 ! ear morphogenesis GO:0042471 42 33 0,000 0,14221021 0,16764914 ! actomyosin structure organization GO:0031032 43 33 0,000 0,14221021 0,16756326 ! cell junction organization GO:0034330 63 33 0,000 0,14221021 0,16747746 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,14221021 0,16739175 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,14221021 0,16730613 ! nucleus organization GO:0006997 49 33 0,000 0,14221021 0,16722059 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,14221021 0,16713514 ! female gonad development GO:0008585 49 33 0,000 0,14221021 0,16704978 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,14221021 0,16696451 ! positive regulation of cell development GO:0010720 54 33 0,000 0,14221021 0,16687933 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,14221021 0,16679423 ! regulation of proteolysis GO:0030162 50 33 0,000 0,14221021 0,16670921 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,14221021 0,16662429 ! cytokinesis GO:0000910 52 33 0,000 0,14221021 0,16653945 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,14221021 0,1664547 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,14619215 0,17102846 ! mRNA catabolic process GO:0006402 48 34 0,000 0,14619215 0,17094151 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,14619215 0,17085465 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,14619215 0,17076788 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,14619215 0,1706812 ! feeding behavior GO:0007631 45 34 0,000 0,14619215 0,1705946 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,14619215 0,17050809 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,14619215 0,17042167 ! female gamete generation GO:0007292 43 34 0,000 0,14619215 0,17033534 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,14619215 0,17024909 ! aerobic respiration GO:0009060 47 34 0,000 0,14619215 0,17016293 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,14619215 0,17007686 ! embryonic organ development GO:0048568 45 34 0,000 0,14619215 0,16999088 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,14619215 0,16990498 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,15015584 0,17442345 ! Notch signaling pathway GO:0007219 56 35 0,000 0,15015584 0,17433541 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,15015584 0,17424745 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,15015584 0,17415958 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,15015584 0,17407179 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,15015584 0,1739841 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,15015584 0,17389649 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,15015584 0,17380898 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,15015584 0,17372155 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,15015584 0,17363421 ! pigment metabolic process GO:0042440 61 35 0,000 0,15015584 0,17354695 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,15410136 0,17801764 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,15410136 0,17792827 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,15410136 0,177839 ! negative regulation of binding GO:0051100 58 36 0,000 0,15410136 0,17774981 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,15410136 0,17766071 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,15410136 0,1775717 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,15410136 0,17748278 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,15410136 0,17739395 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,15802878 0,18182401 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,15802878 0,18173309 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,15802878 0,18164227 ! learning GO:0007612 67 37 0,000 0,15802878 0,18155154 ! ion transmembrane transport GO:0034220 56 37 0,000 0,15802878 0,1814609 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,15802878 0,18137035 ! regulation of protein secretion GO:0050708 51 37 0,000 0,15802878 0,18127989 ! amino acid activation GO:0043038 52 37 0,000 0,15802878 0,18118953 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,15802878 0,18109925 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,16193819 0,18548697 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,16193819 0,18539464 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,16193819 0,1853024 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,16193819 0,18521026 ! phagocytosis GO:0006909 60 38 0,000 0,16193819 0,18511821 ! mesenchymal cell development GO:0014031 64 38 0,000 0,16193819 0,18502625 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,16193819 0,18493438 ! maintenance of location in cell GO:0051651 69 38 0,000 0,16193819 0,1848426 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,16582967 0,1891906 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,16582967 0,1890968 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,16582967 0,18900309 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,16582967 0,18890948 ! male sex differentiation GO:0046661 53 39 0,000 0,16582967 0,18881596 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,16582967 0,18872253 ! chromatin remodeling GO:0006338 68 39 0,000 0,16582967 0,1886292 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,16582967 0,18853596 ! JNK cascade GO:0007254 54 39 0,000 0,16582967 0,18844281 ! developmental growth GO:0048589 62 39 0,000 0,16582967 0,18834975 ! synapse organization GO:0050808 55 39 0,000 0,16582967 0,18825678 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,1697033 0,19255925 ! response to calcium ion GO:0051592 58 40 0,000 0,1697033 0,1924643 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,1697033 0,19236944 ! regulation of tube size GO:0035150 60 40 0,000 0,1697033 0,19227468 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,1697033 0,19218001 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,1697033 0,19208543 ! peptide metabolic process GO:0006518 56 40 0,000 0,1697033 0,19199095 ! inner ear development GO:0048839 57 40 0,000 0,1697033 0,19189656 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,1697033 0,19180226 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! JAK-STAT cascade GO:0007259 53 40 0,000 0,1697033 0,19170805 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,17355917 0,19596764 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,17355917 0,19587149 ! glucose transport GO:0015758 52 41 0,000 0,17355917 0,19577543 ! endosome transport GO:0016197 71 41 0,000 0,17355917 0,19567946 ! striated muscle contraction GO:0006941 62 41 0,000 0,17355917 0,19558358 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,17355917 0,1954878 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,17355917 0,19539212 ! biopolymer methylation GO:0043414 62 41 0,000 0,17355917 0,19529652 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,17355917 0,19520102 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,17739735 0,19942029 ! cellular component disassembly GO:0022411 64 42 0,000 0,17739735 0,19932287 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,17739735 0,19922554 ! hexose transport GO:0008645 54 42 0,000 0,17739735 0,19912831 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,17739735 0,19903117 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,17739735 0,19893413 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,17739735 0,19883719 ! excretion GO:0007588 63 42 0,000 0,17739735 0,19874033 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,17739735 0,19864358 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,17739735 0,19854691 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,17739735 0,19845034 ! leukocyte migration GO:0050900 60 43 0,000 0,18121793 0,20262578 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,18121793 0,20252732 ! tRNA processing GO:0008033 49 43 0,000 0,18121793 0,20242896 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,18121793 0,20233069 ! methylation GO:0032259 64 43 0,000 0,18121793 0,20223252 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,18502097 0,20637645 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,18502097 0,20627641 ! glycolysis GO:0006096 53 44 0,000 0,18502097 0,20617647 ! regulation of action potential GO:0001508 71 44 0,000 0,18502097 0,20607663 ! regulation of ion transport GO:0043269 57 44 0,000 0,18502097 0,20597688 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,18502097 0,20587723 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,18502097 0,20577768 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,18502097 0,20567822 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,18502097 0,20557886 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,18502097 0,20547959 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,18502097 0,20538042 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,18502097 0,20528135 ! RNA catabolic process GO:0006401 64 45 0,000 0,18880657 0,20938048 ! positive regulation of defense response GO:0031349 59 45 0,000 0,18880657 0,20927958 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,18880657 0,20917877 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,18880657 0,20907805 ! cell maturation GO:0048469 60 45 0,000 0,18880657 0,20897744 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,19257481 0,21304572 ! cell redox homeostasis GO:0045454 63 46 0,000 0,19257481 0,21294329 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,19257481 0,21284097 ! regulation of ossification GO:0030278 71 46 0,000 0,19257481 0,21273874 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,19257481 0,21263661 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,19632575 0,21667429 ! viral infectious cycle GO:0019058 71 47 0,000 0,19632575 0,21657037 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,19632575 0,21646655 ! endocrine system development GO:0035270 83 47 0,000 0,19632575 0,21636283 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,19632575 0,21625921 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,19632575 0,21615568 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,19632575 0,21605226 ! chloride transport GO:0006821 67 48 0,000 0,20005948 0,22005586 ! response to temperature stimulus GO:0009266 62 48 0,000 0,20005948 0,21995067 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,20005948 0,21984558 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,20005948 0,21974059 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,20005948 0,21963571 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,20005948 0,21953092 ! regulation of endocytosis GO:0030100 63 48 0,000 0,20005948 0,21942623 ! nuclear export GO:0051168 69 48 0,000 0,20005948 0,21932164 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,20005948 0,21921715 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,20005948 0,21911276 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,20377608 0,2230771 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,20377608 0,22297097 ! sensory perception of smell GO:0007608 61 49 0,000 0,20377608 0,22286495 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,20377608 0,22275902 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,20377608 0,2226532 ! RNA elongation GO:0006354 62 49 0,000 0,20377608 0,22254748 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,20377608 0,22244185 ! germ cell development GO:0007281 68 49 0,000 0,20377608 0,22233633 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,20377608 0,22223091 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,20377608 0,22212558 ! cartilage development GO:0051216 70 49 0,000 0,20377608 0,22202036 ! maintenance of location GO:0051235 84 49 0,000 0,20377608 0,22191524 ! regulation of actin filament length GO:0030832 72 50 0,000 0,20747562 0,22583717 ! ear development GO:0043583 72 50 0,000 0,20747562 0,22573034 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,20747562 0,22562361 ! lipid modification GO:0030258 73 50 0,000 0,20747562 0,22551698 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,20747562 0,22541045 ! proton transport GO:0015992 75 50 0,000 0,20747562 0,22530403 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,20747562 0,2251977 ! positive regulation of secretion GO:0051047 71 51 0,000 0,21115819 0,22908671 ! hydrogen transport GO:0006818 77 51 0,000 0,21115819 0,2289787 ! muscle fiber development GO:0048747 74 51 0,000 0,21115819 0,2288708 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,21115819 0,22876299 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,21115819 0,22865529 ! transition metal ion transport GO:0000041 74 52 0,000 0,21482385 0,23251523 ! regulation of cellular component size GO:0032535 74 52 0,000 0,21482385 0,23240586 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,21482385 0,2322966 ! establishment of organelle localization GO:0051656 85 52 0,000 0,21482385 0,23218743 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,21847269 0,23602029 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,21847269 0,23590948 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,21847269 0,23579877 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,21847269 0,23568817 ! kidney development GO:0001822 90 53 0,000 0,21847269 0,23557768 ! cell projection assembly GO:0030031 76 53 0,000 0,21847269 0,23546729 ! amino acid transport GO:0006865 84 54 0,000 0,22210478 0,23926979 ! regulation of mitosis GO:0007088 84 54 0,000 0,22210478 0,23915777 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,22210478 0,23904586 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,22210478 0,23893405 ! DNA catabolic process GO:0006308 67 54 0,000 0,22210478 0,23882235 ! detection of external stimulus GO:0009581 66 54 0,000 0,22210478 0,23871075 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,22210478 0,23859925 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,22210478 0,23848786 ! exocytosis GO:0006887 74 55 0,000 0,2257202 0,24225686 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,2257202 0,24214387 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,2257202 0,24203098 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,22931902 0,24577528 ! carbohydrate transport GO:0008643 74 57 0,000 0,23290132 0,24949839 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,23290132 0,24938223 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,23290132 0,24926619 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,23290132 0,24915025 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,23290132 0,24903442 ! secondary metabolic process GO:0019748 84 57 0,000 0,23290132 0,2489187 ! developmental maturation GO:0021700 75 57 0,000 0,23290132 0,24880308 ! gonad development GO:0008406 79 57 0,000 0,23290132 0,24868758 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,23646717 0,25237796 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,23646717 0,2522609 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,24001666 0,25592875 ! actin filament organization GO:0007015 95 59 0,000 0,24001666 0,25581015 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,24001666 0,25569167 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,24354984 0,25933548 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,24354984 0,25921547 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,24354984 0,25909557 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,24354984 0,25897579 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,24354984 0,25885611 ! regulation of heart contraction GO:0008016 91 60 0,000 0,24354984 0,25873655 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,24354984 0,2586171 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,24354984 0,25849775 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,2470668 0,26210961 ! meiosis GO:0007126 96 61 0,000 0,2470668 0,26198877 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,2470668 0,26186804 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,2470668 0,26174741 ! urogenital system development GO:0001655 101 61 0,000 0,2470668 0,2616269 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,2470668 0,26150651 ! extracellular matrix organization GO:0030198 103 61 0,000 0,2470668 0,26138622 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,2470668 0,26126604 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,2470668 0,26114597 ! amine catabolic process GO:0009310 90 62 0,000 0,25056761 0,26472462 ! neurotransmitter transport GO:0006836 81 62 0,000 0,25056761 0,26460307 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,25056761 0,26448164 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,25056761 0,26436032 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,25056761 0,26423911 ! meiotic cell cycle GO:0051321 97 62 0,000 0,25056761 0,26411801 ! organelle localization GO:0051640 96 62 0,000 0,25056761 0,26399702 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,25405234 0,26754596 ! appendage morphogenesis GO:0035107 93 64 0,000 0,25752107 0,27107481 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,25752107 0,2709508 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,25752107 0,27082691 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,25752107 0,27070313 ! hexose catabolic process GO:0019320 82 64 0,000 0,25752107 0,27057947 ! adaptive immune response GO:0002250 94 64 0,000 0,25752107 0,27045591 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,26097386 0,27395704 ! appendage development GO:0048736 94 65 0,000 0,26097386 0,27383206 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,26097386 0,2737072 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,26097386 0,27358244 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,26097386 0,2734578 ! activation of immune response GO:0002253 83 65 0,000 0,26097386 0,27333328 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,2644108 0,27680693 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,2644108 0,276681 ! antigen processing and presentation GO:0019882 96 66 0,000 0,2644108 0,27655518 ! axon guidance GO:0007411 99 66 0,000 0,2644108 0,27642947 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,2644108 0,27630388 ! regulation of immune effector process GO:0002697 101 66 0,000 0,2644108 0,2761784 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,26783195 0,27962482 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,26783195 0,27949795 ! acute inflammatory response GO:0002526 92 68 0,000 0,27123738 0,28292334 ! learning or memory GO:0007611 123 68 0,000 0,27123738 0,28279509 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,27123738 0,28266696 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,27123738 0,28253894 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,27123738 0,28241103 ! rhythmic process GO:0048511 105 68 0,000 0,27123738 0,28228325 ! inorganic anion transport GO:0015698 93 68 0,000 0,27123738 0,28215557 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,27462717 0,28555266 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,27462717 0,28542363 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,27462717 0,28529471 ! response to metal ion GO:0010038 103 70 0,000 0,27800138 0,28866961 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,27800138 0,28853934 ! humoral immune response GO:0006959 86 70 0,000 0,27800138 0,28840919 ! amine transport GO:0015837 101 70 0,000 0,27800138 0,28827916 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,28136009 0,29163056 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,28136009 0,2914992 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,28136009 0,29136795 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,28136009 0,29123682 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,28136009 0,29110581 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,28470337 0,29443245 ! negative regulation of transport GO:0051051 116 73 0,000 0,28803129 0,29774021 ! regulation of blood pressure GO:0008217 107 73 0,000 0,28803129 0,29760645 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,28803129 0,29747282 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,28803129 0,2973393 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,29134391 0,30062405 ! digestion GO:0007586 97 74 0,000 0,29134391 0,30048924 ! blood coagulation GO:0007596 116 75 0,000 0,29464131 0,30375393 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,29464131 0,30361784 ! response to nutrient GO:0007584 104 75 0,000 0,29464131 0,30348187 ! regulation of ligase activity GO:0051340 114 75 0,000 0,29464131 0,30334603 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,29464131 0,3032103 ! amine biosynthetic process GO:0009309 97 76 0,000 0,29792356 0,30645089 ! tRNA metabolic process GO:0006399 95 76 0,000 0,29792356 0,3063139 ! response to unfolded protein GO:0006986 99 76 0,000 0,29792356 0,30617703 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,30119072 0,30939645 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,30119072 0,30925833 ! sex differentiation GO:0007548 105 77 0,000 0,30119072 0,30912033 ! protein ubiquitination GO:0016567 125 77 0,000 0,30119072 0,30898245 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,30119072 0,3088447 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,30119072 0,30870707 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,30119072 0,30856956 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,30444286 0,3117625 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,30444286 0,31162376 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,30444286 0,31148514 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,30768006 0,31465724 ! cellular respiration GO:0045333 107 79 0,000 0,30768006 0,31451739 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,30768006 0,31437767 ! regulation of lyase activity GO:0051339 133 79 0,000 0,30768006 0,31423807 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,30768006 0,31409859 ! alcohol catabolic process GO:0046164 104 80 0,000 0,31090237 0,31724732 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,31090237 0,31710663 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,31090237 0,31696607 ! forebrain development GO:0030900 131 80 0,000 0,31090237 0,31682563 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,31410987 0,31995248 ! hemostasis GO:0007599 125 81 0,000 0,31410987 0,31981085 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,31410987 0,31966934 ! response to protein stimulus GO:0051789 111 81 0,000 0,31410987 0,31952795 ! vitamin metabolic process GO:0006766 103 81 0,000 0,31410987 0,31938669 ! detection of stimulus GO:0051606 108 82 0,000 0,31730262 0,32249051 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,3204807 0,32557668 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,3204807 0,32543294 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,3204807 0,32528932 ! regulation of defense response GO:0031347 117 84 0,000 0,32364416 0,32835534 ! sterol metabolic process GO:0016125 120 84 0,000 0,32364416 0,32821057 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,32679307 0,33125785 ! rRNA metabolic process GO:0016072 107 85 0,000 0,32679307 0,33111192 GO:0006364|rRNA processing, ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,32992751 0,33414058 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,33304753 0,33715199 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! female pregnancy GO:0007565 130 87 0,000 0,33304753 0,33700366 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,3361532 0,33999664 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,3361532 0,33984719 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,3361532 0,33969787 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,33924459 0,3426713 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,33924459 0,34252087 ! regulation of T cell activation GO:0050863 128 89 0,000 0,33924459 0,34237058 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,34232175 0,34532458 ! hormone metabolic process GO:0042445 121 90 0,000 0,34232175 0,34517319 ! ATP metabolic process GO:0046034 137 91 0,000 0,34538477 0,3481091 ! response to virus GO:0009615 122 91 0,000 0,34538477 0,34795662 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,34843369 0,35087456 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,34843369 0,350721 ! positive regulation of immune response GO:0050778 121 92 0,000 0,34843369 0,35056758 ! DNA recombination GO:0006310 146 92 0,000 0,34843369 0,3504143 ! sulfur metabolic process GO:0006790 118 92 0,000 0,34843369 0,35026114 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,35146859 0,35315761 ! electron transport chain GO:0022900 123 94 0,000 0,35448953 0,35603751 ! response to oxidative stress GO:0006979 141 94 0,000 0,35448953 0,35588211 ! angiogenesis GO:0001525 149 95 0,000 0,35749656 0,35874437 ! carboxylic acid transport GO:0046942 147 95 0,000 0,35749656 0,35858792 GO:0015849|organic acid transport, ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,36048976 0,36143263 ! protein maturation GO:0051604 129 96 0,000 0,36048976 0,36127514 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,36346919 0,36410241 ! extracellular structure organization GO:0043062 156 99 0,000 0,36938698 0,36986942 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,37232546 0,3726495 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,37232546 0,37248741 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,37232546 0,37232546