pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1134-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 5,202E-07 1,251E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 5,992E-07 7,209E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 9,382E-07 7,525E-04 ! interphase GO:0051325 213 98 5,000 1,127E-06 6,779E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 2,149E-06 1,034E-03 ! ER overload response GO:0006983 12 8 2,000 2,149E-06 8,616E-04 ! dendrite development GO:0016358 59 28 3,000 2,48E-06 8,523E-04 ! protein oligomerization GO:0051259 139 78 4,000 7,346E-06 2,209E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 2,106E-05 5,63E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 2,551E-05 6,138E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 2,849E-05 6,232E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! response to UV GO:0009411 104 53 3,000 3,321E-05 6,659E-03 ! positive regulation of translation GO:0045727 30 19 2,000 3,617E-05 6,695E-03 ! G1 phase GO:0051318 40 19 2,000 3,617E-05 6,217E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 4,133E-05 6,629E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 4,245E-05 6,383E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 4,433E-05 6,274E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 5,706E-05 7,627E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 5,706E-05 7,226E-03 ! protein tetramerization GO:0051262 52 24 2,000 7,462E-05 8,977E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 8,38E-05 9,601E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 8,38E-05 9,164E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 8,459E-05 8,849E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 8,459E-05 8,48E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 8,459E-05 8,141E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 8,88E-05 8,218E-03 ! cell cycle checkpoint GO:0000075 137 69 3,000 9,402E-05 8,378E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 9,402E-05 8,079E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 9,538E-05 7,913E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 1,07E-04 8,585E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 1,07E-04 8,308E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 1,07E-04 8,048E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 1,11E-04 8,094E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,151E-04 8,142E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,151E-04 7,909E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 1,151E-04 7,69E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,151E-04 7,482E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 1,151E-04 7,285E-03 ! glial cell migration GO:0008347 11 5 1,000 1,151E-04 7,098E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 1,151E-04 6,921E-03 GO:0051930|regulation of sensory perception of pain, ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,196E-04 7,018E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,331E-04 7,622E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 1,331E-04 7,445E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 1,475E-04 8,064E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 1,592E-04 8,511E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 1,722E-04 9,007E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! male sex determination GO:0030238 15 6 1,000 1,722E-04 8,815E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 1,722E-04 8,632E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,722E-04 8,455E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 1,722E-04 8,286E-03 ! DNA damage checkpoint GO:0000077 71 33 2,000 1,967E-04 9,28E-03 ! negative regulation of growth GO:0045926 155 84 3,000 2,018E-04 9,336E-03 ! regulation of microtubule-based process GO:0032886 78 35 2,000 2,348E-04 0,01065901 ! regulation of helicase activity GO:0051095 15 7 1,000 2,405E-04 0,01071745 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 2,405E-04 0,01052259 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,405E-04 0,01033468 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,405E-04 0,01015337 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 2,405E-04 9,978E-03 ! vesicle fusion GO:0006906 17 7 1,000 2,405E-04 9,809E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,405E-04 9,646E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,405E-04 9,488E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,405E-04 9,335E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,405E-04 9,186E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,405E-04 9,043E-03 ! axonal fasciculation GO:0007413 18 7 1,000 2,405E-04 8,904E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 2,405E-04 8,769E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 2,405E-04 8,638E-03 ! DNA integrity checkpoint GO:0031570 75 36 2,000 2,555E-04 9,041E-03 ! negative regulation of cell activation GO:0050866 65 36 2,000 2,555E-04 8,91E-03 ! glycogen metabolic process GO:0005977 61 37 2,000 2,774E-04 9,533E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 2,774E-04 9,399E-03 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 3,004E-04 0,01003815 ! glucan metabolic process GO:0044042 62 38 2,000 3,004E-04 9,901E-03 GO:0006073|cellular glucan metabolic process, ! carbohydrate phosphorylation GO:0046835 11 8 1,000 3,2E-04 0,0104045 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,2E-04 0,01026578 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 3,2E-04 0,0101307 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 3,502E-04 0,01094291 ! cell cycle arrest GO:0007050 213 100 3,000 3,932E-04 0,0121301 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 4,047E-04 0,01232693 ! regulation of developmental growth GO:0048638 15 9 1,000 4,105E-04 0,0123463 ! axon extension GO:0048675 15 9 1,000 4,105E-04 0,01219388 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 4,105E-04 0,01204517 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 4,105E-04 0,01190005 ! regulation of glycolysis GO:0006110 21 9 1,000 4,105E-04 0,01175838 ! microtubule bundle formation GO:0001578 21 9 1,000 4,105E-04 0,01162005 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 1,000 4,105E-04 0,01148493 ! protein heterooligomerization GO:0051291 16 9 1,000 4,105E-04 0,01135292 ! gas homeostasis GO:0033483 16 9 1,000 4,105E-04 0,01122391 ! induction of an organ GO:0001759 14 9 1,000 4,105E-04 0,0110978 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 4,105E-04 0,01097449 ! energy reserve metabolic process GO:0006112 74 43 2,000 4,34E-04 0,01147551 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 4,966E-04 0,01298686 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 5,12E-04 0,01324597 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 5,12E-04 0,01310505 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 5,12E-04 0,0129671 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 5,12E-04 0,01283203 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 5,12E-04 0,01269974 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 5,12E-04 0,01257015 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 5,12E-04 0,01244318 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 5,299E-04 0,01274984 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 5,299E-04 0,01262361 ! response to insulin stimulus GO:0032868 95 46 2,000 5,299E-04 0,01249985 ! positive regulation of protein transport GO:0051222 72 46 2,000 5,299E-04 0,01237849 ! protein homooligomerization GO:0051260 76 47 2,000 5,646E-04 0,01306292 ! positive regulation of cell cycle GO:0045787 89 48 2,000 6,008E-04 0,01376693 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 6,244E-04 0,01417231 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 6,244E-04 0,01403986 ! regulation of intracellular pH GO:0051453 19 11 1,000 6,244E-04 0,01390986 ! nucleosome positioning GO:0016584 15 11 1,000 6,244E-04 0,01378225 ! developmental induction GO:0031128 19 11 1,000 6,244E-04 0,01365696 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 6,244E-04 0,01353392 ! negative regulation of immune system process GO:0002683 95 50 2,000 6,775E-04 0,01455348 ! regulation of cell shape GO:0008360 125 51 2,000 7,18E-04 0,01528831 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 7,476E-04 0,01577804 ! virus-host interaction GO:0019048 29 12 1,000 7,476E-04 0,01564084 ! regulation of B cell proliferation GO:0030888 20 12 1,000 7,476E-04 0,01550601 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 7,476E-04 0,01537348 ! histone acetylation GO:0016573 26 12 1,000 7,476E-04 0,01524319 ! gland morphogenesis GO:0022612 29 12 1,000 7,476E-04 0,0151151 ! peptidyl-lysine modification GO:0018205 21 12 1,000 7,476E-04 0,01498914 ! cell recognition GO:0008037 85 54 2,000 8,489E-04 0,01687964 ! lipid localization GO:0010876 28 13 1,000 8,815E-04 0,01738518 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 8,815E-04 0,01724384 ! response to X-ray GO:0010165 25 13 1,000 8,815E-04 0,01710477 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 8,815E-04 0,01696794 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 8,815E-04 0,01683327 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 8,815E-04 0,01670073 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 8,815E-04 0,01657025 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 8,956E-04 0,01670487 ! positive regulation of cell migration GO:0030335 126 57 2,000 9,94E-04 0,01839641 ! regulation of intracellular transport GO:0032386 101 57 2,000 9,94E-04 0,01825597 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,026E-03 0,01870435 ! stem cell development GO:0048864 43 14 1,000 1,026E-03 0,01856371 GO:0019827|stem cell maintenance, ! response to gamma radiation GO:0010332 28 14 1,000 1,026E-03 0,01842518 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,026E-03 0,01828869 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 1,154E-03 0,02041361 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 1,154E-03 0,0202646 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,181E-03 0,02059758 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,181E-03 0,02044939 ! regulation of vasodilation GO:0042312 26 15 1,000 1,181E-03 0,02030333 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 1,211E-03 0,020657 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 1,329E-03 0,02252056 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,347E-03 0,02266639 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,347E-03 0,02250898 ! startle response GO:0001964 28 16 1,000 1,347E-03 0,02235375 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 1,347E-03 0,02220064 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 1,347E-03 0,02204961 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,347E-03 0,02190063 ! neuron recognition GO:0008038 35 16 1,000 1,347E-03 0,02175365 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,347E-03 0,02160862 ! positive regulation of cell motion GO:0051272 146 64 2,000 1,391E-03 0,02216497 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 1,523E-03 0,0241137 ! inositol metabolic process GO:0006020 28 17 1,000 1,523E-03 0,02395609 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,523E-03 0,02380053 ! lung development GO:0030324 144 67 2,000 1,588E-03 0,02464406 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 1,71E-03 0,02637345 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,71E-03 0,02620546 ! respiratory tube development GO:0030323 150 70 2,000 1,801E-03 0,02742156 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 1,907E-03 0,02885566 ! regulation of caspase activity GO:0043281 122 72 2,000 1,952E-03 0,02935738 ! respiratory system development GO:0060541 153 72 2,000 1,952E-03 0,02917503 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 2,112E-03 0,03136 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,114E-03 0,03120542 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 2,114E-03 0,03101515 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,114E-03 0,03082718 ! cellular response to starvation GO:0009267 33 20 1,000 2,114E-03 0,03064147 ! stem cell differentiation GO:0048863 53 20 1,000 2,114E-03 0,03045799 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 2,114E-03 0,03027669 ! sensory perception of pain GO:0019233 30 20 1,000 2,114E-03 0,03009754 ! peptidyl-serine modification GO:0018209 43 20 1,000 2,114E-03 0,02992049 ! binding of sperm to zona pellucida GO:0007339 20 20 1,000 2,114E-03 0,02974552 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 2,114E-03 0,02957258 ! inactivation of MAPK activity GO:0000188 39 21 1,000 2,331E-03 0,03242423 ! cell aging GO:0007569 44 21 1,000 2,331E-03 0,03223788 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 2,331E-03 0,03205367 ! regulation of vasoconstriction GO:0019229 39 21 1,000 2,331E-03 0,03187154 ! sperm-egg recognition GO:0035036 21 21 1,000 2,331E-03 0,03169148 ! microtubule-based transport GO:0010970 54 22 1,000 2,559E-03 0,03458765 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 2,559E-03 0,03439442 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,559E-03 0,03420334 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 2,559E-03 0,03401438 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,559E-03 0,03382748 ! response to hypoxia GO:0001666 171 81 2,000 2,732E-03 0,03591329 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,796E-03 0,03656492 ! protein amino acid O-linked glycosylation GO:0006493 42 23 1,000 2,796E-03 0,03636728 ! sex determination GO:0007530 47 23 1,000 2,796E-03 0,03617175 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,796E-03 0,03597832 ! cell-cell recognition GO:0009988 25 23 1,000 2,796E-03 0,03578695 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 2,828E-03 0,0360048 ! response to oxygen levels GO:0070482 176 83 2,000 2,927E-03 0,03706689 ! vesicle docking GO:0048278 47 24 1,000 3,044E-03 0,03834165 ! membrane depolarization GO:0051899 39 24 1,000 3,044E-03 0,03814196 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 3,044E-03 0,03794433 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 3,044E-03 0,03774874 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 3,044E-03 0,03755516 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 3,044E-03 0,03736355 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 3,044E-03 0,03717389 ! vasculogenesis GO:0001570 46 25 1,000 3,301E-03 0,04011295 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 3,301E-03 0,03991137 ! sperm motility GO:0030317 31 25 1,000 3,301E-03 0,03971182 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 3,301E-03 0,03951425 ! negative regulation of DNA replication GO:0008156 42 25 1,000 3,301E-03 0,03931863 ! response to starvation GO:0042594 42 25 1,000 3,301E-03 0,03912494 ! negative regulation of cell development GO:0010721 73 25 1,000 3,301E-03 0,03893315 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 3,301E-03 0,03874324 ! somitogenesis GO:0001756 43 25 1,000 3,301E-03 0,03855516 ! regulation of blood coagulation GO:0030193 40 25 1,000 3,301E-03 0,03836891 ! cellular response to nutrient levels GO:0031669 41 25 1,000 3,301E-03 0,03818444 ! regulation of protein transport GO:0051223 154 87 2,000 3,344E-03 0,03849216 GO:0070201|regulation of establishment of protein localization, ! regulation of cell morphogenesis GO:0022604 215 89 2,000 3,565E-03 0,04084276 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 3,568E-03 0,04068769 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 3,568E-03 0,04049577 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 3,568E-03 0,04030565 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 3,568E-03 0,0401173 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 3,568E-03 0,03993071 ! protein amino acid acylation GO:0043543 55 27 1,000 3,845E-03 0,04283013 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,845E-03 0,04263276 ! base-excision repair GO:0006284 41 27 1,000 3,845E-03 0,04243719 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 4,034E-03 0,04431325 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 4,132E-03 0,04518552 ! regulation of pH GO:0006885 43 29 1,000 4,428E-03 0,04820569 ! respiratory gaseous exchange GO:0007585 57 29 1,000 4,428E-03 0,04798855 ! cell fate determination GO:0001709 60 29 1,000 4,428E-03 0,04777335 ! regulation of coagulation GO:0050818 46 29 1,000 4,428E-03 0,04756008 ! regulation of protein localization GO:0032880 176 97 2,000 4,538E-03 0,04852608 ! membrane docking GO:0022406 61 30 1,000 4,734E-03 0,05039414 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 4,734E-03 0,05017214 ! regulation of B cell activation GO:0050864 50 30 1,000 4,734E-03 0,04995208 ! skeletal muscle tissue development GO:0007519 186 99 2,000 4,804E-03 0,05047223 GO:0060538|skeletal muscle organ development, ! cholesterol homeostasis GO:0042632 53 31 1,000 5,049E-03 0,05281524 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 43 31 1,000 5,049E-03 0,0525866 ! erythrocyte differentiation GO:0030218 55 31 1,000 5,049E-03 0,05235993 ! mesoderm formation GO:0001707 69 31 1,000 5,049E-03 0,05213521 ! cholesterol transport GO:0030301 56 32 1,000 5,373E-03 0,05525035 ! response to ionizing radiation GO:0010212 65 32 1,000 5,373E-03 0,05501525 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 5,373E-03 0,05478213 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 5,373E-03 0,05455098 ! positive regulation of catabolic process GO:0009896 64 32 1,000 5,373E-03 0,05432178 ! post-embryonic development GO:0009791 69 33 1,000 5,707E-03 0,0574567 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 5,707E-03 0,0572173 ! formation of primary germ layer GO:0001704 72 33 1,000 5,707E-03 0,05697988 ! cell fate specification GO:0001708 52 33 1,000 5,707E-03 0,05674443 ! sterol transport GO:0015918 57 33 1,000 5,707E-03 0,05651091 ! adult locomotory behavior GO:0008344 59 33 1,000 5,707E-03 0,05627931 ! mesoderm morphogenesis GO:0048332 76 34 1,000 6,051E-03 0,05942061 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 6,051E-03 0,05917906 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 6,403E-03 0,06237294 ! neutral lipid metabolic process GO:0006638 50 35 1,000 6,403E-03 0,06212144 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 6,403E-03 0,06187195 ! calcium-mediated signaling GO:0019722 62 35 1,000 6,403E-03 0,06162447 ! neural tube formation GO:0001841 67 35 1,000 6,403E-03 0,06137895 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 6,765E-03 0,06458808 ! tissue remodeling GO:0048771 76 37 1,000 7,136E-03 0,06785823 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 7,136E-03 0,06759107 ! glycerol ether metabolic process GO:0006662 53 37 1,000 7,136E-03 0,06732601 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 7,515E-03 0,07063189 ! carbohydrate homeostasis GO:0033500 53 38 1,000 7,515E-03 0,07035706 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 1,000 7,515E-03 0,07008436 ! erythrocyte homeostasis GO:0034101 64 38 1,000 7,515E-03 0,06981376 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 7,515E-03 0,06954525 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 7,515E-03 0,06927879 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 7,904E-03 0,07258373 ! organic ether metabolic process GO:0018904 55 39 1,000 7,904E-03 0,07230775 ! segmentation GO:0035282 67 39 1,000 7,904E-03 0,07203386 ! gliogenesis GO:0042063 88 41 1,000 8,708E-03 0,07906149 ! T cell differentiation GO:0030217 81 41 1,000 8,708E-03 0,07876426 ! polyol metabolic process GO:0019751 66 41 1,000 8,708E-03 0,07846927 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 9,123E-03 0,08190361 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 9,123E-03 0,08159914 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 9,123E-03 0,08129692 ! neuron migration GO:0001764 79 42 1,000 9,123E-03 0,08099693 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 9,123E-03 0,08069914 ! striated muscle cell differentiation GO:0051146 82 43 1,000 9,547E-03 0,08413907 ! neural tube development GO:0021915 77 43 1,000 9,547E-03 0,083832 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 9,547E-03 0,08352715 ! double-strand break repair GO:0006302 81 44 1,000 9,979E-03 0,08699472 ! B cell differentiation GO:0030183 107 44 1,000 9,979E-03 0,08668066 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,01042051 0,09018611 ! cell growth GO:0016049 84 45 1,000 0,01042051 0,08986286 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,01087008 0,09340504 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,0113281 0,09699432 ! mitochondrial transport GO:0006839 82 48 1,000 0,0117945 0,10062969 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,0117945 0,10027411 ! activation of caspase activity GO:0006919 84 48 1,000 0,0117945 0,09992103 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,0117945 0,09957043 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,01226923 0,10321597 ! neuromuscular process GO:0050905 99 50 1,000 0,01275222 0,10690537 ! histone modification GO:0016570 91 50 1,000 0,01275222 0,10653417 ! positive regulation of binding GO:0051099 78 51 1,000 0,01324341 0,11025484 ! vesicle organization GO:0016050 107 51 1,000 0,01324341 0,10987465 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,01324341 0,10949707 ! positive regulation of growth GO:0045927 90 52 1,000 0,01374274 0,11323644 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,01374274 0,11284997 ! membrane fusion GO:0006944 110 52 1,000 0,01374274 0,11246613 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01374274 0,11208489 ! regulation of translational initiation GO:0006446 82 53 1,000 0,01425016 0,11583066 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01425016 0,11544066 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,01425016 0,11505328 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01476559 0,11881608 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,01476559 0,11842003 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01528898 0,12221028 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01528898 0,12180561 ! aging GO:0007568 103 55 1,000 0,01528898 0,12140361 ! gastrulation GO:0007369 112 55 1,000 0,01528898 0,12100426 ! heart morphogenesis GO:0003007 97 55 1,000 0,01528898 0,12060752 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01582028 0,12439082 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,01582028 0,12398564 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01635942 0,12779467 ! adult behavior GO:0030534 99 58 1,000 0,01690634 0,13163965 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01690634 0,131215 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01698453 0,13139802 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01698453 0,13097688 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01698453 0,13055842 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01698453 0,13014263 ! neuron fate determination GO:0048664 7 5 0,000 0,01698453 0,12972948 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01698453 0,12931894 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01698453 0,128911 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01698453 0,12850561 ! polyol transport GO:0015791 12 5 0,000 0,01698453 0,12810278 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01698453 0,12770245 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01698453 0,12730463 ! response to superoxide GO:0000303 10 5 0,000 0,01698453 0,12690927 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01698453 0,12651636 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01698453 0,12612588 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01698453 0,1257378 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01698453 0,1253521 ! female meiosis GO:0007143 7 5 0,000 0,01698453 0,12496876 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01698453 0,12458776 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01698453 0,12420907 ! cobalt ion transport GO:0006824 11 5 0,000 0,01698453 0,12383268 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01698453 0,12345857 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01698453 0,1230867 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01698453 0,12271707 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01698453 0,12234966 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01698453 0,12198443 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01698453 0,12162139 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01698453 0,12126049 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01698453 0,12090173 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01698453 0,12054509 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01698453 0,12019055 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01698453 0,11983808 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01698453 0,11948768 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01698453 0,11913932 ! negative chemotaxis GO:0050919 14 5 0,000 0,01698453 0,11879298 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01698453 0,11844865 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01698453 0,11810632 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01698453 0,11776595 ! behavioral response to pain GO:0048266 9 5 0,000 0,01698453 0,11742754 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01698453 0,11709108 ! Notch receptor processing GO:0007220 8 5 0,000 0,01698453 0,11675653 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01698453 0,11642389 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01698453 0,11609314 ! micturition GO:0060073 9 5 0,000 0,01698453 0,11576426 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01698453 0,11543725 ! copulation GO:0007620 9 5 0,000 0,01698453 0,11511207 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01698453 0,11478872 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01698453 0,11446719 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01698453 0,11414745 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01698453 0,11382949 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01698453 0,11351329 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01698453 0,11319885 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01698453 0,11288615 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01698453 0,11257517 ! grooming behavior GO:0007625 6 5 0,000 0,01698453 0,11226589 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01698453 0,11195832 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01698453 0,11165242 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01698453 0,11134819 ! response to protozoan GO:0001562 10 5 0,000 0,01698453 0,11104561 ! lymph vessel development GO:0001945 10 5 0,000 0,01698453 0,11074468 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01698453 0,11044537 ! endochondral ossification GO:0001958 16 5 0,000 0,01698453 0,11014767 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01698453 0,10985157 ! parathyroid gland development GO:0060017 13 5 0,000 0,01698453 0,10955707 ! anagen GO:0042640 6 5 0,000 0,01698453 0,10926413 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01698453 0,10897276 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01698453 0,10868294 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01698453 0,10839466 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01698453 0,1081079 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01698453 0,10782265 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01698453 0,10753891 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01698453 0,10725665 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01698453 0,10697588 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01698453 0,10669657 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01698453 0,10641871 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01698453 0,1061423 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01698453 0,10586732 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01698453 0,10559376 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01698453 0,10532161 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01698453 0,10505086 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01698453 0,1047815 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01698453 0,10451352 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01698453 0,1042469 ! histidine catabolic process GO:0006548 6 5 0,000 0,01698453 0,10398164 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01698453 0,10371773 ! microvillus organization GO:0032528 7 5 0,000 0,01698453 0,10345515 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01698453 0,1031939 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01698453 0,10293397 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01698453 0,10267534 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01698453 0,10241801 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01698453 0,10216196 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01698453 0,1019072 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01698453 0,1016537 ! polyol catabolic process GO:0046174 7 5 0,000 0,01698453 0,10140145 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01698453 0,10115046 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01698453 0,1009007 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01698453 0,10065218 ! muscle cell migration GO:0014812 8 5 0,000 0,01698453 0,10040488 ! mitochondrial fission GO:0000266 8 5 0,000 0,01698453 0,10015879 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01698453 0,0999139 ! mRNA transcription GO:0009299 9 5 0,000 0,01698453 0,09967021 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01698453 0,0994277 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01698453 0,09918637 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01698453 0,09894621 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01698453 0,09870721 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01698453 0,09846936 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01698453 0,09823266 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01698453 0,09799709 ! response to food GO:0032094 6 5 0,000 0,01698453 0,09776264 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01698453 0,09752932 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01698453 0,09729711 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01698453 0,097066 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01698453 0,09683598 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01698453 0,09660706 ! forebrain neuron development GO:0021884 13 5 0,000 0,01698453 0,09637921 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01698453 0,09615244 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01698453 0,09592673 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01698453 0,09570207 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01698453 0,09547847 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01698453 0,09525591 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01698453 0,09503438 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01698453 0,09481389 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01698453 0,09459441 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01698453 0,09437595 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01698453 0,09415849 ! basic amino acid transport GO:0015802 11 5 0,000 0,01698453 0,09394204 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01698453 0,09372657 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01698453 0,09351209 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01698453 0,0932986 ! depyrimidination GO:0045008 10 5 0,000 0,01698453 0,09308607 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01698453 0,09287451 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01698453 0,09266391 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01698453 0,09245427 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01698453 0,09224557 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01698453 0,09203781 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01698453 0,09183098 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01698453 0,09162508 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01698453 0,0914201 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01698453 0,09121604 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01698453 0,09101289 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01698453 0,09081063 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01698453 0,09060928 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01698453 0,09040882 ! response to arsenic GO:0046685 10 5 0,000 0,01698453 0,09020924 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01698453 0,09001054 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01698453 0,08981272 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01698453 0,08961576 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01698453 0,08941966 ! response to cadmium ion GO:0046686 7 5 0,000 0,01698453 0,08922442 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01698453 0,08903003 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01698453 0,08883649 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01698453 0,08864379 ! decidualization GO:0046697 11 5 0,000 0,01698453 0,08845192 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01698453 0,08826088 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01698453 0,08807066 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01698453 0,08788126 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01698453 0,08769267 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01698453 0,08750489 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01698453 0,08731792 ! neural tube patterning GO:0021532 7 5 0,000 0,01698453 0,08713174 ! embryonic cleavage GO:0040016 6 5 0,000 0,01698453 0,08694635 ! peroxisome fission GO:0016559 5 5 0,000 0,01698453 0,08676175 ! histone demethylation GO:0016577 10 5 0,000 0,01698453 0,08657794 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01698453 0,0863949 ! mitotic recombination GO:0006312 9 5 0,000 0,01698453 0,08621263 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01698453 0,08603113 ! metaphase plate congression GO:0051310 7 5 0,000 0,01698453 0,08585039 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01698453 0,08567041 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01698453 0,08549118 ! enteric nervous system development GO:0048484 8 5 0,000 0,01698453 0,0853127 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01698453 0,08513497 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01698453 0,08495797 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01698453 0,08478171 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01698453 0,08460618 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01698453 0,08443138 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01698453 0,08425729 ! plasminogen activation GO:0031639 5 5 0,000 0,01698453 0,08408392 ! B cell homeostasis GO:0001782 13 5 0,000 0,01698453 0,08391126 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01698453 0,08373931 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01698453 0,08356807 ! metaphase GO:0051323 8 5 0,000 0,01698453 0,08339752 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01698453 0,08322767 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01698453 0,08305851 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01698453 0,08289003 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01698453 0,08272224 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01698453 0,08255512 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01698453 0,08238868 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01698453 0,08222291 ! response to redox state GO:0051775 5 5 0,000 0,01698453 0,0820578 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01698453 0,08189336 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01698453 0,08172957 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01698453 0,08156644 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01698453 0,08140396 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01698453 0,08124212 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01698453 0,08108092 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01698453 0,08092037 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01698453 0,08076045 ! striatum development GO:0021756 9 5 0,000 0,01698453 0,08060115 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01698453 0,08044249 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01698453 0,08028445 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01698453 0,08012703 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01698453 0,07997023 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01698453 0,07981403 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01698453 0,07965845 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01698453 0,07950347 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01698453 0,0793491 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01698453 0,07919532 ! neuroprotection GO:0043526 6 5 0,000 0,01698453 0,07904214 ! neural plate development GO:0001840 8 5 0,000 0,01698453 0,07888955 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01698453 0,07873754 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01698453 0,07858613 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01698453 0,07843529 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01698453 0,07828503 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01698453 0,07813535 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01698453 0,07798623 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01698453 0,07783769 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01698453 0,07768971 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01698453 0,07754229 ! spindle assembly GO:0051225 6 5 0,000 0,01698453 0,07739543 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01698453 0,07724912 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01698453 0,07710337 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01698453 0,07695816 ! drug metabolic process GO:0017144 6 5 0,000 0,01698453 0,07681351 ! stem cell division GO:0017145 11 5 0,000 0,01698453 0,07666939 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01698453 0,07652582 ! organ regeneration GO:0031100 7 5 0,000 0,01698453 0,07638278 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01698453 0,07624027 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01698453 0,0760983 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01698453 0,07595685 ! camera-type eye development GO:0043010 116 60 1,000 0,0180233 0,0804528 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,01859322 0,08284313 ! mesoderm development GO:0007498 119 61 1,000 0,01859322 0,08269 ! viral reproductive process GO:0022415 126 62 1,000 0,0191707 0,08510092 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,01975567 0,08753615 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,020347 0,08999059 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,020347 0,08982547 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,020347 0,08966095 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,020347 0,08949704 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,020347 0,08933372 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,020347 0,089171 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,020347 0,08900887 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,020347 0,08884733 ! sleep GO:0030431 13 6 0,000 0,020347 0,08868638 ! response to oxygen radical GO:0000305 11 6 0,000 0,020347 0,088526 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,020347 0,08836621 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,020347 0,08820699 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,020347 0,08804835 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,020347 0,08789027 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,020347 0,08773276 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,020347 0,08757581 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,020347 0,08741943 ! forebrain regionalization GO:0021871 8 6 0,000 0,020347 0,0872636 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,020347 0,08710833 ! male meiosis GO:0007140 7 6 0,000 0,020347 0,08695361 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,020347 0,08679943 ! response to zinc ion GO:0010043 9 6 0,000 0,020347 0,08664581 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,020347 0,08649272 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,020347 0,08634018 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,020347 0,08618817 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,020347 0,0860367 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,020347 0,08588575 ! malate metabolic process GO:0006108 11 6 0,000 0,020347 0,08573534 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,020347 0,08558545 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,020347 0,08543609 ! protein refolding GO:0042026 15 6 0,000 0,020347 0,08528725 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,020347 0,08513892 ! opsonization GO:0008228 8 6 0,000 0,020347 0,08499111 ! mating behavior GO:0007617 7 6 0,000 0,020347 0,08484381 ! neuron remodeling GO:0016322 15 6 0,000 0,020347 0,08469702 ! erythrocyte maturation GO:0043249 7 6 0,000 0,020347 0,08455074 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,020347 0,08440497 ! equilibrioception GO:0050957 14 6 0,000 0,020347 0,08425969 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,020347 0,08411491 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,020347 0,08397063 ! photoreceptor cell development GO:0042461 10 6 0,000 0,020347 0,08382685 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,020347 0,08368356 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,020347 0,08354075 ! response to interferon-gamma GO:0034341 15 6 0,000 0,020347 0,08339843 ! toxin metabolic process GO:0009404 11 6 0,000 0,020347 0,0832566 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,020347 0,08311525 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,020347 0,08297437 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,020347 0,08283398 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,020347 0,08269405 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,020347 0,0825546 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,020347 0,08241562 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,020347 0,08227711 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,020347 0,08213906 ! thymic T cell selection GO:0045061 12 6 0,000 0,020347 0,08200147 ! protein lipoylation GO:0009249 10 6 0,000 0,020347 0,08186435 ! cysteine metabolic process GO:0006534 10 6 0,000 0,020347 0,08172768 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,020347 0,08159147 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,020347 0,08145571 ! glutamate catabolic process GO:0006538 10 6 0,000 0,020347 0,0813204 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,020347 0,08118554 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,020347 0,08105113 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,020347 0,08091716 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,020347 0,08078363 ! hyperosmotic response GO:0006972 9 6 0,000 0,020347 0,08065054 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,020347 0,08051789 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,020347 0,08038568 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,020347 0,0802539 ! urea metabolic process GO:0019627 7 6 0,000 0,020347 0,08012255 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,020347 0,07999163 ! neutrophil activation GO:0042119 8 6 0,000 0,020347 0,07986114 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,020347 0,07973108 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,020347 0,07960143 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,020347 0,07947221 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,020347 0,0793434 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,020347 0,07921502 ! neuron apoptosis GO:0051402 9 6 0,000 0,020347 0,07908704 ! nucleoside salvage GO:0043174 9 6 0,000 0,020347 0,07895948 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,020347 0,07883234 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,020347 0,07870559 ! T cell mediated immunity GO:0002456 16 6 0,000 0,020347 0,07857926 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,020347 0,07845333 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,020347 0,07832781 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,020347 0,07820268 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,020347 0,07807796 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,020347 0,07795363 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,020347 0,0778297 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,020347 0,07770616 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,020347 0,07758301 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,020347 0,07746025 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,020347 0,07733788 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,020347 0,0772159 ! establishment of spindle localization GO:0051293 12 6 0,000 0,020347 0,0770943 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,020347 0,07697308 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,020347 0,07685224 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,020347 0,07673179 ! neural nucleus development GO:0048857 14 6 0,000 0,020347 0,07661171 ! response to UV-C GO:0010225 11 6 0,000 0,020347 0,076492 ! astrocyte development GO:0014002 15 6 0,000 0,020347 0,07637267 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,020347 0,07625371 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,020347 0,07613512 ! interaction with symbiont GO:0051702 13 6 0,000 0,020347 0,07601689 ! regulation of dendrite development GO:0050773 16 6 0,000 0,020347 0,07589904 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,020347 0,07578155 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,020347 0,07566442 ! response to copper ion GO:0046688 10 6 0,000 0,020347 0,07554765 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,020347 0,07543125 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,020347 0,0753152 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,020347 0,07519951 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,020347 0,07508417 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,020347 0,07496919 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,020347 0,07485456 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,020347 0,07474027 ! hair follicle maturation GO:0048820 7 6 0,000 0,020347 0,07462634 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,020347 0,07451276 ! Schwann cell development GO:0014044 15 6 0,000 0,020347 0,07439951 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,020347 0,07428662 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,020347 0,07417406 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,020347 0,07406185 ! subpallium development GO:0021544 10 6 0,000 0,020347 0,07394997 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,020347 0,07383843 ! histone ubiquitination GO:0016574 8 6 0,000 0,020347 0,07372723 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,020347 0,07361636 ! maintenance of organ identity GO:0048496 9 6 0,000 0,020347 0,07350583 ! G2 phase GO:0051319 16 6 0,000 0,020347 0,07339562 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,020347 0,07328575 ! establishment of planar polarity GO:0001736 7 6 0,000 0,020347 0,0731762 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,020347 0,07306699 ! membrane to membrane docking GO:0022614 14 6 0,000 0,020347 0,07295809 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,020347 0,07284952 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,020347 0,07274128 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,020347 0,07263335 ! receptor internalization GO:0031623 10 6 0,000 0,020347 0,07252575 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,020347 0,07241846 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,020347 0,07231149 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,020347 0,07220484 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,020347 0,0720985 ! protein deubiquitination GO:0016579 14 6 0,000 0,020347 0,07199247 ! protein destabilization GO:0031648 9 6 0,000 0,020347 0,07188675 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,020347 0,07178135 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,020347 0,07167625 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,020347 0,07157146 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,020347 0,07146698 ! progesterone metabolic process GO:0042448 10 6 0,000 0,020347 0,0713628 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,020347 0,07125892 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,020347 0,07115535 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,020347 0,07105208 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,020347 0,0709491 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,020347 0,07084643 ! determination of adult lifespan GO:0008340 15 6 0,000 0,020347 0,07074405 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,020347 0,07064196 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,020347 0,07054017 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,020347 0,07043868 ! catecholamine transport GO:0051937 9 6 0,000 0,020347 0,07033747 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,020347 0,07023656 ! sensory cilium assembly GO:0035058 10 6 0,000 0,020347 0,07013593 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,020347 0,07003559 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,020347 0,06993554 ! maternal placenta development GO:0001893 12 6 0,000 0,020347 0,06983578 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,020347 0,0697363 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,020347 0,0696371 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,020347 0,06953818 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,020347 0,06943955 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,020347 0,06934119 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,020347 0,06924311 ! single fertilization GO:0007338 75 64 1,000 0,02034807 0,06914896 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,02094786 0,07108681 ! activation of MAPK activity GO:0000187 115 67 1,000 0,02216935 0,075126 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,02216935 0,07502033 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,02216935 0,07491497 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,02279094 0,07690745 ! viral reproduction GO:0016032 134 68 1,000 0,02279094 0,07679973 ! regulation of lipase activity GO:0060191 130 68 1,000 0,02279094 0,07669232 ! tRNA transcription GO:0009304 14 7 0,000 0,02369808 0,07963348 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02369808 0,07952241 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02369808 0,07941166 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02369808 0,07930121 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02369808 0,07919107 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02369808 0,07908123 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02369808 0,0789717 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02369808 0,07886248 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02369808 0,07875355 ! prostate gland development GO:0030850 13 7 0,000 0,02369808 0,07864492 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02369808 0,0785366 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02369808 0,07842857 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02369808 0,07832084 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02369808 0,0782134 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02369808 0,07810626 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02369808 0,07799941 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02369808 0,07789285 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02369808 0,07778659 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02369808 0,07768061 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02369808 0,07757492 ! glycolipid transport GO:0046836 10 7 0,000 0,02369808 0,07746952 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02369808 0,07736441 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02369808 0,07725958 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02369808 0,07715503 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02369808 0,07705077 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02369808 0,07694679 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02369808 0,07684309 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02369808 0,07673966 ! mRNA stabilization GO:0048255 18 7 0,000 0,02369808 0,07663652 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02369808 0,07653365 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02369808 0,07643106 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02369808 0,07632874 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02369808 0,0762267 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02369808 0,07612493 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02369808 0,07602343 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02369808 0,0759222 ! lipoprotein transport GO:0042953 14 7 0,000 0,02369808 0,07582124 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02369808 0,07572054 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02369808 0,07562012 ! rhythmic behavior GO:0007622 15 7 0,000 0,02369808 0,07551996 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02369808 0,07542007 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02369808 0,07532044 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02369808 0,07522107 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02369808 0,07512196 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02369808 0,07502312 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02369808 0,07492453 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02369808 0,07482621 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02369808 0,07472814 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02369808 0,07463033 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02369808 0,07453277 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02369808 0,07443547 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02369808 0,07433842 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02369808 0,07424163 ! spinal cord patterning GO:0021511 13 7 0,000 0,02369808 0,07414508 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02369808 0,07404879 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02369808 0,07395275 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02369808 0,07385696 ! adrenal gland development GO:0030325 17 7 0,000 0,02369808 0,07376141 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02369808 0,07366611 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02369808 0,07357106 ! ovulation GO:0030728 9 7 0,000 0,02369808 0,07347625 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02369808 0,07338169 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02369808 0,07328736 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02369808 0,07319329 ! microtubule nucleation GO:0007020 20 7 0,000 0,02369808 0,07309945 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02369808 0,07300585 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02369808 0,07291249 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02369808 0,07281937 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02369808 0,07272649 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02369808 0,07263385 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02369808 0,07254144 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02369808 0,07244926 ! galactose metabolic process GO:0006012 13 7 0,000 0,02369808 0,07235732 ! response to dietary excess GO:0002021 8 7 0,000 0,02369808 0,07226561 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02369808 0,07217414 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02369808 0,07208289 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02369808 0,07199188 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02369808 0,0719011 ! organ growth GO:0035265 15 7 0,000 0,02369808 0,07181054 ! purine salvage GO:0043101 10 7 0,000 0,02369808 0,07172021 ! nucleoside transport GO:0015858 8 7 0,000 0,02369808 0,07163011 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02369808 0,07154024 ! parturition GO:0007567 14 7 0,000 0,02369808 0,07145059 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02369808 0,07136116 ! rRNA modification GO:0000154 14 7 0,000 0,02369808 0,07127196 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02369808 0,07118298 ! spindle checkpoint GO:0031577 15 7 0,000 0,02369808 0,07109423 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02369808 0,07100569 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02369808 0,07091738 ! macrophage differentiation GO:0030225 11 7 0,000 0,02369808 0,07082928 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02369808 0,0707414 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02369808 0,07065374 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02369808 0,0705663 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02369808 0,07047907 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02369808 0,07039206 ! fibrinolysis GO:0042730 10 7 0,000 0,02369808 0,07030526 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02369808 0,07021868 ! eating behavior GO:0042755 7 7 0,000 0,02369808 0,07013231 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02369808 0,07004615 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02369808 0,06996021 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02369808 0,06987447 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02369808 0,06978895 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02369808 0,06970363 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02369808 0,06961852 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02369808 0,06953362 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02369808 0,06944893 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02369808 0,06936444 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02369808 0,06928016 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02369808 0,06919608 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02369808 0,06911221 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02369808 0,06902853 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02369808 0,06894507 ! regulation of meiosis GO:0040020 12 7 0,000 0,02369808 0,0688618 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02369808 0,06877873 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02369808 0,06869587 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02369808 0,0686132 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02369808 0,06853073 ! transcription termination GO:0006353 13 7 0,000 0,02369808 0,06844846 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02369808 0,06836639 ! anaphase GO:0051322 17 7 0,000 0,02369808 0,06828451 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02369808 0,06820283 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02369808 0,06812135 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02369808 0,06804006 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02369808 0,06795896 ! diuresis GO:0030146 12 7 0,000 0,02369808 0,06787806 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02369808 0,06779735 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02369808 0,06771683 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02369808 0,0676365 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02369808 0,06755636 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02369808 0,06747641 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02369808 0,06739665 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02369808 0,06731708 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02369808 0,0672377 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02369808 0,0671585 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02369808 0,06707949 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02369808 0,06700067 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02369808 0,06692203 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02369808 0,06684358 ! lymph node development GO:0048535 10 7 0,000 0,02369808 0,0667653 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02369808 0,06668722 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02369808 0,06660931 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02369808 0,06653159 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02369808 0,06645404 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02369808 0,06637668 ! adult feeding behavior GO:0008343 9 7 0,000 0,02369808 0,0662995 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02369808 0,0662225 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02369808 0,06614567 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02369808 0,06606903 ! muscle adaptation GO:0043500 14 7 0,000 0,02369808 0,06599256 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02369808 0,06591627 ! retina homeostasis GO:0001895 12 7 0,000 0,02369808 0,06584015 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02369808 0,06576421 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02369808 0,06568844 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02369808 0,06561285 ! protein prenylation GO:0018342 18 7 0,000 0,02369808 0,06553744 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02369808 0,06546219 ! B cell activation GO:0042113 160 71 1,000 0,02469844 0,06814731 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,02469844 0,06806924 ! fertilization GO:0009566 90 73 1,000 0,02600516 0,07158858 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,02666887 0,07333178 GO:0090046|regulation of transcription regulator activity, ! eye development GO:0001654 143 74 1,000 0,02666887 0,07324807 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0270378 0,07417668 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0270378 0,07409219 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0270378 0,0740079 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0270378 0,0739238 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0270378 0,07383989 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0270378 0,07375617 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0270378 0,07367265 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0270378 0,07358931 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0270378 0,07350615 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0270378 0,07342319 ! meiotic prophase I GO:0007128 13 8 0,000 0,0270378 0,07334041 ! oligopeptide transport GO:0006857 15 8 0,000 0,0270378 0,07325782 ! UTP metabolic process GO:0046051 8 8 0,000 0,0270378 0,07317542 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0270378 0,0730932 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0270378 0,07301116 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0270378 0,07292931 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0270378 0,07284764 ! succinate metabolic process GO:0006105 14 8 0,000 0,0270378 0,07276616 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0270378 0,07268486 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0270378 0,07260373 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0270378 0,07252279 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0270378 0,07244203 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0270378 0,07236145 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0270378 0,07228105 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0270378 0,07220083 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0270378 0,07212078 ! reflex GO:0060004 16 8 0,000 0,0270378 0,07204092 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0270378 0,07196122 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0270378 0,07188171 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0270378 0,07180237 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0270378 0,0717232 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0270378 0,07164421 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0270378 0,0715654 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0270378 0,07148675 ! pigment granule organization GO:0048753 16 8 0,000 0,0270378 0,07140828 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0270378 0,07132999 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0270378 0,07125186 ! histidine metabolic process GO:0006547 16 8 0,000 0,0270378 0,0711739 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0270378 0,07109612 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0270378 0,0710185 ! glycine catabolic process GO:0006546 13 8 0,000 0,0270378 0,07094105 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0270378 0,07086378 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0270378 0,07078667 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0270378 0,07070972 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0270378 0,07063295 ! melanin metabolic process GO:0006582 15 8 0,000 0,0270378 0,07055634 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0270378 0,0704799 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0270378 0,07040362 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0270378 0,07032751 ! macrophage activation GO:0042116 12 8 0,000 0,0270378 0,07025156 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0270378 0,07017578 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0270378 0,07010016 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0270378 0,0700247 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0270378 0,0699494 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0270378 0,06987427 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0270378 0,0697993 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0270378 0,06972449 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0270378 0,06964984 ! osteoblast development GO:0002076 16 8 0,000 0,0270378 0,06957534 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0270378 0,06950101 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0270378 0,06942684 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0270378 0,06935282 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0270378 0,06927896 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0270378 0,06920526 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0270378 0,06913172 ! response to UV-B GO:0010224 16 8 0,000 0,0270378 0,06905833 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0270378 0,0689851 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0270378 0,06891202 ! intermediate filament organization GO:0045109 12 8 0,000 0,0270378 0,0688391 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0270378 0,06876633 ! cellular extravasation GO:0045123 12 8 0,000 0,0270378 0,06869371 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0270378 0,06862125 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0270378 0,06854894 ! response to antibiotic GO:0046677 11 8 0,000 0,0270378 0,06847679 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0270378 0,06840478 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0270378 0,06833293 ! DNA topological change GO:0006265 12 8 0,000 0,0270378 0,06826122 ! response to tropane GO:0014073 15 8 0,000 0,0270378 0,06818967 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0270378 0,06811827 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,0270378 0,06804701 ! melanosome transport GO:0032402 13 8 0,000 0,0270378 0,06797591 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,0270378 0,06790495 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0270378 0,06783415 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0270378 0,06776349 ! mast cell activation GO:0045576 14 8 0,000 0,0270378 0,06769297 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0270378 0,06762261 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0270378 0,06755238 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0270378 0,06748231 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0270378 0,06741238 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0270378 0,06734259 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0270378 0,06727295 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0270378 0,06720346 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0270378 0,0671341 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0270378 0,06706489 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0270378 0,06699583 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0270378 0,0669269 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0270378 0,06685812 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0270378 0,06678947 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0270378 0,06672097 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0270378 0,06665261 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0270378 0,06658439 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0270378 0,06651631 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0270378 0,06644836 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0270378 0,06638056 ! hormone catabolic process GO:0042447 17 8 0,000 0,0270378 0,06631289 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0270378 0,06624536 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0270378 0,06617797 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0270378 0,06611072 ! ATP catabolic process GO:0006200 11 8 0,000 0,0270378 0,0660436 ! blastocyst growth GO:0001832 19 8 0,000 0,0270378 0,06597662 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0270378 0,06590977 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0270378 0,06584306 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0270378 0,06577649 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0270378 0,06571005 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0270378 0,06564374 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0270378 0,06557757 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0270378 0,06551153 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0270378 0,06544562 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0270378 0,06537985 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0270378 0,0653142 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0270378 0,06524869 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0270378 0,06518331 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0270378 0,06511806 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0270378 0,06505295 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0270378 0,06498796 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0270378 0,0649231 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0270378 0,06485837 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02733941 0,06551657 ! defense response to bacterium GO:0042742 89 76 1,000 0,02801673 0,0670729 ! regulation of catabolic process GO:0009894 161 76 1,000 0,02801673 0,06700622 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02870078 0,06857405 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,02939149 0,07015468 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,02939149 0,07008515 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,03008882 0,07167693 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03036621 0,07226617 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03036621 0,07219476 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03036621 0,0721235 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03036621 0,07205237 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03036621 0,07198138 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03036621 0,07191053 ! phosphate transport GO:0006817 19 9 0,000 0,03036621 0,07183982 ! reproductive behavior GO:0019098 19 9 0,000 0,03036621 0,07176925 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03036621 0,07169882 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03036621 0,07162853 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03036621 0,07155838 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03036621 0,07148836 ! GTP metabolic process GO:0046039 9 9 0,000 0,03036621 0,07141848 ! RNA methylation GO:0001510 15 9 0,000 0,03036621 0,07134873 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03036621 0,07127912 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03036621 0,07120965 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03036621 0,07114031 ! artery development GO:0060840 24 9 0,000 0,03036621 0,07107111 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03036621 0,07100204 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03036621 0,07093311 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03036621 0,07086431 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03036621 0,07079564 ! chemosensory behavior GO:0007635 20 9 0,000 0,03036621 0,07072711 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03036621 0,07065871 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03036621 0,07059044 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03036621 0,0705223 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03036621 0,07045429 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03036621 0,07038642 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03036621 0,07031867 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03036621 0,07025106 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03036621 0,07018357 ! protein targeting to ER GO:0045047 22 9 0,000 0,03036621 0,07011622 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03036621 0,07004899 ! T cell selection GO:0045058 23 9 0,000 0,03036621 0,0699819 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,03036621 0,06991493 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03036621 0,06984809 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03036621 0,06978138 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03036621 0,06971479 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03036621 0,06964833 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03036621 0,069582 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03036621 0,0695158 ! mannose metabolic process GO:0006013 13 9 0,000 0,03036621 0,06944972 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03036621 0,06938376 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03036621 0,06931793 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03036621 0,06925223 ! receptor clustering GO:0043113 18 9 0,000 0,03036621 0,06918665 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03036621 0,06912119 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03036621 0,06905586 ! ruffle organization GO:0031529 15 9 0,000 0,03036621 0,06899065 ! retinol metabolic process GO:0042572 18 9 0,000 0,03036621 0,06892557 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03036621 0,0688606 ! behavioral fear response GO:0001662 22 9 0,000 0,03036621 0,06879576 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03036621 0,06873105 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03036621 0,06866645 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03036621 0,06860197 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03036621 0,06853762 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03036621 0,06847338 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03036621 0,06840927 ! segment specification GO:0007379 13 9 0,000 0,03036621 0,06834528 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03036621 0,0682814 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03036621 0,06821765 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03036621 0,06815401 ! response to amine stimulus GO:0014075 13 9 0,000 0,03036621 0,0680905 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03036621 0,0680271 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03036621 0,06796382 ! erythrocyte development GO:0048821 15 9 0,000 0,03036621 0,06790065 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03036621 0,06783761 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03036621 0,06777468 ! renal water homeostasis GO:0003091 14 9 0,000 0,03036621 0,06771186 ! postreplication repair GO:0006301 22 9 0,000 0,03036621 0,06764917 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03036621 0,06758659 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03036621 0,06752412 ! icosanoid secretion GO:0032309 15 9 0,000 0,03036621 0,06746177 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03036621 0,06739954 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03036621 0,06733742 ! regulation of cell division GO:0051302 15 9 0,000 0,03036621 0,06727542 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03036621 0,06721352 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03036621 0,06715175 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03036621 0,06709008 ! sterol catabolic process GO:0016127 11 9 0,000 0,03036621 0,06702853 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03036621 0,0669671 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03036621 0,06690577 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03036621 0,06684456 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03036621 0,06678346 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03036621 0,06672247 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03036621 0,06666159 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03036621 0,06660082 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03036621 0,06654017 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03036621 0,06647962 ! purine base metabolic process GO:0006144 21 9 0,000 0,03036621 0,06641918 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03036621 0,06635886 ! pigment granule transport GO:0051904 17 9 0,000 0,03036621 0,06629864 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03036621 0,06623853 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,03036621 0,06617853 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03036621 0,06611864 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03036621 0,06605886 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03036621 0,06599919 ! mitochondrion localization GO:0051646 15 9 0,000 0,03036621 0,06593962 ! muscle cell differentiation GO:0042692 159 80 1,000 0,03079271 0,06680547 ! protein import into nucleus GO:0006606 158 80 1,000 0,03079271 0,06674529 ! T cell activation GO:0042110 168 81 1,000 0,03150312 0,06822369 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,03150312 0,06816233 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,03150312 0,06810109 ! nuclear import GO:0051170 161 81 1,000 0,03150312 0,06803996 ! response to drug GO:0042493 143 82 1,000 0,03221999 0,06952583 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03368334 0,07261839 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03368334 0,07255338 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03368334 0,07248849 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03368334 0,07242371 ! synapsis GO:0007129 13 10 0,000 0,03368334 0,07235904 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03368334 0,07229449 ! N-glycan processing GO:0006491 20 10 0,000 0,03368334 0,07223006 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03368334 0,07216574 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03368334 0,07210154 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03368334 0,07203745 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03368334 0,07197347 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03368334 0,07190961 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03368334 0,07184586 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03368334 0,07178222 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03368334 0,0717187 ! androgen metabolic process GO:0008209 17 10 0,000 0,03368334 0,07165528 ! phospholipid efflux GO:0033700 16 10 0,000 0,03368334 0,07159198 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03368334 0,0715288 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03368334 0,07146572 ! lung alveolus development GO:0048286 26 10 0,000 0,03368334 0,07140275 ! pathogenesis GO:0009405 13 10 0,000 0,03368334 0,0713399 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03368334 0,07127716 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03368334 0,07121452 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03368334 0,071152 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03368334 0,07108958 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03368334 0,07102728 ! endoderm development GO:0007492 16 10 0,000 0,03368334 0,07096508 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03368334 0,070903 ! arginine catabolic process GO:0006527 13 10 0,000 0,03368334 0,07084102 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03368334 0,07077915 ! proline metabolic process GO:0006560 13 10 0,000 0,03368334 0,07071739 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03368334 0,07065573 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03368334 0,07059419 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03368334 0,07053275 ! V(D)J recombination GO:0033151 28 10 0,000 0,03368334 0,07047141 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03368334 0,07041019 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03368334 0,07034907 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03368334 0,07028805 ! B cell proliferation GO:0042100 18 10 0,000 0,03368334 0,07022715 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03368334 0,07016634 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03368334 0,07010565 ! multicellular organism growth GO:0035264 18 10 0,000 0,03368334 0,07004505 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03368334 0,06998457 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03368334 0,06992418 ! epithelial cell development GO:0002064 20 10 0,000 0,03368334 0,0698639 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03368334 0,06980373 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03368334 0,06974365 ! macroautophagy GO:0016236 17 10 0,000 0,03368334 0,06968369 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03368334 0,06962382 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03368334 0,06956406 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03368334 0,0695044 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03368334 0,06944484 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03368334 0,06938538 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03368334 0,06932603 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03368334 0,06926678 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03368334 0,06920762 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03368334 0,06914857 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03368334 0,06908962 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03368334 0,06903077 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03368334 0,06897202 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03368334 0,06891337 ! response to dsRNA GO:0043331 20 10 0,000 0,03368334 0,06885482 ! DNA ligation GO:0006266 19 10 0,000 0,03368334 0,06879637 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03368334 0,06873802 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03368334 0,06867977 ! melanosome localization GO:0032400 16 10 0,000 0,03368334 0,06862161 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03368334 0,06856356 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03368334 0,0685056 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03368334 0,06844774 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03368334 0,06838998 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03368334 0,06833232 ! mRNA cleavage GO:0006379 17 10 0,000 0,03368334 0,06827475 ! protein sumoylation GO:0016925 15 10 0,000 0,03368334 0,06821728 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03368334 0,0681599 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03368334 0,06810263 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03368334 0,06804545 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03368334 0,06798836 ! salivary gland development GO:0007431 27 10 0,000 0,03368334 0,06793137 ! prophase GO:0051324 15 10 0,000 0,03368334 0,06787448 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03368334 0,06781768 ! apical protein localization GO:0045176 15 10 0,000 0,03368334 0,06776098 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03368334 0,06770437 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03368334 0,06764785 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03368334 0,06759143 ! midbrain development GO:0030901 13 10 0,000 0,03368334 0,06753511 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03368334 0,06747887 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03368334 0,06742273 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03368334 0,06736669 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03368334 0,06731074 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03368334 0,06725488 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03368334 0,06719911 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03368334 0,06714344 ! detection of calcium ion GO:0005513 23 10 0,000 0,03368334 0,06708785 ! oocyte development GO:0048599 17 10 0,000 0,03368334 0,06703236 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03368334 0,06697696 ! blastocyst formation GO:0001825 17 10 0,000 0,03368334 0,06692166 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03368334 0,06686644 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03368334 0,06681132 ! activation of innate immune response GO:0002218 12 10 0,000 0,03368334 0,06675628 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03368334 0,06670134 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03368334 0,06664649 ! response to nicotine GO:0035094 20 10 0,000 0,03368334 0,06659172 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03368334 0,06653705 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03368334 0,06648247 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03368334 0,06642797 ! nucleosome assembly GO:0006334 122 85 1,000 0,03440886 0,06780321 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,03440886 0,06774772 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 124 86 1,000 0,03515106 0,06915246 ! tube morphogenesis GO:0035239 176 86 1,000 0,03515106 0,06909596 ! mitochondrion organization GO:0007005 148 86 1,000 0,03515106 0,06903956 ! protein localization in nucleus GO:0034504 176 87 1,000 0,03589947 0,07045198 ! regulation of DNA binding GO:0051101 155 88 1,000 0,03665404 0,07187418 ! gland development GO:0048732 206 88 1,000 0,03665404 0,07181565 ! regulation of neurological system process GO:0031644 148 88 1,000 0,03665404 0,07175721 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03698924 0,07235456 ! respiratory burst GO:0045730 17 11 0,000 0,03698924 0,07229579 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03698924 0,0722371 ! neuron fate specification GO:0048665 17 11 0,000 0,03698924 0,07217852 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03698924 0,07212003 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03698924 0,07206163 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03698924 0,07200333 ! thyroid gland development GO:0030878 26 11 0,000 0,03698924 0,07194512 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03698924 0,07188701 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03698924 0,07182899 ! response to pain GO:0048265 24 11 0,000 0,03698924 0,07177106 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03698924 0,07171323 ! T cell proliferation GO:0042098 26 11 0,000 0,03698924 0,07165549 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03698924 0,07159784 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03698924 0,07154028 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03698924 0,07148282 ! bone resorption GO:0045453 16 11 0,000 0,03698924 0,07142545 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03698924 0,07136817 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03698924 0,07131099 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03698924 0,07125389 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03698924 0,07119689 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03698924 0,07113998 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03698924 0,07108316 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03698924 0,07102643 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03698924 0,07096979 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03698924 0,07091324 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03698924 0,07085678 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03698924 0,07080041 ! UV protection GO:0009650 19 11 0,000 0,03698924 0,07074413 ! adult heart development GO:0007512 14 11 0,000 0,03698924 0,07068794 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03698924 0,07063184 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03698924 0,07057582 ! temperature homeostasis GO:0001659 17 11 0,000 0,03698924 0,0705199 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03698924 0,07046406 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03698924 0,07040832 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03698924 0,07035266 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03698924 0,07029709 ! regulation of organ growth GO:0046620 13 11 0,000 0,03698924 0,0702416 ! pigment granule localization GO:0051875 20 11 0,000 0,03698924 0,07018621 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03698924 0,0701309 ! vasoconstriction GO:0042310 18 11 0,000 0,03698924 0,07007568 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03698924 0,07002055 ! embryonic axis specification GO:0000578 18 11 0,000 0,03698924 0,0699655 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03698924 0,06991054 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03698924 0,06985566 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03698924 0,06980087 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03698924 0,06974617 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03698924 0,06969155 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03698924 0,06963702 ! zymogen activation GO:0031638 15 11 0,000 0,03698924 0,06958257 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03698924 0,06952821 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03698924 0,06947394 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03698924 0,06941974 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03698924 0,06936564 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03698924 0,06931161 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03698924 0,06925768 ! acid secretion GO:0046717 18 11 0,000 0,03698924 0,06920382 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03698924 0,06915005 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03698924 0,06909636 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03698924 0,06904276 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03698924 0,06898923 ! oocyte differentiation GO:0009994 18 11 0,000 0,03698924 0,0689358 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03698924 0,06888244 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03698924 0,06882917 ! cholesterol efflux GO:0033344 19 11 0,000 0,03698924 0,06877598 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03698924 0,06872287 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03698924 0,06866984 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03698924 0,0686169 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03698924 0,06856403 ! embryonic gut development GO:0048566 15 11 0,000 0,03698924 0,06851125 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03698924 0,06845855 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03698924 0,06840593 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03698924 0,06835339 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03698924 0,06830093 ! defense response to fungus GO:0050832 13 11 0,000 0,03698924 0,06824855 ! lysogeny GO:0030069 21 11 0,000 0,03698924 0,06819626 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03698924 0,06814404 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03698924 0,0680919 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03698924 0,06803984 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03698924 0,06798786 ! nucleus localization GO:0051647 19 11 0,000 0,03698924 0,06793596 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03698924 0,06788414 ! cellular defense response GO:0006968 114 89 1,000 0,03741471 0,06861264 ! ossification GO:0001503 188 90 1,000 0,03818144 0,06996537 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,03818144 0,06991213 ! bone development GO:0060348 189 91 1,000 0,03895417 0,0712728 ! nucleosome organization GO:0034728 138 92 1,000 0,03973286 0,0726423 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04028394 0,07359389 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04028394 0,07353805 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04028394 0,0734823 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04028394 0,07342663 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04028394 0,07337105 ! cartilage condensation GO:0001502 20 12 0,000 0,04028394 0,07331555 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,04028394 0,07326013 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04028394 0,0732048 ! protein complex disassembly GO:0043241 27 12 0,000 0,04028394 0,07314955 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04028394 0,07309438 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,04028394 0,0730393 ! hippocampus development GO:0021766 26 12 0,000 0,04028394 0,0729843 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04028394 0,07292938 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04028394 0,07287455 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,04028394 0,0728198 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04028394 0,07276513 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04028394 0,07271054 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04028394 0,07265604 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04028394 0,07260161 ! drug transport GO:0015893 16 12 0,000 0,04028394 0,07254727 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04028394 0,07249301 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04028394 0,07243883 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04028394 0,07238473 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04028394 0,07233071 ! focal adhesion formation GO:0048041 35 12 0,000 0,04028394 0,07227677 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04028394 0,07222291 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04028394 0,07216914 ! forebrain cell migration GO:0021885 21 12 0,000 0,04028394 0,07211544 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04028394 0,07206182 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04028394 0,07200828 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04028394 0,07195483 ! entry into host cell GO:0030260 32 12 0,000 0,04028394 0,07190145 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,04028394 0,07184815 ! monoamine transport GO:0015844 18 12 0,000 0,04028394 0,07179493 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04028394 0,07174178 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04028394 0,07168872 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04028394 0,07163574 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04028394 0,07158283 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04028394 0,07153 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04028394 0,07147725 ! protein homotetramerization GO:0051289 21 12 0,000 0,04028394 0,07142458 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04028394 0,07137198 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04028394 0,07131946 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04028394 0,07126702 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04028394 0,07121466 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04028394 0,07116237 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04028394 0,07111016 ! cranial nerve development GO:0021545 20 12 0,000 0,04028394 0,07105803 ! fucose catabolic process GO:0019317 22 12 0,000 0,04028394 0,07100597 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04028394 0,07095399 ! histone methylation GO:0016571 26 12 0,000 0,04028394 0,07090209 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04028394 0,07085026 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04028394 0,0707985 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04028394 0,07074683 ! T cell homeostasis GO:0043029 25 12 0,000 0,04028394 0,07069522 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04028394 0,0706437 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04028394 0,07059224 ! spleen development GO:0048536 22 12 0,000 0,04028394 0,07054087 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04028394 0,07048956 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04028394 0,07043834 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04028394 0,07038718 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04028394 0,0703361 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04028394 0,0702851 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04028394 0,07023417 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04028394 0,07018331 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04028394 0,07013253 ! response to cold GO:0009409 17 12 0,000 0,04028394 0,07008182 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04028394 0,07003118 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04028394 0,06998061 ! regulation of membrane potential GO:0042391 164 93 1,000 0,04051746 0,07033551 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,04051746 0,0702848 ! transcription initiation GO:0006352 153 94 1,000 0,04130793 0,07160437 ! leukocyte differentiation GO:0002521 202 96 1,000 0,04290624 0,07432139 ! mRNA transport GO:0051028 169 96 1,000 0,04290624 0,07426792 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04356747 0,07535825 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04356747 0,07530412 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04356747 0,07525006 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04356747 0,07519608 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04356747 0,07514217 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04356747 0,07508835 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04356747 0,0750346 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04356747 0,07498092 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04356747 0,07492733 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04356747 0,07487381 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04356747 0,07482036 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04356747 0,074767 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04356747 0,07471371 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04356747 0,07466049 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04356747 0,07460735 ! methionine metabolic process GO:0006555 27 13 0,000 0,04356747 0,07455429 ! plasma membrane organization GO:0007009 24 13 0,000 0,04356747 0,0745013 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04356747 0,07444839 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04356747 0,07439555 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04356747 0,07434279 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04356747 0,0742901 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04356747 0,07423749 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04356747 0,07418495 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,04356747 0,07413248 ! exocrine system development GO:0035272 32 13 0,000 0,04356747 0,07408009 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04356747 0,07402778 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04356747 0,07397553 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04356747 0,07392336 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04356747 0,07387127 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04356747 0,07381925 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04356747 0,0737673 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04356747 0,07371542 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04356747 0,07366362 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04356747 0,07361189 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04356747 0,07356023 ! ribosome assembly GO:0042255 17 13 0,000 0,04356747 0,07350865 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04356747 0,07345713 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04356747 0,07340569 ! chromatin silencing GO:0006342 26 13 0,000 0,04356747 0,07335433 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04356747 0,07330303 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04356747 0,0732518 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04356747 0,07320065 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04356747 0,07314957 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04356747 0,07309856 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,04356747 0,07304762 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04356747 0,07299675 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04356747 0,07294595 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04356747 0,07289522 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04356747 0,07284457 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04356747 0,07279398 ! embryonic placenta development GO:0001892 23 13 0,000 0,04356747 0,07274346 ! insulin secretion GO:0030073 23 13 0,000 0,04356747 0,07269302 ! actin filament polymerization GO:0030041 24 13 0,000 0,04356747 0,07264264 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04356747 0,07259233 ! acrosome reaction GO:0007340 18 13 0,000 0,04356747 0,0725421 ! rRNA transcription GO:0009303 25 14 0,000 0,04683988 0,07793689 ! lactation GO:0007595 26 14 0,000 0,04683988 0,07788303 ! reproductive cellular process GO:0048610 20 14 0,000 0,04683988 0,07782924 ! tRNA modification GO:0006400 20 14 0,000 0,04683988 0,07777553 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04683988 0,07772189 ! regulation of S phase GO:0033261 23 14 0,000 0,04683988 0,07766833 ! water transport GO:0006833 21 14 0,000 0,04683988 0,07761484 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04683988 0,07756142 ! non-recombinational repair GO:0000726 25 14 0,000 0,04683988 0,07750808 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04683988 0,07745481 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04683988 0,07740161 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04683988 0,07734849 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04683988 0,07729543 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04683988 0,07724246 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04683988 0,07718955 ! palate development GO:0060021 31 14 0,000 0,04683988 0,07713672 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04683988 0,07708396 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04683988 0,07703127 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04683988 0,07697865 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04683988 0,0769261 ! arginine metabolic process GO:0006525 17 14 0,000 0,04683988 0,07687363 ! regulation of heart rate GO:0002027 24 14 0,000 0,04683988 0,07682123 ! organic alcohol transport GO:0015850 29 14 0,000 0,04683988 0,0767689 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04683988 0,07671664 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04683988 0,07666445 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04683988 0,07661233 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04683988 0,07656029 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04683988 0,07650831 ! L-amino acid transport GO:0015807 30 14 0,000 0,04683988 0,07645641 ! bone mineralization GO:0030282 17 14 0,000 0,04683988 0,07640457 ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04683988 0,07635281 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04683988 0,07630111 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04683988 0,07624949 ! cerebellum development GO:0021549 21 14 0,000 0,04683988 0,07619793 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04683988 0,07614645 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04683988 0,07609503 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04683988 0,07604369 ! cofactor transport GO:0051181 26 14 0,000 0,04683988 0,07599241 ! NADP metabolic process GO:0006739 24 14 0,000 0,04683988 0,0759412 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04683988 0,07589006 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04683988 0,07583899 ! intestinal absorption GO:0050892 25 14 0,000 0,04683988 0,07578799 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04683988 0,07573706 ! oxygen transport GO:0015671 21 14 0,000 0,04683988 0,07568619 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04683988 0,0756354 ! male genitalia development GO:0030539 24 14 0,000 0,04683988 0,07558467 ! regulation of RNA stability GO:0043487 32 14 0,000 0,04683988 0,07553401 ! regulation of axon extension GO:0030516 37 14 0,000 0,04683988 0,07548342 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04683988 0,07543289 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0501012 0,08063109 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0501012 0,08057719 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0501012 0,08052336 ! superoxide anion generation GO:0042554 20 15 0,000 0,0501012 0,08046961 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0501012 0,08041593 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0501012 0,08036232 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0501012 0,08030878 ! copper ion transport GO:0006825 20 15 0,000 0,0501012 0,08025531 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0501012 0,08020191 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0501012 0,08014859 ! sulfate transport GO:0008272 23 15 0,000 0,0501012 0,08009533 ! response to cAMP GO:0051591 22 15 0,000 0,0501012 0,08004215 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0501012 0,07998904 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0501012 0,07993599 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0501012 0,07988302 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0501012 0,07983012 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0501012 0,07977728 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0501012 0,07972452 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0501012 0,07967183 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0501012 0,07961921 ! pituitary gland development GO:0021983 29 15 0,000 0,0501012 0,07956665 ! vesicle coating GO:0006901 33 15 0,000 0,0501012 0,07951417 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0501012 0,07946175 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0501012 0,0794094 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0501012 0,07935713 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0501012 0,07930492 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0501012 0,07925278 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0501012 0,07920071 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0501012 0,0791487 ! histone deacetylation GO:0016575 20 15 0,000 0,0501012 0,07909677 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0501012 0,0790449 ! tissue regeneration GO:0042246 26 15 0,000 0,0501012 0,0789931 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0501012 0,07894137 ! water homeostasis GO:0030104 27 15 0,000 0,0501012 0,07888971 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0501012 0,07883811 ! muscle maintenance GO:0046716 26 15 0,000 0,0501012 0,07878659 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0501012 0,07873513 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0501012 0,07868373 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0501012 0,0786324 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0501012 0,07858115 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0501012 0,07852995 ! cell killing GO:0001906 29 15 0,000 0,0501012 0,07847883 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0501012 0,07842777 ! detection of bacterium GO:0016045 18 15 0,000 0,0501012 0,07837677 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0501012 0,07832585 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0501012 0,07827498 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0501012 0,07822419 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0501012 0,07817346 ! peptide hormone processing GO:0016486 23 15 0,000 0,0501012 0,0781228 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,05335146 0,08313706 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05335146 0,08308325 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05335146 0,08302951 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05335146 0,08297584 ! bone remodeling GO:0046849 27 16 0,000 0,05335146 0,08292224 ! filopodium assembly GO:0046847 32 16 0,000 0,05335146 0,0828687 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,05335146 0,08281524 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05335146 0,08276185 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,05335146 0,08270852 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05335146 0,08265526 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,05335146 0,08260207 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05335146 0,08254895 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05335146 0,0824959 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,05335146 0,08244292 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05335146 0,08239 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05335146 0,08233715 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05335146 0,08228437 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05335146 0,08223166 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05335146 0,08217902 ! response to osmotic stress GO:0006970 25 16 0,000 0,05335146 0,08212644 ! lysosomal transport GO:0007041 26 16 0,000 0,05335146 0,08207393 ! fructose metabolic process GO:0006000 25 16 0,000 0,05335146 0,08202148 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05335146 0,08196911 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05335146 0,0819168 ! intermediate filament-based process GO:0045103 32 16 0,000 0,05335146 0,08186456 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,05335146 0,08181238 ! negative regulation of immune response GO:0050777 35 16 0,000 0,05335146 0,08176027 ! axon cargo transport GO:0008088 43 16 0,000 0,05335146 0,08170823 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05335146 0,08165625 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05335146 0,08160434 ! DNA replication initiation GO:0006270 27 16 0,000 0,05335146 0,08155249 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05335146 0,08150071 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05335146 0,081449 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05335146 0,08139735 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05335146 0,08134577 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,05335146 0,08129425 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05335146 0,0812428 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05335146 0,08119141 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05335146 0,08114009 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05335146 0,08108883 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05335146 0,08103764 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05335146 0,08098651 ! defense response to virus GO:0051607 37 16 0,000 0,05335146 0,08093545 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05659072 0,08579538 ! metencephalon development GO:0022037 30 17 0,000 0,05659072 0,08574135 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05659072 0,08568739 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05659072 0,0856335 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05659072 0,08557968 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05659072 0,08552592 ! signal complex assembly GO:0007172 41 17 0,000 0,05659072 0,08547223 ! endothelial cell migration GO:0043542 28 17 0,000 0,05659072 0,08541861 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05659072 0,08536506 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05659072 0,08531157 ! glial cell development GO:0021782 27 17 0,000 0,05659072 0,08525815 ! limbic system development GO:0021761 36 17 0,000 0,05659072 0,0852048 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05659072 0,08515151 ! adult walking behavior GO:0007628 33 17 0,000 0,05659072 0,08509829 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05659072 0,08504514 ! heart looping GO:0001947 30 17 0,000 0,05659072 0,08499205 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05659072 0,08493903 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05659072 0,08488608 ! myoblast differentiation GO:0045445 45 17 0,000 0,05659072 0,08483319 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05659072 0,08478037 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,05659072 0,08472761 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05659072 0,08467492 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05659072 0,08462229 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05659072 0,08456973 ! glycine metabolic process GO:0006544 28 17 0,000 0,05659072 0,08451724 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05659072 0,08446481 ! NAD metabolic process GO:0019674 29 17 0,000 0,05659072 0,08441244 ! membrane budding GO:0006900 37 17 0,000 0,05659072 0,08436014 ! DNA integration GO:0015074 29 17 0,000 0,05659072 0,08430791 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05659072 0,08425574 ! regulation of protein binding GO:0043393 33 17 0,000 0,05659072 0,08420363 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05659072 0,08415159 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05659072 0,08409961 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05659072 0,0840477 ! genitalia development GO:0048806 30 17 0,000 0,05659072 0,08399585 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05659072 0,08394406 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05659072 0,08389234 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05659072 0,08384068 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05659072 0,08378909 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05659072 0,08373756 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05659072 0,08368609 ! steroid catabolic process GO:0006706 31 17 0,000 0,05659072 0,08363469 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05659072 0,08358334 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05659072 0,08353207 ! gas transport GO:0015669 25 17 0,000 0,05659072 0,08348085 ! organic cation transport GO:0015695 31 17 0,000 0,05659072 0,0834297 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05659072 0,08337861 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05659072 0,08332758 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05659072 0,08327662 ! microspike assembly GO:0030035 36 17 0,000 0,05659072 0,08322571 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05659072 0,08317487 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,059819 0,087866 ! neuron maturation GO:0042551 42 18 0,000 0,059819 0,08781239 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,059819 0,08775884 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,059819 0,08770537 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,059819 0,08765195 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,059819 0,0875986 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,059819 0,08754532 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,059819 0,0874921 ! memory GO:0007613 31 18 0,000 0,059819 0,08743895 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,059819 0,08738586 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,059819 0,08733283 ! patterning of blood vessels GO:0001569 39 18 0,000 0,059819 0,08727987 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,059819 0,08722697 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,059819 0,08717414 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,059819 0,08712137 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,059819 0,08706867 ! glutamine metabolic process GO:0006541 29 18 0,000 0,059819 0,08701602 ! response to retinoic acid GO:0032526 26 18 0,000 0,059819 0,08696345 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,059819 0,08691093 ! response to fungus GO:0009620 21 18 0,000 0,059819 0,08685848 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,059819 0,08680609 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,059819 0,08675377 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,059819 0,08670151 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,059819 0,08664931 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,059819 0,08659717 ! vitamin transport GO:0051180 27 18 0,000 0,059819 0,0865451 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,059819 0,08649309 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,059819 0,08644114 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,059819 0,08638926 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,059819 0,08633744 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,059819 0,08628567 ! nerve development GO:0021675 28 18 0,000 0,059819 0,08623398 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,059819 0,08618234 ! protein secretion GO:0009306 39 19 0,000 0,06303633 0,09076327 ! negative regulation of defense response GO:0031348 25 19 0,000 0,06303633 0,09070898 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,06303633 0,09065476 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,06303633 0,09060061 ! skin development GO:0043588 36 19 0,000 0,06303633 0,09054652 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,06303633 0,09049249 ! lipid phosphorylation GO:0046834 35 19 0,000 0,06303633 0,09043853 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06303633 0,09038464 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,06303633 0,0903308 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,06303633 0,09027703 ! bile acid metabolic process GO:0008206 29 19 0,000 0,06303633 0,09022333 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,06303633 0,09016969 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,06303633 0,09011611 ! cerebral cortex development GO:0021987 36 19 0,000 0,06303633 0,0900626 ! pigmentation during development GO:0048066 41 19 0,000 0,06303633 0,09000915 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,06303633 0,08995576 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,06303633 0,08990244 ! heme metabolic process GO:0042168 36 19 0,000 0,06303633 0,08984918 ! actin filament bundle formation GO:0051017 42 19 0,000 0,06303633 0,08979599 ! neuromuscular junction development GO:0007528 34 19 0,000 0,06303633 0,08974285 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,06303633 0,08968978 ! plasma membrane fusion GO:0045026 28 19 0,000 0,06303633 0,08963677 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,06303633 0,08958383 ! peptide cross-linking GO:0018149 37 19 0,000 0,06303633 0,08953094 ! protein export from nucleus GO:0006611 36 19 0,000 0,06303633 0,08947812 ! heart process GO:0003015 30 19 0,000 0,06303633 0,08942536 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,06303633 0,08937267 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,06303633 0,08932003 ! visual learning GO:0008542 36 19 0,000 0,06303633 0,08926746 ! cellular pigmentation GO:0033059 36 19 0,000 0,06303633 0,08921495 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,06303633 0,0891625 ! cell-cell junction organization GO:0045216 35 19 0,000 0,06303633 0,08911012 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,06303633 0,08905779 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,06303633 0,08900553 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,06303633 0,08895332 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,06303633 0,08890118 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,06303633 0,0888491 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,06303633 0,08879708 ! cilium assembly GO:0042384 37 19 0,000 0,06303633 0,08874513 ! peptide hormone secretion GO:0030072 31 19 0,000 0,06303633 0,08869323 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06624277 0,09315026 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,06624277 0,09309585 ! positive regulation of ossification GO:0045778 47 20 0,000 0,06624277 0,09304151 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06624277 0,09298722 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06624277 0,092933 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06624277 0,09287885 ! response to vitamin GO:0033273 31 20 0,000 0,06624277 0,09282475 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06624277 0,09277072 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,06624277 0,09271675 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06624277 0,09266285 ! response to alkaloid GO:0043279 38 20 0,000 0,06624277 0,09260901 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06624277 0,09255523 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,06624277 0,09250151 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06624277 0,09244785 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06624277 0,09239426 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,06624277 0,09234073 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06624277 0,09228726 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06624277 0,09223385 ! body fluid secretion GO:0007589 31 20 0,000 0,06624277 0,09218051 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,06624277 0,09212723 ! peptide secretion GO:0002790 35 20 0,000 0,06624277 0,092074 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06624277 0,09202084 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06624277 0,09196774 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,06624277 0,09191471 ! diencephalon development GO:0021536 34 20 0,000 0,06624277 0,09186173 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06624277 0,09180881 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,06624277 0,09175596 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06624277 0,09170316 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06624277 0,09165043 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06624277 0,09159776 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06624277 0,09154515 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,06624277 0,09149259 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06624277 0,0914401 ! regulation of glucose import GO:0046324 29 20 0,000 0,06624277 0,09138767 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06624277 0,0913353 ! actin filament-based movement GO:0030048 43 20 0,000 0,06624277 0,09128299 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,06624277 0,09123074 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,06624277 0,09117855 ! negative regulation of translation GO:0017148 29 20 0,000 0,06624277 0,09112641 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,06624277 0,09107434 ! regulation of cell killing GO:0031341 42 21 0,000 0,06943834 0,09541327 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06943834 0,09535881 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06943834 0,09530441 ! hormone secretion GO:0046879 38 21 0,000 0,06943834 0,09525008 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06943834 0,0951958 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06943834 0,09514159 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06943834 0,09508744 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06943834 0,09503335 ! axis specification GO:0009798 38 21 0,000 0,06943834 0,09497933 ! ovarian follicle development GO:0001541 35 21 0,000 0,06943834 0,09492536 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06943834 0,09487146 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06943834 0,09481761 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06943834 0,09476383 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06943834 0,09471011 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06943834 0,09465645 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06943834 0,09460285 ! cytolysis GO:0019835 24 21 0,000 0,06943834 0,09454931 ! vasodilation GO:0042311 39 21 0,000 0,06943834 0,09449583 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06943834 0,09444242 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06943834 0,09438906 ! oogenesis GO:0048477 36 21 0,000 0,06943834 0,09433576 ! DNA modification GO:0006304 34 21 0,000 0,06943834 0,09428253 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,06943834 0,09422935 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,06943834 0,09417623 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06943834 0,09412317 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06943834 0,09407018 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,06943834 0,09401724 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,06943834 0,09396436 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06943834 0,09391154 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06943834 0,09385878 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06943834 0,09380608 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06943834 0,09375344 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06943834 0,09370086 ! collagen catabolic process GO:0030574 28 21 0,000 0,06943834 0,09364834 ! gut development GO:0048565 39 21 0,000 0,06943834 0,09359587 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,07262307 0,09783377 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,07262307 0,09777902 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,07262307 0,09772434 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,07262307 0,09766971 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,07262307 0,09761515 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,07262307 0,09756064 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,07262307 0,0975062 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,07262307 0,09745182 ! regeneration GO:0031099 41 22 0,000 0,07262307 0,0973975 ! keratinization GO:0031424 28 22 0,000 0,07262307 0,09734324 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,07262307 0,09728904 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,07262307 0,0972349 ! sensory perception of taste GO:0050909 28 22 0,000 0,07262307 0,09718082 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,07262307 0,0971268 ! vacuolar transport GO:0007034 36 22 0,000 0,07262307 0,09707284 ! lysosome organization GO:0007040 41 22 0,000 0,07262307 0,09701894 ! central nervous system neuron development GO:0021954 46 22 0,000 0,07262307 0,0969651 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,07262307 0,09691132 ! fucose metabolic process GO:0006004 39 22 0,000 0,07262307 0,0968576 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,07262307 0,09680394 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,07262307 0,09675034 ! ureteric bud development GO:0001657 43 22 0,000 0,07262307 0,0966968 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,07262307 0,09664331 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,07262307 0,09658989 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,07262307 0,09653653 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,07262307 0,09648322 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,07262307 0,09642997 ! sarcomere organization GO:0045214 30 22 0,000 0,07262307 0,09637679 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,07262307 0,09632366 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,07262307 0,09627059 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,07262307 0,09621757 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,07262307 0,09616462 ! protein stabilization GO:0050821 39 22 0,000 0,07262307 0,09611172 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,07579702 0,10025708 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,07579702 0,10020199 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,07579702 0,10014696 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07579702 0,100092 ! gluconeogenesis GO:0006094 33 23 0,000 0,07579702 0,10003709 ! viral genome replication GO:0019079 41 23 0,000 0,07579702 0,09998225 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07579702 0,09992746 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07579702 0,09987274 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07579702 0,09981807 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,07579702 0,09976347 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07579702 0,09970892 ! visual behavior GO:0007632 42 23 0,000 0,07579702 0,09965444 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,07579702 0,09960001 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,07579702 0,09954564 ! response to ethanol GO:0045471 46 23 0,000 0,07579702 0,09949134 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07579702 0,09943709 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,07579702 0,0993829 ! peroxisome organization GO:0007031 37 23 0,000 0,07579702 0,09932877 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07579702 0,0992747 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07579702 0,09922069 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07579702 0,09916673 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,07579702 0,09911284 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07579702 0,099059 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,07579702 0,09900522 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07579702 0,0989515 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07579702 0,09889784 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07579702 0,09884424 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07579702 0,09879069 ! fatty acid transport GO:0015908 44 23 0,000 0,07579702 0,09873721 ! platelet activation GO:0030168 37 23 0,000 0,07579702 0,09868378 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07579702 0,09863041 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07579702 0,09857709 ! hormone transport GO:0009914 40 23 0,000 0,07579702 0,09852384 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07579702 0,09847064 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07579702 0,0984175 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,07579702 0,09836441 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07579702 0,09831139 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07579702 0,09825842 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,0789602 0,10230385 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,0789602 0,10224879 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,0789602 0,10219378 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,0789602 0,10213884 ! spinal cord development GO:0021510 47 24 0,000 0,0789602 0,10208396 ! vacuole organization GO:0007033 43 24 0,000 0,0789602 0,10202913 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,0789602 0,10197437 ! digestive system process GO:0022600 39 24 0,000 0,0789602 0,10191966 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,0789602 0,10186501 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,0789602 0,10181042 ! regulation of behavior GO:0050795 43 24 0,000 0,0789602 0,10175589 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,0789602 0,10170142 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,0789602 0,101647 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,0789602 0,10159264 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,0789602 0,10153835 ! pallium development GO:0021543 49 24 0,000 0,0789602 0,10148411 ! pentose metabolic process GO:0019321 35 24 0,000 0,0789602 0,10142992 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,0789602 0,1013758 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,0789602 0,10132173 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,0789602 0,10126772 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,0789602 0,10121377 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,0789602 0,10115987 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,0789602 0,10110604 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,0789602 0,10105226 ! regulation of amine transport GO:0051952 40 24 0,000 0,0789602 0,10099854 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,08211267 0,10497507 ! myelination GO:0042552 45 25 0,000 0,08211267 0,10491932 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,08211267 0,10486363 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,08211267 0,104808 ! phototransduction GO:0007602 33 25 0,000 0,08211267 0,10475242 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,08211267 0,10469691 GO:0006479|protein amino acid methylation, ! receptor metabolic process GO:0043112 46 25 0,000 0,08211267 0,10464146 ! chromosome condensation GO:0030261 45 25 0,000 0,08211267 0,10458606 ! osteoblast differentiation GO:0001649 60 25 0,000 0,08211267 0,10453073 ! neural crest cell development GO:0014032 54 25 0,000 0,08211267 0,10447545 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,08211267 0,10442023 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,08211267 0,10436507 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,08211267 0,10430996 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,08211267 0,10425492 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,08211267 0,10419993 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,08211267 0,104145 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,08211267 0,10409013 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,08211267 0,10403532 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,08211267 0,10398056 ! telomere organization GO:0032200 43 25 0,000 0,08211267 0,10392587 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,08211267 0,10387123 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,08211267 0,10381664 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,08525444 0,10773224 ! embryonic pattern specification GO:0009880 44 26 0,000 0,08525444 0,10767569 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,08525444 0,1076192 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,08525444 0,10756276 ! initiation of viral infection GO:0019059 57 26 0,000 0,08525444 0,10750639 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,08525444 0,10745007 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,08525444 0,10739382 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,08525444 0,10733762 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,08525444 0,10728148 ! molting cycle process GO:0022404 50 26 0,000 0,08525444 0,1072254 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,08525444 0,10716938 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,08525444 0,10711342 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,08525444 0,10705751 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,08525444 0,10700167 GO:0051297|centrosome organization, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,08525444 0,10694588 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,08525444 0,10689015 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,08525444 0,10683447 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,08525444 0,10677886 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,08525444 0,1067233 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,08525444 0,10666781 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,08525444 0,10661237 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,08525444 0,10655698 ! blastocyst development GO:0001824 49 26 0,000 0,08525444 0,10650166 ! leukocyte proliferation GO:0070661 52 26 0,000 0,08525444 0,10644639 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,08525444 0,10639118 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,08525444 0,10633602 ! neuron fate commitment GO:0048663 48 27 0,000 0,08838557 0,11018429 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,08838557 0,11012723 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,08838557 0,11007023 ! iron ion transport GO:0006826 59 27 0,000 0,08838557 0,11001329 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,08838557 0,10995641 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,08838557 0,10989958 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,08838557 0,10984281 ! fat cell differentiation GO:0045444 50 27 0,000 0,08838557 0,10978611 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,08838557 0,10972946 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,08838557 0,10967287 ! autophagy GO:0006914 41 27 0,000 0,08838557 0,10961633 ! male gonad development GO:0008584 44 27 0,000 0,08838557 0,10955986 ! response to toxin GO:0009636 47 27 0,000 0,08838557 0,10950344 ! primary neural tube formation GO:0014020 51 27 0,000 0,08838557 0,10944709 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,08838557 0,10939079 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,08838557 0,10933454 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,08838557 0,10927836 ! glutathione metabolic process GO:0006749 39 27 0,000 0,08838557 0,10922223 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,08838557 0,10916616 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,08838557 0,10911015 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,08838557 0,1090542 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,09150609 0,11284656 ! circadian rhythm GO:0007623 50 28 0,000 0,09150609 0,11278875 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,09150609 0,112731 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,09150609 0,11267331 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,09150609 0,11261568 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,09150609 0,1125581 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,09150609 0,11250059 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,09150609 0,11244313 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,09150609 0,11238573 ! synaptogenesis GO:0007416 42 28 0,000 0,09150609 0,11232839 ! lipid oxidation GO:0034440 43 28 0,000 0,09150609 0,11227111 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,09150609 0,11221389 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,09150609 0,11215672 ! translational initiation GO:0006413 65 29 0,000 0,09461602 0,11590945 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,09461602 0,11585046 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,09461602 0,11579153 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,09461602 0,11573267 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,09461602 0,11567386 ! catechol metabolic process GO:0009712 54 29 0,000 0,09461602 0,11561511 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,09461602 0,11555642 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,09461602 0,11549779 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,09461602 0,11543923 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,09461602 0,11538072 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,09461602 0,11532227 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,09461602 0,11526387 ! detection of light stimulus GO:0009583 38 29 0,000 0,09461602 0,11520554 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,09461602 0,11514727 ! tissue homeostasis GO:0001894 48 29 0,000 0,09461602 0,11508906 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,09771542 0,11879904 ! zinc ion transport GO:0006829 45 30 0,000 0,09771542 0,11873904 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,09771542 0,1186791 ! cell junction assembly GO:0034329 78 30 0,000 0,09771542 0,11861922 ! regulation of innate immune response GO:0045088 51 30 0,000 0,09771542 0,1185594 ! acute-phase response GO:0006953 49 30 0,000 0,09771542 0,11849964 ! myofibril assembly GO:0030239 47 30 0,000 0,09771542 0,11843995 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,09771542 0,11838031 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,09771542 0,11832073 ! phospholipid transport GO:0015914 51 30 0,000 0,09771542 0,11826121 ! ensheathment of neurons GO:0007272 57 30 0,000 0,09771542 0,11820176 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,09771542 0,11814236 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,09771542 0,11808302 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,09771542 0,11802374 ! eye morphogenesis GO:0048592 60 30 0,000 0,09771542 0,11796452 ! response to heat GO:0009408 50 30 0,000 0,09771542 0,11790536 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,1008043 0,12157151 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,1008043 0,1215106 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,1008043 0,12144975 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,1008043 0,12138897 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,1008043 0,12132824 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,1008043 0,12126758 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,1008043 0,12120697 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,1008043 0,12114643 ! ovulation cycle process GO:0022602 49 31 0,000 0,1008043 0,12108595 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,1008043 0,12102553 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,1008043 0,12096516 ! peptide transport GO:0015833 55 31 0,000 0,1008043 0,12090486 ! iron ion homeostasis GO:0055072 54 31 0,000 0,1008043 0,12084462 ! natural killer cell activation GO:0030101 45 31 0,000 0,1008043 0,12078444 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,1008043 0,12072432 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,1008043 0,12066426 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,1008043 0,12060425 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,1008043 0,12054431 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,1008043 0,12048443 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,10388272 0,12410219 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,10388272 0,1240406 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,10388272 0,12397908 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,10388272 0,12391761 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,10388272 0,1238562 ! spliceosome assembly GO:0000245 67 32 0,000 0,10388272 0,12379486 ! spindle organization GO:0007051 46 32 0,000 0,10388272 0,12373357 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,10388272 0,12367235 ! metanephros development GO:0001656 74 32 0,000 0,10388272 0,12361119 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,10388272 0,12355008 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,10388272 0,12348904 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,10388272 0,12342806 ! muscle cell development GO:0055001 49 32 0,000 0,10388272 0,12336714 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,10388272 0,12330627 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,10388272 0,12324547 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,10388272 0,12318473 ! ovulation cycle GO:0042698 51 32 0,000 0,10388272 0,12312405 ! peripheral nervous system development GO:0007422 64 32 0,000 0,10388272 0,12306343 ! BMP signaling pathway GO:0030509 64 32 0,000 0,10388272 0,12300286 ! hindbrain development GO:0030902 61 32 0,000 0,10388272 0,12294236 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,10388272 0,12288192 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,10388272 0,12282153 ! gene silencing GO:0016458 65 32 0,000 0,10388272 0,12276121 ! protein targeting to membrane GO:0006612 68 33 0,000 0,10695069 0,12632468 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,10695069 0,12626269 ! ceramide metabolic process GO:0006672 64 33 0,000 0,10695069 0,12620077 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,10695069 0,12613891 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,10695069 0,1260771 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,10695069 0,12601536 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,10695069 0,12595368 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,11000827 0,12949114 ! glial cell differentiation GO:0010001 63 34 0,000 0,11000827 0,12942782 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,11000827 0,12936456 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,11000827 0,12930136 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,11000827 0,12923823 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,11000827 0,12917516 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,11000827 0,12911214 ! mismatch repair GO:0006298 46 34 0,000 0,11000827 0,12904919 ! spermatid development GO:0007286 63 34 0,000 0,11000827 0,1289863 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,11000827 0,12892347 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,11000827 0,12886071 ! placenta development GO:0001890 53 34 0,000 0,11000827 0,128798 ! regulation of muscle development GO:0048634 70 35 0,000 0,11305548 0,1323013 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,11305548 0,13223698 ! negative regulation of secretion GO:0051048 63 35 0,000 0,11305548 0,13217273 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,11305548 0,13210854 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,11305548 0,13204441 ! odontogenesis GO:0042476 66 35 0,000 0,11305548 0,13198034 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,11305548 0,13191633 ! female gonad development GO:0008585 58 35 0,000 0,11305548 0,13185239 ! telencephalon development GO:0021537 68 35 0,000 0,11305548 0,13178851 ! cytokine production GO:0001816 59 35 0,000 0,11305548 0,13172469 ! vesicle localization GO:0051648 64 35 0,000 0,11305548 0,13166093 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,11609235 0,13513217 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,11609235 0,13506683 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,11609235 0,13500155 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,11609235 0,13493633 ! cell junction organization GO:0034330 86 36 0,000 0,11609235 0,13487117 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,11609235 0,13480608 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,11609235 0,13474105 ! positive regulation of cell development GO:0010720 80 36 0,000 0,11609235 0,13467608 ! regulation of proteolysis GO:0030162 72 36 0,000 0,11609235 0,13461118 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,11609235 0,13454634 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,11609235 0,13448156 ! aerobic respiration GO:0009060 55 36 0,000 0,11609235 0,13441684 ! embryonic organ development GO:0048568 57 36 0,000 0,11609235 0,13435219 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,11609235 0,13428759 ! RNA export from nucleus GO:0006405 56 37 0,000 0,11911893 0,13772232 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,11911893 0,13765617 ! meiosis I GO:0007127 65 37 0,000 0,11911893 0,13759008 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,11911893 0,13752406 ! sister chromatid segregation GO:0000819 58 37 0,000 0,11911893 0,1374581 ! actomyosin structure organization GO:0031032 62 37 0,000 0,11911893 0,13739221 ! organic anion transport GO:0015711 68 37 0,000 0,11911893 0,13732637 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,11911893 0,13726061 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,11911893 0,1371949 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,11911893 0,13712926 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,11911893 0,13706367 ! pigment metabolic process GO:0042440 80 37 0,000 0,11911893 0,13699816 ! spermatid differentiation GO:0048515 66 37 0,000 0,11911893 0,1369327 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,12213524 0,14033305 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,12213524 0,14026606 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,12213524 0,14019914 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,12213524 0,14013228 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,12213524 0,14006549 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,12213524 0,13999876 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,12213524 0,13993209 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,12213524 0,13986549 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,12213524 0,13979895 ! mRNA catabolic process GO:0006402 71 39 0,000 0,12514133 0,14317168 ! learning GO:0007612 77 39 0,000 0,12514133 0,14310363 ! ear morphogenesis GO:0042471 60 39 0,000 0,12514133 0,14303565 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,12514133 0,14296773 ! ion transmembrane transport GO:0034220 66 39 0,000 0,12514133 0,14289988 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,12514133 0,14283209 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,12514133 0,14276436 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,12514133 0,1426967 ! RNA modification GO:0009451 57 39 0,000 0,12514133 0,1426291 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,12514133 0,14256157 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,12813722 0,14590542 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,12813722 0,1458364 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,12813722 0,14576745 ! feeding behavior GO:0007631 59 40 0,000 0,12813722 0,14569856 ! negative regulation of binding GO:0051100 72 40 0,000 0,12813722 0,14562974 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,12813722 0,14556098 ! mesenchymal cell development GO:0014031 87 40 0,000 0,12813722 0,14549229 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,12813722 0,14542366 ! maintenance of protein location GO:0045185 91 40 0,000 0,12813722 0,1453551 ! cytokinesis GO:0000910 72 40 0,000 0,12813722 0,1452866 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,13112295 0,1486019 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,13112295 0,14853193 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,13112295 0,14846204 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,13112295 0,14839221 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,13112295 0,14832244 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,13112295 0,14825274 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,13112295 0,1481831 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,13112295 0,14811353 ! female gamete generation GO:0007292 61 41 0,000 0,13112295 0,14804403 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,13112295 0,14797459 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,13409856 0,15126167 ! regulation of tube size GO:0035150 71 42 0,000 0,13409856 0,15119079 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,13409856 0,15111997 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,13409856 0,15104922 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,13409856 0,15097854 ! regulation of protein secretion GO:0050708 71 42 0,000 0,13409856 0,15090792 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,13706408 0,15417306 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,13706408 0,15410101 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,13706408 0,15402904 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,13706408 0,15395713 ! glucose transport GO:0015758 65 43 0,000 0,13706408 0,15388528 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,13706408 0,15381351 ! striated muscle contraction GO:0006941 77 43 0,000 0,13706408 0,1537418 ! phagocytosis GO:0006909 90 43 0,000 0,13706408 0,15367016 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,13706408 0,15359859 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,14001953 0,15683752 ! hexose transport GO:0008645 67 44 0,000 0,14001953 0,15676454 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,14001953 0,15669162 ! male sex differentiation GO:0046661 76 44 0,000 0,14001953 0,15661878 ! biopolymer methylation GO:0043414 84 44 0,000 0,14001953 0,156546 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,14001953 0,15647329 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,14001953 0,15640065 ! developmental growth GO:0048589 82 44 0,000 0,14001953 0,15632807 ! maintenance of location in cell GO:0051651 97 44 0,000 0,14001953 0,15625556 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,14296496 0,15946857 ! glycolysis GO:0006096 65 45 0,000 0,14296496 0,15939467 ! leukocyte migration GO:0050900 68 45 0,000 0,14296496 0,15932084 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,14296496 0,15924709 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,14296496 0,15917339 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,14296496 0,15909977 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,14296496 0,15902622 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,14296496 0,15895273 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,14296496 0,15887931 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,14296496 0,15880596 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,14590041 0,16199187 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,14590041 0,16191715 ! pigmentation GO:0043473 100 46 0,000 0,14590041 0,1618425 ! positive regulation of defense response GO:0031349 76 47 0,000 0,14882589 0,16501156 ! response to calcium ion GO:0051592 81 47 0,000 0,14882589 0,16493556 ! endosome transport GO:0016197 108 47 0,000 0,14882589 0,16485962 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,14882589 0,16478375 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,14882589 0,16470795 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,14882589 0,16463223 ! JNK cascade GO:0007254 91 47 0,000 0,14882589 0,16455657 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,14882589 0,16448098 ! methylation GO:0032259 90 47 0,000 0,14882589 0,16440546 ! Notch signaling pathway GO:0007219 96 48 0,000 0,15174145 0,1675493 ! cellular component disassembly GO:0022411 86 48 0,000 0,15174145 0,16747245 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,15174145 0,16739566 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,15174145 0,16731894 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,15174145 0,1672423 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,15174145 0,16716572 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,15174145 0,16708921 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,15464712 0,17021088 ! regulation of action potential GO:0001508 95 49 0,000 0,15464712 0,17013305 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,15464712 0,17005529 ! regulation of ion transport GO:0043269 77 49 0,000 0,15464712 0,16997761 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,15464712 0,16989999 ! peptide metabolic process GO:0006518 76 49 0,000 0,15464712 0,16982245 ! response to temperature stimulus GO:0009266 76 49 0,000 0,15464712 0,16974497 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,15464712 0,16966757 ! endocrine system development GO:0035270 104 49 0,000 0,15464712 0,16959024 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,15464712 0,16951297 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,15464712 0,16943578 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,15464712 0,16935866 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,15464712 0,16928161 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,15754294 0,17237304 ! regulation of ossification GO:0030278 117 50 0,000 0,15754294 0,17229469 ! inner ear development GO:0048839 79 50 0,000 0,15754294 0,17221641 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,15754294 0,1721382 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,15754294 0,17206006 ! viral infectious cycle GO:0019058 99 51 0,000 0,16042893 0,17513249 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,16042893 0,17505306 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,16042893 0,17497371 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,16042893 0,17489443 ! excretion GO:0007588 83 51 0,000 0,16042893 0,17481522 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,16042893 0,17473608 ! chromatin remodeling GO:0006338 109 51 0,000 0,16042893 0,17465701 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,16042893 0,17457802 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,16042893 0,1744991 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,16330513 0,17754728 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,16330513 0,17746709 ! amino acid activation GO:0043038 92 52 0,000 0,16330513 0,17738697 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,16330513 0,17730692 ! synapse organization GO:0050808 85 52 0,000 0,16330513 0,17722695 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,16617157 0,18025645 ! RNA catabolic process GO:0006401 93 53 0,000 0,16617157 0,18017521 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,16617157 0,18009405 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,16617157 0,18001297 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,16617157 0,17993195 ! cell maturation GO:0048469 100 53 0,000 0,16617157 0,17985101 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,16902829 0,18286064 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,16902829 0,18277845 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,16902829 0,18269634 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,16902829 0,18261431 ! chloride transport GO:0006821 90 55 0,000 0,17187531 0,18560682 ! glucose catabolic process GO:0006007 82 55 0,000 0,17187531 0,18552355 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,17187531 0,18544036 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,17187531 0,18535724 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,17187531 0,18527419 ! RNA elongation GO:0006354 79 55 0,000 0,17187531 0,18519122 ! nuclear export GO:0051168 97 55 0,000 0,17187531 0,18510833 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,17187531 0,1850255 ! regulation of actin filament length GO:0030832 105 56 0,000 0,17471268 0,18799584 ! sensory perception of smell GO:0007608 80 56 0,000 0,17471268 0,1879118 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,17471268 0,18782784 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,17471268 0,18774395 ! proton transport GO:0015992 94 56 0,000 0,17471268 0,18766013 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,17754041 0,19061233 ! muscle fiber development GO:0048747 112 57 0,000 0,17754041 0,19052731 ! lipid modification GO:0030258 97 57 0,000 0,17754041 0,19044237 ! maintenance of location GO:0051235 118 57 0,000 0,17754041 0,1903575 ! hydrogen transport GO:0006818 97 58 0,000 0,18035855 0,19329295 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,18035855 0,19320689 ! regulation of endocytosis GO:0030100 91 58 0,000 0,18035855 0,19312091 ! positive regulation of secretion GO:0051047 95 59 0,000 0,18316713 0,19604098 ! regulation of cellular component size GO:0032535 109 59 0,000 0,18316713 0,19595381 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,18316713 0,19586672 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,18316713 0,19577971 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,18316713 0,19569277 ! DNA catabolic process GO:0006308 86 59 0,000 0,18316713 0,19560591 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,18316713 0,19551913 ! establishment of organelle localization GO:0051656 109 59 0,000 0,18316713 0,19543243 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,18596618 0,19833095 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,18596618 0,19824308 ! regulation of heart contraction GO:0008016 110 60 0,000 0,18596618 0,19815528 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,18596618 0,19806757 ! kidney development GO:0001822 122 60 0,000 0,18596618 0,19797992 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,18875573 0,20086081 ! tRNA processing GO:0008033 89 61 0,000 0,18875573 0,20077201 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,18875573 0,20068329 ! ear development GO:0043583 103 62 0,000 0,19153581 0,2035491 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,19153581 0,20345923 ! gonad development GO:0008406 98 62 0,000 0,19153581 0,20336945 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,19153581 0,20327974 ! regulation of mitosis GO:0007088 105 63 0,000 0,19430646 0,20612934 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,19430646 0,20603849 ! detection of external stimulus GO:0009581 91 63 0,000 0,19430646 0,20594773 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,19430646 0,20585704 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,1970677 0,20869054 ! cell redox homeostasis GO:0045454 102 64 0,000 0,1970677 0,20859872 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,1970677 0,20850699 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,1970677 0,20841534 GO:0048609|reproductive process in a multicellular organism, ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,19981958 0,21123282 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,19981958 0,21114005 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,19981958 0,21104737 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,19981958 0,21095476 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,20256211 0,21375633 ! actin filament organization GO:0007015 148 66 0,000 0,20256211 0,21366262 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,20256211 0,21356899 ! extracellular matrix organization GO:0030198 133 66 0,000 0,20256211 0,21347544 ! secondary metabolic process GO:0019748 116 66 0,000 0,20256211 0,21338198 ! developmental maturation GO:0021700 116 66 0,000 0,20256211 0,21328859 ! cell projection assembly GO:0030031 120 66 0,000 0,20256211 0,21319529 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,20529533 0,21597751 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,20529533 0,21588312 ! chromosome segregation GO:0007059 113 67 0,000 0,20529533 0,2157888 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,20529533 0,21569457 ! hexose catabolic process GO:0019320 104 67 0,000 0,20529533 0,21560042 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,20529533 0,21550636 ! adaptive immune response GO:0002250 119 67 0,000 0,20529533 0,21541237 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,20529533 0,21531847 ! amino acid transport GO:0006865 125 68 0,000 0,20801928 0,21808034 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,20801928 0,21798536 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,20801928 0,21789046 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,20801928 0,21779564 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,20801928 0,21770091 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,21073398 0,22044607 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,21073398 0,22035026 ! urogenital system development GO:0001655 137 69 0,000 0,21073398 0,22025454 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,21073398 0,2201589 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,21073398 0,22006335 ! antigen processing and presentation GO:0019882 104 69 0,000 0,21073398 0,21996788 ! appendage morphogenesis GO:0035107 135 70 0,000 0,21343946 0,22269529 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,21613576 0,22541077 ! reproductive structure development GO:0048608 113 71 0,000 0,21613576 0,22531311 ! appendage development GO:0048736 136 71 0,000 0,21613576 0,22521552 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,21613576 0,22511803 ! regulation of immune effector process GO:0002697 137 71 0,000 0,21613576 0,22502062 ! acute inflammatory response GO:0002526 113 72 0,000 0,21882291 0,22771969 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,21882291 0,22762124 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,21882291 0,22752287 ! carbohydrate transport GO:0008643 110 72 0,000 0,21882291 0,22742459 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,21882291 0,22732639 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,21882291 0,22722828 ! learning or memory GO:0007611 147 73 0,000 0,22150093 0,22990994 ! regulation of blood pressure GO:0008217 125 73 0,000 0,22150093 0,2298108 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,22150093 0,22971175 ! axon guidance GO:0007411 139 73 0,000 0,22150093 0,22961277 ! transition metal ion transport GO:0000041 126 74 0,000 0,22416987 0,23227937 ! neurotransmitter transport GO:0006836 123 74 0,000 0,22416987 0,23217938 ! meiosis GO:0007126 121 74 0,000 0,22416987 0,23207947 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,22416987 0,23197966 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,22416987 0,23187992 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,22416987 0,23178027 ! organelle localization GO:0051640 136 74 0,000 0,22416987 0,23168071 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,22682974 0,23432905 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,22682974 0,23422848 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,22682974 0,23412799 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,22682974 0,23402759 ! meiotic cell cycle GO:0051321 122 75 0,000 0,22682974 0,23392728 ! rhythmic process GO:0048511 128 75 0,000 0,22682974 0,23382706 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,22948058 0,23645836 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,22948058 0,23635714 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,22948058 0,236256 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,22948058 0,23615495 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,23212242 0,2387715 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,23212242 0,23866946 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,23212242 0,23856751 ! blood coagulation GO:0007596 146 78 0,000 0,23475529 0,24117046 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,23475529 0,24106753 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,23737922 0,24365802 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,23737922 0,24355411 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,23737922 0,2434503 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,23737922 0,24334657 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,23737922 0,24324293 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,23999423 0,24581785 ! response to metal ion GO:0010038 140 80 0,000 0,23999423 0,24571325 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,23999423 0,24560873 ! inorganic anion transport GO:0015698 138 80 0,000 0,23999423 0,24550431 ! digestion GO:0007586 112 81 0,000 0,24260037 0,24806481 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,24260037 0,24795943 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,24260037 0,24785414 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,24519766 0,25040135 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,24519766 0,25029511 ! response to nutrient GO:0007584 125 82 0,000 0,24519766 0,25018896 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,24519766 0,25008291 ! regulation of lyase activity GO:0051339 160 83 0,000 0,24778613 0,25261586 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,25036581 0,25513771 ! hemostasis GO:0007599 158 84 0,000 0,25036581 0,25502969 ! negative regulation of transport GO:0051051 153 84 0,000 0,25036581 0,25492177 ! regulation of ligase activity GO:0051340 142 84 0,000 0,25036581 0,25481393 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,25036581 0,25470619 ! response to unfolded protein GO:0006986 131 85 0,000 0,25293672 0,25721292 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,25293672 0,25710425 ! amine biosynthetic process GO:0009309 138 86 0,000 0,25549891 0,25959897 ! response to inorganic substance GO:0010035 153 86 0,000 0,25549891 0,25948939 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,25549891 0,2593799 ! alcohol catabolic process GO:0046164 130 86 0,000 0,25549891 0,25927051 ! amine transport GO:0015837 155 86 0,000 0,25549891 0,2591612 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,25805239 0,26164098 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,25805239 0,26153077 ! cellular respiration GO:0045333 135 88 0,000 0,2605972 0,26399868 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,2605972 0,26388757 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,2605972 0,26377655 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,26313336 0,26623165 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,26566091 0,26867598 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,26566091 0,26856309 ! sex differentiation GO:0007548 145 90 0,000 0,26566091 0,2684503 ! sterol metabolic process GO:0016125 152 91 0,000 0,26817988 0,27088194 ! response to protein stimulus GO:0051789 149 91 0,000 0,26817988 0,27076827 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,26817988 0,27065469 ! regulation of defense response GO:0031347 149 92 0,000 0,27069028 0,27307372 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,27069028 0,27295927 ! vitamin metabolic process GO:0006766 139 92 0,000 0,27069028 0,27284492 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,27319216 0,2752514 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,27319216 0,27513618 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,27319216 0,27502106 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,27568554 0,27741506 ! female pregnancy GO:0007565 164 94 0,000 0,27568554 0,27729908 ! regulation of T cell activation GO:0050863 158 94 0,000 0,27568554 0,27718321 ! forebrain development GO:0030900 188 95 0,000 0,27817045 0,27956479 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,27817045 0,27944806 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,28064691 0,28181823 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,28064691 0,28170066 ! detection of stimulus GO:0051606 151 96 0,000 0,28064691 0,28158318 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,28311497 0,28394106 ! protein ubiquitination GO:0016567 217 97 0,000 0,28311497 0,28382275 ! hormone metabolic process GO:0042445 157 97 0,000 0,28311497 0,28370454 ! response to virus GO:0009615 160 98 0,000 0,28557463 0,28605019 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,28557463 0,28593115 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,28557463 0,28581221 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,28802594 0,2881457 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,28802594 0,28802594