pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1132-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 6,000 4,163E-11 9,576E-08 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 4,000 5,182E-08 5,959E-05 ! regulation of epithelial cell proliferation GO:0050678 71 39 5,000 7,023E-08 5,384E-05 ! cell growth GO:0016049 61 39 4,000 2,35E-06 1,351E-03 ! positive regulation of protein ubiquitination GO:0031398 8 6 2,000 3,272E-06 1,505E-03 ! regulation of protein ubiquitination GO:0031396 19 15 2,000 7,179E-05 0,02751814 ! inner ear receptor cell differentiation GO:0060113 30 16 2,000 8,8E-05 0,02891336 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 1,064E-04 0,0305969 ! peptidyl-serine modification GO:0018209 27 17 2,000 1,064E-04 0,02719724 ! mechanoreceptor differentiation GO:0042490 32 18 2,000 1,272E-04 0,02925492 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 1,504E-04 0,03145507 ! benzene and derivative metabolic process GO:0042537 11 5 1,000 3,014E-04 0,05777034 ! sleep GO:0030431 11 5 1,000 3,014E-04 0,05332647 ! rhythmic behavior GO:0007622 12 5 1,000 3,014E-04 0,04951744 ! microvillus organization GO:0032528 7 5 1,000 3,014E-04 0,04621628 GO:0030033|microvillus assembly, ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 3,014E-04 0,04332776 ! NAD biosynthetic process GO:0009435 7 5 1,000 3,014E-04 0,04077907 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 3,924E-04 0,05014491 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 3,000 4,129E-04 0,04997771 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 4,505E-04 0,05180516 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 4,505E-04 0,04933825 ! response to interferon-gamma GO:0034341 12 6 1,000 4,505E-04 0,0470956 ! cysteine metabolic process GO:0006534 7 6 1,000 4,505E-04 0,04504797 ! ER overload response GO:0006983 7 6 1,000 4,505E-04 0,04317097 ! vascular smooth muscle contraction GO:0014829 10 6 1,000 4,505E-04 0,04144413 ! positive regulation of phosphorylation GO:0042327 102 70 3,000 6,17E-04 0,05457777 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 6,284E-04 0,05352954 ! asymmetric protein localization GO:0008105 8 7 1,000 6,284E-04 0,05161777 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 1,000 6,284E-04 0,04983785 ! peptidyl-threonine modification GO:0018210 18 7 1,000 6,284E-04 0,04817659 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 1,000 6,284E-04 0,0466225 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 3,000 6,864E-04 0,04933725 GO:0045937|positive regulation of phosphate metabolic process, ! UTP metabolic process GO:0046051 8 8 1,000 8,348E-04 0,05818472 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 8,348E-04 0,0564734 ! induction of an organ GO:0001759 11 8 1,000 8,348E-04 0,05485988 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 9,528E-04 0,06087425 ! CTP metabolic process GO:0046036 9 9 1,000 1,069E-03 0,06648033 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 1,000 1,069E-03 0,06473085 ! L-serine metabolic process GO:0006563 13 9 1,000 1,069E-03 0,06307108 ! indolalkylamine metabolic process GO:0006586 14 9 1,000 1,069E-03 0,0614943 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! pyridine nucleotide biosynthetic process GO:0019363 11 9 1,000 1,069E-03 0,05999444 ! negative regulation of BMP signaling pathway GO:0030514 13 9 1,000 1,069E-03 0,058566 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 1,000 1,069E-03 0,057204 ! localization within membrane GO:0051668 15 9 1,000 1,069E-03 0,05590391 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 1,332E-03 0,06808016 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,332E-03 0,06660015 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 1,000 1,332E-03 0,06518313 ! developmental induction GO:0031128 13 10 1,000 1,332E-03 0,06382515 GO:0045168|cell-cell signaling involved in cell fate specification, ! inner ear development GO:0048839 57 40 2,000 1,41E-03 0,06617283 ! JAK-STAT cascade GO:0007259 53 40 2,000 1,41E-03 0,06484938 ! positive regulation of protein transport GO:0051222 55 40 2,000 1,41E-03 0,06357782 ! epithelial cell differentiation GO:0030855 55 41 2,000 1,515E-03 0,06700889 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 1,622E-03 0,07039409 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 1,622E-03 0,0690905 ! vasoconstriction GO:0042310 15 11 1,000 1,622E-03 0,06783431 ! aromatic amino acid family catabolic process GO:0009074 13 11 1,000 1,622E-03 0,06662298 ! serine family amino acid biosynthetic process GO:0009070 13 11 1,000 1,622E-03 0,06545415 ! biogenic amine catabolic process GO:0042402 21 11 1,000 1,622E-03 0,06432563 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 1,625E-03 0,06334737 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 1,783E-03 0,06834488 ! cartilage condensation GO:0001502 18 12 1,000 1,94E-03 0,07312956 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 1,000 1,94E-03 0,07195005 ! histone acetylation GO:0016573 23 12 1,000 1,94E-03 0,07080799 ! gland morphogenesis GO:0022612 23 12 1,000 1,94E-03 0,06970161 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,94E-03 0,06862928 ! regulation of fatty acid oxidation GO:0046320 18 12 1,000 1,94E-03 0,06758944 ! positive regulation of cell cycle GO:0045787 77 45 2,000 1,985E-03 0,06812856 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 2,284E-03 0,07724933 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 1,000 2,284E-03 0,07612977 ! NAD metabolic process GO:0019674 21 13 1,000 2,284E-03 0,0750422 ! intermediate filament cytoskeleton organization GO:0045104 23 13 1,000 2,284E-03 0,07398527 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 2,284E-03 0,0729577 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 2,284E-03 0,07195828 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 2,000 2,39E-03 0,0742886 ! regulation of intracellular transport GO:0032386 78 49 2,000 2,536E-03 0,07776675 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 2,655E-03 0,08034662 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 1,000 2,655E-03 0,07930316 ! intermediate filament-based process GO:0045103 24 14 1,000 2,655E-03 0,07828645 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 2,655E-03 0,07729548 ! ear development GO:0043583 72 50 2,000 2,687E-03 0,07725042 ! sulfur amino acid biosynthetic process GO:0000097 17 15 1,000 3,052E-03 0,08667135 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 3,052E-03 0,08561438 ! myoblast differentiation GO:0045445 27 15 1,000 3,052E-03 0,08458288 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 1,000 3,052E-03 0,08357594 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 3,052E-03 0,0825927 ! cellular amino acid derivative catabolic process GO:0042219 27 15 1,000 3,052E-03 0,08163232 ! regulation of BMP signaling pathway GO:0030510 21 15 1,000 3,052E-03 0,08069401 ! protein amino acid acetylation GO:0006473 28 16 1,000 3,476E-03 0,09084519 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 1,000 3,476E-03 0,08982446 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 1,000 3,476E-03 0,08882641 ! G1 phase GO:0051318 27 16 1,000 3,476E-03 0,0878503 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 1,000 3,476E-03 0,0868954 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 3,925E-03 0,09707159 ! aromatic compound catabolic process GO:0019439 22 17 1,000 3,925E-03 0,09603891 ! lung development GO:0030324 94 59 2,000 4,299E-03 0,104089 ! somitogenesis GO:0001756 24 18 1,000 4,4E-03 0,10541194 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 4,4E-03 0,10432522 ! cell-matrix adhesion GO:0007160 114 61 2,000 4,722E-03 0,11081955 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 4,9E-03 0,11383206 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 4,9E-03 0,11269374 ! smooth muscle contraction GO:0006939 36 19 1,000 4,9E-03 0,11157796 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 4,9E-03 0,11048406 ! aromatic amino acid family metabolic process GO:0009072 24 19 1,000 4,9E-03 0,1094114 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 1,000 4,9E-03 0,10835937 ! respiratory tube development GO:0030323 99 62 2,000 4,942E-03 0,10825834 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 2,000 5,401E-03 0,11719863 ! respiratory system development GO:0060541 100 64 2,000 5,401E-03 0,11610332 ! protein amino acid O-linked glycosylation GO:0006493 29 20 1,000 5,425E-03 0,11552296 ! response to vitamin GO:0033273 29 20 1,000 5,425E-03 0,11446311 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 5,425E-03 0,11342254 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 1,000 5,425E-03 0,11240071 ! cell-substrate adhesion GO:0031589 121 66 2,000 5,885E-03 0,12085802 ! sulfur amino acid metabolic process GO:0000096 24 21 1,000 5,974E-03 0,12159472 ! gluconeogenesis GO:0006094 25 21 1,000 5,974E-03 0,1205281 ! protein amino acid acylation GO:0043543 37 21 1,000 5,974E-03 0,11948003 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 5,974E-03 0,11845003 ! response to cytokine stimulus GO:0034097 47 21 1,000 5,974E-03 0,11743763 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 1,000 5,974E-03 0,1164424 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 6,548E-03 0,12655373 ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 6,548E-03 0,12549912 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 6,548E-03 0,12446193 GO:0010810|regulation of cell-substrate adhesion, ! vitamin biosynthetic process GO:0009110 24 22 1,000 6,548E-03 0,12344176 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 7,146E-03 0,13361711 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 7,146E-03 0,13253956 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 7,146E-03 0,13147924 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 7,146E-03 0,13043575 ! pyruvate metabolic process GO:0006090 29 24 1,000 7,767E-03 0,1406661 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 7,767E-03 0,13956715 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 7,767E-03 0,13848523 ! cofactor biosynthetic process GO:0051188 92 75 2,000 8,379E-03 0,14824501 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 8,412E-03 0,14769715 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 8,412E-03 0,14657823 ! regulation of chromosome organization GO:0033044 35 25 1,000 8,412E-03 0,14547614 ! positive regulation of nuclear division GO:0051785 39 25 1,000 8,412E-03 0,1443905 GO:0045840|positive regulation of mitosis, ! regulation of protein transport GO:0051223 114 76 2,000 8,689E-03 0,14803177 GO:0070201|regulation of establishment of protein localization, ! circadian rhythm GO:0007623 42 26 1,000 9,081E-03 0,15356963 ! negative regulation of protein modification process GO:0031400 50 26 1,000 9,081E-03 0,15244868 ! nicotinamide metabolic process GO:0006769 39 26 1,000 9,081E-03 0,15134398 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of protein modification process GO:0031401 107 78 2,000 9,328E-03 0,15435354 ! alkaloid metabolic process GO:0009820 40 27 1,000 9,772E-03 0,16053856 ! serine family amino acid metabolic process GO:0009069 37 27 1,000 9,772E-03 0,15939999 ! forebrain development GO:0030900 131 80 2,000 9,995E-03 0,16188548 ! pyridine nucleotide metabolic process GO:0019362 41 28 1,000 0,01048587 0,16865379 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01122223 0,179244 ! hexose biosynthetic process GO:0019319 35 29 1,000 0,01122223 0,17800783 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 0,01177934 0,18556492 ! regulation of protein localization GO:0032880 132 85 2,000 0,01177934 0,18430257 ! spindle organization GO:0007051 37 30 1,000 0,01198075 0,18618728 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 0,01215682 0,18765567 ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,01254121 0,19229854 GO:0060538|skeletal muscle organ development, ! mammary gland development GO:0030879 57 31 1,000 0,01276115 0,19437506 ! xenobiotic metabolic process GO:0006805 44 31 1,000 0,01276115 0,19309628 ! segmentation GO:0035282 41 31 1,000 0,01276115 0,19183421 ! cell fate specification GO:0001708 37 31 1,000 0,01276115 0,19058853 ! leukocyte chemotaxis GO:0030595 43 31 1,000 0,01276115 0,18935893 GO:0060326|cell chemotaxis, ! interphase GO:0051325 159 88 2,000 0,01293251 0,19067167 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,01356317 0,19869608 ! meiosis I GO:0007127 52 32 1,000 0,01356317 0,19743851 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,01356317 0,19619676 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 0,01356317 0,19497053 ! sister chromatid segregation GO:0000819 46 33 1,000 0,01438655 0,20552219 ! cytokinesis GO:0000910 52 33 1,000 0,01438655 0,20425354 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 1,000 0,01438655 0,20300045 ! establishment or maintenance of cell polarity GO:0007163 61 34 1,000 0,01523105 0,21360615 ! angiogenesis GO:0001525 149 95 2,000 0,01586674 0,22117269 ! glycogen metabolic process GO:0005977 48 35 1,000 0,01609639 0,22302234 ! protein homooligomerization GO:0051260 52 35 1,000 0,01609639 0,22168688 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01698234 0,23249637 GO:0090047|positive regulation of transcription regulator activity, ! cellular amide metabolic process GO:0043603 52 36 1,000 0,01698234 0,23112065 ! tissue remodeling GO:0048771 62 36 1,000 0,01698234 0,22976112 ! response to xenobiotic stimulus GO:0009410 50 36 1,000 0,01698234 0,22841748 ! glucan metabolic process GO:0044042 49 36 1,000 0,01698234 0,22708947 GO:0006073|cellular glucan metabolic process, ! ribonucleoside metabolic process GO:0009119 48 37 1,000 0,01788864 0,23782588 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 1,000 0,01788864 0,23645907 ! gliogenesis GO:0042063 71 38 1,000 0,01881504 0,24728343 ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,01881504 0,24587841 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 0,0197613 0,25678528 ! regulation of tube size GO:0035150 60 40 1,000 0,02072717 0,26782301 GO:0050880|regulation of blood vessel size, ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,02072717 0,26632679 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,02171241 0,27743638 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,02171241 0,27590358 ! mitochondrial transport GO:0006839 60 42 1,000 0,02271678 0,28708023 ! positive regulation of binding GO:0051099 59 43 1,000 0,02374005 0,29837216 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 0,02374005 0,29675058 ! leukocyte migration GO:0050900 60 43 1,000 0,02374005 0,29514652 ! cellular amino acid biosynthetic process GO:0008652 51 44 1,000 0,02478197 0,30644366 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,02584231 0,31784656 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,02584231 0,31615589 ! regulation of ossification GO:0030278 71 46 1,000 0,02692084 0,3276081 ! histone modification GO:0016570 68 46 1,000 0,02692084 0,32588385 ! response to UV GO:0009411 75 46 1,000 0,02692084 0,32417765 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02743976 0,3287055 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02743976 0,32700236 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02743976 0,32531678 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02743976 0,32364849 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02743976 0,32199723 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02743976 0,32036272 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02743976 0,31874473 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02743976 0,317143 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02743976 0,31555728 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02743976 0,31398734 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02743976 0,31243295 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02743976 0,31089387 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02743976 0,30936988 ! tongue development GO:0043586 6 5 0,000 0,02743976 0,30786076 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02743976 0,30636629 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02743976 0,30488626 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02743976 0,30342046 ! cobalt ion transport GO:0006824 9 5 0,000 0,02743976 0,30196869 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02743976 0,30053074 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02743976 0,29910643 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02743976 0,29769555 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02743976 0,29629792 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02743976 0,29491335 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02743976 0,29354166 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02743976 0,29218267 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02743976 0,2908362 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02743976 0,28950209 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02743976 0,28818017 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02743976 0,28687026 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02743976 0,2855722 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,02743976 0,28428584 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02743976 0,28301101 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02743976 0,28174757 ! malate metabolic process GO:0006108 7 5 0,000 0,02743976 0,28049536 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02743976 0,27925423 ! behavioral response to pain GO:0048266 7 5 0,000 0,02743976 0,27802404 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02743976 0,27680463 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02743976 0,27559588 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02743976 0,27439764 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02743976 0,27320977 ! mating behavior GO:0007617 6 5 0,000 0,02743976 0,27203214 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02743976 0,27086462 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02743976 0,26970708 ! copulation GO:0007620 7 5 0,000 0,02743976 0,26855939 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02743976 0,26742142 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02743976 0,26629306 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02743976 0,26517419 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02743976 0,26406467 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02743976 0,2629644 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02743976 0,26187326 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02743976 0,26079114 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02743976 0,25971793 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02743976 0,25865351 ! response to protozoan GO:0001562 9 5 0,000 0,02743976 0,25759778 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02743976 0,25655063 ! lymph vessel development GO:0001945 7 5 0,000 0,02743976 0,25551197 ! endochondral ossification GO:0001958 12 5 0,000 0,02743976 0,25448168 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02743976 0,25345966 ! parathyroid gland development GO:0060017 8 5 0,000 0,02743976 0,25244582 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02743976 0,25144006 ! anagen GO:0042640 6 5 0,000 0,02743976 0,25044229 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02743976 0,2494524 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02743976 0,2484703 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02743976 0,24749591 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02743976 0,24652913 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02743976 0,24556987 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02743976 0,24461805 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02743976 0,24367358 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02743976 0,24273637 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02743976 0,24180635 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02743976 0,24088342 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02743976 0,23996751 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02743976 0,23905855 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,02743976 0,23815644 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02743976 0,23726111 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02743976 0,2363725 ! ovulation GO:0030728 6 5 0,000 0,02743976 0,23549051 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02743976 0,23461508 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,02743976 0,23374613 ! response to pH GO:0009268 9 5 0,000 0,02743976 0,2328836 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02743976 0,23202741 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02743976 0,2311775 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02743976 0,23033378 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02743976 0,2294962 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02743976 0,2286647 ! polyol catabolic process GO:0046174 7 5 0,000 0,02743976 0,22783919 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02743976 0,22701963 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02743976 0,22620594 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02743976 0,22539806 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02743976 0,22459593 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02743976 0,22379949 ! urea metabolic process GO:0019627 6 5 0,000 0,02743976 0,22300868 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02743976 0,22222344 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02743976 0,22144371 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02743976 0,22066943 ! neutrophil activation GO:0042119 5 5 0,000 0,02743976 0,21990054 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02743976 0,219137 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02743976 0,21837874 ! response to food GO:0032094 5 5 0,000 0,02743976 0,21762571 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02743976 0,21687786 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02743976 0,21613512 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02743976 0,21539746 ! forebrain neuron development GO:0021884 7 5 0,000 0,02743976 0,21466482 ! melanosome organization GO:0032438 7 5 0,000 0,02743976 0,21393714 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02743976 0,21321438 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02743976 0,21249649 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02743976 0,21178341 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02743976 0,2110751 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02743976 0,21037152 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02743976 0,20967261 ! nucleoside transport GO:0015858 6 5 0,000 0,02743976 0,20897833 ! nucleoside salvage GO:0043174 7 5 0,000 0,02743976 0,20828863 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02743976 0,20760347 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02743976 0,20692281 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02743976 0,20624659 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02743976 0,20557478 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02743976 0,20490733 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02743976 0,20424419 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02743976 0,20358534 ! depyrimidination GO:0045008 8 5 0,000 0,02743976 0,20293073 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02743976 0,20228031 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02743976 0,20163405 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02743976 0,2009919 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02743976 0,20035383 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02743976 0,1997198 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02743976 0,19908977 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02743976 0,1984637 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02743976 0,19784156 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02743976 0,1972233 ! monocyte differentiation GO:0030224 8 5 0,000 0,02743976 0,1966089 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02743976 0,19599831 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02743976 0,19539151 ! centrosome duplication GO:0051298 5 5 0,000 0,02743976 0,19478845 ! response to UV-C GO:0010225 6 5 0,000 0,02743976 0,1941891 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02743976 0,19359342 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02743976 0,1930014 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02743976 0,19241298 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02743976 0,19182813 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02743976 0,19124684 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02743976 0,19066905 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02743976 0,19009475 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02743976 0,18952389 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02743976 0,18895646 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02743976 0,18839241 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02743976 0,18783171 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02743976 0,18727435 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02743976 0,18672028 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02743976 0,18616949 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02743976 0,18562193 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02743976 0,18507758 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02743976 0,18453642 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02743976 0,18399841 ! neural tube patterning GO:0021532 6 5 0,000 0,02743976 0,18346354 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02743976 0,18293176 ! histone demethylation GO:0016577 9 5 0,000 0,02743976 0,18240305 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02743976 0,1818774 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02743976 0,18135476 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02743976 0,18083512 ! enteric nervous system development GO:0048484 8 5 0,000 0,02743976 0,18031845 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02743976 0,17980472 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02743976 0,17929391 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02743976 0,17878599 ! transcription termination GO:0006353 8 5 0,000 0,02743976 0,17828095 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02743976 0,17777875 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02743976 0,17727937 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02743976 0,17678279 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02743976 0,17628898 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02743976 0,17579793 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02743976 0,1753096 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02743976 0,17482398 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02743976 0,17434104 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02743976 0,17386076 ! apical protein localization GO:0045176 6 5 0,000 0,02743976 0,17338312 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02743976 0,1729081 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02743976 0,17243567 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02743976 0,17196582 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02743976 0,17149852 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02743976 0,17103376 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02743976 0,1705715 ! glial cell migration GO:0008347 10 5 0,000 0,02743976 0,17011174 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02743976 0,16965445 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02743976 0,16919961 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02743976 0,16874721 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02743976 0,16829722 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02743976 0,16784962 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02743976 0,16740439 ! neural plate development GO:0001840 6 5 0,000 0,02743976 0,16696152 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,02743976 0,16652099 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02743976 0,16608278 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02743976 0,16564687 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02743976 0,16521324 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02743976 0,16478187 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02743976 0,16435275 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02743976 0,16392586 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02743976 0,16350118 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02743976 0,1630787 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02743976 0,16265839 ! spindle assembly GO:0051225 5 5 0,000 0,02743976 0,16224025 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02743976 0,16182425 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02743976 0,16141037 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02743976 0,16099861 ! organ regeneration GO:0031100 7 5 0,000 0,02743976 0,16058895 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02743976 0,16018136 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02743976 0,15977584 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02743976 0,15937236 GO:0055081|anion homeostasis, ! covalent chromatin modification GO:0016569 75 47 1,000 0,02801733 0,16231704 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,02913156 0,1683482 ! sulfur compound biosynthetic process GO:0044272 62 49 1,000 0,03026329 0,17445004 ! heterocycle catabolic process GO:0046700 72 49 1,000 0,03026329 0,17401391 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,03026329 0,17357996 ! cartilage development GO:0051216 70 49 1,000 0,03026329 0,17314817 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,0314123 0,17927617 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 0,03257838 0,18547095 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,03257838 0,18501299 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,03257838 0,1845573 ! positive regulation of cell migration GO:0030335 92 51 1,000 0,03257838 0,18410384 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,03257838 0,18365261 ! tRNA transcription GO:0009304 11 6 0,000 0,03283762 0,18466143 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03283762 0,18421104 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03283762 0,18376284 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03283762 0,18331681 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03283762 0,18287295 ! regulation of helicase activity GO:0051095 11 6 0,000 0,03283762 0,18243122 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03283762 0,18199163 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,03283762 0,18155415 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03283762 0,18111877 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03283762 0,18068547 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03283762 0,18025424 ! prostate gland development GO:0030850 9 6 0,000 0,03283762 0,17982506 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03283762 0,17939793 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03283762 0,17897281 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03283762 0,17854971 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,03283762 0,1781286 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03283762 0,17770947 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03283762 0,17729232 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03283762 0,17687711 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03283762 0,17646385 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03283762 0,17605251 ! neuron adhesion GO:0007158 9 6 0,000 0,03283762 0,17564309 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03283762 0,17523556 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03283762 0,17482992 ! signal peptide processing GO:0006465 8 6 0,000 0,03283762 0,17442616 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03283762 0,17402426 ! mRNA stabilization GO:0048255 15 6 0,000 0,03283762 0,1736242 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03283762 0,17322598 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03283762 0,17282958 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03283762 0,17243499 ! opsonization GO:0008228 8 6 0,000 0,03283762 0,1720422 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03283762 0,1716512 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03283762 0,17126197 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03283762 0,17087449 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03283762 0,17048877 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03283762 0,17010479 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03283762 0,16972253 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03283762 0,16934199 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03283762 0,16896315 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03283762 0,168586 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03283762 0,16821053 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03283762 0,16783673 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03283762 0,16746458 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03283762 0,16709409 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03283762 0,16672522 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03283762 0,16635799 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03283762 0,16599237 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03283762 0,16562835 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,03283762 0,16526592 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03283762 0,16490508 ! thymic T cell selection GO:0045061 12 6 0,000 0,03283762 0,16454581 ! protein lipoylation GO:0009249 10 6 0,000 0,03283762 0,1641881 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,03283762 0,16383195 ! pigment granule organization GO:0048753 11 6 0,000 0,03283762 0,16347733 ! drug transport GO:0015893 6 6 0,000 0,03283762 0,16312425 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,03283762 0,16277269 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03283762 0,16242264 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03283762 0,16207409 ! histidine metabolic process GO:0006547 6 6 0,000 0,03283762 0,16172704 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03283762 0,16138147 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03283762 0,16103737 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03283762 0,16069474 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03283762 0,16035356 ! adenohypophysis development GO:0021984 10 6 0,000 0,03283762 0,16001383 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03283762 0,15967553 ! hyperosmotic response GO:0006972 8 6 0,000 0,03283762 0,15933866 ! microtubule nucleation GO:0007020 10 6 0,000 0,03283762 0,15900321 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03283762 0,15866917 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03283762 0,15833653 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03283762 0,15800529 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03283762 0,15767542 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,03283762 0,15734693 ! response to dietary excess GO:0002021 7 6 0,000 0,03283762 0,15701981 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03283762 0,15669404 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,03283762 0,15636962 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03283762 0,15604654 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03283762 0,1557248 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03283762 0,15540438 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03283762 0,15508527 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03283762 0,15476747 ! neuron apoptosis GO:0051402 8 6 0,000 0,03283762 0,15445098 ! organic alcohol transport GO:0015850 9 6 0,000 0,03283762 0,15413577 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03283762 0,15382185 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03283762 0,1535092 ! male sex determination GO:0030238 9 6 0,000 0,03283762 0,15319782 ! carnitine transport GO:0015879 8 6 0,000 0,03283762 0,15288771 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03283762 0,15257884 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03283762 0,15227122 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03283762 0,15196484 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03283762 0,15165969 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03283762 0,15135577 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03283762 0,15105305 ! parturition GO:0007567 12 6 0,000 0,03283762 0,15075155 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03283762 0,15045125 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03283762 0,15015214 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03283762 0,14985422 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,03283762 0,14955748 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,03283762 0,14926191 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03283762 0,14896751 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03283762 0,14867427 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03283762 0,14838217 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03283762 0,14809123 ! macrophage differentiation GO:0030225 10 6 0,000 0,03283762 0,14780142 ! astrocyte development GO:0014002 14 6 0,000 0,03283762 0,14751275 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03283762 0,1472252 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03283762 0,14693877 ! interaction with symbiont GO:0051702 8 6 0,000 0,03283762 0,14665345 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03283762 0,14636924 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03283762 0,14608613 ! eating behavior GO:0042755 6 6 0,000 0,03283762 0,14580411 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03283762 0,14552317 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03283762 0,14524332 ! response to copper ion GO:0046688 9 6 0,000 0,03283762 0,14496454 ! DNA topological change GO:0006265 8 6 0,000 0,03283762 0,14468683 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03283762 0,14441019 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,03283762 0,14413459 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03283762 0,14386005 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03283762 0,14358655 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03283762 0,14331409 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03283762 0,14304266 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03283762 0,14277226 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03283762 0,14250288 ! gas homeostasis GO:0033483 11 6 0,000 0,03283762 0,14223451 ! hair follicle maturation GO:0048820 7 6 0,000 0,03283762 0,14196716 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03283762 0,1417008 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03283762 0,14143544 ! Schwann cell development GO:0014044 14 6 0,000 0,03283762 0,14117108 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03283762 0,1409077 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03283762 0,1406453 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03283762 0,14038388 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03283762 0,14012343 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,03283762 0,13986394 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03283762 0,13960541 ! histone ubiquitination GO:0016574 7 6 0,000 0,03283762 0,13934784 ! regulation of meiosis GO:0040020 10 6 0,000 0,03283762 0,13909121 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03283762 0,13883553 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03283762 0,13858078 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03283762 0,13832697 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03283762 0,13807409 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03283762 0,13782213 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03283762 0,13757109 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03283762 0,13732096 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03283762 0,13707174 ! receptor internalization GO:0031623 9 6 0,000 0,03283762 0,13682342 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,03283762 0,136576 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03283762 0,13632947 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03283762 0,13608383 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,03283762 0,13583908 ! protein deubiquitination GO:0016579 8 6 0,000 0,03283762 0,1355952 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03283762 0,1353522 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,03283762 0,13511007 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03283762 0,1348688 ! axonal fasciculation GO:0007413 9 6 0,000 0,03283762 0,13462839 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03283762 0,13438884 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03283762 0,13415014 ! midbrain development GO:0030901 6 6 0,000 0,03283762 0,13391228 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03283762 0,13367527 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03283762 0,13343909 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,03283762 0,13320375 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03283762 0,13296924 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03283762 0,13273555 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03283762 0,13250268 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03283762 0,13227062 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03283762 0,13203938 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03283762 0,13180895 ! adult feeding behavior GO:0008343 6 6 0,000 0,03283762 0,13157931 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03283762 0,13135048 ! blastocyst growth GO:0001832 15 6 0,000 0,03283762 0,13112244 ! pigment granule transport GO:0051904 12 6 0,000 0,03283762 0,13089519 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03283762 0,13066873 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03283762 0,13044305 ! catecholamine transport GO:0051937 7 6 0,000 0,03283762 0,13021815 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03283762 0,12999402 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03283762 0,12977066 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03283762 0,12954807 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,03283762 0,12932624 ! protein prenylation GO:0018342 10 6 0,000 0,03283762 0,12910517 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03283762 0,12888486 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,03283762 0,12866529 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03283762 0,12844647 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03283762 0,1282284 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03283762 0,12801106 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,03376129 0,1313891 ! establishment of organelle localization GO:0051656 85 52 1,000 0,03376129 0,13116716 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,03496082 0,13559846 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,03496082 0,13537018 ! cell projection assembly GO:0030031 76 53 1,000 0,03496082 0,13514267 ! regulation of mitosis GO:0007088 84 54 1,000 0,03617676 0,13960829 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,03617676 0,13937444 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,03617676 0,13914137 ! cellular amino acid catabolic process GO:0009063 74 54 1,000 0,03617676 0,13890908 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,03617676 0,13867757 ! nucleoside metabolic process GO:0009116 69 55 1,000 0,03740888 0,14316211 ! water-soluble vitamin metabolic process GO:0006767 71 55 1,000 0,03740888 0,1429243 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,03820583 0,14572703 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03820583 0,14548576 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03820583 0,14524529 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,03820583 0,14500561 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03820583 0,14476672 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03820583 0,14452862 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,03820583 0,14429129 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03820583 0,14405475 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,03820583 0,14381898 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03820583 0,14358398 ! reproductive behavior GO:0019098 12 7 0,000 0,03820583 0,14334975 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03820583 0,14311628 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,03820583 0,14288357 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,03820583 0,14265162 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,03820583 0,14242042 ! oligopeptide transport GO:0006857 11 7 0,000 0,03820583 0,14218996 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03820583 0,14196026 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03820583 0,14173129 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,03820583 0,14150306 ! RNA methylation GO:0001510 11 7 0,000 0,03820583 0,14127556 ! pericardium development GO:0060039 8 7 0,000 0,03820583 0,14104879 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03820583 0,14082275 ! fibril organization GO:0043206 13 7 0,000 0,03820583 0,14059744 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,03820583 0,14037284 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03820583 0,14014896 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,03820583 0,13992579 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03820583 0,13970334 ! lipoprotein transport GO:0042953 9 7 0,000 0,03820583 0,13948158 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03820583 0,13926054 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03820583 0,13904019 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03820583 0,13882053 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03820583 0,13860157 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03820583 0,1383833 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03820583 0,13816572 ! chemosensory behavior GO:0007635 9 7 0,000 0,03820583 0,13794882 ! microtubule bundle formation GO:0001578 8 7 0,000 0,03820583 0,1377326 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,03820583 0,13751706 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03820583 0,13730218 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03820583 0,13708798 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03820583 0,13687445 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03820583 0,13666158 ! reflex GO:0060004 12 7 0,000 0,03820583 0,13644938 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03820583 0,13623783 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03820583 0,13602693 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03820583 0,13581669 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03820583 0,1356071 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,03820583 0,13539815 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03820583 0,13518984 ! spinal cord patterning GO:0021511 7 7 0,000 0,03820583 0,13498218 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,03820583 0,13477515 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,03820583 0,13456876 ! adrenal gland development GO:0030325 17 7 0,000 0,03820583 0,13436299 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03820583 0,13415786 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03820583 0,13395335 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03820583 0,13374946 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03820583 0,1335462 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03820583 0,13334355 ! endosome organization GO:0007032 10 7 0,000 0,03820583 0,13314151 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03820583 0,13294009 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03820583 0,13273927 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03820583 0,13253906 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03820583 0,13233946 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03820583 0,13214045 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,03820583 0,13194204 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03820583 0,13174423 ! galactose metabolic process GO:0006012 10 7 0,000 0,03820583 0,131547 ! vesicle fusion GO:0006906 15 7 0,000 0,03820583 0,13135037 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03820583 0,13115433 GO:0045851|pH reduction, ! organ growth GO:0035265 11 7 0,000 0,03820583 0,13095886 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03820583 0,13076399 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,03820583 0,13056969 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03820583 0,13037596 ! retinol metabolic process GO:0042572 9 7 0,000 0,03820583 0,13018281 ! behavioral fear response GO:0001662 13 7 0,000 0,03820583 0,12999023 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,03820583 0,12979822 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03820583 0,12960678 ! rRNA modification GO:0000154 12 7 0,000 0,03820583 0,1294159 ! protein heterooligomerization GO:0051291 10 7 0,000 0,03820583 0,12922559 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03820583 0,12903583 ! response to UV-B GO:0010224 11 7 0,000 0,03820583 0,12884663 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,03820583 0,12865798 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03820583 0,12846988 ! intermediate filament organization GO:0045109 11 7 0,000 0,03820583 0,12828233 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,03820583 0,12809533 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03820583 0,12790888 ! fibrinolysis GO:0042730 9 7 0,000 0,03820583 0,12772296 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,03820583 0,12753759 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03820583 0,12735275 ! B cell lineage commitment GO:0002326 17 7 0,000 0,03820583 0,12716845 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03820583 0,12698468 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03820583 0,12680144 ! response to tropane GO:0014073 13 7 0,000 0,03820583 0,12661873 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,03820583 0,12643654 ! melanosome localization GO:0032400 10 7 0,000 0,03820583 0,12625488 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03820583 0,12607374 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03820583 0,12589312 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03820583 0,12571302 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03820583 0,12553343 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03820583 0,12535435 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03820583 0,12517578 ! mast cell activation GO:0045576 9 7 0,000 0,03820583 0,12499772 ! multicellular organismal aging GO:0010259 11 7 0,000 0,03820583 0,12482017 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,03820583 0,12464312 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03820583 0,12446657 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03820583 0,12429052 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,03820583 0,12411497 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,03820583 0,12393991 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,03820583 0,12376535 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03820583 0,12359128 ! T cell lineage commitment GO:0002360 12 7 0,000 0,03820583 0,12341769 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,03820583 0,1232446 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03820583 0,12307199 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03820583 0,12289986 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03820583 0,12272821 ! response to tumor cell GO:0002347 12 7 0,000 0,03820583 0,12255704 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03820583 0,12238635 ! neuroblast proliferation GO:0007405 13 7 0,000 0,03820583 0,12221613 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03820583 0,12204639 ! diuresis GO:0030146 12 7 0,000 0,03820583 0,12187711 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03820583 0,12170831 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03820583 0,12153997 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03820583 0,1213721 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03820583 0,12120469 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03820583 0,12103774 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03820583 0,12087125 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03820583 0,12070522 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03820583 0,12053964 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03820583 0,12037452 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03820583 0,12020985 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03820583 0,12004563 ! lymph node development GO:0048535 9 7 0,000 0,03820583 0,11988185 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,03820583 0,11971853 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03820583 0,11955564 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,03820583 0,1193932 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03820583 0,11923121 ! ATP catabolic process GO:0006200 10 7 0,000 0,03820583 0,11906965 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03820583 0,11890852 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,03820583 0,11874784 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03820583 0,11858758 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03820583 0,11842776 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03820583 0,11826837 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03820583 0,11810941 ! muscle adaptation GO:0043500 12 7 0,000 0,03820583 0,11795087 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03820583 0,11779276 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03820583 0,11763507 ! retina homeostasis GO:0001895 9 7 0,000 0,03820583 0,11747781 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03820583 0,11732096 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,03820583 0,11716453 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,03820583 0,11700852 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,03820583 0,11685292 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03820583 0,11669774 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03820583 0,11654297 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03820583 0,11638861 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,03865698 0,11760723 ! positive regulation of cell motion GO:0051272 99 56 1,000 0,03865698 0,11745187 ! chromosome segregation GO:0007059 83 57 1,000 0,03992085 0,12113187 ! coenzyme biosynthetic process GO:0009108 67 57 1,000 0,03992085 0,12097227 ! secondary metabolic process GO:0019748 84 57 1,000 0,03992085 0,1208131 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,04354454 0,13160636 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,04354454 0,13143365 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,04354454 0,13126139 ! axon extension GO:0048675 11 8 0,000 0,04354454 0,13108958 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,04354454 0,13091822 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,04354454 0,13074731 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,04354454 0,13057685 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,04354454 0,13040682 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,04354454 0,13023725 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,04354454 0,13006811 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,04354454 0,12989941 ! phosphate transport GO:0006817 10 8 0,000 0,04354454 0,12973114 ! N-glycan processing GO:0006491 12 8 0,000 0,04354454 0,12956331 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,04354454 0,12939592 ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,04354454 0,12922896 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,04354454 0,12906242 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,04354454 0,12889632 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,04354454 0,12873064 ! succinate metabolic process GO:0006105 14 8 0,000 0,04354454 0,12856539 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,04354454 0,12840057 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04354454 0,12823616 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,04354454 0,12807218 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,04354454 0,12790861 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,04354454 0,12774546 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,04354454 0,12758273 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,04354454 0,12742041 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04354454 0,1272585 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,04354454 0,12709701 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,04354454 0,12693592 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,04354454 0,12677524 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,04354454 0,12661497 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,04354454 0,1264551 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,04354454 0,12629564 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,04354454 0,12613658 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,04354454 0,12597791 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,04354454 0,12581965 ! astrocyte differentiation GO:0048708 16 8 0,000 0,04354454 0,12566178 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,04354454 0,12550431 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,04354454 0,12534724 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,04354454 0,12519055 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,04354454 0,12503426 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,04354454 0,12487836 ! melanin metabolic process GO:0006582 12 8 0,000 0,04354454 0,12472284 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,04354454 0,12456771 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04354454 0,12441297 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,04354454 0,12425861 ! macrophage activation GO:0042116 12 8 0,000 0,04354454 0,12410464 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,04354454 0,12395104 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,04354454 0,12379783 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,04354454 0,12364499 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,04354454 0,12349253 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04354454 0,12334045 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,04354454 0,12318873 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,04354454 0,1230374 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,04354454 0,12288643 ! ruffle organization GO:0031529 11 8 0,000 0,04354454 0,12273584 ! osteoblast development GO:0002076 13 8 0,000 0,04354454 0,12258561 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,04354454 0,12243575 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,04354454 0,12228625 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,04354454 0,12213712 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,04354454 0,12198836 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,04354454 0,12183995 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,04354454 0,12169191 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,04354454 0,12154423 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,04354454 0,1213969 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,04354454 0,12124993 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,04354454 0,12110332 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,04354454 0,12095705 ! oligodendrocyte development GO:0014003 8 8 0,000 0,04354454 0,12081115 ! segment specification GO:0007379 10 8 0,000 0,04354454 0,12066559 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,04354454 0,12052039 ! cellular extravasation GO:0045123 11 8 0,000 0,04354454 0,12037553 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,04354454 0,12023102 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,04354454 0,12008686 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,04354454 0,11994304 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,04354454 0,11979957 ! snRNA metabolic process GO:0016073 10 8 0,000 0,04354454 0,11965644 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,04354454 0,11951365 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,04354454 0,11937121 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,04354454 0,1192291 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,04354454 0,11908733 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,04354454 0,11894589 ! nucleosome disassembly GO:0006337 12 8 0,000 0,04354454 0,11880479 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,04354454 0,11866403 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,04354454 0,1185236 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,04354454 0,1183835 ! icosanoid secretion GO:0032309 12 8 0,000 0,04354454 0,11824373 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04354454 0,11810429 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,04354454 0,11796518 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,04354454 0,1178264 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,04354454 0,11768795 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,04354454 0,11754981 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,04354454 0,11741201 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,04354454 0,11727452 ! sterol catabolic process GO:0016127 9 8 0,000 0,04354454 0,11713736 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,04354454 0,11700052 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,04354454 0,11686399 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,04354454 0,11672779 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,04354454 0,1165919 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04354454 0,11645633 ! prophase GO:0051324 11 8 0,000 0,04354454 0,11632107 ! S phase GO:0051320 8 8 0,000 0,04354454 0,11618613 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,04354454 0,1160515 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,04354454 0,11591718 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,04354454 0,11578317 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,04354454 0,11564947 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,04354454 0,11551608 ! hormone catabolic process GO:0042447 13 8 0,000 0,04354454 0,115383 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,04354454 0,11525022 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,04354454 0,11511775 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,04354454 0,11498558 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,04354454 0,11485372 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,04354454 0,11472216 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,04354454 0,11459089 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,04354454 0,11445993 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04354454 0,11432927 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,04354454 0,11419891 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,04354454 0,11406884 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,04354454 0,11393907 ! lamellipodium assembly GO:0030032 9 8 0,000 0,04354454 0,11380959 ! regulation of embryonic development GO:0045995 16 8 0,000 0,04354454 0,11368041 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04354454 0,11355152 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,04354454 0,11342292 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,04354454 0,11329462 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,04380495 0,11384339 ! extracellular matrix organization GO:0030198 103 61 1,000 0,0451298 0,11715412 ! meiosis GO:0007126 96 61 1,000 0,0451298 0,11702204 GO:0051327|M phase of meiotic cell cycle, ! fatty acid biosynthetic process GO:0006633 92 61 1,000 0,0451298 0,11689026 ! amine catabolic process GO:0009310 90 62 1,000 0,04646939 0,12022452 ! meiotic cell cycle GO:0051321 97 62 1,000 0,04646939 0,12008944 ! organelle localization GO:0051640 96 62 1,000 0,04646939 0,11995466 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,04782351 0,12331175 GO:0090046|regulation of transcription regulator activity, ! regulation of lipase activity GO:0060191 109 63 1,000 0,04782351 0,12317366 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,04885392 0,12568683 ! regulation of developmental growth GO:0048638 13 9 0,000 0,04885392 0,1255464 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,04885392 0,12540628 ! telencephalon cell migration GO:0022029 16 9 0,000 0,04885392 0,12526647 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,04885392 0,12512698 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,04885392 0,12498779 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,04885392 0,12484892 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,04885392 0,12471035 GO:0010469|regulation of receptor activity, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,04885392 0,12457209 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,04885392 0,12443414 ! elastic fiber assembly GO:0048251 13 9 0,000 0,04885392 0,12429649 ! social behavior GO:0035176 14 9 0,000 0,04885392 0,12415914 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,04885392 0,1240221 ! artery development GO:0060840 19 9 0,000 0,04885392 0,12388536 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,04885392 0,12374893 ! regulation of glycolysis GO:0006110 15 9 0,000 0,04885392 0,12361279 ! response to pain GO:0048265 16 9 0,000 0,04885392 0,12347695 ! protein complex disassembly GO:0043241 17 9 0,000 0,04885392 0,12334141 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,04885392 0,12320617 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,04885392 0,12307122 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,04885392 0,12293657 ! lung alveolus development GO:0048286 17 9 0,000 0,04885392 0,12280221 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,04885392 0,12266815 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,04885392 0,12253438 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,04885392 0,1224009 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,04885392 0,12226771 ! ventral spinal cord development GO:0021517 11 9 0,000 0,04885392 0,12213481 ! protein targeting to ER GO:0045047 19 9 0,000 0,04885392 0,1220022 ! T cell selection GO:0045058 18 9 0,000 0,04885392 0,12186988 ! endoderm development GO:0007492 12 9 0,000 0,04885392 0,12173784 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,04885392 0,12160609 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,04885392 0,12147462 ! arginine catabolic process GO:0006527 10 9 0,000 0,04885392 0,12134344 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,04885392 0,12121254 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,04885392 0,12108192 GO:0010833|telomere maintenance via telomere lengthening, ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04885392 0,12095159 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,04885392 0,12082153 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,04885392 0,12069176 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,04885392 0,12056226 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04885392 0,12043304 ! mannose metabolic process GO:0006013 9 9 0,000 0,04885392 0,1203041 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,04885392 0,12017543 ! receptor clustering GO:0043113 15 9 0,000 0,04885392 0,12004704 ! epithelial cell development GO:0002064 10 9 0,000 0,04885392 0,11991892 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,04885392 0,11979107 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,04885392 0,1196635 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,04885392 0,1195362 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,04885392 0,11940917 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,04885392 0,1192824 ! motor axon guidance GO:0008045 14 9 0,000 0,04885392 0,11915591 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,04885392 0,11902969 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,04885392 0,11890373 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,04885392 0,11877804 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,04885392 0,11865261 ! blastoderm segmentation GO:0007350 11 9 0,000 0,04885392 0,11852745 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,04885392 0,11840256 ! DNA ligation GO:0006266 14 9 0,000 0,04885392 0,11827792 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,04885392 0,11815355 ! response to amine stimulus GO:0014075 13 9 0,000 0,04885392 0,11802944 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,04885392 0,11790559 ! erythrocyte development GO:0048821 11 9 0,000 0,04885392 0,117782 ! renal water homeostasis GO:0003091 14 9 0,000 0,04885392 0,11765867 ! postreplication repair GO:0006301 11 9 0,000 0,04885392 0,11753559 ! mRNA cleavage GO:0006379 13 9 0,000 0,04885392 0,11741277 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,04885392 0,11729021 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,04885392 0,11716791 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,04885392 0,11704586 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,04885392 0,11692406 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,04885392 0,11680252 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,04885392 0,11668123 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,04885392 0,11656019 ! acid secretion GO:0046717 14 9 0,000 0,04885392 0,1164394 ! musculoskeletal movement GO:0050881 11 9 0,000 0,04885392 0,11631887 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,04885392 0,11619858 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,04885392 0,11607854 ! purine base metabolic process GO:0006144 18 9 0,000 0,04885392 0,11595875 ! oocyte differentiation GO:0009994 12 9 0,000 0,04885392 0,1158392 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,04885392 0,1157199 ! spleen development GO:0048536 15 9 0,000 0,04885392 0,11560085 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,04885392 0,11548204 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,04885392 0,11536348 ! detection of calcium ion GO:0005513 13 9 0,000 0,04885392 0,11524515 ! blastocyst formation GO:0001825 12 9 0,000 0,04885392 0,11512708 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,04885392 0,11500924 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,04885392 0,11489164 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,04885392 0,11477429 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04885392 0,11465717 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,04885392 0,11454029 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,04885392 0,11442365 ! prepulse inhibition GO:0060134 14 9 0,000 0,04885392 0,11430725 ! embryonic placenta development GO:0001892 12 9 0,000 0,04885392 0,11419108 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,04885392 0,11407515 ! insulin secretion GO:0030073 17 9 0,000 0,04885392 0,11395946 ! sequestering of metal ion GO:0051238 11 9 0,000 0,04885392 0,113844 ! response to nicotine GO:0035094 16 9 0,000 0,04885392 0,11372877 ! establishment of cell polarity GO:0030010 12 9 0,000 0,04885392 0,11361378 ! nucleus localization GO:0051647 15 9 0,000 0,04885392 0,11349902 ! regulation of synapse organization GO:0050807 12 9 0,000 0,04885392 0,11338449 ! regulation of caspase activity GO:0043281 97 65 1,000 0,05057457 0,11725958 ! protein oligomerization GO:0051259 100 65 1,000 0,05057457 0,11714149 ! axon guidance GO:0007411 99 66 1,000 0,05197111 0,12025508 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,0533814 0,12339419 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,05413414 0,12500855 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,05413414 0,12488317 ! neuron fate specification GO:0048665 11 10 0,000 0,05413414 0,12475803 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,05413414 0,12463315 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,05413414 0,12450852 ! thyroid gland development GO:0030878 19 10 0,000 0,05413414 0,12438413 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,05413414 0,12426 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,05413414 0,12413611 ! synapsis GO:0007129 13 10 0,000 0,05413414 0,12401247 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,05413414 0,12388907 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,05413414 0,12376592 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,05413414 0,12364302 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,05413414 0,12352035 ! sulfate transport GO:0008272 12 10 0,000 0,05413414 0,12339793 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,05413414 0,12327576 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,05413414 0,12315382 ! androgen metabolic process GO:0008209 13 10 0,000 0,05413414 0,12303213 ! phospholipid efflux GO:0033700 16 10 0,000 0,05413414 0,12291068 ! hippocampus development GO:0021766 19 10 0,000 0,05413414 0,12278946 ! blood vessel remodeling GO:0001974 21 10 0,000 0,05413414 0,12266849 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,05413414 0,12254775 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,05413414 0,12242725 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,05413414 0,12230699 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,05413414 0,12218696 ! pathogenesis GO:0009405 13 10 0,000 0,05413414 0,12206717 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,05413414 0,12194762 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05413414 0,12182829 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,05413414 0,1217092 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,05413414 0,12159035 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,05413414 0,12147172 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,05413414 0,12135333 ! melanocyte differentiation GO:0030318 15 10 0,000 0,05413414 0,12123517 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,05413414 0,12111723 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,05413414 0,12099953 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05413414 0,12088205 ! response to X-ray GO:0010165 16 10 0,000 0,05413414 0,12076481 ! B cell proliferation GO:0042100 14 10 0,000 0,05413414 0,12064779 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,05413414 0,12053099 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,05413414 0,12041443 ! forebrain cell migration GO:0021885 17 10 0,000 0,05413414 0,12029808 ! lipid digestion GO:0044241 15 10 0,000 0,05413414 0,12018197 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,05413414 0,12006607 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,05413414 0,1199504 ! UV protection GO:0009650 14 10 0,000 0,05413414 0,11983495 ! entry into host cell GO:0030260 20 10 0,000 0,05413414 0,11971973 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,05413414 0,11960472 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,05413414 0,11948994 ! negative regulation of ossification GO:0030279 19 10 0,000 0,05413414 0,11937537 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,05413414 0,11926103 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,05413414 0,11914691 ! regulation of bone resorption GO:0045124 24 10 0,000 0,05413414 0,119033 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,05413414 0,11891931 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,05413414 0,11880584 ! regulation of organ growth GO:0046620 11 10 0,000 0,05413414 0,11869258 ! response to dsRNA GO:0043331 18 10 0,000 0,05413414 0,11857954 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,05413414 0,11846671 ! embryonic axis specification GO:0000578 12 10 0,000 0,05413414 0,1183541 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,05413414 0,11824171 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,05413414 0,11812952 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,05413414 0,11801755 ! cranial nerve development GO:0021545 12 10 0,000 0,05413414 0,11790579 ! fucose catabolic process GO:0019317 16 10 0,000 0,05413414 0,11779424 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,05413414 0,11768291 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,05413414 0,11757178 ! protein sumoylation GO:0016925 12 10 0,000 0,05413414 0,11746086 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,05413414 0,11735016 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05413414 0,11723966 ! zymogen activation GO:0031638 14 10 0,000 0,05413414 0,11712937 ! salivary gland development GO:0007431 22 10 0,000 0,05413414 0,11701928 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05413414 0,1169094 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,05413414 0,11679973 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,05413414 0,11669027 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,05413414 0,11658101 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,05413414 0,11647195 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,05413414 0,1163631 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05413414 0,11625445 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,05413414 0,116146 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,05413414 0,11603776 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,05413414 0,11592972 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,05413414 0,11582188 ! detection of bacterium GO:0016045 10 10 0,000 0,05413414 0,11571423 ! embryonic gut development GO:0048566 11 10 0,000 0,05413414 0,11560679 ! activation of innate immune response GO:0002218 10 10 0,000 0,05413414 0,11549955 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,05413414 0,11539251 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,05413414 0,11528566 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,05413414 0,11517902 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,05413414 0,11507257 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,05413414 0,11496631 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,05413414 0,11486025 ! rhythmic process GO:0048511 105 68 1,000 0,05480525 0,11617702 ! response to drug GO:0042493 108 69 1,000 0,05624246 0,11911388 ! muscle cell differentiation GO:0042692 104 71 1,000 0,05915625 0,12516962 ! rRNA transcription GO:0009303 17 11 0,000 0,05938534 0,12553886 ! respiratory burst GO:0045730 14 11 0,000 0,05938534 0,12542358 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,05938534 0,12530851 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,05938534 0,12519366 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,05938534 0,12507901 ! virus-host interaction GO:0019048 17 11 0,000 0,05938534 0,12496457 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,05938534 0,12485035 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,05938534 0,12473633 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,05938534 0,12462252 ! RNA polyadenylation GO:0043631 19 11 0,000 0,05938534 0,12450891 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,05938534 0,12439552 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,05938534 0,12428233 ! mating GO:0007618 14 11 0,000 0,05938534 0,12416934 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,05938534 0,12405657 ! T cell proliferation GO:0042098 20 11 0,000 0,05938534 0,12394399 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,05938534 0,12383162 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,05938534 0,12371946 ! bone resorption GO:0045453 16 11 0,000 0,05938534 0,12360749 ! regulated secretory pathway GO:0045055 14 11 0,000 0,05938534 0,12349573 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,05938534 0,12338417 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,05938534 0,12327282 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,05938534 0,12316166 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,05938534 0,1230507 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,05938534 0,12293995 ! syncytium formation GO:0006949 15 11 0,000 0,05938534 0,12282939 ! plasma membrane organization GO:0007009 18 11 0,000 0,05938534 0,12271903 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,05938534 0,12260887 ! focal adhesion formation GO:0048041 24 11 0,000 0,05938534 0,1224989 ! mitotic spindle organization GO:0007052 15 11 0,000 0,05938534 0,12238914 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,05938534 0,12227957 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,05938534 0,1221702 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,05938534 0,12206102 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,05938534 0,12195203 ! adult heart development GO:0007512 11 11 0,000 0,05938534 0,12184325 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,05938534 0,12173465 ! temperature homeostasis GO:0001659 16 11 0,000 0,05938534 0,12162625 ! L-glutamate transport GO:0015813 16 11 0,000 0,05938534 0,12151804 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,05938534 0,12141003 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,05938534 0,1213022 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,05938534 0,12119457 ! stem cell development GO:0048864 29 11 0,000 0,05938534 0,12108713 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,05938534 0,12097988 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,05938534 0,12087281 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,05938534 0,12076594 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,05938534 0,12065926 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,05938534 0,12055276 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,05938534 0,12044645 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,05938534 0,12034033 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,05938534 0,1202344 ! ribosome assembly GO:0042255 13 11 0,000 0,05938534 0,12012865 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,05938534 0,12002309 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,05938534 0,11991772 ! chromatin silencing GO:0006342 19 11 0,000 0,05938534 0,11981253 ! nucleosome positioning GO:0016584 13 11 0,000 0,05938534 0,11970752 ! T cell homeostasis GO:0043029 20 11 0,000 0,05938534 0,1196027 ! regulation of isotype switching GO:0045191 19 11 0,000 0,05938534 0,11949806 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,05938534 0,1193936 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,05938534 0,11928933 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,05938534 0,11918523 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,05938534 0,11908132 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,05938534 0,11897759 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,05938534 0,11887405 ! male genitalia development GO:0030539 13 11 0,000 0,05938534 0,11877068 ! cholesterol efflux GO:0033344 19 11 0,000 0,05938534 0,11866749 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,05938534 0,11856448 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,05938534 0,11846165 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,05938534 0,11835899 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,05938534 0,11825652 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,05938534 0,11815422 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,05938534 0,1180521 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,05938534 0,11795015 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,05938534 0,11784839 ! lysogeny GO:0030069 18 11 0,000 0,05938534 0,11774679 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,05938534 0,11764537 ! acrosome reaction GO:0007340 13 11 0,000 0,05938534 0,11754413 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,05938534 0,11744306 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,06063245 0,11980638 ! response to hypoxia GO:0001666 132 72 1,000 0,06063245 0,11970354 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,06063245 0,11960088 ! regulation of blood pressure GO:0008217 107 73 1,000 0,06212126 0,12243265 ! response to oxygen levels GO:0070482 137 74 1,000 0,06362252 0,12528408 ! protein import into nucleus GO:0006606 118 74 1,000 0,06362252 0,12517691 ! lactation GO:0007595 20 12 0,000 0,06460769 0,12700656 ! reproductive cellular process GO:0048610 14 12 0,000 0,06460769 0,1268981 ! tRNA modification GO:0006400 14 12 0,000 0,06460769 0,12678983 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,06460769 0,12668174 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,06460769 0,12657383 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,06460769 0,12646611 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,06460769 0,12635857 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,06460769 0,12625121 ! non-recombinational repair GO:0000726 19 12 0,000 0,06460769 0,12614404 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,06460769 0,12603705 ! peroxisomal transport GO:0043574 21 12 0,000 0,06460769 0,12593023 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,06460769 0,1258236 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,06460769 0,12571715 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,06460769 0,12561088 ! heart looping GO:0001947 15 12 0,000 0,06460769 0,12550479 ! palate development GO:0060021 15 12 0,000 0,06460769 0,12539888 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,06460769 0,12529315 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,06460769 0,1251876 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,06460769 0,12508222 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,06460769 0,12497702 ! arginine metabolic process GO:0006525 13 12 0,000 0,06460769 0,124872 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,06460769 0,12476715 ! methionine metabolic process GO:0006555 13 12 0,000 0,06460769 0,12466248 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,06460769 0,12455799 ! Golgi organization GO:0007030 18 12 0,000 0,06460769 0,12445367 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,06460769 0,12434952 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,06460769 0,12424555 ! monoamine transport GO:0015844 13 12 0,000 0,06460769 0,12414175 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06460769 0,12403813 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,06460769 0,12393468 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,06460769 0,1238314 ! L-amino acid transport GO:0015807 20 12 0,000 0,06460769 0,12372829 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,06460769 0,12362536 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,06460769 0,12352259 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,06460769 0,12342 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,06460769 0,12331757 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,06460769 0,12321532 ! cerebellum development GO:0021549 13 12 0,000 0,06460769 0,12311324 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,06460769 0,12301132 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,06460769 0,12290958 ! histone methylation GO:0016571 15 12 0,000 0,06460769 0,122808 ! autonomic nervous system development GO:0048483 23 12 0,000 0,06460769 0,12270659 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,06460769 0,12260534 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,06460769 0,12250427 ! response to gamma radiation GO:0010332 20 12 0,000 0,06460769 0,12240336 ! regulation of epidermis development GO:0045682 17 12 0,000 0,06460769 0,12230261 ! intestinal absorption GO:0050892 19 12 0,000 0,06460769 0,12220204 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,06460769 0,12210162 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,06460769 0,12200138 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,06460769 0,12190129 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,06460769 0,12180137 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,06460769 0,12170162 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,06460769 0,12160203 ! microspike assembly GO:0030035 23 12 0,000 0,06460769 0,1215026 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,06460769 0,12140333 ! response to cold GO:0009409 14 12 0,000 0,06460769 0,12130423 ! response to nutrient GO:0007584 104 75 1,000 0,06513604 0,12219649 ! nuclear import GO:0051170 121 75 1,000 0,06513604 0,1220969 ! amine biosynthetic process GO:0009309 97 76 1,000 0,06666164 0,12485487 ! regulation of DNA binding GO:0051101 119 77 1,000 0,06819915 0,12763063 ! gland development GO:0048732 148 77 1,000 0,06819915 0,12752686 ! protein ubiquitination GO:0016567 125 77 1,000 0,06819915 0,12742326 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,06819915 0,12731984 ! nitrogen compound catabolic process GO:0044270 114 78 1,000 0,06974838 0,13010647 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,06980133 0,13009973 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,06980133 0,12999439 ! cGMP metabolic process GO:0046068 16 13 0,000 0,06980133 0,12988922 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,06980133 0,12978421 ! water transport GO:0006833 17 13 0,000 0,06980133 0,12967938 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,06980133 0,12957471 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,06980133 0,12947022 ! lipid localization GO:0010876 24 13 0,000 0,06980133 0,12936589 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,06980133 0,12926173 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,06980133 0,12915774 ! organelle fusion GO:0048284 28 13 0,000 0,06980133 0,12905392 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,06980133 0,12895026 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,06980133 0,12884677 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,06980133 0,12874344 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,06980133 0,12864028 ! response to hexose stimulus GO:0009746 19 13 0,000 0,06980133 0,12853729 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,06980133 0,12843446 ! glutamate metabolic process GO:0006536 18 13 0,000 0,06980133 0,12833179 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,06980133 0,12822929 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,06980133 0,12812695 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,06980133 0,12802478 ! exocrine system development GO:0035272 27 13 0,000 0,06980133 0,12792277 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,06980133 0,12782092 ! bone mineralization GO:0030282 15 13 0,000 0,06980133 0,12771923 ! regulation of exocytosis GO:0017157 17 13 0,000 0,06980133 0,1276177 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,06980133 0,12751634 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,06980133 0,12741514 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,06980133 0,12731409 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,06980133 0,12721321 ! genitalia development GO:0048806 15 13 0,000 0,06980133 0,12711249 ! regulation of cellular pH GO:0030641 20 13 0,000 0,06980133 0,12701192 ! cellular pigmentation GO:0033059 24 13 0,000 0,06980133 0,12691152 ! tissue regeneration GO:0042246 21 13 0,000 0,06980133 0,12681127 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,06980133 0,12671118 ! cofactor transport GO:0051181 19 13 0,000 0,06980133 0,12661125 ! NADP metabolic process GO:0006739 18 13 0,000 0,06980133 0,12651148 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,06980133 0,12641187 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,06980133 0,12631241 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06980133 0,12621311 ! gas transport GO:0015669 18 13 0,000 0,06980133 0,12611396 ! regulation of RNA stability GO:0043487 28 13 0,000 0,06980133 0,12601497 ! heme biosynthetic process GO:0006783 20 13 0,000 0,06980133 0,12591613 ! regulation of axon extension GO:0030516 23 13 0,000 0,06980133 0,12581745 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,06980133 0,12571893 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,06980133 0,12562056 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,06980133 0,12552234 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,06980133 0,12542427 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,06980133 0,12532636 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,06980133 0,1252286 ! protein localization in nucleus GO:0034504 133 80 1,000 0,07288133 0,13065243 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,07446471 0,13338694 ! vitamin metabolic process GO:0006766 103 81 1,000 0,07446471 0,13328313 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,07496644 0,13407684 ! superoxide anion generation GO:0042554 18 14 0,000 0,07496644 0,13397266 ! neuron maturation GO:0042551 21 14 0,000 0,07496644 0,13386865 ! regulation of S phase GO:0033261 18 14 0,000 0,07496644 0,13376479 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,07496644 0,1336611 ! myotube differentiation GO:0014902 21 14 0,000 0,07496644 0,13355757 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,07496644 0,13345419 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,07496644 0,13335098 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,07496644 0,13324793 ! inositol metabolic process GO:0006020 20 14 0,000 0,07496644 0,13314503 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,07496644 0,1330423 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,07496644 0,13293972 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,07496644 0,1328373 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,07496644 0,13273504 ! gene silencing by RNA GO:0031047 20 14 0,000 0,07496644 0,13263294 ! response to cAMP GO:0051591 19 14 0,000 0,07496644 0,13253099 ! limbic system development GO:0021761 25 14 0,000 0,07496644 0,1324292 ! startle response GO:0001964 21 14 0,000 0,07496644 0,13232757 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,07496644 0,13222609 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,07496644 0,13212477 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,07496644 0,1320236 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,07496644 0,13192259 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,07496644 0,13182173 ! glycine metabolic process GO:0006544 22 14 0,000 0,07496644 0,13172102 ! pituitary gland development GO:0021983 23 14 0,000 0,07496644 0,13162047 ! cellular response to starvation GO:0009267 21 14 0,000 0,07496644 0,13152008 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,07496644 0,13141983 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,07496644 0,13131974 ! regulation of heart rate GO:0002027 23 14 0,000 0,07496644 0,1312198 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,07496644 0,13112001 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,07496644 0,13102038 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,07496644 0,13092089 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,07496644 0,13082156 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,07496644 0,13072238 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,07496644 0,13062335 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,07496644 0,13052447 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! axon cargo transport GO:0008088 27 14 0,000 0,07496644 0,13042573 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,07496644 0,13032715 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,07496644 0,13022871 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,07496644 0,13013043 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,07496644 0,13003229 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07496644 0,1299343 ! mRNA splice site selection GO:0006376 26 14 0,000 0,07496644 0,12983646 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,07496644 0,12973876 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,07496644 0,12964122 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,07496644 0,12954382 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,07496644 0,12944656 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,07496644 0,12934945 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,07496644 0,12925249 ! muscle maintenance GO:0046716 19 14 0,000 0,07496644 0,12915567 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,07496644 0,129059 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,07496644 0,12896247 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,07496644 0,12886608 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,07496644 0,12876984 ! cell killing GO:0001906 20 14 0,000 0,07496644 0,12867375 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,07496644 0,12857779 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,07496644 0,12848198 ! cilium assembly GO:0042384 20 14 0,000 0,07496644 0,12838631 ! peptide hormone secretion GO:0030072 23 14 0,000 0,07496644 0,12829079 ! ossification GO:0001503 134 82 1,000 0,07605912 0,13006393 GO:0060348|bone development, ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,07766441 0,13271036 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,07766441 0,13261184 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,0792804 0,13527072 ! positive regulation of cell size GO:0045793 20 15 0,000 0,08010316 0,13657322 ! metencephalon development GO:0022037 19 15 0,000 0,08010316 0,13647206 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,08010316 0,13637104 ! skin development GO:0043588 25 15 0,000 0,08010316 0,13627018 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,08010316 0,13616946 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,08010316 0,13606889 ! lipid phosphorylation GO:0046834 23 15 0,000 0,08010316 0,13596847 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,08010316 0,1358682 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,08010316 0,13576808 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,08010316 0,1356681 ! bile acid metabolic process GO:0008206 22 15 0,000 0,08010316 0,13556827 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,08010316 0,13546859 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,08010316 0,13536905 ! adult walking behavior GO:0007628 25 15 0,000 0,08010316 0,13526966 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,08010316 0,13517042 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,08010316 0,13507132 ! centrosome cycle GO:0007098 16 15 0,000 0,08010316 0,13497237 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,08010316 0,13487356 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,08010316 0,13477489 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,08010316 0,13467637 ! cerebral cortex development GO:0021987 29 15 0,000 0,08010316 0,134578 ! response to osmotic stress GO:0006970 22 15 0,000 0,08010316 0,13447977 ! vesicle coating GO:0006901 25 15 0,000 0,08010316 0,13438168 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,08010316 0,13428373 ! DNA integration GO:0015074 22 15 0,000 0,08010316 0,13418593 ! peptide secretion GO:0002790 27 15 0,000 0,08010316 0,13408827 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,08010316 0,13399075 ! regulation of vasodilation GO:0042312 24 15 0,000 0,08010316 0,13389337 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,08010316 0,13379614 ! neuron recognition GO:0008038 22 15 0,000 0,08010316 0,13369904 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,08010316 0,13360209 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,08010316 0,13350527 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,08010316 0,1334086 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,08010316 0,13331207 ! biomineral formation GO:0031214 18 15 0,000 0,08010316 0,13321568 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,08010316 0,13311942 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,08010316 0,13302331 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,08010316 0,13292733 ! dopamine metabolic process GO:0042417 30 15 0,000 0,08010316 0,13283149 ! organic cation transport GO:0015695 19 15 0,000 0,08010316 0,13273579 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,08010316 0,13264023 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,08010316 0,1325448 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,08010316 0,13244952 ! defense response to virus GO:0051607 27 15 0,000 0,08010316 0,13235437 ! peptide hormone processing GO:0016486 19 15 0,000 0,08010316 0,13225935 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,08010316 0,13216448 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,08090693 0,13339495 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 1,000 0,08419096 0,13871004 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,08419096 0,13861075 ! protein secretion GO:0009306 27 16 0,000 0,08521165 0,14019085 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,08521165 0,14009064 ! hormone secretion GO:0046879 25 16 0,000 0,08521165 0,13999058 ! bone remodeling GO:0046849 24 16 0,000 0,08521165 0,13989065 ! endothelial cell migration GO:0043542 22 16 0,000 0,08521165 0,13979087 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,08521165 0,13969124 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08521165 0,13959174 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,08521165 0,13949239 ! glial cell development GO:0021782 24 16 0,000 0,08521165 0,13939318 ! patterning of blood vessels GO:0001569 24 16 0,000 0,08521165 0,1392941 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,08521165 0,13919517 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,08521165 0,13909638 ! protein polyubiquitination GO:0000209 26 16 0,000 0,08521165 0,13899773 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,08521165 0,13889922 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,08521165 0,13880085 GO:0030968|endoplasmic reticulum unfolded protein response, ! fructose metabolic process GO:0006000 20 16 0,000 0,08521165 0,13870262 ! regulation of protein binding GO:0043393 27 16 0,000 0,08521165 0,13860453 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,08521165 0,13850658 ! protein export from nucleus GO:0006611 24 16 0,000 0,08521165 0,13840876 ! negative regulation of immune response GO:0050777 28 16 0,000 0,08521165 0,13831108 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,08521165 0,13821354 ! DNA replication initiation GO:0006270 25 16 0,000 0,08521165 0,13811614 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,08521165 0,13801888 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,08521165 0,13792175 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,08521165 0,13782476 ! diencephalon development GO:0021536 25 16 0,000 0,08521165 0,1377279 ! oogenesis GO:0048477 23 16 0,000 0,08521165 0,13763118 ! neural crest cell migration GO:0001755 24 16 0,000 0,08521165 0,1375346 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,08521165 0,13743815 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,08521165 0,13734184 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,08521165 0,13724566 ! steroid catabolic process GO:0006706 22 16 0,000 0,08521165 0,13714962 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,08521165 0,13705371 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,08521165 0,13695794 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,08521165 0,13686229 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,08521165 0,13676679 ! sperm-egg recognition GO:0035036 16 16 0,000 0,08521165 0,13667141 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,08521165 0,13657617 ! nerve development GO:0021675 18 16 0,000 0,08521165 0,13648106 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,08521165 0,13638609 ! negative regulation of translation GO:0017148 22 16 0,000 0,08521165 0,13629124 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 1,000 0,08584814 0,13721384 ! carboxylic acid catabolic process GO:0046395 122 88 1,000 0,08584814 0,13711855 GO:0016054|organic acid catabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 1,000 0,0875152 0,13968422 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,089192 0,14226186 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,09029207 0,14391667 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,09029207 0,143817 ! negative regulation of defense response GO:0031348 19 17 0,000 0,09029207 0,14371748 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,09029207 0,14361809 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,09029207 0,14351883 ! glycerol metabolic process GO:0006071 20 17 0,000 0,09029207 0,14341972 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,09029207 0,14332074 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,09029207 0,1432219 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,09029207 0,14312319 ! signal complex assembly GO:0007172 29 17 0,000 0,09029207 0,14302462 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,09029207 0,14292619 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,09029207 0,14282789 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,09029207 0,14272973 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,09029207 0,1426317 ! memory GO:0007613 25 17 0,000 0,09029207 0,1425338 ! keratinization GO:0031424 17 17 0,000 0,09029207 0,14243604 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,09029207 0,14233842 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,09029207 0,14224093 ! retinoid metabolic process GO:0001523 22 17 0,000 0,09029207 0,14214357 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,09029207 0,14204634 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,09029207 0,14194925 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,09029207 0,14185229 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,09029207 0,14175546 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,09029207 0,14165877 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,09029207 0,1415622 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,09029207 0,14146577 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,09029207 0,14136947 ! membrane budding GO:0006900 29 17 0,000 0,09029207 0,1412733 ! heme metabolic process GO:0042168 27 17 0,000 0,09029207 0,14117726 ! actin filament bundle formation GO:0051017 26 17 0,000 0,09029207 0,14108135 ! neuromuscular junction development GO:0007528 23 17 0,000 0,09029207 0,14098558 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,09029207 0,14088993 ! body fluid secretion GO:0007589 27 17 0,000 0,09029207 0,14079441 ! stem cell differentiation GO:0048863 36 17 0,000 0,09029207 0,14069902 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,09029207 0,14060376 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,09029207 0,14050863 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,09029207 0,14041363 ! sensory perception of pain GO:0019233 23 17 0,000 0,09029207 0,14031875 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,09029207 0,14022401 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,09029207 0,14012939 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,09029207 0,1400349 ! synaptogenesis GO:0007416 24 17 0,000 0,09029207 0,13994053 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,09029207 0,1398463 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,09029207 0,13975219 ! cell-cell junction organization GO:0045216 25 17 0,000 0,09029207 0,13965821 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,09029207 0,13956435 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,09029207 0,13947062 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,09029207 0,13937701 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,09029207 0,13928354 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,09029207 0,13919018 ! response to virus GO:0009615 122 91 1,000 0,09087838 0,14000019 ! cell fate commitment GO:0045165 141 92 1,000 0,09257419 0,14251715 ! sulfur metabolic process GO:0006790 118 92 1,000 0,09257419 0,14242183 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,09427926 0,14494806 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,09534455 0,14648796 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,09534455 0,14639017 ! positive regulation of translation GO:0045727 28 18 0,000 0,09534455 0,14629251 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,09534455 0,14619498 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,09534455 0,14609758 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,09534455 0,14600031 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,09534455 0,14590317 ! cAMP metabolic process GO:0046058 33 18 0,000 0,09534455 0,14580616 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,09534455 0,14570928 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,09534455 0,14561253 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,09534455 0,14551591 ! axis specification GO:0009798 26 18 0,000 0,09534455 0,14541941 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,09534455 0,14532304 GO:0050886|endocrine process, ! pancreas development GO:0031016 26 18 0,000 0,09534455 0,1452268 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,09534455 0,14513069 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,09534455 0,1450347 ! glutamine metabolic process GO:0006541 23 18 0,000 0,09534455 0,14493884 ! response to retinoic acid GO:0032526 25 18 0,000 0,09534455 0,14484311 ! pigmentation during development GO:0048066 31 18 0,000 0,09534455 0,14474751 ! central nervous system neuron development GO:0021954 30 18 0,000 0,09534455 0,14465203 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,09534455 0,14455667 ! fucose metabolic process GO:0006004 26 18 0,000 0,09534455 0,14446144 ! response to fungus GO:0009620 19 18 0,000 0,09534455 0,14436634 ! peptide cross-linking GO:0018149 31 18 0,000 0,09534455 0,14427136 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,09534455 0,14417651 ! heart process GO:0003015 27 18 0,000 0,09534455 0,14408178 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,09534455 0,14398718 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,09534455 0,1438927 ! visual learning GO:0008542 35 18 0,000 0,09534455 0,14379834 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,09534455 0,14370411 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,09534455 0,14361 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,09534455 0,14351601 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,09534455 0,14342215 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,09534455 0,14332841 ! vitamin transport GO:0051180 24 18 0,000 0,09534455 0,14323479 ! hormone transport GO:0009914 27 18 0,000 0,09534455 0,1431413 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,09534455 0,14304793 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,09534455 0,14295467 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,09534455 0,14286154 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,09534455 0,14276854 ! cell-cell recognition GO:0009988 20 18 0,000 0,09534455 0,14267565 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,09534455 0,14258288 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,09534455 0,14249023 ! regulation of glucose import GO:0046324 21 18 0,000 0,09534455 0,14239771 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,09534455 0,1423053 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,09534455 0,14221302 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,09534455 0,14212085 ! electron transport chain GO:0022900 123 94 1,000 0,09599345 0,14299542 ! regulation of binding GO:0051098 151 95 1,000 0,0977166 0,14546808 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,09944857 0,14795066 ! response to light stimulus GO:0009416 153 96 1,000 0,09944857 0,14785502 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,10036926 0,14912746 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,10036926 0,14903119 ! positive regulation of ossification GO:0045778 30 19 0,000 0,10036926 0,14893504 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,10036926 0,14883901 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,10036926 0,14874311 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,10036926 0,14864733 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,10036926 0,14855168 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,10036926 0,14845615 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,10036926 0,14836074 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,10036926 0,14826545 ! regeneration GO:0031099 32 19 0,000 0,10036926 0,14817029 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,10036926 0,14807525 ! response to alkaloid GO:0043279 32 19 0,000 0,10036926 0,14798033 ! sensory perception of taste GO:0050909 23 19 0,000 0,10036926 0,14788553 ! peroxisome organization GO:0007031 29 19 0,000 0,10036926 0,14779085 ! digestive system process GO:0022600 30 19 0,000 0,10036926 0,14769629 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,10036926 0,14760186 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,10036926 0,14750755 ! response to vitamin A GO:0033189 26 19 0,000 0,10036926 0,14741335 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,10036926 0,14731928 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,10036926 0,14722532 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,10036926 0,14713149 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,10036926 0,14703778 ! response to starvation GO:0042594 30 19 0,000 0,10036926 0,14694418 ! sex determination GO:0007530 29 19 0,000 0,10036926 0,14685071 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,10036926 0,14675735 ! plasma membrane fusion GO:0045026 23 19 0,000 0,10036926 0,14666411 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,10036926 0,14657099 ! cytolysis GO:0019835 20 19 0,000 0,10036926 0,14647799 ! renal system process GO:0003014 35 19 0,000 0,10036926 0,1463851 ! vasodilation GO:0042311 33 19 0,000 0,10036926 0,14629234 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,10036926 0,14619969 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,10036926 0,14610716 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,10036926 0,14601474 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,10036926 0,14592245 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,10036926 0,14583026 ! sarcomere organization GO:0045214 23 19 0,000 0,10036926 0,1457382 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,10036926 0,14564625 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,10036926 0,14555442 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,10036926 0,1454627 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,10036926 0,1453711 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,10036926 0,14527962 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,10036926 0,14518824 ! protein stabilization GO:0050821 26 19 0,000 0,10036926 0,14509699 ! protein amino acid glycosylation GO:0006486 134 97 1,000 0,10118921 0,14619045 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,10118921 0,14609868 ! extracellular structure organization GO:0043062 156 99 1,000 0,10469591 0,15106687 ! protein import GO:0017038 156 99 1,000 0,10469591 0,15097216 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,10469591 0,15087756 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,10536635 0,15174866 ! iron ion transport GO:0006826 37 20 0,000 0,10536635 0,1516537 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,10536635 0,15155886 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,10536635 0,15146413 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,10536635 0,15136953 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,10536635 0,15127504 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,10536635 0,15118067 ! spinal cord development GO:0021510 31 20 0,000 0,10536635 0,15108642 ! response to ethanol GO:0045471 37 20 0,000 0,10536635 0,15099228 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,10536635 0,15089827 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,10536635 0,15080437 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,10536635 0,15071058 ! chromosome condensation GO:0030261 31 20 0,000 0,10536635 0,15061691 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,10536635 0,15052336 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,10536635 0,15042993 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,10536635 0,15033661 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,10536635 0,15024341 ! pallium development GO:0021543 38 20 0,000 0,10536635 0,15015032 ! DNA modification GO:0006304 28 20 0,000 0,10536635 0,15005735 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,10536635 0,14996449 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,10536635 0,14987175 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,10536635 0,14977912 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,10536635 0,14968661 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,10536635 0,14959421 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,10536635 0,14950192 ! collagen catabolic process GO:0030574 25 20 0,000 0,10536635 0,14940975 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,10536635 0,14931769 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,10536635 0,14922575 ! alditol metabolic process GO:0019400 24 20 0,000 0,10536635 0,14913392 ! actin filament-based movement GO:0030048 34 20 0,000 0,10536635 0,1490422 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,10646167 0,15049899 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 1,000 0,10646167 0,15040654 ! protein localization in organelle GO:0033365 161 100 1,000 0,10646167 0,15031421 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,11033597 0,1556888 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,11033597 0,15559334 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,11033597 0,155498 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,11033597 0,15540278 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,11033597 0,15530767 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,11033597 0,15521268 GO:0009799|determination of symmetry, ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,11033597 0,15511781 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,11033597 0,15502305 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,11033597 0,15492841 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,11033597 0,15483388 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,11033597 0,15473947 ! vesicle docking GO:0048278 27 21 0,000 0,11033597 0,15464518 ! phototransduction GO:0007602 25 21 0,000 0,11033597 0,154551 ! dendrite development GO:0016358 35 21 0,000 0,11033597 0,15445693 ! visual behavior GO:0007632 39 21 0,000 0,11033597 0,15436298 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,11033597 0,15426914 ! ovarian follicle development GO:0001541 30 21 0,000 0,11033597 0,15417542 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,11033597 0,15408181 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,11033597 0,15398831 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,11033597 0,15389493 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,11033597 0,15380166 ! cell aging GO:0007569 32 21 0,000 0,11033597 0,1537085 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,11033597 0,15361546 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,11033597 0,15352253 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,11033597 0,15342971 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,11033597 0,153337 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,11033597 0,15324441 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,11033597 0,15315192 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,11033597 0,15305955 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,11033597 0,15296729 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,11033597 0,15287514 ! fatty acid transport GO:0015908 30 21 0,000 0,11033597 0,1527831 ! immunoglobulin production GO:0002377 33 21 0,000 0,11033597 0,15269118 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,11033597 0,15259936 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,11033597 0,15250765 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,11033597 0,15241606 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,11033597 0,15232457 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,11033597 0,1522332 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,11033597 0,15214193 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,11033597 0,15205077 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,11033597 0,15195972 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,11033597 0,15186878 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,11033597 0,15177795 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,11033597 0,15168723 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,11033597 0,15159662 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,11033597 0,15150611 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,11527827 0,1581981 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,11527827 0,15810377 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,11527827 0,15800954 ! viral genome replication GO:0019079 29 22 0,000 0,11527827 0,15791543 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,11527827 0,15782144 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,11527827 0,15772755 ! leukocyte adhesion GO:0007159 38 22 0,000 0,11527827 0,15763378 ! molting cycle process GO:0022404 40 22 0,000 0,11527827 0,15754012 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! glutamate signaling pathway GO:0007215 34 22 0,000 0,11527827 0,15744656 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,11527827 0,15735312 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,11527827 0,1572598 ! vasculogenesis GO:0001570 33 22 0,000 0,11527827 0,15716658 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,11527827 0,15707347 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,11527827 0,15698047 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,11527827 0,15688758 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,11527827 0,1567948 ! lysosome organization GO:0007040 37 22 0,000 0,11527827 0,15670214 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,11527827 0,15660958 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,11527827 0,15651713 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,11527827 0,15642479 ! regulation of behavior GO:0050795 38 22 0,000 0,11527827 0,15633256 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,11527827 0,15624043 ! membrane depolarization GO:0051899 35 22 0,000 0,11527827 0,15614842 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,11527827 0,15605651 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,11527827 0,15596471 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,11527827 0,15587302 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,11527827 0,15578144 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,11527827 0,15568997 ! blastocyst development GO:0001824 37 22 0,000 0,11527827 0,1555986 ! neural tube closure GO:0001843 33 22 0,000 0,11527827 0,15550734 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,11527827 0,15541619 ! protein tetramerization GO:0051262 39 22 0,000 0,11527827 0,15532514 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,12019339 0,16185292 ! neuron fate commitment GO:0048663 32 23 0,000 0,12019339 0,16175822 ! embryonic pattern specification GO:0009880 31 23 0,000 0,12019339 0,16166362 ! myelination GO:0042552 35 23 0,000 0,12019339 0,16156914 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,12019339 0,16147476 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,12019339 0,1613805 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,12019339 0,16128634 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,12019339 0,1611923 ! vesicle targeting GO:0006903 32 23 0,000 0,12019339 0,16109836 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,12019339 0,16100454 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,12019339 0,16091082 ! osteoblast differentiation GO:0001649 40 23 0,000 0,12019339 0,16081721 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,12019339 0,16072372 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,12019339 0,16063033 ! interaction with host GO:0051701 37 23 0,000 0,12019339 0,16053705 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,12019339 0,16044387 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,12019339 0,16035081 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,12019339 0,16025785 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,12019339 0,160165 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,12019339 0,16007226 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,12019339 0,15997963 ! cell fate determination GO:0001709 45 23 0,000 0,12019339 0,1598871 ! pentose metabolic process GO:0019321 31 23 0,000 0,12019339 0,15979468 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,12019339 0,15970236 ! spermatid development GO:0007286 33 23 0,000 0,12019339 0,15961016 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,12019339 0,15951806 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,12019339 0,15942606 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,12019339 0,15933417 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,12019339 0,15924239 ! telomere organization GO:0032200 32 23 0,000 0,12019339 0,15915072 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,12019339 0,15905914 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,12019339 0,15896768 ! regulation of amine transport GO:0051952 38 23 0,000 0,12019339 0,15887632 ! liver development GO:0001889 40 23 0,000 0,12019339 0,15878506 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,12508148 0,16514777 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,12508148 0,16505302 ! initiation of viral infection GO:0019059 42 24 0,000 0,12508148 0,16495838 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,12508148 0,16486384 ! superoxide metabolic process GO:0006801 32 24 0,000 0,12508148 0,16476942 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,12508148 0,16467511 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,12508148 0,1645809 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,12508148 0,1644868 ! fat cell differentiation GO:0045444 37 24 0,000 0,12508148 0,16439281 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,12508148 0,16429892 ! sperm motility GO:0030317 27 24 0,000 0,12508148 0,16420514 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,12508148 0,16411147 ! vacuole organization GO:0007033 39 24 0,000 0,12508148 0,16401791 ! receptor metabolic process GO:0043112 37 24 0,000 0,12508148 0,16392445 ! neural crest cell development GO:0014032 39 24 0,000 0,12508148 0,1638311 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,12508148 0,16373785 ! primary neural tube formation GO:0014020 35 24 0,000 0,12508148 0,16364472 ! negative regulation of cell development GO:0010721 56 24 0,000 0,12508148 0,16355168 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,12508148 0,16345876 ! base-excision repair GO:0006284 31 24 0,000 0,12508148 0,16336593 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,12508148 0,16327322 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,12508148 0,16318061 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,12508148 0,1630881 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,12508148 0,1629957 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,1299427 0,16923454 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,1299427 0,16913877 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,1299427 0,1690431 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,1299427 0,16894754 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,1299427 0,16885209 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,1299427 0,16875675 ! peptide transport GO:0015833 43 25 0,000 0,1299427 0,16866151 ! male gonad development GO:0008584 33 25 0,000 0,1299427 0,16856639 ! iron ion homeostasis GO:0055072 39 25 0,000 0,1299427 0,16847137 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,1299427 0,16837645 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,1299427 0,16828165 ! phospholipid transport GO:0015914 35 25 0,000 0,1299427 0,16818695 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,1299427 0,16809235 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,1299427 0,16799787 ! detection of light stimulus GO:0009583 30 25 0,000 0,1299427 0,16790349 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,1299427 0,16780921 ! leukocyte proliferation GO:0070661 39 25 0,000 0,1299427 0,16771504 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,1299427 0,16762098 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,13477718 0,17375982 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,13477718 0,17366247 ! translational initiation GO:0006413 43 26 0,000 0,13477718 0,17356524 ! regulation of pH GO:0006885 36 26 0,000 0,13477718 0,17346811 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,13477718 0,17337109 ! post-embryonic development GO:0009791 42 26 0,000 0,13477718 0,17327418 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,13477718 0,17317738 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,13477718 0,17308069 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,13477718 0,1729841 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,13477718 0,17288763 ! spermatid differentiation GO:0048515 36 26 0,000 0,13477718 0,17279126 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,13477718 0,17269499 ! regulation of coagulation GO:0050818 39 26 0,000 0,13477718 0,17259884 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,13958507 0,17865647 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,13958507 0,1785571 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,13958507 0,17845785 ! membrane docking GO:0022406 39 27 0,000 0,13958507 0,17835871 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,13958507 0,17825967 ! catechol metabolic process GO:0009712 43 27 0,000 0,13958507 0,17816075 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,13958507 0,17806194 ! acute-phase response GO:0006953 42 27 0,000 0,13958507 0,17796323 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,13958507 0,17786464 ! myofibril assembly GO:0030239 36 27 0,000 0,13958507 0,17776615 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,13958507 0,17766778 ! response to ionizing radiation GO:0010212 47 27 0,000 0,13958507 0,17756951 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,13958507 0,17747135 ! natural killer cell activation GO:0030101 35 27 0,000 0,13958507 0,1773733 ! lipid oxidation GO:0034440 38 27 0,000 0,13958507 0,17727536 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,13958507 0,17717752 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,13958507 0,1770798 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,13958507 0,17698218 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,13958507 0,17688467 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,13958507 0,17678726 ! gene silencing GO:0016458 41 27 0,000 0,13958507 0,17668997 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,14436653 0,18264192 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,14436653 0,18254151 ! phenol metabolic process GO:0018958 44 28 0,000 0,14436653 0,18244122 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,14436653 0,18234103 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,14436653 0,18224095 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,14436653 0,18214098 ! cell junction assembly GO:0034329 56 28 0,000 0,14436653 0,18204113 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,14436653 0,18194138 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,14436653 0,18184174 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,14436653 0,18174221 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,14436653 0,18164279 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,14436653 0,18154347 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,14436653 0,18144427 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,14436653 0,18134517 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,14436653 0,18124619 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,14436653 0,18114731 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,14436653 0,18104853 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,14436653 0,18094987 ! mesoderm formation GO:0001707 46 28 0,000 0,14436653 0,18085131 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,14436653 0,18075286 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,14436653 0,18065452 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,14436653 0,18055629 ! ensheathment of neurons GO:0007272 43 28 0,000 0,14436653 0,18045816 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,14436653 0,18036014 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,14436653 0,18026222 ! neural tube formation GO:0001841 41 28 0,000 0,14436653 0,18016441 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,14436653 0,18006671 ! placenta development GO:0001890 37 28 0,000 0,14436653 0,17996911 ! regulation of B cell activation GO:0050864 42 28 0,000 0,14436653 0,17987162 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,14912168 0,18569565 ! regulation of innate immune response GO:0045088 38 29 0,000 0,14912168 0,18559517 ! ovulation cycle process GO:0022602 41 29 0,000 0,14912168 0,18549479 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,14912168 0,18539452 ! protein targeting to membrane GO:0006612 53 29 0,000 0,14912168 0,18529436 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,14912168 0,18519431 ! mismatch repair GO:0006298 34 29 0,000 0,14912168 0,18509437 ! muscle cell development GO:0055001 38 29 0,000 0,14912168 0,18499453 ! formation of primary germ layer GO:0001704 48 29 0,000 0,14912168 0,18489481 ! telencephalon development GO:0021537 52 29 0,000 0,14912168 0,18479519 ! eye morphogenesis GO:0048592 51 29 0,000 0,14912168 0,18469567 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,14912168 0,18459627 ! tissue homeostasis GO:0001894 42 29 0,000 0,14912168 0,18449697 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,15385068 0,19024546 ! collagen metabolic process GO:0032963 40 30 0,000 0,15385068 0,19014323 ! organic anion transport GO:0015711 51 30 0,000 0,15385068 0,19004112 ! cholesterol transport GO:0030301 46 30 0,000 0,15385068 0,18993911 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,15385068 0,18983721 ! spliceosome assembly GO:0000245 49 30 0,000 0,15385068 0,18973542 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,15385068 0,18963374 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,15385068 0,18953217 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,15385068 0,18943071 ! ceramide metabolic process GO:0006672 43 30 0,000 0,15385068 0,18932935 ! ovulation cycle GO:0042698 43 30 0,000 0,15385068 0,18922811 ! hindbrain development GO:0030902 45 30 0,000 0,15385068 0,18912697 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,15385068 0,18902594 ! adult locomotory behavior GO:0008344 47 30 0,000 0,15385068 0,18892502 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,15385068 0,1888242 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,15385068 0,1887235 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,15385068 0,1886229 ! response to heat GO:0009408 41 30 0,000 0,15385068 0,18852241 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,15385068 0,18842202 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,15385068 0,18832175 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,15855366 0,19397523 ! negative regulation of secretion GO:0051048 49 31 0,000 0,15855366 0,1938721 ! glial cell differentiation GO:0010001 55 31 0,000 0,15855366 0,19376909 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,15855366 0,19366618 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,15855366 0,19356339 ! odontogenesis GO:0042476 50 31 0,000 0,15855366 0,1934607 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,15855366 0,19335813 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,15855366 0,19325566 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,15855366 0,1931533 ! metanephros development GO:0001656 58 31 0,000 0,15855366 0,19305104 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,15855366 0,1929489 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,15855366 0,19284687 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,15855366 0,19274494 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,15855366 0,19264312 ! RNA modification GO:0009451 40 31 0,000 0,15855366 0,19254141 ! regulation of muscle development GO:0048634 48 32 0,000 0,16323078 0,19811651 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,16323078 0,19801202 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,16323078 0,19790763 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,16323078 0,19780336 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,16323078 0,1976992 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,16323078 0,19759515 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,16323078 0,19749121 ! peripheral nervous system development GO:0007422 53 32 0,000 0,16323078 0,19738737 ! regulation of protein stability GO:0031647 48 32 0,000 0,16323078 0,19728365 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,16323078 0,19718003 ! cytokine production GO:0001816 44 32 0,000 0,16323078 0,19707653 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,16323078 0,19697313 ! vesicle localization GO:0051648 47 32 0,000 0,16323078 0,19686984 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,16788216 0,20237367 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,16788216 0,20226766 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,16788216 0,20216176 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,16788216 0,20205597 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,16788216 0,20195029 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,16788216 0,20184473 ! ear morphogenesis GO:0042471 42 33 0,000 0,16788216 0,20173927 ! actomyosin structure organization GO:0031032 43 33 0,000 0,16788216 0,20163392 ! cell junction organization GO:0034330 63 33 0,000 0,16788216 0,20152869 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,16788216 0,20142356 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,16788216 0,20131854 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,16788216 0,20121363 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,16788216 0,20110883 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,16788216 0,20100414 ! female gonad development GO:0008585 49 33 0,000 0,16788216 0,20089956 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,16788216 0,20079509 ! positive regulation of cell development GO:0010720 54 33 0,000 0,16788216 0,20069073 ! lipid homeostasis GO:0055088 55 33 0,000 0,16788216 0,20058647 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,16788216 0,20048233 ! regulation of proteolysis GO:0030162 50 33 0,000 0,16788216 0,20037829 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,16788216 0,20027436 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,16788216 0,20017053 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,16788216 0,20006682 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,17250795 0,20547296 ! mRNA catabolic process GO:0006402 48 34 0,000 0,17250795 0,20536661 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,17250795 0,20526036 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,17250795 0,20515423 ! feeding behavior GO:0007631 45 34 0,000 0,17250795 0,20504821 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,17250795 0,20494229 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,17250795 0,20483649 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,17250795 0,2047308 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,17250795 0,20462521 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,17250795 0,20451973 ! neuron migration GO:0001764 46 34 0,000 0,17250795 0,20441436 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,17250795 0,2043091 ! female gamete generation GO:0007292 43 34 0,000 0,17250795 0,20420395 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,17250795 0,20409891 ! polyol metabolic process GO:0019751 44 34 0,000 0,17250795 0,20399398 ! aerobic respiration GO:0009060 47 34 0,000 0,17250795 0,20388915 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,17250795 0,20378443 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,17250795 0,20367982 ! embryonic organ development GO:0048568 45 34 0,000 0,17250795 0,20357531 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,17250795 0,20347091 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,17710829 0,20878988 ! Notch signaling pathway GO:0007219 56 35 0,000 0,17710829 0,20868292 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,17710829 0,20857607 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,17710829 0,20846933 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,17710829 0,20836269 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,17710829 0,20825617 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,17710829 0,20814975 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,17710829 0,20804344 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,17710829 0,20793725 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,17710829 0,20783115 ! pigment metabolic process GO:0042440 61 35 0,000 0,17710829 0,20772517 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,17710829 0,2076193 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,18168332 0,21287398 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,18168332 0,21276559 ! negative regulation of binding GO:0051100 58 36 0,000 0,18168332 0,21265732 ! organic ether metabolic process GO:0018904 46 36 0,000 0,18168332 0,21254915 ! neural tube development GO:0021915 50 36 0,000 0,18168332 0,21244109 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,18168332 0,21233314 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,18168332 0,2122253 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,18168332 0,21211758 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,18623317 0,21731927 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,18623317 0,21720907 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,18623317 0,21709898 ! learning GO:0007612 67 37 0,000 0,18623317 0,216989 ! ion transmembrane transport GO:0034220 56 37 0,000 0,18623317 0,21687913 ! regulation of protein secretion GO:0050708 51 37 0,000 0,18623317 0,21676937 ! amino acid activation GO:0043038 52 37 0,000 0,18623317 0,21665973 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,19075798 0,22181161 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,19075798 0,22169952 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,19075798 0,22158755 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,19075798 0,2214757 ! phagocytosis GO:0006909 60 38 0,000 0,19075798 0,22136395 ! mesenchymal cell development GO:0014031 64 38 0,000 0,19075798 0,22125232 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,19075798 0,22114081 ! maintenance of location in cell GO:0051651 69 38 0,000 0,19075798 0,2210294 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,19525789 0,22612948 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,19525789 0,22601568 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,19525789 0,22590199 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,19525789 0,22578841 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,19525789 0,22567495 ! male sex differentiation GO:0046661 53 39 0,000 0,19525789 0,22556161 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,19525789 0,22544837 ! chromatin remodeling GO:0006338 68 39 0,000 0,19525789 0,22533525 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,19525789 0,22522224 ! JNK cascade GO:0007254 54 39 0,000 0,19525789 0,22510935 ! developmental growth GO:0048589 62 39 0,000 0,19525789 0,22499657 ! synapse organization GO:0050808 55 39 0,000 0,19525789 0,2248839 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,19973304 0,22992292 ! response to calcium ion GO:0051592 58 40 0,000 0,19973304 0,2298079 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,19973304 0,229693 ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,19973304 0,22957821 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,19973304 0,22946353 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,19973304 0,22934897 ! peptide metabolic process GO:0006518 56 40 0,000 0,19973304 0,22923453 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,19973304 0,2291202 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,19973304 0,22900598 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,19973304 0,22889188 ! double-strand break repair GO:0006302 67 40 0,000 0,19973304 0,22877789 ! B cell differentiation GO:0030183 62 40 0,000 0,19973304 0,22866401 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,19973304 0,22855025 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,20418356 0,23352669 ! glucose transport GO:0015758 52 41 0,000 0,20418356 0,23341063 ! endosome transport GO:0016197 71 41 0,000 0,20418356 0,23329467 ! striated muscle contraction GO:0006941 62 41 0,000 0,20418356 0,23317884 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,20418356 0,23306312 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,20418356 0,23294751 ! biopolymer methylation GO:0043414 62 41 0,000 0,20418356 0,23283202 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,20418356 0,23271664 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,20860958 0,2376434 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,20860958 0,23752575 ! cellular component disassembly GO:0022411 64 42 0,000 0,20860958 0,23740823 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,20860958 0,23729081 ! hexose transport GO:0008645 54 42 0,000 0,20860958 0,23717352 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,20860958 0,23705634 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,20860958 0,23693927 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,20860958 0,23682232 ! excretion GO:0007588 63 42 0,000 0,20860958 0,23670549 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,20860958 0,23658877 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,20860958 0,23647217 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,20860958 0,23635568 ! regulation of cell shape GO:0008360 78 42 0,000 0,20860958 0,2362393 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,21301123 0,24110523 ! neuromuscular process GO:0050905 79 43 0,000 0,21301123 0,24098664 ! activation of caspase activity GO:0006919 65 43 0,000 0,21301123 0,24086816 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,21301123 0,24074979 ! tRNA processing GO:0008033 49 43 0,000 0,21301123 0,24063155 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,21301123 0,24051342 ! vesicle organization GO:0016050 79 43 0,000 0,21301123 0,2403954 ! response to insulin stimulus GO:0032868 63 43 0,000 0,21301123 0,2402775 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,21301123 0,24015972 ! methylation GO:0032259 64 43 0,000 0,21301123 0,24004205 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,21738866 0,244855 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,21738866 0,24473515 ! glycolysis GO:0006096 53 44 0,000 0,21738866 0,24461541 ! regulation of action potential GO:0001508 71 44 0,000 0,21738866 0,2444958 ! regulation of ion transport GO:0043269 57 44 0,000 0,21738866 0,2443763 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,21738866 0,24425692 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,21738866 0,24413765 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,21738866 0,2440185 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,21738866 0,24389947 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,21738866 0,24378055 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,21738866 0,24366175 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,21738866 0,24354306 ! RNA catabolic process GO:0006401 64 45 0,000 0,22174198 0,2482992 ! positive regulation of defense response GO:0031349 59 45 0,000 0,22174198 0,24817837 ! regulation of translational initiation GO:0006446 64 45 0,000 0,22174198 0,24805766 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,22174198 0,24793707 ! cell recognition GO:0008037 58 45 0,000 0,22174198 0,2478166 ! cell maturation GO:0048469 60 45 0,000 0,22174198 0,24769624 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,22607134 0,25240975 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,22607134 0,25228728 ! cell redox homeostasis GO:0045454 63 46 0,000 0,22607134 0,25216493 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,22607134 0,2520427 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,22607134 0,25192058 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,23037686 0,25659408 ! viral infectious cycle GO:0019058 71 47 0,000 0,23037686 0,25646989 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,23037686 0,25634581 ! endocrine system development GO:0035270 83 47 0,000 0,23037686 0,25622185 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,23037686 0,25609801 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,23037686 0,25597429 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,23037686 0,25585069 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,23037686 0,25572721 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,23037686 0,25560385 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,23037686 0,25548061 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,23037686 0,25535749 ! chloride transport GO:0006821 67 48 0,000 0,23465868 0,2599783 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,23465868 0,25985313 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,23465868 0,25972808 ! response to temperature stimulus GO:0009266 62 48 0,000 0,23465868 0,25960315 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,23465868 0,25947835 ! gastrulation GO:0007369 73 48 0,000 0,23465868 0,25935366 ! heart morphogenesis GO:0003007 65 48 0,000 0,23465868 0,25922909 ! regulation of DNA replication GO:0006275 75 48 0,000 0,23465868 0,25910464 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,23465868 0,25898031 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,23465868 0,25885609 ! regulation of endocytosis GO:0030100 63 48 0,000 0,23465868 0,258732 ! nuclear export GO:0051168 69 48 0,000 0,23465868 0,25860803 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,23465868 0,25848418 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,23465868 0,25836044 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,23891691 0,26292292 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,23891691 0,26279718 ! sensory perception of smell GO:0007608 61 49 0,000 0,23891691 0,26267156 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,23891691 0,26254606 ! RNA elongation GO:0006354 62 49 0,000 0,23891691 0,26242068 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,23891691 0,26229542 ! germ cell development GO:0007281 68 49 0,000 0,23891691 0,26217028 ! maintenance of location GO:0051235 84 49 0,000 0,23891691 0,26204526 ! regulation of actin filament length GO:0030832 72 50 0,000 0,2431517 0,26656288 ! membrane fusion GO:0006944 80 50 0,000 0,2431517 0,26643588 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,2431517 0,26630901 ! lipid modification GO:0030258 73 50 0,000 0,2431517 0,26618225 ! positive regulation of growth GO:0045927 67 50 0,000 0,2431517 0,26605562 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,2431517 0,26592911 ! proton transport GO:0015992 75 50 0,000 0,2431517 0,26580272 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,2431517 0,26567644 ! positive regulation of secretion GO:0051047 71 51 0,000 0,24736317 0,27014971 ! hydrogen transport GO:0006818 77 51 0,000 0,24736317 0,27002149 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,24736317 0,2698934 ! adult behavior GO:0030534 80 51 0,000 0,24736317 0,26976543 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,24736317 0,26963758 ! transition metal ion transport GO:0000041 74 52 0,000 0,25155144 0,2740731 ! regulation of cellular component size GO:0032535 74 52 0,000 0,25155144 0,27394333 ! aging GO:0007568 79 52 0,000 0,25155144 0,27381368 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,25155144 0,27368416 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,25155144 0,27355476 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,25571665 0,27795288 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,25571665 0,27782158 ! kidney development GO:0001822 90 53 0,000 0,25571665 0,27769041 ! single fertilization GO:0007338 59 53 0,000 0,25571665 0,27755936 ! amino acid transport GO:0006865 84 54 0,000 0,25985891 0,2819224 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,25985891 0,28178948 ! glucose catabolic process GO:0006007 66 54 0,000 0,25985891 0,28165669 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,25985891 0,28152402 ! DNA catabolic process GO:0006308 67 54 0,000 0,25985891 0,28139147 ! detection of external stimulus GO:0009581 66 54 0,000 0,25985891 0,28125905 ! exocytosis GO:0006887 74 55 0,000 0,26397835 0,28558335 ! mesoderm development GO:0007498 76 55 0,000 0,26397835 0,28544909 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,2680751 0,28974283 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,2680751 0,28960674 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,27214929 0,29387012 ! carbohydrate transport GO:0008643 74 57 0,000 0,27214929 0,29373222 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,27214929 0,29359445 GO:0048609|reproductive process in a multicellular organism, ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,27214929 0,2934568 ! camera-type eye development GO:0043010 88 57 0,000 0,27214929 0,29331929 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,27214929 0,2931819 ! developmental maturation GO:0021700 75 57 0,000 0,27214929 0,29304465 ! gonad development GO:0008406 79 57 0,000 0,27214929 0,29290752 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,27620102 0,29712926 ! viral reproductive process GO:0022415 87 58 0,000 0,27620102 0,29699035 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,27620102 0,29685157 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,27620102 0,29671292 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,27620102 0,2965744 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,28023044 0,30076062 ! activation of MAPK activity GO:0000187 84 59 0,000 0,28023044 0,30062034 ! actin filament organization GO:0007015 95 59 0,000 0,28023044 0,30048019 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,28023044 0,30034017 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,28023044 0,30020028 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,28423765 0,3043513 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,28423765 0,30420968 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,28423765 0,30406818 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,28423765 0,30392682 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,28423765 0,30378559 ! regulation of heart contraction GO:0008016 91 60 0,000 0,28423765 0,30364449 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,28423765 0,30350353 ! fertilization GO:0009566 68 60 0,000 0,28423765 0,30336269 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,28822278 0,30747328 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,28822278 0,30733074 ! urogenital system development GO:0001655 101 61 0,000 0,28822278 0,30718832 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,28822278 0,30704604 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,28822278 0,30690389 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,28822278 0,30676187 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,28822278 0,30661998 ! neurotransmitter transport GO:0006836 81 62 0,000 0,29218595 0,31069241 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,29218595 0,31054884 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,29218595 0,3104054 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,29218595 0,31026209 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,29218595 0,31011891 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,29612728 0,31415717 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,29612728 0,31401233 ! viral reproduction GO:0016032 92 63 0,000 0,29612728 0,31386762 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,30004689 0,31787556 ! negative regulation of cell size GO:0045792 108 64 0,000 0,30004689 0,31772921 ! appendage morphogenesis GO:0035107 93 64 0,000 0,30004689 0,31758299 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,30004689 0,31743691 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,30004689 0,31729096 ! hexose catabolic process GO:0019320 82 64 0,000 0,30004689 0,31714515 ! adaptive immune response GO:0002250 94 64 0,000 0,30004689 0,31699947 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,30394489 0,32097027 ! appendage development GO:0048736 94 65 0,000 0,30394489 0,32082297 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,30394489 0,32067581 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,30394489 0,32052877 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,30394489 0,32038188 ! defense response to bacterium GO:0042742 73 65 0,000 0,30394489 0,32023511 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,30394489 0,32008849 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,30394489 0,31994199 ! activation of immune response GO:0002253 83 65 0,000 0,30394489 0,31979563 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,30782141 0,32372622 ! antigen processing and presentation GO:0019882 96 66 0,000 0,30782141 0,32357827 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,30782141 0,32343045 ! regulation of immune effector process GO:0002697 101 66 0,000 0,30782141 0,32328276 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,31167657 0,32718215 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,31167657 0,32703289 ! acute inflammatory response GO:0002526 92 68 0,000 0,31551047 0,33090473 ! learning or memory GO:0007611 123 68 0,000 0,31551047 0,33075391 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,31551047 0,33060322 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,31551047 0,33045267 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,31551047 0,33030226 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,31551047 0,33015199 ! inorganic anion transport GO:0015698 93 68 0,000 0,31551047 0,33000185 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,31932323 0,33383792 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,31932323 0,33368625 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,31932323 0,33353471 ! response to metal ion GO:0010038 103 70 0,000 0,32311497 0,33734201 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,32311497 0,33718895 ! humoral immune response GO:0006959 86 70 0,000 0,32311497 0,33703603 ! eye development GO:0001654 111 70 0,000 0,32311497 0,33688325 ! amine transport GO:0015837 101 70 0,000 0,32311497 0,3367306 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,32311497 0,3365781 ! regulation of catabolic process GO:0009894 106 70 0,000 0,32311497 0,33642573 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,32688581 0,34019791 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,32688581 0,34004404 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,32688581 0,33989031 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,32688581 0,33973672 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,32688581 0,33958328 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,32688581 0,33942996 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,33063586 0,34316899 ! negative regulation of transport GO:0051051 116 73 0,000 0,33436523 0,34688319 ! tube morphogenesis GO:0035239 118 73 0,000 0,33436523 0,34672679 ! mitochondrion organization GO:0007005 104 73 0,000 0,33436523 0,34657054 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,33436523 0,34641443 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,33436523 0,34625846 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,33807403 0,34994162 ! digestion GO:0007586 97 74 0,000 0,33807403 0,3497842 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,33807403 0,34962692 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,33807403 0,34946979 ! blood coagulation GO:0007596 116 75 0,000 0,34176239 0,35312376 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,34176239 0,35296519 ! negative regulation of growth GO:0045926 123 75 0,000 0,34176239 0,35280677 ! regulation of ligase activity GO:0051340 114 75 0,000 0,34176239 0,35264849 ! tRNA metabolic process GO:0006399 95 76 0,000 0,3454304 0,3562735 ! response to unfolded protein GO:0006986 99 76 0,000 0,3454304 0,35611381 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,3454304 0,35595426 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,34907818 0,35955208 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,34907818 0,35939114 ! sex differentiation GO:0007548 105 77 0,000 0,34907818 0,35923034 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,34907818 0,35906968 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,34907818 0,35890917 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,35270584 0,36247695 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,35631348 0,366021 ! cellular respiration GO:0045333 107 79 0,000 0,35631348 0,3658576 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,35631348 0,36569434 ! T cell activation GO:0042110 134 79 0,000 0,35631348 0,36553123 ! regulation of lyase activity GO:0051339 133 79 0,000 0,35631348 0,36536826 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,35631348 0,36520544 ! chromatin assembly GO:0031497 102 80 0,000 0,35990123 0,36871841 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,35990123 0,36855425 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,35990123 0,36839023 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,35990123 0,36822635 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,36346919 0,37171149 ! hemostasis GO:0007599 125 81 0,000 0,36346919 0,37154628 ! mRNA transport GO:0051028 121 81 0,000 0,36346919 0,37138123 ! response to protein stimulus GO:0051789 111 81 0,000 0,36346919 0,37121631 ! regulation of neurological system process GO:0031644 122 81 0,000 0,36346919 0,37105155 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,36346919 0,37088693 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 0,000 0,36701746 0,37434154 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,37054616 0,37777312 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of defense response GO:0031347 117 84 0,000 0,37405538 0,38118183 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,37405538 0,38101301 ! sterol metabolic process GO:0016125 120 84 0,000 0,37405538 0,38084435 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,37754525 0,38422746 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,37754525 0,38405753 ! rRNA metabolic process GO:0016072 107 85 0,000 0,37754525 0,38388774 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,37754525 0,3837181 ! regulation of membrane potential GO:0042391 128 85 0,000 0,37754525 0,38354862 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,37754525 0,38337928 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,38101585 0,38673277 ! cell cycle arrest GO:0007050 150 86 0,000 0,38101585 0,38656218 ! nucleosome organization GO:0034728 114 87 0,000 0,3844673 0,38989189 ! cellular defense response GO:0006968 102 87 0,000 0,3844673 0,38972005 ! female pregnancy GO:0007565 130 87 0,000 0,3844673 0,38954837 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,38789971 0,39285307 ! establishment of RNA localization GO:0051236 128 88 0,000 0,38789971 0,39268016 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,38789971 0,3925074 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,39131317 0,39578729 ! reproductive developmental process GO:0003006 127 89 0,000 0,39131317 0,39561331 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,39131317 0,39543949 ! regulation of T cell activation GO:0050863 128 89 0,000 0,39131317 0,39526583 ! leukocyte differentiation GO:0002521 143 90 0,000 0,39470779 0,39851972 ! hormone metabolic process GO:0042445 121 90 0,000 0,39470779 0,39834485 ! RNA localization GO:0006403 135 91 0,000 0,39808367 0,40157563 ! ATP metabolic process GO:0046034 137 91 0,000 0,39808367 0,40139958 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,40144092 0,40460741 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,40144092 0,40443018 ! positive regulation of immune response GO:0050778 121 92 0,000 0,40144092 0,40425311 ! DNA recombination GO:0006310 146 92 0,000 0,40144092 0,4040762 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,40477963 0,4072586 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,40477963 0,40708052 ! response to oxidative stress GO:0006979 141 94 0,000 0,40809991 0,4102403 ! carboxylic acid transport GO:0046942 147 95 0,000 0,41140186 0,41337889 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,41468558 0,41649644 ! in utero embryonic development GO:0001701 147 96 0,000 0,41468558 0,41631464 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,41468558 0,416133 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,41468558 0,41595152 ! protein maturation GO:0051604 129 96 0,000 0,41468558 0,4157702 ! calcium ion transport GO:0006816 167 99 0,000 0,42442834 0,42535302 ! regulation of translation GO:0006417 151 100 0,000 0,42764013 0,42838515 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,42764013 0,42819865 ! divalent metal ion transport GO:0070838 171 100 0,000 0,42764013 0,42801231 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,42764013 0,42782614 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,42764013 0,42764013