pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1132-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 6,000 1,396E-11 3,36E-08 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 4,000 1,857E-08 2,234E-05 ! regulation of epithelial cell proliferation GO:0050678 111 43 5,000 3,859E-08 3,095E-05 ! cell growth GO:0016049 84 45 4,000 1,777E-06 1,069E-03 ! positive regulation of protein ubiquitination GO:0031398 12 7 2,000 3,043E-06 1,464E-03 ! regulation of protein ubiquitination GO:0031396 25 16 2,000 4,726E-05 0,01895227 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 9,496E-05 0,03263826 ! peptidyl-serine modification GO:0018209 43 20 2,000 9,496E-05 0,02855847 ! inner ear receptor cell differentiation GO:0060113 37 20 2,000 9,496E-05 0,02538531 ! mechanoreceptor differentiation GO:0042490 40 22 2,000 1,274E-04 0,03066129 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 1,274E-04 0,0278739 ! meiotic chromosome segregation GO:0045132 7 5 1,000 1,977E-04 0,03963726 ! circadian behavior GO:0048512 13 5 1,000 1,977E-04 0,03658824 ! metallo-sulfur cluster assembly GO:0031163 5 5 1,000 1,977E-04 0,03397479 GO:0016226|iron-sulfur cluster assembly, ! benzene and derivative metabolic process GO:0042537 12 5 1,000 1,977E-04 0,0317098 ! microvillus organization GO:0032528 7 5 1,000 1,977E-04 0,02972794 GO:0030033|microvillus assembly, ! tryptophan metabolic process GO:0006568 9 5 1,000 1,977E-04 0,02797924 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,977E-04 0,02642484 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 2,378E-04 0,03011041 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 2,381E-04 0,02864471 ! sleep GO:0030431 13 6 1,000 2,957E-04 0,03387486 ! response to interferon-gamma GO:0034341 15 6 1,000 2,957E-04 0,0323351 ! cysteine metabolic process GO:0006534 10 6 1,000 2,957E-04 0,03092922 ! vascular smooth muscle contraction GO:0014829 13 6 1,000 2,957E-04 0,0296405 ! establishment of spindle localization GO:0051293 12 6 1,000 2,957E-04 0,02845488 GO:0051653|spindle localization, ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 2,957E-04 0,02736047 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,127E-04 0,03677751 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 4,127E-04 0,03546403 ! rhythmic behavior GO:0007622 15 7 1,000 4,127E-04 0,03424113 ! peptidyl-threonine modification GO:0018210 25 7 1,000 4,127E-04 0,03309976 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 4,472E-04 0,03470611 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 4,917E-04 0,03697331 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 5,487E-04 0,040003 ! UTP metabolic process GO:0046051 8 8 1,000 5,487E-04 0,03882644 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! ER overload response GO:0006983 12 8 1,000 5,487E-04 0,03771711 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 1,000 5,487E-04 0,03666941 ! NAD biosynthetic process GO:0009435 13 8 1,000 5,487E-04 0,03567835 ! CTP metabolic process GO:0046036 9 9 1,000 7,034E-04 0,04453377 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 1,000 7,034E-04 0,04339187 ! induction of an organ GO:0001759 14 9 1,000 7,034E-04 0,04230708 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 8,766E-04 0,05144246 ! L-serine metabolic process GO:0006563 18 10 1,000 8,766E-04 0,05021764 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 1,000 8,766E-04 0,04904978 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 1,000 8,766E-04 0,04793502 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 8,766E-04 0,04686979 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 1,000 8,766E-04 0,04585089 ! localization within membrane GO:0051668 20 10 1,000 8,766E-04 0,04487533 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 8,898E-04 0,04459935 ! epithelial cell differentiation GO:0030855 79 43 2,000 9,534E-04 0,04681263 ! JAK-STAT cascade GO:0007259 71 44 2,000 1,02E-03 0,0490726 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,068E-03 0,05039745 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,068E-03 0,04942826 ! indolalkylamine metabolic process GO:0006586 17 11 1,000 1,068E-03 0,04849566 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! vasoconstriction GO:0042310 18 11 1,000 1,068E-03 0,04759759 ! developmental induction GO:0031128 19 11 1,000 1,068E-03 0,04673218 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,161E-03 0,04989269 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,161E-03 0,04901738 ! cartilage condensation GO:0001502 20 12 1,000 1,278E-03 0,05302191 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,278E-03 0,05212324 ! asymmetric protein localization GO:0008105 20 12 1,000 1,278E-03 0,05125451 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 1,000 1,278E-03 0,05041428 ! histone acetylation GO:0016573 26 12 1,000 1,278E-03 0,04960114 ! gland morphogenesis GO:0022612 29 12 1,000 1,278E-03 0,04881382 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,278E-03 0,04805111 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 1,278E-03 0,04731186 ! biogenic amine catabolic process GO:0042402 23 12 1,000 1,278E-03 0,04659501 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,315E-03 0,04720505 ! inner ear development GO:0048839 79 50 2,000 1,48E-03 0,0523637 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,506E-03 0,05251808 ! serine family amino acid biosynthetic process GO:0009070 17 13 1,000 1,506E-03 0,05176782 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 1,000 1,506E-03 0,05103869 ! regulation of fatty acid oxidation GO:0046320 27 13 1,000 1,506E-03 0,05032982 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 1,567E-03 0,05165692 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,752E-03 0,05696358 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 1,752E-03 0,05620407 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 1,000 1,752E-03 0,05546454 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 1,752E-03 0,05474422 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 1,752E-03 0,05404237 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 1,000 2,016E-03 0,06138674 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 2,016E-03 0,06061941 ! regulation of intracellular transport GO:0032386 101 57 2,000 2,159E-03 0,06414474 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 2,297E-03 0,06739147 ! sulfur amino acid biosynthetic process GO:0000097 28 16 1,000 2,297E-03 0,06657953 ! intermediate filament-based process GO:0045103 32 16 1,000 2,297E-03 0,06578692 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 2,297E-03 0,06501295 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,297E-03 0,06425699 ! cellular amino acid derivative catabolic process GO:0042219 29 16 1,000 2,297E-03 0,0635184 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,595E-03 0,07096095 ! myoblast differentiation GO:0045445 45 17 1,000 2,595E-03 0,07016364 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 2,595E-03 0,06938404 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 1,000 2,595E-03 0,06862158 ! NAD metabolic process GO:0019674 29 17 1,000 2,595E-03 0,0678757 ! ear development GO:0043583 103 62 2,000 2,746E-03 0,07104597 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 2,911E-03 0,07451657 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 2,911E-03 0,07373219 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 2,911E-03 0,07296415 ! aromatic compound catabolic process GO:0019439 27 18 1,000 2,911E-03 0,07221194 ! G1 phase GO:0051318 40 19 1,000 3,244E-03 0,07965002 ! lung development GO:0030324 144 67 2,000 3,422E-03 0,08317312 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,594E-03 0,08647617 ! response to vitamin GO:0033273 31 20 1,000 3,594E-03 0,08561997 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 3,594E-03 0,08478055 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 3,594E-03 0,08395744 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 1,000 3,594E-03 0,08315016 ! respiratory tube development GO:0030323 150 70 2,000 3,873E-03 0,08873976 ! smooth muscle contraction GO:0006939 46 21 1,000 3,961E-03 0,08990497 ! response to cytokine stimulus GO:0034097 63 21 1,000 3,961E-03 0,08906473 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 4,192E-03 0,09338885 ! respiratory system development GO:0060541 153 72 2,000 4,192E-03 0,09253207 ! sulfur amino acid metabolic process GO:0000096 41 22 1,000 4,344E-03 0,09502053 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 4,344E-03 0,09416448 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 4,344E-03 0,09332373 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 4,344E-03 0,09249786 ! cell-matrix adhesion GO:0007160 163 75 2,000 4,7E-03 0,09919978 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 4,744E-03 0,09925426 ! gluconeogenesis GO:0006094 33 23 1,000 4,744E-03 0,09839862 ! protein amino acid O-linked glycosylation GO:0006493 42 23 1,000 4,744E-03 0,0975576 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 4,744E-03 0,09673084 GO:0010810|regulation of cell-substrate adhesion, ! pyrimidine nucleoside metabolic process GO:0006213 29 23 1,000 4,744E-03 0,09591798 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 5,16E-03 0,10346252 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 5,16E-03 0,10260746 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 5,16E-03 0,10176642 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 5,593E-03 0,10939579 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 5,593E-03 0,10851356 ! somitogenesis GO:0001756 43 25 1,000 5,593E-03 0,10764546 ! cell-substrate adhesion GO:0031589 171 81 2,000 5,824E-03 0,111219 ! pyruvate metabolic process GO:0006090 38 26 1,000 6,041E-03 0,1144442 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 6,041E-03 0,1135501 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 6,041E-03 0,11266987 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 6,041E-03 0,11180318 ! positive regulation of nuclear division GO:0051785 40 26 1,000 6,041E-03 0,11094972 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 6,041E-03 0,11010919 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 1,000 6,041E-03 0,1092813 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 6,505E-03 0,116801 ! protein amino acid acylation GO:0043543 55 27 1,000 6,505E-03 0,11593581 ! regulation of chromosome organization GO:0033044 42 27 1,000 6,505E-03 0,11508334 ! circadian rhythm GO:0007623 50 28 1,000 6,985E-03 0,12267217 ! negative regulation of protein modification process GO:0031400 60 28 1,000 6,985E-03 0,12178324 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 6,985E-03 0,1209071 ! vitamin biosynthetic process GO:0009110 39 28 1,000 6,985E-03 0,12004348 ! regulation of protein transport GO:0051223 154 87 2,000 7,097E-03 0,1210942 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 2,000 7,323E-03 0,12408291 ! nicotinamide metabolic process GO:0006769 52 30 1,000 7,992E-03 0,1344592 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor biosynthetic process GO:0051188 139 91 2,000 8,029E-03 0,13415149 ! alkaloid metabolic process GO:0009820 53 31 1,000 8,518E-03 0,14133645 ! serine family amino acid metabolic process GO:0009069 49 31 1,000 8,518E-03 0,14036839 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 9,03E-03 0,14780333 ! forebrain development GO:0030900 188 95 2,000 9,03E-03 0,14680466 ! spindle organization GO:0007051 46 32 1,000 9,059E-03 0,14628406 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 9,059E-03 0,14530884 ! hexose biosynthetic process GO:0019319 48 32 1,000 9,059E-03 0,14434653 ! regulation of protein localization GO:0032880 176 97 2,000 9,557E-03 0,15128068 ! cell fate specification GO:0001708 52 33 1,000 9,616E-03 0,15120875 ! leukocyte chemotaxis GO:0030595 50 33 1,000 9,616E-03 0,15022687 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 1,000 9,616E-03 0,14925767 ! interphase GO:0051325 213 98 2,000 9,827E-03 0,15156609 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01010165 0,15480622 GO:0060538|skeletal muscle organ development, ! xenobiotic metabolic process GO:0006805 51 34 1,000 0,01018673 0,15512203 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 1,000 0,01018673 0,15414642 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01077266 0,16199381 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01137314 0,16996139 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01137314 0,16891225 ! meiosis I GO:0007127 65 37 1,000 0,01198806 0,17695256 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 0,01198806 0,17587358 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01198806 0,17480768 ! tissue remodeling GO:0048771 76 37 1,000 0,01198806 0,17375463 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01198806 0,17271418 ! glucan metabolic process GO:0044042 62 38 1,000 0,01261726 0,18069717 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,01326061 0,18878712 ! segmentation GO:0035282 67 39 1,000 0,01326061 0,18767661 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,01326061 0,18657908 ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,01391797 0,19468971 ! cytokinesis GO:0000910 72 40 1,000 0,01391797 0,19356434 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,0145892 0,20173344 ! gliogenesis GO:0042063 88 41 1,000 0,0145892 0,20058067 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01527417 0,20880489 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 71 42 1,000 0,01527417 0,2076252 GO:0050880|regulation of blood vessel size, ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,01527417 0,20645877 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,01527417 0,20530537 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01597275 0,21350241 ! phagocytosis GO:0006909 90 43 1,000 0,01597275 0,21232284 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,01668479 0,22056931 ! leukocyte migration GO:0050900 68 45 1,000 0,01741018 0,22890101 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 1,000 0,01741018 0,22765698 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,01814876 0,23603203 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01890042 0,24448613 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01890042 0,24317872 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,01890042 0,24188522 ! protein homooligomerization GO:0051260 76 47 1,000 0,01890042 0,2406054 ! mitochondrial transport GO:0006839 82 48 1,000 0,01966503 0,24902136 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,01966503 0,24771759 ! regulation of ossification GO:0030278 117 50 1,000 0,02123255 0,26607042 ! histone modification GO:0016570 91 50 1,000 0,02123255 0,26469181 ! positive regulation of binding GO:0051099 78 51 1,000 0,02203521 0,2732821 ! cellular amino acid biosynthetic process GO:0008652 75 51 1,000 0,02203521 0,27188065 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02221402 0,27268845 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02221402 0,27130425 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02221402 0,26993402 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02221402 0,26857757 ! neuron fate determination GO:0048664 7 5 0,000 0,02221402 0,26723468 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02221402 0,26590516 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02221402 0,2645888 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02221402 0,2632854 ! polyol transport GO:0015791 12 5 0,000 0,02221402 0,26199479 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02221402 0,26071676 ! response to superoxide GO:0000303 10 5 0,000 0,02221402 0,25945115 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02221402 0,25819776 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02221402 0,25695643 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02221402 0,25572697 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02221402 0,25450922 ! female meiosis GO:0007143 7 5 0,000 0,02221402 0,25330302 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02221402 0,25210819 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02221402 0,25092458 ! cobalt ion transport GO:0006824 11 5 0,000 0,02221402 0,24975204 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02221402 0,2485904 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02221402 0,24743952 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02221402 0,24629925 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02221402 0,24516943 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02221402 0,24404994 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02221402 0,24294062 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02221402 0,24184134 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02221402 0,24075197 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02221402 0,23967236 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02221402 0,2386024 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02221402 0,23754194 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02221402 0,23649087 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02221402 0,23544906 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02221402 0,23441639 ! negative chemotaxis GO:0050919 14 5 0,000 0,02221402 0,23339274 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02221402 0,23237799 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02221402 0,23137202 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02221402 0,23037473 ! behavioral response to pain GO:0048266 9 5 0,000 0,02221402 0,22938599 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02221402 0,22840571 ! Notch receptor processing GO:0007220 8 5 0,000 0,02221402 0,22743377 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02221402 0,22647007 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02221402 0,2255145 ! micturition GO:0060073 9 5 0,000 0,02221402 0,22456696 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02221402 0,22362735 ! copulation GO:0007620 9 5 0,000 0,02221402 0,22269557 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02221402 0,22177152 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02221402 0,22085511 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02221402 0,21994624 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02221402 0,21904482 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02221402 0,21815076 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02221402 0,21726397 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02221402 0,21638436 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02221402 0,21551184 ! grooming behavior GO:0007625 6 5 0,000 0,02221402 0,21464633 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02221402 0,21378775 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02221402 0,212936 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02221402 0,21209102 ! response to protozoan GO:0001562 10 5 0,000 0,02221402 0,21125271 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02221402 0,21042101 ! lymph vessel development GO:0001945 10 5 0,000 0,02221402 0,20959583 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02221402 0,2087771 ! endochondral ossification GO:0001958 16 5 0,000 0,02221402 0,20796473 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02221402 0,20715867 ! parathyroid gland development GO:0060017 13 5 0,000 0,02221402 0,20635883 ! anagen GO:0042640 6 5 0,000 0,02221402 0,20556514 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02221402 0,20477753 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02221402 0,20399594 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02221402 0,20322029 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02221402 0,20245052 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02221402 0,20168655 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02221402 0,20092833 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02221402 0,20017579 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02221402 0,19942887 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02221402 0,1986875 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02221402 0,19795162 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02221402 0,19722117 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02221402 0,19649609 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02221402 0,19577632 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02221402 0,19506181 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02221402 0,1943525 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02221402 0,19364832 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02221402 0,19294923 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02221402 0,19225517 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02221402 0,19156608 ! histidine catabolic process GO:0006548 6 5 0,000 0,02221402 0,19088192 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02221402 0,19020262 ! valine metabolic process GO:0006573 10 5 0,000 0,02221402 0,18952814 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02221402 0,18885843 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02221402 0,18819344 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02221402 0,18753311 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02221402 0,1868774 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02221402 0,18622626 ! polyol catabolic process GO:0046174 7 5 0,000 0,02221402 0,18557964 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02221402 0,1849375 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02221402 0,18429978 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02221402 0,18366645 ! muscle cell migration GO:0014812 8 5 0,000 0,02221402 0,18303745 ! mitochondrial fission GO:0000266 8 5 0,000 0,02221402 0,18241275 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02221402 0,1817923 ! mRNA transcription GO:0009299 9 5 0,000 0,02221402 0,18117606 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02221402 0,18056398 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02221402 0,17995602 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02221402 0,17935214 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02221402 0,1787523 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02221402 0,17815646 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02221402 0,17756457 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02221402 0,17697661 ! response to food GO:0032094 6 5 0,000 0,02221402 0,17639253 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02221402 0,17581229 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02221402 0,17523586 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02221402 0,17466319 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02221402 0,17409426 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02221402 0,17352901 ! forebrain neuron development GO:0021884 13 5 0,000 0,02221402 0,17296743 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02221402 0,17240947 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02221402 0,1718551 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02221402 0,17130428 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02221402 0,17075699 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02221402 0,17021317 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02221402 0,16967281 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02221402 0,16913588 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02221402 0,16860232 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02221402 0,16807213 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02221402 0,16754526 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02221402 0,16702168 ! basic amino acid transport GO:0015802 11 5 0,000 0,02221402 0,16650136 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02221402 0,16598428 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02221402 0,16547039 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02221402 0,16495968 ! depyrimidination GO:0045008 10 5 0,000 0,02221402 0,16445211 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02221402 0,16394766 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02221402 0,16344629 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02221402 0,16294798 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02221402 0,16245269 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02221402 0,16196041 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02221402 0,16147111 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02221402 0,16098475 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02221402 0,16050131 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02221402 0,16002077 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02221402 0,15954309 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02221402 0,15906826 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02221402 0,15859625 ! response to arsenic GO:0046685 10 5 0,000 0,02221402 0,15812703 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02221402 0,15766058 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02221402 0,15719687 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02221402 0,15673588 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02221402 0,15627759 ! response to cadmium ion GO:0046686 7 5 0,000 0,02221402 0,15582197 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02221402 0,155369 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02221402 0,15491866 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02221402 0,15447092 ! decidualization GO:0046697 11 5 0,000 0,02221402 0,15402575 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02221402 0,15358315 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02221402 0,15314308 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02221402 0,15270553 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02221402 0,15227047 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02221402 0,15183789 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02221402 0,15140775 ! neural tube patterning GO:0021532 7 5 0,000 0,02221402 0,15098005 ! embryonic cleavage GO:0040016 6 5 0,000 0,02221402 0,15055475 ! peroxisome fission GO:0016559 5 5 0,000 0,02221402 0,15013184 ! histone demethylation GO:0016577 10 5 0,000 0,02221402 0,14971131 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02221402 0,14929312 ! mitotic recombination GO:0006312 9 5 0,000 0,02221402 0,14887726 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02221402 0,14846371 ! metaphase plate congression GO:0051310 7 5 0,000 0,02221402 0,14805246 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02221402 0,14764347 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02221402 0,14723674 ! enteric nervous system development GO:0048484 8 5 0,000 0,02221402 0,14683224 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02221402 0,14642996 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02221402 0,14602988 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02221402 0,14563198 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02221402 0,14523624 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02221402 0,14484265 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02221402 0,14445118 ! plasminogen activation GO:0031639 5 5 0,000 0,02221402 0,14406182 ! B cell homeostasis GO:0001782 13 5 0,000 0,02221402 0,14367456 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02221402 0,14328937 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02221402 0,14290625 ! metaphase GO:0051323 8 5 0,000 0,02221402 0,14252516 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02221402 0,14214611 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02221402 0,14176906 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02221402 0,14139401 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02221402 0,14102094 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02221402 0,14064983 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02221402 0,14028067 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02221402 0,13991345 ! response to redox state GO:0051775 5 5 0,000 0,02221402 0,13954814 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02221402 0,13918473 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02221402 0,13882321 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02221402 0,13846357 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02221402 0,13810578 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02221402 0,13774984 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02221402 0,13739572 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02221402 0,13704343 GO:0033015|tetrapyrrole catabolic process, ! striatum development GO:0021756 9 5 0,000 0,02221402 0,13669293 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02221402 0,13634423 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02221402 0,13599729 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02221402 0,13565212 ! glial cell migration GO:0008347 11 5 0,000 0,02221402 0,1353087 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02221402 0,13496701 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02221402 0,13462704 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02221402 0,13428879 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02221402 0,13395222 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02221402 0,13361734 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02221402 0,13328413 ! neuroprotection GO:0043526 6 5 0,000 0,02221402 0,13295258 ! neural plate development GO:0001840 8 5 0,000 0,02221402 0,13262267 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02221402 0,1322944 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02221402 0,13196774 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02221402 0,1316427 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02221402 0,13131925 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02221402 0,13099739 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02221402 0,13067711 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02221402 0,13035838 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02221402 0,13004121 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02221402 0,12972557 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02221402 0,12941147 ! spindle assembly GO:0051225 6 5 0,000 0,02221402 0,12909888 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02221402 0,1287878 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02221402 0,12847821 ! drug metabolic process GO:0017144 6 5 0,000 0,02221402 0,12817011 ! stem cell division GO:0017145 11 5 0,000 0,02221402 0,12786348 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02221402 0,12755832 ! organ regeneration GO:0031100 7 5 0,000 0,02221402 0,12725461 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02221402 0,12695234 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02221402 0,12665151 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02221402 0,1263521 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02285031 0,12966473 ! amino acid activation GO:0043038 92 52 1,000 0,02285031 0,12935963 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 1,000 0,02285031 0,12905597 ! response to UV GO:0009411 104 53 1,000 0,02367771 0,13341585 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,02451729 0,13782383 GO:0010863|positive regulation of phospholipase C activity, ! heterocycle catabolic process GO:0046700 85 54 1,000 0,02451729 0,13750257 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,02536893 0,141948 ! sulfur compound biosynthetic process GO:0044272 93 55 1,000 0,02536893 0,14161866 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,02536893 0,14129084 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,0262325 0,14576303 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,0262325 0,14542717 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02659769 0,14711276 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02659769 0,14677534 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02659769 0,14643947 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02659769 0,14610514 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02659769 0,14577232 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02659769 0,14544102 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02659769 0,14511122 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02659769 0,14478292 ! response to oxygen radical GO:0000305 11 6 0,000 0,02659769 0,14445609 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02659769 0,14413074 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02659769 0,14380685 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02659769 0,14348442 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02659769 0,14316342 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02659769 0,14284386 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02659769 0,14252572 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02659769 0,142209 ! forebrain regionalization GO:0021871 8 6 0,000 0,02659769 0,14189368 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02659769 0,14157976 ! male meiosis GO:0007140 7 6 0,000 0,02659769 0,14126722 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02659769 0,14095606 ! response to zinc ion GO:0010043 9 6 0,000 0,02659769 0,14064626 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02659769 0,14033783 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02659769 0,14003074 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02659769 0,139725 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02659769 0,13942059 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02659769 0,1391175 ! malate metabolic process GO:0006108 11 6 0,000 0,02659769 0,13881573 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02659769 0,13851526 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02659769 0,13821609 ! protein refolding GO:0042026 15 6 0,000 0,02659769 0,13791821 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02659769 0,13762161 ! opsonization GO:0008228 8 6 0,000 0,02659769 0,13732629 ! mating behavior GO:0007617 7 6 0,000 0,02659769 0,13703223 ! neuron remodeling GO:0016322 15 6 0,000 0,02659769 0,13673942 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02659769 0,13644787 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02659769 0,13615755 ! equilibrioception GO:0050957 14 6 0,000 0,02659769 0,13586847 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02659769 0,13558061 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02659769 0,13529397 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02659769 0,13500854 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02659769 0,13472431 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02659769 0,13444128 ! toxin metabolic process GO:0009404 11 6 0,000 0,02659769 0,13415943 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02659769 0,13387876 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02659769 0,13359927 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02659769 0,13332094 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02659769 0,13304376 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02659769 0,13276774 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02659769 0,13249286 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02659769 0,13221911 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02659769 0,13194649 ! thymic T cell selection GO:0045061 12 6 0,000 0,02659769 0,131675 ! protein lipoylation GO:0009249 10 6 0,000 0,02659769 0,13140462 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02659769 0,13113535 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02659769 0,13086718 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02659769 0,1306001 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02659769 0,13033411 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02659769 0,13006921 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02659769 0,12980537 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02659769 0,12954261 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02659769 0,12928091 ! hyperosmotic response GO:0006972 9 6 0,000 0,02659769 0,12902026 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02659769 0,12876066 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02659769 0,12850211 ! urea metabolic process GO:0019627 7 6 0,000 0,02659769 0,12824459 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02659769 0,1279881 ! neutrophil activation GO:0042119 8 6 0,000 0,02659769 0,12773263 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02659769 0,12747819 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02659769 0,12722475 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02659769 0,12697232 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02659769 0,12672089 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02659769 0,12647045 ! neuron apoptosis GO:0051402 9 6 0,000 0,02659769 0,126221 ! nucleoside salvage GO:0043174 9 6 0,000 0,02659769 0,12597254 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02659769 0,12572505 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02659769 0,12547853 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02659769 0,12523297 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02659769 0,12498838 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02659769 0,12474474 ! carnitine transport GO:0015879 10 6 0,000 0,02659769 0,12450204 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02659769 0,12426029 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02659769 0,12401948 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02659769 0,12377959 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02659769 0,12354064 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02659769 0,1233026 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02659769 0,12306548 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02659769 0,12282927 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02659769 0,12259396 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02659769 0,12235956 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02659769 0,12212605 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02659769 0,12189343 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02659769 0,12166169 ! neural nucleus development GO:0048857 14 6 0,000 0,02659769 0,12143083 ! response to UV-C GO:0010225 11 6 0,000 0,02659769 0,12120085 ! astrocyte development GO:0014002 15 6 0,000 0,02659769 0,12097174 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02659769 0,12074349 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02659769 0,1205161 ! interaction with symbiont GO:0051702 13 6 0,000 0,02659769 0,12028957 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02659769 0,12006388 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02659769 0,11983904 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02659769 0,11961505 ! response to copper ion GO:0046688 10 6 0,000 0,02659769 0,11939188 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02659769 0,11916955 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02659769 0,11894805 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02659769 0,11872736 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02659769 0,1185075 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02659769 0,11828845 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02659769 0,1180702 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02659769 0,11785276 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02659769 0,11763612 ! hair follicle maturation GO:0048820 7 6 0,000 0,02659769 0,11742027 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02659769 0,11720522 ! Schwann cell development GO:0014044 15 6 0,000 0,02659769 0,11699095 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02659769 0,11677746 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02659769 0,11656475 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02659769 0,11635282 ! subpallium development GO:0021544 10 6 0,000 0,02659769 0,11614165 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02659769 0,11593125 ! histone ubiquitination GO:0016574 8 6 0,000 0,02659769 0,11572161 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02659769 0,11551272 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02659769 0,11530459 ! G2 phase GO:0051319 16 6 0,000 0,02659769 0,11509721 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02659769 0,11489057 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02659769 0,11468468 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02659769 0,11447952 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02659769 0,11427509 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02659769 0,11407139 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02659769 0,11386842 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02659769 0,11366616 ! receptor internalization GO:0031623 10 6 0,000 0,02659769 0,11346463 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02659769 0,1132638 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02659769 0,11306369 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02659769 0,11286428 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02659769 0,11266558 ! protein deubiquitination GO:0016579 14 6 0,000 0,02659769 0,11246757 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02659769 0,11227026 ! protein destabilization GO:0031648 9 6 0,000 0,02659769 0,11207364 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02659769 0,11187771 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02659769 0,11168246 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02659769 0,11148789 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02659769 0,111294 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02659769 0,11110078 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02659769 0,11090823 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02659769 0,11071635 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02659769 0,11052513 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02659769 0,11033457 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02659769 0,11014466 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02659769 0,10995541 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02659769 0,10976681 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02659769 0,10957885 ! catecholamine transport GO:0051937 9 6 0,000 0,02659769 0,10939154 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02659769 0,10920486 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02659769 0,10901882 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02659769 0,10883342 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02659769 0,10864864 ! maternal placenta development GO:0001893 12 6 0,000 0,02659769 0,10846449 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02659769 0,10828096 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02659769 0,10809806 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02659769 0,10791577 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02659769 0,10773409 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02659769 0,10755302 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02659769 0,10737257 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02659769 0,10719271 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,02710788 0,10906616 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,02710788 0,10888408 ! muscle fiber development GO:0048747 112 57 1,000 0,02710788 0,10870261 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,02710788 0,10852174 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,02710788 0,10834147 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,02799495 0,11170126 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,02799495 0,11151632 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,02889359 0,11490576 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,02889359 0,11471615 ! establishment of organelle localization GO:0051656 109 59 1,000 0,02889359 0,11452716 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,02980368 0,11794024 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,02980368 0,11774657 ! tRNA transcription GO:0009304 14 7 0,000 0,03096186 0,12212168 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03096186 0,12192181 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03096186 0,12172259 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03096186 0,12152402 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03096186 0,1213261 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03096186 0,12112882 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03096186 0,12093218 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03096186 0,12073618 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03096186 0,12054082 ! prostate gland development GO:0030850 13 7 0,000 0,03096186 0,12034608 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03096186 0,12015198 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03096186 0,1199585 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03096186 0,11976564 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03096186 0,1195734 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03096186 0,11938177 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03096186 0,11919076 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03096186 0,11900036 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03096186 0,11881057 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03096186 0,11862138 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03096186 0,11843279 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03096186 0,1182448 ! glycolipid transport GO:0046836 10 7 0,000 0,03096186 0,11805741 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03096186 0,11787061 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03096186 0,1176844 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03096186 0,11749878 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03096186 0,11731374 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03096186 0,11712929 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03096186 0,11694541 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03096186 0,11676211 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03096186 0,11657938 ! mRNA stabilization GO:0048255 18 7 0,000 0,03096186 0,11639723 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03096186 0,11621564 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03096186 0,11603462 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03096186 0,11585416 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03096186 0,11567426 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03096186 0,11549492 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03096186 0,11531614 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03096186 0,11513791 ! lipoprotein transport GO:0042953 14 7 0,000 0,03096186 0,11496022 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03096186 0,11478309 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03096186 0,1146065 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03096186 0,11443045 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03096186 0,11425495 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03096186 0,11407998 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03096186 0,11390554 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03096186 0,11373164 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03096186 0,11355827 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03096186 0,11338543 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03096186 0,11321311 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03096186 0,11304131 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03096186 0,11287004 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03096186 0,11269928 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03096186 0,11252904 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03096186 0,11235931 ! spinal cord patterning GO:0021511 13 7 0,000 0,03096186 0,1121901 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03096186 0,11202139 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03096186 0,11185319 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03096186 0,1116855 ! adrenal gland development GO:0030325 17 7 0,000 0,03096186 0,1115183 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03096186 0,11135161 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03096186 0,11118541 ! ovulation GO:0030728 9 7 0,000 0,03096186 0,11101971 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03096186 0,1108545 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03096186 0,11068979 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03096186 0,11052556 ! microtubule nucleation GO:0007020 20 7 0,000 0,03096186 0,11036182 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03096186 0,11019856 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03096186 0,11003578 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03096186 0,10987349 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03096186 0,10971167 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03096186 0,10955033 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03096186 0,10938946 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03096186 0,10922907 ! galactose metabolic process GO:0006012 13 7 0,000 0,03096186 0,10906914 ! vesicle fusion GO:0006906 17 7 0,000 0,03096186 0,10890969 ! response to dietary excess GO:0002021 8 7 0,000 0,03096186 0,10875069 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03096186 0,10859217 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03096186 0,1084341 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03096186 0,10827649 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03096186 0,10811934 ! organ growth GO:0035265 15 7 0,000 0,03096186 0,10796265 ! purine salvage GO:0043101 10 7 0,000 0,03096186 0,1078064 ! nucleoside transport GO:0015858 8 7 0,000 0,03096186 0,10765062 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03096186 0,10749528 ! parturition GO:0007567 14 7 0,000 0,03096186 0,10734038 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03096186 0,10718594 ! rRNA modification GO:0000154 14 7 0,000 0,03096186 0,10703193 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03096186 0,10687837 ! spindle checkpoint GO:0031577 15 7 0,000 0,03096186 0,10672525 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03096186 0,10657257 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03096186 0,10642032 ! macrophage differentiation GO:0030225 11 7 0,000 0,03096186 0,10626851 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03096186 0,10611713 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03096186 0,10596618 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03096186 0,10581566 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03096186 0,10566557 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03096186 0,1055159 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03096186 0,10536666 ! fibrinolysis GO:0042730 10 7 0,000 0,03096186 0,10521783 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03096186 0,10506943 ! eating behavior GO:0042755 7 7 0,000 0,03096186 0,10492144 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03096186 0,10477388 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03096186 0,10462672 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03096186 0,10447998 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03096186 0,10433365 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03096186 0,10418773 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03096186 0,10404221 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03096186 0,10389711 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03096186 0,1037524 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03096186 0,1036081 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03096186 0,1034642 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03096186 0,1033207 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03096186 0,1031776 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03096186 0,10303489 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03096186 0,10289258 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03096186 0,10275066 ! regulation of meiosis GO:0040020 12 7 0,000 0,03096186 0,10260913 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03096186 0,10246799 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03096186 0,10232723 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03096186 0,10218687 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03096186 0,10204688 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03096186 0,10190729 ! transcription termination GO:0006353 13 7 0,000 0,03096186 0,10176807 ! response to tumor cell GO:0002347 13 7 0,000 0,03096186 0,10162923 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03096186 0,10149077 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03096186 0,10135269 ! anaphase GO:0051322 17 7 0,000 0,03096186 0,10121498 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03096186 0,10107765 ! axonal fasciculation GO:0007413 18 7 0,000 0,03096186 0,10094069 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03096186 0,10080409 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03096186 0,10066787 ! diuresis GO:0030146 12 7 0,000 0,03096186 0,10053202 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03096186 0,10039653 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03096186 0,10026141 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03096186 0,10012665 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03096186 0,09999225 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03096186 0,09985821 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03096186 0,09972453 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03096186 0,09959121 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03096186 0,09945825 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03096186 0,09932563 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03096186 0,09919338 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03096186 0,09906147 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03096186 0,09892991 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03096186 0,09879871 ! lymph node development GO:0048535 10 7 0,000 0,03096186 0,09866785 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03096186 0,09853734 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03096186 0,09840717 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03096186 0,09827734 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03096186 0,09814786 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03096186 0,09801872 ! adult feeding behavior GO:0008343 9 7 0,000 0,03096186 0,09788992 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03096186 0,09776145 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03096186 0,09763332 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03096186 0,09750553 ! muscle adaptation GO:0043500 14 7 0,000 0,03096186 0,09737807 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03096186 0,09725095 ! retina homeostasis GO:0001895 12 7 0,000 0,03096186 0,09712415 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03096186 0,09699769 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03096186 0,09687155 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03096186 0,09674575 ! protein prenylation GO:0018342 18 7 0,000 0,03096186 0,09662027 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03096186 0,09649511 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03096186 0,09637028 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03096186 0,09624577 ! water-soluble vitamin metabolic process GO:0006767 95 62 1,000 0,03165773 0,09828195 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,03165773 0,0981553 ! regulation of mitosis GO:0007088 105 63 1,000 0,03260146 0,10095124 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,03260146 0,10082148 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,03260146 0,10069206 ! positive regulation of cell motion GO:0051272 146 64 1,000 0,03355616 0,10350786 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0353066 0,10876783 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0353066 0,10862874 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0353066 0,10849 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0353066 0,10835162 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0353066 0,1082136 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0353066 0,10807592 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0353066 0,10793859 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0353066 0,10780161 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0353066 0,10766498 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0353066 0,1075287 ! meiotic prophase I GO:0007128 13 8 0,000 0,0353066 0,10739276 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0353066 0,10725716 ! oligopeptide transport GO:0006857 15 8 0,000 0,0353066 0,10712191 ! signal peptide processing GO:0006465 12 8 0,000 0,0353066 0,10698699 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0353066 0,10685242 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0353066 0,10671818 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0353066 0,10658428 ! succinate metabolic process GO:0006105 14 8 0,000 0,0353066 0,10645072 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0353066 0,10631749 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0353066 0,10618459 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0353066 0,10605203 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0353066 0,10591979 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0353066 0,10578789 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0353066 0,10565631 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0353066 0,10552506 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0353066 0,10539413 ! reflex GO:0060004 16 8 0,000 0,0353066 0,10526353 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0353066 0,10513326 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0353066 0,1050033 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0353066 0,10487367 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0353066 0,10474436 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0353066 0,10461536 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0353066 0,10448668 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0353066 0,10435832 ! pigment granule organization GO:0048753 16 8 0,000 0,0353066 0,10423027 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0353066 0,10410254 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0353066 0,10397512 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0353066 0,10384801 ! histidine metabolic process GO:0006547 16 8 0,000 0,0353066 0,10372121 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0353066 0,10359472 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0353066 0,10346854 ! glycine catabolic process GO:0006546 13 8 0,000 0,0353066 0,10334267 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0353066 0,1032171 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0353066 0,10309184 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0353066 0,10296688 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0353066 0,10284222 ! melanin metabolic process GO:0006582 15 8 0,000 0,0353066 0,10271786 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0353066 0,10259381 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0353066 0,10247005 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0353066 0,10234659 ! macrophage activation GO:0042116 12 8 0,000 0,0353066 0,10222343 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0353066 0,10210057 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0353066 0,101978 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0353066 0,10185572 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0353066 0,10173374 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0353066 0,10161205 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0353066 0,10149065 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0353066 0,10136954 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0353066 0,10124872 ! osteoblast development GO:0002076 16 8 0,000 0,0353066 0,10112818 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0353066 0,10100793 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0353066 0,10088797 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0353066 0,10076829 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0353066 0,1006489 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0353066 0,10052979 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0353066 0,10041096 ! response to UV-B GO:0010224 16 8 0,000 0,0353066 0,10029241 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0353066 0,10017414 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0353066 0,10005615 ! intermediate filament organization GO:0045109 12 8 0,000 0,0353066 0,09993844 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0353066 0,099821 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,0353066 0,09970384 ! cellular extravasation GO:0045123 12 8 0,000 0,0353066 0,09958695 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0353066 0,09947034 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0353066 0,099354 ! response to antibiotic GO:0046677 11 8 0,000 0,0353066 0,09923793 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0353066 0,09912214 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0353066 0,09900661 ! DNA topological change GO:0006265 12 8 0,000 0,0353066 0,09889135 ! response to tropane GO:0014073 15 8 0,000 0,0353066 0,09877636 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0353066 0,09866164 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,0353066 0,09854718 ! melanosome transport GO:0032402 13 8 0,000 0,0353066 0,09843299 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,0353066 0,09831907 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0353066 0,0982054 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0353066 0,098092 ! mast cell activation GO:0045576 14 8 0,000 0,0353066 0,09797886 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0353066 0,09786598 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0353066 0,09775336 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0353066 0,097641 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0353066 0,0975289 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0353066 0,09741706 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0353066 0,09730547 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0353066 0,09719413 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0353066 0,09708305 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0353066 0,09697223 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0353066 0,09686166 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0353066 0,09675134 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0353066 0,09664127 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0353066 0,09653145 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0353066 0,09642188 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0353066 0,09631255 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0353066 0,09620348 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0353066 0,09609465 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0353066 0,09598607 ! hormone catabolic process GO:0042447 17 8 0,000 0,0353066 0,09587773 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0353066 0,09576964 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0353066 0,09566179 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0353066 0,09555419 ! ATP catabolic process GO:0006200 11 8 0,000 0,0353066 0,09544682 ! blastocyst growth GO:0001832 19 8 0,000 0,0353066 0,0953397 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0353066 0,09523282 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0353066 0,09512617 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0353066 0,09501977 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0353066 0,0949136 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0353066 0,09480767 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0353066 0,09470198 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0353066 0,09459652 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0353066 0,09449129 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0353066 0,0943863 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0353066 0,09428155 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0353066 0,09417702 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0353066 0,09407273 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0353066 0,09396866 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0353066 0,09386483 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0353066 0,09376123 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0353066 0,09365785 ! fatty acid biosynthetic process GO:0006633 124 66 1,000 0,03549804 0,09406199 ! extracellular matrix organization GO:0030198 133 66 1,000 0,03549804 0,09395851 ! secondary metabolic process GO:0019748 116 66 1,000 0,03549804 0,09385526 ! cell projection assembly GO:0030031 120 66 1,000 0,03549804 0,09375223 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,03648499 0,09625315 ! chromosome segregation GO:0007059 113 67 1,000 0,03648499 0,09614773 ! regulation of lipase activity GO:0060191 130 68 1,000 0,03748245 0,09866824 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,03849032 0,10121061 ! regulation of developmental growth GO:0048638 15 9 0,000 0,039632 0,1040989 ! axon extension GO:0048675 15 9 0,000 0,039632 0,10398538 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,039632 0,10387211 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,039632 0,10375908 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,039632 0,1036463 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,039632 0,10353376 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,039632 0,10342147 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,039632 0,10330942 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,039632 0,10319761 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,039632 0,10308605 ! phosphate transport GO:0006817 19 9 0,000 0,039632 0,10297473 ! reproductive behavior GO:0019098 19 9 0,000 0,039632 0,10286364 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,039632 0,1027528 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,039632 0,10264219 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,039632 0,10253182 ! RNA methylation GO:0001510 15 9 0,000 0,039632 0,10242169 ! elastic fiber assembly GO:0048251 15 9 0,000 0,039632 0,1023118 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,039632 0,10220214 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,039632 0,10209272 ! artery development GO:0060840 24 9 0,000 0,039632 0,10198353 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,039632 0,10187457 ! regulation of glycolysis GO:0006110 21 9 0,000 0,039632 0,10176584 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,039632 0,10165735 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,039632 0,10154909 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,039632 0,10144106 ! chemosensory behavior GO:0007635 20 9 0,000 0,039632 0,10133326 ! microtubule bundle formation GO:0001578 21 9 0,000 0,039632 0,10122569 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,039632 0,10111834 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,039632 0,10101122 ! leukocyte degranulation GO:0043299 16 9 0,000 0,039632 0,10090433 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,039632 0,10079767 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,039632 0,10069123 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,039632 0,10058502 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,039632 0,10047903 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,039632 0,10037326 ! protein targeting to ER GO:0045047 22 9 0,000 0,039632 0,10026771 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,039632 0,10016239 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,039632 0,10005729 ! T cell selection GO:0045058 23 9 0,000 0,039632 0,09995241 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,039632 0,09984774 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,039632 0,0997433 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,039632 0,09963908 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,039632 0,09953507 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,039632 0,09943128 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,039632 0,0993277 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,039632 0,09922435 ! mannose metabolic process GO:0006013 13 9 0,000 0,039632 0,0991212 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,039632 0,09901827 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,039632 0,09891556 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,039632 0,09881305 ! receptor clustering GO:0043113 18 9 0,000 0,039632 0,09871076 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,039632 0,09860868 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,039632 0,09850681 ! ruffle organization GO:0031529 15 9 0,000 0,039632 0,09840516 ! retinol metabolic process GO:0042572 18 9 0,000 0,039632 0,09830371 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,039632 0,09820247 ! behavioral fear response GO:0001662 22 9 0,000 0,039632 0,09810144 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,039632 0,09800061 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,039632 0,0979 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,039632 0,09779959 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,039632 0,09769938 ! protein heterooligomerization GO:0051291 16 9 0,000 0,039632 0,09759938 ! oligodendrocyte development GO:0014003 10 9 0,000 0,039632 0,09749959 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,039632 0,0974 ! segment specification GO:0007379 13 9 0,000 0,039632 0,09730061 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,039632 0,09720142 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,039632 0,09710244 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,039632 0,09700366 ! response to amine stimulus GO:0014075 13 9 0,000 0,039632 0,09690508 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,039632 0,0968067 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,039632 0,09670852 ! erythrocyte development GO:0048821 15 9 0,000 0,039632 0,09661053 ! gas homeostasis GO:0033483 16 9 0,000 0,039632 0,09651275 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,039632 0,09641516 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,039632 0,09631777 ! renal water homeostasis GO:0003091 14 9 0,000 0,039632 0,09622058 ! postreplication repair GO:0006301 22 9 0,000 0,039632 0,09612358 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,039632 0,09602678 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,039632 0,09593018 ! icosanoid secretion GO:0032309 15 9 0,000 0,039632 0,09583376 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,039632 0,09573755 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,039632 0,09564152 ! regulation of cell division GO:0051302 15 9 0,000 0,039632 0,09554569 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,039632 0,09545005 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,039632 0,0953546 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,039632 0,09525934 ! sterol catabolic process GO:0016127 11 9 0,000 0,039632 0,09516427 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,039632 0,09506939 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,039632 0,0949747 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,039632 0,09488019 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,039632 0,09478588 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,039632 0,09469175 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,039632 0,09459781 ! musculoskeletal movement GO:0050881 14 9 0,000 0,039632 0,09450406 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,039632 0,09441049 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,039632 0,09431711 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,039632 0,09422391 ! purine base metabolic process GO:0006144 21 9 0,000 0,039632 0,09413089 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,039632 0,09403806 ! pigment granule transport GO:0051904 17 9 0,000 0,039632 0,09394541 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,039632 0,09385295 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,039632 0,09376066 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,039632 0,09366856 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,039632 0,09357664 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,039632 0,0934849 ! mitochondrion localization GO:0051646 15 9 0,000 0,039632 0,09339334 ! amine catabolic process GO:0009310 117 71 1,000 0,04053684 0,09543212 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,04053684 0,09533883 ! regulation of caspase activity GO:0043281 122 72 1,000 0,04157526 0,09768562 ! regulation of blood pressure GO:0008217 125 73 1,000 0,04262365 0,10005121 ! axon guidance GO:0007411 139 73 1,000 0,04262365 0,0999537 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,04368189 0,10233557 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 1,000 0,04368189 0,10223602 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,04368189 0,10213666 ! organelle localization GO:0051640 136 74 1,000 0,04368189 0,1020375 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04393816 0,10253657 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,04393816 0,10243721 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04393816 0,10233805 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04393816 0,10223907 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,04393816 0,10214029 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04393816 0,1020417 ! synapsis GO:0007129 13 10 0,000 0,04393816 0,1019433 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04393816 0,10184509 ! N-glycan processing GO:0006491 20 10 0,000 0,04393816 0,10174707 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04393816 0,10164923 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04393816 0,10155159 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04393816 0,10145413 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04393816 0,10135686 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04393816 0,10125977 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04393816 0,10116287 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04393816 0,10106616 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04393816 0,10096963 ! androgen metabolic process GO:0008209 17 10 0,000 0,04393816 0,10087328 ! phospholipid efflux GO:0033700 16 10 0,000 0,04393816 0,10077712 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04393816 0,10068114 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04393816 0,10058535 ! lung alveolus development GO:0048286 26 10 0,000 0,04393816 0,10048974 ! pathogenesis GO:0009405 13 10 0,000 0,04393816 0,1003943 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04393816 0,10029905 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04393816 0,10020398 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04393816 0,10010909 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04393816 0,10001438 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04393816 0,09991985 ! endoderm development GO:0007492 16 10 0,000 0,04393816 0,0998255 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04393816 0,09973132 ! arginine catabolic process GO:0006527 13 10 0,000 0,04393816 0,09963733 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04393816 0,0995435 ! proline metabolic process GO:0006560 13 10 0,000 0,04393816 0,09944986 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04393816 0,09935639 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04393816 0,0992631 ! V(D)J recombination GO:0033151 28 10 0,000 0,04393816 0,09916998 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04393816 0,09907704 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04393816 0,09898427 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04393816 0,09889168 ! B cell proliferation GO:0042100 18 10 0,000 0,04393816 0,09879925 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04393816 0,098707 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04393816 0,09861493 ! multicellular organism growth GO:0035264 18 10 0,000 0,04393816 0,09852302 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04393816 0,09843129 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04393816 0,09833972 ! epithelial cell development GO:0002064 20 10 0,000 0,04393816 0,09824833 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04393816 0,09815711 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04393816 0,09806605 ! macroautophagy GO:0016236 17 10 0,000 0,04393816 0,09797516 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04393816 0,09788445 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04393816 0,0977939 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04393816 0,09770351 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04393816 0,0976133 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04393816 0,09752325 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04393816 0,09743337 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04393816 0,09734365 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04393816 0,0972541 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04393816 0,09716471 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04393816 0,09707548 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04393816 0,09698642 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04393816 0,09689753 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04393816 0,09680879 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04393816 0,09672022 ! response to dsRNA GO:0043331 20 10 0,000 0,04393816 0,09663181 ! DNA ligation GO:0006266 19 10 0,000 0,04393816 0,09654356 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04393816 0,09645548 ! melanosome localization GO:0032400 16 10 0,000 0,04393816 0,09636755 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04393816 0,09627978 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04393816 0,09619218 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04393816 0,09610473 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04393816 0,09601744 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04393816 0,09593031 ! mRNA cleavage GO:0006379 17 10 0,000 0,04393816 0,09584334 ! protein sumoylation GO:0016925 15 10 0,000 0,04393816 0,09575652 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04393816 0,09566987 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04393816 0,09558337 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04393816 0,09549702 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04393816 0,09541083 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04393816 0,0953248 ! salivary gland development GO:0007431 27 10 0,000 0,04393816 0,09523892 ! prophase GO:0051324 15 10 0,000 0,04393816 0,0951532 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04393816 0,09506763 ! apical protein localization GO:0045176 15 10 0,000 0,04393816 0,09498221 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04393816 0,09489695 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04393816 0,09481184 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04393816 0,09472688 ! midbrain development GO:0030901 13 10 0,000 0,04393816 0,09464208 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04393816 0,09455743 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04393816 0,09447292 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04393816 0,09438857 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04393816 0,09430437 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04393816 0,09422032 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04393816 0,09413642 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,04393816 0,09405267 ! oocyte development GO:0048599 17 10 0,000 0,04393816 0,09396907 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04393816 0,09388561 ! blastocyst formation GO:0001825 17 10 0,000 0,04393816 0,09380231 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04393816 0,09371915 ! activation of innate immune response GO:0002218 12 10 0,000 0,04393816 0,09363614 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04393816 0,09355328 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04393816 0,09347056 ! response to nicotine GO:0035094 20 10 0,000 0,04393816 0,09338799 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04393816 0,09330556 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04393816 0,09322328 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04393816 0,09314115 ! meiotic cell cycle GO:0051321 122 75 1,000 0,04474988 0,09477836 ! rhythmic process GO:0048511 128 75 1,000 0,04474988 0,094695 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,04801127 0,10150713 ! protein oligomerization GO:0051259 139 78 1,000 0,04801127 0,10141801 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04822514 0,10178043 ! respiratory burst GO:0045730 17 11 0,000 0,04822514 0,10169123 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04822514 0,10160219 ! neuron fate specification GO:0048665 17 11 0,000 0,04822514 0,10151329 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04822514 0,10142456 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04822514 0,10133598 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04822514 0,10124755 ! thyroid gland development GO:0030878 26 11 0,000 0,04822514 0,10115928 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04822514 0,10107116 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04822514 0,1009832 ! response to pain GO:0048265 24 11 0,000 0,04822514 0,10089539 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04822514 0,10080773 ! T cell proliferation GO:0042098 26 11 0,000 0,04822514 0,10072022 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04822514 0,10063287 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04822514 0,10054566 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04822514 0,10045861 ! bone resorption GO:0045453 16 11 0,000 0,04822514 0,10037171 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04822514 0,10028496 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04822514 0,10019836 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04822514 0,1001119 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04822514 0,1000256 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04822514 0,09993944 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04822514 0,09985344 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04822514 0,09976758 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04822514 0,09968187 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04822514 0,0995963 ! lipid digestion GO:0044241 18 11 0,000 0,04822514 0,09951089 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04822514 0,09942562 ! UV protection GO:0009650 19 11 0,000 0,04822514 0,09934049 ! adult heart development GO:0007512 14 11 0,000 0,04822514 0,09925551 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04822514 0,09917068 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04822514 0,09908599 ! temperature homeostasis GO:0001659 17 11 0,000 0,04822514 0,09900145 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04822514 0,09891705 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04822514 0,09883279 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04822514 0,09874868 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04822514 0,09866471 ! regulation of organ growth GO:0046620 13 11 0,000 0,04822514 0,09858088 ! pigment granule localization GO:0051875 20 11 0,000 0,04822514 0,09849719 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04822514 0,09841365 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04822514 0,09833025 ! embryonic axis specification GO:0000578 18 11 0,000 0,04822514 0,09824699 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04822514 0,09816387 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04822514 0,09808089 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04822514 0,09799805 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04822514 0,09791535 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04822514 0,0978328 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04822514 0,09775038 ! zymogen activation GO:0031638 15 11 0,000 0,04822514 0,09766809 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04822514 0,09758595 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04822514 0,09750395 ! nucleosome positioning GO:0016584 15 11 0,000 0,04822514 0,09742208 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04822514 0,09734035 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04822514 0,09725876 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04822514 0,0971773 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04822514 0,09709598 ! acid secretion GO:0046717 18 11 0,000 0,04822514 0,0970148 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04822514 0,09693375 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04822514 0,09685283 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04822514 0,09677206 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04822514 0,09669141 ! oocyte differentiation GO:0009994 18 11 0,000 0,04822514 0,0966109 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04822514 0,09653053 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04822514 0,09645029 ! cholesterol efflux GO:0033344 19 11 0,000 0,04822514 0,09637018 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04822514 0,0962902 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04822514 0,09621036 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04822514 0,09613065 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04822514 0,09605107 ! embryonic gut development GO:0048566 15 11 0,000 0,04822514 0,09597163 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04822514 0,09589231 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04822514 0,09581313 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04822514 0,09573407 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04822514 0,09565515 ! defense response to fungus GO:0050832 13 11 0,000 0,04822514 0,09557636 ! lysogeny GO:0030069 21 11 0,000 0,04822514 0,09549769 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04822514 0,09541916 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04822514 0,09534075 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04822514 0,09526248 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04822514 0,09518433 ! regulation of embryonic development GO:0045995 27 11 0,000 0,04822514 0,09510631 ! nucleus localization GO:0051647 19 11 0,000 0,04822514 0,09502842 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04822514 0,09495065 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,04911718 0,09662792 ! muscle cell differentiation GO:0042692 159 80 1,000 0,05023232 0,09874098 ! protein import into nucleus GO:0006606 158 80 1,000 0,05023232 0,09866037 ! response to hypoxia GO:0001666 171 81 1,000 0,05135657 0,10078622 ! nuclear import GO:0051170 161 81 1,000 0,05135657 0,10070408 ! response to drug GO:0042493 143 82 1,000 0,05248983 0,10284245 ! response to nutrient GO:0007584 125 82 1,000 0,05248983 0,10275878 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05249305 0,10268153 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05249305 0,10259811 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05249305 0,10251484 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,05249305 0,10243169 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05249305 0,10234869 ! virus-host interaction GO:0019048 29 12 0,000 0,05249305 0,10226581 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,05249305 0,10218307 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05249305 0,10210047 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05249305 0,102018 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05249305 0,10193566 ! protein complex disassembly GO:0043241 27 12 0,000 0,05249305 0,10185345 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05249305 0,10177138 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,05249305 0,10168944 ! hippocampus development GO:0021766 26 12 0,000 0,05249305 0,10160763 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05249305 0,10152595 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05249305 0,1014444 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05249305 0,10136299 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05249305 0,1012817 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05249305 0,10120054 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05249305 0,10111952 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05249305 0,10103862 ! drug transport GO:0015893 16 12 0,000 0,05249305 0,10095786 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05249305 0,10087722 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05249305 0,10079671 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05249305 0,10071633 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05249305 0,10063608 ! focal adhesion formation GO:0048041 35 12 0,000 0,05249305 0,10055595 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05249305 0,10047596 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05249305 0,10039609 ! forebrain cell migration GO:0021885 21 12 0,000 0,05249305 0,10031635 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05249305 0,10023673 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05249305 0,10015724 ! entry into host cell GO:0030260 32 12 0,000 0,05249305 0,10007788 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,05249305 0,09999864 ! monoamine transport GO:0015844 18 12 0,000 0,05249305 0,09991952 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05249305 0,09984054 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05249305 0,09976167 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05249305 0,09968294 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05249305 0,09960432 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05249305 0,09952583 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05249305 0,09944746 ! protein homotetramerization GO:0051289 21 12 0,000 0,05249305 0,09936922 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05249305 0,0992911 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05249305 0,0992131 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05249305 0,09913523 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05249305 0,09905747 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05249305 0,09897984 ! cranial nerve development GO:0021545 20 12 0,000 0,05249305 0,09890233 ! fucose catabolic process GO:0019317 22 12 0,000 0,05249305 0,09882494 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05249305 0,09874768 ! histone methylation GO:0016571 26 12 0,000 0,05249305 0,09867053 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05249305 0,0985935 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05249305 0,0985166 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,05249305 0,09843981 ! T cell homeostasis GO:0043029 25 12 0,000 0,05249305 0,09836315 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05249305 0,0982866 ! spleen development GO:0048536 22 12 0,000 0,05249305 0,09821017 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05249305 0,09813386 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05249305 0,09805767 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05249305 0,0979816 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05249305 0,09790564 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,05249305 0,09782981 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05249305 0,09775409 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05249305 0,09767848 ! response to cold GO:0009409 17 12 0,000 0,05249305 0,097603 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05249305 0,09752763 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05249305 0,09745238 ! response to oxygen levels GO:0070482 176 83 1,000 0,05363201 0,09949006 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05674196 0,10517809 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05674196 0,10509712 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05674196 0,10501627 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05674196 0,10493555 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05674196 0,10485496 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05674196 0,10477449 ! lipid localization GO:0010876 28 13 0,000 0,05674196 0,10469414 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05674196 0,10461391 ! organelle fusion GO:0048284 32 13 0,000 0,05674196 0,10453381 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05674196 0,10445383 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05674196 0,10437397 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05674196 0,10429424 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05674196 0,10421462 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05674196 0,10413513 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05674196 0,10405576 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05674196 0,10397651 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05674196 0,10389738 ! methionine metabolic process GO:0006555 27 13 0,000 0,05674196 0,10381837 ! plasma membrane organization GO:0007009 24 13 0,000 0,05674196 0,10373948 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05674196 0,10366071 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05674196 0,10358206 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05674196 0,10350353 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05674196 0,10342512 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05674196 0,10334683 ! response to X-ray GO:0010165 25 13 0,000 0,05674196 0,10326865 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05674196 0,10319059 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05674196 0,10311266 ! exocrine system development GO:0035272 32 13 0,000 0,05674196 0,10303484 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,05674196 0,10295713 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05674196 0,10287955 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05674196 0,10280208 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05674196 0,10272472 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05674196 0,10264749 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05674196 0,10257037 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05674196 0,10249336 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05674196 0,10241647 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05674196 0,1023397 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05674196 0,10226304 ! regulation of cellular pH GO:0030641 22 13 0,000 0,05674196 0,10218649 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05674196 0,10211007 ! ribosome assembly GO:0042255 17 13 0,000 0,05674196 0,10203375 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05674196 0,10195755 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05674196 0,10188146 ! chromatin silencing GO:0006342 26 13 0,000 0,05674196 0,10180549 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05674196 0,10172963 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05674196 0,10165388 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05674196 0,10157824 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05674196 0,10150272 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05674196 0,10142731 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05674196 0,10135201 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05674196 0,10127682 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05674196 0,10120175 ! embryonic placenta development GO:0001892 23 13 0,000 0,05674196 0,10112678 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05674196 0,10105193 ! insulin secretion GO:0030073 23 13 0,000 0,05674196 0,10097719 ! actin filament polymerization GO:0030041 24 13 0,000 0,05674196 0,10090256 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05674196 0,10082803 ! acrosome reaction GO:0007340 18 13 0,000 0,05674196 0,10075362 ! amine biosynthetic process GO:0009309 138 86 1,000 0,05711098 0,10133408 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,05828779 0,10334593 ! protein localization in nucleus GO:0034504 176 87 1,000 0,05828779 0,10326983 ! regulation of DNA binding GO:0051101 155 88 1,000 0,05947301 0,10529218 ! gland development GO:0048732 206 88 1,000 0,05947301 0,10521476 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,06066655 0,1072474 ! rRNA transcription GO:0009303 25 14 0,000 0,06097196 0,10770817 ! lactation GO:0007595 26 14 0,000 0,06097196 0,10762915 ! reproductive cellular process GO:0048610 20 14 0,000 0,06097196 0,10755024 ! tRNA modification GO:0006400 20 14 0,000 0,06097196 0,10747145 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06097196 0,10739277 ! regulation of S phase GO:0033261 23 14 0,000 0,06097196 0,10731421 ! water transport GO:0006833 21 14 0,000 0,06097196 0,10723577 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06097196 0,10715744 ! non-recombinational repair GO:0000726 25 14 0,000 0,06097196 0,10707922 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06097196 0,10700112 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06097196 0,10692313 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06097196 0,10684525 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,06097196 0,10676749 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06097196 0,10668984 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06097196 0,1066123 ! palate development GO:0060021 31 14 0,000 0,06097196 0,10653488 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06097196 0,10645757 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06097196 0,10638037 ! arginine metabolic process GO:0006525 17 14 0,000 0,06097196 0,10630328 ! regulation of heart rate GO:0002027 24 14 0,000 0,06097196 0,10622631 ! organic alcohol transport GO:0015850 29 14 0,000 0,06097196 0,10614944 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06097196 0,10607269 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,06097196 0,10599605 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06097196 0,10591952 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06097196 0,1058431 ! L-amino acid transport GO:0015807 30 14 0,000 0,06097196 0,10576678 ! bone mineralization GO:0030282 17 14 0,000 0,06097196 0,10569058 ! stem cell development GO:0048864 43 14 0,000 0,06097196 0,10561449 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06097196 0,10553851 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,06097196 0,10546264 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06097196 0,10538688 ! cerebellum development GO:0021549 21 14 0,000 0,06097196 0,10531122 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06097196 0,10523567 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06097196 0,10516024 ! response to gamma radiation GO:0010332 28 14 0,000 0,06097196 0,10508491 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06097196 0,10500969 ! cofactor transport GO:0051181 26 14 0,000 0,06097196 0,10493457 ! NADP metabolic process GO:0006739 24 14 0,000 0,06097196 0,10485956 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06097196 0,10478466 ! intestinal absorption GO:0050892 25 14 0,000 0,06097196 0,10470987 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06097196 0,10463519 ! oxygen transport GO:0015671 21 14 0,000 0,06097196 0,10456061 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06097196 0,10448613 ! male genitalia development GO:0030539 24 14 0,000 0,06097196 0,10441177 ! regulation of RNA stability GO:0043487 32 14 0,000 0,06097196 0,1043375 ! regulation of axon extension GO:0030516 37 14 0,000 0,06097196 0,10426335 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,06097196 0,1041893 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06097196 0,10411535 ! ossification GO:0001503 188 90 1,000 0,0618683 0,10557101 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,0618683 0,10549619 ! bone development GO:0060348 189 91 1,000 0,06307817 0,10748306 ! vitamin metabolic process GO:0006766 139 92 1,000 0,06429607 0,10948077 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06518313 0,11091273 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06518313 0,11083435 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,06518313 0,11075607 ! superoxide anion generation GO:0042554 20 15 0,000 0,06518313 0,11067791 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,06518313 0,11059986 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06518313 0,11052192 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06518313 0,11044408 ! copper ion transport GO:0006825 20 15 0,000 0,06518313 0,11036636 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06518313 0,11028875 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06518313 0,11021124 ! sulfate transport GO:0008272 23 15 0,000 0,06518313 0,11013385 ! response to cAMP GO:0051591 22 15 0,000 0,06518313 0,11005656 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06518313 0,10997938 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06518313 0,10990231 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06518313 0,10982535 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,06518313 0,1097485 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06518313 0,10967175 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06518313 0,10959511 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06518313 0,10951858 ! pituitary gland development GO:0021983 29 15 0,000 0,06518313 0,10944215 ! vesicle coating GO:0006901 33 15 0,000 0,06518313 0,10936583 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06518313 0,10928962 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06518313 0,10921351 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,06518313 0,10913751 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06518313 0,10906161 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,06518313 0,10898582 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06518313 0,10891014 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06518313 0,10883456 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06518313 0,10875908 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06518313 0,10868371 ! histone deacetylation GO:0016575 20 15 0,000 0,06518313 0,10860845 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06518313 0,10853329 ! tissue regeneration GO:0042246 26 15 0,000 0,06518313 0,10845823 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06518313 0,10838328 ! water homeostasis GO:0030104 27 15 0,000 0,06518313 0,10830843 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06518313 0,10823368 ! muscle maintenance GO:0046716 26 15 0,000 0,06518313 0,10815903 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06518313 0,10808449 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06518313 0,10801006 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06518313 0,10793572 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06518313 0,10786149 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06518313 0,10778735 ! cell killing GO:0001906 29 15 0,000 0,06518313 0,10771332 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,06518313 0,1076394 ! detection of bacterium GO:0016045 18 15 0,000 0,06518313 0,10756557 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,06518313 0,10749184 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06518313 0,10741822 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06518313 0,1073447 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06518313 0,10727127 ! peptide hormone processing GO:0016486 23 15 0,000 0,06518313 0,10719795 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,06552189 0,10768147 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,06552189 0,10760797 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,06675555 0,10955925 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 1,000 0,069246 0,11356911 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06937555 0,11370406 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06937555 0,11362666 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06937555 0,11354937 ! bone remodeling GO:0046849 27 16 0,000 0,06937555 0,11347217 ! filopodium assembly GO:0046847 32 16 0,000 0,06937555 0,11339509 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06937555 0,1133181 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06937555 0,11324123 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06937555 0,11316445 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06937555 0,11308778 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06937555 0,11301122 ! startle response GO:0001964 28 16 0,000 0,06937555 0,11293475 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06937555 0,1128584 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06937555 0,11278214 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06937555 0,11270599 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06937555 0,11262994 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06937555 0,11255399 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06937555 0,11247814 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06937555 0,1124024 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06937555 0,11232676 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06937555 0,11225122 ! response to osmotic stress GO:0006970 25 16 0,000 0,06937555 0,11217578 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06937555 0,11210045 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06937555 0,11202521 ! fructose metabolic process GO:0006000 25 16 0,000 0,06937555 0,11195008 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06937555 0,11187504 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06937555 0,11180011 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06937555 0,11172528 ! axon cargo transport GO:0008088 43 16 0,000 0,06937555 0,11165055 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06937555 0,11157591 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06937555 0,11150138 ! DNA replication initiation GO:0006270 27 16 0,000 0,06937555 0,11142695 ! neuron recognition GO:0008038 35 16 0,000 0,06937555 0,11135261 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06937555 0,11127838 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06937555 0,11120424 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06937555 0,1111302 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,06937555 0,11105627 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06937555 0,11098242 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06937555 0,11090868 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06937555 0,11083504 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06937555 0,11076149 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06937555 0,11068804 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06937555 0,11061469 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,06937555 0,11054143 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06937555 0,11046828 ! defense response to virus GO:0051607 37 16 0,000 0,06937555 0,11039522 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 1,000 0,07050261 0,11211453 ! protein ubiquitination GO:0016567 217 97 1,000 0,07050261 0,11204047 ! response to virus GO:0009615 160 98 1,000 0,07176668 0,11397401 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 1,000 0,07176668 0,11389883 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,07176668 0,11382375 GO:0016054|organic acid catabolic process, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07354931 0,1165742 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,07354931 0,11649745 ! metencephalon development GO:0022037 30 17 0,000 0,07354931 0,11642081 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,07354931 0,11634427 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07354931 0,11626782 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07354931 0,11619148 ! signal complex assembly GO:0007172 41 17 0,000 0,07354931 0,11611524 ! endothelial cell migration GO:0043542 28 17 0,000 0,07354931 0,1160391 ! inositol metabolic process GO:0006020 28 17 0,000 0,07354931 0,11596306 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07354931 0,11588712 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07354931 0,11581128 ! glial cell development GO:0021782 27 17 0,000 0,07354931 0,11573553 ! limbic system development GO:0021761 36 17 0,000 0,07354931 0,11565989 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07354931 0,11558434 ! adult walking behavior GO:0007628 33 17 0,000 0,07354931 0,1155089 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07354931 0,11543355 ! heart looping GO:0001947 30 17 0,000 0,07354931 0,1153583 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07354931 0,11528315 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,07354931 0,11520809 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07354931 0,11513314 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,07354931 0,11505828 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,07354931 0,11498351 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07354931 0,11490885 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07354931 0,11483428 ! glycine metabolic process GO:0006544 28 17 0,000 0,07354931 0,11475981 ! membrane budding GO:0006900 37 17 0,000 0,07354931 0,11468544 ! DNA integration GO:0015074 29 17 0,000 0,07354931 0,11461116 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,07354931 0,11453698 ! regulation of protein binding GO:0043393 33 17 0,000 0,07354931 0,11446289 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07354931 0,1143889 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07354931 0,11431501 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07354931 0,11424121 ! genitalia development GO:0048806 30 17 0,000 0,07354931 0,1141675 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,07354931 0,11409389 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07354931 0,11402038 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07354931 0,11394696 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,07354931 0,11387364 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,07354931 0,1138004 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07354931 0,11372727 ! steroid catabolic process GO:0006706 31 17 0,000 0,07354931 0,11365423 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,07354931 0,11358128 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,07354931 0,11350842 ! gas transport GO:0015669 25 17 0,000 0,07354931 0,11343566 ! organic cation transport GO:0015695 31 17 0,000 0,07354931 0,11336299 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07354931 0,11329042 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,07354931 0,11321793 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07354931 0,11314554 ! microspike assembly GO:0030035 36 17 0,000 0,07354931 0,11307325 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07354931 0,11300104 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,07354931 0,11292893 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07770448 0,11923277 ! neuron maturation GO:0042551 42 18 0,000 0,07770448 0,11915678 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,07770448 0,11908088 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,07770448 0,11900508 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,07770448 0,11892938 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07770448 0,11885377 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,07770448 0,11877826 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07770448 0,11870285 ! memory GO:0007613 31 18 0,000 0,07770448 0,11862753 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07770448 0,11855231 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07770448 0,11847718 ! patterning of blood vessels GO:0001569 39 18 0,000 0,07770448 0,11840214 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07770448 0,11832721 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,07770448 0,11825236 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,07770448 0,11817761 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,07770448 0,11810296 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07770448 0,1180284 ! response to retinoic acid GO:0032526 26 18 0,000 0,07770448 0,11795393 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,07770448 0,11787956 ! response to fungus GO:0009620 21 18 0,000 0,07770448 0,11780528 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,07770448 0,1177311 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07770448 0,11765701 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,07770448 0,11758301 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,07770448 0,11750911 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07770448 0,11743529 ! vitamin transport GO:0051180 27 18 0,000 0,07770448 0,11736157 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,07770448 0,11728795 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07770448 0,11721441 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,07770448 0,11714097 ! nerve development GO:0021675 28 18 0,000 0,07770448 0,11706762 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07770448 0,11699436 ! protein secretion GO:0009306 39 19 0,000 0,08184116 0,12314561 ! positive regulation of translation GO:0045727 30 19 0,000 0,08184116 0,12306865 ! negative regulation of defense response GO:0031348 25 19 0,000 0,08184116 0,12299178 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,08184116 0,122915 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,08184116 0,12283833 ! skin development GO:0043588 36 19 0,000 0,08184116 0,12276174 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,08184116 0,12268526 ! lipid phosphorylation GO:0046834 35 19 0,000 0,08184116 0,12260886 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08184116 0,12253257 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,08184116 0,12245637 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,08184116 0,12238026 ! bile acid metabolic process GO:0008206 29 19 0,000 0,08184116 0,12230425 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08184116 0,12222833 ! cerebral cortex development GO:0021987 36 19 0,000 0,08184116 0,1221525 ! pigmentation during development GO:0048066 41 19 0,000 0,08184116 0,12207677 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,08184116 0,12200114 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,08184116 0,12192559 ! heme metabolic process GO:0042168 36 19 0,000 0,08184116 0,12185015 ! actin filament bundle formation GO:0051017 42 19 0,000 0,08184116 0,12177479 ! neuromuscular junction development GO:0007528 34 19 0,000 0,08184116 0,12169953 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,08184116 0,12162436 ! plasma membrane fusion GO:0045026 28 19 0,000 0,08184116 0,12154928 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,08184116 0,1214743 ! peptide cross-linking GO:0018149 37 19 0,000 0,08184116 0,12139941 ! protein export from nucleus GO:0006611 36 19 0,000 0,08184116 0,12132461 ! heart process GO:0003015 30 19 0,000 0,08184116 0,1212499 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08184116 0,12117528 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08184116 0,12110076 ! visual learning GO:0008542 36 19 0,000 0,08184116 0,12102633 ! cellular pigmentation GO:0033059 36 19 0,000 0,08184116 0,12095199 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,08184116 0,12087774 ! cell-cell junction organization GO:0045216 35 19 0,000 0,08184116 0,12080358 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,08184116 0,12072951 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,08184116 0,12065554 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08184116 0,12058165 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,08184116 0,12050786 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,08184116 0,12043415 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,08184116 0,12036054 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08184116 0,12028701 ! cilium assembly GO:0042384 37 19 0,000 0,08184116 0,12021357 ! peptide hormone secretion GO:0030072 31 19 0,000 0,08184116 0,12014023 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08595942 0,12610876 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08595942 0,12603192 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08595942 0,12595516 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08595942 0,1258785 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08595942 0,12580193 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08595942 0,12572546 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08595942 0,12564907 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,08595942 0,12557278 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08595942 0,12549659 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08595942 0,12542048 ! response to alkaloid GO:0043279 38 20 0,000 0,08595942 0,12534447 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08595942 0,12526855 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,08595942 0,12519272 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,08595942 0,12511698 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08595942 0,12504134 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08595942 0,12496578 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08595942 0,12489032 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,08595942 0,12481495 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08595942 0,12473967 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08595942 0,12466448 ! body fluid secretion GO:0007589 31 20 0,000 0,08595942 0,12458938 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08595942 0,12451437 ! peptide secretion GO:0002790 35 20 0,000 0,08595942 0,12443945 ! stem cell differentiation GO:0048863 53 20 0,000 0,08595942 0,12436463 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08595942 0,12428989 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08595942 0,12421524 ! sensory perception of pain GO:0019233 30 20 0,000 0,08595942 0,12414068 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08595942 0,12406621 ! diencephalon development GO:0021536 34 20 0,000 0,08595942 0,12399183 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08595942 0,12391754 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08595942 0,12384334 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08595942 0,12376922 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08595942 0,1236952 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08595942 0,12362126 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08595942 0,12354742 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08595942 0,12347366 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08595942 0,12339998 ! regulation of glucose import GO:0046324 29 20 0,000 0,08595942 0,1233264 GO:0010827|regulation of glucose transport, ! actin filament-based movement GO:0030048 43 20 0,000 0,08595942 0,1232529 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,08595942 0,1231795 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08595942 0,12310617 ! negative regulation of translation GO:0017148 29 20 0,000 0,08595942 0,12303294 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,08595942 0,12295979 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,08595942 0,12288673 ! regulation of cell killing GO:0031341 42 21 0,000 0,09005935 0,12867149 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,09005935 0,12859513 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,09005935 0,12851886 ! hormone secretion GO:0046879 38 21 0,000 0,09005935 0,12844268 ! glycerol metabolic process GO:0006071 34 21 0,000 0,09005935 0,12836659 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,09005935 0,12829058 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,09005935 0,12821467 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,09005935 0,12813885 ! axis specification GO:0009798 38 21 0,000 0,09005935 0,12806312 ! ovarian follicle development GO:0001541 35 21 0,000 0,09005935 0,12798748 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,09005935 0,12791192 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,09005935 0,12783646 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,09005935 0,12776108 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,09005935 0,1276858 ! cell aging GO:0007569 44 21 0,000 0,09005935 0,1276106 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,09005935 0,12753549 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,09005935 0,12746047 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,09005935 0,12738554 ! cytolysis GO:0019835 24 21 0,000 0,09005935 0,12731069 ! vasodilation GO:0042311 39 21 0,000 0,09005935 0,12723593 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,09005935 0,12716127 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,09005935 0,12708668 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,09005935 0,12701219 ! oogenesis GO:0048477 36 21 0,000 0,09005935 0,12693778 ! DNA modification GO:0006304 34 21 0,000 0,09005935 0,12686346 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,09005935 0,12678923 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,09005935 0,12671509 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,09005935 0,12664103 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,09005935 0,12656705 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,09005935 0,12649317 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,09005935 0,12641937 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,09005935 0,12634565 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,09005935 0,12627203 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,09005935 0,12619848 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,09005935 0,12612503 ! collagen catabolic process GO:0030574 28 21 0,000 0,09005935 0,12605166 ! sperm-egg recognition GO:0035036 21 21 0,000 0,09005935 0,12597837 ! gut development GO:0048565 39 21 0,000 0,09005935 0,12590517 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,09414102 0,13153502 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,09414102 0,13145868 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09414102 0,13138242 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09414102 0,13130626 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,09414102 0,13123018 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,09414102 0,1311542 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09414102 0,1310783 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,09414102 0,13100249 ! regeneration GO:0031099 41 22 0,000 0,09414102 0,13092676 ! keratinization GO:0031424 28 22 0,000 0,09414102 0,13085113 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,09414102 0,13077558 ! sensory perception of taste GO:0050909 28 22 0,000 0,09414102 0,13070011 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,09414102 0,13062474 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09414102 0,13054945 ! vacuolar transport GO:0007034 36 22 0,000 0,09414102 0,13047425 ! lysosome organization GO:0007040 41 22 0,000 0,09414102 0,13039914 ! central nervous system neuron development GO:0021954 46 22 0,000 0,09414102 0,13032411 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,09414102 0,13024916 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,09414102 0,13017431 ! fucose metabolic process GO:0006004 39 22 0,000 0,09414102 0,13009954 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09414102 0,13002486 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,09414102 0,12995026 ! ureteric bud development GO:0001657 43 22 0,000 0,09414102 0,12987574 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09414102 0,12980132 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,09414102 0,12972697 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,09414102 0,12965272 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,09414102 0,12957855 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09414102 0,12950446 ! sarcomere organization GO:0045214 30 22 0,000 0,09414102 0,12943046 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,09414102 0,12935654 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,09414102 0,1292827 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,09414102 0,12920895 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,09414102 0,12913529 ! protein stabilization GO:0050821 39 22 0,000 0,09414102 0,12906171 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,09820452 0,13455585 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,09820452 0,13447927 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,09820452 0,13440277 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,09820452 0,13432636 ! viral genome replication GO:0019079 41 23 0,000 0,09820452 0,13425004 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09820452 0,13417381 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09820452 0,13409766 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09820452 0,1340216 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,09820452 0,13394562 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09820452 0,13386973 ! visual behavior GO:0007632 42 23 0,000 0,09820452 0,13379393 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,09820452 0,13371821 ! response to ethanol GO:0045471 46 23 0,000 0,09820452 0,13364258 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09820452 0,13356703 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,09820452 0,13349157 ! peroxisome organization GO:0007031 37 23 0,000 0,09820452 0,13341619 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09820452 0,1333409 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09820452 0,13326569 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09820452 0,13319057 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,09820452 0,13311553 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,09820452 0,13304058 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,09820452 0,13296571 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,09820452 0,13289093 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09820452 0,13281623 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09820452 0,13274161 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09820452 0,13266708 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09820452 0,13259263 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09820452 0,13251827 ! fatty acid transport GO:0015908 44 23 0,000 0,09820452 0,13244399 ! platelet activation GO:0030168 37 23 0,000 0,09820452 0,13236979 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09820452 0,13229567 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09820452 0,13222164 ! hormone transport GO:0009914 40 23 0,000 0,09820452 0,13214769 ! cell-cell recognition GO:0009988 25 23 0,000 0,09820452 0,13207383 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09820452 0,13200004 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,09820452 0,13192634 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09820452 0,13185272 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,09820452 0,13177918 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,10224992 0,13713117 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,10224992 0,13705477 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,10224992 0,13697846 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,10224992 0,13690223 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,10224992 0,13682609 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10224992 0,13675004 ! vesicle docking GO:0048278 47 24 0,000 0,10224992 0,13667406 ! spinal cord development GO:0021510 47 24 0,000 0,10224992 0,13659818 ! vacuole organization GO:0007033 43 24 0,000 0,10224992 0,13652237 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,10224992 0,13644665 ! digestive system process GO:0022600 39 24 0,000 0,10224992 0,13637102 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,10224992 0,13629547 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,10224992 0,13622 ! regulation of behavior GO:0050795 43 24 0,000 0,10224992 0,13614461 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,10224992 0,13606931 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,10224992 0,13599409 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,10224992 0,13591896 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,10224992 0,13584391 ! membrane depolarization GO:0051899 39 24 0,000 0,10224992 0,13576894 ! pallium development GO:0021543 49 24 0,000 0,10224992 0,13569405 ! pentose metabolic process GO:0019321 35 24 0,000 0,10224992 0,13561925 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,10224992 0,13554453 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10224992 0,13546989 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10224992 0,13539533 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10224992 0,13532086 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10224992 0,13524646 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,10224992 0,13517215 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10224992 0,13509792 ! regulation of amine transport GO:0051952 40 24 0,000 0,10224992 0,13502377 ! protein tetramerization GO:0051262 52 24 0,000 0,10224992 0,13494971 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,10627731 0,14018817 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,10627731 0,14011135 ! myelination GO:0042552 45 25 0,000 0,10627731 0,14003462 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10627731 0,13995797 ! phototransduction GO:0007602 33 25 0,000 0,10627731 0,13988141 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10627731 0,13980493 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,10627731 0,13972853 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,10627731 0,13965222 ! sperm motility GO:0030317 31 25 0,000 0,10627731 0,13957599 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,10627731 0,13949985 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,10627731 0,13942378 ! receptor metabolic process GO:0043112 46 25 0,000 0,10627731 0,1393478 ! chromosome condensation GO:0030261 45 25 0,000 0,10627731 0,1392719 ! response to starvation GO:0042594 42 25 0,000 0,10627731 0,13919609 ! osteoblast differentiation GO:0001649 60 25 0,000 0,10627731 0,13912036 ! neural crest cell development GO:0014032 54 25 0,000 0,10627731 0,13904471 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10627731 0,13896914 ! negative regulation of cell development GO:0010721 73 25 0,000 0,10627731 0,13889365 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,10627731 0,13881825 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10627731 0,13874293 ! interaction with host GO:0051701 62 25 0,000 0,10627731 0,13866769 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10627731 0,13859253 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10627731 0,13851745 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,10627731 0,13844246 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10627731 0,13836754 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10627731 0,13829271 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,10627731 0,13821795 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,10627731 0,13814328 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10627731 0,13806869 ! telomere organization GO:0032200 43 25 0,000 0,10627731 0,13799418 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10627731 0,13791975 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,10627731 0,1378454 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,11028677 0,14296873 ! embryonic pattern specification GO:0009880 44 26 0,000 0,11028677 0,14289174 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,11028677 0,14281484 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,11028677 0,14273801 ! initiation of viral infection GO:0019059 57 26 0,000 0,11028677 0,14266127 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,11028677 0,14258462 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,11028677 0,14250804 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,11028677 0,14243155 ! molting cycle process GO:0022404 50 26 0,000 0,11028677 0,14235513 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,11028677 0,1422788 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,11028677 0,14220256 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,11028677 0,14212639 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,11028677 0,1420503 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,11028677 0,1419743 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,11028677 0,14189838 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,11028677 0,14182254 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,11028677 0,14174678 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,11028677 0,1416711 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,11028677 0,1415955 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,11028677 0,14151998 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,11028677 0,14144455 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,11028677 0,14136919 ! blastocyst development GO:0001824 49 26 0,000 0,11028677 0,14129391 ! leukocyte proliferation GO:0070661 52 26 0,000 0,11028677 0,14121872 GO:0032943|mononuclear cell proliferation, ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,11028677 0,1411436 ! neuron fate commitment GO:0048663 48 27 0,000 0,11427837 0,14617425 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,11427837 0,14609658 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,11427837 0,14601899 ! iron ion transport GO:0006826 59 27 0,000 0,11427837 0,14594149 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,11427837 0,14586406 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,11427837 0,14578672 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,11427837 0,14570947 ! fat cell differentiation GO:0045444 50 27 0,000 0,11427837 0,14563229 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,11427837 0,14555519 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,11427837 0,14547818 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,11427837 0,14540125 ! autophagy GO:0006914 41 27 0,000 0,11427837 0,1453244 ! male gonad development GO:0008584 44 27 0,000 0,11427837 0,14524763 ! response to toxin GO:0009636 47 27 0,000 0,11427837 0,14517094 ! primary neural tube formation GO:0014020 51 27 0,000 0,11427837 0,14509433 ! base-excision repair GO:0006284 41 27 0,000 0,11427837 0,14501781 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,11427837 0,14494136 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,11427837 0,144865 ! glutathione metabolic process GO:0006749 39 27 0,000 0,11427837 0,14478871 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,11427837 0,14471251 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,11427837 0,14463638 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,11427837 0,14456034 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,11427837 0,14448437 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,1182522 0,14943004 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,1182522 0,14935159 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,1182522 0,14927324 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,1182522 0,14919496 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,1182522 0,14911676 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,1182522 0,14903865 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,1182522 0,14896062 ! synaptogenesis GO:0007416 42 28 0,000 0,1182522 0,14888267 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,1182522 0,14880481 ! lipid oxidation GO:0034440 43 28 0,000 0,1182522 0,14872702 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,1182522 0,14864931 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,1182522 0,14857169 ! translational initiation GO:0006413 65 29 0,000 0,12220833 0,15346202 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,12220833 0,15338197 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,12220833 0,153302 ! regulation of pH GO:0006885 43 29 0,000 0,12220833 0,15322211 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,12220833 0,15314231 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,12220833 0,15306259 ! catechol metabolic process GO:0009712 54 29 0,000 0,12220833 0,15298295 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,12220833 0,1529034 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,12220833 0,15282393 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,12220833 0,15274454 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,12220833 0,15266523 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,12220833 0,15258601 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,12220833 0,15250686 ! cell fate determination GO:0001709 60 29 0,000 0,12220833 0,1524278 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,12220833 0,15234883 ! detection of light stimulus GO:0009583 38 29 0,000 0,12220833 0,15226993 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,12220833 0,15219111 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,12220833 0,15211238 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,12220833 0,15203373 ! tissue homeostasis GO:0001894 48 29 0,000 0,12220833 0,15195516 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,12220833 0,15187667 ! phenol metabolic process GO:0018958 55 30 0,000 0,12614684 0,15669039 ! zinc ion transport GO:0006829 45 30 0,000 0,12614684 0,15660954 ! membrane docking GO:0022406 61 30 0,000 0,12614684 0,15652877 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,12614684 0,15644809 ! cell junction assembly GO:0034329 78 30 0,000 0,12614684 0,15636748 ! regulation of innate immune response GO:0045088 51 30 0,000 0,12614684 0,15628697 ! acute-phase response GO:0006953 49 30 0,000 0,12614684 0,15620653 ! myofibril assembly GO:0030239 47 30 0,000 0,12614684 0,15612618 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,12614684 0,15604591 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,12614684 0,15596572 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,12614684 0,15588561 ! phospholipid transport GO:0015914 51 30 0,000 0,12614684 0,15580559 ! ensheathment of neurons GO:0007272 57 30 0,000 0,12614684 0,15572565 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 51 30 0,000 0,12614684 0,15564579 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,12614684 0,15556601 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,12614684 0,15548631 ! eye morphogenesis GO:0048592 60 30 0,000 0,12614684 0,1554067 ! regulation of B cell activation GO:0050864 50 30 0,000 0,12614684 0,15532717 ! response to heat GO:0009408 50 30 0,000 0,12614684 0,15524772 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,1300678 0,15999138 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,1300678 0,15990963 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,1300678 0,15982796 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,1300678 0,15974637 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,1300678 0,15966487 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,1300678 0,15958345 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,1300678 0,15950211 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,1300678 0,15942085 ! ovulation cycle process GO:0022602 49 31 0,000 0,1300678 0,15933968 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,1300678 0,15925859 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,1300678 0,15917759 ! peptide transport GO:0015833 55 31 0,000 0,1300678 0,15909666 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,1300678 0,15901582 ! iron ion homeostasis GO:0055072 54 31 0,000 0,1300678 0,15893506 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,1300678 0,15885438 ! mesoderm formation GO:0001707 69 31 0,000 0,1300678 0,15877379 ! natural killer cell activation GO:0030101 45 31 0,000 0,1300678 0,15869327 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,1300678 0,15861284 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,1300678 0,15853249 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,1300678 0,15845222 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,1300678 0,15837203 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,13397131 0,16304247 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,13397131 0,16296005 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,13397131 0,1628777 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,13397131 0,16279544 ! cholesterol transport GO:0030301 56 32 0,000 0,13397131 0,16271326 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,13397131 0,16263117 ! spliceosome assembly GO:0000245 67 32 0,000 0,13397131 0,16254915 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,13397131 0,16246722 ! metanephros development GO:0001656 74 32 0,000 0,13397131 0,16238538 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,13397131 0,16230361 ! response to ionizing radiation GO:0010212 65 32 0,000 0,13397131 0,16222193 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,13397131 0,16214033 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,13397131 0,16205881 ! muscle cell development GO:0055001 49 32 0,000 0,13397131 0,16197737 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,13397131 0,16189602 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,13397131 0,16181474 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,13397131 0,16173355 ! ovulation cycle GO:0042698 51 32 0,000 0,13397131 0,16165244 ! peripheral nervous system development GO:0007422 64 32 0,000 0,13397131 0,16157141 ! BMP signaling pathway GO:0030509 64 32 0,000 0,13397131 0,16149047 ! hindbrain development GO:0030902 61 32 0,000 0,13397131 0,1614096 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,13397131 0,16132881 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,13397131 0,16124811 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,13397131 0,16116748 ! gene silencing GO:0016458 65 32 0,000 0,13397131 0,16108694 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,13785743 0,16567681 ! post-embryonic development GO:0009791 69 33 0,000 0,13785743 0,16559409 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,13785743 0,16551146 ! protein targeting to membrane GO:0006612 68 33 0,000 0,13785743 0,16542891 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,13785743 0,16534645 ! ceramide metabolic process GO:0006672 64 33 0,000 0,13785743 0,16526406 ! formation of primary germ layer GO:0001704 72 33 0,000 0,13785743 0,16518176 ! sterol transport GO:0015918 57 33 0,000 0,13785743 0,16509954 ! adult locomotory behavior GO:0008344 59 33 0,000 0,13785743 0,1650174 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,13785743 0,16493534 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,13785743 0,16485337 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,14172624 0,16939559 ! glial cell differentiation GO:0010001 63 34 0,000 0,14172624 0,16931148 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,14172624 0,16922746 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,14172624 0,16914351 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,14172624 0,16905966 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,14172624 0,16897588 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,14172624 0,16889219 ! mismatch repair GO:0006298 46 34 0,000 0,14172624 0,16880858 ! spermatid development GO:0007286 63 34 0,000 0,14172624 0,16872505 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,14172624 0,1686416 ! placenta development GO:0001890 53 34 0,000 0,14172624 0,16855824 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,14172624 0,16847496 ! regulation of muscle development GO:0048634 70 35 0,000 0,14557781 0,17296801 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,14557781 0,17288263 ! negative regulation of secretion GO:0051048 63 35 0,000 0,14557781 0,17279734 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,14557781 0,17271214 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,14557781 0,17262702 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,14557781 0,17254198 ! odontogenesis GO:0042476 66 35 0,000 0,14557781 0,17245702 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,14557781 0,17237215 ! female gonad development GO:0008585 58 35 0,000 0,14557781 0,17228737 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,14557781 0,17220266 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,14557781 0,17211804 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,14557781 0,17203351 ! cytokine production GO:0001816 59 35 0,000 0,14557781 0,17194905 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,14557781 0,17186468 ! neural tube formation GO:0001841 67 35 0,000 0,14557781 0,17178039 ! vesicle localization GO:0051648 64 35 0,000 0,14557781 0,17169618 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,14941223 0,1761322 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,14941223 0,17604595 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,14941223 0,17595978 ! cell junction organization GO:0034330 86 36 0,000 0,14941223 0,17587369 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,14941223 0,17578769 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,14941223 0,17570177 ! positive regulation of cell development GO:0010720 80 36 0,000 0,14941223 0,17561594 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,14941223 0,17553019 ! regulation of proteolysis GO:0030162 72 36 0,000 0,14941223 0,17544452 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,14941223 0,17535894 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,14941223 0,17527344 ! aerobic respiration GO:0009060 55 36 0,000 0,14941223 0,17518803 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,14941223 0,17510269 ! embryonic organ development GO:0048568 57 36 0,000 0,14941223 0,17501744 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,14941223 0,17493228 ! RNA export from nucleus GO:0006405 56 37 0,000 0,15322957 0,17931437 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,15322957 0,1792272 ! actomyosin structure organization GO:0031032 62 37 0,000 0,15322957 0,17914011 ! organic anion transport GO:0015711 68 37 0,000 0,15322957 0,17905311 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,15322957 0,17896619 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,15322957 0,17887935 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,15322957 0,1787926 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,15322957 0,17870594 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,15322957 0,17861935 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,15322957 0,17853285 ! pigment metabolic process GO:0042440 80 37 0,000 0,15322957 0,17844644 ! spermatid differentiation GO:0048515 66 37 0,000 0,15322957 0,17836011 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,15322957 0,17827386 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,1570299 0,18260703 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,1570299 0,18251881 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,1570299 0,18243068 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,1570299 0,18234264 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,1570299 0,18225468 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,1570299 0,1821668 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,1570299 0,18207901 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,1570299 0,1819913 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,1570299 0,18190368 ! lipid homeostasis GO:0055088 67 38 0,000 0,1570299 0,18181614 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,1570299 0,18172869 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,1570299 0,18164132 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,1570299 0,18155403 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,1570299 0,18146683 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,1570299 0,18137971 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,1570299 0,18129268 ! mRNA catabolic process GO:0006402 71 39 0,000 0,1608133 0,18557161 ! learning GO:0007612 77 39 0,000 0,1608133 0,18548265 ! ear morphogenesis GO:0042471 60 39 0,000 0,1608133 0,18539378 ! organic ether metabolic process GO:0018904 55 39 0,000 0,1608133 0,18530499 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,1608133 0,18521628 ! ion transmembrane transport GO:0034220 66 39 0,000 0,1608133 0,18512766 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,1608133 0,18503913 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,1608133 0,18495067 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,1608133 0,18486231 ! RNA modification GO:0009451 57 39 0,000 0,1608133 0,18477403 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,16457985 0,18901151 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,16457985 0,18892134 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,16457985 0,18883125 ! feeding behavior GO:0007631 59 40 0,000 0,16457985 0,18874124 ! negative regulation of binding GO:0051100 72 40 0,000 0,16457985 0,18865132 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,16457985 0,18856149 ! mesenchymal cell development GO:0014031 87 40 0,000 0,16457985 0,18847174 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 0,000 0,16457985 0,18838208 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,16832962 0,19258253 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,16832962 0,192491 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,16832962 0,19239955 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,16832962 0,1923082 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,16832962 0,19221693 ! T cell differentiation GO:0030217 81 41 0,000 0,16832962 0,19212574 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,16832962 0,19203464 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,16832962 0,19194363 ! female gamete generation GO:0007292 61 41 0,000 0,16832962 0,19185271 ! polyol metabolic process GO:0019751 66 41 0,000 0,16832962 0,19176187 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,16832962 0,19167111 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,17206268 0,19582914 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,17206268 0,19573655 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,17206268 0,19564405 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,17206268 0,19555163 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,17206268 0,1954593 ! neuron migration GO:0001764 79 42 0,000 0,17206268 0,19536706 ! regulation of protein secretion GO:0050708 71 42 0,000 0,17206268 0,19527491 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,1757791 0,19939864 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,1757791 0,19930468 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,1757791 0,1992108 ! glucose transport GO:0015758 65 43 0,000 0,1757791 0,19911701 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,1757791 0,19902331 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,1757791 0,19892969 ! neural tube development GO:0021915 77 43 0,000 0,1757791 0,19883617 ! striated muscle contraction GO:0006941 77 43 0,000 0,1757791 0,19874273 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,1757791 0,19864938 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,17947897 0,2027354 ! hexose transport GO:0008645 67 44 0,000 0,17947897 0,20264027 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,17947897 0,20254522 ! double-strand break repair GO:0006302 81 44 0,000 0,17947897 0,20245026 ! biopolymer methylation GO:0043414 84 44 0,000 0,17947897 0,20235539 ! B cell differentiation GO:0030183 107 44 0,000 0,17947897 0,20226061 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,17947897 0,20216592 ! developmental growth GO:0048589 82 44 0,000 0,17947897 0,20207132 ! maintenance of location in cell GO:0051651 97 44 0,000 0,17947897 0,2019768 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,18316235 0,20602554 ! glycolysis GO:0006096 65 45 0,000 0,18316235 0,20592926 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,18316235 0,20583308 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,18316235 0,20573699 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,18316235 0,20564098 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,18316235 0,20554507 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,18316235 0,20544924 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,18316235 0,20535351 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,18316235 0,20525786 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,18316235 0,2051623 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,18682932 0,20917234 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,18682932 0,20907505 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,18682932 0,20897785 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,18682932 0,20888074 ! pigmentation GO:0043473 100 46 0,000 0,18682932 0,20878372 ! response to insulin stimulus GO:0032868 95 46 0,000 0,18682932 0,20868679 ! positive regulation of defense response GO:0031349 76 47 0,000 0,19047995 0,21266578 ! response to calcium ion GO:0051592 81 47 0,000 0,19047995 0,21256714 ! endosome transport GO:0016197 108 47 0,000 0,19047995 0,2124686 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,19047995 0,21237014 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,19047995 0,21227177 ! JNK cascade GO:0007254 91 47 0,000 0,19047995 0,2121735 ! methylation GO:0032259 90 47 0,000 0,19047995 0,21207532 ! Notch signaling pathway GO:0007219 96 48 0,000 0,19411431 0,21602175 ! cellular component disassembly GO:0022411 86 48 0,000 0,19411431 0,21592188 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,19411431 0,2158221 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,19411431 0,21572242 ! activation of caspase activity GO:0006919 84 48 0,000 0,19411431 0,21562282 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,19411431 0,21552332 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,19411431 0,21542391 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,19411431 0,21532459 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,19411431 0,21522536 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,19773247 0,21913604 ! regulation of action potential GO:0001508 95 49 0,000 0,19773247 0,21903514 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,19773247 0,21893435 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,19773247 0,21883364 ! regulation of ion transport GO:0043269 77 49 0,000 0,19773247 0,21873303 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,19773247 0,21863251 ! peptide metabolic process GO:0006518 76 49 0,000 0,19773247 0,21853208 ! response to temperature stimulus GO:0009266 76 49 0,000 0,19773247 0,21843174 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,19773247 0,2183315 ! endocrine system development GO:0035270 104 49 0,000 0,19773247 0,21823135 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,19773247 0,21813129 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,19773247 0,21803132 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,19773247 0,21793144 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,19773247 0,21783165 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,20133451 0,22169833 ! neuromuscular process GO:0050905 99 50 0,000 0,20133451 0,22159691 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,20133451 0,22149558 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,20133451 0,22139435 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,20133451 0,22129321 ! viral infectious cycle GO:0019058 99 51 0,000 0,2049205 0,22513184 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,2049205 0,22502908 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,2049205 0,22492642 ! excretion GO:0007588 83 51 0,000 0,2049205 0,22482386 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,2049205 0,22472139 ! chromatin remodeling GO:0006338 109 51 0,000 0,2049205 0,22461901 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,2049205 0,22451672 ! vesicle organization GO:0016050 107 51 0,000 0,2049205 0,22441453 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,2049205 0,22431243 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,2049205 0,22421042 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,2049205 0,22410851 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,2084905 0,2279092 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,2084905 0,2278057 ! membrane fusion GO:0006944 110 52 0,000 0,2084905 0,22770229 ! positive regulation of growth GO:0045927 90 52 0,000 0,2084905 0,22759898 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,2084905 0,22749576 ! synapse organization GO:0050808 85 52 0,000 0,2084905 0,22739263 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,2120446 0,23116416 ! RNA catabolic process GO:0006401 93 53 0,000 0,2120446 0,23105946 ! regulation of translational initiation GO:0006446 82 53 0,000 0,2120446 0,23095487 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,2120446 0,23085036 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,2120446 0,23074595 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,2120446 0,23064164 ! cell maturation GO:0048469 100 53 0,000 0,2120446 0,23053741 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,2120446 0,23043329 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,2120446 0,23032925 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,21558285 0,23406694 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,21558285 0,23396136 ! cell recognition GO:0008037 85 54 0,000 0,21558285 0,23385587 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,21558285 0,23375049 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,21558285 0,23364519 ! chloride transport GO:0006821 90 55 0,000 0,21910533 0,23735588 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,21910533 0,23724906 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,21910533 0,23714234 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,21910533 0,23703571 ! aging GO:0007568 103 55 0,000 0,21910533 0,23692918 ! gastrulation GO:0007369 112 55 0,000 0,21910533 0,23682274 ! heart morphogenesis GO:0003007 97 55 0,000 0,21910533 0,2367164 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,21910533 0,23661015 ! RNA elongation GO:0006354 79 55 0,000 0,21910533 0,236504 ! nuclear export GO:0051168 97 55 0,000 0,21910533 0,23639794 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,21910533 0,23629198 ! regulation of actin filament length GO:0030832 105 56 0,000 0,22261211 0,23996628 ! sensory perception of smell GO:0007608 80 56 0,000 0,22261211 0,23985881 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,22261211 0,23975144 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,22261211 0,23964417 ! regulation of DNA replication GO:0006275 101 56 0,000 0,22261211 0,239537 ! proton transport GO:0015992 94 56 0,000 0,22261211 0,23942992 ! lipid modification GO:0030258 97 57 0,000 0,22610325 0,24307615 ! maintenance of location GO:0051235 118 57 0,000 0,22610325 0,24296759 ! hydrogen transport GO:0006818 97 58 0,000 0,22957884 0,24659227 ! regulation of endocytosis GO:0030100 91 58 0,000 0,22957884 0,24648223 ! adult behavior GO:0030534 99 58 0,000 0,22957884 0,24637229 ! positive regulation of secretion GO:0051047 95 59 0,000 0,23303893 0,24997399 ! regulation of cellular component size GO:0032535 109 59 0,000 0,23303893 0,24986259 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,23303893 0,2497513 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,23303893 0,2496401 ! DNA catabolic process GO:0006308 86 59 0,000 0,23303893 0,249529 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,23648359 0,25310477 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,23648359 0,25299223 ! regulation of heart contraction GO:0008016 110 60 0,000 0,23648359 0,25287979 ! camera-type eye development GO:0043010 116 60 0,000 0,23648359 0,25276745 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,23648359 0,25265521 ! kidney development GO:0001822 122 60 0,000 0,23648359 0,25254306 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,2399129 0,25609159 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,2399129 0,25597802 ! mesoderm development GO:0007498 119 61 0,000 0,2399129 0,25586456 ! tRNA processing GO:0008033 89 61 0,000 0,2399129 0,25575119 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,2399129 0,25563793 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,2399129 0,25552476 ! viral reproductive process GO:0022415 126 62 0,000 0,24332692 0,25904627 ! gonad development GO:0008406 98 62 0,000 0,24332692 0,2589317 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,24672572 0,26243239 ! detection of external stimulus GO:0009581 91 63 0,000 0,24672572 0,26231643 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,24672572 0,26220056 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,25010936 0,26567908 ! cell redox homeostasis GO:0045454 102 64 0,000 0,25010936 0,26556184 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,25010936 0,26544469 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,25010936 0,26532766 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,25010936 0,26521072 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,25347792 0,26866426 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,25347792 0,26854596 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,25347792 0,26842776 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,25347792 0,26830967 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,25347792 0,26819168 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,25683145 0,27162043 ! actin filament organization GO:0007015 148 66 0,000 0,25683145 0,27150109 ! developmental maturation GO:0021700 116 66 0,000 0,25683145 0,27138185 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,26017004 0,2747889 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,26017004 0,27466832 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,26017004 0,27454786 ! activation of MAPK activity GO:0000187 115 67 0,000 0,26017004 0,27442749 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,26017004 0,27430723 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,26017004 0,27418708 ! hexose catabolic process GO:0019320 104 67 0,000 0,26017004 0,27406704 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,26017004 0,27394709 ! adaptive immune response GO:0002250 119 67 0,000 0,26017004 0,27382726 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,26017004 0,27370752 ! amino acid transport GO:0006865 125 68 0,000 0,26349373 0,27708301 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,26349373 0,27696196 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,26349373 0,27684101 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,26349373 0,27672017 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,26349373 0,27659944 ! viral reproduction GO:0016032 134 68 0,000 0,26349373 0,27647881 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,26349373 0,27635829 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,26349373 0,27623787 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,26680261 0,27958496 ! negative regulation of cell size GO:0045792 134 69 0,000 0,26680261 0,27946324 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,26680261 0,27934163 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,26680261 0,27922013 ! urogenital system development GO:0001655 137 69 0,000 0,26680261 0,27909873 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,26680261 0,27897743 ! antigen processing and presentation GO:0019882 104 69 0,000 0,26680261 0,27885624 ! appendage morphogenesis GO:0035107 135 70 0,000 0,27009672 0,2821766 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 0,000 0,27337615 0,28547874 ! appendage development GO:0048736 136 71 0,000 0,27337615 0,28535489 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,27337615 0,28523114 ! B cell activation GO:0042113 160 71 0,000 0,27337615 0,28510751 ! regulation of immune effector process GO:0002697 137 71 0,000 0,27337615 0,28498398 ! acute inflammatory response GO:0002526 113 72 0,000 0,27664095 0,28826251 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,27664095 0,28813772 ! carbohydrate transport GO:0008643 110 72 0,000 0,27664095 0,28801304 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,27664095 0,28788846 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,27664095 0,287764 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,27664095 0,28763964 ! learning or memory GO:0007611 147 73 0,000 0,27989119 0,29089339 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,27989119 0,29076779 ! fertilization GO:0009566 90 73 0,000 0,27989119 0,2906423 ! transition metal ion transport GO:0000041 126 74 0,000 0,28312694 0,2938755 ! neurotransmitter transport GO:0006836 123 74 0,000 0,28312694 0,29374877 ! exocytosis GO:0006887 133 74 0,000 0,28312694 0,29362216 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,28312694 0,29349565 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,28312694 0,29336925 ! eye development GO:0001654 143 74 0,000 0,28312694 0,29324297 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,28634825 0,29645176 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,28634825 0,29632425 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,28634825 0,29619685 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,28634825 0,29606957 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,28955519 0,29925678 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,28955519 0,29912829 ! defense response to bacterium GO:0042742 89 76 0,000 0,28955519 0,29899991 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,28955519 0,29887164 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,28955519 0,29874348 ! regulation of catabolic process GO:0009894 161 76 0,000 0,28955519 0,29861543 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,29274783 0,30177861 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,29274783 0,30164937 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,29274783 0,30152024 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,29274783 0,30139122 ! blood coagulation GO:0007596 146 78 0,000 0,29592623 0,30453315 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,29592623 0,30440295 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,29592623 0,30427286 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,29909044 0,30739496 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,29909044 0,30726371 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,29909044 0,30713257 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,29909044 0,30700154 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,29909044 0,30687062 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,30224055 0,30997049 ! response to metal ion GO:0010038 140 80 0,000 0,30224055 0,30983841 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,30224055 0,30970646 ! inorganic anion transport GO:0015698 138 80 0,000 0,30224055 0,30957461 ! T cell activation GO:0042110 168 81 0,000 0,3053766 0,31265366 ! digestion GO:0007586 112 81 0,000 0,3053766 0,31252067 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,3053766 0,31238779 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,3053766 0,31225503 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,30849866 0,31531341 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,30849866 0,31517952 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,30849866 0,31504574 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,30849866 0,31491208 ! regulation of lyase activity GO:0051339 160 83 0,000 0,31160679 0,31794993 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,31470105 0,32097106 ! hemostasis GO:0007599 158 84 0,000 0,31470105 0,32083505 ! negative regulation of transport GO:0051051 153 84 0,000 0,31470105 0,32069916 ! negative regulation of growth GO:0045926 155 84 0,000 0,31470105 0,32056339 ! regulation of ligase activity GO:0051340 142 84 0,000 0,31470105 0,32042773 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,31470105 0,32029218 ! response to unfolded protein GO:0006986 131 85 0,000 0,31778151 0,32329061 ! nucleosome assembly GO:0006334 122 85 0,000 0,31778151 0,32315397 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,31778151 0,32301745 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,31778151 0,32288104 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 0,000 0,32084822 0,32585935 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,32084822 0,32572186 ! chromatin assembly GO:0031497 124 86 0,000 0,32084822 0,32558448 ! tube morphogenesis GO:0035239 176 86 0,000 0,32084822 0,32544722 ! mitochondrion organization GO:0007005 148 86 0,000 0,32084822 0,32531008 ! alcohol catabolic process GO:0046164 130 86 0,000 0,32084822 0,32517305 ! amine transport GO:0015837 155 86 0,000 0,32084822 0,32503613 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,32390125 0,32799091 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,32694065 0,33092941 ! regulation of neurological system process GO:0031644 148 88 0,000 0,32694065 0,33079025 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,32694065 0,3306512 ! cellular defense response GO:0006968 114 89 0,000 0,32996649 0,33357117 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,32996649 0,33343107 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,33297883 0,33633378 ! sex differentiation GO:0007548 145 90 0,000 0,33297883 0,33619264 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,33297883 0,33605162 ! sterol metabolic process GO:0016125 152 91 0,000 0,33597773 0,33893602 ! response to protein stimulus GO:0051789 149 91 0,000 0,33597773 0,33879397 ! regulation of defense response GO:0031347 149 92 0,000 0,33896324 0,34166131 ! nucleosome organization GO:0034728 138 92 0,000 0,33896324 0,34151824 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,33896324 0,34137529 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,34193543 0,34422454 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,34193543 0,34408057 ! regulation of membrane potential GO:0042391 164 93 0,000 0,34193543 0,34393672 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,34193543 0,343793 ! female pregnancy GO:0007565 164 94 0,000 0,34489435 0,34662315 ! transcription initiation GO:0006352 153 94 0,000 0,34489435 0,34647842 ! regulation of T cell activation GO:0050863 158 94 0,000 0,34489435 0,34633381 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,34784007 0,3491461 ! leukocyte differentiation GO:0002521 202 96 0,000 0,35077264 0,35194286 ! mRNA transport GO:0051028 169 96 0,000 0,35077264 0,35179615 ! positive regulation of immune response GO:0050778 156 96 0,000 0,35077264 0,35164957 ! detection of stimulus GO:0051606 151 96 0,000 0,35077264 0,35150311 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,35369212 0,35428112 ! hormone metabolic process GO:0042445 157 97 0,000 0,35369212 0,35413368 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,35949204 0,35979112 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,35949204 0,35964152 ! cell cycle arrest GO:0007050 213 100 0,000 0,3623726 0,3623726