pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1130-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! epithelial to mesenchymal transition GO:0001837 28 15 4,000 1,504E-09 3,618E-06 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 3,193E-08 3,841E-05 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 2,051E-07 1,645E-04 ! mesenchymal cell development GO:0014031 87 40 4,000 3,07E-07 1,847E-04 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! response to insulin stimulus GO:0032868 95 46 4,000 6,288E-07 3,026E-04 ! positive regulation of ossification GO:0045778 47 20 3,000 6,983E-07 2,8E-04 ! salivary gland morphogenesis GO:0007435 13 6 2,000 8,652E-07 2,974E-04 ! positive regulation of bone remodeling GO:0046852 51 22 3,000 1,048E-06 3,153E-04 GO:0034105|positive regulation of tissue remodeling, ! regulation of DNA metabolic process GO:0051052 178 97 5,000 1,327E-06 3,548E-04 ! protein import into nucleus, translocation GO:0000060 46 24 3,000 1,515E-06 3,644E-04 ! response to endoplasmic reticulum stress GO:0034976 43 25 3,000 1,798E-06 3,933E-04 ! positive regulation of cell migration GO:0030335 126 57 4,000 1,862E-06 3,733E-04 ! ER overload response GO:0006983 12 8 2,000 2,41E-06 4,461E-04 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 2,000 2,41E-06 4,142E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 2,41E-06 3,866E-04 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 2,616E-06 3,934E-04 ! ER-nuclear signaling pathway GO:0006984 48 28 3,000 2,887E-06 4,086E-04 ! positive regulation of cell motion GO:0051272 146 64 4,000 3,325E-06 4,444E-04 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 2,000 3,606E-06 4,566E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 3,606E-06 4,338E-04 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 2,000 3,606E-06 4,131E-04 ! positive regulation of B cell proliferation GO:0030890 16 10 2,000 5,138E-06 5,619E-04 ! SMAD protein nuclear translocation GO:0007184 20 10 2,000 5,138E-06 5,375E-04 ! salivary gland development GO:0007431 27 10 2,000 5,138E-06 5,151E-04 ! regulation of B cell proliferation GO:0030888 20 12 2,000 9,371E-06 9,018E-04 ! gland morphogenesis GO:0022612 29 12 2,000 9,371E-06 8,672E-04 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 4,000 9,42E-06 8,395E-04 ! protein import into nucleus GO:0006606 158 80 4,000 1,002E-05 8,61E-04 ! nuclear import GO:0051170 161 81 4,000 1,065E-05 8,835E-04 ! mammary gland development GO:0030879 86 39 3,000 1,125E-05 9,026E-04 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 1,131E-05 8,777E-04 ! exocrine system development GO:0035272 32 13 2,000 1,215E-05 9,136E-04 ! negative regulation of growth GO:0045926 155 84 4,000 1,272E-05 9,277E-04 ! tube morphogenesis GO:0035239 176 86 4,000 1,427E-05 1,01E-03 ! protein localization in nucleus GO:0034504 176 87 4,000 1,51E-05 1,038E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 1,542E-05 1,031E-03 GO:0060675|ureteric bud morphogenesis, ! positive regulation of bone mineralization GO:0030501 29 14 2,000 1,542E-05 1,003E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 1,542E-05 9,766E-04 ! gland development GO:0048732 206 88 4,000 1,597E-05 9,849E-04 ! positive regulation of biomineral formation GO:0070169 30 15 2,000 1,923E-05 1,157E-03 ! dopamine metabolic process GO:0042417 35 15 2,000 1,923E-05 1,129E-03 ! branching morphogenesis of a tube GO:0048754 97 45 3,000 2,005E-05 1,149E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 2,005E-05 1,122E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 2,088E-05 1,142E-03 ! regulation of gene-specific transcription GO:0032583 96 46 3,000 2,19E-05 1,171E-03 ! negative regulation of immune response GO:0050777 35 16 2,000 2,361E-05 1,235E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 2,361E-05 1,208E-03 ! cell cycle arrest GO:0007050 213 100 4,000 2,966E-05 1,487E-03 ! regulation of ossification GO:0030278 117 50 3,000 3,058E-05 1,501E-03 ! epithelial tube morphogenesis GO:0060562 98 51 3,000 3,309E-05 1,592E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 2,000 3,422E-05 1,614E-03 ! morphogenesis of a branching structure GO:0001763 111 52 3,000 3,575E-05 1,654E-03 ! response to UV GO:0009411 104 53 3,000 3,856E-05 1,751E-03 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 2,000 4,053E-05 1,806E-03 ! heart morphogenesis GO:0003007 97 55 3,000 4,467E-05 1,954E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 4,756E-05 2,043E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 4,756E-05 2,008E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 4,798E-05 1,99E-03 ! regulation of bone remodeling GO:0046850 137 57 3,000 5,146E-05 2,098E-03 ! regulation of tissue remodeling GO:0034103 140 58 3,000 5,512E-05 2,21E-03 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 2,000 5,535E-05 2,183E-03 ! skeletal system morphogenesis GO:0048705 105 59 3,000 5,896E-05 2,288E-03 ! ureteric bud development GO:0001657 43 22 2,000 6,392E-05 2,441E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 6,392E-05 2,403E-03 ! positive regulation of B cell activation GO:0050871 38 22 2,000 6,392E-05 2,366E-03 ! regulation of bone mineralization GO:0030500 49 23 2,000 7,332E-05 2,673E-03 ! regulation of alpha-beta T cell activation GO:0046634 42 24 2,000 8,358E-05 3,001E-03 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 8,358E-05 2,957E-03 ! protein tetramerization GO:0051262 52 24 2,000 8,358E-05 2,914E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 9,473E-05 3,256E-03 ! regulation of biomineral formation GO:0070167 51 25 2,000 9,473E-05 3,21E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 9,716E-05 3,247E-03 ! activation of MAPK activity GO:0000187 115 67 3,000 9,716E-05 3,202E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 1,068E-04 3,473E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 1,068E-04 3,426E-03 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of MAPKKK cascade GO:0043410 47 26 2,000 1,068E-04 3,381E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 1,09E-04 3,406E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 1,198E-04 3,697E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,242E-04 3,782E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,242E-04 3,735E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 1,242E-04 3,689E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,242E-04 3,644E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,242E-04 3,6E-03 ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 1,242E-04 3,557E-03 GO:0051489|regulation of filopodium assembly, ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 1,242E-04 3,515E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! muscle cell proliferation GO:0033002 11 5 1,000 1,242E-04 3,474E-03 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 1,000 1,242E-04 3,434E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 1,242E-04 3,395E-03 GO:0042634|regulation of hair cycle, ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 1,000 1,242E-04 3,357E-03 ! glial cell migration GO:0008347 11 5 1,000 1,242E-04 3,32E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 1,242E-04 3,283E-03 GO:0051930|regulation of sensory perception of pain, ! release of sequestered calcium ion into cytosol GO:0051209 11 5 1,000 1,242E-04 3,248E-03 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! stem cell division GO:0017145 11 5 1,000 1,242E-04 3,213E-03 GO:0048103|somatic stem cell division, ! regulation of caspase activity GO:0043281 122 72 3,000 1,286E-04 3,293E-03 ! positive regulation of T cell differentiation GO:0045582 42 28 2,000 1,339E-04 3,391E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 1,339E-04 3,355E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 1,431E-04 3,549E-03 ! catechol metabolic process GO:0009712 54 29 2,000 1,489E-04 3,657E-03 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,489E-04 3,62E-03 ! phenol metabolic process GO:0018958 55 30 2,000 1,651E-04 3,972E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 1,651E-04 3,932E-03 ! positive regulation of lymphocyte activation GO:0051251 127 77 3,000 1,669E-04 3,938E-03 ! protein oligomerization GO:0051259 139 78 3,000 1,755E-04 4,099E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 1,843E-04 4,265E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 1,858E-04 4,258E-03 ! thymic T cell selection GO:0045061 12 6 1,000 1,858E-04 4,218E-03 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 1,000 1,858E-04 4,179E-03 ! male sex determination GO:0030238 15 6 1,000 1,858E-04 4,14E-03 ! negative regulation of multicellular organism growth GO:0040015 8 6 1,000 1,858E-04 4,102E-03 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 1,858E-04 4,065E-03 GO:0043011|myeloid dendritic cell differentiation, ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,858E-04 4,028E-03 ! metanephros development GO:0001656 74 32 2,000 2,006E-04 4,31E-03 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 2,000 2,006E-04 4,272E-03 ! response to hypoxia GO:0001666 171 81 3,000 2,03E-04 4,285E-03 ! DNA damage checkpoint GO:0000077 71 33 2,000 2,201E-04 4,605E-03 ! response to oxygen levels GO:0070482 176 83 3,000 2,23E-04 4,626E-03 ! positive regulation of cell activation GO:0050867 145 85 3,000 2,444E-04 5,026E-03 GO:0002696|positive regulation of leukocyte activation, ! regulation of helicase activity GO:0051095 15 7 1,000 2,596E-04 5,293E-03 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 2,596E-04 5,248E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,596E-04 5,204E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,596E-04 5,161E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 2,596E-04 5,119E-03 ! positive regulation of isotype switching GO:0045830 15 7 1,000 2,596E-04 5,077E-03 GO:0045911|positive regulation of DNA recombination, ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,596E-04 5,036E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,596E-04 4,996E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,596E-04 4,956E-03 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 1,000 2,596E-04 4,917E-03 GO:0002714|positive regulation of B cell mediated immunity, ! response to tumor cell GO:0002347 13 7 1,000 2,596E-04 4,879E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,596E-04 4,841E-03 ! dopamine biosynthetic process GO:0042416 18 7 1,000 2,596E-04 4,804E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 2,596E-04 4,767E-03 ! embryonic skeletal system morphogenesis GO:0048704 59 35 2,000 2,627E-04 4,788E-03 ! negative regulation of hydrolase activity GO:0051346 62 35 2,000 2,627E-04 4,752E-03 ! positive regulation of cell development GO:0010720 80 36 2,000 2,858E-04 5,132E-03 ! DNA integrity checkpoint GO:0031570 75 36 2,000 2,858E-04 5,094E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 3,36E-04 5,944E-03 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 3,36E-04 5,9E-03 ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 3,36E-04 5,858E-03 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,453E-04 5,977E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 3,453E-04 5,934E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,453E-04 5,892E-03 ! positive regulation of epidermis development GO:0045684 13 8 1,000 3,453E-04 5,85E-03 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 3,453E-04 5,809E-03 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 1,000 3,453E-04 5,769E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 3,739E-04 6,205E-03 ! leukocyte differentiation GO:0002521 202 96 3,000 3,891E-04 6,413E-03 ! interphase GO:0051325 213 98 3,000 4,209E-04 6,888E-03 ! T cell differentiation GO:0030217 81 41 2,000 4,213E-04 6,848E-03 ! regulation of T cell differentiation GO:0045580 70 41 2,000 4,213E-04 6,803E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 4,429E-04 7,104E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 4,429E-04 7,057E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 4,429E-04 7,011E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 4,429E-04 6,965E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 4,429E-04 6,92E-03 ! T cell selection GO:0045058 23 9 1,000 4,429E-04 6,875E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 4,429E-04 6,831E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 4,429E-04 6,788E-03 GO:0002820|negative regulation of adaptive immune response, ! regulation of telomere maintenance GO:0032204 14 9 1,000 4,429E-04 6,745E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 4,525E-04 6,847E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 4,852E-04 7,296E-03 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 2,000 5,194E-04 7,761E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 5,524E-04 8,203E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 5,524E-04 8,153E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 5,524E-04 8,103E-03 ! positive regulation of heart contraction GO:0045823 16 10 1,000 5,524E-04 8,054E-03 ! regulation of smoothened signaling pathway GO:0008589 23 10 1,000 5,524E-04 8,006E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 5,524E-04 7,958E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 5,524E-04 7,91E-03 GO:0045685|regulation of glial cell differentiation, ! regulation of B cell differentiation GO:0045577 19 10 1,000 5,524E-04 7,864E-03 ! protein sumoylation GO:0016925 15 10 1,000 5,524E-04 7,817E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 5,524E-04 7,772E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 5,524E-04 7,726E-03 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of immune effector process GO:0002698 20 10 1,000 5,524E-04 7,682E-03 ! cell growth GO:0016049 84 45 2,000 5,55E-04 7,675E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 5,922E-04 8,142E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 5,922E-04 8,096E-03 ! pigmentation GO:0043473 100 46 2,000 5,922E-04 8,05E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 5,922E-04 8,005E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 6,713E-04 9,023E-03 ! activation of caspase activity GO:0006919 84 48 2,000 6,713E-04 8,973E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 6,713E-04 8,923E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 6,713E-04 8,874E-03 ! detection of mechanical stimulus GO:0050982 22 11 1,000 6,735E-04 8,855E-03 ! T cell proliferation GO:0042098 26 11 1,000 6,735E-04 8,807E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 6,735E-04 8,76E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 6,735E-04 8,712E-03 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 6,735E-04 8,666E-03 ! DNA methylation GO:0006306 19 11 1,000 6,735E-04 8,62E-03 GO:0006305|DNA alkylation, ! regulation of isotype switching GO:0045191 22 11 1,000 6,735E-04 8,574E-03 ! thymus development GO:0048538 27 11 1,000 6,735E-04 8,529E-03 ! cardiac cell differentiation GO:0035051 31 11 1,000 6,735E-04 8,484E-03 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 6,735E-04 8,44E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 6,735E-04 8,396E-03 ! negative regulation of immune system process GO:0002683 95 50 2,000 7,568E-04 9,386E-03 ! embryonic skeletal system development GO:0048706 85 51 2,000 8,02E-04 9,896E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 8,02E-04 9,845E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 8,064E-04 9,848E-03 ! virus-host interaction GO:0019048 29 12 1,000 8,064E-04 9,799E-03 ! regulation of cell projection assembly GO:0060491 30 12 1,000 8,064E-04 9,749E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 8,064E-04 9,701E-03 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 8,064E-04 9,652E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 8,064E-04 9,604E-03 ! focal adhesion formation GO:0048041 35 12 1,000 8,064E-04 9,557E-03 ! histone acetylation GO:0016573 26 12 1,000 8,064E-04 9,51E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 8,064E-04 9,464E-03 ! T cell homeostasis GO:0043029 25 12 1,000 8,064E-04 9,418E-03 ! positive regulation of growth GO:0045927 90 52 2,000 8,49E-04 9,868E-03 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 8,976E-04 0,01038258 ! response to X-ray GO:0010165 25 13 1,000 9,508E-04 0,01094516 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 9,508E-04 0,01089304 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 9,508E-04 0,01084142 ! regulation of epidermis development GO:0045682 19 13 1,000 9,508E-04 0,01079028 ! positive regulation of caspase activity GO:0043280 95 55 2,000 1E-03 0,0112963 GO:0010952|positive regulation of peptidase activity, ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,107E-03 0,0124421 ! regulation of S phase GO:0033261 23 14 1,000 1,107E-03 0,01238423 ! hair follicle morphogenesis GO:0031069 26 14 1,000 1,107E-03 0,0123269 ! palate development GO:0060021 31 14 1,000 1,107E-03 0,01227009 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 1,107E-03 0,01221381 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 1,107E-03 0,01215804 ! response to gamma radiation GO:0010332 28 14 1,000 1,107E-03 0,01210277 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 1,107E-03 0,01204801 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 1,11E-03 0,012026 ! regulation of intracellular transport GO:0032386 101 57 2,000 1,11E-03 0,01197207 ! positive regulation of cell size GO:0045793 27 15 1,000 1,274E-03 0,01368359 ! heterophilic cell adhesion GO:0007157 39 15 1,000 1,274E-03 0,01362277 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,274E-03 0,0135625 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,274E-03 0,01350275 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 1,274E-03 0,01344353 ! lymphocyte homeostasis GO:0002260 30 15 1,000 1,274E-03 0,01338482 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 1,288E-03 0,01347103 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 1,288E-03 0,01341271 ! kidney development GO:0001822 122 60 2,000 1,288E-03 0,0133549 ! regulation of homeostatic process GO:0032844 134 62 2,000 1,416E-03 0,01462113 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,453E-03 0,01493541 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,453E-03 0,01487185 ! bone remodeling GO:0046849 27 16 1,000 1,453E-03 0,01480883 ! regulation of neurotransmitter secretion GO:0046928 33 16 1,000 1,453E-03 0,01474635 ! startle response GO:0001964 28 16 1,000 1,453E-03 0,01468439 ! regulation of dephosphorylation GO:0035303 43 16 1,000 1,453E-03 0,01462295 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,453E-03 0,01456202 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 1,000 1,453E-03 0,0145016 ! defense response to virus GO:0051607 37 16 1,000 1,453E-03 0,01444167 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 1,623E-03 0,01606731 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of cell killing GO:0031343 32 17 1,000 1,642E-03 0,01619548 ! myoblast differentiation GO:0045445 45 17 1,000 1,642E-03 0,01612938 ! regulation of survival gene product expression GO:0045884 33 17 1,000 1,642E-03 0,01606381 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 1,642E-03 0,01599877 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 1,642E-03 0,01593426 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 1,000 1,642E-03 0,01587027 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 1,000 1,642E-03 0,01580679 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 1,642E-03 0,01574381 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 1,771E-03 0,01690502 ! positive regulation of T cell activation GO:0050870 109 67 2,000 1,771E-03 0,0168382 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,843E-03 0,01746208 ! patterning of blood vessels GO:0001569 39 18 1,000 1,843E-03 0,0173936 ! epidermis morphogenesis GO:0048730 40 18 1,000 1,843E-03 0,01732565 ! cell-substrate junction assembly GO:0007044 54 18 1,000 1,843E-03 0,01725824 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 1,843E-03 0,01719135 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 1,843E-03 0,01712497 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 1,843E-03 0,0170591 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 1,843E-03 0,01699374 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 1,843E-03 0,01692888 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,843E-03 0,01686451 ! negative regulation of kinase activity GO:0033673 131 68 2,000 1,848E-03 0,01683807 ! cell cycle checkpoint GO:0000075 137 69 2,000 1,927E-03 0,01749203 ! urogenital system development GO:0001655 137 69 2,000 1,927E-03 0,01742627 ! appendage morphogenesis GO:0035107 135 70 2,000 2,008E-03 0,01809184 GO:0035108|limb morphogenesis, ! lipid phosphorylation GO:0046834 35 19 1,000 2,056E-03 0,01845411 ! pigmentation during development GO:0048066 41 19 1,000 2,056E-03 0,01838551 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,056E-03 0,01831741 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 42 19 1,000 2,056E-03 0,01824982 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 2,056E-03 0,01818273 ! G1 phase GO:0051318 40 19 1,000 2,056E-03 0,01811612 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 2,056E-03 0,01805001 ! proximal/distal pattern formation GO:0009954 32 19 1,000 2,056E-03 0,01798437 ! appendage development GO:0048736 136 71 2,000 2,091E-03 0,01822718 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 2,091E-03 0,01816138 ! negative regulation of transferase activity GO:0051348 140 72 2,000 2,176E-03 0,01883443 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,279E-03 0,01965057 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 2,279E-03 0,01958039 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 2,279E-03 0,01951071 ! cellular response to starvation GO:0009267 33 20 1,000 2,279E-03 0,01944152 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 2,279E-03 0,01937282 ! peptidyl-serine modification GO:0018209 43 20 1,000 2,279E-03 0,01930461 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 2,279E-03 0,01923687 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 2,279E-03 0,01916961 ! lymphocyte differentiation GO:0030098 167 75 2,000 2,445E-03 0,02049741 ! regulation of cell killing GO:0031341 42 21 1,000 2,513E-03 0,02099166 ! regulation of neurotransmitter transport GO:0051588 42 21 1,000 2,513E-03 0,02091903 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 2,513E-03 0,02084689 ! cell aging GO:0007569 44 21 1,000 2,513E-03 0,02077525 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 2,513E-03 0,0207041 ! DNA modification GO:0006304 34 21 1,000 2,513E-03 0,02063344 ! collagen fibril organization GO:0030199 59 21 1,000 2,513E-03 0,02056326 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 2,513E-03 0,02049355 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,758E-03 0,02241479 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 2,758E-03 0,02233932 ! apoptotic nuclear changes GO:0030262 32 22 1,000 2,758E-03 0,02226436 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 2,758E-03 0,0221899 ! activation of protein kinase activity GO:0032147 147 79 2,000 2,834E-03 0,02273007 ! positive regulation of DNA replication GO:0045740 43 23 1,000 3,013E-03 0,02408592 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 3,013E-03 0,02400617 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 3,013E-03 0,02392694 ! leukocyte adhesion GO:0007159 50 23 1,000 3,013E-03 0,02384823 ! regulation of DNA recombination GO:0000018 48 23 1,000 3,013E-03 0,02377004 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 3,013E-03 0,02369236 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 3,013E-03 0,02361519 ! sex determination GO:0007530 47 23 1,000 3,013E-03 0,02353851 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 3,013E-03 0,02346234 ! T cell activation GO:0042110 168 81 2,000 3,042E-03 0,02361149 ! response to drug GO:0042493 143 82 2,000 3,15E-03 0,0243668 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 3,28E-03 0,02529058 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 3,28E-03 0,02520978 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 3,28E-03 0,02512949 ! lymphocyte proliferation GO:0046651 48 24 1,000 3,28E-03 0,02504972 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 3,28E-03 0,02497045 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukocyte homeostasis GO:0001776 44 24 1,000 3,28E-03 0,02489167 ! vasculogenesis GO:0001570 46 25 1,000 3,557E-03 0,02690876 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 3,557E-03 0,02682441 ! negative regulation of DNA replication GO:0008156 42 25 1,000 3,557E-03 0,02674058 ! response to starvation GO:0042594 42 25 1,000 3,557E-03 0,02665728 ! negative regulation of cell development GO:0010721 73 25 1,000 3,557E-03 0,02657449 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 3,557E-03 0,02649222 ! somitogenesis GO:0001756 43 25 1,000 3,557E-03 0,02641045 ! immunoglobulin production GO:0002377 55 25 1,000 3,557E-03 0,02632919 GO:0002440|production of molecular mediator of immune response, ! cellular response to nutrient levels GO:0031669 41 25 1,000 3,557E-03 0,02624842 ! mitochondrion organization GO:0007005 148 86 2,000 3,603E-03 0,02650748 ! regulation of protein transport GO:0051223 154 87 2,000 3,722E-03 0,02730047 GO:0070201|regulation of establishment of protein localization, ! regulation of neurological system process GO:0031644 148 88 2,000 3,843E-03 0,02810606 ! molting cycle process GO:0022404 50 26 1,000 3,844E-03 0,02802622 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 3,844E-03 0,02794155 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 3,844E-03 0,02785739 ! cellular response to oxidative stress GO:0034599 39 26 1,000 3,844E-03 0,02777374 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 3,844E-03 0,02769058 ! leukocyte proliferation GO:0070661 52 26 1,000 3,844E-03 0,02760792 GO:0032943|mononuclear cell proliferation, ! positive regulation of cell projection organization GO:0031346 58 27 1,000 4,142E-03 0,02965916 ! protein amino acid acylation GO:0043543 55 27 1,000 4,142E-03 0,02957115 ! fat cell differentiation GO:0045444 50 27 1,000 4,142E-03 0,02948366 ! mitochondrial membrane organization GO:0007006 57 27 1,000 4,142E-03 0,02939669 ! base-excision repair GO:0006284 41 27 1,000 4,142E-03 0,02931023 ! regulation of chromosome organization GO:0033044 42 27 1,000 4,142E-03 0,02922428 ! negative regulation of protein modification process GO:0031400 60 28 1,000 4,45E-03 0,03130782 ! synaptogenesis GO:0007416 42 28 1,000 4,45E-03 0,03121655 ! biogenic amine metabolic process GO:0006576 155 94 2,000 4,623E-03 0,03233459 ! regulation of T cell activation GO:0050863 158 94 2,000 4,623E-03 0,03224087 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 4,762E-03 0,03311119 ! regulation of pH GO:0006885 43 29 1,000 4,769E-03 0,03306588 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 4,769E-03 0,03297087 ! immune response-activating signal transduction GO:0002757 47 29 1,000 4,769E-03 0,03287639 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 4,769E-03 0,03278246 ! positive regulation of immune response GO:0050778 156 96 2,000 4,903E-03 0,03360636 ! regulation of protein localization GO:0032880 176 97 2,000 5,046E-03 0,03449208 ! cell junction assembly GO:0034329 78 30 1,000 5,098E-03 0,0347452 ! skeletal muscle tissue development GO:0007519 186 99 2,000 5,341E-03 0,03629987 GO:0060538|skeletal muscle organ development, ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 5,437E-03 0,03684697 ! iron ion homeostasis GO:0055072 54 31 1,000 5,437E-03 0,03674347 ! myeloid leukocyte activation GO:0002274 49 31 1,000 5,437E-03 0,03664055 ! positive regulation of immune effector process GO:0002699 67 31 1,000 5,437E-03 0,0365382 ! response to ionizing radiation GO:0010212 65 32 1,000 5,786E-03 0,03877588 ! response to mechanical stimulus GO:0009612 57 32 1,000 5,786E-03 0,03866817 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 5,786E-03 0,03856105 ! BMP signaling pathway GO:0030509 64 32 1,000 5,786E-03 0,03845453 ! positive regulation of catabolic process GO:0009896 64 32 1,000 5,786E-03 0,0383486 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 6,145E-03 0,04061668 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 6,145E-03 0,0405054 ! leukocyte chemotaxis GO:0030595 50 33 1,000 6,145E-03 0,04039473 GO:0060326|cell chemotaxis, ! adult locomotory behavior GO:0008344 59 33 1,000 6,145E-03 0,04028467 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 6,514E-03 0,04258775 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 6,514E-03 0,04247234 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 6,893E-03 0,04482115 ! odontogenesis GO:0042476 66 35 1,000 6,893E-03 0,04470034 ! neural tube formation GO:0001841 67 35 1,000 6,893E-03 0,04458017 ! cell junction organization GO:0034330 86 36 1,000 7,281E-03 0,04696754 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 7,281E-03 0,04684196 ! embryonic organ development GO:0048568 57 36 1,000 7,281E-03 0,04671704 ! tissue remodeling GO:0048771 76 37 1,000 7,68E-03 0,0491418 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 7,68E-03 0,04901145 ! glycogen metabolic process GO:0005977 61 37 1,000 7,68E-03 0,04888179 ! carbohydrate homeostasis GO:0033500 53 38 1,000 8,088E-03 0,05134281 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 1,000 8,088E-03 0,0512077 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 8,088E-03 0,0510733 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 8,088E-03 0,0509396 ! glucan metabolic process GO:0044042 62 38 1,000 8,088E-03 0,0508066 GO:0006073|cellular glucan metabolic process, ! ear morphogenesis GO:0042471 60 39 1,000 8,505E-03 0,05329049 ! segmentation GO:0035282 67 39 1,000 8,505E-03 0,05315207 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 8,505E-03 0,05301437 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 9,369E-03 0,05824581 ! gliogenesis GO:0042063 88 41 1,000 9,369E-03 0,05809569 ! regulation of T cell proliferation GO:0042129 71 41 1,000 9,369E-03 0,05794635 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 9,369E-03 0,05779777 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 9,815E-03 0,06039322 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 9,815E-03 0,06023916 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 9,815E-03 0,06008588 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,01026962 0,06271242 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,01026962 0,06255366 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01026962 0,06239569 ! glucose transport GO:0015758 65 43 1,000 0,01026962 0,06223852 ! neural tube development GO:0021915 77 43 1,000 0,01026962 0,06208215 ! hexose transport GO:0008645 67 44 1,000 0,01073391 0,06472631 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 1,000 0,01073391 0,06456449 ! biopolymer methylation GO:0043414 84 44 1,000 0,01073391 0,06440348 ! B cell differentiation GO:0030183 107 44 1,000 0,01073391 0,06424327 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,01073391 0,06408386 ! leukocyte migration GO:0050900 68 45 1,000 0,01120735 0,06674477 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01120735 0,06657996 ! response to calcium ion GO:0051592 81 47 1,000 0,01218136 0,07218808 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01218136 0,07201071 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,01218136 0,07183422 ! methylation GO:0032259 90 47 1,000 0,01218136 0,07165858 ! protein homooligomerization GO:0051260 76 47 1,000 0,01218136 0,0714838 ! mitochondrial transport GO:0006839 82 48 1,000 0,0126818 0,07423945 ! cellular component disassembly GO:0022411 86 48 1,000 0,0126818 0,07405926 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,0126818 0,07387994 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,0126818 0,07370148 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,0131911 0,0764766 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,0137092 0,07928925 ! neuromuscular process GO:0050905 99 50 1,000 0,0137092 0,07909911 ! histone modification GO:0016570 91 50 1,000 0,0137092 0,07890988 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,0137092 0,07872155 ! positive regulation of binding GO:0051099 78 51 1,000 0,01423602 0,08155206 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,01423602 0,08135835 ! covalent chromatin modification GO:0016569 101 52 1,000 0,0147715 0,08421857 ! amino acid activation GO:0043038 92 52 1,000 0,0147715 0,08401947 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 1,000 0,0147715 0,08382131 ! synapse organization GO:0050808 85 52 1,000 0,0147715 0,08362408 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,01586818 0,08962169 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01642924 0,0925732 ! aging GO:0007568 103 55 1,000 0,01642924 0,0923569 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,01642924 0,09214162 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,0169987 0,09511364 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,0169987 0,09489296 ! muscle fiber development GO:0048747 112 57 1,000 0,01757648 0,09789124 ! lipid modification GO:0030258 97 57 1,000 0,01757648 0,09766516 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01763944 0,09778915 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01763944 0,09756435 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01763944 0,09734058 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01763944 0,09711783 ! neuron fate determination GO:0048664 7 5 0,000 0,01763944 0,0968961 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01763944 0,09667538 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01763944 0,09645566 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01763944 0,09623694 ! polyol transport GO:0015791 12 5 0,000 0,01763944 0,09601921 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01763944 0,09580246 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01763944 0,09558669 ! response to superoxide GO:0000303 10 5 0,000 0,01763944 0,09537189 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01763944 0,09515805 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01763944 0,09494517 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01763944 0,09473324 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01763944 0,09452225 ! female meiosis GO:0007143 7 5 0,000 0,01763944 0,0943122 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01763944 0,09410309 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01763944 0,09389489 ! cobalt ion transport GO:0006824 11 5 0,000 0,01763944 0,09368762 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01763944 0,09348126 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01763944 0,09327581 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01763944 0,09307125 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01763944 0,0928676 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01763944 0,09266483 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01763944 0,09246295 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01763944 0,09226194 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01763944 0,0920618 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01763944 0,09186254 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01763944 0,09166413 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01763944 0,09146658 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01763944 0,09126987 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01763944 0,09107402 ! negative chemotaxis GO:0050919 14 5 0,000 0,01763944 0,090879 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01763944 0,09068481 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01763944 0,09049145 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01763944 0,09029892 ! behavioral response to pain GO:0048266 9 5 0,000 0,01763944 0,0901072 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01763944 0,0899163 ! Notch receptor processing GO:0007220 8 5 0,000 0,01763944 0,0897262 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01763944 0,0895369 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01763944 0,0893484 ! micturition GO:0060073 9 5 0,000 0,01763944 0,0891607 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01763944 0,08897378 ! copulation GO:0007620 9 5 0,000 0,01763944 0,08878764 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01763944 0,08860228 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01763944 0,08841769 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01763944 0,08823387 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01763944 0,08805081 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01763944 0,08786851 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01763944 0,08768697 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01763944 0,08750617 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01763944 0,08732611 ! grooming behavior GO:0007625 6 5 0,000 0,01763944 0,0871468 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01763944 0,08696822 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01763944 0,08679037 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01763944 0,08661325 ! response to protozoan GO:0001562 10 5 0,000 0,01763944 0,08643685 ! lymph vessel development GO:0001945 10 5 0,000 0,01763944 0,08626116 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01763944 0,08608619 ! endochondral ossification GO:0001958 16 5 0,000 0,01763944 0,08591193 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01763944 0,08573837 ! parathyroid gland development GO:0060017 13 5 0,000 0,01763944 0,08556551 ! anagen GO:0042640 6 5 0,000 0,01763944 0,08539334 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01763944 0,08522187 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01763944 0,08505109 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01763944 0,08488098 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01763944 0,08471156 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01763944 0,08454281 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01763944 0,08437474 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01763944 0,08420733 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01763944 0,08404058 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01763944 0,08387449 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01763944 0,08370906 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01763944 0,08354428 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01763944 0,08338014 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01763944 0,08321665 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01763944 0,0830538 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01763944 0,08289159 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01763944 0,08273 ! histidine catabolic process GO:0006548 6 5 0,000 0,01763944 0,08256905 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01763944 0,08240872 ! microvillus organization GO:0032528 7 5 0,000 0,01763944 0,08224902 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01763944 0,08208993 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01763944 0,08193145 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01763944 0,08177359 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01763944 0,08161633 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01763944 0,08145968 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01763944 0,08130362 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01763944 0,08114817 ! polyol catabolic process GO:0046174 7 5 0,000 0,01763944 0,0809933 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01763944 0,08083903 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01763944 0,08068535 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01763944 0,08053224 ! muscle cell migration GO:0014812 8 5 0,000 0,01763944 0,08037972 ! mitochondrial fission GO:0000266 8 5 0,000 0,01763944 0,08022777 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01763944 0,0800764 ! mRNA transcription GO:0009299 9 5 0,000 0,01763944 0,0799256 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01763944 0,07977536 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01763944 0,07962569 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01763944 0,07947658 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01763944 0,07932802 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01763944 0,07918002 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01763944 0,07903257 ! response to food GO:0032094 6 5 0,000 0,01763944 0,07888567 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01763944 0,07873932 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01763944 0,0785935 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01763944 0,07844823 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01763944 0,07830349 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01763944 0,07815929 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01763944 0,07801561 ! forebrain neuron development GO:0021884 13 5 0,000 0,01763944 0,07787246 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01763944 0,07772984 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01763944 0,07758774 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01763944 0,07744615 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01763944 0,07730509 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01763944 0,07716453 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01763944 0,07702449 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01763944 0,07688495 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01763944 0,07674592 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01763944 0,07660739 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01763944 0,07646935 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01763944 0,07633182 ! basic amino acid transport GO:0015802 11 5 0,000 0,01763944 0,07619478 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01763944 0,07605823 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01763944 0,07592217 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01763944 0,07578659 ! depyrimidination GO:0045008 10 5 0,000 0,01763944 0,0756515 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01763944 0,07551689 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01763944 0,07538276 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01763944 0,0752491 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01763944 0,07511591 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01763944 0,0749832 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01763944 0,07485096 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01763944 0,07471918 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01763944 0,07458786 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01763944 0,074457 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01763944 0,07432661 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01763944 0,07419666 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01763944 0,07406718 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01763944 0,07393814 ! response to arsenic GO:0046685 10 5 0,000 0,01763944 0,07380955 ! mast cell degranulation GO:0043303 7 5 0,000 0,01763944 0,07368141 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01763944 0,07355371 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01763944 0,07342646 ! response to cadmium ion GO:0046686 7 5 0,000 0,01763944 0,07329964 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01763944 0,07317326 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01763944 0,07304732 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01763944 0,07292181 ! decidualization GO:0046697 11 5 0,000 0,01763944 0,07279673 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01763944 0,07267208 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01763944 0,07254785 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01763944 0,07242405 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01763944 0,07230067 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01763944 0,07217771 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01763944 0,07205516 ! neural tube patterning GO:0021532 7 5 0,000 0,01763944 0,07193304 ! embryonic cleavage GO:0040016 6 5 0,000 0,01763944 0,07181132 ! peroxisome fission GO:0016559 5 5 0,000 0,01763944 0,07169002 ! histone demethylation GO:0016577 10 5 0,000 0,01763944 0,07156913 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01763944 0,07144864 ! mitotic recombination GO:0006312 9 5 0,000 0,01763944 0,07132856 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01763944 0,07120888 ! metaphase plate congression GO:0051310 7 5 0,000 0,01763944 0,0710896 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01763944 0,07097072 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01763944 0,07085224 ! enteric nervous system development GO:0048484 8 5 0,000 0,01763944 0,07073415 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01763944 0,07061646 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01763944 0,07049916 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01763944 0,07038224 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01763944 0,07026571 ! plasminogen activation GO:0031639 5 5 0,000 0,01763944 0,07014957 ! B cell homeostasis GO:0001782 13 5 0,000 0,01763944 0,07003381 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01763944 0,06991844 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01763944 0,06980344 ! metaphase GO:0051323 8 5 0,000 0,01763944 0,06968882 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01763944 0,06957458 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01763944 0,06946071 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01763944 0,06934721 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01763944 0,06923408 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01763944 0,06912132 GO:0015991|ATP hydrolysis coupled proton transport, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01763944 0,06900893 ! response to redox state GO:0051775 5 5 0,000 0,01763944 0,0688969 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01763944 0,06878524 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01763944 0,06867393 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01763944 0,06856299 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01763944 0,06845241 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01763944 0,06834218 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01763944 0,0682323 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01763944 0,06812278 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01763944 0,06801361 ! striatum development GO:0021756 9 5 0,000 0,01763944 0,06790479 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01763944 0,06779631 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01763944 0,06768818 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01763944 0,0675804 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01763944 0,06747296 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01763944 0,06736586 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01763944 0,0672591 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01763944 0,06715268 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01763944 0,06704659 ! neuroprotection GO:0043526 6 5 0,000 0,01763944 0,06694084 ! neural plate development GO:0001840 8 5 0,000 0,01763944 0,06683542 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01763944 0,06673033 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01763944 0,06662558 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01763944 0,06652115 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01763944 0,06641705 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01763944 0,06631327 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01763944 0,06620982 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01763944 0,06610669 ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01763944 0,06600388 ! spindle assembly GO:0051225 6 5 0,000 0,01763944 0,06590138 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01763944 0,06579921 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01763944 0,06569736 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01763944 0,06559581 ! drug metabolic process GO:0017144 6 5 0,000 0,01763944 0,06549459 ! phospholipid scrambling GO:0017121 8 5 0,000 0,01763944 0,06539367 ! organ regeneration GO:0031100 7 5 0,000 0,01763944 0,06529306 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01763944 0,06519277 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01763944 0,06509278 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01763944 0,0649931 ! adult behavior GO:0030534 99 58 1,000 0,01816253 0,06681811 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,01875677 0,06889893 ! DNA catabolic process GO:0006308 86 59 1,000 0,01875677 0,0687939 ! regulation of heart contraction GO:0008016 110 60 1,000 0,01935916 0,07089517 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,01935916 0,07078743 ! ear development GO:0043583 103 62 1,000 0,02058806 0,07516673 ! viral reproductive process GO:0022415 126 62 1,000 0,02058806 0,07505284 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02113016 0,0769125 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02113016 0,07679632 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02113016 0,07668049 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02113016 0,07656501 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02113016 0,07644987 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02113016 0,07633508 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02113016 0,07622064 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02113016 0,07610654 ! sleep GO:0030431 13 6 0,000 0,02113016 0,07599277 ! response to oxygen radical GO:0000305 11 6 0,000 0,02113016 0,07587935 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02113016 0,07576627 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02113016 0,07565352 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02113016 0,07554111 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02113016 0,07542903 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02113016 0,07531728 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02113016 0,07520587 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02113016 0,07509478 ! forebrain regionalization GO:0021871 8 6 0,000 0,02113016 0,07498402 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02113016 0,07487359 ! male meiosis GO:0007140 7 6 0,000 0,02113016 0,07476348 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02113016 0,07465369 ! response to zinc ion GO:0010043 9 6 0,000 0,02113016 0,07454423 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02113016 0,07443509 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02113016 0,07432627 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02113016 0,07421776 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02113016 0,07410957 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02113016 0,0740017 ! malate metabolic process GO:0006108 11 6 0,000 0,02113016 0,07389414 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02113016 0,07378689 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02113016 0,07367995 ! protein refolding GO:0042026 15 6 0,000 0,02113016 0,07357332 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02113016 0,073467 ! opsonization GO:0008228 8 6 0,000 0,02113016 0,07336099 ! mating behavior GO:0007617 7 6 0,000 0,02113016 0,07325528 ! neuron remodeling GO:0016322 15 6 0,000 0,02113016 0,07314988 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02113016 0,07304478 ! equilibrioception GO:0050957 14 6 0,000 0,02113016 0,07293998 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02113016 0,07283548 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02113016 0,07273128 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02113016 0,07262738 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02113016 0,07252377 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02113016 0,07242046 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02113016 0,07231745 ! toxin metabolic process GO:0009404 11 6 0,000 0,02113016 0,07221472 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02113016 0,07211229 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02113016 0,07201015 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02113016 0,0719083 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02113016 0,07180673 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02113016 0,07170545 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02113016 0,07160446 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02113016 0,07150375 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02113016 0,07140332 ! protein lipoylation GO:0009249 10 6 0,000 0,02113016 0,07130318 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02113016 0,07120331 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02113016 0,07110373 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02113016 0,07100442 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02113016 0,07090539 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02113016 0,07080664 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02113016 0,07070816 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02113016 0,07060995 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02113016 0,07051202 ! hyperosmotic response GO:0006972 9 6 0,000 0,02113016 0,07041436 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02113016 0,07031696 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02113016 0,07021984 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02113016 0,07012299 ! urea metabolic process GO:0019627 7 6 0,000 0,02113016 0,0700264 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02113016 0,06993008 ! neutrophil activation GO:0042119 8 6 0,000 0,02113016 0,06983402 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02113016 0,06973822 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02113016 0,06964269 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02113016 0,06954742 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02113016 0,06945241 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02113016 0,06935766 ! neuron apoptosis GO:0051402 9 6 0,000 0,02113016 0,06926317 ! nucleoside salvage GO:0043174 9 6 0,000 0,02113016 0,06916893 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02113016 0,06907495 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02113016 0,06898123 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02113016 0,06888776 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02113016 0,06879454 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02113016 0,06870158 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02113016 0,06860886 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02113016 0,0685164 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02113016 0,06842418 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02113016 0,06833221 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02113016 0,06824049 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02113016 0,06814902 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02113016 0,06805779 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02113016 0,0679668 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02113016 0,06787606 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02113016 0,06778555 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02113016 0,06769529 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02113016 0,06760527 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02113016 0,06751549 ! neural nucleus development GO:0048857 14 6 0,000 0,02113016 0,06742595 ! response to UV-C GO:0010225 11 6 0,000 0,02113016 0,06733664 ! astrocyte development GO:0014002 15 6 0,000 0,02113016 0,06724757 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02113016 0,06715874 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02113016 0,06707014 ! interaction with symbiont GO:0051702 13 6 0,000 0,02113016 0,06698177 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02113016 0,06689364 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02113016 0,06680574 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02113016 0,06671807 ! response to copper ion GO:0046688 10 6 0,000 0,02113016 0,06663062 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02113016 0,06654341 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02113016 0,06645643 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02113016 0,06636967 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02113016 0,06628314 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02113016 0,06619683 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02113016 0,06611075 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02113016 0,06602489 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02113016 0,06593926 ! hair follicle maturation GO:0048820 7 6 0,000 0,02113016 0,06585384 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02113016 0,06576865 ! Schwann cell development GO:0014044 15 6 0,000 0,02113016 0,06568368 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02113016 0,06559892 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02113016 0,06551439 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02113016 0,06543007 ! subpallium development GO:0021544 10 6 0,000 0,02113016 0,06534597 ! histone ubiquitination GO:0016574 8 6 0,000 0,02113016 0,06526209 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02113016 0,06517842 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02113016 0,06509496 ! G2 phase GO:0051319 16 6 0,000 0,02113016 0,06501172 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02113016 0,06492869 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02113016 0,06484587 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02113016 0,06476327 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02113016 0,06468087 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02113016 0,06459869 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02113016 0,06451671 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02113016 0,06443494 ! receptor internalization GO:0031623 10 6 0,000 0,02113016 0,06435337 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02113016 0,06427202 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02113016 0,06419087 ! protein deubiquitination GO:0016579 14 6 0,000 0,02113016 0,06410992 ! protein destabilization GO:0031648 9 6 0,000 0,02113016 0,06402918 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02113016 0,06394864 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02113016 0,0638683 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02113016 0,06378816 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02113016 0,06370823 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02113016 0,06362849 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02113016 0,06354896 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02113016 0,06346962 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02113016 0,06339048 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02113016 0,06331154 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02113016 0,06323279 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02113016 0,06315424 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02113016 0,06307589 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02113016 0,06299773 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02113016 0,06291976 ! catecholamine transport GO:0051937 9 6 0,000 0,02113016 0,06284198 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02113016 0,0627644 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02113016 0,06268701 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02113016 0,06260981 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02113016 0,0625328 ! maternal placenta development GO:0001893 12 6 0,000 0,02113016 0,06245598 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02113016 0,06237934 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02113016 0,0623029 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02113016 0,06222664 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02113016 0,06215057 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02113016 0,06207468 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02113016 0,06199898 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02113016 0,06192347 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,02121446 0,06209488 ! detection of external stimulus GO:0009581 91 63 1,000 0,02121446 0,06201943 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,02121446 0,06194416 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,02249083 0,06559144 ! actin filament organization GO:0007015 148 66 1,000 0,02314068 0,06740494 ! extracellular matrix organization GO:0030198 133 66 1,000 0,02314068 0,06732343 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,02379822 0,0691528 ! lung development GO:0030324 144 67 1,000 0,02379822 0,06906939 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,02379822 0,06898617 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,02379822 0,06890315 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,02379822 0,06882034 ! activation of immune response GO:0002253 105 67 1,000 0,02379822 0,06873772 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,02446339 0,07057425 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,02446339 0,07048973 ! viral reproduction GO:0016032 134 68 1,000 0,02446339 0,07040541 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,02446339 0,07032129 ! tRNA transcription GO:0009304 14 7 0,000 0,02460859 0,07065426 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02460859 0,07057005 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02460859 0,07048604 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02460859 0,07040223 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02460859 0,07031861 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02460859 0,0702352 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02460859 0,07015198 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02460859 0,07006896 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02460859 0,06998614 ! prostate gland development GO:0030850 13 7 0,000 0,02460859 0,06990351 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02460859 0,06982108 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02460859 0,06973884 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02460859 0,06965679 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02460859 0,06957494 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02460859 0,06949328 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02460859 0,06941181 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02460859 0,06933053 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02460859 0,06924944 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02460859 0,06916854 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02460859 0,06908783 ! glycolipid transport GO:0046836 10 7 0,000 0,02460859 0,06900731 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02460859 0,06892698 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02460859 0,06884683 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02460859 0,06876687 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02460859 0,06868709 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02460859 0,0686075 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02460859 0,06852809 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02460859 0,06844887 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02460859 0,06836983 ! mRNA stabilization GO:0048255 18 7 0,000 0,02460859 0,06829097 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02460859 0,0682123 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02460859 0,0681338 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02460859 0,06805549 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02460859 0,06797735 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02460859 0,0678994 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02460859 0,06782162 ! lipoprotein transport GO:0042953 14 7 0,000 0,02460859 0,06774402 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02460859 0,0676666 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02460859 0,06758935 ! rhythmic behavior GO:0007622 15 7 0,000 0,02460859 0,06751228 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02460859 0,06743539 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02460859 0,06735867 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02460859 0,06728213 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02460859 0,06720576 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02460859 0,06712956 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02460859 0,06705354 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02460859 0,06697769 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02460859 0,066902 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02460859 0,06682649 ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02460859 0,06675115 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02460859 0,06667598 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02460859 0,06660098 ! spinal cord patterning GO:0021511 13 7 0,000 0,02460859 0,06652615 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02460859 0,06645149 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02460859 0,06637699 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02460859 0,06630266 ! adrenal gland development GO:0030325 17 7 0,000 0,02460859 0,06622849 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02460859 0,0661545 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02460859 0,06608066 ! ovulation GO:0030728 9 7 0,000 0,02460859 0,06600699 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02460859 0,06593349 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02460859 0,06586015 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02460859 0,06578697 ! microtubule nucleation GO:0007020 20 7 0,000 0,02460859 0,06571396 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02460859 0,0656411 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02460859 0,06556841 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02460859 0,06549588 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02460859 0,06542351 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02460859 0,0653513 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02460859 0,06527924 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02460859 0,06520735 ! galactose metabolic process GO:0006012 13 7 0,000 0,02460859 0,06513561 ! vesicle fusion GO:0006906 17 7 0,000 0,02460859 0,06506404 ! response to dietary excess GO:0002021 8 7 0,000 0,02460859 0,06499262 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02460859 0,06492135 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02460859 0,06485024 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02460859 0,06477929 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02460859 0,0647085 ! organ growth GO:0035265 15 7 0,000 0,02460859 0,06463785 ! purine salvage GO:0043101 10 7 0,000 0,02460859 0,06456736 ! nucleoside transport GO:0015858 8 7 0,000 0,02460859 0,06449703 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02460859 0,06442685 ! parturition GO:0007567 14 7 0,000 0,02460859 0,06435682 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02460859 0,06428694 ! rRNA modification GO:0000154 14 7 0,000 0,02460859 0,06421722 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02460859 0,06414764 ! spindle checkpoint GO:0031577 15 7 0,000 0,02460859 0,06407822 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02460859 0,06400894 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02460859 0,06393982 ! macrophage differentiation GO:0030225 11 7 0,000 0,02460859 0,06387085 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02460859 0,06380202 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02460859 0,06373334 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02460859 0,06366481 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02460859 0,06359643 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02460859 0,06352819 ! fibrinolysis GO:0042730 10 7 0,000 0,02460859 0,0634601 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02460859 0,06339216 ! eating behavior GO:0042755 7 7 0,000 0,02460859 0,06332436 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02460859 0,0632567 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02460859 0,06318919 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02460859 0,06312183 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02460859 0,0630546 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02460859 0,06298753 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02460859 0,06292059 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02460859 0,06285379 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02460859 0,06278714 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02460859 0,06272063 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02460859 0,06265426 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02460859 0,06258803 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02460859 0,06252194 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02460859 0,06245598 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02460859 0,06239017 ! regulation of meiosis GO:0040020 12 7 0,000 0,02460859 0,0623245 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02460859 0,06225896 ! regulation of lipid transport GO:0032368 14 7 0,000 0,02460859 0,06219356 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02460859 0,0621283 ! transcription termination GO:0006353 13 7 0,000 0,02460859 0,06206318 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02460859 0,06199819 ! anaphase GO:0051322 17 7 0,000 0,02460859 0,06193334 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02460859 0,06186862 ! axonal fasciculation GO:0007413 18 7 0,000 0,02460859 0,06180404 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02460859 0,0617396 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02460859 0,06167529 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02460859 0,06161111 ! diuresis GO:0030146 12 7 0,000 0,02460859 0,06154706 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02460859 0,06148315 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02460859 0,06141937 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02460859 0,06135572 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02460859 0,06129221 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02460859 0,06122882 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02460859 0,06116557 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02460859 0,06110245 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02460859 0,06103946 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02460859 0,06097659 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02460859 0,06091386 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02460859 0,06085126 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02460859 0,06078878 ! lymph node development GO:0048535 10 7 0,000 0,02460859 0,06072643 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02460859 0,06066421 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02460859 0,06060212 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02460859 0,06054016 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02460859 0,06047832 ! adult feeding behavior GO:0008343 9 7 0,000 0,02460859 0,06041661 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02460859 0,06035502 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02460859 0,06029356 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02460859 0,06023222 ! muscle adaptation GO:0043500 14 7 0,000 0,02460859 0,06017101 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02460859 0,06010992 ! retina homeostasis GO:0001895 12 7 0,000 0,02460859 0,06004896 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02460859 0,05998812 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02460859 0,0599274 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02460859 0,05986681 ! protein prenylation GO:0018342 18 7 0,000 0,02460859 0,05980634 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02460859 0,05974599 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02460859 0,05968576 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02460859 0,05962565 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,02513613 0,06084259 ! respiratory tube development GO:0030323 150 70 1,000 0,02581638 0,06242634 ! B cell activation GO:0042113 160 71 1,000 0,02650408 0,06402491 ! regulation of immune effector process GO:0002697 137 71 1,000 0,02650408 0,06396069 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02719916 0,06557232 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,02719916 0,06550668 ! carbohydrate transport GO:0008643 110 72 1,000 0,02719916 0,06544117 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,02719916 0,0653758 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,02719916 0,06531055 ! respiratory system development GO:0060541 153 72 1,000 0,02719916 0,06524544 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02807478 0,0672788 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02807478 0,06721186 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02807478 0,06714505 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02807478 0,06707837 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02807478 0,06701182 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02807478 0,06694541 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02807478 0,06687913 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02807478 0,06681298 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02807478 0,06674696 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02807478 0,06668106 ! meiotic prophase I GO:0007128 13 8 0,000 0,02807478 0,0666153 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02807478 0,06654967 ! oligopeptide transport GO:0006857 15 8 0,000 0,02807478 0,06648417 ! UTP metabolic process GO:0046051 8 8 0,000 0,02807478 0,0664188 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02807478 0,06635355 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02807478 0,06628844 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02807478 0,06622345 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02807478 0,06615859 ! succinate metabolic process GO:0006105 14 8 0,000 0,02807478 0,06609385 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02807478 0,06602925 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02807478 0,06596476 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02807478 0,06590041 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02807478 0,06583618 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02807478 0,06577207 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02807478 0,06570809 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02807478 0,06564424 ! reflex GO:0060004 16 8 0,000 0,02807478 0,0655805 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02807478 0,06551689 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02807478 0,06545341 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02807478 0,06539005 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02807478 0,06532681 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02807478 0,06526369 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02807478 0,06520069 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02807478 0,06513782 ! pigment granule organization GO:0048753 16 8 0,000 0,02807478 0,06507507 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02807478 0,06501243 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02807478 0,06494992 ! histidine metabolic process GO:0006547 16 8 0,000 0,02807478 0,06488753 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02807478 0,06482526 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02807478 0,06476311 ! glycine catabolic process GO:0006546 13 8 0,000 0,02807478 0,06470107 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02807478 0,06463916 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02807478 0,06457736 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02807478 0,06451568 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02807478 0,06445412 ! melanin metabolic process GO:0006582 15 8 0,000 0,02807478 0,06439268 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02807478 0,06433135 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02807478 0,06427014 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02807478 0,06420905 ! macrophage activation GO:0042116 12 8 0,000 0,02807478 0,06414807 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02807478 0,06408721 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02807478 0,06402646 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02807478 0,06396583 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02807478 0,06390532 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02807478 0,06384491 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02807478 0,06378463 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02807478 0,06372445 ! osteoblast development GO:0002076 16 8 0,000 0,02807478 0,06366439 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02807478 0,06360444 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02807478 0,06354461 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02807478 0,06348489 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02807478 0,06342528 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02807478 0,06336578 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02807478 0,06330639 ! response to UV-B GO:0010224 16 8 0,000 0,02807478 0,06324711 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02807478 0,06318795 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02807478 0,0631289 ! intermediate filament organization GO:0045109 12 8 0,000 0,02807478 0,06306995 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02807478 0,06301112 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02807478 0,06295239 ! cellular extravasation GO:0045123 12 8 0,000 0,02807478 0,06289378 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02807478 0,06283527 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02807478 0,06277688 ! response to antibiotic GO:0046677 11 8 0,000 0,02807478 0,06271859 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02807478 0,06266041 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02807478 0,06260233 ! DNA topological change GO:0006265 12 8 0,000 0,02807478 0,06254437 ! response to tropane GO:0014073 15 8 0,000 0,02807478 0,06248651 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02807478 0,06242876 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02807478 0,06237112 ! melanosome transport GO:0032402 13 8 0,000 0,02807478 0,06231358 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02807478 0,06225615 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02807478 0,06219882 ! mast cell activation GO:0045576 14 8 0,000 0,02807478 0,0621416 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02807478 0,06208448 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02807478 0,06202747 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02807478 0,06197057 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02807478 0,06191377 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02807478 0,06185707 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02807478 0,06180047 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02807478 0,06174398 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02807478 0,0616876 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02807478 0,06163131 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02807478 0,06157513 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02807478 0,06151905 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02807478 0,06146307 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02807478 0,0614072 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02807478 0,06135142 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02807478 0,06129575 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02807478 0,06124018 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02807478 0,06118471 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02807478 0,06112934 ! hormone catabolic process GO:0042447 17 8 0,000 0,02807478 0,06107407 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02807478 0,0610189 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02807478 0,06096383 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02807478 0,06090885 ! ATP catabolic process GO:0006200 11 8 0,000 0,02807478 0,06085398 ! blastocyst growth GO:0001832 19 8 0,000 0,02807478 0,06079921 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02807478 0,06074453 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02807478 0,06068995 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02807478 0,06063547 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02807478 0,06058109 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02807478 0,06052681 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02807478 0,06047262 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02807478 0,06041853 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02807478 0,06036454 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02807478 0,06031064 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02807478 0,06025684 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02807478 0,06020314 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02807478 0,06014953 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02807478 0,06009601 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02807478 0,06004259 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02807478 0,05998927 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,02861124 0,06108132 GO:0090046|regulation of transcription regulator activity, ! eye development GO:0001654 143 74 1,000 0,02861124 0,06102717 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,02932812 0,06250086 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,02932812 0,06244554 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,03005215 0,06393058 ! regulation of catabolic process GO:0009894 161 76 1,000 0,03005215 0,0638741 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,03078327 0,06537031 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,03152142 0,06687879 ! axon extension GO:0048675 15 9 0,000 0,03152876 0,06683542 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03152876 0,06677659 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03152876 0,06671786 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03152876 0,06665923 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03152876 0,06660071 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03152876 0,06654228 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03152876 0,06648396 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03152876 0,06642575 ! phosphate transport GO:0006817 19 9 0,000 0,03152876 0,06636763 ! reproductive behavior GO:0019098 19 9 0,000 0,03152876 0,06630962 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03152876 0,06625171 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03152876 0,0661939 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03152876 0,06613618 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03152876 0,06607857 ! GTP metabolic process GO:0046039 9 9 0,000 0,03152876 0,06602107 ! RNA methylation GO:0001510 15 9 0,000 0,03152876 0,06596366 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03152876 0,06590635 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03152876 0,06584914 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03152876 0,06579202 ! artery development GO:0060840 24 9 0,000 0,03152876 0,06573501 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03152876 0,0656781 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03152876 0,06562128 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03152876 0,06556457 ! chemosensory behavior GO:0007635 20 9 0,000 0,03152876 0,06550795 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03152876 0,06545143 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03152876 0,065395 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03152876 0,06533868 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03152876 0,06528245 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03152876 0,06522631 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03152876 0,06517028 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03152876 0,06511434 ! protein targeting to ER GO:0045047 22 9 0,000 0,03152876 0,06505849 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03152876 0,06500275 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03152876 0,06494709 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03152876 0,06489153 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03152876 0,06483607 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03152876 0,0647807 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03152876 0,06472543 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03152876 0,06467025 ! mannose metabolic process GO:0006013 13 9 0,000 0,03152876 0,06461517 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03152876 0,06456017 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03152876 0,06450528 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03152876 0,06445047 ! receptor clustering GO:0043113 18 9 0,000 0,03152876 0,06439576 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03152876 0,06434114 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03152876 0,06428661 ! ruffle organization GO:0031529 15 9 0,000 0,03152876 0,06423218 ! retinol metabolic process GO:0042572 18 9 0,000 0,03152876 0,06417784 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03152876 0,06412359 ! behavioral fear response GO:0001662 22 9 0,000 0,03152876 0,06406943 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03152876 0,06401536 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03152876 0,06396139 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03152876 0,0639075 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03152876 0,06385371 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03152876 0,0638 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03152876 0,06374639 ! segment specification GO:0007379 13 9 0,000 0,03152876 0,06369287 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03152876 0,06363943 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03152876 0,06358609 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03152876 0,06353283 ! response to amine stimulus GO:0014075 13 9 0,000 0,03152876 0,06347967 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03152876 0,06342659 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03152876 0,0633736 ! erythrocyte development GO:0048821 15 9 0,000 0,03152876 0,0633207 ! gas homeostasis GO:0033483 16 9 0,000 0,03152876 0,06326789 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03152876 0,06321517 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03152876 0,06316253 ! renal water homeostasis GO:0003091 14 9 0,000 0,03152876 0,06310999 ! postreplication repair GO:0006301 22 9 0,000 0,03152876 0,06305753 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03152876 0,06300515 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03152876 0,06295287 ! icosanoid secretion GO:0032309 15 9 0,000 0,03152876 0,06290067 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03152876 0,06284855 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03152876 0,06279653 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03152876 0,06274459 ! regulation of cell division GO:0051302 15 9 0,000 0,03152876 0,06269273 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03152876 0,06264096 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03152876 0,06258928 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03152876 0,06253768 ! sterol catabolic process GO:0016127 11 9 0,000 0,03152876 0,06248616 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03152876 0,06243474 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03152876 0,06238339 ! S phase GO:0051320 9 9 0,000 0,03152876 0,06233213 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03152876 0,06228096 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03152876 0,06222986 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03152876 0,06217886 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03152876 0,06212793 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03152876 0,06207709 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03152876 0,06202633 ! purine base metabolic process GO:0006144 21 9 0,000 0,03152876 0,06197566 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03152876 0,06192506 ! pigment granule transport GO:0051904 17 9 0,000 0,03152876 0,06187455 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03152876 0,06182413 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03152876 0,06177378 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03152876 0,06172352 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03152876 0,06167334 ! mitochondrion localization GO:0051646 15 9 0,000 0,03152876 0,06162324 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,03226655 0,06301405 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,03226655 0,06296295 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,03226655 0,06291192 ! response to metal ion GO:0010038 140 80 1,000 0,03301859 0,06432609 ! muscle cell differentiation GO:0042692 159 80 1,000 0,03301859 0,06427404 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,03377748 0,06569816 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,03377748 0,06564509 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,03377748 0,06559211 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03497059 0,06785422 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03497059 0,06779954 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03497059 0,06774495 ! synapsis GO:0007129 13 10 0,000 0,03497059 0,06769045 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03497059 0,06763604 ! N-glycan processing GO:0006491 20 10 0,000 0,03497059 0,06758171 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03497059 0,06752747 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03497059 0,06747332 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03497059 0,06741926 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03497059 0,06736528 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03497059 0,06731138 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03497059 0,06725758 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03497059 0,06720386 ! androgen metabolic process GO:0008209 17 10 0,000 0,03497059 0,06715022 ! phospholipid efflux GO:0033700 16 10 0,000 0,03497059 0,06709668 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03497059 0,06704321 ! lung alveolus development GO:0048286 26 10 0,000 0,03497059 0,06698983 ! pathogenesis GO:0009405 13 10 0,000 0,03497059 0,06693654 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03497059 0,06688333 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03497059 0,06683021 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03497059 0,06677717 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03497059 0,06672421 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03497059 0,06667134 ! endoderm development GO:0007492 16 10 0,000 0,03497059 0,06661855 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03497059 0,06656585 ! arginine catabolic process GO:0006527 13 10 0,000 0,03497059 0,06651323 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03497059 0,06646069 ! proline metabolic process GO:0006560 13 10 0,000 0,03497059 0,06640823 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03497059 0,06635586 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03497059 0,06630357 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03497059 0,06625136 ! V(D)J recombination GO:0033151 28 10 0,000 0,03497059 0,06619924 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03497059 0,06614719 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03497059 0,06609523 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03497059 0,06604335 ! B cell proliferation GO:0042100 18 10 0,000 0,03497059 0,06599155 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03497059 0,06593984 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03497059 0,0658882 ! multicellular organism growth GO:0035264 18 10 0,000 0,03497059 0,06583664 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03497059 0,06578517 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03497059 0,06573377 ! epithelial cell development GO:0002064 20 10 0,000 0,03497059 0,06568246 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03497059 0,06563123 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03497059 0,06558007 ! macroautophagy GO:0016236 17 10 0,000 0,03497059 0,065529 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03497059 0,065478 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03497059 0,06542708 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03497059 0,06537625 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03497059 0,06532549 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03497059 0,06527481 ! brain morphogenesis GO:0048854 23 10 0,000 0,03497059 0,06522421 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03497059 0,06517369 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03497059 0,06512324 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03497059 0,06507288 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03497059 0,06502259 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03497059 0,06497238 ! response to dsRNA GO:0043331 20 10 0,000 0,03497059 0,06492225 ! DNA ligation GO:0006266 19 10 0,000 0,03497059 0,06487219 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03497059 0,06482221 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03497059 0,06477231 ! melanosome localization GO:0032400 16 10 0,000 0,03497059 0,06472249 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03497059 0,06467274 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03497059 0,06462307 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03497059 0,06457347 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03497059 0,06452395 ! mRNA cleavage GO:0006379 17 10 0,000 0,03497059 0,06447451 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03497059 0,06442514 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03497059 0,06437585 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03497059 0,06432663 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03497059 0,06427749 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03497059 0,06422842 ! prophase GO:0051324 15 10 0,000 0,03497059 0,06417943 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03497059 0,06413051 ! apical protein localization GO:0045176 15 10 0,000 0,03497059 0,06408167 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03497059 0,0640329 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03497059 0,06398421 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03497059 0,06393559 ! midbrain development GO:0030901 13 10 0,000 0,03497059 0,06388704 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03497059 0,06383857 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03497059 0,06379017 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03497059 0,06374184 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03497059 0,06369359 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03497059 0,06364541 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03497059 0,0635973 ! detection of calcium ion GO:0005513 23 10 0,000 0,03497059 0,06354927 ! oocyte development GO:0048599 17 10 0,000 0,03497059 0,06350131 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03497059 0,06345342 ! blastocyst formation GO:0001825 17 10 0,000 0,03497059 0,0634056 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03497059 0,06335785 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03497059 0,06331018 ! activation of innate immune response GO:0002218 12 10 0,000 0,03497059 0,06326258 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03497059 0,06321505 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03497059 0,06316759 ! response to nicotine GO:0035094 20 10 0,000 0,03497059 0,0631202 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03497059 0,06307289 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03497059 0,06302564 ! localization within membrane GO:0051668 20 10 0,000 0,03497059 0,06297847 ! regulation of ligase activity GO:0051340 142 84 1,000 0,03609474 0,06495434 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,03609474 0,06490579 ! response to unfolded protein GO:0006986 131 85 1,000 0,0368805 0,06626921 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,0368805 0,06621976 ! amine biosynthetic process GO:0009309 138 86 1,000 0,03767283 0,06759196 ! response to inorganic substance GO:0010035 153 86 1,000 0,03767283 0,0675416 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03840029 0,06879457 ! respiratory burst GO:0045730 17 11 0,000 0,03840029 0,06874338 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03840029 0,06869227 ! neuron fate specification GO:0048665 17 11 0,000 0,03840029 0,06864124 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03840029 0,06859028 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03840029 0,06853939 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03840029 0,06848859 ! thyroid gland development GO:0030878 26 11 0,000 0,03840029 0,06843785 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,03840029 0,0683872 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03840029 0,06833661 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03840029 0,06828611 ! response to pain GO:0048265 24 11 0,000 0,03840029 0,06823567 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03840029 0,06818532 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03840029 0,06813503 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03840029 0,06808482 ! bone resorption GO:0045453 16 11 0,000 0,03840029 0,06803469 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03840029 0,06798462 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03840029 0,06793463 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03840029 0,06788472 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03840029 0,06783488 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03840029 0,06778511 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03840029 0,06773541 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03840029 0,06768579 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03840029 0,06763624 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03840029 0,06758676 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03840029 0,06753736 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03840029 0,06748802 ! UV protection GO:0009650 19 11 0,000 0,03840029 0,06743876 ! adult heart development GO:0007512 14 11 0,000 0,03840029 0,06738957 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03840029 0,06734045 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03840029 0,06729141 ! temperature homeostasis GO:0001659 17 11 0,000 0,03840029 0,06724243 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03840029 0,06719353 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03840029 0,0671447 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03840029 0,06709594 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03840029 0,06704724 ! regulation of organ growth GO:0046620 13 11 0,000 0,03840029 0,06699862 ! pigment granule localization GO:0051875 20 11 0,000 0,03840029 0,06695007 ! vasoconstriction GO:0042310 18 11 0,000 0,03840029 0,0669016 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03840029 0,06685319 ! embryonic axis specification GO:0000578 18 11 0,000 0,03840029 0,06680485 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03840029 0,06675658 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03840029 0,06670838 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03840029 0,06666025 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03840029 0,06661219 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03840029 0,0665642 ! zymogen activation GO:0031638 15 11 0,000 0,03840029 0,06651627 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03840029 0,06646842 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03840029 0,06642063 ! nucleosome positioning GO:0016584 15 11 0,000 0,03840029 0,06637292 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03840029 0,06632527 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03840029 0,06627769 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03840029 0,06623018 ! acid secretion GO:0046717 18 11 0,000 0,03840029 0,06618274 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03840029 0,06613536 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03840029 0,06608806 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03840029 0,06604082 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03840029 0,06599364 ! oocyte differentiation GO:0009994 18 11 0,000 0,03840029 0,06594654 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03840029 0,0658995 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,03840029 0,06585253 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03840029 0,06580563 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03840029 0,06575879 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03840029 0,06571202 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03840029 0,06566532 ! embryonic gut development GO:0048566 15 11 0,000 0,03840029 0,06561868 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03840029 0,06557211 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03840029 0,0655256 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03840029 0,06547917 ! defense response to fungus GO:0050832 13 11 0,000 0,03840029 0,06543279 ! developmental induction GO:0031128 19 11 0,000 0,03840029 0,06538648 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03840029 0,06534024 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03840029 0,06529407 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03840029 0,06524795 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03840029 0,06520191 ! nucleus localization GO:0051647 19 11 0,000 0,03840029 0,06515593 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03840029 0,06511001 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,03927699 0,0665496 ! regulation of DNA binding GO:0051101 155 88 1,000 0,03927699 0,06650277 ! ATP biosynthetic process GO:0006754 159 88 1,000 0,03927699 0,066456 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,04008871 0,06778175 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,04008871 0,06773415 ! ossification GO:0001503 188 90 1,000 0,04090678 0,06906787 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,04090678 0,06901944 ! bone development GO:0060348 189 91 1,000 0,04173115 0,07036101 ! response to protein stimulus GO:0051789 149 91 1,000 0,04173115 0,07031173 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04181792 0,07040862 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04181792 0,07035939 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04181792 0,07031022 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04181792 0,07026112 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04181792 0,07021209 ! cartilage condensation GO:0001502 20 12 0,000 0,04181792 0,07016312 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,04181792 0,07011423 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04181792 0,0700654 ! protein complex disassembly GO:0043241 27 12 0,000 0,04181792 0,07001665 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04181792 0,06996796 ! hippocampus development GO:0021766 26 12 0,000 0,04181792 0,06991933 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04181792 0,06987078 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04181792 0,06982229 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04181792 0,06977387 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04181792 0,06972552 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04181792 0,06967723 ! drug transport GO:0015893 16 12 0,000 0,04181792 0,06962901 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04181792 0,06958086 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04181792 0,06953277 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04181792 0,06948475 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04181792 0,0694368 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04181792 0,06938891 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04181792 0,06934109 ! forebrain cell migration GO:0021885 21 12 0,000 0,04181792 0,06929333 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04181792 0,06924564 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04181792 0,06919802 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04181792 0,06915046 ! entry into host cell GO:0030260 32 12 0,000 0,04181792 0,06910297 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,04181792 0,06905554 ! monoamine transport GO:0015844 18 12 0,000 0,04181792 0,06900818 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04181792 0,06896088 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04181792 0,06891364 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04181792 0,06886648 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04181792 0,06881937 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04181792 0,06877233 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04181792 0,06872536 ! protein homotetramerization GO:0051289 21 12 0,000 0,04181792 0,06867844 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04181792 0,0686316 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04181792 0,06858481 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04181792 0,06853809 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04181792 0,06849144 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04181792 0,06844484 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04181792 0,06839831 ! cranial nerve development GO:0021545 20 12 0,000 0,04181792 0,06835185 ! fucose catabolic process GO:0019317 22 12 0,000 0,04181792 0,06830545 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04181792 0,0682591 ! histone methylation GO:0016571 26 12 0,000 0,04181792 0,06821283 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04181792 0,06816661 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04181792 0,06812046 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04181792 0,06807437 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04181792 0,06802834 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04181792 0,06798238 ! spleen development GO:0048536 22 12 0,000 0,04181792 0,06793648 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04181792 0,06789063 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04181792 0,06784486 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04181792 0,06779914 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04181792 0,06775348 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04181792 0,06770789 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04181792 0,06766235 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04181792 0,06761688 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04181792 0,06757147 ! response to cold GO:0009409 17 12 0,000 0,04181792 0,06752612 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04181792 0,06748083 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04181792 0,0674356 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,04339858 0,0699377 GO:0010498|proteasomal protein catabolic process, ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,04339858 0,06989089 ! transcription initiation GO:0006352 153 94 1,000 0,04424153 0,07120074 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04522352 0,07273248 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04522352 0,07268389 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04522352 0,07263537 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04522352 0,07258692 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04522352 0,07253852 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04522352 0,0724902 ! lipid localization GO:0010876 28 13 0,000 0,04522352 0,07244193 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04522352 0,07239374 ! organelle fusion GO:0048284 32 13 0,000 0,04522352 0,0723456 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04522352 0,07229753 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04522352 0,07224953 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04522352 0,07220158 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04522352 0,0721537 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04522352 0,07210589 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04522352 0,07205814 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04522352 0,07201045 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04522352 0,07196282 ! methionine metabolic process GO:0006555 27 13 0,000 0,04522352 0,07191526 ! plasma membrane organization GO:0007009 24 13 0,000 0,04522352 0,07186776 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04522352 0,07182032 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04522352 0,07177295 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04522352 0,07172563 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04522352 0,07167838 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04522352 0,0716312 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04522352 0,07158407 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,04522352 0,07153701 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04522352 0,07149 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04522352 0,07144306 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04522352 0,07139618 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04522352 0,07134937 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04522352 0,07130261 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04522352 0,07125592 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04522352 0,07120928 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04522352 0,07116271 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04522352 0,0711162 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04522352 0,07106975 ! ribosome assembly GO:0042255 17 13 0,000 0,04522352 0,07102336 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,04522352 0,07097703 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04522352 0,07093076 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04522352 0,07088455 ! chromatin silencing GO:0006342 26 13 0,000 0,04522352 0,0708384 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04522352 0,07079231 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04522352 0,07074628 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04522352 0,07070032 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04522352 0,07065441 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,04522352 0,07060856 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04522352 0,07056277 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04522352 0,07051704 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04522352 0,07047136 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04522352 0,07042575 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04522352 0,0703802 ! embryonic placenta development GO:0001892 23 13 0,000 0,04522352 0,0703347 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04522352 0,07028927 ! insulin secretion GO:0030073 23 13 0,000 0,04522352 0,07024389 ! actin filament polymerization GO:0030041 24 13 0,000 0,04522352 0,07019857 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04522352 0,07015331 ! acrosome reaction GO:0007340 18 13 0,000 0,04522352 0,07010811 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 1,000 0,04594562 0,07118168 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 1,000 0,04594562 0,07113588 ! detection of stimulus GO:0051606 151 96 1,000 0,04594562 0,07109013 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 1,000 0,04680666 0,07237585 ! response to virus GO:0009615 160 98 1,000 0,04767362 0,07366907 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 1,000 0,04767362 0,07362178 ! rRNA transcription GO:0009303 25 14 0,000 0,04861712 0,07503066 ! lactation GO:0007595 26 14 0,000 0,04861712 0,07498256 ! reproductive cellular process GO:0048610 20 14 0,000 0,04861712 0,07493453 ! tRNA modification GO:0006400 20 14 0,000 0,04861712 0,07488656 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04861712 0,07483864 ! water transport GO:0006833 21 14 0,000 0,04861712 0,07479079 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04861712 0,074743 ! non-recombinational repair GO:0000726 25 14 0,000 0,04861712 0,07469527 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04861712 0,07464761 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04861712 0,0746 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04861712 0,07455245 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04861712 0,07450497 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04861712 0,07445754 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04861712 0,07441018 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04861712 0,07436287 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04861712 0,07431563 ! arginine metabolic process GO:0006525 17 14 0,000 0,04861712 0,07426844 ! regulation of heart rate GO:0002027 24 14 0,000 0,04861712 0,07422132 ! organic alcohol transport GO:0015850 29 14 0,000 0,04861712 0,07417425 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04861712 0,07412725 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04861712 0,0740803 ! embryo implantation GO:0007566 30 14 0,000 0,04861712 0,07403342 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04861712 0,07398659 ! L-amino acid transport GO:0015807 30 14 0,000 0,04861712 0,07393982 ! bone mineralization GO:0030282 17 14 0,000 0,04861712 0,07389311 ! stem cell development GO:0048864 43 14 0,000 0,04861712 0,07384646 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04861712 0,07379987 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04861712 0,07375334 ! cerebellum development GO:0021549 21 14 0,000 0,04861712 0,07370687 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04861712 0,07366045 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04861712 0,0736141 ! cofactor transport GO:0051181 26 14 0,000 0,04861712 0,0735678 ! NADP metabolic process GO:0006739 24 14 0,000 0,04861712 0,07352156 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04861712 0,07347538 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04861712 0,07342925 ! intestinal absorption GO:0050892 25 14 0,000 0,04861712 0,07338319 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04861712 0,07333718 ! oxygen transport GO:0015671 21 14 0,000 0,04861712 0,07329123 ! male genitalia development GO:0030539 24 14 0,000 0,04861712 0,07324533 ! regulation of RNA stability GO:0043487 32 14 0,000 0,04861712 0,0731995 ! regulation of axon extension GO:0030516 37 14 0,000 0,04861712 0,07315372 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04861712 0,073108 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05199878 0,07814432 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05199878 0,07809554 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,05199878 0,07804683 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,05199878 0,07799817 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05199878 0,07794957 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05199878 0,07790103 ! copper ion transport GO:0006825 20 15 0,000 0,05199878 0,07785256 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05199878 0,07780414 ! sulfate transport GO:0008272 23 15 0,000 0,05199878 0,07775579 ! response to cAMP GO:0051591 22 15 0,000 0,05199878 0,07770749 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05199878 0,07765926 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05199878 0,07761108 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05199878 0,07756296 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05199878 0,07751491 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05199878 0,07746691 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05199878 0,07741897 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05199878 0,0773711 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05199878 0,07732328 ! pituitary gland development GO:0021983 29 15 0,000 0,05199878 0,07727552 ! vesicle coating GO:0006901 33 15 0,000 0,05199878 0,07722782 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05199878 0,07718017 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05199878 0,07713259 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05199878 0,07708507 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05199878 0,0770376 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05199878 0,07699019 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05199878 0,07694284 ! histone deacetylation GO:0016575 20 15 0,000 0,05199878 0,07689555 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05199878 0,07684832 ! tissue regeneration GO:0042246 26 15 0,000 0,05199878 0,07680114 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05199878 0,07675403 ! water homeostasis GO:0030104 27 15 0,000 0,05199878 0,07670697 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05199878 0,07665996 ! muscle maintenance GO:0046716 26 15 0,000 0,05199878 0,07661302 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05199878 0,07656613 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05199878 0,0765193 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05199878 0,07647253 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05199878 0,07642582 ! cell killing GO:0001906 29 15 0,000 0,05199878 0,07637916 ! detection of bacterium GO:0016045 18 15 0,000 0,05199878 0,07633256 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05199878 0,07628601 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05199878 0,07623953 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05199878 0,07619309 ! peptide hormone processing GO:0016486 23 15 0,000 0,05199878 0,07614672 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,05536853 0,08103204 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05536853 0,08098278 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05536853 0,08093358 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05536853 0,08088444 ! filopodium assembly GO:0046847 32 16 0,000 0,05536853 0,08083536 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,05536853 0,08078634 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05536853 0,08073738 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05536853 0,08068848 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,05536853 0,08063963 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05536853 0,08059085 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,05536853 0,08054212 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05536853 0,08049346 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,05536853 0,08044485 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05536853 0,0803963 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05536853 0,08034781 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05536853 0,08029938 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05536853 0,08025101 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05536853 0,08020269 ! response to osmotic stress GO:0006970 25 16 0,000 0,05536853 0,08015444 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,05536853 0,08010624 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,05536853 0,0800581 ! fructose metabolic process GO:0006000 25 16 0,000 0,05536853 0,08001001 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05536853 0,07996199 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,05536853 0,07991402 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,05536853 0,07986611 ! axon cargo transport GO:0008088 43 16 0,000 0,05536853 0,07981826 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05536853 0,07977046 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05536853 0,07972273 ! DNA replication initiation GO:0006270 27 16 0,000 0,05536853 0,07967504 ! neuron recognition GO:0008038 35 16 0,000 0,05536853 0,07962742 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05536853 0,07957985 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05536853 0,07953234 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05536853 0,07948489 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05536853 0,07943749 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,05536853 0,07939015 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05536853 0,07934287 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05536853 0,07929564 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05536853 0,07924847 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05536853 0,07920135 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05536853 0,07915429 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,05536853 0,07910729 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05872641 0,08385504 ! metencephalon development GO:0022037 30 17 0,000 0,05872641 0,0838053 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05872641 0,08375562 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05872641 0,083706 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05872641 0,08365644 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05872641 0,08360694 ! signal complex assembly GO:0007172 41 17 0,000 0,05872641 0,0835575 ! endothelial cell migration GO:0043542 28 17 0,000 0,05872641 0,08350812 ! inositol metabolic process GO:0006020 28 17 0,000 0,05872641 0,08345879 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05872641 0,08340952 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05872641 0,08336032 ! glial cell development GO:0021782 27 17 0,000 0,05872641 0,08331116 ! limbic system development GO:0021761 36 17 0,000 0,05872641 0,08326207 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05872641 0,08321304 ! adult walking behavior GO:0007628 33 17 0,000 0,05872641 0,08316406 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05872641 0,08311514 ! heart looping GO:0001947 30 17 0,000 0,05872641 0,08306628 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05872641 0,08301747 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05872641 0,08296872 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05872641 0,08292003 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,05872641 0,0828714 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05872641 0,08282282 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05872641 0,0827743 ! glycine metabolic process GO:0006544 28 17 0,000 0,05872641 0,08272584 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05872641 0,08267743 ! NAD metabolic process GO:0019674 29 17 0,000 0,05872641 0,08262908 ! membrane budding GO:0006900 37 17 0,000 0,05872641 0,08258079 ! DNA integration GO:0015074 29 17 0,000 0,05872641 0,08253256 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05872641 0,08248438 ! regulation of protein binding GO:0043393 33 17 0,000 0,05872641 0,08243625 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05872641 0,08238818 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05872641 0,08234017 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05872641 0,08229222 ! genitalia development GO:0048806 30 17 0,000 0,05872641 0,08224432 ! neural crest cell migration GO:0001755 37 17 0,000 0,05872641 0,08219647 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05872641 0,08214868 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05872641 0,08210095 ! steroid catabolic process GO:0006706 31 17 0,000 0,05872641 0,08205327 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05872641 0,08200565 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05872641 0,08195808 ! gas transport GO:0015669 25 17 0,000 0,05872641 0,08191057 ! organic cation transport GO:0015695 31 17 0,000 0,05872641 0,08186311 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05872641 0,08181571 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05872641 0,08176836 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05872641 0,08172107 ! microspike assembly GO:0030035 36 17 0,000 0,05872641 0,08167384 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05872641 0,08162665 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06207246 0,08622768 ! neuron maturation GO:0042551 42 18 0,000 0,06207246 0,08617793 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06207246 0,08612823 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,06207246 0,08607858 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,06207246 0,086029 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06207246 0,08597947 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06207246 0,08593 ! memory GO:0007613 31 18 0,000 0,06207246 0,08588059 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06207246 0,08583123 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06207246 0,08578193 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,06207246 0,08573269 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,06207246 0,0856835 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,06207246 0,08563437 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06207246 0,0855853 ! response to retinoic acid GO:0032526 26 18 0,000 0,06207246 0,08553628 ! response to fungus GO:0009620 21 18 0,000 0,06207246 0,08548732 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,06207246 0,08543841 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,06207246 0,08538956 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06207246 0,08534077 ! vitamin transport GO:0051180 27 18 0,000 0,06207246 0,08529203 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06207246 0,08524335 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,06207246 0,08519472 ! nerve development GO:0021675 28 18 0,000 0,06207246 0,08514615 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06207246 0,08509763 ! protein secretion GO:0009306 39 19 0,000 0,06540673 0,08961766 ! positive regulation of translation GO:0045727 30 19 0,000 0,06540673 0,08956665 ! negative regulation of defense response GO:0031348 25 19 0,000 0,06540673 0,0895157 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,06540673 0,08946481 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,06540673 0,08941398 ! skin development GO:0043588 36 19 0,000 0,06540673 0,0893632 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,06540673 0,08931249 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06540673 0,08926183 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,06540673 0,08921123 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,06540673 0,08916068 ! bile acid metabolic process GO:0008206 29 19 0,000 0,06540673 0,08911019 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,06540673 0,08905976 ! cerebral cortex development GO:0021987 36 19 0,000 0,06540673 0,08900939 ! response to vitamin A GO:0033189 27 19 0,000 0,06540673 0,08895907 ! heme metabolic process GO:0042168 36 19 0,000 0,06540673 0,08890881 ! neuromuscular junction development GO:0007528 34 19 0,000 0,06540673 0,08885861 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,06540673 0,08880847 ! plasma membrane fusion GO:0045026 28 19 0,000 0,06540673 0,08875838 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,06540673 0,08870834 ! peptide cross-linking GO:0018149 37 19 0,000 0,06540673 0,08865837 ! protein export from nucleus GO:0006611 36 19 0,000 0,06540673 0,08860845 ! heart process GO:0003015 30 19 0,000 0,06540673 0,08855858 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,06540673 0,08850878 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,06540673 0,08845902 ! cellular pigmentation GO:0033059 36 19 0,000 0,06540673 0,08840933 ! cell-cell junction organization GO:0045216 35 19 0,000 0,06540673 0,08835969 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,06540673 0,0883101 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,06540673 0,08826057 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,06540673 0,0882111 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,06540673 0,08816168 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,06540673 0,08811232 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,06540673 0,08806301 ! cilium assembly GO:0042384 37 19 0,000 0,06540673 0,08801376 ! peptide hormone secretion GO:0030072 31 19 0,000 0,06540673 0,08796456 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06872926 0,09238134 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,06872926 0,09232976 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06872926 0,09227824 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06872926 0,09222677 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06872926 0,09217537 ! response to vitamin GO:0033273 31 20 0,000 0,06872926 0,09212402 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06872926 0,09207272 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,06872926 0,09202148 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06872926 0,0919703 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06872926 0,09191918 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,06872926 0,09186812 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06872926 0,09181711 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06872926 0,09176615 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,06872926 0,09171526 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06872926 0,09166442 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06872926 0,09161363 ! body fluid secretion GO:0007589 31 20 0,000 0,06872926 0,09156291 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,06872926 0,09151223 ! peptide secretion GO:0002790 35 20 0,000 0,06872926 0,09146162 ! stem cell differentiation GO:0048863 53 20 0,000 0,06872926 0,09141106 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06872926 0,09136056 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,06872926 0,09131011 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06872926 0,09125972 ! sensory perception of pain GO:0019233 30 20 0,000 0,06872926 0,09120938 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,06872926 0,0911591 ! diencephalon development GO:0021536 34 20 0,000 0,06872926 0,09110887 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06872926 0,0910587 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,06872926 0,09100859 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06872926 0,09095853 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06872926 0,09090853 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06872926 0,09085858 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06872926 0,09080868 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06872926 0,09075884 ! regulation of glucose import GO:0046324 29 20 0,000 0,06872926 0,09070906 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06872926 0,09065932 ! actin filament-based movement GO:0030048 43 20 0,000 0,06872926 0,09060965 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,06872926 0,09056003 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,06872926 0,09051046 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,06872926 0,09046094 ! negative regulation of translation GO:0017148 29 20 0,000 0,06872926 0,09041149 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,06872926 0,09036208 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,07204009 0,09466328 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,07204009 0,0946116 ! hormone secretion GO:0046879 38 21 0,000 0,07204009 0,09455999 ! glycerol metabolic process GO:0006071 34 21 0,000 0,07204009 0,09450843 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,07204009 0,09445693 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,07204009 0,09440548 ! axis specification GO:0009798 38 21 0,000 0,07204009 0,09435409 ! ovarian follicle development GO:0001541 35 21 0,000 0,07204009 0,09430275 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,07204009 0,09425147 ! smooth muscle contraction GO:0006939 46 21 0,000 0,07204009 0,09420025 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,07204009 0,09414908 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,07204009 0,09409797 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,07204009 0,09404691 ! cytolysis GO:0019835 24 21 0,000 0,07204009 0,09399591 ! vasodilation GO:0042311 39 21 0,000 0,07204009 0,09394496 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,07204009 0,09389407 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,07204009 0,09384324 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,07204009 0,09379246 ! oogenesis GO:0048477 36 21 0,000 0,07204009 0,09374173 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,07204009 0,09369106 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of biotic stimulus GO:0009595 29 21 0,000 0,07204009 0,09364044 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,07204009 0,09358988 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,07204009 0,09353937 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,07204009 0,09348892 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,07204009 0,09343852 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,07204009 0,09338818 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,07204009 0,09333789 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,07204009 0,09328765 ! collagen catabolic process GO:0030574 28 21 0,000 0,07204009 0,09323747 ! sperm-egg recognition GO:0035036 21 21 0,000 0,07204009 0,09318734 ! gut development GO:0048565 39 21 0,000 0,07204009 0,09313727 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,07533926 0,0973503 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,07533926 0,09729804 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,07533926 0,09724584 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,07533926 0,0971937 ! microtubule-based transport GO:0010970 54 22 0,000 0,07533926 0,09714161 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,07533926 0,09708958 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,07533926 0,09703761 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,07533926 0,09698569 ! regeneration GO:0031099 41 22 0,000 0,07533926 0,09693382 ! keratinization GO:0031424 28 22 0,000 0,07533926 0,09688202 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,07533926 0,09683026 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,07533926 0,09677856 ! sensory perception of taste GO:0050909 28 22 0,000 0,07533926 0,09672692 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,07533926 0,09667533 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,07533926 0,0966238 ! vacuolar transport GO:0007034 36 22 0,000 0,07533926 0,09657232 ! lysosome organization GO:0007040 41 22 0,000 0,07533926 0,0965209 ! central nervous system neuron development GO:0021954 46 22 0,000 0,07533926 0,09646953 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,07533926 0,09641822 ! fucose metabolic process GO:0006004 39 22 0,000 0,07533926 0,09636696 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,07533926 0,09631576 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,07533926 0,09626461 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,07533926 0,09621351 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,07533926 0,09616247 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,07533926 0,09611148 ! sarcomere organization GO:0045214 30 22 0,000 0,07533926 0,09606055 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,07533926 0,09600967 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,07533926 0,09595884 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,07533926 0,09590807 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,07533926 0,09585735 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,07533926 0,09580669 ! protein stabilization GO:0050821 39 22 0,000 0,07533926 0,09575608 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,0786268 0,09988178 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,0786268 0,09982907 ! gluconeogenesis GO:0006094 33 23 0,000 0,0786268 0,09977642 ! viral genome replication GO:0019079 41 23 0,000 0,0786268 0,09972382 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0786268 0,09967128 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0786268 0,09961879 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,0786268 0,09956636 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0786268 0,09951399 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0786268 0,09946167 ! visual behavior GO:0007632 42 23 0,000 0,0786268 0,0994094 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,0786268 0,09935719 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,0786268 0,09930503 ! peroxisome organization GO:0007031 37 23 0,000 0,0786268 0,09925293 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0786268 0,09920089 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,0786268 0,09914889 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,0786268 0,09909696 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0786268 0,09904507 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,0786268 0,09899324 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,0786268 0,09894147 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0786268 0,09888975 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0786268 0,09883808 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0786268 0,09878647 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0786268 0,09873491 ! fatty acid transport GO:0015908 44 23 0,000 0,0786268 0,09868341 ! platelet activation GO:0030168 37 23 0,000 0,0786268 0,09863195 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0786268 0,09858056 ! hormone transport GO:0009914 40 23 0,000 0,0786268 0,09852921 ! cell-cell recognition GO:0009988 25 23 0,000 0,0786268 0,09847792 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0786268 0,09842668 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0786268 0,0983755 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,0786268 0,09832437 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0786268 0,09827329 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,0786268 0,09822227 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,08190277 0,10226158 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,08190277 0,10220854 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,08190277 0,10215555 ! vesicle docking GO:0048278 47 24 0,000 0,08190277 0,10210262 ! spinal cord development GO:0021510 47 24 0,000 0,08190277 0,10204975 ! vacuole organization GO:0007033 43 24 0,000 0,08190277 0,10199693 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,08190277 0,10194416 ! digestive system process GO:0022600 39 24 0,000 0,08190277 0,10189145 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,08190277 0,10183879 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,08190277 0,10178619 ! regulation of behavior GO:0050795 43 24 0,000 0,08190277 0,10173364 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,08190277 0,10168115 ! membrane depolarization GO:0051899 39 24 0,000 0,08190277 0,10162871 ! pallium development GO:0021543 49 24 0,000 0,08190277 0,10157632 ! pentose metabolic process GO:0019321 35 24 0,000 0,08190277 0,10152399 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,08190277 0,10147171 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,08190277 0,10141949 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,08190277 0,10136732 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,08190277 0,1013152 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,08190277 0,10126314 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,08190277 0,10121113 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,08190277 0,10115917 ! regulation of amine transport GO:0051952 40 24 0,000 0,08190277 0,10110727 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,0851672 0,10508322 ! myelination GO:0042552 45 25 0,000 0,0851672 0,10502936 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,0851672 0,10497555 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,0851672 0,1049218 ! phototransduction GO:0007602 33 25 0,000 0,0851672 0,1048681 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,0851672 0,10481446 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,0851672 0,10476088 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,0851672 0,10470735 ! receptor metabolic process GO:0043112 46 25 0,000 0,0851672 0,10465387 ! chromosome condensation GO:0030261 45 25 0,000 0,0851672 0,10460045 ! osteoblast differentiation GO:0001649 60 25 0,000 0,0851672 0,10454708 ! neural crest cell development GO:0014032 54 25 0,000 0,0851672 0,10449377 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,0851672 0,10444051 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,0851672 0,1043873 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,0851672 0,10433415 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,0851672 0,10428106 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,0851672 0,10422801 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,0851672 0,10417503 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,0851672 0,10412209 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,0851672 0,10406921 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,0851672 0,10401638 ! telomere organization GO:0032200 43 25 0,000 0,0851672 0,10396361 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,0851672 0,10391089 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,0851672 0,10385822 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,08842012 0,10777043 ! embryonic pattern specification GO:0009880 44 26 0,000 0,08842012 0,10771586 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,08842012 0,10766135 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,08842012 0,10760689 ! initiation of viral infection GO:0019059 57 26 0,000 0,08842012 0,10755249 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,08842012 0,10749814 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,08842012 0,10744385 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,08842012 0,10738961 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,08842012 0,10733543 ! tube lumen formation GO:0035148 50 26 0,000 0,08842012 0,1072813 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,08842012 0,10722723 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,08842012 0,10717321 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,08842012 0,10711924 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,08842012 0,10706533 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,08842012 0,10701148 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,08842012 0,10695768 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,08842012 0,10690393 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,08842012 0,10685024 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,08842012 0,1067966 ! blastocyst development GO:0001824 49 26 0,000 0,08842012 0,10674301 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,08842012 0,10668948 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,08842012 0,106636 ! neuron fate commitment GO:0048663 48 27 0,000 0,09166159 0,11048988 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,09166159 0,11043455 ! iron ion transport GO:0006826 59 27 0,000 0,09166159 0,11037928 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,09166159 0,11032406 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,09166159 0,1102689 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,09166159 0,11021379 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,09166159 0,11015874 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,09166159 0,11010374 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,09166159 0,1100488 ! autophagy GO:0006914 41 27 0,000 0,09166159 0,10999391 ! male gonad development GO:0008584 44 27 0,000 0,09166159 0,10993908 ! response to toxin GO:0009636 47 27 0,000 0,09166159 0,1098843 ! primary neural tube formation GO:0014020 51 27 0,000 0,09166159 0,10982958 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,09166159 0,10977491 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,09166159 0,1097203 ! glutathione metabolic process GO:0006749 39 27 0,000 0,09166159 0,10966574 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,09166159 0,10961123 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,09166159 0,10955678 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,09166159 0,10950238 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,09166159 0,10944804 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,09489164 0,11324866 ! circadian rhythm GO:0007623 50 28 0,000 0,09489164 0,11319251 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,09489164 0,11313642 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,09489164 0,11308038 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,09489164 0,1130244 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,09489164 0,11296848 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,09489164 0,11291261 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,09489164 0,11285679 ! lipid oxidation GO:0034440 43 28 0,000 0,09489164 0,11280103 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,09489164 0,11274533 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,09489164 0,11268968 ! translational initiation GO:0006413 65 29 0,000 0,09811031 0,11645457 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,09811031 0,11639715 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,09811031 0,11633978 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,09811031 0,11628247 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,09811031 0,11622522 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,09811031 0,11616802 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,09811031 0,11611088 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,09811031 0,11605379 ! cell fate determination GO:0001709 60 29 0,000 0,09811031 0,11599677 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,09811031 0,11593979 ! detection of light stimulus GO:0009583 38 29 0,000 0,09811031 0,11588288 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,09811031 0,11582601 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,09811031 0,11576921 ! tissue homeostasis GO:0001894 48 29 0,000 0,09811031 0,11571246 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,09811031 0,11565577 ! zinc ion transport GO:0006829 45 30 0,000 0,10131765 0,11937819 ! membrane docking GO:0022406 61 30 0,000 0,10131765 0,11931975 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,10131765 0,11926138 ! regulation of innate immune response GO:0045088 51 30 0,000 0,10131765 0,11920306 ! acute-phase response GO:0006953 49 30 0,000 0,10131765 0,1191448 ! myofibril assembly GO:0030239 47 30 0,000 0,10131765 0,11908659 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,10131765 0,11902845 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,10131765 0,11897036 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,10131765 0,11891232 ! phospholipid transport GO:0015914 51 30 0,000 0,10131765 0,11885434 ! ensheathment of neurons GO:0007272 57 30 0,000 0,10131765 0,11879642 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,10131765 0,11873856 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,10131765 0,11868075 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,10131765 0,118623 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,10131765 0,1185653 ! eye morphogenesis GO:0048592 60 30 0,000 0,10131765 0,11850766 ! response to heat GO:0009408 50 30 0,000 0,10131765 0,11845008 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,10451368 0,1221272 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,10451368 0,12206792 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,10451368 0,12200869 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,10451368 0,12194952 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,10451368 0,12189041 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,10451368 0,12183135 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,10451368 0,12177235 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,10451368 0,12171341 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,10451368 0,12165453 ! ovulation cycle process GO:0022602 49 31 0,000 0,10451368 0,1215957 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,10451368 0,12153693 ! peptide transport GO:0015833 55 31 0,000 0,10451368 0,12147822 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,10451368 0,12141956 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,10451368 0,12136096 ! mesoderm formation GO:0001707 69 31 0,000 0,10451368 0,12130242 ! natural killer cell activation GO:0030101 45 31 0,000 0,10451368 0,12124393 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,10451368 0,1211855 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,10451368 0,12112712 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,10451368 0,12106881 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,10769845 0,12469801 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,10769845 0,12463803 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,10769845 0,12457811 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,10769845 0,12451825 ! cholesterol transport GO:0030301 56 32 0,000 0,10769845 0,12445844 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,10769845 0,12439869 ! spliceosome assembly GO:0000245 67 32 0,000 0,10769845 0,124339 ! spindle organization GO:0007051 46 32 0,000 0,10769845 0,12427936 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,10769845 0,12421978 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,10769845 0,12416026 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,10769845 0,1241008 ! muscle cell development GO:0055001 49 32 0,000 0,10769845 0,12404139 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,10769845 0,12398204 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,10769845 0,12392275 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,10769845 0,12386351 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,10769845 0,12380433 ! ovulation cycle GO:0042698 51 32 0,000 0,10769845 0,12374521 ! peripheral nervous system development GO:0007422 64 32 0,000 0,10769845 0,12368614 ! hindbrain development GO:0030902 61 32 0,000 0,10769845 0,12362713 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,10769845 0,12356818 ! gene silencing GO:0016458 65 32 0,000 0,10769845 0,12350928 ! post-embryonic development GO:0009791 69 33 0,000 0,110872 0,12708815 ! protein targeting to membrane GO:0006612 68 33 0,000 0,110872 0,12702763 ! ceramide metabolic process GO:0006672 64 33 0,000 0,110872 0,12696717 ! formation of primary germ layer GO:0001704 72 33 0,000 0,110872 0,12690677 ! cell fate specification GO:0001708 52 33 0,000 0,110872 0,12684643 ! sterol transport GO:0015918 57 33 0,000 0,110872 0,12678614 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,110872 0,12672591 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,110872 0,12666573 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,110872 0,12660562 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,11403437 0,13015498 ! glial cell differentiation GO:0010001 63 34 0,000 0,11403437 0,13009326 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,11403437 0,13003161 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,11403437 0,12997001 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,11403437 0,12990847 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,11403437 0,12984699 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,11403437 0,12978557 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,11403437 0,1297242 ! mismatch repair GO:0006298 46 34 0,000 0,11403437 0,1296629 ! spermatid development GO:0007286 63 34 0,000 0,11403437 0,12960165 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,11403437 0,12954046 ! placenta development GO:0001890 53 34 0,000 0,11403437 0,12947933 ! regulation of muscle development GO:0048634 70 35 0,000 0,11718559 0,13299459 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,11718559 0,13293189 ! negative regulation of secretion GO:0051048 63 35 0,000 0,11718559 0,13286925 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,11718559 0,13280666 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,11718559 0,13274413 ! female gonad development GO:0008585 58 35 0,000 0,11718559 0,13268167 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,11718559 0,13261926 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,11718559 0,13255691 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,11718559 0,13249461 ! cytokine production GO:0001816 59 35 0,000 0,11718559 0,13243238 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,11718559 0,13237021 ! vesicle localization GO:0051648 64 35 0,000 0,11718559 0,13230809 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,12032572 0,13578972 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,12032572 0,13572605 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,12032572 0,13566245 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,12032572 0,13559891 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,12032572 0,13553543 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,12032572 0,135472 ! regulation of proteolysis GO:0030162 72 36 0,000 0,12032572 0,13540864 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,12032572 0,13534534 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,12032572 0,13528209 ! aerobic respiration GO:0009060 55 36 0,000 0,12032572 0,1352189 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,12032572 0,13515578 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,12032572 0,13509271 ! RNA export from nucleus GO:0006405 56 37 0,000 0,12345477 0,13854113 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,12345477 0,13847654 ! meiosis I GO:0007127 65 37 0,000 0,12345477 0,13841201 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,12345477 0,13834755 ! sister chromatid segregation GO:0000819 58 37 0,000 0,12345477 0,13828314 ! actomyosin structure organization GO:0031032 62 37 0,000 0,12345477 0,13821879 ! organic anion transport GO:0015711 68 37 0,000 0,12345477 0,1381545 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,12345477 0,13809028 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,12345477 0,13802611 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,12345477 0,137962 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,12345477 0,13789795 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,12345477 0,13783396 ! pigment metabolic process GO:0042440 80 37 0,000 0,12345477 0,13777003 ! spermatid differentiation GO:0048515 66 37 0,000 0,12345477 0,13770616 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,1265728 0,1411187 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,1265728 0,14105334 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,1265728 0,14098804 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,1265728 0,1409228 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,1265728 0,14085761 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,1265728 0,14079249 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,1265728 0,14072743 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,1265728 0,14066243 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,1265728 0,14059749 ! mRNA catabolic process GO:0006402 71 39 0,000 0,12967984 0,14398233 ! learning GO:0007612 77 39 0,000 0,12967984 0,14391592 ! organic ether metabolic process GO:0018904 55 39 0,000 0,12967984 0,14384956 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,12967984 0,14378327 ! ion transmembrane transport GO:0034220 66 39 0,000 0,12967984 0,14371705 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,12967984 0,14365088 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,12967984 0,14358477 ! RNA modification GO:0009451 57 39 0,000 0,12967984 0,14351872 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,12967984 0,14345274 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,13277594 0,14681016 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,13277594 0,14674272 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,13277594 0,14667535 ! feeding behavior GO:0007631 59 40 0,000 0,13277594 0,14660803 ! negative regulation of binding GO:0051100 72 40 0,000 0,13277594 0,14654078 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,13277594 0,14647359 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,13277594 0,14640646 ! maintenance of protein location GO:0045185 91 40 0,000 0,13277594 0,1463394 ! cytokinesis GO:0000910 72 40 0,000 0,13277594 0,14627239 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,13586112 0,14960268 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,13586112 0,14953424 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,13586112 0,14946587 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,13586112 0,14939755 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,13586112 0,1493293 ! female gamete generation GO:0007292 61 41 0,000 0,13586112 0,14926112 ! polyol metabolic process GO:0019751 66 41 0,000 0,13586112 0,14919299 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,13893542 0,15249938 ! regulation of tube size GO:0035150 71 42 0,000 0,13893542 0,15242984 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,13893542 0,15236036 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,13893542 0,15229095 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,13893542 0,1522216 ! neuron migration GO:0001764 79 42 0,000 0,13893542 0,15215231 ! regulation of protein secretion GO:0050708 71 42 0,000 0,13893542 0,15208309 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,13893542 0,15201393 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,1419989 0,15529516 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,1419989 0,1552246 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,1419989 0,15515411 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,1419989 0,15508368 ! striated muscle contraction GO:0006941 77 43 0,000 0,1419989 0,15501331 ! phagocytosis GO:0006909 90 43 0,000 0,1419989 0,15494301 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,1419989 0,15487278 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,14505157 0,15813053 ! male sex differentiation GO:0046661 76 44 0,000 0,14505157 0,15805891 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,14505157 0,15798736 ! developmental growth GO:0048589 82 44 0,000 0,14505157 0,15791587 ! maintenance of location in cell GO:0051651 97 44 0,000 0,14505157 0,15784445 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,14809348 0,16108179 ! glycolysis GO:0006096 65 45 0,000 0,14809348 0,161009 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,14809348 0,16093628 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,14809348 0,16086362 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,14809348 0,16079103 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,14809348 0,1607185 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,14809348 0,16064604 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,14809348 0,16057365 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,15112468 0,16378647 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,15112468 0,16371273 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,15112468 0,16363905 ! positive regulation of defense response GO:0031349 76 47 0,000 0,15414518 0,1668346 ! endosome transport GO:0016197 108 47 0,000 0,15414518 0,16675958 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,15414518 0,16668463 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,15414518 0,16660975 ! JNK cascade GO:0007254 91 47 0,000 0,15414518 0,16653494 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,15414518 0,16646019 ! Notch signaling pathway GO:0007219 96 48 0,000 0,15715504 0,16963438 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,15715504 0,16955831 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,15715504 0,16948231 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,15715504 0,16940638 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,16015429 0,17256212 ! regulation of action potential GO:0001508 95 49 0,000 0,16015429 0,17248488 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,16015429 0,17240771 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,16015429 0,1723306 ! regulation of ion transport GO:0043269 77 49 0,000 0,16015429 0,17225356 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,16015429 0,1721766 ! peptide metabolic process GO:0006518 76 49 0,000 0,16015429 0,1720997 ! response to temperature stimulus GO:0009266 76 49 0,000 0,16015429 0,17202287 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,16015429 0,17194611 ! endocrine system development GO:0035270 104 49 0,000 0,16015429 0,17186941 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,16015429 0,17179279 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,16015429 0,17171623 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,16015429 0,17163974 ! inner ear development GO:0048839 79 50 0,000 0,16314297 0,1747649 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,16314297 0,17468713 ! viral infectious cycle GO:0019058 99 51 0,000 0,1661211 0,17779688 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,1661211 0,17771782 ! excretion GO:0007588 83 51 0,000 0,1661211 0,17763883 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,1661211 0,17755992 ! chromatin remodeling GO:0006338 109 51 0,000 0,1661211 0,17748107 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,1661211 0,1774023 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,1661211 0,17732359 ! vesicle organization GO:0016050 107 51 0,000 0,1661211 0,17724496 ! regulation of cell shape GO:0008360 125 51 0,000 0,1661211 0,17716639 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,16908874 0,18025145 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,16908874 0,18017162 ! membrane fusion GO:0006944 110 52 0,000 0,16908874 0,18009186 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,17204592 0,18316039 ! RNA catabolic process GO:0006401 93 53 0,000 0,17204592 0,18307938 ! regulation of translational initiation GO:0006446 82 53 0,000 0,17204592 0,18299845 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,17204592 0,18291758 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,17204592 0,18283679 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,17204592 0,18275606 ! cell maturation GO:0048469 100 53 0,000 0,17204592 0,18267541 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,17204592 0,18259483 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,17499267 0,18564037 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,17499267 0,18555856 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,17499267 0,18547681 ! cell recognition GO:0008037 85 54 0,000 0,17499267 0,18539514 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,17499267 0,18531354 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,17499267 0,18523201 ! chloride transport GO:0006821 90 55 0,000 0,17792903 0,18825736 ! glucose catabolic process GO:0006007 82 55 0,000 0,17792903 0,18817461 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,17792903 0,18809194 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,17792903 0,18800933 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,17792903 0,1879268 ! gastrulation GO:0007369 112 55 0,000 0,17792903 0,18784434 ! RNA elongation GO:0006354 79 55 0,000 0,17792903 0,18776195 ! nuclear export GO:0051168 97 55 0,000 0,17792903 0,18767963 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,17792903 0,18759739 ! regulation of actin filament length GO:0030832 105 56 0,000 0,18085504 0,19059887 ! sensory perception of smell GO:0007608 80 56 0,000 0,18085504 0,19051542 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,18085504 0,19043204 ! proton transport GO:0015992 94 56 0,000 0,18085504 0,19034874 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,18085504 0,19026551 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,18377072 0,19324841 ! maintenance of location GO:0051235 118 57 0,000 0,18377072 0,19316399 ! hydrogen transport GO:0006818 97 58 0,000 0,18667613 0,19613221 ! regulation of endocytosis GO:0030100 91 58 0,000 0,18667613 0,1960466 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,18667613 0,19596107 ! positive regulation of secretion GO:0051047 95 59 0,000 0,18957129 0,19891345 ! regulation of cellular component size GO:0032535 109 59 0,000 0,18957129 0,19882673 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,18957129 0,1987401 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,18957129 0,19865354 ! establishment of organelle localization GO:0051656 109 59 0,000 0,18957129 0,19856706 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,19245624 0,20150118 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,19245624 0,20141354 ! camera-type eye development GO:0043010 116 60 0,000 0,19245624 0,20132597 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,19533102 0,20424443 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,19533102 0,20415571 ! mesoderm development GO:0007498 119 61 0,000 0,19533102 0,20406706 ! tRNA processing GO:0008033 89 61 0,000 0,19533102 0,20397849 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,19533102 0,20388999 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,19819566 0,20679044 ! gonad development GO:0008406 98 62 0,000 0,19819566 0,20670081 ! regulation of mitosis GO:0007088 105 63 0,000 0,2010502 0,20958699 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,2010502 0,20949622 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,2010502 0,20940553 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,20389466 0,21227631 ! cell redox homeostasis GO:0045454 102 64 0,000 0,20389466 0,2121845 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,20389466 0,21209276 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,20389466 0,21200111 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,20389466 0,21190953 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,2067291 0,21476261 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,2067291 0,21466992 ! germ cell development GO:0007281 118 65 0,000 0,2067291 0,21457731 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,20955354 0,21741518 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,20955354 0,21732147 ! secondary metabolic process GO:0019748 116 66 0,000 0,20955354 0,21722784 ! developmental maturation GO:0021700 116 66 0,000 0,20955354 0,21713428 ! cell projection assembly GO:0030031 120 66 0,000 0,20955354 0,21704081 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,21236801 0,2198612 ! chromosome segregation GO:0007059 113 67 0,000 0,21236801 0,21976664 ! hexose catabolic process GO:0019320 104 67 0,000 0,21236801 0,21967215 ! adaptive immune response GO:0002250 119 67 0,000 0,21236801 0,21957775 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! amino acid transport GO:0006865 125 68 0,000 0,21517256 0,22238195 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,21517256 0,22228646 ! regulation of lipase activity GO:0060191 130 68 0,000 0,21517256 0,22219106 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,21517256 0,22209574 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,21796721 0,22488384 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,21796721 0,22478744 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,21796721 0,22469113 ! antigen processing and presentation GO:0019882 104 69 0,000 0,21796721 0,22459491 ! amine catabolic process GO:0009310 117 71 0,000 0,22352697 0,23022513 ! reproductive structure development GO:0048608 113 71 0,000 0,22352697 0,23012662 ! humoral immune response GO:0006959 109 71 0,000 0,22352697 0,23002819 ! acute inflammatory response GO:0002526 113 72 0,000 0,22629215 0,23277423 ! learning or memory GO:0007611 147 73 0,000 0,22904758 0,2355079 ! regulation of blood pressure GO:0008217 125 73 0,000 0,22904758 0,23540729 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,22904758 0,23530678 ! axon guidance GO:0007411 139 73 0,000 0,22904758 0,23520635 ! fertilization GO:0009566 90 73 0,000 0,22904758 0,23510601 ! transition metal ion transport GO:0000041 126 74 0,000 0,23179328 0,23782287 ! neurotransmitter transport GO:0006836 123 74 0,000 0,23179328 0,2377215 ! meiosis GO:0007126 121 74 0,000 0,23179328 0,23762021 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,23179328 0,23751901 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,23179328 0,2374179 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,23179328 0,23731687 ! organelle localization GO:0051640 136 74 0,000 0,23179328 0,23721592 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,2345293 0,2399139 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,2345293 0,23981194 ! meiotic cell cycle GO:0051321 122 75 0,000 0,2345293 0,23971006 ! rhythmic process GO:0048511 128 75 0,000 0,2345293 0,23960828 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,23725566 0,2422908 ! defense response to bacterium GO:0042742 89 76 0,000 0,23725566 0,242188 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,23725566 0,24208529 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,23725566 0,24198267 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,2399724 0,24464983 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,2399724 0,24454621 ! blood coagulation GO:0007596 146 78 0,000 0,24267956 0,24720026 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,24267956 0,24709565 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,24267956 0,24699112 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,24537716 0,24963106 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,24806524 0,25225908 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,24806524 0,2521525 ! inorganic anion transport GO:0015698 138 80 0,000 0,24806524 0,25204602 ! digestion GO:0007586 112 81 0,000 0,25074384 0,25466006 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,25074384 0,25455261 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,25341299 0,25715379 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,25341299 0,25704538 ! response to nutrient GO:0007584 125 82 0,000 0,25341299 0,25693706 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,25341299 0,25682883 ! regulation of lyase activity GO:0051339 160 83 0,000 0,25607271 0,25941513 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,25872305 0,26198975 ! hemostasis GO:0007599 158 84 0,000 0,25872305 0,26187953 ! negative regulation of transport GO:0051051 153 84 0,000 0,25872305 0,26176941 ! nucleosome assembly GO:0006334 122 85 0,000 0,26136403 0,26433033 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,26399569 0,26687968 ! chromatin assembly GO:0031497 124 86 0,000 0,26399569 0,26676759 ! alcohol catabolic process GO:0046164 130 86 0,000 0,26399569 0,2666556 ! amine transport GO:0015837 155 86 0,000 0,26399569 0,2665437 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,26661806 0,26907846 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,26661806 0,26896564 ! cellular respiration GO:0045333 135 88 0,000 0,26923118 0,27148794 ! cellular defense response GO:0006968 114 89 0,000 0,27183507 0,27399882 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,27442977 0,27649834 ! sex differentiation GO:0007548 145 90 0,000 0,27442977 0,2763826 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,27442977 0,27626696 ! sterol metabolic process GO:0016125 152 91 0,000 0,27701531 0,27875317 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,27701531 0,27863664 ! regulation of defense response GO:0031347 149 92 0,000 0,27959172 0,28111061 ! nucleosome organization GO:0034728 138 92 0,000 0,27959172 0,28099318 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,27959172 0,28087586 ! vitamin metabolic process GO:0006766 139 92 0,000 0,27959172 0,28075863 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,28215904 0,28321846 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,28215904 0,28310035 ! regulation of membrane potential GO:0042391 164 93 0,000 0,28215904 0,28298235 ! female pregnancy GO:0007565 164 94 0,000 0,28471729 0,28542909 ! forebrain development GO:0030900 188 95 0,000 0,28726651 0,28786474 ! protein ubiquitination GO:0016567 217 97 0,000 0,29233798 0,29282481 ! hormone metabolic process GO:0042445 157 97 0,000 0,29233798 0,29270295 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,2948603 0,2951056 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,2973737 0,29749735 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,2973737 0,2973737