pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1129-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interaction with host GO:0051701 66 25 4,000 6,938E-09 1,695E-05 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 4,000 3,564E-08 4,353E-05 ! positive regulation of glycolysis GO:0045821 13 5 2,000 1,962E-07 1,598E-04 ! nuclear migration GO:0007097 13 6 2,000 3,917E-07 2,392E-04 ! interaction with symbiont GO:0051702 14 6 2,000 3,917E-07 1,914E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 3,917E-07 1,595E-04 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of cell migration GO:0030335 137 58 4,000 5,573E-07 1,945E-04 ! positive regulation of cell motion GO:0051272 157 65 4,000 9,895E-07 3,022E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 1,092E-06 2,965E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 1,092E-06 2,669E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 1,092E-06 2,426E-04 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 1,635E-06 3,329E-04 ! regulation of glycolysis GO:0006110 20 9 2,000 1,635E-06 3,073E-04 ! macrophage differentiation GO:0030225 15 9 2,000 1,635E-06 2,854E-04 ! protein heterooligomerization GO:0051291 17 10 2,000 2,332E-06 3,797E-04 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 2,000 2,332E-06 3,56E-04 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 2,332E-06 3,351E-04 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 3,2E-06 4,343E-04 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 2,000 3,2E-06 4,114E-04 ! nucleus localization GO:0051647 22 11 2,000 3,2E-06 3,908E-04 ! positive regulation of cellular catabolic process GO:0031331 34 12 2,000 4,258E-06 4,953E-04 ! regulation of cell projection assembly GO:0060491 33 12 2,000 4,258E-06 4,728E-04 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 2,000 5,524E-06 5,867E-04 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 2,000 5,524E-06 5,623E-04 ! regulation of erythrocyte differentiation GO:0045646 47 13 2,000 5,524E-06 5,398E-04 ! regulation of RNA stability GO:0043487 33 14 2,000 7,017E-06 6,593E-04 ! cell killing GO:0001906 32 15 2,000 8,753E-06 7,92E-04 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 1,075E-05 9,381E-04 ! filopodium assembly GO:0046847 42 17 2,000 1,303E-05 1,098E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,561E-05 1,271E-03 ! DNA integration GO:0015074 32 18 2,000 1,561E-05 1,23E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 2,000 1,561E-05 1,191E-03 ! microspike assembly GO:0030035 46 18 2,000 1,561E-05 1,155E-03 ! regulation of carbohydrate metabolic process GO:0006109 37 20 2,000 2,172E-05 1,56E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 2,528E-05 1,765E-03 ! actin filament-based movement GO:0030048 47 21 2,000 2,528E-05 1,716E-03 ! DNA damage response, signal transduction GO:0042770 136 62 3,000 2,575E-05 1,7E-03 ! regulation of homeostatic process GO:0032844 148 62 3,000 2,575E-05 1,655E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 2,000 2,922E-05 1,83E-03 ! regulation of cellular catabolic process GO:0031329 55 24 2,000 3,825E-05 2,336E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 3,825E-05 2,279E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 4,338E-05 2,523E-03 ! organelle localization GO:0051640 155 74 3,000 5,179E-05 2,943E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 5,495E-05 3,051E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 5,495E-05 2,983E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 5,495E-05 2,918E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 6,142E-05 3,193E-03 ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 7,332E-05 3,731E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 7,332E-05 3,655E-03 ! parathyroid gland development GO:0060017 14 5 1,000 7,332E-05 3,582E-03 ! mRNA transcription GO:0009299 10 5 1,000 7,332E-05 3,512E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 7,332E-05 3,444E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 7,332E-05 3,379E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 7,332E-05 3,317E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 7,332E-05 3,257E-03 ! response to hypoxia GO:0001666 178 81 3,000 7,38E-05 3,22E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 7,582E-05 3,25E-03 ! response to oxygen levels GO:0070482 183 83 3,000 8,118E-05 3,419E-03 ! positive regulation of catabolic process GO:0009896 72 32 2,000 9,226E-05 3,82E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 1,098E-04 4,47E-03 ! embryonic hemopoiesis GO:0035162 16 6 1,000 1,098E-04 4,397E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 1,098E-04 4,326E-03 ! oxygen homeostasis GO:0032364 10 6 1,000 1,098E-04 4,257E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 1,098E-04 4,19E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,263E-04 4,748E-03 ! tissue remodeling GO:0048771 78 37 2,000 1,431E-04 5,297E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,534E-04 5,594E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,534E-04 5,512E-03 GO:0043489|RNA stabilization, ! male sex determination GO:0030238 15 7 1,000 1,534E-04 5,432E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 1,534E-04 5,354E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 1,551E-04 5,336E-03 ! carbohydrate homeostasis GO:0033500 59 39 2,000 1,677E-04 5,689E-03 GO:0042593|glucose homeostasis, ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 1,948E-04 6,519E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,042E-04 6,741E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 2,042E-04 6,651E-03 ! hemoglobin metabolic process GO:0020027 14 8 1,000 2,042E-04 6,564E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,042E-04 6,478E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,042E-04 6,395E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 2,042E-04 6,314E-03 ! gas homeostasis GO:0033483 14 8 1,000 2,042E-04 6,235E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 2,042E-04 6,158E-03 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 1,000 2,042E-04 6,083E-03 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 2,000 2,246E-04 6,611E-03 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 2,246E-04 6,533E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 2,572E-04 7,394E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 2,621E-04 7,444E-03 GO:0010469|regulation of receptor activity, ! induction of positive chemotaxis GO:0050930 17 9 1,000 2,621E-04 7,359E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 2,621E-04 7,275E-03 ! mitochondrion localization GO:0051646 18 9 1,000 2,621E-04 7,193E-03 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 2,747E-04 7,455E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 2,928E-04 7,861E-03 ! positive regulation of cell cycle GO:0045787 96 48 2,000 3,117E-04 8,277E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 3,27E-04 8,59E-03 ! lung alveolus development GO:0048286 26 10 1,000 3,27E-04 8,498E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 1,000 3,27E-04 8,409E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 3,27E-04 8,321E-03 ! regulation of cell projection organization GO:0031344 135 51 2,000 3,731E-04 9,396E-03 ! keratinocyte proliferation GO:0043616 19 11 1,000 3,99E-04 9,945E-03 ! blood vessel remodeling GO:0001974 30 11 1,000 3,99E-04 9,845E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 3,99E-04 9,746E-03 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 3,99E-04 9,65E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 3,99E-04 9,555E-03 ! thymus development GO:0048538 29 11 1,000 3,99E-04 9,463E-03 ! regulation of embryonic development GO:0045995 35 11 1,000 3,99E-04 9,372E-03 ! positive regulation of growth GO:0045927 96 53 2,000 4,18E-04 9,726E-03 ! regulation of angiogenesis GO:0045765 125 54 2,000 4,417E-04 0,01018092 ! virus-host interaction GO:0019048 30 12 1,000 4,779E-04 0,01091108 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 4,779E-04 0,01081005 GO:0050927|positive regulation of positive chemotaxis, ! entry into host cell GO:0030260 34 12 1,000 4,779E-04 0,01071087 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 4,779E-04 0,0106135 ! regulation of hormone metabolic process GO:0032350 28 12 1,000 4,779E-04 0,01051788 ! peptidyl-lysine modification GO:0018205 21 12 1,000 4,779E-04 0,01042397 ! regulation of leukocyte migration GO:0002685 29 12 1,000 4,779E-04 0,01033173 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 4,779E-04 0,0102411 ! embryonic placenta development GO:0001892 21 12 1,000 4,779E-04 0,01015204 ! localization within membrane GO:0051668 26 12 1,000 4,779E-04 0,01006453 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 5,18E-04 0,01081652 ! regulation of bone remodeling GO:0046850 143 57 2,000 5,18E-04 0,01072486 ! heart morphogenesis GO:0003007 105 57 2,000 5,18E-04 0,01063473 ! regulation of tissue remodeling GO:0034103 146 58 2,000 5,452E-04 0,01109943 ! regulation of chemokine production GO:0032642 18 13 1,000 5,638E-04 0,01138266 ! positive regulation of cell growth GO:0030307 24 13 1,000 5,638E-04 0,01128936 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 5,638E-04 0,01119757 ! regulation of mRNA stability GO:0043488 32 13 1,000 5,638E-04 0,01110727 ! establishment of organelle localization GO:0051656 122 59 2,000 5,733E-04 0,01120415 ! hair follicle morphogenesis GO:0031069 27 14 1,000 6,566E-04 0,01273012 ! negative regulation of caspase activity GO:0043154 23 14 1,000 6,566E-04 0,01262988 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 6,566E-04 0,01253121 ! viral reproductive process GO:0022415 132 62 2,000 6,63E-04 0,01255586 ! regulation of protein complex assembly GO:0043254 132 63 2,000 6,948E-04 0,01305646 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 7,275E-04 0,01356723 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 7,275E-04 0,01346445 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 7,562E-04 0,01389078 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 7,562E-04 0,01378711 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 7,562E-04 0,01368499 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 7,562E-04 0,01358436 ! muscle maintenance GO:0046716 26 15 1,000 7,562E-04 0,01348521 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 7,562E-04 0,01338749 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 7,959E-04 0,01398814 ! activation of MAPK activity GO:0000187 124 67 2,000 8,316E-04 0,0145106 ! myeloid cell differentiation GO:0030099 126 67 2,000 8,316E-04 0,01440769 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 8,627E-04 0,01484257 ! negative regulation of inflammatory response GO:0050728 24 16 1,000 8,627E-04 0,01473878 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 8,627E-04 0,01463643 ! positive regulation of cell size GO:0045793 29 16 1,000 8,627E-04 0,01453549 ! viral reproduction GO:0016032 142 68 2,000 8,682E-04 0,0145278 ! adaptive immune response GO:0002250 126 68 2,000 8,682E-04 0,01442898 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 2,000 8,682E-04 0,01433148 ! lung development GO:0030324 165 69 2,000 9,059E-04 0,01485305 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 9,76E-04 0,01589614 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 9,76E-04 0,01579086 ! complement activation, alternative pathway GO:0006957 19 17 1,000 9,76E-04 0,01568698 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 9,76E-04 0,01558445 ! respiratory tube development GO:0030323 171 72 2,000 1,025E-03 0,01626184 ! heart looping GO:0001947 34 18 1,000 1,096E-03 0,01727553 ! epidermis morphogenesis GO:0048730 43 18 1,000 1,096E-03 0,01716479 ! response to retinoic acid GO:0032526 31 18 1,000 1,096E-03 0,01705546 ! neural crest cell migration GO:0001755 41 18 1,000 1,096E-03 0,01694752 ! regulation of caspase activity GO:0043281 136 74 2,000 1,11E-03 0,0170522 ! respiratory system development GO:0060541 175 74 2,000 1,11E-03 0,01694562 ! negative regulation of defense response GO:0031348 27 19 1,000 1,223E-03 0,01855538 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 1,223E-03 0,01844084 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 1,223E-03 0,01832771 ! response to vitamin A GO:0033189 32 19 1,000 1,223E-03 0,01821595 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 1,223E-03 0,01810556 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 1,245E-03 0,01832238 ! regulation of catabolic process GO:0009894 173 77 2,000 1,245E-03 0,01821267 ! protein oligomerization GO:0051259 149 79 2,000 1,341E-03 0,01949474 ! positive regulation of angiogenesis GO:0045766 50 20 1,000 1,356E-03 0,01960626 ! skin development GO:0043588 42 20 1,000 1,356E-03 0,01949093 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,356E-03 0,01937694 ! protein amino acid acetylation GO:0006473 41 20 1,000 1,356E-03 0,01926429 ! response to vitamin GO:0033273 36 20 1,000 1,356E-03 0,01915293 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 1,356E-03 0,01904286 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 1,356E-03 0,01893404 ! regulation of peptidase activity GO:0052547 150 82 2,000 1,493E-03 0,02071696 ! lipid phosphorylation GO:0046834 43 21 1,000 1,496E-03 0,0206539 ! plasma membrane fusion GO:0045026 33 21 1,000 1,496E-03 0,02053787 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 1,496E-03 0,02042313 ! cellular response to starvation GO:0009267 37 22 1,000 1,643E-03 0,02230098 ! cytolysis GO:0019835 27 22 1,000 1,643E-03 0,02217777 ! positive regulation of locomotion GO:0040017 44 22 1,000 1,643E-03 0,02205591 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 1,000 1,643E-03 0,02193539 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 1,655E-03 0,02197074 ! positive regulation of DNA replication GO:0045740 44 23 1,000 1,796E-03 0,02372257 ! regulation of chemotaxis GO:0050920 45 23 1,000 1,796E-03 0,02359503 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 1,796E-03 0,02346886 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cell adhesion GO:0045785 61 24 1,000 1,956E-03 0,02542102 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 1,956E-03 0,02528652 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 1,956E-03 0,02515343 ! sex determination GO:0007530 48 24 1,000 1,956E-03 0,02502174 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 2,123E-03 0,02700789 ! vasculogenesis GO:0001570 49 25 1,000 2,123E-03 0,02686795 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 2,123E-03 0,02672946 ! regulation of behavior GO:0050795 48 25 1,000 2,123E-03 0,02659239 ! protein tetramerization GO:0051262 57 25 1,000 2,123E-03 0,02645671 ! initiation of viral infection GO:0019059 60 26 1,000 2,295E-03 0,02846537 ! molting cycle process GO:0022404 52 26 1,000 2,295E-03 0,02832161 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 2,295E-03 0,02817929 ! neural crest cell development GO:0014032 59 26 1,000 2,295E-03 0,02803839 GO:0014033|neural crest cell differentiation, ! positive regulation of nuclear division GO:0051785 41 26 1,000 2,295E-03 0,0278989 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 2,295E-03 0,02776078 ! response to starvation GO:0042594 47 27 1,000 2,475E-03 0,02978105 ! cellular response to oxidative stress GO:0034599 43 27 1,000 2,475E-03 0,02963506 ! cellular response to nutrient levels GO:0031669 45 27 1,000 2,475E-03 0,0294905 ! leukocyte differentiation GO:0002521 232 98 2,000 2,484E-03 0,02945706 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 2,484E-03 0,02931476 ! mRNA transport GO:0051028 185 100 2,000 2,63E-03 0,03089439 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 2,66E-03 0,03109595 ! protein amino acid acylation GO:0043543 59 28 1,000 2,66E-03 0,03094787 ! fat cell differentiation GO:0045444 57 28 1,000 2,66E-03 0,0308012 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 2,66E-03 0,03065591 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 2,852E-03 0,03271404 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 2,852E-03 0,03256118 ! somitogenesis GO:0001756 52 29 1,000 2,852E-03 0,03240973 ! complement activation, classical pathway GO:0006958 51 30 1,000 3,051E-03 0,03450269 ! iron ion homeostasis GO:0055072 60 31 1,000 3,255E-03 0,03664718 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 3,255E-03 0,03647907 ! collagen metabolic process GO:0032963 49 32 1,000 3,466E-03 0,03866472 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 3,466E-03 0,03848897 ! negative regulation of response to external stimulus GO:0032102 50 33 1,000 3,683E-03 0,0407145 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 3,683E-03 0,04053111 ! leukocyte chemotaxis GO:0030595 55 33 1,000 3,683E-03 0,04034935 GO:0060326|cell chemotaxis, ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 4,136E-03 0,0451063 ! calcium-mediated signaling GO:0019722 67 35 1,000 4,136E-03 0,04490583 ! placenta development GO:0001890 53 35 1,000 4,136E-03 0,04470713 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 4,371E-03 0,04704502 ! embryonic organ development GO:0048568 67 36 1,000 4,371E-03 0,04683868 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 4,613E-03 0,04921171 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 4,613E-03 0,04899775 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 4,861E-03 0,05140484 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 5,374E-03 0,0565887 GO:0006956|complement activation, ! gliogenesis GO:0042063 91 41 1,000 5,64E-03 0,05913062 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 5,64E-03 0,05887793 ! mesenchymal cell development GO:0014031 94 41 1,000 5,64E-03 0,05862738 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 6,188E-03 0,06406099 GO:0090047|positive regulation of transcription regulator activity, ! segmentation GO:0035282 78 43 1,000 6,188E-03 0,06379069 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 6,472E-03 0,06642996 ! receptor-mediated endocytosis GO:0006898 98 45 1,000 6,761E-03 0,06910654 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 6,761E-03 0,0688186 ! keratinocyte differentiation GO:0030216 81 45 1,000 6,761E-03 0,06853304 ! maintenance of location in cell GO:0051651 101 45 1,000 6,761E-03 0,06824985 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 7,056E-03 0,07093297 ! leukocyte migration GO:0050900 75 46 1,000 7,056E-03 0,07064226 ! negative regulation of cell migration GO:0030336 122 46 1,000 7,056E-03 0,07035393 ! positive regulation of DNA binding GO:0043388 83 48 1,000 7,662E-03 0,07609446 ! vascular process in circulatory system GO:0003018 85 48 1,000 7,662E-03 0,07578638 ! regulation of inflammatory response GO:0050727 84 48 1,000 7,662E-03 0,07548079 ! JNK cascade GO:0007254 106 49 1,000 7,974E-03 0,07823836 ! endocrine system development GO:0035270 109 50 1,000 8,292E-03 0,08102904 ! activation of caspase activity GO:0006919 95 50 1,000 8,292E-03 0,08070622 ! regulation of ossification GO:0030278 123 50 1,000 8,292E-03 0,08038595 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 8,292E-03 0,08006822 GO:0019724|B cell mediated immunity, ! epidermal cell differentiation GO:0009913 87 50 1,000 8,292E-03 0,07975299 ! positive regulation of cytokine production GO:0001819 94 50 1,000 8,292E-03 0,07944024 ! viral infectious cycle GO:0019058 104 51 1,000 8,615E-03 0,0822144 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 8,615E-03 0,0818945 ! positive regulation of binding GO:0051099 88 52 1,000 8,944E-03 0,08469049 ! excretion GO:0007588 87 52 1,000 8,944E-03 0,0843635 ! histone modification GO:0016570 104 52 1,000 8,944E-03 0,08403903 ! amino acid activation GO:0043038 98 52 1,000 8,944E-03 0,08371704 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 99 53 1,000 9,278E-03 0,08651514 ! activation of phospholipase C activity GO:0007202 110 54 1,000 9,618E-03 0,08934322 GO:0010863|positive regulation of phospholipase C activity, ! membrane fusion GO:0006944 122 54 1,000 9,618E-03 0,0890048 ! covalent chromatin modification GO:0016569 115 54 1,000 9,618E-03 0,08866893 ! regulation of cell shape GO:0008360 142 54 1,000 9,618E-03 0,08833559 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 9,964E-03 0,09116468 ! response to UV GO:0009411 120 55 1,000 9,964E-03 0,09082451 ! negative regulation of cell motion GO:0051271 142 55 1,000 9,964E-03 0,09048687 ! regulation of DNA replication GO:0006275 105 56 1,000 0,01031436 0,0933259 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,0106706 0,09619286 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,0106706 0,09583921 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,01103222 0,09872419 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,01103222 0,09836389 ! maintenance of location GO:0051235 124 58 1,000 0,01103222 0,0980062 ! lipid modification GO:0030258 112 60 1,000 0,01177151 0,10419488 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 0,01214911 0,10714901 ! regulation of mitosis GO:0007088 112 63 1,000 0,01292009 0,11353873 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 1,000 0,01292009 0,11313179 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01357155 0,11841175 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01357155 0,11799035 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01357155 0,11757195 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01357155 0,1171565 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01357155 0,11674398 ! neuron fate determination GO:0048664 7 5 0,000 0,01357155 0,11633435 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01357155 0,11592759 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01357155 0,11552366 ! polyol transport GO:0015791 12 5 0,000 0,01357155 0,11512253 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01357155 0,11472418 ! response to superoxide GO:0000303 10 5 0,000 0,01357155 0,11432858 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01357155 0,1139357 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01357155 0,11354551 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01357155 0,11315798 ! female meiosis GO:0007143 10 5 0,000 0,01357155 0,11277309 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01357155 0,11239081 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01357155 0,11201111 ! hypothalamus development GO:0021854 9 5 0,000 0,01357155 0,11163397 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01357155 0,11125936 ! cobalt ion transport GO:0006824 11 5 0,000 0,01357155 0,11088726 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01357155 0,11051763 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01357155 0,11015046 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01357155 0,10978573 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01357155 0,1094234 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01357155 0,10906345 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01357155 0,10870587 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01357155 0,10835062 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01357155 0,10799769 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01357155 0,10764704 ! transposition GO:0032196 9 5 0,000 0,01357155 0,10729867 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01357155 0,10695255 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01357155 0,10660865 ! negative chemotaxis GO:0050919 16 5 0,000 0,01357155 0,10626695 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01357155 0,10592744 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01357155 0,10559009 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01357155 0,10525489 ! behavioral response to pain GO:0048266 10 5 0,000 0,01357155 0,1049218 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01357155 0,10459082 ! Notch receptor processing GO:0007220 11 5 0,000 0,01357155 0,10426192 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01357155 0,10393508 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01357155 0,10361028 ! micturition GO:0060073 9 5 0,000 0,01357155 0,10328751 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01357155 0,10296674 ! copulation GO:0007620 9 5 0,000 0,01357155 0,10264795 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01357155 0,10233114 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01357155 0,10201628 ! bioluminescence GO:0008218 9 5 0,000 0,01357155 0,10170334 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01357155 0,10139232 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01357155 0,1010832 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01357155 0,10077596 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01357155 0,10047057 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01357155 0,10016704 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01357155 0,09986533 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01357155 0,09956543 ! grooming behavior GO:0007625 6 5 0,000 0,01357155 0,09926733 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01357155 0,09897101 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01357155 0,09867646 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01357155 0,09838365 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01357155 0,09809257 ! response to protozoan GO:0001562 13 5 0,000 0,01357155 0,09780321 ! lymph vessel development GO:0001945 10 5 0,000 0,01357155 0,09751556 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01357155 0,09722959 ! endochondral ossification GO:0001958 17 5 0,000 0,01357155 0,09694529 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01357155 0,09666265 ! single strand break repair GO:0000012 8 5 0,000 0,01357155 0,09638166 ! anagen GO:0042640 7 5 0,000 0,01357155 0,09610229 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01357155 0,09582454 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01357155 0,09554838 ! cytokine secretion GO:0050663 15 5 0,000 0,01357155 0,09527382 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01357155 0,09500083 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01357155 0,0947294 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01357155 0,09445951 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01357155 0,09419116 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01357155 0,09392433 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01357155 0,09365901 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01357155 0,09339518 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01357155 0,09313284 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01357155 0,09287196 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01357155 0,09261254 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01357155 0,09235457 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01357155 0,09209803 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01357155 0,09184291 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01357155 0,0915892 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01357155 0,09133689 ! microvillus organization GO:0032528 8 5 0,000 0,01357155 0,09108596 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01357155 0,09083641 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01357155 0,09058822 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01357155 0,09034139 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01357155 0,0900959 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01357155 0,08985173 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01357155 0,08960889 ! polyol catabolic process GO:0046174 9 5 0,000 0,01357155 0,08936736 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01357155 0,08912712 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01357155 0,08888818 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01357155 0,08865051 ! muscle cell migration GO:0014812 8 5 0,000 0,01357155 0,08841411 ! mitochondrial fission GO:0000266 8 5 0,000 0,01357155 0,08817896 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01357155 0,08794506 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01357155 0,08771241 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01357155 0,08748097 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01357155 0,08725076 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01357155 0,08702176 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01357155 0,08679395 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01357155 0,08656734 ! monocyte activation GO:0042117 10 5 0,000 0,01357155 0,0863419 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01357155 0,08611763 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01357155 0,08589453 ! response to food GO:0032094 6 5 0,000 0,01357155 0,08567258 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01357155 0,08545178 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01357155 0,08523211 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01357155 0,08501356 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01357155 0,08479614 ! forebrain neuron development GO:0021884 13 5 0,000 0,01357155 0,08457982 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01357155 0,0843646 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01357155 0,08415048 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01357155 0,08393744 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01357155 0,08372548 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01357155 0,08351458 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01357155 0,08330475 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01357155 0,08309596 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01357155 0,08288822 ! lipid glycosylation GO:0030259 7 5 0,000 0,01357155 0,08268152 ! nucleobase transport GO:0015851 6 5 0,000 0,01357155 0,08247584 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01357155 0,08227119 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01357155 0,08206755 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01357155 0,08186491 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01357155 0,08166327 ! basic amino acid transport GO:0015802 12 5 0,000 0,01357155 0,08146263 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01357155 0,08126296 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01357155 0,08106428 ! actin nucleation GO:0045010 11 5 0,000 0,01357155 0,08086656 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01357155 0,0806698 ! depurination GO:0045007 5 5 0,000 0,01357155 0,080474 ! depyrimidination GO:0045008 10 5 0,000 0,01357155 0,08027915 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01357155 0,08008524 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01357155 0,07989226 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01357155 0,07970022 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01357155 0,07950909 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01357155 0,07931887 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01357155 0,07912957 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01357155 0,07894117 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01357155 0,07875366 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01357155 0,07856704 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01357155 0,0783813 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01357155 0,07819644 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01357155 0,07801245 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01357155 0,07782932 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01357155 0,07764705 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01357155 0,07746563 ! response to arsenic GO:0046685 11 5 0,000 0,01357155 0,07728506 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01357155 0,07710532 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01357155 0,07692643 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01357155 0,07674836 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01357155 0,07657111 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01357155 0,07639468 ! response to mercury ion GO:0046689 8 5 0,000 0,01357155 0,07621906 ! response to cadmium ion GO:0046686 7 5 0,000 0,01357155 0,07604424 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01357155 0,07587023 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01357155 0,07569701 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01357155 0,07552458 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01357155 0,07535293 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01357155 0,07518206 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01357155 0,07501197 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01357155 0,07484264 ! decidualization GO:0046697 11 5 0,000 0,01357155 0,07467408 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01357155 0,07450627 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01357155 0,07433921 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01357155 0,07417291 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01357155 0,07400734 ! embryonic cleavage GO:0040016 6 5 0,000 0,01357155 0,07384252 ! peroxisome fission GO:0016559 5 5 0,000 0,01357155 0,07367842 ! histone demethylation GO:0016577 13 5 0,000 0,01357155 0,07351505 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01357155 0,07335241 ! mitotic recombination GO:0006312 9 5 0,000 0,01357155 0,07319048 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01357155 0,07302927 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01357155 0,07286877 ! metaphase plate congression GO:0051310 7 5 0,000 0,01357155 0,07270897 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01357155 0,07254987 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01357155 0,07239146 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01357155 0,07223375 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01357155 0,07207672 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01357155 0,07192037 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01357155 0,0717647 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01357155 0,0716097 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01357155 0,07145537 ! B cell homeostasis GO:0001782 13 5 0,000 0,01357155 0,0713017 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01357155 0,07114869 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01357155 0,07099634 ! metaphase GO:0051323 11 5 0,000 0,01357155 0,07084464 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01357155 0,07069358 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01357155 0,07054317 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01357155 0,0703934 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01357155 0,07024426 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01357155 0,07009575 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01357155 0,06994787 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01357155 0,06980061 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01357155 0,06965397 ! response to redox state GO:0051775 6 5 0,000 0,01357155 0,06950794 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01357155 0,06936253 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01357155 0,06921772 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01357155 0,06907352 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01357155 0,06892992 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01357155 0,06878691 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01357155 0,06864449 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01357155 0,06850266 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01357155 0,06836142 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01357155 0,06822076 ! striatum development GO:0021756 14 5 0,000 0,01357155 0,06808068 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01357155 0,06794117 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01357155 0,06780223 ! glial cell migration GO:0008347 10 5 0,000 0,01357155 0,06766386 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01357155 0,06752605 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01357155 0,0673888 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01357155 0,06725211 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01357155 0,06711597 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01357155 0,06698038 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01357155 0,06684534 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01357155 0,06671084 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01357155 0,06657689 ! neuroprotection GO:0043526 8 5 0,000 0,01357155 0,06644347 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01357155 0,06631058 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01357155 0,06617822 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01357155 0,06604639 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01357155 0,06591509 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01357155 0,0657843 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01357155 0,06565404 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01357155 0,06552429 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01357155 0,06539505 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01357155 0,06526632 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01357155 0,06513809 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01357155 0,06501037 ! spindle assembly GO:0051225 6 5 0,000 0,01357155 0,06488315 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01357155 0,06475642 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01357155 0,06463019 ! protein palmitoylation GO:0018345 12 5 0,000 0,01357155 0,06450445 ! drug metabolic process GO:0017144 7 5 0,000 0,01357155 0,0643792 ! stem cell division GO:0017145 11 5 0,000 0,01357155 0,06425444 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01357155 0,06413015 ! organ regeneration GO:0031100 7 5 0,000 0,01357155 0,06400635 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01357155 0,06388302 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01357155 0,06376017 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,01371188 0,0642958 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,0141155 0,06606163 ! regulation of lipase activity GO:0060191 137 68 1,000 0,01493806 0,06977757 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 0,01535693 0,07159728 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,01535693 0,0714609 ! negative regulation of kinase activity GO:0033673 145 70 1,000 0,01578082 0,0732938 ! cell redox homeostasis GO:0045454 114 70 1,000 0,01578082 0,07315473 ! activation of immune response GO:0002253 120 70 1,000 0,01578082 0,07301618 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,01578082 0,07287815 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,0162097 0,07471755 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0162639 0,0748262 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0162639 0,07468554 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,0162639 0,07454542 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,0162639 0,07440582 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0162639 0,07426675 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,0162639 0,07412819 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,0162639 0,07399015 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0162639 0,07385262 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,0162639 0,0737156 ! response to oxygen radical GO:0000305 11 6 0,000 0,0162639 0,07357909 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,0162639 0,07344309 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,0162639 0,07330758 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,0162639 0,07317258 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,0162639 0,07303807 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0162639 0,07290405 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,0162639 0,07277053 ! forebrain regionalization GO:0021871 9 6 0,000 0,0162639 0,07263749 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0162639 0,07250494 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0162639 0,07237288 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,0162639 0,07224129 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0162639 0,07211018 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,0162639 0,07197955 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,0162639 0,07184938 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0162639 0,07171969 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,0162639 0,07159047 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,0162639 0,07146171 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0162639 0,07133341 ! malate metabolic process GO:0006108 13 6 0,000 0,0162639 0,07120557 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,0162639 0,07107819 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,0162639 0,07095127 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,0162639 0,07082479 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,0162639 0,07069877 ! protein refolding GO:0042026 15 6 0,000 0,0162639 0,0705732 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0162639 0,07044807 ! opsonization GO:0008228 8 6 0,000 0,0162639 0,07032338 ! mating behavior GO:0007617 7 6 0,000 0,0162639 0,07019913 ! erythrocyte maturation GO:0043249 8 6 0,000 0,0162639 0,07007533 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,0162639 0,06995195 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,0162639 0,06982902 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,0162639 0,06970651 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0162639 0,06958443 ! response to interferon-gamma GO:0034341 16 6 0,000 0,0162639 0,06946278 ! toxin metabolic process GO:0009404 11 6 0,000 0,0162639 0,06934155 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0162639 0,06922075 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,0162639 0,06910036 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,0162639 0,0689804 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,0162639 0,06886085 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,0162639 0,06874171 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,0162639 0,06862299 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0162639 0,06850467 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,0162639 0,06838676 ! thymic T cell selection GO:0045061 16 6 0,000 0,0162639 0,06826926 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,0162639 0,06815216 ! protein lipoylation GO:0009249 10 6 0,000 0,0162639 0,06803546 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,0162639 0,06791916 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,0162639 0,06780326 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0162639 0,06768775 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,0162639 0,06757264 ! glutamate catabolic process GO:0006538 12 6 0,000 0,0162639 0,06745791 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,0162639 0,06734358 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0162639 0,06722963 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,0162639 0,06711606 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0162639 0,06700288 ! hyperosmotic response GO:0006972 10 6 0,000 0,0162639 0,06689008 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,0162639 0,06677766 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,0162639 0,06666562 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,0162639 0,06655395 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0162639 0,06644266 ! urea metabolic process GO:0019627 7 6 0,000 0,0162639 0,06633174 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0162639 0,06622118 ! neutrophil activation GO:0042119 7 6 0,000 0,0162639 0,066111 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0162639 0,06600118 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,0162639 0,06589172 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0162639 0,06578263 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,0162639 0,0656739 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,0162639 0,06556553 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0162639 0,06545751 ! neuron apoptosis GO:0051402 15 6 0,000 0,0162639 0,06534985 ! T cell mediated immunity GO:0002456 17 6 0,000 0,0162639 0,06524254 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0162639 0,06513559 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,0162639 0,06502898 ! carnitine transport GO:0015879 10 6 0,000 0,0162639 0,06492273 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0162639 0,06481682 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,0162639 0,06471125 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,0162639 0,06460603 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,0162639 0,06450115 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,0162639 0,06439661 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0162639 0,06429241 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,0162639 0,06418855 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,0162639 0,06408502 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,0162639 0,06398182 ! establishment of spindle localization GO:0051293 16 6 0,000 0,0162639 0,06387895 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,0162639 0,06377642 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0162639 0,06367421 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,0162639 0,06357234 ! response to UV-C GO:0010225 14 6 0,000 0,0162639 0,06347078 ! astrocyte development GO:0014002 16 6 0,000 0,0162639 0,06336955 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,0162639 0,06326865 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0162639 0,06316806 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0162639 0,06306779 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,0162639 0,06296784 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,0162639 0,06286821 ! response to copper ion GO:0046688 10 6 0,000 0,0162639 0,06276889 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,0162639 0,06266989 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,0162639 0,0625712 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0162639 0,06247281 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,0162639 0,06237474 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0162639 0,06227697 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,0162639 0,06217951 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0162639 0,06208236 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,0162639 0,06198551 ! hair follicle maturation GO:0048820 8 6 0,000 0,0162639 0,06188896 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0162639 0,06179271 ! Schwann cell development GO:0014044 15 6 0,000 0,0162639 0,06169675 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,0162639 0,0616011 ! response to pheromone GO:0019236 6 6 0,000 0,0162639 0,06150574 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,0162639 0,06141068 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,0162639 0,06131591 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,0162639 0,06122143 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,0162639 0,06112725 ! subpallium development GO:0021544 15 6 0,000 0,0162639 0,06103335 ! neural tube patterning GO:0021532 8 6 0,000 0,0162639 0,06093974 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,0162639 0,06084642 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,0162639 0,06075338 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0162639 0,06066063 ! G2 phase GO:0051319 16 6 0,000 0,0162639 0,06056815 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,0162639 0,06047597 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,0162639 0,06038406 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0162639 0,06029243 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,0162639 0,06020108 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0162639 0,06011 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,0162639 0,0600192 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0162639 0,05992867 ! receptor internalization GO:0031623 11 6 0,000 0,0162639 0,05983842 ! plasminogen activation GO:0031639 9 6 0,000 0,0162639 0,05974844 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,0162639 0,05965872 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0162639 0,05956928 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,0162639 0,0594801 ! protein deubiquitination GO:0016579 16 6 0,000 0,0162639 0,0593912 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,0162639 0,05930255 ! protein destabilization GO:0031648 9 6 0,000 0,0162639 0,05921417 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,0162639 0,05912606 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,0162639 0,0590382 ! regulation of viral transcription GO:0046782 11 6 0,000 0,0162639 0,05895061 ! progesterone metabolic process GO:0042448 12 6 0,000 0,0162639 0,05886327 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,0162639 0,0587762 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,0162639 0,05868938 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,0162639 0,05860282 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0162639 0,05851651 ! determination of adult lifespan GO:0008340 17 6 0,000 0,0162639 0,05843046 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,0162639 0,05834465 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0162639 0,05825911 ! neural plate development GO:0001840 9 6 0,000 0,0162639 0,05817381 ! catecholamine transport GO:0051937 9 6 0,000 0,0162639 0,05808876 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,0162639 0,05800396 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0162639 0,0579194 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,0162639 0,05783509 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,0162639 0,05775103 ! maternal placenta development GO:0001893 12 6 0,000 0,0162639 0,05766721 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,0162639 0,05758364 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0162639 0,0575003 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,0162639 0,05741721 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,0162639 0,05733436 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,0162639 0,05725174 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,0162639 0,05716937 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,0162639 0,05708723 GO:0055081|anion homeostasis, ! humoral immune response GO:0006959 115 73 1,000 0,01708233 0,05987392 ! acute inflammatory response GO:0002526 118 74 1,000 0,01752601 0,06134102 ! negative regulation of transferase activity GO:0051348 155 74 1,000 0,01752601 0,06125327 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01797456 0,06273122 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,01797456 0,06264173 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01888617 0,06572495 ! tRNA transcription GO:0009304 17 7 0,000 0,01894898 0,06584973 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01894898 0,0657562 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01894898 0,06566292 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01894898 0,06556992 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01894898 0,06547717 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01894898 0,06538469 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01894898 0,06529247 ! sleep GO:0030431 16 7 0,000 0,01894898 0,06520051 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01894898 0,06510881 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01894898 0,06501736 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01894898 0,06492617 ! prostate gland development GO:0030850 14 7 0,000 0,01894898 0,06483524 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01894898 0,06474456 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01894898 0,06465414 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01894898 0,06456396 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01894898 0,06447404 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01894898 0,06438437 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01894898 0,06429495 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01894898 0,06420577 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01894898 0,06411684 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01894898 0,06402816 ! glycolipid transport GO:0046836 11 7 0,000 0,01894898 0,06393973 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01894898 0,06385153 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01894898 0,06376358 ! neuron adhesion GO:0007158 14 7 0,000 0,01894898 0,06367588 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01894898 0,06358841 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01894898 0,06350118 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01894898 0,06341419 ! pericardium development GO:0060039 16 7 0,000 0,01894898 0,06332744 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01894898 0,06324093 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01894898 0,06315465 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01894898 0,06306861 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01894898 0,06298281 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01894898 0,06289723 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01894898 0,06281189 ! lipoprotein transport GO:0042953 14 7 0,000 0,01894898 0,06272678 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01894898 0,0626419 ! rhythmic behavior GO:0007622 17 7 0,000 0,01894898 0,06255725 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01894898 0,06247282 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01894898 0,06238863 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01894898 0,06230466 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01894898 0,06222092 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01894898 0,0621374 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01894898 0,0620541 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01894898 0,06197103 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01894898 0,06188818 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01894898 0,06180556 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01894898 0,06172315 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01894898 0,06164096 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01894898 0,06155899 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01894898 0,06147724 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01894898 0,06139571 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01894898 0,06131439 ! spinal cord patterning GO:0021511 14 7 0,000 0,01894898 0,06123328 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01894898 0,06115239 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01894898 0,06107172 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01894898 0,06099125 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01894898 0,060911 ! adrenal gland development GO:0030325 17 7 0,000 0,01894898 0,06083096 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01894898 0,06075113 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01894898 0,06067151 ! ovulation GO:0030728 10 7 0,000 0,01894898 0,0605921 ! adenohypophysis development GO:0021984 11 7 0,000 0,01894898 0,06051289 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01894898 0,06043389 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01894898 0,0603551 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01894898 0,06027651 ! microtubule nucleation GO:0007020 21 7 0,000 0,01894898 0,06019813 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01894898 0,06011995 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01894898 0,06004197 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01894898 0,0599642 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01894898 0,05988663 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01894898 0,05980925 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01894898 0,05973208 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01894898 0,05965511 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01894898 0,05957833 ! galactose metabolic process GO:0006012 13 7 0,000 0,01894898 0,05950175 ! vesicle fusion GO:0006906 20 7 0,000 0,01894898 0,05942537 ! response to dietary excess GO:0002021 8 7 0,000 0,01894898 0,05934918 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01894898 0,05927319 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01894898 0,05919739 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01894898 0,05912179 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01894898 0,05904638 ! organ growth GO:0035265 15 7 0,000 0,01894898 0,05897116 ! nucleoside transport GO:0015858 11 7 0,000 0,01894898 0,05889613 ! nucleoside salvage GO:0043174 11 7 0,000 0,01894898 0,0588213 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01894898 0,05874665 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01894898 0,0586722 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01894898 0,05859793 ! parturition GO:0007567 16 7 0,000 0,01894898 0,05852385 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01894898 0,05844995 ! rRNA modification GO:0000154 14 7 0,000 0,01894898 0,05837624 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01894898 0,05830272 ! spindle checkpoint GO:0031577 16 7 0,000 0,01894898 0,05822939 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01894898 0,05815623 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01894898 0,05808326 ! monocyte differentiation GO:0030224 16 7 0,000 0,01894898 0,05801048 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01894898 0,05793787 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01894898 0,05786545 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01894898 0,05779321 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01894898 0,05772115 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01894898 0,05764927 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01894898 0,05757756 ! fibrinolysis GO:0042730 11 7 0,000 0,01894898 0,05750604 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01894898 0,05743469 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01894898 0,05736352 ! eating behavior GO:0042755 8 7 0,000 0,01894898 0,05729253 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01894898 0,05722171 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01894898 0,05715106 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01894898 0,05708059 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01894898 0,0570103 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01894898 0,05694017 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01894898 0,05687022 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01894898 0,05680044 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01894898 0,05673084 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01894898 0,0566614 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01894898 0,05659213 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01894898 0,05652303 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01894898 0,0564541 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01894898 0,05638534 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01894898 0,05631674 ! histone ubiquitination GO:0016574 9 7 0,000 0,01894898 0,05624831 ! regulation of meiosis GO:0040020 12 7 0,000 0,01894898 0,05618005 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01894898 0,05611195 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01894898 0,05604402 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01894898 0,05597625 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01894898 0,05590865 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01894898 0,05584121 ! transcription termination GO:0006353 14 7 0,000 0,01894898 0,05577393 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01894898 0,05570681 ! anaphase GO:0051322 18 7 0,000 0,01894898 0,05563986 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01894898 0,05557306 ! axonal fasciculation GO:0007413 19 7 0,000 0,01894898 0,05550643 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01894898 0,05543995 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01894898 0,05537364 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01894898 0,05530748 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01894898 0,05524148 ! diuresis GO:0030146 12 7 0,000 0,01894898 0,05517564 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01894898 0,05510995 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01894898 0,05504443 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01894898 0,05497905 ! antibiotic transport GO:0042891 9 7 0,000 0,01894898 0,05491383 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01894898 0,05484877 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01894898 0,05478386 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01894898 0,0547191 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01894898 0,0546545 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01894898 0,05459005 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01894898 0,05452575 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01894898 0,0544616 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01894898 0,05439761 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01894898 0,05433376 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01894898 0,05427006 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01894898 0,05420651 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01894898 0,05414311 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01894898 0,05407986 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01894898 0,05401676 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01894898 0,0539538 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01894898 0,05389099 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01894898 0,05382833 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01894898 0,05376581 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01894898 0,05370344 ! muscle adaptation GO:0043500 13 7 0,000 0,01894898 0,05364121 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01894898 0,05357912 ! retina homeostasis GO:0001895 12 7 0,000 0,01894898 0,05351718 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01894898 0,05345538 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01894898 0,05339373 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01894898 0,05333221 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01894898 0,05327084 ! blood coagulation GO:0007596 151 79 1,000 0,01981692 0,05564683 GO:0050817|coagulation, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,02076659 0,05824658 ! protein import into nucleus GO:0006606 174 82 1,000 0,02124844 0,05952975 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02162681 0,06052038 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02162681 0,06045114 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02162681 0,06038205 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02162681 0,06031312 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02162681 0,06024435 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02162681 0,06017573 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02162681 0,06010727 ! male meiosis GO:0007140 9 8 0,000 0,02162681 0,06003897 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02162681 0,05997082 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02162681 0,05990283 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02162681 0,05983499 ! meiotic prophase I GO:0007128 14 8 0,000 0,02162681 0,0597673 ! response to zinc ion GO:0010043 12 8 0,000 0,02162681 0,05969977 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02162681 0,05963239 ! oligopeptide transport GO:0006857 16 8 0,000 0,02162681 0,05956516 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02162681 0,05949808 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02162681 0,05943115 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02162681 0,05936438 ! signal peptide processing GO:0006465 12 8 0,000 0,02162681 0,05929775 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02162681 0,05923127 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02162681 0,05916494 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02162681 0,05909876 ! succinate metabolic process GO:0006105 17 8 0,000 0,02162681 0,05903273 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02162681 0,05896685 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02162681 0,05890111 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02162681 0,05883552 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02162681 0,05877007 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02162681 0,05870477 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02162681 0,05863962 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02162681 0,05857461 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02162681 0,05850974 ! reflex GO:0060004 17 8 0,000 0,02162681 0,05844502 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02162681 0,05838044 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02162681 0,058316 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02162681 0,0582517 ! pigment granule organization GO:0048753 17 8 0,000 0,02162681 0,05818755 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02162681 0,05812354 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02162681 0,05805966 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02162681 0,05799593 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02162681 0,05793234 ! histidine catabolic process GO:0006548 10 8 0,000 0,02162681 0,05786889 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02162681 0,05780557 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02162681 0,0577424 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02162681 0,05767936 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,02162681 0,05761646 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02162681 0,0575537 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02162681 0,05749107 ! melanin metabolic process GO:0006582 17 8 0,000 0,02162681 0,05742858 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02162681 0,05736623 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02162681 0,05730401 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02162681 0,05724192 ! macrophage activation GO:0042116 13 8 0,000 0,02162681 0,05717997 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02162681 0,05711816 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02162681 0,05705647 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02162681 0,05699492 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02162681 0,05693351 ! purine salvage GO:0043101 12 8 0,000 0,02162681 0,05687222 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02162681 0,05681107 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02162681 0,05675005 ! osteoblast development GO:0002076 17 8 0,000 0,02162681 0,05668916 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02162681 0,0566284 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02162681 0,05656777 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02162681 0,05650727 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02162681 0,0564469 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02162681 0,05638665 ! response to UV-B GO:0010224 17 8 0,000 0,02162681 0,05632654 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02162681 0,05626655 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02162681 0,0562067 ! intermediate filament organization GO:0045109 12 8 0,000 0,02162681 0,05614697 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02162681 0,05608736 ! cellular extravasation GO:0045123 13 8 0,000 0,02162681 0,05602788 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02162681 0,05596853 ! response to antibiotic GO:0046677 11 8 0,000 0,02162681 0,05590931 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02162681 0,05585021 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02162681 0,05579123 ! DNA topological change GO:0006265 12 8 0,000 0,02162681 0,05573238 ! response to tropane GO:0014073 15 8 0,000 0,02162681 0,05567365 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02162681 0,05561505 ! melanosome transport GO:0032402 13 8 0,000 0,02162681 0,05555657 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02162681 0,05549821 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02162681 0,05543997 ! mast cell activation GO:0045576 14 8 0,000 0,02162681 0,05538186 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02162681 0,05532387 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02162681 0,055266 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02162681 0,05520825 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02162681 0,05515062 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02162681 0,05509311 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02162681 0,05503572 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02162681 0,05497845 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02162681 0,0549213 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02162681 0,05486427 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02162681 0,05480736 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02162681 0,05475056 ! response to tumor cell GO:0002347 16 8 0,000 0,02162681 0,05469389 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02162681 0,05463733 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02162681 0,05458088 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02162681 0,05452456 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02162681 0,05446834 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02162681 0,05441225 ! hormone catabolic process GO:0042447 17 8 0,000 0,02162681 0,05435627 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02162681 0,05430041 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02162681 0,05424466 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02162681 0,05418902 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02162681 0,0541335 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02162681 0,05407809 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02162681 0,0540228 ! adult feeding behavior GO:0008343 10 8 0,000 0,02162681 0,05396761 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02162681 0,05391255 ! ATP catabolic process GO:0006200 11 8 0,000 0,02162681 0,05385759 ! blastocyst growth GO:0001832 19 8 0,000 0,02162681 0,05380274 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02162681 0,05374801 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02162681 0,05369339 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02162681 0,05363888 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02162681 0,05358448 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02162681 0,05353019 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02162681 0,05347601 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02162681 0,05342194 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02162681 0,05336797 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02162681 0,05331412 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02162681 0,05326038 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02162681 0,05320674 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02162681 0,05315321 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02162681 0,05309979 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02162681 0,05304648 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02162681 0,05299327 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02162681 0,05294017 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02162681 0,05288718 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02162681 0,05283429 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02162681 0,05278151 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,02173493 0,05299246 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,02173493 0,05293963 ! nuclear import GO:0051170 177 83 1,000 0,02173493 0,0528869 ! response to nutrient GO:0007584 135 84 1,000 0,02222604 0,05402808 ! hemostasis GO:0007599 165 85 1,000 0,02272174 0,05517813 ! negative regulation of growth GO:0045926 168 85 1,000 0,02272174 0,05512334 ! mitochondrion organization GO:0007005 159 87 1,000 0,02372677 0,05750445 ! axon extension GO:0048675 16 9 0,000 0,0242974 0,05882909 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,0242974 0,05877084 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,0242974 0,05871271 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0242974 0,0586547 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,0242974 0,05859679 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,0242974 0,05853901 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,0242974 0,05848133 ! reproductive behavior GO:0019098 22 9 0,000 0,0242974 0,05842377 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0242974 0,05836633 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,0242974 0,05830899 ! UTP metabolic process GO:0046051 10 9 0,000 0,0242974 0,05825177 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,0242974 0,05819466 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,0242974 0,05813766 ! artery development GO:0060840 25 9 0,000 0,0242974 0,05808078 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,0242974 0,058024 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,0242974 0,05796734 ! equilibrioception GO:0050957 20 9 0,000 0,0242974 0,05791078 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,0242974 0,05785434 ! chemosensory behavior GO:0007635 21 9 0,000 0,0242974 0,05779801 ! microtubule bundle formation GO:0001578 22 9 0,000 0,0242974 0,05774178 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0242974 0,05768567 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,0242974 0,05762966 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0242974 0,05757377 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,0242974 0,05751798 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,0242974 0,0574623 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,0242974 0,05740672 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,0242974 0,05735126 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0242974 0,0572959 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0242974 0,05724065 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,0242974 0,0571855 ! protein targeting to ER GO:0045047 25 9 0,000 0,0242974 0,05713047 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,0242974 0,05707553 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,0242974 0,0570207 ! T cell selection GO:0045058 27 9 0,000 0,0242974 0,05696598 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,0242974 0,05691136 ! glycine catabolic process GO:0006546 15 9 0,000 0,0242974 0,05685685 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,0242974 0,05680244 ! endosome organization GO:0007032 20 9 0,000 0,0242974 0,05674814 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0242974 0,05669394 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,0242974 0,05663984 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0242974 0,05658585 ! mannose metabolic process GO:0006013 13 9 0,000 0,0242974 0,05653196 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,0242974 0,05647817 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,0242974 0,05642448 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,0242974 0,0563709 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,0242974 0,05631741 ! receptor clustering GO:0043113 20 9 0,000 0,0242974 0,05626403 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,0242974 0,05621075 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0242974 0,05615757 ! retinol metabolic process GO:0042572 20 9 0,000 0,0242974 0,05610449 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,0242974 0,05605151 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,0242974 0,05599864 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,0242974 0,05594586 ! oligodendrocyte development GO:0014003 11 9 0,000 0,0242974 0,05589318 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,0242974 0,0558406 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0242974 0,05578811 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,0242974 0,05573573 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0242974 0,05568345 ! response to amine stimulus GO:0014075 13 9 0,000 0,0242974 0,05563126 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0242974 0,05557917 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,0242974 0,05552718 ! erythrocyte development GO:0048821 17 9 0,000 0,0242974 0,05547528 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0242974 0,05542349 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,0242974 0,05537178 ! renal water homeostasis GO:0003091 15 9 0,000 0,0242974 0,05532018 ! postreplication repair GO:0006301 25 9 0,000 0,0242974 0,05526867 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,0242974 0,05521726 ! icosanoid secretion GO:0032309 15 9 0,000 0,0242974 0,05516594 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0242974 0,05511472 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,0242974 0,05506359 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,0242974 0,05501256 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,0242974 0,05496162 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0242974 0,05491078 ! sterol catabolic process GO:0016127 14 9 0,000 0,0242974 0,05486003 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0242974 0,05480938 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,0242974 0,05475881 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,0242974 0,05470834 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,0242974 0,05465797 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,0242974 0,05460768 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,0242974 0,05455749 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,0242974 0,0545074 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,0242974 0,05445739 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,0242974 0,05440747 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,0242974 0,05435765 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0242974 0,05430792 ! purine base metabolic process GO:0006144 25 9 0,000 0,0242974 0,05425828 ! pigment granule transport GO:0051904 17 9 0,000 0,0242974 0,05420872 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,0242974 0,05415926 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,0242974 0,05410989 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,0242974 0,05406061 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0242974 0,05401142 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,0242974 0,05396232 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,0242974 0,05391331 ! regulation of DNA binding GO:0051101 167 89 1,000 0,0247498 0,0548673 ! protein localization in nucleus GO:0034504 192 89 1,000 0,0247498 0,05481756 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,025268 0,05591461 ! ossification GO:0001503 205 91 1,000 0,02579062 0,05701944 ! gland development GO:0048732 220 91 1,000 0,02579062 0,05696789 ! bone development GO:0060348 206 92 1,000 0,02631763 0,05807947 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,02631763 0,05802705 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,026849 0,05914528 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02696078 0,05933801 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,02696078 0,0592846 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02696078 0,05923128 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02696078 0,05917807 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02696078 0,05912494 ! associative learning GO:0008306 21 10 0,000 0,02696078 0,05907192 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,02696078 0,05901898 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02696078 0,05896615 ! phosphate transport GO:0006817 24 10 0,000 0,02696078 0,0589134 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02696078 0,05886076 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02696078 0,0588082 ! CTP metabolic process GO:0046036 11 10 0,000 0,02696078 0,05875574 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02696078 0,05870338 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02696078 0,0586511 ! GTP metabolic process GO:0046039 11 10 0,000 0,02696078 0,05859892 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02696078 0,05854683 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02696078 0,05849484 ! social behavior GO:0035176 29 10 0,000 0,02696078 0,05844293 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02696078 0,05839112 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02696078 0,0583394 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02696078 0,05828778 ! androgen metabolic process GO:0008209 17 10 0,000 0,02696078 0,05823624 ! phospholipid efflux GO:0033700 19 10 0,000 0,02696078 0,05818479 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02696078 0,05813344 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02696078 0,05808218 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02696078 0,058031 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02696078 0,05797992 ! pathogenesis GO:0009405 17 10 0,000 0,02696078 0,05792892 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02696078 0,05787802 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02696078 0,05782721 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02696078 0,05777648 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02696078 0,05772584 ! endoderm development GO:0007492 18 10 0,000 0,02696078 0,05767529 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02696078 0,05762484 ! arginine catabolic process GO:0006527 17 10 0,000 0,02696078 0,05757446 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02696078 0,05752418 ! proline metabolic process GO:0006560 13 10 0,000 0,02696078 0,05747398 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02696078 0,05742388 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02696078 0,05737386 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02696078 0,05732392 ! V(D)J recombination GO:0033151 34 10 0,000 0,02696078 0,05727408 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02696078 0,05722432 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02696078 0,05717464 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02696078 0,05712505 ! B cell proliferation GO:0042100 19 10 0,000 0,02696078 0,05707555 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02696078 0,05702614 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02696078 0,05697681 ! multicellular organism growth GO:0035264 19 10 0,000 0,02696078 0,05692756 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02696078 0,0568784 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02696078 0,05682932 ! ruffle organization GO:0031529 17 10 0,000 0,02696078 0,05678033 ! epithelial cell development GO:0002064 21 10 0,000 0,02696078 0,05673143 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02696078 0,0566826 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02696078 0,05663387 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02696078 0,05658521 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02696078 0,05653664 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02696078 0,05648815 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02696078 0,05643975 ! motor axon guidance GO:0008045 22 10 0,000 0,02696078 0,05639143 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02696078 0,05634319 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02696078 0,05629503 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02696078 0,05624696 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02696078 0,05619896 ! segment specification GO:0007379 15 10 0,000 0,02696078 0,05615105 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02696078 0,05610323 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02696078 0,05605548 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02696078 0,05600781 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02696078 0,05596023 ! response to dsRNA GO:0043331 23 10 0,000 0,02696078 0,05591272 ! DNA ligation GO:0006266 18 10 0,000 0,02696078 0,0558653 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02696078 0,05581795 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02696078 0,05577069 ! melanosome localization GO:0032400 16 10 0,000 0,02696078 0,05572351 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02696078 0,0556764 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02696078 0,05562938 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02696078 0,05558244 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02696078 0,05553557 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02696078 0,05548878 ! induction of an organ GO:0001759 17 10 0,000 0,02696078 0,05544208 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02696078 0,05539545 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02696078 0,0553489 ! protein sumoylation GO:0016925 17 10 0,000 0,02696078 0,05530242 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02696078 0,05525603 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02696078 0,05520971 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02696078 0,05516347 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02696078 0,05511731 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02696078 0,05507123 ! salivary gland development GO:0007431 28 10 0,000 0,02696078 0,05502522 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02696078 0,05497929 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02696078 0,05493343 ! midbrain development GO:0030901 14 10 0,000 0,02696078 0,05488766 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02696078 0,05484195 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02696078 0,05479633 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02696078 0,05475078 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02696078 0,0547053 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02696078 0,05465991 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02696078 0,05461458 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02696078 0,05456933 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02696078 0,05452416 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02696078 0,05447906 ! detection of calcium ion GO:0005513 24 10 0,000 0,02696078 0,05443404 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02696078 0,05438909 ! blastocyst formation GO:0001825 18 10 0,000 0,02696078 0,05434421 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02696078 0,05429941 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02696078 0,05425468 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02696078 0,05421003 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02696078 0,05416545 ! response to nicotine GO:0035094 20 10 0,000 0,02696078 0,05412094 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02696078 0,05407651 ! regulation of defense response GO:0031347 171 95 1,000 0,02792473 0,055964 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,02792473 0,05591813 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,02901759 0,05805895 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02961696 0,05920969 ! respiratory burst GO:0045730 17 11 0,000 0,02961696 0,05916128 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02961696 0,05911294 ! neuron fate specification GO:0048665 18 11 0,000 0,02961696 0,05906469 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02961696 0,05901651 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02961696 0,05896841 ! thyroid gland development GO:0030878 26 11 0,000 0,02961696 0,05892039 ! synapsis GO:0007129 14 11 0,000 0,02961696 0,05887245 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02961696 0,05882459 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02961696 0,0587768 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02961696 0,05872909 ! response to pain GO:0048265 27 11 0,000 0,02961696 0,05868146 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02961696 0,05863391 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02961696 0,05858643 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,02961696 0,05853903 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02961696 0,05849171 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02961696 0,05844446 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02961696 0,05839729 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02961696 0,05835019 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02961696 0,05830318 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02961696 0,05825623 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02961696 0,05820937 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02961696 0,05816257 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02961696 0,05811586 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02961696 0,05806921 ! UV protection GO:0009650 20 11 0,000 0,02961696 0,05802265 ! adult heart development GO:0007512 16 11 0,000 0,02961696 0,05797616 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02961696 0,05792974 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02961696 0,05788339 ! macroautophagy GO:0016236 19 11 0,000 0,02961696 0,05783712 ! temperature homeostasis GO:0001659 18 11 0,000 0,02961696 0,05779093 ! behavioral fear response GO:0001662 27 11 0,000 0,02961696 0,05774481 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02961696 0,05769876 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02961696 0,05765278 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02961696 0,05760688 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02961696 0,05756105 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02961696 0,0575153 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02961696 0,05746961 ! regulation of organ growth GO:0046620 14 11 0,000 0,02961696 0,057424 ! pigment granule localization GO:0051875 20 11 0,000 0,02961696 0,05737846 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02961696 0,057333 ! vasoconstriction GO:0042310 20 11 0,000 0,02961696 0,0572876 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02961696 0,05724228 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02961696 0,05719703 ! embryonic axis specification GO:0000578 19 11 0,000 0,02961696 0,05715185 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02961696 0,05710674 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02961696 0,0570617 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02961696 0,05701674 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02961696 0,05697184 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02961696 0,05692702 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02961696 0,05688227 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02961696 0,05683758 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02961696 0,05679297 ! prophase GO:0051324 17 11 0,000 0,02961696 0,05674842 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02961696 0,05670395 ! nucleosome positioning GO:0016584 15 11 0,000 0,02961696 0,05665955 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02961696 0,05661521 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02961696 0,05657095 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02961696 0,05652675 ! apical protein localization GO:0045176 18 11 0,000 0,02961696 0,05648262 ! acid secretion GO:0046717 20 11 0,000 0,02961696 0,05643857 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02961696 0,05639458 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02961696 0,05635066 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02961696 0,0563068 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02961696 0,05626302 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02961696 0,0562193 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,02961696 0,05617565 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02961696 0,05613207 ! oocyte development GO:0048599 20 11 0,000 0,02961696 0,05608856 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02961696 0,05604511 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02961696 0,05600174 ! embryonic gut development GO:0048566 19 11 0,000 0,02961696 0,05595842 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02961696 0,05591518 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02961696 0,055872 ! activation of innate immune response GO:0002218 16 11 0,000 0,02961696 0,05582889 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02961696 0,05578585 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02961696 0,05574287 ! lysogeny GO:0030069 22 11 0,000 0,02961696 0,05569996 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02961696 0,05565711 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02961696 0,05561433 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02961696 0,05557161 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,03068853 0,05753804 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 1,000 0,03068853 0,05749392 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,03226597 0,06040289 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,03226597 0,06035663 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,03226597 0,06031046 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,03226597 0,06026435 ! mating GO:0007618 17 12 0,000 0,03226597 0,06021831 ! protein complex disassembly GO:0043241 28 12 0,000 0,03226597 0,06017234 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03226597 0,06012644 ! hippocampus development GO:0021766 29 12 0,000 0,03226597 0,06008061 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,03226597 0,06003486 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,03226597 0,05998917 ! T cell proliferation GO:0042098 32 12 0,000 0,03226597 0,05994355 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03226597 0,059898 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,03226597 0,05985252 ! ventral spinal cord development GO:0021517 25 12 0,000 0,03226597 0,05980711 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,03226597 0,05976176 ! drug transport GO:0015893 16 12 0,000 0,03226597 0,05971649 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,03226597 0,05967128 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,03226597 0,05962615 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,03226597 0,05958108 ! polyamine metabolic process GO:0006595 18 12 0,000 0,03226597 0,05953608 ! focal adhesion formation GO:0048041 37 12 0,000 0,03226597 0,05949114 ! mitotic spindle organization GO:0007052 23 12 0,000 0,03226597 0,05944628 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,03226597 0,05940148 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,03226597 0,05935675 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,03226597 0,05931209 ! lipid digestion GO:0044241 21 12 0,000 0,03226597 0,05926749 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,03226597 0,05922296 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03226597 0,0591785 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,03226597 0,05913411 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,03226597 0,05908978 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03226597 0,05904552 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,03226597 0,05900132 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,03226597 0,05895719 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,03226597 0,05891313 ! snRNA metabolic process GO:0016073 30 12 0,000 0,03226597 0,05886913 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,03226597 0,0588252 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,03226597 0,05878133 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03226597 0,05873753 ! cranial nerve development GO:0021545 23 12 0,000 0,03226597 0,05869379 ! fucose catabolic process GO:0019317 25 12 0,000 0,03226597 0,05865012 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,03226597 0,05860652 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,03226597 0,05856298 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03226597 0,0585195 ! zymogen activation GO:0031638 18 12 0,000 0,03226597 0,05847609 ! T cell homeostasis GO:0043029 28 12 0,000 0,03226597 0,05843274 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,03226597 0,05838946 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,03226597 0,05834624 ! oocyte differentiation GO:0009994 21 12 0,000 0,03226597 0,05830308 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,03226597 0,05825999 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,03226597 0,05821696 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,03226597 0,058174 GO:0042130|negative regulation of T cell proliferation, ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,03226597 0,0581311 ! defense response to fungus GO:0050832 15 12 0,000 0,03226597 0,05808826 ! developmental induction GO:0031128 22 12 0,000 0,03226597 0,05804548 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 0,000 0,03226597 0,05800277 ! response to cold GO:0009409 17 12 0,000 0,03226597 0,05796012 ! establishment of cell polarity GO:0030010 21 12 0,000 0,03226597 0,05791753 ! regulation of synapse organization GO:0050807 18 12 0,000 0,03226597 0,05787501 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03490782 0,06256772 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03490782 0,06252185 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03490782 0,06247605 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03490782 0,06243031 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03490782 0,06238464 ! peroxisomal transport GO:0043574 28 13 0,000 0,03490782 0,06233904 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03490782 0,0622935 ! cartilage condensation GO:0001502 22 13 0,000 0,03490782 0,06224803 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,03490782 0,06220263 ! organelle fusion GO:0048284 36 13 0,000 0,03490782 0,06215729 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03490782 0,06211202 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,03490782 0,06206681 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,03490782 0,06202168 ! endocrine pancreas development GO:0031018 25 13 0,000 0,03490782 0,0619766 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03490782 0,06193159 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03490782 0,06188665 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03490782 0,06184177 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03490782 0,06179696 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03490782 0,06175221 ! methionine metabolic process GO:0006555 31 13 0,000 0,03490782 0,06170753 ! plasma membrane organization GO:0007009 27 13 0,000 0,03490782 0,06166291 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03490782 0,06161836 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03490782 0,06157387 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03490782 0,06152944 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,03490782 0,06148508 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,03490782 0,06144078 ! cytokine metabolic process GO:0042107 24 13 0,000 0,03490782 0,06139655 ! exocrine system development GO:0035272 34 13 0,000 0,03490782 0,06135238 ! asymmetric protein localization GO:0008105 24 13 0,000 0,03490782 0,06130827 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,03490782 0,06126423 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,03490782 0,06122025 ! L-glutamate transport GO:0015813 30 13 0,000 0,03490782 0,06117633 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03490782 0,06113248 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03490782 0,06108868 ! protein homotetramerization GO:0051289 24 13 0,000 0,03490782 0,06104496 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03490782 0,06100129 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03490782 0,06095769 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,03490782 0,06091415 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,03490782 0,06087067 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03490782 0,06082725 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03490782 0,06078389 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03490782 0,0607406 ! histone methylation GO:0016571 29 13 0,000 0,03490782 0,06069737 ! chromatin silencing GO:0006342 29 13 0,000 0,03490782 0,0606542 ! gland morphogenesis GO:0022612 31 13 0,000 0,03490782 0,06061109 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,03490782 0,06056804 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03490782 0,06052506 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,03490782 0,06048213 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,03490782 0,06043927 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,03490782 0,06039646 ! spleen development GO:0048536 24 13 0,000 0,03490782 0,06035372 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03490782 0,06031104 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,03490782 0,06026841 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03490782 0,06022585 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,03490782 0,06018335 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03490782 0,06014091 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03490782 0,06009852 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03490782 0,0600562 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03490782 0,06001394 ! insulin secretion GO:0030073 24 13 0,000 0,03490782 0,05997173 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03490782 0,05992959 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,03490782 0,0598875 ! acrosome reaction GO:0007340 19 13 0,000 0,03490782 0,05984548 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03490782 0,05980351 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03490782 0,0597616 ! rRNA transcription GO:0009303 28 14 0,000 0,03754253 0,06422717 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03754253 0,06418223 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03754253 0,06413735 ! water transport GO:0006833 21 14 0,000 0,03754253 0,06409253 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,03754253 0,06404777 ! non-recombinational repair GO:0000726 29 14 0,000 0,03754253 0,06400307 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,03754253 0,06395844 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03754253 0,06391387 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03754253 0,06386936 ! lipid localization GO:0010876 32 14 0,000 0,03754253 0,06382492 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,03754253 0,06378053 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03754253 0,06373621 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03754253 0,06369195 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03754253 0,06364775 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03754253 0,06360361 ! arginine metabolic process GO:0006525 21 14 0,000 0,03754253 0,06355953 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03754253 0,06351552 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03754253 0,06347156 ! regulation of heart rate GO:0002027 25 14 0,000 0,03754253 0,06342767 ! fear response GO:0042596 34 14 0,000 0,03754253 0,06338383 ! organic alcohol transport GO:0015850 29 14 0,000 0,03754253 0,06334006 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03754253 0,06329635 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03754253 0,06325269 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03754253 0,0632091 ! bone mineralization GO:0030282 18 14 0,000 0,03754253 0,06316557 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03754253 0,0631221 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03754253 0,06307868 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03754253 0,06303533 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03754253 0,06299204 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03754253 0,0629488 ! regulation of cellular pH GO:0030641 27 14 0,000 0,03754253 0,06290563 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03754253 0,06286251 ! ribosome assembly GO:0042255 18 14 0,000 0,03754253 0,06281946 ! cerebellum development GO:0021549 23 14 0,000 0,03754253 0,06277646 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03754253 0,06273352 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03754253 0,06269064 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03754253 0,06264782 ! response to gamma radiation GO:0010332 30 14 0,000 0,03754253 0,06260505 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03754253 0,06256235 ! NADP metabolic process GO:0006739 24 14 0,000 0,03754253 0,0625197 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03754253 0,06247711 ! oxygen transport GO:0015671 22 14 0,000 0,03754253 0,06243458 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03754253 0,06239211 ! male genitalia development GO:0030539 26 14 0,000 0,03754253 0,0623497 ! regulation of axon extension GO:0030516 43 14 0,000 0,03754253 0,06230734 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03754253 0,06226504 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,03754253 0,0622228 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04017012 0,06653262 ! lactation GO:0007595 30 15 0,000 0,04017012 0,06648754 ! reproductive cellular process GO:0048610 22 15 0,000 0,04017012 0,06644253 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04017012 0,06639757 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,04017012 0,06635268 ! superoxide anion generation GO:0042554 22 15 0,000 0,04017012 0,06630785 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,04017012 0,06626307 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,04017012 0,06621836 ! copper ion transport GO:0006825 22 15 0,000 0,04017012 0,06617371 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,04017012 0,06612912 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,04017012 0,06608459 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,04017012 0,06604012 ! sulfate transport GO:0008272 27 15 0,000 0,04017012 0,06599571 ! response to cAMP GO:0051591 25 15 0,000 0,04017012 0,06595135 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,04017012 0,06590706 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,04017012 0,06586283 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,04017012 0,06581865 ! response to hexose stimulus GO:0009746 25 15 0,000 0,04017012 0,06577454 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,04017012 0,06573048 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,04017012 0,06568649 ! vesicle coating GO:0006901 38 15 0,000 0,04017012 0,06564255 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,04017012 0,06559867 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,04017012 0,06555485 ! regulation of exocytosis GO:0017157 26 15 0,000 0,04017012 0,06551109 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,04017012 0,06546739 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,04017012 0,06542374 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,04017012 0,06538016 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,04017012 0,06533663 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,04017012 0,06529316 ! regulation of vasodilation GO:0042312 27 15 0,000 0,04017012 0,06524974 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,04017012 0,06520639 ! histone deacetylation GO:0016575 24 15 0,000 0,04017012 0,06516309 ! water homeostasis GO:0030104 28 15 0,000 0,04017012 0,06511985 ! cofactor transport GO:0051181 30 15 0,000 0,04017012 0,06507667 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04017012 0,06503354 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,04017012 0,06499047 ! intestinal absorption GO:0050892 31 15 0,000 0,04017012 0,06494746 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04017012 0,06490451 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,04017012 0,06486161 ! heme biosynthetic process GO:0006783 33 15 0,000 0,04017012 0,06481877 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,04017012 0,06477598 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,04017012 0,06473325 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,04017012 0,06469058 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,04017012 0,06464797 ! actin filament polymerization GO:0030041 27 15 0,000 0,04017012 0,06460541 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,04017012 0,0645629 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,04279062 0,06872944 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,04279062 0,06868428 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,04279062 0,06863918 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,04279062 0,06859415 ! bone remodeling GO:0046849 28 16 0,000 0,04279062 0,06854917 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,04279062 0,06850425 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,04279062 0,06845938 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04279062 0,06841458 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,04279062 0,06836984 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,04279062 0,06832515 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,04279062 0,06828052 ! startle response GO:0001964 28 16 0,000 0,04279062 0,06823595 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,04279062 0,06819144 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,04279062 0,06814699 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,04279062 0,06810259 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,04279062 0,06805825 ! protein polyubiquitination GO:0000209 41 16 0,000 0,04279062 0,06801397 ! glutamate metabolic process GO:0006536 25 16 0,000 0,04279062 0,06796975 ! pituitary gland development GO:0021983 30 16 0,000 0,04279062 0,06792559 ! response to osmotic stress GO:0006970 27 16 0,000 0,04279062 0,06788148 ! lysosomal transport GO:0007041 31 16 0,000 0,04279062 0,06783743 ! fructose metabolic process GO:0006000 25 16 0,000 0,04279062 0,06779344 ! L-amino acid transport GO:0015807 33 16 0,000 0,04279062 0,0677495 ! stem cell development GO:0048864 46 16 0,000 0,04279062 0,06770562 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04279062 0,0676618 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04279062 0,06761803 ! intermediate filament-based process GO:0045103 36 16 0,000 0,04279062 0,06757432 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,04279062 0,06753067 ! negative regulation of immune response GO:0050777 38 16 0,000 0,04279062 0,06748707 ! axon cargo transport GO:0008088 46 16 0,000 0,04279062 0,06744353 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,04279062 0,06740005 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,04279062 0,06735662 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,04279062 0,06731325 ! DNA replication initiation GO:0006270 28 16 0,000 0,04279062 0,06726993 ! neuron recognition GO:0008038 40 16 0,000 0,04279062 0,06722667 ! mRNA splice site selection GO:0006376 44 16 0,000 0,04279062 0,06718347 ! tissue regeneration GO:0042246 27 16 0,000 0,04279062 0,06714032 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,04279062 0,06709723 ! biomineral formation GO:0031214 22 16 0,000 0,04279062 0,06705419 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,04279062 0,0670112 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,04279062 0,06696828 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,04279062 0,0669254 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04279062 0,06688258 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,04279062 0,06683982 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,04279062 0,06679711 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,04279062 0,06675446 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,04279062 0,06671186 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04279062 0,06666931 ! peptide hormone processing GO:0016486 27 16 0,000 0,04279062 0,06662682 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,04540403 0,07065098 ! metencephalon development GO:0022037 32 17 0,000 0,04540403 0,07060601 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,04540403 0,0705611 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,04540403 0,07051624 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,04540403 0,07047144 ! signal complex assembly GO:0007172 47 17 0,000 0,04540403 0,07042669 ! endothelial cell migration GO:0043542 31 17 0,000 0,04540403 0,07038201 ! gene silencing by RNA GO:0031047 38 17 0,000 0,04540403 0,07033738 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,04540403 0,0702928 ! glial cell development GO:0021782 28 17 0,000 0,04540403 0,07024829 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,04540403 0,07020383 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,04540403 0,07015942 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,04540403 0,07011507 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,04540403 0,07007078 ! myoblast differentiation GO:0045445 50 17 0,000 0,04540403 0,07002654 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,04540403 0,06998236 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,04540403 0,06993824 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,04540403 0,06989417 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,04540403 0,06985015 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,04540403 0,0698062 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,04540403 0,06976229 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,04540403 0,06971844 ! membrane budding GO:0006900 42 17 0,000 0,04540403 0,06967465 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,04540403 0,06963091 ! regulation of protein binding GO:0043393 33 17 0,000 0,04540403 0,06958723 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,04540403 0,0695436 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,04540403 0,06950003 ! genitalia development GO:0048806 32 17 0,000 0,04540403 0,06945651 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,04540403 0,06941304 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,04540403 0,06936963 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,04540403 0,06932628 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,04540403 0,06928298 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,04540403 0,06923973 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,04540403 0,06919653 ! steroid catabolic process GO:0006706 34 17 0,000 0,04540403 0,06915339 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,04540403 0,06911031 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,04540403 0,06906728 ! gas transport GO:0015669 26 17 0,000 0,04540403 0,0690243 ! organic cation transport GO:0015695 32 17 0,000 0,04540403 0,06898137 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,04540403 0,0689385 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,04540403 0,06889568 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,04801038 0,07280531 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,04801038 0,07276015 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04801038 0,07271504 ! limbic system development GO:0021761 40 18 0,000 0,04801038 0,07266999 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04801038 0,07262499 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04801038 0,07258005 ! adult walking behavior GO:0007628 36 18 0,000 0,04801038 0,07253516 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04801038 0,07249033 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04801038 0,07244556 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04801038 0,07240084 ! centrosome cycle GO:0007098 26 18 0,000 0,04801038 0,07235617 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04801038 0,07231156 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,04801038 0,07226701 ! glycine metabolic process GO:0006544 30 18 0,000 0,04801038 0,07222251 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04801038 0,07217807 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,04801038 0,07213368 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,04801038 0,07208934 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,04801038 0,07204506 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,04801038 0,07200083 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,04801038 0,07195666 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04801038 0,07191254 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04801038 0,07186848 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04801038 0,07182447 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,04801038 0,07178051 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04801038 0,07173661 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,04801038 0,07169276 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,04801038 0,07164897 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04801038 0,07160522 ! detection of bacterium GO:0016045 22 18 0,000 0,04801038 0,07156154 ! nerve development GO:0021675 34 18 0,000 0,04801038 0,0715179 ! defense response to virus GO:0051607 43 18 0,000 0,04801038 0,07147432 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04801038 0,07143079 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,04801038 0,07138731 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,05060969 0,07520649 ! positive regulation of translation GO:0045727 31 19 0,000 0,05060969 0,07516077 ! neuron maturation GO:0042551 46 19 0,000 0,05060969 0,07511511 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,05060969 0,0750695 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,05060969 0,07502395 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,05060969 0,07497845 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,05060969 0,07493301 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,05060969 0,07488762 ! inositol metabolic process GO:0006020 33 19 0,000 0,05060969 0,07484229 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05060969 0,07479702 ! memory GO:0007613 34 19 0,000 0,05060969 0,07475179 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,05060969 0,07470663 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,05060969 0,07466151 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,05060969 0,07461646 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,05060969 0,07457145 ! cerebral cortex development GO:0021987 40 19 0,000 0,05060969 0,0745265 ! pigmentation during development GO:0048066 42 19 0,000 0,05060969 0,07448161 ! heme metabolic process GO:0042168 40 19 0,000 0,05060969 0,07443676 ! neuromuscular junction development GO:0007528 43 19 0,000 0,05060969 0,07439198 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,05060969 0,07434724 ! response to fungus GO:0009620 26 19 0,000 0,05060969 0,07430256 ! peptide cross-linking GO:0018149 39 19 0,000 0,05060969 0,07425794 ! protein export from nucleus GO:0006611 40 19 0,000 0,05060969 0,07421337 ! heart process GO:0003015 32 19 0,000 0,05060969 0,07416885 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,05060969 0,07412438 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,05060969 0,07407997 ! visual learning GO:0008542 38 19 0,000 0,05060969 0,07403561 ! cellular pigmentation GO:0033059 37 19 0,000 0,05060969 0,0739913 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,05060969 0,07394705 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,05060969 0,07390285 ! vitamin transport GO:0051180 31 19 0,000 0,05060969 0,0738587 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,05060969 0,07381461 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,05060969 0,07377056 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,05060969 0,07372657 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,05060969 0,07368264 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,05060969 0,07363875 ! cilium assembly GO:0042384 38 19 0,000 0,05060969 0,07359492 ! peptide hormone secretion GO:0030072 32 19 0,000 0,05060969 0,07355114 ! protein secretion GO:0009306 45 20 0,000 0,05320197 0,07727254 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,05320197 0,07722663 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,05320197 0,07718077 ! positive regulation of ossification GO:0045778 50 20 0,000 0,05320197 0,07713496 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,05320197 0,07708921 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,05320197 0,07704352 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,05320197 0,07699788 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,05320197 0,07695229 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,05320197 0,07690675 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,05320197 0,07686127 ! bile acid metabolic process GO:0008206 34 20 0,000 0,05320197 0,07681585 ! response to alkaloid GO:0043279 38 20 0,000 0,05320197 0,07677047 ! retinoid metabolic process GO:0001523 34 20 0,000 0,05320197 0,07672516 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,05320197 0,07667989 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,05320197 0,07663468 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,05320197 0,07658952 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,05320197 0,07654441 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,05320197 0,07649936 ! actin filament bundle formation GO:0051017 47 20 0,000 0,05320197 0,07645436 ! body fluid secretion GO:0007589 33 20 0,000 0,05320197 0,07640941 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,05320197 0,07636452 ! peptide secretion GO:0002790 38 20 0,000 0,05320197 0,07631968 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,05320197 0,07627489 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,05320197 0,07623015 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,05320197 0,07618547 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,05320197 0,07614084 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,05320197 0,07609626 ! cell-cell junction organization GO:0045216 43 20 0,000 0,05320197 0,07605173 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,05320197 0,07600726 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,05320197 0,07596284 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,05320197 0,07591847 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,05320197 0,07587415 ! regulation of glucose import GO:0046324 30 20 0,000 0,05320197 0,07582988 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,05320197 0,07578566 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,05320197 0,0757415 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,05320197 0,07569739 ! negative regulation of translation GO:0017148 32 20 0,000 0,05320197 0,07565333 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,05320197 0,07560932 ! regulation of cell killing GO:0031341 46 21 0,000 0,05578725 0,07923735 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,05578725 0,07919131 ! hormone secretion GO:0046879 39 21 0,000 0,05578725 0,07914532 ! cAMP metabolic process GO:0046058 41 21 0,000 0,05578725 0,07909939 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,05578725 0,07905351 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,05578725 0,07900768 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,05578725 0,0789619 ! ovarian follicle development GO:0001541 39 21 0,000 0,05578725 0,07891618 ! smooth muscle contraction GO:0006939 48 21 0,000 0,05578725 0,07887051 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,05578725 0,0788249 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,05578725 0,07877933 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,05578725 0,07873382 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,05578725 0,07868836 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,05578725 0,07864296 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,05578725 0,07859761 ! sensory perception of pain GO:0019233 33 21 0,000 0,05578725 0,0785523 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,05578725 0,07850706 ! diencephalon development GO:0021536 36 21 0,000 0,05578725 0,07846186 ! collagen fibril organization GO:0030199 62 21 0,000 0,05578725 0,07841671 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,05578725 0,07837162 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,05578725 0,07832658 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,05578725 0,07828159 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,05578725 0,07823665 ! collagen catabolic process GO:0030574 29 21 0,000 0,05578725 0,07819177 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,05578725 0,07814693 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,05578725 0,07810215 ! sperm-egg recognition GO:0035036 23 21 0,000 0,05578725 0,07805742 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,05578725 0,07801273 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,05836554 0,08157152 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,05836554 0,08152488 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,05836554 0,08147829 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,05836554 0,08143176 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,05836554 0,08138528 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,05836554 0,08133886 ! microtubule-based transport GO:0010970 59 22 0,000 0,05836554 0,08129248 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,05836554 0,08124616 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,05836554 0,08119989 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,05836554 0,08115368 ! vacuolar transport GO:0007034 41 22 0,000 0,05836554 0,08110752 ! central nervous system neuron development GO:0021954 47 22 0,000 0,05836554 0,08106141 ! fucose metabolic process GO:0006004 44 22 0,000 0,05836554 0,08101535 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,05836554 0,08096934 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,05836554 0,08092339 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,05836554 0,08087749 ! ureteric bud development GO:0001657 50 22 0,000 0,05836554 0,08083164 ! cell aging GO:0007569 48 22 0,000 0,05836554 0,08078584 ! stem cell differentiation GO:0048863 57 22 0,000 0,05836554 0,0807401 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,05836554 0,0806944 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,05836554 0,08064876 ! renal system process GO:0003014 42 22 0,000 0,05836554 0,08060317 ! vasodilation GO:0042311 40 22 0,000 0,05836554 0,08055763 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,05836554 0,08051215 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,05836554 0,08046671 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,05836554 0,08042133 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,05836554 0,08037599 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,05836554 0,08033071 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,05836554 0,08028548 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,05836554 0,0802403 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,05836554 0,08019517 ! sarcomere organization GO:0045214 32 22 0,000 0,05836554 0,08015009 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,05836554 0,08010506 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,05836554 0,08006009 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,05836554 0,08001516 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,05836554 0,07997028 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,05836554 0,07992546 ! gut development GO:0048565 44 22 0,000 0,05836554 0,07988068 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,05836554 0,07983595 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,05836554 0,07979128 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,05836554 0,07974665 ! protein stabilization GO:0050821 41 22 0,000 0,05836554 0,07970208 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,06093686 0,0831669 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,06093686 0,08312047 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,06093686 0,08307408 ! gluconeogenesis GO:0006094 38 23 0,000 0,06093686 0,08302775 ! glycerol metabolic process GO:0006071 40 23 0,000 0,06093686 0,08298147 ! viral genome replication GO:0019079 44 23 0,000 0,06093686 0,08293524 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,06093686 0,08288906 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,06093686 0,08284294 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,06093686 0,08279686 ! regeneration GO:0031099 42 23 0,000 0,06093686 0,08275084 ! axis specification GO:0009798 43 23 0,000 0,06093686 0,08270486 ! visual behavior GO:0007632 46 23 0,000 0,06093686 0,08265894 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,06093686 0,08261307 ! response to ethanol GO:0045471 47 23 0,000 0,06093686 0,08256725 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,06093686 0,08252148 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,06093686 0,08247576 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,06093686 0,0824301 ! peroxisome organization GO:0007031 43 23 0,000 0,06093686 0,08238448 ! lysosome organization GO:0007040 47 23 0,000 0,06093686 0,08233891 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,06093686 0,0822934 ! vesicle targeting GO:0006903 49 23 0,000 0,06093686 0,08224793 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,06093686 0,08220252 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,06093686 0,08215715 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,06093686 0,08211183 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,06093686 0,08206657 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,06093686 0,08202135 ! DNA modification GO:0006304 36 23 0,000 0,06093686 0,08197619 ! fatty acid transport GO:0015908 47 23 0,000 0,06093686 0,08193107 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,06093686 0,081886 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,06093686 0,08184099 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,06093686 0,08179602 ! hormone transport GO:0009914 41 23 0,000 0,06093686 0,0817511 ! cell-cell recognition GO:0009988 28 23 0,000 0,06093686 0,08170623 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,06093686 0,08166141 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,06093686 0,08161664 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,06093686 0,08157192 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,06350124 0,08495812 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,06350124 0,08491162 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,06350124 0,08486516 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,06350124 0,08481876 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,06350124 0,08477242 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,06350124 0,08472612 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,06350124 0,08467987 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,06350124 0,08463367 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,06350124 0,08458753 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,06350124 0,08454143 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,06350124 0,08449538 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,06350124 0,08444939 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,06350124 0,08440344 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,06350124 0,08435754 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,06350124 0,0843117 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,06350124 0,0842659 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,06350124 0,08422015 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,06350124 0,08417446 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,06350124 0,08412881 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,06350124 0,08408321 ! membrane depolarization GO:0051899 45 24 0,000 0,06350124 0,08403766 ! pallium development GO:0021543 56 24 0,000 0,06350124 0,08399216 ! oogenesis GO:0048477 44 24 0,000 0,06350124 0,08394671 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,06350124 0,08390131 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,06350124 0,08385596 ! platelet activation GO:0030168 41 24 0,000 0,06350124 0,08381065 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,06350124 0,0837654 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,06350124 0,08372019 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,06350124 0,08367504 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,06350124 0,08362993 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,06350124 0,08358487 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,06350124 0,08353986 ! regulation of amine transport GO:0051952 41 24 0,000 0,06350124 0,0834949 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,06350124 0,08344998 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,06605868 0,08676417 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,06605868 0,08671755 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,06605868 0,08667097 ! leukocyte adhesion GO:0007159 55 25 0,000 0,06605868 0,08662445 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,06605868 0,08657798 ! phototransduction GO:0007602 37 25 0,000 0,06605868 0,08653156 ! keratinization GO:0031424 37 25 0,000 0,06605868 0,08648518 ! vacuole organization GO:0007033 49 25 0,000 0,06605868 0,08643886 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,06605868 0,08639259 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,06605868 0,08634636 ! receptor metabolic process GO:0043112 53 25 0,000 0,06605868 0,08630019 ! chromosome condensation GO:0030261 48 25 0,000 0,06605868 0,08625406 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,06605868 0,08620799 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,06605868 0,08616196 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,06605868 0,08611598 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,06605868 0,08607006 ! immunoglobulin production GO:0002377 62 25 0,000 0,06605868 0,08602418 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,06605868 0,08597835 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,06605868 0,08593256 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,06605868 0,08588683 ! liver development GO:0001889 55 25 0,000 0,06605868 0,08584115 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,06860921 0,08910808 ! myelination GO:0042552 50 26 0,000 0,06860921 0,08906073 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,06860921 0,08901344 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,06860921 0,08896619 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,06860921 0,08891899 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,06860921 0,08887185 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,06860921 0,08882475 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,06860921 0,0887777 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,06860921 0,0887307 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,06860921 0,08868376 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,06860921 0,08863686 ! digestive system process GO:0022600 49 26 0,000 0,06860921 0,08859001 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,06860921 0,08854321 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,06860921 0,08849646 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,06860921 0,08844976 ! osteoblast differentiation GO:0001649 63 26 0,000 0,06860921 0,08840311 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,06860921 0,08835651 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,06860921 0,08830996 ! negative regulation of cell development GO:0010721 83 26 0,000 0,06860921 0,08826346 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,06860921 0,088217 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,06860921 0,0881706 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,06860921 0,08812424 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,06860921 0,08807793 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,06860921 0,08803167 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,06860921 0,08798546 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,06860921 0,0879393 ! blastocyst development GO:0001824 50 26 0,000 0,06860921 0,08789318 ! telomere organization GO:0032200 46 26 0,000 0,06860921 0,08784712 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,06860921 0,0878011 ! neural tube closure GO:0001843 58 26 0,000 0,06860921 0,08775513 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,06860921 0,08770921 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,06860921 0,08766334 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,06860921 0,08761751 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,07115285 0,09081839 ! embryonic pattern specification GO:0009880 49 27 0,000 0,07115285 0,09077097 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,07115285 0,09072359 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,07115285 0,09067627 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,07115285 0,09062899 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,07115285 0,09058177 ! iron ion transport GO:0006826 65 27 0,000 0,07115285 0,09053459 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,07115285 0,09048746 ! superoxide metabolic process GO:0006801 41 27 0,000 0,07115285 0,09044038 ! tube lumen formation GO:0035148 59 27 0,000 0,07115285 0,09039335 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,07115285 0,09034637 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,07115285 0,09029943 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,07115285 0,09025255 ! response to toxin GO:0009636 49 27 0,000 0,07115285 0,09020571 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,07115285 0,09015892 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,07115285 0,09011219 ! leukocyte proliferation GO:0070661 59 27 0,000 0,07115285 0,0900655 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,07115285 0,09001885 ! neuron fate commitment GO:0048663 52 28 0,000 0,07368961 0,09317998 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,07368961 0,09313177 ! vesicle docking GO:0048278 55 28 0,000 0,07368961 0,09308362 ! circadian rhythm GO:0007623 56 28 0,000 0,07368961 0,09303551 ! dendrite development GO:0016358 67 28 0,000 0,07368961 0,09298746 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,07368961 0,09293945 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,07368961 0,09289149 ! sperm motility GO:0030317 37 28 0,000 0,07368961 0,09284359 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,07368961 0,09279573 ! base-excision repair GO:0006284 41 28 0,000 0,07368961 0,09274792 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,07368961 0,09270016 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,07368961 0,09265245 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,07368961 0,09260479 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,07368961 0,09255718 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,07368961 0,09250962 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,07368961 0,0924621 ! glutathione metabolic process GO:0006749 42 28 0,000 0,07368961 0,09241464 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,07368961 0,09236722 ! lipid oxidation GO:0034440 48 28 0,000 0,07368961 0,09231985 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,07368961 0,09227254 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,07368961 0,09222526 ! translational initiation GO:0006413 66 29 0,000 0,07621951 0,09534269 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,07621951 0,0952939 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,07621951 0,09524515 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,07621951 0,09519646 ! autophagy GO:0006914 47 29 0,000 0,07621951 0,09514782 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,07621951 0,09509922 ! primary neural tube formation GO:0014020 61 29 0,000 0,07621951 0,09505068 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,07621951 0,09500218 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,07621951 0,09495374 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,07621951 0,09490534 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,07621951 0,09485699 ! synaptogenesis GO:0007416 46 29 0,000 0,07621951 0,09480869 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,07621951 0,09476045 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,07621951 0,09471225 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,07621951 0,09466409 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,07621951 0,09461599 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,07874258 0,09769839 ! phenol metabolic process GO:0018958 56 30 0,000 0,07874258 0,0976488 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,07874258 0,09759925 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,07874258 0,09754976 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,07874258 0,09750032 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,07874258 0,09745093 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,07874258 0,09740158 ! acute-phase response GO:0006953 50 30 0,000 0,07874258 0,09735229 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,07874258 0,09730305 ! myofibril assembly GO:0030239 50 30 0,000 0,07874258 0,09725386 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,07874258 0,09720471 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,07874258 0,09715562 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,07874258 0,09710658 ! cell fate determination GO:0001709 64 30 0,000 0,07874258 0,09705758 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,07874258 0,09700864 ! phospholipid transport GO:0015914 65 30 0,000 0,07874258 0,09695974 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,07874258 0,09691089 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,07874258 0,0968621 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,07874258 0,09681335 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,07874258 0,09676465 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,07874258 0,096716 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,07874258 0,0966674 ! regulation of coagulation GO:0050818 52 30 0,000 0,07874258 0,09661885 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,08125883 0,09965628 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,08125883 0,09960628 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,08125883 0,09955633 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,08125883 0,09950642 ! cell junction assembly GO:0034329 85 31 0,000 0,08125883 0,09945657 ! regulation of innate immune response GO:0045088 57 31 0,000 0,08125883 0,09940677 ! ovulation cycle process GO:0022602 55 31 0,000 0,08125883 0,09935701 ! peptide transport GO:0015833 60 31 0,000 0,08125883 0,09930731 ! male gonad development GO:0008584 56 31 0,000 0,08125883 0,09925766 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,08125883 0,09920805 ! detection of light stimulus GO:0009583 44 31 0,000 0,08125883 0,0991585 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,08125883 0,09910899 ! natural killer cell activation GO:0030101 50 31 0,000 0,08125883 0,09905954 ! ensheathment of neurons GO:0007272 64 31 0,000 0,08125883 0,09901013 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,08125883 0,09896078 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,08125883 0,09891147 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,08125883 0,09886221 ! eye morphogenesis GO:0048592 65 31 0,000 0,08125883 0,098813 ! response to heat GO:0009408 54 31 0,000 0,08125883 0,09876384 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,08125883 0,09871473 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,08376827 0,10171267 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,08376827 0,10166214 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,08376827 0,10161166 ! spindle organization GO:0007051 50 32 0,000 0,08376827 0,10156123 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,08376827 0,10151086 ! metanephros development GO:0001656 81 32 0,000 0,08376827 0,10146053 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,08376827 0,10141025 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,08376827 0,10136002 ! muscle cell development GO:0055001 52 32 0,000 0,08376827 0,10130985 ! mesoderm formation GO:0001707 73 32 0,000 0,08376827 0,10125972 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,08376827 0,10120964 ! ovulation cycle GO:0042698 57 32 0,000 0,08376827 0,10115961 ! peripheral nervous system development GO:0007422 68 32 0,000 0,08376827 0,10110963 ! BMP signaling pathway GO:0030509 71 32 0,000 0,08376827 0,1010597 ! hindbrain development GO:0030902 65 32 0,000 0,08376827 0,10100982 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,08376827 0,10095998 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,08376827 0,1009102 ! gene silencing GO:0016458 71 32 0,000 0,08376827 0,10086047 ! regulation of pH GO:0006885 56 33 0,000 0,08627093 0,1038226 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,08627093 0,10377149 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,08627093 0,10372042 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,08627093 0,1036694 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,08627093 0,10361843 ! response to ionizing radiation GO:0010212 74 33 0,000 0,08627093 0,10356751 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,08627093 0,10351664 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,08627093 0,10346583 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,08627093 0,10341506 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,08627093 0,10336434 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,08627093 0,10331367 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,08627093 0,10326305 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,08876683 0,10619851 ! glial cell differentiation GO:0010001 67 34 0,000 0,08876683 0,10614653 ! post-embryonic development GO:0009791 76 34 0,000 0,08876683 0,1060946 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,08876683 0,10604272 ! cholesterol transport GO:0030301 62 34 0,000 0,08876683 0,10599089 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,08876683 0,10593911 ! spliceosome assembly GO:0000245 75 34 0,000 0,08876683 0,10588738 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,08876683 0,1058357 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,08876683 0,10578408 ! formation of primary germ layer GO:0001704 76 34 0,000 0,08876683 0,1057325 ! cell fate specification GO:0001708 56 34 0,000 0,08876683 0,10568097 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,08876683 0,1056295 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,08876683 0,10557807 ! adult locomotory behavior GO:0008344 62 34 0,000 0,08876683 0,1055267 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,09125597 0,10843305 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,09125597 0,10838033 ! negative regulation of secretion GO:0051048 68 35 0,000 0,09125597 0,10832767 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,09125597 0,10827506 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,09125597 0,1082225 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,09125597 0,10816999 ! membrane docking GO:0022406 69 35 0,000 0,09125597 0,10811753 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,09125597 0,10806512 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,09125597 0,10801276 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,09125597 0,10796046 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,09125597 0,1079082 ! ceramide metabolic process GO:0006672 72 35 0,000 0,09125597 0,107856 ! telencephalon development GO:0021537 81 35 0,000 0,09125597 0,10780384 ! sterol transport GO:0015918 63 35 0,000 0,09125597 0,10775174 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,09125597 0,10769968 ! vesicle localization GO:0051648 70 35 0,000 0,09125597 0,10764768 ! regulation of muscle development GO:0048634 82 36 0,000 0,09373839 0,11052263 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,09373839 0,11046932 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,09373839 0,11041605 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,09373839 0,11036284 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,09373839 0,11030968 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,09373839 0,11025657 ! positive regulation of cell development GO:0010720 85 36 0,000 0,09373839 0,11020351 ! protein targeting to membrane GO:0006612 75 36 0,000 0,09373839 0,1101505 ! regulation of proteolysis GO:0030162 77 36 0,000 0,09373839 0,11009754 ! aerobic respiration GO:0009060 56 36 0,000 0,09373839 0,11004464 ! cytokine production GO:0001816 68 36 0,000 0,09373839 0,10999178 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,09373839 0,10993898 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,09373839 0,10988622 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,0962141 0,11273431 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,0962141 0,11268027 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,0962141 0,11262628 ! sister chromatid segregation GO:0000819 65 37 0,000 0,0962141 0,11257234 ! odontogenesis GO:0042476 74 37 0,000 0,0962141 0,11251845 ! actomyosin structure organization GO:0031032 68 37 0,000 0,0962141 0,11246461 ! cell junction organization GO:0034330 96 37 0,000 0,0962141 0,11241083 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,0962141 0,11235709 ! female gonad development GO:0008585 71 37 0,000 0,0962141 0,11230341 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,0962141 0,11224978 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,0962141 0,1121962 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,0962141 0,11214267 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,09868311 0,11496559 ! meiosis I GO:0007127 74 38 0,000 0,09868311 0,11491079 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,09868311 0,11485605 ! organic anion transport GO:0015711 82 38 0,000 0,09868311 0,11480135 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,09868311 0,11474671 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,09868311 0,11469212 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,09868311 0,11463758 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,09868311 0,1145831 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,09868311 0,11452867 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,09868311 0,11447428 ! regulation of protein stability GO:0031647 77 38 0,000 0,09868311 0,11441995 ! spermatid development GO:0007286 69 38 0,000 0,09868311 0,11436567 ! glycogen metabolic process GO:0005977 63 38 0,000 0,09868311 0,11431145 ! pigment metabolic process GO:0042440 87 38 0,000 0,09868311 0,11425727 ! neural tube formation GO:0001841 79 38 0,000 0,09868311 0,11420315 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,10114545 0,11699731 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,10114545 0,11694194 ! negative regulation of binding GO:0051100 71 39 0,000 0,10114545 0,11688663 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,10114545 0,11683136 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,10114545 0,11677615 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,10114545 0,11672099 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,10114545 0,11666588 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,10114545 0,11661082 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,10114545 0,11655582 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,10114545 0,11650086 ! glucan metabolic process GO:0044042 64 39 0,000 0,10114545 0,11644596 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 0,000 0,10360113 0,11921694 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,10360113 0,11916081 ! learning GO:0007612 82 40 0,000 0,10360113 0,11910473 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,10360113 0,11904871 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,10360113 0,11899274 ! lipid homeostasis GO:0055088 75 40 0,000 0,10360113 0,11893682 ! mismatch repair GO:0006298 58 40 0,000 0,10360113 0,11888096 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,10360113 0,11882514 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,10360113 0,11876938 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,10360113 0,11871367 ! RNA export from nucleus GO:0006405 61 41 0,000 0,10605017 0,12146299 ! mRNA catabolic process GO:0006402 79 41 0,000 0,10605017 0,12140607 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,10605017 0,12134921 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,10605017 0,1212924 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,10605017 0,12123564 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,10605017 0,12117893 ! feeding behavior GO:0007631 69 41 0,000 0,10605017 0,12112228 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,10605017 0,12106568 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,10605017 0,12100913 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,10605017 0,12095264 ! spermatid differentiation GO:0048515 73 41 0,000 0,10605017 0,1208962 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,10605017 0,12083981 ! RNA modification GO:0009451 64 41 0,000 0,10605017 0,12078348 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,10849258 0,12350763 ! ear morphogenesis GO:0042471 64 42 0,000 0,10849258 0,12345011 ! organic ether metabolic process GO:0018904 59 42 0,000 0,10849258 0,12339264 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,10849258 0,12333522 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,10849258 0,12327785 ! T cell differentiation GO:0030217 93 42 0,000 0,10849258 0,12322054 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,10849258 0,12316328 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,10849258 0,12310608 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,10849258 0,12304892 ! regulation of protein secretion GO:0050708 77 42 0,000 0,10849258 0,12299182 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,10849258 0,12293478 ! cytokinesis GO:0000910 84 42 0,000 0,10849258 0,12287778 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,10849258 0,12282084 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,1109284 0,12552018 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,1109284 0,12546207 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,1109284 0,12540401 ! regulation of tube size GO:0035150 76 43 0,000 0,1109284 0,12534601 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,1109284 0,12528806 ! glucose transport GO:0015758 66 43 0,000 0,1109284 0,12523016 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,1109284 0,12517232 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,1109284 0,12511453 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,1109284 0,12505679 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,1109284 0,12499911 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,1109284 0,12494148 ! ion transmembrane transport GO:0034220 79 43 0,000 0,1109284 0,1248839 ! neuron migration GO:0001764 85 43 0,000 0,1109284 0,12482638 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,11335762 0,12750123 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,11335762 0,12744255 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,11335762 0,12738393 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,11335762 0,12732537 ! hexose transport GO:0008645 68 44 0,000 0,11335762 0,12726685 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,11335762 0,12720839 ! striated muscle contraction GO:0006941 85 44 0,000 0,11335762 0,12714999 ! phagocytosis GO:0006909 105 44 0,000 0,11335762 0,12709163 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,11335762 0,12703334 ! double-strand break repair GO:0006302 85 44 0,000 0,11335762 0,12697509 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,11578028 0,12962934 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,11578028 0,12956996 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,11578028 0,12951063 ! B cell differentiation GO:0030183 124 45 0,000 0,11578028 0,12945136 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,11578028 0,12939214 ! female gamete generation GO:0007292 71 45 0,000 0,11578028 0,12933298 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,11578028 0,12927387 ! polyol metabolic process GO:0019751 77 45 0,000 0,11578028 0,12921481 ! developmental growth GO:0048589 88 45 0,000 0,11578028 0,12915581 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,11819638 0,13179086 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,11819638 0,13173073 ! glycolysis GO:0006096 71 46 0,000 0,11819638 0,13167066 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,11819638 0,13161065 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,11819638 0,13155069 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,11819638 0,13149079 ! pigmentation GO:0043473 103 46 0,000 0,11819638 0,13143094 ! cell growth GO:0016049 90 46 0,000 0,11819638 0,13137114 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,11819638 0,1313114 ! neural tube development GO:0021915 91 47 0,000 0,12060595 0,13392743 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,12060595 0,13386658 ! positive regulation of defense response GO:0031349 88 48 0,000 0,12300901 0,13647185 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,12300901 0,1364099 ! mitochondrial transport GO:0006839 94 48 0,000 0,12300901 0,13634801 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,12300901 0,13628617 ! cellular component disassembly GO:0022411 89 48 0,000 0,12300901 0,13622439 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,12300901 0,13616267 ! endosome transport GO:0016197 127 48 0,000 0,12300901 0,136101 ! male sex differentiation GO:0046661 93 48 0,000 0,12300901 0,13603939 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,12300901 0,13597783 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,12300901 0,13591633 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,12300901 0,13585489 ! methylation GO:0032259 97 48 0,000 0,12300901 0,1357935 ! response to calcium ion GO:0051592 94 49 0,000 0,12540556 0,1383766 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,12540556 0,13831413 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,12540556 0,13825171 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,12540556 0,13818935 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,12540556 0,13812705 ! protein homooligomerization GO:0051260 84 49 0,000 0,12540556 0,1380648 ! regulation of action potential GO:0001508 102 50 0,000 0,12779564 0,14063277 ! regulation of ion transport GO:0043269 86 50 0,000 0,12779564 0,14056945 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,12779564 0,14050619 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,12779564 0,14044298 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,12779564 0,14037983 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,12779564 0,14031674 ! peptide metabolic process GO:0006518 80 51 0,000 0,13017925 0,14286968 ! response to temperature stimulus GO:0009266 84 51 0,000 0,13017925 0,14280552 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,13017925 0,14274143 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,13017925 0,14267739 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,13255641 0,14521763 ! Notch signaling pathway GO:0007219 111 52 0,000 0,13255641 0,14515254 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,13255641 0,1450875 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,13255641 0,14502253 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,13255641 0,14495761 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,13255641 0,14489275 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,13255641 0,14482795 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,13255641 0,14476321 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,13255641 0,14469853 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,13255641 0,1446339 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,13492714 0,14715491 ! inner ear development GO:0048839 89 53 0,000 0,13492714 0,14708925 ! chromatin remodeling GO:0006338 122 53 0,000 0,13492714 0,14702364 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,13492714 0,14695809 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,13492714 0,14689261 ! vesicle organization GO:0016050 127 53 0,000 0,13492714 0,14682717 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,13492714 0,1467618 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,13492714 0,14669649 ! synapse organization GO:0050808 102 53 0,000 0,13492714 0,14663123 ! regulation of translational initiation GO:0006446 87 54 0,000 0,13729146 0,1491343 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,13729146 0,14906802 ! neuromuscular process GO:0050905 107 54 0,000 0,13729146 0,14900179 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,13729146 0,14893563 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,13729146 0,14886952 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,13729146 0,14880348 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,13729146 0,14873749 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,13729146 0,14867156 ! RNA catabolic process GO:0006401 103 55 0,000 0,13964939 0,15115793 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,13964939 0,15109099 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,13964939 0,1510241 ! cell recognition GO:0008037 98 55 0,000 0,13964939 0,15095728 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,13964939 0,15089051 ! cell maturation GO:0048469 107 55 0,000 0,13964939 0,15082381 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,13964939 0,15075716 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,14200093 0,15322804 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,14200093 0,15316039 ! glucose catabolic process GO:0006007 88 56 0,000 0,14200093 0,1530928 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,14200093 0,15302526 ! RNA elongation GO:0006354 90 56 0,000 0,14200093 0,15295779 ! chloride transport GO:0006821 102 57 0,000 0,14434612 0,15541541 ! muscle fiber development GO:0048747 131 57 0,000 0,14434612 0,15534694 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,14434612 0,15527854 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,14434612 0,15521019 ! regulation of actin filament length GO:0030832 118 58 0,000 0,14668496 0,15765567 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,14668496 0,15758634 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,14668496 0,15751708 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,14668496 0,15744787 ! aging GO:0007568 112 58 0,000 0,14668496 0,15737872 ! gastrulation GO:0007369 122 58 0,000 0,14668496 0,15730963 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,14668496 0,15724061 ! nuclear export GO:0051168 110 59 0,000 0,14901747 0,15967091 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,15134367 0,16209232 ! DNA catabolic process GO:0006308 94 60 0,000 0,15134367 0,16202129 ! regulation of endocytosis GO:0030100 104 60 0,000 0,15134367 0,16195032 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,15134367 0,16187942 ! adult behavior GO:0030534 104 60 0,000 0,15134367 0,16180857 ! kidney development GO:0001822 133 60 0,000 0,15134367 0,16173779 ! positive regulation of secretion GO:0051047 110 61 0,000 0,15366358 0,16414522 ! regulation of cellular component size GO:0032535 125 61 0,000 0,15366358 0,16407348 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,15366358 0,1640018 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,15366358 0,16393019 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,15366358 0,16385863 ! regulation of heart contraction GO:0008016 123 61 0,000 0,15366358 0,16378714 ! camera-type eye development GO:0043010 126 61 0,000 0,15366358 0,16371571 ! proton transport GO:0015992 117 61 0,000 0,15366358 0,16364435 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,15597721 0,16603588 ! tRNA processing GO:0008033 102 62 0,000 0,15597721 0,16596356 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,15828459 0,16834534 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,15828459 0,16827208 ! hydrogen transport GO:0006818 121 64 0,000 0,16058572 0,17064415 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,16058572 0,17056996 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,16058572 0,17049583 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,16288062 0,17285724 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,16288062 0,17278218 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,16288062 0,17270719 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,16288062 0,17263226 ! ear development GO:0043583 114 66 0,000 0,16516931 0,17498206 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,16516931 0,17490621 ! gonad development GO:0008406 115 66 0,000 0,16516931 0,17483043 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,16745182 0,17716968 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,16745182 0,17709298 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,16745182 0,17701635 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,16745182 0,17693979 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,16745182 0,17686329 ! secondary metabolic process GO:0019748 125 67 0,000 0,16745182 0,17678686 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,16972814 0,17911268 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,16972814 0,17903534 ! hexose catabolic process GO:0019320 113 68 0,000 0,16972814 0,17895807 ! extracellular matrix organization GO:0030198 146 68 0,000 0,16972814 0,17888087 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,16972814 0,17880373 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,16972814 0,17872666 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,16972814 0,17864965 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,16972814 0,17857272 ! negative regulation of cell size GO:0045792 144 69 0,000 0,17199831 0,18088328 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,17199831 0,18080545 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,17199831 0,18072768 ! urogenital system development GO:0001655 149 69 0,000 0,17199831 0,18064998 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,17199831 0,18057235 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,17199831 0,18049479 ! developmental maturation GO:0021700 128 69 0,000 0,17199831 0,18041729 ! single fertilization GO:0007338 83 69 0,000 0,17199831 0,18033985 ! germ cell development GO:0007281 133 70 0,000 0,17426233 0,18263529 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,17652022 0,18492234 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,17652022 0,18484308 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,17652022 0,18476388 ! appendage morphogenesis GO:0035107 150 72 0,000 0,17877201 0,18704069 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,17877201 0,18696062 ! actin filament organization GO:0007015 167 72 0,000 0,17877201 0,18688062 ! B cell activation GO:0042113 179 72 0,000 0,17877201 0,18680069 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,17877201 0,18672083 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,17877201 0,18664103 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,17877201 0,1865613 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,17877201 0,18648164 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,17877201 0,18640205 ! appendage development GO:0048736 151 73 0,000 0,1810177 0,18866307 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,1810177 0,18858261 ! regulation of immune effector process GO:0002697 156 73 0,000 0,1810177 0,18850223 ! amino acid transport GO:0006865 148 74 0,000 0,18325731 0,19075313 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,18325731 0,19067189 ! transition metal ion transport GO:0000041 143 75 0,000 0,18549086 0,19291365 ! reproductive structure development GO:0048608 131 75 0,000 0,18549086 0,19283156 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,18549086 0,19274954 ! eye development GO:0001654 155 75 0,000 0,18549086 0,19266759 ! axon guidance GO:0007411 162 75 0,000 0,18549086 0,19258571 ! rhythmic process GO:0048511 142 75 0,000 0,18549086 0,19250389 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,18771836 0,19473289 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,18771836 0,19465024 ! learning or memory GO:0007611 161 76 0,000 0,18771836 0,19456766 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,18771836 0,19448514 ! regulation of blood pressure GO:0008217 134 76 0,000 0,18771836 0,1944027 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,18771836 0,19432032 ! amine catabolic process GO:0009310 136 77 0,000 0,18993984 0,19653665 ! neurotransmitter transport GO:0006836 142 77 0,000 0,18993984 0,19645344 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,18993984 0,1963703 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,18993984 0,19628724 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,18993984 0,19620424 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,18993984 0,19612131 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,1921553 0,19832506 ! antigen processing and presentation GO:0019882 117 78 0,000 0,1921553 0,1982413 ! fertilization GO:0009566 99 78 0,000 0,1921553 0,19815762 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,1921553 0,19807401 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,19436477 0,20026703 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,19436477 0,2001826 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,19436477 0,20009824 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,19436477 0,20001396 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,19436477 0,19992974 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,19656826 0,20211122 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,19656826 0,20202619 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,19656826 0,20194123 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,19656826 0,20185635 ! meiosis GO:0007126 143 81 0,000 0,19876578 0,20402722 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,19876578 0,20394153 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,19876578 0,20385592 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,20095735 0,20601712 ! meiotic cell cycle GO:0051321 144 82 0,000 0,20095735 0,20593071 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,20314299 0,20808315 ! exocytosis GO:0006887 153 83 0,000 0,20314299 0,20799594 ! response to drug GO:0042493 149 83 0,000 0,20314299 0,20790881 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,20314299 0,20782174 ! inorganic anion transport GO:0015698 156 83 0,000 0,20314299 0,20773475 ! response to metal ion GO:0010038 158 84 0,000 0,20532271 0,20987589 ! T cell activation GO:0042110 189 84 0,000 0,20532271 0,20978811 ! digestion GO:0007586 130 84 0,000 0,20532271 0,20970041 ! regulation of ligase activity GO:0051340 147 84 0,000 0,20532271 0,20961278 ! negative regulation of transport GO:0051051 164 85 0,000 0,20749653 0,21174354 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,20749653 0,21165513 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,20749653 0,21156679 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,20749653 0,21147853 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,20749653 0,21139034 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,20966447 0,21350992 ! regulation of lyase activity GO:0051339 169 86 0,000 0,20966447 0,21342096 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,20966447 0,21333207 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,21182653 0,21544222 ! alcohol catabolic process GO:0046164 142 87 0,000 0,21182653 0,21535257 ! nucleosome assembly GO:0006334 126 87 0,000 0,21182653 0,21526299 ! regulation of protein transport GO:0051223 165 87 0,000 0,21182653 0,21517348 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,21398275 0,21727342 ! amine biosynthetic process GO:0009309 146 88 0,000 0,21398275 0,21718315 ! sensory perception of smell GO:0007608 117 88 0,000 0,21398275 0,21709296 ! chromatin assembly GO:0031497 128 88 0,000 0,21398275 0,21700284 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,21398275 0,2169128 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,21613312 0,21900175 ! tube morphogenesis GO:0035239 194 89 0,000 0,21613312 0,21891095 ! cellular defense response GO:0006968 123 89 0,000 0,21613312 0,21882023 ! regulation of neurological system process GO:0031644 175 89 0,000 0,21613312 0,21872958 ! response to inorganic substance GO:0010035 173 90 0,000 0,21827767 0,22080843 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,21827767 0,22071703 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,21827767 0,22062571 ! response to unfolded protein GO:0006986 139 90 0,000 0,21827767 0,22053447 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,22041642 0,22260327 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,22041642 0,22251128 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,22254937 0,22457171 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,22467655 0,22662461 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,22467655 0,22653108 ! vitamin metabolic process GO:0006766 153 93 0,000 0,22467655 0,22643763 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,22679797 0,22848141 ! female pregnancy GO:0007565 166 94 0,000 0,22679797 0,22838723 ! sterol metabolic process GO:0016125 166 94 0,000 0,22679797 0,22829313 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,22679797 0,22819911 ! regulation of membrane potential GO:0042391 179 94 0,000 0,22679797 0,22810516 ! nucleosome organization GO:0034728 143 95 0,000 0,22891364 0,23013828 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,22891364 0,23004361 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,22891364 0,22994902 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,22891364 0,22985451 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,22891364 0,22976007 ! sex differentiation GO:0007548 171 96 0,000 0,23102358 0,23178259 ! response to protein stimulus GO:0051789 158 96 0,000 0,23102358 0,23168744 ! regulation of T cell activation GO:0050863 175 96 0,000 0,23102358 0,23159237 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,23312781 0,23360592 ! transcription initiation GO:0006352 171 97 0,000 0,23312781 0,23351014 ! regulation of protein localization GO:0032880 188 97 0,000 0,23312781 0,23341444 ! forebrain development GO:0030900 210 98 0,000 0,23522634 0,23541907 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,23522634 0,23532267 ! hormone metabolic process GO:0042445 171 100 0,000 0,23940637 0,23940637