pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1126-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 4,000 1,542E-10 3,71E-07 ! Notch receptor processing GO:0007220 8 5 2,000 4,846E-07 5,83E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 9,667E-07 7,753E-04 ! nuclear migration GO:0007097 12 6 2,000 9,667E-07 5,814E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 9,667E-07 4,652E-04 GO:0031272|regulation of pseudopodium assembly, ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 4,000 1,274E-06 5,11E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 1,687E-06 5,799E-04 ! amyloid precursor protein catabolic process GO:0042987 11 7 2,000 1,687E-06 5,074E-04 ! macrophage differentiation GO:0030225 11 7 2,000 1,687E-06 4,51E-04 ! RNA elongation GO:0006354 79 55 4,000 1,865E-06 4,488E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 2,692E-06 5,888E-04 ! regulation of vascular permeability GO:0043114 12 8 2,000 2,692E-06 5,398E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 2,692E-06 4,982E-04 ! amyloid precursor protein metabolic process GO:0042982 14 9 2,000 4,027E-06 6,921E-04 ! protein sumoylation GO:0016925 15 10 2,000 5,738E-06 9,203E-04 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 7,868E-06 1,183E-03 ! nucleus localization GO:0051647 19 11 2,000 7,868E-06 1,114E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 1,046E-05 1,399E-03 ! membrane protein proteolysis GO:0033619 25 12 2,000 1,046E-05 1,325E-03 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of hormone metabolic process GO:0032350 26 12 2,000 1,046E-05 1,259E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 3,000 1,051E-05 1,204E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 4,000 1,058E-05 1,157E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 1,171E-05 1,225E-03 GO:0042593|glucose homeostasis, ! cGMP metabolic process GO:0046068 18 13 2,000 1,357E-05 1,36E-03 GO:0006182|cGMP biosynthetic process, ! glycoprotein catabolic process GO:0006516 26 15 2,000 2,147E-05 2,066E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 2,147E-05 1,986E-03 ! branching morphogenesis of a tube GO:0048754 97 45 3,000 2,317E-05 2,065E-03 ! transcription initiation GO:0006352 153 94 4,000 2,626E-05 2,256E-03 ! filopodium assembly GO:0046847 32 16 2,000 2,635E-05 2,186E-03 ! myoblast differentiation GO:0045445 45 17 2,000 3,191E-05 2,559E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 3,191E-05 2,476E-03 ! microspike assembly GO:0030035 36 17 2,000 3,191E-05 2,399E-03 ! patterning of blood vessels GO:0001569 39 18 2,000 3,819E-05 2,784E-03 ! response to retinoic acid GO:0032526 26 18 2,000 3,819E-05 2,702E-03 ! regulation of cell shape GO:0008360 125 51 3,000 3,821E-05 2,627E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 4,128E-05 2,759E-03 ! morphogenesis of a branching structure GO:0001763 111 52 3,000 4,128E-05 2,684E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 4,523E-05 2,863E-03 ! response to vitamin A GO:0033189 27 19 2,000 4,523E-05 2,79E-03 ! response to vitamin GO:0033273 31 20 2,000 5,306E-05 3,192E-03 ! pancreas development GO:0031016 35 20 2,000 5,306E-05 3,114E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 5,306E-05 3,04E-03 ! negative regulation of angiogenesis GO:0016525 45 20 2,000 5,306E-05 2,969E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 5,938E-05 3,247E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 8,177E-05 4,372E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 8,177E-05 4,277E-03 ! platelet activation GO:0030168 37 23 2,000 8,177E-05 4,186E-03 ! viral reproductive process GO:0022415 126 62 3,000 8,268E-05 4,144E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 8,804E-05 4,323E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 9,364E-05 4,506E-03 ! regulation of insulin secretion GO:0050796 37 25 2,000 1,056E-04 4,983E-03 ! interaction with host GO:0051701 62 25 2,000 1,056E-04 4,887E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 1,187E-04 5,387E-03 ! viral reproduction GO:0016032 134 68 3,000 1,187E-04 5,287E-03 ! initiation of viral infection GO:0019059 57 26 2,000 1,191E-04 5,21E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 1,191E-04 5,117E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 1,336E-04 5,64E-03 ! fat cell differentiation GO:0045444 50 27 2,000 1,336E-04 5,543E-03 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 2,000 1,336E-04 5,449E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,336E-04 5,359E-03 ! protein maturation by protein folding GO:0022417 13 5 1,000 1,336E-04 5,271E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,336E-04 5,186E-03 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 1,336E-04 5,104E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,336E-04 5,024E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,336E-04 4,947E-03 ! sequestering of calcium ion GO:0051208 7 5 1,000 1,336E-04 4,872E-03 ! regulation of caspase activity GO:0043281 122 72 3,000 1,482E-04 5,323E-03 ! regulation of blood pressure GO:0008217 125 73 3,000 1,564E-04 5,533E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 1,648E-04 5,748E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 1,66E-04 5,706E-03 ! regulation of peptide secretion GO:0002791 47 29 2,000 1,66E-04 5,626E-03 ! male sex determination GO:0030238 15 6 1,000 2E-04 6,683E-03 ! neuronal ion channel clustering GO:0045161 12 6 1,000 2E-04 6,591E-03 ! triglyceride catabolic process GO:0019433 10 6 1,000 2E-04 6,502E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 2,122E-04 6,809E-03 ! response to hypoxia GO:0001666 171 81 3,000 2,337E-04 7,398E-03 ! response to oxygen levels GO:0070482 176 83 3,000 2,567E-04 8,02E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 2,683E-04 8,275E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,793E-04 8,507E-03 ! mRNA stabilization GO:0048255 18 7 1,000 2,793E-04 8,4E-03 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 2,793E-04 8,296E-03 GO:0031958|corticosteroid receptor signaling pathway, ! glycerol ether catabolic process GO:0044269 12 7 1,000 2,793E-04 8,195E-03 GO:0046464|acylglycerol catabolic process, ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 1,000 2,793E-04 8,097E-03 ! regulation of meiosis GO:0040020 12 7 1,000 2,793E-04 8E-03 GO:0051445|regulation of meiotic cell cycle, ! regulation of respiratory burst GO:0060263 11 7 1,000 2,793E-04 7,906E-03 ! diuresis GO:0030146 12 7 1,000 2,793E-04 7,814E-03 GO:0030147|natriuresis, ! tube morphogenesis GO:0035239 176 86 3,000 2,941E-04 8,133E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 3,184E-04 8,705E-03 ! regulation of cell morphogenesis GO:0022604 215 89 3,000 3,353E-04 9,064E-03 ! cyclic nucleotide metabolic process GO:0009187 63 37 2,000 3,455E-04 9,238E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 3,455E-04 9,136E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,715E-04 9,716E-03 ! neutral lipid catabolic process GO:0046461 13 8 1,000 3,715E-04 9,611E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 3,715E-04 9,509E-03 ! glycerolipid catabolic process GO:0046503 13 8 1,000 3,715E-04 9,409E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,715E-04 9,311E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 3,715E-04 9,215E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 3,715E-04 9,121E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 1,000 3,715E-04 9,029E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 3,715E-04 8,939E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 3,742E-04 8,913E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 3,964E-04 9,351E-03 ! regulation of hormone secretion GO:0046883 62 40 2,000 4,359E-04 0,01018137 ! mesenchymal cell development GO:0014031 87 40 2,000 4,359E-04 0,01008348 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of developmental growth GO:0048638 15 9 1,000 4,765E-04 0,01091886 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 4,765E-04 0,01081585 ! induction of positive chemotaxis GO:0050930 15 9 1,000 4,765E-04 0,01071477 ! regulation of glycolysis GO:0006110 21 9 1,000 4,765E-04 0,01061556 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 4,765E-04 0,01051816 ! motor axon guidance GO:0008045 16 9 1,000 4,765E-04 0,01042255 ! protein heterooligomerization GO:0051291 16 9 1,000 4,765E-04 0,01032865 ! renal water homeostasis GO:0003091 14 9 1,000 4,765E-04 0,01023643 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 4,765E-04 0,01014584 ! skeletal muscle tissue development GO:0007519 186 99 3,000 5,025E-04 0,01060621 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 3,000 5,22E-04 0,01092122 ! lung alveolus development GO:0048286 26 10 1,000 5,942E-04 0,01232456 ! regulation of bone resorption GO:0045124 25 10 1,000 5,942E-04 0,01221922 ! positive regulation of phagocytosis GO:0050766 13 10 1,000 5,942E-04 0,01211567 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 1,000 5,942E-04 0,01201385 ! apical protein localization GO:0045176 15 10 1,000 5,942E-04 0,01191374 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 5,942E-04 0,01181528 ! multicellular organismal water homeostasis GO:0050891 15 10 1,000 5,942E-04 0,01171843 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 5,942E-04 0,01162316 GO:0043470|regulation of carbohydrate catabolic process, ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 1,000 5,942E-04 0,01152942 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 5,942E-04 0,01143719 ! localization within membrane GO:0051668 20 10 1,000 5,942E-04 0,01134642 ! response to insulin stimulus GO:0032868 95 46 2,000 6,59E-04 0,01248474 ! vascular process in circulatory system GO:0003018 80 47 2,000 7,021E-04 0,01319644 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 7,245E-04 0,01351272 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 7,245E-04 0,01340878 ! T cell proliferation GO:0042098 26 11 1,000 7,245E-04 0,01330642 ! blood vessel remodeling GO:0001974 29 11 1,000 7,245E-04 0,01320562 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 7,245E-04 0,01310633 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 7,245E-04 0,01300852 ! DNA methylation GO:0006306 19 11 1,000 7,245E-04 0,01291216 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 7,245E-04 0,01281722 ! germ cell migration GO:0008354 25 11 1,000 7,245E-04 0,01272366 ! sequestering of metal ion GO:0051238 14 11 1,000 7,245E-04 0,01263146 ! regulation of embryonic development GO:0045995 27 11 1,000 7,245E-04 0,01254059 ! positive regulation of cell cycle GO:0045787 89 48 2,000 7,469E-04 0,01283529 ! Notch signaling pathway GO:0007219 96 48 2,000 7,469E-04 0,01274426 ! activation of caspase activity GO:0006919 84 48 2,000 7,469E-04 0,01265451 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 7,934E-04 0,01334979 ! regulation of cell projection organization GO:0031344 121 50 2,000 8,418E-04 0,01406561 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 8,673E-04 0,01439128 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 8,673E-04 0,01429271 ! virus-host interaction GO:0019048 29 12 1,000 8,673E-04 0,01419548 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 8,673E-04 0,01409956 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 8,673E-04 0,01400493 ! asymmetric protein localization GO:0008105 20 12 1,000 8,673E-04 0,01391157 ! entry into host cell GO:0030260 32 12 1,000 8,673E-04 0,01381944 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 16 12 1,000 8,673E-04 0,01372852 ! histone acetylation GO:0016573 26 12 1,000 8,673E-04 0,01363879 ! peptidyl-lysine modification GO:0018205 21 12 1,000 8,673E-04 0,01355023 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 8,673E-04 0,01346281 ! viral infectious cycle GO:0019058 99 51 2,000 8,921E-04 0,01375829 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 2,000 9,981E-04 0,0152961 ! response to UV GO:0009411 104 53 2,000 9,981E-04 0,01519929 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,023E-03 0,015473 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,023E-03 0,01537629 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,023E-03 0,01528079 ! regulation of mRNA stability GO:0043488 31 13 1,000 1,023E-03 0,01518646 ! activation of phospholipase C activity GO:0007202 103 54 2,000 1,054E-03 0,01555808 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 2,000 1,112E-03 0,01631168 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 1,112E-03 0,01621282 ! aging GO:0007568 103 55 2,000 1,112E-03 0,01611515 ! skeletal muscle fiber development GO:0048741 111 56 2,000 1,172E-03 0,01688021 ! regulation of DNA replication GO:0006275 101 56 2,000 1,172E-03 0,01677974 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,19E-03 0,01694282 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 1,19E-03 0,01684316 GO:0060675|ureteric bud morphogenesis, ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 1,19E-03 0,01674466 ! regulation of RNA stability GO:0043487 32 14 1,000 1,19E-03 0,01664731 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 1,233E-03 0,01715416 ! muscle fiber development GO:0048747 112 57 2,000 1,233E-03 0,01705557 ! regulation of phospholipase activity GO:0010517 106 57 2,000 1,233E-03 0,01695811 ! positive regulation of lipase activity GO:0060193 108 58 2,000 1,297E-03 0,01773407 ! positive regulation of secretion GO:0051047 95 59 2,000 1,363E-03 0,018529 ! establishment of organelle localization GO:0051656 109 59 2,000 1,363E-03 0,01842491 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,37E-03 0,01841288 ! regulation of vasodilation GO:0042312 26 15 1,000 1,37E-03 0,01831058 ! water homeostasis GO:0030104 27 15 1,000 1,37E-03 0,01820942 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 1,431E-03 0,01891781 ! regulation of protein complex assembly GO:0043254 117 61 2,000 1,501E-03 0,01973485 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 1,501E-03 0,01962759 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,562E-03 0,02031185 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,562E-03 0,02020265 ! DNA replication initiation GO:0006270 27 16 1,000 1,562E-03 0,02009461 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,562E-03 0,01998773 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,562E-03 0,01988197 ! regulation of homeostatic process GO:0032844 134 62 2,000 1,573E-03 0,01992103 ! nucleoside monophosphate metabolic process GO:0009123 107 63 2,000 1,647E-03 0,02075212 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 1,647E-03 0,02064404 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 1,766E-03 0,02201286 ! DNA unwinding during replication GO:0006268 27 17 1,000 1,766E-03 0,02189939 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,766E-03 0,02178709 ! myeloid cell differentiation GO:0030099 111 65 2,000 1,802E-03 0,02212557 ! cell projection assembly GO:0030031 120 66 2,000 1,883E-03 0,02300008 ! activation of MAPK activity GO:0000187 115 67 2,000 1,966E-03 0,0238928 ! lung development GO:0030324 144 67 2,000 1,966E-03 0,02377274 ! neuron maturation GO:0042551 42 18 1,000 1,982E-03 0,02384029 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,982E-03 0,02372168 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,982E-03 0,02360425 ! regulation of lipase activity GO:0060191 130 68 2,000 2,052E-03 0,02431498 ! protein maturation by peptide bond cleavage GO:0051605 105 68 2,000 2,052E-03 0,02419579 ! lipid phosphorylation GO:0046834 35 19 1,000 2,21E-03 0,0259327 ! plasma membrane fusion GO:0045026 28 19 1,000 2,21E-03 0,02580682 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 2,21E-03 0,02568215 ! protein export from nucleus GO:0006611 36 19 1,000 2,21E-03 0,02555867 ! cellular pigmentation GO:0033059 36 19 1,000 2,21E-03 0,02543638 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 2,21E-03 0,02531526 ! respiratory tube development GO:0030323 150 70 2,000 2,229E-03 0,02541561 ! respiratory system development GO:0060541 153 72 2,000 2,415E-03 0,02741356 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 2,449E-03 0,0276653 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,449E-03 0,02753602 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 2,449E-03 0,02740794 ! transcription from RNA polymerase III promoter GO:0006383 41 20 1,000 2,449E-03 0,02728106 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 2,449E-03 0,02715534 GO:0010675|regulation of cellular carbohydrate metabolic process, ! DNA duplex unwinding GO:0032508 31 20 1,000 2,449E-03 0,02703077 GO:0032392|DNA geometric change, ! body fluid secretion GO:0007589 31 20 1,000 2,449E-03 0,02690734 ! negative regulation of translation GO:0017148 29 20 1,000 2,449E-03 0,02678504 ! organelle localization GO:0051640 136 74 2,000 2,612E-03 0,02843109 ! cell aging GO:0007569 44 21 1,000 2,7E-03 0,02926737 ! DNA modification GO:0006304 34 21 1,000 2,7E-03 0,02913613 ! positive regulation of locomotion GO:0040017 39 21 1,000 2,7E-03 0,02900605 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! cell-matrix adhesion GO:0007160 163 75 2,000 2,713E-03 0,02901185 ! regulation of chemotaxis GO:0050920 40 22 1,000 2,963E-03 0,0315484 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 2,963E-03 0,03140942 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 2,963E-03 0,03127166 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 2,963E-03 0,0311351 ! ureteric bud development GO:0001657 43 22 1,000 2,963E-03 0,03099973 ! renal system process GO:0003014 41 22 1,000 2,963E-03 0,03086553 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 2,963E-03 0,03073249 ! protein stabilization GO:0050821 39 22 1,000 2,963E-03 0,03060059 ! blood coagulation GO:0007596 146 78 2,000 3,032E-03 0,03117859 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 2,000 3,032E-03 0,03104591 ! sex determination GO:0007530 47 23 1,000 3,238E-03 0,0330095 ! muscle cell differentiation GO:0042692 159 80 2,000 3,257E-03 0,03306932 ! cell-substrate adhesion GO:0031589 171 81 2,000 3,374E-03 0,03410606 ! response to nutrient GO:0007584 125 82 2,000 3,493E-03 0,03515945 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 3,493E-03 0,03501296 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 3,524E-03 0,03517867 ! regulation of behavior GO:0050795 43 24 1,000 3,524E-03 0,0350333 ! lymphocyte proliferation GO:0046651 48 24 1,000 3,524E-03 0,03488913 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 3,524E-03 0,03474614 ! protein tetramerization GO:0051262 52 24 1,000 3,524E-03 0,03460432 ! hemostasis GO:0007599 158 84 2,000 3,738E-03 0,03655757 ! vasculogenesis GO:0001570 46 25 1,000 3,821E-03 0,03721936 ! somitogenesis GO:0001756 43 25 1,000 3,821E-03 0,03706928 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 4,129E-03 0,03990122 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 4,129E-03 0,03974161 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 4,129E-03 0,03958328 ! cellular response to oxidative stress GO:0034599 39 26 1,000 4,129E-03 0,0394262 ! leukocyte proliferation GO:0070661 52 26 1,000 4,129E-03 0,03927037 GO:0032943|mononuclear cell proliferation, ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 4,449E-03 0,04214377 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 4,449E-03 0,0419785 ! protein amino acid acylation GO:0043543 55 27 1,000 4,449E-03 0,04181452 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 4,449E-03 0,04165182 ! regulation of cell cycle process GO:0010564 149 90 2,000 4,536E-03 0,04229718 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 4,78E-03 0,04440278 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 4,78E-03 0,044232 ! leukocyte differentiation GO:0002521 202 96 2,000 5,429E-03 0,0500472 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 5,587E-03 0,051311 ! triglyceride metabolic process GO:0006641 43 31 1,000 5,838E-03 0,05340618 ! metanephros development GO:0001656 74 32 1,000 6,212E-03 0,05661498 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 6,212E-03 0,05640134 ! positive regulation of catabolic process GO:0009896 64 32 1,000 6,212E-03 0,05618931 ! positive regulation of endocytosis GO:0045807 50 34 1,000 6,993E-03 0,06301222 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 6,993E-03 0,0627771 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 7,399E-03 0,06617563 ! neutral lipid metabolic process GO:0006638 50 35 1,000 7,399E-03 0,06593053 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 7,399E-03 0,06568725 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 7,815E-03 0,06912984 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! tissue remodeling GO:0048771 76 37 1,000 8,242E-03 0,0726384 ! glycerol ether metabolic process GO:0006662 53 37 1,000 8,242E-03 0,0723733 ! regulation of protein stability GO:0031647 73 37 1,000 8,242E-03 0,07211012 ! organic ether metabolic process GO:0018904 55 39 1,000 9,126E-03 0,07955846 ! segmentation GO:0035282 67 39 1,000 9,126E-03 0,07927124 ! Rho protein signal transduction GO:0007266 74 39 1,000 9,126E-03 0,07898609 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,01005123 0,08667834 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,0105286 0,09047078 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,0105286 0,09014882 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,0105286 0,08982915 ! neuron migration GO:0001764 79 42 1,000 0,0105286 0,08951173 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,0105286 0,08919655 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,01101585 0,09299695 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,01101585 0,09267179 ! biopolymer methylation GO:0043414 84 44 1,000 0,01151289 0,0965157 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,01151289 0,09618058 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,01253603 0,10436573 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,01253603 0,10400585 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,01253603 0,10364844 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,01253603 0,10329348 ! pigmentation GO:0043473 100 46 1,000 0,01253603 0,10294094 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01253603 0,1025908 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01306199 0,10653269 ! response to calcium ion GO:0051592 81 47 1,000 0,01306199 0,10617278 ! methylation GO:0032259 90 47 1,000 0,01306199 0,1058153 ! protein homooligomerization GO:0051260 76 47 1,000 0,01306199 0,10546021 ! histone modification GO:0016570 91 50 1,000 0,01469646 0,11825984 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01469646 0,11786564 ! positive regulation of binding GO:0051099 78 51 1,000 0,01525991 0,12197788 ! excretion GO:0007588 83 51 1,000 0,01525991 0,12157398 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,01525991 0,12117275 ! membrane fusion GO:0006944 110 52 1,000 0,01583254 0,12530622 ! positive regulation of growth GO:0045927 90 52 1,000 0,01583254 0,12489538 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01583254 0,12448723 ! amino acid activation GO:0043038 92 52 1,000 0,01583254 0,12408173 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! regulation of translational initiation GO:0006446 82 53 1,000 0,01641428 0,12822325 ! cell maturation GO:0048469 100 53 1,000 0,01641428 0,12780829 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01641428 0,12739601 ! heart morphogenesis GO:0003007 97 55 1,000 0,0176048 0,13619666 ! nuclear export GO:0051168 97 55 1,000 0,0176048 0,13576013 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,0176048 0,13532639 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,018294 0,1401763 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,018294 0,1397313 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,018294 0,13928911 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,018294 0,13884971 ! neuron fate determination GO:0048664 7 5 0,000 0,018294 0,13841308 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,018294 0,13797918 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,018294 0,13754799 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,018294 0,1371195 ! polyol transport GO:0015791 12 5 0,000 0,018294 0,13669366 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,018294 0,13627046 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,018294 0,13584987 ! response to superoxide GO:0000303 10 5 0,000 0,018294 0,13543187 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,018294 0,13501644 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,018294 0,13460354 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,018294 0,13419317 ! female meiosis GO:0007143 7 5 0,000 0,018294 0,13378528 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,018294 0,13337987 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,018294 0,13297691 ! cobalt ion transport GO:0006824 11 5 0,000 0,018294 0,13257638 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,018294 0,13217825 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,018294 0,13178251 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,018294 0,13138913 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,018294 0,13099809 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,018294 0,13060937 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,018294 0,13022295 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,018294 0,12983881 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,018294 0,12945694 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,018294 0,1290773 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,018294 0,12869988 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,018294 0,12832466 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,018294 0,12795162 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,018294 0,12758075 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,018294 0,12721202 ! negative chemotaxis GO:0050919 14 5 0,000 0,018294 0,12684541 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,018294 0,12648091 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,018294 0,1261185 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,018294 0,12575817 ! behavioral response to pain GO:0048266 9 5 0,000 0,018294 0,12539988 ! clathrin coat assembly GO:0048268 14 5 0,000 0,018294 0,12504363 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,018294 0,1246894 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,018294 0,12433717 ! micturition GO:0060073 9 5 0,000 0,018294 0,12398692 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,018294 0,12363865 ! copulation GO:0007620 9 5 0,000 0,018294 0,12329232 ! glial cell fate commitment GO:0021781 13 5 0,000 0,018294 0,12294793 ! spermidine metabolic process GO:0008216 7 5 0,000 0,018294 0,12260545 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,018294 0,12226488 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,018294 0,1219262 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,018294 0,12158939 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,018294 0,12125443 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,018294 0,12092131 ! grooming behavior GO:0007625 6 5 0,000 0,018294 0,12059002 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,018294 0,12026054 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,018294 0,11993286 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,018294 0,11960695 ! response to protozoan GO:0001562 10 5 0,000 0,018294 0,11928281 ! lymph vessel development GO:0001945 10 5 0,000 0,018294 0,11896043 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,018294 0,11863978 ! endochondral ossification GO:0001958 16 5 0,000 0,018294 0,11832086 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,018294 0,11800364 ! parathyroid gland development GO:0060017 13 5 0,000 0,018294 0,11768812 ! anagen GO:0042640 6 5 0,000 0,018294 0,11737429 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,018294 0,11706212 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,018294 0,11675161 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,018294 0,11644275 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,018294 0,11613551 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,018294 0,11582989 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,018294 0,11552587 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,018294 0,11522345 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,018294 0,11492261 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,018294 0,11462333 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,018294 0,11432561 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,018294 0,11402943 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,018294 0,11373478 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,018294 0,11344164 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,018294 0,11315002 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,018294 0,11285989 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,018294 0,11257125 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,018294 0,11228408 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,018294 0,11199837 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,018294 0,11171411 ! histidine catabolic process GO:0006548 6 5 0,000 0,018294 0,11143129 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,018294 0,11114989 ! microvillus organization GO:0032528 7 5 0,000 0,018294 0,11086992 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,018294 0,11059135 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,018294 0,11031418 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,018294 0,1100384 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,018294 0,10976399 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,018294 0,10949094 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,018294 0,10921925 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,018294 0,10894891 ! polyol catabolic process GO:0046174 7 5 0,000 0,018294 0,1086799 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,018294 0,10841221 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,018294 0,10814584 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,018294 0,10788078 ! muscle cell migration GO:0014812 8 5 0,000 0,018294 0,10761701 ! mitochondrial fission GO:0000266 8 5 0,000 0,018294 0,10735453 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,018294 0,10709333 ! mRNA transcription GO:0009299 9 5 0,000 0,018294 0,10683339 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,018294 0,10657472 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,018294 0,10631729 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,018294 0,1060611 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,018294 0,10580615 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,018294 0,10555242 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,018294 0,1052999 ! response to food GO:0032094 6 5 0,000 0,018294 0,10504859 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,018294 0,10479847 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,018294 0,10454954 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,018294 0,1043018 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,018294 0,10405522 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,018294 0,10380981 ! forebrain neuron development GO:0021884 13 5 0,000 0,018294 0,10356555 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,018294 0,10332244 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,018294 0,10308046 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,018294 0,10283962 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,018294 0,1025999 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,018294 0,1023613 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,018294 0,1021238 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,018294 0,1018874 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,018294 0,1016521 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,018294 0,10141788 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,018294 0,10118473 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,018294 0,10095266 ! basic amino acid transport GO:0015802 11 5 0,000 0,018294 0,10072164 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,018294 0,10049169 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,018294 0,10026277 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,018294 0,1000349 ! depyrimidination GO:0045008 10 5 0,000 0,018294 0,09980807 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,018294 0,09958226 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,018294 0,09935747 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,018294 0,09913369 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,018294 0,09891092 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,018294 0,09868914 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,018294 0,09846836 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,018294 0,09824857 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,018294 0,09802975 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,018294 0,09781191 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,018294 0,09759503 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,018294 0,09737911 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,018294 0,09716415 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,018294 0,09695013 ! response to arsenic GO:0046685 10 5 0,000 0,018294 0,09673705 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,018294 0,09652491 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,018294 0,09631369 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,018294 0,0961034 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,018294 0,09589403 ! response to cadmium ion GO:0046686 7 5 0,000 0,018294 0,09568556 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,018294 0,095478 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,018294 0,09527134 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,018294 0,09506557 ! decidualization GO:0046697 11 5 0,000 0,018294 0,09486069 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,018294 0,09465668 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,018294 0,09445356 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,018294 0,0942513 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,018294 0,09404991 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,018294 0,09384938 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,018294 0,0936497 ! neural tube patterning GO:0021532 7 5 0,000 0,018294 0,09345087 ! embryonic cleavage GO:0040016 6 5 0,000 0,018294 0,09325288 ! peroxisome fission GO:0016559 5 5 0,000 0,018294 0,09305573 ! histone demethylation GO:0016577 10 5 0,000 0,018294 0,09285941 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,018294 0,09266391 ! mitotic recombination GO:0006312 9 5 0,000 0,018294 0,09246924 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,018294 0,09227538 ! metaphase plate congression GO:0051310 7 5 0,000 0,018294 0,09208234 ! regulation of sterol transport GO:0032371 7 5 0,000 0,018294 0,0918901 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,018294 0,09169866 ! enteric nervous system development GO:0048484 8 5 0,000 0,018294 0,09150802 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,018294 0,09131817 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,018294 0,09112911 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,018294 0,09094082 ! muscle cell proliferation GO:0033002 11 5 0,000 0,018294 0,09075332 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,018294 0,09056658 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,018294 0,09038061 ! plasminogen activation GO:0031639 5 5 0,000 0,018294 0,09019541 ! B cell homeostasis GO:0001782 13 5 0,000 0,018294 0,09001096 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,018294 0,08982726 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,018294 0,08964431 ! metaphase GO:0051323 8 5 0,000 0,018294 0,08946211 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,018294 0,08928065 ! cellular response to nutrient GO:0031670 8 5 0,000 0,018294 0,08909992 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,018294 0,08891992 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,018294 0,08874064 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,018294 0,08856209 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,018294 0,08838425 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,018294 0,08820713 ! response to redox state GO:0051775 5 5 0,000 0,018294 0,08803072 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,018294 0,08785501 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,018294 0,08768 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,018294 0,08750568 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,018294 0,08733206 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,018294 0,08715913 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,018294 0,08698687 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,018294 0,0868153 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,018294 0,08664441 ! striatum development GO:0021756 9 5 0,000 0,018294 0,08647418 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,018294 0,08630462 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,018294 0,08613573 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,018294 0,0859675 ! glial cell migration GO:0008347 11 5 0,000 0,018294 0,08579992 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,018294 0,08563299 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,018294 0,08546671 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,018294 0,08530108 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,018294 0,08513609 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,018294 0,08497173 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,018294 0,08480801 ! neuroprotection GO:0043526 6 5 0,000 0,018294 0,08464492 ! neural plate development GO:0001840 8 5 0,000 0,018294 0,08448245 ! regulation of sensory perception GO:0051931 7 5 0,000 0,018294 0,08432061 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,018294 0,08415938 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,018294 0,08399878 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,018294 0,08383878 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,018294 0,08367939 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,018294 0,0835206 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,018294 0,08336242 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,018294 0,08320484 ! spindle assembly GO:0051225 6 5 0,000 0,018294 0,08304785 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,018294 0,08289145 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,018294 0,08273564 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,018294 0,08258041 ! drug metabolic process GO:0017144 6 5 0,000 0,018294 0,08242576 ! stem cell division GO:0017145 11 5 0,000 0,018294 0,0822717 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,018294 0,08211821 ! organ regeneration GO:0031100 7 5 0,000 0,018294 0,08196529 ! carnitine metabolic process GO:0009437 7 5 0,000 0,018294 0,08181293 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,018294 0,08166115 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,018294 0,08150992 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01883089 0,08374701 ! lipid modification GO:0030258 97 57 1,000 0,01883089 0,0835925 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,01883089 0,08343855 ! maintenance of location GO:0051235 118 57 1,000 0,01883089 0,08328517 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,0194571 0,08589683 ! regulation of endocytosis GO:0030100 91 58 1,000 0,0194571 0,08573951 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,02009197 0,0883753 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,02073545 0,09103924 ! kidney development GO:0001822 122 60 1,000 0,02073545 0,09087341 ! mesoderm development GO:0007498 119 61 1,000 0,02138747 0,09356045 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0219128 0,09568457 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0219128 0,09551122 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0219128 0,09533851 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0219128 0,09516642 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0219128 0,09499495 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0219128 0,09482409 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0219128 0,09465385 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0219128 0,09448422 ! sleep GO:0030431 13 6 0,000 0,0219128 0,0943152 ! response to oxygen radical GO:0000305 11 6 0,000 0,0219128 0,09414678 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0219128 0,09397896 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0219128 0,09381174 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0219128 0,09364511 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0219128 0,09347907 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0219128 0,09331362 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0219128 0,09314876 ! forebrain regionalization GO:0021871 8 6 0,000 0,0219128 0,09298447 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0219128 0,09282077 ! male meiosis GO:0007140 7 6 0,000 0,0219128 0,09265764 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0219128 0,09249508 ! response to zinc ion GO:0010043 9 6 0,000 0,0219128 0,09233309 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0219128 0,09217167 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,0219128 0,09201081 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0219128 0,09185052 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0219128 0,09169078 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0219128 0,09153159 ! malate metabolic process GO:0006108 11 6 0,000 0,0219128 0,09137296 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0219128 0,09121487 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0219128 0,09105733 ! protein refolding GO:0042026 15 6 0,000 0,0219128 0,09090034 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0219128 0,09074388 ! opsonization GO:0008228 8 6 0,000 0,0219128 0,09058797 ! mating behavior GO:0007617 7 6 0,000 0,0219128 0,09043258 ! neuron remodeling GO:0016322 15 6 0,000 0,0219128 0,09027773 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0219128 0,09012341 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,0219128 0,08996962 ! equilibrioception GO:0050957 14 6 0,000 0,0219128 0,08981635 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0219128 0,0896636 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0219128 0,08951137 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0219128 0,08935965 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0219128 0,08920845 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0219128 0,08905776 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0219128 0,08890758 ! toxin metabolic process GO:0009404 11 6 0,000 0,0219128 0,08875791 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0219128 0,08860873 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0219128 0,08846006 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0219128 0,08831189 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0219128 0,08816421 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0219128 0,08801702 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0219128 0,08787033 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0219128 0,08772412 ! thymic T cell selection GO:0045061 12 6 0,000 0,0219128 0,0875784 ! protein lipoylation GO:0009249 10 6 0,000 0,0219128 0,08743316 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0219128 0,0872884 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0219128 0,08714413 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0219128 0,08700032 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0219128 0,08685699 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0219128 0,08671414 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0219128 0,08657175 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,0219128 0,08642983 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0219128 0,08628837 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0219128 0,08614738 ! hyperosmotic response GO:0006972 9 6 0,000 0,0219128 0,08600684 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0219128 0,08586677 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0219128 0,08572715 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0219128 0,08558798 ! urea metabolic process GO:0019627 7 6 0,000 0,0219128 0,08544926 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0219128 0,085311 ! neutrophil activation GO:0042119 8 6 0,000 0,0219128 0,08517318 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0219128 0,0850358 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0219128 0,08489887 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0219128 0,08476237 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0219128 0,08462632 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0219128 0,0844907 ! neuron apoptosis GO:0051402 9 6 0,000 0,0219128 0,08435551 ! nucleoside salvage GO:0043174 9 6 0,000 0,0219128 0,08422076 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0219128 0,08408644 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0219128 0,08395254 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0219128 0,08381907 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0219128 0,08368603 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,0219128 0,0835534 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0219128 0,0834212 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0219128 0,08328941 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0219128 0,08315804 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0219128 0,08302708 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0219128 0,08289653 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0219128 0,0827664 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0219128 0,08263667 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0219128 0,08250735 ! establishment of spindle localization GO:0051293 12 6 0,000 0,0219128 0,08237843 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0219128 0,08224992 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0219128 0,0821218 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,0219128 0,08199408 ! neural nucleus development GO:0048857 14 6 0,000 0,0219128 0,08186676 ! response to UV-C GO:0010225 11 6 0,000 0,0219128 0,08173984 ! astrocyte development GO:0014002 15 6 0,000 0,0219128 0,08161331 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0219128 0,08148717 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0219128 0,08136141 ! interaction with symbiont GO:0051702 13 6 0,000 0,0219128 0,08123605 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0219128 0,08111107 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0219128 0,08098648 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0219128 0,08086226 ! response to copper ion GO:0046688 10 6 0,000 0,0219128 0,08073843 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0219128 0,08061498 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0219128 0,0804919 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0219128 0,0803692 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0219128 0,08024687 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0219128 0,08012492 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0219128 0,08000333 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0219128 0,07988211 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0219128 0,07976126 ! hair follicle maturation GO:0048820 7 6 0,000 0,0219128 0,07964078 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0219128 0,07952066 ! Schwann cell development GO:0014044 15 6 0,000 0,0219128 0,0794009 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0219128 0,0792815 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0219128 0,07916246 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,0219128 0,07904377 ! subpallium development GO:0021544 10 6 0,000 0,0219128 0,07892544 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0219128 0,07880747 ! histone ubiquitination GO:0016574 8 6 0,000 0,0219128 0,07868984 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0219128 0,07857257 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0219128 0,07845565 ! G2 phase GO:0051319 16 6 0,000 0,0219128 0,07833907 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0219128 0,07822284 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0219128 0,07810696 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0219128 0,07799141 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0219128 0,07787621 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0219128 0,07776135 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0219128 0,07764683 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0219128 0,07753264 ! receptor internalization GO:0031623 10 6 0,000 0,0219128 0,07741879 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0219128 0,07730527 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0219128 0,07719209 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0219128 0,07707923 ! protein deubiquitination GO:0016579 14 6 0,000 0,0219128 0,07696671 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,0219128 0,07685451 ! protein destabilization GO:0031648 9 6 0,000 0,0219128 0,07674264 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0219128 0,0766311 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0219128 0,07651988 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0219128 0,07640898 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0219128 0,0762984 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0219128 0,07618814 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0219128 0,0760782 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0219128 0,07596858 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0219128 0,07585927 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0219128 0,07575028 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0219128 0,0756416 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0219128 0,07553323 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0219128 0,07542517 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0219128 0,07531742 ! catecholamine transport GO:0051937 9 6 0,000 0,0219128 0,07520998 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0219128 0,07510284 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0219128 0,07499601 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0219128 0,07488948 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0219128 0,07478326 ! maternal placenta development GO:0001893 12 6 0,000 0,0219128 0,07467733 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0219128 0,07457171 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0219128 0,07446638 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,0219128 0,07436135 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0219128 0,07425661 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0219128 0,07415217 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0219128 0,07404803 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0219128 0,07394417 ! regulation of mitosis GO:0007088 105 63 1,000 0,02271682 0,07654994 GO:0051783|regulation of nuclear division, ! germ cell development GO:0007281 118 65 1,000 0,02407946 0,08102821 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,02477309 0,08324588 ! developmental maturation GO:0021700 116 66 1,000 0,02477309 0,08312978 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,02547484 0,08536554 ! chromosome segregation GO:0007059 113 67 1,000 0,02547484 0,08524682 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,02547484 0,08512842 ! adaptive immune response GO:0002250 119 67 1,000 0,02547484 0,08501035 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! tRNA transcription GO:0009304 14 7 0,000 0,02551838 0,08503771 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02551838 0,08492009 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02551838 0,0848028 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02551838 0,08468583 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02551838 0,08456918 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02551838 0,08445286 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02551838 0,08433685 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02551838 0,08422116 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02551838 0,08410579 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02551838 0,08399073 ! prostate gland development GO:0030850 13 7 0,000 0,02551838 0,08387599 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02551838 0,08376156 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02551838 0,08364745 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02551838 0,08353364 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02551838 0,08342014 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02551838 0,08330696 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02551838 0,08319407 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02551838 0,0830815 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02551838 0,08296922 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02551838 0,08285726 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02551838 0,08274559 ! glycolipid transport GO:0046836 10 7 0,000 0,02551838 0,08263422 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02551838 0,08252315 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02551838 0,08241238 ! neuron adhesion GO:0007158 12 7 0,000 0,02551838 0,08230191 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02551838 0,08219174 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02551838 0,08208185 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02551838 0,08197226 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02551838 0,08186297 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02551838 0,08175396 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02551838 0,08164525 ! pericardium development GO:0060039 14 7 0,000 0,02551838 0,08153682 ! fibril organization GO:0043206 16 7 0,000 0,02551838 0,08142868 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02551838 0,08132083 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02551838 0,08121326 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02551838 0,08110598 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02551838 0,08099898 ! lipoprotein transport GO:0042953 14 7 0,000 0,02551838 0,08089226 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02551838 0,08078582 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02551838 0,08067967 ! rhythmic behavior GO:0007622 15 7 0,000 0,02551838 0,08057379 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02551838 0,08046819 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02551838 0,08036286 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02551838 0,08025781 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02551838 0,08015304 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02551838 0,08004853 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02551838 0,0799443 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02551838 0,07984035 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02551838 0,07973666 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02551838 0,07963324 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02551838 0,07953009 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02551838 0,0794272 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02551838 0,07932458 ! spinal cord patterning GO:0021511 13 7 0,000 0,02551838 0,07922223 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02551838 0,07912014 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02551838 0,07901831 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02551838 0,07891674 ! adrenal gland development GO:0030325 17 7 0,000 0,02551838 0,07881544 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02551838 0,07871439 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02551838 0,07861361 ! ovulation GO:0030728 9 7 0,000 0,02551838 0,07851308 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02551838 0,0784128 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02551838 0,07831279 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02551838 0,07821303 ! microtubule nucleation GO:0007020 20 7 0,000 0,02551838 0,07811352 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02551838 0,07801426 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02551838 0,07791526 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02551838 0,07781651 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02551838 0,07771801 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02551838 0,07761975 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02551838 0,07752175 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02551838 0,07742399 ! galactose metabolic process GO:0006012 13 7 0,000 0,02551838 0,07732648 ! vesicle fusion GO:0006906 17 7 0,000 0,02551838 0,07722922 ! response to dietary excess GO:0002021 8 7 0,000 0,02551838 0,07713219 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02551838 0,07703542 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02551838 0,07693888 GO:0045851|pH reduction, ! melanosome organization GO:0032438 9 7 0,000 0,02551838 0,07684259 ! organ growth GO:0035265 15 7 0,000 0,02551838 0,07674653 ! purine salvage GO:0043101 10 7 0,000 0,02551838 0,07665072 ! nucleoside transport GO:0015858 8 7 0,000 0,02551838 0,07655514 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02551838 0,07645981 ! parturition GO:0007567 14 7 0,000 0,02551838 0,07636471 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02551838 0,07626985 ! rRNA modification GO:0000154 14 7 0,000 0,02551838 0,07617522 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02551838 0,07608083 ! spindle checkpoint GO:0031577 15 7 0,000 0,02551838 0,07598667 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02551838 0,07589274 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02551838 0,07579904 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02551838 0,07570558 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02551838 0,07561235 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02551838 0,07551934 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02551838 0,07542657 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02551838 0,07533402 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02551838 0,0752417 ! fibrinolysis GO:0042730 10 7 0,000 0,02551838 0,0751496 ! eating behavior GO:0042755 7 7 0,000 0,02551838 0,07505773 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02551838 0,07496609 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02551838 0,07487467 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02551838 0,07478347 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02551838 0,07469249 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02551838 0,07460173 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02551838 0,0745112 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02551838 0,07442088 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02551838 0,07433078 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02551838 0,0742409 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02551838 0,07415124 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02551838 0,07406179 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02551838 0,07397256 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02551838 0,07388355 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02551838 0,07379474 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02551838 0,07370615 ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02551838 0,07361778 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02551838 0,07352961 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02551838 0,07344166 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02551838 0,07335391 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02551838 0,07326638 ! transcription termination GO:0006353 13 7 0,000 0,02551838 0,07317905 ! response to tumor cell GO:0002347 13 7 0,000 0,02551838 0,07309194 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02551838 0,07300503 ! anaphase GO:0051322 17 7 0,000 0,02551838 0,07291832 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02551838 0,07283182 ! axonal fasciculation GO:0007413 18 7 0,000 0,02551838 0,07274553 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02551838 0,07265944 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02551838 0,07257355 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02551838 0,07248787 ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02551838 0,07240239 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02551838 0,07231711 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02551838 0,07223203 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02551838 0,07214715 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02551838 0,07206247 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02551838 0,07197799 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02551838 0,07189371 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02551838 0,07180962 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02551838 0,07172573 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02551838 0,07164204 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02551838 0,07155854 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02551838 0,07147523 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02551838 0,07139212 ! lymph node development GO:0048535 10 7 0,000 0,02551838 0,07130921 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02551838 0,07122648 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02551838 0,07114395 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02551838 0,0710616 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02551838 0,07097945 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02551838 0,07089749 ! adult feeding behavior GO:0008343 9 7 0,000 0,02551838 0,07081572 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02551838 0,07073413 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02551838 0,07065273 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02551838 0,07057152 ! muscle adaptation GO:0043500 14 7 0,000 0,02551838 0,0704905 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02551838 0,07040966 ! retina homeostasis GO:0001895 12 7 0,000 0,02551838 0,07032901 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02551838 0,07024854 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02551838 0,07016826 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02551838 0,07008816 ! protein prenylation GO:0018342 18 7 0,000 0,02551838 0,07000824 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02551838 0,0699285 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02551838 0,06984895 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02551838 0,06976958 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,02690241 0,07347016 ! negative regulation of cell size GO:0045792 134 69 1,000 0,02690241 0,07338686 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,02690241 0,07330375 ! urogenital system development GO:0001655 137 69 1,000 0,02690241 0,07322083 ! antigen processing and presentation GO:0019882 104 69 1,000 0,02690241 0,07313809 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02910296 0,0790313 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02911079 0,07896343 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02911079 0,07887451 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02911079 0,07878579 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02911079 0,07869726 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02911079 0,07860894 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02911079 0,07852081 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02911079 0,07843288 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02911079 0,07834515 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02911079 0,07825761 ! meiotic prophase I GO:0007128 13 8 0,000 0,02911079 0,07817027 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02911079 0,07808313 ! oligopeptide transport GO:0006857 15 8 0,000 0,02911079 0,07799617 ! UTP metabolic process GO:0046051 8 8 0,000 0,02911079 0,07790942 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02911079 0,07782285 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02911079 0,07773648 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02911079 0,07765029 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02911079 0,0775643 ! succinate metabolic process GO:0006105 14 8 0,000 0,02911079 0,0774785 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02911079 0,07739289 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02911079 0,07730747 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02911079 0,07722223 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02911079 0,07713719 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02911079 0,07705233 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02911079 0,07696765 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02911079 0,07688317 ! reflex GO:0060004 16 8 0,000 0,02911079 0,07679886 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02911079 0,07671475 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02911079 0,07663081 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02911079 0,07654706 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02911079 0,0764635 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02911079 0,07638011 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02911079 0,07629691 ! pigment granule organization GO:0048753 16 8 0,000 0,02911079 0,07621389 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02911079 0,07613105 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02911079 0,07604839 ! histidine metabolic process GO:0006547 16 8 0,000 0,02911079 0,0759659 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02911079 0,0758836 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02911079 0,07580148 ! glycine catabolic process GO:0006546 13 8 0,000 0,02911079 0,07571953 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02911079 0,07563776 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02911079 0,07555616 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,02911079 0,07547475 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02911079 0,0753935 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02911079 0,07531243 ! melanin metabolic process GO:0006582 15 8 0,000 0,02911079 0,07523154 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02911079 0,07515082 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02911079 0,07507027 ! macrophage activation GO:0042116 12 8 0,000 0,02911079 0,0749899 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02911079 0,07490969 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02911079 0,07482966 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02911079 0,0747498 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02911079 0,07467011 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02911079 0,07459059 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02911079 0,07451124 ! osteoblast development GO:0002076 16 8 0,000 0,02911079 0,07443206 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02911079 0,07435304 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02911079 0,07427419 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02911079 0,07419551 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02911079 0,074117 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02911079 0,07403865 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02911079 0,07396047 ! response to UV-B GO:0010224 16 8 0,000 0,02911079 0,07388245 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02911079 0,0738046 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02911079 0,07372691 ! intermediate filament organization GO:0045109 12 8 0,000 0,02911079 0,07364938 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02911079 0,07357202 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02911079 0,07349482 ! cellular extravasation GO:0045123 12 8 0,000 0,02911079 0,07341778 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02911079 0,0733409 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02911079 0,07326419 ! response to antibiotic GO:0046677 11 8 0,000 0,02911079 0,07318763 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02911079 0,07311124 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02911079 0,073035 ! DNA topological change GO:0006265 12 8 0,000 0,02911079 0,07295892 ! response to tropane GO:0014073 15 8 0,000 0,02911079 0,072883 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02911079 0,07280724 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02911079 0,07273163 ! melanosome transport GO:0032402 13 8 0,000 0,02911079 0,07265619 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02911079 0,0725809 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02911079 0,07250576 ! mast cell activation GO:0045576 14 8 0,000 0,02911079 0,07243078 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02911079 0,07235595 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02911079 0,07228128 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02911079 0,07220677 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02911079 0,0721324 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02911079 0,07205819 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02911079 0,07198414 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02911079 0,07191023 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02911079 0,07183648 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02911079 0,07176287 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02911079 0,07168942 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02911079 0,07161612 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02911079 0,07154297 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02911079 0,07146996 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02911079 0,07139711 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02911079 0,0713244 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02911079 0,07125185 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02911079 0,07117944 ! hormone catabolic process GO:0042447 17 8 0,000 0,02911079 0,07110717 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02911079 0,07103505 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02911079 0,07096308 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02911079 0,07089126 ! ATP catabolic process GO:0006200 11 8 0,000 0,02911079 0,07081958 ! blastocyst growth GO:0001832 19 8 0,000 0,02911079 0,07074804 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02911079 0,07067665 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02911079 0,07060541 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02911079 0,0705343 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02911079 0,07046334 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02911079 0,07039253 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02911079 0,07032185 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02911079 0,07025132 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02911079 0,07018093 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02911079 0,07011067 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02911079 0,07004056 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02911079 0,06997059 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02911079 0,06990076 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02911079 0,06983107 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02911079 0,06976152 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02911079 0,0696921 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02911079 0,06962283 ! axon guidance GO:0007411 139 73 1,000 0,029852 0,07132463 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,03060868 0,07306 GO:0090046|regulation of transcription regulator activity, ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,03137294 0,07481 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,03137294 0,07473593 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,03137294 0,07466201 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,03214472 0,07642312 ! regulation of catabolic process GO:0009894 161 76 1,000 0,03214472 0,07634768 ! axon extension GO:0048675 15 9 0,000 0,03269008 0,0775664 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03269008 0,07748997 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03269008 0,07741371 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03269008 0,07733759 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03269008 0,07726162 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03269008 0,07718579 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03269008 0,07711012 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03269008 0,0770346 ! phosphate transport GO:0006817 19 9 0,000 0,03269008 0,07695922 ! reproductive behavior GO:0019098 19 9 0,000 0,03269008 0,07688399 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03269008 0,07680891 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03269008 0,07673398 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03269008 0,07665919 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03269008 0,07658454 ! GTP metabolic process GO:0046039 9 9 0,000 0,03269008 0,07651004 ! RNA methylation GO:0001510 15 9 0,000 0,03269008 0,07643569 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03269008 0,07636148 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03269008 0,07628741 ! artery development GO:0060840 24 9 0,000 0,03269008 0,07621349 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03269008 0,07613971 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03269008 0,07606608 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03269008 0,07599258 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03269008 0,07591923 ! chemosensory behavior GO:0007635 20 9 0,000 0,03269008 0,07584602 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03269008 0,07577295 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03269008 0,07570002 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03269008 0,07562724 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03269008 0,07555459 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03269008 0,07548208 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03269008 0,07540971 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03269008 0,07533748 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03269008 0,07526538 ! protein targeting to ER GO:0045047 22 9 0,000 0,03269008 0,07519343 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03269008 0,07512161 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03269008 0,07504993 ! T cell selection GO:0045058 23 9 0,000 0,03269008 0,07497838 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03269008 0,07490698 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03269008 0,0748357 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03269008 0,07476457 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03269008 0,07469357 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03269008 0,0746227 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03269008 0,07455197 ! mannose metabolic process GO:0006013 13 9 0,000 0,03269008 0,07448137 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03269008 0,0744109 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03269008 0,07434057 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03269008 0,07427037 ! receptor clustering GO:0043113 18 9 0,000 0,03269008 0,07420031 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03269008 0,07413037 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03269008 0,07406057 ! ruffle organization GO:0031529 15 9 0,000 0,03269008 0,0739909 ! retinol metabolic process GO:0042572 18 9 0,000 0,03269008 0,07392136 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03269008 0,07385195 ! behavioral fear response GO:0001662 22 9 0,000 0,03269008 0,07378267 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03269008 0,07371352 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03269008 0,0736445 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03269008 0,07357561 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,03269008 0,07350685 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03269008 0,07343821 ! segment specification GO:0007379 13 9 0,000 0,03269008 0,07336971 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03269008 0,07330133 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03269008 0,07323308 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03269008 0,07316495 ! response to amine stimulus GO:0014075 13 9 0,000 0,03269008 0,07309696 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03269008 0,07302909 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03269008 0,07296134 ! erythrocyte development GO:0048821 15 9 0,000 0,03269008 0,07289372 ! gas homeostasis GO:0033483 16 9 0,000 0,03269008 0,07282623 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03269008 0,07275886 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03269008 0,07269161 ! postreplication repair GO:0006301 22 9 0,000 0,03269008 0,07262449 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03269008 0,0725575 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03269008 0,07249062 ! icosanoid secretion GO:0032309 15 9 0,000 0,03269008 0,07242387 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03269008 0,07235724 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03269008 0,07229074 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03269008 0,07222436 ! regulation of cell division GO:0051302 15 9 0,000 0,03269008 0,0721581 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03269008 0,07209196 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03269008 0,07202594 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03269008 0,07196004 ! sterol catabolic process GO:0016127 11 9 0,000 0,03269008 0,07189426 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03269008 0,07182861 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03269008 0,07176307 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03269008 0,07169765 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03269008 0,07163235 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03269008 0,07156717 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03269008 0,07150211 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03269008 0,07143717 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03269008 0,07137235 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03269008 0,07130764 ! purine base metabolic process GO:0006144 21 9 0,000 0,03269008 0,07124305 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03269008 0,07117857 ! pigment granule transport GO:0051904 17 9 0,000 0,03269008 0,07111422 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03269008 0,07104998 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,03269008 0,07098585 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03269008 0,07092184 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03269008 0,07085795 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03269008 0,07079417 ! mitochondrion localization GO:0051646 15 9 0,000 0,03269008 0,07073051 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,03450452 0,07458929 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,03530573 0,07625277 ! response to metal ion GO:0010038 140 80 1,000 0,03530573 0,07618438 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,03530573 0,07611611 ! protein import into nucleus GO:0006606 158 80 1,000 0,03530573 0,07604797 ! T cell activation GO:0042110 168 81 1,000 0,03611413 0,07771968 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,03611413 0,07765023 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,03611413 0,0775809 ! nuclear import GO:0051170 161 81 1,000 0,03611413 0,07751169 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,03611413 0,07744261 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03625629 0,0776782 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03625629 0,07760909 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03625629 0,07754011 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03625629 0,07747125 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03625629 0,0774025 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03625629 0,07733388 ! synapsis GO:0007129 13 10 0,000 0,03625629 0,07726539 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03625629 0,07719701 ! N-glycan processing GO:0006491 20 10 0,000 0,03625629 0,07712876 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03625629 0,07706062 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03625629 0,07699261 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03625629 0,07692471 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03625629 0,07685694 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03625629 0,07678928 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03625629 0,07672174 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03625629 0,07665433 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03625629 0,07658703 ! androgen metabolic process GO:0008209 17 10 0,000 0,03625629 0,07651984 ! phospholipid efflux GO:0033700 16 10 0,000 0,03625629 0,07645278 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03625629 0,07638583 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03625629 0,076319 ! pathogenesis GO:0009405 13 10 0,000 0,03625629 0,07625229 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03625629 0,0761857 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03625629 0,07611922 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03625629 0,07605285 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03625629 0,0759866 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03625629 0,07592047 ! endoderm development GO:0007492 16 10 0,000 0,03625629 0,07585445 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03625629 0,07578855 ! arginine catabolic process GO:0006527 13 10 0,000 0,03625629 0,07572276 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03625629 0,07565709 ! proline metabolic process GO:0006560 13 10 0,000 0,03625629 0,07559153 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03625629 0,07552608 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03625629 0,07546075 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03625629 0,07539552 ! V(D)J recombination GO:0033151 28 10 0,000 0,03625629 0,07533042 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03625629 0,07526542 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03625629 0,07520054 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03625629 0,07513576 ! B cell proliferation GO:0042100 18 10 0,000 0,03625629 0,0750711 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03625629 0,07500655 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03625629 0,07494212 ! multicellular organism growth GO:0035264 18 10 0,000 0,03625629 0,07487779 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03625629 0,07481357 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03625629 0,07474946 ! epithelial cell development GO:0002064 20 10 0,000 0,03625629 0,07468546 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03625629 0,07462158 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03625629 0,0745578 ! macroautophagy GO:0016236 17 10 0,000 0,03625629 0,07449413 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03625629 0,07443056 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03625629 0,07436711 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03625629 0,07430377 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03625629 0,07424053 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,03625629 0,0741774 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03625629 0,07411438 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03625629 0,07405146 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03625629 0,07398865 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03625629 0,07392595 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03625629 0,07386335 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03625629 0,07380086 ! response to dsRNA GO:0043331 20 10 0,000 0,03625629 0,07373848 ! DNA ligation GO:0006266 19 10 0,000 0,03625629 0,0736762 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03625629 0,07361403 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03625629 0,07355196 ! melanosome localization GO:0032400 16 10 0,000 0,03625629 0,07348999 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03625629 0,07342813 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03625629 0,07336638 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03625629 0,07330472 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03625629 0,07324318 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03625629 0,07318173 ! mRNA cleavage GO:0006379 17 10 0,000 0,03625629 0,07312039 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03625629 0,07305915 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03625629 0,07299801 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03625629 0,07293697 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03625629 0,07287604 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03625629 0,07281521 ! salivary gland development GO:0007431 27 10 0,000 0,03625629 0,07275448 ! prophase GO:0051324 15 10 0,000 0,03625629 0,07269385 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03625629 0,07263332 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03625629 0,0725729 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03625629 0,07251257 ! midbrain development GO:0030901 13 10 0,000 0,03625629 0,07245234 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03625629 0,07239222 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03625629 0,07233219 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03625629 0,07227226 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03625629 0,07221244 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03625629 0,07215271 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03625629 0,07209308 ! detection of calcium ion GO:0005513 23 10 0,000 0,03625629 0,07203354 ! oocyte development GO:0048599 17 10 0,000 0,03625629 0,07197411 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03625629 0,07191477 ! blastocyst formation GO:0001825 17 10 0,000 0,03625629 0,07185554 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03625629 0,0717964 ! activation of innate immune response GO:0002218 12 10 0,000 0,03625629 0,07173735 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03625629 0,07167841 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03625629 0,07161956 ! response to nicotine GO:0035094 20 10 0,000 0,03625629 0,07156081 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03625629 0,07150215 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03625629 0,07144359 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,03692967 0,07271096 ! response to drug GO:0042493 143 82 1,000 0,03692967 0,0726515 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,03692967 0,07259215 ! regulation of lyase activity GO:0051339 160 83 1,000 0,03775228 0,07414857 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,0385819 0,0757162 ! negative regulation of growth GO:0045926 155 84 1,000 0,0385819 0,07565449 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,03941847 0,07723196 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03980946 0,07793456 ! respiratory burst GO:0045730 17 11 0,000 0,03980946 0,0778712 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03980946 0,07780794 ! neuron fate specification GO:0048665 17 11 0,000 0,03980946 0,07774478 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03980946 0,07768173 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03980946 0,07761878 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,03980946 0,07755593 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03980946 0,07749318 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03980946 0,07743053 ! response to pain GO:0048265 24 11 0,000 0,03980946 0,07736799 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03980946 0,07730554 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03980946 0,0772432 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,03980946 0,07718096 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03980946 0,07711882 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03980946 0,07705677 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03980946 0,07699483 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03980946 0,07693299 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03980946 0,07687124 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03980946 0,0768096 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03980946 0,07674805 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03980946 0,07668661 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03980946 0,07662526 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,03980946 0,076564 ! lipid digestion GO:0044241 18 11 0,000 0,03980946 0,07650285 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03980946 0,0764418 ! UV protection GO:0009650 19 11 0,000 0,03980946 0,07638084 ! adult heart development GO:0007512 14 11 0,000 0,03980946 0,07631998 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03980946 0,07625921 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03980946 0,07619854 ! temperature homeostasis GO:0001659 17 11 0,000 0,03980946 0,07613797 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03980946 0,0760775 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03980946 0,07601712 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03980946 0,07595684 ! regulation of organ growth GO:0046620 13 11 0,000 0,03980946 0,07589665 ! pigment granule localization GO:0051875 20 11 0,000 0,03980946 0,07583656 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03980946 0,07577656 ! vasoconstriction GO:0042310 18 11 0,000 0,03980946 0,07571666 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03980946 0,07565685 ! embryonic axis specification GO:0000578 18 11 0,000 0,03980946 0,07559713 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03980946 0,07553752 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03980946 0,07547799 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03980946 0,07541856 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03980946 0,07535922 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03980946 0,07529998 ! zymogen activation GO:0031638 15 11 0,000 0,03980946 0,07524082 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03980946 0,07518177 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03980946 0,0751228 ! nucleosome positioning GO:0016584 15 11 0,000 0,03980946 0,07506393 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03980946 0,07500514 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03980946 0,07494646 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03980946 0,07488786 ! acid secretion GO:0046717 18 11 0,000 0,03980946 0,07482935 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03980946 0,07477094 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03980946 0,07471261 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03980946 0,07465438 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03980946 0,07459624 ! oocyte differentiation GO:0009994 18 11 0,000 0,03980946 0,07453819 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03980946 0,07448023 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03980946 0,07442235 ! cholesterol efflux GO:0033344 19 11 0,000 0,03980946 0,07436457 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03980946 0,07430688 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03980946 0,07424928 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03980946 0,07419177 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 15 11 0,000 0,03980946 0,07413434 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03980946 0,07407701 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03980946 0,07401976 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03980946 0,0739626 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03980946 0,07390553 ! defense response to fungus GO:0050832 13 11 0,000 0,03980946 0,07384855 ! developmental induction GO:0031128 19 11 0,000 0,03980946 0,07379166 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03980946 0,07373485 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03980946 0,07367813 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03980946 0,0736215 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03980946 0,07356495 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03980946 0,0735085 ! response to inorganic substance GO:0010035 153 86 1,000 0,04026193 0,07428697 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,04111221 0,07579769 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,04111221 0,07573965 ! regulation of protein transport GO:0051223 154 87 1,000 0,04111221 0,0756817 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,04196926 0,07720033 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04334966 0,0796786 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04334966 0,07961777 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04334966 0,07955704 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,04334966 0,0794964 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04334966 0,07943586 ! cartilage condensation GO:0001502 20 12 0,000 0,04334966 0,07937541 ! mating GO:0007618 17 12 0,000 0,04334966 0,07931504 ! protein complex disassembly GO:0043241 27 12 0,000 0,04334966 0,07925477 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04334966 0,0791946 ! hippocampus development GO:0021766 26 12 0,000 0,04334966 0,07913451 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04334966 0,07907451 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04334966 0,07901461 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,04334966 0,07895479 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04334966 0,07889507 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04334966 0,07883544 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04334966 0,07877589 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04334966 0,07871644 ! drug transport GO:0015893 16 12 0,000 0,04334966 0,07865708 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04334966 0,0785978 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04334966 0,07853862 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04334966 0,07847952 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04334966 0,07842051 ! focal adhesion formation GO:0048041 35 12 0,000 0,04334966 0,07836159 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04334966 0,07830276 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04334966 0,07824402 ! forebrain cell migration GO:0021885 21 12 0,000 0,04334966 0,07818537 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04334966 0,0781268 ! fear response GO:0042596 26 12 0,000 0,04334966 0,07806833 ! monoamine transport GO:0015844 18 12 0,000 0,04334966 0,07800993 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04334966 0,07795163 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04334966 0,07789341 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04334966 0,07783529 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04334966 0,07777724 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04334966 0,07771929 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04334966 0,07766142 ! protein homotetramerization GO:0051289 21 12 0,000 0,04334966 0,07760363 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04334966 0,07754593 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04334966 0,07748832 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04334966 0,0774308 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04334966 0,07737335 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04334966 0,077316 ! cranial nerve development GO:0021545 20 12 0,000 0,04334966 0,07725873 ! fucose catabolic process GO:0019317 22 12 0,000 0,04334966 0,07720154 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04334966 0,07714444 ! histone methylation GO:0016571 26 12 0,000 0,04334966 0,07708742 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04334966 0,07703049 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04334966 0,07697364 ! gland morphogenesis GO:0022612 29 12 0,000 0,04334966 0,07691687 ! T cell homeostasis GO:0043029 25 12 0,000 0,04334966 0,07686019 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04334966 0,0768036 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04334966 0,07674708 ! spleen development GO:0048536 22 12 0,000 0,04334966 0,07669065 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04334966 0,0766343 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04334966 0,07657803 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04334966 0,07652185 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04334966 0,07646575 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04334966 0,07640973 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04334966 0,07635379 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04334966 0,07629794 ! response to cold GO:0009409 17 12 0,000 0,04334966 0,07624217 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04334966 0,07618647 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04334966 0,07613086 ! ossification GO:0001503 188 90 1,000 0,04370341 0,07669613 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,04370341 0,07664023 ! bone development GO:0060348 189 91 1,000 0,04458039 0,0781212 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,04635386 0,08116986 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,04635386 0,08111083 ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04687692 0,08196648 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04687692 0,08190695 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04687692 0,08184751 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04687692 0,08178816 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04687692 0,08172889 ! lipid localization GO:0010876 28 13 0,000 0,04687692 0,08166971 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04687692 0,08161062 ! organelle fusion GO:0048284 32 13 0,000 0,04687692 0,08155161 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04687692 0,08149268 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04687692 0,08143384 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04687692 0,08137509 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04687692 0,08131642 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04687692 0,08125783 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04687692 0,08119933 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04687692 0,08114092 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04687692 0,08108258 ! methionine metabolic process GO:0006555 27 13 0,000 0,04687692 0,08102433 ! plasma membrane organization GO:0007009 24 13 0,000 0,04687692 0,08096617 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04687692 0,08090809 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04687692 0,08085009 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04687692 0,08079217 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04687692 0,08073434 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04687692 0,08067659 ! response to X-ray GO:0010165 25 13 0,000 0,04687692 0,08061892 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04687692 0,08056134 ! exocrine system development GO:0035272 32 13 0,000 0,04687692 0,08050383 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04687692 0,08044641 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04687692 0,08038907 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04687692 0,08033182 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04687692 0,08027464 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04687692 0,08021755 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04687692 0,08016053 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04687692 0,0801036 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04687692 0,08004675 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04687692 0,07998998 ! regulation of cellular pH GO:0030641 22 13 0,000 0,04687692 0,07993329 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04687692 0,07987668 ! ribosome assembly GO:0042255 17 13 0,000 0,04687692 0,07982015 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04687692 0,0797637 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04687692 0,07970733 ! chromatin silencing GO:0006342 26 13 0,000 0,04687692 0,07965104 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04687692 0,07959483 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04687692 0,0795387 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04687692 0,07948264 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04687692 0,07942667 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04687692 0,07937078 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04687692 0,07931496 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04687692 0,07925922 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04687692 0,07920356 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04687692 0,07914798 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04687692 0,07909248 ! embryonic placenta development GO:0001892 23 13 0,000 0,04687692 0,07903705 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04687692 0,0789817 ! insulin secretion GO:0030073 23 13 0,000 0,04687692 0,07892643 ! actin filament polymerization GO:0030041 24 13 0,000 0,04687692 0,07887124 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04687692 0,07881612 ! acrosome reaction GO:0007340 18 13 0,000 0,04687692 0,07876108 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,04815297 0,0808486 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,04815297 0,08079222 ! mRNA transport GO:0051028 169 96 1,000 0,04906199 0,08226003 ! regulation of protein localization GO:0032880 176 97 1,000 0,04997724 0,08373624 ! rRNA transcription GO:0009303 25 14 0,000 0,05039129 0,08437123 ! lactation GO:0007595 26 14 0,000 0,05039129 0,08431255 ! reproductive cellular process GO:0048610 20 14 0,000 0,05039129 0,08425396 ! tRNA modification GO:0006400 20 14 0,000 0,05039129 0,08419545 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05039129 0,08413702 ! regulation of S phase GO:0033261 23 14 0,000 0,05039129 0,08407868 ! water transport GO:0006833 21 14 0,000 0,05039129 0,08402041 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05039129 0,08396222 ! non-recombinational repair GO:0000726 25 14 0,000 0,05039129 0,08390412 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05039129 0,08384609 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05039129 0,08378815 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05039129 0,08373028 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,05039129 0,0836725 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05039129 0,08361479 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05039129 0,08355717 ! palate development GO:0060021 31 14 0,000 0,05039129 0,08349962 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,05039129 0,08344216 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05039129 0,08338477 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,05039129 0,08332746 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05039129 0,08327023 ! arginine metabolic process GO:0006525 17 14 0,000 0,05039129 0,08321308 ! regulation of heart rate GO:0002027 24 14 0,000 0,05039129 0,083156 ! organic alcohol transport GO:0015850 29 14 0,000 0,05039129 0,08309901 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05039129 0,08304209 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,05039129 0,08298525 ! embryo implantation GO:0007566 30 14 0,000 0,05039129 0,08292849 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05039129 0,08287181 ! L-amino acid transport GO:0015807 30 14 0,000 0,05039129 0,0828152 ! bone mineralization GO:0030282 17 14 0,000 0,05039129 0,08275867 ! stem cell development GO:0048864 43 14 0,000 0,05039129 0,08270222 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05039129 0,08264584 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,05039129 0,08258954 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05039129 0,08253332 ! cerebellum development GO:0021549 21 14 0,000 0,05039129 0,08247718 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05039129 0,08242111 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05039129 0,08236512 ! response to gamma radiation GO:0010332 28 14 0,000 0,05039129 0,0823092 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05039129 0,08225336 ! cofactor transport GO:0051181 26 14 0,000 0,05039129 0,08219759 ! NADP metabolic process GO:0006739 24 14 0,000 0,05039129 0,0821419 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05039129 0,08208629 ! intestinal absorption GO:0050892 25 14 0,000 0,05039129 0,08203075 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05039129 0,08197529 ! oxygen transport GO:0015671 21 14 0,000 0,05039129 0,0819199 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05039129 0,08186459 ! male genitalia development GO:0030539 24 14 0,000 0,05039129 0,08180935 ! regulation of axon extension GO:0030516 37 14 0,000 0,05039129 0,08175418 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,05039129 0,08169909 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05039129 0,08164408 ! response to virus GO:0009615 160 98 1,000 0,05089867 0,08241063 ! interphase GO:0051325 213 98 1,000 0,05089867 0,08235521 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,05182622 0,08379965 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05389282 0,0870827 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05389282 0,08702425 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,05389282 0,08696588 ! superoxide anion generation GO:0042554 20 15 0,000 0,05389282 0,0869076 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05389282 0,08684939 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05389282 0,08679125 ! copper ion transport GO:0006825 20 15 0,000 0,05389282 0,0867332 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05389282 0,08667522 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05389282 0,08661732 ! sulfate transport GO:0008272 23 15 0,000 0,05389282 0,0865595 ! response to cAMP GO:0051591 22 15 0,000 0,05389282 0,08650176 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05389282 0,08644409 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05389282 0,0863865 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05389282 0,08632898 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05389282 0,08627155 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05389282 0,08621418 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05389282 0,0861569 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05389282 0,08609969 ! pituitary gland development GO:0021983 29 15 0,000 0,05389282 0,08604256 ! vesicle coating GO:0006901 33 15 0,000 0,05389282 0,0859855 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05389282 0,08592852 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05389282 0,08587161 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,05389282 0,08581478 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05389282 0,08575802 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,05389282 0,08570134 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05389282 0,08564474 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05389282 0,08558821 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05389282 0,08553175 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05389282 0,08547537 ! histone deacetylation GO:0016575 20 15 0,000 0,05389282 0,08541906 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05389282 0,08536283 ! tissue regeneration GO:0042246 26 15 0,000 0,05389282 0,08530667 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05389282 0,08525058 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05389282 0,08519457 ! muscle maintenance GO:0046716 26 15 0,000 0,05389282 0,08513863 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05389282 0,08508276 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05389282 0,08502697 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05389282 0,08497125 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05389282 0,08491561 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05389282 0,08486003 ! cell killing GO:0001906 29 15 0,000 0,05389282 0,08480453 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,05389282 0,08474911 ! detection of bacterium GO:0016045 18 15 0,000 0,05389282 0,08469375 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05389282 0,08463847 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05389282 0,08458326 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05389282 0,08452812 ! peptide hormone processing GO:0016486 23 15 0,000 0,05389282 0,08447305 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,05738156 0,08988283 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,05738156 0,08982435 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05738156 0,08976595 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05738156 0,08970762 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05738156 0,08964937 ! bone remodeling GO:0046849 27 16 0,000 0,05738156 0,08959119 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,05738156 0,08953309 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05738156 0,08947507 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,05738156 0,08941712 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05738156 0,08935924 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,05738156 0,08930144 ! startle response GO:0001964 28 16 0,000 0,05738156 0,08924372 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05738156 0,08918607 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,05738156 0,08912849 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05738156 0,08907099 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,05738156 0,08901356 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05738156 0,0889562 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05738156 0,08889892 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05738156 0,08884172 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05738156 0,08878458 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05738156 0,08872753 ! response to osmotic stress GO:0006970 25 16 0,000 0,05738156 0,08867054 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,05738156 0,08861363 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,05738156 0,08855679 ! fructose metabolic process GO:0006000 25 16 0,000 0,05738156 0,08850002 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05738156 0,08844332 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05738156 0,0883867 ! intermediate filament-based process GO:0045103 32 16 0,000 0,05738156 0,08833015 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,05738156 0,08827368 ! negative regulation of immune response GO:0050777 35 16 0,000 0,05738156 0,08821727 ! axon cargo transport GO:0008088 43 16 0,000 0,05738156 0,08816094 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05738156 0,08810468 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05738156 0,08804849 ! neuron recognition GO:0008038 35 16 0,000 0,05738156 0,08799237 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05738156 0,08793632 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05738156 0,08788035 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05738156 0,08782445 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05738156 0,08776861 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05738156 0,08771285 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05738156 0,08765716 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05738156 0,08760154 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05738156 0,08754599 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05738156 0,08749051 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05738156 0,0874351 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,05738156 0,08737977 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,05738156 0,0873245 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06085754 0,09255578 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06085754 0,09249732 ! metencephalon development GO:0022037 30 17 0,000 0,06085754 0,09243892 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,06085754 0,0923806 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06085754 0,09232235 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06085754 0,09226418 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06085754 0,09220608 ! signal complex assembly GO:0007172 41 17 0,000 0,06085754 0,09214805 ! endothelial cell migration GO:0043542 28 17 0,000 0,06085754 0,0920901 ! inositol metabolic process GO:0006020 28 17 0,000 0,06085754 0,09203221 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06085754 0,0919744 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06085754 0,09191667 ! glial cell development GO:0021782 27 17 0,000 0,06085754 0,091859 ! limbic system development GO:0021761 36 17 0,000 0,06085754 0,09180141 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,06085754 0,09174389 ! adult walking behavior GO:0007628 33 17 0,000 0,06085754 0,09168644 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,06085754 0,09162907 ! heart looping GO:0001947 30 17 0,000 0,06085754 0,09157176 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06085754 0,09151453 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06085754 0,09145737 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06085754 0,09140028 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,06085754 0,09134326 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06085754 0,09128632 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06085754 0,09122944 ! glycine metabolic process GO:0006544 28 17 0,000 0,06085754 0,09117263 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06085754 0,0911159 ! NAD metabolic process GO:0019674 29 17 0,000 0,06085754 0,09105924 ! membrane budding GO:0006900 37 17 0,000 0,06085754 0,09100264 ! DNA integration GO:0015074 29 17 0,000 0,06085754 0,09094612 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,06085754 0,09088967 ! regulation of protein binding GO:0043393 33 17 0,000 0,06085754 0,09083328 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06085754 0,09077697 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06085754 0,09072073 ! genitalia development GO:0048806 30 17 0,000 0,06085754 0,09066455 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,06085754 0,09060845 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06085754 0,09055241 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,06085754 0,09049645 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,06085754 0,09044055 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06085754 0,09038472 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06085754 0,09032896 ! steroid catabolic process GO:0006706 31 17 0,000 0,06085754 0,09027327 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06085754 0,09021765 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,06085754 0,0901621 ! gas transport GO:0015669 25 17 0,000 0,06085754 0,09010662 ! organic cation transport GO:0015695 31 17 0,000 0,06085754 0,0900512 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06085754 0,08999585 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06085754 0,08994057 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,06085754 0,08988536 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,06085754 0,08983022 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06432083 0,09488406 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06432083 0,09482592 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,06432083 0,09476786 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,06432083 0,09470986 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06432083 0,09465193 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06432083 0,09459408 ! memory GO:0007613 31 18 0,000 0,06432083 0,09453629 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06432083 0,09447858 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06432083 0,09442093 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,06432083 0,09436336 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,06432083 0,09430586 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,06432083 0,09424842 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,06432083 0,09419106 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06432083 0,09413376 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,06432083 0,09407654 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,06432083 0,09401939 ! response to fungus GO:0009620 21 18 0,000 0,06432083 0,0939623 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,06432083 0,09390528 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,06432083 0,09384834 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,06432083 0,09379146 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,06432083 0,09373465 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06432083 0,09367791 ! vitamin transport GO:0051180 27 18 0,000 0,06432083 0,09362124 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,06432083 0,09356464 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06432083 0,0935081 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,06432083 0,09345164 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,06432083 0,09339524 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,06432083 0,09333891 ! nerve development GO:0021675 28 18 0,000 0,06432083 0,09328265 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06432083 0,09322645 ! protein secretion GO:0009306 39 19 0,000 0,06777145 0,09816864 ! positive regulation of translation GO:0045727 30 19 0,000 0,06777145 0,09810958 ! negative regulation of defense response GO:0031348 25 19 0,000 0,06777145 0,09805058 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,06777145 0,09799166 ! skin development GO:0043588 36 19 0,000 0,06777145 0,0979328 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,06777145 0,09787402 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06777145 0,09781531 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,06777145 0,09775666 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,06777145 0,09769809 ! bile acid metabolic process GO:0008206 29 19 0,000 0,06777145 0,09763959 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,06777145 0,09758116 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,06777145 0,0975228 ! cerebral cortex development GO:0021987 36 19 0,000 0,06777145 0,0974645 ! pigmentation during development GO:0048066 41 19 0,000 0,06777145 0,09740628 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,06777145 0,09734813 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,06777145 0,09729004 ! actin filament bundle formation GO:0051017 42 19 0,000 0,06777145 0,09723203 ! neuromuscular junction development GO:0007528 34 19 0,000 0,06777145 0,09717409 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,06777145 0,09711621 ! peptide cross-linking GO:0018149 37 19 0,000 0,06777145 0,0970584 ! heart process GO:0003015 30 19 0,000 0,06777145 0,09700066 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,06777145 0,09694299 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,06777145 0,09688539 ! visual learning GO:0008542 36 19 0,000 0,06777145 0,09682786 ! G1 phase GO:0051318 40 19 0,000 0,06777145 0,09677039 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,06777145 0,096713 ! cell-cell junction organization GO:0045216 35 19 0,000 0,06777145 0,09665567 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,06777145 0,09659841 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,06777145 0,09654122 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,06777145 0,09648409 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,06777145 0,09642703 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,06777145 0,09637004 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,06777145 0,09631312 ! cilium assembly GO:0042384 37 19 0,000 0,06777145 0,09625627 ! peptide hormone secretion GO:0030072 31 19 0,000 0,06777145 0,09619948 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,07120947 0,10102003 ! positive regulation of ossification GO:0045778 47 20 0,000 0,07120947 0,10096051 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,07120947 0,10090105 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,07120947 0,10084166 ! cAMP metabolic process GO:0046058 36 20 0,000 0,07120947 0,10078234 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,07120947 0,10072309 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,07120947 0,10066391 ! response to alkaloid GO:0043279 38 20 0,000 0,07120947 0,1006048 ! retinoid metabolic process GO:0001523 32 20 0,000 0,07120947 0,10054576 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,07120947 0,10048679 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,07120947 0,10042789 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,07120947 0,10036906 ! cellular response to starvation GO:0009267 33 20 0,000 0,07120947 0,10031029 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,07120947 0,1002516 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,07120947 0,10019297 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,07120947 0,10013441 ! peptide secretion GO:0002790 35 20 0,000 0,07120947 0,10007592 ! stem cell differentiation GO:0048863 53 20 0,000 0,07120947 0,1000175 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,07120947 0,09995915 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,07120947 0,09990086 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,07120947 0,09984265 ! sensory perception of pain GO:0019233 30 20 0,000 0,07120947 0,0997845 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,07120947 0,09972641 ! diencephalon development GO:0021536 34 20 0,000 0,07120947 0,0996684 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,07120947 0,09961045 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,07120947 0,09955257 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,07120947 0,09949476 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,07120947 0,09943702 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,07120947 0,09937934 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,07120947 0,09932173 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,07120947 0,09926418 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,07120947 0,0992067 ! regulation of glucose import GO:0046324 29 20 0,000 0,07120947 0,09914929 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,07120947 0,09909195 ! actin filament-based movement GO:0030048 43 20 0,000 0,07120947 0,09903467 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,07120947 0,09897746 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,07120947 0,09892031 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,07120947 0,09886323 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,07120947 0,09880622 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,07120947 0,09874927 ! regulation of cell killing GO:0031341 42 21 0,000 0,07463492 0,10343987 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,07463492 0,10338032 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,07463492 0,10332083 ! hormone secretion GO:0046879 38 21 0,000 0,07463492 0,10326142 ! glycerol metabolic process GO:0006071 34 21 0,000 0,07463492 0,10320207 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,07463492 0,1031428 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,07463492 0,10308359 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,07463492 0,10302445 ! axis specification GO:0009798 38 21 0,000 0,07463492 0,10296537 ! ovarian follicle development GO:0001541 35 21 0,000 0,07463492 0,10290637 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,07463492 0,10284743 ! smooth muscle contraction GO:0006939 46 21 0,000 0,07463492 0,10278856 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,07463492 0,10272975 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,07463492 0,10267102 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,07463492 0,10261235 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,07463492 0,10255375 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,07463492 0,10249521 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,07463492 0,10243674 ! cytolysis GO:0019835 24 21 0,000 0,07463492 0,10237834 ! vasodilation GO:0042311 39 21 0,000 0,07463492 0,10232001 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,07463492 0,10226174 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,07463492 0,10220353 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,07463492 0,1021454 ! oogenesis GO:0048477 36 21 0,000 0,07463492 0,10208733 ! collagen fibril organization GO:0030199 59 21 0,000 0,07463492 0,10202932 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,07463492 0,10197139 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,07463492 0,10191351 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,07463492 0,10185571 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,07463492 0,10179796 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,07463492 0,10174029 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,07463492 0,10168268 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,07463492 0,10162513 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,07463492 0,10156765 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,07463492 0,10151024 ! collagen catabolic process GO:0030574 28 21 0,000 0,07463492 0,10145289 ! sperm-egg recognition GO:0035036 21 21 0,000 0,07463492 0,1013956 ! gut development GO:0048565 39 21 0,000 0,07463492 0,10133838 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,07804785 0,10591264 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,07804785 0,10585294 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,07804785 0,10579331 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,07804785 0,10573374 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,07804785 0,10567424 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,07804785 0,1056148 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,07804785 0,10555543 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,07804785 0,10549613 ! regeneration GO:0031099 41 22 0,000 0,07804785 0,1054369 ! keratinization GO:0031424 28 22 0,000 0,07804785 0,10537773 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,07804785 0,10531863 ! sensory perception of taste GO:0050909 28 22 0,000 0,07804785 0,1052596 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,07804785 0,10520063 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,07804785 0,10514172 ! vacuolar transport GO:0007034 36 22 0,000 0,07804785 0,10508289 ! lysosome organization GO:0007040 41 22 0,000 0,07804785 0,10502412 ! central nervous system neuron development GO:0021954 46 22 0,000 0,07804785 0,10496541 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,07804785 0,10490677 ! fucose metabolic process GO:0006004 39 22 0,000 0,07804785 0,1048482 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,07804785 0,10478969 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,07804785 0,10473124 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,07804785 0,10467286 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,07804785 0,10461455 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,07804785 0,1045563 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,07804785 0,10449812 ! sarcomere organization GO:0045214 30 22 0,000 0,07804785 0,10444 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,07804785 0,10438194 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,07804785 0,10432395 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,07804785 0,10426603 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,07804785 0,10420817 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,07804785 0,10415037 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,07804785 0,10409264 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,0814483 0,10856765 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,0814483 0,10850754 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,0814483 0,10844749 ! gluconeogenesis GO:0006094 33 23 0,000 0,0814483 0,10838751 ! viral genome replication GO:0019079 41 23 0,000 0,0814483 0,10832759 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0814483 0,10826774 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0814483 0,10820796 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,0814483 0,10814824 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0814483 0,10808859 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,0814483 0,108029 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0814483 0,10796948 ! visual behavior GO:0007632 42 23 0,000 0,0814483 0,10791003 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,0814483 0,10785064 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,0814483 0,10779132 ! response to ethanol GO:0045471 46 23 0,000 0,0814483 0,10773206 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,0814483 0,10767286 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,0814483 0,10761374 ! peroxisome organization GO:0007031 37 23 0,000 0,0814483 0,10755467 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0814483 0,10749567 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,0814483 0,10743674 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,0814483 0,10737787 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0814483 0,10731907 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,0814483 0,10726032 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,0814483 0,10720165 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,0814483 0,10714304 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0814483 0,10708449 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0814483 0,107026 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0814483 0,10696758 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0814483 0,10690923 ! fatty acid transport GO:0015908 44 23 0,000 0,0814483 0,10685093 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,0814483 0,1067927 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0814483 0,10673454 ! hormone transport GO:0009914 40 23 0,000 0,0814483 0,10667644 ! cell-cell recognition GO:0009988 25 23 0,000 0,0814483 0,1066184 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0814483 0,10656042 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0814483 0,10650251 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,0814483 0,10644466 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0814483 0,10638687 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,0814483 0,10632914 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,08483633 0,11069208 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,08483633 0,11063209 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,08483633 0,11057216 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,08483633 0,11051229 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,08483633 0,11045249 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,08483633 0,11039275 ! vesicle docking GO:0048278 47 24 0,000 0,08483633 0,11033308 ! spinal cord development GO:0021510 47 24 0,000 0,08483633 0,11027347 ! vacuole organization GO:0007033 43 24 0,000 0,08483633 0,11021393 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,08483633 0,11015445 ! digestive system process GO:0022600 39 24 0,000 0,08483633 0,11009504 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,08483633 0,11003569 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,08483633 0,1099764 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,08483633 0,10991718 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,08483633 0,10985802 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,08483633 0,10979893 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,08483633 0,10973989 ! membrane depolarization GO:0051899 39 24 0,000 0,08483633 0,10968093 ! pallium development GO:0021543 49 24 0,000 0,08483633 0,10962202 ! pentose metabolic process GO:0019321 35 24 0,000 0,08483633 0,10956318 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,08483633 0,1095044 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,08483633 0,10944568 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,08483633 0,10938703 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,08483633 0,10932844 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,08483633 0,10926992 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,08483633 0,10921145 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,08483633 0,10915305 ! regulation of amine transport GO:0051952 40 24 0,000 0,08483633 0,10909471 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,08821197 0,113375 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,08821197 0,11331447 ! myelination GO:0042552 45 25 0,000 0,08821197 0,113254 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,08821197 0,1131936 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,08821197 0,11313326 ! phototransduction GO:0007602 33 25 0,000 0,08821197 0,11307299 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,08821197 0,11301278 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,08821197 0,11295263 ! sperm motility GO:0030317 31 25 0,000 0,08821197 0,11289255 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,08821197 0,11283253 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,08821197 0,11277258 ! receptor metabolic process GO:0043112 46 25 0,000 0,08821197 0,11271269 ! chromosome condensation GO:0030261 45 25 0,000 0,08821197 0,11265286 ! response to starvation GO:0042594 42 25 0,000 0,08821197 0,1125931 ! osteoblast differentiation GO:0001649 60 25 0,000 0,08821197 0,1125334 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,08821197 0,11247376 ! neural crest cell development GO:0014032 54 25 0,000 0,08821197 0,11241419 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,08821197 0,11235468 ! negative regulation of cell development GO:0010721 73 25 0,000 0,08821197 0,11229524 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,08821197 0,11223585 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,08821197 0,11217653 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,08821197 0,11211727 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,08821197 0,11205808 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,08821197 0,11199894 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,08821197 0,11193987 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,08821197 0,11188086 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,08821197 0,11182191 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,08821197 0,11176303 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,08821197 0,11170421 ! telomere organization GO:0032200 43 25 0,000 0,08821197 0,11164545 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,08821197 0,11158675 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,08821197 0,11152811 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,09157527 0,11571959 ! embryonic pattern specification GO:0009880 44 26 0,000 0,09157527 0,11565884 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,09157527 0,11559816 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,09157527 0,11553754 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,09157527 0,11547699 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,09157527 0,1154165 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,09157527 0,11535607 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,09157527 0,11529571 ! molting cycle process GO:0022404 50 26 0,000 0,09157527 0,11523541 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,09157527 0,11517517 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,09157527 0,11511499 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,09157527 0,11505488 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,09157527 0,11499483 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,09157527 0,11493485 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,09157527 0,11487492 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,09157527 0,11481506 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,09157527 0,11475526 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,09157527 0,11469552 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,09157527 0,11463585 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,09157527 0,11457623 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,09157527 0,11451668 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,09157527 0,11445719 ! blastocyst development GO:0001824 49 26 0,000 0,09157527 0,11439777 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,09157527 0,1143384 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,09157527 0,1142791 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,09492628 0,11839949 ! neuron fate commitment GO:0048663 48 27 0,000 0,09492628 0,11833815 ! iron ion transport GO:0006826 59 27 0,000 0,09492628 0,11827686 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,09492628 0,11821564 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,09492628 0,11815449 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,09492628 0,11809339 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,09492628 0,11803236 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,09492628 0,11797139 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,09492628 0,11791049 ! autophagy GO:0006914 41 27 0,000 0,09492628 0,11784965 ! male gonad development GO:0008584 44 27 0,000 0,09492628 0,11778887 ! response to toxin GO:0009636 47 27 0,000 0,09492628 0,11772815 ! primary neural tube formation GO:0014020 51 27 0,000 0,09492628 0,1176675 ! base-excision repair GO:0006284 41 27 0,000 0,09492628 0,11760691 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,09492628 0,11754638 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,09492628 0,11748592 ! glutathione metabolic process GO:0006749 39 27 0,000 0,09492628 0,11742551 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,09492628 0,11736517 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,09492628 0,11730489 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,09492628 0,11724467 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,09826503 0,12130614 ! circadian rhythm GO:0007623 50 28 0,000 0,09826503 0,12124393 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,09826503 0,12118179 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,09826503 0,12111971 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,09826503 0,12105769 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,09826503 0,12099574 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,09826503 0,12093385 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,09826503 0,12087202 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,09826503 0,12081025 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,09826503 0,12074855 ! synaptogenesis GO:0007416 42 28 0,000 0,09826503 0,12068692 ! lipid oxidation GO:0034440 43 28 0,000 0,09826503 0,12062534 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,09826503 0,12056383 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,09826503 0,12050238 ! translational initiation GO:0006413 65 29 0,000 0,10159158 0,12451826 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,10159158 0,12445486 ! regulation of pH GO:0006885 43 29 0,000 0,10159158 0,12439153 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,10159158 0,12432826 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,10159158 0,12426505 ! catechol metabolic process GO:0009712 54 29 0,000 0,10159158 0,12420191 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,10159158 0,12413883 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,10159158 0,12407581 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,10159158 0,12401286 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,10159158 0,12394997 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,10159158 0,12388715 ! cell fate determination GO:0001709 60 29 0,000 0,10159158 0,12382439 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,10159158 0,1237617 ! detection of light stimulus GO:0009583 38 29 0,000 0,10159158 0,12369906 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,10159158 0,12363649 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,10159158 0,12357399 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,10159158 0,12351155 ! tissue homeostasis GO:0001894 48 29 0,000 0,10159158 0,12344917 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,10159158 0,12338685 ! phenol metabolic process GO:0018958 55 30 0,000 0,10490597 0,12734802 ! zinc ion transport GO:0006829 45 30 0,000 0,10490597 0,1272838 ! membrane docking GO:0022406 61 30 0,000 0,10490597 0,12721964 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,10490597 0,12715555 ! cell junction assembly GO:0034329 78 30 0,000 0,10490597 0,12709153 ! regulation of innate immune response GO:0045088 51 30 0,000 0,10490597 0,12702756 ! acute-phase response GO:0006953 49 30 0,000 0,10490597 0,12696367 ! myofibril assembly GO:0030239 47 30 0,000 0,10490597 0,12689983 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,10490597 0,12683606 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,10490597 0,12677236 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,10490597 0,12670872 ! phospholipid transport GO:0015914 51 30 0,000 0,10490597 0,12664514 ! ensheathment of neurons GO:0007272 57 30 0,000 0,10490597 0,12658163 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,10490597 0,12651818 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,10490597 0,12645479 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,10490597 0,12639147 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,10490597 0,12632821 ! eye morphogenesis GO:0048592 60 30 0,000 0,10490597 0,12626502 ! regulation of B cell activation GO:0050864 50 30 0,000 0,10490597 0,12620188 ! response to heat GO:0009408 50 30 0,000 0,10490597 0,12613882 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,10820824 0,13004447 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,10820824 0,12997955 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,10820824 0,12991469 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,10820824 0,12984989 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,10820824 0,12978516 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,10820824 0,1297205 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,10820824 0,12965589 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,10820824 0,12959136 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,10820824 0,12952688 ! ovulation cycle process GO:0022602 49 31 0,000 0,10820824 0,12946247 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,10820824 0,12939813 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,10820824 0,12933385 ! peptide transport GO:0015833 55 31 0,000 0,10820824 0,12926963 ! iron ion homeostasis GO:0055072 54 31 0,000 0,10820824 0,12920548 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,10820824 0,12914139 ! mesoderm formation GO:0001707 69 31 0,000 0,10820824 0,12907736 ! natural killer cell activation GO:0030101 45 31 0,000 0,10820824 0,1290134 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,10820824 0,1289495 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,10820824 0,12888566 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,10820824 0,12882189 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,10820824 0,12875818 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,10820824 0,12869453 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,11149844 0,13254212 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,11149844 0,13247667 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,11149844 0,13241128 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,11149844 0,13234595 ! cholesterol transport GO:0030301 56 32 0,000 0,11149844 0,13228069 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,11149844 0,1322155 ! spliceosome assembly GO:0000245 67 32 0,000 0,11149844 0,13215037 ! spindle organization GO:0007051 46 32 0,000 0,11149844 0,1320853 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,11149844 0,1320203 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,11149844 0,13195536 ! response to ionizing radiation GO:0010212 65 32 0,000 0,11149844 0,13189049 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,11149844 0,13182568 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,11149844 0,13176093 ! muscle cell development GO:0055001 49 32 0,000 0,11149844 0,13169624 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,11149844 0,13163162 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,11149844 0,13156707 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,11149844 0,13150257 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,11149844 0,13143814 ! ovulation cycle GO:0042698 51 32 0,000 0,11149844 0,13137378 ! peripheral nervous system development GO:0007422 64 32 0,000 0,11149844 0,13130947 ! BMP signaling pathway GO:0030509 64 32 0,000 0,11149844 0,13124523 ! hindbrain development GO:0030902 61 32 0,000 0,11149844 0,13118105 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,11149844 0,13111694 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,11149844 0,13105288 ! gene silencing GO:0016458 65 32 0,000 0,11149844 0,13098889 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,11477661 0,13477429 ! post-embryonic development GO:0009791 69 33 0,000 0,11477661 0,13470855 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,11477661 0,13464287 ! protein targeting to membrane GO:0006612 68 33 0,000 0,11477661 0,13457725 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,11477661 0,1345117 ! ceramide metabolic process GO:0006672 64 33 0,000 0,11477661 0,13444621 ! formation of primary germ layer GO:0001704 72 33 0,000 0,11477661 0,13438079 ! cell fate specification GO:0001708 52 33 0,000 0,11477661 0,13431543 ! sterol transport GO:0015918 57 33 0,000 0,11477661 0,13425013 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,11477661 0,1341849 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,11477661 0,13411973 ! adult locomotory behavior GO:0008344 59 33 0,000 0,11477661 0,13405462 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,11477661 0,13398958 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,11477661 0,1339246 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,11804279 0,13766891 ! glial cell differentiation GO:0010001 63 34 0,000 0,11804279 0,13760221 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,11804279 0,13753557 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,11804279 0,137469 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,11804279 0,13740249 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,11804279 0,13733605 ! mismatch repair GO:0006298 46 34 0,000 0,11804279 0,13726967 ! spermatid development GO:0007286 63 34 0,000 0,11804279 0,13720336 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,11804279 0,13713711 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,11804279 0,13707092 ! placenta development GO:0001890 53 34 0,000 0,11804279 0,1370048 ! regulation of muscle development GO:0048634 70 35 0,000 0,12129703 0,14071391 ! negative regulation of secretion GO:0051048 63 35 0,000 0,12129703 0,1406461 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,12129703 0,14057835 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,12129703 0,14051066 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,12129703 0,14044305 ! odontogenesis GO:0042476 66 35 0,000 0,12129703 0,14037549 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,12129703 0,140308 ! female gonad development GO:0008585 58 35 0,000 0,12129703 0,14024058 ! telencephalon development GO:0021537 68 35 0,000 0,12129703 0,14017322 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,12129703 0,14010593 ! cytokine production GO:0001816 59 35 0,000 0,12129703 0,1400387 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,12129703 0,13997153 ! neural tube formation GO:0001841 67 35 0,000 0,12129703 0,13990443 ! vesicle localization GO:0051648 64 35 0,000 0,12129703 0,1398374 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,12453937 0,14350657 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,12453937 0,14343787 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,12453937 0,14336924 ! cell junction organization GO:0034330 86 36 0,000 0,12453937 0,14330068 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,12453937 0,14323218 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,12453937 0,14316374 ! positive regulation of cell development GO:0010720 80 36 0,000 0,12453937 0,14309538 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,12453937 0,14302707 ! regulation of proteolysis GO:0030162 72 36 0,000 0,12453937 0,14295883 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,12453937 0,14289066 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,12453937 0,14282255 ! aerobic respiration GO:0009060 55 36 0,000 0,12453937 0,14275451 ! embryonic organ development GO:0048568 57 36 0,000 0,12453937 0,14268653 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,12453937 0,14261862 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,12453937 0,14255077 ! RNA export from nucleus GO:0006405 56 37 0,000 0,12776985 0,14617891 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,12776985 0,14610944 ! meiosis I GO:0007127 65 37 0,000 0,12776985 0,14604003 ! sister chromatid segregation GO:0000819 58 37 0,000 0,12776985 0,14597068 ! actomyosin structure organization GO:0031032 62 37 0,000 0,12776985 0,1459014 ! organic anion transport GO:0015711 68 37 0,000 0,12776985 0,14583219 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,12776985 0,14576304 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,12776985 0,14569396 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,12776985 0,14562494 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,12776985 0,14555599 ! pigment metabolic process GO:0042440 80 37 0,000 0,12776985 0,14548711 ! spermatid differentiation GO:0048515 66 37 0,000 0,12776985 0,14541829 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,13098852 0,14901105 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,13098852 0,14894063 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,13098852 0,14887028 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,13098852 0,14879999 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,13098852 0,14872977 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,13098852 0,14865961 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,13098852 0,14858952 ! lipid homeostasis GO:0055088 67 38 0,000 0,13098852 0,1485195 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,13098852 0,14844954 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,13098852 0,14837965 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,13098852 0,14830982 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,13098852 0,14824006 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,13098852 0,14817037 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,13098852 0,14810074 ! glucan metabolic process GO:0044042 62 38 0,000 0,13098852 0,14803118 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,13419542 0,15158412 ! mammary gland development GO:0030879 86 39 0,000 0,13419542 0,15151298 ! learning GO:0007612 77 39 0,000 0,13419542 0,15144192 ! ear morphogenesis GO:0042471 60 39 0,000 0,13419542 0,15137092 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,13419542 0,15129999 ! ion transmembrane transport GO:0034220 66 39 0,000 0,13419542 0,15122912 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,13419542 0,15115832 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,13419542 0,15108758 ! RNA modification GO:0009451 57 39 0,000 0,13419542 0,15101692 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,13419542 0,15094632 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,13739058 0,15446811 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,13739058 0,15439596 ! feeding behavior GO:0007631 59 40 0,000 0,13739058 0,15432388 ! negative regulation of binding GO:0051100 72 40 0,000 0,13739058 0,15425186 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,13739058 0,15417992 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,13739058 0,15410804 ! maintenance of protein location GO:0045185 91 40 0,000 0,13739058 0,15403623 ! cytokinesis GO:0000910 72 40 0,000 0,13739058 0,15396448 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,14057407 0,15745866 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,14057407 0,15738539 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,14057407 0,15731219 ! gliogenesis GO:0042063 88 41 0,000 0,14057407 0,15723906 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,14057407 0,15716599 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,14057407 0,15709299 ! T cell differentiation GO:0030217 81 41 0,000 0,14057407 0,15702006 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,14057407 0,1569472 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,14057407 0,1568744 ! female gamete generation GO:0007292 61 41 0,000 0,14057407 0,15680167 ! polyol metabolic process GO:0019751 66 41 0,000 0,14057407 0,15672901 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,14057407 0,15665642 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,14374591 0,16011697 ! regulation of tube size GO:0035150 71 42 0,000 0,14374591 0,16004288 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,14374591 0,15996885 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,14374591 0,15989489 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,14374591 0,15982101 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,14374591 0,15974719 ! regulation of protein secretion GO:0050708 71 42 0,000 0,14374591 0,15967343 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,14690615 0,16310853 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,14690615 0,1630333 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,14690615 0,16295813 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,14690615 0,16288304 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,14690615 0,16280801 ! glucose transport GO:0015758 65 43 0,000 0,14690615 0,16273305 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,14690615 0,16265817 ! neural tube development GO:0021915 77 43 0,000 0,14690615 0,16258335 ! striated muscle contraction GO:0006941 77 43 0,000 0,14690615 0,16250859 ! phagocytosis GO:0006909 90 43 0,000 0,14690615 0,16243391 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,14690615 0,1623593 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,15005483 0,16576305 ! hexose transport GO:0008645 67 44 0,000 0,15005483 0,16568698 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,15005483 0,16561097 ! male sex differentiation GO:0046661 76 44 0,000 0,15005483 0,16553504 ! double-strand break repair GO:0006302 81 44 0,000 0,15005483 0,16545917 ! B cell differentiation GO:0030183 107 44 0,000 0,15005483 0,16538338 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,15005483 0,16530766 ! developmental growth GO:0048589 82 44 0,000 0,15005483 0,165232 ! maintenance of location in cell GO:0051651 97 44 0,000 0,15005483 0,16515641 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,15319199 0,16853221 ! glycolysis GO:0006096 65 45 0,000 0,15319199 0,16845518 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,15319199 0,16837822 ! leukocyte migration GO:0050900 68 45 0,000 0,15319199 0,16830134 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,15319199 0,16822452 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,15319199 0,16814778 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,15319199 0,16807111 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,15319199 0,1679945 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,15319199 0,16791797 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,15319199 0,1678415 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,15319199 0,1677651 ! cell growth GO:0016049 84 45 0,000 0,15319199 0,16768878 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,15631768 0,17103244 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,15631768 0,1709547 ! positive regulation of defense response GO:0031349 76 47 0,000 0,15943193 0,17428134 ! endosome transport GO:0016197 108 47 0,000 0,15943193 0,1742022 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,15943193 0,17412312 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,15943193 0,17404412 ! JNK cascade GO:0007254 91 47 0,000 0,15943193 0,17396519 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,15943193 0,17388633 ! mitochondrial transport GO:0006839 82 48 0,000 0,1625348 0,17719018 ! cellular component disassembly GO:0022411 86 48 0,000 0,1625348 0,17710993 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,1625348 0,17702975 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,1625348 0,17694965 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,1625348 0,17686962 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,1625348 0,17678966 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,1625348 0,17670977 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,1625348 0,17662995 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,1625348 0,17655021 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,16562631 0,17982712 ! regulation of action potential GO:0001508 95 49 0,000 0,16562631 0,17974601 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,16562631 0,17966497 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,16562631 0,179584 ! regulation of ion transport GO:0043269 77 49 0,000 0,16562631 0,17950311 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,16562631 0,17942229 ! peptide metabolic process GO:0006518 76 49 0,000 0,16562631 0,17934154 ! response to temperature stimulus GO:0009266 76 49 0,000 0,16562631 0,17926086 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,16562631 0,17918026 ! endocrine system development GO:0035270 104 49 0,000 0,16562631 0,17909973 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,16562631 0,17901927 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,16562631 0,17893888 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,16562631 0,17885857 ! neuromuscular process GO:0050905 99 50 0,000 0,16870651 0,18210312 ! regulation of ossification GO:0030278 117 50 0,000 0,16870651 0,18202146 ! inner ear development GO:0048839 79 50 0,000 0,16870651 0,18193987 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,16870651 0,18185836 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,16870651 0,18177692 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,17177544 0,18500076 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,17177544 0,18491799 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,17177544 0,18483529 ! chromatin remodeling GO:0006338 109 51 0,000 0,17177544 0,18475266 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,17177544 0,18467011 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,17177544 0,18458763 ! vesicle organization GO:0016050 107 51 0,000 0,17177544 0,18450523 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,17177544 0,1844229 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 81 52 0,000 0,17483314 0,18762201 ! cartilage development GO:0051216 90 52 0,000 0,17483314 0,18753836 ! synapse organization GO:0050808 85 52 0,000 0,17483314 0,18745479 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,17787966 0,19063629 ! RNA catabolic process GO:0006401 93 53 0,000 0,17787966 0,19055141 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,17787966 0,19046661 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,17787966 0,19038188 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,17787966 0,19029723 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,18091503 0,19345847 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,18091503 0,19337253 ! cell recognition GO:0008037 85 54 0,000 0,18091503 0,19328666 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,18091503 0,19320087 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,18091503 0,19311516 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,18091503 0,19302952 ! chloride transport GO:0006821 90 55 0,000 0,18393929 0,1961693 ! glucose catabolic process GO:0006007 82 55 0,000 0,18393929 0,19608238 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,18393929 0,19599555 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,18393929 0,19590878 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,18393929 0,1958221 ! gastrulation GO:0007369 112 55 0,000 0,18393929 0,19573549 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,18393929 0,19564896 ! regulation of actin filament length GO:0030832 105 56 0,000 0,18695249 0,1987661 ! sensory perception of smell GO:0007608 80 56 0,000 0,18695249 0,19867831 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,18695249 0,19859059 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,18695249 0,19850295 ! proton transport GO:0015992 94 56 0,000 0,18695249 0,19841539 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,18695249 0,19832791 ! hydrogen transport GO:0006818 97 58 0,000 0,19294585 0,20459573 ! adult behavior GO:0030534 99 58 0,000 0,19294585 0,2045056 ! regulation of cellular component size GO:0032535 109 59 0,000 0,19592609 0,20757295 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,19592609 0,20748159 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,19592609 0,20739031 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,19592609 0,20729911 ! DNA catabolic process GO:0006308 86 59 0,000 0,19592609 0,20720798 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,19889542 0,21025588 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,19889542 0,21016354 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,19889542 0,21007128 ! regulation of heart contraction GO:0008016 110 60 0,000 0,19889542 0,2099791 ! camera-type eye development GO:0043010 116 60 0,000 0,19889542 0,20988701 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,20185389 0,21291558 ! tRNA processing GO:0008033 89 61 0,000 0,20185389 0,21282228 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,20185389 0,21272906 ! ear development GO:0043583 103 62 0,000 0,20480152 0,21574101 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,20480152 0,21564659 ! gonad development GO:0008406 98 62 0,000 0,20480152 0,21555226 ! detection of external stimulus GO:0009581 91 63 0,000 0,20773837 0,21854767 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,20773837 0,21845215 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,21066448 0,22143238 ! cell redox homeostasis GO:0045454 102 64 0,000 0,21066448 0,22133569 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,21066448 0,22123908 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,21066448 0,22114255 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,21066448 0,22104611 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,21357987 0,22400748 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,21357987 0,22390987 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,21357987 0,22381235 GO:0035113|embryonic appendage morphogenesis, ! actin filament organization GO:0007015 148 66 0,000 0,21648459 0,22675747 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,21648459 0,2266588 ! extracellular matrix organization GO:0030198 133 66 0,000 0,21648459 0,22656021 ! secondary metabolic process GO:0019748 116 66 0,000 0,21648459 0,2264617 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,21937867 0,22938943 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,21937867 0,22928979 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,21937867 0,22919022 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,21937867 0,22909075 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,21937867 0,22899136 ! hexose catabolic process GO:0019320 104 67 0,000 0,21937867 0,22889206 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,21937867 0,22879284 ! activation of immune response GO:0002253 105 67 0,000 0,21937867 0,22869371 ! amino acid transport GO:0006865 125 68 0,000 0,22226217 0,23159929 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,22226217 0,23149904 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,22226217 0,23139886 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,22226217 0,23129878 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,22226217 0,23119878 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,2251351 0,23408602 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,2251351 0,23398491 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,2251351 0,23388388 ! appendage morphogenesis GO:0035107 135 70 0,000 0,22799752 0,23675531 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,23084946 0,23961338 ! reproductive structure development GO:0048608 113 71 0,000 0,23084946 0,23951005 ! appendage development GO:0048736 136 71 0,000 0,23084946 0,23940682 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,23084946 0,23930367 ! B cell activation GO:0042113 160 71 0,000 0,23084946 0,23920061 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,23084946 0,23909764 ! regulation of immune effector process GO:0002697 137 71 0,000 0,23084946 0,23899476 ! acute inflammatory response GO:0002526 113 72 0,000 0,23369096 0,24183246 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,23369096 0,24172849 ! carbohydrate transport GO:0008643 110 72 0,000 0,23369096 0,24162461 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,23369096 0,24152082 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,23369096 0,24141712 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,23369096 0,2413135 ! learning or memory GO:0007611 147 73 0,000 0,23652206 0,24413217 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,23652206 0,24402748 ! fertilization GO:0009566 90 73 0,000 0,23652206 0,24392288 ! transition metal ion transport GO:0000041 126 74 0,000 0,23934279 0,24672612 ! neurotransmitter transport GO:0006836 123 74 0,000 0,23934279 0,24662045 ! meiosis GO:0007126 121 74 0,000 0,23934279 0,24651488 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,23934279 0,2464094 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,23934279 0,246304 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,23934279 0,2461987 ! eye development GO:0001654 143 74 0,000 0,23934279 0,24609349 ! meiotic cell cycle GO:0051321 122 75 0,000 0,2421532 0,2488768 ! rhythmic process GO:0048511 128 75 0,000 0,2421532 0,24877053 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,2421532 0,24866436 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,24495331 0,25143245 ! defense response to bacterium GO:0042742 89 76 0,000 0,24495331 0,25132523 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,24495331 0,2512181 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,24495331 0,25111106 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,24774317 0,25386289 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,24774317 0,25375482 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,24774317 0,25364684 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,24774317 0,25353895 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,25052281 0,25627461 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,25052281 0,2561657 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,25329228 0,25888752 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,25329228 0,25877759 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,25329228 0,25866775 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,25329228 0,25855801 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,25329228 0,25844836 ! inorganic anion transport GO:0015698 138 80 0,000 0,2560516 0,2611531 ! digestion GO:0007586 112 81 0,000 0,25880082 0,26384524 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,26153997 0,26652485 ! negative regulation of transport GO:0051051 153 84 0,000 0,26698821 0,27196174 ! regulation of ligase activity GO:0051340 142 84 0,000 0,26698821 0,27184665 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,26698821 0,27173166 ! response to unfolded protein GO:0006986 131 85 0,000 0,26969737 0,27437289 ! nucleosome assembly GO:0006334 122 85 0,000 0,26969737 0,27425692 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,26969737 0,27414106 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,27239662 0,27676784 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,27239662 0,27665102 ! chromatin assembly GO:0031497 124 86 0,000 0,27239662 0,27653429 ! mitochondrion organization GO:0007005 148 86 0,000 0,27239662 0,27641765 ! alcohol catabolic process GO:0046164 130 86 0,000 0,27239662 0,27630112 ! amine transport GO:0015837 155 86 0,000 0,27239662 0,27618468 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,27508597 0,27879395 ! cellular respiration GO:0045333 135 88 0,000 0,27776547 0,28139104 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,27776547 0,28127261 ! gland development GO:0048732 206 88 0,000 0,27776547 0,28115428 ! regulation of neurological system process GO:0031644 148 88 0,000 0,27776547 0,28103605 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,27776547 0,28091792 ! cellular defense response GO:0006968 114 89 0,000 0,28043516 0,28349874 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,28043516 0,28337967 ! sex differentiation GO:0007548 145 90 0,000 0,28309507 0,28594741 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,28309507 0,28582741 ! sterol metabolic process GO:0016125 152 91 0,000 0,28574523 0,28838214 ! response to protein stimulus GO:0051789 149 91 0,000 0,28574523 0,28826122 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,28574523 0,28814041 ! regulation of defense response GO:0031347 149 92 0,000 0,28838568 0,29068117 ! nucleosome organization GO:0034728 138 92 0,000 0,28838568 0,29055944 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,28838568 0,29043782 ! vitamin metabolic process GO:0006766 139 92 0,000 0,28838568 0,2903163 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,29101646 0,29284216 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,29101646 0,29271974 ! regulation of membrane potential GO:0042391 164 93 0,000 0,29101646 0,29259741 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,29363761 0,29510947 ! female pregnancy GO:0007565 164 94 0,000 0,29363761 0,29498625 ! regulation of T cell activation GO:0050863 158 94 0,000 0,29363761 0,29486314 ! forebrain development GO:0030900 188 95 0,000 0,29624914 0,29736147 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,29885111 0,29984812 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,29885111 0,29972313 ! detection of stimulus GO:0051606 151 96 0,000 0,29885111 0,29959824 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,30144355 0,3020713 ! protein ubiquitination GO:0016567 217 97 0,000 0,30144355 0,30194554 ! hormone metabolic process GO:0042445 157 97 0,000 0,30144355 0,30181988 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,30402649 0,30427942 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,30402649 0,3041529 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,30659996 0,30659996