pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1126-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 4,000 2,443E-10 5,968E-07 ! Notch receptor processing GO:0007220 11 5 2,000 4,431E-07 5,413E-04 ! myoblast cell fate commitment GO:0048625 18 6 2,000 8,84E-07 7,198E-04 ! nuclear migration GO:0007097 13 6 2,000 8,84E-07 5,399E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 8,84E-07 4,319E-04 GO:0031272|regulation of pseudopodium assembly, ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 4,000 1,222E-06 4,976E-04 ! amyloid precursor protein catabolic process GO:0042987 15 7 2,000 1,543E-06 5,385E-04 ! RNA elongation GO:0006354 90 56 4,000 1,776E-06 5,423E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 2,462E-06 6,683E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 2,462E-06 6,015E-04 ! regulation of vascular permeability GO:0043114 12 8 2,000 2,462E-06 5,468E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 2,462E-06 5,013E-04 ! amyloid precursor protein metabolic process GO:0042982 18 9 2,000 3,684E-06 6,922E-04 ! macrophage differentiation GO:0030225 15 9 2,000 3,684E-06 6,428E-04 ! protein sumoylation GO:0016925 17 10 2,000 5,249E-06 8,548E-04 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 7,198E-06 1,099E-03 ! nucleus localization GO:0051647 22 11 2,000 7,198E-06 1,034E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 9,572E-06 1,299E-03 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 9,572E-06 1,231E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 4,000 1,109E-05 1,355E-03 ! carbohydrate homeostasis GO:0033500 59 39 3,000 1,16E-05 1,35E-03 GO:0042593|glucose homeostasis, ! cGMP metabolic process GO:0046068 18 13 2,000 1,241E-05 1,378E-03 GO:0006182|cGMP biosynthetic process, ! membrane protein proteolysis GO:0033619 33 13 2,000 1,241E-05 1,318E-03 GO:0006509|membrane protein ectodomain proteolysis, ! establishment or maintenance of cell polarity GO:0007163 96 41 3,000 1,421E-05 1,446E-03 ! glycoprotein catabolic process GO:0006516 33 15 2,000 1,964E-05 1,919E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 1,964E-05 1,846E-03 ! branching morphogenesis of a tube GO:0048754 102 45 3,000 2,067E-05 1,871E-03 ! transcription initiation GO:0006352 171 97 4,000 2,665E-05 2,325E-03 ! filopodium assembly GO:0046847 42 17 2,000 2,92E-05 2,46E-03 ! myoblast differentiation GO:0045445 50 17 2,000 2,92E-05 2,378E-03 ! patterning of blood vessels GO:0001569 43 18 2,000 3,495E-05 2,754E-03 ! response to retinoic acid GO:0032526 31 18 2,000 3,495E-05 2,668E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 3,495E-05 2,587E-03 ! microspike assembly GO:0030035 46 18 2,000 3,495E-05 2,511E-03 ! morphogenesis of a branching structure GO:0001763 116 52 3,000 3,684E-05 2,572E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 4,14E-05 2,809E-03 ! response to vitamin A GO:0033189 32 19 2,000 4,14E-05 2,733E-03 ! regulation of angiogenesis GO:0045765 125 54 3,000 4,28E-05 2,752E-03 ! regulation of cell shape GO:0008360 142 54 3,000 4,28E-05 2,681E-03 ! response to vitamin GO:0033273 36 20 2,000 4,857E-05 2,967E-03 ! pancreas development GO:0031016 40 20 2,000 4,857E-05 2,894E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 5,652E-05 3,288E-03 ! negative regulation of angiogenesis GO:0016525 49 21 2,000 5,652E-05 3,211E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 5,679E-05 3,153E-03 ! viral reproductive process GO:0022415 132 62 3,000 7,385E-05 4,009E-03 ! positive regulation of DNA replication GO:0045740 44 23 2,000 7,487E-05 3,976E-03 ! platelet activation GO:0030168 41 24 2,000 8,534E-05 4,436E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 8,89E-05 4,524E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 9,437E-05 4,705E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 9,673E-05 4,726E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 9,673E-05 4,634E-03 ! interaction with host GO:0051701 66 25 2,000 9,673E-05 4,544E-03 ! viral reproduction GO:0016032 142 68 3,000 1,06E-04 4,888E-03 ! initiation of viral infection GO:0019059 60 26 2,000 1,091E-04 4,934E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 1,224E-04 5,436E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 1,224E-04 5,339E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 3,000 1,255E-04 5,378E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,258E-04 5,298E-03 ! protein maturation by protein folding GO:0022417 14 5 1,000 1,258E-04 5,208E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 1,258E-04 5,121E-03 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 1,258E-04 5,037E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,258E-04 4,956E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,258E-04 4,877E-03 ! sequestering of calcium ion GO:0051208 7 5 1,000 1,258E-04 4,801E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 1,258E-04 4,727E-03 ! fat cell differentiation GO:0045444 57 28 2,000 1,367E-04 5,06E-03 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 2,000 1,367E-04 4,984E-03 ! regulation of caspase activity GO:0043281 136 74 3,000 1,474E-04 5,295E-03 ! regulation of peptide secretion GO:0002791 52 29 2,000 1,521E-04 5,384E-03 ! regulation of blood pressure GO:0008217 134 76 3,000 1,634E-04 5,704E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 1,685E-04 5,799E-03 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 1,719E-04 5,833E-03 ! neuronal ion channel clustering GO:0045161 15 6 1,000 1,882E-04 6,299E-03 ! triglyceride catabolic process GO:0019433 10 6 1,000 1,882E-04 6,214E-03 ! response to hypoxia GO:0001666 178 81 3,000 2,09E-04 6,809E-03 ! regulation of peptidase activity GO:0052547 150 82 3,000 2,191E-04 7,044E-03 ! response to oxygen levels GO:0070482 183 83 3,000 2,296E-04 7,285E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 2,458E-04 7,699E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 2,629E-04 8,13E-03 ! mRNA stabilization GO:0048255 18 7 1,000 2,629E-04 8,028E-03 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 16 7 1,000 2,629E-04 7,929E-03 GO:0031958|corticosteroid receptor signaling pathway, ! glycerol ether catabolic process GO:0044269 12 7 1,000 2,629E-04 7,832E-03 GO:0046464|acylglycerol catabolic process, ! male sex determination GO:0030238 15 7 1,000 2,629E-04 7,738E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 1,000 2,629E-04 7,646E-03 ! regulation of meiosis GO:0040020 12 7 1,000 2,629E-04 7,556E-03 GO:0051445|regulation of meiotic cell cycle, ! diuresis GO:0030146 12 7 1,000 2,629E-04 7,468E-03 GO:0030147|natriuresis, ! tube morphogenesis GO:0035239 194 89 3,000 3,001E-04 8,427E-03 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 3,167E-04 8,792E-03 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 3,43E-04 9,414E-03 ! cyclic nucleotide metabolic process GO:0009187 69 38 2,000 3,43E-04 9,309E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 3,43E-04 9,207E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 3,497E-04 9,286E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 3,497E-04 9,186E-03 ! glycerolipid catabolic process GO:0046503 14 8 1,000 3,497E-04 9,089E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,497E-04 8,993E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 3,497E-04 8,899E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 3,497E-04 8,807E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 3,497E-04 8,718E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 1,000 3,497E-04 8,63E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 3,497E-04 8,543E-03 ! regulation of cell morphogenesis GO:0022604 243 93 3,000 3,549E-04 8,585E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 3,549E-04 8,501E-03 ! regulation of hormone secretion GO:0046883 69 41 2,000 4,3E-04 0,01019878 ! mesenchymal cell development GO:0014031 94 41 2,000 4,3E-04 0,01010072 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 4,486E-04 0,01043663 ! neutral lipid catabolic process GO:0046461 14 9 1,000 4,486E-04 0,01033817 ! induction of positive chemotaxis GO:0050930 17 9 1,000 4,486E-04 0,01024155 ! regulation of glycolysis GO:0006110 20 9 1,000 4,486E-04 0,01014672 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 4,486E-04 0,01005363 ! renal water homeostasis GO:0003091 15 9 1,000 4,486E-04 9,962E-03 ! skeletal muscle tissue development GO:0007519 223 100 3,000 4,676E-04 0,01029115 GO:0060538|skeletal muscle organ development, ! regulation of developmental growth GO:0048638 16 10 1,000 5,594E-04 0,0122018 ! lung alveolus development GO:0048286 26 10 1,000 5,594E-04 0,01209382 ! motor axon guidance GO:0008045 22 10 1,000 5,594E-04 0,01198773 ! regulation of bone resorption GO:0045124 25 10 1,000 5,594E-04 0,01188349 ! protein heterooligomerization GO:0051291 17 10 1,000 5,594E-04 0,01178105 ! positive regulation of phagocytosis GO:0050766 14 10 1,000 5,594E-04 0,01168036 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 1,000 5,594E-04 0,01158137 ! multicellular organismal water homeostasis GO:0050891 16 10 1,000 5,594E-04 0,01148405 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 5,594E-04 0,01138835 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 5,594E-04 0,01129423 ! response to insulin stimulus GO:0032868 98 47 2,000 6,439E-04 0,01289439 ! cortical actin cytoskeleton organization GO:0030866 29 11 1,000 6,821E-04 0,01354783 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 6,821E-04 0,01343858 ! blood vessel remodeling GO:0001974 30 11 1,000 6,821E-04 0,01333107 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 6,821E-04 0,01322526 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 6,821E-04 0,01312113 ! DNA methylation GO:0006306 19 11 1,000 6,821E-04 0,01301862 GO:0006305|DNA alkylation, ! apical protein localization GO:0045176 18 11 1,000 6,821E-04 0,0129177 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 6,821E-04 0,01281833 ! germ cell migration GO:0008354 26 11 1,000 6,821E-04 0,01272048 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 1,000 6,821E-04 0,01262412 ! sequestering of metal ion GO:0051238 15 11 1,000 6,821E-04 0,0125292 ! regulation of embryonic development GO:0045995 35 11 1,000 6,821E-04 0,0124357 ! positive regulation of cell cycle GO:0045787 96 48 2,000 6,851E-04 0,01239725 ! vascular process in circulatory system GO:0003018 85 48 2,000 6,851E-04 0,0123061 ! activation of caspase activity GO:0006919 95 50 2,000 7,723E-04 0,01377176 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 8,166E-04 0,0144564 ! cortical cytoskeleton organization GO:0030865 30 12 1,000 8,166E-04 0,0143524 ! virus-host interaction GO:0019048 30 12 1,000 8,166E-04 0,01424988 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 8,166E-04 0,01414882 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 8,166E-04 0,01404918 ! T cell proliferation GO:0042098 32 12 1,000 8,166E-04 0,01395093 ! entry into host cell GO:0030260 34 12 1,000 8,166E-04 0,01385405 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 17 12 1,000 8,166E-04 0,0137585 ! histone acetylation GO:0016573 27 12 1,000 8,166E-04 0,01366427 ! peptidyl-lysine modification GO:0018205 21 12 1,000 8,166E-04 0,01357131 ! regulation of leukocyte migration GO:0002685 29 12 1,000 8,166E-04 0,01347962 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 8,166E-04 0,01338915 ! localization within membrane GO:0051668 26 12 1,000 8,166E-04 0,01329989 ! regulation of cell projection organization GO:0031344 135 51 2,000 8,184E-04 0,01324135 ! viral infectious cycle GO:0019058 104 51 2,000 8,184E-04 0,01315424 ! DNA-dependent DNA replication GO:0006261 82 52 2,000 8,663E-04 0,01383234 ! Notch signaling pathway GO:0007219 111 52 2,000 8,663E-04 0,01374252 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 9,628E-04 0,01517545 ! asymmetric protein localization GO:0008105 24 13 1,000 9,628E-04 0,01507817 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 9,628E-04 0,01498213 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 9,628E-04 0,01488731 ! regulation of mRNA stability GO:0043488 32 13 1,000 9,628E-04 0,01479368 ! activation of phospholipase C activity GO:0007202 110 54 2,000 9,672E-04 0,01476857 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 2,000 1,02E-03 0,01548328 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 2,000 1,02E-03 0,0153877 ! response to UV GO:0009411 120 55 2,000 1,02E-03 0,0152933 ! skeletal muscle fiber development GO:0048741 130 56 2,000 1,075E-03 0,01601874 ! regulation of DNA replication GO:0006275 105 56 2,000 1,075E-03 0,01592166 ! regulation of RNA stability GO:0043487 33 14 1,000 1,121E-03 0,01649284 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 1,121E-03 0,01639408 GO:0060675|ureteric bud morphogenesis, ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 1,132E-03 0,01646325 ! positive regulation of caspase activity GO:0043280 108 57 2,000 1,132E-03 0,01636583 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 2,000 1,132E-03 0,01626956 ! regulation of phospholipase activity GO:0010517 113 57 2,000 1,132E-03 0,01617442 ! aging GO:0007568 112 58 2,000 1,191E-03 0,01691349 ! positive regulation of lipase activity GO:0060193 115 58 2,000 1,191E-03 0,01681573 ! establishment of organelle localization GO:0051656 122 59 2,000 1,251E-03 0,01756905 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 1,29E-03 0,01800932 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 1,29E-03 0,017907 ! regulation of vasodilation GO:0042312 27 15 1,000 1,29E-03 0,01780583 ! water homeostasis GO:0030104 28 15 1,000 1,29E-03 0,01770579 ! positive regulation of secretion GO:0051047 110 61 2,000 1,378E-03 0,01880906 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,471E-03 0,01996361 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 1,471E-03 0,01985331 ! DNA replication initiation GO:0006270 28 16 1,000 1,471E-03 0,01974423 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 1,471E-03 0,01963634 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,471E-03 0,01952962 ! regulation of protein complex assembly GO:0043254 132 63 2,000 1,513E-03 0,01997663 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 1,583E-03 0,02079237 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 1,583E-03 0,02068118 ! nucleoside monophosphate metabolic process GO:0009123 117 65 2,000 1,655E-03 0,02151066 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 1,663E-03 0,02149769 ! DNA unwinding during replication GO:0006268 26 17 1,000 1,663E-03 0,02138455 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 1,663E-03 0,02127259 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 1,73E-03 0,02200832 ! activation of MAPK activity GO:0000187 124 67 2,000 1,806E-03 0,02286119 ! myeloid cell differentiation GO:0030099 126 67 2,000 1,806E-03 0,02274335 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 1,867E-03 0,02338602 ! regulation of lipase activity GO:0060191 137 68 2,000 1,885E-03 0,02348925 ! cell projection assembly GO:0030031 138 68 2,000 1,885E-03 0,02337002 ! lung development GO:0030324 165 69 2,000 1,965E-03 0,02424593 ! protein maturation by peptide bond cleavage GO:0051605 118 70 2,000 2,048E-03 0,025139 ! neuron maturation GO:0042551 46 19 1,000 2,081E-03 0,02542439 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 2,081E-03 0,0252979 ! protein export from nucleus GO:0006611 40 19 1,000 2,081E-03 0,02517267 ! cellular pigmentation GO:0033059 37 19 1,000 2,081E-03 0,02504866 ! respiratory tube development GO:0030323 171 72 2,000 2,22E-03 0,02657982 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 2,307E-03 0,027496 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 2,307E-03 0,02736252 ! protein amino acid acetylation GO:0006473 41 20 1,000 2,307E-03 0,02723034 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 2,307E-03 0,02709942 ! transcription from RNA polymerase III promoter GO:0006383 46 20 1,000 2,307E-03 0,02696976 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 2,307E-03 0,02684133 GO:0010675|regulation of cellular carbohydrate metabolic process, ! DNA duplex unwinding GO:0032508 30 20 1,000 2,307E-03 0,02671412 GO:0032392|DNA geometric change, ! body fluid secretion GO:0007589 33 20 1,000 2,307E-03 0,02658811 ! negative regulation of translation GO:0017148 32 20 1,000 2,307E-03 0,02646329 ! respiratory system development GO:0060541 175 74 2,000 2,4E-03 0,0273978 ! organelle localization GO:0051640 155 74 2,000 2,4E-03 0,02727036 ! lipid phosphorylation GO:0046834 43 21 1,000 2,544E-03 0,02877537 ! plasma membrane fusion GO:0045026 33 21 1,000 2,544E-03 0,02864276 ! cell-matrix adhesion GO:0007160 181 76 2,000 2,589E-03 0,02901631 ! ureteric bud development GO:0001657 50 22 1,000 2,792E-03 0,03114649 ! cell aging GO:0007569 48 22 1,000 2,792E-03 0,03100491 ! renal system process GO:0003014 42 22 1,000 2,792E-03 0,03086462 ! positive regulation of locomotion GO:0040017 44 22 1,000 2,792E-03 0,03072559 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of intracellular transport GO:0032388 42 22 1,000 2,792E-03 0,0305878 ! protein stabilization GO:0050821 41 22 1,000 2,792E-03 0,03045125 ! blood coagulation GO:0007596 151 79 2,000 2,89E-03 0,03137964 GO:0050817|coagulation, ! protein oligomerization GO:0051259 149 79 2,000 2,89E-03 0,03124079 ! regulation of chemotaxis GO:0050920 45 23 1,000 3,051E-03 0,03283386 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 3,051E-03 0,03268986 ! DNA modification GO:0006304 36 23 1,000 3,051E-03 0,03254711 ! muscle cell differentiation GO:0042692 178 81 2,000 3,102E-03 0,03294912 ! cell-substrate adhesion GO:0031589 189 82 2,000 3,212E-03 0,03396429 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 3,32E-03 0,03496511 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 3,32E-03 0,03481504 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 3,32E-03 0,03466626 ! sex determination GO:0007530 48 24 1,000 3,32E-03 0,03451874 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 3,32E-03 0,03437248 ! response to nutrient GO:0007584 135 84 2,000 3,438E-03 0,03543408 ! hemostasis GO:0007599 165 85 2,000 3,554E-03 0,03648163 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 3,554E-03 0,03632899 ! vasculogenesis GO:0001570 49 25 1,000 3,601E-03 0,03665308 ! regulation of behavior GO:0050795 48 25 1,000 3,601E-03 0,03650099 ! lymphocyte proliferation GO:0046651 55 25 1,000 3,601E-03 0,03635016 ! protein tetramerization GO:0051262 57 25 1,000 3,601E-03 0,03620057 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 3,892E-03 0,03896556 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 3,892E-03 0,03880652 ! regulation of cell cycle process GO:0010564 161 90 2,000 4,173E-03 0,04144201 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 4,193E-03 0,04147485 ! cellular response to oxidative stress GO:0034599 43 27 1,000 4,193E-03 0,04130762 ! leukocyte proliferation GO:0070661 59 27 1,000 4,193E-03 0,04114172 GO:0032943|mononuclear cell proliferation, ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 4,505E-03 0,04402649 ! protein amino acid acylation GO:0043543 59 28 1,000 4,505E-03 0,04385108 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 4,505E-03 0,04367707 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 4,828E-03 0,04661821 ! somitogenesis GO:0001756 52 29 1,000 4,828E-03 0,04643467 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 4,828E-03 0,04625258 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 5,143E-03 0,04908347 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 5,161E-03 0,04905625 ! leukocyte differentiation GO:0002521 232 98 2,000 5,292E-03 0,05011145 ! metanephros development GO:0001656 81 32 1,000 5,857E-03 0,05524553 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 5,857E-03 0,05503305 ! positive regulation of catabolic process GO:0009896 72 32 1,000 5,857E-03 0,0548222 ! triglyceride metabolic process GO:0006641 46 33 1,000 6,22E-03 0,05800118 ! positive regulation of endocytosis GO:0045807 56 35 1,000 6,977E-03 0,06481033 ! calcium-mediated signaling GO:0019722 67 35 1,000 6,977E-03 0,06456483 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 7,37E-03 0,06794656 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 7,773E-03 0,07139298 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 7,773E-03 0,07112559 ! tissue remodeling GO:0048771 78 37 1,000 7,773E-03 0,07086019 ! neutral lipid metabolic process GO:0006638 54 38 1,000 8,186E-03 0,07434578 GO:0006639|acylglycerol metabolic process, ! regulation of protein stability GO:0031647 77 38 1,000 8,186E-03 0,07407043 ! glycerol ether metabolic process GO:0006662 57 40 1,000 9,041E-03 0,08150049 ! Rho protein signal transduction GO:0007266 88 40 1,000 9,041E-03 0,08120085 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 1,000 9,482E-03 0,08485498 ! organic ether metabolic process GO:0018904 59 42 1,000 9,933E-03 0,08856665 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 9,933E-03 0,08824459 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01039379 0,09200006 GO:0090047|positive regulation of transcription regulator activity, ! segmentation GO:0035282 78 43 1,000 0,01039379 0,09166793 ! neuron migration GO:0001764 85 43 1,000 0,01039379 0,09133819 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,01086349 0,09512364 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,01086349 0,09478392 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,01134242 0,09861042 ! biopolymer methylation GO:0043414 91 45 1,000 0,01134242 0,09826073 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 0,01183051 0,10212698 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,01183051 0,10176738 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,01183051 0,1014103 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,01183051 0,10105572 ! pigmentation GO:0043473 103 46 1,000 0,01183051 0,10070361 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,01183051 0,10035394 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01283389 0,10848857 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,01283389 0,10811448 ! methylation GO:0032259 97 48 1,000 0,01283389 0,10774295 ! response to calcium ion GO:0051592 94 49 1,000 0,01334904 0,11168394 ! protein homooligomerization GO:0051260 84 49 1,000 0,01334904 0,11130277 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,01387307 0,11527863 ! positive regulation of binding GO:0051099 88 52 1,000 0,0149475 0,12378557 ! excretion GO:0007588 87 52 1,000 0,0149475 0,12336738 ! histone modification GO:0016570 104 52 1,000 0,0149475 0,122952 ! amino acid activation GO:0043038 98 52 1,000 0,0149475 0,12253941 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of growth GO:0045927 96 53 1,000 0,01549776 0,12662551 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,01549776 0,12620343 ! regulation of translational initiation GO:0006446 87 54 1,000 0,01605663 0,13032006 ! membrane fusion GO:0006944 122 54 1,000 0,01605663 0,12988854 ! covalent chromatin modification GO:0016569 115 54 1,000 0,01605663 0,12945986 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,01605663 0,12903401 ! cell maturation GO:0048469 107 55 1,000 0,01662403 0,13315577 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,01662403 0,13272062 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01773896 0,14116053 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01773896 0,14070222 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01773896 0,14024687 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01773896 0,13979446 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01773896 0,13934496 ! neuron fate determination GO:0048664 7 5 0,000 0,01773896 0,13889834 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01773896 0,13845458 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01773896 0,13801364 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01773896 0,1375755 ! polyol transport GO:0015791 12 5 0,000 0,01773896 0,13714014 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01773896 0,13670752 ! response to superoxide GO:0000303 10 5 0,000 0,01773896 0,13627762 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01773896 0,13585042 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01773896 0,13542589 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01773896 0,135004 ! female meiosis GO:0007143 10 5 0,000 0,01773896 0,13458473 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01773896 0,13416806 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01773896 0,13375396 ! hypothalamus development GO:0021854 9 5 0,000 0,01773896 0,13334241 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01773896 0,13293338 ! cobalt ion transport GO:0006824 11 5 0,000 0,01773896 0,13252686 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01773896 0,13212282 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01773896 0,13172123 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01773896 0,13132207 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01773896 0,13092533 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01773896 0,13053097 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01773896 0,13013899 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01773896 0,12974935 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01773896 0,12936204 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01773896 0,12897703 ! transposition GO:0032196 9 5 0,000 0,01773896 0,12859431 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01773896 0,12821386 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01773896 0,12783564 ! negative chemotaxis GO:0050919 16 5 0,000 0,01773896 0,12745966 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01773896 0,12708588 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01773896 0,12671428 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01773896 0,12634485 ! behavioral response to pain GO:0048266 10 5 0,000 0,01773896 0,12597757 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01773896 0,12561242 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01773896 0,12524937 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01773896 0,12488842 ! micturition GO:0060073 9 5 0,000 0,01773896 0,12452955 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01773896 0,12417273 ! copulation GO:0007620 9 5 0,000 0,01773896 0,12381795 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01773896 0,12346519 ! bioluminescence GO:0008218 9 5 0,000 0,01773896 0,12311444 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01773896 0,12276568 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01773896 0,12241888 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01773896 0,12207404 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01773896 0,12173113 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01773896 0,12139015 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01773896 0,12105107 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01773896 0,12071388 ! grooming behavior GO:0007625 6 5 0,000 0,01773896 0,12037856 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01773896 0,12004511 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01773896 0,11971349 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01773896 0,1193837 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01773896 0,11905572 ! response to protozoan GO:0001562 13 5 0,000 0,01773896 0,11872954 ! lymph vessel development GO:0001945 10 5 0,000 0,01773896 0,11840515 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01773896 0,11808252 ! endochondral ossification GO:0001958 17 5 0,000 0,01773896 0,11776164 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01773896 0,1174425 ! single strand break repair GO:0000012 8 5 0,000 0,01773896 0,11712509 ! parathyroid gland development GO:0060017 14 5 0,000 0,01773896 0,11680939 ! anagen GO:0042640 7 5 0,000 0,01773896 0,11649539 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01773896 0,11618307 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01773896 0,11587242 ! cytokine secretion GO:0050663 15 5 0,000 0,01773896 0,11556342 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01773896 0,11525607 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01773896 0,11495035 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01773896 0,11464625 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01773896 0,11434376 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01773896 0,11404285 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01773896 0,11374353 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01773896 0,11344577 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01773896 0,11314956 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01773896 0,1128549 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01773896 0,11256178 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01773896 0,11227016 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01773896 0,11198006 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01773896 0,11169145 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01773896 0,11140433 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01773896 0,11111868 ! microvillus organization GO:0032528 8 5 0,000 0,01773896 0,11083448 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01773896 0,11055174 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01773896 0,11027044 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01773896 0,10999057 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01773896 0,10971211 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01773896 0,10943506 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01773896 0,1091594 ! polyol catabolic process GO:0046174 9 5 0,000 0,01773896 0,10888513 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01773896 0,10861224 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01773896 0,10834071 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01773896 0,10807053 ! muscle cell migration GO:0014812 8 5 0,000 0,01773896 0,1078017 ! mitochondrial fission GO:0000266 8 5 0,000 0,01773896 0,1075342 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01773896 0,10726803 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01773896 0,10700317 ! mRNA transcription GO:0009299 10 5 0,000 0,01773896 0,10673961 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01773896 0,10647735 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01773896 0,10621638 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01773896 0,10595668 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01773896 0,10569825 ! monocyte activation GO:0042117 10 5 0,000 0,01773896 0,10544108 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01773896 0,10518515 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01773896 0,10493047 ! response to food GO:0032094 6 5 0,000 0,01773896 0,10467701 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01773896 0,10442478 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01773896 0,10417376 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01773896 0,10392394 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01773896 0,10367532 ! forebrain neuron development GO:0021884 13 5 0,000 0,01773896 0,10342788 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01773896 0,10318163 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01773896 0,10293654 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01773896 0,10269261 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01773896 0,10244984 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01773896 0,10220822 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01773896 0,10196773 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01773896 0,10172836 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01773896 0,10149013 ! lipid glycosylation GO:0030259 7 5 0,000 0,01773896 0,101253 ! nucleobase transport GO:0015851 6 5 0,000 0,01773896 0,10101698 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01773896 0,10078205 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01773896 0,10054822 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01773896 0,10031547 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01773896 0,1000838 ! basic amino acid transport GO:0015802 12 5 0,000 0,01773896 0,09985319 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01773896 0,09962364 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01773896 0,09939515 ! actin nucleation GO:0045010 11 5 0,000 0,01773896 0,0991677 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01773896 0,09894129 ! depurination GO:0045007 5 5 0,000 0,01773896 0,09871591 ! depyrimidination GO:0045008 10 5 0,000 0,01773896 0,09849155 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01773896 0,09826822 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01773896 0,09804589 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01773896 0,09782457 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01773896 0,09760424 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01773896 0,09738491 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01773896 0,09716655 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01773896 0,09694918 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01773896 0,09673278 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01773896 0,09651733 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01773896 0,09630285 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01773896 0,09608932 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01773896 0,09587673 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01773896 0,09566508 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01773896 0,09545437 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01773896 0,09524458 ! response to arsenic GO:0046685 11 5 0,000 0,01773896 0,09503571 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01773896 0,09482775 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01773896 0,09462071 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01773896 0,09441456 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01773896 0,09420931 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01773896 0,09400495 ! response to mercury ion GO:0046689 8 5 0,000 0,01773896 0,09380148 ! response to cadmium ion GO:0046686 7 5 0,000 0,01773896 0,09359888 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01773896 0,09339716 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01773896 0,09319631 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01773896 0,09299632 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01773896 0,09279718 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01773896 0,0925989 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01773896 0,09240146 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01773896 0,09220486 ! decidualization GO:0046697 11 5 0,000 0,01773896 0,09200909 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01773896 0,09181416 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01773896 0,09162005 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01773896 0,09142676 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01773896 0,09123428 ! embryonic cleavage GO:0040016 6 5 0,000 0,01773896 0,09104261 ! peroxisome fission GO:0016559 5 5 0,000 0,01773896 0,09085175 ! histone demethylation GO:0016577 13 5 0,000 0,01773896 0,09066168 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01773896 0,09047241 ! mitotic recombination GO:0006312 9 5 0,000 0,01773896 0,09028392 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01773896 0,09009622 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01773896 0,0899093 ! metaphase plate congression GO:0051310 7 5 0,000 0,01773896 0,08972315 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01773896 0,08953778 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01773896 0,08935316 ! enteric nervous system development GO:0048484 8 5 0,000 0,01773896 0,08916931 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01773896 0,08898621 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01773896 0,08880386 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01773896 0,08862226 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01773896 0,08844139 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01773896 0,08826127 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01773896 0,08808188 ! B cell homeostasis GO:0001782 13 5 0,000 0,01773896 0,08790321 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01773896 0,08772527 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01773896 0,08754805 ! metaphase GO:0051323 11 5 0,000 0,01773896 0,08737154 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01773896 0,08719574 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01773896 0,08702065 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01773896 0,08684626 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01773896 0,08667257 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01773896 0,08649957 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01773896 0,08632726 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01773896 0,08615563 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01773896 0,08598469 ! response to redox state GO:0051775 6 5 0,000 0,01773896 0,08581442 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01773896 0,08564483 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01773896 0,0854759 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01773896 0,08530764 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01773896 0,08514005 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01773896 0,0849731 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01773896 0,08480682 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01773896 0,08464118 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01773896 0,08447619 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01773896 0,08431184 ! striatum development GO:0021756 14 5 0,000 0,01773896 0,08414812 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01773896 0,08398505 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01773896 0,0838226 ! glial cell migration GO:0008347 10 5 0,000 0,01773896 0,08366078 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01773896 0,08349958 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01773896 0,08333901 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01773896 0,08317905 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01773896 0,0830197 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01773896 0,08286096 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01773896 0,08270283 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01773896 0,0825453 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01773896 0,08238837 ! neuroprotection GO:0043526 8 5 0,000 0,01773896 0,08223204 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01773896 0,08207629 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01773896 0,08192114 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01773896 0,08176657 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01773896 0,08161259 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01773896 0,08145918 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01773896 0,08130635 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01773896 0,08115409 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01773896 0,0810024 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01773896 0,08085127 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01773896 0,08070071 ! spindle assembly GO:0051225 6 5 0,000 0,01773896 0,08055071 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01773896 0,08040127 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01773896 0,08025238 ! protein palmitoylation GO:0018345 12 5 0,000 0,01773896 0,08010404 ! drug metabolic process GO:0017144 7 5 0,000 0,01773896 0,07995624 ! stem cell division GO:0017145 11 5 0,000 0,01773896 0,07980899 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01773896 0,07966229 ! organ regeneration GO:0031100 7 5 0,000 0,01773896 0,07951612 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01773896 0,07937048 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01773896 0,07922538 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,01778419 0,07928244 ! heart morphogenesis GO:0003007 105 57 1,000 0,01778419 0,07913803 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,01778419 0,07899414 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,01837681 0,08147832 ! maintenance of location GO:0051235 124 58 1,000 0,01837681 0,08133071 ! nuclear export GO:0051168 110 59 1,000 0,01897771 0,08383822 ! lipid modification GO:0030258 112 60 1,000 0,01958681 0,08637287 ! regulation of endocytosis GO:0030100 104 60 1,000 0,01958681 0,08621724 ! kidney development GO:0001822 133 60 1,000 0,01958681 0,08606218 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 0,02020405 0,08861489 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,02082937 0,09119381 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02124911 0,09286507 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02124911 0,09269924 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02124911 0,092534 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02124911 0,09236935 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02124911 0,09220528 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02124911 0,0920418 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02124911 0,09187889 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02124911 0,09171656 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02124911 0,09155481 ! response to oxygen radical GO:0000305 11 6 0,000 0,02124911 0,09139362 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02124911 0,091233 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02124911 0,09107294 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02124911 0,09091344 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02124911 0,0907545 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02124911 0,09059612 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02124911 0,09043828 ! forebrain regionalization GO:0021871 9 6 0,000 0,02124911 0,090281 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02124911 0,09012426 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02124911 0,08996807 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02124911 0,08981241 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02124911 0,0896573 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02124911 0,08950272 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02124911 0,08934867 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02124911 0,08919515 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02124911 0,08904215 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02124911 0,08888968 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02124911 0,08873774 ! malate metabolic process GO:0006108 13 6 0,000 0,02124911 0,08858631 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02124911 0,08843539 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02124911 0,08828499 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02124911 0,0881351 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02124911 0,08798572 ! protein refolding GO:0042026 15 6 0,000 0,02124911 0,08783684 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02124911 0,08768847 ! opsonization GO:0008228 8 6 0,000 0,02124911 0,0875406 ! mating behavior GO:0007617 7 6 0,000 0,02124911 0,08739322 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02124911 0,08724634 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02124911 0,08709996 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02124911 0,08695406 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02124911 0,08680865 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02124911 0,08666373 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02124911 0,08651929 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02124911 0,08637533 ! toxin metabolic process GO:0009404 11 6 0,000 0,02124911 0,08623185 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02124911 0,08608885 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02124911 0,08594632 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02124911 0,08580426 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02124911 0,08566267 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02124911 0,08552154 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02124911 0,08538088 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02124911 0,08524068 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02124911 0,08510094 ! thymic T cell selection GO:0045061 16 6 0,000 0,02124911 0,08496166 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02124911 0,08482284 ! protein lipoylation GO:0009249 10 6 0,000 0,02124911 0,08468446 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02124911 0,08454654 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02124911 0,08440907 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02124911 0,08427204 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02124911 0,08413545 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02124911 0,08399931 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02124911 0,08386361 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02124911 0,08372835 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02124911 0,08359352 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02124911 0,08345912 ! hyperosmotic response GO:0006972 10 6 0,000 0,02124911 0,08332516 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02124911 0,08319163 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02124911 0,08305852 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02124911 0,08292584 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02124911 0,08279358 ! urea metabolic process GO:0019627 7 6 0,000 0,02124911 0,08266174 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02124911 0,08253033 ! neutrophil activation GO:0042119 7 6 0,000 0,02124911 0,08239933 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02124911 0,08226874 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02124911 0,08213857 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02124911 0,08200881 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02124911 0,08187946 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02124911 0,08175051 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02124911 0,08162197 ! neuron apoptosis GO:0051402 15 6 0,000 0,02124911 0,08149384 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02124911 0,08136611 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02124911 0,08123877 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02124911 0,08111184 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02124911 0,0809853 ! carnitine transport GO:0015879 10 6 0,000 0,02124911 0,08085915 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02124911 0,0807334 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02124911 0,08060804 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02124911 0,08048306 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02124911 0,08035848 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02124911 0,08023427 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02124911 0,08011046 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02124911 0,07998702 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02124911 0,07986396 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02124911 0,07974128 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02124911 0,07961898 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02124911 0,07949705 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02124911 0,0793755 ! response to UV-C GO:0010225 14 6 0,000 0,02124911 0,07925431 ! astrocyte development GO:0014002 16 6 0,000 0,02124911 0,0791335 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02124911 0,07901305 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02124911 0,07889297 ! interaction with symbiont GO:0051702 14 6 0,000 0,02124911 0,07877326 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02124911 0,0786539 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02124911 0,07853491 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02124911 0,07841628 ! response to copper ion GO:0046688 10 6 0,000 0,02124911 0,078298 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02124911 0,07818008 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02124911 0,07806252 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02124911 0,07794531 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02124911 0,07782845 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02124911 0,07771194 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02124911 0,07759578 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02124911 0,07747996 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02124911 0,07736449 ! hair follicle maturation GO:0048820 8 6 0,000 0,02124911 0,07724937 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02124911 0,07713458 ! Schwann cell development GO:0014044 15 6 0,000 0,02124911 0,07702014 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02124911 0,07690604 ! response to pheromone GO:0019236 6 6 0,000 0,02124911 0,07679227 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02124911 0,07667884 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02124911 0,07656574 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02124911 0,07645298 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02124911 0,07634055 ! subpallium development GO:0021544 15 6 0,000 0,02124911 0,07622845 ! neural tube patterning GO:0021532 8 6 0,000 0,02124911 0,07611668 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02124911 0,07600523 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02124911 0,07589412 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02124911 0,07578332 ! G2 phase GO:0051319 16 6 0,000 0,02124911 0,07567285 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02124911 0,0755627 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02124911 0,07545287 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02124911 0,07534336 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02124911 0,07523417 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02124911 0,07512529 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02124911 0,07501673 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02124911 0,07490848 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02124911 0,07480054 ! receptor internalization GO:0031623 11 6 0,000 0,02124911 0,07469291 ! plasminogen activation GO:0031639 9 6 0,000 0,02124911 0,0745856 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02124911 0,07447859 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02124911 0,07437188 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02124911 0,07426549 ! protein deubiquitination GO:0016579 16 6 0,000 0,02124911 0,07415939 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02124911 0,0740536 ! protein destabilization GO:0031648 9 6 0,000 0,02124911 0,07394811 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02124911 0,07384292 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02124911 0,07373803 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02124911 0,07363344 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02124911 0,07352914 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02124911 0,07342514 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02124911 0,07332143 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02124911 0,07321802 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02124911 0,07311489 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02124911 0,07301206 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02124911 0,07290952 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02124911 0,07280726 ! neural plate development GO:0001840 9 6 0,000 0,02124911 0,07270529 ! catecholamine transport GO:0051937 9 6 0,000 0,02124911 0,0726036 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02124911 0,0725022 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02124911 0,07240108 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02124911 0,07230024 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02124911 0,07219969 ! maternal placenta development GO:0001893 12 6 0,000 0,02124911 0,07209941 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02124911 0,07199941 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02124911 0,07189969 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02124911 0,07180024 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02124911 0,07170107 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02124911 0,07160217 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02124911 0,07150355 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02124911 0,07140519 GO:0055081|anion homeostasis, ! regulation of mitosis GO:0007088 112 63 1,000 0,0214627 0,07202387 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 1,000 0,0214627 0,07192507 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,02210398 0,07397263 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,02407487 0,08045814 ! chromosome segregation GO:0007059 127 67 1,000 0,02407487 0,08034822 ! tRNA transcription GO:0009304 17 7 0,000 0,02474681 0,08247812 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02474681 0,08236575 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02474681 0,08225369 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02474681 0,08214193 ! regulation of helicase activity GO:0051095 16 7 0,000 0,02474681 0,08203048 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02474681 0,08191933 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02474681 0,08180848 ! sleep GO:0030431 16 7 0,000 0,02474681 0,08169792 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02474681 0,08158767 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02474681 0,08147771 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02474681 0,08136805 ! prostate gland development GO:0030850 14 7 0,000 0,02474681 0,08125869 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02474681 0,08114961 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02474681 0,08104084 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02474681 0,08093235 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02474681 0,08082415 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02474681 0,08071624 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02474681 0,08060862 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02474681 0,08050128 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02474681 0,08039423 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02474681 0,08028747 ! glycolipid transport GO:0046836 11 7 0,000 0,02474681 0,08018099 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02474681 0,08007479 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02474681 0,07996887 ! neuron adhesion GO:0007158 14 7 0,000 0,02474681 0,07986323 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02474681 0,07975787 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02474681 0,07965278 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02474681 0,07954798 ! pericardium development GO:0060039 16 7 0,000 0,02474681 0,07944345 ! fibril organization GO:0043206 17 7 0,000 0,02474681 0,07933919 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02474681 0,07923521 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02474681 0,0791315 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02474681 0,07902806 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02474681 0,07892489 ! lipoprotein transport GO:0042953 14 7 0,000 0,02474681 0,07882199 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02474681 0,07871935 ! rhythmic behavior GO:0007622 17 7 0,000 0,02474681 0,07861699 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02474681 0,07851489 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02474681 0,07841305 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02474681 0,07831148 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02474681 0,07821017 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02474681 0,07810913 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02474681 0,07800834 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02474681 0,07790781 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02474681 0,07780755 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02474681 0,07770754 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02474681 0,07760778 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02474681 0,07750829 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02474681 0,07740904 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02474681 0,07731006 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02474681 0,07721132 ! spinal cord patterning GO:0021511 14 7 0,000 0,02474681 0,07711284 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02474681 0,0770146 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02474681 0,07691662 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02474681 0,07681889 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02474681 0,0767214 ! adrenal gland development GO:0030325 17 7 0,000 0,02474681 0,07662416 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02474681 0,07652717 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02474681 0,07643042 ! ovulation GO:0030728 10 7 0,000 0,02474681 0,07633392 ! adenohypophysis development GO:0021984 11 7 0,000 0,02474681 0,07623766 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02474681 0,07614164 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02474681 0,07604587 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02474681 0,07595033 ! microtubule nucleation GO:0007020 21 7 0,000 0,02474681 0,07585504 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02474681 0,07575998 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02474681 0,07566516 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02474681 0,07557058 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02474681 0,07547623 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02474681 0,07538212 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02474681 0,07528825 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02474681 0,07519461 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02474681 0,0751012 ! galactose metabolic process GO:0006012 13 7 0,000 0,02474681 0,07500802 ! vesicle fusion GO:0006906 20 7 0,000 0,02474681 0,07491507 ! response to dietary excess GO:0002021 8 7 0,000 0,02474681 0,07482236 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02474681 0,07472987 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02474681 0,07463761 GO:0045851|pH reduction, ! melanosome organization GO:0032438 10 7 0,000 0,02474681 0,07454558 ! organ growth GO:0035265 15 7 0,000 0,02474681 0,07445377 ! nucleoside transport GO:0015858 11 7 0,000 0,02474681 0,07436219 ! nucleoside salvage GO:0043174 11 7 0,000 0,02474681 0,07427084 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02474681 0,07417971 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02474681 0,0740888 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02474681 0,07399812 ! parturition GO:0007567 16 7 0,000 0,02474681 0,07390766 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02474681 0,07381742 ! rRNA modification GO:0000154 14 7 0,000 0,02474681 0,07372739 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02474681 0,07363759 ! spindle checkpoint GO:0031577 16 7 0,000 0,02474681 0,07354801 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02474681 0,07345864 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02474681 0,07336949 ! monocyte differentiation GO:0030224 16 7 0,000 0,02474681 0,07328056 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02474681 0,07319184 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02474681 0,07310334 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02474681 0,07301505 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02474681 0,07292698 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,02474681 0,07283911 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02474681 0,07275146 ! fibrinolysis GO:0042730 11 7 0,000 0,02474681 0,07266402 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02474681 0,07257679 ! eating behavior GO:0042755 8 7 0,000 0,02474681 0,07248976 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02474681 0,07240295 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02474681 0,07231634 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02474681 0,07222994 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02474681 0,07214375 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02474681 0,07205776 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02474681 0,07197198 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02474681 0,0718864 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02474681 0,07180103 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02474681 0,07171585 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02474681 0,07163088 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02474681 0,07154611 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02474681 0,07146154 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02474681 0,07137717 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02474681 0,071293 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02474681 0,07120903 ! histone ubiquitination GO:0016574 9 7 0,000 0,02474681 0,07112525 ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02474681 0,07104167 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02474681 0,07095829 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02474681 0,0708751 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02474681 0,07079211 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02474681 0,07070931 ! transcription termination GO:0006353 14 7 0,000 0,02474681 0,07062671 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02474681 0,0705443 ! anaphase GO:0051322 18 7 0,000 0,02474681 0,07046208 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02474681 0,07038005 ! axonal fasciculation GO:0007413 19 7 0,000 0,02474681 0,07029821 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02474681 0,07021657 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02474681 0,07013511 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02474681 0,07005384 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02474681 0,06997276 ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02474681 0,06989186 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02474681 0,06981116 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02474681 0,06973064 ! antibiotic transport GO:0042891 9 7 0,000 0,02474681 0,0696503 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02474681 0,06957015 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02474681 0,06949019 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02474681 0,06941041 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02474681 0,06933081 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02474681 0,06925139 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02474681 0,06917215 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02474681 0,0690931 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02474681 0,06901423 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02474681 0,06893553 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02474681 0,06885702 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02474681 0,06877868 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02474681 0,06870053 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02474681 0,06862255 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02474681 0,06854474 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02474681 0,06846712 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02474681 0,06838966 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02474681 0,06831239 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02474681 0,06823529 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02474681 0,06815836 ! muscle adaptation GO:0043500 13 7 0,000 0,02474681 0,0680816 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02474681 0,06800502 ! retina homeostasis GO:0001895 12 7 0,000 0,02474681 0,06792861 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02474681 0,06785237 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02474681 0,0677763 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02474681 0,06770041 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02474681 0,06762468 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,0247473 0,06755045 ! adaptive immune response GO:0002250 126 68 1,000 0,0247473 0,06747506 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell size GO:0045792 144 69 1,000 0,02542737 0,06925202 ! urogenital system development GO:0001655 149 69 1,000 0,02542737 0,0691749 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,02542737 0,06909795 ! developmental maturation GO:0021700 128 69 1,000 0,02542737 0,06902118 ! germ cell development GO:0007281 133 70 1,000 0,026115 0,07080905 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,02681015 0,07261329 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,02681015 0,07253288 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02823211 0,07629541 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02823211 0,07621111 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02823211 0,07612699 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02823211 0,07604306 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02823211 0,07595931 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02823211 0,07587575 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02823211 0,07579237 ! male meiosis GO:0007140 9 8 0,000 0,02823211 0,07570917 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02823211 0,07562616 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02823211 0,07554332 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02823211 0,07546067 ! meiotic prophase I GO:0007128 14 8 0,000 0,02823211 0,0753782 ! response to zinc ion GO:0010043 12 8 0,000 0,02823211 0,07529591 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02823211 0,0752138 ! oligopeptide transport GO:0006857 16 8 0,000 0,02823211 0,07513187 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02823211 0,07505011 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02823211 0,07496854 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02823211 0,07488714 ! signal peptide processing GO:0006465 12 8 0,000 0,02823211 0,07480592 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02823211 0,07472487 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02823211 0,074644 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02823211 0,0745633 ! succinate metabolic process GO:0006105 17 8 0,000 0,02823211 0,07448278 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02823211 0,07440243 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02823211 0,07432226 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02823211 0,07424225 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02823211 0,07416242 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02823211 0,07408277 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02823211 0,07400328 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02823211 0,07392396 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02823211 0,07384481 ! reflex GO:0060004 17 8 0,000 0,02823211 0,07376583 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02823211 0,07368702 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02823211 0,07360838 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02823211 0,07352991 ! pigment granule organization GO:0048753 17 8 0,000 0,02823211 0,0734516 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02823211 0,07337346 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02823211 0,07329549 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02823211 0,07321768 ! histidine catabolic process GO:0006548 10 8 0,000 0,02823211 0,07314004 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02823211 0,07306256 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02823211 0,07298524 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02823211 0,07290809 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,02823211 0,0728311 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02823211 0,07275428 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02823211 0,07267761 ! melanin metabolic process GO:0006582 17 8 0,000 0,02823211 0,07260111 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02823211 0,07252477 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02823211 0,07244859 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02823211 0,07237256 ! macrophage activation GO:0042116 13 8 0,000 0,02823211 0,0722967 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02823211 0,072221 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02823211 0,07214545 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02823211 0,07207007 ! purine salvage GO:0043101 12 8 0,000 0,02823211 0,07199484 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02823211 0,07191976 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02823211 0,07184485 ! osteoblast development GO:0002076 17 8 0,000 0,02823211 0,07177009 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02823211 0,07169548 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02823211 0,07162103 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02823211 0,07154674 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02823211 0,0714726 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02823211 0,07139861 ! response to UV-B GO:0010224 17 8 0,000 0,02823211 0,07132477 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02823211 0,07125109 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02823211 0,07117756 ! intermediate filament organization GO:0045109 12 8 0,000 0,02823211 0,07110418 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02823211 0,07103095 ! cellular extravasation GO:0045123 13 8 0,000 0,02823211 0,07095787 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02823211 0,07088495 ! response to antibiotic GO:0046677 11 8 0,000 0,02823211 0,07081217 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02823211 0,07073954 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02823211 0,07066706 ! DNA topological change GO:0006265 12 8 0,000 0,02823211 0,07059473 ! response to tropane GO:0014073 15 8 0,000 0,02823211 0,07052255 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02823211 0,07045052 ! melanosome transport GO:0032402 13 8 0,000 0,02823211 0,07037863 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02823211 0,07030689 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02823211 0,07023529 ! mast cell activation GO:0045576 14 8 0,000 0,02823211 0,07016384 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02823211 0,07009253 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02823211 0,07002137 ! gas homeostasis GO:0033483 14 8 0,000 0,02823211 0,06995036 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02823211 0,06987949 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02823211 0,06980876 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02823211 0,06973817 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02823211 0,06966773 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02823211 0,06959743 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02823211 0,06952727 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02823211 0,06945726 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02823211 0,06938738 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02823211 0,06931764 ! response to tumor cell GO:0002347 16 8 0,000 0,02823211 0,06924805 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02823211 0,06917859 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02823211 0,06910927 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02823211 0,06904009 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02823211 0,06897105 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02823211 0,06890215 ! hormone catabolic process GO:0042447 17 8 0,000 0,02823211 0,06883339 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02823211 0,06876476 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02823211 0,06869627 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02823211 0,06862791 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02823211 0,0685597 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02823211 0,06849161 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02823211 0,06842367 ! adult feeding behavior GO:0008343 10 8 0,000 0,02823211 0,06835585 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02823211 0,06828817 ! ATP catabolic process GO:0006200 11 8 0,000 0,02823211 0,06822063 ! blastocyst growth GO:0001832 19 8 0,000 0,02823211 0,06815322 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02823211 0,06808594 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02823211 0,06801879 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02823211 0,06795178 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02823211 0,0678849 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02823211 0,06781815 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02823211 0,06775153 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02823211 0,06768504 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02823211 0,06761868 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02823211 0,06755245 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02823211 0,06748635 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02823211 0,06742039 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02823211 0,06735455 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02823211 0,06728883 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02823211 0,06722325 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02823211 0,06715779 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02823211 0,06709247 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02823211 0,06702726 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02823211 0,06696219 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02823211 0,06689724 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,02966457 0,0702234 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,02966457 0,07015542 ! axon guidance GO:0007411 162 75 1,000 0,02966457 0,07008757 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 1,000 0,03039634 0,0717471 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,03113524 0,07342027 ! cytosolic calcium ion homeostasis GO:0051480 149 77 1,000 0,03113524 0,07334947 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,03113524 0,07327881 ! regulation of catabolic process GO:0009894 173 77 1,000 0,03113524 0,07320828 ! axon extension GO:0048675 16 9 0,000 0,03170506 0,0744764 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03170506 0,07440486 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03170506 0,07433345 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03170506 0,07426218 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03170506 0,07419105 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03170506 0,07412005 ! reproductive behavior GO:0019098 22 9 0,000 0,03170506 0,07404919 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03170506 0,07397847 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03170506 0,07390788 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03170506 0,07383742 ! UTP metabolic process GO:0046051 10 9 0,000 0,03170506 0,0737671 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03170506 0,07369691 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03170506 0,07362686 ! artery development GO:0060840 25 9 0,000 0,03170506 0,07355694 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03170506 0,07348715 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03170506 0,07341749 ! equilibrioception GO:0050957 20 9 0,000 0,03170506 0,07334797 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03170506 0,07327858 ! chemosensory behavior GO:0007635 21 9 0,000 0,03170506 0,07320932 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03170506 0,07314018 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03170506 0,07307118 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03170506 0,07300231 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03170506 0,07293357 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03170506 0,07286496 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03170506 0,07279648 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03170506 0,07272813 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03170506 0,0726599 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03170506 0,0725918 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03170506 0,07252383 ! protein targeting to ER GO:0045047 25 9 0,000 0,03170506 0,07245599 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03170506 0,07238828 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,03170506 0,07232069 ! T cell selection GO:0045058 27 9 0,000 0,03170506 0,07225322 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03170506 0,07218589 ! glycine catabolic process GO:0006546 15 9 0,000 0,03170506 0,07211867 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03170506 0,07205159 ! endosome organization GO:0007032 20 9 0,000 0,03170506 0,07198462 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03170506 0,07191779 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03170506 0,07185107 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03170506 0,07178448 ! mannose metabolic process GO:0006013 13 9 0,000 0,03170506 0,07171801 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03170506 0,07165167 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03170506 0,07158545 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03170506 0,07151935 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03170506 0,07145337 ! receptor clustering GO:0043113 20 9 0,000 0,03170506 0,07138752 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03170506 0,07132178 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03170506 0,07125617 ! retinol metabolic process GO:0042572 20 9 0,000 0,03170506 0,07119068 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03170506 0,0711253 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03170506 0,07106005 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03170506 0,07099492 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03170506 0,0709299 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,03170506 0,07086501 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03170506 0,07080023 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03170506 0,07073558 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03170506 0,07067104 ! response to amine stimulus GO:0014075 13 9 0,000 0,03170506 0,07060661 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03170506 0,07054231 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03170506 0,07047812 ! erythrocyte development GO:0048821 17 9 0,000 0,03170506 0,07041405 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03170506 0,0703501 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03170506 0,07028626 ! postreplication repair GO:0006301 25 9 0,000 0,03170506 0,07022253 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03170506 0,07015893 ! icosanoid secretion GO:0032309 15 9 0,000 0,03170506 0,07009543 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03170506 0,07003206 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03170506 0,06996879 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03170506 0,06990565 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03170506 0,06984261 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03170506 0,06977969 ! sterol catabolic process GO:0016127 14 9 0,000 0,03170506 0,06971688 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03170506 0,06965419 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03170506 0,0695916 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03170506 0,06952913 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03170506 0,06946678 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03170506 0,06940453 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03170506 0,0693424 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,03170506 0,06928037 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03170506 0,06921846 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03170506 0,06915666 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03170506 0,06909496 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03170506 0,06903338 ! purine base metabolic process GO:0006144 25 9 0,000 0,03170506 0,06897191 ! pigment granule transport GO:0051904 17 9 0,000 0,03170506 0,06891055 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,03170506 0,06884929 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03170506 0,06878815 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03170506 0,06872711 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03170506 0,06866618 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03170506 0,06860536 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03170506 0,06854465 ! mitochondrion localization GO:0051646 18 9 0,000 0,03170506 0,06848405 ! antigen processing and presentation GO:0019882 117 78 1,000 0,03188124 0,06880376 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,03416113 0,07365899 ! protein import into nucleus GO:0006606 174 82 1,000 0,03493487 0,07526092 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03516569 0,07569143 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,03516569 0,0756248 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03516569 0,07555829 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03516569 0,07549189 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03516569 0,07542561 ! associative learning GO:0008306 21 10 0,000 0,03516569 0,07535945 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,03516569 0,0752934 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03516569 0,07522747 ! phosphate transport GO:0006817 24 10 0,000 0,03516569 0,07516166 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03516569 0,07509595 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03516569 0,07503037 ! CTP metabolic process GO:0046036 11 10 0,000 0,03516569 0,0749649 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,03516569 0,07489954 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03516569 0,0748343 ! GTP metabolic process GO:0046039 11 10 0,000 0,03516569 0,07476917 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03516569 0,07470415 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03516569 0,07463925 ! social behavior GO:0035176 29 10 0,000 0,03516569 0,07457446 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03516569 0,07450978 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03516569 0,07444521 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03516569 0,07438076 ! androgen metabolic process GO:0008209 17 10 0,000 0,03516569 0,07431641 ! phospholipid efflux GO:0033700 19 10 0,000 0,03516569 0,07425218 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03516569 0,07418806 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03516569 0,07412405 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03516569 0,07406015 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03516569 0,07399636 ! pathogenesis GO:0009405 17 10 0,000 0,03516569 0,07393268 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03516569 0,07386911 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03516569 0,07380565 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03516569 0,07374229 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,03516569 0,07367905 ! endoderm development GO:0007492 18 10 0,000 0,03516569 0,07361591 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03516569 0,07355289 ! arginine catabolic process GO:0006527 17 10 0,000 0,03516569 0,07348997 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03516569 0,07342716 ! proline metabolic process GO:0006560 13 10 0,000 0,03516569 0,07336445 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03516569 0,07330185 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03516569 0,07323936 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03516569 0,07317698 ! V(D)J recombination GO:0033151 34 10 0,000 0,03516569 0,0731147 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03516569 0,07305253 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03516569 0,07299046 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03516569 0,0729285 ! B cell proliferation GO:0042100 19 10 0,000 0,03516569 0,07286664 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03516569 0,07280489 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03516569 0,07274325 ! multicellular organism growth GO:0035264 19 10 0,000 0,03516569 0,0726817 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03516569 0,07262026 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03516569 0,07255893 ! ruffle organization GO:0031529 17 10 0,000 0,03516569 0,0724977 ! epithelial cell development GO:0002064 21 10 0,000 0,03516569 0,07243657 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03516569 0,07237555 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03516569 0,07231462 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03516569 0,0722538 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03516569 0,07219309 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03516569 0,07213247 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03516569 0,07207196 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,03516569 0,07201154 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03516569 0,07195123 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03516569 0,07189102 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03516569 0,07183091 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03516569 0,0717709 ! segment specification GO:0007379 15 10 0,000 0,03516569 0,071711 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03516569 0,07165119 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03516569 0,07159148 ! response to dsRNA GO:0043331 23 10 0,000 0,03516569 0,07153187 ! DNA ligation GO:0006266 18 10 0,000 0,03516569 0,07147236 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03516569 0,07141294 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03516569 0,07135363 ! melanosome localization GO:0032400 16 10 0,000 0,03516569 0,07129442 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03516569 0,0712353 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03516569 0,07117628 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03516569 0,07111736 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03516569 0,07105854 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03516569 0,07099981 ! induction of an organ GO:0001759 17 10 0,000 0,03516569 0,07094118 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03516569 0,07088265 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03516569 0,07082421 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03516569 0,07076588 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03516569 0,07070763 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03516569 0,07064948 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03516569 0,07059143 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03516569 0,07053347 ! salivary gland development GO:0007431 28 10 0,000 0,03516569 0,07047561 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03516569 0,07041785 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03516569 0,07036017 ! midbrain development GO:0030901 14 10 0,000 0,03516569 0,0703026 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03516569 0,07024511 GO:0050879|multicellular organismal movement, ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03516569 0,07018772 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,03516569 0,07013043 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03516569 0,07007322 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03516569 0,07001611 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03516569 0,0699591 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03516569 0,06990217 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03516569 0,06984534 ! detection of calcium ion GO:0005513 24 10 0,000 0,03516569 0,0697886 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03516569 0,06973196 ! blastocyst formation GO:0001825 18 10 0,000 0,03516569 0,0696754 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03516569 0,06961894 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03516569 0,06956257 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03516569 0,06950629 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03516569 0,0694501 ! response to nicotine GO:0035094 20 10 0,000 0,03516569 0,069394 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03516569 0,06933799 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,0357154 0,0703651 ! response to drug GO:0042493 149 83 1,000 0,0357154 0,0703084 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,0357154 0,07025179 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,0357154 0,07019527 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,0357154 0,07013884 ! nuclear import GO:0051170 177 83 1,000 0,0357154 0,07008251 ! response to metal ion GO:0010038 158 84 1,000 0,03650267 0,07156983 ! T cell activation GO:0042110 189 84 1,000 0,03650267 0,07151244 ! negative regulation of growth GO:0045926 168 85 1,000 0,03729661 0,0730093 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,03729661 0,07295085 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,03729661 0,07289249 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,03809717 0,07439759 ! regulation of lyase activity GO:0051339 169 86 1,000 0,03809717 0,07433817 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,03861404 0,0752866 ! respiratory burst GO:0045730 17 11 0,000 0,03861404 0,07522656 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,03861404 0,07516662 ! neuron fate specification GO:0048665 18 11 0,000 0,03861404 0,07510678 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03861404 0,07504703 ! thyroid gland development GO:0030878 26 11 0,000 0,03861404 0,07498737 ! synapsis GO:0007129 14 11 0,000 0,03861404 0,07492781 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03861404 0,07486834 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,03861404 0,07480897 ! response to pain GO:0048265 27 11 0,000 0,03861404 0,07474969 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03861404 0,07469051 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,03861404 0,07463142 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,03861404 0,07457242 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,03861404 0,07451352 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03861404 0,07445471 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03861404 0,07439599 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03861404 0,07433736 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03861404 0,07427883 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03861404 0,07422039 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03861404 0,07416204 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,03861404 0,07410378 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,03861404 0,07404561 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,03861404 0,07398754 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03861404 0,07392955 ! UV protection GO:0009650 20 11 0,000 0,03861404 0,07387166 ! adult heart development GO:0007512 16 11 0,000 0,03861404 0,07381386 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,03861404 0,07375615 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03861404 0,07369852 ! macroautophagy GO:0016236 19 11 0,000 0,03861404 0,07364099 ! temperature homeostasis GO:0001659 18 11 0,000 0,03861404 0,07358355 ! behavioral fear response GO:0001662 27 11 0,000 0,03861404 0,0735262 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03861404 0,07346893 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03861404 0,07341176 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,03861404 0,07335467 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,03861404 0,07329768 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03861404 0,07324077 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,03861404 0,07318395 ! regulation of organ growth GO:0046620 14 11 0,000 0,03861404 0,07312722 ! pigment granule localization GO:0051875 20 11 0,000 0,03861404 0,07307057 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03861404 0,07301402 ! vasoconstriction GO:0042310 20 11 0,000 0,03861404 0,07295755 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,03861404 0,07290117 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03861404 0,07284487 ! embryonic axis specification GO:0000578 19 11 0,000 0,03861404 0,07278867 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03861404 0,07273255 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03861404 0,07267651 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03861404 0,07262056 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03861404 0,0725647 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03861404 0,07250892 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03861404 0,07245323 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,03861404 0,07239763 ! prophase GO:0051324 17 11 0,000 0,03861404 0,07234211 ! neuroblast proliferation GO:0007405 25 11 0,000 0,03861404 0,07228668 ! nucleosome positioning GO:0016584 15 11 0,000 0,03861404 0,07223133 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03861404 0,07217606 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03861404 0,07212088 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03861404 0,07206578 ! acid secretion GO:0046717 20 11 0,000 0,03861404 0,07201077 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03861404 0,07195584 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03861404 0,071901 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03861404 0,07184624 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03861404 0,07179156 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,03861404 0,07173697 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,03861404 0,07168246 ! cholesterol efflux GO:0033344 21 11 0,000 0,03861404 0,07162803 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03861404 0,07157368 ! oocyte development GO:0048599 20 11 0,000 0,03861404 0,07151942 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,03861404 0,07146524 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 19 11 0,000 0,03861404 0,07141114 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03861404 0,07135712 ! activation of innate immune response GO:0002218 16 11 0,000 0,03861404 0,07130318 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03861404 0,07124933 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,03861404 0,07119556 ! lysogeny GO:0030069 22 11 0,000 0,03861404 0,07114186 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03861404 0,07108825 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,03861404 0,07103472 ! regulation of protein transport GO:0051223 165 87 1,000 0,03890429 0,07151481 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 167 88 1,000 0,03971792 0,07295555 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,04053801 0,07440597 ! regulation of DNA binding GO:0051101 167 89 1,000 0,04053801 0,07435011 ! protein localization in nucleus GO:0034504 192 89 1,000 0,04053801 0,07429433 ! response to inorganic substance GO:0010035 173 90 1,000 0,04136448 0,0757522 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,04205018 0,07695025 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,04205018 0,07689265 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,04205018 0,07683514 ! mating GO:0007618 17 12 0,000 0,04205018 0,07677771 ! protein complex disassembly GO:0043241 28 12 0,000 0,04205018 0,07672037 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04205018 0,07666312 ! hippocampus development GO:0021766 29 12 0,000 0,04205018 0,07660595 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,04205018 0,07654887 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04205018 0,07649187 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,04205018 0,07643495 ! ventral spinal cord development GO:0021517 25 12 0,000 0,04205018 0,07637812 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,04205018 0,07632138 ! drug transport GO:0015893 16 12 0,000 0,04205018 0,07626472 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,04205018 0,07620814 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,04205018 0,07615165 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,04205018 0,07609524 ! polyamine metabolic process GO:0006595 18 12 0,000 0,04205018 0,07603892 ! focal adhesion formation GO:0048041 37 12 0,000 0,04205018 0,07598268 ! mitotic spindle organization GO:0007052 23 12 0,000 0,04205018 0,07592652 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,04205018 0,07587044 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,04205018 0,07581445 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,04205018 0,07575854 ! lipid digestion GO:0044241 21 12 0,000 0,04205018 0,07570271 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,04205018 0,07564696 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04205018 0,0755913 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,04205018 0,07553572 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,04205018 0,07548022 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04205018 0,0754248 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,04205018 0,07536946 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,04205018 0,07531421 ! snRNA metabolic process GO:0016073 30 12 0,000 0,04205018 0,07525903 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,04205018 0,07520394 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,04205018 0,07514892 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04205018 0,07509399 ! cranial nerve development GO:0021545 23 12 0,000 0,04205018 0,07503914 ! fucose catabolic process GO:0019317 25 12 0,000 0,04205018 0,07498436 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,04205018 0,07492967 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,04205018 0,07487506 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04205018 0,07482052 ! zymogen activation GO:0031638 18 12 0,000 0,04205018 0,07476607 ! T cell homeostasis GO:0043029 28 12 0,000 0,04205018 0,07471169 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,04205018 0,0746574 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,04205018 0,07460318 ! oocyte differentiation GO:0009994 21 12 0,000 0,04205018 0,07454904 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,04205018 0,07449498 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,04205018 0,074441 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,04205018 0,07438709 GO:0042130|negative regulation of T cell proliferation, ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,04205018 0,07433327 ! defense response to fungus GO:0050832 15 12 0,000 0,04205018 0,07427952 ! developmental induction GO:0031128 22 12 0,000 0,04205018 0,07422585 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,04205018 0,07417226 ! lamellipodium assembly GO:0030032 24 12 0,000 0,04205018 0,07411874 ! response to cold GO:0009409 17 12 0,000 0,04205018 0,0740653 ! establishment of cell polarity GO:0030010 21 12 0,000 0,04205018 0,07401194 ! regulation of synapse organization GO:0050807 18 12 0,000 0,04205018 0,07395866 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,0421973 0,07416403 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 1,000 0,0421973 0,07411071 ! bone development GO:0060348 206 92 1,000 0,0430364 0,07553012 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,04547412 0,0797511 ! 'de novo' protein folding GO:0006458 26 13 0,000 0,04547412 0,07969389 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04547412 0,07963676 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04547412 0,07957971 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,04547412 0,07952275 ! peroxisomal transport GO:0043574 28 13 0,000 0,04547412 0,07946586 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,04547412 0,07940906 ! cartilage condensation GO:0001502 22 13 0,000 0,04547412 0,07935234 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,04547412 0,0792957 ! organelle fusion GO:0048284 36 13 0,000 0,04547412 0,07923914 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,04547412 0,07918266 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,04547412 0,07912627 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,04547412 0,07906995 ! endocrine pancreas development GO:0031018 25 13 0,000 0,04547412 0,07901371 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,04547412 0,07895755 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,04547412 0,07890147 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,04547412 0,07884548 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,04547412 0,07878956 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,04547412 0,07873372 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04547412 0,07867796 ! methionine metabolic process GO:0006555 31 13 0,000 0,04547412 0,07862228 ! plasma membrane organization GO:0007009 27 13 0,000 0,04547412 0,07856667 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,04547412 0,07851115 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,04547412 0,0784557 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,04547412 0,07840034 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,04547412 0,07834505 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,04547412 0,07828984 ! cytokine metabolic process GO:0042107 24 13 0,000 0,04547412 0,0782347 ! exocrine system development GO:0035272 34 13 0,000 0,04547412 0,07817965 ! monoamine transport GO:0015844 21 13 0,000 0,04547412 0,07812467 ! L-glutamate transport GO:0015813 30 13 0,000 0,04547412 0,07806977 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,04547412 0,07801494 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,04547412 0,07796019 ! protein homotetramerization GO:0051289 24 13 0,000 0,04547412 0,07790552 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,04547412 0,07785093 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,04547412 0,07779641 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,04547412 0,07774197 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,04547412 0,07768761 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,04547412 0,07763332 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04547412 0,0775791 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,04547412 0,07752497 ! histone methylation GO:0016571 29 13 0,000 0,04547412 0,0774709 ! chromatin silencing GO:0006342 29 13 0,000 0,04547412 0,07741692 ! gland morphogenesis GO:0022612 31 13 0,000 0,04547412 0,07736301 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,04547412 0,07730917 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,04547412 0,07725541 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04547412 0,07720172 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,04547412 0,07714811 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,04547412 0,07709457 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,04547412 0,07704111 ! spleen development GO:0048536 24 13 0,000 0,04547412 0,07698772 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,04547412 0,0769344 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,04547412 0,07688116 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,04547412 0,07682799 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,04547412 0,0767749 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04547412 0,07672188 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,04547412 0,07666893 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,04547412 0,07661605 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,04547412 0,07656325 ! insulin secretion GO:0030073 24 13 0,000 0,04547412 0,07651052 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,04547412 0,07645786 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,04547412 0,07640528 ! acrosome reaction GO:0007340 19 13 0,000 0,04547412 0,07635277 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,04547412 0,07630033 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,04547412 0,07624796 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,04559086 0,07639127 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,04559086 0,07633891 ! regulation of protein localization GO:0032880 188 97 1,000 0,04732426 0,07918711 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,04819993 0,08059715 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,04819993 0,08054202 ! rRNA transcription GO:0009303 28 14 0,000 0,04888592 0,08163248 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,04888592 0,08157672 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,04888592 0,08152103 ! water transport GO:0006833 21 14 0,000 0,04888592 0,08146542 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,04888592 0,08140989 ! non-recombinational repair GO:0000726 29 14 0,000 0,04888592 0,08135444 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,04888592 0,08129906 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,04888592 0,08124375 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,04888592 0,08118852 ! RNA polyadenylation GO:0043631 32 14 0,000 0,04888592 0,08113336 ! lipid localization GO:0010876 32 14 0,000 0,04888592 0,08107828 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,04888592 0,08102328 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,04888592 0,08096835 ! regulated secretory pathway GO:0045055 24 14 0,000 0,04888592 0,08091349 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,04888592 0,08085871 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,04888592 0,080804 ! arginine metabolic process GO:0006525 21 14 0,000 0,04888592 0,08074937 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,04888592 0,08069481 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,04888592 0,08064032 ! regulation of heart rate GO:0002027 25 14 0,000 0,04888592 0,08058591 ! fear response GO:0042596 34 14 0,000 0,04888592 0,08053157 ! organic alcohol transport GO:0015850 29 14 0,000 0,04888592 0,0804773 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,04888592 0,08042311 ! embryo implantation GO:0007566 30 14 0,000 0,04888592 0,08036899 ! neutral amino acid transport GO:0015804 28 14 0,000 0,04888592 0,08031494 ! bone mineralization GO:0030282 18 14 0,000 0,04888592 0,08026096 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,04888592 0,08020706 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,04888592 0,08015323 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,04888592 0,08009947 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,04888592 0,08004579 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,04888592 0,07999217 ! regulation of cellular pH GO:0030641 27 14 0,000 0,04888592 0,07993863 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,04888592 0,07988516 ! ribosome assembly GO:0042255 18 14 0,000 0,04888592 0,07983176 ! cerebellum development GO:0021549 23 14 0,000 0,04888592 0,07977843 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,04888592 0,07972517 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,04888592 0,07967199 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,04888592 0,07961887 ! response to gamma radiation GO:0010332 30 14 0,000 0,04888592 0,07956583 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,04888592 0,07951286 ! NADP metabolic process GO:0006739 24 14 0,000 0,04888592 0,07945995 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,04888592 0,07940712 ! oxygen transport GO:0015671 22 14 0,000 0,04888592 0,07935436 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04888592 0,07930167 ! male genitalia development GO:0030539 26 14 0,000 0,04888592 0,07924905 ! regulation of axon extension GO:0030516 43 14 0,000 0,04888592 0,07919649 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,04888592 0,07914401 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,04888592 0,0790916 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,04888592 0,07903925 ! mRNA transport GO:0051028 185 100 1,000 0,04996894 0,08073685 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05228563 0,08442418 ! lactation GO:0007595 30 15 0,000 0,05228563 0,08436842 ! reproductive cellular process GO:0048610 22 15 0,000 0,05228563 0,08431273 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05228563 0,08425712 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,05228563 0,08420157 ! superoxide anion generation GO:0042554 22 15 0,000 0,05228563 0,08414611 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,05228563 0,08409071 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,05228563 0,08403539 ! copper ion transport GO:0006825 22 15 0,000 0,05228563 0,08398014 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,05228563 0,08392496 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,05228563 0,08386985 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,05228563 0,08381482 ! sulfate transport GO:0008272 27 15 0,000 0,05228563 0,08375986 ! response to cAMP GO:0051591 25 15 0,000 0,05228563 0,08370497 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,05228563 0,08365016 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,05228563 0,08359541 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,05228563 0,08354074 ! response to hexose stimulus GO:0009746 25 15 0,000 0,05228563 0,08348614 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,05228563 0,08343161 ! vesicle coating GO:0006901 38 15 0,000 0,05228563 0,08337715 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,05228563 0,08332276 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,05228563 0,08326844 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,05228563 0,08321419 ! regulation of exocytosis GO:0017157 26 15 0,000 0,05228563 0,08316002 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,05228563 0,08310591 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,05228563 0,08305188 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,05228563 0,08299791 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,05228563 0,08294402 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,05228563 0,08289019 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,05228563 0,08283644 ! histone deacetylation GO:0016575 24 15 0,000 0,05228563 0,08278275 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05228563 0,08272914 ! cofactor transport GO:0051181 30 15 0,000 0,05228563 0,08267559 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05228563 0,08262211 ! muscle maintenance GO:0046716 26 15 0,000 0,05228563 0,08256871 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,05228563 0,08251537 ! intestinal absorption GO:0050892 31 15 0,000 0,05228563 0,0824621 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05228563 0,0824089 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,05228563 0,08235576 ! heme biosynthetic process GO:0006783 33 15 0,000 0,05228563 0,0823027 ! cell killing GO:0001906 32 15 0,000 0,05228563 0,0822497 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,05228563 0,08219678 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,05228563 0,08214392 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,05228563 0,08209112 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,05228563 0,0820384 ! actin filament polymerization GO:0030041 27 15 0,000 0,05228563 0,08198574 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,05228563 0,08193316 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,05567328 0,08718578 ! positive regulation of cell size GO:0045793 29 16 0,000 0,05567328 0,08712992 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,05567328 0,08707414 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,05567328 0,08701843 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,05567328 0,0869628 ! bone remodeling GO:0046849 28 16 0,000 0,05567328 0,08690723 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,05567328 0,08685173 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,05567328 0,08679631 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05567328 0,08674095 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,05567328 0,08668567 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,05567328 0,08663045 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,05567328 0,08657531 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,05567328 0,08652024 ! startle response GO:0001964 28 16 0,000 0,05567328 0,08646523 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,05567328 0,0864103 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,05567328 0,08635544 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,05567328 0,08630064 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,05567328 0,08624592 ! protein polyubiquitination GO:0000209 41 16 0,000 0,05567328 0,08619126 ! glutamate metabolic process GO:0006536 25 16 0,000 0,05567328 0,08613668 ! pituitary gland development GO:0021983 30 16 0,000 0,05567328 0,08608216 ! response to osmotic stress GO:0006970 27 16 0,000 0,05567328 0,08602771 ! lysosomal transport GO:0007041 31 16 0,000 0,05567328 0,08597333 ! fructose metabolic process GO:0006000 25 16 0,000 0,05567328 0,08591902 ! L-amino acid transport GO:0015807 33 16 0,000 0,05567328 0,08586478 ! stem cell development GO:0048864 46 16 0,000 0,05567328 0,08581061 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05567328 0,0857565 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05567328 0,08570246 ! intermediate filament-based process GO:0045103 36 16 0,000 0,05567328 0,0856485 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,05567328 0,0855946 ! negative regulation of immune response GO:0050777 38 16 0,000 0,05567328 0,08554076 ! axon cargo transport GO:0008088 46 16 0,000 0,05567328 0,085487 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,05567328 0,0854333 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,05567328 0,08537967 ! neuron recognition GO:0008038 40 16 0,000 0,05567328 0,08532611 ! mRNA splice site selection GO:0006376 44 16 0,000 0,05567328 0,08527261 ! tissue regeneration GO:0042246 27 16 0,000 0,05567328 0,08521918 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,05567328 0,08516582 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,05567328 0,08511252 ! biomineral formation GO:0031214 22 16 0,000 0,05567328 0,08505929 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,05567328 0,08500613 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,05567328 0,08495304 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,05567328 0,08490001 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05567328 0,08484704 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,05567328 0,08479415 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,05567328 0,08474132 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,05567328 0,08468855 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,05567328 0,08463585 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,05567328 0,08458322 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,05904891 0,08965599 ! metencephalon development GO:0022037 32 17 0,000 0,05904891 0,0896003 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,05904891 0,08954468 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,05904891 0,08948913 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,05904891 0,08943365 ! signal complex assembly GO:0007172 47 17 0,000 0,05904891 0,08937824 ! endothelial cell migration GO:0043542 31 17 0,000 0,05904891 0,0893229 ! gene silencing by RNA GO:0031047 38 17 0,000 0,05904891 0,08926763 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,05904891 0,08921242 ! glial cell development GO:0021782 28 17 0,000 0,05904891 0,08915728 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,05904891 0,08910221 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,05904891 0,08904721 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,05904891 0,08899228 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,05904891 0,08893741 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,05904891 0,08888261 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,05904891 0,08882788 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,05904891 0,08877322 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,05904891 0,08871862 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,05904891 0,0886641 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,05904891 0,08860963 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,05904891 0,08855524 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,05904891 0,08850091 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,05904891 0,08844665 ! membrane budding GO:0006900 42 17 0,000 0,05904891 0,08839245 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,05904891 0,08833832 ! regulation of protein binding GO:0043393 33 17 0,000 0,05904891 0,08828426 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,05904891 0,08823027 ! genitalia development GO:0048806 32 17 0,000 0,05904891 0,08817633 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,05904891 0,08812247 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,05904891 0,08806867 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,05904891 0,08801494 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,05904891 0,08796127 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,05904891 0,08790767 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,05904891 0,08785413 ! steroid catabolic process GO:0006706 34 17 0,000 0,05904891 0,08780066 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,05904891 0,08774725 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,05904891 0,08769391 ! gas transport GO:0015669 26 17 0,000 0,05904891 0,08764063 ! organic cation transport GO:0015695 32 17 0,000 0,05904891 0,08758742 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,05904891 0,08753427 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,05904891 0,08748119 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,06241257 0,09240843 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,06241257 0,09235246 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,06241257 0,09229655 ! limbic system development GO:0021761 40 18 0,000 0,06241257 0,09224072 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06241257 0,09218495 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,06241257 0,09212925 ! adult walking behavior GO:0007628 36 18 0,000 0,06241257 0,09207362 ! heart looping GO:0001947 34 18 0,000 0,06241257 0,09201805 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,06241257 0,09196255 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,06241257 0,09190712 ! centrosome cycle GO:0007098 26 18 0,000 0,06241257 0,09185175 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,06241257 0,09179645 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,06241257 0,09174122 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,06241257 0,09168605 ! glycine metabolic process GO:0006544 30 18 0,000 0,06241257 0,09163095 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06241257 0,09157592 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,06241257 0,09152095 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,06241257 0,09146605 ! DNA integration GO:0015074 32 18 0,000 0,06241257 0,09141122 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,06241257 0,09135645 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,06241257 0,09130174 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,06241257 0,0912471 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,06241257 0,09119253 ! neural crest cell migration GO:0001755 41 18 0,000 0,06241257 0,09113802 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,06241257 0,09108358 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,06241257 0,0910292 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,06241257 0,09097489 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,06241257 0,09092064 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,06241257 0,09086645 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,06241257 0,09081233 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,06241257 0,09075828 ! detection of bacterium GO:0016045 22 18 0,000 0,06241257 0,09070429 ! nerve development GO:0021675 34 18 0,000 0,06241257 0,09065036 ! defense response to virus GO:0051607 43 18 0,000 0,06241257 0,0905965 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,06241257 0,0905427 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,06241257 0,09048897 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,0657643 0,09529193 ! positive regulation of translation GO:0045727 31 19 0,000 0,0657643 0,09523544 ! negative regulation of defense response GO:0031348 27 19 0,000 0,0657643 0,09517902 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,0657643 0,09512267 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,0657643 0,09506638 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,0657643 0,09501016 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,0657643 0,09495401 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,0657643 0,09489792 ! inositol metabolic process GO:0006020 33 19 0,000 0,0657643 0,0948419 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0657643 0,09478595 ! memory GO:0007613 34 19 0,000 0,0657643 0,09473006 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,0657643 0,09467424 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,0657643 0,09461848 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,0657643 0,09456279 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,0657643 0,09450717 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,0657643 0,09445161 ! cerebral cortex development GO:0021987 40 19 0,000 0,0657643 0,09439611 ! pigmentation during development GO:0048066 42 19 0,000 0,0657643 0,09434069 ! heme metabolic process GO:0042168 40 19 0,000 0,0657643 0,09428532 ! neuromuscular junction development GO:0007528 43 19 0,000 0,0657643 0,09423002 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,0657643 0,09417479 ! response to fungus GO:0009620 26 19 0,000 0,0657643 0,09411962 ! peptide cross-linking GO:0018149 39 19 0,000 0,0657643 0,09406451 ! heart process GO:0003015 32 19 0,000 0,0657643 0,09400947 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,0657643 0,0939545 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,0657643 0,09389958 ! visual learning GO:0008542 38 19 0,000 0,0657643 0,09384474 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,0657643 0,09378995 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,0657643 0,09373523 ! vitamin transport GO:0051180 31 19 0,000 0,0657643 0,09368058 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,0657643 0,09362598 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,0657643 0,09357145 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,0657643 0,09351699 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,0657643 0,09346259 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,0657643 0,09340825 ! cilium assembly GO:0042384 38 19 0,000 0,0657643 0,09335397 ! peptide hormone secretion GO:0030072 32 19 0,000 0,0657643 0,09329976 ! protein secretion GO:0009306 45 20 0,000 0,06910414 0,09798109 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,06910414 0,09792426 ! positive regulation of ossification GO:0045778 50 20 0,000 0,06910414 0,09786749 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,06910414 0,09781079 ! skin development GO:0043588 42 20 0,000 0,06910414 0,09775415 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,06910414 0,09769758 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,06910414 0,09764108 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,06910414 0,09758464 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,06910414 0,09752826 ! bile acid metabolic process GO:0008206 34 20 0,000 0,06910414 0,09747195 ! response to alkaloid GO:0043279 38 20 0,000 0,06910414 0,09741571 ! retinoid metabolic process GO:0001523 34 20 0,000 0,06910414 0,09735953 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,06910414 0,09730341 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,06910414 0,09724736 ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,06910414 0,09719138 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,06910414 0,09713546 ! actin filament bundle formation GO:0051017 47 20 0,000 0,06910414 0,0970796 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,06910414 0,09702381 ! peptide secretion GO:0002790 38 20 0,000 0,06910414 0,09696808 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,06910414 0,09691241 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,06910414 0,09685681 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,06910414 0,09680128 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,06910414 0,0967458 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,06910414 0,09669039 ! cell-cell junction organization GO:0045216 43 20 0,000 0,06910414 0,09663505 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,06910414 0,09657976 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,06910414 0,09652454 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,06910414 0,09646939 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,06910414 0,09641429 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,06910414 0,09635926 ! regulation of glucose import GO:0046324 30 20 0,000 0,06910414 0,09630429 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,06910414 0,09624939 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,06910414 0,09619454 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,06910414 0,09613976 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,06910414 0,09608505 ! regulation of cell killing GO:0031341 46 21 0,000 0,07243214 0,10065513 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,07243214 0,10059791 ! hormone secretion GO:0046879 39 21 0,000 0,07243214 0,10054075 ! cAMP metabolic process GO:0046058 41 21 0,000 0,07243214 0,10048366 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,07243214 0,10042663 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,07243214 0,10036967 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,07243214 0,10031277 ! ovarian follicle development GO:0001541 39 21 0,000 0,07243214 0,10025593 ! smooth muscle contraction GO:0006939 48 21 0,000 0,07243214 0,10019916 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,07243214 0,10014246 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,07243214 0,10008582 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,07243214 0,10002924 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,07243214 0,09997272 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,07243214 0,09991627 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,07243214 0,09985989 ! sensory perception of pain GO:0019233 33 21 0,000 0,07243214 0,09980357 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,07243214 0,09974731 ! diencephalon development GO:0021536 36 21 0,000 0,07243214 0,09969111 ! collagen fibril organization GO:0030199 62 21 0,000 0,07243214 0,09963498 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,07243214 0,09957891 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,07243214 0,0995229 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,07243214 0,09946696 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,07243214 0,09941108 ! collagen catabolic process GO:0030574 29 21 0,000 0,07243214 0,09935526 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,07243214 0,09929951 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,07243214 0,09924381 ! sperm-egg recognition GO:0035036 23 21 0,000 0,07243214 0,09918818 ! actin filament-based movement GO:0030048 47 21 0,000 0,07243214 0,09913262 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,07243214 0,09907711 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,07574833 0,10355522 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,07574833 0,1034973 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,07574833 0,10343945 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,07574833 0,10338167 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,07574833 0,10332394 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,07574833 0,10326628 ! microtubule-based transport GO:0010970 59 22 0,000 0,07574833 0,10320869 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,07574833 0,10315116 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,07574833 0,10309369 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,07574833 0,10303629 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,07574833 0,10297895 ! cellular response to starvation GO:0009267 37 22 0,000 0,07574833 0,10292168 ! vacuolar transport GO:0007034 41 22 0,000 0,07574833 0,10286447 ! central nervous system neuron development GO:0021954 47 22 0,000 0,07574833 0,10280732 ! fucose metabolic process GO:0006004 44 22 0,000 0,07574833 0,10275024 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,07574833 0,10269322 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,07574833 0,10263626 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,07574833 0,10257937 ! stem cell differentiation GO:0048863 57 22 0,000 0,07574833 0,10252254 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,07574833 0,10246577 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,07574833 0,10240907 ! cytolysis GO:0019835 27 22 0,000 0,07574833 0,10235242 ! vasodilation GO:0042311 40 22 0,000 0,07574833 0,10229584 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,07574833 0,10223933 ! G1 phase GO:0051318 44 22 0,000 0,07574833 0,10218287 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,07574833 0,10212648 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,07574833 0,10207015 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,07574833 0,10201388 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,07574833 0,10195768 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,07574833 0,10190153 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,07574833 0,10184545 ! sarcomere organization GO:0045214 32 22 0,000 0,07574833 0,10178943 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,07574833 0,10173347 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,07574833 0,10167757 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,07574833 0,10162174 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,07574833 0,10156596 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,07574833 0,10151025 ! gut development GO:0048565 44 22 0,000 0,07574833 0,10145459 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,07574833 0,101399 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,07574833 0,10134347 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,07574833 0,101288 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,07905276 0,10564874 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,07905276 0,10559098 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,07905276 0,10553328 ! gluconeogenesis GO:0006094 38 23 0,000 0,07905276 0,10547564 ! glycerol metabolic process GO:0006071 40 23 0,000 0,07905276 0,10541807 ! viral genome replication GO:0019079 44 23 0,000 0,07905276 0,10536056 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,07905276 0,10530311 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,07905276 0,10524572 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,07905276 0,1051884 ! regeneration GO:0031099 42 23 0,000 0,07905276 0,10513114 ! axis specification GO:0009798 43 23 0,000 0,07905276 0,10507394 ! visual behavior GO:0007632 46 23 0,000 0,07905276 0,1050168 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,07905276 0,10495973 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,07905276 0,10490272 ! response to ethanol GO:0045471 47 23 0,000 0,07905276 0,10484577 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,07905276 0,10478888 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,07905276 0,10473205 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,07905276 0,10467529 ! peroxisome organization GO:0007031 43 23 0,000 0,07905276 0,10461858 ! lysosome organization GO:0007040 47 23 0,000 0,07905276 0,10456194 ! vesicle targeting GO:0006903 49 23 0,000 0,07905276 0,10450536 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,07905276 0,10444884 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,07905276 0,10439238 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,07905276 0,10433598 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,07905276 0,10427965 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,07905276 0,10422337 ! fatty acid transport GO:0015908 47 23 0,000 0,07905276 0,10416715 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,07905276 0,104111 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,07905276 0,1040549 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,07905276 0,10399887 ! hormone transport GO:0009914 41 23 0,000 0,07905276 0,1039429 ! cell-cell recognition GO:0009988 28 23 0,000 0,07905276 0,10388698 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,07905276 0,10383113 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,07905276 0,10377534 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,07905276 0,1037196 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,08234547 0,10798174 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,08234547 0,10792381 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,08234547 0,10786595 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,08234547 0,10780814 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,08234547 0,1077504 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,08234547 0,10769271 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,08234547 0,10763509 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,08234547 0,10757753 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,08234547 0,10752004 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,08234547 0,1074626 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,08234547 0,10740523 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,08234547 0,10734791 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,08234547 0,10729066 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,08234547 0,10723347 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,08234547 0,10717634 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,08234547 0,10711927 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,08234547 0,10706226 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,08234547 0,10700531 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,08234547 0,10694843 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,08234547 0,1068916 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,08234547 0,10683483 ! membrane depolarization GO:0051899 45 24 0,000 0,08234547 0,10677813 ! pallium development GO:0021543 56 24 0,000 0,08234547 0,10672148 ! oogenesis GO:0048477 44 24 0,000 0,08234547 0,10666489 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,08234547 0,10660837 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,08234547 0,1065519 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,08234547 0,10649549 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,08234547 0,10643915 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,08234547 0,10638286 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,08234547 0,10632663 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,08234547 0,10627046 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,08234547 0,10621436 ! regulation of amine transport GO:0051952 41 24 0,000 0,08234547 0,10615831 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,08234547 0,10610232 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,0856265 0,11027177 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,0856265 0,11021367 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,0856265 0,11015563 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,0856265 0,11009765 ! leukocyte adhesion GO:0007159 55 25 0,000 0,0856265 0,11003974 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0856265 0,10998188 ! phototransduction GO:0007602 37 25 0,000 0,0856265 0,10992409 ! keratinization GO:0031424 37 25 0,000 0,0856265 0,10986636 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,0856265 0,10980868 ! vacuole organization GO:0007033 49 25 0,000 0,0856265 0,10975107 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0856265 0,10969352 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,0856265 0,10963603 ! receptor metabolic process GO:0043112 53 25 0,000 0,0856265 0,1095786 ! chromosome condensation GO:0030261 48 25 0,000 0,0856265 0,10952123 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,0856265 0,10946392 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,0856265 0,10940666 ! immunoglobulin production GO:0002377 62 25 0,000 0,0856265 0,10934947 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0856265 0,10929234 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,0856265 0,10923527 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0856265 0,10917826 ! liver development GO:0001889 55 25 0,000 0,0856265 0,10912131 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,08889589 0,11322871 ! myelination GO:0042552 50 26 0,000 0,08889589 0,1131697 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,08889589 0,11311076 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,08889589 0,11305188 ! molting cycle process GO:0022404 52 26 0,000 0,08889589 0,11299306 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,08889589 0,1129343 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,08889589 0,1128756 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,08889589 0,11281697 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,08889589 0,11275839 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,08889589 0,11269988 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,08889589 0,11264142 ! digestive system process GO:0022600 49 26 0,000 0,08889589 0,11258303 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,08889589 0,11252469 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,08889589 0,11246642 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,08889589 0,11240821 ! osteoblast differentiation GO:0001649 63 26 0,000 0,08889589 0,11235006 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,08889589 0,11229196 ! neural crest cell development GO:0014032 59 26 0,000 0,08889589 0,11223393 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,08889589 0,11217596 ! negative regulation of cell development GO:0010721 83 26 0,000 0,08889589 0,11211805 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,08889589 0,1120602 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,08889589 0,1120024 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,08889589 0,11194467 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,08889589 0,111887 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,08889589 0,11182938 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,08889589 0,11177183 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,08889589 0,11171433 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,08889589 0,11165689 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,08889589 0,11159952 ! blastocyst development GO:0001824 50 26 0,000 0,08889589 0,1115422 ! telomere organization GO:0032200 46 26 0,000 0,08889589 0,11148494 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,08889589 0,11142774 ! neural tube closure GO:0001843 58 26 0,000 0,08889589 0,11137059 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,08889589 0,11131351 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,08889589 0,11125649 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,08889589 0,11119952 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,09215368 0,11521568 ! embryonic pattern specification GO:0009880 49 27 0,000 0,09215368 0,11515675 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,09215368 0,11509787 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,09215368 0,11503906 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,09215368 0,11498031 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,09215368 0,11492161 ! iron ion transport GO:0006826 65 27 0,000 0,09215368 0,11486298 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,09215368 0,11480441 ! superoxide metabolic process GO:0006801 41 27 0,000 0,09215368 0,11474589 ! tube lumen formation GO:0035148 59 27 0,000 0,09215368 0,11468744 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,09215368 0,11462904 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,09215368 0,11457071 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,09215368 0,11451243 ! response to starvation GO:0042594 47 27 0,000 0,09215368 0,11445422 ! response to toxin GO:0009636 49 27 0,000 0,09215368 0,11439606 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,09215368 0,11433796 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,09215368 0,11427992 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,09215368 0,11422194 ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,09215368 0,11416402 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,09539991 0,11812569 ! neuron fate commitment GO:0048663 52 28 0,000 0,09539991 0,11806585 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,09539991 0,11800607 ! vesicle docking GO:0048278 55 28 0,000 0,09539991 0,11794635 ! circadian rhythm GO:0007623 56 28 0,000 0,09539991 0,11788669 ! dendrite development GO:0016358 67 28 0,000 0,09539991 0,11782709 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,09539991 0,11776756 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,09539991 0,11770808 ! sperm motility GO:0030317 37 28 0,000 0,09539991 0,11764866 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,09539991 0,1175893 ! base-excision repair GO:0006284 41 28 0,000 0,09539991 0,11753 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,09539991 0,11747076 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,09539991 0,11741158 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,09539991 0,11735246 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,09539991 0,1172934 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,09539991 0,1172344 ! glutathione metabolic process GO:0006749 42 28 0,000 0,09539991 0,11717546 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,09539991 0,11711658 ! lipid oxidation GO:0034440 48 28 0,000 0,09539991 0,11705776 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,09539991 0,11699899 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,09539991 0,11694029 ! translational initiation GO:0006413 66 29 0,000 0,09863463 0,12084474 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,09863463 0,12078416 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,09863463 0,12072365 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,09863463 0,1206632 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,09863463 0,12060281 ! autophagy GO:0006914 47 29 0,000 0,09863463 0,12054247 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,09863463 0,1204822 ! primary neural tube formation GO:0014020 61 29 0,000 0,09863463 0,12042199 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,09863463 0,12036184 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,09863463 0,12030175 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,09863463 0,12024172 ! synaptogenesis GO:0007416 46 29 0,000 0,09863463 0,12018175 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,09863463 0,12012184 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,09863463 0,12006199 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,09863463 0,12000219 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,10185787 0,12386201 ! phenol metabolic process GO:0018958 56 30 0,000 0,10185787 0,12380039 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,10185787 0,12373883 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,10185787 0,12367733 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,10185787 0,12361589 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,10185787 0,12355451 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,10185787 0,12349319 ! acute-phase response GO:0006953 50 30 0,000 0,10185787 0,12343194 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,10185787 0,12337074 ! myofibril assembly GO:0030239 50 30 0,000 0,10185787 0,12330961 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,10185787 0,12324853 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,10185787 0,12318752 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,10185787 0,12312656 ! cell fate determination GO:0001709 64 30 0,000 0,10185787 0,12306567 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,10185787 0,12300484 ! phospholipid transport GO:0015914 65 30 0,000 0,10185787 0,12294406 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,10185787 0,12288335 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,10185787 0,1228227 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,10185787 0,1227621 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,10185787 0,12270157 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,10185787 0,1226411 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,10185787 0,12258068 ! regulation of coagulation GO:0050818 52 30 0,000 0,10185787 0,12252033 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,10506968 0,12632147 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,10506968 0,12625933 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,10506968 0,12619726 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,10506968 0,12613525 ! cell junction assembly GO:0034329 85 31 0,000 0,10506968 0,12607329 ! regulation of innate immune response GO:0045088 57 31 0,000 0,10506968 0,1260114 ! ovulation cycle process GO:0022602 55 31 0,000 0,10506968 0,12594957 ! peptide transport GO:0015833 60 31 0,000 0,10506968 0,1258878 ! male gonad development GO:0008584 56 31 0,000 0,10506968 0,12582609 ! iron ion homeostasis GO:0055072 60 31 0,000 0,10506968 0,12576444 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,10506968 0,12570285 ! detection of light stimulus GO:0009583 44 31 0,000 0,10506968 0,12564132 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,10506968 0,12557986 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,10506968 0,12551845 ! natural killer cell activation GO:0030101 50 31 0,000 0,10506968 0,1254571 ! ensheathment of neurons GO:0007272 64 31 0,000 0,10506968 0,12539581 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,10506968 0,12533458 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,10506968 0,12527341 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,10506968 0,1252123 ! eye morphogenesis GO:0048592 65 31 0,000 0,10506968 0,12515125 ! response to heat GO:0009408 54 31 0,000 0,10506968 0,12509026 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,10506968 0,12502933 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,10827009 0,12877499 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,10827009 0,12871232 ! collagen metabolic process GO:0032963 49 32 0,000 0,10827009 0,12864972 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,10827009 0,12858718 ! spindle organization GO:0007051 50 32 0,000 0,10827009 0,1285247 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,10827009 0,12846228 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,10827009 0,12839991 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,10827009 0,12833762 ! muscle cell development GO:0055001 52 32 0,000 0,10827009 0,12827538 ! mesoderm formation GO:0001707 73 32 0,000 0,10827009 0,1282132 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,10827009 0,12815108 ! ovulation cycle GO:0042698 57 32 0,000 0,10827009 0,12808902 ! peripheral nervous system development GO:0007422 68 32 0,000 0,10827009 0,12802702 ! BMP signaling pathway GO:0030509 71 32 0,000 0,10827009 0,12796508 ! hindbrain development GO:0030902 65 32 0,000 0,10827009 0,1279032 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,10827009 0,12784138 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,10827009 0,12777963 ! gene silencing GO:0016458 71 32 0,000 0,10827009 0,12771793 ! regulation of pH GO:0006885 56 33 0,000 0,11145914 0,13141635 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,11145914 0,13135296 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,11145914 0,13128963 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,11145914 0,13122635 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,11145914 0,13116314 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,11145914 0,13109999 ! response to ionizing radiation GO:0010212 74 33 0,000 0,11145914 0,1310369 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,11145914 0,13097387 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,11145914 0,13091091 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,11145914 0,130848 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,11145914 0,13078515 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,11145914 0,13072236 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,11145914 0,13065964 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,11145914 0,13059697 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,11463688 0,13425594 ! glial cell differentiation GO:0010001 67 34 0,000 0,11463688 0,13419162 ! post-embryonic development GO:0009791 76 34 0,000 0,11463688 0,13412735 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,11463688 0,13406314 ! cholesterol transport GO:0030301 62 34 0,000 0,11463688 0,133999 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,11463688 0,13393491 ! spliceosome assembly GO:0000245 75 34 0,000 0,11463688 0,13387089 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,11463688 0,13380693 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,11463688 0,13374303 ! formation of primary germ layer GO:0001704 76 34 0,000 0,11463688 0,13367919 ! cell fate specification GO:0001708 56 34 0,000 0,11463688 0,13361541 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,11463688 0,13355169 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,11463688 0,13348804 ! adult locomotory behavior GO:0008344 62 34 0,000 0,11463688 0,13342444 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,11780334 0,13704456 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,11780334 0,13697933 ! negative regulation of secretion GO:0051048 68 35 0,000 0,11780334 0,13691416 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,11780334 0,13684906 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,11780334 0,13678402 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,11780334 0,13671904 ! membrane docking GO:0022406 69 35 0,000 0,11780334 0,13665412 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,11780334 0,13658926 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,11780334 0,13652446 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,11780334 0,13645973 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,11780334 0,13639506 ! ceramide metabolic process GO:0006672 72 35 0,000 0,11780334 0,13633045 ! telencephalon development GO:0021537 81 35 0,000 0,11780334 0,1362659 ! sterol transport GO:0015918 63 35 0,000 0,11780334 0,13620141 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,11780334 0,13613698 ! placenta development GO:0001890 53 35 0,000 0,11780334 0,13607261 ! vesicle localization GO:0051648 70 35 0,000 0,11780334 0,1360083 ! regulation of muscle development GO:0048634 82 36 0,000 0,12095857 0,13958516 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,12095857 0,13951926 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,12095857 0,13945342 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,12095857 0,13938764 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,12095857 0,13932192 ! positive regulation of cell development GO:0010720 85 36 0,000 0,12095857 0,13925626 ! protein targeting to membrane GO:0006612 75 36 0,000 0,12095857 0,13919067 ! regulation of proteolysis GO:0030162 77 36 0,000 0,12095857 0,13912514 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,12095857 0,13905967 ! aerobic respiration GO:0009060 56 36 0,000 0,12095857 0,13899426 ! cytokine production GO:0001816 68 36 0,000 0,12095857 0,13892891 ! embryonic organ development GO:0048568 67 36 0,000 0,12095857 0,13886362 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,12095857 0,1387984 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,12095857 0,13873324 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,1241026 0,14227248 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,1241026 0,14220575 ! sister chromatid segregation GO:0000819 65 37 0,000 0,1241026 0,14213908 ! odontogenesis GO:0042476 74 37 0,000 0,1241026 0,14207247 ! actomyosin structure organization GO:0031032 68 37 0,000 0,1241026 0,14200593 ! cell junction organization GO:0034330 96 37 0,000 0,1241026 0,14193945 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,1241026 0,14187303 ! female gonad development GO:0008585 71 37 0,000 0,1241026 0,14180667 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,1241026 0,14174037 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,1241026 0,14167414 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,1241026 0,14160797 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,12723548 0,14511497 ! meiosis I GO:0007127 74 38 0,000 0,12723548 0,14504726 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,12723548 0,1449796 ! organic anion transport GO:0015711 82 38 0,000 0,12723548 0,14491202 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,12723548 0,14484449 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,12723548 0,14477702 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,12723548 0,14470962 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,12723548 0,14464229 ! spermatid development GO:0007286 69 38 0,000 0,12723548 0,14457501 ! glycogen metabolic process GO:0005977 63 38 0,000 0,12723548 0,1445078 ! pigment metabolic process GO:0042440 87 38 0,000 0,12723548 0,14444065 ! neural tube formation GO:0001841 79 38 0,000 0,12723548 0,14437356 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,13035723 0,14784713 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,13035723 0,14777853 ! negative regulation of binding GO:0051100 71 39 0,000 0,13035723 0,14770998 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,13035723 0,1476415 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,13035723 0,14757309 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,13035723 0,14750474 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,13035723 0,14743645 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,13035723 0,14736822 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,13035723 0,14730006 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,13035723 0,14723196 ! glucan metabolic process GO:0044042 64 39 0,000 0,13035723 0,14716392 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,13346791 0,15060606 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,13346791 0,15053652 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,13346791 0,15046706 ! learning GO:0007612 82 40 0,000 0,13346791 0,15039765 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,13346791 0,15032831 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,13346791 0,15025904 ! lipid homeostasis GO:0055088 75 40 0,000 0,13346791 0,15018983 ! mismatch repair GO:0006298 58 40 0,000 0,13346791 0,15012068 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,13346791 0,15005159 ! RNA export from nucleus GO:0006405 61 41 0,000 0,13656755 0,15346574 ! mRNA catabolic process GO:0006402 79 41 0,000 0,13656755 0,15339519 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,13656755 0,15332469 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,13656755 0,15325426 ! gliogenesis GO:0042063 91 41 0,000 0,13656755 0,1531839 ! feeding behavior GO:0007631 69 41 0,000 0,13656755 0,1531136 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,13656755 0,15304336 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,13656755 0,15297319 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,13656755 0,15290308 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,13656755 0,15283304 ! spermatid differentiation GO:0048515 73 41 0,000 0,13656755 0,15276306 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,13656755 0,15269315 ! RNA modification GO:0009451 64 41 0,000 0,13656755 0,1526233 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,13965619 0,15600369 ! ear morphogenesis GO:0042471 64 42 0,000 0,13965619 0,15593239 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,13965619 0,15586116 ! T cell differentiation GO:0030217 93 42 0,000 0,13965619 0,15578999 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,13965619 0,15571888 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,13965619 0,15564784 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,13965619 0,15557687 ! regulation of protein secretion GO:0050708 77 42 0,000 0,13965619 0,15550596 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,13965619 0,15543511 ! cytokinesis GO:0000910 84 42 0,000 0,13965619 0,15536433 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,13965619 0,15529361 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,14273387 0,15864369 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,14273387 0,15857155 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,14273387 0,15849947 ! regulation of tube size GO:0035150 76 43 0,000 0,14273387 0,15842746 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,14273387 0,15835551 ! glucose transport GO:0015758 66 43 0,000 0,14273387 0,15828363 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,14273387 0,15821181 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,14273387 0,15814006 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,14273387 0,15806837 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,14273387 0,15799675 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,14273387 0,1579252 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,14273387 0,15785371 ! ion transmembrane transport GO:0034220 79 43 0,000 0,14273387 0,15778228 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,14273387 0,15771092 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,14580062 0,16102663 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,14580062 0,16095387 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,14580062 0,16088117 ! hexose transport GO:0008645 68 44 0,000 0,14580062 0,16080854 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,14580062 0,16073597 ! striated muscle contraction GO:0006941 85 44 0,000 0,14580062 0,16066347 ! phagocytosis GO:0006909 105 44 0,000 0,14580062 0,16059103 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,14580062 0,16051866 ! double-strand break repair GO:0006302 85 44 0,000 0,14580062 0,16044636 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,14885649 0,16373543 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,14885649 0,16366175 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,14885649 0,16358812 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,14885649 0,16351457 ! B cell differentiation GO:0030183 124 45 0,000 0,14885649 0,16344108 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,14885649 0,16336765 ! female gamete generation GO:0007292 71 45 0,000 0,14885649 0,1632943 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,14885649 0,163221 ! polyol metabolic process GO:0019751 77 45 0,000 0,14885649 0,16314778 ! developmental growth GO:0048589 88 45 0,000 0,14885649 0,16307462 ! maintenance of location in cell GO:0051651 101 45 0,000 0,14885649 0,16300152 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,15190151 0,16626137 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,15190151 0,16618692 ! glycolysis GO:0006096 71 46 0,000 0,15190151 0,16611253 ! leukocyte migration GO:0050900 75 46 0,000 0,15190151 0,1660382 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,15190151 0,16596395 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,15190151 0,16588976 ! cell growth GO:0016049 90 46 0,000 0,15190151 0,16581563 ! neural tube development GO:0021915 91 47 0,000 0,15493572 0,16905224 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,15493572 0,16897677 ! positive regulation of defense response GO:0031349 88 48 0,000 0,15795917 0,17219734 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,15795917 0,17212054 ! mitochondrial transport GO:0006839 94 48 0,000 0,15795917 0,1720438 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,15795917 0,17196713 ! cellular component disassembly GO:0022411 89 48 0,000 0,15795917 0,17189053 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,15795917 0,171814 ! endosome transport GO:0016197 127 48 0,000 0,15795917 0,17173754 ! male sex differentiation GO:0046661 93 48 0,000 0,15795917 0,17166114 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,15795917 0,17158481 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,15795917 0,17150855 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,15795917 0,17143236 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,16097188 0,17462446 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,16097188 0,17454696 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,16097188 0,17446952 ! JNK cascade GO:0007254 106 49 0,000 0,16097188 0,17439215 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,16097188 0,17431485 ! regulation of action potential GO:0001508 102 50 0,000 0,16397389 0,17748703 ! regulation of ion transport GO:0043269 86 50 0,000 0,16397389 0,17740842 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,16397389 0,17732989 ! endocrine system development GO:0035270 109 50 0,000 0,16397389 0,17725142 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,16397389 0,17717303 ! regulation of ossification GO:0030278 123 50 0,000 0,16397389 0,1770947 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,16397389 0,17701645 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,16397389 0,17693826 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,16397389 0,17686014 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,16397389 0,17678209 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,16696525 0,17992771 ! peptide metabolic process GO:0006518 80 51 0,000 0,16696525 0,17984837 ! response to temperature stimulus GO:0009266 84 51 0,000 0,16696525 0,17976911 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,16696525 0,17968992 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,16696525 0,17961079 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,16994599 0,18273682 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,16994599 0,18265643 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,16994599 0,1825761 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,16994599 0,18249585 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,16994599 0,18241567 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,16994599 0,18233556 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,17291615 0,18544081 ! inner ear development GO:0048839 89 53 0,000 0,17291615 0,18535944 ! chromatin remodeling GO:0006338 122 53 0,000 0,17291615 0,18527814 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,17291615 0,18519691 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,17291615 0,18511576 ! vesicle organization GO:0016050 127 53 0,000 0,17291615 0,18503467 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,17291615 0,18495366 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 0,000 0,17291615 0,18487272 ! synapse organization GO:0050808 102 53 0,000 0,17291615 0,18479184 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,17587576 0,18787254 ! neuromuscular process GO:0050905 107 54 0,000 0,17587576 0,18779043 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,17587576 0,18770838 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,17587576 0,18762642 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,17587576 0,18754452 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,17587576 0,18746269 ! RNA catabolic process GO:0006401 103 55 0,000 0,17882487 0,19052297 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,17882487 0,19043991 ! cell recognition GO:0008037 98 55 0,000 0,17882487 0,19035693 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,17882487 0,19027402 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,17882487 0,19019119 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,18176351 0,19323248 ! glucose catabolic process GO:0006007 88 56 0,000 0,18176351 0,19314843 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,18176351 0,19306445 ! chloride transport GO:0006821 102 57 0,000 0,18469171 0,19608946 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,18469171 0,19600428 ! regulation of actin filament length GO:0030832 118 58 0,000 0,18760951 0,19901435 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,18760951 0,19892797 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,18760951 0,19884167 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,18760951 0,19875544 ! gastrulation GO:0007369 122 58 0,000 0,18760951 0,19866929 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,18760951 0,19858321 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,18760951 0,1984972 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,19341408 0,20455004 ! DNA catabolic process GO:0006308 94 60 0,000 0,19341408 0,20446153 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,19341408 0,2043731 ! adult behavior GO:0030534 104 60 0,000 0,19341408 0,20428474 ! regulation of cellular component size GO:0032535 125 61 0,000 0,19630091 0,20724422 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,19630091 0,2071547 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,19630091 0,20706526 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,19630091 0,20697589 ! regulation of heart contraction GO:0008016 123 61 0,000 0,19630091 0,2068866 ! camera-type eye development GO:0043010 126 61 0,000 0,19630091 0,20679738 ! proton transport GO:0015992 117 61 0,000 0,19630091 0,20670825 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,1991775 0,20964697 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,1991775 0,20955669 ! tRNA processing GO:0008033 102 62 0,000 0,1991775 0,20946648 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,20204386 0,21238948 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,20204386 0,21229813 ! hydrogen transport GO:0006818 121 64 0,000 0,20490005 0,21520672 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,20490005 0,21511424 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,2077461 0,21800847 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,2077461 0,21791486 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,2077461 0,21782134 GO:0048609|reproductive process in a multicellular organism, ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,2077461 0,21772789 ! ear development GO:0043583 114 66 0,000 0,21058204 0,22060545 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,21058204 0,22051089 ! gonad development GO:0008406 115 66 0,000 0,21058204 0,22041642 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,2134079 0,22327859 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,2134079 0,22318301 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,2134079 0,22308751 ! secondary metabolic process GO:0019748 125 67 0,000 0,2134079 0,22299209 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,21622373 0,22583778 ! hexose catabolic process GO:0019320 113 68 0,000 0,21622373 0,22574127 ! extracellular matrix organization GO:0030198 146 68 0,000 0,21622373 0,22564484 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,21622373 0,2255485 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,21622373 0,22545223 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,21622373 0,22535605 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,21622373 0,22525995 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,21902956 0,22808577 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,21902956 0,22798859 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,21902956 0,22789149 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,21902956 0,22779447 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,21902956 0,22769754 ! single fertilization GO:0007338 83 69 0,000 0,21902956 0,22760069 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,22182542 0,23040796 ! cell redox homeostasis GO:0045454 114 70 0,000 0,22182542 0,23031003 ! activation of immune response GO:0002253 120 70 0,000 0,22182542 0,2302122 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,22461136 0,23300448 ! appendage morphogenesis GO:0035107 150 72 0,000 0,22738739 0,23578413 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,22738739 0,23568409 ! actin filament organization GO:0007015 167 72 0,000 0,22738739 0,23558414 ! B cell activation GO:0042113 179 72 0,000 0,22738739 0,23548427 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,22738739 0,23538449 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,22738739 0,2352848 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,22738739 0,23518518 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,22738739 0,23508566 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,22738739 0,23498621 ! appendage development GO:0048736 151 73 0,000 0,23015357 0,23774426 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,23015357 0,23764377 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,23015357 0,23754338 ! regulation of immune effector process GO:0002697 156 73 0,000 0,23015357 0,23744306 ! acute inflammatory response GO:0002526 118 74 0,000 0,23290992 0,24018528 ! amino acid transport GO:0006865 148 74 0,000 0,23290992 0,24008394 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,23290992 0,23998268 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,23290992 0,23988151 ! transition metal ion transport GO:0000041 143 75 0,000 0,23565648 0,242608 ! reproductive structure development GO:0048608 131 75 0,000 0,23565648 0,2425058 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,23565648 0,2424037 ! eye development GO:0001654 155 75 0,000 0,23565648 0,24230167 ! rhythmic process GO:0048511 142 75 0,000 0,23565648 0,24219974 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,23839328 0,2449095 ! learning or memory GO:0007611 161 76 0,000 0,23839328 0,24480655 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,23839328 0,24470369 ! amine catabolic process GO:0009310 136 77 0,000 0,24112036 0,24739901 ! neurotransmitter transport GO:0006836 142 77 0,000 0,24112036 0,24729515 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,24112036 0,24719137 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,24112036 0,24708768 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,24383775 0,24976756 ! fertilization GO:0009566 99 78 0,000 0,24383775 0,24966288 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,24383775 0,24955829 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,24654549 0,25222388 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,24654549 0,2521183 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,24654549 0,25201282 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,24654549 0,25190741 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,24654549 0,2518021 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,24924361 0,25445137 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,24924361 0,25434508 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,24924361 0,25423888 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,24924361 0,25413278 ! meiosis GO:0007126 143 81 0,000 0,25193214 0,25676688 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 144 82 0,000 0,25461112 0,25938906 ! exocytosis GO:0006887 153 83 0,000 0,25728058 0,26199935 ! inorganic anion transport GO:0015698 156 83 0,000 0,25728058 0,26189019 ! digestion GO:0007586 130 84 0,000 0,25994055 0,26448762 ! regulation of ligase activity GO:0051340 147 84 0,000 0,25994055 0,2643775 ! negative regulation of transport GO:0051051 164 85 0,000 0,26259107 0,26696213 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,26259107 0,26685108 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,26259107 0,26674012 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,26523218 0,26931098 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,2678639 0,27187017 ! mitochondrion organization GO:0007005 159 87 0,000 0,2678639 0,27175727 ! alcohol catabolic process GO:0046164 142 87 0,000 0,2678639 0,27164446 ! nucleosome assembly GO:0006334 126 87 0,000 0,2678639 0,27153174 ! cellular respiration GO:0045333 143 88 0,000 0,27048627 0,27407629 ! amine biosynthetic process GO:0009309 146 88 0,000 0,27048627 0,27396266 ! sensory perception of smell GO:0007608 117 88 0,000 0,27048627 0,27384913 ! chromatin assembly GO:0031497 128 88 0,000 0,27048627 0,27373569 ! cellular defense response GO:0006968 123 89 0,000 0,27309931 0,27626568 ! regulation of neurological system process GO:0031644 175 89 0,000 0,27309931 0,27615133 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,27570308 0,27866885 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,27570308 0,2785536 ! response to unfolded protein GO:0006986 139 90 0,000 0,27570308 0,27843845 ! gland development GO:0048732 220 91 0,000 0,27829758 0,28094256 ! defense response to bacterium GO:0042742 112 91 0,000 0,27829758 0,28082652 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,28088287 0,28331827 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,28088287 0,28320134 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,28345897 0,2856808 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,28345897 0,285563 ! vitamin metabolic process GO:0006766 153 93 0,000 0,28345897 0,28544529 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,28602591 0,28791154 ! female pregnancy GO:0007565 166 94 0,000 0,28602591 0,28779296 ! sterol metabolic process GO:0016125 166 94 0,000 0,28602591 0,28767448 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,28602591 0,28755609 ! regulation of membrane potential GO:0042391 179 94 0,000 0,28602591 0,28743781 ! regulation of defense response GO:0031347 171 95 0,000 0,28858373 0,28988901 ! nucleosome organization GO:0034728 143 95 0,000 0,28858373 0,28976986 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,28858373 0,28965081 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,28858373 0,28953185 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,28858373 0,289413 ! sex differentiation GO:0007548 171 96 0,000 0,29113246 0,29184924 ! response to protein stimulus GO:0051789 158 96 0,000 0,29113246 0,29172954 ! regulation of T cell activation GO:0050863 175 96 0,000 0,29113246 0,29160992 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,29367213 0,2940332 ! forebrain development GO:0030900 210 98 0,000 0,29620277 0,29644546 ! positive regulation of immune response GO:0050778 175 100 0,000 0,3012371 0,30136046 ! hormone metabolic process GO:0042445 171 100 0,000 0,3012371 0,3012371