pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1125-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! lung development GO:0030324 144 67 6,000 1,528E-10 3,678E-07 ! auditory receptor cell differentiation GO:0042491 32 16 4,000 2,005E-10 2,413E-07 ! respiratory tube development GO:0030323 150 70 6,000 2,096E-10 1,681E-07 ! respiratory system development GO:0060541 153 72 6,000 2,567E-10 1,544E-07 ! inner ear receptor cell differentiation GO:0060113 37 20 4,000 7,07E-10 3,402E-07 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 4,000 9,263E-10 3,714E-07 ! mechanoreceptor differentiation GO:0042490 40 22 4,000 1,197E-09 4,113E-07 ! nucleosome disassembly GO:0006337 14 8 3,000 1,555E-09 4,677E-07 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! regulation of oxidoreductase activity GO:0051341 46 24 4,000 1,925E-09 5,146E-07 ! regulation of histone modification GO:0031056 12 9 3,000 2,794E-09 6,723E-07 ! positive regulation of oxidoreductase activity GO:0051353 22 15 3,000 2,997E-08 6,555E-06 ! inner ear development GO:0048839 79 50 4,000 9,176E-08 1,84E-05 ! positive regulation of glycolysis GO:0045821 14 5 2,000 1,049E-07 1,941E-05 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 1,055E-07 1,813E-05 ! cellular macromolecular complex disassembly GO:0034623 43 21 3,000 1,301E-07 2,087E-05 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 3,000 2,731E-07 4,107E-05 ! ear development GO:0043583 103 62 4,000 2,746E-07 3,886E-05 ! macromolecular complex disassembly GO:0032984 53 26 3,000 3,223E-07 4,307E-05 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 3,223E-07 4,081E-05 ! N-terminal protein amino acid acetylation GO:0006474 13 7 2,000 3,66E-07 4,403E-05 ! regulation of chromosome organization GO:0033044 42 27 3,000 3,777E-07 4,327E-05 ! negative regulation of protein modification process GO:0031400 60 28 3,000 4,399E-07 4,811E-05 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 4,399E-07 4,601E-05 ! protein oligomerization GO:0051259 139 78 4,000 8,715E-07 8,736E-05 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 8,755E-07 8,426E-05 ! regulation of glycolysis GO:0006110 21 9 2,000 8,755E-07 8,102E-05 ! protein heterooligomerization GO:0051291 16 9 2,000 8,755E-07 7,802E-05 ! gas homeostasis GO:0033483 16 9 2,000 8,755E-07 7,523E-05 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 2,000 1,249E-06 1,036E-04 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 1,714E-06 1,375E-04 ! peptide or protein amino-terminal blocking GO:0018409 21 11 2,000 1,714E-06 1,331E-04 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 2,282E-06 1,716E-04 ! histone acetylation GO:0016573 26 12 2,000 2,282E-06 1,664E-04 ! peptidyl-lysine modification GO:0018205 21 12 2,000 2,282E-06 1,615E-04 ! Golgi vesicle transport GO:0048193 207 99 4,000 2,848E-06 1,958E-04 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 2,000 2,962E-06 1,98E-04 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 2,000 2,962E-06 1,926E-04 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 3,764E-06 2,383E-04 ! cellular component disassembly GO:0022411 86 48 3,000 4,043E-06 2,494E-04 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 5,772E-06 3,472E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 6,998E-06 4,106E-04 ! positive regulation of cell migration GO:0030335 126 57 3,000 8,084E-06 4,631E-04 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 8,384E-06 4,691E-04 ! protein amino acid acetylation GO:0006473 39 20 2,000 1,168E-05 6,384E-04 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 1,168E-05 6,242E-04 GO:0010675|regulation of cellular carbohydrate metabolic process, ! positive regulation of cell motion GO:0051272 146 64 3,000 1,285E-05 6,722E-04 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 2,06E-05 1,054E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 2,638E-05 1,322E-03 ! negative regulation of organelle organization GO:0010639 161 78 3,000 2,819E-05 1,384E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 2,962E-05 1,426E-03 ! protein amino acid acylation GO:0043543 55 27 2,000 2,962E-05 1,398E-03 ! response to hypoxia GO:0001666 171 81 3,000 3,271E-05 1,514E-03 ! response to oxygen levels GO:0070482 176 83 3,000 3,601E-05 1,635E-03 ! nucleosome assembly GO:0006334 122 85 3,000 3,955E-05 1,762E-03 ! chromatin assembly GO:0031497 124 86 3,000 4,141E-05 1,811E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 4,854E-05 2,086E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 4,854E-05 2,049E-03 ! parathyroid gland development GO:0060017 13 5 1,000 4,854E-05 2,014E-03 ! microvillus organization GO:0032528 7 5 1,000 4,854E-05 1,98E-03 GO:0030033|microvillus assembly, ! mRNA transcription GO:0009299 9 5 1,000 4,854E-05 1,947E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,854E-05 1,915E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 4,854E-05 1,884E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 4,854E-05 1,854E-03 ! protein-DNA complex assembly GO:0065004 130 90 3,000 4,949E-05 1,861E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 4,984E-05 1,845E-03 ! nucleosome organization GO:0034728 138 92 3,000 5,394E-05 1,966E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 5,627E-05 2,021E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 7,271E-05 2,573E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 7,271E-05 2,535E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 7,271E-05 2,499E-03 ! male sex determination GO:0030238 15 6 1,000 7,271E-05 2,464E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 7,271E-05 2,43E-03 ! tissue remodeling GO:0048771 76 37 2,000 7,745E-05 2,553E-03 ! carbohydrate homeostasis GO:0033500 53 38 2,000 8,396E-05 2,73E-03 GO:0042593|glucose homeostasis, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 1,016E-04 3,261E-03 ! vesicle fusion GO:0006906 17 7 1,000 1,016E-04 3,218E-03 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 1,016E-04 3,176E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 1,016E-04 3,135E-03 ! oxygen homeostasis GO:0032364 12 7 1,000 1,016E-04 3,096E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,016E-04 3,057E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 1,016E-04 3,019E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 1,016E-04 2,983E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,353E-04 3,923E-03 ! hemoglobin metabolic process GO:0020027 13 8 1,000 1,353E-04 3,876E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,353E-04 3,831E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 1,492E-04 4,173E-03 ! protein homooligomerization GO:0051260 76 47 2,000 1,591E-04 4,4E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,694E-04 4,632E-03 ! Notch signaling pathway GO:0007219 96 48 2,000 1,694E-04 4,58E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 1,738E-04 4,645E-03 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 1,738E-04 4,594E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 1,738E-04 4,544E-03 GO:0010469|regulation of receptor activity, ! induction of an organ GO:0001759 14 9 1,000 1,738E-04 4,495E-03 ! S phase GO:0051320 9 9 1,000 1,738E-04 4,447E-03 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,738E-04 4,401E-03 ! histone modification GO:0016570 91 50 2,000 1,914E-04 4,796E-03 ! covalent chromatin modification GO:0016569 101 52 2,000 2,151E-04 5,336E-03 ! glucan biosynthetic process GO:0009250 14 10 1,000 2,169E-04 5,325E-03 GO:0005978|glycogen biosynthetic process, ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 2,169E-04 5,271E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,169E-04 5,218E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,169E-04 5,166E-03 ! localization within membrane GO:0051668 20 10 1,000 2,169E-04 5,116E-03 ! heart morphogenesis GO:0003007 97 55 2,000 2,541E-04 5,936E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 2,647E-04 6,124E-03 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 2,647E-04 6,065E-03 ! thymus development GO:0048538 27 11 1,000 2,647E-04 6,008E-03 ! developmental induction GO:0031128 19 11 1,000 2,647E-04 5,952E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 2,647E-04 5,897E-03 ! positive regulation of organelle organization GO:0010638 100 56 2,000 2,681E-04 5,918E-03 ! virus-host interaction GO:0019048 29 12 1,000 3,172E-04 6,938E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 3,172E-04 6,875E-03 ! gland morphogenesis GO:0022612 29 12 1,000 3,172E-04 6,814E-03 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 3,172E-04 6,753E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 3,289E-04 6,941E-03 ! regulation of chemokine production GO:0032642 18 13 1,000 3,743E-04 7,831E-03 ! lipid localization GO:0010876 28 13 1,000 3,743E-04 7,764E-03 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 3,743E-04 7,697E-03 ! embryonic placenta development GO:0001892 23 13 1,000 3,743E-04 7,632E-03 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 3,743E-04 7,568E-03 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 4,361E-04 8,743E-03 ! activation of MAPK activity GO:0000187 115 67 2,000 4,553E-04 9,053E-03 ! heterophilic cell adhesion GO:0007157 39 15 1,000 5,024E-04 9,909E-03 ! regulation of vasodilation GO:0042312 26 15 1,000 5,024E-04 9,828E-03 ! muscle maintenance GO:0046716 26 15 1,000 5,024E-04 9,749E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 5,024E-04 9,671E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 5,734E-04 0,01094888 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 5,734E-04 0,01086267 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 5,734E-04 0,01077781 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 6,489E-04 0,01210276 ! heart looping GO:0001947 30 17 1,000 6,489E-04 0,01200966 ! neural crest cell migration GO:0001755 37 17 1,000 6,489E-04 0,01191798 ! regulation of catabolic process GO:0009894 161 76 2,000 6,587E-04 0,0120058 ! memory GO:0007613 31 18 1,000 7,29E-04 0,01318715 ! cell-substrate junction assembly GO:0007044 54 18 1,000 7,29E-04 0,01308874 ! regulation of peptidase activity GO:0052547 134 79 2,000 7,374E-04 0,0131423 ! protein secretion GO:0009306 39 19 1,000 8,136E-04 0,01439278 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 8,136E-04 0,01428772 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 8,136E-04 0,01418418 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 9,027E-04 0,01562437 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 9,027E-04 0,01551276 ! inactivation of MAPK activity GO:0000188 39 21 1,000 9,962E-04 0,01699966 ! regulation of vasoconstriction GO:0019229 39 21 1,000 9,962E-04 0,01687994 ! gland development GO:0048732 206 88 2,000 1,009E-03 0,01697316 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 1,094E-03 0,01828378 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 1,094E-03 0,01815768 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,094E-03 0,01803332 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,094E-03 0,01791064 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,197E-03 0,01945593 ! leukocyte adhesion GO:0007159 50 23 1,000 1,197E-03 0,01932535 ! sex determination GO:0007530 47 23 1,000 1,197E-03 0,01919651 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 1,258E-03 0,02005125 ! vesicle docking GO:0048278 47 24 1,000 1,304E-03 0,02063646 ! membrane depolarization GO:0051899 39 24 1,000 1,304E-03 0,02050158 ! protein tetramerization GO:0051262 52 24 1,000 1,304E-03 0,02036846 ! interphase GO:0051325 213 98 2,000 1,376E-03 0,02136283 ! vasculogenesis GO:0001570 46 25 1,000 1,415E-03 0,02182444 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 1,415E-03 0,02168544 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 1,415E-03 0,02154819 ! neural crest cell development GO:0014032 54 25 1,000 1,415E-03 0,02141266 GO:0014033|neural crest cell differentiation, ! interaction with host GO:0051701 62 25 1,000 1,415E-03 0,02127883 ! somitogenesis GO:0001756 43 25 1,000 1,415E-03 0,02114667 ! regulation of blood coagulation GO:0030193 40 25 1,000 1,415E-03 0,02101613 ! skeletal muscle tissue development GO:0007519 186 99 2,000 1,417E-03 0,02091604 GO:0060538|skeletal muscle organ development, ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 1,531E-03 0,02245758 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,531E-03 0,02232147 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 1,531E-03 0,02218701 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 1,531E-03 0,02205415 ! cellular response to oxidative stress GO:0034599 39 26 1,000 1,531E-03 0,02192287 ! positive regulation of nuclear division GO:0051785 40 26 1,000 1,531E-03 0,02179315 GO:0045840|positive regulation of mitosis, ! cellular iron ion homeostasis GO:0006879 51 29 1,000 1,904E-03 0,02694832 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 1,904E-03 0,02679073 ! regulation of coagulation GO:0050818 46 29 1,000 1,904E-03 0,02663497 ! membrane docking GO:0022406 61 30 1,000 2,037E-03 0,02833186 ! cell junction assembly GO:0034329 78 30 1,000 2,037E-03 0,02816903 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 2,037E-03 0,02800807 ! collagen metabolic process GO:0032963 45 31 1,000 2,175E-03 0,0297269 ! cholesterol homeostasis GO:0042632 53 31 1,000 2,175E-03 0,02955895 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 2,175E-03 0,02939289 ! triglyceride metabolic process GO:0006641 43 31 1,000 2,175E-03 0,02922868 ! iron ion homeostasis GO:0055072 54 31 1,000 2,175E-03 0,0290663 ! cholesterol transport GO:0030301 56 32 1,000 2,316E-03 0,03078859 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 2,316E-03 0,03061943 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 2,316E-03 0,03045211 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 2,462E-03 0,03219441 ! cell fate specification GO:0001708 52 33 1,000 2,462E-03 0,03202038 ! sterol transport GO:0015918 57 33 1,000 2,462E-03 0,03184823 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 2,612E-03 0,03360959 ! mismatch repair GO:0006298 46 34 1,000 2,612E-03 0,03343082 ! placenta development GO:0001890 53 34 1,000 2,612E-03 0,03325393 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 2,612E-03 0,03307891 ! neutral lipid metabolic process GO:0006638 50 35 1,000 2,767E-03 0,03485004 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 2,767E-03 0,03466853 ! regulation of microtubule-based process GO:0032886 78 35 1,000 2,767E-03 0,0344889 ! cell junction organization GO:0034330 86 36 1,000 2,925E-03 0,03627742 ! embryonic organ development GO:0048568 57 36 1,000 2,925E-03 0,03609138 ! glycerol ether metabolic process GO:0006662 53 37 1,000 3,088E-03 0,03790476 ! glycogen metabolic process GO:0005977 61 37 1,000 3,088E-03 0,03771235 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 3,088E-03 0,03752188 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 3,255E-03 0,03935101 ! lipid homeostasis GO:0055088 67 38 1,000 3,255E-03 0,03915425 ! glucan metabolic process GO:0044042 62 38 1,000 3,255E-03 0,03895946 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 3,426E-03 0,04080361 ! organic ether metabolic process GO:0018904 55 39 1,000 3,426E-03 0,04060261 ! segmentation GO:0035282 67 39 1,000 3,426E-03 0,04040358 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 3,601E-03 0,04226207 ! mesenchymal cell development GO:0014031 87 40 1,000 3,601E-03 0,04205691 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 3,963E-03 0,04606803 GO:0090047|positive regulation of transcription regulator activity, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 3,963E-03 0,04584655 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 3,963E-03 0,04562719 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 4,151E-03 0,04755693 ! energy reserve metabolic process GO:0006112 74 43 1,000 4,151E-03 0,04733155 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 4,151E-03 0,04710828 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 4,538E-03 0,05125761 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 4,538E-03 0,05101809 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 4,538E-03 0,0507808 ! cell growth GO:0016049 84 45 1,000 4,538E-03 0,0505457 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 4,737E-03 0,05252454 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 4,737E-03 0,0522836 ! response to insulin stimulus GO:0032868 95 46 1,000 4,737E-03 0,05204486 ! positive regulation of protein transport GO:0051222 72 46 1,000 4,737E-03 0,0518083 ! positive regulation of DNA binding GO:0043388 73 47 1,000 4,941E-03 0,05378907 ! JNK cascade GO:0007254 91 47 1,000 4,941E-03 0,05354677 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 5,36E-03 0,05782575 ! endocrine system development GO:0035270 104 49 1,000 5,36E-03 0,05756759 ! positive regulation of cytokine production GO:0001819 86 50 1,000 5,575E-03 0,05961446 ! positive regulation of binding GO:0051099 78 51 1,000 5,794E-03 0,06168494 ! chromatin remodeling GO:0006338 109 51 1,000 5,794E-03 0,0614132 ! vesicle organization GO:0016050 107 51 1,000 5,794E-03 0,06114384 ! regulation of angiogenesis GO:0045765 114 52 1,000 6,017E-03 0,06322151 ! regulation of muscle contraction GO:0006937 81 52 1,000 6,017E-03 0,06294663 ! membrane fusion GO:0006944 110 52 1,000 6,017E-03 0,06267414 ! positive regulation of growth GO:0045927 90 52 1,000 6,017E-03 0,06240399 ! cartilage development GO:0051216 90 52 1,000 6,017E-03 0,06213616 ! regulation of protein polymerization GO:0032271 103 53 1,000 6,244E-03 0,06420513 ! response to UV GO:0009411 104 53 1,000 6,244E-03 0,06393192 ! activation of phospholipase C activity GO:0007202 103 54 1,000 6,475E-03 0,06601515 GO:0010863|positive regulation of phospholipase C activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 6,71E-03 0,06811988 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 6,71E-03 0,06783366 ! regulation of DNA replication GO:0006275 101 56 1,000 6,949E-03 0,06995172 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 7,191E-03 0,07209036 ! regulation of phospholipase activity GO:0010517 106 57 1,000 7,191E-03 0,07179123 ! regulation of intracellular transport GO:0032386 101 57 1,000 7,191E-03 0,07149457 ! positive regulation of lipase activity GO:0060193 108 58 1,000 7,437E-03 0,07363803 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 7,687E-03 0,07580117 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 7,941E-03 0,07798357 ! regulation of protein complex assembly GO:0043254 117 61 1,000 8,198E-03 0,08018484 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 8,198E-03 0,07986021 ! viral reproductive process GO:0022415 126 62 1,000 8,46E-03 0,0820723 ! regulation of homeostatic process GO:0032844 134 62 1,000 8,46E-03 0,08174269 ! regulation of mitosis GO:0007088 105 63 1,000 8,725E-03 0,08396523 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 8,725E-03 0,08363071 ! cell redox homeostasis GO:0045454 102 64 1,000 8,993E-03 0,08586336 ! cell projection assembly GO:0030031 120 66 1,000 9,541E-03 0,09073739 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 9,821E-03 0,09302838 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 9,821E-03 0,09266356 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,01010414 0,09496317 ! viral reproduction GO:0016032 134 68 1,000 0,01010414 0,09459367 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01010414 0,09422703 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,01097529 0,10195577 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01107464 0,10248299 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01107464 0,10209033 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01107464 0,10170067 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01107464 0,10131398 ! neuron fate determination GO:0048664 7 5 0,000 0,01107464 0,10093021 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01107464 0,10054935 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01107464 0,10017134 ! polyol transport GO:0015791 12 5 0,000 0,01107464 0,09979617 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01107464 0,09942379 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01107464 0,09905419 ! response to superoxide GO:0000303 10 5 0,000 0,01107464 0,09868732 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01107464 0,09832316 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01107464 0,09796168 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01107464 0,09760285 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01107464 0,09724663 ! female meiosis GO:0007143 7 5 0,000 0,01107464 0,09689301 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01107464 0,09654194 ! cobalt ion transport GO:0006824 11 5 0,000 0,01107464 0,09619342 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01107464 0,0958474 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01107464 0,09550386 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01107464 0,09516277 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01107464 0,09482412 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01107464 0,09448786 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01107464 0,09415398 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01107464 0,09382245 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01107464 0,09349325 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01107464 0,09316635 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01107464 0,09284173 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01107464 0,09251936 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01107464 0,09219923 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01107464 0,0918813 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01107464 0,09156556 ! negative chemotaxis GO:0050919 14 5 0,000 0,01107464 0,09125197 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01107464 0,09094053 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01107464 0,09063121 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01107464 0,09032399 ! behavioral response to pain GO:0048266 9 5 0,000 0,01107464 0,09001884 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01107464 0,08971575 ! Notch receptor processing GO:0007220 8 5 0,000 0,01107464 0,08941469 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01107464 0,08911564 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01107464 0,08881859 ! micturition GO:0060073 9 5 0,000 0,01107464 0,08852351 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01107464 0,08823039 ! copulation GO:0007620 9 5 0,000 0,01107464 0,0879392 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01107464 0,08764992 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01107464 0,08736255 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01107464 0,08707705 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01107464 0,08679341 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01107464 0,08651161 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01107464 0,08623164 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01107464 0,08595347 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01107464 0,0856771 ! grooming behavior GO:0007625 6 5 0,000 0,01107464 0,08540249 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01107464 0,08512964 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01107464 0,08485852 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01107464 0,08458913 ! response to protozoan GO:0001562 10 5 0,000 0,01107464 0,08432145 ! lymph vessel development GO:0001945 10 5 0,000 0,01107464 0,08405545 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01107464 0,08379112 ! endochondral ossification GO:0001958 16 5 0,000 0,01107464 0,08352845 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01107464 0,08326743 ! anagen GO:0042640 6 5 0,000 0,01107464 0,08300803 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01107464 0,08275024 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01107464 0,08249405 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01107464 0,08223943 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01107464 0,08198639 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01107464 0,0817349 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01107464 0,08148494 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01107464 0,08123651 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01107464 0,08098959 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01107464 0,08074417 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01107464 0,08050023 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01107464 0,08025776 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01107464 0,08001675 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01107464 0,07977718 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01107464 0,07953903 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01107464 0,07930231 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01107464 0,07906699 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01107464 0,07883307 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01107464 0,07860052 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01107464 0,07836934 ! histidine catabolic process GO:0006548 6 5 0,000 0,01107464 0,07813952 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01107464 0,07791104 ! valine metabolic process GO:0006573 10 5 0,000 0,01107464 0,0776839 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01107464 0,07745807 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01107464 0,07723356 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01107464 0,07701034 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01107464 0,07678841 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01107464 0,07656775 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01107464 0,07634836 ! polyol catabolic process GO:0046174 7 5 0,000 0,01107464 0,07613022 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01107464 0,07591332 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01107464 0,07569766 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01107464 0,07548322 ! muscle cell migration GO:0014812 8 5 0,000 0,01107464 0,07526999 ! mitochondrial fission GO:0000266 8 5 0,000 0,01107464 0,07505796 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01107464 0,07484713 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01107464 0,07463747 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01107464 0,07442899 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01107464 0,07422166 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01107464 0,07401549 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01107464 0,07381046 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01107464 0,07360657 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01107464 0,07340379 ! response to food GO:0032094 6 5 0,000 0,01107464 0,07320213 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01107464 0,07300158 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01107464 0,07280212 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01107464 0,07260375 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01107464 0,07240646 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01107464 0,07221023 ! forebrain neuron development GO:0021884 13 5 0,000 0,01107464 0,07201507 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01107464 0,07182096 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01107464 0,07162789 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01107464 0,07143586 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01107464 0,07124486 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01107464 0,07105487 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01107464 0,0708659 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01107464 0,07067792 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01107464 0,07049094 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01107464 0,07030495 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01107464 0,07011994 ! basic amino acid transport GO:0015802 11 5 0,000 0,01107464 0,0699359 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01107464 0,06975282 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01107464 0,0695707 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01107464 0,06938952 ! depyrimidination GO:0045008 10 5 0,000 0,01107464 0,06920929 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01107464 0,06902999 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01107464 0,06885162 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01107464 0,06867417 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01107464 0,06849763 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01107464 0,06832199 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01107464 0,06814725 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01107464 0,06797341 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01107464 0,06780045 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01107464 0,06762837 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01107464 0,06745716 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01107464 0,06728681 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01107464 0,06711732 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01107464 0,06694869 ! response to arsenic GO:0046685 10 5 0,000 0,01107464 0,06678089 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01107464 0,06661394 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01107464 0,06644782 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01107464 0,06628253 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01107464 0,06611806 ! response to cadmium ion GO:0046686 7 5 0,000 0,01107464 0,0659544 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01107464 0,06579155 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01107464 0,0656295 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01107464 0,06546825 ! decidualization GO:0046697 11 5 0,000 0,01107464 0,06530779 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01107464 0,06514811 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01107464 0,06498921 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01107464 0,06483109 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01107464 0,06467373 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01107464 0,06451713 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01107464 0,0643613 ! neural tube patterning GO:0021532 7 5 0,000 0,01107464 0,06420621 ! embryonic cleavage GO:0040016 6 5 0,000 0,01107464 0,06405187 ! peroxisome fission GO:0016559 5 5 0,000 0,01107464 0,06389827 ! histone demethylation GO:0016577 10 5 0,000 0,01107464 0,0637454 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01107464 0,06359326 ! mitotic recombination GO:0006312 9 5 0,000 0,01107464 0,06344185 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01107464 0,06329116 ! metaphase plate congression GO:0051310 7 5 0,000 0,01107464 0,06314118 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01107464 0,06299191 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01107464 0,06284334 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01107464 0,06269547 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01107464 0,0625483 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01107464 0,06240182 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01107464 0,06225602 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01107464 0,0621109 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01107464 0,06196646 ! plasminogen activation GO:0031639 5 5 0,000 0,01107464 0,06182268 ! B cell homeostasis GO:0001782 13 5 0,000 0,01107464 0,06167958 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01107464 0,06153713 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01107464 0,06139534 ! metaphase GO:0051323 8 5 0,000 0,01107464 0,0612542 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01107464 0,06111371 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01107464 0,06097386 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01107464 0,06083465 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01107464 0,06069607 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01107464 0,06055813 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01107464 0,06042081 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01107464 0,06028411 ! response to redox state GO:0051775 5 5 0,000 0,01107464 0,06014803 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01107464 0,06001256 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01107464 0,0598777 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01107464 0,05974345 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01107464 0,05960979 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01107464 0,05947673 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01107464 0,05934427 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01107464 0,05921239 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01107464 0,0590811 ! striatum development GO:0021756 9 5 0,000 0,01107464 0,05895039 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01107464 0,05882026 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01107464 0,0586907 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01107464 0,05856171 ! glial cell migration GO:0008347 11 5 0,000 0,01107464 0,05843328 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01107464 0,05830542 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01107464 0,05817812 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01107464 0,05805137 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01107464 0,05792517 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01107464 0,05779952 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01107464 0,05767441 ! neuroprotection GO:0043526 6 5 0,000 0,01107464 0,05754984 ! neural plate development GO:0001840 8 5 0,000 0,01107464 0,05742581 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01107464 0,05730232 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01107464 0,05717935 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01107464 0,05705691 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01107464 0,05693499 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01107464 0,0568136 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01107464 0,05669272 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01107464 0,05657235 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01107464 0,05645249 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01107464 0,05633314 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01107464 0,0562143 ! spindle assembly GO:0051225 6 5 0,000 0,01107464 0,05609595 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01107464 0,0559781 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01107464 0,05586075 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01107464 0,05574388 ! drug metabolic process GO:0017144 6 5 0,000 0,01107464 0,05562751 ! stem cell division GO:0017145 11 5 0,000 0,01107464 0,05551162 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01107464 0,05539621 ! organ regeneration GO:0031100 7 5 0,000 0,01107464 0,05528128 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01107464 0,05516683 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01107464 0,05505284 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01107464 0,05493933 ! regulation of caspase activity GO:0043281 122 72 1,000 0,0112728 0,05580732 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,0112728 0,05569273 ! learning or memory GO:0007611 147 73 1,000 0,01157385 0,05706288 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01187842 0,05844475 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01187842 0,05832548 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,0121865 0,05971632 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01327502 0,0649181 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01327502 0,06478642 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01327502 0,06465527 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01327502 0,06452465 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01327502 0,06439456 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01327502 0,064265 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01327502 0,06413595 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01327502 0,06400742 ! sleep GO:0030431 13 6 0,000 0,01327502 0,06387941 ! response to oxygen radical GO:0000305 11 6 0,000 0,01327502 0,0637519 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01327502 0,06362491 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01327502 0,06349842 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01327502 0,06337243 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01327502 0,06324694 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01327502 0,06312194 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01327502 0,06299744 ! forebrain regionalization GO:0021871 8 6 0,000 0,01327502 0,06287343 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01327502 0,06274991 ! male meiosis GO:0007140 7 6 0,000 0,01327502 0,06262687 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01327502 0,06250431 ! response to zinc ion GO:0010043 9 6 0,000 0,01327502 0,06238223 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01327502 0,06226063 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01327502 0,0621395 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01327502 0,06201884 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01327502 0,06189865 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01327502 0,06177892 ! malate metabolic process GO:0006108 11 6 0,000 0,01327502 0,06165966 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01327502 0,06154085 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01327502 0,06142251 ! protein refolding GO:0042026 15 6 0,000 0,01327502 0,06130461 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01327502 0,06118717 ! opsonization GO:0008228 8 6 0,000 0,01327502 0,06107018 ! mating behavior GO:0007617 7 6 0,000 0,01327502 0,06095363 ! neuron remodeling GO:0016322 15 6 0,000 0,01327502 0,06083753 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01327502 0,06072187 ! equilibrioception GO:0050957 14 6 0,000 0,01327502 0,06060665 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01327502 0,06049186 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01327502 0,06037751 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01327502 0,06026359 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01327502 0,0601501 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01327502 0,06003704 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01327502 0,0599244 ! toxin metabolic process GO:0009404 11 6 0,000 0,01327502 0,05981218 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01327502 0,05970038 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01327502 0,059589 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01327502 0,05947803 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01327502 0,05936748 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01327502 0,05925733 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01327502 0,0591476 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01327502 0,05903827 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01327502 0,05892934 ! thymic T cell selection GO:0045061 12 6 0,000 0,01327502 0,05882082 ! protein lipoylation GO:0009249 10 6 0,000 0,01327502 0,05871269 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01327502 0,05860496 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01327502 0,05849763 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01327502 0,05839068 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01327502 0,05828413 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01327502 0,05817797 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01327502 0,05807219 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01327502 0,05796679 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01327502 0,05786178 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01327502 0,05775715 ! hyperosmotic response GO:0006972 9 6 0,000 0,01327502 0,05765289 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01327502 0,05754902 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01327502 0,05744551 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01327502 0,05734238 ! urea metabolic process GO:0019627 7 6 0,000 0,01327502 0,05723961 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01327502 0,05713722 ! neutrophil activation GO:0042119 8 6 0,000 0,01327502 0,05703518 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01327502 0,05693352 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01327502 0,05683221 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01327502 0,05673127 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01327502 0,05663068 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01327502 0,05653045 ! neuron apoptosis GO:0051402 9 6 0,000 0,01327502 0,05643057 ! nucleoside salvage GO:0043174 9 6 0,000 0,01327502 0,05633105 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01327502 0,05623187 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01327502 0,05613305 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01327502 0,05603457 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01327502 0,05593643 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01327502 0,05583864 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01327502 0,05574119 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01327502 0,05564408 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01327502 0,05554731 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01327502 0,05545087 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01327502 0,05535477 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01327502 0,055259 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01327502 0,05516356 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01327502 0,05506845 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01327502 0,05497367 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01327502 0,05487922 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01327502 0,05478508 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01327502 0,05469127 ! neural nucleus development GO:0048857 14 6 0,000 0,01327502 0,05459778 ! response to UV-C GO:0010225 11 6 0,000 0,01327502 0,05450461 ! astrocyte development GO:0014002 15 6 0,000 0,01327502 0,05441176 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01327502 0,05431922 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01327502 0,054227 ! interaction with symbiont GO:0051702 13 6 0,000 0,01327502 0,05413509 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01327502 0,05404349 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01327502 0,0539522 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01327502 0,05386122 ! response to copper ion GO:0046688 10 6 0,000 0,01327502 0,05377054 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01327502 0,05368017 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01327502 0,05359011 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01327502 0,05350034 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01327502 0,05341088 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01327502 0,05332171 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01327502 0,05323284 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01327502 0,05314427 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01327502 0,05305599 ! hair follicle maturation GO:0048820 7 6 0,000 0,01327502 0,052968 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01327502 0,0528803 ! Schwann cell development GO:0014044 15 6 0,000 0,01327502 0,0527929 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01327502 0,05270578 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01327502 0,05261895 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01327502 0,05253241 ! subpallium development GO:0021544 10 6 0,000 0,01327502 0,05244615 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01327502 0,05236017 ! histone ubiquitination GO:0016574 8 6 0,000 0,01327502 0,05227447 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01327502 0,05218906 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01327502 0,05210392 ! G2 phase GO:0051319 16 6 0,000 0,01327502 0,05201906 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01327502 0,05193448 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01327502 0,05185017 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01327502 0,05176613 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01327502 0,05168237 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01327502 0,05159887 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01327502 0,05151565 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01327502 0,05143269 ! receptor internalization GO:0031623 10 6 0,000 0,01327502 0,05135001 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01327502 0,05126758 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01327502 0,05118542 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01327502 0,05110353 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01327502 0,05102189 ! protein deubiquitination GO:0016579 14 6 0,000 0,01327502 0,05094052 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01327502 0,0508594 ! protein destabilization GO:0031648 9 6 0,000 0,01327502 0,05077854 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01327502 0,05069794 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01327502 0,0506176 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01327502 0,05053751 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01327502 0,05045767 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01327502 0,05037808 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01327502 0,05029875 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01327502 0,05021966 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01327502 0,05014082 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01327502 0,05006223 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01327502 0,04998389 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01327502 0,04990579 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01327502 0,04982793 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01327502 0,04975032 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01327502 0,04967294 ! catecholamine transport GO:0051937 9 6 0,000 0,01327502 0,04959581 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01327502 0,04951892 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01327502 0,04944227 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01327502 0,04936585 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01327502 0,04928967 ! maternal placenta development GO:0001893 12 6 0,000 0,01327502 0,04921372 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01327502 0,04913801 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01327502 0,04906252 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01327502 0,04898728 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01327502 0,04891226 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01327502 0,04883747 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01327502 0,04876291 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,01345351 0,04934321 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01345351 0,0492681 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01410761 0,05158497 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,01410761 0,0515067 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01443975 0,05263947 ! negative regulation of growth GO:0045926 155 84 1,000 0,01511414 0,05501456 ! tRNA transcription GO:0009304 14 7 0,000 0,01547058 0,05622693 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01547058 0,05614212 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01547058 0,05605757 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01547058 0,05597327 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01547058 0,05588923 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01547058 0,05580544 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01547058 0,0557219 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01547058 0,0556386 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01547058 0,05555556 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01547058 0,05547277 ! prostate gland development GO:0030850 13 7 0,000 0,01547058 0,05539022 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01547058 0,05530791 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01547058 0,05522585 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01547058 0,05514404 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01547058 0,05506246 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01547058 0,05498113 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01547058 0,05490004 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01547058 0,05481918 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01547058 0,05473857 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01547058 0,05465819 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01547058 0,05457804 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01547058 0,05449813 ! glycolipid transport GO:0046836 10 7 0,000 0,01547058 0,05441846 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01547058 0,05433902 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01547058 0,0542598 ! neuron adhesion GO:0007158 12 7 0,000 0,01547058 0,05418082 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01547058 0,05410207 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01547058 0,05402355 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01547058 0,05394526 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01547058 0,05386719 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01547058 0,05378934 ! mRNA stabilization GO:0048255 18 7 0,000 0,01547058 0,05371173 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01547058 0,05363433 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01547058 0,05355716 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01547058 0,05348021 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01547058 0,05340348 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01547058 0,05332697 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01547058 0,05325068 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01547058 0,05317461 ! lipoprotein transport GO:0042953 14 7 0,000 0,01547058 0,05309875 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01547058 0,05302311 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01547058 0,05294769 ! rhythmic behavior GO:0007622 15 7 0,000 0,01547058 0,05287248 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01547058 0,05279748 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01547058 0,0527227 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01547058 0,05264813 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01547058 0,05257377 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01547058 0,05249961 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01547058 0,05242567 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01547058 0,05235194 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01547058 0,05227841 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01547058 0,05220509 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01547058 0,05213197 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01547058 0,05205906 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01547058 0,05198635 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01547058 0,05191384 ! spinal cord patterning GO:0021511 13 7 0,000 0,01547058 0,05184154 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01547058 0,05176944 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01547058 0,05169754 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01547058 0,05162583 ! adrenal gland development GO:0030325 17 7 0,000 0,01547058 0,05155433 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01547058 0,05148302 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01547058 0,05141191 ! ovulation GO:0030728 9 7 0,000 0,01547058 0,051341 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01547058 0,05127028 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01547058 0,05119976 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01547058 0,05112943 ! microtubule nucleation GO:0007020 20 7 0,000 0,01547058 0,0510593 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01547058 0,05098935 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01547058 0,0509196 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01547058 0,05085004 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01547058 0,05078066 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01547058 0,05071148 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01547058 0,05064248 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01547058 0,05057368 ! galactose metabolic process GO:0006012 13 7 0,000 0,01547058 0,05050506 ! response to dietary excess GO:0002021 8 7 0,000 0,01547058 0,05043662 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01547058 0,05036837 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01547058 0,05030031 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01547058 0,05023242 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01547058 0,05016473 ! organ growth GO:0035265 15 7 0,000 0,01547058 0,05009721 ! purine salvage GO:0043101 10 7 0,000 0,01547058 0,05002987 ! nucleoside transport GO:0015858 8 7 0,000 0,01547058 0,04996272 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01547058 0,04989575 ! parturition GO:0007567 14 7 0,000 0,01547058 0,04982895 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01547058 0,04976233 ! rRNA modification GO:0000154 14 7 0,000 0,01547058 0,0496959 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01547058 0,04962963 ! spindle checkpoint GO:0031577 15 7 0,000 0,01547058 0,04956355 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01547058 0,04949764 ! macrophage differentiation GO:0030225 11 7 0,000 0,01547058 0,04943191 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01547058 0,04936635 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01547058 0,04930096 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01547058 0,04923575 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01547058 0,04917071 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01547058 0,04910584 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01547058 0,04904114 ! fibrinolysis GO:0042730 10 7 0,000 0,01547058 0,04897661 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01547058 0,04891226 ! eating behavior GO:0042755 7 7 0,000 0,01547058 0,04884807 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01547058 0,04878404 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01547058 0,04872019 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01547058 0,0486565 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01547058 0,04859298 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01547058 0,04852963 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01547058 0,04846644 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01547058 0,04840342 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01547058 0,04834055 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01547058 0,04827785 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01547058 0,04821532 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01547058 0,04815294 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01547058 0,04809073 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01547058 0,04802868 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01547058 0,04796679 ! regulation of meiosis GO:0040020 12 7 0,000 0,01547058 0,04790505 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01547058 0,04784348 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01547058 0,04778206 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01547058 0,0477208 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01547058 0,0476597 ! transcription termination GO:0006353 13 7 0,000 0,01547058 0,04759875 ! response to tumor cell GO:0002347 13 7 0,000 0,01547058 0,04753796 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01547058 0,04747733 ! anaphase GO:0051322 17 7 0,000 0,01547058 0,04741685 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01547058 0,04735652 ! axonal fasciculation GO:0007413 18 7 0,000 0,01547058 0,04729635 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01547058 0,04723633 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01547058 0,04717646 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01547058 0,04711674 ! diuresis GO:0030146 12 7 0,000 0,01547058 0,04705718 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01547058 0,04699776 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01547058 0,04693849 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01547058 0,04687938 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01547058 0,04682041 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01547058 0,04676159 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01547058 0,04670292 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01547058 0,04664439 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01547058 0,04658602 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01547058 0,04652778 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01547058 0,0464697 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01547058 0,04641175 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01547058 0,04635396 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01547058 0,0462963 ! lymph node development GO:0048535 10 7 0,000 0,01547058 0,04623879 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01547058 0,04618142 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01547058 0,0461242 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01547058 0,04606711 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01547058 0,04601017 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01547058 0,04595337 ! adult feeding behavior GO:0008343 9 7 0,000 0,01547058 0,0458967 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01547058 0,04584018 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01547058 0,0457838 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01547058 0,04572755 ! muscle adaptation GO:0043500 14 7 0,000 0,01547058 0,04567144 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01547058 0,04561547 ! retina homeostasis GO:0001895 12 7 0,000 0,01547058 0,04555964 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01547058 0,04550394 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01547058 0,04544838 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01547058 0,04539296 ! protein prenylation GO:0018342 18 7 0,000 0,01547058 0,04533767 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01547058 0,04528251 ! regulation of protein transport GO:0051223 154 87 1,000 0,01615074 0,04721589 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,01650288 0,04818679 ! ossification GO:0001503 188 90 1,000 0,01721697 0,05021093 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,01721697 0,05015015 ! bone development GO:0060348 189 91 1,000 0,01757889 0,05114244 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01766133 0,05132025 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01766133 0,05125835 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01766133 0,05119659 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01766133 0,05113498 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01766133 0,05107352 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01766133 0,05101221 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01766133 0,05095104 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01766133 0,05089002 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01766133 0,05082915 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01766133 0,05076842 ! meiotic prophase I GO:0007128 13 8 0,000 0,01766133 0,05070784 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01766133 0,0506474 ! oligopeptide transport GO:0006857 15 8 0,000 0,01766133 0,05058711 ! UTP metabolic process GO:0046051 8 8 0,000 0,01766133 0,05052696 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01766133 0,05046695 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01766133 0,05040708 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01766133 0,05034736 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01766133 0,05028777 ! succinate metabolic process GO:0006105 14 8 0,000 0,01766133 0,05022833 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01766133 0,05016903 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01766133 0,05010987 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01766133 0,05005085 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01766133 0,04999196 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01766133 0,04993322 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01766133 0,04987461 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01766133 0,04981614 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01766133 0,04975781 ! reflex GO:0060004 16 8 0,000 0,01766133 0,04969961 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01766133 0,04964155 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01766133 0,04958363 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01766133 0,04952584 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01766133 0,04946818 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01766133 0,04941066 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01766133 0,04935327 ! pigment granule organization GO:0048753 16 8 0,000 0,01766133 0,04929602 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01766133 0,0492389 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01766133 0,04918191 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01766133 0,04912505 ! histidine metabolic process GO:0006547 16 8 0,000 0,01766133 0,04906833 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01766133 0,04901173 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01766133 0,04895526 ! glycine catabolic process GO:0006546 13 8 0,000 0,01766133 0,04889893 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01766133 0,04884272 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01766133 0,04878665 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01766133 0,0487307 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01766133 0,04867488 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01766133 0,04861919 ! melanin metabolic process GO:0006582 15 8 0,000 0,01766133 0,04856362 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01766133 0,04850818 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01766133 0,04845287 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01766133 0,04839769 ! macrophage activation GO:0042116 12 8 0,000 0,01766133 0,04834263 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01766133 0,04828769 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01766133 0,04823288 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01766133 0,0481782 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01766133 0,04812364 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01766133 0,0480692 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01766133 0,04801488 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01766133 0,04796069 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01766133 0,04790662 ! osteoblast development GO:0002076 16 8 0,000 0,01766133 0,04785267 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01766133 0,04779884 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01766133 0,04774513 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01766133 0,04769155 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01766133 0,04763808 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01766133 0,04758474 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01766133 0,04753151 ! response to UV-B GO:0010224 16 8 0,000 0,01766133 0,0474784 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01766133 0,04742541 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01766133 0,04737254 ! intermediate filament organization GO:0045109 12 8 0,000 0,01766133 0,04731979 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01766133 0,04726715 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01766133 0,04721463 ! cellular extravasation GO:0045123 12 8 0,000 0,01766133 0,04716223 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01766133 0,04710994 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01766133 0,04705777 ! response to antibiotic GO:0046677 11 8 0,000 0,01766133 0,04700572 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01766133 0,04695378 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01766133 0,04690195 ! DNA topological change GO:0006265 12 8 0,000 0,01766133 0,04685024 ! response to tropane GO:0014073 15 8 0,000 0,01766133 0,04679865 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01766133 0,04674716 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01766133 0,04669579 ! melanosome transport GO:0032402 13 8 0,000 0,01766133 0,04664453 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,01766133 0,04659339 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01766133 0,04654235 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01766133 0,04649143 ! mast cell activation GO:0045576 14 8 0,000 0,01766133 0,04644062 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01766133 0,04638992 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01766133 0,04633933 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01766133 0,04628886 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01766133 0,04623849 ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01766133 0,04618823 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01766133 0,04613808 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01766133 0,04608804 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01766133 0,0460381 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01766133 0,04598828 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01766133 0,04593856 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01766133 0,04588895 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01766133 0,04583945 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01766133 0,04579005 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01766133 0,04574076 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01766133 0,04569158 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01766133 0,0456425 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01766133 0,04559353 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01766133 0,04554466 ! hormone catabolic process GO:0042447 17 8 0,000 0,01766133 0,0454959 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01766133 0,04544724 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01766133 0,04539869 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01766133 0,04535023 ! ATP catabolic process GO:0006200 11 8 0,000 0,01766133 0,04530189 ! blastocyst growth GO:0001832 19 8 0,000 0,01766133 0,04525364 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01766133 0,0452055 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01766133 0,04515746 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01766133 0,04510952 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01766133 0,04506169 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01766133 0,04501395 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01766133 0,04496632 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01766133 0,04491878 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01766133 0,04487135 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01766133 0,04482402 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01766133 0,04477679 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01766133 0,04472965 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01766133 0,04468262 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01766133 0,04463568 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01766133 0,04458885 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01766133 0,04454211 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01766133 0,04449547 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,0183124 0,04608748 ! regulation of membrane potential GO:0042391 164 93 1,000 0,0183124 0,04603932 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,0183124 0,04599126 ! mRNA transport GO:0051028 169 96 1,000 0,01943661 0,0487638 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,01981767 0,04966804 ! regulation of protein localization GO:0032880 176 97 1,000 0,01981767 0,04961636 ! axon extension GO:0048675 15 9 0,000 0,01984728 0,04963883 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01984728 0,04958729 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01984728 0,04953585 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01984728 0,04948452 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01984728 0,04943329 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01984728 0,04938217 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01984728 0,04933116 ! phosphate transport GO:0006817 19 9 0,000 0,01984728 0,04928025 ! reproductive behavior GO:0019098 19 9 0,000 0,01984728 0,04922944 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01984728 0,04917874 ! CTP metabolic process GO:0046036 9 9 0,000 0,01984728 0,04912815 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01984728 0,04907766 ! GTP metabolic process GO:0046039 9 9 0,000 0,01984728 0,04902727 ! RNA methylation GO:0001510 15 9 0,000 0,01984728 0,04897698 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01984728 0,0489268 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01984728 0,04887672 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01984728 0,04882675 ! artery development GO:0060840 24 9 0,000 0,01984728 0,04877687 GO:0048844|artery morphogenesis, ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01984728 0,0487271 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01984728 0,04867743 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01984728 0,04862786 ! chemosensory behavior GO:0007635 20 9 0,000 0,01984728 0,04857839 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01984728 0,04852902 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01984728 0,04847976 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01984728 0,04843059 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01984728 0,04838152 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01984728 0,04833255 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01984728 0,04828368 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01984728 0,04823491 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01984728 0,04818624 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01984728 0,04813766 ! protein targeting to ER GO:0045047 22 9 0,000 0,01984728 0,04808918 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01984728 0,0480408 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01984728 0,04799252 ! T cell selection GO:0045058 23 9 0,000 0,01984728 0,04794434 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01984728 0,04789625 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01984728 0,04784826 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01984728 0,04780036 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01984728 0,04775256 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01984728 0,04770485 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01984728 0,04765724 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01984728 0,04760973 ! mannose metabolic process GO:0006013 13 9 0,000 0,01984728 0,04756231 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01984728 0,04751498 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01984728 0,04746775 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01984728 0,04742061 ! receptor clustering GO:0043113 18 9 0,000 0,01984728 0,04737357 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01984728 0,04732662 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01984728 0,04727976 ! ruffle organization GO:0031529 15 9 0,000 0,01984728 0,047233 ! retinol metabolic process GO:0042572 18 9 0,000 0,01984728 0,04718632 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01984728 0,04713974 ! behavioral fear response GO:0001662 22 9 0,000 0,01984728 0,04709325 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01984728 0,04704686 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01984728 0,04700055 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01984728 0,04695434 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01984728 0,04690821 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01984728 0,04686218 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01984728 0,04681623 ! segment specification GO:0007379 13 9 0,000 0,01984728 0,04677038 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01984728 0,04672462 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01984728 0,04667894 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01984728 0,04663336 ! response to amine stimulus GO:0014075 13 9 0,000 0,01984728 0,04658786 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01984728 0,04654246 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01984728 0,04649714 ! erythrocyte development GO:0048821 15 9 0,000 0,01984728 0,04645191 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01984728 0,04640676 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01984728 0,04636171 ! renal water homeostasis GO:0003091 14 9 0,000 0,01984728 0,04631674 ! postreplication repair GO:0006301 22 9 0,000 0,01984728 0,04627186 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01984728 0,04622707 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01984728 0,04618236 ! icosanoid secretion GO:0032309 15 9 0,000 0,01984728 0,04613774 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01984728 0,0460932 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01984728 0,04604876 ! regulation of cell division GO:0051302 15 9 0,000 0,01984728 0,04600439 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01984728 0,04596011 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01984728 0,04591592 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01984728 0,04587181 ! sterol catabolic process GO:0016127 11 9 0,000 0,01984728 0,04582779 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01984728 0,04578385 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01984728 0,04574 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01984728 0,04569623 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01984728 0,04565254 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01984728 0,04560894 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01984728 0,04556542 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01984728 0,04552198 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01984728 0,04547863 ! purine base metabolic process GO:0006144 21 9 0,000 0,01984728 0,04543536 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01984728 0,04539217 ! pigment granule transport GO:0051904 17 9 0,000 0,01984728 0,04534906 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01984728 0,04530603 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01984728 0,04526309 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01984728 0,04522023 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01984728 0,04517744 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01984728 0,04513474 ! mitochondrion localization GO:0051646 15 9 0,000 0,01984728 0,04509212 ! cell cycle arrest GO:0007050 213 100 1,000 0,02097961 0,04761975 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02202844 0,04995327 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02202844 0,04990623 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02202844 0,04985928 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02202844 0,04981242 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02202844 0,04976565 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02202844 0,04971897 ! synapsis GO:0007129 13 10 0,000 0,02202844 0,04967237 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02202844 0,04962586 ! N-glycan processing GO:0006491 20 10 0,000 0,02202844 0,04957944 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02202844 0,0495331 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02202844 0,04948685 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02202844 0,04944069 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02202844 0,04939461 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02202844 0,04934862 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02202844 0,04930272 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02202844 0,0492569 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02202844 0,04921116 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02202844 0,04916551 ! androgen metabolic process GO:0008209 17 10 0,000 0,02202844 0,04911994 ! phospholipid efflux GO:0033700 16 10 0,000 0,02202844 0,04907446 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02202844 0,04902907 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02202844 0,04898375 ! lung alveolus development GO:0048286 26 10 0,000 0,02202844 0,04893852 ! pathogenesis GO:0009405 13 10 0,000 0,02202844 0,04889338 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02202844 0,04884831 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02202844 0,04880333 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02202844 0,04875844 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02202844 0,04871362 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02202844 0,04866889 ! endoderm development GO:0007492 16 10 0,000 0,02202844 0,04862424 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02202844 0,04857967 ! arginine catabolic process GO:0006527 13 10 0,000 0,02202844 0,04853518 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02202844 0,04849078 ! proline metabolic process GO:0006560 13 10 0,000 0,02202844 0,04844645 ! L-serine metabolic process GO:0006563 18 10 0,000 0,02202844 0,04840221 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02202844 0,04835805 ! V(D)J recombination GO:0033151 28 10 0,000 0,02202844 0,04831396 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02202844 0,04826996 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02202844 0,04822604 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02202844 0,0481822 ! B cell proliferation GO:0042100 18 10 0,000 0,02202844 0,04813844 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02202844 0,04809475 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02202844 0,04805115 ! multicellular organism growth GO:0035264 18 10 0,000 0,02202844 0,04800763 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02202844 0,04796418 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02202844 0,04792081 ! epithelial cell development GO:0002064 20 10 0,000 0,02202844 0,04787752 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02202844 0,04783431 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02202844 0,04779118 ! macroautophagy GO:0016236 17 10 0,000 0,02202844 0,04774813 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02202844 0,04770515 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02202844 0,04766225 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02202844 0,04761942 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02202844 0,04757668 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02202844 0,04753401 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02202844 0,04749142 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02202844 0,0474489 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02202844 0,04740646 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02202844 0,04736409 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02202844 0,0473218 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02202844 0,04727959 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02202844 0,04723745 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02202844 0,04719539 ! response to dsRNA GO:0043331 20 10 0,000 0,02202844 0,0471534 ! DNA ligation GO:0006266 19 10 0,000 0,02202844 0,04711148 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02202844 0,04706964 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02202844 0,04702788 ! melanosome localization GO:0032400 16 10 0,000 0,02202844 0,04698619 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02202844 0,04694457 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02202844 0,04690303 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02202844 0,04686156 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02202844 0,04682016 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02202844 0,04677883 ! mRNA cleavage GO:0006379 17 10 0,000 0,02202844 0,04673758 ! protein sumoylation GO:0016925 15 10 0,000 0,02202844 0,0466964 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02202844 0,0466553 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02202844 0,04661427 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02202844 0,0465733 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02202844 0,04653241 ! salivary gland development GO:0007431 27 10 0,000 0,02202844 0,0464916 ! prophase GO:0051324 15 10 0,000 0,02202844 0,04645085 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02202844 0,04641017 ! apical protein localization GO:0045176 15 10 0,000 0,02202844 0,04636957 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02202844 0,04632904 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02202844 0,04628858 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02202844 0,04624818 ! midbrain development GO:0030901 13 10 0,000 0,02202844 0,04620786 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02202844 0,04616761 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02202844 0,04612743 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02202844 0,04608732 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02202844 0,04604728 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02202844 0,04600731 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02202844 0,04596741 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02202844 0,04592757 ! detection of calcium ion GO:0005513 23 10 0,000 0,02202844 0,04588781 ! oocyte development GO:0048599 17 10 0,000 0,02202844 0,04584811 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02202844 0,04580849 ! blastocyst formation GO:0001825 17 10 0,000 0,02202844 0,04576893 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02202844 0,04572944 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02202844 0,04569002 ! activation of innate immune response GO:0002218 12 10 0,000 0,02202844 0,04565066 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02202844 0,04561138 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02202844 0,04557216 ! response to nicotine GO:0035094 20 10 0,000 0,02202844 0,04553301 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02202844 0,04549392 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02202844 0,04545491 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02420481 0,04990298 ! respiratory burst GO:0045730 17 11 0,000 0,02420481 0,04986025 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02420481 0,0498176 ! neuron fate specification GO:0048665 17 11 0,000 0,02420481 0,04977502 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02420481 0,04973252 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02420481 0,04969008 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02420481 0,04964772 ! thyroid gland development GO:0030878 26 11 0,000 0,02420481 0,04960543 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02420481 0,04956321 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02420481 0,04952107 ! response to pain GO:0048265 24 11 0,000 0,02420481 0,04947899 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02420481 0,04943699 ! T cell proliferation GO:0042098 26 11 0,000 0,02420481 0,04939506 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02420481 0,0493532 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02420481 0,04931141 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,02420481 0,04926969 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02420481 0,04922804 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02420481 0,04918647 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02420481 0,04914496 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02420481 0,04910352 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02420481 0,04906215 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02420481 0,04902085 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02420481 0,04897963 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02420481 0,04893847 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02420481 0,04889738 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02420481 0,04885636 ! lipid digestion GO:0044241 18 11 0,000 0,02420481 0,0488154 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02420481 0,04877452 ! UV protection GO:0009650 19 11 0,000 0,02420481 0,0487337 ! adult heart development GO:0007512 14 11 0,000 0,02420481 0,04869296 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02420481 0,04865228 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02420481 0,04861167 ! temperature homeostasis GO:0001659 17 11 0,000 0,02420481 0,04857112 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02420481 0,04853065 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02420481 0,04849024 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02420481 0,0484499 ! regulation of organ growth GO:0046620 13 11 0,000 0,02420481 0,04840962 ! pigment granule localization GO:0051875 20 11 0,000 0,02420481 0,04836941 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02420481 0,04832927 ! vasoconstriction GO:0042310 18 11 0,000 0,02420481 0,0482892 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02420481 0,04824919 ! embryonic axis specification GO:0000578 18 11 0,000 0,02420481 0,04820925 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02420481 0,04816938 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02420481 0,04812957 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02420481 0,04808982 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02420481 0,04805014 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02420481 0,04801053 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02420481 0,04797098 ! zymogen activation GO:0031638 15 11 0,000 0,02420481 0,0479315 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02420481 0,04789209 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02420481 0,04785273 ! nucleosome positioning GO:0016584 15 11 0,000 0,02420481 0,04781344 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02420481 0,04777422 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02420481 0,04773506 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02420481 0,04769597 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02420481 0,04765694 ! acid secretion GO:0046717 18 11 0,000 0,02420481 0,04761797 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02420481 0,04757907 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02420481 0,04754022 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02420481 0,04750145 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02420481 0,04746273 ! oocyte differentiation GO:0009994 18 11 0,000 0,02420481 0,04742408 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02420481 0,0473855 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,02420481 0,04734697 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02420481 0,04730851 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02420481 0,04727011 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02420481 0,04723177 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02420481 0,0471935 ! embryonic gut development GO:0048566 15 11 0,000 0,02420481 0,04715528 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02420481 0,04711713 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02420481 0,04707904 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02420481 0,04704101 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02420481 0,04700305 ! defense response to fungus GO:0050832 13 11 0,000 0,02420481 0,04696514 ! lysogeny GO:0030069 21 11 0,000 0,02420481 0,0469273 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02420481 0,04688951 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02420481 0,04685179 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02420481 0,04681413 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02420481 0,04677653 ! nucleus localization GO:0051647 19 11 0,000 0,02420481 0,04673899 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02420481 0,0467015 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02637641 0,05085068 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02637641 0,05080997 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02637641 0,05076932 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02637641 0,05072874 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02637641 0,05068822 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02637641 0,05064777 ! cartilage condensation GO:0001502 20 12 0,000 0,02637641 0,05060738 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02637641 0,05056705 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02637641 0,05052679 ! protein complex disassembly GO:0043241 27 12 0,000 0,02637641 0,0504866 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02637641 0,05044646 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02637641 0,0504064 ! hippocampus development GO:0021766 26 12 0,000 0,02637641 0,05036639 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02637641 0,05032645 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02637641 0,05028657 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02637641 0,05024676 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02637641 0,050207 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02637641 0,05016731 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02637641 0,05012769 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02637641 0,05008812 ! drug transport GO:0015893 16 12 0,000 0,02637641 0,05004862 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02637641 0,05000918 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02637641 0,0499698 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02637641 0,04993049 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02637641 0,04989124 ! focal adhesion formation GO:0048041 35 12 0,000 0,02637641 0,04985204 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02637641 0,04981291 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02637641 0,04977384 ! forebrain cell migration GO:0021885 21 12 0,000 0,02637641 0,04973484 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02637641 0,04969589 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02637641 0,049657 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02637641 0,04961818 ! entry into host cell GO:0030260 32 12 0,000 0,02637641 0,04957942 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02637641 0,04954071 ! monoamine transport GO:0015844 18 12 0,000 0,02637641 0,04950207 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02637641 0,04946349 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02637641 0,04942496 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02637641 0,0493865 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02637641 0,0493481 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02637641 0,04930975 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02637641 0,04927147 ! protein homotetramerization GO:0051289 21 12 0,000 0,02637641 0,04923324 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02637641 0,04919508 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02637641 0,04915697 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02637641 0,04911893 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02637641 0,04908094 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02637641 0,04904301 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02637641 0,04900514 ! cranial nerve development GO:0021545 20 12 0,000 0,02637641 0,04896732 ! fucose catabolic process GO:0019317 22 12 0,000 0,02637641 0,04892957 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02637641 0,04889187 ! histone methylation GO:0016571 26 12 0,000 0,02637641 0,04885424 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02637641 0,04881666 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02637641 0,04877913 ! T cell homeostasis GO:0043029 25 12 0,000 0,02637641 0,04874167 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02637641 0,04870426 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02637641 0,04866691 ! spleen development GO:0048536 22 12 0,000 0,02637641 0,04862962 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02637641 0,04859238 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02637641 0,0485552 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02637641 0,04851808 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02637641 0,04848102 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02637641 0,04844401 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02637641 0,04840706 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02637641 0,04837016 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02637641 0,04833332 ! response to cold GO:0009409 17 12 0,000 0,02637641 0,04829654 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02637641 0,04825981 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02637641 0,04822314 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02854326 0,05214508 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02854326 0,05210552 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02854326 0,05206602 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02854326 0,05202657 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02854326 0,05198719 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02854326 0,05194786 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02854326 0,0519086 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02854326 0,05186939 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02854326 0,05183024 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02854326 0,05179116 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02854326 0,05175213 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02854326 0,05171316 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02854326 0,05167425 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02854326 0,05163539 ! methionine metabolic process GO:0006555 27 13 0,000 0,02854326 0,0515966 ! plasma membrane organization GO:0007009 24 13 0,000 0,02854326 0,05155786 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02854326 0,05151919 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02854326 0,05148057 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02854326 0,051442 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02854326 0,0514035 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02854326 0,05136505 ! response to X-ray GO:0010165 25 13 0,000 0,02854326 0,05132666 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02854326 0,05128833 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02854326 0,05125006 ! exocrine system development GO:0035272 32 13 0,000 0,02854326 0,05121184 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02854326 0,05117368 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02854326 0,05113557 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02854326 0,05109753 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02854326 0,05105953 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02854326 0,0510216 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02854326 0,05098372 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02854326 0,0509459 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02854326 0,05090814 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02854326 0,05087043 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02854326 0,05083277 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02854326 0,05079517 ! ribosome assembly GO:0042255 17 13 0,000 0,02854326 0,05075763 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02854326 0,05072014 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02854326 0,05068271 ! chromatin silencing GO:0006342 26 13 0,000 0,02854326 0,05064533 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02854326 0,05060801 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02854326 0,05057075 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02854326 0,05053354 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02854326 0,05049638 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02854326 0,05045928 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02854326 0,05042223 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02854326 0,05038523 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02854326 0,05034829 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02854326 0,05031141 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02854326 0,05027458 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02854326 0,0502378 ! insulin secretion GO:0030073 23 13 0,000 0,02854326 0,05020108 ! actin filament polymerization GO:0030041 24 13 0,000 0,02854326 0,05016441 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02854326 0,05012779 ! acrosome reaction GO:0007340 18 13 0,000 0,02854326 0,05009123 ! rRNA transcription GO:0009303 25 14 0,000 0,03070535 0,05384626 ! lactation GO:0007595 26 14 0,000 0,03070535 0,05380704 ! reproductive cellular process GO:0048610 20 14 0,000 0,03070535 0,05376788 ! tRNA modification GO:0006400 20 14 0,000 0,03070535 0,05372878 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03070535 0,05368973 ! regulation of S phase GO:0033261 23 14 0,000 0,03070535 0,05365074 ! water transport GO:0006833 21 14 0,000 0,03070535 0,0536118 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03070535 0,05357293 ! non-recombinational repair GO:0000726 25 14 0,000 0,03070535 0,05353411 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03070535 0,05349534 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03070535 0,05345663 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03070535 0,05341798 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03070535 0,05337938 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03070535 0,05334084 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03070535 0,05330236 ! palate development GO:0060021 31 14 0,000 0,03070535 0,05326393 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03070535 0,05322555 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03070535 0,05318723 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03070535 0,05314897 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03070535 0,05311076 ! arginine metabolic process GO:0006525 17 14 0,000 0,03070535 0,05307261 ! regulation of heart rate GO:0002027 24 14 0,000 0,03070535 0,05303451 ! organic alcohol transport GO:0015850 29 14 0,000 0,03070535 0,05299646 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03070535 0,05295847 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03070535 0,05292053 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03070535 0,05288265 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03070535 0,05284483 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03070535 0,05280705 ! L-amino acid transport GO:0015807 30 14 0,000 0,03070535 0,05276933 ! bone mineralization GO:0030282 17 14 0,000 0,03070535 0,05273167 ! stem cell development GO:0048864 43 14 0,000 0,03070535 0,05269406 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03070535 0,0526565 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03070535 0,05261899 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03070535 0,05258154 ! cerebellum development GO:0021549 21 14 0,000 0,03070535 0,05254414 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03070535 0,0525068 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03070535 0,05246951 ! response to gamma radiation GO:0010332 28 14 0,000 0,03070535 0,05243227 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03070535 0,05239508 ! cofactor transport GO:0051181 26 14 0,000 0,03070535 0,05235795 ! NADP metabolic process GO:0006739 24 14 0,000 0,03070535 0,05232087 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03070535 0,05228384 ! intestinal absorption GO:0050892 25 14 0,000 0,03070535 0,05224686 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03070535 0,05220994 ! oxygen transport GO:0015671 21 14 0,000 0,03070535 0,05217307 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03070535 0,05213625 ! male genitalia development GO:0030539 24 14 0,000 0,03070535 0,05209948 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03070535 0,05206277 ! regulation of axon extension GO:0030516 37 14 0,000 0,03070535 0,0520261 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,03070535 0,05198949 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03070535 0,05195293 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0328627 0,05556406 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0328627 0,05552504 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0328627 0,05548607 ! superoxide anion generation GO:0042554 20 15 0,000 0,0328627 0,05544716 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0328627 0,05540831 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0328627 0,05536951 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0328627 0,05533076 ! copper ion transport GO:0006825 20 15 0,000 0,0328627 0,05529207 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0328627 0,05525343 ! sulfate transport GO:0008272 23 15 0,000 0,0328627 0,05521484 ! response to cAMP GO:0051591 22 15 0,000 0,0328627 0,05517631 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0328627 0,05513783 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0328627 0,05509941 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0328627 0,05506104 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0328627 0,05502272 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0328627 0,05498446 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0328627 0,05494625 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0328627 0,05490809 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0328627 0,05486999 ! pituitary gland development GO:0021983 29 15 0,000 0,0328627 0,05483194 ! vesicle coating GO:0006901 33 15 0,000 0,0328627 0,05479394 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0328627 0,05475599 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0328627 0,0547181 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0328627 0,05468026 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0328627 0,05464247 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0328627 0,05460473 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0328627 0,05456705 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0328627 0,05452942 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0328627 0,05449184 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0328627 0,05445431 ! histone deacetylation GO:0016575 20 15 0,000 0,0328627 0,05441683 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0328627 0,0543794 ! tissue regeneration GO:0042246 26 15 0,000 0,0328627 0,05434203 ! water homeostasis GO:0030104 27 15 0,000 0,0328627 0,05430471 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0328627 0,05426744 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0328627 0,05423021 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0328627 0,05419305 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0328627 0,05415593 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0328627 0,05411886 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0328627 0,05408184 ! cell killing GO:0001906 29 15 0,000 0,0328627 0,05404488 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0328627 0,05400796 ! detection of bacterium GO:0016045 18 15 0,000 0,0328627 0,05397109 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0328627 0,05393428 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0328627 0,05389751 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0328627 0,0538608 ! peptide hormone processing GO:0016486 23 15 0,000 0,0328627 0,05382413 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03501532 0,05731079 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03501532 0,05727183 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03501532 0,05723292 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03501532 0,05719407 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03501532 0,05715526 ! bone remodeling GO:0046849 27 16 0,000 0,03501532 0,05711651 ! filopodium assembly GO:0046847 32 16 0,000 0,03501532 0,05707782 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03501532 0,05703917 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03501532 0,05700058 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03501532 0,05696204 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03501532 0,05692355 ! startle response GO:0001964 28 16 0,000 0,03501532 0,05688512 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03501532 0,05684673 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03501532 0,0568084 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03501532 0,05677012 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03501532 0,05673189 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03501532 0,05669371 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03501532 0,05665559 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03501532 0,05661751 ! response to osmotic stress GO:0006970 25 16 0,000 0,03501532 0,05657949 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03501532 0,05654152 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03501532 0,05650359 ! fructose metabolic process GO:0006000 25 16 0,000 0,03501532 0,05646572 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03501532 0,0564279 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03501532 0,05639013 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03501532 0,05635241 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03501532 0,05631475 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03501532 0,05627713 ! axon cargo transport GO:0008088 43 16 0,000 0,03501532 0,05623956 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03501532 0,05620204 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03501532 0,05616457 ! DNA replication initiation GO:0006270 27 16 0,000 0,03501532 0,05612715 ! neuron recognition GO:0008038 35 16 0,000 0,03501532 0,05608979 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03501532 0,05605247 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03501532 0,0560152 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03501532 0,05597798 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03501532 0,05594081 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03501532 0,05590369 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03501532 0,05586662 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03501532 0,0558296 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03501532 0,05579262 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03501532 0,0557557 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03501532 0,05571882 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03501532 0,055682 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03501532 0,05564522 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03501532 0,05560849 ! defense response to virus GO:0051607 37 16 0,000 0,03501532 0,05557181 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03716322 0,0589418 ! metencephalon development GO:0022037 30 17 0,000 0,03716322 0,05890297 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03716322 0,05886419 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03716322 0,05882547 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03716322 0,05878679 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03716322 0,05874817 ! signal complex assembly GO:0007172 41 17 0,000 0,03716322 0,05870959 ! endothelial cell migration GO:0043542 28 17 0,000 0,03716322 0,05867107 ! inositol metabolic process GO:0006020 28 17 0,000 0,03716322 0,0586326 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03716322 0,05859417 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03716322 0,0585558 ! glial cell development GO:0021782 27 17 0,000 0,03716322 0,05851748 ! limbic system development GO:0021761 36 17 0,000 0,03716322 0,05847921 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03716322 0,05844099 ! adult walking behavior GO:0007628 33 17 0,000 0,03716322 0,05840281 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03716322 0,05836469 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03716322 0,05832662 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03716322 0,0582886 ! myoblast differentiation GO:0045445 45 17 0,000 0,03716322 0,05825063 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03716322 0,0582127 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03716322 0,05817483 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03716322 0,058137 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03716322 0,05809923 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03716322 0,0580615 ! glycine metabolic process GO:0006544 28 17 0,000 0,03716322 0,05802382 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03716322 0,05798619 ! NAD metabolic process GO:0019674 29 17 0,000 0,03716322 0,05794861 ! membrane budding GO:0006900 37 17 0,000 0,03716322 0,05791108 ! DNA integration GO:0015074 29 17 0,000 0,03716322 0,0578736 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03716322 0,05783616 ! regulation of protein binding GO:0043393 33 17 0,000 0,03716322 0,05779878 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03716322 0,05776144 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03716322 0,05772415 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03716322 0,05768691 ! genitalia development GO:0048806 30 17 0,000 0,03716322 0,05764972 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03716322 0,05761257 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03716322 0,05757547 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03716322 0,05753842 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03716322 0,05750142 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03716322 0,05746447 ! steroid catabolic process GO:0006706 31 17 0,000 0,03716322 0,05742756 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03716322 0,0573907 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03716322 0,05735389 ! gas transport GO:0015669 25 17 0,000 0,03716322 0,05731712 ! organic cation transport GO:0015695 31 17 0,000 0,03716322 0,0572804 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03716322 0,05724373 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03716322 0,05720711 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03716322 0,05717053 ! microspike assembly GO:0030035 36 17 0,000 0,03716322 0,057134 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03716322 0,05709752 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03716322 0,05706108 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03930641 0,06031328 ! neuron maturation GO:0042551 42 18 0,000 0,03930641 0,06027484 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03930641 0,06023645 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03930641 0,06019811 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,03930641 0,06015981 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03930641 0,06012157 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03930641 0,06008337 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03930641 0,06004522 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03930641 0,06000712 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03930641 0,05996907 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03930641 0,05993107 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03930641 0,05989311 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03930641 0,05985521 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03930641 0,05981735 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03930641 0,05977954 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03930641 0,05974177 ! response to retinoic acid GO:0032526 26 18 0,000 0,03930641 0,05970406 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03930641 0,05966639 ! response to fungus GO:0009620 21 18 0,000 0,03930641 0,05962877 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03930641 0,0595912 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03930641 0,05955367 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03930641 0,05951619 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03930641 0,05947876 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03930641 0,05944138 ! vitamin transport GO:0051180 27 18 0,000 0,03930641 0,05940404 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03930641 0,05936675 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03930641 0,0593295 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03930641 0,05929231 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03930641 0,05925516 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03930641 0,05921805 ! nerve development GO:0021675 28 18 0,000 0,03930641 0,05918099 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03930641 0,05914398 ! positive regulation of translation GO:0045727 30 19 0,000 0,0414449 0,06232278 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0414449 0,06228385 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0414449 0,06224497 ! skin development GO:0043588 36 19 0,000 0,0414449 0,06220614 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0414449 0,06216736 ! lipid phosphorylation GO:0046834 35 19 0,000 0,0414449 0,06212862 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0414449 0,06208994 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0414449 0,0620513 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0414449 0,06201271 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0414449 0,06197417 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0414449 0,06193568 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0414449 0,06189723 ! cerebral cortex development GO:0021987 36 19 0,000 0,0414449 0,06185883 ! pigmentation during development GO:0048066 41 19 0,000 0,0414449 0,06182048 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,0414449 0,06178218 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,0414449 0,06174393 ! heme metabolic process GO:0042168 36 19 0,000 0,0414449 0,06170572 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0414449 0,06166756 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0414449 0,06162944 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0414449 0,06159138 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0414449 0,06155336 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0414449 0,06151539 ! peptide cross-linking GO:0018149 37 19 0,000 0,0414449 0,06147746 ! protein export from nucleus GO:0006611 36 19 0,000 0,0414449 0,06143958 ! heart process GO:0003015 30 19 0,000 0,0414449 0,06140175 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0414449 0,06136396 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0414449 0,06132622 ! visual learning GO:0008542 36 19 0,000 0,0414449 0,06128853 ! cellular pigmentation GO:0033059 36 19 0,000 0,0414449 0,06125088 ! G1 phase GO:0051318 40 19 0,000 0,0414449 0,06121328 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0414449 0,06117573 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0414449 0,06113822 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0414449 0,06110076 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0414449 0,06106334 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0414449 0,06102597 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0414449 0,06098865 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0414449 0,06095137 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0414449 0,06091414 ! cilium assembly GO:0042384 37 19 0,000 0,0414449 0,06087695 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0414449 0,0608398 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04357871 0,06393315 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04357871 0,06389419 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04357871 0,06385528 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04357871 0,06381641 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04357871 0,0637776 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04357871 0,06373883 ! response to vitamin GO:0033273 31 20 0,000 0,04357871 0,0637001 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04357871 0,06366143 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04357871 0,0636228 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04357871 0,06358421 ! response to alkaloid GO:0043279 38 20 0,000 0,04357871 0,06354568 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04357871 0,06350719 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04357871 0,06346875 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,04357871 0,06343035 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04357871 0,063392 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04357871 0,0633537 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04357871 0,06331544 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04357871 0,06327723 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04357871 0,06323906 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04357871 0,06320095 ! body fluid secretion GO:0007589 31 20 0,000 0,04357871 0,06316287 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04357871 0,06312485 ! peptide secretion GO:0002790 35 20 0,000 0,04357871 0,06308686 ! stem cell differentiation GO:0048863 53 20 0,000 0,04357871 0,06304893 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04357871 0,06301104 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04357871 0,06297319 ! sensory perception of pain GO:0019233 30 20 0,000 0,04357871 0,0629354 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04357871 0,06289764 ! diencephalon development GO:0021536 34 20 0,000 0,04357871 0,06285993 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04357871 0,06282227 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04357871 0,06278465 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04357871 0,06274708 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04357871 0,06270955 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04357871 0,06267207 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04357871 0,06263463 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04357871 0,06259724 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04357871 0,06255989 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04357871 0,06252258 ! regulation of glucose import GO:0046324 29 20 0,000 0,04357871 0,06248532 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04357871 0,06244811 ! actin filament-based movement GO:0030048 43 20 0,000 0,04357871 0,06241093 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,04357871 0,06237381 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04357871 0,06233672 ! negative regulation of translation GO:0017148 29 20 0,000 0,04357871 0,06229968 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04357871 0,06226269 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04357871 0,06222574 ! regulation of cell killing GO:0031341 42 21 0,000 0,04570783 0,06522719 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04570783 0,06518852 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04570783 0,06514991 ! hormone secretion GO:0046879 38 21 0,000 0,04570783 0,06511133 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04570783 0,0650728 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04570783 0,06503432 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04570783 0,06499589 ! axis specification GO:0009798 38 21 0,000 0,04570783 0,0649575 ! ovarian follicle development GO:0001541 35 21 0,000 0,04570783 0,06491915 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04570783 0,06488085 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04570783 0,06484259 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04570783 0,06480438 ! cell aging GO:0007569 44 21 0,000 0,04570783 0,06476622 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04570783 0,0647281 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04570783 0,06469002 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04570783 0,06465199 ! cytolysis GO:0019835 24 21 0,000 0,04570783 0,06461401 ! vasodilation GO:0042311 39 21 0,000 0,04570783 0,06457607 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04570783 0,06453817 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04570783 0,06450032 ! oogenesis GO:0048477 36 21 0,000 0,04570783 0,06446251 ! DNA modification GO:0006304 34 21 0,000 0,04570783 0,06442475 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04570783 0,06438703 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04570783 0,06434935 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04570783 0,06431172 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04570783 0,06427413 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04570783 0,06423659 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04570783 0,06419909 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04570783 0,06416163 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04570783 0,06412422 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04570783 0,06408685 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04570783 0,06404953 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04570783 0,06401225 ! collagen catabolic process GO:0030574 28 21 0,000 0,04570783 0,06397501 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04570783 0,06393781 ! gut development GO:0048565 39 21 0,000 0,04570783 0,06390066 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04783228 0,06683187 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04783228 0,06679308 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04783228 0,06675434 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04783228 0,06671564 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04783228 0,06667699 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04783228 0,06663838 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04783228 0,06659981 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04783228 0,06656129 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04783228 0,06652282 ! regeneration GO:0031099 41 22 0,000 0,04783228 0,06648439 ! keratinization GO:0031424 28 22 0,000 0,04783228 0,066446 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04783228 0,06640766 ! sensory perception of taste GO:0050909 28 22 0,000 0,04783228 0,06636936 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,04783228 0,06633111 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04783228 0,0662929 ! vacuolar transport GO:0007034 36 22 0,000 0,04783228 0,06625474 ! lysosome organization GO:0007040 41 22 0,000 0,04783228 0,06621662 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04783228 0,06617854 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04783228 0,0661405 ! fucose metabolic process GO:0006004 39 22 0,000 0,04783228 0,06610251 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04783228 0,06606457 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04783228 0,06602667 ! ureteric bud development GO:0001657 43 22 0,000 0,04783228 0,06598881 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04783228 0,06595099 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04783228 0,06591322 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04783228 0,06587549 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04783228 0,0658378 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04783228 0,06580016 ! sarcomere organization GO:0045214 30 22 0,000 0,04783228 0,06576256 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04783228 0,065725 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04783228 0,06568749 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04783228 0,06565002 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04783228 0,06561259 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04783228 0,0655752 ! protein stabilization GO:0050821 39 22 0,000 0,04783228 0,06553786 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,04995208 0,06840336 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,04995208 0,06836445 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,04995208 0,06832559 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,04995208 0,06828676 ! gluconeogenesis GO:0006094 33 23 0,000 0,04995208 0,06824799 ! viral genome replication GO:0019079 41 23 0,000 0,04995208 0,06820925 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04995208 0,06817056 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04995208 0,06813192 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04995208 0,06809332 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04995208 0,06805476 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04995208 0,06801624 ! visual behavior GO:0007632 42 23 0,000 0,04995208 0,06797777 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,04995208 0,06793935 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,04995208 0,06790096 ! response to ethanol GO:0045471 46 23 0,000 0,04995208 0,06786262 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04995208 0,06782433 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,04995208 0,06778607 ! peroxisome organization GO:0007031 37 23 0,000 0,04995208 0,06774786 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04995208 0,06770969 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04995208 0,06767157 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04995208 0,06763349 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04995208 0,06759545 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,04995208 0,06755745 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04995208 0,0675195 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04995208 0,06748159 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04995208 0,06744372 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04995208 0,06740589 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04995208 0,06736811 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04995208 0,06733037 ! fatty acid transport GO:0015908 44 23 0,000 0,04995208 0,06729267 ! platelet activation GO:0030168 37 23 0,000 0,04995208 0,06725501 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,04995208 0,0672174 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04995208 0,06717982 ! hormone transport GO:0009914 40 23 0,000 0,04995208 0,06714229 ! cell-cell recognition GO:0009988 25 23 0,000 0,04995208 0,0671048 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,04995208 0,06706736 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04995208 0,06702995 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,04995208 0,06699259 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04995208 0,06695527 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04995208 0,06691799 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,05206723 0,06971271 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,05206723 0,06967394 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05206723 0,06963521 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05206723 0,06959653 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05206723 0,06955788 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05206723 0,06951928 ! spinal cord development GO:0021510 47 24 0,000 0,05206723 0,06948072 ! vacuole organization GO:0007033 43 24 0,000 0,05206723 0,06944221 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05206723 0,06940374 ! digestive system process GO:0022600 39 24 0,000 0,05206723 0,06936531 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05206723 0,06932692 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05206723 0,06928858 ! regulation of behavior GO:0050795 43 24 0,000 0,05206723 0,06925027 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05206723 0,06921201 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05206723 0,0691738 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05206723 0,06913562 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,05206723 0,06909749 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05206723 0,0690594 ! pallium development GO:0021543 49 24 0,000 0,05206723 0,06902135 ! pentose metabolic process GO:0019321 35 24 0,000 0,05206723 0,06898334 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05206723 0,06894537 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05206723 0,06890745 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05206723 0,06886957 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05206723 0,06883173 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05206723 0,06879393 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05206723 0,06875617 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05206723 0,06871846 ! regulation of amine transport GO:0051952 40 24 0,000 0,05206723 0,06868078 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05417773 0,07142555 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,05417773 0,07138643 ! myelination GO:0042552 45 25 0,000 0,05417773 0,07134736 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05417773 0,07130833 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05417773 0,07126934 ! phototransduction GO:0007602 33 25 0,000 0,05417773 0,0712304 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05417773 0,07119149 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,05417773 0,07115263 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,05417773 0,07111382 ! receptor metabolic process GO:0043112 46 25 0,000 0,05417773 0,07107504 ! chromosome condensation GO:0030261 45 25 0,000 0,05417773 0,07103631 ! response to starvation GO:0042594 42 25 0,000 0,05417773 0,07099762 ! osteoblast differentiation GO:0001649 60 25 0,000 0,05417773 0,07095897 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,05417773 0,07092036 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05417773 0,0708818 ! negative regulation of cell development GO:0010721 73 25 0,000 0,05417773 0,07084328 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05417773 0,07080479 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05417773 0,07076636 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05417773 0,07072796 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05417773 0,0706896 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,05417773 0,07065129 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05417773 0,07061302 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05417773 0,07057478 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,05417773 0,07053659 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05417773 0,07049845 ! telomere organization GO:0032200 43 25 0,000 0,05417773 0,07046034 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05417773 0,07042227 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05417773 0,07038425 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05628361 0,07308061 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05628361 0,07304119 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05628361 0,07300182 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05628361 0,07296248 ! initiation of viral infection GO:0019059 57 26 0,000 0,05628361 0,07292319 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05628361 0,07288395 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05628361 0,07284474 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05628361 0,07280558 ! molting cycle process GO:0022404 50 26 0,000 0,05628361 0,07276645 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05628361 0,07272737 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,05628361 0,07268834 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,05628361 0,07264934 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,05628361 0,07261039 GO:0045936|negative regulation of phosphate metabolic process, ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05628361 0,07257147 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,05628361 0,0725326 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05628361 0,07249377 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05628361 0,07245499 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,05628361 0,07241624 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05628361 0,07237754 ! blastocyst development GO:0001824 49 26 0,000 0,05628361 0,07233887 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05628361 0,07230025 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05628361 0,07226167 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05628361 0,07222313 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,05838487 0,07487953 ! neuron fate commitment GO:0048663 48 27 0,000 0,05838487 0,07483964 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,05838487 0,07479979 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,05838487 0,07475998 ! iron ion transport GO:0006826 59 27 0,000 0,05838487 0,07472021 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,05838487 0,07468049 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,05838487 0,07464081 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,05838487 0,07460117 ! fat cell differentiation GO:0045444 50 27 0,000 0,05838487 0,07456157 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,05838487 0,07452202 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,05838487 0,0744825 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,05838487 0,07444303 ! autophagy GO:0006914 41 27 0,000 0,05838487 0,0744036 ! male gonad development GO:0008584 44 27 0,000 0,05838487 0,07436421 ! response to toxin GO:0009636 47 27 0,000 0,05838487 0,07432487 ! primary neural tube formation GO:0014020 51 27 0,000 0,05838487 0,07428556 ! base-excision repair GO:0006284 41 27 0,000 0,05838487 0,0742463 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,05838487 0,07420708 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,05838487 0,0741679 ! glutathione metabolic process GO:0006749 39 27 0,000 0,05838487 0,07412876 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,05838487 0,07408966 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,05838487 0,07405061 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,05838487 0,07401159 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,05838487 0,07397262 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06048152 0,07658871 ! circadian rhythm GO:0007623 50 28 0,000 0,06048152 0,07654842 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06048152 0,07650817 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,06048152 0,07646797 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06048152 0,07642781 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,06048152 0,07638769 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06048152 0,07634761 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06048152 0,07630757 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,06048152 0,07626758 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,06048152 0,07622763 ! synaptogenesis GO:0007416 42 28 0,000 0,06048152 0,07618772 ! lipid oxidation GO:0034440 43 28 0,000 0,06048152 0,07614785 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,06048152 0,07610802 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,06048152 0,07606824 ! translational initiation GO:0006413 65 29 0,000 0,06257357 0,07865832 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,06257357 0,07861724 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06257357 0,07857621 ! regulation of pH GO:0006885 43 29 0,000 0,06257357 0,07853522 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06257357 0,07849427 ! catechol metabolic process GO:0009712 54 29 0,000 0,06257357 0,07845337 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,06257357 0,07841251 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,06257357 0,07837169 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,06257357 0,07833091 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,06257357 0,07829018 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,06257357 0,07824949 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,06257357 0,07820884 ! cell fate determination GO:0001709 60 29 0,000 0,06257357 0,07816823 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06257357 0,07812767 ! detection of light stimulus GO:0009583 38 29 0,000 0,06257357 0,07808715 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,06257357 0,07804667 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,06257357 0,07800623 ! tissue homeostasis GO:0001894 48 29 0,000 0,06257357 0,07796583 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,06466104 0,08052508 ! zinc ion transport GO:0006829 45 30 0,000 0,06466104 0,08048342 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,06466104 0,08044181 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06466104 0,08040023 ! acute-phase response GO:0006953 49 30 0,000 0,06466104 0,0803587 ! myofibril assembly GO:0030239 47 30 0,000 0,06466104 0,08031722 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06466104 0,08027578 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06466104 0,08023437 ! phospholipid transport GO:0015914 51 30 0,000 0,06466104 0,08019302 ! ensheathment of neurons GO:0007272 57 30 0,000 0,06466104 0,0801517 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06466104 0,08011043 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,06466104 0,0800692 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,06466104 0,08002801 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06466104 0,07998686 ! eye morphogenesis GO:0048592 60 30 0,000 0,06466104 0,07994576 ! regulation of B cell activation GO:0050864 50 30 0,000 0,06466104 0,0799047 ! response to heat GO:0009408 50 30 0,000 0,06466104 0,07986368 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06674392 0,08239398 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06674392 0,08235173 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06674392 0,08230952 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06674392 0,08226735 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06674392 0,08222523 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06674392 0,08218315 ! ovulation cycle process GO:0022602 49 31 0,000 0,06674392 0,08214111 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06674392 0,08209912 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,06674392 0,08205716 ! peptide transport GO:0015833 55 31 0,000 0,06674392 0,08201526 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,06674392 0,08197339 ! mesoderm formation GO:0001707 69 31 0,000 0,06674392 0,08193157 ! natural killer cell activation GO:0030101 45 31 0,000 0,06674392 0,08188979 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06674392 0,08184805 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06674392 0,08180635 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06674392 0,0817647 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06674392 0,08172309 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06674392 0,08168152 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06882223 0,08418215 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,06882223 0,08413938 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,06882223 0,08409664 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06882223 0,08405396 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06882223 0,08401131 ! spliceosome assembly GO:0000245 67 32 0,000 0,06882223 0,08396871 ! spindle organization GO:0007051 46 32 0,000 0,06882223 0,08392615 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,06882223 0,08388363 ! metanephros development GO:0001656 74 32 0,000 0,06882223 0,08384116 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,06882223 0,08379873 ! response to ionizing radiation GO:0010212 65 32 0,000 0,06882223 0,08375634 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,06882223 0,083714 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,06882223 0,0836717 ! muscle cell development GO:0055001 49 32 0,000 0,06882223 0,08362944 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06882223 0,08358723 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,06882223 0,08354505 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06882223 0,08350292 ! ovulation cycle GO:0042698 51 32 0,000 0,06882223 0,08346083 ! peripheral nervous system development GO:0007422 64 32 0,000 0,06882223 0,08341879 ! BMP signaling pathway GO:0030509 64 32 0,000 0,06882223 0,08337678 ! hindbrain development GO:0030902 61 32 0,000 0,06882223 0,08333482 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,06882223 0,0832929 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06882223 0,08325103 ! gene silencing GO:0016458 65 32 0,000 0,06882223 0,08320919 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,07089599 0,0856734 ! post-embryonic development GO:0009791 69 33 0,000 0,07089599 0,0856304 ! protein targeting to membrane GO:0006612 68 33 0,000 0,07089599 0,08558743 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,07089599 0,08554451 ! ceramide metabolic process GO:0006672 64 33 0,000 0,07089599 0,08550163 ! formation of primary germ layer GO:0001704 72 33 0,000 0,07089599 0,08545879 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,07089599 0,085416 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,07089599 0,08537325 ! adult locomotory behavior GO:0008344 59 33 0,000 0,07089599 0,08533054 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,07089599 0,08528787 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,07089599 0,08524525 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,07296519 0,08768944 ! glial cell differentiation GO:0010001 63 34 0,000 0,07296519 0,08764566 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,07296519 0,08760192 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07296519 0,08755823 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07296519 0,08751458 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,07296519 0,08747098 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,07296519 0,08742742 ! spermatid development GO:0007286 63 34 0,000 0,07296519 0,0873839 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,07296519 0,08734043 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07296519 0,08729699 ! regulation of muscle development GO:0048634 70 35 0,000 0,07502986 0,08972258 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,07502986 0,08967801 ! negative regulation of secretion GO:0051048 63 35 0,000 0,07502986 0,08963349 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,07502986 0,089589 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,07502986 0,08954456 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,07502986 0,08950017 ! odontogenesis GO:0042476 66 35 0,000 0,07502986 0,08945582 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,07502986 0,08941151 ! female gonad development GO:0008585 58 35 0,000 0,07502986 0,08936725 ! telencephalon development GO:0021537 68 35 0,000 0,07502986 0,08932303 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,07502986 0,08927885 ! cytokine production GO:0001816 59 35 0,000 0,07502986 0,08923472 ! neural tube formation GO:0001841 67 35 0,000 0,07502986 0,08919063 ! vesicle localization GO:0051648 64 35 0,000 0,07502986 0,08914659 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,07708999 0,09154912 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,07708999 0,09150396 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,07708999 0,09145884 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,07708999 0,09141376 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,07708999 0,09136873 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,07708999 0,09132374 ! positive regulation of cell development GO:0010720 80 36 0,000 0,07708999 0,0912788 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,07708999 0,0912339 ! regulation of proteolysis GO:0030162 72 36 0,000 0,07708999 0,09118905 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,07708999 0,09114424 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,07708999 0,09109947 ! aerobic respiration GO:0009060 55 36 0,000 0,07708999 0,09105475 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,07708999 0,09101007 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,07708999 0,09096544 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,07708999 0,09092085 ! RNA export from nucleus GO:0006405 56 37 0,000 0,07914561 0,09329953 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,07914561 0,09325384 ! meiosis I GO:0007127 65 37 0,000 0,07914561 0,09320819 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,07914561 0,09316259 ! sister chromatid segregation GO:0000819 58 37 0,000 0,07914561 0,09311704 ! actomyosin structure organization GO:0031032 62 37 0,000 0,07914561 0,09307152 ! organic anion transport GO:0015711 68 37 0,000 0,07914561 0,09302606 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,07914561 0,09298063 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,07914561 0,09293525 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,07914561 0,09288992 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,07914561 0,09284463 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,07914561 0,09279938 ! pigment metabolic process GO:0042440 80 37 0,000 0,07914561 0,09275418 ! spermatid differentiation GO:0048515 66 37 0,000 0,07914561 0,09270902 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,08119671 0,09506535 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,08119671 0,09501911 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,08119671 0,09497292 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,08119671 0,09492677 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,08119671 0,09488067 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,08119671 0,09483461 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,08119671 0,0947886 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,08119671 0,09474263 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,08119671 0,0946967 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,08119671 0,09465082 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,08119671 0,09460499 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,08119671 0,09455919 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,08119671 0,09451345 ! mRNA catabolic process GO:0006402 71 39 0,000 0,08324332 0,09684885 ! learning GO:0007612 77 39 0,000 0,08324332 0,09680204 ! ear morphogenesis GO:0042471 60 39 0,000 0,08324332 0,09675528 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,08324332 0,09670856 ! ion transmembrane transport GO:0034220 66 39 0,000 0,08324332 0,09666189 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,08324332 0,09661526 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,08324332 0,09656867 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,08324332 0,09652213 ! RNA modification GO:0009451 57 39 0,000 0,08324332 0,09647564 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,08324332 0,09642919 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,08528543 0,09874723 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,08528543 0,09869974 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08528543 0,09865228 ! feeding behavior GO:0007631 59 40 0,000 0,08528543 0,09860488 ! negative regulation of binding GO:0051100 72 40 0,000 0,08528543 0,09855752 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08528543 0,0985102 ! maintenance of protein location GO:0045185 91 40 0,000 0,08528543 0,09846293 ! cytokinesis GO:0000910 72 40 0,000 0,08528543 0,09841571 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08732307 0,10071874 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08732307 0,10067048 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08732307 0,10062227 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08732307 0,1005741 ! gliogenesis GO:0042063 88 41 0,000 0,08732307 0,10052598 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,08732307 0,1004779 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,08732307 0,10042987 ! T cell differentiation GO:0030217 81 41 0,000 0,08732307 0,10038189 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,08732307 0,10033395 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,08732307 0,10028606 ! female gamete generation GO:0007292 61 41 0,000 0,08732307 0,10023821 ! polyol metabolic process GO:0019751 66 41 0,000 0,08732307 0,10019041 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,08732307 0,10014266 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,08935623 0,10242548 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,08935623 0,10237671 ! regulation of tube size GO:0035150 71 42 0,000 0,08935623 0,10232798 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,08935623 0,1022793 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,08935623 0,10223066 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,08935623 0,10218207 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,08935623 0,10213353 ! neuron migration GO:0001764 79 42 0,000 0,08935623 0,10208503 ! regulation of protein secretion GO:0050708 71 42 0,000 0,08935623 0,10203658 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,09138493 0,10430367 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,09138493 0,10425421 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,09138493 0,1042048 ! glucose transport GO:0015758 65 43 0,000 0,09138493 0,10415544 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,09138493 0,10410612 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,09138493 0,10405685 ! neural tube development GO:0021915 77 43 0,000 0,09138493 0,10400763 ! striated muscle contraction GO:0006941 77 43 0,000 0,09138493 0,10395846 ! phagocytosis GO:0006909 90 43 0,000 0,09138493 0,10390933 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,09138493 0,10386024 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,09340917 0,1061107 ! hexose transport GO:0008645 67 44 0,000 0,09340917 0,10606063 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,09340917 0,1060106 ! male sex differentiation GO:0046661 76 44 0,000 0,09340917 0,10596062 ! double-strand break repair GO:0006302 81 44 0,000 0,09340917 0,10591068 ! biopolymer methylation GO:0043414 84 44 0,000 0,09340917 0,1058608 ! B cell differentiation GO:0030183 107 44 0,000 0,09340917 0,10581096 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,09340917 0,10576116 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,09340917 0,10571142 ! developmental growth GO:0048589 82 44 0,000 0,09340917 0,10566172 ! maintenance of location in cell GO:0051651 97 44 0,000 0,09340917 0,10561206 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09542898 0,10784505 ! glycolysis GO:0006096 65 45 0,000 0,09542898 0,10779442 ! leukocyte migration GO:0050900 68 45 0,000 0,09542898 0,10774384 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,09542898 0,1076933 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,09542898 0,10764281 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09542898 0,10759237 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09542898 0,10754198 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09542898 0,10749163 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09542898 0,10744133 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,09744435 0,10965908 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,09744435 0,10960781 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,09744435 0,10955659 ! pigmentation GO:0043473 100 46 0,000 0,09744435 0,10950542 ! positive regulation of defense response GO:0031349 76 47 0,000 0,0994553 0,11171309 ! response to calcium ion GO:0051592 81 47 0,000 0,0994553 0,11166096 ! endosome transport GO:0016197 108 47 0,000 0,0994553 0,11160888 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,0994553 0,11155685 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,0994553 0,11150487 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,0994553 0,11145293 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,0994553 0,11140105 ! methylation GO:0032259 90 47 0,000 0,0994553 0,11134921 ! mitochondrial transport GO:0006839 82 48 0,000 0,10146183 0,11354287 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,10146183 0,11349008 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,10146183 0,11343735 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,10146183 0,11338466 ! activation of caspase activity GO:0006919 84 48 0,000 0,10146183 0,11333202 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,10146183 0,11327943 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,10146183 0,11322689 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,10146183 0,11317439 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,10146183 0,11312195 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,10346396 0,11530074 ! regulation of action potential GO:0001508 95 49 0,000 0,10346396 0,11524736 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,10346396 0,11519403 ! regulation of ion transport GO:0043269 77 49 0,000 0,10346396 0,11514075 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,10346396 0,11508752 ! peptide metabolic process GO:0006518 76 49 0,000 0,10346396 0,11503433 ! response to temperature stimulus GO:0009266 76 49 0,000 0,10346396 0,1149812 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,10346396 0,11492811 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,10346396 0,11487508 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,10346396 0,11482209 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,10346396 0,11476915 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,10346396 0,11471627 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,1054617 0,11687741 ! neuromuscular process GO:0050905 99 50 0,000 0,1054617 0,11682359 ! regulation of ossification GO:0030278 117 50 0,000 0,1054617 0,11676983 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,1054617 0,11671612 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,1054617 0,11666246 ! viral infectious cycle GO:0019058 99 51 0,000 0,10745505 0,11881289 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,10745505 0,11875831 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,10745505 0,11870379 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,10745505 0,11864931 ! excretion GO:0007588 83 51 0,000 0,10745505 0,11859488 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,10745505 0,11854051 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,10745505 0,11848618 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,10745505 0,1184319 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,10745505 0,11837768 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,10745505 0,1183235 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,10745505 0,11826937 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,10944402 0,12040344 ! amino acid activation GO:0043038 92 52 0,000 0,10944402 0,12034841 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,10944402 0,12029343 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,11142863 0,12241885 ! RNA catabolic process GO:0006401 93 53 0,000 0,11142863 0,12236298 ! regulation of translational initiation GO:0006446 82 53 0,000 0,11142863 0,12230716 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,11142863 0,12225139 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,11142863 0,12219567 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,11142863 0,12214 ! cell maturation GO:0048469 100 53 0,000 0,11142863 0,12208438 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,11142863 0,12202881 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,11340888 0,12414093 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,11340888 0,12408448 ! cell recognition GO:0008037 85 54 0,000 0,11340888 0,12402808 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,11340888 0,12397173 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,11340888 0,12391543 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,11340888 0,12385918 ! chloride transport GO:0006821 90 55 0,000 0,11538479 0,12595998 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,11538479 0,12590286 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,11538479 0,12584578 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,11538479 0,12578876 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,11538479 0,12573179 ! aging GO:0007568 103 55 0,000 0,11538479 0,12567488 ! gastrulation GO:0007369 112 55 0,000 0,11538479 0,12561801 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,11538479 0,12556119 ! RNA elongation GO:0006354 79 55 0,000 0,11538479 0,12550443 ! nuclear export GO:0051168 97 55 0,000 0,11538479 0,12544772 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,11538479 0,12539106 ! regulation of actin filament length GO:0030832 105 56 0,000 0,11735635 0,12747602 ! sensory perception of smell GO:0007608 80 56 0,000 0,11735635 0,1274185 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,11735635 0,12736102 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,11735635 0,1273036 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,11735635 0,12724623 ! proton transport GO:0015992 94 56 0,000 0,11735635 0,12718891 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,11932359 0,12926275 ! muscle fiber development GO:0048747 112 57 0,000 0,11932359 0,12920457 ! lipid modification GO:0030258 97 57 0,000 0,11932359 0,12914645 ! maintenance of location GO:0051235 118 57 0,000 0,11932359 0,12908838 ! hydrogen transport GO:0006818 97 58 0,000 0,12128651 0,13115296 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,12128651 0,13109404 ! regulation of endocytosis GO:0030100 91 58 0,000 0,12128651 0,13103518 ! adult behavior GO:0030534 99 58 0,000 0,12128651 0,13097637 ! positive regulation of secretion GO:0051047 95 59 0,000 0,12324512 0,13303174 ! regulation of cellular component size GO:0032535 109 59 0,000 0,12324512 0,13297209 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,12324512 0,13291248 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,12324512 0,13285294 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,12324512 0,13279344 ! DNA catabolic process GO:0006308 86 59 0,000 0,12324512 0,132734 ! establishment of organelle localization GO:0051656 109 59 0,000 0,12324512 0,13267461 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,12519943 0,13471817 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,12519943 0,13465794 ! regulation of heart contraction GO:0008016 110 60 0,000 0,12519943 0,13459777 ! camera-type eye development GO:0043010 116 60 0,000 0,12519943 0,13453766 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,12519943 0,1344776 ! kidney development GO:0001822 122 60 0,000 0,12519943 0,13441759 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,12714944 0,13645029 ! mesoderm development GO:0007498 119 61 0,000 0,12714944 0,13638946 ! tRNA processing GO:0008033 89 61 0,000 0,12714944 0,13632868 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,12714944 0,13626795 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,12909518 0,13829163 ! gonad development GO:0008406 98 62 0,000 0,12909518 0,13823008 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,13103664 0,14024651 ! detection of external stimulus GO:0009581 91 63 0,000 0,13103664 0,14018415 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,13103664 0,14012184 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,13103664 0,1400596 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,13297384 0,14206707 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,13297384 0,14200402 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,13297384 0,14194101 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,13297384 0,14187807 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,13490678 0,14387664 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,13490678 0,1438129 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,13490678 0,14374921 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,13490678 0,14368557 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,13490678 0,143622 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,13683548 0,14561086 ! actin filament organization GO:0007015 148 66 0,000 0,13683548 0,14554649 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,13683548 0,14548217 ! extracellular matrix organization GO:0030198 133 66 0,000 0,13683548 0,14541791 ! secondary metabolic process GO:0019748 116 66 0,000 0,13683548 0,14535371 ! developmental maturation GO:0021700 116 66 0,000 0,13683548 0,14528957 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,13875994 0,14726794 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,13875994 0,147203 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,13875994 0,14713813 ! chromosome segregation GO:0007059 113 67 0,000 0,13875994 0,14707331 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,13875994 0,14700855 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,13875994 0,14694384 ! hexose catabolic process GO:0019320 104 67 0,000 0,13875994 0,1468792 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,13875994 0,14681461 ! adaptive immune response GO:0002250 119 67 0,000 0,13875994 0,14675007 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,13875994 0,1466856 ! amino acid transport GO:0006865 125 68 0,000 0,14068018 0,1486502 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,14068018 0,14858494 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,14068018 0,14851975 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,14068018 0,14845461 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,14068018 0,14838952 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,14068018 0,1483245 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,14259619 0,15027877 ! negative regulation of cell size GO:0045792 134 69 0,000 0,14259619 0,15021298 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,14259619 0,15014724 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,14259619 0,15008156 ! urogenital system development GO:0001655 137 69 0,000 0,14259619 0,15001593 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,14259619 0,14995037 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,14259619 0,14988486 ! antigen processing and presentation GO:0019882 104 69 0,000 0,14259619 0,14981941 ! appendage morphogenesis GO:0035107 135 70 0,000 0,144508 0,15176179 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,14641561 0,15369807 ! reproductive structure development GO:0048608 113 71 0,000 0,14641561 0,15363104 ! appendage development GO:0048736 136 71 0,000 0,14641561 0,15356407 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,14641561 0,15349715 ! B cell activation GO:0042113 160 71 0,000 0,14641561 0,1534303 ! regulation of immune effector process GO:0002697 137 71 0,000 0,14641561 0,1533635 ! acute inflammatory response GO:0002526 113 72 0,000 0,14831903 0,15528964 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,14831903 0,15522209 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,14831903 0,15515461 ! carbohydrate transport GO:0008643 110 72 0,000 0,14831903 0,15508718 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,14831903 0,15501981 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,14831903 0,15495249 ! regulation of blood pressure GO:0008217 125 73 0,000 0,15021827 0,15686856 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,15021827 0,1568005 ! axon guidance GO:0007411 139 73 0,000 0,15021827 0,15673251 ! fertilization GO:0009566 90 73 0,000 0,15021827 0,15666457 ! transition metal ion transport GO:0000041 126 74 0,000 0,15211334 0,15857222 ! neurotransmitter transport GO:0006836 123 74 0,000 0,15211334 0,15850355 ! meiosis GO:0007126 121 74 0,000 0,15211334 0,15843493 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,15211334 0,15836637 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,15211334 0,15829788 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,15211334 0,15822944 ! eye development GO:0001654 143 74 0,000 0,15211334 0,15816106 ! organelle localization GO:0051640 136 74 0,000 0,15211334 0,15809274 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,15400424 0,15998886 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,15400424 0,15991981 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,15400424 0,15985082 ! meiotic cell cycle GO:0051321 122 75 0,000 0,15400424 0,15978189 ! rhythmic process GO:0048511 128 75 0,000 0,15400424 0,15971302 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,15400424 0,15964421 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,15589099 0,16153046 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,15589099 0,16146092 ! defense response to bacterium GO:0042742 89 76 0,000 0,15589099 0,16139145 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,15589099 0,16132203 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,15589099 0,16125268 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,15777359 0,1631299 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,15777359 0,16305982 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,15777359 0,16298981 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,15777359 0,16291986 ! blood coagulation GO:0007596 146 78 0,000 0,15965206 0,16478887 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,15965206 0,16471821 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,15965206 0,1646476 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,1615264 0,16650922 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,1615264 0,16643791 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,1615264 0,16636666 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,1615264 0,16629547 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,16339662 0,16814896 ! response to metal ion GO:0010038 140 80 0,000 0,16339662 0,16807708 ! muscle cell differentiation GO:0042692 159 80 0,000 0,16339662 0,16800525 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,16339662 0,16793348 ! protein import into nucleus GO:0006606 158 80 0,000 0,16339662 0,16786178 ! inorganic anion transport GO:0015698 138 80 0,000 0,16339662 0,16779013 ! T cell activation GO:0042110 168 81 0,000 0,16526274 0,16963402 ! digestion GO:0007586 112 81 0,000 0,16526274 0,16956168 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,16526274 0,16948941 ! nuclear import GO:0051170 161 81 0,000 0,16526274 0,16941719 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,16526274 0,16934504 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,16712475 0,17118014 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,16712475 0,1711073 ! response to drug GO:0042493 143 82 0,000 0,16712475 0,17103452 ! response to nutrient GO:0007584 125 82 0,000 0,16712475 0,1709618 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,16712475 0,17088914 ! regulation of lyase activity GO:0051339 160 83 0,000 0,16898267 0,17271551 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,17083651 0,17453615 ! hemostasis GO:0007599 158 84 0,000 0,17083651 0,17446207 ! negative regulation of transport GO:0051051 153 84 0,000 0,17083651 0,17438805 ! regulation of ligase activity GO:0051340 142 84 0,000 0,17083651 0,1743141 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,17083651 0,1742402 ! response to unfolded protein GO:0006986 131 85 0,000 0,17268627 0,17605219 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,17268627 0,17597762 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,17268627 0,17590312 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,17453197 0,17770796 ! response to inorganic substance GO:0010035 153 86 0,000 0,17453197 0,17763279 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,17453197 0,17755768 ! tube morphogenesis GO:0035239 176 86 0,000 0,17453197 0,17748264 ! mitochondrion organization GO:0007005 148 86 0,000 0,17453197 0,17740766 ! alcohol catabolic process GO:0046164 130 86 0,000 0,17453197 0,17733274 ! amine transport GO:0015837 155 86 0,000 0,17453197 0,17725788 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,17637361 0,1790527 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,17637361 0,17897719 ! protein localization in nucleus GO:0034504 176 87 0,000 0,17637361 0,17890173 ! cellular respiration GO:0045333 135 88 0,000 0,17821121 0,18068949 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,17821121 0,18061338 ! regulation of neurological system process GO:0031644 148 88 0,000 0,17821121 0,18053733 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,17821121 0,18046135 ! cellular defense response GO:0006968 114 89 0,000 0,18004476 0,18224135 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,18004476 0,18216472 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,18004476 0,18208815 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,18187429 0,18386115 ! sex differentiation GO:0007548 145 90 0,000 0,18187429 0,18378393 ! sterol metabolic process GO:0016125 152 91 0,000 0,18369979 0,18555067 ! response to protein stimulus GO:0051789 149 91 0,000 0,18369979 0,18547281 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,18369979 0,18539501 ! regulation of defense response GO:0031347 149 92 0,000 0,18552128 0,18715481 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,18552128 0,18707637 ! vitamin metabolic process GO:0006766 139 92 0,000 0,18552128 0,18699799 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,18733877 0,18875087 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,18733877 0,18867187 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,18915227 0,19041856 ! female pregnancy GO:0007565 164 94 0,000 0,18915227 0,19033892 ! transcription initiation GO:0006352 153 94 0,000 0,18915227 0,19025934 ! regulation of T cell activation GO:0050863 158 94 0,000 0,18915227 0,19017984 ! forebrain development GO:0030900 188 95 0,000 0,19096177 0,19191897 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,19096177 0,19183884 ! leukocyte differentiation GO:0002521 202 96 0,000 0,1927673 0,19357184 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,1927673 0,19349108 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,1927673 0,19341039 ! detection of stimulus GO:0051606 151 96 0,000 0,1927673 0,19332977 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,19456886 0,19505528 ! protein ubiquitination GO:0016567 217 97 0,000 0,19456886 0,19497404 ! hormone metabolic process GO:0042445 157 97 0,000 0,19456886 0,19489287 ! response to virus GO:0009615 160 98 0,000 0,19636646 0,19661161 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,19636646 0,19652982 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,19636646 0,1964481 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,1981601 0,1981601