pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1123-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! ribosomal large subunit biogenesis GO:0042273 12 12 3,000 1,206E-07 2,774E-04 ! nuclear migration GO:0007097 10 5 2,000 6,382E-07 7,34E-04 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 6,382E-07 4,893E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of respiratory burst GO:0060263 8 5 2,000 6,382E-07 3,67E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 3,000 1,152E-06 5,299E-04 ! macrophage differentiation GO:0030225 10 6 2,000 1,273E-06 4,879E-04 ! regulation of lipid kinase activity GO:0043550 12 7 2,000 2,221E-06 7,297E-04 ! establishment of nucleus localization GO:0040023 13 7 2,000 2,221E-06 6,385E-04 ! nucleus localization GO:0051647 15 9 2,000 5,299E-06 1,354E-03 ! regulation of cell projection assembly GO:0060491 20 10 2,000 7,548E-06 1,736E-03 ! filopodium assembly GO:0046847 19 11 2,000 1,035E-05 2,164E-03 ! microspike assembly GO:0030035 23 12 2,000 1,376E-05 2,637E-03 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 3,000 3,904E-05 6,908E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 4,191E-05 6,884E-03 ! RNA elongation GO:0006354 62 49 3,000 4,61E-05 7,068E-03 ! regulation of protein complex assembly GO:0043254 81 54 3,000 6,776E-05 9,74E-03 ! regulation of lipid metabolic process GO:0019216 84 56 3,000 7,822E-05 0,01058206 ! myeloid leukocyte differentiation GO:0002573 33 21 2,000 8,101E-05 0,01035143 ! response to molecule of bacterial origin GO:0002237 30 23 2,000 1,072E-04 0,0129824 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 1,222E-04 0,01405418 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 1,222E-04 0,01338493 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 2,000 1,222E-04 0,01277653 ! protein oligomerization GO:0051259 100 65 3,000 1,403E-04 0,01402644 ! positive regulation of glycolysis GO:0045821 11 5 1,000 1,613E-04 0,01546263 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 1,613E-04 0,01484413 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 1,613E-04 0,0142732 GO:0045686|negative regulation of glial cell differentiation, ! negative regulation of T cell mediated immunity GO:0002710 11 5 1,000 1,613E-04 0,01374456 GO:0002707|negative regulation of lymphocyte mediated immunity, ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 1,000 1,613E-04 0,01325368 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 1,000 1,613E-04 0,01279666 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 1,000 1,613E-04 0,01237011 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! positive regulation of microtubule polymerization GO:0031116 9 5 1,000 1,613E-04 0,01197107 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 3,000 1,871E-04 0,01344611 ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 1,955E-04 0,01362687 ! response to hypoxia GO:0001666 132 72 3,000 2,086E-04 0,01411308 ! response to oxygen levels GO:0070482 137 74 3,000 2,319E-04 0,0152401 ! positive regulation of immune effector process GO:0002699 40 30 2,000 2,409E-04 0,01539081 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 2,414E-04 0,01500517 ! opsonization GO:0008228 8 6 1,000 2,414E-04 0,01461029 ! thymic T cell selection GO:0045061 12 6 1,000 2,414E-04 0,01423567 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 1,000 2,414E-04 0,01387978 ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 2,414E-04 0,01354125 ! male sex determination GO:0030238 9 6 1,000 2,414E-04 0,01321884 ! gas homeostasis GO:0033483 11 6 1,000 2,414E-04 0,01291142 ! regulation of macrophage activation GO:0043030 11 6 1,000 2,414E-04 0,01261798 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 1,000 2,414E-04 0,01233758 ! regulation of microtubule polymerization GO:0031113 11 6 1,000 2,414E-04 0,01206937 ! positive regulation of DNA metabolic process GO:0051054 54 33 2,000 3,209E-04 0,01570448 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,371E-04 0,01615051 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 1,000 3,371E-04 0,01582091 ! positive regulation of isotype switching GO:0045830 15 7 1,000 3,371E-04 0,01550449 GO:0045911|positive regulation of DNA recombination, ! vesicle fusion GO:0006906 15 7 1,000 3,371E-04 0,01520048 ! protein heterooligomerization GO:0051291 10 7 1,000 3,371E-04 0,01490816 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 1,000 3,371E-04 0,01462688 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 1,000 3,371E-04 0,01435601 GO:0002714|positive regulation of B cell mediated immunity, ! neuroblast proliferation GO:0007405 13 7 1,000 3,371E-04 0,01409499 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 1,000 3,371E-04 0,01384329 ! peptidyl-threonine modification GO:0018210 18 7 1,000 3,371E-04 0,01360043 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 1,000 3,371E-04 0,01336594 ! B cell receptor signaling pathway GO:0050853 11 7 1,000 3,371E-04 0,0131394 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 1,000 3,371E-04 0,01292041 ! defense response to Gram-negative bacterium GO:0050829 9 7 1,000 3,371E-04 0,0127086 ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 3,51E-04 0,01301918 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 3,51E-04 0,01281253 ! protein homooligomerization GO:0051260 52 35 2,000 3,827E-04 0,01375468 ! rRNA metabolic process GO:0016072 107 85 3,000 3,946E-04 0,01396393 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 3,946E-04 0,01375236 ! transcription initiation GO:0006352 118 85 3,000 3,946E-04 0,0135471 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 4,126E-04 0,01395636 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 4,482E-04 0,01494082 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 4,482E-04 0,01472738 ! L-phenylalanine metabolic process GO:0006558 8 8 1,000 4,482E-04 0,01451995 GO:0006559|L-phenylalanine catabolic process, ! macrophage activation GO:0042116 12 8 1,000 4,482E-04 0,01431828 ! regulation of gliogenesis GO:0014013 20 8 1,000 4,482E-04 0,01412214 GO:0045685|regulation of glial cell differentiation, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 4,482E-04 0,0139313 ! induction of an organ GO:0001759 11 8 1,000 4,482E-04 0,01374555 ! leukocyte activation during immune response GO:0002366 13 8 1,000 4,482E-04 0,01356469 GO:0002263|cell activation during immune response, ! regulation of embryonic development GO:0045995 16 8 1,000 4,482E-04 0,01338853 ! interphase GO:0051325 159 88 3,000 4,503E-04 0,0132795 ! phagocytosis GO:0006909 60 38 2,000 4,89E-04 0,01423778 ! leukocyte differentiation GO:0002521 143 90 3,000 4,905E-04 0,0141011 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 5,553E-04 0,01576908 ! regulation of developmental growth GO:0048638 13 9 1,000 5,748E-04 0,01612173 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 5,748E-04 0,01592749 ! regulation of epithelial cell differentiation GO:0030856 13 9 1,000 5,748E-04 0,01573788 ! regulation of glycolysis GO:0006110 15 9 1,000 5,748E-04 0,01555273 ! T cell selection GO:0045058 18 9 1,000 5,748E-04 0,01537188 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 1,000 5,748E-04 0,0151952 GO:0002820|negative regulation of adaptive immune response, ! defense response to Gram-positive bacterium GO:0050830 10 9 1,000 5,748E-04 0,01502252 ! positive regulation of protein polymerization GO:0032273 15 9 1,000 5,748E-04 0,01485373 ! localization within membrane GO:0051668 15 9 1,000 5,748E-04 0,01468869 ! positive regulation of DNA binding GO:0043388 57 41 2,000 6,126E-04 0,01548326 ! regulation of cellular component biogenesis GO:0044087 158 96 3,000 6,261E-04 0,0156525 ! positive regulation of binding GO:0051099 59 43 2,000 7,051E-04 0,01743777 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 7,051E-04 0,01725226 ! response to insulin stimulus GO:0032868 63 43 2,000 7,051E-04 0,01707065 ! regulation of B cell proliferation GO:0030888 15 10 1,000 7,166E-04 0,0171681 ! hippocampus development GO:0021766 19 10 1,000 7,166E-04 0,01699111 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 7,166E-04 0,01681773 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 7,166E-04 0,01664785 ! regulation of B cell differentiation GO:0045577 16 10 1,000 7,166E-04 0,01648138 ! positive regulation of interleukin-6 production GO:0032755 13 10 1,000 7,166E-04 0,01631819 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 1,000 7,166E-04 0,01615821 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 7,166E-04 0,01600134 ! positive regulation of acute inflammatory response GO:0002675 14 10 1,000 7,166E-04 0,01584748 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 7,166E-04 0,01569655 GO:0043470|regulation of carbohydrate catabolic process, ! developmental induction GO:0031128 13 10 1,000 7,166E-04 0,01554847 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 1,000 7,166E-04 0,01540316 ! negative regulation of immune effector process GO:0002698 16 10 1,000 7,166E-04 0,01526053 ! regulation of cell projection organization GO:0031344 83 44 2,000 7,545E-04 0,01592043 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 8,06E-04 0,01685353 ! virus-host interaction GO:0019048 17 11 1,000 8,735E-04 0,01810001 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 8,735E-04 0,01793841 ! T cell proliferation GO:0042098 20 11 1,000 8,735E-04 0,01777966 ! positive regulation of T cell mediated immunity GO:0002711 18 11 1,000 8,735E-04 0,0176237 ! regulation of interleukin-8 production GO:0032677 17 11 1,000 8,735E-04 0,01747045 ! regulation of isotype switching GO:0045191 19 11 1,000 8,735E-04 0,01731984 ! aromatic amino acid family catabolic process GO:0009074 13 11 1,000 8,735E-04 0,01717181 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 1,045E-03 0,02037791 ! tyrosine metabolic process GO:0006570 14 12 1,000 1,045E-03 0,02020667 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 1,045E-03 0,02003828 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 1,045E-03 0,01987268 ! gland morphogenesis GO:0022612 23 12 1,000 1,045E-03 0,01970979 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,045E-03 0,01954954 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 1,163E-03 0,02156265 ! positive regulation of cell migration GO:0030335 92 51 2,000 1,163E-03 0,02139015 ! establishment of organelle localization GO:0051656 85 52 2,000 1,23E-03 0,02245437 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,232E-03 0,02231761 ! positive regulation of protein complex assembly GO:0031334 19 13 1,000 1,232E-03 0,02214325 ! regulation of cell-cell adhesion GO:0022407 27 13 1,000 1,232E-03 0,0219716 ! lipid localization GO:0010876 24 13 1,000 1,232E-03 0,02180258 GO:0019915|lipid storage, ! organelle fusion GO:0048284 28 13 1,000 1,232E-03 0,02163615 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 1,000 1,232E-03 0,02147224 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 1,232E-03 0,0213108 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 1,232E-03 0,02115176 ! regulation of acute inflammatory response GO:0002673 19 13 1,000 1,232E-03 0,02099508 ! cell projection assembly GO:0030031 76 53 2,000 1,3E-03 0,02198765 ! regulation of S phase GO:0033261 18 14 1,000 1,434E-03 0,02407336 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,434E-03 0,02389892 ! limbic system development GO:0021761 25 14 1,000 1,434E-03 0,02372698 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 1,000 1,434E-03 0,02355751 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 1,000 1,434E-03 0,02339043 ! T cell differentiation in the thymus GO:0033077 27 14 1,000 1,434E-03 0,02322571 ! positive regulation of cell motion GO:0051272 99 56 2,000 1,525E-03 0,02453012 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 1,605E-03 0,02563867 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 1,605E-03 0,02546186 ! lipid phosphorylation GO:0046834 23 15 1,000 1,65E-03 0,02599633 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 1,000 1,65E-03 0,02581948 ! regulation of vasodilation GO:0042312 24 15 1,000 1,65E-03 0,02564502 ! regulation of T cell mediated immunity GO:0002709 26 15 1,000 1,65E-03 0,02547291 ! defense response to virus GO:0051607 27 15 1,000 1,65E-03 0,02530309 ! negative regulation of kinase activity GO:0033673 100 58 2,000 1,688E-03 0,02570916 ! viral reproductive process GO:0022415 87 58 2,000 1,688E-03 0,02554002 ! activation of MAPK activity GO:0000187 84 59 2,000 1,773E-03 0,02665503 ! lung development GO:0030324 94 59 2,000 1,773E-03 0,02648195 ! myeloid cell differentiation GO:0030099 85 59 2,000 1,773E-03 0,02631109 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,881E-03 0,0277327 ! protein amino acid acetylation GO:0006473 28 16 1,000 1,881E-03 0,02755605 ! negative regulation of immune response GO:0050777 28 16 1,000 1,881E-03 0,02738165 ! detection of biotic stimulus GO:0009595 19 16 1,000 1,881E-03 0,02720944 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,881E-03 0,02703938 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 1,000 1,881E-03 0,02687143 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 1,000 1,881E-03 0,02670556 ! negative regulation of transferase activity GO:0051348 105 61 2,000 1,952E-03 0,02753882 ! respiratory tube development GO:0030323 99 62 2,000 2,045E-03 0,02867947 ! organelle localization GO:0051640 96 62 2,000 2,045E-03 0,02850565 ! positive regulation of cell killing GO:0031343 24 17 1,000 2,126E-03 0,02945958 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 2,126E-03 0,02928317 ! inactivation of MAPK activity GO:0000188 27 17 1,000 2,126E-03 0,02910887 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 1,000 2,126E-03 0,02893663 GO:0002712|regulation of B cell mediated immunity, ! peptidyl-serine modification GO:0018209 27 17 1,000 2,126E-03 0,02876641 ! regulation of immunoglobulin production GO:0002637 25 17 1,000 2,126E-03 0,02859819 ! aromatic compound catabolic process GO:0019439 22 17 1,000 2,126E-03 0,02843192 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 2,000 2,141E-03 0,02846431 ! viral reproduction GO:0016032 92 63 2,000 2,141E-03 0,02830072 ! respiratory system development GO:0060541 100 64 2,000 2,24E-03 0,02943754 ! regulation of MAPKKK cascade GO:0043408 101 65 2,000 2,341E-03 0,0305979 ! positive regulation of DNA replication GO:0045740 29 18 1,000 2,386E-03 0,03100091 ! positive regulation of cytoskeleton organization GO:0051495 33 18 1,000 2,386E-03 0,03082675 ! somitogenesis GO:0001756 24 18 1,000 2,386E-03 0,03065453 ! detection of chemical stimulus GO:0009593 26 18 1,000 2,386E-03 0,03048423 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 1,000 2,386E-03 0,03031581 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 2,386E-03 0,03014924 ! regulation of immune effector process GO:0002697 101 66 2,000 2,446E-03 0,0307397 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 2,659E-03 0,03324264 GO:0010675|regulation of cellular carbohydrate metabolic process, ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 2,659E-03 0,03306295 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 2,659E-03 0,03288519 ! sex determination GO:0007530 29 19 1,000 2,659E-03 0,03270933 ! response to lipopolysaccharide GO:0032496 26 19 1,000 2,659E-03 0,03253535 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 2,659E-03 0,0323632 ! regulation of interleukin-6 production GO:0032675 22 19 1,000 2,659E-03 0,03219287 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 2,659E-03 0,03202432 ! aromatic amino acid family metabolic process GO:0009072 24 19 1,000 2,659E-03 0,03185753 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 1,000 2,659E-03 0,03169246 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 2,659E-03 0,0315291 ! protein amino acid O-linked glycosylation GO:0006493 29 20 1,000 2,947E-03 0,03476141 ! pallium development GO:0021543 38 20 1,000 2,947E-03 0,03458406 ! positive regulation of inflammatory response GO:0050729 30 20 1,000 2,947E-03 0,0344085 ! positive regulation of B cell activation GO:0050871 31 20 1,000 2,947E-03 0,03423472 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 1,000 2,947E-03 0,03406269 ! regulation of peptidase activity GO:0052547 106 72 2,000 3,133E-03 0,03602761 ! regulation of cell killing GO:0031341 34 21 1,000 3,249E-03 0,03717605 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 3,249E-03 0,03699201 ! protein amino acid acylation GO:0043543 37 21 1,000 3,249E-03 0,03680978 ! vesicle docking GO:0048278 27 21 1,000 3,249E-03 0,03662934 ! regulation of DNA recombination GO:0000018 40 21 1,000 3,249E-03 0,03645066 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 1,000 3,249E-03 0,03627372 ! regulation of vasoconstriction GO:0019229 31 21 1,000 3,249E-03 0,03609848 ! immunoglobulin production GO:0002377 33 21 1,000 3,249E-03 0,03592493 GO:0002440|production of molecular mediator of immune response, ! positive regulation of adaptive immune response GO:0002821 31 21 1,000 3,249E-03 0,03575304 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 3,249E-03 0,03558279 ! negative regulation of cytokine production GO:0001818 31 21 1,000 3,249E-03 0,03541415 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 3,386E-03 0,03672968 ! viral genome replication GO:0019079 29 22 1,000 3,564E-03 0,03848879 ! leukocyte adhesion GO:0007159 38 22 1,000 3,564E-03 0,03830894 ! vasculogenesis GO:0001570 33 22 1,000 3,564E-03 0,03813076 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 1,000 3,564E-03 0,03795422 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 1,000 3,564E-03 0,03777932 ! regulation of tumor necrosis factor production GO:0032680 28 22 1,000 3,564E-03 0,03760602 ! membrane depolarization GO:0051899 35 22 1,000 3,564E-03 0,0374343 ! regulation of blood coagulation GO:0030193 34 22 1,000 3,564E-03 0,03726415 ! protein tetramerization GO:0051262 39 22 1,000 3,564E-03 0,03709553 ! regulation of DNA binding GO:0051101 119 77 2,000 3,787E-03 0,03923865 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 3,894E-03 0,04015871 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 3,894E-03 0,03997943 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 3,894E-03 0,03980175 ! interaction with host GO:0051701 37 23 1,000 3,894E-03 0,03962563 ! lymphocyte proliferation GO:0046651 36 23 1,000 3,894E-03 0,03945107 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 3,894E-03 0,03927804 ! T cell activation GO:0042110 134 79 2,000 4,071E-03 0,04088555 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 4,237E-03 0,04236507 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 4,237E-03 0,04218167 ! negative regulation of cell development GO:0010721 56 24 1,000 4,237E-03 0,04199986 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 4,237E-03 0,0418196 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 1,000 4,237E-03 0,04164088 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 4,237E-03 0,04146369 ! positive regulation of cell activation GO:0050867 120 81 2,000 4,367E-03 0,04255741 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 4,593E-03 0,04457204 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 4,593E-03 0,04438476 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 4,593E-03 0,04419905 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 4,593E-03 0,04401489 ! leukocyte proliferation GO:0070661 39 25 1,000 4,593E-03 0,04383226 GO:0032943|mononuclear cell proliferation, ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 4,963E-03 0,04716511 ! negative regulation of protein modification process GO:0031400 50 26 1,000 4,963E-03 0,04697102 ! positive regulation of innate immune response GO:0045089 31 26 1,000 4,963E-03 0,04677851 ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 4,963E-03 0,04658758 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 4,963E-03 0,0463982 ! regulation of coagulation GO:0050818 39 26 1,000 4,963E-03 0,04621035 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 4,997E-03 0,04634433 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 4,997E-03 0,04615821 ! skeletal muscle tissue development GO:0007519 123 87 2,000 5,332E-03 0,04905275 GO:0060538|skeletal muscle organ development, ! membrane docking GO:0022406 39 27 1,000 5,346E-03 0,0489835 ! acute-phase response GO:0006953 42 27 1,000 5,346E-03 0,04878912 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 1,000 5,346E-03 0,04859628 ! cholesterol homeostasis GO:0042632 46 28 1,000 5,742E-03 0,05199223 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 34 28 1,000 5,742E-03 0,05178834 ! immune response-activating signal transduction GO:0002757 38 28 1,000 5,742E-03 0,05158604 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 1,000 5,742E-03 0,05138532 ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 5,742E-03 0,05118615 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 5,742E-03 0,05098852 ! myeloid leukocyte activation GO:0002274 39 28 1,000 5,742E-03 0,05079241 ! positive regulation of catabolic process GO:0009896 40 28 1,000 5,742E-03 0,0505978 ! regulation of B cell activation GO:0050864 42 28 1,000 5,742E-03 0,05040468 ! regulation of innate immune response GO:0045088 38 29 1,000 6,151E-03 0,05379165 ! positive regulation of T cell proliferation GO:0042102 44 29 1,000 6,151E-03 0,0535879 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 6,151E-03 0,05338568 ! telencephalon development GO:0021537 52 29 1,000 6,151E-03 0,05318498 ! positive regulation of immune response GO:0050778 121 92 2,000 6,227E-03 0,05363738 ! cholesterol transport GO:0030301 46 30 1,000 6,573E-03 0,05641098 GO:0015918|sterol transport, ! regulation of microtubule-based process GO:0032886 58 30 1,000 6,573E-03 0,05620128 ! regulation of binding GO:0051098 151 95 2,000 6,804E-03 0,05795948 ! regulation of response to external stimulus GO:0032101 139 96 2,000 7,003E-03 0,05943696 ! mammary gland development GO:0030879 57 31 1,000 7,008E-03 0,05925953 ! segmentation GO:0035282 41 31 1,000 7,008E-03 0,05904246 ! cell fate specification GO:0001708 37 31 1,000 7,008E-03 0,05882697 ! neutral lipid metabolic process GO:0006638 41 32 1,000 7,456E-03 0,06235745 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 50 32 1,000 7,456E-03 0,06213152 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 7,456E-03 0,06190722 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 7,456E-03 0,06168453 ! calcium ion transport GO:0006816 167 99 2,000 7,622E-03 0,06283205 ! divalent metal ion transport GO:0070838 171 100 2,000 7,835E-03 0,06435849 ! carbohydrate homeostasis GO:0033500 39 33 1,000 7,916E-03 0,06479367 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 55 33 1,000 7,916E-03 0,0645639 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 1,000 7,916E-03 0,06433576 ! glycerol ether metabolic process GO:0006662 44 34 1,000 8,389E-03 0,06793842 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 8,874E-03 0,07161587 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 8,874E-03 0,07136547 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 9,372E-03 0,07510389 GO:0090047|positive regulation of transcription regulator activity, ! organic ether metabolic process GO:0018904 46 36 1,000 9,372E-03 0,07484311 ! tissue remodeling GO:0048771 62 36 1,000 9,372E-03 0,07458414 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,01040317 0,08250786 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,01093694 0,0864432 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 1,000 0,01093694 0,08614717 ! chromatin remodeling GO:0006338 68 39 1,000 0,01093694 0,08585315 ! cell growth GO:0016049 61 39 1,000 0,01093694 0,08556113 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 0,0114826 0,08952538 ! T cell differentiation GO:0030217 65 40 1,000 0,0114826 0,08922293 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,0114826 0,08892252 ! regulation of leukocyte mediated immunity GO:0002703 62 41 1,000 0,01204004 0,09292648 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,01204004 0,09261569 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,01260915 0,09667016 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,01260915 0,09634899 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,01318984 0,1004524 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 0,01318984 0,10012087 ! vesicle organization GO:0016050 79 43 1,000 0,01318984 0,09979153 ! regulation of inflammatory response GO:0050727 60 44 1,000 0,013782 0,10392981 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,013782 0,10359017 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,01438553 0,10777432 ! positive regulation of defense response GO:0031349 59 45 1,000 0,01438553 0,10742441 ! histone modification GO:0016570 68 46 1,000 0,01500034 0,11165299 ! regulation of adaptive immune response GO:0002819 72 46 1,000 0,01500034 0,11129282 ! response to UV GO:0009411 75 46 1,000 0,01500034 0,11093496 ! viral infectious cycle GO:0019058 71 47 1,000 0,01562632 0,11519402 ! covalent chromatin modification GO:0016569 75 47 1,000 0,01562632 0,11482598 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,01562632 0,1144603 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 0,01562632 0,11409693 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 1,000 0,01562632 0,11373586 ! regulation of muscle contraction GO:0006937 69 48 1,000 0,01626338 0,11799927 ! heart morphogenesis GO:0003007 65 48 1,000 0,01626338 0,11762821 ! regulation of DNA replication GO:0006275 75 48 1,000 0,01626338 0,11725947 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,01626338 0,11689303 ! positive regulation of cytokine production GO:0001819 73 48 1,000 0,01626338 0,11652888 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,01691142 0,12079584 ! membrane fusion GO:0006944 80 50 1,000 0,01757034 0,12511386 ! lipid modification GO:0030258 73 50 1,000 0,01757034 0,12472771 ! positive regulation of growth GO:0045927 67 50 1,000 0,01757034 0,12434393 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,01824005 0,12868744 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,01824005 0,1282939 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,01892044 0,13267384 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02014461 0,1408286 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02014461 0,14040184 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02014461 0,13997767 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02014461 0,13955605 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02014461 0,13913696 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02014461 0,13872038 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02014461 0,13830629 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02014461 0,13789467 ! sleep GO:0030431 11 5 0,000 0,02014461 0,13748549 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02014461 0,13707872 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02014461 0,13667436 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02014461 0,13627238 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02014461 0,13587275 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02014461 0,13547546 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02014461 0,13508049 ! tongue development GO:0043586 6 5 0,000 0,02014461 0,13468782 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02014461 0,13429742 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02014461 0,13390927 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02014461 0,13352337 ! cobalt ion transport GO:0006824 9 5 0,000 0,02014461 0,13313968 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02014461 0,13275819 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02014461 0,13237888 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02014461 0,13200173 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02014461 0,13162673 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02014461 0,13125385 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02014461 0,13088307 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02014461 0,13051439 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02014461 0,13014778 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02014461 0,12978322 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02014461 0,12942069 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02014461 0,12906019 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02014461 0,12870169 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,02014461 0,12834518 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02014461 0,12799063 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02014461 0,12763804 ! malate metabolic process GO:0006108 7 5 0,000 0,02014461 0,12728739 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02014461 0,12693865 ! behavioral response to pain GO:0048266 7 5 0,000 0,02014461 0,12659183 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02014461 0,12624689 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02014461 0,12590383 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02014461 0,12556262 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02014461 0,12522327 ! mating behavior GO:0007617 6 5 0,000 0,02014461 0,12488574 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02014461 0,12455002 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02014461 0,12421611 ! rhythmic behavior GO:0007622 12 5 0,000 0,02014461 0,12388398 ! copulation GO:0007620 7 5 0,000 0,02014461 0,12355362 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02014461 0,12322502 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02014461 0,12289817 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02014461 0,12257304 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02014461 0,12224963 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02014461 0,12192792 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02014461 0,1216079 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02014461 0,12128955 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02014461 0,12097287 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02014461 0,12065783 ! response to protozoan GO:0001562 9 5 0,000 0,02014461 0,12034444 ! lymph vessel development GO:0001945 7 5 0,000 0,02014461 0,12003266 ! endochondral ossification GO:0001958 12 5 0,000 0,02014461 0,1197225 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02014461 0,11941394 ! parathyroid gland development GO:0060017 8 5 0,000 0,02014461 0,11910696 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02014461 0,11880156 ! anagen GO:0042640 6 5 0,000 0,02014461 0,11849772 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02014461 0,11819543 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02014461 0,11789468 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02014461 0,11759545 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02014461 0,11729774 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02014461 0,11700154 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02014461 0,11670682 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02014461 0,11641359 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02014461 0,11612183 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02014461 0,11583152 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02014461 0,11554266 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02014461 0,11525525 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,02014461 0,11496925 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02014461 0,11468467 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02014461 0,1144015 ! ovulation GO:0030728 6 5 0,000 0,02014461 0,11411973 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02014461 0,11383933 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02014461 0,11356032 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,02014461 0,11328266 ! response to pH GO:0009268 9 5 0,000 0,02014461 0,11300636 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02014461 0,11273141 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02014461 0,11245779 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02014461 0,11218549 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02014461 0,11191451 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02014461 0,11164484 ! polyol catabolic process GO:0046174 7 5 0,000 0,02014461 0,11137646 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02014461 0,11110937 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02014461 0,11084356 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02014461 0,11057902 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02014461 0,11031573 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02014461 0,1100537 ! urea metabolic process GO:0019627 6 5 0,000 0,02014461 0,10979291 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02014461 0,10953335 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02014461 0,10927502 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02014461 0,1090179 ! neutrophil activation GO:0042119 5 5 0,000 0,02014461 0,10876199 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02014461 0,10850728 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02014461 0,10825376 ! response to food GO:0032094 5 5 0,000 0,02014461 0,10800142 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02014461 0,10775025 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02014461 0,10750025 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02014461 0,10725141 ! forebrain neuron development GO:0021884 7 5 0,000 0,02014461 0,10700371 ! melanosome organization GO:0032438 7 5 0,000 0,02014461 0,10675716 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02014461 0,10651174 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02014461 0,10626745 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02014461 0,10602428 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02014461 0,10578221 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02014461 0,10554125 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02014461 0,10530138 ! nucleoside transport GO:0015858 6 5 0,000 0,02014461 0,1050626 ! nucleoside salvage GO:0043174 7 5 0,000 0,02014461 0,10482491 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02014461 0,10458828 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02014461 0,10435272 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02014461 0,10411822 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02014461 0,10388477 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02014461 0,10365237 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02014461 0,103421 ! depyrimidination GO:0045008 8 5 0,000 0,02014461 0,10319066 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02014461 0,10296135 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02014461 0,10273306 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02014461 0,10250577 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02014461 0,10227949 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02014461 0,1020542 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02014461 0,10182991 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02014461 0,1016066 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02014461 0,10138426 ! monocyte differentiation GO:0030224 8 5 0,000 0,02014461 0,1011629 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02014461 0,1009425 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02014461 0,10072306 ! centrosome duplication GO:0051298 5 5 0,000 0,02014461 0,10050457 ! response to UV-C GO:0010225 6 5 0,000 0,02014461 0,10028703 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02014461 0,10007043 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02014461 0,09985476 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02014461 0,09964002 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02014461 0,0994262 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02014461 0,09921329 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02014461 0,0990013 ! melanosome transport GO:0032402 8 5 0,000 0,02014461 0,09879021 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02014461 0,09858002 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02014461 0,09837072 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02014461 0,09816231 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02014461 0,09795477 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02014461 0,09774812 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02014461 0,09754233 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02014461 0,09733741 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02014461 0,09713335 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02014461 0,09693014 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02014461 0,09672778 ! neural tube patterning GO:0021532 6 5 0,000 0,02014461 0,09652627 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02014461 0,09632559 ! histone demethylation GO:0016577 9 5 0,000 0,02014461 0,09612574 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02014461 0,09592673 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02014461 0,09572853 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02014461 0,09553115 ! enteric nervous system development GO:0048484 8 5 0,000 0,02014461 0,09533459 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02014461 0,09513883 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02014461 0,09494387 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02014461 0,09474971 ! transcription termination GO:0006353 8 5 0,000 0,02014461 0,09455634 ! plasminogen activation GO:0031639 5 5 0,000 0,02014461 0,09436376 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02014461 0,09417197 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02014461 0,09398095 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02014461 0,09379071 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02014461 0,09360123 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02014461 0,09341252 ! apical protein localization GO:0045176 6 5 0,000 0,02014461 0,09322456 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02014461 0,09303737 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02014461 0,09285092 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02014461 0,09266522 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02014461 0,09248026 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02014461 0,09229603 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02014461 0,09211254 ! glial cell migration GO:0008347 10 5 0,000 0,02014461 0,09192978 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02014461 0,09174774 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02014461 0,09156642 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02014461 0,09138582 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02014461 0,09120592 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02014461 0,09102674 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02014461 0,09084825 ! neural plate development GO:0001840 6 5 0,000 0,02014461 0,09067047 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,02014461 0,09049338 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02014461 0,09031698 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02014461 0,09014126 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02014461 0,08996623 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02014461 0,08979188 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02014461 0,0896182 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02014461 0,08944519 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02014461 0,08927285 ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02014461 0,08910117 ! spindle assembly GO:0051225 5 5 0,000 0,02014461 0,08893015 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02014461 0,08875979 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02014461 0,08859007 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02014461 0,08842101 ! organ regeneration GO:0031100 7 5 0,000 0,02014461 0,08825259 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02014461 0,08808481 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02014461 0,08791766 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02014461 0,08775115 GO:0055081|anion homeostasis, ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,02031293 0,08831708 ! cellular amino acid catabolic process GO:0009063 74 54 1,000 0,02031293 0,08815044 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,02031293 0,08798443 ! negative regulation of response to stimulus GO:0048585 80 56 1,000 0,02174704 0,09401915 ! tRNA transcription GO:0009304 11 6 0,000 0,02412526 0,10410524 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02412526 0,10391028 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02412526 0,10371606 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02412526 0,10352256 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02412526 0,10332978 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02412526 0,10313772 ! regulation of helicase activity GO:0051095 11 6 0,000 0,02412526 0,10294637 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02412526 0,10275573 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02412526 0,10256579 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02412526 0,10237655 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02412526 0,10218801 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02412526 0,10200017 ! prostate gland development GO:0030850 9 6 0,000 0,02412526 0,10181301 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02412526 0,10162654 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02412526 0,10144075 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02412526 0,10125564 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02412526 0,10107121 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02412526 0,10088744 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02412526 0,10070434 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02412526 0,10052191 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02412526 0,10034013 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02412526 0,10015901 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02412526 0,09997854 ! neuron adhesion GO:0007158 9 6 0,000 0,02412526 0,09979873 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02412526 0,09961955 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02412526 0,09944103 ! signal peptide processing GO:0006465 8 6 0,000 0,02412526 0,09926313 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02412526 0,09908588 ! mRNA stabilization GO:0048255 15 6 0,000 0,02412526 0,09890925 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02412526 0,09873326 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02412526 0,09855789 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02412526 0,09838314 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02412526 0,09820901 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02412526 0,0980355 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02412526 0,0978626 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02412526 0,0976903 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02412526 0,09751862 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02412526 0,09734753 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02412526 0,09717704 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02412526 0,09700715 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02412526 0,09683786 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02412526 0,09666915 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02412526 0,09650103 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02412526 0,09633349 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02412526 0,09616654 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02412526 0,09600016 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02412526 0,09583436 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02412526 0,09566912 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02412526 0,09550446 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02412526 0,09534036 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02412526 0,09517683 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02412526 0,09501386 ! protein lipoylation GO:0009249 10 6 0,000 0,02412526 0,09485144 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02412526 0,09468958 ! pigment granule organization GO:0048753 11 6 0,000 0,02412526 0,09452827 ! drug transport GO:0015893 6 6 0,000 0,02412526 0,0943675 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02412526 0,09420729 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02412526 0,09404761 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02412526 0,09388848 ! histidine metabolic process GO:0006547 6 6 0,000 0,02412526 0,09372989 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02412526 0,09357182 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02412526 0,0934143 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02412526 0,0932573 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02412526 0,09310083 ! adenohypophysis development GO:0021984 10 6 0,000 0,02412526 0,09294488 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02412526 0,09278945 ! hyperosmotic response GO:0006972 8 6 0,000 0,02412526 0,09263454 ! microtubule nucleation GO:0007020 10 6 0,000 0,02412526 0,09248015 ! ER overload response GO:0006983 7 6 0,000 0,02412526 0,09232628 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02412526 0,09217291 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02412526 0,09202005 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02412526 0,0918677 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02412526 0,09171585 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02412526 0,09156451 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02412526 0,09141366 ! response to dietary excess GO:0002021 7 6 0,000 0,02412526 0,09126331 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02412526 0,09111345 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02412526 0,09096409 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02412526 0,09081521 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02412526 0,09066682 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02412526 0,09051891 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02412526 0,09037149 ! neuron apoptosis GO:0051402 8 6 0,000 0,02412526 0,09022454 ! organic alcohol transport GO:0015850 9 6 0,000 0,02412526 0,09007807 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02412526 0,08993208 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02412526 0,08978656 ! carnitine transport GO:0015879 8 6 0,000 0,02412526 0,08964151 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02412526 0,08949692 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02412526 0,08935281 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02412526 0,08920915 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02412526 0,08906596 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02412526 0,08892322 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02412526 0,08878095 ! parturition GO:0007567 12 6 0,000 0,02412526 0,08863912 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02412526 0,08849775 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02412526 0,08835683 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02412526 0,08821636 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02412526 0,08807634 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02412526 0,08793675 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02412526 0,08779761 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02412526 0,08765891 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02412526 0,08752065 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02412526 0,08738282 ! astrocyte development GO:0014002 14 6 0,000 0,02412526 0,08724543 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02412526 0,08710846 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02412526 0,08697193 ! interaction with symbiont GO:0051702 8 6 0,000 0,02412526 0,08683582 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02412526 0,08670014 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02412526 0,08656489 ! eating behavior GO:0042755 6 6 0,000 0,02412526 0,08643005 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02412526 0,08629563 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02412526 0,08616163 ! response to copper ion GO:0046688 9 6 0,000 0,02412526 0,08602805 ! DNA topological change GO:0006265 8 6 0,000 0,02412526 0,08589488 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02412526 0,08576212 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02412526 0,08562977 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02412526 0,08549783 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02412526 0,0853663 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02412526 0,08523516 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02412526 0,08510444 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02412526 0,08497411 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02412526 0,08484418 ! hair follicle maturation GO:0048820 7 6 0,000 0,02412526 0,08471464 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02412526 0,08458551 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02412526 0,08445676 ! Schwann cell development GO:0014044 14 6 0,000 0,02412526 0,08432841 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02412526 0,08420044 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02412526 0,08407287 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02412526 0,08394568 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02412526 0,08381887 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02412526 0,08369245 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02412526 0,0835664 ! histone ubiquitination GO:0016574 7 6 0,000 0,02412526 0,08344074 ! regulation of meiosis GO:0040020 10 6 0,000 0,02412526 0,08331545 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02412526 0,08319054 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02412526 0,08306601 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02412526 0,08294184 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02412526 0,08281805 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02412526 0,08269462 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02412526 0,08257157 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02412526 0,08244887 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02412526 0,08232655 ! receptor internalization GO:0031623 9 6 0,000 0,02412526 0,08220458 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02412526 0,08208298 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02412526 0,08196173 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02412526 0,08184084 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02412526 0,08172031 ! protein deubiquitination GO:0016579 8 6 0,000 0,02412526 0,08160014 GO:0070646|protein modification by small protein removal, ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02412526 0,08148031 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02412526 0,08136084 ! axonal fasciculation GO:0007413 9 6 0,000 0,02412526 0,08124172 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02412526 0,08112294 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02412526 0,08100451 ! midbrain development GO:0030901 6 6 0,000 0,02412526 0,08088643 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02412526 0,08076869 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02412526 0,0806513 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02412526 0,08053424 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02412526 0,08041752 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02412526 0,08030115 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02412526 0,0801851 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02412526 0,0800694 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02412526 0,07995402 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02412526 0,07983898 ! adult feeding behavior GO:0008343 6 6 0,000 0,02412526 0,07972427 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02412526 0,07960989 ! blastocyst growth GO:0001832 15 6 0,000 0,02412526 0,07949583 ! pigment granule transport GO:0051904 12 6 0,000 0,02412526 0,07938211 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02412526 0,0792687 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02412526 0,07915562 ! catecholamine transport GO:0051937 7 6 0,000 0,02412526 0,07904287 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02412526 0,07893043 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02412526 0,07881831 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02412526 0,07870651 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02412526 0,07859503 ! protein prenylation GO:0018342 10 6 0,000 0,02412526 0,07848386 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02412526 0,07837301 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,02412526 0,07826247 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02412526 0,07815224 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,02473715 0,08002173 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,02473715 0,07990934 ! amine catabolic process GO:0009310 90 62 1,000 0,0262917 0,08481192 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,02708352 0,08724384 GO:0090046|regulation of transcription regulator activity, ! regulation of lipase activity GO:0060191 109 63 1,000 0,02708352 0,08712182 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,02808996 0,09023311 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02808996 0,09010726 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02808996 0,08998176 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02808996 0,08985661 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02808996 0,08973181 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02808996 0,08960736 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02808996 0,08948325 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02808996 0,08935948 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02808996 0,08923605 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02808996 0,08911297 ! reproductive behavior GO:0019098 12 7 0,000 0,02808996 0,08899022 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02808996 0,08886782 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02808996 0,08874575 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02808996 0,08862401 ! oligopeptide transport GO:0006857 11 7 0,000 0,02808996 0,08850261 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02808996 0,08838154 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02808996 0,0882608 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,02808996 0,08814039 ! pericardium development GO:0060039 8 7 0,000 0,02808996 0,0880203 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02808996 0,08790055 ! fibril organization GO:0043206 13 7 0,000 0,02808996 0,08778112 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02808996 0,08766201 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02808996 0,08754323 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02808996 0,08742477 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02808996 0,08730663 ! lipoprotein transport GO:0042953 9 7 0,000 0,02808996 0,0871888 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02808996 0,0870713 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02808996 0,08695411 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02808996 0,08683724 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02808996 0,08672068 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02808996 0,08660443 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02808996 0,08648849 ! chemosensory behavior GO:0007635 9 7 0,000 0,02808996 0,08637287 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02808996 0,08625755 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,02808996 0,08614254 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02808996 0,08602783 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02808996 0,08591344 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02808996 0,08579934 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02808996 0,08568555 ! reflex GO:0060004 12 7 0,000 0,02808996 0,08557206 ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02808996 0,08545887 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02808996 0,08534598 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02808996 0,08523338 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02808996 0,08512108 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02808996 0,08500908 ! spinal cord patterning GO:0021511 7 7 0,000 0,02808996 0,08489738 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02808996 0,08478596 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02808996 0,08467484 ! adrenal gland development GO:0030325 17 7 0,000 0,02808996 0,08456401 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02808996 0,08445347 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02808996 0,08434322 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02808996 0,08423325 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02808996 0,08412357 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02808996 0,08401418 ! endosome organization GO:0007032 10 7 0,000 0,02808996 0,08390507 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02808996 0,08379624 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02808996 0,0836877 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02808996 0,08357944 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02808996 0,08347145 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02808996 0,08336375 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02808996 0,08325632 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02808996 0,08314917 ! galactose metabolic process GO:0006012 10 7 0,000 0,02808996 0,08304229 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02808996 0,08293569 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02808996 0,08282936 ! organ growth GO:0035265 11 7 0,000 0,02808996 0,08272331 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02808996 0,08261752 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,02808996 0,08251201 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02808996 0,08240676 ! retinol metabolic process GO:0042572 9 7 0,000 0,02808996 0,08230179 ! behavioral fear response GO:0001662 13 7 0,000 0,02808996 0,08219708 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02808996 0,08209263 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02808996 0,08198846 ! rRNA modification GO:0000154 12 7 0,000 0,02808996 0,08188454 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02808996 0,08178089 ! response to UV-B GO:0010224 11 7 0,000 0,02808996 0,0816775 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,02808996 0,08157437 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02808996 0,0814715 ! intermediate filament organization GO:0045109 11 7 0,000 0,02808996 0,0813689 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02808996 0,08126654 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02808996 0,08116445 ! fibrinolysis GO:0042730 9 7 0,000 0,02808996 0,08106261 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,02808996 0,08096103 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02808996 0,0808597 ! B cell lineage commitment GO:0002326 17 7 0,000 0,02808996 0,08075863 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02808996 0,08065781 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02808996 0,08055724 ! response to tropane GO:0014073 13 7 0,000 0,02808996 0,08045692 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02808996 0,08035684 ! melanosome localization GO:0032400 10 7 0,000 0,02808996 0,08025702 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02808996 0,08015745 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02808996 0,08005812 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02808996 0,07995904 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02808996 0,0798602 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02808996 0,07976161 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02808996 0,07966326 ! mast cell activation GO:0045576 9 7 0,000 0,02808996 0,07956515 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02808996 0,07946729 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02808996 0,07936966 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02808996 0,07927227 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02808996 0,07917513 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,02808996 0,07907822 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02808996 0,07898154 ! T cell lineage commitment GO:0002360 12 7 0,000 0,02808996 0,07888511 ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02808996 0,07878891 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02808996 0,07869294 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02808996 0,07859721 ! response to tumor cell GO:0002347 12 7 0,000 0,02808996 0,07850171 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02808996 0,07840644 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02808996 0,0783114 ! diuresis GO:0030146 12 7 0,000 0,02808996 0,07821659 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02808996 0,07812201 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02808996 0,07802766 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02808996 0,07793354 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02808996 0,07783964 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02808996 0,07774597 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02808996 0,07765253 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02808996 0,07755931 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02808996 0,07746631 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02808996 0,07737354 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02808996 0,07728098 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02808996 0,07718865 ! lymph node development GO:0048535 9 7 0,000 0,02808996 0,07709654 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02808996 0,07700465 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,02808996 0,07691298 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02808996 0,07682153 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02808996 0,07673029 ! ATP catabolic process GO:0006200 10 7 0,000 0,02808996 0,07663927 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02808996 0,07654846 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02808996 0,07645787 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02808996 0,0763675 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02808996 0,07627734 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02808996 0,07618739 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02808996 0,07609765 ! muscle adaptation GO:0043500 12 7 0,000 0,02808996 0,07600812 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02808996 0,07591881 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02808996 0,0758297 ! retina homeostasis GO:0001895 9 7 0,000 0,02808996 0,0757408 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02808996 0,07565211 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,02808996 0,07556363 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02808996 0,07547535 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02808996 0,07538729 ! regulation of caspase activity GO:0043281 97 65 1,000 0,02869584 0,07692357 ! defense response to bacterium GO:0042742 73 65 1,000 0,02869584 0,07683402 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,02869584 0,07674468 ! activation of immune response GO:0002253 83 65 1,000 0,02869584 0,07665555 ! antigen processing and presentation GO:0019882 96 66 1,000 0,02951615 0,07875539 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 1,000 0,03034578 0,08087521 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,03034578 0,0807816 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,03034578 0,08068821 ! acute inflammatory response GO:0002526 92 68 1,000 0,03118465 0,08282298 ! cytosolic calcium ion homeostasis GO:0051480 107 68 1,000 0,03118465 0,08272745 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03203878 0,08489538 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03203878 0,08479768 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,03203878 0,08470022 ! axon extension GO:0048675 11 8 0,000 0,03203878 0,08460297 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,03203878 0,08450595 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03203878 0,08440915 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03203878 0,08431257 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03203878 0,08421621 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03203878 0,08412008 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03203878 0,08402416 ! phosphate transport GO:0006817 10 8 0,000 0,03203878 0,08392846 ! N-glycan processing GO:0006491 12 8 0,000 0,03203878 0,08383298 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03203878 0,08373771 ! UTP metabolic process GO:0046051 8 8 0,000 0,03203878 0,08364266 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03203878 0,08354783 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03203878 0,08345321 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,03203878 0,08335881 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03203878 0,08326462 ! succinate metabolic process GO:0006105 14 8 0,000 0,03203878 0,08317064 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,03203878 0,08307687 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03203878 0,08298332 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03203878 0,08288997 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,03203878 0,08279684 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,03203878 0,08270391 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,03203878 0,0826112 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03203878 0,08251869 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03203878 0,08242638 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03203878 0,08233429 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03203878 0,0822424 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03203878 0,08215071 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,03203878 0,08205923 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03203878 0,08196795 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03203878 0,08187687 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03203878 0,081786 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03203878 0,08169533 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,03203878 0,08160486 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03203878 0,08151459 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03203878 0,08142452 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03203878 0,08133464 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03203878 0,08124497 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03203878 0,08115549 ! melanin metabolic process GO:0006582 12 8 0,000 0,03203878 0,08106621 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03203878 0,08097713 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03203878 0,08088824 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,03203878 0,08079955 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03203878 0,08071105 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03203878 0,08062274 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03203878 0,08053463 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03203878 0,08044671 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03203878 0,08035898 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,03203878 0,08027145 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03203878 0,0801841 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03203878 0,08009694 ! ruffle organization GO:0031529 11 8 0,000 0,03203878 0,08000998 ! osteoblast development GO:0002076 13 8 0,000 0,03203878 0,0799232 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,03203878 0,07983661 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03203878 0,0797502 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03203878 0,07966399 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03203878 0,07957796 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,03203878 0,07949211 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03203878 0,07940645 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03203878 0,07932098 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03203878 0,07923569 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03203878 0,07915058 ! brain morphogenesis GO:0048854 20 8 0,000 0,03203878 0,07906565 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03203878 0,07898091 ! segment specification GO:0007379 10 8 0,000 0,03203878 0,07889635 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,03203878 0,07881196 ! cellular extravasation GO:0045123 11 8 0,000 0,03203878 0,07872776 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03203878 0,07864374 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,03203878 0,0785599 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03203878 0,07847624 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,03203878 0,07839275 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03203878 0,07830944 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03203878 0,07822631 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03203878 0,07814336 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03203878 0,07806058 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03203878 0,07797798 ! nucleosome disassembly GO:0006337 12 8 0,000 0,03203878 0,07789555 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03203878 0,07781329 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03203878 0,07773121 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03203878 0,0776493 ! icosanoid secretion GO:0032309 12 8 0,000 0,03203878 0,07756757 GO:0050482|arachidonic acid secretion, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03203878 0,077486 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03203878 0,07740461 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03203878 0,07732339 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03203878 0,07724233 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03203878 0,07716145 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,03203878 0,07708074 ! sterol catabolic process GO:0016127 9 8 0,000 0,03203878 0,0770002 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03203878 0,07691982 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03203878 0,07683961 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03203878 0,07675957 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03203878 0,0766797 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03203878 0,07659999 ! prophase GO:0051324 11 8 0,000 0,03203878 0,07652044 ! S phase GO:0051320 8 8 0,000 0,03203878 0,07644107 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03203878 0,07636185 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,03203878 0,0762828 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03203878 0,07620392 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03203878 0,07612519 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03203878 0,07604663 ! hormone catabolic process GO:0042447 13 8 0,000 0,03203878 0,07596823 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03203878 0,07589 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03203878 0,07581192 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03203878 0,07573401 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03203878 0,07565625 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03203878 0,07557865 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,03203878 0,07550122 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03203878 0,07542394 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03203878 0,07534682 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03203878 0,07526985 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03203878 0,07519305 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03203878 0,0751164 ! lamellipodium assembly GO:0030032 9 8 0,000 0,03203878 0,07503991 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03203878 0,07496357 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,03203878 0,07488739 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,03203878 0,07481136 ! response to metal ion GO:0010038 103 70 1,000 0,03288974 0,07672049 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,03288974 0,07664276 ! regulation of catabolic process GO:0009894 106 70 1,000 0,03288974 0,07656518 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,03375579 0,07850184 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,03463073 0,08045523 GO:0045937|positive regulation of phosphate metabolic process, ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,03551448 0,08242513 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03597178 0,08340231 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03597178 0,08331832 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03597178 0,08323449 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03597178 0,08315084 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03597178 0,08306736 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03597178 0,08298404 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03597178 0,08290089 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03597178 0,08281791 ! GTP metabolic process GO:0046039 9 9 0,000 0,03597178 0,08273509 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03597178 0,08265244 ! social behavior GO:0035176 14 9 0,000 0,03597178 0,08256995 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03597178 0,08248762 ! artery development GO:0060840 19 9 0,000 0,03597178 0,08240547 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03597178 0,08232347 ! response to pain GO:0048265 16 9 0,000 0,03597178 0,08224164 ! protein complex disassembly GO:0043241 17 9 0,000 0,03597178 0,08215997 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03597178 0,08207846 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03597178 0,08199711 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03597178 0,08191593 ! lung alveolus development GO:0048286 17 9 0,000 0,03597178 0,0818349 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03597178 0,08175404 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,03597178 0,08167333 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03597178 0,08159279 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03597178 0,0815124 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03597178 0,08143217 ! protein targeting to ER GO:0045047 19 9 0,000 0,03597178 0,0813521 ! endoderm development GO:0007492 12 9 0,000 0,03597178 0,08127219 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03597178 0,08119243 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03597178 0,08111283 ! arginine catabolic process GO:0006527 10 9 0,000 0,03597178 0,08103339 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03597178 0,0809541 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03597178 0,08087496 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03597178 0,08079598 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03597178 0,08071716 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,03597178 0,08063849 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03597178 0,08055997 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03597178 0,0804816 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03597178 0,08040339 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03597178 0,08032533 ! mannose metabolic process GO:0006013 9 9 0,000 0,03597178 0,08024742 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03597178 0,08016966 ! receptor clustering GO:0043113 15 9 0,000 0,03597178 0,08009205 ! epithelial cell development GO:0002064 10 9 0,000 0,03597178 0,08001459 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03597178 0,07993728 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03597178 0,07986012 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03597178 0,07978311 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03597178 0,07970625 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03597178 0,07962954 ! motor axon guidance GO:0008045 14 9 0,000 0,03597178 0,07955297 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03597178 0,07947655 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03597178 0,07940028 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03597178 0,07932415 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03597178 0,07924817 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03597178 0,07917233 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03597178 0,07909664 ! DNA ligation GO:0006266 14 9 0,000 0,03597178 0,0790211 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03597178 0,07894569 ! response to amine stimulus GO:0014075 13 9 0,000 0,03597178 0,07887044 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03597178 0,07879532 ! erythrocyte development GO:0048821 11 9 0,000 0,03597178 0,07872035 ! renal water homeostasis GO:0003091 14 9 0,000 0,03597178 0,07864552 ! postreplication repair GO:0006301 11 9 0,000 0,03597178 0,07857083 ! mRNA cleavage GO:0006379 13 9 0,000 0,03597178 0,07849629 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03597178 0,07842188 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03597178 0,07834762 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03597178 0,0782735 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03597178 0,07819952 ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03597178 0,07812567 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03597178 0,07805197 ! acid secretion GO:0046717 14 9 0,000 0,03597178 0,07797841 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03597178 0,07790498 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03597178 0,07783169 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03597178 0,07775854 ! purine base metabolic process GO:0006144 18 9 0,000 0,03597178 0,07768553 ! oocyte differentiation GO:0009994 12 9 0,000 0,03597178 0,07761265 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03597178 0,07753991 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03597178 0,07746731 ! spleen development GO:0048536 15 9 0,000 0,03597178 0,07739484 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03597178 0,07732251 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03597178 0,07725032 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03597178 0,07717825 ! detection of calcium ion GO:0005513 13 9 0,000 0,03597178 0,07710633 ! blastocyst formation GO:0001825 12 9 0,000 0,03597178 0,07703453 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03597178 0,07696287 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03597178 0,07689135 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03597178 0,07681995 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03597178 0,07674869 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03597178 0,07667756 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03597178 0,07660656 ! prepulse inhibition GO:0060134 14 9 0,000 0,03597178 0,0765357 ! embryonic placenta development GO:0001892 12 9 0,000 0,03597178 0,07646496 ! insulin secretion GO:0030073 17 9 0,000 0,03597178 0,07639436 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03597178 0,07632388 ! response to nicotine GO:0035094 16 9 0,000 0,03597178 0,07625354 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03597178 0,07618332 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03597178 0,07611324 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,03640695 0,07696322 ! blood coagulation GO:0007596 116 75 1,000 0,03730806 0,07879572 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 1,000 0,03730806 0,07872343 ! regulation of protein transport GO:0051223 114 76 1,000 0,03821773 0,080569 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 148 77 1,000 0,03913587 0,08242903 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03988902 0,08393847 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03988902 0,08386174 ! neuron fate specification GO:0048665 11 10 0,000 0,03988902 0,08378516 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03988902 0,08370871 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03988902 0,08363241 ! thyroid gland development GO:0030878 19 10 0,000 0,03988902 0,08355624 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03988902 0,08348021 ! synapsis GO:0007129 13 10 0,000 0,03988902 0,08340432 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03988902 0,08332856 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03988902 0,08325295 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03988902 0,08317747 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03988902 0,08310213 ! sulfate transport GO:0008272 12 10 0,000 0,03988902 0,08302692 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03988902 0,08295185 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,03988902 0,08287692 ! phospholipid efflux GO:0033700 16 10 0,000 0,03988902 0,08280212 ! blood vessel remodeling GO:0001974 21 10 0,000 0,03988902 0,08272746 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03988902 0,08265293 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03988902 0,08257853 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03988902 0,08250427 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03988902 0,08243014 ! pathogenesis GO:0009405 13 10 0,000 0,03988902 0,08235615 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03988902 0,08228229 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03988902 0,08220856 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03988902 0,08213496 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03988902 0,08206149 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,03988902 0,08198816 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03988902 0,08191495 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03988902 0,08184188 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03988902 0,08176894 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03988902 0,08169613 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03988902 0,08162344 ! response to X-ray GO:0010165 16 10 0,000 0,03988902 0,08155089 ! B cell proliferation GO:0042100 14 10 0,000 0,03988902 0,08147846 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03988902 0,08140617 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03988902 0,081334 ! forebrain cell migration GO:0021885 17 10 0,000 0,03988902 0,08126196 ! lipid digestion GO:0044241 15 10 0,000 0,03988902 0,08119004 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03988902 0,08111826 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03988902 0,0810466 ! UV protection GO:0009650 14 10 0,000 0,03988902 0,08097507 ! entry into host cell GO:0030260 20 10 0,000 0,03988902 0,08090366 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03988902 0,08083238 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03988902 0,08076122 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03988902 0,08069019 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03988902 0,08061929 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,03988902 0,08054851 ! regulation of bone resorption GO:0045124 24 10 0,000 0,03988902 0,08047785 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03988902 0,08040732 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03988902 0,08033691 ! regulation of organ growth GO:0046620 11 10 0,000 0,03988902 0,08026662 ! response to dsRNA GO:0043331 18 10 0,000 0,03988902 0,08019646 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03988902 0,08012642 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03988902 0,0800565 ! embryonic axis specification GO:0000578 12 10 0,000 0,03988902 0,0799867 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03988902 0,07991703 ! cranial nerve development GO:0021545 12 10 0,000 0,03988902 0,07984748 ! fucose catabolic process GO:0019317 16 10 0,000 0,03988902 0,07977804 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03988902 0,07970873 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03988902 0,07963954 ! protein sumoylation GO:0016925 12 10 0,000 0,03988902 0,07957047 ! zymogen activation GO:0031638 14 10 0,000 0,03988902 0,07950152 ! salivary gland development GO:0007431 22 10 0,000 0,03988902 0,07943268 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03988902 0,07936397 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03988902 0,07929537 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03988902 0,0792269 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,03988902 0,07915854 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03988902 0,0790903 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03988902 0,07902218 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03988902 0,07895417 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03988902 0,07888628 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03988902 0,07881851 ! detection of bacterium GO:0016045 10 10 0,000 0,03988902 0,07875086 ! embryonic gut development GO:0048566 11 10 0,000 0,03988902 0,07868332 ! activation of innate immune response GO:0002218 10 10 0,000 0,03988902 0,07861589 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03988902 0,07854859 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03988902 0,07848139 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,03988902 0,07841432 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03988902 0,07834735 ! nitrogen compound catabolic process GO:0044270 114 78 1,000 0,04006241 0,07862077 ! forebrain development GO:0030900 131 80 1,000 0,04194033 0,08223595 ! hemostasis GO:0007599 125 81 1,000 0,04289156 0,08402947 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,04289156 0,08395795 ! rRNA transcription GO:0009303 17 11 0,000 0,04379057 0,08564482 ! respiratory burst GO:0045730 14 11 0,000 0,04379057 0,08557206 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,04379057 0,08549942 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,04379057 0,0854269 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,04379057 0,0853545 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,04379057 0,08528223 GO:0000725|recombinational repair, ! Golgi vesicle budding GO:0048194 17 11 0,000 0,04379057 0,08521008 ! RNA polyadenylation GO:0043631 19 11 0,000 0,04379057 0,08513805 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,04379057 0,08506614 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,04379057 0,08499436 ! mating GO:0007618 14 11 0,000 0,04379057 0,08492269 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,04379057 0,08485115 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,04379057 0,08477973 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,04379057 0,08470842 ! bone resorption GO:0045453 16 11 0,000 0,04379057 0,08463724 ! regulated secretory pathway GO:0045055 14 11 0,000 0,04379057 0,08456617 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,04379057 0,08449523 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,04379057 0,0844244 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,04379057 0,0843537 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,04379057 0,08428311 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,04379057 0,08421264 ! syncytium formation GO:0006949 15 11 0,000 0,04379057 0,08414228 ! plasma membrane organization GO:0007009 18 11 0,000 0,04379057 0,08407205 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,04379057 0,08400193 ! focal adhesion formation GO:0048041 24 11 0,000 0,04379057 0,08393193 ! mitotic spindle organization GO:0007052 15 11 0,000 0,04379057 0,08386204 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,04379057 0,08379227 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,04379057 0,08372262 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,04379057 0,08365308 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,04379057 0,08358366 ! adult heart development GO:0007512 11 11 0,000 0,04379057 0,08351436 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,04379057 0,08344516 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,04379057 0,08337609 ! temperature homeostasis GO:0001659 16 11 0,000 0,04379057 0,08330712 ! L-glutamate transport GO:0015813 16 11 0,000 0,04379057 0,08323828 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,04379057 0,08316954 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,04379057 0,08310092 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,04379057 0,08303241 ! stem cell development GO:0048864 29 11 0,000 0,04379057 0,08296401 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,04379057 0,08289573 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,04379057 0,08282756 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,04379057 0,0827595 ! vasoconstriction GO:0042310 15 11 0,000 0,04379057 0,08269155 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,04379057 0,08262372 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,04379057 0,08255599 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,04379057 0,08248838 ! ribosome assembly GO:0042255 13 11 0,000 0,04379057 0,08242088 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,04379057 0,08235349 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,04379057 0,0822862 ! chromatin silencing GO:0006342 19 11 0,000 0,04379057 0,08221903 ! nucleosome positioning GO:0016584 13 11 0,000 0,04379057 0,08215197 ! T cell homeostasis GO:0043029 20 11 0,000 0,04379057 0,08208502 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,04379057 0,08201817 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,04379057 0,08195143 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,04379057 0,08188481 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,04379057 0,08181829 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,04379057 0,08175188 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,04379057 0,08168557 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,04379057 0,08161938 ! male genitalia development GO:0030539 13 11 0,000 0,04379057 0,08155329 ! cholesterol efflux GO:0033344 19 11 0,000 0,04379057 0,08148731 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,04379057 0,08142143 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,04379057 0,08135567 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,04379057 0,08129 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,04379057 0,08122445 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,04379057 0,081159 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,04379057 0,08109365 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,04379057 0,08102841 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,04379057 0,08096327 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,04379057 0,08089824 ! lysogeny GO:0030069 18 11 0,000 0,04379057 0,08083332 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,04379057 0,0807685 ! acrosome reaction GO:0007340 13 11 0,000 0,04379057 0,08070378 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,04379057 0,08063916 ! ossification GO:0001503 134 82 1,000 0,04385086 0,08068559 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 1,000 0,04385086 0,08062109 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,04481816 0,08233368 ! regulation of defense response GO:0031347 117 84 1,000 0,04579336 0,08405805 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,04677641 0,08579405 ! regulation of protein localization GO:0032880 132 85 1,000 0,04677641 0,08572568 ! regulation of membrane potential GO:0042391 128 85 1,000 0,04677641 0,08565743 ! lactation GO:0007595 20 12 0,000 0,04767649 0,08723622 ! reproductive cellular process GO:0048610 14 12 0,000 0,04767649 0,08716687 ! tRNA modification GO:0006400 14 12 0,000 0,04767649 0,08709764 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,04767649 0,08702851 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,04767649 0,0869595 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,04767649 0,08689059 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,04767649 0,08682179 ! non-recombinational repair GO:0000726 19 12 0,000 0,04767649 0,0867531 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,04767649 0,08668453 ! peroxisomal transport GO:0043574 21 12 0,000 0,04767649 0,08661605 ! cartilage condensation GO:0001502 18 12 0,000 0,04767649 0,08654769 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,04767649 0,08647944 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,04767649 0,08641129 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,04767649 0,08634325 ! heart looping GO:0001947 15 12 0,000 0,04767649 0,08627531 ! palate development GO:0060021 15 12 0,000 0,04767649 0,08620749 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,04767649 0,08613977 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,04767649 0,08607215 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,04767649 0,08600465 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,04767649 0,08593724 ! arginine metabolic process GO:0006525 13 12 0,000 0,04767649 0,08586995 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,04767649 0,08580276 ! methionine metabolic process GO:0006555 13 12 0,000 0,04767649 0,08573567 ! Golgi organization GO:0007030 18 12 0,000 0,04767649 0,08566869 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,04767649 0,08560181 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,04767649 0,08553504 ! monoamine transport GO:0015844 13 12 0,000 0,04767649 0,08546837 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04767649 0,08540181 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,04767649 0,08533535 ! L-amino acid transport GO:0015807 20 12 0,000 0,04767649 0,08526899 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,04767649 0,08520274 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,04767649 0,08513659 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,04767649 0,08507054 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04767649 0,08500459 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,04767649 0,08493875 ! cerebellum development GO:0021549 13 12 0,000 0,04767649 0,08487301 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,04767649 0,08480737 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,04767649 0,08474183 ! histone methylation GO:0016571 15 12 0,000 0,04767649 0,08467639 ! autonomic nervous system development GO:0048483 23 12 0,000 0,04767649 0,08461105 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,04767649 0,08454582 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,04767649 0,08448068 ! response to gamma radiation GO:0010332 20 12 0,000 0,04767649 0,08441565 ! regulation of epidermis development GO:0045682 17 12 0,000 0,04767649 0,08435071 ! intestinal absorption GO:0050892 19 12 0,000 0,04767649 0,08428588 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,04767649 0,08422114 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,04767649 0,0841565 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,04767649 0,08409197 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,04767649 0,08402753 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,04767649 0,08396319 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,04767649 0,08389895 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,04767649 0,0838348 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,04767649 0,08377076 ! response to cold GO:0009409 14 12 0,000 0,04767649 0,08370681 ! cellular defense response GO:0006968 102 87 1,000 0,04876569 0,08555383 ! carboxylic acid catabolic process GO:0046395 122 88 1,000 0,04977177 0,08725234 GO:0016054|organic acid catabolic process, ! regulation of neurogenesis GO:0050767 153 89 1,000 0,05078538 0,08896144 ! reproductive developmental process GO:0003006 127 89 1,000 0,05078538 0,08889374 ! regulation of T cell activation GO:0050863 128 89 1,000 0,05078538 0,08882614 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,05154684 0,09008946 ! cGMP metabolic process GO:0046068 16 13 0,000 0,05154684 0,09002105 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,05154684 0,08995275 ! water transport GO:0006833 17 13 0,000 0,05154684 0,08988455 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,05154684 0,08981646 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,05154684 0,08974847 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,05154684 0,08968058 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,05154684 0,08961279 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,05154684 0,08954511 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,05154684 0,08947753 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,05154684 0,08941005 ! response to hexose stimulus GO:0009746 19 13 0,000 0,05154684 0,08934267 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,05154684 0,08927539 ! glutamate metabolic process GO:0006536 18 13 0,000 0,05154684 0,08920822 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,05154684 0,08914115 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,05154684 0,08907417 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,05154684 0,0890073 ! NAD metabolic process GO:0019674 21 13 0,000 0,05154684 0,08894053 ! exocrine system development GO:0035272 27 13 0,000 0,05154684 0,08887386 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,05154684 0,08880728 ! bone mineralization GO:0030282 15 13 0,000 0,05154684 0,08874081 ! regulation of exocytosis GO:0017157 17 13 0,000 0,05154684 0,08867444 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,05154684 0,08860816 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,05154684 0,08854199 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,05154684 0,08847591 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,05154684 0,08840994 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,05154684 0,08834406 ! genitalia development GO:0048806 15 13 0,000 0,05154684 0,08827828 ! regulation of cellular pH GO:0030641 20 13 0,000 0,05154684 0,08821259 ! cellular pigmentation GO:0033059 24 13 0,000 0,05154684 0,08814701 ! tissue regeneration GO:0042246 21 13 0,000 0,05154684 0,08808152 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,05154684 0,08801613 ! cofactor transport GO:0051181 19 13 0,000 0,05154684 0,08795083 ! NADP metabolic process GO:0006739 18 13 0,000 0,05154684 0,08788564 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,05154684 0,08782054 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05154684 0,08775553 ! gas transport GO:0015669 18 13 0,000 0,05154684 0,08769062 ! regulation of RNA stability GO:0043487 28 13 0,000 0,05154684 0,08762581 ! heme biosynthetic process GO:0006783 20 13 0,000 0,05154684 0,0875611 ! regulation of axon extension GO:0030516 23 13 0,000 0,05154684 0,08749647 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,05154684 0,08743195 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,05154684 0,08736752 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,05154684 0,08730318 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,05154684 0,08723894 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,05154684 0,0871748 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,05154684 0,08711074 ! response to virus GO:0009615 122 91 1,000 0,05283488 0,0892219 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,05387062 0,0909042 ! cell fate commitment GO:0045165 141 92 1,000 0,05387062 0,09083755 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,05491358 0,09252838 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,05540167 0,09328247 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,05540167 0,09321423 ! superoxide anion generation GO:0042554 18 14 0,000 0,05540167 0,09314609 ! neuron maturation GO:0042551 21 14 0,000 0,05540167 0,09307805 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,05540167 0,09301011 ! myotube differentiation GO:0014902 21 14 0,000 0,05540167 0,09294227 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,05540167 0,09287453 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,05540167 0,09280688 ! inositol metabolic process GO:0006020 20 14 0,000 0,05540167 0,09273934 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,05540167 0,09267189 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,05540167 0,09260454 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,05540167 0,09253729 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,05540167 0,09247014 ! gene silencing by RNA GO:0031047 20 14 0,000 0,05540167 0,09240308 ! response to cAMP GO:0051591 19 14 0,000 0,05540167 0,09233612 ! startle response GO:0001964 21 14 0,000 0,05540167 0,09226926 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,05540167 0,0922025 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,05540167 0,09213583 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,05540167 0,09206926 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,05540167 0,09200278 ! glycine metabolic process GO:0006544 22 14 0,000 0,05540167 0,0919364 ! pituitary gland development GO:0021983 23 14 0,000 0,05540167 0,09187012 ! cellular response to starvation GO:0009267 21 14 0,000 0,05540167 0,09180393 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,05540167 0,09173783 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,05540167 0,09167184 ! regulation of heart rate GO:0002027 23 14 0,000 0,05540167 0,09160593 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,05540167 0,09154012 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,05540167 0,09147441 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,05540167 0,09140879 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,05540167 0,09134326 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,05540167 0,09127783 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,05540167 0,09121249 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,05540167 0,09114725 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,05540167 0,0910821 ! axon cargo transport GO:0008088 27 14 0,000 0,05540167 0,09101704 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,05540167 0,09095207 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,05540167 0,0908872 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,05540167 0,09082242 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05540167 0,09075773 ! mRNA splice site selection GO:0006376 26 14 0,000 0,05540167 0,09069313 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,05540167 0,09062863 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,05540167 0,09056422 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,05540167 0,0904999 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,05540167 0,09043567 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,05540167 0,09037153 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,05540167 0,09030748 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,05540167 0,09024352 ! muscle maintenance GO:0046716 19 14 0,000 0,05540167 0,09017965 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,05540167 0,09011588 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,05540167 0,09005219 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,05540167 0,0899886 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,05540167 0,08992509 ! cell killing GO:0001906 20 14 0,000 0,05540167 0,08986167 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,05540167 0,08979835 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,05540167 0,08973511 ! cilium assembly GO:0042384 20 14 0,000 0,05540167 0,08967196 ! peptide hormone secretion GO:0030072 23 14 0,000 0,05540167 0,0896089 ! response to oxidative stress GO:0006979 141 94 1,000 0,0559637 0,09045434 ! response to light stimulus GO:0009416 153 96 1,000 0,05808511 0,09381724 ! protein amino acid glycosylation GO:0006486 134 97 1,000 0,05915625 0,09548026 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,05924107 0,09555011 ! positive regulation of cell size GO:0045793 20 15 0,000 0,05924107 0,09548315 ! metencephalon development GO:0022037 19 15 0,000 0,05924107 0,09541628 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05924107 0,09534951 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,05924107 0,09528283 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,05924107 0,09521625 ! skin development GO:0043588 25 15 0,000 0,05924107 0,09514976 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,05924107 0,09508336 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,05924107 0,09501705 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,05924107 0,09495084 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05924107 0,09488472 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05924107 0,09481869 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05924107 0,09475275 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,05924107 0,0946869 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05924107 0,09462115 ! adult walking behavior GO:0007628 25 15 0,000 0,05924107 0,09455548 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05924107 0,09448991 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,05924107 0,09442443 ! myoblast differentiation GO:0045445 27 15 0,000 0,05924107 0,09435904 ! centrosome cycle GO:0007098 16 15 0,000 0,05924107 0,09429374 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05924107 0,09422853 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,05924107 0,09416341 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,05924107 0,09409838 ! cerebral cortex development GO:0021987 29 15 0,000 0,05924107 0,09403344 ! response to osmotic stress GO:0006970 22 15 0,000 0,05924107 0,09396859 ! vesicle coating GO:0006901 25 15 0,000 0,05924107 0,09390383 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,05924107 0,09383915 ! DNA integration GO:0015074 22 15 0,000 0,05924107 0,09377457 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,05924107 0,09371008 ! peptide secretion GO:0002790 27 15 0,000 0,05924107 0,09364567 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05924107 0,09358135 ! neuron recognition GO:0008038 22 15 0,000 0,05924107 0,09351713 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,05924107 0,09345298 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05924107 0,09338893 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,05924107 0,09332497 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,05924107 0,09326109 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05924107 0,0931973 ! biomineral formation GO:0031214 18 15 0,000 0,05924107 0,0931336 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05924107 0,09306998 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,05924107 0,09300645 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05924107 0,09294301 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05924107 0,09287965 ! organic cation transport GO:0015695 19 15 0,000 0,05924107 0,09281638 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05924107 0,0927532 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05924107 0,0926901 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,05924107 0,09262709 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,05924107 0,09256417 ! peptide hormone processing GO:0016486 19 15 0,000 0,05924107 0,09250132 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,05924107 0,09243857 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,06131904 0,09561614 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,06241056 0,09725222 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,06241056 0,09718638 ! protein secretion GO:0009306 27 16 0,000 0,06306507 0,09813915 ! hormone secretion GO:0046879 25 16 0,000 0,06306507 0,09807279 ! bone remodeling GO:0046849 24 16 0,000 0,06306507 0,09800653 ! endothelial cell migration GO:0043542 22 16 0,000 0,06306507 0,09794035 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,06306507 0,09787427 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06306507 0,09780827 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,06306507 0,09774236 ! glial cell development GO:0021782 24 16 0,000 0,06306507 0,09767654 ! patterning of blood vessels GO:0001569 24 16 0,000 0,06306507 0,09761081 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,06306507 0,09754517 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,06306507 0,09747961 ! protein polyubiquitination GO:0000209 26 16 0,000 0,06306507 0,09741414 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,06306507 0,09734877 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,06306507 0,09728348 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,06306507 0,09721827 ! fructose metabolic process GO:0006000 20 16 0,000 0,06306507 0,09715316 ! regulation of protein binding GO:0043393 27 16 0,000 0,06306507 0,09708813 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,06306507 0,09702318 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,06306507 0,09695833 ! protein export from nucleus GO:0006611 24 16 0,000 0,06306507 0,09689356 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,06306507 0,09682888 ! DNA replication initiation GO:0006270 25 16 0,000 0,06306507 0,09676428 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,06306507 0,09669977 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,06306507 0,09663535 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,06306507 0,09657101 ! diencephalon development GO:0021536 25 16 0,000 0,06306507 0,09650676 ! oogenesis GO:0048477 23 16 0,000 0,06306507 0,09644259 ! neural crest cell migration GO:0001755 24 16 0,000 0,06306507 0,09637851 ! G1 phase GO:0051318 27 16 0,000 0,06306507 0,09631452 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,06306507 0,0962506 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,06306507 0,09618678 GO:0006626|protein targeting to mitochondrion, ! steroid catabolic process GO:0006706 22 16 0,000 0,06306507 0,09612304 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,06306507 0,09605938 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,06306507 0,09599581 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,06306507 0,09593232 ! sperm-egg recognition GO:0035036 16 16 0,000 0,06306507 0,09586891 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,06306507 0,09580559 ! nerve development GO:0021675 18 16 0,000 0,06306507 0,09574235 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,06306507 0,0956792 ! negative regulation of translation GO:0017148 22 16 0,000 0,06306507 0,09561612 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,06687375 0,10132386 ! negative regulation of defense response GO:0031348 19 17 0,000 0,06687375 0,10125716 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,06687375 0,10119054 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,06687375 0,10112401 ! glycerol metabolic process GO:0006071 20 17 0,000 0,06687375 0,10105757 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,06687375 0,10099122 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,06687375 0,10092495 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,06687375 0,10085877 ! signal complex assembly GO:0007172 29 17 0,000 0,06687375 0,10079268 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,06687375 0,10072667 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,06687375 0,10066075 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,06687375 0,10059491 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,06687375 0,10052916 ! memory GO:0007613 25 17 0,000 0,06687375 0,1004635 ! keratinization GO:0031424 17 17 0,000 0,06687375 0,10039793 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,06687375 0,10033243 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,06687375 0,10026703 ! retinoid metabolic process GO:0001523 22 17 0,000 0,06687375 0,10020171 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,06687375 0,10013647 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,06687375 0,10007132 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,06687375 0,10000626 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,06687375 0,09994127 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,06687375 0,09987638 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,06687375 0,09981157 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,06687375 0,09974684 ! membrane budding GO:0006900 29 17 0,000 0,06687375 0,09968219 ! heme metabolic process GO:0042168 27 17 0,000 0,06687375 0,09961763 ! actin filament bundle formation GO:0051017 26 17 0,000 0,06687375 0,09955315 ! neuromuscular junction development GO:0007528 23 17 0,000 0,06687375 0,09948876 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,06687375 0,09942445 ! body fluid secretion GO:0007589 27 17 0,000 0,06687375 0,09936022 ! stem cell differentiation GO:0048863 36 17 0,000 0,06687375 0,09929608 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,06687375 0,09923201 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,06687375 0,09916803 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,06687375 0,09910414 ! sensory perception of pain GO:0019233 23 17 0,000 0,06687375 0,09904032 ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,06687375 0,09897659 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,06687375 0,09891294 ! synaptogenesis GO:0007416 24 17 0,000 0,06687375 0,09884937 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,06687375 0,09878588 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,06687375 0,09872248 ! cell-cell junction organization GO:0045216 25 17 0,000 0,06687375 0,09865915 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,06687375 0,09859591 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,06687375 0,09853275 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,06687375 0,09846967 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,06687375 0,09840667 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,07066716 0,1039223 ! positive regulation of translation GO:0045727 28 18 0,000 0,07066716 0,10385589 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,07066716 0,10378957 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,07066716 0,10372334 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,07066716 0,10365719 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,07066716 0,10359112 ! cAMP metabolic process GO:0046058 33 18 0,000 0,07066716 0,10352514 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,07066716 0,10345924 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,07066716 0,10339343 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,07066716 0,1033277 ! axis specification GO:0009798 26 18 0,000 0,07066716 0,10326205 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,07066716 0,10319649 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,07066716 0,10313101 ! pancreas development GO:0031016 26 18 0,000 0,07066716 0,10306561 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,07066716 0,1030003 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,07066716 0,10293507 ! glutamine metabolic process GO:0006541 23 18 0,000 0,07066716 0,10286992 ! response to retinoic acid GO:0032526 25 18 0,000 0,07066716 0,10280485 ! pigmentation during development GO:0048066 31 18 0,000 0,07066716 0,10273987 ! central nervous system neuron development GO:0021954 30 18 0,000 0,07066716 0,10267497 ! fucose metabolic process GO:0006004 26 18 0,000 0,07066716 0,10261015 ! response to fungus GO:0009620 19 18 0,000 0,07066716 0,10254541 ! peptide cross-linking GO:0018149 31 18 0,000 0,07066716 0,10248075 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,07066716 0,10241618 ! heart process GO:0003015 27 18 0,000 0,07066716 0,10235168 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,07066716 0,10228727 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,07066716 0,10222294 ! visual learning GO:0008542 35 18 0,000 0,07066716 0,10215869 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,07066716 0,10209452 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,07066716 0,10203043 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,07066716 0,10196642 ! vitamin transport GO:0051180 24 18 0,000 0,07066716 0,10190249 ! hormone transport GO:0009914 27 18 0,000 0,07066716 0,10183864 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,07066716 0,10177487 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,07066716 0,10171118 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,07066716 0,10164758 ! cell-cell recognition GO:0009988 20 18 0,000 0,07066716 0,10158405 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,07066716 0,1015206 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,07066716 0,10145722 ! regulation of glucose import GO:0046324 21 18 0,000 0,07066716 0,10139393 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,07066716 0,10133072 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,07066716 0,10126758 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,07066716 0,10120453 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,07066716 0,10114155 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,07444537 0,10648281 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,07444537 0,10641663 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,07444537 0,10635053 ! positive regulation of ossification GO:0045778 30 19 0,000 0,07444537 0,10628451 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,07444537 0,10621858 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,07444537 0,10615273 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,07444537 0,10608696 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,07444537 0,10602127 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,07444537 0,10595566 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,07444537 0,10589014 ! regeneration GO:0031099 32 19 0,000 0,07444537 0,10582469 ! response to alkaloid GO:0043279 32 19 0,000 0,07444537 0,10575933 ! sensory perception of taste GO:0050909 23 19 0,000 0,07444537 0,10569404 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,07444537 0,10562884 ! smooth muscle contraction GO:0006939 36 19 0,000 0,07444537 0,10556372 ! peroxisome organization GO:0007031 29 19 0,000 0,07444537 0,10549868 ! digestive system process GO:0022600 30 19 0,000 0,07444537 0,10543371 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,07444537 0,10536883 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,07444537 0,10530403 ! response to vitamin A GO:0033189 26 19 0,000 0,07444537 0,10523931 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,07444537 0,10517466 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,07444537 0,1051101 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,07444537 0,10504561 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,07444537 0,10498121 ! response to starvation GO:0042594 30 19 0,000 0,07444537 0,10491688 ! plasma membrane fusion GO:0045026 23 19 0,000 0,07444537 0,10485263 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,07444537 0,10478847 ! cytolysis GO:0019835 20 19 0,000 0,07444537 0,10472437 ! renal system process GO:0003014 35 19 0,000 0,07444537 0,10466036 ! vasodilation GO:0042311 33 19 0,000 0,07444537 0,10459643 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,07444537 0,10453257 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,07444537 0,10446879 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,07444537 0,10440509 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,07444537 0,10434147 ! sarcomere organization GO:0045214 23 19 0,000 0,07444537 0,10427792 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,07444537 0,10421446 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,07444537 0,10415107 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,07444537 0,10408775 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,07444537 0,10402452 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,07444537 0,10396136 ! protein stabilization GO:0050821 26 19 0,000 0,07444537 0,10389827 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,07820843 0,10908393 ! iron ion transport GO:0006826 37 20 0,000 0,07820843 0,10901782 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,07820843 0,10895179 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,07820843 0,10888583 ! response to vitamin GO:0033273 29 20 0,000 0,07820843 0,10881996 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,07820843 0,10875417 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,07820843 0,10868846 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,07820843 0,10862283 ! spinal cord development GO:0021510 31 20 0,000 0,07820843 0,10855727 ! response to ethanol GO:0045471 37 20 0,000 0,07820843 0,1084918 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,07820843 0,1084264 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,07820843 0,10836108 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,07820843 0,10829584 ! chromosome condensation GO:0030261 31 20 0,000 0,07820843 0,10823068 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,07820843 0,1081656 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,07820843 0,1081006 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,07820843 0,10803567 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,07820843 0,10797083 ! DNA modification GO:0006304 28 20 0,000 0,07820843 0,10790606 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,07820843 0,10784137 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,07820843 0,10777675 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,07820843 0,10771221 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,07820843 0,10764775 ! collagen catabolic process GO:0030574 25 20 0,000 0,07820843 0,10758337 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,07820843 0,10751907 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,07820843 0,10745484 ! alditol metabolic process GO:0019400 24 20 0,000 0,07820843 0,10739069 ! actin filament-based movement GO:0030048 34 20 0,000 0,07820843 0,10732661 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,08195641 0,11240295 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,08195641 0,11233596 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,08195641 0,11226906 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,08195641 0,11220223 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,08195641 0,11213548 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,08195641 0,11206882 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,08195641 0,11200223 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,08195641 0,11193572 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,08195641 0,11186929 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,08195641 0,11180294 ! phototransduction GO:0007602 25 21 0,000 0,08195641 0,11173666 ! dendrite development GO:0016358 35 21 0,000 0,08195641 0,11167047 ! visual behavior GO:0007632 39 21 0,000 0,08195641 0,11160435 ! ovarian follicle development GO:0001541 30 21 0,000 0,08195641 0,11153831 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,08195641 0,11147235 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,08195641 0,11140647 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,08195641 0,11134067 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,08195641 0,11127494 ! cell aging GO:0007569 32 21 0,000 0,08195641 0,11120929 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,08195641 0,11114372 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,08195641 0,11107823 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,08195641 0,11101281 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,08195641 0,11094747 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,08195641 0,11088221 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,08195641 0,11081702 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,08195641 0,11075191 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,08195641 0,11068688 ! fatty acid transport GO:0015908 30 21 0,000 0,08195641 0,11062192 ! platelet activation GO:0030168 28 21 0,000 0,08195641 0,11055704 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,08195641 0,11049223 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,08195641 0,1104275 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,08195641 0,11036285 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,08195641 0,11029827 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,08195641 0,11023377 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,08195641 0,11016934 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,08195641 0,11010499 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,08195641 0,11004072 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,08195641 0,10997652 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,08195641 0,10991239 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,08195641 0,10984834 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,08568937 0,11478482 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,08568937 0,11471801 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,08568937 0,11465127 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,08568937 0,11458462 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,08568937 0,11451804 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,08568937 0,11445153 ! molting cycle process GO:0022404 40 22 0,000 0,08568937 0,11438511 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,08568937 0,11431876 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,08568937 0,11425249 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,08568937 0,11418629 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,08568937 0,11412017 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,08568937 0,11405413 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,08568937 0,11398817 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,08568937 0,11392228 ! lysosome organization GO:0007040 37 22 0,000 0,08568937 0,11385647 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,08568937 0,11379073 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,08568937 0,11372507 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,08568937 0,11365948 ! regulation of behavior GO:0050795 38 22 0,000 0,08568937 0,11359397 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,08568937 0,11352854 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,08568937 0,11346318 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,08568937 0,11339789 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,08568937 0,11333269 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,08568937 0,11326755 ! blastocyst development GO:0001824 37 22 0,000 0,08568937 0,11320249 ! neural tube closure GO:0001843 33 22 0,000 0,08568937 0,11313751 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,08568937 0,1130726 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,08940735 0,11791107 ! neuron fate commitment GO:0048663 32 23 0,000 0,08940735 0,1178435 ! embryonic pattern specification GO:0009880 31 23 0,000 0,08940735 0,11777601 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,08940735 0,11770859 ! myelination GO:0042552 35 23 0,000 0,08940735 0,11764125 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,08940735 0,11757399 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,08940735 0,11750681 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,08940735 0,1174397 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,08940735 0,11737267 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,08940735 0,11730571 ! vesicle targeting GO:0006903 32 23 0,000 0,08940735 0,11723883 ! osteoblast differentiation GO:0001649 40 23 0,000 0,08940735 0,11717203 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,08940735 0,1171053 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,08940735 0,11703865 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,08940735 0,11697208 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,08940735 0,11690558 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,08940735 0,11683915 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,08940735 0,11677281 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,08940735 0,11670653 ! cell fate determination GO:0001709 45 23 0,000 0,08940735 0,11664034 ! pentose metabolic process GO:0019321 31 23 0,000 0,08940735 0,11657421 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,08940735 0,11650817 ! spermatid development GO:0007286 33 23 0,000 0,08940735 0,11644219 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,08940735 0,11637629 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,08940735 0,11631047 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,08940735 0,11624472 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,08940735 0,11617905 ! telomere organization GO:0032200 32 23 0,000 0,08940735 0,11611345 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,08940735 0,11604792 ! regulation of amine transport GO:0051952 38 23 0,000 0,08940735 0,11598247 ! liver development GO:0001889 40 23 0,000 0,08940735 0,11591709 ! initiation of viral infection GO:0019059 42 24 0,000 0,09311043 0,12065014 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,09311043 0,1205822 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,09311043 0,12051435 ! superoxide metabolic process GO:0006801 32 24 0,000 0,09311043 0,12044657 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,09311043 0,12037886 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,09311043 0,12031123 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,09311043 0,12024368 ! sperm motility GO:0030317 27 24 0,000 0,09311043 0,1201762 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,09311043 0,1201088 ! vacuole organization GO:0007033 39 24 0,000 0,09311043 0,12004148 ! receptor metabolic process GO:0043112 37 24 0,000 0,09311043 0,11997423 ! neural crest cell development GO:0014032 39 24 0,000 0,09311043 0,11990705 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,09311043 0,11983995 ! primary neural tube formation GO:0014020 35 24 0,000 0,09311043 0,11977293 ! base-excision repair GO:0006284 31 24 0,000 0,09311043 0,11970598 ! glutathione metabolic process GO:0006749 29 24 0,000 0,09311043 0,1196391 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,09311043 0,1195723 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,09311043 0,11950558 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,09311043 0,11943893 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,09679867 0,12410085 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,09679867 0,12403172 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,09679867 0,12396266 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,09679867 0,12389367 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,09679867 0,12382477 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,09679867 0,12375594 ! peptide transport GO:0015833 43 25 0,000 0,09679867 0,12368718 ! male gonad development GO:0008584 33 25 0,000 0,09679867 0,12361851 ! iron ion homeostasis GO:0055072 39 25 0,000 0,09679867 0,12354991 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,09679867 0,12348138 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,09679867 0,12341293 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,09679867 0,12334456 ! phospholipid transport GO:0015914 35 25 0,000 0,09679867 0,12327626 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,09679867 0,12320804 ! detection of light stimulus GO:0009583 30 25 0,000 0,09679867 0,1231399 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,09679867 0,12307182 GO:0045840|positive regulation of mitosis, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,09679867 0,12300383 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,10047211 0,12760124 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,10047211 0,12753082 ! translational initiation GO:0006413 43 26 0,000 0,10047211 0,12746048 ! regulation of pH GO:0006885 36 26 0,000 0,10047211 0,12739021 ! circadian rhythm GO:0007623 42 26 0,000 0,10047211 0,12732003 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,10047211 0,12724992 ! post-embryonic development GO:0009791 42 26 0,000 0,10047211 0,12717988 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,10047211 0,12710993 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,10047211 0,12704005 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,10047211 0,12697025 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,10047211 0,12690052 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,10413082 0,13144944 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,10413082 0,13137734 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,10413082 0,13130531 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,10413082 0,13123336 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,10413082 0,13116149 ! catechol metabolic process GO:0009712 43 27 0,000 0,10413082 0,1310897 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,10413082 0,13101799 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,10413082 0,13094636 ! myofibril assembly GO:0030239 36 27 0,000 0,10413082 0,1308748 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,10413082 0,13080332 ! response to ionizing radiation GO:0010212 47 27 0,000 0,10413082 0,13073193 ! natural killer cell activation GO:0030101 35 27 0,000 0,10413082 0,1306606 ! lipid oxidation GO:0034440 38 27 0,000 0,10413082 0,13058936 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,10413082 0,13051819 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,10413082 0,13044711 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,10413082 0,1303761 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,10413082 0,13030516 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,10413082 0,13023431 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,10413082 0,13016353 ! gene silencing GO:0016458 41 27 0,000 0,10413082 0,13009282 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,10777486 0,1345723 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,10777486 0,13449928 ! phenol metabolic process GO:0018958 44 28 0,000 0,10777486 0,13442634 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,10777486 0,13435348 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,10777486 0,1342807 ! cell junction assembly GO:0034329 56 28 0,000 0,10777486 0,134208 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,10777486 0,13413538 ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,10777486 0,13406283 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,10777486 0,13399037 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,10777486 0,13391798 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,10777486 0,13384567 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,10777486 0,13377344 ! mesoderm formation GO:0001707 46 28 0,000 0,10777486 0,13370128 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,10777486 0,13362921 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,10777486 0,13355721 ! ensheathment of neurons GO:0007272 43 28 0,000 0,10777486 0,13348529 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,10777486 0,13341344 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,10777486 0,13334168 ! neural tube formation GO:0001841 41 28 0,000 0,10777486 0,13326999 ! placenta development GO:0001890 37 28 0,000 0,10777486 0,13319838 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,11140429 0,13761002 ! ovulation cycle process GO:0022602 41 29 0,000 0,11140429 0,13753615 ! protein targeting to membrane GO:0006612 53 29 0,000 0,11140429 0,13746237 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,11140429 0,13738866 ! mismatch repair GO:0006298 34 29 0,000 0,11140429 0,13731504 ! muscle cell development GO:0055001 38 29 0,000 0,11140429 0,13724149 ! formation of primary germ layer GO:0001704 48 29 0,000 0,11140429 0,13716802 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,11140429 0,13709463 ! eye morphogenesis GO:0048592 51 29 0,000 0,11140429 0,13702131 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,11140429 0,13694808 ! tissue homeostasis GO:0001894 42 29 0,000 0,11140429 0,13687492 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,11501915 0,14124082 ! collagen metabolic process GO:0032963 40 30 0,000 0,11501915 0,14116545 ! organic anion transport GO:0015711 51 30 0,000 0,11501915 0,14109016 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,11501915 0,14101495 ! spliceosome assembly GO:0000245 49 30 0,000 0,11501915 0,14093983 ! spindle organization GO:0007051 37 30 0,000 0,11501915 0,14086478 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,11501915 0,14078981 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,11501915 0,14071492 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,11501915 0,14064011 ! ceramide metabolic process GO:0006672 43 30 0,000 0,11501915 0,14056538 ! ovulation cycle GO:0042698 43 30 0,000 0,11501915 0,14049073 ! hindbrain development GO:0030902 45 30 0,000 0,11501915 0,14041616 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,11501915 0,14034167 ! adult locomotory behavior GO:0008344 47 30 0,000 0,11501915 0,14026726 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,11501915 0,14019293 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,11501915 0,14011867 ! response to heat GO:0009408 41 30 0,000 0,11501915 0,1400445 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,11501915 0,1399704 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,11861952 0,14427546 ! negative regulation of secretion GO:0051048 49 31 0,000 0,11861952 0,14419921 ! glial cell differentiation GO:0010001 55 31 0,000 0,11861952 0,14412303 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,11861952 0,14404694 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,11861952 0,14397092 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,11861952 0,14389499 ! odontogenesis GO:0042476 50 31 0,000 0,11861952 0,14381914 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,11861952 0,14374336 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,11861952 0,14366767 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,11861952 0,14359205 ! metanephros development GO:0001656 58 31 0,000 0,11861952 0,14351652 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,11861952 0,14344106 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,11861952 0,14336569 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,11861952 0,14329039 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,11861952 0,14321517 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,11861952 0,14314003 ! RNA modification GO:0009451 40 31 0,000 0,11861952 0,14306497 ! regulation of muscle development GO:0048634 48 32 0,000 0,12220545 0,14731265 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,12220545 0,14723548 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,12220545 0,14715839 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,12220545 0,14708139 ! meiosis I GO:0007127 52 32 0,000 0,12220545 0,14700446 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,12220545 0,14692762 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,12220545 0,14685085 ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,12220545 0,14677417 ! peripheral nervous system development GO:0007422 53 32 0,000 0,12220545 0,14669756 ! regulation of protein stability GO:0031647 48 32 0,000 0,12220545 0,14662104 ! cytokine production GO:0001816 44 32 0,000 0,12220545 0,1465446 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,12220545 0,14646823 ! vesicle localization GO:0051648 47 32 0,000 0,12220545 0,14639194 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,12577699 0,15059192 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,12577699 0,15051357 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,12577699 0,1504353 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,12577699 0,15035711 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,12577699 0,150279 ! sister chromatid segregation GO:0000819 46 33 0,000 0,12577699 0,15020098 ! ear morphogenesis GO:0042471 42 33 0,000 0,12577699 0,15012303 ! actomyosin structure organization GO:0031032 43 33 0,000 0,12577699 0,15004517 ! cell junction organization GO:0034330 63 33 0,000 0,12577699 0,14996738 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,12577699 0,14988968 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,12577699 0,14981206 ! nucleus organization GO:0006997 49 33 0,000 0,12577699 0,14973451 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,12577699 0,14965705 ! female gonad development GO:0008585 49 33 0,000 0,12577699 0,14957967 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,12577699 0,14950237 ! positive regulation of cell development GO:0010720 54 33 0,000 0,12577699 0,14942515 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,12577699 0,149348 ! regulation of proteolysis GO:0030162 50 33 0,000 0,12577699 0,14927094 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,12577699 0,14919396 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,12577699 0,14911705 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,12577699 0,14904023 ! cytokinesis GO:0000910 52 33 0,000 0,12577699 0,14896348 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,12933421 0,15309762 ! mRNA catabolic process GO:0006402 48 34 0,000 0,12933421 0,15301887 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,12933421 0,15294019 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,12933421 0,1528616 ! feeding behavior GO:0007631 45 34 0,000 0,12933421 0,15278309 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,12933421 0,15270466 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,12933421 0,15262631 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,12933421 0,15254804 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,12933421 0,15246985 ! neuron migration GO:0001764 46 34 0,000 0,12933421 0,15239174 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,12933421 0,15231371 ! female gamete generation GO:0007292 43 34 0,000 0,12933421 0,15223576 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,12933421 0,15215789 ! polyol metabolic process GO:0019751 44 34 0,000 0,12933421 0,1520801 ! aerobic respiration GO:0009060 47 34 0,000 0,12933421 0,15200239 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,12933421 0,15192476 ! embryonic organ development GO:0048568 45 34 0,000 0,12933421 0,1518472 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,12933421 0,15176973 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,13287715 0,15584775 ! Notch signaling pathway GO:0007219 56 35 0,000 0,13287715 0,15576832 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,13287715 0,15568897 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,13287715 0,1556097 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,13287715 0,15553051 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,13287715 0,1554514 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,13287715 0,15537237 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,13287715 0,15529342 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,13287715 0,15521455 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,13287715 0,15513576 ! glycogen metabolic process GO:0005977 48 35 0,000 0,13287715 0,15505705 ! pigment metabolic process GO:0042440 61 35 0,000 0,13287715 0,15497842 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,13640588 0,15901344 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,13640588 0,15893289 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,13640588 0,15885241 ! negative regulation of binding GO:0051100 58 36 0,000 0,13640588 0,15877202 ! neural tube development GO:0021915 50 36 0,000 0,13640588 0,15869171 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,13640588 0,15861149 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,13640588 0,15853134 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,13640588 0,15845127 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,13640588 0,15837129 ! glucan metabolic process GO:0044042 49 36 0,000 0,13640588 0,15829138 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,13992045 0,16228796 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,13992045 0,16220616 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,13992045 0,16212445 ! learning GO:0007612 67 37 0,000 0,13992045 0,16204281 ! ion transmembrane transport GO:0034220 56 37 0,000 0,13992045 0,16196126 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,13992045 0,16187979 ! regulation of protein secretion GO:0050708 51 37 0,000 0,13992045 0,16179841 ! amino acid activation GO:0043038 52 37 0,000 0,13992045 0,1617171 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,13992045 0,16163588 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,14342091 0,16559644 ! gliogenesis GO:0042063 71 38 0,000 0,14342091 0,16551335 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,14342091 0,16543034 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,14342091 0,16534742 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,14342091 0,16526458 ! mesenchymal cell development GO:0014031 64 38 0,000 0,14342091 0,16518182 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,14342091 0,16509915 ! maintenance of location in cell GO:0051651 69 38 0,000 0,14342091 0,16501656 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,14690733 0,16894343 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,14690733 0,16885901 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,14690733 0,16877466 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,14690733 0,1686904 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,14690733 0,16860622 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,14690733 0,16852213 ! male sex differentiation GO:0046661 53 39 0,000 0,14690733 0,16843812 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,14690733 0,1683542 ! JNK cascade GO:0007254 54 39 0,000 0,14690733 0,16827035 ! developmental growth GO:0048589 62 39 0,000 0,14690733 0,1681866 ! synapse organization GO:0050808 55 39 0,000 0,14690733 0,16810292 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,15037976 0,17199078 ! response to calcium ion GO:0051592 58 40 0,000 0,15037976 0,1719053 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,15037976 0,1718199 ! regulation of tube size GO:0035150 60 40 0,000 0,15037976 0,17173459 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,15037976 0,17164936 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,15037976 0,17156421 ! peptide metabolic process GO:0006518 56 40 0,000 0,15037976 0,17147916 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,15037976 0,17139418 ! inner ear development GO:0048839 57 40 0,000 0,15037976 0,17130929 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,15037976 0,17122448 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! double-strand break repair GO:0006302 67 40 0,000 0,15037976 0,17113976 ! B cell differentiation GO:0030183 62 40 0,000 0,15037976 0,17105512 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,15037976 0,17097057 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,15037976 0,1708861 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,15037976 0,17080171 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,15383826 0,17464363 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,15383826 0,17455747 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,15383826 0,1744714 ! glucose transport GO:0015758 52 41 0,000 0,15383826 0,17438541 ! endosome transport GO:0016197 71 41 0,000 0,15383826 0,1742995 ! striated muscle contraction GO:0006941 62 41 0,000 0,15383826 0,17421368 ! biopolymer methylation GO:0043414 62 41 0,000 0,15383826 0,17412795 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,15383826 0,1740423 ! mitochondrial transport GO:0006839 60 42 0,000 0,15728287 0,17785182 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,15728287 0,17776442 ! cellular component disassembly GO:0022411 64 42 0,000 0,15728287 0,17767711 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,15728287 0,17758989 ! hexose transport GO:0008645 54 42 0,000 0,15728287 0,17750275 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,15728287 0,17741569 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,15728287 0,17732873 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,15728287 0,17724184 ! excretion GO:0007588 63 42 0,000 0,15728287 0,17715504 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,15728287 0,17706833 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,15728287 0,1769817 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,15728287 0,17689516 ! regulation of cell shape GO:0008360 78 42 0,000 0,15728287 0,1768087 ! leukocyte migration GO:0050900 60 43 0,000 0,16071366 0,18057714 ! neuromuscular process GO:0050905 79 43 0,000 0,16071366 0,18048897 ! activation of caspase activity GO:0006919 65 43 0,000 0,16071366 0,18040088 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,16071366 0,18031288 ! tRNA processing GO:0008033 49 43 0,000 0,16071366 0,18022497 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,16071366 0,18013714 ! methylation GO:0032259 64 43 0,000 0,16071366 0,1800494 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,16413067 0,183788 ! glycolysis GO:0006096 53 44 0,000 0,16413067 0,18369856 ! regulation of action potential GO:0001508 71 44 0,000 0,16413067 0,18360921 ! regulation of ion transport GO:0043269 57 44 0,000 0,16413067 0,18351995 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,16413067 0,18343078 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,16413067 0,18334169 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,16413067 0,18325269 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,16413067 0,18316378 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,16413067 0,18307495 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,16413067 0,18298621 ! RNA catabolic process GO:0006401 64 45 0,000 0,16753397 0,18668999 ! regulation of translational initiation GO:0006446 64 45 0,000 0,16753397 0,18659958 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,16753397 0,18650926 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,16753397 0,18641903 ! cell recognition GO:0008037 58 45 0,000 0,16753397 0,18632888 ! cell maturation GO:0048469 60 45 0,000 0,16753397 0,18623883 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,17092361 0,18991512 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,17092361 0,18982342 ! cell redox homeostasis GO:0045454 63 46 0,000 0,17092361 0,1897318 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,17092361 0,18964028 ! regulation of ossification GO:0030278 71 46 0,000 0,17092361 0,18954884 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,17429963 0,19319959 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,17429963 0,19310653 ! endocrine system development GO:0035270 83 47 0,000 0,17429963 0,19301356 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,17429963 0,19292067 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,17429963 0,19282788 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,17429963 0,19273517 ! chloride transport GO:0006821 67 48 0,000 0,17766211 0,19635889 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,17766211 0,19626458 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,17766211 0,19617035 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,17766211 0,19607622 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,17766211 0,19598218 ! gastrulation GO:0007369 73 48 0,000 0,17766211 0,19588823 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,17766211 0,19579437 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,17766211 0,1957006 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,17766211 0,19560692 ! regulation of endocytosis GO:0030100 63 48 0,000 0,17766211 0,19551332 ! nuclear export GO:0051168 69 48 0,000 0,17766211 0,19541982 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,18101108 0,19900836 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,18101108 0,19891327 ! sensory perception of smell GO:0007608 61 49 0,000 0,18101108 0,19881828 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,18101108 0,19872338 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,18101108 0,19862857 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,18101108 0,19853385 ! germ cell development GO:0007281 68 49 0,000 0,18101108 0,19843922 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,18101108 0,19834468 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,18101108 0,19825023 ! cartilage development GO:0051216 70 49 0,000 0,18101108 0,19815587 ! maintenance of location GO:0051235 84 49 0,000 0,18101108 0,1980616 ! regulation of actin filament length GO:0030832 72 50 0,000 0,18434661 0,2016154 ! ear development GO:0043583 72 50 0,000 0,18434661 0,20151958 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,18434661 0,20142384 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,18434661 0,2013282 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,18434661 0,20123265 ! proton transport GO:0015992 75 50 0,000 0,18434661 0,20113719 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,18434661 0,20104182 ! positive regulation of secretion GO:0051047 71 51 0,000 0,18766874 0,20456782 ! hydrogen transport GO:0006818 77 51 0,000 0,18766874 0,20447091 ! muscle fiber development GO:0048747 74 51 0,000 0,18766874 0,2043741 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,18766874 0,20427738 ! adult behavior GO:0030534 80 51 0,000 0,18766874 0,20418074 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,18766874 0,20408421 ! transition metal ion transport GO:0000041 74 52 0,000 0,19097753 0,20758427 ! regulation of cellular component size GO:0032535 74 52 0,000 0,19097753 0,20748621 ! aging GO:0007568 79 52 0,000 0,19097753 0,20738825 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,19097753 0,20729038 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,19097753 0,2071926 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,19427303 0,21066854 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,19427303 0,21056926 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,19427303 0,21047007 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,19427303 0,21037098 ! kidney development GO:0001822 90 53 0,000 0,19427303 0,21027198 ! single fertilization GO:0007338 59 53 0,000 0,19427303 0,21017308 ! amino acid transport GO:0006865 84 54 0,000 0,19755529 0,2136235 ! regulation of mitosis GO:0007088 84 54 0,000 0,19755529 0,21352311 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,19755529 0,21342282 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,19755529 0,21332262 ! DNA catabolic process GO:0006308 67 54 0,000 0,19755529 0,21322251 ! detection of external stimulus GO:0009581 66 54 0,000 0,19755529 0,2131225 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,19755529 0,21302259 ! exocytosis GO:0006887 74 55 0,000 0,20082438 0,21644614 ! mesoderm development GO:0007498 76 55 0,000 0,20082438 0,21634476 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,20082438 0,21624348 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,20082438 0,21614229 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,20408033 0,21954385 ! carbohydrate transport GO:0008643 74 57 0,000 0,2073232 0,22292817 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,2073232 0,222824 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,2073232 0,22271993 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,2073232 0,22261595 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,2073232 0,22251207 ! camera-type eye development GO:0043010 88 57 0,000 0,2073232 0,22240829 ! secondary metabolic process GO:0019748 84 57 0,000 0,2073232 0,2223046 ! developmental maturation GO:0021700 75 57 0,000 0,2073232 0,22220101 ! gonad development GO:0008406 79 57 0,000 0,2073232 0,22209751 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,21055305 0,22545252 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,21055305 0,22534761 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,21055305 0,22524279 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,21376992 0,22857778 ! actin filament organization GO:0007015 95 59 0,000 0,21376992 0,22847156 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,21376992 0,22836545 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,21697386 0,23168054 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,21697386 0,23157303 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,21697386 0,23146562 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,21697386 0,23135831 ! regulation of heart contraction GO:0008016 91 60 0,000 0,21697386 0,2312511 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,21697386 0,23114399 ! fertilization GO:0009566 68 60 0,000 0,21697386 0,23103698 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,22016493 0,2343264 ! meiosis GO:0007126 96 61 0,000 0,22016493 0,23421801 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,22016493 0,23410973 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,22016493 0,23400155 ! urogenital system development GO:0001655 101 61 0,000 0,22016493 0,23389346 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,22016493 0,23378548 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,22016493 0,23367759 ! extracellular matrix organization GO:0030198 103 61 0,000 0,22016493 0,23356981 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,22016493 0,23346212 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,22016493 0,23335454 ! neurotransmitter transport GO:0006836 81 62 0,000 0,22334318 0,23661415 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,22334318 0,23650521 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,22334318 0,23639637 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,22334318 0,23628764 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,22334318 0,236179 ! meiotic cell cycle GO:0051321 97 62 0,000 0,22334318 0,23607046 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,22650866 0,23930635 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,22650866 0,23919647 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,22966142 0,24241453 ! negative regulation of cell size GO:0045792 108 64 0,000 0,22966142 0,24230333 ! appendage morphogenesis GO:0035107 93 64 0,000 0,22966142 0,24219223 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,22966142 0,24208124 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,22966142 0,24197035 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,22966142 0,24185955 ! hexose catabolic process GO:0019320 82 64 0,000 0,22966142 0,24174886 ! adaptive immune response GO:0002250 94 64 0,000 0,22966142 0,24163827 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,23280151 0,24483012 ! appendage development GO:0048736 94 65 0,000 0,23280151 0,24471822 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,23280151 0,24460643 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,23280151 0,24449473 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,23280151 0,24438314 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,23592897 0,24755321 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,23592897 0,24744033 ! axon guidance GO:0007411 99 66 0,000 0,23592897 0,24732755 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,23592897 0,24721487 ! learning or memory GO:0007611 123 68 0,000 0,24214625 0,25361401 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,24214625 0,25349857 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,24214625 0,25338324 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,24214625 0,25326802 ! rhythmic process GO:0048511 105 68 0,000 0,24214625 0,25315289 ! inorganic anion transport GO:0015698 93 68 0,000 0,24214625 0,25303788 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,24523615 0,25615039 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,24523615 0,25603411 ! response to drug GO:0042493 108 69 0,000 0,24523615 0,25591794 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,24523615 0,25580188 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,24831364 0,25889454 ! humoral immune response GO:0006959 86 70 0,000 0,24831364 0,25877724 ! eye development GO:0001654 111 70 0,000 0,24831364 0,25866004 ! amine transport GO:0015837 101 70 0,000 0,24831364 0,25854294 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,25137875 0,26161589 ! muscle cell differentiation GO:0042692 104 71 0,000 0,25137875 0,26149757 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,25137875 0,26137935 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,25137875 0,26126124 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,25137875 0,26114323 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,25137875 0,26102534 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,25443154 0,26407605 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,25443154 0,26395694 ! negative regulation of transport GO:0051051 116 73 0,000 0,25747205 0,26699086 ! regulation of blood pressure GO:0008217 107 73 0,000 0,25747205 0,26687054 ! tube morphogenesis GO:0035239 118 73 0,000 0,25747205 0,26675032 ! mitochondrion organization GO:0007005 104 73 0,000 0,25747205 0,26663022 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,25747205 0,26651023 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,26050034 0,26952352 ! digestion GO:0007586 97 74 0,000 0,26050034 0,26940233 ! protein import into nucleus GO:0006606 118 74 0,000 0,26050034 0,26928125 ! negative regulation of growth GO:0045926 123 75 0,000 0,26351645 0,27227666 ! response to nutrient GO:0007584 104 75 0,000 0,26351645 0,2721544 ! regulation of ligase activity GO:0051340 114 75 0,000 0,26351645 0,27203225 ! nuclear import GO:0051170 121 75 0,000 0,26351645 0,2719102 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,26351645 0,27178827 ! amine biosynthetic process GO:0009309 97 76 0,000 0,26652044 0,27476334 ! tRNA metabolic process GO:0006399 95 76 0,000 0,26652044 0,27464023 ! response to unfolded protein GO:0006986 99 76 0,000 0,26652044 0,27451724 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,26652044 0,27439436 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,26951234 0,2773505 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,26951234 0,27722647 ! sex differentiation GO:0007548 105 77 0,000 0,26951234 0,27710254 ! protein ubiquitination GO:0016567 125 77 0,000 0,26951234 0,27697872 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,26951234 0,27685501 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,26951234 0,27673142 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,26951234 0,27660793 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,27249221 0,27954152 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,27249221 0,27941689 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,27546009 0,28233432 ! cellular respiration GO:0045333 107 79 0,000 0,27546009 0,28220856 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,27546009 0,28208291 ! regulation of lyase activity GO:0051339 133 79 0,000 0,27546009 0,28195737 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,27546009 0,28183194 ! chromatin assembly GO:0031497 102 80 0,000 0,27841604 0,28472961 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,27841604 0,28460306 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,27841604 0,28447663 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,27841604 0,28435031 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,27841604 0,2842241 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,28136009 0,28710214 ! mRNA transport GO:0051028 121 81 0,000 0,28136009 0,28697482 ! response to protein stimulus GO:0051789 111 81 0,000 0,28136009 0,28684761 ! regulation of neurological system process GO:0031644 122 81 0,000 0,28136009 0,28672052 ! vitamin metabolic process GO:0006766 103 81 0,000 0,28136009 0,28659354 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,28721272 0,29242553 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,28721272 0,29229613 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,29012139 0,2951257 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,29012139 0,29499522 ! sterol metabolic process GO:0016125 120 84 0,000 0,29012139 0,29486487 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,29301835 0,29767766 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,29590366 0,30047612 ! cell cycle arrest GO:0007050 150 86 0,000 0,29590366 0,30034352 ! nucleosome organization GO:0034728 114 87 0,000 0,29877736 0,30312657 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,29877736 0,30299291 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! female pregnancy GO:0007565 130 87 0,000 0,29877736 0,30285938 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,29877736 0,30272596 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,30163949 0,30549134 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,30163949 0,30535688 ! establishment of RNA localization GO:0051236 128 88 0,000 0,30163949 0,30522254 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,30163949 0,30508832 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,30449011 0,30783615 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,30449011 0,3077009 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,30732925 0,31043359 ! hormone metabolic process GO:0042445 121 90 0,000 0,30732925 0,31029731 ! RNA localization GO:0006403 135 91 0,000 0,31015696 0,31301493 ! ATP metabolic process GO:0046034 137 91 0,000 0,31015696 0,31287764 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,3129733 0,31558027 ! DNA recombination GO:0006310 146 92 0,000 0,3129733 0,31544197 ! sulfur metabolic process GO:0006790 118 92 0,000 0,3129733 0,3153038 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,3157783 0,3179904 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,3157783 0,31785124 ! electron transport chain GO:0022900 123 94 0,000 0,318572 0,32052301 ! angiogenesis GO:0001525 149 95 0,000 0,32135446 0,32318113 ! carboxylic acid transport GO:0046942 147 95 0,000 0,32135446 0,32303988 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,32412572 0,32568333 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,32412572 0,32554111 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,32412572 0,32539902 ! protein maturation GO:0051604 129 96 0,000 0,32412572 0,32525704 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,32688581 0,32788372 ! extracellular structure organization GO:0043062 156 99 0,000 0,33237271 0,33324204 ! protein import GO:0017038 156 99 0,000 0,33237271 0,33309684 ! regulation of translation GO:0006417 151 100 0,000 0,33509961 0,3356834 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,33509961 0,33553726 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,33509961 0,33539125 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,33509961 0,33524536 ! protein localization in organelle GO:0033365 161 100 0,000 0,33509961 0,33509961