pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1119-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 4,000 1,141E-09 2,788E-06 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 3,000 7,854E-08 9,593E-05 ! nuclear migration GO:0007097 13 6 2,000 2,355E-07 1,918E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 2,355E-07 1,438E-04 GO:0031272|regulation of pseudopodium assembly, ! male sex determination GO:0030238 15 7 2,000 4,114E-07 2,01E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 6,572E-07 2,676E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 6,572E-07 2,294E-04 ! macrophage differentiation GO:0030225 15 9 2,000 9,841E-07 3,005E-04 ! nucleus localization GO:0051647 22 11 2,000 1,927E-06 5,23E-04 ! regulation of cell projection assembly GO:0060491 33 12 2,000 2,565E-06 6,265E-04 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 3,151E-06 6,999E-04 ! leukocyte differentiation GO:0002521 232 98 4,000 3,315E-06 6,748E-04 ! filopodium assembly GO:0046847 42 17 2,000 7,861E-06 1,477E-03 ! response to UV GO:0009411 120 55 3,000 8,203E-06 1,431E-03 ! regulation of DNA replication GO:0006275 105 56 3,000 8,819E-06 1,436E-03 ! microspike assembly GO:0030035 46 18 2,000 9,418E-06 1,438E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 9,468E-06 1,361E-03 ! regulation of protein complex assembly GO:0043254 132 63 3,000 1,413E-05 1,917E-03 ! regulation of lipid metabolic process GO:0019216 132 66 3,000 1,7E-05 2,186E-03 ! negative regulation of cell growth GO:0030308 142 67 3,000 1,805E-05 2,205E-03 ! negative regulation of cell size GO:0045792 144 69 3,000 2,029E-05 2,36E-03 ! lung development GO:0030324 165 69 3,000 2,029E-05 2,253E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 2,313E-05 2,457E-03 ! sex determination GO:0007530 48 24 2,000 2,313E-05 2,354E-03 ! respiratory tube development GO:0030323 171 72 3,000 2,402E-05 2,347E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 2,624E-05 2,465E-03 ! negative regulation of DNA replication GO:0008156 45 25 2,000 2,624E-05 2,374E-03 ! interaction with host GO:0051701 66 25 2,000 2,624E-05 2,289E-03 ! protein tetramerization GO:0051262 57 25 2,000 2,624E-05 2,21E-03 ! respiratory system development GO:0060541 175 74 3,000 2,677E-05 2,18E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 3,326E-05 2,621E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 3,326E-05 2,539E-03 ! protein oligomerization GO:0051259 149 79 3,000 3,465E-05 2,565E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 3,719E-05 2,672E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 4,141E-05 2,89E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 4,593E-05 3,117E-03 ! negative regulation of growth GO:0045926 168 85 3,000 4,621E-05 3,051E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 5,077E-05 3,264E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 1,000 5,234E-05 3,279E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 5,234E-05 3,197E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 5,234E-05 3,119E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 5,234E-05 3,044E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 5,234E-05 2,974E-03 ! negative regulation of T cell mediated immunity GO:0002710 15 5 1,000 5,234E-05 2,906E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! protein insertion into membrane GO:0051205 17 5 1,000 5,234E-05 2,841E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 6,725E-05 3,572E-03 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 7,343E-05 3,817E-03 ! opsonization GO:0008228 8 6 1,000 7,839E-05 3,99E-03 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 7,839E-05 3,908E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 7,839E-05 3,83E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 8,058E-05 3,86E-03 ! tissue remodeling GO:0048771 78 37 2,000 8,689E-05 4,082E-03 ! DNA integrity checkpoint GO:0031570 82 38 2,000 9,418E-05 4,341E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 9,418E-05 4,261E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 1,096E-04 4,867E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,096E-04 4,781E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 1,096E-04 4,697E-03 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 1,000 1,096E-04 4,616E-03 ! vesicle fusion GO:0006906 20 7 1,000 1,096E-04 4,537E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 1,096E-04 4,462E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,096E-04 4,389E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,096E-04 4,318E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 1,000 1,096E-04 4,249E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 1,096E-04 4,183E-03 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 1,184E-04 4,45E-03 ! T cell differentiation GO:0030217 93 42 2,000 1,273E-04 4,712E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,459E-04 5,32E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,459E-04 5,241E-03 ! ER overload response GO:0006983 13 8 1,000 1,459E-04 5,165E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 1,459E-04 5,092E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,459E-04 5,02E-03 ! gas homeostasis GO:0033483 14 8 1,000 1,459E-04 4,95E-03 ! response to tumor cell GO:0002347 16 8 1,000 1,459E-04 4,882E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 1,459E-04 4,816E-03 ! lymph node development GO:0048535 11 8 1,000 1,459E-04 4,752E-03 ! negative regulation of DNA replication initiation GO:0032297 10 8 1,000 1,459E-04 4,69E-03 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,459E-04 4,629E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 1,459E-04 4,569E-03 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 1,459E-04 4,512E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,566E-04 4,782E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 1,566E-04 4,722E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,672E-04 4,982E-03 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 1,672E-04 4,922E-03 ! cell growth GO:0016049 90 46 2,000 1,672E-04 4,863E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 1,783E-04 5,125E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,873E-04 5,32E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 1,873E-04 5,259E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 1,873E-04 5,199E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,873E-04 5,141E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 1,873E-04 5,084E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 1,873E-04 5,028E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 1,000 1,873E-04 4,973E-03 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of DNA binding GO:0043388 83 48 2,000 1,899E-04 4,988E-03 ! regulation of cell projection organization GO:0031344 135 51 2,000 2,275E-04 5,913E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 2,338E-04 6,011E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 2,338E-04 5,949E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 2,338E-04 5,887E-03 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 2,338E-04 5,827E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 2,338E-04 5,769E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 2,338E-04 5,711E-03 ! positive regulation of phagocytosis GO:0050766 14 10 1,000 2,338E-04 5,654E-03 ! induction of an organ GO:0001759 17 10 1,000 2,338E-04 5,599E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,338E-04 5,545E-03 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 2,338E-04 5,491E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 2,338E-04 5,439E-03 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of immune effector process GO:0002698 23 10 1,000 2,338E-04 5,388E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,338E-04 5,337E-03 ! positive regulation of binding GO:0051099 88 52 2,000 2,41E-04 5,452E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,853E-04 6,394E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,853E-04 6,336E-03 ! regulation of intracellular pH GO:0051453 21 11 1,000 2,853E-04 6,279E-03 ! chondrocyte differentiation GO:0002062 27 11 1,000 2,853E-04 6,223E-03 ! regulation of smoothened signaling pathway GO:0008589 27 11 1,000 2,853E-04 6,168E-03 ! nitric oxide metabolic process GO:0046209 17 11 1,000 2,853E-04 6,114E-03 GO:0006809|nitric oxide biosynthetic process, ! embryonic gut development GO:0048566 19 11 1,000 2,853E-04 6,06E-03 ! regulation of embryonic development GO:0045995 35 11 1,000 2,853E-04 6,008E-03 ! positive regulation of cell migration GO:0030335 137 58 2,000 3,332E-04 6,957E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 3,418E-04 7,077E-03 ! virus-host interaction GO:0019048 30 12 1,000 3,418E-04 7,017E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 3,418E-04 6,959E-03 ! entry into host cell GO:0030260 34 12 1,000 3,418E-04 6,902E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 17 12 1,000 3,418E-04 6,845E-03 ! histone acetylation GO:0016573 27 12 1,000 3,418E-04 6,789E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,418E-04 6,735E-03 ! developmental induction GO:0031128 22 12 1,000 3,418E-04 6,681E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 3,418E-04 6,628E-03 ! establishment of organelle localization GO:0051656 122 59 2,000 3,505E-04 6,742E-03 ! organelle fusion GO:0048284 36 13 1,000 4,034E-04 7,699E-03 ! response to X-ray GO:0010165 28 13 1,000 4,034E-04 7,639E-03 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 4,034E-04 7,58E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 4,034E-04 7,522E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 4,034E-04 7,465E-03 ! gland morphogenesis GO:0022612 31 13 1,000 4,034E-04 7,409E-03 ! viral reproductive process GO:0022415 132 62 2,000 4,057E-04 7,396E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 4,455E-04 8,061E-03 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 4,455E-04 8,002E-03 ! positive regulation of cell motion GO:0051272 157 65 2,000 4,662E-04 8,314E-03 ! lipid localization GO:0010876 32 14 1,000 4,699E-04 8,319E-03 GO:0019915|lipid storage, ! regulation of cellular pH GO:0030641 27 14 1,000 4,699E-04 8,259E-03 ! response to gamma radiation GO:0010332 30 14 1,000 4,699E-04 8,2E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 4,699E-04 8,142E-03 ! positive regulation of protein polymerization GO:0032273 27 14 1,000 4,699E-04 8,084E-03 ! myeloid cell differentiation GO:0030099 126 67 2,000 5,096E-04 8,707E-03 ! viral reproduction GO:0016032 142 68 2,000 5,323E-04 9,03E-03 ! cell projection assembly GO:0030031 138 68 2,000 5,323E-04 8,968E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 5,414E-04 9,059E-03 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 5,414E-04 8,997E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 5,414E-04 8,936E-03 ! G1/S transition checkpoint GO:0031575 37 15 1,000 5,414E-04 8,876E-03 ! regulation of vasodilation GO:0042312 27 15 1,000 5,414E-04 8,817E-03 ! regulation of T cell mediated immunity GO:0002709 36 15 1,000 5,414E-04 8,759E-03 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 5,414E-04 8,701E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 5,556E-04 8,871E-03 ! negative regulation of kinase activity GO:0033673 145 70 2,000 5,795E-04 9,192E-03 ! cell cycle checkpoint GO:0000075 145 71 2,000 6,04E-04 9,52E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 6,178E-04 9,675E-03 ! negative regulation of immune response GO:0050777 38 16 1,000 6,178E-04 9,613E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 6,178E-04 9,552E-03 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 6,292E-04 9,668E-03 ! negative regulation of transferase activity GO:0051348 155 74 2,000 6,817E-04 0,01040832 ! organelle localization GO:0051640 155 74 2,000 6,817E-04 0,01034368 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 6,991E-04 0,01054277 ! lymphocyte differentiation GO:0030098 193 76 2,000 7,368E-04 0,01104315 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 7,853E-04 0,01169843 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 7,853E-04 0,01162754 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 7,947E-04 0,01169567 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 8,764E-04 0,01282063 ! response to fungus GO:0009620 26 19 1,000 8,764E-04 0,01274432 ! response to hypoxia GO:0001666 178 81 2,000 8,869E-04 0,01282008 ! regulation of peptidase activity GO:0052547 150 82 2,000 9,19E-04 0,01320675 ! protein import into nucleus GO:0006606 174 82 2,000 9,19E-04 0,01312952 ! response to oxygen levels GO:0070482 183 83 2,000 9,519E-04 0,01352026 ! nuclear import GO:0051170 177 83 2,000 9,519E-04 0,01344211 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 9,723E-04 0,01365161 ! protein amino acid acetylation GO:0006473 41 20 1,000 9,723E-04 0,0135736 ! transcription from RNA polymerase III promoter GO:0006383 46 20 1,000 9,723E-04 0,01349647 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 9,723E-04 0,01342022 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 9,723E-04 0,01334483 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 9,723E-04 0,01327028 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 1,000 9,723E-04 0,01319655 ! T cell activation GO:0042110 189 84 2,000 9,855E-04 0,01330179 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 1,02E-03 0,01368998 ! positive regulation of cell activation GO:0050867 161 86 2,000 1,055E-03 0,01408395 GO:0002696|positive regulation of leukocyte activation, ! regulation of cell killing GO:0031341 46 21 1,000 1,073E-03 0,01424724 ! lipid phosphorylation GO:0046834 43 21 1,000 1,073E-03 0,01417023 ! regulation of vasoconstriction GO:0019229 40 21 1,000 1,073E-03 0,01409404 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 1,073E-03 0,01401867 ! regulation of DNA binding GO:0051101 167 89 2,000 1,165E-03 0,01513755 ! protein localization in nucleus GO:0034504 192 89 2,000 1,165E-03 0,01505746 ! inactivation of MAPK activity GO:0000188 45 22 1,000 1,179E-03 0,01515436 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 1,179E-03 0,01507501 ! cellular response to starvation GO:0009267 37 22 1,000 1,179E-03 0,0149965 ! cell aging GO:0007569 48 22 1,000 1,179E-03 0,0149188 ! G1 phase GO:0051318 44 22 1,000 1,179E-03 0,01484189 ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,179E-03 0,01476578 ! gut development GO:0048565 44 22 1,000 1,179E-03 0,01469045 ! ossification GO:0001503 205 91 2,000 1,242E-03 0,01540251 ! bone development GO:0060348 206 92 2,000 1,282E-03 0,01581509 ! positive regulation of DNA replication GO:0045740 44 23 1,000 1,289E-03 0,01582328 ! regulation of DNA recombination GO:0000018 51 23 1,000 1,289E-03 0,01574416 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 1,289E-03 0,01566584 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 1,289E-03 0,01558828 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 1,322E-03 0,01591338 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 1,404E-03 0,0168135 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 1,404E-03 0,01673148 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 1,404E-03 0,01665026 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,404E-03 0,01656983 ! membrane depolarization GO:0051899 45 24 1,000 1,404E-03 0,01649016 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 1,404E-03 0,01641126 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 1,404E-03 0,01633311 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 1,524E-03 0,01764283 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 1,524E-03 0,01755961 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,524E-03 0,01747717 ! vasculogenesis GO:0001570 49 25 1,000 1,524E-03 0,0173955 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 1,524E-03 0,01731459 ! skeletal muscle tissue development GO:0007519 223 100 2,000 1,629E-03 0,01842148 GO:0060538|skeletal muscle organ development, ! initiation of viral infection GO:0019059 60 26 1,000 1,648E-03 0,01855681 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 1,648E-03 0,01847169 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 1,648E-03 0,01838735 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 1,648E-03 0,01830377 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 1,648E-03 0,01822094 ! osteoblast differentiation GO:0001649 63 26 1,000 1,648E-03 0,01813887 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 1,648E-03 0,01805753 ! negative regulation of cell development GO:0010721 83 26 1,000 1,648E-03 0,01797691 GO:0050768|negative regulation of neurogenesis, ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 1,648E-03 0,01789702 ! regulation of blood coagulation GO:0030193 46 26 1,000 1,648E-03 0,01781783 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 1,778E-03 0,01912985 ! mitochondrial membrane organization GO:0007006 60 27 1,000 1,778E-03 0,01904594 ! response to starvation GO:0042594 47 27 1,000 1,778E-03 0,01896277 ! response to toxin GO:0009636 49 27 1,000 1,778E-03 0,01888033 ! cellular response to nutrient levels GO:0031669 45 27 1,000 1,778E-03 0,01879859 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 1,911E-03 0,02012726 ! protein amino acid acylation GO:0043543 59 28 1,000 1,911E-03 0,02004087 ! vesicle docking GO:0048278 55 28 1,000 1,911E-03 0,01995523 ! base-excision repair GO:0006284 41 28 1,000 1,911E-03 0,01987031 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 1,911E-03 0,01978612 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 1,911E-03 0,01970263 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 2,05E-03 0,02104169 ! somitogenesis GO:0001756 52 29 1,000 2,05E-03 0,02095365 ! complement activation, classical pathway GO:0006958 51 30 1,000 2,193E-03 0,02232339 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 2,193E-03 0,02223077 ! regulation of B cell activation GO:0050864 55 30 1,000 2,193E-03 0,0221389 ! regulation of coagulation GO:0050818 52 30 1,000 2,193E-03 0,0220478 ! male gonad development GO:0008584 56 31 1,000 2,341E-03 0,02343669 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 2,341E-03 0,02334103 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 2,493E-03 0,02475886 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 2,493E-03 0,02465862 ! positive regulation of catabolic process GO:0009896 72 32 1,000 2,493E-03 0,02455919 ! regulation of pH GO:0006885 56 33 1,000 2,65E-03 0,02599979 ! cholesterol homeostasis GO:0042632 60 33 1,000 2,65E-03 0,02589579 GO:0055092|sterol homeostasis, ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 2,65E-03 0,02579262 ! triglyceride metabolic process GO:0006641 46 33 1,000 2,65E-03 0,02569027 ! response to ionizing radiation GO:0010212 74 33 1,000 2,65E-03 0,02558872 ! leukocyte chemotaxis GO:0030595 55 33 1,000 2,65E-03 0,02548798 GO:0060326|cell chemotaxis, ! inner ear morphogenesis GO:0042472 51 34 1,000 2,811E-03 0,02693451 ! cholesterol transport GO:0030301 62 34 1,000 2,811E-03 0,0268293 ! cell fate specification GO:0001708 56 34 1,000 2,811E-03 0,02672491 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 2,811E-03 0,02662132 ! DNA damage checkpoint GO:0000077 78 35 1,000 2,977E-03 0,02808374 ! membrane docking GO:0022406 69 35 1,000 2,977E-03 0,02797573 ! positive regulation of endocytosis GO:0045807 56 35 1,000 2,977E-03 0,02786854 ! sterol transport GO:0015918 63 35 1,000 2,977E-03 0,02776217 ! calcium-mediated signaling GO:0019722 67 35 1,000 2,977E-03 0,02765661 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 3,148E-03 0,02912902 ! embryonic organ development GO:0048568 67 36 1,000 3,148E-03 0,0290191 ! xenobiotic metabolic process GO:0006805 55 37 1,000 3,323E-03 0,0305164 ! regulation of microtubule-based process GO:0032886 86 37 1,000 3,323E-03 0,03040211 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 3,502E-03 0,03192368 ! neutral lipid metabolic process GO:0006638 54 38 1,000 3,502E-03 0,031805 GO:0006639|acylglycerol metabolic process, ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 3,502E-03 0,03168721 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 3,686E-03 0,03322715 ! carbohydrate homeostasis GO:0033500 59 39 1,000 3,686E-03 0,03310499 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 1,000 3,686E-03 0,03298373 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 3,686E-03 0,03286335 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 3,874E-03 0,03441581 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 1,000 3,874E-03 0,03429111 ! lipid homeostasis GO:0055088 75 40 1,000 3,874E-03 0,03416732 ! glycerol ether metabolic process GO:0006662 57 40 1,000 3,874E-03 0,03404441 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 4,067E-03 0,03560883 ! ear morphogenesis GO:0042471 64 42 1,000 4,264E-03 0,0372002 ! organic ether metabolic process GO:0018904 59 42 1,000 4,264E-03 0,03706781 ! regulation of leukocyte mediated immunity GO:0002703 84 42 1,000 4,264E-03 0,03693637 ! regulation of T cell differentiation GO:0045580 78 42 1,000 4,264E-03 0,03680585 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 4,264E-03 0,03667625 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 4,465E-03 0,03827324 GO:0090047|positive regulation of transcription regulator activity, ! development of primary male sexual characteristics GO:0046546 80 43 1,000 4,465E-03 0,03813942 ! segmentation GO:0035282 78 43 1,000 4,465E-03 0,03800653 ! phagocytosis GO:0006909 105 44 1,000 4,671E-03 0,03961898 ! double-strand break repair GO:0006302 85 44 1,000 4,671E-03 0,03948189 ! B cell differentiation GO:0030183 124 45 1,000 4,881E-03 0,04111443 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 4,881E-03 0,04097315 ! leukocyte migration GO:0050900 75 46 1,000 5,095E-03 0,04262527 ! positive regulation of cell cycle GO:0045787 96 48 1,000 5,536E-03 0,04615902 ! mitochondrial transport GO:0006839 94 48 1,000 5,536E-03 0,04600201 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 5,536E-03 0,04584608 ! male sex differentiation GO:0046661 93 48 1,000 5,536E-03 0,04569119 ! regulation of adaptive immune response GO:0002819 92 48 1,000 5,536E-03 0,04553735 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 5,763E-03 0,04724534 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 5,763E-03 0,04708733 ! protein homooligomerization GO:0051260 84 49 1,000 5,763E-03 0,04693038 ! activation of caspase activity GO:0006919 95 50 1,000 5,994E-03 0,04865086 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 5,994E-03 0,04848977 GO:0019724|B cell mediated immunity, ! viral infectious cycle GO:0019058 104 51 1,000 6,23E-03 0,0502275 ! negative regulation of immune system process GO:0002683 101 51 1,000 6,23E-03 0,05006228 ! histone modification GO:0016570 104 52 1,000 6,469E-03 0,05181684 ! positive regulation of growth GO:0045927 96 53 1,000 6,713E-03 0,05359304 ! inner ear development GO:0048839 89 53 1,000 6,713E-03 0,05341847 ! vesicle organization GO:0016050 127 53 1,000 6,713E-03 0,05324503 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 6,713E-03 0,05307272 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 1,000 6,713E-03 0,05290151 ! cartilage development GO:0051216 99 53 1,000 6,713E-03 0,05273141 ! activation of phospholipase C activity GO:0007202 110 54 1,000 6,961E-03 0,05450283 GO:0010863|positive regulation of phospholipase C activity, ! embryonic skeletal system development GO:0048706 101 54 1,000 6,961E-03 0,0543287 ! regulation of muscle contraction GO:0006937 94 54 1,000 6,961E-03 0,05415568 ! membrane fusion GO:0006944 122 54 1,000 6,961E-03 0,05398376 ! covalent chromatin modification GO:0016569 115 54 1,000 6,961E-03 0,05381292 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 7,213E-03 0,05558463 ! regulation of protein polymerization GO:0032271 117 55 1,000 7,213E-03 0,05540984 ! positive regulation of caspase activity GO:0043280 108 57 1,000 7,729E-03 0,05918848 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 7,729E-03 0,05900352 ! heart morphogenesis GO:0003007 105 57 1,000 7,729E-03 0,0588197 ! nucleotide-excision repair GO:0006289 91 57 1,000 7,729E-03 0,05863703 ! aging GO:0007568 112 58 1,000 7,993E-03 0,06045319 ! positive regulation of organelle organization GO:0010638 108 58 1,000 7,993E-03 0,0602666 ! positive regulation of lipase activity GO:0060193 115 58 1,000 7,993E-03 0,06008117 ! lipid modification GO:0030258 112 60 1,000 8,533E-03 0,06394589 ! regulation of endocytosis GO:0030100 104 60 1,000 8,533E-03 0,06375033 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 8,809E-03 0,06561278 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 9,089E-03 0,06749337 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 9,953E-03 0,0736849 ! ear development GO:0043583 114 66 1,000 0,01024915 0,07564552 ! gonad development GO:0008406 115 66 1,000 0,01024915 0,07541767 ! activation of MAPK activity GO:0000187 124 67 1,000 0,01054882 0,07738972 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,01054882 0,07715802 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,01085236 0,07914121 ! regulation of lipase activity GO:0060191 137 68 1,000 0,01085236 0,07890567 ! adaptive immune response GO:0002250 126 68 1,000 0,01085236 0,07867153 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! homeostasis of number of cells GO:0048872 131 69 1,000 0,01115972 0,08066037 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,01115972 0,08042243 ! activation of immune response GO:0002253 120 70 1,000 0,01147091 0,08242184 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,01147091 0,08218014 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01148254 0,08202295 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01148254 0,08178382 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01148254 0,08154608 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01148254 0,08130971 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01148254 0,08107471 ! neuron fate determination GO:0048664 7 5 0,000 0,01148254 0,08084107 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01148254 0,08060877 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01148254 0,0803778 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01148254 0,08014814 ! polyol transport GO:0015791 12 5 0,000 0,01148254 0,0799198 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01148254 0,07969276 ! response to superoxide GO:0000303 10 5 0,000 0,01148254 0,079467 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01148254 0,07924252 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01148254 0,0790193 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01148254 0,07879733 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01148254 0,07857661 ! female meiosis GO:0007143 10 5 0,000 0,01148254 0,07835712 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01148254 0,07813886 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01148254 0,07792181 ! hypothalamus development GO:0021854 9 5 0,000 0,01148254 0,07770596 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01148254 0,0774913 ! cobalt ion transport GO:0006824 11 5 0,000 0,01148254 0,07727783 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01148254 0,07706552 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01148254 0,07685439 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01148254 0,0766444 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01148254 0,07643556 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01148254 0,07622785 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01148254 0,07602128 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01148254 0,07581581 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01148254 0,07561146 ! transposition GO:0032196 9 5 0,000 0,01148254 0,0754082 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01148254 0,07520603 ! negative chemotaxis GO:0050919 16 5 0,000 0,01148254 0,07500495 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01148254 0,07480493 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01148254 0,07460599 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01148254 0,07440809 ! behavioral response to pain GO:0048266 10 5 0,000 0,01148254 0,07421124 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01148254 0,07401544 ! Notch receptor processing GO:0007220 11 5 0,000 0,01148254 0,07382066 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01148254 0,0736269 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01148254 0,07343416 ! micturition GO:0060073 9 5 0,000 0,01148254 0,07324243 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01148254 0,07305169 ! copulation GO:0007620 9 5 0,000 0,01148254 0,07286195 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01148254 0,07267319 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01148254 0,0724854 ! bioluminescence GO:0008218 9 5 0,000 0,01148254 0,07229858 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01148254 0,07211273 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01148254 0,07192782 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01148254 0,07174386 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01148254 0,07156084 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01148254 0,07137875 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01148254 0,07119759 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01148254 0,07101734 ! grooming behavior GO:0007625 6 5 0,000 0,01148254 0,07083801 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01148254 0,07065957 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01148254 0,07048204 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01148254 0,07030539 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01148254 0,07012963 ! response to protozoan GO:0001562 13 5 0,000 0,01148254 0,06995474 ! lymph vessel development GO:0001945 10 5 0,000 0,01148254 0,06978072 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01148254 0,06960757 ! endochondral ossification GO:0001958 17 5 0,000 0,01148254 0,06943527 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01148254 0,06926383 ! single strand break repair GO:0000012 8 5 0,000 0,01148254 0,06909323 ! parathyroid gland development GO:0060017 14 5 0,000 0,01148254 0,06892347 ! anagen GO:0042640 7 5 0,000 0,01148254 0,06875454 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01148254 0,06858643 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01148254 0,06841915 ! cytokine secretion GO:0050663 15 5 0,000 0,01148254 0,06825268 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01148254 0,06808702 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01148254 0,06792216 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01148254 0,06775809 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01148254 0,06759482 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01148254 0,06743233 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01148254 0,06727062 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01148254 0,06710969 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01148254 0,06694952 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01148254 0,06679012 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01148254 0,06663147 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01148254 0,06647358 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01148254 0,06631643 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01148254 0,06616002 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01148254 0,06600435 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01148254 0,06584941 ! microvillus organization GO:0032528 8 5 0,000 0,01148254 0,0656952 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01148254 0,06554171 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01148254 0,06538893 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01148254 0,06523686 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01148254 0,0650855 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01148254 0,06493484 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01148254 0,06478487 ! polyol catabolic process GO:0046174 9 5 0,000 0,01148254 0,0646356 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01148254 0,06448701 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01148254 0,06433911 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01148254 0,06419188 ! muscle cell migration GO:0014812 8 5 0,000 0,01148254 0,06404532 ! mitochondrial fission GO:0000266 8 5 0,000 0,01148254 0,06389943 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01148254 0,06375421 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01148254 0,06360964 ! mRNA transcription GO:0009299 10 5 0,000 0,01148254 0,06346573 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01148254 0,06332246 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01148254 0,06317984 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01148254 0,06303787 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01148254 0,06289653 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01148254 0,06275582 ! monocyte activation GO:0042117 10 5 0,000 0,01148254 0,06261574 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01148254 0,06247628 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01148254 0,06233745 ! response to food GO:0032094 6 5 0,000 0,01148254 0,06219923 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01148254 0,06206162 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01148254 0,06192461 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01148254 0,06178822 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01148254 0,06165242 ! forebrain neuron development GO:0021884 13 5 0,000 0,01148254 0,06151722 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01148254 0,06138261 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01148254 0,06124858 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01148254 0,06111514 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01148254 0,06098228 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01148254 0,06085 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01148254 0,06071829 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01148254 0,06058715 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01148254 0,06045657 ! lipid glycosylation GO:0030259 7 5 0,000 0,01148254 0,06032656 ! nucleobase transport GO:0015851 6 5 0,000 0,01148254 0,0601971 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01148254 0,0600682 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01148254 0,05993985 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01148254 0,05981205 ! basic amino acid transport GO:0015802 12 5 0,000 0,01148254 0,05968479 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01148254 0,05955807 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01148254 0,05943189 ! actin nucleation GO:0045010 11 5 0,000 0,01148254 0,05930624 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01148254 0,05918112 ! depurination GO:0045007 5 5 0,000 0,01148254 0,05905653 ! depyrimidination GO:0045008 10 5 0,000 0,01148254 0,05893246 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01148254 0,05880891 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01148254 0,05868588 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01148254 0,05856336 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01148254 0,05844136 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01148254 0,05831986 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01148254 0,05819886 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01148254 0,05807837 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01148254 0,05795837 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01148254 0,05783887 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01148254 0,05771986 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01148254 0,05760134 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01148254 0,0574833 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01148254 0,05736575 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01148254 0,05724867 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01148254 0,05713208 ! response to arsenic GO:0046685 11 5 0,000 0,01148254 0,05701596 ! mast cell degranulation GO:0043303 7 5 0,000 0,01148254 0,05690031 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01148254 0,05678512 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01148254 0,05667041 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01148254 0,05655615 ! response to mercury ion GO:0046689 8 5 0,000 0,01148254 0,05644236 ! response to cadmium ion GO:0046686 7 5 0,000 0,01148254 0,05632902 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01148254 0,05621613 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01148254 0,0561037 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01148254 0,05599172 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01148254 0,05588018 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01148254 0,05576909 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01148254 0,05565843 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01148254 0,05554822 ! decidualization GO:0046697 11 5 0,000 0,01148254 0,05543844 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01148254 0,05532909 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01148254 0,05522018 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01148254 0,05511169 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01148254 0,05500363 ! embryonic cleavage GO:0040016 6 5 0,000 0,01148254 0,05489599 ! peroxisome fission GO:0016559 5 5 0,000 0,01148254 0,05478877 ! histone demethylation GO:0016577 13 5 0,000 0,01148254 0,05468197 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01148254 0,05457558 ! mitotic recombination GO:0006312 9 5 0,000 0,01148254 0,05446961 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01148254 0,05436405 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01148254 0,0542589 ! metaphase plate congression GO:0051310 7 5 0,000 0,01148254 0,05415415 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01148254 0,05404981 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01148254 0,05394587 ! enteric nervous system development GO:0048484 8 5 0,000 0,01148254 0,05384232 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01148254 0,05373918 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01148254 0,05363643 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01148254 0,05353407 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01148254 0,0534321 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01148254 0,05333051 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01148254 0,05322932 ! B cell homeostasis GO:0001782 13 5 0,000 0,01148254 0,0531285 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01148254 0,05302807 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01148254 0,05292802 ! metaphase GO:0051323 11 5 0,000 0,01148254 0,05282834 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01148254 0,05272904 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01148254 0,05263011 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01148254 0,05253156 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01148254 0,05243337 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01148254 0,05233554 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01148254 0,05223808 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01148254 0,05214099 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01148254 0,05204425 ! response to redox state GO:0051775 6 5 0,000 0,01148254 0,05194787 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01148254 0,05185185 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01148254 0,05175618 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01148254 0,05166087 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01148254 0,0515659 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01148254 0,05147129 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01148254 0,05137702 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01148254 0,05128309 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01148254 0,05118951 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01148254 0,05109627 ! striatum development GO:0021756 14 5 0,000 0,01148254 0,05100336 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01148254 0,0509108 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01148254 0,05081857 ! glial cell migration GO:0008347 10 5 0,000 0,01148254 0,05072667 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01148254 0,05063511 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01148254 0,05054387 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01148254 0,05045297 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01148254 0,05036239 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01148254 0,05027213 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01148254 0,0501822 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01148254 0,05009259 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01148254 0,0500033 ! neuroprotection GO:0043526 8 5 0,000 0,01148254 0,04991432 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01148254 0,04982567 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01148254 0,04973732 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01148254 0,04964929 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01148254 0,04956157 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01148254 0,04947416 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01148254 0,04938706 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01148254 0,04930026 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01148254 0,04921377 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01148254 0,04912758 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01148254 0,0490417 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01148254 0,04895611 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01148254 0,04887082 ! spindle assembly GO:0051225 6 5 0,000 0,01148254 0,04878583 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01148254 0,04870113 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01148254 0,04861673 ! protein palmitoylation GO:0018345 12 5 0,000 0,01148254 0,04853261 ! drug metabolic process GO:0017144 7 5 0,000 0,01148254 0,04844879 ! stem cell division GO:0017145 11 5 0,000 0,01148254 0,04836526 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01148254 0,04828201 ! organ regeneration GO:0031100 7 5 0,000 0,01148254 0,04819906 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01148254 0,04811638 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01148254 0,04803399 ! appendage morphogenesis GO:0035107 150 72 1,000 0,01210465 0,05054985 GO:0035108|limb morphogenesis, ! B cell activation GO:0042113 179 72 1,000 0,01210465 0,05046359 ! appendage development GO:0048736 151 73 1,000 0,01242717 0,0517199 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 1,000 0,01242717 0,05163194 ! regulation of immune effector process GO:0002697 156 73 1,000 0,01242717 0,05154428 ! acute inflammatory response GO:0002526 118 74 1,000 0,01275344 0,05280787 ! regulation of caspase activity GO:0043281 136 74 1,000 0,01275344 0,05271852 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01308342 0,05399122 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 1,000 0,01308342 0,05390018 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,01308342 0,05380943 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01375449 0,05647434 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,01375449 0,05637958 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,01375449 0,05628514 ! regulation of catabolic process GO:0009894 173 77 1,000 0,01375449 0,05619102 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01376337 0,05613342 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01376337 0,05603987 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01376337 0,05594662 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01376337 0,05585369 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01376337 0,05576106 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01376337 0,05566874 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01376337 0,05557673 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01376337 0,05548502 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01376337 0,05539361 ! response to oxygen radical GO:0000305 11 6 0,000 0,01376337 0,0553025 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01376337 0,05521169 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01376337 0,05512118 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01376337 0,05503096 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01376337 0,05494104 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01376337 0,05485142 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01376337 0,05476208 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01376337 0,05467304 ! forebrain regionalization GO:0021871 9 6 0,000 0,01376337 0,05458428 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01376337 0,05449582 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01376337 0,05440764 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01376337 0,05431974 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01376337 0,05423213 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01376337 0,0541448 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01376337 0,05405775 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01376337 0,05397098 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01376337 0,05388449 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01376337 0,05379827 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01376337 0,05371233 ! malate metabolic process GO:0006108 13 6 0,000 0,01376337 0,05362667 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01376337 0,05354127 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01376337 0,05345615 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01376337 0,0533713 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01376337 0,05328672 ! protein refolding GO:0042026 15 6 0,000 0,01376337 0,0532024 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01376337 0,05311836 ! mating behavior GO:0007617 7 6 0,000 0,01376337 0,05303457 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01376337 0,05295105 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01376337 0,0528678 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01376337 0,0527848 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01376337 0,05270207 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01376337 0,05261959 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01376337 0,05253737 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01376337 0,05245541 ! toxin metabolic process GO:0009404 11 6 0,000 0,01376337 0,05237371 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01376337 0,05229225 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01376337 0,05221105 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01376337 0,05213011 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01376337 0,05204941 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01376337 0,05196896 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01376337 0,05188876 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01376337 0,05180881 ! thymic T cell selection GO:0045061 16 6 0,000 0,01376337 0,05172911 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01376337 0,05164965 ! protein lipoylation GO:0009249 10 6 0,000 0,01376337 0,05157043 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01376337 0,05149145 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01376337 0,05141272 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01376337 0,05133423 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01376337 0,05125597 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01376337 0,05117796 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01376337 0,05110018 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01376337 0,05102264 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01376337 0,05094533 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01376337 0,05086826 ! hyperosmotic response GO:0006972 10 6 0,000 0,01376337 0,05079142 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01376337 0,05071481 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01376337 0,05063843 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01376337 0,05056228 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01376337 0,05048637 ! urea metabolic process GO:0019627 7 6 0,000 0,01376337 0,05041067 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01376337 0,05033521 ! neutrophil activation GO:0042119 7 6 0,000 0,01376337 0,05025997 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01376337 0,05018495 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01376337 0,05011016 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01376337 0,05003559 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01376337 0,04996125 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01376337 0,04988712 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01376337 0,04981321 ! neuron apoptosis GO:0051402 15 6 0,000 0,01376337 0,04973953 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01376337 0,04966605 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01376337 0,0495928 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01376337 0,04951976 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01376337 0,04944694 ! carnitine transport GO:0015879 10 6 0,000 0,01376337 0,04937433 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01376337 0,04930193 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01376337 0,04922975 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01376337 0,04915778 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01376337 0,04908601 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01376337 0,04901446 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01376337 0,04894311 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01376337 0,04887198 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01376337 0,04880104 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01376337 0,04873032 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01376337 0,0486598 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01376337 0,04858948 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01376337 0,04851936 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01376337 0,04844945 ! response to UV-C GO:0010225 14 6 0,000 0,01376337 0,04837974 ! astrocyte development GO:0014002 16 6 0,000 0,01376337 0,04831023 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01376337 0,04824092 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01376337 0,0481718 ! interaction with symbiont GO:0051702 14 6 0,000 0,01376337 0,04810289 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01376337 0,04803417 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01376337 0,04796565 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01376337 0,04789732 ! response to copper ion GO:0046688 10 6 0,000 0,01376337 0,04782919 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01376337 0,04776125 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01376337 0,0476935 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01376337 0,04762595 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01376337 0,04755858 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01376337 0,04749141 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01376337 0,04742443 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01376337 0,04735763 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01376337 0,04729103 ! hair follicle maturation GO:0048820 8 6 0,000 0,01376337 0,04722461 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01376337 0,04715837 ! Schwann cell development GO:0014044 15 6 0,000 0,01376337 0,04709232 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01376337 0,04702646 ! response to pheromone GO:0019236 6 6 0,000 0,01376337 0,04696078 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01376337 0,04689528 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01376337 0,04682997 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01376337 0,04676484 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01376337 0,04669989 ! subpallium development GO:0021544 15 6 0,000 0,01376337 0,04663512 ! neural tube patterning GO:0021532 8 6 0,000 0,01376337 0,04657053 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01376337 0,04650611 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01376337 0,04644188 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01376337 0,04637782 ! G2 phase GO:0051319 16 6 0,000 0,01376337 0,04631394 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01376337 0,04625023 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01376337 0,0461867 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01376337 0,04612335 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01376337 0,04606016 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01376337 0,04599715 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01376337 0,04593432 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01376337 0,04587165 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01376337 0,04580915 ! receptor internalization GO:0031623 11 6 0,000 0,01376337 0,04574683 ! plasminogen activation GO:0031639 9 6 0,000 0,01376337 0,04568467 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01376337 0,04562269 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01376337 0,04556087 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01376337 0,04549921 ! protein deubiquitination GO:0016579 16 6 0,000 0,01376337 0,04543773 ! protein destabilization GO:0031648 9 6 0,000 0,01376337 0,04537641 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01376337 0,04531525 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01376337 0,04525427 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01376337 0,04519344 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01376337 0,04513278 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01376337 0,04507228 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01376337 0,04501194 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01376337 0,04495176 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01376337 0,04489175 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01376337 0,04483189 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01376337 0,0447722 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01376337 0,04471266 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01376337 0,04465328 ! neural plate development GO:0001840 9 6 0,000 0,01376337 0,04459406 ! catecholamine transport GO:0051937 9 6 0,000 0,01376337 0,04453499 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01376337 0,04447608 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01376337 0,04441733 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01376337 0,04435873 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01376337 0,04430029 ! maternal placenta development GO:0001893 12 6 0,000 0,01376337 0,044242 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01376337 0,04418386 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01376337 0,04412588 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01376337 0,04406805 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01376337 0,04401037 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01376337 0,04395284 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01376337 0,04389546 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01376337 0,04383823 GO:0055081|anion homeostasis, ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,01478857 0,04704228 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,01514051 0,04809917 ! response to drug GO:0042493 149 83 1,000 0,01585516 0,0503041 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,01585516 0,05023886 GO:0045937|positive regulation of phosphate metabolic process, ! tRNA transcription GO:0009304 17 7 0,000 0,016039 0,05075555 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,016039 0,05068989 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,016039 0,0506244 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,016039 0,05055908 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,016039 0,05049393 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,016039 0,05042894 ! sleep GO:0030431 16 7 0,000 0,016039 0,05036412 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,016039 0,05029947 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,016039 0,05023498 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,016039 0,05017066 ! prostate gland development GO:0030850 14 7 0,000 0,016039 0,05010651 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,016039 0,05004251 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,016039 0,04997868 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,016039 0,04991502 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,016039 0,04985151 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,016039 0,04978817 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,016039 0,04972498 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,016039 0,04966196 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,016039 0,0495991 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,016039 0,04953639 ! glycolipid transport GO:0046836 11 7 0,000 0,016039 0,04947385 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,016039 0,04941146 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,016039 0,04934923 ! neuron adhesion GO:0007158 14 7 0,000 0,016039 0,04928715 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,016039 0,04922524 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,016039 0,04916347 ! mRNA stabilization GO:0048255 18 7 0,000 0,016039 0,04910186 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,016039 0,04904041 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,016039 0,04897911 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,016039 0,04891796 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,016039 0,04885697 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,016039 0,04879612 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,016039 0,04873543 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,016039 0,04867489 ! lipoprotein transport GO:0042953 14 7 0,000 0,016039 0,0486145 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,016039 0,04855426 ! rhythmic behavior GO:0007622 17 7 0,000 0,016039 0,04849417 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,016039 0,04843422 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,016039 0,04837443 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,016039 0,04831478 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,016039 0,04825528 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,016039 0,04819593 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,016039 0,04813672 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,016039 0,04807765 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,016039 0,04801873 ! mechanosensory behavior GO:0007638 16 7 0,000 0,016039 0,04795996 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,016039 0,04790133 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,016039 0,04784284 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,016039 0,0477845 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,016039 0,04772629 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,016039 0,04766823 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,016039 0,04761031 ! spinal cord patterning GO:0021511 14 7 0,000 0,016039 0,04755253 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,016039 0,04749489 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,016039 0,04743739 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,016039 0,04738003 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,016039 0,04732281 ! adrenal gland development GO:0030325 17 7 0,000 0,016039 0,04726573 ! cysteine metabolic process GO:0006534 13 7 0,000 0,016039 0,04720878 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,016039 0,04715197 ! ovulation GO:0030728 10 7 0,000 0,016039 0,0470953 ! adenohypophysis development GO:0021984 11 7 0,000 0,016039 0,04703876 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,016039 0,04698236 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,016039 0,04692609 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 21 7 0,000 0,016039 0,04686996 ! proline biosynthetic process GO:0006561 10 7 0,000 0,016039 0,04681396 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,016039 0,0467581 ! thyroid hormone generation GO:0006590 13 7 0,000 0,016039 0,04670237 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,016039 0,04664677 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,016039 0,04659131 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,016039 0,04653597 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,016039 0,04648077 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,016039 0,0464257 ! galactose metabolic process GO:0006012 13 7 0,000 0,016039 0,04637075 ! response to dietary excess GO:0002021 8 7 0,000 0,016039 0,04631594 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,016039 0,04626126 ! intracellular pH reduction GO:0051452 13 7 0,000 0,016039 0,04620671 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,016039 0,04615228 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,016039 0,04609799 ! organ growth GO:0035265 15 7 0,000 0,016039 0,04604382 ! nucleoside transport GO:0015858 11 7 0,000 0,016039 0,04598977 ! nucleoside salvage GO:0043174 11 7 0,000 0,016039 0,04593586 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,016039 0,04588207 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,016039 0,04582841 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,016039 0,04577487 ! parturition GO:0007567 16 7 0,000 0,016039 0,04572146 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,016039 0,04566817 ! rRNA modification GO:0000154 14 7 0,000 0,016039 0,045615 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,016039 0,04556196 ! spindle checkpoint GO:0031577 16 7 0,000 0,016039 0,04550904 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,016039 0,04545625 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,016039 0,04540358 ! monocyte differentiation GO:0030224 16 7 0,000 0,016039 0,04535103 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,016039 0,0452986 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,016039 0,04524629 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,016039 0,0451941 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,016039 0,04514204 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,016039 0,04509009 ! fibrinolysis GO:0042730 11 7 0,000 0,016039 0,04503826 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,016039 0,04498655 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,016039 0,04493496 ! eating behavior GO:0042755 8 7 0,000 0,016039 0,04488349 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,016039 0,04483214 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,016039 0,0447809 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,016039 0,04472978 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,016039 0,04467878 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,016039 0,04462789 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,016039 0,04457712 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,016039 0,04452646 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,016039 0,04447592 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,016039 0,0444255 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,016039 0,04437518 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,016039 0,04432499 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,016039 0,0442749 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,016039 0,04422493 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,016039 0,04417507 ! histone ubiquitination GO:0016574 9 7 0,000 0,016039 0,04412532 ! regulation of meiosis GO:0040020 12 7 0,000 0,016039 0,04407569 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,016039 0,04402617 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,016039 0,04397675 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,016039 0,04392745 ! membrane to membrane docking GO:0022614 14 7 0,000 0,016039 0,04387826 ! transcription termination GO:0006353 14 7 0,000 0,016039 0,04382918 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,016039 0,04378021 ! anaphase GO:0051322 18 7 0,000 0,016039 0,04373135 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,016039 0,0436826 ! axonal fasciculation GO:0007413 19 7 0,000 0,016039 0,04363395 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,016039 0,04358541 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,016039 0,04353699 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,016039 0,04348867 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,016039 0,04344045 ! diuresis GO:0030146 12 7 0,000 0,016039 0,04339235 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,016039 0,04334434 ! thiamin metabolic process GO:0006772 7 7 0,000 0,016039 0,04329645 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,016039 0,04324866 ! antibiotic transport GO:0042891 9 7 0,000 0,016039 0,04320098 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,016039 0,0431534 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,016039 0,04310593 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,016039 0,04305856 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,016039 0,04301129 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,016039 0,04296413 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,016039 0,04291707 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,016039 0,04287012 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,016039 0,04282327 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,016039 0,04277651 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,016039 0,04272987 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,016039 0,04268332 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,016039 0,04263687 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,016039 0,04259053 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,016039 0,04254429 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,016039 0,04249814 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,016039 0,0424521 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,016039 0,04240616 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,016039 0,04236031 ! muscle adaptation GO:0043500 13 7 0,000 0,016039 0,04231457 ! embryonic heart tube development GO:0035050 14 7 0,000 0,016039 0,04226892 ! retina homeostasis GO:0001895 12 7 0,000 0,016039 0,04222337 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,016039 0,04217792 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,016039 0,04213257 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,016039 0,04208731 ! mitochondrion organization GO:0007005 159 87 1,000 0,01732704 0,0454184 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01830945 0,04794211 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01830945 0,04789078 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01830945 0,04783956 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01830945 0,04778845 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01830945 0,04773744 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01830945 0,04768655 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01830945 0,04763577 ! male meiosis GO:0007140 9 8 0,000 0,01830945 0,04758509 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01830945 0,04753452 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01830945 0,04748406 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01830945 0,04743371 ! meiotic prophase I GO:0007128 14 8 0,000 0,01830945 0,04738346 ! response to zinc ion GO:0010043 12 8 0,000 0,01830945 0,04733332 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01830945 0,04728328 ! oligopeptide transport GO:0006857 16 8 0,000 0,01830945 0,04723335 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01830945 0,04718353 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01830945 0,04713381 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01830945 0,04708419 ! signal peptide processing GO:0006465 12 8 0,000 0,01830945 0,04703468 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01830945 0,04698528 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01830945 0,04693598 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01830945 0,04688678 ! succinate metabolic process GO:0006105 17 8 0,000 0,01830945 0,04683768 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01830945 0,04678869 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01830945 0,0467398 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01830945 0,04669101 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01830945 0,04664232 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01830945 0,04659373 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01830945 0,04654525 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01830945 0,04649687 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01830945 0,04644858 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01830945 0,0464004 ! reflex GO:0060004 17 8 0,000 0,01830945 0,04635232 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01830945 0,04630433 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01830945 0,04625645 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01830945 0,04620866 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01830945 0,04616097 ! pigment granule organization GO:0048753 17 8 0,000 0,01830945 0,04611339 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01830945 0,0460659 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01830945 0,0460185 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01830945 0,04597121 ! histidine catabolic process GO:0006548 10 8 0,000 0,01830945 0,04592401 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01830945 0,04587691 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01830945 0,0458299 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01830945 0,04578299 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01830945 0,04573618 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01830945 0,04568946 ! melanin metabolic process GO:0006582 17 8 0,000 0,01830945 0,04564284 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01830945 0,04559631 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01830945 0,04554988 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01830945 0,04550354 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01830945 0,0454573 ! macrophage activation GO:0042116 13 8 0,000 0,01830945 0,04541115 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01830945 0,0453651 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01830945 0,04531913 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01830945 0,04527326 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01830945 0,04522749 ! purine salvage GO:0043101 12 8 0,000 0,01830945 0,0451818 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01830945 0,04513621 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01830945 0,04509071 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01830945 0,0450453 ! osteoblast development GO:0002076 17 8 0,000 0,01830945 0,04499998 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01830945 0,04495476 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01830945 0,04490962 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01830945 0,04486458 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01830945 0,04481962 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01830945 0,04477476 ! response to UV-B GO:0010224 17 8 0,000 0,01830945 0,04472998 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01830945 0,0446853 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01830945 0,0446407 ! intermediate filament organization GO:0045109 12 8 0,000 0,01830945 0,0445962 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01830945 0,04455178 ! cellular extravasation GO:0045123 13 8 0,000 0,01830945 0,04450745 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01830945 0,04446321 ! response to antibiotic GO:0046677 11 8 0,000 0,01830945 0,04441905 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01830945 0,04437498 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01830945 0,04433101 ! DNA topological change GO:0006265 12 8 0,000 0,01830945 0,04428711 ! response to tropane GO:0014073 15 8 0,000 0,01830945 0,04424331 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,01830945 0,04419959 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01830945 0,04415596 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01830945 0,04411241 ! mast cell activation GO:0045576 14 8 0,000 0,01830945 0,04406895 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01830945 0,04402558 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01830945 0,04398229 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01830945 0,04393908 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01830945 0,04389596 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01830945 0,04385293 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01830945 0,04380998 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01830945 0,04376711 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01830945 0,04372433 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01830945 0,04368163 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01830945 0,04363901 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01830945 0,04359648 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01830945 0,04355403 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01830945 0,04351166 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01830945 0,04346937 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01830945 0,04342717 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01830945 0,04338505 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01830945 0,04334301 ! hormone catabolic process GO:0042447 17 8 0,000 0,01830945 0,04330105 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01830945 0,04325917 GO:0046479|glycosphingolipid catabolic process, ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01830945 0,04321738 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01830945 0,04317566 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01830945 0,04313403 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01830945 0,04309247 ! adult feeding behavior GO:0008343 10 8 0,000 0,01830945 0,043051 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01830945 0,0430096 ! ATP catabolic process GO:0006200 11 8 0,000 0,01830945 0,04296829 ! blastocyst growth GO:0001832 19 8 0,000 0,01830945 0,04292705 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01830945 0,04288589 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01830945 0,04284481 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01830945 0,04280381 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01830945 0,04276289 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01830945 0,04272205 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01830945 0,04268128 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01830945 0,0426406 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01830945 0,04259999 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01830945 0,04255945 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01830945 0,042519 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01830945 0,04247862 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01830945 0,04243832 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01830945 0,04239809 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01830945 0,04235794 ! protein prenylation GO:0018342 21 8 0,000 0,01830945 0,04231787 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01830945 0,04227787 ! gland development GO:0048732 220 91 1,000 0,01885472 0,04349583 ! regulation of membrane potential GO:0042391 179 94 1,000 0,02003643 0,04617831 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,02043709 0,04705732 ! axon extension GO:0048675 16 9 0,000 0,02057472 0,0473296 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02057472 0,04728508 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02057472 0,04724064 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02057472 0,04719628 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02057472 0,04715201 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02057472 0,04710782 ! reproductive behavior GO:0019098 22 9 0,000 0,02057472 0,04706371 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02057472 0,04701968 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02057472 0,04697574 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02057472 0,04693188 ! UTP metabolic process GO:0046051 10 9 0,000 0,02057472 0,0468881 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02057472 0,0468444 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02057472 0,04680078 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02057472 0,04675725 ! artery development GO:0060840 25 9 0,000 0,02057472 0,04671379 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02057472 0,04667042 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02057472 0,04662712 ! equilibrioception GO:0050957 20 9 0,000 0,02057472 0,04658391 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02057472 0,04654078 ! chemosensory behavior GO:0007635 21 9 0,000 0,02057472 0,04649772 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02057472 0,04645475 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02057472 0,04641185 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02057472 0,04636904 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02057472 0,0463263 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02057472 0,04628365 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02057472 0,04624107 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02057472 0,04619856 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02057472 0,04615614 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02057472 0,0461138 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02057472 0,04607153 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02057472 0,04602934 ! protein targeting to ER GO:0045047 25 9 0,000 0,02057472 0,04598723 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02057472 0,04594519 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02057472 0,04590323 ! T cell selection GO:0045058 27 9 0,000 0,02057472 0,04586135 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02057472 0,04581954 ! glycine catabolic process GO:0006546 15 9 0,000 0,02057472 0,04577781 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02057472 0,04573616 ! endosome organization GO:0007032 20 9 0,000 0,02057472 0,04569458 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02057472 0,04565308 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02057472 0,04561165 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02057472 0,0455703 ! mannose metabolic process GO:0006013 13 9 0,000 0,02057472 0,04552902 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02057472 0,04548782 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02057472 0,04544669 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02057472 0,04540564 ! receptor clustering GO:0043113 20 9 0,000 0,02057472 0,04536466 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02057472 0,04532375 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02057472 0,04528292 ! retinol metabolic process GO:0042572 20 9 0,000 0,02057472 0,04524216 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02057472 0,04520147 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02057472 0,04516086 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02057472 0,04512032 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02057472 0,04507986 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02057472 0,04503946 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02057472 0,04499914 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02057472 0,04495889 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02057472 0,04491871 ! response to amine stimulus GO:0014075 13 9 0,000 0,02057472 0,04487861 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02057472 0,04483857 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02057472 0,04479861 ! erythrocyte development GO:0048821 17 9 0,000 0,02057472 0,04475872 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02057472 0,0447189 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02057472 0,04467915 ! renal water homeostasis GO:0003091 15 9 0,000 0,02057472 0,04463947 ! postreplication repair GO:0006301 25 9 0,000 0,02057472 0,04459986 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02057472 0,04456032 ! icosanoid secretion GO:0032309 15 9 0,000 0,02057472 0,04452085 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02057472 0,04448145 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02057472 0,04444212 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02057472 0,04440286 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02057472 0,04436367 ! sterol catabolic process GO:0016127 14 9 0,000 0,02057472 0,04432455 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02057472 0,0442855 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02057472 0,04424651 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02057472 0,0442076 ! S phase GO:0051320 10 9 0,000 0,02057472 0,04416875 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02057472 0,04412997 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02057472 0,04409126 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02057472 0,04405262 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02057472 0,04401404 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02057472 0,04397554 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02057472 0,0439371 ! purine base metabolic process GO:0006144 25 9 0,000 0,02057472 0,04389872 ! pigment granule transport GO:0051904 17 9 0,000 0,02057472 0,04386042 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02057472 0,04382218 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02057472 0,04378401 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02057472 0,0437459 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02057472 0,04370786 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02057472 0,04366989 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02057472 0,04363198 ! mitochondrion localization GO:0051646 18 9 0,000 0,02057472 0,04359414 ! sex differentiation GO:0007548 171 96 1,000 0,0208411 0,04412029 ! regulation of T cell activation GO:0050863 175 96 1,000 0,0208411 0,04408209 ! positive regulation of immune response GO:0050778 175 100 1,000 0,02249027 0,04752919 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02283483 0,04821562 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02283483 0,04817399 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02283483 0,04813242 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02283483 0,04809093 ! associative learning GO:0008306 21 10 0,000 0,02283483 0,04804951 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02283483 0,04800816 ! phosphate transport GO:0006817 24 10 0,000 0,02283483 0,04796688 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02283483 0,04792567 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02283483 0,04788453 ! CTP metabolic process GO:0046036 11 10 0,000 0,02283483 0,04784346 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02283483 0,04780247 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02283483 0,04776154 ! GTP metabolic process GO:0046039 11 10 0,000 0,02283483 0,04772068 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02283483 0,0476799 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02283483 0,04763918 ! social behavior GO:0035176 29 10 0,000 0,02283483 0,04759853 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02283483 0,04755795 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02283483 0,04751744 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02283483 0,047477 ! androgen metabolic process GO:0008209 17 10 0,000 0,02283483 0,04743663 ! phospholipid efflux GO:0033700 19 10 0,000 0,02283483 0,04739633 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02283483 0,04735609 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02283483 0,04731593 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02283483 0,04727583 ! lung alveolus development GO:0048286 26 10 0,000 0,02283483 0,0472358 ! pathogenesis GO:0009405 17 10 0,000 0,02283483 0,04719584 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02283483 0,04715594 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02283483 0,04711611 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02283483 0,04707635 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02283483 0,04703666 ! endoderm development GO:0007492 18 10 0,000 0,02283483 0,04699703 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02283483 0,04695747 ! arginine catabolic process GO:0006527 17 10 0,000 0,02283483 0,04691798 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02283483 0,04687855 ! proline metabolic process GO:0006560 13 10 0,000 0,02283483 0,04683919 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02283483 0,0467999 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02283483 0,04676067 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02283483 0,04672151 ! V(D)J recombination GO:0033151 34 10 0,000 0,02283483 0,04668241 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02283483 0,04664338 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02283483 0,04660441 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02283483 0,04656551 ! B cell proliferation GO:0042100 19 10 0,000 0,02283483 0,04652667 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02283483 0,0464879 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02283483 0,04644919 ! multicellular organism growth GO:0035264 19 10 0,000 0,02283483 0,04641055 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02283483 0,04637197 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02283483 0,04633345 ! ruffle organization GO:0031529 17 10 0,000 0,02283483 0,046295 ! epithelial cell development GO:0002064 21 10 0,000 0,02283483 0,04625662 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02283483 0,04621829 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02283483 0,04618003 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02283483 0,04614183 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02283483 0,0461037 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02283483 0,04606563 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02283483 0,04602762 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,02283483 0,04598968 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02283483 0,04595179 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02283483 0,04591397 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02283483 0,04587622 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02283483 0,04583852 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02283483 0,04580089 ! segment specification GO:0007379 15 10 0,000 0,02283483 0,04576331 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02283483 0,0457258 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02283483 0,04568835 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02283483 0,04565096 ! response to dsRNA GO:0043331 23 10 0,000 0,02283483 0,04561364 ! DNA ligation GO:0006266 18 10 0,000 0,02283483 0,04557637 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02283483 0,04553917 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02283483 0,04550202 ! melanosome localization GO:0032400 16 10 0,000 0,02283483 0,04546494 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02283483 0,04542791 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02283483 0,04539095 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02283483 0,04535405 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02283483 0,0453172 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02283483 0,04528042 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02283483 0,0452437 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02283483 0,04520703 ! protein sumoylation GO:0016925 17 10 0,000 0,02283483 0,04517043 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02283483 0,04513388 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02283483 0,0450974 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02283483 0,04506097 ! salivary gland development GO:0007431 28 10 0,000 0,02283483 0,0450246 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02283483 0,04498829 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02283483 0,04495204 ! midbrain development GO:0030901 14 10 0,000 0,02283483 0,04491584 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02283483 0,04487971 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02283483 0,04484363 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02283483 0,04480761 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02283483 0,04477165 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02283483 0,04473575 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02283483 0,0446999 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02283483 0,04466411 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02283483 0,04462838 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02283483 0,04459271 ! detection of calcium ion GO:0005513 24 10 0,000 0,02283483 0,04455709 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02283483 0,04452153 ! blastocyst formation GO:0001825 18 10 0,000 0,02283483 0,04448603 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02283483 0,04445058 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02283483 0,04441519 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02283483 0,04437986 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02283483 0,04434458 ! response to nicotine GO:0035094 20 10 0,000 0,02283483 0,04430936 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02508978 0,04864629 ! respiratory burst GO:0045730 17 11 0,000 0,02508978 0,04860772 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02508978 0,0485692 ! neuron fate specification GO:0048665 18 11 0,000 0,02508978 0,04853075 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02508978 0,04849235 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02508978 0,04845402 ! thyroid gland development GO:0030878 26 11 0,000 0,02508978 0,04841574 ! synapsis GO:0007129 14 11 0,000 0,02508978 0,04837753 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02508978 0,04833938 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02508978 0,04830129 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02508978 0,04826325 ! response to pain GO:0048265 27 11 0,000 0,02508978 0,04822528 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02508978 0,04818737 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02508978 0,04814951 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02508978 0,04811172 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02508978 0,04807399 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02508978 0,04803631 ! bone resorption GO:0045453 16 11 0,000 0,02508978 0,04799869 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02508978 0,04796114 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02508978 0,04792364 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02508978 0,0478862 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02508978 0,04784881 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02508978 0,04781149 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02508978 0,04777423 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02508978 0,04773702 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02508978 0,04769987 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02508978 0,04766278 ! UV protection GO:0009650 20 11 0,000 0,02508978 0,04762574 ! adult heart development GO:0007512 16 11 0,000 0,02508978 0,04758877 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02508978 0,04755185 ! macroautophagy GO:0016236 19 11 0,000 0,02508978 0,04751499 ! temperature homeostasis GO:0001659 18 11 0,000 0,02508978 0,04747818 ! behavioral fear response GO:0001662 27 11 0,000 0,02508978 0,04744143 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02508978 0,04740474 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02508978 0,04736811 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02508978 0,04733153 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02508978 0,04729501 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02508978 0,04725854 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02508978 0,04722214 ! regulation of organ growth GO:0046620 14 11 0,000 0,02508978 0,04718578 ! pigment granule localization GO:0051875 20 11 0,000 0,02508978 0,04714949 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02508978 0,04711324 ! vasoconstriction GO:0042310 20 11 0,000 0,02508978 0,04707706 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02508978 0,04704093 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02508978 0,04700486 ! embryonic axis specification GO:0000578 19 11 0,000 0,02508978 0,04696884 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02508978 0,04693287 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02508978 0,04689696 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02508978 0,04686111 ! DNA methylation GO:0006306 19 11 0,000 0,02508978 0,04682531 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02508978 0,04678957 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02508978 0,04675388 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02508978 0,04671824 ! prophase GO:0051324 17 11 0,000 0,02508978 0,04668266 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02508978 0,04664713 ! nucleosome positioning GO:0016584 15 11 0,000 0,02508978 0,04661166 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02508978 0,04657624 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02508978 0,04654087 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02508978 0,04650556 ! apical protein localization GO:0045176 18 11 0,000 0,02508978 0,0464703 ! acid secretion GO:0046717 20 11 0,000 0,02508978 0,0464351 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02508978 0,04639995 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02508978 0,04636485 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02508978 0,0463298 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02508978 0,04629481 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02508978 0,04625987 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02508978 0,04622499 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02508978 0,04619015 ! cholesterol efflux GO:0033344 21 11 0,000 0,02508978 0,04615537 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02508978 0,04612064 ! oocyte development GO:0048599 20 11 0,000 0,02508978 0,04608596 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02508978 0,04605134 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02508978 0,04601677 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02508978 0,04598224 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02508978 0,04594777 ! activation of innate immune response GO:0002218 16 11 0,000 0,02508978 0,04591336 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02508978 0,04587899 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02508978 0,04584468 ! lysogeny GO:0030069 22 11 0,000 0,02508978 0,04581041 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02508978 0,0457762 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02508978 0,04574204 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02508978 0,04570793 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02733959 0,04976947 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02733959 0,04973241 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02733959 0,04969541 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02733959 0,04965846 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02733959 0,04962157 ! protein complex disassembly GO:0043241 28 12 0,000 0,02733959 0,04958473 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02733959 0,04954794 ! hippocampus development GO:0021766 29 12 0,000 0,02733959 0,04951121 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,02733959 0,04947454 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02733959 0,04943792 ! T cell proliferation GO:0042098 32 12 0,000 0,02733959 0,04940135 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02733959 0,04936484 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02733959 0,04932838 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02733959 0,04929198 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02733959 0,04925562 ! drug transport GO:0015893 16 12 0,000 0,02733959 0,04921933 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02733959 0,04918308 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02733959 0,04914689 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02733959 0,04911075 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02733959 0,04907467 ! focal adhesion formation GO:0048041 37 12 0,000 0,02733959 0,04903864 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02733959 0,04900266 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02733959 0,04896674 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02733959 0,04893086 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02733959 0,04889504 ! lipid digestion GO:0044241 21 12 0,000 0,02733959 0,04885927 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02733959 0,04882356 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02733959 0,04878789 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02733959 0,04875228 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02733959 0,04871672 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02733959 0,04868121 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02733959 0,04864576 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02733959 0,04861035 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02733959 0,048575 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02733959 0,0485397 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02733959 0,04850445 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02733959 0,04846925 ! cranial nerve development GO:0021545 23 12 0,000 0,02733959 0,0484341 ! fucose catabolic process GO:0019317 25 12 0,000 0,02733959 0,048399 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02733959 0,04836396 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02733959 0,04832896 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02733959 0,04829402 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02733959 0,04825912 ! zymogen activation GO:0031638 18 12 0,000 0,02733959 0,04822428 ! T cell homeostasis GO:0043029 28 12 0,000 0,02733959 0,04818949 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02733959 0,04815474 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02733959 0,04812005 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02733959 0,0480854 ! oocyte differentiation GO:0009994 21 12 0,000 0,02733959 0,04805081 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02733959 0,04801627 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02733959 0,04798177 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02733959 0,04794733 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02733959 0,04791293 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02733959 0,04787859 ! defense response to fungus GO:0050832 15 12 0,000 0,02733959 0,04784429 ! embryonic placenta development GO:0001892 21 12 0,000 0,02733959 0,04781004 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02733959 0,04777584 ! response to cold GO:0009409 17 12 0,000 0,02733959 0,04774169 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02733959 0,04770759 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02733959 0,04767354 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02958428 0,05155092 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02958428 0,05151418 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02958428 0,05147749 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02958428 0,05144085 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02958428 0,05140426 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02958428 0,05136773 ! peroxisomal transport GO:0043574 28 13 0,000 0,02958428 0,05133124 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02958428 0,05129481 ! cartilage condensation GO:0001502 22 13 0,000 0,02958428 0,05125843 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02958428 0,05122211 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02958428 0,05118583 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02958428 0,05114961 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02958428 0,05111343 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02958428 0,05107731 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02958428 0,05104124 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02958428 0,05100522 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02958428 0,05096925 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02958428 0,05093333 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02958428 0,05089746 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02958428 0,05086164 ! methionine metabolic process GO:0006555 31 13 0,000 0,02958428 0,05082587 ! plasma membrane organization GO:0007009 27 13 0,000 0,02958428 0,05079016 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02958428 0,05075449 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02958428 0,05071887 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02958428 0,0506833 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02958428 0,05064779 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,02958428 0,05061232 ! exocrine system development GO:0035272 34 13 0,000 0,02958428 0,0505769 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02958428 0,05054153 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02958428 0,05050621 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02958428 0,05047094 ! L-glutamate transport GO:0015813 30 13 0,000 0,02958428 0,05043572 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02958428 0,05040055 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02958428 0,05036543 ! protein homotetramerization GO:0051289 24 13 0,000 0,02958428 0,05033036 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02958428 0,05029533 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02958428 0,05026036 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02958428 0,05022543 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02958428 0,05019055 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02958428 0,05015572 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02958428 0,05012094 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02958428 0,0500862 ! histone methylation GO:0016571 29 13 0,000 0,02958428 0,05005152 ! chromatin silencing GO:0006342 29 13 0,000 0,02958428 0,05001688 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02958428 0,04998229 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02958428 0,04994775 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02958428 0,04991325 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02958428 0,04987881 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02958428 0,04984441 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02958428 0,04981006 ! spleen development GO:0048536 24 13 0,000 0,02958428 0,04977575 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02958428 0,0497415 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02958428 0,04970729 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02958428 0,04967312 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02958428 0,04963901 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02958428 0,04960494 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02958428 0,04957091 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02958428 0,04953694 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02958428 0,04950301 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02958428 0,04946913 ! insulin secretion GO:0030073 24 13 0,000 0,02958428 0,04943529 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02958428 0,0494015 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02958428 0,04936775 ! acrosome reaction GO:0007340 19 13 0,000 0,02958428 0,04933406 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02958428 0,0493004 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02958428 0,0492668 ! rRNA transcription GO:0009303 28 14 0,000 0,03182385 0,05296026 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03182385 0,0529242 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03182385 0,0528882 ! water transport GO:0006833 21 14 0,000 0,03182385 0,05285225 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,03182385 0,05281634 ! non-recombinational repair GO:0000726 29 14 0,000 0,03182385 0,05278049 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,03182385 0,05274468 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03182385 0,05270892 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,03182385 0,05267321 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03182385 0,05263755 ! palate development GO:0060021 32 14 0,000 0,03182385 0,05260193 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03182385 0,05256637 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03182385 0,05253085 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03182385 0,05249538 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03182385 0,05245996 ! arginine metabolic process GO:0006525 21 14 0,000 0,03182385 0,05242458 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03182385 0,05238926 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03182385 0,05235398 ! regulation of heart rate GO:0002027 25 14 0,000 0,03182385 0,05231875 ! fear response GO:0042596 34 14 0,000 0,03182385 0,05228356 ! organic alcohol transport GO:0015850 29 14 0,000 0,03182385 0,05224843 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03182385 0,05221334 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03182385 0,05217829 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03182385 0,0521433 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03182385 0,05210835 ! bone mineralization GO:0030282 18 14 0,000 0,03182385 0,05207345 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03182385 0,05203859 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03182385 0,05200378 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03182385 0,05196902 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03182385 0,05193431 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03182385 0,05189964 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03182385 0,05186501 ! ribosome assembly GO:0042255 18 14 0,000 0,03182385 0,05183044 ! cerebellum development GO:0021549 23 14 0,000 0,03182385 0,05179591 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03182385 0,05176142 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03182385 0,05172698 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03182385 0,05169259 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03182385 0,05165824 ! NADP metabolic process GO:0006739 24 14 0,000 0,03182385 0,05162394 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03182385 0,05158969 ! oxygen transport GO:0015671 22 14 0,000 0,03182385 0,05155548 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03182385 0,05152131 ! male genitalia development GO:0030539 26 14 0,000 0,03182385 0,05148719 ! regulation of RNA stability GO:0043487 33 14 0,000 0,03182385 0,05145312 ! regulation of axon extension GO:0030516 43 14 0,000 0,03182385 0,05141909 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03182385 0,0513851 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03405831 0,0549567 ! lactation GO:0007595 30 15 0,000 0,03405831 0,05492043 ! reproductive cellular process GO:0048610 22 15 0,000 0,03405831 0,0548842 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03405831 0,05484802 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,03405831 0,05481189 ! superoxide anion generation GO:0042554 22 15 0,000 0,03405831 0,05477581 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,03405831 0,05473977 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,03405831 0,05470378 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,03405831 0,05466784 ! copper ion transport GO:0006825 22 15 0,000 0,03405831 0,05463194 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,03405831 0,05459609 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,03405831 0,05456029 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,03405831 0,05452454 ! sulfate transport GO:0008272 27 15 0,000 0,03405831 0,05448883 ! response to cAMP GO:0051591 25 15 0,000 0,03405831 0,05445317 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,03405831 0,05441756 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,03405831 0,05438199 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,03405831 0,05434647 ! response to hexose stimulus GO:0009746 25 15 0,000 0,03405831 0,054311 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,03405831 0,05427557 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,03405831 0,05424019 ! vesicle coating GO:0006901 38 15 0,000 0,03405831 0,05420485 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,03405831 0,05416956 ! regulation of exocytosis GO:0017157 26 15 0,000 0,03405831 0,05413432 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,03405831 0,05409912 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,03405831 0,05406397 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,03405831 0,05402886 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,03405831 0,0539938 ! histone deacetylation GO:0016575 24 15 0,000 0,03405831 0,05395879 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03405831 0,05392382 ! water homeostasis GO:0030104 28 15 0,000 0,03405831 0,05388889 ! cofactor transport GO:0051181 30 15 0,000 0,03405831 0,05385401 ! muscle maintenance GO:0046716 26 15 0,000 0,03405831 0,05381918 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,03405831 0,05378439 ! intestinal absorption GO:0050892 31 15 0,000 0,03405831 0,05374964 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03405831 0,05371494 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,03405831 0,05368029 ! heme biosynthetic process GO:0006783 33 15 0,000 0,03405831 0,05364568 ! cell killing GO:0001906 32 15 0,000 0,03405831 0,05361111 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,03405831 0,05357659 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,03405831 0,05354212 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,03405831 0,05350768 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,03405831 0,0534733 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,03405831 0,05343895 ! actin filament polymerization GO:0030041 27 15 0,000 0,03405831 0,05340465 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,03405831 0,0533704 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03628768 0,05682743 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03628768 0,05679103 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03628768 0,05675467 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03628768 0,05671836 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03628768 0,05668209 ! bone remodeling GO:0046849 28 16 0,000 0,03628768 0,05664588 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03628768 0,0566097 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03628768 0,05657358 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03628768 0,0565375 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03628768 0,05650146 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03628768 0,05646547 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03628768 0,05642953 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03628768 0,05639364 ! startle response GO:0001964 28 16 0,000 0,03628768 0,05635778 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03628768 0,05632198 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03628768 0,05628622 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03628768 0,0562505 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03628768 0,05621483 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03628768 0,05617921 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03628768 0,05614363 ! pituitary gland development GO:0021983 30 16 0,000 0,03628768 0,0561081 ! response to osmotic stress GO:0006970 27 16 0,000 0,03628768 0,05607261 ! lysosomal transport GO:0007041 31 16 0,000 0,03628768 0,05603716 ! fructose metabolic process GO:0006000 25 16 0,000 0,03628768 0,05600177 ! L-amino acid transport GO:0015807 33 16 0,000 0,03628768 0,05596641 ! stem cell development GO:0048864 46 16 0,000 0,03628768 0,0559311 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03628768 0,05589584 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03628768 0,05586061 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03628768 0,05582544 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03628768 0,05579031 ! axon cargo transport GO:0008088 46 16 0,000 0,03628768 0,05575522 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03628768 0,05572017 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03628768 0,05568517 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,03628768 0,05565022 ! DNA replication initiation GO:0006270 28 16 0,000 0,03628768 0,0556153 ! neuron recognition GO:0008038 40 16 0,000 0,03628768 0,05558044 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03628768 0,05554561 ! tissue regeneration GO:0042246 27 16 0,000 0,03628768 0,05551083 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03628768 0,05547609 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03628768 0,0554414 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03628768 0,05540675 ! biomineral formation GO:0031214 22 16 0,000 0,03628768 0,05537214 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03628768 0,05533757 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03628768 0,05530305 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03628768 0,05526858 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03628768 0,05523414 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03628768 0,05519975 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03628768 0,0551654 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03628768 0,05513109 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03628768 0,05509683 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,03628768 0,05506261 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03851196 0,05840144 ! metencephalon development GO:0022037 32 17 0,000 0,03851196 0,05836521 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03851196 0,05832903 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03851196 0,05829289 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03851196 0,05825679 ! signal complex assembly GO:0007172 47 17 0,000 0,03851196 0,05822074 ! endothelial cell migration GO:0043542 31 17 0,000 0,03851196 0,05818474 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03851196 0,05814878 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03851196 0,05811286 ! glial cell development GO:0021782 28 17 0,000 0,03851196 0,05807699 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03851196 0,05804116 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03851196 0,05800538 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03851196 0,05796964 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03851196 0,05793394 ! myoblast differentiation GO:0045445 50 17 0,000 0,03851196 0,05789829 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03851196 0,05786268 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03851196 0,05782712 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03851196 0,0577916 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03851196 0,05775612 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03851196 0,05772069 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03851196 0,0576853 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03851196 0,05764995 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03851196 0,05761465 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03851196 0,05757939 ! membrane budding GO:0006900 42 17 0,000 0,03851196 0,05754417 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03851196 0,057509 ! regulation of protein binding GO:0043393 33 17 0,000 0,03851196 0,05747387 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03851196 0,05743878 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03851196 0,05740374 ! genitalia development GO:0048806 32 17 0,000 0,03851196 0,05736873 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03851196 0,05733377 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03851196 0,05729886 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03851196 0,05726398 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03851196 0,05722915 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03851196 0,05719436 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03851196 0,05715961 ! steroid catabolic process GO:0006706 34 17 0,000 0,03851196 0,05712491 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03851196 0,05709025 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03851196 0,05705562 ! gas transport GO:0015669 26 17 0,000 0,03851196 0,05702104 ! organic cation transport GO:0015695 32 17 0,000 0,03851196 0,05698651 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03851196 0,05695201 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03851196 0,05691756 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03851196 0,05688315 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,04073118 0,06012463 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04073118 0,06008832 ! limbic system development GO:0021761 40 18 0,000 0,04073118 0,06005206 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04073118 0,06001584 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04073118 0,05997966 ! adult walking behavior GO:0007628 36 18 0,000 0,04073118 0,05994353 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04073118 0,05990744 ! heart looping GO:0001947 34 18 0,000 0,04073118 0,0598714 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04073118 0,0598354 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04073118 0,05979944 ! centrosome cycle GO:0007098 26 18 0,000 0,04073118 0,05976352 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04073118 0,05972765 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,04073118 0,05969182 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,04073118 0,05965603 ! glycine metabolic process GO:0006544 30 18 0,000 0,04073118 0,05962029 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04073118 0,05958459 ! response to retinoic acid GO:0032526 31 18 0,000 0,04073118 0,05954893 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,04073118 0,05951332 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,04073118 0,05947774 ! DNA integration GO:0015074 32 18 0,000 0,04073118 0,05944221 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,04073118 0,05940672 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,04073118 0,05937128 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,04073118 0,05933588 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04073118 0,05930051 ! neural crest cell migration GO:0001755 41 18 0,000 0,04073118 0,0592652 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04073118 0,05922992 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04073118 0,05919468 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,04073118 0,05915949 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04073118 0,05912434 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,04073118 0,05908923 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,04073118 0,05905416 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04073118 0,05901914 ! detection of bacterium GO:0016045 22 18 0,000 0,04073118 0,05898415 ! nerve development GO:0021675 34 18 0,000 0,04073118 0,05894921 ! defense response to virus GO:0051607 43 18 0,000 0,04073118 0,05891431 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04073118 0,05887945 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,04073118 0,05884463 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,04294533 0,06200676 ! positive regulation of translation GO:0045727 31 19 0,000 0,04294533 0,06197014 ! negative regulation of defense response GO:0031348 27 19 0,000 0,04294533 0,06193356 ! neuron maturation GO:0042551 46 19 0,000 0,04294533 0,06189702 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,04294533 0,06186052 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,04294533 0,06182407 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,04294533 0,06178766 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,04294533 0,06175129 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,04294533 0,06171497 ! inositol metabolic process GO:0006020 33 19 0,000 0,04294533 0,06167868 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04294533 0,06164245 ! memory GO:0007613 34 19 0,000 0,04294533 0,06160625 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,04294533 0,0615701 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,04294533 0,06153398 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,04294533 0,06149791 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,04294533 0,06146189 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,04294533 0,0614259 ! cerebral cortex development GO:0021987 40 19 0,000 0,04294533 0,06138996 ! pigmentation during development GO:0048066 42 19 0,000 0,04294533 0,06135406 ! response to vitamin A GO:0033189 32 19 0,000 0,04294533 0,0613182 ! heme metabolic process GO:0042168 40 19 0,000 0,04294533 0,06128238 ! neuromuscular junction development GO:0007528 43 19 0,000 0,04294533 0,06124661 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,04294533 0,06121088 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,04294533 0,06117519 ! peptide cross-linking GO:0018149 39 19 0,000 0,04294533 0,06113954 ! protein export from nucleus GO:0006611 40 19 0,000 0,04294533 0,06110393 ! heart process GO:0003015 32 19 0,000 0,04294533 0,06106836 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,04294533 0,06103283 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,04294533 0,06099735 ! visual learning GO:0008542 38 19 0,000 0,04294533 0,06096191 ! cellular pigmentation GO:0033059 37 19 0,000 0,04294533 0,06092651 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,04294533 0,06089114 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,04294533 0,06085583 ! vitamin transport GO:0051180 31 19 0,000 0,04294533 0,06082055 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,04294533 0,06078531 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,04294533 0,06075011 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,04294533 0,06071496 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,04294533 0,06067984 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,04294533 0,06064476 ! cilium assembly GO:0042384 38 19 0,000 0,04294533 0,06060973 ! peptide hormone secretion GO:0030072 32 19 0,000 0,04294533 0,06057474 ! protein secretion GO:0009306 45 20 0,000 0,04515444 0,06365395 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04515444 0,06361724 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04515444 0,06358057 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04515444 0,06354394 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04515444 0,06350736 ! skin development GO:0043588 42 20 0,000 0,04515444 0,06347082 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04515444 0,06343432 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04515444 0,06339787 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,04515444 0,06336145 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04515444 0,06332508 ! response to vitamin GO:0033273 36 20 0,000 0,04515444 0,06328875 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04515444 0,06325246 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04515444 0,06321621 ! response to alkaloid GO:0043279 38 20 0,000 0,04515444 0,06318 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04515444 0,06314384 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,04515444 0,06310772 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04515444 0,06307163 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04515444 0,06303559 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04515444 0,06299959 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,04515444 0,06296363 ! actin filament bundle formation GO:0051017 47 20 0,000 0,04515444 0,06292772 ! body fluid secretion GO:0007589 33 20 0,000 0,04515444 0,06289184 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04515444 0,062856 ! peptide secretion GO:0002790 38 20 0,000 0,04515444 0,06282021 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04515444 0,06278446 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04515444 0,06274874 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04515444 0,06271307 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04515444 0,06267744 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04515444 0,06264184 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,04515444 0,06260629 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04515444 0,06257078 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04515444 0,06253531 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04515444 0,06249988 ! regulation of glucose import GO:0046324 30 20 0,000 0,04515444 0,06246449 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04515444 0,06242914 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04515444 0,06239383 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04515444 0,06235856 ! negative regulation of translation GO:0017148 32 20 0,000 0,04515444 0,06232333 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04515444 0,06228814 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04735851 0,06529166 ! hormone secretion GO:0046879 39 21 0,000 0,04735851 0,06525484 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04735851 0,06521805 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04735851 0,06518131 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04735851 0,06514461 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04735851 0,06510795 ! ovarian follicle development GO:0001541 39 21 0,000 0,04735851 0,06507133 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04735851 0,06503475 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04735851 0,06499822 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04735851 0,06496172 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04735851 0,06492527 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04735851 0,06488885 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04735851 0,06485248 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04735851 0,06481615 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,04735851 0,06477986 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04735851 0,06474361 ! diencephalon development GO:0021536 36 21 0,000 0,04735851 0,0647074 ! collagen fibril organization GO:0030199 62 21 0,000 0,04735851 0,06467123 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04735851 0,0646351 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04735851 0,06459901 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04735851 0,06456296 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04735851 0,06452695 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,04735851 0,06449099 ! collagen catabolic process GO:0030574 29 21 0,000 0,04735851 0,06445506 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04735851 0,06441917 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04735851 0,06438332 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04735851 0,06434751 ! actin filament-based movement GO:0030048 47 21 0,000 0,04735851 0,06431174 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04955755 0,06726061 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04955755 0,06722326 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04955755 0,06718595 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04955755 0,06714869 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04955755 0,06711147 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04955755 0,06707429 ! microtubule-based transport GO:0010970 59 22 0,000 0,04955755 0,06703715 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04955755 0,06700005 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04955755 0,06696299 ! vacuolar transport GO:0007034 41 22 0,000 0,04955755 0,06692598 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04955755 0,066889 ! fucose metabolic process GO:0006004 44 22 0,000 0,04955755 0,06685207 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04955755 0,06681517 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04955755 0,06677832 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04955755 0,0667415 ! ureteric bud development GO:0001657 50 22 0,000 0,04955755 0,06670473 ! stem cell differentiation GO:0048863 57 22 0,000 0,04955755 0,066668 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04955755 0,06663131 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04955755 0,06659466 ! cytolysis GO:0019835 27 22 0,000 0,04955755 0,06655805 ! renal system process GO:0003014 42 22 0,000 0,04955755 0,06652148 ! vasodilation GO:0042311 40 22 0,000 0,04955755 0,06648495 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04955755 0,06644846 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04955755 0,06641201 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04955755 0,0663756 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04955755 0,06633923 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,04955755 0,0663029 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04955755 0,06626661 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04955755 0,06623036 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04955755 0,06619414 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04955755 0,06615797 ! sarcomere organization GO:0045214 32 22 0,000 0,04955755 0,06612184 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04955755 0,06608575 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04955755 0,06604969 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04955755 0,06601368 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04955755 0,06597771 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04955755 0,06594177 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04955755 0,06590587 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04955755 0,06587002 ! protein stabilization GO:0050821 41 22 0,000 0,04955755 0,0658342 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,05175158 0,06871147 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,05175158 0,06867415 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,05175158 0,06863686 ! gluconeogenesis GO:0006094 38 23 0,000 0,05175158 0,06859962 ! glycerol metabolic process GO:0006071 40 23 0,000 0,05175158 0,06856242 ! viral genome replication GO:0019079 44 23 0,000 0,05175158 0,06852526 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,05175158 0,06848814 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,05175158 0,06845106 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,05175158 0,06841402 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,05175158 0,06837702 ! regeneration GO:0031099 42 23 0,000 0,05175158 0,06834005 ! axis specification GO:0009798 43 23 0,000 0,05175158 0,06830313 ! visual behavior GO:0007632 46 23 0,000 0,05175158 0,06826625 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,05175158 0,06822941 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 0,000 0,05175158 0,06819261 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,05175158 0,06815585 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,05175158 0,06811913 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,05175158 0,06808245 ! peroxisome organization GO:0007031 43 23 0,000 0,05175158 0,0680458 ! lysosome organization GO:0007040 47 23 0,000 0,05175158 0,0680092 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,05175158 0,06797264 ! vesicle targeting GO:0006903 49 23 0,000 0,05175158 0,06793611 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,05175158 0,06789962 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,05175158 0,06786318 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,05175158 0,06782677 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,05175158 0,0677904 ! DNA modification GO:0006304 36 23 0,000 0,05175158 0,06775407 ! fatty acid transport GO:0015908 47 23 0,000 0,05175158 0,06771778 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,05175158 0,06768153 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,05175158 0,06764532 ! hormone transport GO:0009914 41 23 0,000 0,05175158 0,06760915 ! cell-cell recognition GO:0009988 28 23 0,000 0,05175158 0,06757301 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,05175158 0,06753691 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,05175158 0,06750086 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,05175158 0,06746484 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0539406 0,07028101 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0539406 0,07024355 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,0539406 0,07020612 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,0539406 0,07016874 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0539406 0,07013139 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0539406 0,07009409 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0539406 0,07005683 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0539406 0,0700196 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,0539406 0,06998242 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0539406 0,06994527 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0539406 0,06990816 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0539406 0,0698711 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,0539406 0,06983407 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0539406 0,06979708 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0539406 0,06976013 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0539406 0,06972322 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0539406 0,06968635 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0539406 0,06964952 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0539406 0,06961273 ! pallium development GO:0021543 56 24 0,000 0,0539406 0,06957597 ! oogenesis GO:0048477 44 24 0,000 0,0539406 0,06953926 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0539406 0,06950258 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0539406 0,06946594 ! platelet activation GO:0030168 41 24 0,000 0,0539406 0,06942934 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0539406 0,06939278 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0539406 0,06935626 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0539406 0,06931977 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0539406 0,06928333 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0539406 0,06924692 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0539406 0,06921055 ! regulation of amine transport GO:0051952 41 24 0,000 0,0539406 0,06917422 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,05612464 0,0719373 ! leukocyte adhesion GO:0007159 55 25 0,000 0,05612464 0,07189957 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,05612464 0,07186189 ! phototransduction GO:0007602 37 25 0,000 0,05612464 0,07182425 ! keratinization GO:0031424 37 25 0,000 0,05612464 0,07178664 ! vacuole organization GO:0007033 49 25 0,000 0,05612464 0,07174908 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,05612464 0,07171155 ! receptor metabolic process GO:0043112 53 25 0,000 0,05612464 0,07167406 ! chromosome condensation GO:0030261 48 25 0,000 0,05612464 0,07163662 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,05612464 0,07159921 ! regulation of behavior GO:0050795 48 25 0,000 0,05612464 0,07156184 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,05612464 0,07152451 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,05612464 0,07148722 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,05612464 0,07144997 ! immunoglobulin production GO:0002377 62 25 0,000 0,05612464 0,07141275 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,05612464 0,07137558 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,05612464 0,07133844 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,05612464 0,07130134 ! liver development GO:0001889 55 25 0,000 0,05612464 0,07126429 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05830369 0,07399268 ! myelination GO:0042552 50 26 0,000 0,05830369 0,07395426 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05830369 0,07391589 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05830369 0,07387755 ! molting cycle process GO:0022404 52 26 0,000 0,05830369 0,07383925 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05830369 0,07380099 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05830369 0,07376277 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,05830369 0,07372459 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05830369 0,07368645 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05830369 0,07364835 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05830369 0,07361029 ! digestive system process GO:0022600 49 26 0,000 0,05830369 0,07357227 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05830369 0,07353429 ! neural crest cell development GO:0014032 59 26 0,000 0,05830369 0,07349634 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05830369 0,07345844 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05830369 0,07342057 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05830369 0,07338275 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05830369 0,07334496 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05830369 0,07330721 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05830369 0,0732695 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,05830369 0,07323183 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05830369 0,0731942 ! blastocyst development GO:0001824 50 26 0,000 0,05830369 0,07315661 ! telomere organization GO:0032200 46 26 0,000 0,05830369 0,07311905 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05830369 0,07308153 ! neural tube closure GO:0001843 58 26 0,000 0,05830369 0,07304406 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05830369 0,07300662 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05830369 0,07296922 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05830369 0,07293185 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,06047777 0,07561269 ! embryonic pattern specification GO:0009880 49 27 0,000 0,06047777 0,07557401 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,06047777 0,07553538 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,06047777 0,07549678 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,06047777 0,07545822 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,06047777 0,0754197 ! iron ion transport GO:0006826 65 27 0,000 0,06047777 0,07538122 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,06047777 0,07534278 ! superoxide metabolic process GO:0006801 41 27 0,000 0,06047777 0,07530438 ! tube lumen formation GO:0035148 59 27 0,000 0,06047777 0,07526602 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,06047777 0,0752277 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,06047777 0,07518941 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,06047777 0,07515117 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,06047777 0,07511296 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,06047777 0,0750748 ! leukocyte proliferation GO:0070661 59 27 0,000 0,06047777 0,07503667 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,06047777 0,07499858 ! neuron fate commitment GO:0048663 52 28 0,000 0,0626469 0,0776491 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,0626469 0,07760972 ! circadian rhythm GO:0007623 56 28 0,000 0,0626469 0,07757039 ! dendrite development GO:0016358 67 28 0,000 0,0626469 0,07753109 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,0626469 0,07749183 ! fat cell differentiation GO:0045444 57 28 0,000 0,0626469 0,07745262 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,0626469 0,07741344 ! sperm motility GO:0030317 37 28 0,000 0,0626469 0,0773743 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,0626469 0,0773352 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,0626469 0,07729615 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,0626469 0,07725713 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,0626469 0,07721815 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,0626469 0,07717921 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,0626469 0,07714031 ! glutathione metabolic process GO:0006749 42 28 0,000 0,0626469 0,07710145 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,0626469 0,07706262 ! lipid oxidation GO:0034440 48 28 0,000 0,0626469 0,07702384 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,0626469 0,0769851 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,0626469 0,07694639 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,06481108 0,07956455 ! translational initiation GO:0006413 66 29 0,000 0,06481108 0,07952459 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,06481108 0,07948467 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,06481108 0,07944479 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,06481108 0,07940494 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,06481108 0,07936514 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,06481108 0,07932538 ! primary neural tube formation GO:0014020 61 29 0,000 0,06481108 0,07928566 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,06481108 0,07924597 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,06481108 0,07920633 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,06481108 0,07916673 ! synaptogenesis GO:0007416 46 29 0,000 0,06481108 0,07912716 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,06481108 0,07908764 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,06481108 0,07904816 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,06481108 0,07900871 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,06481108 0,07896931 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,06697032 0,08155956 ! phenol metabolic process GO:0018958 56 30 0,000 0,06697032 0,08151893 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,06697032 0,08147833 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,06697032 0,08143777 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,06697032 0,08139726 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,06697032 0,08135678 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,06697032 0,08131634 ! acute-phase response GO:0006953 50 30 0,000 0,06697032 0,08127595 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,06697032 0,08123559 ! myofibril assembly GO:0030239 50 30 0,000 0,06697032 0,08119528 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,06697032 0,081155 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,06697032 0,08111477 ! cell fate determination GO:0001709 64 30 0,000 0,06697032 0,08107457 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,06697032 0,08103442 ! phospholipid transport GO:0015914 65 30 0,000 0,06697032 0,0809943 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,06697032 0,08095422 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,06697032 0,08091419 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,06697032 0,08087419 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,06697032 0,08083423 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,06697032 0,08079431 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06912464 0,08335216 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06912464 0,08331104 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06912464 0,08326996 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06912464 0,08322892 ! cell junction assembly GO:0034329 85 31 0,000 0,06912464 0,08318792 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06912464 0,08314696 ! ovulation cycle process GO:0022602 55 31 0,000 0,06912464 0,08310605 ! peptide transport GO:0015833 60 31 0,000 0,06912464 0,08306517 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06912464 0,08302433 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,06912464 0,08298353 ! detection of light stimulus GO:0009583 44 31 0,000 0,06912464 0,08294277 ! natural killer cell activation GO:0030101 50 31 0,000 0,06912464 0,08290205 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06912464 0,08286138 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06912464 0,08282074 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,06912464 0,08278014 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06912464 0,08273958 ! eye morphogenesis GO:0048592 65 31 0,000 0,06912464 0,08269906 ! response to heat GO:0009408 54 31 0,000 0,06912464 0,08265858 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,06912464 0,08261814 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,07127404 0,08514547 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,07127404 0,08510385 ! collagen metabolic process GO:0032963 49 32 0,000 0,07127404 0,08506228 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,07127404 0,08502074 ! spindle organization GO:0007051 50 32 0,000 0,07127404 0,08497925 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,07127404 0,08493779 ! metanephros development GO:0001656 81 32 0,000 0,07127404 0,08489638 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,07127404 0,08485501 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,07127404 0,08481368 ! muscle cell development GO:0055001 52 32 0,000 0,07127404 0,08477238 ! mesoderm formation GO:0001707 73 32 0,000 0,07127404 0,08473113 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,07127404 0,08468992 ! ovulation cycle GO:0042698 57 32 0,000 0,07127404 0,08464875 ! peripheral nervous system development GO:0007422 68 32 0,000 0,07127404 0,08460762 ! BMP signaling pathway GO:0030509 71 32 0,000 0,07127404 0,08456653 ! hindbrain development GO:0030902 65 32 0,000 0,07127404 0,08452547 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,07127404 0,08448446 ! gene silencing GO:0016458 71 32 0,000 0,07127404 0,08444349 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,07341854 0,08694207 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,07341854 0,08689995 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,07341854 0,08685787 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,07341854 0,08681582 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,07341854 0,08677382 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,07341854 0,08673186 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,07341854 0,08668994 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,07341854 0,08664806 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,07341854 0,08660623 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,07555815 0,08908714 ! glial cell differentiation GO:0010001 67 34 0,000 0,07555815 0,08904417 ! post-embryonic development GO:0009791 76 34 0,000 0,07555815 0,08900123 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,07555815 0,08895834 ! spliceosome assembly GO:0000245 75 34 0,000 0,07555815 0,08891549 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,07555815 0,08887268 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,07555815 0,08882991 ! formation of primary germ layer GO:0001704 76 34 0,000 0,07555815 0,08878719 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,07555815 0,0887445 ! adult locomotory behavior GO:0008344 62 34 0,000 0,07555815 0,08870186 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,07769288 0,09116412 ! negative regulation of secretion GO:0051048 68 35 0,000 0,07769288 0,09112036 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,07769288 0,09107663 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,07769288 0,09103295 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,07769288 0,09098931 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,07769288 0,09094571 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,07769288 0,09090216 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,07769288 0,09085864 ! ceramide metabolic process GO:0006672 72 35 0,000 0,07769288 0,09081517 ! telencephalon development GO:0021537 81 35 0,000 0,07769288 0,09077174 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,07769288 0,09072835 ! placenta development GO:0001890 53 35 0,000 0,07769288 0,090685 ! vesicle localization GO:0051648 70 35 0,000 0,07769288 0,09064169 ! regulation of muscle development GO:0048634 82 36 0,000 0,07982274 0,09308208 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,07982274 0,09303767 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,07982274 0,0929933 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,07982274 0,09294898 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,07982274 0,09290469 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,07982274 0,09286045 ! positive regulation of cell development GO:0010720 85 36 0,000 0,07982274 0,09281625 ! protein targeting to membrane GO:0006612 75 36 0,000 0,07982274 0,0927721 ! regulation of proteolysis GO:0030162 77 36 0,000 0,07982274 0,09272798 ! aerobic respiration GO:0009060 56 36 0,000 0,07982274 0,09268391 ! cytokine production GO:0001816 68 36 0,000 0,07982274 0,09263988 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,07982274 0,09259589 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,07982274 0,09255195 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,08194774 0,09497074 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,08194774 0,09492571 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,08194774 0,09488072 ! sister chromatid segregation GO:0000819 65 37 0,000 0,08194774 0,09483578 ! odontogenesis GO:0042476 74 37 0,000 0,08194774 0,09479088 ! actomyosin structure organization GO:0031032 68 37 0,000 0,08194774 0,09474601 ! cell junction organization GO:0034330 96 37 0,000 0,08194774 0,0947012 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,08194774 0,09465642 ! female gonad development GO:0008585 71 37 0,000 0,08194774 0,09461169 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,08194774 0,09456699 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,08194774 0,09452235 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,08194774 0,09447774 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,08406789 0,09687635 ! meiosis I GO:0007127 74 38 0,000 0,08406789 0,09683068 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,08406789 0,09678504 ! organic anion transport GO:0015711 82 38 0,000 0,08406789 0,09673946 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,08406789 0,09669391 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,08406789 0,09664841 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,08406789 0,09660295 ! regulation of protein stability GO:0031647 77 38 0,000 0,08406789 0,09655753 ! spermatid development GO:0007286 69 38 0,000 0,08406789 0,09651215 ! glycogen metabolic process GO:0005977 63 38 0,000 0,08406789 0,09646682 ! pigment metabolic process GO:0042440 87 38 0,000 0,08406789 0,09642153 ! neural tube formation GO:0001841 79 38 0,000 0,08406789 0,09637628 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,08618321 0,09875496 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,08618321 0,09870866 ! negative regulation of binding GO:0051100 71 39 0,000 0,08618321 0,09866241 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,08618321 0,0986162 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,08618321 0,09857003 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,08618321 0,0985239 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,08618321 0,09847782 ! glucan metabolic process GO:0044042 64 39 0,000 0,08618321 0,09843178 GO:0006073|cellular glucan metabolic process, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,0882937 0,1007951 ! learning GO:0007612 82 40 0,000 0,0882937 0,10074802 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,0882937 0,10070099 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,0882937 0,10065399 ! mismatch repair GO:0006298 58 40 0,000 0,0882937 0,10060705 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,0882937 0,10056014 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,0882937 0,10051329 ! RNA export from nucleus GO:0006405 61 41 0,000 0,09039938 0,10286245 ! mRNA catabolic process GO:0006402 79 41 0,000 0,09039938 0,10281456 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,09039938 0,10276672 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,09039938 0,10271892 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,09039938 0,10267117 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,09039938 0,10262346 ! gliogenesis GO:0042063 91 41 0,000 0,09039938 0,10257579 ! feeding behavior GO:0007631 69 41 0,000 0,09039938 0,10252817 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,09039938 0,10248059 ! mesenchymal cell development GO:0014031 94 41 0,000 0,09039938 0,10243306 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,09039938 0,10238557 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,09039938 0,10233813 ! spermatid differentiation GO:0048515 73 41 0,000 0,09039938 0,10229073 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,09039938 0,10224337 ! RNA modification GO:0009451 64 41 0,000 0,09039938 0,10219606 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,09250025 0,10452271 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,09250025 0,10447439 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,09250025 0,10442611 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,09250025 0,10437788 ! regulation of protein secretion GO:0050708 77 42 0,000 0,09250025 0,10432969 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,09250025 0,10428154 ! cytokinesis GO:0000910 84 42 0,000 0,09250025 0,10423344 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,09459633 0,10654625 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,09459633 0,10649716 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,09459633 0,1064481 ! regulation of tube size GO:0035150 76 43 0,000 0,09459633 0,10639909 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,09459633 0,10635013 ! glucose transport GO:0015758 66 43 0,000 0,09459633 0,10630121 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,09459633 0,10625233 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,09459633 0,1062035 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,09459633 0,10615472 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,09459633 0,10610598 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,09459633 0,10605729 ! ion transmembrane transport GO:0034220 79 43 0,000 0,09459633 0,10600864 ! neuron migration GO:0001764 85 43 0,000 0,09459633 0,10596003 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,09459633 0,10591147 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,09668762 0,10820333 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,09668762 0,10815378 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,09668762 0,10810428 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,09668762 0,10805483 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,09668762 0,10800542 ! hexose transport GO:0008645 68 44 0,000 0,09668762 0,10795606 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,09668762 0,10790674 ! striated muscle contraction GO:0006941 85 44 0,000 0,09668762 0,10785747 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,09668762 0,10780824 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,09877415 0,11008451 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,09877415 0,11003431 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,09877415 0,10998416 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,09877415 0,10993405 ! biopolymer methylation GO:0043414 91 45 0,000 0,09877415 0,10988399 ! female gamete generation GO:0007292 71 45 0,000 0,09877415 0,10983397 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,09877415 0,109784 ! polyol metabolic process GO:0019751 77 45 0,000 0,09877415 0,10973408 ! developmental growth GO:0048589 88 45 0,000 0,09877415 0,1096842 ! maintenance of location in cell GO:0051651 101 45 0,000 0,09877415 0,10963437 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,10085591 0,11189418 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,10085591 0,11184339 ! glycolysis GO:0006096 71 46 0,000 0,10085591 0,11179265 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,10085591 0,11174195 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,10085591 0,11169129 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,10085591 0,11164068 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,10085591 0,11159012 ! pigmentation GO:0043473 103 46 0,000 0,10085591 0,11153961 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,10085591 0,11148914 ! neural tube development GO:0021915 91 47 0,000 0,10293292 0,11373366 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,10293292 0,11368225 ! positive regulation of defense response GO:0031349 88 48 0,000 0,1050052 0,11591853 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,1050052 0,11586617 ! cellular component disassembly GO:0022411 89 48 0,000 0,1050052 0,11581386 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,1050052 0,1157616 ! endosome transport GO:0016197 127 48 0,000 0,1050052 0,11570938 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,1050052 0,11565721 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,1050052 0,11560509 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,1050052 0,11555302 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,1050052 0,11550099 ! methylation GO:0032259 97 48 0,000 0,1050052 0,11544901 ! response to calcium ion GO:0051592 94 49 0,000 0,10707274 0,11766924 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,10707274 0,11761633 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,10707274 0,11756347 ! JNK cascade GO:0007254 106 49 0,000 0,10707274 0,11751065 ! regulation of action potential GO:0001508 102 50 0,000 0,10913557 0,11972079 ! regulation of ion transport GO:0043269 86 50 0,000 0,10913557 0,11966705 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,10913557 0,11961337 ! endocrine system development GO:0035270 109 50 0,000 0,10913557 0,11955973 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,10913557 0,11950614 ! regulation of ossification GO:0030278 123 50 0,000 0,10913557 0,1194526 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,10913557 0,1193991 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,10913557 0,11934566 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,10913557 0,11929226 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,10913557 0,11923891 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,11119369 0,12143325 ! peptide metabolic process GO:0006518 80 51 0,000 0,11119369 0,12137899 ! response to temperature stimulus GO:0009266 84 51 0,000 0,11119369 0,12132478 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,11119369 0,12127062 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,11324711 0,12345502 ! Notch signaling pathway GO:0007219 111 52 0,000 0,11324711 0,12339995 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,11324711 0,12334494 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,11324711 0,12328997 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,11324711 0,12323505 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,11324711 0,12318018 ! excretion GO:0007588 87 52 0,000 0,11324711 0,12312536 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,11324711 0,12307059 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,11324711 0,12301587 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,11324711 0,1229612 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,11324711 0,12290657 ! amino acid activation GO:0043038 98 52 0,000 0,11324711 0,12285199 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,11529585 0,12501898 ! chromatin remodeling GO:0006338 122 53 0,000 0,11529585 0,12496351 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,11529585 0,12490809 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,11529585 0,12485273 ! synapse organization GO:0050808 102 53 0,000 0,11529585 0,12479741 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,11733991 0,12695367 ! regulation of translational initiation GO:0006446 87 54 0,000 0,11733991 0,12689747 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,11733991 0,12684132 ! neuromuscular process GO:0050905 107 54 0,000 0,11733991 0,12678522 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,11733991 0,12672917 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,11733991 0,12667317 ! regulation of cell shape GO:0008360 142 54 0,000 0,11733991 0,12661722 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,11733991 0,12656132 ! RNA catabolic process GO:0006401 103 55 0,000 0,1193793 0,12870416 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,1193793 0,12864739 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,1193793 0,12859067 ! cell recognition GO:0008037 98 55 0,000 0,1193793 0,12853399 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,1193793 0,12847737 ! cell maturation GO:0048469 107 55 0,000 0,1193793 0,1284208 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,1193793 0,12836428 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,12141404 0,13049472 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,12141404 0,13043734 ! glucose catabolic process GO:0006007 88 56 0,000 0,12141404 0,13038 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,12141404 0,13032272 ! RNA elongation GO:0006354 90 56 0,000 0,12141404 0,13026548 ! chloride transport GO:0006821 102 57 0,000 0,12344414 0,13238544 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,12344414 0,13232735 ! muscle fiber development GO:0048747 131 57 0,000 0,12344414 0,13226931 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,12344414 0,13221132 ! regulation of actin filament length GO:0030832 118 58 0,000 0,1254696 0,13432175 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,1254696 0,13426291 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,1254696 0,13420413 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,1254696 0,1341454 ! gastrulation GO:0007369 122 58 0,000 0,1254696 0,13408672 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,1254696 0,13402809 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,1254696 0,13396951 ! maintenance of location GO:0051235 124 58 0,000 0,1254696 0,13391098 ! nuclear export GO:0051168 110 59 0,000 0,12749044 0,13600836 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,12950667 0,13809899 ! DNA catabolic process GO:0006308 94 60 0,000 0,12950667 0,13803874 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,12950667 0,13797854 ! adult behavior GO:0030534 104 60 0,000 0,12950667 0,13791839 ! kidney development GO:0001822 133 60 0,000 0,12950667 0,13785829 ! positive regulation of secretion GO:0051047 110 61 0,000 0,13151829 0,13993867 ! regulation of cellular component size GO:0032535 125 61 0,000 0,13151829 0,13987775 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,13151829 0,13981688 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,13151829 0,13975606 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,13151829 0,1396953 ! regulation of heart contraction GO:0008016 123 61 0,000 0,13151829 0,13963459 ! camera-type eye development GO:0043010 126 61 0,000 0,13151829 0,13957393 ! proton transport GO:0015992 117 61 0,000 0,13151829 0,13951332 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,13352532 0,14158088 ! tRNA processing GO:0008033 102 62 0,000 0,13352532 0,14151946 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,13352532 0,14145809 ! regulation of mitosis GO:0007088 112 63 0,000 0,13552777 0,14351727 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,13552777 0,14345509 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,13552777 0,14339296 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,13552777 0,14333088 ! hydrogen transport GO:0006818 121 64 0,000 0,13752565 0,14538086 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,13752565 0,14531798 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,13752565 0,14525515 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,13951897 0,14729682 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,13951897 0,14723319 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,13951897 0,14716962 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,13951897 0,1471061 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,14150773 0,14913865 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,14150773 0,14907434 ! chromosome segregation GO:0007059 127 67 0,000 0,14349196 0,15109951 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,14349196 0,15103441 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,14349196 0,15096936 ! secondary metabolic process GO:0019748 125 67 0,000 0,14349196 0,15090437 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,14547165 0,1529205 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,14547165 0,15285473 ! hexose catabolic process GO:0019320 113 68 0,000 0,14547165 0,15278902 ! extracellular matrix organization GO:0030198 146 68 0,000 0,14547165 0,15272336 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,14547165 0,15265775 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,14547165 0,15259221 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,14547165 0,15252672 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,14744683 0,15453136 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,14744683 0,1544651 ! urogenital system development GO:0001655 149 69 0,000 0,14744683 0,15439889 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,14744683 0,15433274 ! developmental maturation GO:0021700 128 69 0,000 0,14744683 0,15426664 ! single fertilization GO:0007338 83 69 0,000 0,14744683 0,1542006 ! cell redox homeostasis GO:0045454 114 70 0,000 0,1494175 0,15619467 ! germ cell development GO:0007281 133 70 0,000 0,1494175 0,15612786 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,15138366 0,1581147 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,15138366 0,15804713 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,15138366 0,15797962 ! carbohydrate transport GO:0008643 114 72 0,000 0,15334534 0,15995844 ! actin filament organization GO:0007015 167 72 0,000 0,15334534 0,15989017 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,15334534 0,15982195 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,15334534 0,1597538 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,15334534 0,1596857 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,15334534 0,15961766 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,15530253 0,16158607 ! amino acid transport GO:0006865 148 74 0,000 0,15725526 0,16354815 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,15725526 0,16347855 ! transition metal ion transport GO:0000041 143 75 0,000 0,15920353 0,16543353 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,15920353 0,16536319 ! eye development GO:0001654 155 75 0,000 0,15920353 0,16529291 ! axon guidance GO:0007411 162 75 0,000 0,15920353 0,16522269 ! rhythmic process GO:0048511 142 75 0,000 0,15920353 0,16515254 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,16114735 0,16709804 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,16114735 0,16702714 ! learning or memory GO:0007611 161 76 0,000 0,16114735 0,16695631 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,16114735 0,16688553 ! regulation of blood pressure GO:0008217 134 76 0,000 0,16114735 0,16681482 ! amine catabolic process GO:0009310 136 77 0,000 0,16308673 0,1687509 ! neurotransmitter transport GO:0006836 142 77 0,000 0,16308673 0,16867946 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,16308673 0,16860807 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,16308673 0,16853675 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,16308673 0,16846549 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,16502168 0,17039221 ! antigen processing and presentation GO:0019882 117 78 0,000 0,16502168 0,17032022 ! fertilization GO:0009566 99 78 0,000 0,16502168 0,17024829 ! blood coagulation GO:0007596 151 79 0,000 0,16695221 0,17216726 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,16695221 0,17209462 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,16695221 0,17202204 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,16695221 0,17194951 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,16695221 0,17187705 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,16695221 0,17180465 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,16887833 0,17371358 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,16887833 0,17364047 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,16887833 0,17356742 ! meiosis GO:0007126 143 81 0,000 0,17080005 0,17546868 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,17080005 0,17539493 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,17080005 0,17532123 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,17271739 0,17721486 ! meiotic cell cycle GO:0051321 144 82 0,000 0,17271739 0,17714046 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,17463034 0,17902725 ! exocytosis GO:0006887 153 83 0,000 0,17463034 0,17895215 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,17463034 0,17887712 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,17463034 0,17880215 ! inorganic anion transport GO:0015698 156 83 0,000 0,17463034 0,17872724 ! response to metal ion GO:0010038 158 84 0,000 0,17653893 0,18060494 ! response to nutrient GO:0007584 135 84 0,000 0,17653893 0,18052934 ! digestion GO:0007586 130 84 0,000 0,17653893 0,18045381 ! regulation of ligase activity GO:0051340 147 84 0,000 0,17653893 0,18037833 ! hemostasis GO:0007599 165 85 0,000 0,17844315 0,18224775 ! negative regulation of transport GO:0051051 164 85 0,000 0,17844315 0,18217159 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,17844315 0,1820955 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,17844315 0,18201946 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,17844315 0,1819435 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,17844315 0,18186759 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,18034303 0,18372728 ! regulation of lyase activity GO:0051339 169 86 0,000 0,18034303 0,18365069 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,18223856 0,18550367 ! alcohol catabolic process GO:0046164 142 87 0,000 0,18223856 0,18542641 ! nucleosome assembly GO:0006334 126 87 0,000 0,18223856 0,18534921 ! regulation of protein transport GO:0051223 165 87 0,000 0,18223856 0,18527208 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,18412977 0,1871169 ! amine biosynthetic process GO:0009309 146 88 0,000 0,18412977 0,18703909 ! sensory perception of smell GO:0007608 117 88 0,000 0,18412977 0,18696135 ! chromatin assembly GO:0031497 128 88 0,000 0,18412977 0,18688368 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,18412977 0,18680607 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,18601665 0,18864204 ! tube morphogenesis GO:0035239 194 89 0,000 0,18601665 0,18856376 ! cellular defense response GO:0006968 123 89 0,000 0,18601665 0,18848556 ! regulation of neurological system process GO:0031644 175 89 0,000 0,18601665 0,18840741 ! response to inorganic substance GO:0010035 173 90 0,000 0,18789922 0,19023531 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,18789922 0,1901565 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,18789922 0,19007776 ! response to unfolded protein GO:0006986 139 90 0,000 0,18789922 0,18999909 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,18789922 0,18992048 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,18977749 0,19173963 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,18977749 0,19166036 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,19165148 0,19347296 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,19165148 0,19339304 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,19352117 0,1951991 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,19352117 0,19511854 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,19352117 0,19503805 ! vitamin metabolic process GO:0006766 153 93 0,000 0,19352117 0,19495762 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,1953866 0,19675576 ! female pregnancy GO:0007565 166 94 0,000 0,1953866 0,19667469 ! sterol metabolic process GO:0016125 166 94 0,000 0,1953866 0,19659369 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,1953866 0,19651275 ! regulation of defense response GO:0031347 171 95 0,000 0,19724777 0,198303 ! nucleosome organization GO:0034728 143 95 0,000 0,19724777 0,19822143 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,19724777 0,19813992 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,19724777 0,19805849 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,19724777 0,19797711 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,19724777 0,19789581 ! response to protein stimulus GO:0051789 158 96 0,000 0,19910468 0,19967682 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,20095735 0,20145211 ! transcription initiation GO:0006352 171 97 0,000 0,20095735 0,20136948 ! regulation of protein localization GO:0032880 188 97 0,000 0,20095735 0,20128692 ! forebrain development GO:0030900 210 98 0,000 0,20280578 0,20305514 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,20280578 0,20297195 ! mRNA transport GO:0051028 185 100 0,000 0,20648999 0,20657455 ! hormone metabolic process GO:0042445 171 100 0,000 0,20648999 0,20648999