pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1114-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 209 95 10,000 1,123E-12 2,701E-09 ! interphase GO:0051325 213 98 10,000 1,592E-12 1,915E-09 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 8,000 7,508E-12 6,021E-09 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 7,000 5,024E-11 3,022E-08 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 4,000 1,29E-10 6,207E-08 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 4,000 5,76E-10 2,31E-07 ! auditory receptor cell differentiation GO:0042491 32 16 4,000 9,757E-09 3,353E-06 ! lung development GO:0030324 144 67 6,000 3,376E-08 1,015E-05 ! inner ear receptor cell differentiation GO:0060113 37 20 4,000 3,41E-08 9,116E-06 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 3,000 3,457E-08 8,317E-06 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 4,000 4,459E-08 9,752E-06 ! respiratory tube development GO:0030323 150 70 6,000 4,598E-08 9,219E-06 ! respiratory system development GO:0060541 153 72 6,000 5,605E-08 1,037E-05 ! mechanoreceptor differentiation GO:0042490 40 22 4,000 5,748E-08 9,878E-06 ! negative regulation of phosphorylation GO:0042326 47 24 4,000 9,206E-08 1,477E-05 ! response to hypoxia GO:0001666 171 81 6,000 1,277E-07 1,92E-05 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 4,000 1,414E-07 2,001E-05 GO:0045936|negative regulation of phosphate metabolic process, ! response to oxygen levels GO:0070482 176 83 6,000 1,512E-07 2,021E-05 ! cell cycle arrest GO:0007050 213 100 6,000 5,449E-07 6,9E-05 ! positive regulation of cell motion GO:0051272 146 64 5,000 6,421E-07 7,725E-05 ! cell cycle checkpoint GO:0000075 137 69 5,000 1,007E-06 1,153E-04 ! mitotic cell cycle checkpoint GO:0007093 76 38 4,000 1,03E-06 1,127E-04 ! positive regulation of glycolysis GO:0045821 14 5 2,000 1,063E-06 1,112E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 2,288E-06 2,294E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 2,441E-06 2,349E-04 ! negative regulation of growth GO:0045926 155 84 5,000 3,219E-06 2,979E-04 ! N-terminal protein amino acid acetylation GO:0006474 13 7 2,000 3,694E-06 3,292E-04 ! inner ear development GO:0048839 79 50 4,000 4,153E-06 3,568E-04 ! response to UV GO:0009411 104 53 4,000 5,56E-06 4,613E-04 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 3,000 5,864E-06 4,703E-04 ! positive regulation of cell migration GO:0030335 126 57 4,000 7,989E-06 6,2E-04 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 8,075E-06 6,072E-04 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 8,805E-06 6,419E-04 ! regulation of glycolysis GO:0006110 21 9 2,000 8,805E-06 6,231E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 8,805E-06 6,053E-04 ! DNA damage response, signal transduction GO:0042770 128 60 4,000 1,03E-05 6,885E-04 ! cellular response to extracellular stimulus GO:0031668 48 29 3,000 1,085E-05 7,054E-04 ! ear development GO:0043583 103 62 4,000 1,211E-05 7,669E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 1,253E-05 7,732E-04 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 2,000 1,253E-05 7,539E-04 GO:0043470|regulation of carbohydrate catabolic process, ! steroid hormone receptor signaling pathway GO:0030518 129 63 4,000 1,311E-05 7,691E-04 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 1,717E-05 9,838E-04 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 1,717E-05 9,609E-04 ! peptide or protein amino-terminal blocking GO:0018409 21 11 2,000 1,717E-05 9,391E-04 ! negative regulation of cell growth GO:0030308 132 67 4,000 1,773E-05 9,481E-04 ! DNA damage checkpoint GO:0000077 71 33 3,000 1,841E-05 9,631E-04 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 4,000 1,907E-05 9,761E-04 ! negative regulation of cell size GO:0045792 134 69 4,000 2,048E-05 1,026E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 2,282E-05 1,12E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 2,282E-05 1,098E-03 ! histone acetylation GO:0016573 26 12 2,000 2,282E-05 1,076E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 2,282E-05 1,056E-03 ! DNA integrity checkpoint GO:0031570 75 36 3,000 2,621E-05 1,19E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 2,000 2,956E-05 1,317E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 2,000 2,956E-05 1,293E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 3,749E-05 1,611E-03 ! regulation of erythrocyte differentiation GO:0045646 44 14 2,000 3,749E-05 1,582E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 3,749E-05 1,555E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 3,952E-05 1,612E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 4,459E-05 1,788E-03 GO:0045937|positive regulation of phosphate metabolic process, ! G1/S transition checkpoint GO:0031575 40 15 2,000 4,67E-05 1,842E-03 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 4,73E-05 1,836E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 5,351E-05 2,044E-03 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 5,727E-05 2,153E-03 ! G1 phase of mitotic cell cycle GO:0000080 35 16 2,000 5,727E-05 2,12E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 6,93E-05 2,526E-03 ! regulation of gene-specific transcription GO:0032583 96 46 3,000 6,997E-05 2,513E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 8,282E-05 2,93E-03 ! patterning of blood vessels GO:0001569 39 18 2,000 8,287E-05 2,89E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 8,287E-05 2,848E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 8,638E-05 2,927E-03 ! histone modification GO:0016570 91 50 3,000 9,73E-05 3,251E-03 ! positive regulation of angiogenesis GO:0045766 44 19 2,000 9,806E-05 3,232E-03 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 2,000 9,806E-05 3,188E-03 ! G1 phase GO:0051318 40 19 2,000 9,806E-05 3,146E-03 ! positive regulation of growth GO:0045927 90 52 3,000 1,135E-04 3,594E-03 ! covalent chromatin modification GO:0016569 101 52 3,000 1,135E-04 3,548E-03 ! protein amino acid acetylation GO:0006473 39 20 2,000 1,15E-04 3,546E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 1,15E-04 3,501E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,15E-04 3,458E-03 ! Golgi vesicle transport GO:0048193 207 99 4,000 1,162E-04 3,451E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 1,518E-04 4,453E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 1,767E-04 5,123E-03 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 2,013E-04 5,765E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 2,013E-04 5,697E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 2,013E-04 5,631E-03 ! protein tetramerization GO:0051262 52 24 2,000 2,013E-04 5,566E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 2,249E-04 6,149E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,249E-04 6,08E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 2,249E-04 6,012E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 2,249E-04 5,946E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 2,249E-04 5,882E-03 ! valine metabolic process GO:0006573 10 5 1,000 2,249E-04 5,818E-03 ! mRNA transcription GO:0009299 9 5 1,000 2,249E-04 5,756E-03 ! response to food GO:0032094 6 5 1,000 2,249E-04 5,696E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 2,249E-04 5,637E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,249E-04 5,578E-03 ! negative regulation of interleukin-6 production GO:0032715 5 5 1,000 2,249E-04 5,522E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 2,249E-04 5,466E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 2,249E-04 5,411E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,249E-04 5,358E-03 ! stem cell division GO:0017145 11 5 1,000 2,249E-04 5,305E-03 GO:0048103|somatic stem cell division, ! regulation of homeostatic process GO:0032844 134 62 3,000 2,254E-04 5,266E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 2,279E-04 5,273E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 2,279E-04 5,223E-03 ! cellular response to nutrient levels GO:0031669 41 25 2,000 2,279E-04 5,173E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 2,568E-04 5,773E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 2,568E-04 5,72E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 2,568E-04 5,667E-03 ! protein amino acid acylation GO:0043543 55 27 2,000 2,878E-04 6,296E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 3,041E-04 6,591E-03 ! activation of MAPK activity GO:0000187 115 67 3,000 3,041E-04 6,533E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 3,212E-04 6,84E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 3,212E-04 6,78E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 3,219E-04 6,735E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 3,363E-04 6,975E-03 ! male meiosis GO:0007140 7 6 1,000 3,363E-04 6,916E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 3,363E-04 6,857E-03 ! positive regulation of neuroblast proliferation GO:0002052 13 6 1,000 3,363E-04 6,799E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 3,363E-04 6,743E-03 ! male sex determination GO:0030238 15 6 1,000 3,363E-04 6,687E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 3,363E-04 6,632E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 3,363E-04 6,578E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 3,363E-04 6,525E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 3,954E-04 7,61E-03 ! regulation of caspase activity GO:0043281 122 72 3,000 4,007E-04 7,651E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 4,007E-04 7,591E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 4,007E-04 7,532E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 4,448E-04 8,297E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 4,693E-04 8,686E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 4,693E-04 8,62E-03 ! mRNA stabilization GO:0048255 18 7 1,000 4,693E-04 8,555E-03 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 4,693E-04 8,49E-03 GO:0031958|corticosteroid receptor signaling pathway, ! oxaloacetate metabolic process GO:0006107 10 7 1,000 4,693E-04 8,427E-03 ! positive regulation of heart rate GO:0010460 10 7 1,000 4,693E-04 8,364E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 1,000 4,693E-04 8,303E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 4,693E-04 8,242E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 4,693E-04 8,183E-03 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 1,000 4,693E-04 8,124E-03 ! regulation of interleukin-1 beta production GO:0032651 10 7 1,000 4,693E-04 8,066E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 4,693E-04 8,009E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 4,693E-04 7,952E-03 ! oxygen homeostasis GO:0032364 12 7 1,000 4,693E-04 7,897E-03 ! response to tumor cell GO:0002347 13 7 1,000 4,693E-04 7,842E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 4,693E-04 7,788E-03 ! dopamine biosynthetic process GO:0042416 18 7 1,000 4,693E-04 7,734E-03 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 1,000 4,693E-04 7,682E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 4,796E-04 7,797E-03 ! regulation of catabolic process GO:0009894 161 76 3,000 4,924E-04 7,951E-03 ! positive regulation of gene-specific transcription GO:0043193 65 33 2,000 5,257E-04 8,433E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 5,703E-04 9,087E-03 ! succinate metabolic process GO:0006105 14 8 1,000 6,238E-04 9,874E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 6,238E-04 9,81E-03 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 1,000 6,238E-04 9,746E-03 ! hemoglobin metabolic process GO:0020027 13 8 1,000 6,238E-04 9,683E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 6,238E-04 9,621E-03 ! ER overload response GO:0006983 12 8 1,000 6,238E-04 9,56E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 6,238E-04 9,499E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 6,238E-04 9,44E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 6,238E-04 9,381E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 6,238E-04 9,322E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 6,238E-04 9,265E-03 ! regulation of interleukin-1 production GO:0032652 13 8 1,000 6,238E-04 9,208E-03 ! behavioral response to nicotine GO:0035095 12 8 1,000 6,238E-04 9,152E-03 ! negative regulation of hydrolase activity GO:0051346 62 35 2,000 6,263E-04 9,132E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 6,808E-04 9,868E-03 ! tissue remodeling GO:0048771 76 37 2,000 7,383E-04 0,01063731 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 7,383E-04 0,01057399 ! mitochondrion organization GO:0007005 148 86 3,000 7,855E-04 0,01118221 ! carbohydrate homeostasis GO:0033500 53 38 2,000 7,988E-04 0,01130571 GO:0042593|glucose homeostasis, ! regulation of developmental growth GO:0048638 15 9 1,000 7,995E-04 0,01124943 ! associative learning GO:0008306 20 9 1,000 7,995E-04 0,01118403 ! induction of positive chemotaxis GO:0050930 15 9 1,000 7,995E-04 0,01111938 ! keratinocyte proliferation GO:0043616 14 9 1,000 7,995E-04 0,01105548 ! phosphagen metabolic process GO:0006599 12 9 1,000 7,995E-04 0,0109923 GO:0006600|creatine metabolic process, ! protein heterooligomerization GO:0051291 16 9 1,000 7,995E-04 0,01092985 ! gas homeostasis GO:0033483 16 9 1,000 7,995E-04 0,0108681 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 7,995E-04 0,01080704 ! positive regulation of protein modification process GO:0031401 136 88 3,000 8,562E-04 0,01150814 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 9,291E-04 0,0124183 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 9,963E-04 0,01324325 ! positive regulation of heart contraction GO:0045823 16 10 1,000 9,963E-04 0,01317048 ! lung alveolus development GO:0048286 26 10 1,000 9,963E-04 0,01309851 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 9,963E-04 0,01302732 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 9,963E-04 0,0129569 ! regulation of bone resorption GO:0045124 25 10 1,000 9,963E-04 0,01288724 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 9,963E-04 0,01281833 ! response to nicotine GO:0035094 20 10 1,000 9,963E-04 0,01275015 ! localization within membrane GO:0051668 20 10 1,000 9,963E-04 0,01268268 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 1,072E-03 0,01357485 ! blood vessel remodeling GO:0001974 29 11 1,000 1,214E-03 0,01529067 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,214E-03 0,01521103 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of catecholamine secretion GO:0050433 20 11 1,000 1,214E-03 0,01513222 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,214E-03 0,01505422 ! substrate-bound cell migration GO:0006929 13 11 1,000 1,214E-03 0,01497701 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 1,214E-03 0,0149006 ! negative regulation of tumor necrosis factor production GO:0032720 15 11 1,000 1,214E-03 0,01482496 ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,214E-03 0,01475009 ! regulation of embryonic development GO:0045995 27 11 1,000 1,214E-03 0,01467597 ! JAK-STAT cascade GO:0007259 71 44 2,000 1,228E-03 0,01477427 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 1,231E-03 0,01473144 ! regulation of JAK-STAT cascade GO:0046425 70 45 2,000 1,311E-03 0,01561829 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 1,311E-03 0,01554135 ! response to insulin stimulus GO:0032868 95 46 2,000 1,398E-03 0,01648655 ! positive regulation of blood pressure GO:0045777 17 12 1,000 1,452E-03 0,01704215 ! virus-host interaction GO:0019048 29 12 1,000 1,452E-03 0,01695942 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 1,452E-03 0,01687749 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of cell growth GO:0030307 22 12 1,000 1,452E-03 0,01679635 ! histone methylation GO:0016571 26 12 1,000 1,452E-03 0,01671599 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 1,452E-03 0,01663639 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,452E-03 0,01655754 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,452E-03 0,01647944 ! activation of caspase activity GO:0006919 84 48 2,000 1,582E-03 0,01786599 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 1,582E-03 0,01778251 ! regulation of chemokine production GO:0032642 18 13 1,000 1,711E-03 0,0191438 ! response to X-ray GO:0010165 25 13 1,000 1,711E-03 0,01905518 ! regulation of cellular pH GO:0030641 22 13 1,000 1,711E-03 0,01896736 ! regulation of mRNA stability GO:0043488 31 13 1,000 1,711E-03 0,01888036 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 1,711E-03 0,01879415 ! embryonic placenta development GO:0001892 23 13 1,000 1,711E-03 0,01870872 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 1,885E-03 0,02051708 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of S phase GO:0033261 23 14 1,000 1,99E-03 0,02156248 ! regulation of heart rate GO:0002027 24 14 1,000 1,99E-03 0,02146579 ! negative regulation of caspase activity GO:0043154 22 14 1,000 1,99E-03 0,02136996 ! response to gamma radiation GO:0010332 28 14 1,000 1,99E-03 0,02127498 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 1,99E-03 0,02118085 ! regulation of RNA stability GO:0043487 32 14 1,000 1,99E-03 0,02108754 ! regulation of angiogenesis GO:0045765 114 52 2,000 1,993E-03 0,0210314 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 1,993E-03 0,02093956 ! positive regulation of cell size GO:0045793 27 15 1,000 2,288E-03 0,02393925 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 2,288E-03 0,02383562 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 2,288E-03 0,02373288 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 2,288E-03 0,02363102 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,288E-03 0,02353003 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 2,288E-03 0,0234299 ! muscle maintenance GO:0046716 26 15 1,000 2,288E-03 0,02333062 ! dopamine metabolic process GO:0042417 35 15 1,000 2,288E-03 0,02323218 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 2,288E-03 0,02313457 ! positive regulation of caspase activity GO:0043280 95 55 2,000 2,341E-03 0,02357 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 2,000 2,341E-03 0,02347179 ! heart morphogenesis GO:0003007 97 55 2,000 2,341E-03 0,0233744 ! regulation of bone remodeling GO:0046850 137 57 2,000 2,593E-03 0,02578186 ! negative regulation of inflammatory response GO:0050728 22 16 1,000 2,607E-03 0,02581447 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 2,607E-03 0,02570868 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 2,607E-03 0,02560374 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,607E-03 0,02549966 ! regulation of tissue remodeling GO:0034103 140 58 2,000 2,725E-03 0,02654531 ! regulation of endocytosis GO:0030100 91 58 2,000 2,725E-03 0,02643827 ! heart looping GO:0001947 30 17 1,000 2,946E-03 0,02846215 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 2,946E-03 0,0283483 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 2,946E-03 0,02823536 ! neural crest cell migration GO:0001755 37 17 1,000 2,946E-03 0,02812331 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 2,946E-03 0,02801215 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 2,946E-03 0,02790187 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 2,946E-03 0,02779245 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 3,001E-03 0,02820759 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 3,146E-03 0,02944867 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 3,303E-03 0,03080634 ! memory GO:0007613 31 18 1,000 3,303E-03 0,03068739 ! negative regulation of defense response GO:0031348 25 19 1,000 3,681E-03 0,034059 ! skin development GO:0043588 36 19 1,000 3,681E-03 0,03392851 ! lipid phosphorylation GO:0046834 35 19 1,000 3,681E-03 0,03379901 ! cellular response to unfolded protein GO:0034620 33 19 1,000 3,681E-03 0,03367049 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 42 19 1,000 3,681E-03 0,03354296 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 3,681E-03 0,03341638 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 3,681E-03 0,03329075 ! estrogen receptor signaling pathway GO:0030520 38 19 1,000 3,681E-03 0,03316607 ! response to alkaloid GO:0043279 38 20 1,000 4,077E-03 0,036599 ! cellular response to starvation GO:0009267 33 20 1,000 4,077E-03 0,03646295 ! negative regulation of T cell activation GO:0050868 40 20 1,000 4,077E-03 0,0363279 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 4,077E-03 0,03619385 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 4,101E-03 0,03627284 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 4,492E-03 0,03958666 ! cell aging GO:0007569 44 21 1,000 4,492E-03 0,03944219 ! positive regulation of locomotion GO:0040017 39 21 1,000 4,492E-03 0,03929876 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! B cell activation GO:0042113 160 71 2,000 4,825E-03 0,042062 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 4,926E-03 0,04278256 ! regulation of chemotaxis GO:0050920 40 22 1,000 4,926E-03 0,04262867 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 4,926E-03 0,04247588 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 4,926E-03 0,04232418 ! apoptotic nuclear changes GO:0030262 32 22 1,000 4,926E-03 0,04217356 ! positive regulation of B cell activation GO:0050871 38 22 1,000 4,926E-03 0,042024 ! positive regulation of DNA replication GO:0045740 43 23 1,000 5,378E-03 0,04572055 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 5,378E-03 0,04555957 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 5,378E-03 0,04539971 ! response to ethanol GO:0045471 46 23 1,000 5,378E-03 0,04524097 ! vesicle targeting GO:0006903 43 23 1,000 5,378E-03 0,04508333 ! sex determination GO:0007530 47 23 1,000 5,378E-03 0,04492679 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 5,378E-03 0,04477134 ! regulation of interleukin-6 production GO:0032675 29 23 1,000 5,378E-03 0,04461695 ! negative regulation of cytokine production GO:0001818 40 23 1,000 5,378E-03 0,04446363 ! regulation of transcription factor activity GO:0051090 126 74 2,000 5,416E-03 0,04462547 GO:0090046|regulation of transcription regulator activity, ! regulation of vesicle-mediated transport GO:0060627 119 75 2,000 5,622E-03 0,04616602 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 5,848E-03 0,04786108 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 5,848E-03 0,04769884 ! regulation of transmembrane transport GO:0034762 38 24 1,000 5,848E-03 0,04753769 ! regulation of behavior GO:0050795 43 24 1,000 5,848E-03 0,04737763 ! regulation of tumor necrosis factor production GO:0032680 34 24 1,000 5,848E-03 0,04721865 ! regulation of amine transport GO:0051952 40 24 1,000 5,848E-03 0,04706073 ! protein oligomerization GO:0051259 139 78 2,000 6,269E-03 0,05027372 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 6,337E-03 0,05065466 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 6,337E-03 0,05048692 ! protein amino acid alkylation GO:0008213 53 25 1,000 6,337E-03 0,0503203 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 1,000 6,337E-03 0,05015477 ! sperm motility GO:0030317 31 25 1,000 6,337E-03 0,04999033 ! negative regulation of DNA replication GO:0008156 42 25 1,000 6,337E-03 0,04982696 ! response to starvation GO:0042594 42 25 1,000 6,337E-03 0,04966466 ! neural crest cell development GO:0014032 54 25 1,000 6,337E-03 0,04950341 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 1,000 6,337E-03 0,04934321 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 6,337E-03 0,04918404 ! somitogenesis GO:0001756 43 25 1,000 6,337E-03 0,04902589 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 6,493E-03 0,05007468 ! cellular response to oxidative stress GO:0034599 39 26 1,000 6,844E-03 0,05260754 ! response to estradiol stimulus GO:0032355 40 26 1,000 6,844E-03 0,05244 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 6,844E-03 0,05227353 ! T cell activation GO:0042110 168 81 2,000 6,958E-03 0,05297495 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 7,368E-03 0,05592445 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 7,368E-03 0,05574859 ! fat cell differentiation GO:0045444 50 27 1,000 7,368E-03 0,05557383 ! mitochondrial membrane organization GO:0007006 57 27 1,000 7,368E-03 0,05540016 ! base-excision repair GO:0006284 41 27 1,000 7,368E-03 0,05522757 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 7,368E-03 0,05505606 ! regulation of ligase activity GO:0051340 142 84 2,000 7,69E-03 0,05728218 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 7,91E-03 0,05874164 ! tube morphogenesis GO:0035239 176 86 2,000 8,203E-03 0,06072433 ! regulation of pH GO:0006885 43 29 1,000 8,47E-03 0,0625106 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 8,47E-03 0,06231943 ! catechol metabolic process GO:0009712 54 29 1,000 8,47E-03 0,06212943 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to organic cyclic substance GO:0014070 55 29 1,000 8,47E-03 0,06194059 ! regulation of DNA binding GO:0051101 155 88 2,000 8,735E-03 0,06368481 ! regulation of cell adhesion GO:0030155 212 89 2,000 9,008E-03 0,06548078 ! phenol metabolic process GO:0018958 55 30 1,000 9,047E-03 0,06556058 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 9,047E-03 0,06536371 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 9,047E-03 0,06516801 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 9,047E-03 0,06497347 ! neurotransmitter secretion GO:0007269 48 30 1,000 9,047E-03 0,0647801 ! regulation of cell cycle process GO:0010564 149 90 2,000 9,287E-03 0,06630344 ! collagen metabolic process GO:0032963 45 31 1,000 9,64E-03 0,06862381 ! ovulation cycle process GO:0022602 49 31 1,000 9,64E-03 0,06842138 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 9,64E-03 0,06822014 GO:0043433|negative regulation of transcription factor activity, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 9,64E-03 0,06802008 ! iron ion homeostasis GO:0055072 54 31 1,000 9,64E-03 0,0678212 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,01015248 0,07121532 ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 0,01025114 0,07169837 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01025114 0,07149055 ! ovulation cycle GO:0042698 51 32 1,000 0,01025114 0,07128393 ! female pregnancy GO:0007565 164 94 2,000 0,01045107 0,07246475 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 0,01087858 0,07521228 ! establishment of vesicle localization GO:0051650 61 33 1,000 0,01087858 0,07499677 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01152258 0,07920952 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01152258 0,07898385 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,01152258 0,07875947 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 0,01152258 0,07853635 ! placenta development GO:0001890 53 34 1,000 0,01152258 0,0783145 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01152258 0,07809389 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01218296 0,08233767 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01218296 0,08210703 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01218296 0,08187768 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01218296 0,08164961 ! vesicle localization GO:0051648 64 35 1,000 0,01218296 0,0814228 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01285956 0,08570664 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01285956 0,08546988 ! embryonic organ development GO:0048568 57 36 1,000 0,01285956 0,08523443 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01285956 0,08500027 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,0135522 0,08933313 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,0135522 0,08908905 ! regulation of protein stability GO:0031647 73 37 1,000 0,0135522 0,0888463 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01426072 0,09323721 ! nucleus organization GO:0006997 67 38 1,000 0,01426072 0,09298454 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01426072 0,09273323 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 77 39 1,000 0,01498496 0,09718006 ! segmentation GO:0035282 67 39 1,000 0,01498496 0,09691883 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01498496 0,09665899 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,01572474 0,10115969 ! negative regulation of binding GO:0051100 72 40 1,000 0,01572474 0,10088993 ! mesenchymal cell development GO:0014031 87 40 1,000 0,01572474 0,10062161 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cellular amide metabolic process GO:0043603 67 41 1,000 0,01647991 0,10517418 ! gliogenesis GO:0042063 88 41 1,000 0,01647991 0,10489594 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,01647991 0,10461917 ! T cell differentiation GO:0030217 81 41 1,000 0,01647991 0,10434386 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,01647991 0,10406999 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,01647991 0,10379756 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01725031 0,10836616 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,01803577 0,11300535 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,01883613 0,11771359 ! double-strand break repair GO:0006302 81 44 1,000 0,01883613 0,11740863 ! biopolymer methylation GO:0043414 84 44 1,000 0,01883613 0,11710525 ! B cell differentiation GO:0030183 107 44 1,000 0,01883613 0,11680343 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,02048094 0,12667646 ! response to calcium ion GO:0051592 81 47 1,000 0,02132507 0,13155929 ! endosome transport GO:0016197 108 47 1,000 0,02132507 0,13122282 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02132507 0,13088807 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,02132507 0,13055502 ! methylation GO:0032259 90 47 1,000 0,02132507 0,13022366 ! mitochondrial transport GO:0006839 82 48 1,000 0,02218348 0,13512267 ! cellular component disassembly GO:0022411 86 48 1,000 0,02218348 0,13478146 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,02218348 0,13444196 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,02218348 0,13410416 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,02218348 0,13376806 ! regulation of action potential GO:0001508 95 49 1,000 0,02305601 0,13868193 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0236808 0,14208479 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0236808 0,14173135 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0236808 0,14137965 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0236808 0,14102971 ! neuron fate determination GO:0048664 7 5 0,000 0,0236808 0,14068148 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0236808 0,14033498 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0236808 0,13999017 ! polyol transport GO:0015791 12 5 0,000 0,0236808 0,13964706 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0236808 0,13930563 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0236808 0,13896586 ! response to superoxide GO:0000303 10 5 0,000 0,0236808 0,13862774 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0236808 0,13829126 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0236808 0,13795642 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0236808 0,13762319 ! female meiosis GO:0007143 7 5 0,000 0,0236808 0,13729157 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0236808 0,13696154 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0236808 0,1366331 ! cobalt ion transport GO:0006824 11 5 0,000 0,0236808 0,13630622 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0236808 0,13598091 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0236808 0,13565714 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0236808 0,13533492 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0236808 0,13501422 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0236808 0,13469504 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0236808 0,13437736 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0236808 0,13406118 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0236808 0,13374648 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0236808 0,13343326 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0236808 0,1331215 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0236808 0,13281119 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0236808 0,13250233 ! negative chemotaxis GO:0050919 14 5 0,000 0,0236808 0,1321949 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0236808 0,13188889 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0236808 0,1315843 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0236808 0,13128111 ! behavioral response to pain GO:0048266 9 5 0,000 0,0236808 0,13097931 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0236808 0,1306789 ! Notch receptor processing GO:0007220 8 5 0,000 0,0236808 0,13037986 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0236808 0,13008219 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0236808 0,12978588 ! micturition GO:0060073 9 5 0,000 0,0236808 0,12949091 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0236808 0,12919728 ! copulation GO:0007620 9 5 0,000 0,0236808 0,12890498 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0236808 0,128614 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0236808 0,12832433 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0236808 0,12803596 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0236808 0,12774888 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0236808 0,12746309 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0236808 0,12717857 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0236808 0,12689532 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0236808 0,12661334 ! grooming behavior GO:0007625 6 5 0,000 0,0236808 0,1263326 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0236808 0,1260531 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0236808 0,12577484 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0236808 0,1254978 ! response to protozoan GO:0001562 10 5 0,000 0,0236808 0,12522198 ! lymph vessel development GO:0001945 10 5 0,000 0,0236808 0,12494737 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0236808 0,12467396 ! endochondral ossification GO:0001958 16 5 0,000 0,0236808 0,12440175 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0236808 0,12413072 ! parathyroid gland development GO:0060017 13 5 0,000 0,0236808 0,12386087 ! anagen GO:0042640 6 5 0,000 0,0236808 0,12359219 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0236808 0,12332468 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0236808 0,12305832 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0236808 0,12279311 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0236808 0,12252903 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0236808 0,1222661 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0236808 0,12200428 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0236808 0,12174359 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0236808 0,12148401 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0236808 0,12122553 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0236808 0,12096815 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0236808 0,12071187 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0236808 0,12045666 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0236808 0,12020253 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0236808 0,11994948 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0236808 0,11969748 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,0236808 0,11944654 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0236808 0,11919665 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0236808 0,11894781 ! histidine catabolic process GO:0006548 6 5 0,000 0,0236808 0,1187 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0236808 0,11845322 ! microvillus organization GO:0032528 7 5 0,000 0,0236808 0,11820747 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0236808 0,11796273 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0236808 0,11771901 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0236808 0,11747629 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0236808 0,11723457 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0236808 0,11699384 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0236808 0,1167541 ! polyol catabolic process GO:0046174 7 5 0,000 0,0236808 0,11651534 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0236808 0,11627755 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0236808 0,11604073 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0236808 0,11580488 ! muscle cell migration GO:0014812 8 5 0,000 0,0236808 0,11556998 ! mitochondrial fission GO:0000266 8 5 0,000 0,0236808 0,11533603 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0236808 0,11510303 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0236808 0,11487097 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0236808 0,11463984 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0236808 0,11440964 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0236808 0,11418036 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0236808 0,113952 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0236808 0,11372455 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0236808 0,11349801 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0236808 0,11327237 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0236808 0,11304762 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0236808 0,11282376 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0236808 0,11260079 ! forebrain neuron development GO:0021884 13 5 0,000 0,0236808 0,1123787 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0236808 0,11215748 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0236808 0,11193713 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0236808 0,11171765 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0236808 0,11149902 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0236808 0,11128125 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0236808 0,11106433 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0236808 0,11084825 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0236808 0,11063301 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0236808 0,11041861 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0236808 0,11020503 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0236808 0,10999228 ! basic amino acid transport GO:0015802 11 5 0,000 0,0236808 0,10978035 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0236808 0,10956923 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,0236808 0,10935893 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0236808 0,10914943 ! depyrimidination GO:0045008 10 5 0,000 0,0236808 0,10894073 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0236808 0,10873283 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0236808 0,10852572 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0236808 0,10831939 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0236808 0,10811385 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,0236808 0,10790909 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0236808 0,10770511 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0236808 0,10750189 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0236808 0,10729944 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0236808 0,10709775 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0236808 0,10689681 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0236808 0,10669663 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0236808 0,1064972 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0236808 0,10629851 ! response to arsenic GO:0046685 10 5 0,000 0,0236808 0,10610056 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0236808 0,10590335 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0236808 0,10570687 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0236808 0,10551111 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0236808 0,10531608 ! response to cadmium ion GO:0046686 7 5 0,000 0,0236808 0,10512177 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0236808 0,10492818 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0236808 0,1047353 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0236808 0,10454312 ! decidualization GO:0046697 11 5 0,000 0,0236808 0,10435165 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0236808 0,10416088 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0236808 0,1039708 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0236808 0,10378142 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0236808 0,10359273 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0236808 0,10340472 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0236808 0,10321739 ! neural tube patterning GO:0021532 7 5 0,000 0,0236808 0,10303074 ! embryonic cleavage GO:0040016 6 5 0,000 0,0236808 0,10284477 ! peroxisome fission GO:0016559 5 5 0,000 0,0236808 0,10265946 ! histone demethylation GO:0016577 10 5 0,000 0,0236808 0,10247482 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0236808 0,10229085 ! mitotic recombination GO:0006312 9 5 0,000 0,0236808 0,10210753 ! metaphase plate congression GO:0051310 7 5 0,000 0,0236808 0,10192487 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0236808 0,10174286 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,0236808 0,1015615 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0236808 0,10138078 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0236808 0,10120071 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0236808 0,10102128 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0236808 0,10084248 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0236808 0,10066431 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0236808 0,10048677 ! plasminogen activation GO:0031639 5 5 0,000 0,0236808 0,10030986 ! B cell homeostasis GO:0001782 13 5 0,000 0,0236808 0,10013357 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0236808 0,0999579 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0236808 0,09978284 ! metaphase GO:0051323 8 5 0,000 0,0236808 0,09960839 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0236808 0,09943456 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0236808 0,09926133 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0236808 0,0990887 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0236808 0,09891667 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0236808 0,09874524 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0236808 0,0985744 ! response to redox state GO:0051775 5 5 0,000 0,0236808 0,09840415 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0236808 0,09823448 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0236808 0,09806541 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0236808 0,09789691 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0236808 0,09772899 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0236808 0,09756165 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0236808 0,09739487 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0236808 0,09722867 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0236808 0,09706303 ! striatum development GO:0021756 9 5 0,000 0,0236808 0,09689796 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0236808 0,09673345 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0236808 0,09656949 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0236808 0,09640609 ! glial cell migration GO:0008347 11 5 0,000 0,0236808 0,09624324 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0236808 0,09608095 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0236808 0,09591919 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0236808 0,09575798 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0236808 0,09559732 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0236808 0,09543719 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0236808 0,09527759 ! neuroprotection GO:0043526 6 5 0,000 0,0236808 0,09511853 ! neural plate development GO:0001840 8 5 0,000 0,0236808 0,09496 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0236808 0,094802 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0236808 0,09464452 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0236808 0,09448756 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0236808 0,09433113 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0236808 0,09417521 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0236808 0,0940198 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0236808 0,09386491 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0236808 0,09371053 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0236808 0,09355665 ! spindle assembly GO:0051225 6 5 0,000 0,0236808 0,09340328 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0236808 0,09325041 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0236808 0,09309804 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0236808 0,09294617 ! drug metabolic process GO:0017144 6 5 0,000 0,0236808 0,09279479 ! phospholipid scrambling GO:0017121 8 5 0,000 0,0236808 0,0926439 ! organ regeneration GO:0031100 7 5 0,000 0,0236808 0,09249351 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0236808 0,0923436 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0236808 0,09219418 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0236808 0,09204524 ! regulation of ossification GO:0030278 117 50 1,000 0,02394252 0,09291242 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,02394252 0,09276281 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,02394252 0,09261367 ! positive regulation of binding GO:0051099 78 51 1,000 0,02484284 0,09594203 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,02484284 0,09578827 ! chromatin remodeling GO:0006338 109 51 1,000 0,02484284 0,09563501 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,02484284 0,09548224 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,02484284 0,09532996 ! regulation of cell shape GO:0008360 125 51 1,000 0,02484284 0,09517816 ! cartilage development GO:0051216 90 52 1,000 0,02575684 0,09852298 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,02668435 0,10190881 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,02762524 0,1053349 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,02762524 0,10516823 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,02762524 0,10500209 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0283497 0,10758577 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0283497 0,10741634 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0283497 0,10724745 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0283497 0,10707909 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0283497 0,10691125 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0283497 0,10674394 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0283497 0,10657715 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0283497 0,10641089 ! sleep GO:0030431 13 6 0,000 0,0283497 0,10624514 ! response to oxygen radical GO:0000305 11 6 0,000 0,0283497 0,1060799 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0283497 0,10591518 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0283497 0,10575097 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0283497 0,10558727 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0283497 0,10542408 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0283497 0,10526139 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0283497 0,1050992 ! forebrain regionalization GO:0021871 8 6 0,000 0,0283497 0,1049375 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0283497 0,10477631 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0283497 0,10461561 ! response to zinc ion GO:0010043 9 6 0,000 0,0283497 0,1044554 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0283497 0,10429569 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,0283497 0,10413646 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0283497 0,10397771 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0283497 0,10381945 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0283497 0,10366167 ! malate metabolic process GO:0006108 11 6 0,000 0,0283497 0,10350437 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0283497 0,10334754 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0283497 0,10319119 ! protein refolding GO:0042026 15 6 0,000 0,0283497 0,10303531 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0283497 0,10287991 ! opsonization GO:0008228 8 6 0,000 0,0283497 0,10272497 ! mating behavior GO:0007617 7 6 0,000 0,0283497 0,10257049 ! neuron remodeling GO:0016322 15 6 0,000 0,0283497 0,10241648 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0283497 0,10226294 ! equilibrioception GO:0050957 14 6 0,000 0,0283497 0,10210985 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0283497 0,10195722 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0283497 0,10180504 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0283497 0,10165332 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0283497 0,10150205 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0283497 0,10135123 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0283497 0,10120086 ! toxin metabolic process GO:0009404 11 6 0,000 0,0283497 0,10105093 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0283497 0,10090145 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0283497 0,1007524 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0283497 0,1006038 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0283497 0,10045564 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,0283497 0,10030791 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0283497 0,10016061 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0283497 0,10001375 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0283497 0,09986732 ! thymic T cell selection GO:0045061 12 6 0,000 0,0283497 0,09972131 ! protein lipoylation GO:0009249 10 6 0,000 0,0283497 0,09957573 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0283497 0,09943058 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0283497 0,09928585 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0283497 0,09914154 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0283497 0,09899765 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0283497 0,09885417 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0283497 0,09871111 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,0283497 0,09856847 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0283497 0,09842623 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0283497 0,09828441 ! hyperosmotic response GO:0006972 9 6 0,000 0,0283497 0,09814299 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0283497 0,09800198 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0283497 0,09786137 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0283497 0,09772117 ! urea metabolic process GO:0019627 7 6 0,000 0,0283497 0,09758137 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0283497 0,09744197 ! neutrophil activation GO:0042119 8 6 0,000 0,0283497 0,09730296 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0283497 0,09716436 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0283497 0,09702614 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0283497 0,09688832 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0283497 0,09675089 ! neuron apoptosis GO:0051402 9 6 0,000 0,0283497 0,09661385 ! nucleoside salvage GO:0043174 9 6 0,000 0,0283497 0,0964772 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0283497 0,09634093 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0283497 0,09620505 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0283497 0,09606955 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,0283497 0,09593443 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0283497 0,09579969 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0283497 0,09566533 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0283497 0,09553134 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0283497 0,09539773 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0283497 0,09526449 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0283497 0,09513163 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0283497 0,09499913 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0283497 0,09486701 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0283497 0,09473525 ! establishment of spindle localization GO:0051293 12 6 0,000 0,0283497 0,09460385 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0283497 0,09447282 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0283497 0,09434216 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,0283497 0,09421185 ! neural nucleus development GO:0048857 14 6 0,000 0,0283497 0,0940819 ! response to UV-C GO:0010225 11 6 0,000 0,0283497 0,09395231 ! astrocyte development GO:0014002 15 6 0,000 0,0283497 0,09382308 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0283497 0,0936942 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0283497 0,09356568 ! interaction with symbiont GO:0051702 13 6 0,000 0,0283497 0,0934375 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0283497 0,09330968 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0283497 0,09318221 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0283497 0,09305509 ! response to copper ion GO:0046688 10 6 0,000 0,0283497 0,09292831 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0283497 0,09280187 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0283497 0,09267579 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0283497 0,09255004 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0283497 0,09242463 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0283497 0,09229956 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0283497 0,09217484 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0283497 0,09205044 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0283497 0,09192639 ! hair follicle maturation GO:0048820 7 6 0,000 0,0283497 0,09180266 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0283497 0,09167927 ! Schwann cell development GO:0014044 15 6 0,000 0,0283497 0,09155621 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0283497 0,09143348 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0283497 0,09131108 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,0283497 0,09118901 ! subpallium development GO:0021544 10 6 0,000 0,0283497 0,09106726 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0283497 0,09094584 ! histone ubiquitination GO:0016574 8 6 0,000 0,0283497 0,09082474 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0283497 0,09070396 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0283497 0,0905835 ! G2 phase GO:0051319 16 6 0,000 0,0283497 0,09046337 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0283497 0,09034355 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0283497 0,09022405 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0283497 0,09010486 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0283497 0,08998599 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0283497 0,08986743 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0283497 0,08974918 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0283497 0,08963125 ! receptor internalization GO:0031623 10 6 0,000 0,0283497 0,08951362 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,0283497 0,0893963 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0283497 0,08927929 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0283497 0,08916259 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0283497 0,08904619 ! protein deubiquitination GO:0016579 14 6 0,000 0,0283497 0,08893009 ! protein destabilization GO:0031648 9 6 0,000 0,0283497 0,08881429 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0283497 0,0886988 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0283497 0,08858361 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0283497 0,08846871 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0283497 0,08835412 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0283497 0,08823982 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0283497 0,08812581 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0283497 0,0880121 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0283497 0,08789868 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0283497 0,08778556 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0283497 0,08767272 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0283497 0,08756018 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0283497 0,08744792 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0283497 0,08733595 ! catecholamine transport GO:0051937 9 6 0,000 0,0283497 0,08722427 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0283497 0,08711287 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0283497 0,08700176 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0283497 0,08689093 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0283497 0,08678038 ! maternal placenta development GO:0001893 12 6 0,000 0,0283497 0,08667011 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0283497 0,08656012 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0283497 0,08645042 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0283497 0,08634098 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0283497 0,08623183 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0283497 0,08612295 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0283497 0,08601435 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,02857935 0,0866019 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,02857935 0,08649297 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,02857935 0,08638431 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,02857935 0,08627592 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,02954654 0,08908391 ! lipid modification GO:0030258 97 57 1,000 0,03052666 0,09192383 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,03052666 0,09180892 ! adult behavior GO:0030534 99 58 1,000 0,03151957 0,09467676 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,03151957 0,0945587 ! DNA catabolic process GO:0006308 86 59 1,000 0,03252513 0,09745386 ! establishment of organelle localization GO:0051656 109 59 1,000 0,03252513 0,09733265 ! tRNA transcription GO:0009304 14 7 0,000 0,03299643 0,09862038 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03299643 0,09849802 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03299643 0,09837597 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03299643 0,09825422 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03299643 0,09813277 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03299643 0,09801161 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03299643 0,09789076 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03299643 0,09777021 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03299643 0,09764995 ! prostate gland development GO:0030850 13 7 0,000 0,03299643 0,09752998 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03299643 0,09741032 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03299643 0,09729094 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03299643 0,09717186 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03299643 0,09705306 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03299643 0,09693456 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03299643 0,09681635 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03299643 0,09669843 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03299643 0,09658079 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03299643 0,09646343 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03299643 0,09634637 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03299643 0,09622958 ! glycolipid transport GO:0046836 10 7 0,000 0,03299643 0,09611308 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03299643 0,09599686 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03299643 0,09588093 ! neuron adhesion GO:0007158 12 7 0,000 0,03299643 0,09576527 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03299643 0,09564989 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03299643 0,09553479 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03299643 0,09541996 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03299643 0,09530541 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03299643 0,09519114 ! pericardium development GO:0060039 14 7 0,000 0,03299643 0,09507713 ! fibril organization GO:0043206 16 7 0,000 0,03299643 0,09496341 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03299643 0,09484995 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03299643 0,09473676 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03299643 0,09462385 ! lipoprotein transport GO:0042953 14 7 0,000 0,03299643 0,0945112 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03299643 0,09439882 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03299643 0,09428671 ! rhythmic behavior GO:0007622 15 7 0,000 0,03299643 0,09417486 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03299643 0,09406328 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03299643 0,09395196 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03299643 0,09384091 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03299643 0,09373011 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03299643 0,09361958 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03299643 0,09350931 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03299643 0,0933993 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03299643 0,09328955 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03299643 0,09318006 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03299643 0,09307082 GO:0045911|positive regulation of DNA recombination, ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03299643 0,09296183 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03299643 0,09285311 ! spinal cord patterning GO:0021511 13 7 0,000 0,03299643 0,09274463 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03299643 0,09263641 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03299643 0,09252845 ! adrenal gland development GO:0030325 17 7 0,000 0,03299643 0,09242073 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03299643 0,09231326 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03299643 0,09220605 ! ovulation GO:0030728 9 7 0,000 0,03299643 0,09209908 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03299643 0,09199236 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03299643 0,09188589 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03299643 0,09177966 ! microtubule nucleation GO:0007020 20 7 0,000 0,03299643 0,09167368 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03299643 0,09156794 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03299643 0,09146245 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03299643 0,0913572 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03299643 0,09125219 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03299643 0,09114742 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03299643 0,0910429 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03299643 0,09093861 ! galactose metabolic process GO:0006012 13 7 0,000 0,03299643 0,09083456 ! vesicle fusion GO:0006906 17 7 0,000 0,03299643 0,09073075 ! response to dietary excess GO:0002021 8 7 0,000 0,03299643 0,09062718 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03299643 0,09052384 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03299643 0,09042074 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03299643 0,09031787 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03299643 0,09021524 ! organ growth GO:0035265 15 7 0,000 0,03299643 0,09011283 ! purine salvage GO:0043101 10 7 0,000 0,03299643 0,09001067 ! nucleoside transport GO:0015858 8 7 0,000 0,03299643 0,08990873 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03299643 0,08980702 ! parturition GO:0007567 14 7 0,000 0,03299643 0,08970554 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03299643 0,0896043 ! rRNA modification GO:0000154 14 7 0,000 0,03299643 0,08950328 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03299643 0,08940249 ! spindle checkpoint GO:0031577 15 7 0,000 0,03299643 0,08930192 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03299643 0,08920158 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03299643 0,08910147 ! macrophage differentiation GO:0030225 11 7 0,000 0,03299643 0,08900158 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03299643 0,08890191 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03299643 0,08880247 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03299643 0,08870325 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03299643 0,08860425 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03299643 0,08850547 ! fibrinolysis GO:0042730 10 7 0,000 0,03299643 0,08840691 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03299643 0,08830857 ! eating behavior GO:0042755 7 7 0,000 0,03299643 0,08821045 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03299643 0,08811255 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03299643 0,08801486 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03299643 0,08791739 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03299643 0,08782014 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03299643 0,0877231 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03299643 0,08762628 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03299643 0,08752967 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03299643 0,08743327 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03299643 0,08733708 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03299643 0,08724111 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03299643 0,08714534 ! regulation of meiosis GO:0040020 12 7 0,000 0,03299643 0,08704979 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03299643 0,08695444 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03299643 0,08685931 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03299643 0,08676438 ! transcription termination GO:0006353 13 7 0,000 0,03299643 0,08666966 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03299643 0,08657514 ! anaphase GO:0051322 17 7 0,000 0,03299643 0,08648084 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03299643 0,08638673 ! axonal fasciculation GO:0007413 18 7 0,000 0,03299643 0,08629283 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03299643 0,08619914 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03299643 0,08610565 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03299643 0,08601236 ! diuresis GO:0030146 12 7 0,000 0,03299643 0,08591927 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03299643 0,08582639 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03299643 0,0857337 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03299643 0,08564122 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03299643 0,08554893 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03299643 0,08545684 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03299643 0,08536495 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03299643 0,08527326 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03299643 0,08518177 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03299643 0,08509047 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03299643 0,08499937 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03299643 0,08490846 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03299643 0,08481774 ! lymph node development GO:0048535 10 7 0,000 0,03299643 0,08472722 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03299643 0,08463689 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03299643 0,08454676 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03299643 0,08445682 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03299643 0,08436706 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03299643 0,0842775 ! adult feeding behavior GO:0008343 9 7 0,000 0,03299643 0,08418813 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03299643 0,08409895 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03299643 0,08400995 ! muscle adaptation GO:0043500 14 7 0,000 0,03299643 0,08392115 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03299643 0,08383253 ! retina homeostasis GO:0001895 12 7 0,000 0,03299643 0,0837441 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03299643 0,08365586 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03299643 0,0835678 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03299643 0,08347992 ! protein prenylation GO:0018342 18 7 0,000 0,03299643 0,08339223 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03299643 0,08330473 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03299643 0,08321741 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03299643 0,08313027 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,03354319 0,08441936 ! regulation of heart contraction GO:0008016 110 60 1,000 0,03354319 0,08433115 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,03354319 0,08424312 ! viral reproductive process GO:0022415 126 62 1,000 0,03561627 0,08935635 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03762109 0,09428785 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03762109 0,09418974 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03762109 0,09409183 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03762109 0,09399412 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03762109 0,09389662 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03762109 0,09379932 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03762109 0,09370221 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03762109 0,09360531 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03762109 0,09350861 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03762109 0,09341211 ! meiotic prophase I GO:0007128 13 8 0,000 0,03762109 0,09331581 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03762109 0,09321971 ! oligopeptide transport GO:0006857 15 8 0,000 0,03762109 0,09312381 ! UTP metabolic process GO:0046051 8 8 0,000 0,03762109 0,0930281 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03762109 0,09293259 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03762109 0,09283727 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03762109 0,09274215 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03762109 0,09264723 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03762109 0,09255249 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03762109 0,09245796 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03762109 0,09236361 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03762109 0,09226946 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03762109 0,0921755 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03762109 0,09208173 ! reflex GO:0060004 16 8 0,000 0,03762109 0,09198815 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03762109 0,09189476 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03762109 0,09180156 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03762109 0,09170855 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03762109 0,09161573 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03762109 0,09152309 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03762109 0,09143065 ! pigment granule organization GO:0048753 16 8 0,000 0,03762109 0,09133838 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03762109 0,09124631 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03762109 0,09115442 ! histidine metabolic process GO:0006547 16 8 0,000 0,03762109 0,09106272 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03762109 0,0909712 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03762109 0,09087986 ! glycine catabolic process GO:0006546 13 8 0,000 0,03762109 0,09078871 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03762109 0,09069773 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03762109 0,09060695 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03762109 0,09051634 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03762109 0,09042591 ! melanin metabolic process GO:0006582 15 8 0,000 0,03762109 0,09033567 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03762109 0,0902456 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03762109 0,09015572 ! macrophage activation GO:0042116 12 8 0,000 0,03762109 0,09006601 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03762109 0,08997648 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03762109 0,08988713 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03762109 0,08979796 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03762109 0,08970896 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03762109 0,08962014 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03762109 0,08953149 ! osteoblast development GO:0002076 16 8 0,000 0,03762109 0,08944302 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03762109 0,08935473 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03762109 0,08926661 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03762109 0,08917866 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03762109 0,08909088 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03762109 0,08900328 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03762109 0,08891585 ! response to UV-B GO:0010224 16 8 0,000 0,03762109 0,0888286 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03762109 0,08874151 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03762109 0,08865459 ! intermediate filament organization GO:0045109 12 8 0,000 0,03762109 0,08856785 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03762109 0,08848127 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03762109 0,08839486 ! cellular extravasation GO:0045123 12 8 0,000 0,03762109 0,08830862 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03762109 0,08822255 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03762109 0,08813665 ! response to antibiotic GO:0046677 11 8 0,000 0,03762109 0,08805091 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03762109 0,08796534 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03762109 0,08787994 ! DNA topological change GO:0006265 12 8 0,000 0,03762109 0,0877947 ! response to tropane GO:0014073 15 8 0,000 0,03762109 0,08770963 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03762109 0,08762472 ! melanosome transport GO:0032402 13 8 0,000 0,03762109 0,08753998 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03762109 0,0874554 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03762109 0,08737098 ! mast cell activation GO:0045576 14 8 0,000 0,03762109 0,08728673 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03762109 0,08720264 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03762109 0,08711871 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03762109 0,08703494 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03762109 0,08695133 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03762109 0,08686789 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03762109 0,0867846 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03762109 0,08670147 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03762109 0,08661851 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03762109 0,0865357 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03762109 0,08645305 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03762109 0,08637055 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03762109 0,08628822 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03762109 0,08620604 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03762109 0,08612401 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03762109 0,08604215 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03762109 0,08596044 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03762109 0,08587888 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03762109 0,08579748 ! hormone catabolic process GO:0042447 17 8 0,000 0,03762109 0,08571623 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03762109 0,08563514 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03762109 0,0855542 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03762109 0,08547341 ! ATP catabolic process GO:0006200 11 8 0,000 0,03762109 0,08539277 ! blastocyst growth GO:0001832 19 8 0,000 0,03762109 0,08531229 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03762109 0,08523196 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03762109 0,08515178 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03762109 0,08507175 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03762109 0,08499187 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03762109 0,08491214 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03762109 0,08483256 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03762109 0,08475313 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03762109 0,08467384 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03762109 0,08459471 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03762109 0,08451572 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03762109 0,08443688 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03762109 0,08435819 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03762109 0,08427965 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03762109 0,08420125 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03762109 0,08412299 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,03773769 0,08430537 GO:0048609|reproductive process in a multicellular organism, ! myeloid cell differentiation GO:0030099 111 65 1,000 0,03881619 0,08663427 ! actin filament organization GO:0007015 148 66 1,000 0,03990636 0,08898489 ! adaptive immune response GO:0002250 119 67 1,000 0,04100807 0,09135687 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,04212119 0,09374985 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 1,000 0,04212119 0,0936632 ! regulation of lipase activity GO:0060191 130 68 1,000 0,04212119 0,09357672 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,04212119 0,09349039 ! axon extension GO:0048675 15 9 0,000 0,04222378 0,09363173 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04222378 0,09354551 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04222378 0,09345945 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04222378 0,09337355 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04222378 0,09328781 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04222378 0,09320222 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04222378 0,0931168 ! phosphate transport GO:0006817 19 9 0,000 0,04222378 0,09303152 ! reproductive behavior GO:0019098 19 9 0,000 0,04222378 0,09294641 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04222378 0,09286145 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04222378 0,09277664 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04222378 0,09269199 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04222378 0,0926075 ! GTP metabolic process GO:0046039 9 9 0,000 0,04222378 0,09252316 ! RNA methylation GO:0001510 15 9 0,000 0,04222378 0,09243897 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04222378 0,09235493 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04222378 0,09227105 ! artery development GO:0060840 24 9 0,000 0,04222378 0,09218732 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04222378 0,09210374 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04222378 0,09202031 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04222378 0,09193704 ! chemosensory behavior GO:0007635 20 9 0,000 0,04222378 0,09185391 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04222378 0,09177093 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04222378 0,09168811 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04222378 0,09160543 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04222378 0,09152291 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04222378 0,09144053 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04222378 0,0913583 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04222378 0,09127621 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04222378 0,09119428 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04222378 0,09111249 ! protein targeting to ER GO:0045047 22 9 0,000 0,04222378 0,09103085 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04222378 0,09094935 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04222378 0,090868 ! T cell selection GO:0045058 23 9 0,000 0,04222378 0,0907868 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04222378 0,09070574 ! endosome organization GO:0007032 17 9 0,000 0,04222378 0,09062482 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04222378 0,09054405 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04222378 0,09046342 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04222378 0,09038294 ! mannose metabolic process GO:0006013 13 9 0,000 0,04222378 0,0903026 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04222378 0,0902224 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04222378 0,09014235 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04222378 0,09006243 ! receptor clustering GO:0043113 18 9 0,000 0,04222378 0,08998266 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04222378 0,08990303 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04222378 0,08982354 ! ruffle organization GO:0031529 15 9 0,000 0,04222378 0,08974419 ! retinol metabolic process GO:0042572 18 9 0,000 0,04222378 0,08966498 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04222378 0,08958591 ! behavioral fear response GO:0001662 22 9 0,000 0,04222378 0,08950698 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04222378 0,08942819 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04222378 0,08934954 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04222378 0,08927102 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,04222378 0,08919265 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04222378 0,08911441 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04222378 0,08903631 ! segment specification GO:0007379 13 9 0,000 0,04222378 0,08895834 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04222378 0,08888051 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04222378 0,08880282 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04222378 0,08872526 ! response to amine stimulus GO:0014075 13 9 0,000 0,04222378 0,08864784 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04222378 0,08857055 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04222378 0,0884934 ! erythrocyte development GO:0048821 15 9 0,000 0,04222378 0,08841638 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04222378 0,0883395 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04222378 0,08826275 ! renal water homeostasis GO:0003091 14 9 0,000 0,04222378 0,08818613 ! postreplication repair GO:0006301 22 9 0,000 0,04222378 0,08810965 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04222378 0,0880333 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04222378 0,08795708 ! icosanoid secretion GO:0032309 15 9 0,000 0,04222378 0,08788099 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04222378 0,08780503 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04222378 0,08772921 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04222378 0,08765352 ! regulation of cell division GO:0051302 15 9 0,000 0,04222378 0,08757795 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04222378 0,08750252 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04222378 0,08742722 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04222378 0,08735204 ! sterol catabolic process GO:0016127 11 9 0,000 0,04222378 0,087277 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04222378 0,08720208 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04222378 0,08712729 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04222378 0,08705263 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04222378 0,0869781 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04222378 0,0869037 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04222378 0,08682942 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04222378 0,08675527 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04222378 0,08668125 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04222378 0,08660735 ! purine base metabolic process GO:0006144 21 9 0,000 0,04222378 0,08653358 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04222378 0,08645994 ! pigment granule transport GO:0051904 17 9 0,000 0,04222378 0,08638642 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04222378 0,08631302 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04222378 0,08623975 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04222378 0,0861666 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04222378 0,08609358 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04222378 0,08602068 ! mitochondrion localization GO:0051646 15 9 0,000 0,04222378 0,08594791 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,04324559 0,08795341 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,04668512 0,09486857 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,04668512 0,09478851 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,04668512 0,09470859 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04680462 0,09487103 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04680462 0,09479117 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04680462 0,09471145 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04680462 0,09463186 ! synapsis GO:0007129 13 10 0,000 0,04680462 0,0945524 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04680462 0,09447308 ! N-glycan processing GO:0006491 20 10 0,000 0,04680462 0,09439389 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04680462 0,09431484 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04680462 0,09423591 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04680462 0,09415712 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04680462 0,09407846 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04680462 0,09399993 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,04680462 0,09392153 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04680462 0,09384326 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04680462 0,09376512 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04680462 0,09368712 ! androgen metabolic process GO:0008209 17 10 0,000 0,04680462 0,09360924 ! phospholipid efflux GO:0033700 16 10 0,000 0,04680462 0,09353149 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04680462 0,09345387 ! pathogenesis GO:0009405 13 10 0,000 0,04680462 0,09337638 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04680462 0,09329902 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04680462 0,09322178 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04680462 0,09314468 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04680462 0,0930677 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04680462 0,09299085 ! endoderm development GO:0007492 16 10 0,000 0,04680462 0,09291412 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04680462 0,09283752 ! arginine catabolic process GO:0006527 13 10 0,000 0,04680462 0,09276105 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04680462 0,0926847 ! proline metabolic process GO:0006560 13 10 0,000 0,04680462 0,09260848 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04680462 0,09253239 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04680462 0,09245641 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04680462 0,09238057 ! V(D)J recombination GO:0033151 28 10 0,000 0,04680462 0,09230485 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04680462 0,09222925 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04680462 0,09215378 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04680462 0,09207842 ! B cell proliferation GO:0042100 18 10 0,000 0,04680462 0,0920032 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04680462 0,09192809 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04680462 0,09185311 ! multicellular organism growth GO:0035264 18 10 0,000 0,04680462 0,09177825 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04680462 0,09170351 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04680462 0,0916289 ! epithelial cell development GO:0002064 20 10 0,000 0,04680462 0,0915544 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04680462 0,09148003 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04680462 0,09140577 ! macroautophagy GO:0016236 17 10 0,000 0,04680462 0,09133164 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04680462 0,09125763 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04680462 0,09118374 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04680462 0,09110996 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04680462 0,09103631 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04680462 0,09096277 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04680462 0,09088936 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04680462 0,09081606 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04680462 0,09074288 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04680462 0,09066982 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04680462 0,09059687 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04680462 0,09052405 ! response to dsRNA GO:0043331 20 10 0,000 0,04680462 0,09045134 ! DNA ligation GO:0006266 19 10 0,000 0,04680462 0,09037874 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04680462 0,09030627 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04680462 0,0902339 ! melanosome localization GO:0032400 16 10 0,000 0,04680462 0,09016166 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04680462 0,09008953 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04680462 0,09001752 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04680462 0,08994562 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04680462 0,08987383 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04680462 0,08980216 ! mRNA cleavage GO:0006379 17 10 0,000 0,04680462 0,08973061 ! protein sumoylation GO:0016925 15 10 0,000 0,04680462 0,08965917 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04680462 0,08958784 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04680462 0,08951662 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04680462 0,08944552 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04680462 0,08937453 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04680462 0,08930366 ! salivary gland development GO:0007431 27 10 0,000 0,04680462 0,08923289 ! prophase GO:0051324 15 10 0,000 0,04680462 0,08916224 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04680462 0,0890917 ! apical protein localization GO:0045176 15 10 0,000 0,04680462 0,08902128 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04680462 0,08895096 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04680462 0,08888075 ! midbrain development GO:0030901 13 10 0,000 0,04680462 0,08881066 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04680462 0,08874067 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04680462 0,0886708 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04680462 0,08860103 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04680462 0,08853138 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04680462 0,08846183 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04680462 0,0883924 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04680462 0,08832307 ! detection of calcium ion GO:0005513 23 10 0,000 0,04680462 0,08825385 ! oocyte development GO:0048599 17 10 0,000 0,04680462 0,08818474 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04680462 0,08811574 ! blastocyst formation GO:0001825 17 10 0,000 0,04680462 0,08804684 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04680462 0,08797806 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04680462 0,08790938 ! activation of innate immune response GO:0002218 12 10 0,000 0,04680462 0,08784081 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04680462 0,08777234 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04680462 0,08770398 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04680462 0,08763573 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04680462 0,08756758 ! learning or memory GO:0007611 147 73 1,000 0,04785331 0,08946003 ! regulation of blood pressure GO:0008217 125 73 1,000 0,04785331 0,08939057 ! neurotransmitter transport GO:0006836 123 74 1,000 0,04903212 0,09152156 ! exocytosis GO:0006887 133 74 1,000 0,04903212 0,09145061 ! organelle localization GO:0051640 136 74 1,000 0,04903212 0,09137977 ! meiosis GO:0007126 121 74 1,000 0,04903212 0,09130905 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 1,000 0,05022144 0,0934515 ! rhythmic process GO:0048511 128 75 1,000 0,05022144 0,09337928 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,05022144 0,09330717 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,0513637 0,09535575 ! respiratory burst GO:0045730 17 11 0,000 0,0513637 0,09528223 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0513637 0,09520882 ! neuron fate specification GO:0048665 17 11 0,000 0,0513637 0,09513553 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0513637 0,09506235 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0513637 0,09498928 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0513637 0,09491632 ! thyroid gland development GO:0030878 26 11 0,000 0,0513637 0,09484348 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0513637 0,09477075 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0513637 0,09469812 ! response to pain GO:0048265 24 11 0,000 0,0513637 0,09462561 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0513637 0,09455322 ! T cell proliferation GO:0042098 26 11 0,000 0,0513637 0,09448093 ! bone resorption GO:0045453 16 11 0,000 0,0513637 0,09440875 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0513637 0,09433668 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0513637 0,09426472 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0513637 0,09419288 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0513637 0,09412114 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0513637 0,09404951 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0513637 0,09397799 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0513637 0,09390658 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0513637 0,09383527 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,0513637 0,09376408 ! UV protection GO:0009650 19 11 0,000 0,0513637 0,09369299 ! adult heart development GO:0007512 14 11 0,000 0,0513637 0,09362201 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0513637 0,09355114 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0513637 0,09348037 ! temperature homeostasis GO:0001659 17 11 0,000 0,0513637 0,09340972 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0513637 0,09333916 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0513637 0,09326872 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0513637 0,09319838 ! regulation of organ growth GO:0046620 13 11 0,000 0,0513637 0,09312815 ! pigment granule localization GO:0051875 20 11 0,000 0,0513637 0,09305802 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0513637 0,092988 ! vasoconstriction GO:0042310 18 11 0,000 0,0513637 0,09291808 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0513637 0,09284827 ! embryonic axis specification GO:0000578 18 11 0,000 0,0513637 0,09277857 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0513637 0,09270897 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0513637 0,09263947 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0513637 0,09257008 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0513637 0,09250079 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0513637 0,0924316 GO:0006305|DNA alkylation, ! zymogen activation GO:0031638 15 11 0,000 0,0513637 0,09236252 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0513637 0,09229354 ! neuroblast proliferation GO:0007405 24 11 0,000 0,0513637 0,09222467 ! nucleosome positioning GO:0016584 15 11 0,000 0,0513637 0,09215589 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0513637 0,09208722 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0513637 0,09201865 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0513637 0,09195019 ! acid secretion GO:0046717 18 11 0,000 0,0513637 0,09188182 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0513637 0,09181356 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0513637 0,0917454 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0513637 0,09167734 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0513637 0,09160938 ! oocyte differentiation GO:0009994 18 11 0,000 0,0513637 0,09154152 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0513637 0,09147376 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,0513637 0,0914061 ! cholesterol efflux GO:0033344 19 11 0,000 0,0513637 0,09133855 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0513637 0,09127109 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0513637 0,09120373 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0513637 0,09113647 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,0513637 0,09106931 ! embryonic gut development GO:0048566 15 11 0,000 0,0513637 0,09100225 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0513637 0,09093529 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0513637 0,09086842 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0513637 0,09080166 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0513637 0,09073499 ! defense response to fungus GO:0050832 13 11 0,000 0,0513637 0,09066842 ! developmental induction GO:0031128 19 11 0,000 0,0513637 0,09060194 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,0513637 0,09053557 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0513637 0,09046929 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0513637 0,09040311 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0513637 0,09033703 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0513637 0,09027104 ! nucleus localization GO:0051647 19 11 0,000 0,0513637 0,09020515 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0513637 0,09013935 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,05263107 0,09229618 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,05263107 0,09222896 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,05385114 0,09429828 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,05385114 0,0942297 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,05508121 0,09631205 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,05508121 0,09624211 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05590112 0,09760384 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05590112 0,09753306 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05590112 0,09746238 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05590112 0,09739181 ! cartilage condensation GO:0001502 20 12 0,000 0,05590112 0,09732134 ! mating GO:0007618 17 12 0,000 0,05590112 0,09725097 ! protein complex disassembly GO:0043241 27 12 0,000 0,05590112 0,0971807 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05590112 0,09711053 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,05590112 0,09704047 ! hippocampus development GO:0021766 26 12 0,000 0,05590112 0,0969705 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,05590112 0,09690064 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05590112 0,09683088 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05590112 0,09676122 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05590112 0,09669165 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05590112 0,09662219 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05590112 0,09655283 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05590112 0,09648357 ! drug transport GO:0015893 16 12 0,000 0,05590112 0,0964144 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05590112 0,09634534 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05590112 0,09627637 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05590112 0,0962075 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05590112 0,09613874 ! focal adhesion formation GO:0048041 35 12 0,000 0,05590112 0,09607006 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05590112 0,09600149 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05590112 0,09593302 ! forebrain cell migration GO:0021885 21 12 0,000 0,05590112 0,09586464 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05590112 0,09579636 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05590112 0,09572818 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05590112 0,09566009 ! entry into host cell GO:0030260 32 12 0,000 0,05590112 0,0955921 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,05590112 0,09552421 ! monoamine transport GO:0015844 18 12 0,000 0,05590112 0,09545642 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05590112 0,09538872 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05590112 0,09532111 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05590112 0,09525361 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05590112 0,09518619 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05590112 0,09511888 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05590112 0,09505165 ! protein homotetramerization GO:0051289 21 12 0,000 0,05590112 0,09498453 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05590112 0,09491749 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05590112 0,09485056 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05590112 0,09478371 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05590112 0,09471697 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05590112 0,09465031 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05590112 0,09458375 ! cranial nerve development GO:0021545 20 12 0,000 0,05590112 0,09451728 ! fucose catabolic process GO:0019317 22 12 0,000 0,05590112 0,09445091 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05590112 0,09438462 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05590112 0,09431844 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05590112 0,09425234 ! gland morphogenesis GO:0022612 29 12 0,000 0,05590112 0,09418634 ! T cell homeostasis GO:0043029 25 12 0,000 0,05590112 0,09412043 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05590112 0,09405461 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05590112 0,09398888 ! spleen development GO:0048536 22 12 0,000 0,05590112 0,09392325 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05590112 0,0938577 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,05590112 0,09379225 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05590112 0,09372689 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05590112 0,09366162 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05590112 0,09359644 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05590112 0,09353136 ! response to cold GO:0009409 17 12 0,000 0,05590112 0,09346636 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05590112 0,09340145 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05590112 0,09333663 ! response to metal ion GO:0010038 140 80 1,000 0,05632116 0,09397275 ! protein import into nucleus GO:0006606 158 80 1,000 0,05632116 0,09390763 ! nuclear import GO:0051170 161 81 1,000 0,05757087 0,09592487 ! response to drug GO:0042493 143 82 1,000 0,05883022 0,09795536 ! response to nutrient GO:0007584 125 82 1,000 0,05883022 0,09788762 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06041699 0,10045838 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06041699 0,100389 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06041699 0,10031972 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06041699 0,10025053 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06041699 0,10018144 ! lipid localization GO:0010876 28 13 0,000 0,06041699 0,10011245 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06041699 0,10004355 ! organelle fusion GO:0048284 32 13 0,000 0,06041699 0,09997474 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06041699 0,09990603 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06041699 0,09983741 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06041699 0,09976889 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06041699 0,09970046 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06041699 0,09963213 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06041699 0,09956388 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06041699 0,09949574 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06041699 0,09942768 ! methionine metabolic process GO:0006555 27 13 0,000 0,06041699 0,09935972 ! plasma membrane organization GO:0007009 24 13 0,000 0,06041699 0,09929185 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06041699 0,09922408 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06041699 0,09915639 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06041699 0,0990888 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06041699 0,0990213 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06041699 0,09895389 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06041699 0,09888658 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06041699 0,09881936 ! exocrine system development GO:0035272 32 13 0,000 0,06041699 0,09875222 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06041699 0,09868518 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06041699 0,09861823 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06041699 0,09855137 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06041699 0,0984846 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06041699 0,09841792 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06041699 0,09835133 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06041699 0,09828484 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06041699 0,09821843 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06041699 0,09815211 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06041699 0,09808588 ! ribosome assembly GO:0042255 17 13 0,000 0,06041699 0,09801974 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06041699 0,09795369 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06041699 0,09788772 ! chromatin silencing GO:0006342 26 13 0,000 0,06041699 0,09782185 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06041699 0,09775607 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06041699 0,09769037 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06041699 0,09762476 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06041699 0,09755924 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06041699 0,09749381 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06041699 0,09742847 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06041699 0,09736321 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06041699 0,09729804 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06041699 0,09723296 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06041699 0,09716796 ! insulin secretion GO:0030073 23 13 0,000 0,06041699 0,09710305 ! actin filament polymerization GO:0030041 24 13 0,000 0,06041699 0,09703823 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06041699 0,0969735 ! acrosome reaction GO:0007340 18 13 0,000 0,06041699 0,09690885 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,06137736 0,09838369 ! response to unfolded protein GO:0006986 131 85 1,000 0,06266491 0,10038067 ! nucleosome assembly GO:0006334 122 85 1,000 0,06266491 0,10031389 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,06266491 0,10024719 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,06266491 0,10018058 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 1,000 0,06396163 0,10218571 ! response to inorganic substance GO:0010035 153 86 1,000 0,06396163 0,10211791 ! chromatin assembly GO:0031497 124 86 1,000 0,06396163 0,10205019 ! rRNA transcription GO:0009303 25 14 0,000 0,06491141 0,10349691 ! lactation GO:0007595 26 14 0,000 0,06491141 0,10342837 ! reproductive cellular process GO:0048610 20 14 0,000 0,06491141 0,10335992 ! tRNA modification GO:0006400 20 14 0,000 0,06491141 0,10329156 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06491141 0,10322329 ! water transport GO:0006833 21 14 0,000 0,06491141 0,10315511 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06491141 0,10308702 ! non-recombinational repair GO:0000726 25 14 0,000 0,06491141 0,10301902 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06491141 0,10295111 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06491141 0,10288329 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06491141 0,10281556 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,06491141 0,10274792 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06491141 0,10268037 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06491141 0,1026129 ! palate development GO:0060021 31 14 0,000 0,06491141 0,10254553 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,06491141 0,10247824 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06491141 0,10241104 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06491141 0,10234393 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06491141 0,10227691 ! arginine metabolic process GO:0006525 17 14 0,000 0,06491141 0,10220997 ! organic alcohol transport GO:0015850 29 14 0,000 0,06491141 0,10214313 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,06491141 0,10207637 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,06491141 0,10200969 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06491141 0,10194311 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06491141 0,10187661 ! L-amino acid transport GO:0015807 30 14 0,000 0,06491141 0,1018102 ! bone mineralization GO:0030282 17 14 0,000 0,06491141 0,10174387 ! stem cell development GO:0048864 43 14 0,000 0,06491141 0,10167763 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06491141 0,10161148 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,06491141 0,10154541 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06491141 0,10147943 ! cerebellum development GO:0021549 21 14 0,000 0,06491141 0,10141353 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06491141 0,10134772 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06491141 0,101282 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06491141 0,10121636 ! cofactor transport GO:0051181 26 14 0,000 0,06491141 0,1011508 ! NADP metabolic process GO:0006739 24 14 0,000 0,06491141 0,10108533 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06491141 0,10101995 ! intestinal absorption GO:0050892 25 14 0,000 0,06491141 0,10095465 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06491141 0,10088943 ! oxygen transport GO:0015671 21 14 0,000 0,06491141 0,1008243 ! male genitalia development GO:0030539 24 14 0,000 0,06491141 0,10075925 ! regulation of axon extension GO:0030516 37 14 0,000 0,06491141 0,10069429 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06491141 0,10062941 ! protein localization in nucleus GO:0034504 176 87 1,000 0,06526741 0,10111615 ! regulation of neurological system process GO:0031644 148 88 1,000 0,06658212 0,1030866 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,06790565 0,10506817 ! ossification GO:0001503 188 90 1,000 0,0692379 0,10706065 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,0692379 0,10699189 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06938447 0,10714958 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06938447 0,10708085 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,06938447 0,10701221 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06938447 0,10694365 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06938447 0,10687519 ! copper ion transport GO:0006825 20 15 0,000 0,06938447 0,10680681 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06938447 0,10673852 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06938447 0,10667031 ! sulfate transport GO:0008272 23 15 0,000 0,06938447 0,1066022 ! response to cAMP GO:0051591 22 15 0,000 0,06938447 0,10653417 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06938447 0,10646623 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06938447 0,10639837 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06938447 0,1063306 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06938447 0,10626292 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06938447 0,10619532 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06938447 0,10612781 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06938447 0,10606038 ! pituitary gland development GO:0021983 29 15 0,000 0,06938447 0,10599304 ! vesicle coating GO:0006901 33 15 0,000 0,06938447 0,10592579 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06938447 0,10585862 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06938447 0,10579153 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06938447 0,10572454 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06938447 0,10565762 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06938447 0,10559079 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06938447 0,10552405 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06938447 0,10545739 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06938447 0,10539081 ! histone deacetylation GO:0016575 20 15 0,000 0,06938447 0,10532432 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06938447 0,10525791 ! tissue regeneration GO:0042246 26 15 0,000 0,06938447 0,10519158 ! water homeostasis GO:0030104 27 15 0,000 0,06938447 0,10512534 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06938447 0,10505918 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06938447 0,10499311 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06938447 0,10492712 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06938447 0,10486121 ! cell killing GO:0001906 29 15 0,000 0,06938447 0,10479538 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,06938447 0,10472964 ! detection of bacterium GO:0016045 18 15 0,000 0,06938447 0,10466398 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06938447 0,1045984 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06938447 0,1045329 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06938447 0,10446749 ! peptide hormone processing GO:0016486 23 15 0,000 0,06938447 0,10440215 ! bone development GO:0060348 189 91 1,000 0,07057874 0,10613278 ! response to protein stimulus GO:0051789 149 91 1,000 0,07057874 0,10606649 ! regulation of defense response GO:0031347 149 92 1,000 0,07192807 0,1080268 ! nucleosome organization GO:0034728 138 92 1,000 0,07192807 0,10795941 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,07328577 0,10992866 GO:0010498|proteasomal protein catabolic process, ! regulation of membrane potential GO:0042391 164 93 1,000 0,07328577 0,10986017 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,07383629 0,11061651 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07383629 0,11054768 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07383629 0,11047893 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,07383629 0,11041027 ! bone remodeling GO:0046849 27 16 0,000 0,07383629 0,11034169 ! filopodium assembly GO:0046847 32 16 0,000 0,07383629 0,11027319 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,07383629 0,11020479 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07383629 0,11013646 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,07383629 0,11006823 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,07383629 0,11000007 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,07383629 0,109932 ! startle response GO:0001964 28 16 0,000 0,07383629 0,10986402 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,07383629 0,10979612 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,07383629 0,1097283 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,07383629 0,10966057 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07383629 0,10959292 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,07383629 0,10952535 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07383629 0,10945787 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07383629 0,10939047 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,07383629 0,10932315 ! response to osmotic stress GO:0006970 25 16 0,000 0,07383629 0,10925591 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,07383629 0,10918876 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,07383629 0,10912169 ! fructose metabolic process GO:0006000 25 16 0,000 0,07383629 0,10905471 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07383629 0,1089878 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07383629 0,10892098 ! intermediate filament-based process GO:0045103 32 16 0,000 0,07383629 0,10885424 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,07383629 0,10878758 ! negative regulation of immune response GO:0050777 35 16 0,000 0,07383629 0,108721 ! axon cargo transport GO:0008088 43 16 0,000 0,07383629 0,10865451 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07383629 0,10858809 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,07383629 0,10852176 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,07383629 0,1084555 ! DNA replication initiation GO:0006270 27 16 0,000 0,07383629 0,10838933 ! neuron recognition GO:0008038 35 16 0,000 0,07383629 0,10832324 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,07383629 0,10825723 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07383629 0,1081913 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,07383629 0,10812545 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07383629 0,10805968 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,07383629 0,10799399 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07383629 0,10792838 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07383629 0,10786285 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07383629 0,1077974 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,07383629 0,10773203 ! defense response to virus GO:0051607 37 16 0,000 0,07383629 0,10766674 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,07465174 0,10878988 ! transcription initiation GO:0006352 153 94 1,000 0,07465174 0,10872403 ! regulation of T cell activation GO:0050863 158 94 1,000 0,07465174 0,10865826 ! leukocyte differentiation GO:0002521 202 96 1,000 0,07740805 0,11260204 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07826696 0,11378266 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,07826696 0,11371395 ! metencephalon development GO:0022037 30 17 0,000 0,07826696 0,11364533 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,07826696 0,11357678 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,07826696 0,11350832 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07826696 0,11343994 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07826696 0,11337165 ! signal complex assembly GO:0007172 41 17 0,000 0,07826696 0,11330343 ! endothelial cell migration GO:0043542 28 17 0,000 0,07826696 0,1132353 ! inositol metabolic process GO:0006020 28 17 0,000 0,07826696 0,11316725 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07826696 0,11309928 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07826696 0,1130314 ! glial cell development GO:0021782 27 17 0,000 0,07826696 0,11296359 ! limbic system development GO:0021761 36 17 0,000 0,07826696 0,11289587 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07826696 0,11282822 ! adult walking behavior GO:0007628 33 17 0,000 0,07826696 0,11276066 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07826696 0,11269318 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,07826696 0,11262578 ! myoblast differentiation GO:0045445 45 17 0,000 0,07826696 0,11255846 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07826696 0,11249122 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,07826696 0,11242406 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07826696 0,11235698 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07826696 0,11228999 ! glycine metabolic process GO:0006544 28 17 0,000 0,07826696 0,11222307 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07826696 0,11215623 ! NAD metabolic process GO:0019674 29 17 0,000 0,07826696 0,11208947 ! membrane budding GO:0006900 37 17 0,000 0,07826696 0,11202279 ! DNA integration GO:0015074 29 17 0,000 0,07826696 0,11195619 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,07826696 0,11188967 ! regulation of protein binding GO:0043393 33 17 0,000 0,07826696 0,11182322 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07826696 0,11175686 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07826696 0,11169057 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07826696 0,11162437 ! genitalia development GO:0048806 30 17 0,000 0,07826696 0,11155824 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07826696 0,11149219 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,07826696 0,11142622 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,07826696 0,11136032 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07826696 0,11129451 ! steroid catabolic process GO:0006706 31 17 0,000 0,07826696 0,11122877 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,07826696 0,11116311 ! gas transport GO:0015669 25 17 0,000 0,07826696 0,11109753 ! organic cation transport GO:0015695 31 17 0,000 0,07826696 0,11103202 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07826696 0,11096659 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07826696 0,11090124 ! microspike assembly GO:0030035 36 17 0,000 0,07826696 0,11083597 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07826696 0,11077077 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,07826696 0,11070565 ! response to virus GO:0009615 160 98 1,000 0,08019613 0,11336774 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,08160182 0,11528713 GO:0060538|skeletal muscle organ development, ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08267658 0,116737 ! neuron maturation GO:0042551 42 18 0,000 0,08267658 0,11666853 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,08267658 0,11660015 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08267658 0,11653184 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08267658 0,11646361 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,08267658 0,11639547 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08267658 0,1163274 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08267658 0,11625941 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08267658 0,1161915 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08267658 0,11612367 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08267658 0,11605592 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,08267658 0,11598825 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,08267658 0,11592066 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08267658 0,11585315 ! response to retinoic acid GO:0032526 26 18 0,000 0,08267658 0,11578571 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,08267658 0,11571835 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,08267658 0,11565108 ! response to fungus GO:0009620 21 18 0,000 0,08267658 0,11558388 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,08267658 0,11551675 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,08267658 0,11544971 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08267658 0,11538274 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08267658 0,11531586 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08267658 0,11524905 ! vitamin transport GO:0051180 27 18 0,000 0,08267658 0,11518231 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,08267658 0,11511566 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08267658 0,11504908 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08267658 0,11498257 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08267658 0,11491615 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08267658 0,1148498 ! nerve development GO:0021675 28 18 0,000 0,08267658 0,11478353 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08267658 0,11471733 ! protein secretion GO:0009306 39 19 0,000 0,08706525 0,12073717 ! positive regulation of translation GO:0045727 30 19 0,000 0,08706525 0,12066762 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,08706525 0,12059815 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,08706525 0,12052876 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08706525 0,12045945 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,08706525 0,12039023 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,08706525 0,12032108 ! bile acid metabolic process GO:0008206 29 19 0,000 0,08706525 0,120252 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08706525 0,12018301 ! cerebral cortex development GO:0021987 36 19 0,000 0,08706525 0,1201141 ! pigmentation during development GO:0048066 41 19 0,000 0,08706525 0,12004527 ! response to vitamin A GO:0033189 27 19 0,000 0,08706525 0,11997651 ! heme metabolic process GO:0042168 36 19 0,000 0,08706525 0,11990784 ! neuromuscular junction development GO:0007528 34 19 0,000 0,08706525 0,11983924 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,08706525 0,11977072 ! plasma membrane fusion GO:0045026 28 19 0,000 0,08706525 0,11970228 ! peptide cross-linking GO:0018149 37 19 0,000 0,08706525 0,11963392 ! protein export from nucleus GO:0006611 36 19 0,000 0,08706525 0,11956563 ! heart process GO:0003015 30 19 0,000 0,08706525 0,11949743 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08706525 0,1194293 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08706525 0,11936125 ! visual learning GO:0008542 36 19 0,000 0,08706525 0,11929328 ! cellular pigmentation GO:0033059 36 19 0,000 0,08706525 0,11922538 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,08706525 0,11915756 ! cell-cell junction organization GO:0045216 35 19 0,000 0,08706525 0,11908982 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,08706525 0,11902215 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08706525 0,11895457 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,08706525 0,11888706 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,08706525 0,11881962 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08706525 0,11875226 ! cilium assembly GO:0042384 37 19 0,000 0,08706525 0,11868498 ! peptide hormone secretion GO:0030072 31 19 0,000 0,08706525 0,11861778 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,09143307 0,124498 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,09143307 0,12442758 ! positive regulation of ossification GO:0045778 47 20 0,000 0,09143307 0,12435724 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,09143307 0,12428698 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,09143307 0,12421681 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,09143307 0,12414671 ! cAMP metabolic process GO:0046058 36 20 0,000 0,09143307 0,12407669 ! response to vitamin GO:0033273 31 20 0,000 0,09143307 0,12400674 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,09143307 0,12393688 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,09143307 0,1238671 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,09143307 0,12379739 ! retinoid metabolic process GO:0001523 32 20 0,000 0,09143307 0,12372776 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,09143307 0,12365821 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,09143307 0,12358874 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,09143307 0,12351935 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,09143307 0,12345004 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,09143307 0,1233808 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,09143307 0,12331164 ! body fluid secretion GO:0007589 31 20 0,000 0,09143307 0,12324256 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,09143307 0,12317355 ! peptide secretion GO:0002790 35 20 0,000 0,09143307 0,12310462 ! stem cell differentiation GO:0048863 53 20 0,000 0,09143307 0,12303577 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,09143307 0,122967 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,09143307 0,1228983 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,09143307 0,12282968 ! sensory perception of pain GO:0019233 30 20 0,000 0,09143307 0,12276114 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,09143307 0,12269267 ! diencephalon development GO:0021536 34 20 0,000 0,09143307 0,12262428 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,09143307 0,12255597 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,09143307 0,12248773 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,09143307 0,12241957 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,09143307 0,12235148 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,09143307 0,12228347 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,09143307 0,12221554 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,09143307 0,12214768 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,09143307 0,12207989 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,09143307 0,12201218 ! regulation of glucose import GO:0046324 29 20 0,000 0,09143307 0,12194455 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,09143307 0,12187699 ! actin filament-based movement GO:0030048 43 20 0,000 0,09143307 0,1218095 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,09143307 0,12174209 ! negative regulation of translation GO:0017148 29 20 0,000 0,09143307 0,12167476 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,09143307 0,1216075 ! regulation of cell killing GO:0031341 42 21 0,000 0,09578013 0,12731879 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,09578013 0,12724848 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,09578013 0,12717826 ! hormone secretion GO:0046879 38 21 0,000 0,09578013 0,12710811 ! glycerol metabolic process GO:0006071 34 21 0,000 0,09578013 0,12703804 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,09578013 0,12696805 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,09578013 0,12689813 ! axis specification GO:0009798 38 21 0,000 0,09578013 0,12682829 ! ovarian follicle development GO:0001541 35 21 0,000 0,09578013 0,12675853 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,09578013 0,12668884 ! smooth muscle contraction GO:0006939 46 21 0,000 0,09578013 0,12661923 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,09578013 0,1265497 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,09578013 0,12648024 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,09578013 0,12641086 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,09578013 0,12634156 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,09578013 0,12627233 ! cytolysis GO:0019835 24 21 0,000 0,09578013 0,12620318 ! vasodilation GO:0042311 39 21 0,000 0,09578013 0,1261341 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,09578013 0,1260651 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,09578013 0,12599617 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,09578013 0,12592732 ! oogenesis GO:0048477 36 21 0,000 0,09578013 0,12585855 ! DNA modification GO:0006304 34 21 0,000 0,09578013 0,12578985 ! collagen fibril organization GO:0030199 59 21 0,000 0,09578013 0,12572122 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,09578013 0,12565267 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,09578013 0,1255842 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,09578013 0,1255158 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,09578013 0,12544747 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,09578013 0,12537922 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,09578013 0,12531104 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,09578013 0,12524294 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,09578013 0,12517491 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,09578013 0,12510695 ! collagen catabolic process GO:0030574 28 21 0,000 0,09578013 0,12503907 ! sperm-egg recognition GO:0035036 21 21 0,000 0,09578013 0,12497126 ! gut development GO:0048565 39 21 0,000 0,09578013 0,12490352 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,10010655 0,13047473 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,10010655 0,13040409 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,10010655 0,13033352 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,10010655 0,13026303 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,10010655 0,13019262 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,10010655 0,13012228 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,10010655 0,13005202 ! regeneration GO:0031099 41 22 0,000 0,10010655 0,12998184 ! keratinization GO:0031424 28 22 0,000 0,10010655 0,12991173 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,10010655 0,1298417 ! sensory perception of taste GO:0050909 28 22 0,000 0,10010655 0,12977174 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,10010655 0,12970186 ! vacuolar transport GO:0007034 36 22 0,000 0,10010655 0,12963205 ! lysosome organization GO:0007040 41 22 0,000 0,10010655 0,12956232 ! central nervous system neuron development GO:0021954 46 22 0,000 0,10010655 0,12949266 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,10010655 0,12942308 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,10010655 0,12935357 ! fucose metabolic process GO:0006004 39 22 0,000 0,10010655 0,12928414 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,10010655 0,12921478 ! ureteric bud development GO:0001657 43 22 0,000 0,10010655 0,12914549 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,10010655 0,12907629 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,10010655 0,12900715 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,10010655 0,12893809 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,10010655 0,1288691 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,10010655 0,12880019 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,10010655 0,12873135 ! sarcomere organization GO:0045214 30 22 0,000 0,10010655 0,12866258 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,10010655 0,12859389 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,10010655 0,12852527 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,10010655 0,12845672 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,10010655 0,12838825 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,10010655 0,12831984 ! protein stabilization GO:0050821 39 22 0,000 0,10010655 0,12825152 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,1044124 0,13369677 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,1044124 0,13362565 ! gluconeogenesis GO:0006094 33 23 0,000 0,1044124 0,13355462 ! viral genome replication GO:0019079 41 23 0,000 0,1044124 0,13348365 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,1044124 0,13341276 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,1044124 0,13334195 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,1044124 0,13327121 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,1044124 0,13320055 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,1044124 0,13312996 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,1044124 0,13305944 ! visual behavior GO:0007632 42 23 0,000 0,1044124 0,13298901 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,1044124 0,13291864 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,1044124 0,13284835 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,1044124 0,13277813 ! peroxisome organization GO:0007031 37 23 0,000 0,1044124 0,13270799 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,1044124 0,13263793 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,1044124 0,13256793 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,1044124 0,13249801 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,1044124 0,13242817 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,1044124 0,13235839 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,1044124 0,13228869 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,1044124 0,13221907 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,1044124 0,13214952 ! fatty acid transport GO:0015908 44 23 0,000 0,1044124 0,13208004 ! platelet activation GO:0030168 37 23 0,000 0,1044124 0,13201063 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,1044124 0,1319413 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,1044124 0,13187204 ! hormone transport GO:0009914 40 23 0,000 0,1044124 0,13180285 ! cell-cell recognition GO:0009988 25 23 0,000 0,1044124 0,13173373 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,1044124 0,13166469 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,1044124 0,13159572 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,1044124 0,13152682 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,1044124 0,131458 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,10869779 0,13678184 GO:0016444|somatic cell DNA recombination, ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10869779 0,13671034 ! vesicle docking GO:0048278 47 24 0,000 0,10869779 0,13663892 ! spinal cord development GO:0021510 47 24 0,000 0,10869779 0,13656756 ! vacuole organization GO:0007033 43 24 0,000 0,10869779 0,13649629 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,10869779 0,13642508 ! digestive system process GO:0022600 39 24 0,000 0,10869779 0,13635396 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,10869779 0,1362829 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,10869779 0,13621192 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,10869779 0,13614101 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,10869779 0,13607018 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,10869779 0,13599942 GO:0002708|positive regulation of lymphocyte mediated immunity, ! membrane depolarization GO:0051899 39 24 0,000 0,10869779 0,13592874 ! pallium development GO:0021543 49 24 0,000 0,10869779 0,13585812 ! pentose metabolic process GO:0019321 35 24 0,000 0,10869779 0,13578758 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,10869779 0,13571712 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10869779 0,13564673 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10869779 0,13557641 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10869779 0,13550616 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10869779 0,13543598 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,10869779 0,13536588 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10869779 0,13529585 ! myelination GO:0042552 45 25 0,000 0,11296282 0,14053182 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,11296282 0,1404592 ! phototransduction GO:0007602 33 25 0,000 0,11296282 0,14038665 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,11296282 0,14031417 ! receptor metabolic process GO:0043112 46 25 0,000 0,11296282 0,14024177 ! chromosome condensation GO:0030261 45 25 0,000 0,11296282 0,14016944 ! osteoblast differentiation GO:0001649 60 25 0,000 0,11296282 0,14009719 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,11296282 0,14002501 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,11296282 0,13995291 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,11296282 0,13988088 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,11296282 0,13980892 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,11296282 0,13973704 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,11296282 0,13966523 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,11296282 0,1395935 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,11296282 0,13952184 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,11296282 0,13945025 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,11296282 0,13937874 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,11296282 0,1393073 ! telomere organization GO:0032200 43 25 0,000 0,11296282 0,13923594 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,11296282 0,13916464 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,11296282 0,13909342 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,11720758 0,14424626 ! embryonic pattern specification GO:0009880 44 26 0,000 0,11720758 0,14417252 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,11720758 0,14409885 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,11720758 0,14402525 ! initiation of viral infection GO:0019059 57 26 0,000 0,11720758 0,14395173 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,11720758 0,14387829 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,11720758 0,14380492 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,11720758 0,14373162 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,11720758 0,1436584 ! molting cycle process GO:0022404 50 26 0,000 0,11720758 0,14358526 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,11720758 0,14351218 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,11720758 0,14343919 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,11720758 0,14336626 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,11720758 0,14329342 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,11720758 0,14322064 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,11720758 0,14314794 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,11720758 0,14307531 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,11720758 0,14300276 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,11720758 0,14293028 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,11720758 0,14285787 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,11720758 0,14278554 ! blastocyst development GO:0001824 49 26 0,000 0,11720758 0,14271328 ! leukocyte proliferation GO:0070661 52 26 0,000 0,11720758 0,14264109 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,11720758 0,14256898 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,11720758 0,14249694 ! neuron fate commitment GO:0048663 48 27 0,000 0,12143217 0,14755849 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,12143217 0,147484 ! iron ion transport GO:0006826 59 27 0,000 0,12143217 0,14740959 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,12143217 0,14733525 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,12143217 0,14726099 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,12143217 0,1471868 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,12143217 0,14711269 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,12143217 0,14703865 ! autophagy GO:0006914 41 27 0,000 0,12143217 0,14696469 ! male gonad development GO:0008584 44 27 0,000 0,12143217 0,1468908 ! response to toxin GO:0009636 47 27 0,000 0,12143217 0,14681699 ! primary neural tube formation GO:0014020 51 27 0,000 0,12143217 0,14674325 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,12143217 0,14666958 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,12143217 0,14659599 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,12143217 0,14652247 ! glutathione metabolic process GO:0006749 39 27 0,000 0,12143217 0,14644902 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,12143217 0,14637565 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,12143217 0,14630235 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,12143217 0,14622913 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,12563668 0,15121654 ! circadian rhythm GO:0007623 50 28 0,000 0,12563668 0,15114093 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,12563668 0,1510654 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,12563668 0,15098994 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,12563668 0,15091456 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,12563668 0,15083925 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,12563668 0,15076402 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,12563668 0,15068886 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,12563668 0,15061378 ! synaptogenesis GO:0007416 42 28 0,000 0,12563668 0,15053877 ! lipid oxidation GO:0034440 43 28 0,000 0,12563668 0,15046384 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,12563668 0,15038898 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,12563668 0,1503142 ! translational initiation GO:0006413 65 29 0,000 0,12982121 0,15524346 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,12982121 0,15516634 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,12982121 0,15508929 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,12982121 0,15501233 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,12982121 0,15493544 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,12982121 0,15485862 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,12982121 0,15478188 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,12982121 0,15470522 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,12982121 0,15462863 ! cell fate determination GO:0001709 60 29 0,000 0,12982121 0,15455212 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,12982121 0,15447569 ! detection of light stimulus GO:0009583 38 29 0,000 0,12982121 0,15439933 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,12982121 0,15432304 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,12982121 0,15424683 ! tissue homeostasis GO:0001894 48 29 0,000 0,12982121 0,1541707 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,12982121 0,15409464 ! zinc ion transport GO:0006829 45 30 0,000 0,13398585 0,15895955 ! membrane docking GO:0022406 61 30 0,000 0,13398585 0,15888121 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,13398585 0,15880294 ! cell junction assembly GO:0034329 78 30 0,000 0,13398585 0,15872475 ! regulation of innate immune response GO:0045088 51 30 0,000 0,13398585 0,15864664 ! acute-phase response GO:0006953 49 30 0,000 0,13398585 0,1585686 ! myofibril assembly GO:0030239 47 30 0,000 0,13398585 0,15849064 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,13398585 0,15841276 ! phospholipid transport GO:0015914 51 30 0,000 0,13398585 0,15833495 ! ensheathment of neurons GO:0007272 57 30 0,000 0,13398585 0,15825722 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,13398585 0,15817957 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,13398585 0,15810199 ! eye morphogenesis GO:0048592 60 30 0,000 0,13398585 0,15802449 ! response to heat GO:0009408 50 30 0,000 0,13398585 0,15794707 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,1381307 0,16275341 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,1381307 0,16267375 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,1381307 0,16259416 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,1381307 0,16251466 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,1381307 0,16243522 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,1381307 0,16235587 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,1381307 0,1622766 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,1381307 0,1621974 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,1381307 0,16211828 ! peptide transport GO:0015833 55 31 0,000 0,1381307 0,16203923 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,1381307 0,16196027 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,1381307 0,16188138 ! mesoderm formation GO:0001707 69 31 0,000 0,1381307 0,16180257 ! natural killer cell activation GO:0030101 45 31 0,000 0,1381307 0,16172383 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,1381307 0,16164517 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,1381307 0,16156659 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,1381307 0,16148808 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,1381307 0,16140965 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,14225585 0,16614931 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,14225585 0,16606869 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,14225585 0,16598815 ! cholesterol transport GO:0030301 56 32 0,000 0,14225585 0,16590769 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,14225585 0,16582731 ! spliceosome assembly GO:0000245 67 32 0,000 0,14225585 0,16574701 ! spindle organization GO:0007051 46 32 0,000 0,14225585 0,16566678 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,14225585 0,16558663 ! metanephros development GO:0001656 74 32 0,000 0,14225585 0,16550656 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,14225585 0,16542657 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,14225585 0,16534665 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,14225585 0,16526682 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,14225585 0,16518705 ! muscle cell development GO:0055001 49 32 0,000 0,14225585 0,16510737 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,14225585 0,16502776 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,14225585 0,16494823 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,14225585 0,16486877 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,14225585 0,1647894 ! peripheral nervous system development GO:0007422 64 32 0,000 0,14225585 0,16471009 ! BMP signaling pathway GO:0030509 64 32 0,000 0,14225585 0,16463087 ! hindbrain development GO:0030902 61 32 0,000 0,14225585 0,16455172 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,14225585 0,16447264 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,14225585 0,16439365 ! gene silencing GO:0016458 65 32 0,000 0,14225585 0,16431473 ! post-embryonic development GO:0009791 69 33 0,000 0,14636139 0,16897577 ! protein targeting to membrane GO:0006612 68 33 0,000 0,14636139 0,16889473 ! ceramide metabolic process GO:0006672 64 33 0,000 0,14636139 0,16881376 ! formation of primary germ layer GO:0001704 72 33 0,000 0,14636139 0,16873287 ! cell fate specification GO:0001708 52 33 0,000 0,14636139 0,16865206 ! sterol transport GO:0015918 57 33 0,000 0,14636139 0,16857133 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,14636139 0,16849067 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,14636139 0,16841009 ! adult locomotory behavior GO:0008344 59 33 0,000 0,14636139 0,16832959 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,14636139 0,16824916 ! glial cell differentiation GO:0010001 63 34 0,000 0,15044741 0,17286365 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,15044741 0,17278113 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,15044741 0,1726987 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,15044741 0,17261635 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,15044741 0,17253407 ! mismatch repair GO:0006298 46 34 0,000 0,15044741 0,17245187 ! spermatid development GO:0007286 63 34 0,000 0,15044741 0,17236975 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,15044741 0,17228771 ! regulation of muscle development GO:0048634 70 35 0,000 0,15451402 0,17686048 ! negative regulation of secretion GO:0051048 63 35 0,000 0,15451402 0,17677638 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,15451402 0,17669236 ! odontogenesis GO:0042476 66 35 0,000 0,15451402 0,17660842 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,15451402 0,17652456 ! female gonad development GO:0008585 58 35 0,000 0,15451402 0,17644078 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,15451402 0,17635708 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,15451402 0,17627346 ! cytokine production GO:0001816 59 35 0,000 0,15451402 0,17618991 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,15451402 0,17610645 ! neural tube formation GO:0001841 67 35 0,000 0,15451402 0,17602307 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,15856129 0,18054825 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,15856129 0,18046284 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,15856129 0,18037752 ! cell junction organization GO:0034330 86 36 0,000 0,15856129 0,18029227 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,15856129 0,18020711 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,15856129 0,18012203 ! regulation of proteolysis GO:0030162 72 36 0,000 0,15856129 0,18003702 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,15856129 0,1799521 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,15856129 0,17986726 ! aerobic respiration GO:0009060 55 36 0,000 0,15856129 0,17978249 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,15856129 0,17969781 ! RNA export from nucleus GO:0006405 56 37 0,000 0,16258932 0,18417603 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,16258932 0,18408936 ! meiosis I GO:0007127 65 37 0,000 0,16258932 0,18400277 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,16258932 0,18391626 ! sister chromatid segregation GO:0000819 58 37 0,000 0,16258932 0,18382984 ! actomyosin structure organization GO:0031032 62 37 0,000 0,16258932 0,18374349 ! organic anion transport GO:0015711 68 37 0,000 0,16258932 0,18365723 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,16258932 0,18357104 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,16258932 0,18348494 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,16258932 0,18339892 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,16258932 0,18331298 ! pigment metabolic process GO:0042440 80 37 0,000 0,16258932 0,18322712 ! spermatid differentiation GO:0048515 66 37 0,000 0,16258932 0,18314134 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,1665982 0,18756914 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,1665982 0,18748141 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,1665982 0,18739376 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,1665982 0,1873062 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,1665982 0,18721871 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,1665982 0,18713131 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,1665982 0,18704399 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,1665982 0,18695674 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,1665982 0,18686959 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,1665982 0,18678251 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,1665982 0,18669551 ! glucan metabolic process GO:0044042 62 38 0,000 0,1665982 0,18660859 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,17058802 0,19098873 ! mammary gland development GO:0030879 86 39 0,000 0,17058802 0,19089989 ! ear morphogenesis GO:0042471 60 39 0,000 0,17058802 0,19081114 ! organic ether metabolic process GO:0018904 55 39 0,000 0,17058802 0,19072248 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,17058802 0,19063389 ! ion transmembrane transport GO:0034220 66 39 0,000 0,17058802 0,19054539 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,17058802 0,19045697 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,17058802 0,19036863 ! RNA modification GO:0009451 57 39 0,000 0,17058802 0,19028038 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,17058802 0,1901922 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,17455887 0,19452925 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,17455887 0,19443919 ! feeding behavior GO:0007631 59 40 0,000 0,17455887 0,19434921 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,17455887 0,19425932 ! maintenance of protein location GO:0045185 91 40 0,000 0,17455887 0,19416951 ! cytokinesis GO:0000910 72 40 0,000 0,17455887 0,19407978 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,17851085 0,19838203 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,17851085 0,19829044 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,17851085 0,19819894 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,17851085 0,19810752 ! female gamete generation GO:0007292 61 41 0,000 0,17851085 0,19801618 ! polyol metabolic process GO:0019751 66 41 0,000 0,17851085 0,19792493 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,17851085 0,19783376 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,18244403 0,2020996 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,18244403 0,2020066 ! regulation of tube size GO:0035150 71 42 0,000 0,18244403 0,20191368 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,18244403 0,20182084 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,18244403 0,2017281 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,18244403 0,20163543 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,18244403 0,20154285 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,18244403 0,20145036 ! neuron migration GO:0001764 79 42 0,000 0,18244403 0,20135795 ! regulation of protein secretion GO:0050708 71 42 0,000 0,18244403 0,20126563 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,18635851 0,20548973 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,18635851 0,20539559 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,18635851 0,20530155 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,18635851 0,20520759 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,18635851 0,20511371 ! glucose transport GO:0015758 65 43 0,000 0,18635851 0,20501993 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,18635851 0,20492622 ! neural tube development GO:0021915 77 43 0,000 0,18635851 0,20483261 ! striated muscle contraction GO:0006941 77 43 0,000 0,18635851 0,20473908 ! phagocytosis GO:0006909 90 43 0,000 0,18635851 0,20464563 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,18635851 0,20455227 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,19025438 0,20873326 ! hexose transport GO:0008645 67 44 0,000 0,19025438 0,20863812 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,19025438 0,20854307 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,19025438 0,20844811 ! developmental growth GO:0048589 82 44 0,000 0,19025438 0,20835323 ! maintenance of location in cell GO:0051651 97 44 0,000 0,19025438 0,20825844 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,19413173 0,21240606 ! glycolysis GO:0006096 65 45 0,000 0,19413173 0,21230951 ! leukocyte migration GO:0050900 68 45 0,000 0,19413173 0,21221305 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,19413173 0,21211668 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,19413173 0,2120204 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,19413173 0,2119242 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,19413173 0,21182809 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,19413173 0,21173206 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,19413173 0,21163613 ! cell growth GO:0016049 84 45 0,000 0,19413173 0,21154028 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,19799063 0,21564756 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,19799063 0,21554998 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,19799063 0,21545249 ! pigmentation GO:0043473 100 46 0,000 0,19799063 0,21535509 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,19799063 0,21525778 ! positive regulation of defense response GO:0031349 76 47 0,000 0,20183119 0,21933416 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,20183119 0,21923514 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,20183119 0,21913621 ! JNK cascade GO:0007254 91 47 0,000 0,20183119 0,21903736 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,20183119 0,21893861 ! protein homooligomerization GO:0051260 76 47 0,000 0,20183119 0,21883994 ! Notch signaling pathway GO:0007219 96 48 0,000 0,20565348 0,22288391 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,20565348 0,22278355 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,20565348 0,22268329 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,20565348 0,22258312 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,20945759 0,22659846 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,20945759 0,22649662 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,20945759 0,22639486 ! regulation of ion transport GO:0043269 77 49 0,000 0,20945759 0,22629321 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,20945759 0,22619164 ! peptide metabolic process GO:0006518 76 49 0,000 0,20945759 0,22609016 ! response to temperature stimulus GO:0009266 76 49 0,000 0,20945759 0,22598878 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,20945759 0,22588748 ! endocrine system development GO:0035270 104 49 0,000 0,20945759 0,22578628 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,20945759 0,22568516 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,20945759 0,22558414 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,20945759 0,22548321 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,20945759 0,22538237 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,21324361 0,22935366 ! neuromuscular process GO:0050905 99 50 0,000 0,21324361 0,22925118 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,21324361 0,22914879 ! viral infectious cycle GO:0019058 99 51 0,000 0,21701163 0,23309374 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,21701163 0,23298973 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,21701163 0,23288581 ! excretion GO:0007588 83 51 0,000 0,21701163 0,23278198 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,21701163 0,23267825 ! vesicle organization GO:0016050 107 51 0,000 0,21701163 0,2325746 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,21701163 0,23247105 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,22076172 0,23638305 ! membrane fusion GO:0006944 110 52 0,000 0,22076172 0,2362779 ! amino acid activation GO:0043038 92 52 0,000 0,22076172 0,23617284 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,22076172 0,23606787 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,22449398 0,23995225 ! RNA catabolic process GO:0006401 93 53 0,000 0,22449398 0,2398457 ! regulation of translational initiation GO:0006446 82 53 0,000 0,22449398 0,23973925 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,22449398 0,23963288 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,22449398 0,23952662 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,22449398 0,23942044 ! cell maturation GO:0048469 100 53 0,000 0,22449398 0,23931436 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,22449398 0,23920838 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,22820849 0,24305871 ! cell recognition GO:0008037 85 54 0,000 0,22820849 0,24295116 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,22820849 0,24284371 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,22820849 0,24273635 ! chloride transport GO:0006821 90 55 0,000 0,23190532 0,24655952 ! glucose catabolic process GO:0006007 82 55 0,000 0,23190532 0,24645062 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,23190532 0,24634181 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,23190532 0,2462331 ! gastrulation GO:0007369 112 55 0,000 0,23190532 0,24612448 ! RNA elongation GO:0006354 79 55 0,000 0,23190532 0,24601596 ! nuclear export GO:0051168 97 55 0,000 0,23190532 0,24590754 ! regulation of actin filament length GO:0030832 105 56 0,000 0,23558457 0,24969889 ! sensory perception of smell GO:0007608 80 56 0,000 0,23558457 0,24958894 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,23558457 0,24947909 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,23558457 0,24936933 ! proton transport GO:0015992 94 56 0,000 0,23558457 0,24925967 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,23558457 0,2491501 ! muscle fiber development GO:0048747 112 57 0,000 0,23924632 0,25291153 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,23924632 0,25280046 ! maintenance of location GO:0051235 118 57 0,000 0,23924632 0,25268949 ! hydrogen transport GO:0006818 97 58 0,000 0,24289065 0,25642602 ! positive regulation of secretion GO:0051047 95 59 0,000 0,24651764 0,26014099 ! regulation of cellular component size GO:0032535 109 59 0,000 0,24651764 0,26002694 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,24651764 0,25991299 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,24651764 0,25979914 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,24651764 0,2596854 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,24651764 0,25957175 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,25012738 0,26325742 ! camera-type eye development GO:0043010 116 60 0,000 0,25012738 0,26314231 ! kidney development GO:0001822 122 60 0,000 0,25012738 0,2630273 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,25371994 0,26668859 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,25371994 0,26657213 ! mesoderm development GO:0007498 119 61 0,000 0,25371994 0,26645577 ! tRNA processing GO:0008033 89 61 0,000 0,25371994 0,26633952 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,25371994 0,26622337 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,25729541 0,26985735 ! gonad development GO:0008406 98 62 0,000 0,25729541 0,26973976 ! regulation of mitosis GO:0007088 105 63 0,000 0,26085387 0,27335122 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,26085387 0,27323222 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,26085387 0,27311332 ! detection of external stimulus GO:0009581 91 63 0,000 0,26085387 0,27299452 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,26085387 0,27287583 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,2643954 0,27646038 ! cell redox homeostasis GO:0045454 102 64 0,000 0,2643954 0,27634028 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,2643954 0,27622029 ! single fertilization GO:0007338 75 64 0,000 0,2643954 0,2761004 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,26792007 0,27965974 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,26792007 0,27953846 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,26792007 0,27941729 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,26792007 0,27929623 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,27142797 0,28283054 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,27142797 0,2827081 ! extracellular matrix organization GO:0030198 133 66 0,000 0,27142797 0,28258577 ! secondary metabolic process GO:0019748 116 66 0,000 0,27142797 0,28246354 ! developmental maturation GO:0021700 116 66 0,000 0,27142797 0,28234142 ! cell projection assembly GO:0030031 120 66 0,000 0,27142797 0,28221941 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,27491919 0,28572594 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,27491919 0,28560257 ! chromosome segregation GO:0007059 113 67 0,000 0,27491919 0,28547931 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,27491919 0,28535615 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,27491919 0,2852331 ! hexose catabolic process GO:0019320 104 67 0,000 0,27491919 0,28511015 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,27491919 0,28498732 ! activation of immune response GO:0002253 105 67 0,000 0,27491919 0,28486458 ! amino acid transport GO:0006865 125 68 0,000 0,27839378 0,2883407 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,27839378 0,28821663 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,27839378 0,28809266 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,28185184 0,2915458 ! urogenital system development GO:0001655 137 69 0,000 0,28185184 0,29142051 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,28185184 0,29129533 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,28185184 0,29117026 ! antigen processing and presentation GO:0019882 104 69 0,000 0,28185184 0,29104529 ! appendage morphogenesis GO:0035107 135 70 0,000 0,28529345 0,29447277 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,28871867 0,29788042 ! reproductive structure development GO:0048608 113 71 0,000 0,28871867 0,29775273 ! appendage development GO:0048736 136 71 0,000 0,28871867 0,29762516 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,28871867 0,2974977 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,28871867 0,29737035 ! regulation of immune effector process GO:0002697 137 71 0,000 0,28871867 0,2972431 ! acute inflammatory response GO:0002526 113 72 0,000 0,2921276 0,30062404 ! carbohydrate transport GO:0008643 110 72 0,000 0,2921276 0,30049551 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,2955203 0,30385548 ! axon guidance GO:0007411 139 73 0,000 0,2955203 0,30372569 ! fertilization GO:0009566 90 73 0,000 0,2955203 0,303596 ! transition metal ion transport GO:0000041 126 74 0,000 0,29889685 0,30693376 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,29889685 0,30680282 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,29889685 0,30667199 ! eye development GO:0001654 143 74 0,000 0,29889685 0,30654127 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,30225732 0,30985561 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,30225732 0,30972365 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,30225732 0,30959179 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,30560181 0,31288423 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,30560181 0,31275115 ! defense response to bacterium GO:0042742 89 76 0,000 0,30560181 0,31261817 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,30560181 0,31248532 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,30560181 0,31235257 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,30893037 0,31562058 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,30893037 0,31548662 ! blood coagulation GO:0007596 146 78 0,000 0,31224309 0,31873435 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,31224309 0,31859918 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,31554003 0,32182676 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,31554003 0,32169039 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,31882129 0,32489793 ! muscle cell differentiation GO:0042692 159 80 0,000 0,31882129 0,32476038 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,31882129 0,32462294 ! inorganic anion transport GO:0015698 138 80 0,000 0,31882129 0,32448562 ! digestion GO:0007586 112 81 0,000 0,32208692 0,32767066 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,32208692 0,32753217 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,32208692 0,3273938 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,32208692 0,32725554 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,325337 0,33041824 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,325337 0,33027883 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,325337 0,33013953 ! regulation of lyase activity GO:0051339 160 83 0,000 0,32857161 0,33328132 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,33179081 0,33640485 ! hemostasis GO:0007599 158 84 0,000 0,33179081 0,33626314 ! negative regulation of transport GO:0051051 153 84 0,000 0,33179081 0,33612156 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,33818332 0,34245331 ! alcohol catabolic process GO:0046164 130 86 0,000 0,33818332 0,34230924 ! amine transport GO:0015837 155 86 0,000 0,33818332 0,34216529 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,34135676 0,34523092 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,34135676 0,34508587 ! regulation of protein transport GO:0051223 154 87 0,000 0,34135676 0,34494093 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,34451509 0,34798627 ! gland development GO:0048732 206 88 0,000 0,34451509 0,34784024 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,34451509 0,34769434 ! cellular defense response GO:0006968 114 89 0,000 0,34765838 0,35071952 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,3507867 0,35372707 ! sex differentiation GO:0007548 145 90 0,000 0,3507867 0,35357888 ! sterol metabolic process GO:0016125 152 91 0,000 0,35390012 0,35656771 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,35390012 0,35641845 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,35699871 0,35938866 ! vitamin metabolic process GO:0006766 139 92 0,000 0,35699871 0,35923835 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,36008255 0,36219006 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,36008255 0,3620387 ! forebrain development GO:0030900 188 95 0,000 0,36620623 0,36804185 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,36620623 0,36788818 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,36924621 0,3707873 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,36924621 0,37063262 ! positive regulation of immune response GO:0050778 156 96 0,000 0,36924621 0,37047806 ! detection of stimulus GO:0051606 151 96 0,000 0,36924621 0,37032363 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,37227171 0,37320239 ! protein ubiquitination GO:0016567 217 97 0,000 0,37227171 0,37304695 ! hormone metabolic process GO:0042445 157 97 0,000 0,37227171 0,37289165 ! regulation of protein localization GO:0032880 176 97 0,000 0,37227171 0,37273647 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,3752828 0,37559501 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,3752828 0,37543884 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,37827954 0,37827954