pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1114-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 224 98 10,000 8,106E-13 1,98E-09 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 8,000 4,273E-12 5,22E-09 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 7,000 3,032E-11 2,469E-08 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 4,000 9,315E-11 5,689E-08 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 4,000 4,161E-10 2,033E-07 ! auditory receptor cell differentiation GO:0042491 36 17 4,000 9,963E-09 4,057E-06 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 3,000 2,661E-08 9,288E-06 ! lung development GO:0030324 165 69 6,000 2,683E-08 8,194E-06 ! respiratory tube development GO:0030323 171 72 6,000 3,623E-08 9,833E-06 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 4,000 4,164E-08 1,017E-05 ! inner ear receptor cell differentiation GO:0060113 42 22 4,000 4,164E-08 9,248E-06 ! respiratory system development GO:0060541 175 74 6,000 4,392E-08 8,942E-06 ! mechanoreceptor differentiation GO:0042490 48 24 4,000 6,673E-08 1,254E-05 ! negative regulation of phosphorylation GO:0042326 52 24 4,000 6,673E-08 1,164E-05 ! response to hypoxia GO:0001666 178 81 6,000 8,268E-08 1,347E-05 ! response to oxygen levels GO:0070482 183 83 6,000 9,799E-08 1,496E-05 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 4,000 1,025E-07 1,473E-05 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of cell motion GO:0051272 157 65 5,000 4,841E-07 6,57E-05 ! cell cycle checkpoint GO:0000075 145 71 5,000 8,21E-07 1,056E-04 ! mitotic cell cycle checkpoint GO:0007093 76 39 4,000 8,562E-07 1,046E-04 ! positive regulation of glycolysis GO:0045821 13 5 2,000 8,726E-07 1,015E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 1,767E-06 1,962E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 1,778E-06 1,889E-04 ! negative regulation of growth GO:0045926 168 85 5,000 2,381E-06 2,424E-04 ! N-terminal protein amino acid acetylation GO:0006474 14 7 2,000 3,034E-06 2,965E-04 ! inner ear development GO:0048839 89 53 4,000 4,058E-06 3,813E-04 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 3,000 4,533E-06 4,101E-04 ! response to UV GO:0009411 120 55 4,000 4,883E-06 4,261E-04 ! positive regulation of cell migration GO:0030335 137 58 4,000 6,363E-06 5,36E-04 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 7,234E-06 5,891E-04 ! regulation of glycolysis GO:0006110 20 9 2,000 7,234E-06 5,701E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 7,234E-06 5,523E-04 ! regulation of fibroblast proliferation GO:0048145 56 28 3,000 7,26E-06 5,375E-04 ! DNA damage response, signal transduction GO:0042770 136 62 4,000 8,858E-06 6,365E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 1,03E-05 7,19E-04 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 2,000 1,03E-05 6,99E-04 GO:0043470|regulation of carbohydrate catabolic process, ! cellular response to extracellular stimulus GO:0031668 52 31 3,000 1,104E-05 7,29E-04 ! ear development GO:0043583 114 66 4,000 1,206E-05 7,752E-04 ! steroid hormone receptor signaling pathway GO:0030518 146 66 4,000 1,206E-05 7,553E-04 ! negative regulation of cell growth GO:0030308 142 67 4,000 1,298E-05 7,93E-04 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 1,412E-05 8,411E-04 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 2,000 1,412E-05 8,211E-04 ! peptide or protein amino-terminal blocking GO:0018409 22 11 2,000 1,412E-05 8,02E-04 ! negative regulation of cell size GO:0045792 144 69 4,000 1,5E-05 8,329E-04 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 4,000 1,725E-05 9,367E-04 ! DNA damage checkpoint GO:0000077 78 35 3,000 1,812E-05 9,622E-04 ! positive regulation of cellular catabolic process GO:0031331 34 12 2,000 1,876E-05 9,751E-04 ! regulation of B cell proliferation GO:0030888 22 12 2,000 1,876E-05 9,548E-04 ! histone acetylation GO:0016573 27 12 2,000 1,876E-05 9,353E-04 ! peptidyl-lysine modification GO:0018205 21 12 2,000 1,876E-05 9,166E-04 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 2,000 2,431E-05 1,164E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 2,000 2,431E-05 1,142E-03 ! regulation of erythrocyte differentiation GO:0045646 47 13 2,000 2,431E-05 1,12E-03 ! DNA integrity checkpoint GO:0031570 82 38 3,000 2,528E-05 1,144E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 3,084E-05 1,37E-03 ! positive regulation of phosphorylation GO:0042327 149 81 4,000 3,275E-05 1,429E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 3,685E-05 1,579E-03 GO:0045937|positive regulation of phosphate metabolic process, ! N-terminal protein amino acid modification GO:0031365 30 15 2,000 3,842E-05 1,618E-03 ! G1/S transition checkpoint GO:0031575 37 15 2,000 3,842E-05 1,591E-03 ! cellular response to hormone stimulus GO:0032870 182 85 4,000 4,133E-05 1,683E-03 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 4,713E-05 1,887E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 4,979E-05 1,962E-03 ! regulation of gene-specific transcription GO:0032583 102 46 3,000 5,435E-05 2,107E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 4,000 6,364E-05 2,429E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 6,435E-05 2,419E-03 ! patterning of blood vessels GO:0001569 43 18 2,000 6,822E-05 2,525E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 6,822E-05 2,488E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 2,000 6,822E-05 2,451E-03 ! G1 phase of mitotic cell cycle GO:0000080 39 19 2,000 8,075E-05 2,859E-03 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 2,000 8,075E-05 2,818E-03 ! histone modification GO:0016570 104 52 3,000 8,83E-05 3,038E-03 ! positive regulation of angiogenesis GO:0045766 50 20 2,000 9,469E-05 3,213E-03 ! protein amino acid acetylation GO:0006473 41 20 2,000 9,469E-05 3,169E-03 ! regulation of carbohydrate metabolic process GO:0006109 37 20 2,000 9,469E-05 3,126E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! positive regulation of growth GO:0045927 96 53 3,000 9,518E-05 3,1E-03 ! covalent chromatin modification GO:0016569 115 54 3,000 1,024E-04 3,293E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 1,101E-04 3,493E-03 ! regulation of DNA replication GO:0006275 105 56 3,000 1,181E-04 3,7E-03 ! G1 phase GO:0051318 44 22 2,000 1,271E-04 3,93E-03 ! regulation of cell-matrix adhesion GO:0001952 81 23 2,000 1,457E-04 4,448E-03 GO:0010810|regulation of cell-substrate adhesion, ! regulation of cellular catabolic process GO:0031329 55 24 2,000 1,659E-04 5,004E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 1,659E-04 4,943E-03 ! regulation of homeostatic process GO:0032844 148 62 3,000 1,757E-04 5,173E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 1,879E-04 5,465E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 1,879E-04 5,401E-03 ! protein tetramerization GO:0051262 57 25 2,000 1,879E-04 5,338E-03 ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 1,971E-04 5,535E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,971E-04 5,472E-03 ! 2-oxoglutarate metabolic process GO:0006103 10 5 1,000 1,971E-04 5,41E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 1,971E-04 5,35E-03 ! valine metabolic process GO:0006573 12 5 1,000 1,971E-04 5,291E-03 ! mRNA transcription GO:0009299 10 5 1,000 1,971E-04 5,234E-03 ! response to food GO:0032094 6 5 1,000 1,971E-04 5,178E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 1,971E-04 5,123E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,971E-04 5,069E-03 ! G2/M transition checkpoint GO:0031576 8 5 1,000 1,971E-04 5,016E-03 GO:0031572|G2/M transition DNA damage checkpoint, ! negative regulation of interleukin-6 production GO:0032715 5 5 1,000 1,971E-04 4,964E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 1,971E-04 4,913E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 1,971E-04 4,864E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,971E-04 4,815E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 1,971E-04 4,768E-03 ! stem cell division GO:0017145 11 5 1,000 1,971E-04 4,721E-03 GO:0048103|somatic stem cell division, ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 2,117E-04 5,022E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 2,117E-04 4,974E-03 ! activation of MAPK activity GO:0000187 124 67 3,000 2,373E-04 5,522E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 2,374E-04 5,472E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 2,374E-04 5,421E-03 ! cellular response to nutrient levels GO:0031669 45 27 2,000 2,374E-04 5,371E-03 ! protein amino acid acylation GO:0043543 59 28 2,000 2,65E-04 5,94E-03 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 2,65E-04 5,886E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 2,658E-04 5,85E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 2,81E-04 6,128E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 2,947E-04 6,37E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 2,948E-04 6,317E-03 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 2,948E-04 6,262E-03 ! positive regulation of neuroblast proliferation GO:0002052 13 6 1,000 2,948E-04 6,208E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 2,948E-04 6,155E-03 ! embryonic hemopoiesis GO:0035162 16 6 1,000 2,948E-04 6,103E-03 ! oxygen homeostasis GO:0032364 10 6 1,000 2,948E-04 6,052E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 2,948E-04 6,001E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 2,948E-04 5,952E-03 ! negative regulation of B cell activation GO:0050869 14 6 1,000 2,948E-04 5,903E-03 ! regulation of B cell activation GO:0050864 55 30 2,000 3,263E-04 6,481E-03 ! regulation of caspase activity GO:0043281 136 74 3,000 3,477E-04 6,851E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 3,000 3,477E-04 6,796E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 3,477E-04 6,742E-03 ! positive regulation of catabolic process GO:0009896 72 32 2,000 3,961E-04 7,619E-03 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 4,047E-04 7,725E-03 ! regulation of catabolic process GO:0009894 173 77 3,000 4,047E-04 7,665E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 4,115E-04 7,733E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 4,115E-04 7,674E-03 ! mRNA stabilization GO:0048255 18 7 1,000 4,115E-04 7,616E-03 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 16 7 1,000 4,115E-04 7,558E-03 GO:0031958|corticosteroid receptor signaling pathway, ! oxaloacetate metabolic process GO:0006107 13 7 1,000 4,115E-04 7,502E-03 ! positive regulation of heart rate GO:0010460 11 7 1,000 4,115E-04 7,446E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 1,000 4,115E-04 7,392E-03 ! male sex determination GO:0030238 15 7 1,000 4,115E-04 7,338E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 4,115E-04 7,284E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 4,115E-04 7,232E-03 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 1,000 4,115E-04 7,18E-03 ! regulation of interleukin-1 beta production GO:0032651 11 7 1,000 4,115E-04 7,129E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 4,115E-04 7,079E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 4,115E-04 7,03E-03 ! dopamine biosynthetic process GO:0042416 18 7 1,000 4,115E-04 6,981E-03 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 1,000 4,115E-04 6,933E-03 ! positive regulation of gene-specific transcription GO:0043193 70 33 2,000 4,342E-04 7,266E-03 ! regulation of peptidase activity GO:0052547 150 82 3,000 5,141E-04 8,544E-03 ! male meiosis GO:0007140 9 8 1,000 5,47E-04 9,03E-03 ! succinate metabolic process GO:0006105 17 8 1,000 5,47E-04 8,969E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 5,47E-04 8,909E-03 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 1,000 5,47E-04 8,85E-03 ! hemoglobin metabolic process GO:0020027 14 8 1,000 5,47E-04 8,792E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 5,47E-04 8,735E-03 ! ER overload response GO:0006983 13 8 1,000 5,47E-04 8,678E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 5,47E-04 8,622E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 5,47E-04 8,567E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 5,47E-04 8,512E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 5,47E-04 8,458E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 5,47E-04 8,405E-03 ! gas homeostasis GO:0033483 14 8 1,000 5,47E-04 8,353E-03 ! regulation of interleukin-1 production GO:0032652 14 8 1,000 5,47E-04 8,301E-03 ! response to tumor cell GO:0002347 16 8 1,000 5,47E-04 8,249E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 5,47E-04 8,199E-03 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 1,000 5,47E-04 8,149E-03 ! behavioral response to nicotine GO:0035095 12 8 1,000 5,47E-04 8,099E-03 ! negative regulation of hydrolase activity GO:0051346 66 36 2,000 5,627E-04 8,281E-03 ! tissue remodeling GO:0048771 78 37 2,000 6,104E-04 8,929E-03 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 6,104E-04 8,876E-03 ! mitochondrion organization GO:0007005 159 87 3,000 6,431E-04 9,296E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 6,605E-04 9,492E-03 ! induction of positive chemotaxis GO:0050930 17 9 1,000 7,013E-04 0,01001861 ! carbohydrate homeostasis GO:0033500 59 39 2,000 7,132E-04 0,01013007 GO:0042593|glucose homeostasis, ! positive regulation of protein modification process GO:0031401 156 90 3,000 7,306E-04 0,01031684 ! multicellular organismal metabolic process GO:0044236 64 41 2,000 8,265E-04 0,01160398 ! regulation of developmental growth GO:0048638 16 10 1,000 8,74E-04 0,01220106 ! associative learning GO:0008306 21 10 1,000 8,74E-04 0,01213174 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 8,74E-04 0,0120632 ! positive regulation of heart contraction GO:0045823 17 10 1,000 8,74E-04 0,01199543 ! lung alveolus development GO:0048286 26 10 1,000 8,74E-04 0,01192841 ! phosphagen metabolic process GO:0006599 17 10 1,000 8,74E-04 0,01186214 GO:0006600|creatine metabolic process, ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 1,000 8,74E-04 0,01179661 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 8,74E-04 0,01173179 ! regulation of bone resorption GO:0045124 25 10 1,000 8,74E-04 0,01166768 ! protein heterooligomerization GO:0051291 17 10 1,000 8,74E-04 0,01160427 ! response to nicotine GO:0035094 20 10 1,000 8,74E-04 0,01154155 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 9,506E-04 0,01248517 ! regulation of DNA metabolic process GO:0051052 188 97 3,000 9,67E-04 0,01263302 ! keratinocyte proliferation GO:0043616 19 11 1,000 1,065E-03 0,01384047 ! blood vessel remodeling GO:0001974 30 11 1,000 1,065E-03 0,01376724 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,065E-03 0,01369478 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of catecholamine secretion GO:0050433 20 11 1,000 1,065E-03 0,01362308 ! regulation of intracellular pH GO:0051453 21 11 1,000 1,065E-03 0,01355213 ! substrate-bound cell migration GO:0006929 14 11 1,000 1,065E-03 0,01348191 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 1,065E-03 0,01341241 ! negative regulation of tumor necrosis factor production GO:0032720 16 11 1,000 1,065E-03 0,01334363 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,065E-03 0,01327555 ! regulation of embryonic development GO:0045995 35 11 1,000 1,065E-03 0,01320816 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 1,086E-03 0,01339781 ! response to insulin stimulus GO:0032868 98 47 2,000 1,233E-03 0,01513355 ! positive regulation of blood pressure GO:0045777 18 12 1,000 1,274E-03 0,01556622 ! virus-host interaction GO:0019048 30 12 1,000 1,274E-03 0,01548877 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 1,274E-03 0,0154121 GO:0050927|positive regulation of positive chemotaxis, ! regulation of hormone metabolic process GO:0032350 28 12 1,000 1,274E-03 0,01533617 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,274E-03 0,015261 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,274E-03 0,01518655 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,274E-03 0,01511283 ! embryonic placenta development GO:0001892 21 12 1,000 1,274E-03 0,01503982 ! localization within membrane GO:0051668 26 12 1,000 1,274E-03 0,01496752 ! regulation of JAK-STAT cascade GO:0046425 76 48 2,000 1,311E-03 0,01531994 ! JAK-STAT cascade GO:0007259 82 48 2,000 1,311E-03 0,01524699 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 1,392E-03 0,01611165 ! activation of caspase activity GO:0006919 95 50 2,000 1,476E-03 0,01700357 ! regulation of chemokine production GO:0032642 18 13 1,000 1,502E-03 0,01722296 ! positive regulation of cell growth GO:0030307 24 13 1,000 1,502E-03 0,01714248 ! response to X-ray GO:0010165 28 13 1,000 1,502E-03 0,01706275 ! histone methylation GO:0016571 29 13 1,000 1,502E-03 0,01698375 ! regulation of mRNA stability GO:0043488 32 13 1,000 1,502E-03 0,01690549 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 1,502E-03 0,01682794 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 1,653E-03 0,01843875 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 1,746E-03 0,01939282 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of S phase GO:0033261 26 14 1,000 1,747E-03 0,01930928 ! regulation of heart rate GO:0002027 25 14 1,000 1,747E-03 0,0192223 ! negative regulation of caspase activity GO:0043154 23 14 1,000 1,747E-03 0,0191361 ! regulation of cellular pH GO:0030641 27 14 1,000 1,747E-03 0,01905067 ! response to gamma radiation GO:0010332 30 14 1,000 1,747E-03 0,018966 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 1,747E-03 0,01888208 ! regulation of RNA stability GO:0043487 33 14 1,000 1,747E-03 0,0187989 ! regulation of angiogenesis GO:0045765 125 54 2,000 1,843E-03 0,01974853 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 2,01E-03 0,02143854 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 2,01E-03 0,02134533 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,01E-03 0,02125293 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 2,01E-03 0,02116132 ! muscle maintenance GO:0046716 26 15 1,000 2,01E-03 0,0210705 ! dopamine metabolic process GO:0042417 35 15 1,000 2,01E-03 0,02098045 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 2,01E-03 0,02089118 ! regulation of bone remodeling GO:0046850 143 57 2,000 2,153E-03 0,0222874 ! positive regulation of caspase activity GO:0043280 108 57 2,000 2,153E-03 0,02219336 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 105 57 2,000 2,153E-03 0,02210011 ! aging GO:0007568 112 58 2,000 2,263E-03 0,0231325 ! regulation of tissue remodeling GO:0034103 146 58 2,000 2,263E-03 0,02303611 ! positive regulation of cell size GO:0045793 29 16 1,000 2,29E-03 0,02321297 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 2,29E-03 0,02311705 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! negative regulation of inflammatory response GO:0050728 24 16 1,000 2,29E-03 0,02302191 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 2,29E-03 0,02292756 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 2,29E-03 0,02283398 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,29E-03 0,02274116 ! regulation of endocytosis GO:0030100 104 60 2,000 2,493E-03 0,02466221 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 2,588E-03 0,02549055 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 2,588E-03 0,02538817 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 2,588E-03 0,02528662 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 2,588E-03 0,02518588 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 2,588E-03 0,02508593 ! heart looping GO:0001947 34 18 1,000 2,903E-03 0,02802778 ! neural crest cell migration GO:0001755 41 18 1,000 2,903E-03 0,02791744 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 2,997E-03 0,02870845 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 2,997E-03 0,02859631 ! negative regulation of defense response GO:0031348 27 19 1,000 3,235E-03 0,03074731 ! memory GO:0007613 34 19 1,000 3,235E-03 0,03062814 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 3,235E-03 0,03050988 ! skin development GO:0043588 42 20 1,000 3,583E-03 0,03367063 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 3,583E-03 0,03354162 ! response to alkaloid GO:0043279 38 20 1,000 3,583E-03 0,0334136 ! cellular response to unfolded protein GO:0034620 35 20 1,000 3,583E-03 0,03328655 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 1,000 3,583E-03 0,03316047 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 3,583E-03 0,03303533 ! estrogen receptor signaling pathway GO:0030520 45 20 1,000 3,583E-03 0,03291114 ! negative regulation of T cell activation GO:0050868 41 20 1,000 3,583E-03 0,03278788 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 3,707E-03 0,03379617 ! lipid phosphorylation GO:0046834 43 21 1,000 3,949E-03 0,03586454 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 3,949E-03 0,03573171 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 3,949E-03 0,03559985 ! B cell activation GO:0042113 179 72 2,000 4,179E-03 0,03753635 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 4,331E-03 0,03875924 ! cellular response to starvation GO:0009267 37 22 1,000 4,331E-03 0,03861778 ! apoptotic nuclear changes GO:0030262 34 22 1,000 4,331E-03 0,03847736 ! cell aging GO:0007569 48 22 1,000 4,331E-03 0,03833795 ! positive regulation of locomotion GO:0040017 44 22 1,000 4,331E-03 0,03819954 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of B cell activation GO:0050871 42 22 1,000 4,331E-03 0,03806213 ! regulation of transcription factor activity GO:0051090 137 75 2,000 4,686E-03 0,04103071 GO:0090046|regulation of transcription regulator activity, ! positive regulation of DNA replication GO:0045740 44 23 1,000 4,73E-03 0,0412683 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 4,73E-03 0,04112144 ! regulation of chemotaxis GO:0050920 45 23 1,000 4,73E-03 0,04097562 ! response to ethanol GO:0045471 47 23 1,000 4,73E-03 0,04083083 ! vesicle targeting GO:0006903 49 23 1,000 4,73E-03 0,04068706 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 4,73E-03 0,0405443 ! regulation of interleukin-6 production GO:0032675 31 23 1,000 4,73E-03 0,04040253 ! negative regulation of cytokine production GO:0001818 41 23 1,000 4,73E-03 0,04026176 ! regulation of vesicle-mediated transport GO:0060627 136 77 2,000 5,043E-03 0,0427808 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 5,145E-03 0,04349046 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 5,145E-03 0,04334049 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 5,145E-03 0,04319155 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 5,145E-03 0,04304364 ! sex determination GO:0007530 48 24 1,000 5,145E-03 0,04289673 ! regulation of tumor necrosis factor production GO:0032680 37 24 1,000 5,145E-03 0,04275082 ! regulation of amine transport GO:0051952 41 24 1,000 5,145E-03 0,0426059 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 5,417E-03 0,04470706 ! protein oligomerization GO:0051259 149 79 2,000 5,417E-03 0,04455654 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 5,576E-03 0,04571058 ! regulation of transmembrane transport GO:0034762 39 25 1,000 5,576E-03 0,04555771 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 5,576E-03 0,04540585 ! vasculogenesis GO:0001570 49 25 1,000 5,576E-03 0,045255 ! negative regulation of DNA replication GO:0008156 45 25 1,000 5,576E-03 0,04510515 ! regulation of behavior GO:0050795 48 25 1,000 5,576E-03 0,04495628 ! interaction with host GO:0051701 66 25 1,000 5,576E-03 0,0448084 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 6,023E-03 0,04824195 ! protein amino acid alkylation GO:0008213 59 26 1,000 6,023E-03 0,04808429 GO:0006479|protein amino acid methylation, ! neural crest cell development GO:0014032 59 26 1,000 6,023E-03 0,04792767 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 83 26 1,000 6,023E-03 0,04777206 GO:0050768|negative regulation of neurogenesis, ! response to estradiol stimulus GO:0032355 43 26 1,000 6,023E-03 0,04761746 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 6,023E-03 0,04746385 ! T cell activation GO:0042110 189 84 2,000 6,422E-03 0,0504453 ! regulation of ligase activity GO:0051340 147 84 2,000 6,422E-03 0,05028361 ! mitochondrial membrane organization GO:0007006 60 27 1,000 6,486E-03 0,05062139 ! response to starvation GO:0042594 47 27 1,000 6,486E-03 0,05046017 ! cellular response to oxidative stress GO:0034599 43 27 1,000 6,486E-03 0,05029998 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 6,486E-03 0,05014081 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 6,964E-03 0,05367033 ! fat cell differentiation GO:0045444 57 28 1,000 6,964E-03 0,05350155 ! sperm motility GO:0030317 37 28 1,000 6,964E-03 0,05333384 ! base-excision repair GO:0006284 41 28 1,000 6,964E-03 0,05316717 ! regulation of systemic arterial blood pressure GO:0003073 55 28 1,000 6,964E-03 0,05300154 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 7,458E-03 0,05658519 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 7,458E-03 0,05641 ! catechol metabolic process GO:0009712 55 29 1,000 7,458E-03 0,0562359 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to organic cyclic substance GO:0014070 58 29 1,000 7,458E-03 0,05606286 ! somitogenesis GO:0001756 52 29 1,000 7,458E-03 0,05589089 ! regulation of DNA binding GO:0051101 167 89 2,000 7,531E-03 0,05626211 ! tube morphogenesis GO:0035239 194 89 2,000 7,531E-03 0,05609058 ! regulation of cell cycle process GO:0010564 161 90 2,000 7,765E-03 0,0576613 ! phenol metabolic process GO:0018958 56 30 1,000 7,968E-03 0,05898468 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 7,968E-03 0,05880648 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 7,968E-03 0,05862935 ! neurotransmitter secretion GO:0007269 55 30 1,000 7,968E-03 0,05845329 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 7,968E-03 0,05827828 GO:0043433|negative regulation of transcription factor activity, ! regulation of cell adhesion GO:0030155 241 92 2,000 8,247E-03 0,06014225 ! ovulation cycle process GO:0022602 55 31 1,000 8,492E-03 0,06174608 ! iron ion homeostasis GO:0055072 60 31 1,000 8,492E-03 0,06156286 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 8,492E-03 0,06138072 ! female pregnancy GO:0007565 166 94 2,000 8,746E-03 0,063029 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 9,002E-03 0,06468325 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 9,032E-03 0,0647076 ! collagen metabolic process GO:0032963 49 32 1,000 9,032E-03 0,0645184 ! ovulation cycle GO:0042698 57 32 1,000 9,032E-03 0,0643303 ! regulation of pH GO:0006885 56 33 1,000 9,587E-03 0,06808261 ! negative regulation of response to external stimulus GO:0032102 50 33 1,000 9,587E-03 0,06788527 ! response to ionizing radiation GO:0010212 74 33 1,000 9,587E-03 0,06768907 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 9,587E-03 0,067494 ! establishment of vesicle localization GO:0051650 67 33 1,000 9,587E-03 0,06730005 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01015625 0,07109373 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 0,01074041 0,07496808 ! positive regulation of endocytosis GO:0045807 56 35 1,000 0,01074041 0,0747545 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 0,01074041 0,07454213 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01074041 0,07433096 ! biogenic amine biosynthetic process GO:0042401 65 35 1,000 0,01074041 0,07412099 ! placenta development GO:0001890 53 35 1,000 0,01074041 0,07391219 ! vesicle localization GO:0051648 70 35 1,000 0,01074041 0,07370458 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,0113391 0,07759503 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,0113391 0,07737828 ! positive regulation of cell development GO:0010720 85 36 1,000 0,0113391 0,07716274 ! embryonic organ development GO:0048568 67 36 1,000 0,0113391 0,0769484 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01195217 0,08088409 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01195217 0,08066066 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01195217 0,08043845 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01257949 0,08442771 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,01257949 0,0841964 ! regulation of protein stability GO:0031647 77 38 1,000 0,01257949 0,08396636 ! negative regulation of binding GO:0051100 71 39 1,000 0,01322091 0,0880073 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01322091 0,08776815 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 82 40 1,000 0,0138763 0,09186936 ! nucleus organization GO:0006997 73 40 1,000 0,0138763 0,09162106 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,0138763 0,09137411 ! cellular amide metabolic process GO:0043603 73 41 1,000 0,01454552 0,09552339 ! gliogenesis GO:0042063 91 41 1,000 0,01454552 0,09526729 ! mesenchymal cell development GO:0014031 94 41 1,000 0,01454552 0,09501257 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01454552 0,0947592 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,01522844 0,09894434 ! T cell differentiation GO:0030217 93 42 1,000 0,01522844 0,09868188 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,01522844 0,09842082 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01592492 0,10265059 GO:0090047|positive regulation of transcription regulator activity, ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,01592492 0,10238046 ! segmentation GO:0035282 78 43 1,000 0,01592492 0,10211174 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,01663483 0,10638452 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 0,01663483 0,10610675 ! double-strand break repair GO:0006302 85 44 1,000 0,01663483 0,10583043 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,01735804 0,11014463 ! biopolymer methylation GO:0043414 91 45 1,000 0,01735804 0,10985928 ! B cell differentiation GO:0030183 124 45 1,000 0,01735804 0,10957541 ! mitochondrial transport GO:0006839 94 48 1,000 0,01960613 0,12344787 ! cellular component disassembly GO:0022411 89 48 1,000 0,01960613 0,12313053 ! endosome transport GO:0016197 127 48 1,000 0,01960613 0,12281481 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01960613 0,1225007 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,01960613 0,1221882 ! regulation of inflammatory response GO:0050727 84 48 1,000 0,01960613 0,12187729 ! methylation GO:0032259 97 48 1,000 0,01960613 0,12156795 ! response to calcium ion GO:0051592 94 49 1,000 0,02038122 0,12605396 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,02038122 0,12573564 ! regulation of action potential GO:0001508 102 50 1,000 0,02116895 0,13026639 ! regulation of ossification GO:0030278 123 50 1,000 0,02116895 0,12993908 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,02116895 0,12961342 ! positive regulation of cytokine production GO:0001819 94 50 1,000 0,02116895 0,12928939 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,02196921 0,13384235 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02216867 0,13472153 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02216867 0,13438723 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02216867 0,13405459 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02216867 0,13372359 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02216867 0,13339422 ! neuron fate determination GO:0048664 7 5 0,000 0,02216867 0,13306647 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02216867 0,13274033 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02216867 0,13241578 ! polyol transport GO:0015791 12 5 0,000 0,02216867 0,13209281 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02216867 0,13177142 ! response to superoxide GO:0000303 10 5 0,000 0,02216867 0,13145159 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02216867 0,1311333 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02216867 0,13081655 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02216867 0,13050133 ! female meiosis GO:0007143 10 5 0,000 0,02216867 0,13018763 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02216867 0,12987543 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02216867 0,12956472 ! hypothalamus development GO:0021854 9 5 0,000 0,02216867 0,1292555 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02216867 0,12894775 ! cobalt ion transport GO:0006824 11 5 0,000 0,02216867 0,12864146 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02216867 0,12833662 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02216867 0,12803322 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02216867 0,12773126 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02216867 0,12743071 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02216867 0,12713158 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02216867 0,12683385 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02216867 0,12653751 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02216867 0,12624255 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02216867 0,12594896 ! transposition GO:0032196 9 5 0,000 0,02216867 0,12565674 ! negative chemotaxis GO:0050919 16 5 0,000 0,02216867 0,12536586 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02216867 0,12507634 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02216867 0,12478814 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02216867 0,12450127 ! behavioral response to pain GO:0048266 10 5 0,000 0,02216867 0,12421572 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02216867 0,12393147 ! Notch receptor processing GO:0007220 11 5 0,000 0,02216867 0,12364852 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02216867 0,12336686 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02216867 0,12308648 ! micturition GO:0060073 9 5 0,000 0,02216867 0,12280738 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02216867 0,12252953 ! copulation GO:0007620 9 5 0,000 0,02216867 0,12225294 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02216867 0,1219776 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02216867 0,12170349 ! bioluminescence GO:0008218 9 5 0,000 0,02216867 0,12143061 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02216867 0,12115896 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02216867 0,12088851 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02216867 0,12061927 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02216867 0,12035123 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02216867 0,12008438 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02216867 0,1198187 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02216867 0,1195542 ! grooming behavior GO:0007625 6 5 0,000 0,02216867 0,11929087 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02216867 0,11902869 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02216867 0,11876766 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02216867 0,11850777 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02216867 0,11824902 ! response to protozoan GO:0001562 13 5 0,000 0,02216867 0,1179914 ! lymph vessel development GO:0001945 10 5 0,000 0,02216867 0,1177349 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02216867 0,11747951 ! endochondral ossification GO:0001958 17 5 0,000 0,02216867 0,11722522 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02216867 0,11697204 ! single strand break repair GO:0000012 8 5 0,000 0,02216867 0,11671994 ! parathyroid gland development GO:0060017 14 5 0,000 0,02216867 0,11646893 ! anagen GO:0042640 7 5 0,000 0,02216867 0,116219 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02216867 0,11597014 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02216867 0,11572234 ! cytokine secretion GO:0050663 15 5 0,000 0,02216867 0,11547559 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02216867 0,1152299 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02216867 0,11498525 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02216867 0,11474164 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02216867 0,11449906 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02216867 0,1142575 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02216867 0,11401695 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02216867 0,11377742 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02216867 0,1135389 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02216867 0,11330137 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02216867 0,11306483 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02216867 0,11282928 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02216867 0,11259471 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02216867 0,11236111 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02216867 0,11212847 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02216867 0,1118968 ! microvillus organization GO:0032528 8 5 0,000 0,02216867 0,11166609 GO:0030033|microvillus assembly, ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02216867 0,11143632 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02216867 0,1112075 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02216867 0,11097962 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02216867 0,11075266 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02216867 0,11052664 ! polyol catabolic process GO:0046174 9 5 0,000 0,02216867 0,11030153 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02216867 0,11007734 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02216867 0,10985406 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02216867 0,10963169 ! muscle cell migration GO:0014812 8 5 0,000 0,02216867 0,10941021 ! mitochondrial fission GO:0000266 8 5 0,000 0,02216867 0,10918962 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02216867 0,10896993 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02216867 0,10875111 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02216867 0,10853317 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02216867 0,10831611 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02216867 0,10809991 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02216867 0,10788457 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02216867 0,10767009 ! monocyte activation GO:0042117 10 5 0,000 0,02216867 0,10745645 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02216867 0,10724367 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02216867 0,10703173 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02216867 0,10682062 ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02216867 0,10661034 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02216867 0,10640089 ! forebrain neuron development GO:0021884 13 5 0,000 0,02216867 0,10619226 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02216867 0,10598445 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02216867 0,10577745 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02216867 0,10557125 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02216867 0,10536586 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02216867 0,10516127 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02216867 0,10495747 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02216867 0,10475445 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02216867 0,10455223 ! lipid glycosylation GO:0030259 7 5 0,000 0,02216867 0,10435078 ! nucleobase transport GO:0015851 6 5 0,000 0,02216867 0,1041501 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02216867 0,1039502 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02216867 0,10375106 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02216867 0,10355268 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02216867 0,10335506 ! basic amino acid transport GO:0015802 12 5 0,000 0,02216867 0,1031582 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02216867 0,10296208 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02216867 0,1027667 ! actin nucleation GO:0045010 11 5 0,000 0,02216867 0,10257207 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02216867 0,10237817 ! depurination GO:0045007 5 5 0,000 0,02216867 0,10218501 ! depyrimidination GO:0045008 10 5 0,000 0,02216867 0,10199257 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02216867 0,10180085 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02216867 0,10160986 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02216867 0,10141958 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02216867 0,10123001 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02216867 0,10104114 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02216867 0,10085299 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02216867 0,10066553 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02216867 0,10047876 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02216867 0,10029269 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02216867 0,10010731 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02216867 0,09992261 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02216867 0,09973859 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02216867 0,09955524 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02216867 0,09937257 ! response to arsenic GO:0046685 11 5 0,000 0,02216867 0,09919057 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02216867 0,09900924 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02216867 0,09882856 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02216867 0,09864855 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02216867 0,09846919 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02216867 0,09829048 ! response to mercury ion GO:0046689 8 5 0,000 0,02216867 0,09811242 ! response to cadmium ion GO:0046686 7 5 0,000 0,02216867 0,097935 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02216867 0,09775822 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02216867 0,09758208 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02216867 0,09740657 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02216867 0,09723169 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02216867 0,09705744 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02216867 0,09688382 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02216867 0,09671081 ! decidualization GO:0046697 11 5 0,000 0,02216867 0,09653842 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02216867 0,09636664 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02216867 0,09619548 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02216867 0,09602492 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02216867 0,09585496 ! embryonic cleavage GO:0040016 6 5 0,000 0,02216867 0,09568561 ! peroxisome fission GO:0016559 5 5 0,000 0,02216867 0,09551685 ! histone demethylation GO:0016577 13 5 0,000 0,02216867 0,09534869 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02216867 0,09518111 ! mitotic recombination GO:0006312 9 5 0,000 0,02216867 0,09501413 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02216867 0,09484773 ! metaphase plate congression GO:0051310 7 5 0,000 0,02216867 0,09468191 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02216867 0,09451667 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02216867 0,09435201 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02216867 0,09418792 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02216867 0,0940244 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02216867 0,09386144 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02216867 0,09369905 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02216867 0,09353722 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02216867 0,09337595 ! B cell homeostasis GO:0001782 13 5 0,000 0,02216867 0,09321524 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02216867 0,09305507 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02216867 0,09289546 ! metaphase GO:0051323 11 5 0,000 0,02216867 0,09273639 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02216867 0,09257787 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02216867 0,09241989 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02216867 0,09226244 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02216867 0,09210553 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02216867 0,09194916 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02216867 0,09179331 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02216867 0,09163799 ! response to redox state GO:0051775 6 5 0,000 0,02216867 0,0914832 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02216867 0,09132893 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02216867 0,09117517 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02216867 0,09102194 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02216867 0,09086922 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02216867 0,09071701 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02216867 0,09056531 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02216867 0,09041411 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02216867 0,09026342 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02216867 0,09011323 ! striatum development GO:0021756 14 5 0,000 0,02216867 0,08996354 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02216867 0,08981435 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02216867 0,08966565 ! glial cell migration GO:0008347 10 5 0,000 0,02216867 0,08951744 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02216867 0,08936972 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02216867 0,08922249 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02216867 0,08907575 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02216867 0,08892948 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02216867 0,08878369 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02216867 0,08863838 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02216867 0,08849355 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02216867 0,08834919 ! neuroprotection GO:0043526 8 5 0,000 0,02216867 0,0882053 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02216867 0,08806188 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02216867 0,08791892 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02216867 0,08777642 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02216867 0,08763439 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02216867 0,08749282 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02216867 0,0873517 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02216867 0,08721104 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02216867 0,08707082 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02216867 0,08693106 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02216867 0,08679175 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02216867 0,08665289 ! spindle assembly GO:0051225 6 5 0,000 0,02216867 0,08651446 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02216867 0,08637648 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02216867 0,08623894 ! protein palmitoylation GO:0018345 12 5 0,000 0,02216867 0,08610183 ! drug metabolic process GO:0017144 7 5 0,000 0,02216867 0,08596516 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02216867 0,08582893 ! organ regeneration GO:0031100 7 5 0,000 0,02216867 0,08569312 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02216867 0,08555775 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02216867 0,0854228 ! positive regulation of binding GO:0051099 88 52 1,000 0,02278186 0,08764739 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,02278186 0,08750958 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,02278186 0,0873722 ! chromatin remodeling GO:0006338 122 53 1,000 0,02360678 0,090394 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 0,02360678 0,09025254 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,02360678 0,09011152 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,02360678 0,08997094 ! cartilage development GO:0051216 99 53 1,000 0,02360678 0,0898308 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,02444385 0,09287142 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,02444385 0,09272721 ! regulation of cell shape GO:0008360 142 54 1,000 0,02444385 0,09258345 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,02529293 0,09565115 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,02529293 0,09550331 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,02529293 0,09535593 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,02615392 0,09844996 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02654344 0,09976251 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02654344 0,09960927 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02654344 0,09945649 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02654344 0,09930418 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02654344 0,09915234 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02654344 0,09900097 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02654344 0,09885005 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02654344 0,09869959 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02654344 0,09854959 ! response to oxygen radical GO:0000305 11 6 0,000 0,02654344 0,09840005 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02654344 0,09825096 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02654344 0,09810232 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02654344 0,09795413 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02654344 0,09780638 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02654344 0,09765908 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02654344 0,09751223 ! forebrain regionalization GO:0021871 9 6 0,000 0,02654344 0,09736581 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02654344 0,09721984 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02654344 0,0970743 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02654344 0,0969292 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02654344 0,09678453 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02654344 0,09664029 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02654344 0,09649648 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02654344 0,09635309 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02654344 0,09621014 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02654344 0,0960676 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02654344 0,09592549 ! malate metabolic process GO:0006108 13 6 0,000 0,02654344 0,0957838 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02654344 0,09564253 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02654344 0,09550167 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02654344 0,09536122 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02654344 0,09522119 ! protein refolding GO:0042026 15 6 0,000 0,02654344 0,09508157 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02654344 0,09494236 ! opsonization GO:0008228 8 6 0,000 0,02654344 0,09480356 ! mating behavior GO:0007617 7 6 0,000 0,02654344 0,09466516 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02654344 0,09452716 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02654344 0,09438957 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02654344 0,09425237 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02654344 0,09411558 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02654344 0,09397918 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02654344 0,09384317 ! toxin metabolic process GO:0009404 11 6 0,000 0,02654344 0,09370756 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02654344 0,09357234 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02654344 0,09343751 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02654344 0,09330307 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02654344 0,09316901 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02654344 0,09303534 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02654344 0,09290205 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02654344 0,09276914 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02654344 0,09263662 ! thymic T cell selection GO:0045061 16 6 0,000 0,02654344 0,09250447 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02654344 0,0923727 ! protein lipoylation GO:0009249 10 6 0,000 0,02654344 0,0922413 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02654344 0,09211027 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02654344 0,09197962 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02654344 0,09184934 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02654344 0,09171942 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02654344 0,09158988 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02654344 0,09146069 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02654344 0,09133188 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02654344 0,09120342 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02654344 0,09107533 ! hyperosmotic response GO:0006972 10 6 0,000 0,02654344 0,09094759 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02654344 0,09082021 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02654344 0,09069319 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02654344 0,09056653 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02654344 0,09044021 ! urea metabolic process GO:0019627 7 6 0,000 0,02654344 0,09031425 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02654344 0,09018864 ! neutrophil activation GO:0042119 7 6 0,000 0,02654344 0,09006338 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02654344 0,08993846 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02654344 0,08981389 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02654344 0,08968967 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02654344 0,08956579 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02654344 0,08944225 ! neuron apoptosis GO:0051402 15 6 0,000 0,02654344 0,08931905 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02654344 0,08919619 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02654344 0,08907367 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02654344 0,08895148 ! carnitine transport GO:0015879 10 6 0,000 0,02654344 0,08882963 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02654344 0,08870812 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02654344 0,08858693 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02654344 0,08846607 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02654344 0,08834555 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02654344 0,08822535 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02654344 0,08810548 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02654344 0,08798593 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02654344 0,08786671 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02654344 0,08774781 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02654344 0,08762923 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02654344 0,08751097 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02654344 0,08739304 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02654344 0,08727541 ! response to UV-C GO:0010225 14 6 0,000 0,02654344 0,08715811 ! astrocyte development GO:0014002 16 6 0,000 0,02654344 0,08704112 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02654344 0,08692444 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02654344 0,08680808 ! interaction with symbiont GO:0051702 14 6 0,000 0,02654344 0,08669202 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02654344 0,08657628 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02654344 0,08646084 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02654344 0,08634572 ! response to copper ion GO:0046688 10 6 0,000 0,02654344 0,08623089 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02654344 0,08611638 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02654344 0,08600216 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02654344 0,08588825 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02654344 0,08577465 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02654344 0,08566134 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02654344 0,08554833 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02654344 0,08543562 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02654344 0,0853232 ! hair follicle maturation GO:0048820 8 6 0,000 0,02654344 0,08521108 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02654344 0,08509925 ! Schwann cell development GO:0014044 15 6 0,000 0,02654344 0,08498772 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02654344 0,08487648 ! response to pheromone GO:0019236 6 6 0,000 0,02654344 0,08476553 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02654344 0,08465487 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02654344 0,0845445 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02654344 0,08443442 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02654344 0,08432462 ! subpallium development GO:0021544 15 6 0,000 0,02654344 0,08421511 ! neural tube patterning GO:0021532 8 6 0,000 0,02654344 0,08410588 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02654344 0,08399693 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02654344 0,08388827 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02654344 0,08377989 ! G2 phase GO:0051319 16 6 0,000 0,02654344 0,08367178 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02654344 0,08356396 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02654344 0,08345641 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02654344 0,08334914 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02654344 0,08324215 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02654344 0,08313543 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02654344 0,08302898 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02654344 0,0829228 ! receptor internalization GO:0031623 11 6 0,000 0,02654344 0,0828169 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02654344 0,08271127 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02654344 0,0826059 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02654344 0,0825008 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02654344 0,08239597 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02654344 0,08229141 ! protein deubiquitination GO:0016579 16 6 0,000 0,02654344 0,08218711 ! protein destabilization GO:0031648 9 6 0,000 0,02654344 0,08208308 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02654344 0,08197931 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02654344 0,0818758 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02654344 0,08177255 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02654344 0,08166956 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02654344 0,08156683 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02654344 0,08146436 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02654344 0,08136215 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02654344 0,08126019 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02654344 0,08115849 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02654344 0,08105704 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02654344 0,08095585 ! neural plate development GO:0001840 9 6 0,000 0,02654344 0,0808549 ! catecholamine transport GO:0051937 9 6 0,000 0,02654344 0,08075421 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02654344 0,08065377 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02654344 0,08055358 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02654344 0,08045364 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02654344 0,08035394 ! maternal placenta development GO:0001893 12 6 0,000 0,02654344 0,0802545 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02654344 0,08015529 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02654344 0,08005634 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02654344 0,07995762 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02654344 0,07985915 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02654344 0,07976093 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02654344 0,07966294 GO:0055081|anion homeostasis, ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,02702668 0,08101371 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,02702668 0,08091443 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 1,000 0,02791109 0,08345998 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,02791109 0,08335795 ! establishment of organelle localization GO:0051656 122 59 1,000 0,02880704 0,0859287 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,02971441 0,08852719 ! lipid modification GO:0030258 112 60 1,000 0,02971441 0,08841936 ! DNA catabolic process GO:0006308 94 60 1,000 0,02971441 0,0883118 ! adult behavior GO:0030534 104 60 1,000 0,02971441 0,08820449 ! regulation of heart contraction GO:0008016 123 61 1,000 0,03063307 0,0908211 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 0,03063307 0,09071101 ! tRNA transcription GO:0009304 17 7 0,000 0,03089877 0,09138704 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03089877 0,09127654 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03089877 0,0911663 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03089877 0,09105633 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03089877 0,09094662 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03089877 0,09083718 ! sleep GO:0030431 16 7 0,000 0,03089877 0,090728 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03089877 0,09061908 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03089877 0,09051043 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03089877 0,09040203 ! prostate gland development GO:0030850 14 7 0,000 0,03089877 0,09029389 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03089877 0,09018602 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03089877 0,09007839 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03089877 0,08997103 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03089877 0,08986392 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03089877 0,08975707 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03089877 0,08965047 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03089877 0,08954412 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03089877 0,08943803 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03089877 0,08933218 ! glycolipid transport GO:0046836 11 7 0,000 0,03089877 0,08922659 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03089877 0,08912125 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03089877 0,08901615 ! neuron adhesion GO:0007158 14 7 0,000 0,03089877 0,0889113 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03089877 0,0888067 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03089877 0,08870234 ! pericardium development GO:0060039 16 7 0,000 0,03089877 0,08859823 ! fibril organization GO:0043206 17 7 0,000 0,03089877 0,08849437 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03089877 0,08839074 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03089877 0,08828736 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03089877 0,08818422 ! lipoprotein transport GO:0042953 14 7 0,000 0,03089877 0,08808132 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03089877 0,08797867 ! rhythmic behavior GO:0007622 17 7 0,000 0,03089877 0,08787625 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03089877 0,08777406 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03089877 0,08767212 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03089877 0,08757041 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03089877 0,08746894 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03089877 0,0873677 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03089877 0,0872667 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03089877 0,08716593 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03089877 0,08706539 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03089877 0,08696509 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03089877 0,08686501 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03089877 0,08676517 GO:0045911|positive regulation of DNA recombination, ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03089877 0,08666555 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03089877 0,08656616 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03089877 0,086467 ! spinal cord patterning GO:0021511 14 7 0,000 0,03089877 0,08636807 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03089877 0,08626937 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03089877 0,08617088 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03089877 0,08607263 ! adrenal gland development GO:0030325 17 7 0,000 0,03089877 0,0859746 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03089877 0,08587679 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03089877 0,0857792 ! ovulation GO:0030728 10 7 0,000 0,03089877 0,08568183 ! adenohypophysis development GO:0021984 11 7 0,000 0,03089877 0,08558469 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03089877 0,08548776 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03089877 0,08539106 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03089877 0,08529457 ! microtubule nucleation GO:0007020 21 7 0,000 0,03089877 0,0851983 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03089877 0,08510225 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03089877 0,08500641 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03089877 0,08491079 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03089877 0,08481539 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03089877 0,0847202 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03089877 0,08462522 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03089877 0,08453045 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03089877 0,0844359 ! galactose metabolic process GO:0006012 13 7 0,000 0,03089877 0,08434156 ! vesicle fusion GO:0006906 20 7 0,000 0,03089877 0,08424743 ! response to dietary excess GO:0002021 8 7 0,000 0,03089877 0,08415351 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03089877 0,08405979 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03089877 0,08396629 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03089877 0,08387299 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03089877 0,08377991 ! organ growth GO:0035265 15 7 0,000 0,03089877 0,08368702 ! nucleoside transport GO:0015858 11 7 0,000 0,03089877 0,08359435 ! nucleoside salvage GO:0043174 11 7 0,000 0,03089877 0,08350187 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03089877 0,08340961 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03089877 0,08331754 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03089877 0,08322568 ! parturition GO:0007567 16 7 0,000 0,03089877 0,08313403 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03089877 0,08304257 ! rRNA modification GO:0000154 14 7 0,000 0,03089877 0,08295131 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03089877 0,08286026 ! spindle checkpoint GO:0031577 16 7 0,000 0,03089877 0,0827694 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03089877 0,08267875 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03089877 0,08258829 ! monocyte differentiation GO:0030224 16 7 0,000 0,03089877 0,08249803 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03089877 0,08240796 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03089877 0,0823181 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03089877 0,08222843 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03089877 0,08213895 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03089877 0,08204967 ! fibrinolysis GO:0042730 11 7 0,000 0,03089877 0,08196058 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03089877 0,08187169 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03089877 0,08178298 ! eating behavior GO:0042755 8 7 0,000 0,03089877 0,08169447 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03089877 0,08160616 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03089877 0,08151803 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03089877 0,08143009 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03089877 0,08134234 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03089877 0,08125478 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03089877 0,08116741 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03089877 0,08108023 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03089877 0,08099323 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03089877 0,08090643 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03089877 0,0808198 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03089877 0,08073336 ! histone ubiquitination GO:0016574 9 7 0,000 0,03089877 0,08064711 ! regulation of meiosis GO:0040020 12 7 0,000 0,03089877 0,08056104 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03089877 0,08047515 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03089877 0,08038945 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03089877 0,08030393 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03089877 0,08021859 ! transcription termination GO:0006353 14 7 0,000 0,03089877 0,08013343 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03089877 0,08004846 ! anaphase GO:0051322 18 7 0,000 0,03089877 0,07996366 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03089877 0,07987904 ! axonal fasciculation GO:0007413 19 7 0,000 0,03089877 0,0797946 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03089877 0,07971034 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03089877 0,07962626 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03089877 0,07954235 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03089877 0,07945863 ! diuresis GO:0030146 12 7 0,000 0,03089877 0,07937507 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03089877 0,0792917 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03089877 0,07920849 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03089877 0,07912547 ! antibiotic transport GO:0042891 9 7 0,000 0,03089877 0,07904261 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03089877 0,07895993 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03089877 0,07887742 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03089877 0,07879509 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03089877 0,07871292 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03089877 0,07863093 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03089877 0,07854911 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03089877 0,07846746 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03089877 0,07838598 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03089877 0,07830466 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03089877 0,07822352 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03089877 0,07814254 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03089877 0,07806173 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03089877 0,07798109 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03089877 0,07790061 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03089877 0,0778203 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03089877 0,07774016 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03089877 0,07766018 ! muscle adaptation GO:0043500 13 7 0,000 0,03089877 0,07758036 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03089877 0,07750071 ! retina homeostasis GO:0001895 12 7 0,000 0,03089877 0,07742123 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03089877 0,0773419 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03089877 0,07726274 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03089877 0,07718374 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03089877 0,0771049 ! viral reproductive process GO:0022415 132 62 1,000 0,03156291 0,07868182 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,03441833 0,08571252 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03523473 0,08765626 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03523473 0,08756709 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03523473 0,0874781 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03523473 0,08738929 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03523473 0,08730066 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03523473 0,08721221 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03523473 0,08712394 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03523473 0,08703585 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03523473 0,08694793 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03523473 0,08686019 ! meiotic prophase I GO:0007128 14 8 0,000 0,03523473 0,08677263 ! response to zinc ion GO:0010043 12 8 0,000 0,03523473 0,08668525 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,03523473 0,08659804 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03523473 0,08651101 ! oligopeptide transport GO:0006857 16 8 0,000 0,03523473 0,08642415 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03523473 0,08633746 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03523473 0,08625095 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03523473 0,08616462 ! signal peptide processing GO:0006465 12 8 0,000 0,03523473 0,08607845 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03523473 0,08599246 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03523473 0,08590664 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03523473 0,08582099 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03523473 0,08573551 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03523473 0,0856502 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03523473 0,08556506 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03523473 0,08548009 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03523473 0,08539529 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03523473 0,08531065 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03523473 0,08522619 ! reflex GO:0060004 17 8 0,000 0,03523473 0,08514189 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03523473 0,08505776 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03523473 0,08497379 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03523473 0,08488999 ! pigment granule organization GO:0048753 17 8 0,000 0,03523473 0,08480636 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03523473 0,08472288 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03523473 0,08463958 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03523473 0,08455644 ! histidine catabolic process GO:0006548 10 8 0,000 0,03523473 0,08447346 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03523473 0,08439064 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03523473 0,08430798 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03523473 0,08422549 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03523473 0,08414316 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03523473 0,08406099 ! melanin metabolic process GO:0006582 17 8 0,000 0,03523473 0,08397898 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03523473 0,08389713 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03523473 0,08381543 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03523473 0,0837339 ! macrophage activation GO:0042116 13 8 0,000 0,03523473 0,08365253 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03523473 0,08357131 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03523473 0,08349025 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03523473 0,08340935 ! purine salvage GO:0043101 12 8 0,000 0,03523473 0,08332861 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03523473 0,08324802 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03523473 0,08316759 ! osteoblast development GO:0002076 17 8 0,000 0,03523473 0,08308731 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03523473 0,08300719 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03523473 0,08292722 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03523473 0,0828474 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03523473 0,08276774 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03523473 0,08268823 ! response to UV-B GO:0010224 17 8 0,000 0,03523473 0,08260888 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03523473 0,08252967 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03523473 0,08245062 ! intermediate filament organization GO:0045109 12 8 0,000 0,03523473 0,08237172 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03523473 0,08229297 ! cellular extravasation GO:0045123 13 8 0,000 0,03523473 0,08221438 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03523473 0,08213593 ! response to antibiotic GO:0046677 11 8 0,000 0,03523473 0,08205763 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03523473 0,08197948 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03523473 0,08190148 ! DNA topological change GO:0006265 12 8 0,000 0,03523473 0,08182362 ! response to tropane GO:0014073 15 8 0,000 0,03523473 0,08174592 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03523473 0,08166836 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03523473 0,08159095 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03523473 0,08151368 ! mast cell activation GO:0045576 14 8 0,000 0,03523473 0,08143657 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03523473 0,08135959 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03523473 0,08128277 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03523473 0,08120609 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03523473 0,08112955 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03523473 0,08105316 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03523473 0,08097691 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03523473 0,0809008 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03523473 0,08082484 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03523473 0,08074902 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03523473 0,08067334 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03523473 0,0805978 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03523473 0,0805224 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03523473 0,08044715 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03523473 0,08037204 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03523473 0,08029706 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03523473 0,08022223 ! hormone catabolic process GO:0042447 17 8 0,000 0,03523473 0,08014753 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03523473 0,08007298 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03523473 0,07999856 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03523473 0,07992428 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03523473 0,07985014 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03523473 0,07977614 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03523473 0,07970227 ! adult feeding behavior GO:0008343 10 8 0,000 0,03523473 0,07962854 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03523473 0,07955495 ! ATP catabolic process GO:0006200 11 8 0,000 0,03523473 0,07948149 ! blastocyst growth GO:0001832 19 8 0,000 0,03523473 0,07940816 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03523473 0,07933498 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03523473 0,07926193 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03523473 0,07918901 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03523473 0,07911622 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03523473 0,07904357 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03523473 0,07897106 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03523473 0,07889867 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03523473 0,07882642 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03523473 0,0787543 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03523473 0,07868231 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03523473 0,07861046 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03523473 0,07853873 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03523473 0,07846714 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03523473 0,07839567 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03523473 0,07832434 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03523473 0,07825314 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03523473 0,07818206 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03523473 0,07811112 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,03637571 0,08056742 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,03737019 0,08269509 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 142 68 1,000 0,03737019 0,08262026 ! regulation of lipase activity GO:0060191 137 68 1,000 0,03737019 0,08254556 ! adaptive immune response GO:0002250 126 68 1,000 0,03737019 0,08247099 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,03737019 0,08239656 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,03837505 0,08453584 ! axon extension GO:0048675 16 9 0,000 0,03955142 0,08704875 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03955142 0,0869704 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03955142 0,08689218 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03955142 0,08681411 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03955142 0,08673618 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03955142 0,08665839 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03955142 0,08658074 ! reproductive behavior GO:0019098 22 9 0,000 0,03955142 0,08650323 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03955142 0,08642586 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03955142 0,08634862 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03955142 0,08627153 ! UTP metabolic process GO:0046051 10 9 0,000 0,03955142 0,08619457 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03955142 0,08611774 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03955142 0,08604106 ! artery development GO:0060840 25 9 0,000 0,03955142 0,08596451 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03955142 0,0858881 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03955142 0,08581182 ! equilibrioception GO:0050957 20 9 0,000 0,03955142 0,08573568 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03955142 0,08565967 ! chemosensory behavior GO:0007635 21 9 0,000 0,03955142 0,0855838 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03955142 0,08550806 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03955142 0,08543246 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03955142 0,08535699 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03955142 0,08528165 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03955142 0,08520645 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03955142 0,08513137 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03955142 0,08505643 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03955142 0,08498163 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03955142 0,08490695 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03955142 0,08483241 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03955142 0,08475799 ! protein targeting to ER GO:0045047 25 9 0,000 0,03955142 0,08468371 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03955142 0,08460955 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,03955142 0,08453553 ! T cell selection GO:0045058 27 9 0,000 0,03955142 0,08446163 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03955142 0,08438787 ! glycine catabolic process GO:0006546 15 9 0,000 0,03955142 0,08431423 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03955142 0,08424072 ! endosome organization GO:0007032 20 9 0,000 0,03955142 0,08416734 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03955142 0,08409409 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03955142 0,08402096 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03955142 0,08394797 ! mannose metabolic process GO:0006013 13 9 0,000 0,03955142 0,0838751 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03955142 0,08380235 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03955142 0,08372973 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03955142 0,08365724 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03955142 0,08358487 ! receptor clustering GO:0043113 20 9 0,000 0,03955142 0,08351263 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03955142 0,08344051 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03955142 0,08336852 ! retinol metabolic process GO:0042572 20 9 0,000 0,03955142 0,08329665 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03955142 0,0832249 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03955142 0,08315328 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03955142 0,08308178 ! macrophage differentiation GO:0030225 15 9 0,000 0,03955142 0,0830104 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03955142 0,08293915 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,03955142 0,08286802 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03955142 0,08279701 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03955142 0,08272612 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03955142 0,08265535 ! response to amine stimulus GO:0014075 13 9 0,000 0,03955142 0,08258471 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03955142 0,08251418 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03955142 0,08244378 ! erythrocyte development GO:0048821 17 9 0,000 0,03955142 0,08237349 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03955142 0,08230333 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03955142 0,08223328 ! renal water homeostasis GO:0003091 15 9 0,000 0,03955142 0,08216336 ! postreplication repair GO:0006301 25 9 0,000 0,03955142 0,08209355 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03955142 0,08202386 ! icosanoid secretion GO:0032309 15 9 0,000 0,03955142 0,08195429 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03955142 0,08188484 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03955142 0,0818155 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03955142 0,08174629 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03955142 0,08167718 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03955142 0,0816082 ! sterol catabolic process GO:0016127 14 9 0,000 0,03955142 0,08153933 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03955142 0,08147058 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03955142 0,08140195 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03955142 0,08133343 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03955142 0,08126502 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03955142 0,08119673 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03955142 0,08112856 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,03955142 0,08106049 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03955142 0,08099255 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03955142 0,08092471 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03955142 0,080857 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03955142 0,08078939 ! purine base metabolic process GO:0006144 25 9 0,000 0,03955142 0,0807219 ! pigment granule transport GO:0051904 17 9 0,000 0,03955142 0,08065452 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,03955142 0,08058725 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03955142 0,08052009 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03955142 0,08045305 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03955142 0,08038611 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03955142 0,08031929 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03955142 0,08025258 ! mitochondrion localization GO:0051646 18 9 0,000 0,03955142 0,08018598 ! actin filament organization GO:0007015 167 72 1,000 0,04145077 0,08396702 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,04145077 0,08389746 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,04145077 0,083828 ! organelle localization GO:0051640 155 74 1,000 0,04355111 0,08800277 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04384891 0,0885313 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04384891 0,0884582 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04384891 0,08838521 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04384891 0,08831235 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04384891 0,0882396 ! phosphate transport GO:0006817 24 10 0,000 0,04384891 0,08816698 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04384891 0,08809447 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,04384891 0,08802209 ! CTP metabolic process GO:0046036 11 10 0,000 0,04384891 0,08794982 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04384891 0,08787767 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04384891 0,08780564 ! GTP metabolic process GO:0046039 11 10 0,000 0,04384891 0,08773373 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04384891 0,08766193 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04384891 0,08759025 ! social behavior GO:0035176 29 10 0,000 0,04384891 0,08751869 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04384891 0,08744725 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04384891 0,08737592 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04384891 0,08730471 ! androgen metabolic process GO:0008209 17 10 0,000 0,04384891 0,08723361 ! phospholipid efflux GO:0033700 19 10 0,000 0,04384891 0,08716264 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04384891 0,08709177 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04384891 0,08702102 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04384891 0,08695039 ! pathogenesis GO:0009405 17 10 0,000 0,04384891 0,08687987 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04384891 0,08680946 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,04384891 0,08673917 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04384891 0,086669 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04384891 0,08659893 ! endoderm development GO:0007492 18 10 0,000 0,04384891 0,08652898 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04384891 0,08645914 ! arginine catabolic process GO:0006527 17 10 0,000 0,04384891 0,08638942 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04384891 0,08631981 ! proline metabolic process GO:0006560 13 10 0,000 0,04384891 0,0862503 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04384891 0,08618092 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04384891 0,08611164 ! V(D)J recombination GO:0033151 34 10 0,000 0,04384891 0,08604247 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04384891 0,08597342 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04384891 0,08590447 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04384891 0,08583564 ! B cell proliferation GO:0042100 19 10 0,000 0,04384891 0,08576692 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04384891 0,0856983 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04384891 0,0856298 ! multicellular organism growth GO:0035264 19 10 0,000 0,04384891 0,0855614 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,04384891 0,08549312 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04384891 0,08542494 ! ruffle organization GO:0031529 17 10 0,000 0,04384891 0,08535688 ! epithelial cell development GO:0002064 21 10 0,000 0,04384891 0,08528892 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04384891 0,08522107 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04384891 0,08515332 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04384891 0,08508569 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04384891 0,08501816 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04384891 0,08495074 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,04384891 0,08488342 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04384891 0,08481621 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04384891 0,08474911 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04384891 0,08468212 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,04384891 0,08461523 ! segment specification GO:0007379 15 10 0,000 0,04384891 0,08454844 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04384891 0,08448177 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,04384891 0,08441519 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04384891 0,08434872 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04384891 0,08428236 ! response to dsRNA GO:0043331 23 10 0,000 0,04384891 0,0842161 ! DNA ligation GO:0006266 18 10 0,000 0,04384891 0,08414994 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04384891 0,08408389 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04384891 0,08401794 ! melanosome localization GO:0032400 16 10 0,000 0,04384891 0,0839521 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04384891 0,08388636 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04384891 0,08382072 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04384891 0,08375518 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04384891 0,08368975 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04384891 0,08362442 ! induction of an organ GO:0001759 17 10 0,000 0,04384891 0,08355919 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04384891 0,08349406 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04384891 0,08342903 ! protein sumoylation GO:0016925 17 10 0,000 0,04384891 0,08336411 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04384891 0,08329928 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04384891 0,08323456 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04384891 0,08316994 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04384891 0,08310541 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04384891 0,08304099 ! salivary gland development GO:0007431 28 10 0,000 0,04384891 0,08297667 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04384891 0,08291244 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04384891 0,08284832 ! midbrain development GO:0030901 14 10 0,000 0,04384891 0,0827843 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04384891 0,08272037 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04384891 0,08265654 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04384891 0,08259281 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04384891 0,08252918 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04384891 0,08246565 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04384891 0,08240221 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04384891 0,08233888 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04384891 0,08227564 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04384891 0,08221249 ! detection of calcium ion GO:0005513 24 10 0,000 0,04384891 0,08214945 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04384891 0,0820865 ! blastocyst formation GO:0001825 18 10 0,000 0,04384891 0,08202364 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04384891 0,08196089 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04384891 0,08189823 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04384891 0,08183566 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04384891 0,08177319 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04384891 0,08171082 ! rhythmic process GO:0048511 142 75 1,000 0,04461591 0,08307672 ! learning or memory GO:0007611 161 76 1,000 0,04569032 0,08501253 ! regulation of blood pressure GO:0008217 134 76 1,000 0,04569032 0,08494783 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,04569032 0,08488324 ! neurotransmitter transport GO:0006836 142 77 1,000 0,04677424 0,0868309 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,04677424 0,08676497 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,04677424 0,08669914 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,04786756 0,08865842 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,04812729 0,08907194 ! respiratory burst GO:0045730 17 11 0,000 0,04812729 0,08900452 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04812729 0,08893719 ! neuron fate specification GO:0048665 18 11 0,000 0,04812729 0,08886997 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04812729 0,08880284 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04812729 0,08873582 ! thyroid gland development GO:0030878 26 11 0,000 0,04812729 0,0886689 ! synapsis GO:0007129 14 11 0,000 0,04812729 0,08860208 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04812729 0,08853537 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04812729 0,08846875 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,04812729 0,08840223 ! response to pain GO:0048265 27 11 0,000 0,04812729 0,08833581 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04812729 0,08826949 ! bone resorption GO:0045453 16 11 0,000 0,04812729 0,08820328 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,04812729 0,08813716 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04812729 0,08807114 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04812729 0,08800521 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04812729 0,08793939 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04812729 0,08787367 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04812729 0,08780804 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,04812729 0,08774251 ! UV protection GO:0009650 20 11 0,000 0,04812729 0,08767708 ! adult heart development GO:0007512 16 11 0,000 0,04812729 0,08761175 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,04812729 0,08754651 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04812729 0,08748137 ! macroautophagy GO:0016236 19 11 0,000 0,04812729 0,08741633 ! temperature homeostasis GO:0001659 18 11 0,000 0,04812729 0,08735139 ! behavioral fear response GO:0001662 27 11 0,000 0,04812729 0,08728654 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04812729 0,08722178 ! negative regulation of ossification GO:0030279 27 11 0,000 0,04812729 0,08715713 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,04812729 0,08709257 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,04812729 0,0870281 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,04812729 0,08696373 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,04812729 0,08689946 ! regulation of organ growth GO:0046620 14 11 0,000 0,04812729 0,08683528 ! pigment granule localization GO:0051875 20 11 0,000 0,04812729 0,08677119 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04812729 0,0867072 ! vasoconstriction GO:0042310 20 11 0,000 0,04812729 0,08664331 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04812729 0,0865795 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04812729 0,0865158 ! embryonic axis specification GO:0000578 19 11 0,000 0,04812729 0,08645218 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04812729 0,08638866 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04812729 0,08632523 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04812729 0,0862619 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04812729 0,08619866 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04812729 0,08613551 GO:0006305|DNA alkylation, ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04812729 0,08607245 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04812729 0,08600948 ! prophase GO:0051324 17 11 0,000 0,04812729 0,08594661 ! neuroblast proliferation GO:0007405 25 11 0,000 0,04812729 0,08588383 ! nucleosome positioning GO:0016584 15 11 0,000 0,04812729 0,08582114 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04812729 0,08575855 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04812729 0,08569604 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04812729 0,08563362 ! apical protein localization GO:0045176 18 11 0,000 0,04812729 0,0855713 ! acid secretion GO:0046717 20 11 0,000 0,04812729 0,08550907 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04812729 0,08544692 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04812729 0,08538487 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04812729 0,08532291 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04812729 0,08526103 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,04812729 0,08519925 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,04812729 0,08513756 ! cholesterol efflux GO:0033344 21 11 0,000 0,04812729 0,08507595 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04812729 0,08501444 ! oocyte development GO:0048599 20 11 0,000 0,04812729 0,08495301 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,04812729 0,08489167 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,04812729 0,08483042 ! embryonic gut development GO:0048566 19 11 0,000 0,04812729 0,08476926 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04812729 0,08470819 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04812729 0,0846472 ! activation of innate immune response GO:0002218 16 11 0,000 0,04812729 0,08458631 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04812729 0,0845255 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,04812729 0,08446477 ! lysogeny GO:0030069 22 11 0,000 0,04812729 0,08440414 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04812729 0,08434359 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04812729 0,08428313 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04812729 0,08422275 ! nucleus localization GO:0051647 22 11 0,000 0,04812729 0,08416247 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,04897018 0,08557521 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,04897018 0,08551404 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,05008199 0,08739307 ! meiosis GO:0007126 143 81 1,000 0,05120289 0,08928526 GO:0051327|M phase of meiotic cell cycle, ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,05120289 0,08922158 ! protein import into nucleus GO:0006606 174 82 1,000 0,05233277 0,09112542 ! meiotic cell cycle GO:0051321 144 82 1,000 0,05233277 0,09106051 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05238665 0,09108938 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05238665 0,09102459 ! mating GO:0007618 17 12 0,000 0,05238665 0,0909599 ! protein complex disassembly GO:0043241 28 12 0,000 0,05238665 0,0908953 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05238665 0,09083079 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,05238665 0,09076637 ! hippocampus development GO:0021766 29 12 0,000 0,05238665 0,09070204 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,05238665 0,0906378 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05238665 0,09057366 ! T cell proliferation GO:0042098 32 12 0,000 0,05238665 0,0905096 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05238665 0,09044564 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05238665 0,09038176 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05238665 0,09031798 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05238665 0,09025429 ! drug transport GO:0015893 16 12 0,000 0,05238665 0,09019068 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05238665 0,09012717 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,05238665 0,09006374 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,05238665 0,09000041 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05238665 0,08993716 ! focal adhesion formation GO:0048041 37 12 0,000 0,05238665 0,089874 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05238665 0,08981093 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05238665 0,08974795 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05238665 0,08968506 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05238665 0,08962225 ! lipid digestion GO:0044241 21 12 0,000 0,05238665 0,08955954 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05238665 0,08949691 ! entry into host cell GO:0030260 34 12 0,000 0,05238665 0,08943437 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05238665 0,08937191 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05238665 0,08930954 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05238665 0,08924726 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05238665 0,08918507 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05238665 0,08912296 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05238665 0,08906094 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05238665 0,08899901 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05238665 0,08893716 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05238665 0,0888754 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05238665 0,08881372 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05238665 0,08875213 ! cranial nerve development GO:0021545 23 12 0,000 0,05238665 0,08869063 ! fucose catabolic process GO:0019317 25 12 0,000 0,05238665 0,08862921 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,05238665 0,08856787 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05238665 0,08850662 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05238665 0,08844546 ! zymogen activation GO:0031638 18 12 0,000 0,05238665 0,08838438 ! T cell homeostasis GO:0043029 28 12 0,000 0,05238665 0,08832338 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05238665 0,08826247 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05238665 0,08820164 ! oocyte differentiation GO:0009994 21 12 0,000 0,05238665 0,08814089 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05238665 0,08808023 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05238665 0,08801965 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05238665 0,08795916 ! defense response to fungus GO:0050832 15 12 0,000 0,05238665 0,08789875 ! developmental induction GO:0031128 22 12 0,000 0,05238665 0,08783842 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 0,000 0,05238665 0,08777817 ! response to cold GO:0009409 17 12 0,000 0,05238665 0,08771801 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05238665 0,08765793 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05238665 0,08759793 ! exocytosis GO:0006887 153 83 1,000 0,05347154 0,08935087 ! response to drug GO:0042493 149 83 1,000 0,05347154 0,0892898 ! nuclear import GO:0051170 177 83 1,000 0,05347154 0,08922881 ! response to metal ion GO:0010038 158 84 1,000 0,05461909 0,09108153 ! response to nutrient GO:0007584 135 84 1,000 0,05461909 0,09101941 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,05577533 0,09288285 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,05662706 0,094237 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05662706 0,09417285 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05662706 0,09410879 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05662706 0,09404481 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05662706 0,09398092 ! peroxisomal transport GO:0043574 28 13 0,000 0,05662706 0,09391712 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05662706 0,0938534 ! cartilage condensation GO:0001502 22 13 0,000 0,05662706 0,09378977 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05662706 0,09372623 ! organelle fusion GO:0048284 36 13 0,000 0,05662706 0,09366277 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05662706 0,0935994 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,05662706 0,09353612 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05662706 0,09347292 ! endocrine pancreas development GO:0031018 25 13 0,000 0,05662706 0,0934098 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,05662706 0,09334677 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05662706 0,09328383 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,05662706 0,09322097 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05662706 0,09315819 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05662706 0,0930955 ! methionine metabolic process GO:0006555 31 13 0,000 0,05662706 0,0930329 ! plasma membrane organization GO:0007009 27 13 0,000 0,05662706 0,09297037 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05662706 0,09290794 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05662706 0,09284558 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05662706 0,09278331 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05662706 0,09272112 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,05662706 0,09265902 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,05662706 0,092597 ! exocrine system development GO:0035272 34 13 0,000 0,05662706 0,09253506 ! asymmetric protein localization GO:0008105 24 13 0,000 0,05662706 0,09247321 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,05662706 0,09241143 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,05662706 0,09234974 ! L-glutamate transport GO:0015813 30 13 0,000 0,05662706 0,09228814 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,05662706 0,09222661 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05662706 0,09216517 ! protein homotetramerization GO:0051289 24 13 0,000 0,05662706 0,09210381 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05662706 0,09204253 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05662706 0,09198133 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05662706 0,09192021 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05662706 0,09185918 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05662706 0,09179822 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05662706 0,09173735 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05662706 0,09167655 ! chromatin silencing GO:0006342 29 13 0,000 0,05662706 0,09161584 ! gland morphogenesis GO:0022612 31 13 0,000 0,05662706 0,09155521 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05662706 0,09149465 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05662706 0,09143418 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05662706 0,09137379 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,05662706 0,09131348 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05662706 0,09125324 ! spleen development GO:0048536 24 13 0,000 0,05662706 0,09119309 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,05662706 0,09113302 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05662706 0,09107302 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05662706 0,0910131 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05662706 0,09095327 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05662706 0,09089351 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,05662706 0,09083383 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05662706 0,09077422 ! insulin secretion GO:0030073 24 13 0,000 0,05662706 0,0907147 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05662706 0,09065525 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,05662706 0,09059589 ! acrosome reaction GO:0007340 19 13 0,000 0,05662706 0,0905366 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05662706 0,09047738 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05662706 0,09041825 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,05694016 0,09085879 GO:0002696|positive regulation of leukocyte activation, ! nucleosome assembly GO:0006334 126 87 1,000 0,05811346 0,09267049 ! amine biosynthetic process GO:0009309 146 88 1,000 0,05929516 0,0944932 ! chromatin assembly GO:0031497 128 88 1,000 0,05929516 0,0944316 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,05929516 0,09437008 ! protein localization in nucleus GO:0034504 192 89 1,000 0,06048515 0,09620131 ! regulation of neurological system process GO:0031644 175 89 1,000 0,06048515 0,09613872 ! rRNA transcription GO:0009303 28 14 0,000 0,06084863 0,09665357 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,06084863 0,09659077 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,06084863 0,09652805 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,06084863 0,09646541 ! non-recombinational repair GO:0000726 29 14 0,000 0,06084863 0,09640285 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,06084863 0,09634037 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,06084863 0,09627797 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,06084863 0,09621566 ! RNA polyadenylation GO:0043631 32 14 0,000 0,06084863 0,09615342 ! lipid localization GO:0010876 32 14 0,000 0,06084863 0,09609127 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,06084863 0,09602919 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,06084863 0,0959672 ! regulated secretory pathway GO:0045055 24 14 0,000 0,06084863 0,09590529 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,06084863 0,09584345 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,06084863 0,0957817 ! arginine metabolic process GO:0006525 21 14 0,000 0,06084863 0,09572002 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,06084863 0,09565842 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,06084863 0,09559691 ! fear response GO:0042596 34 14 0,000 0,06084863 0,09553547 ! organic alcohol transport GO:0015850 29 14 0,000 0,06084863 0,09547411 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,06084863 0,09541283 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06084863 0,09535163 ! neutral amino acid transport GO:0015804 28 14 0,000 0,06084863 0,09529051 ! bone mineralization GO:0030282 18 14 0,000 0,06084863 0,09522946 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,06084863 0,0951685 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,06084863 0,09510761 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,06084863 0,0950468 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,06084863 0,09498607 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,06084863 0,09492541 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,06084863 0,09486483 ! ribosome assembly GO:0042255 18 14 0,000 0,06084863 0,09480433 ! cerebellum development GO:0021549 23 14 0,000 0,06084863 0,09474391 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,06084863 0,09468356 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,06084863 0,09462329 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,06084863 0,0945631 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,06084863 0,09450298 ! NADP metabolic process GO:0006739 24 14 0,000 0,06084863 0,09444294 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,06084863 0,09438298 ! oxygen transport GO:0015671 22 14 0,000 0,06084863 0,09432309 ! male genitalia development GO:0030539 26 14 0,000 0,06084863 0,09426328 ! regulation of axon extension GO:0030516 43 14 0,000 0,06084863 0,09420354 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,06084863 0,09414388 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,06084863 0,0940843 ! response to inorganic substance GO:0010035 173 90 1,000 0,06168332 0,09531459 ! response to unfolded protein GO:0006986 139 90 1,000 0,06168332 0,09525434 ! ossification GO:0001503 205 91 1,000 0,0628896 0,09705578 ! bone development GO:0060348 206 92 1,000 0,06410388 0,09886728 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,06410388 0,0988049 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06505141 0,10020215 ! lactation GO:0007595 30 15 0,000 0,06505141 0,10013901 ! reproductive cellular process GO:0048610 22 15 0,000 0,06505141 0,10007595 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06505141 0,10001297 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,06505141 0,09995007 ! superoxide anion generation GO:0042554 22 15 0,000 0,06505141 0,09988724 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,06505141 0,0998245 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,06505141 0,09976184 ! copper ion transport GO:0006825 22 15 0,000 0,06505141 0,09969925 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,06505141 0,09963674 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,06505141 0,09957431 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,06505141 0,09951196 ! sulfate transport GO:0008272 27 15 0,000 0,06505141 0,09944969 ! response to cAMP GO:0051591 25 15 0,000 0,06505141 0,09938749 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,06505141 0,09932538 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,06505141 0,09926334 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,06505141 0,09920138 ! response to hexose stimulus GO:0009746 25 15 0,000 0,06505141 0,09913949 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,06505141 0,09907768 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,06505141 0,09901595 ! vesicle coating GO:0006901 38 15 0,000 0,06505141 0,0989543 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,06505141 0,09889272 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,06505141 0,09883122 ! regulation of exocytosis GO:0017157 26 15 0,000 0,06505141 0,0987698 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,06505141 0,09870845 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,06505141 0,09864718 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,06505141 0,09858598 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,06505141 0,09852486 ! regulation of vasodilation GO:0042312 27 15 0,000 0,06505141 0,09846382 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,06505141 0,09840285 ! histone deacetylation GO:0016575 24 15 0,000 0,06505141 0,09834196 ! water homeostasis GO:0030104 28 15 0,000 0,06505141 0,09828114 ! cofactor transport GO:0051181 30 15 0,000 0,06505141 0,0982204 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,06505141 0,09815973 ! intestinal absorption GO:0050892 31 15 0,000 0,06505141 0,09809914 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,06505141 0,09803862 ! heme biosynthetic process GO:0006783 33 15 0,000 0,06505141 0,09797818 ! cell killing GO:0001906 32 15 0,000 0,06505141 0,09791781 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,06505141 0,09785751 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,06505141 0,09779729 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,06505141 0,09773715 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,06505141 0,09767708 ! actin filament polymerization GO:0030041 27 15 0,000 0,06505141 0,09761708 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,06505141 0,09755715 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,06532606 0,09790894 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,06532606 0,09784891 GO:0010498|proteasomal protein catabolic process, ! regulation of membrane potential GO:0042391 179 94 1,000 0,06655606 0,09963018 ! regulation of defense response GO:0031347 171 95 1,000 0,06779378 0,10142082 ! nucleosome organization GO:0034728 143 95 1,000 0,06779378 0,10135875 ! response to protein stimulus GO:0051789 158 96 1,000 0,06903912 0,10315754 ! regulation of T cell activation GO:0050863 175 96 1,000 0,06903912 0,10309449 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,06923551 0,10332459 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06923551 0,10326151 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,06923551 0,10319851 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,06923551 0,10313558 ! bone remodeling GO:0046849 28 16 0,000 0,06923551 0,10307273 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,06923551 0,10300996 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,06923551 0,10294726 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06923551 0,10288464 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,06923551 0,1028221 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06923551 0,10275963 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06923551 0,10269724 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,06923551 0,10263492 ! startle response GO:0001964 28 16 0,000 0,06923551 0,10257268 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06923551 0,10251052 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,06923551 0,10244843 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06923551 0,10238641 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06923551 0,10232447 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06923551 0,10226261 ! pituitary gland development GO:0021983 30 16 0,000 0,06923551 0,10220082 ! response to osmotic stress GO:0006970 27 16 0,000 0,06923551 0,1021391 ! lysosomal transport GO:0007041 31 16 0,000 0,06923551 0,10207746 ! fructose metabolic process GO:0006000 25 16 0,000 0,06923551 0,1020159 ! L-amino acid transport GO:0015807 33 16 0,000 0,06923551 0,1019544 ! stem cell development GO:0048864 46 16 0,000 0,06923551 0,10189299 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06923551 0,10183164 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06923551 0,10177037 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06923551 0,10170917 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,06923551 0,10164805 ! negative regulation of immune response GO:0050777 38 16 0,000 0,06923551 0,101587 ! axon cargo transport GO:0008088 46 16 0,000 0,06923551 0,10152602 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06923551 0,10146512 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06923551 0,10140429 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,06923551 0,10134353 ! DNA replication initiation GO:0006270 28 16 0,000 0,06923551 0,10128285 ! neuron recognition GO:0008038 40 16 0,000 0,06923551 0,10122224 ! mRNA splice site selection GO:0006376 44 16 0,000 0,06923551 0,1011617 ! tissue regeneration GO:0042246 27 16 0,000 0,06923551 0,10110123 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06923551 0,10104083 ! biomineral formation GO:0031214 22 16 0,000 0,06923551 0,10098051 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06923551 0,10092026 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06923551 0,10086008 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,06923551 0,10079997 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06923551 0,10073994 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06923551 0,10067997 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06923551 0,10062008 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06923551 0,10056026 ! peptide hormone processing GO:0016486 27 16 0,000 0,06923551 0,10050051 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,070292 0,1019735 ! transcription initiation GO:0006352 171 97 1,000 0,070292 0,10191298 ! leukocyte differentiation GO:0002521 232 98 1,000 0,07155233 0,10367873 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,073401 0,1062944 ! metencephalon development GO:0022037 32 17 0,000 0,073401 0,10623143 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,073401 0,10616853 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,073401 0,10610571 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,073401 0,10604296 ! signal complex assembly GO:0007172 47 17 0,000 0,073401 0,10598029 ! filopodium assembly GO:0046847 42 17 0,000 0,073401 0,10591769 ! endothelial cell migration GO:0043542 31 17 0,000 0,073401 0,10585516 ! gene silencing by RNA GO:0031047 38 17 0,000 0,073401 0,10579271 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,073401 0,10573034 ! glial cell development GO:0021782 28 17 0,000 0,073401 0,10566803 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,073401 0,1056058 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,073401 0,10554364 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,073401 0,10548156 ! myoblast differentiation GO:0045445 50 17 0,000 0,073401 0,10541955 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,073401 0,10535761 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,073401 0,10529574 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,073401 0,10523395 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,073401 0,10517223 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,073401 0,10511058 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,073401 0,105049 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,073401 0,1049875 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,073401 0,10492607 ! membrane budding GO:0006900 42 17 0,000 0,073401 0,10486471 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,073401 0,10480342 ! regulation of protein binding GO:0043393 33 17 0,000 0,073401 0,1047422 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,073401 0,10468106 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,073401 0,10461998 ! genitalia development GO:0048806 32 17 0,000 0,073401 0,10455898 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,073401 0,10449805 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,073401 0,10443719 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,073401 0,1043764 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,073401 0,10431568 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,073401 0,10425503 ! steroid catabolic process GO:0006706 34 17 0,000 0,073401 0,10419445 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,073401 0,10413394 ! gas transport GO:0015669 26 17 0,000 0,073401 0,10407351 ! organic cation transport GO:0015695 32 17 0,000 0,073401 0,10401314 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,073401 0,10395284 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,073401 0,10389261 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,07409495 0,1048141 GO:0060538|skeletal muscle organ development, ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,07754797 0,10963523 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,07754797 0,10957183 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,07754797 0,10950849 ! limbic system development GO:0021761 40 18 0,000 0,07754797 0,10944523 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07754797 0,10938204 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,07754797 0,10931892 ! adult walking behavior GO:0007628 36 18 0,000 0,07754797 0,10925587 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,07754797 0,1091929 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,07754797 0,10913 ! centrosome cycle GO:0007098 26 18 0,000 0,07754797 0,10906718 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,07754797 0,10900442 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,07754797 0,10894174 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,07754797 0,10887913 ! glycine metabolic process GO:0006544 30 18 0,000 0,07754797 0,10881659 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07754797 0,10875413 ! response to retinoic acid GO:0032526 31 18 0,000 0,07754797 0,10869173 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,07754797 0,10862941 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,07754797 0,10856716 ! DNA integration GO:0015074 32 18 0,000 0,07754797 0,10850497 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,07754797 0,10844287 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,07754797 0,10838083 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,07754797 0,10831886 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,07754797 0,10825696 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,07754797 0,10819514 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,07754797 0,10813338 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,07754797 0,1080717 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,07754797 0,10801008 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,07754797 0,10794854 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,07754797 0,10788706 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,07754797 0,10782566 ! detection of bacterium GO:0016045 22 18 0,000 0,07754797 0,10776433 ! nerve development GO:0021675 34 18 0,000 0,07754797 0,10770306 ! defense response to virus GO:0051607 43 18 0,000 0,07754797 0,10764187 ! microspike assembly GO:0030035 46 18 0,000 0,07754797 0,10758074 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,07754797 0,10751969 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,07754797 0,1074587 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,08167649 0,11311546 ! positive regulation of translation GO:0045727 31 19 0,000 0,08167649 0,11305137 ! neuron maturation GO:0042551 46 19 0,000 0,08167649 0,11298735 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,08167649 0,11292341 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,08167649 0,11285954 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,08167649 0,11279574 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,08167649 0,11273201 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,08167649 0,11266836 ! inositol metabolic process GO:0006020 33 19 0,000 0,08167649 0,11260478 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08167649 0,11254127 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,08167649 0,11247783 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,08167649 0,11241446 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,08167649 0,11235116 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,08167649 0,11228794 ! cerebral cortex development GO:0021987 40 19 0,000 0,08167649 0,11222478 ! pigmentation during development GO:0048066 42 19 0,000 0,08167649 0,1121617 ! response to vitamin A GO:0033189 32 19 0,000 0,08167649 0,11209869 ! heme metabolic process GO:0042168 40 19 0,000 0,08167649 0,11203575 ! neuromuscular junction development GO:0007528 43 19 0,000 0,08167649 0,11197288 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,08167649 0,11191008 ! response to fungus GO:0009620 26 19 0,000 0,08167649 0,11184735 ! peptide cross-linking GO:0018149 39 19 0,000 0,08167649 0,11178469 ! protein export from nucleus GO:0006611 40 19 0,000 0,08167649 0,1117221 ! heart process GO:0003015 32 19 0,000 0,08167649 0,11165958 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,08167649 0,11159713 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,08167649 0,11153475 ! visual learning GO:0008542 38 19 0,000 0,08167649 0,11147244 ! cellular pigmentation GO:0033059 37 19 0,000 0,08167649 0,1114102 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,08167649 0,11134803 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,08167649 0,11128593 ! vitamin transport GO:0051180 31 19 0,000 0,08167649 0,11122389 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,08167649 0,11116193 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,08167649 0,11110004 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,08167649 0,11103821 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,08167649 0,11097645 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,08167649 0,11091477 ! cilium assembly GO:0042384 38 19 0,000 0,08167649 0,11085315 ! peptide hormone secretion GO:0030072 32 19 0,000 0,08167649 0,1107916 ! protein secretion GO:0009306 45 20 0,000 0,08578665 0,11630232 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,08578665 0,11623782 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,08578665 0,11617338 ! positive regulation of ossification GO:0045778 50 20 0,000 0,08578665 0,11610902 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,08578665 0,11604473 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,08578665 0,11598051 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,08578665 0,11591636 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,08578665 0,11585229 ! response to vitamin GO:0033273 36 20 0,000 0,08578665 0,11578828 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,08578665 0,11572434 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,08578665 0,11566048 ! bile acid metabolic process GO:0008206 34 20 0,000 0,08578665 0,11559668 ! retinoid metabolic process GO:0001523 34 20 0,000 0,08578665 0,11553296 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,08578665 0,1154693 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,08578665 0,11540572 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,08578665 0,1153422 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,08578665 0,11527876 ! body fluid secretion GO:0007589 33 20 0,000 0,08578665 0,11521539 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,08578665 0,11515208 ! peptide secretion GO:0002790 38 20 0,000 0,08578665 0,11508884 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,08578665 0,11502568 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,08578665 0,11496258 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,08578665 0,11489955 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,08578665 0,1148366 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,08578665 0,11477371 ! cell-cell junction organization GO:0045216 43 20 0,000 0,08578665 0,11471088 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,08578665 0,11464813 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,08578665 0,11458545 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,08578665 0,11452283 ! regulation of glucose import GO:0046324 30 20 0,000 0,08578665 0,11446029 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,08578665 0,11439781 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,08578665 0,1143354 ! negative regulation of translation GO:0017148 32 20 0,000 0,08578665 0,11427306 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,08578665 0,11421078 ! regulation of cell killing GO:0031341 46 21 0,000 0,08987853 0,11959327 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,08987853 0,11952817 ! hormone secretion GO:0046879 39 21 0,000 0,08987853 0,11946314 ! cAMP metabolic process GO:0046058 41 21 0,000 0,08987853 0,11939818 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,08987853 0,11933329 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,08987853 0,11926847 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,08987853 0,11920372 ! ovarian follicle development GO:0001541 39 21 0,000 0,08987853 0,11913904 ! smooth muscle contraction GO:0006939 48 21 0,000 0,08987853 0,11907443 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,08987853 0,11900989 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,08987853 0,11894542 ! plasma membrane fusion GO:0045026 33 21 0,000 0,08987853 0,11888102 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,08987853 0,11881669 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,08987853 0,11875243 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,08987853 0,11868824 ! sensory perception of pain GO:0019233 33 21 0,000 0,08987853 0,11862412 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,08987853 0,11856007 ! diencephalon development GO:0021536 36 21 0,000 0,08987853 0,11849609 ! collagen fibril organization GO:0030199 62 21 0,000 0,08987853 0,11843217 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,08987853 0,11836833 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,08987853 0,11830455 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,08987853 0,11824084 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,08987853 0,11817721 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,08987853 0,11811364 ! collagen catabolic process GO:0030574 29 21 0,000 0,08987853 0,11805013 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,08987853 0,1179867 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,08987853 0,11792333 ! sperm-egg recognition GO:0035036 23 21 0,000 0,08987853 0,11786004 ! actin filament-based movement GO:0030048 47 21 0,000 0,08987853 0,11779681 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,09395221 0,12306984 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,09395221 0,12300388 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,09395221 0,122938 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,09395221 0,12287219 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,09395221 0,12280645 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 59 22 0,000 0,09395221 0,12274077 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,09395221 0,12267517 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,09395221 0,12260964 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,09395221 0,12254418 ! vacuolar transport GO:0007034 41 22 0,000 0,09395221 0,12247879 ! central nervous system neuron development GO:0021954 47 22 0,000 0,09395221 0,12241346 ! fucose metabolic process GO:0006004 44 22 0,000 0,09395221 0,12234821 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,09395221 0,12228303 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,09395221 0,12221792 ! ureteric bud development GO:0001657 50 22 0,000 0,09395221 0,12215287 ! stem cell differentiation GO:0048863 57 22 0,000 0,09395221 0,1220879 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,09395221 0,12202299 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,09395221 0,12195815 ! cytolysis GO:0019835 27 22 0,000 0,09395221 0,12189339 ! renal system process GO:0003014 42 22 0,000 0,09395221 0,12182869 ! vasodilation GO:0042311 40 22 0,000 0,09395221 0,12176406 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,09395221 0,12169949 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,09395221 0,121635 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,09395221 0,12157058 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,09395221 0,12150622 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,09395221 0,12144193 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,09395221 0,12137771 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,09395221 0,12131356 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,09395221 0,12124947 ! sarcomere organization GO:0045214 32 22 0,000 0,09395221 0,12118545 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,09395221 0,1211215 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,09395221 0,12105762 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,09395221 0,1209938 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,09395221 0,12093006 ! gut development GO:0048565 44 22 0,000 0,09395221 0,12086638 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,09395221 0,12080276 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,09395221 0,12073921 ! protein stabilization GO:0050821 41 22 0,000 0,09395221 0,12067573 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,09800777 0,1258187 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,09800777 0,12575262 ! gluconeogenesis GO:0006094 38 23 0,000 0,09800777 0,1256866 ! glycerol metabolic process GO:0006071 40 23 0,000 0,09800777 0,12562066 ! viral genome replication GO:0019079 44 23 0,000 0,09800777 0,12555479 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,09800777 0,12548898 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,09800777 0,12542325 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,09800777 0,12535758 ! regeneration GO:0031099 42 23 0,000 0,09800777 0,12529198 ! axis specification GO:0009798 43 23 0,000 0,09800777 0,12522645 ! visual behavior GO:0007632 46 23 0,000 0,09800777 0,12516099 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,09800777 0,1250956 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,09800777 0,12503028 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,09800777 0,12496502 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,09800777 0,12489983 ! peroxisome organization GO:0007031 43 23 0,000 0,09800777 0,12483471 ! lysosome organization GO:0007040 47 23 0,000 0,09800777 0,12476966 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,09800777 0,12470468 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,09800777 0,12463976 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,09800777 0,12457491 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,09800777 0,12451013 ! DNA modification GO:0006304 36 23 0,000 0,09800777 0,12444542 ! fatty acid transport GO:0015908 47 23 0,000 0,09800777 0,12438077 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,09800777 0,12431619 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,09800777 0,12425168 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,09800777 0,12418723 ! hormone transport GO:0009914 41 23 0,000 0,09800777 0,12412285 ! cell-cell recognition GO:0009988 28 23 0,000 0,09800777 0,12405854 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,09800777 0,12399429 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,09800777 0,12393011 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,10204529 0,12896877 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,10204529 0,12890209 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,10204529 0,12883547 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,10204529 0,12876893 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,10204529 0,12870245 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,10204529 0,12863604 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,10204529 0,1285697 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,10204529 0,12850342 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,10204529 0,12843722 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,10204529 0,12837108 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,10204529 0,12830501 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,10204529 0,12823901 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,10204529 0,12817308 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,10204529 0,12810722 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,10204529 0,12804142 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,10204529 0,12797569 ! membrane depolarization GO:0051899 45 24 0,000 0,10204529 0,12791003 ! pallium development GO:0021543 56 24 0,000 0,10204529 0,12784443 ! oogenesis GO:0048477 44 24 0,000 0,10204529 0,1277789 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,10204529 0,12771344 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,10204529 0,12764805 ! platelet activation GO:0030168 41 24 0,000 0,10204529 0,12758272 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,10204529 0,12751746 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,10204529 0,12745227 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,10204529 0,12738714 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,10204529 0,12732208 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,10204529 0,12725709 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,10204529 0,12719216 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,10204529 0,1271273 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,10606485 0,1320675 ! leukocyte adhesion GO:0007159 55 25 0,000 0,10606485 0,13200022 ! phototransduction GO:0007602 37 25 0,000 0,10606485 0,13193301 ! keratinization GO:0031424 37 25 0,000 0,10606485 0,13186587 ! vacuole organization GO:0007033 49 25 0,000 0,10606485 0,13179879 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,10606485 0,13173179 ! receptor metabolic process GO:0043112 53 25 0,000 0,10606485 0,13166485 ! chromosome condensation GO:0030261 48 25 0,000 0,10606485 0,13159798 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,10606485 0,13153118 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,10606485 0,13146445 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,10606485 0,13139778 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,10606485 0,13133119 ! immunoglobulin production GO:0002377 62 25 0,000 0,10606485 0,13126465 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,10606485 0,13119819 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,10606485 0,1311318 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,10606485 0,13106547 ! liver development GO:0001889 55 25 0,000 0,10606485 0,13099921 ! myelination GO:0042552 50 26 0,000 0,11006653 0,13587293 ! initiation of viral infection GO:0019059 60 26 0,000 0,11006653 0,13580431 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,11006653 0,13573576 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,11006653 0,13566727 ! molting cycle process GO:0022404 52 26 0,000 0,11006653 0,13559886 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,11006653 0,13553051 ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,11006653 0,13546223 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,11006653 0,13539403 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,11006653 0,13532589 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,11006653 0,13525781 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,11006653 0,13518981 ! digestive system process GO:0022600 49 26 0,000 0,11006653 0,13512188 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,11006653 0,13505401 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,11006653 0,13498621 ! osteoblast differentiation GO:0001649 63 26 0,000 0,11006653 0,13491848 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,11006653 0,13485082 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,11006653 0,13478323 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,11006653 0,1347157 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,11006653 0,13464824 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,11006653 0,13458085 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,11006653 0,13451352 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,11006653 0,13444627 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,11006653 0,13437908 ! blastocyst development GO:0001824 50 26 0,000 0,11006653 0,13431196 ! telomere organization GO:0032200 46 26 0,000 0,11006653 0,1342449 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,11006653 0,13417791 ! neural tube closure GO:0001843 58 26 0,000 0,11006653 0,13411099 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,11006653 0,13404413 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,11006653 0,13397735 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,11006653 0,13391062 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,11405041 0,13868848 ! embryonic pattern specification GO:0009880 49 27 0,000 0,11405041 0,13861948 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,11405041 0,13855055 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,11405041 0,13848169 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,11405041 0,13841289 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,11405041 0,13834417 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,11405041 0,13827551 ! iron ion transport GO:0006826 65 27 0,000 0,11405041 0,13820692 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,11405041 0,1381384 ! superoxide metabolic process GO:0006801 41 27 0,000 0,11405041 0,13806995 ! tube lumen formation GO:0035148 59 27 0,000 0,11405041 0,13800156 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,11405041 0,13793324 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,11405041 0,13786499 ! response to toxin GO:0009636 49 27 0,000 0,11405041 0,13779681 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,11405041 0,1377287 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,11405041 0,13766065 ! leukocyte proliferation GO:0070661 59 27 0,000 0,11405041 0,13759267 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,11801657 0,14230724 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,11801657 0,14223704 ! vesicle docking GO:0048278 55 28 0,000 0,11801657 0,1421669 ! circadian rhythm GO:0007623 56 28 0,000 0,11801657 0,14209683 ! dendrite development GO:0016358 67 28 0,000 0,11801657 0,14202683 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,11801657 0,1419569 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,11801657 0,14188704 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,11801657 0,14181725 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,11801657 0,14174753 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,11801657 0,14167787 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,11801657 0,14160829 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,11801657 0,14153877 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,11801657 0,14146932 ! glutathione metabolic process GO:0006749 42 28 0,000 0,11801657 0,14139994 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,11801657 0,14133062 ! lipid oxidation GO:0034440 48 28 0,000 0,11801657 0,14126138 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,11801657 0,1411922 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,11801657 0,14112309 ! translational initiation GO:0006413 66 29 0,000 0,12196508 0,14577333 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,12196508 0,14570205 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,12196508 0,14563083 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,12196508 0,14555969 ! primary neural tube formation GO:0014020 61 29 0,000 0,12196508 0,14548862 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,12196508 0,14541761 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,12196508 0,14534668 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,12196508 0,14527581 ! synaptogenesis GO:0007416 46 29 0,000 0,12196508 0,14520501 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,12196508 0,14513429 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,12196508 0,14506363 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,12196508 0,14499304 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,12196508 0,14492251 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,12589602 0,14952066 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,12589602 0,149448 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,12589602 0,14937542 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,12589602 0,14930291 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,12589602 0,14923047 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,12589602 0,14915809 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,12589602 0,14908579 ! acute-phase response GO:0006953 50 30 0,000 0,12589602 0,14901356 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,12589602 0,1489414 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,12589602 0,14886931 ! myofibril assembly GO:0030239 50 30 0,000 0,12589602 0,14879729 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,12589602 0,14872533 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,12589602 0,14865345 ! cell fate determination GO:0001709 64 30 0,000 0,12589602 0,14858164 ! phospholipid transport GO:0015914 65 30 0,000 0,12589602 0,14850989 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,12589602 0,14843822 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,12589602 0,14836661 GO:0046496|nicotinamide nucleotide metabolic process, ! tissue homeostasis GO:0001894 50 30 0,000 0,12589602 0,14829508 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,12589602 0,14822361 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,12980948 0,1527575 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,12980948 0,15268395 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,12980948 0,15261047 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,12980948 0,15253707 ! cell junction assembly GO:0034329 85 31 0,000 0,12980948 0,15246373 ! regulation of innate immune response GO:0045088 57 31 0,000 0,12980948 0,15239047 ! peptide transport GO:0015833 60 31 0,000 0,12980948 0,15231727 ! male gonad development GO:0008584 56 31 0,000 0,12980948 0,15224415 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,12980948 0,1521711 ! detection of light stimulus GO:0009583 44 31 0,000 0,12980948 0,15209811 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,12980948 0,1520252 ! natural killer cell activation GO:0030101 50 31 0,000 0,12980948 0,15195236 ! ensheathment of neurons GO:0007272 64 31 0,000 0,12980948 0,15187958 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,12980948 0,15180688 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,12980948 0,15173424 ! eye morphogenesis GO:0048592 65 31 0,000 0,12980948 0,15166168 ! response to heat GO:0009408 54 31 0,000 0,12980948 0,15158918 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,12980948 0,15151675 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,13370553 0,15598978 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,13370553 0,15591533 ! spindle organization GO:0007051 50 32 0,000 0,13370553 0,15584094 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,13370553 0,15576662 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,13370553 0,15569238 ! metanephros development GO:0001656 81 32 0,000 0,13370553 0,1556182 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,13370553 0,1555441 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,13370553 0,15547007 ! muscle cell development GO:0055001 52 32 0,000 0,13370553 0,1553961 ! mesoderm formation GO:0001707 73 32 0,000 0,13370553 0,15532221 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,13370553 0,15524839 ! peripheral nervous system development GO:0007422 68 32 0,000 0,13370553 0,15517464 ! BMP signaling pathway GO:0030509 71 32 0,000 0,13370553 0,15510095 ! hindbrain development GO:0030902 65 32 0,000 0,13370553 0,15502734 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,13370553 0,1549538 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,13370553 0,15488033 ! gene silencing GO:0016458 71 32 0,000 0,13370553 0,15480692 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,13758424 0,15922231 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,13758424 0,15914692 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,13758424 0,1590716 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,13758424 0,15899636 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,13758424 0,15892118 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,13758424 0,15884608 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,13758424 0,15877104 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,13758424 0,15869608 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,13758424 0,15862119 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,1414457 0,16299615 ! glial cell differentiation GO:0010001 67 34 0,000 0,1414457 0,1629193 ! post-embryonic development GO:0009791 76 34 0,000 0,1414457 0,16284252 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,1414457 0,16276582 ! cholesterol transport GO:0030301 62 34 0,000 0,1414457 0,16268919 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,1414457 0,16261263 ! spliceosome assembly GO:0000245 75 34 0,000 0,1414457 0,16253614 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,1414457 0,16245972 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,1414457 0,16238338 ! formation of primary germ layer GO:0001704 76 34 0,000 0,1414457 0,16230711 ! cell fate specification GO:0001708 56 34 0,000 0,1414457 0,16223091 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,1414457 0,16215478 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,1414457 0,16207872 ! adult locomotory behavior GO:0008344 62 34 0,000 0,1414457 0,16200273 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,14528997 0,16632774 ! negative regulation of secretion GO:0051048 68 35 0,000 0,14528997 0,16624983 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,14528997 0,166172 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,14528997 0,16609424 ! membrane docking GO:0022406 69 35 0,000 0,14528997 0,16601655 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,14528997 0,16593894 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,14528997 0,1658614 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,14528997 0,16578393 ! ceramide metabolic process GO:0006672 72 35 0,000 0,14528997 0,16570653 ! telencephalon development GO:0021537 81 35 0,000 0,14528997 0,16562921 ! sterol transport GO:0015918 63 35 0,000 0,14528997 0,16555196 ! regulation of muscle development GO:0048634 82 36 0,000 0,14911714 0,16983364 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,14911714 0,1697545 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,14911714 0,16967544 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,14911714 0,16959644 ! protein targeting to membrane GO:0006612 75 36 0,000 0,14911714 0,16951753 ! regulation of proteolysis GO:0030162 77 36 0,000 0,14911714 0,16943868 ! aerobic respiration GO:0009060 56 36 0,000 0,14911714 0,16935991 ! cytokine production GO:0001816 68 36 0,000 0,14911714 0,16928121 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,14911714 0,16920258 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,14911714 0,16912403 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,15292727 0,17336489 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,15292727 0,17328448 ! sister chromatid segregation GO:0000819 65 37 0,000 0,15292727 0,17320414 ! odontogenesis GO:0042476 74 37 0,000 0,15292727 0,17312388 ! actomyosin structure organization GO:0031032 68 37 0,000 0,15292727 0,17304369 ! cell junction organization GO:0034330 96 37 0,000 0,15292727 0,17296358 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,15292727 0,17288354 ! female gonad development GO:0008585 71 37 0,000 0,15292727 0,17280358 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,15292727 0,17272368 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,15292727 0,17264387 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,15672046 0,17684438 ! meiosis I GO:0007127 74 38 0,000 0,15672046 0,17676273 ! organic anion transport GO:0015711 82 38 0,000 0,15672046 0,17668116 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,15672046 0,17659967 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,15672046 0,17651825 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,15672046 0,1764369 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,15672046 0,17635563 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,15672046 0,17627444 ! spermatid development GO:0007286 69 38 0,000 0,15672046 0,17619332 ! glycogen metabolic process GO:0005977 63 38 0,000 0,15672046 0,17611227 ! pigment metabolic process GO:0042440 87 38 0,000 0,15672046 0,1760313 ! neural tube formation GO:0001841 79 38 0,000 0,15672046 0,1759504 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,16049676 0,1801073 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,16049676 0,1800246 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,16049676 0,17994199 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,16049676 0,17985944 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,16049676 0,17977698 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,16049676 0,17969459 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,16049676 0,17961227 ! glucan metabolic process GO:0044042 64 39 0,000 0,16049676 0,17953003 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,16425626 0,18365128 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,16425626 0,18356727 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,16425626 0,18348333 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,16425626 0,18339947 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,16425626 0,18331569 ! mismatch repair GO:0006298 58 40 0,000 0,16425626 0,18323198 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,16425626 0,18314835 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,16425626 0,1830648 ! RNA export from nucleus GO:0006405 61 41 0,000 0,16799903 0,18715076 ! mRNA catabolic process GO:0006402 79 41 0,000 0,16799903 0,18706546 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,16799903 0,18698024 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,16799903 0,18689509 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,16799903 0,18681003 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,16799903 0,18672504 ! feeding behavior GO:0007631 69 41 0,000 0,16799903 0,18664012 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,16799903 0,18655529 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,16799903 0,18647053 ! spermatid differentiation GO:0048515 73 41 0,000 0,16799903 0,18638584 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,16799903 0,18630124 ! RNA modification GO:0009451 64 41 0,000 0,16799903 0,18621671 ! ear morphogenesis GO:0042471 64 42 0,000 0,17172514 0,19026055 ! organic ether metabolic process GO:0018904 59 42 0,000 0,17172514 0,19017431 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,17172514 0,19008814 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,17172514 0,19000205 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,17172514 0,18991603 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,17172514 0,1898301 ! regulation of protein secretion GO:0050708 77 42 0,000 0,17172514 0,18974424 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,17172514 0,18965846 ! cytokinesis GO:0000910 84 42 0,000 0,17172514 0,18957276 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,17172514 0,18948714 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,17543467 0,19349296 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,17543467 0,19340564 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,17543467 0,1933184 ! regulation of tube size GO:0035150 76 43 0,000 0,17543467 0,19323124 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,17543467 0,19314416 ! glucose transport GO:0015758 66 43 0,000 0,17543467 0,19305716 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,17543467 0,19297024 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,17543467 0,19288339 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,17543467 0,19279663 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,17543467 0,19270994 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,17543467 0,19262333 ! ion transmembrane transport GO:0034220 79 43 0,000 0,17543467 0,19253679 ! neuron migration GO:0001764 85 43 0,000 0,17543467 0,19245034 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,17912769 0,19641335 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,17912769 0,19632523 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,17912769 0,1962372 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,17912769 0,19614924 ! hexose transport GO:0008645 68 44 0,000 0,17912769 0,19606136 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,17912769 0,19597355 ! phagocytosis GO:0006909 105 44 0,000 0,17912769 0,19588583 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,17912769 0,19579819 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,18280427 0,19972757 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,18280427 0,19963828 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,18280427 0,19954908 ! female gamete generation GO:0007292 71 45 0,000 0,18280427 0,19945995 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,18280427 0,19937091 ! polyol metabolic process GO:0019751 77 45 0,000 0,18280427 0,19928194 ! developmental growth GO:0048589 88 45 0,000 0,18280427 0,19919306 ! maintenance of location in cell GO:0051651 101 45 0,000 0,18280427 0,19910425 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,18646449 0,20300034 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,18646449 0,20290991 ! glycolysis GO:0006096 71 46 0,000 0,18646449 0,20281957 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,18646449 0,20272931 ! leukocyte migration GO:0050900 75 46 0,000 0,18646449 0,20263912 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,18646449 0,20254902 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,18646449 0,202459 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,18646449 0,20236906 ! pigmentation GO:0043473 103 46 0,000 0,18646449 0,2022792 ! cell growth GO:0016049 90 46 0,000 0,18646449 0,20218942 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,18646449 0,20209971 ! neural tube development GO:0021915 91 47 0,000 0,19010842 0,20595781 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,19010842 0,20586652 ! positive regulation of defense response GO:0031349 88 48 0,000 0,19373613 0,20970198 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,19373613 0,20960911 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,19373613 0,20951632 ! male sex differentiation GO:0046661 93 48 0,000 0,19373613 0,20942361 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,19373613 0,20933099 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,19373613 0,20923844 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,19734769 0,21304481 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,19734769 0,21295071 ! JNK cascade GO:0007254 106 49 0,000 0,19734769 0,21285669 ! protein homooligomerization GO:0051260 84 49 0,000 0,19734769 0,21276275 ! regulation of ion transport GO:0043269 86 50 0,000 0,20094317 0,21654352 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,20094317 0,21644805 ! endocrine system development GO:0035270 109 50 0,000 0,20094317 0,21635265 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,20094317 0,21625734 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,20094317 0,21616212 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,20094317 0,21606698 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,20094317 0,21597192 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,20452265 0,21972244 ! viral infectious cycle GO:0019058 104 51 0,000 0,20452265 0,21962586 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,20452265 0,21952937 ! peptide metabolic process GO:0006518 80 51 0,000 0,20452265 0,21943295 ! response to temperature stimulus GO:0009266 84 51 0,000 0,20452265 0,21933663 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,20452265 0,21924039 ! Notch signaling pathway GO:0007219 111 52 0,000 0,2080862 0,22296253 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,2080862 0,22286479 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,2080862 0,22276712 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,2080862 0,22266955 ! excretion GO:0007588 87 52 0,000 0,2080862 0,22257206 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,2080862 0,22247465 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,2080862 0,22237733 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,2080862 0,2222801 ! amino acid activation GO:0043038 98 52 0,000 0,2080862 0,22218295 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,21163388 0,22587224 ! vesicle organization GO:0016050 127 53 0,000 0,21163388 0,22577361 ! synapse organization GO:0050808 102 53 0,000 0,21163388 0,22567506 ! regulation of translational initiation GO:0006446 87 54 0,000 0,21516577 0,22934117 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,21516577 0,22924115 ! neuromuscular process GO:0050905 107 54 0,000 0,21516577 0,22914122 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,21516577 0,22904138 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,21516577 0,22894162 ! membrane fusion GO:0006944 122 54 0,000 0,21516577 0,22884195 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,21516577 0,22874237 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,21516577 0,22864287 ! RNA catabolic process GO:0006401 103 55 0,000 0,21868193 0,23227824 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,21868193 0,23217729 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,21868193 0,23207643 ! cell recognition GO:0008037 98 55 0,000 0,21868193 0,23197566 ! cell maturation GO:0048469 107 55 0,000 0,21868193 0,23187498 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,21868193 0,23177438 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,22218244 0,23538235 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,22218244 0,23528032 ! glucose catabolic process GO:0006007 88 56 0,000 0,22218244 0,23517838 ! RNA elongation GO:0006354 90 56 0,000 0,22218244 0,23507652 ! chloride transport GO:0006821 102 57 0,000 0,22566736 0,23866033 ! muscle fiber development GO:0048747 131 57 0,000 0,22566736 0,23855706 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,22566736 0,23845388 ! regulation of actin filament length GO:0030832 118 58 0,000 0,22913677 0,24201519 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,22913677 0,2419106 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,22913677 0,2418061 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,22913677 0,2417017 ! gastrulation GO:0007369 122 58 0,000 0,22913677 0,24159738 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,22913677 0,24149315 ! maintenance of location GO:0051235 124 58 0,000 0,22913677 0,24138902 ! nuclear export GO:0051168 110 59 0,000 0,23259073 0,24492205 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,23602931 0,24843585 ! kidney development GO:0001822 133 60 0,000 0,23602931 0,24832886 ! positive regulation of secretion GO:0051047 110 61 0,000 0,23945258 0,25182207 ! regulation of cellular component size GO:0032535 125 61 0,000 0,23945258 0,25171371 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,23945258 0,25160545 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,23945258 0,25149728 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,23945258 0,2513892 ! camera-type eye development GO:0043010 126 61 0,000 0,23945258 0,25128121 ! proton transport GO:0015992 117 61 0,000 0,23945258 0,25117332 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,24286061 0,25463883 ! tRNA processing GO:0008033 102 62 0,000 0,24286061 0,25452959 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,24625346 0,25797479 ! regulation of mitosis GO:0007088 112 63 0,000 0,24625346 0,25786421 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,24625346 0,25775373 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,24625346 0,25764334 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,24625346 0,25753305 ! hydrogen transport GO:0006818 121 64 0,000 0,24963121 0,2609538 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,24963121 0,26084219 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,24963121 0,26073067 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,25299391 0,26412996 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,25299391 0,26401714 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,25299391 0,2639044 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,25299391 0,26379177 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,25634163 0,26716835 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,25634163 0,26705442 ! gonad development GO:0008406 115 66 0,000 0,25634163 0,26694058 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,25967445 0,27029599 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,25967445 0,27018087 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,25967445 0,27006585 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,25967445 0,26995093 ! secondary metabolic process GO:0019748 125 67 0,000 0,25967445 0,2698361 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,26299242 0,27316773 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,26299242 0,27305163 ! hexose catabolic process GO:0019320 113 68 0,000 0,26299242 0,27293564 ! extracellular matrix organization GO:0030198 146 68 0,000 0,26299242 0,27281974 ! detection of external stimulus GO:0009581 102 68 0,000 0,26299242 0,27270394 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,26299242 0,27258824 ! cell projection assembly GO:0030031 138 68 0,000 0,26299242 0,27247264 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,26629562 0,27577796 ! urogenital system development GO:0001655 149 69 0,000 0,26629562 0,2756611 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,26629562 0,27554435 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,26629562 0,27542769 ! developmental maturation GO:0021700 128 69 0,000 0,26629562 0,27531113 ! single fertilization GO:0007338 83 69 0,000 0,26629562 0,27519467 ! cell redox homeostasis GO:0045454 114 70 0,000 0,26958411 0,27847525 ! germ cell development GO:0007281 133 70 0,000 0,26958411 0,27835755 ! activation of immune response GO:0002253 120 70 0,000 0,26958411 0,27823995 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,26958411 0,27812245 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,27285794 0,28138115 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,27285794 0,28126243 ! appendage morphogenesis GO:0035107 150 72 0,000 0,2761172 0,28450203 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,2761172 0,28438209 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,2761172 0,28426225 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,2761172 0,28414251 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,2761172 0,28402287 ! appendage development GO:0048736 151 73 0,000 0,27936194 0,28723957 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,27936194 0,28711873 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,27936194 0,28699799 ! regulation of immune effector process GO:0002697 156 73 0,000 0,27936194 0,28687735 ! acute inflammatory response GO:0002526 118 74 0,000 0,28259222 0,29007261 ! amino acid transport GO:0006865 148 74 0,000 0,28259222 0,28995078 ! transition metal ion transport GO:0000041 143 75 0,000 0,28580812 0,2931273 ! reproductive structure development GO:0048608 131 75 0,000 0,28580812 0,2930043 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,28580812 0,29288139 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,28580812 0,29275859 ! eye development GO:0001654 155 75 0,000 0,28580812 0,29263589 ! axon guidance GO:0007411 162 75 0,000 0,28580812 0,2925133 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,28900969 0,29566611 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,28900969 0,29554235 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,28900969 0,29541869 ! amine catabolic process GO:0009310 136 77 0,000 0,292197 0,29855176 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,292197 0,29842695 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,292197 0,29830224 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,29537011 0,30141569 ! antigen processing and presentation GO:0019882 117 78 0,000 0,29537011 0,30128984 ! fertilization GO:0009566 99 78 0,000 0,29537011 0,3011641 ! blood coagulation GO:0007596 151 79 0,000 0,29852908 0,30425805 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,29852908 0,30413117 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,29852908 0,3040044 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,30167398 0,30707897 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,30167398 0,30695108 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,30167398 0,30682329 ! muscle cell differentiation GO:0042692 178 81 0,000 0,30480487 0,30987861 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,30792181 0,31291721 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,31102486 0,31593918 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,31102486 0,31580787 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,31102486 0,31567667 ! inorganic anion transport GO:0015698 156 83 0,000 0,31102486 0,31554557 ! digestion GO:0007586 130 84 0,000 0,31411409 0,31854741 ! hemostasis GO:0007599 165 85 0,000 0,31718955 0,32153281 ! negative regulation of transport GO:0051051 164 85 0,000 0,31718955 0,32139945 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,31718955 0,3212662 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,31718955 0,32113306 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,31718955 0,32100003 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,32025131 0,32396437 ! regulation of lyase activity GO:0051339 169 86 0,000 0,32025131 0,32383027 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,32329942 0,3267772 ! alcohol catabolic process GO:0046164 142 87 0,000 0,32329942 0,32664205 ! regulation of protein transport GO:0051223 165 87 0,000 0,32329942 0,32650702 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,32633395 0,32943547 ! sensory perception of smell GO:0007608 117 88 0,000 0,32633395 0,3292994 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,32935496 0,33221064 ! cellular defense response GO:0006968 123 89 0,000 0,32935496 0,33207353 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,33236251 0,33496766 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,33535665 0,3378459 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 220 91 0,000 0,33535665 0,33770664 ! defense response to bacterium GO:0042742 112 91 0,000 0,33535665 0,33756749 ! amine transport GO:0015837 181 93 0,000 0,34130497 0,34341352 ! vitamin metabolic process GO:0006766 153 93 0,000 0,34130497 0,34327214 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,34425926 0,34610097 ! sterol metabolic process GO:0016125 166 94 0,000 0,34425926 0,3459586 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,34425926 0,34581635 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,34720038 0,34862742 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,34720038 0,34848419 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,34720038 0,34834108 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,34720038 0,34819808 ! sex differentiation GO:0007548 171 96 0,000 0,35012839 0,35099042 ! regulation of protein localization GO:0032880 188 97 0,000 0,35304335 0,3537674 ! forebrain development GO:0030900 210 98 0,000 0,35594532 0,35652908 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,35594532 0,35638296 ! mRNA transport GO:0051028 185 100 0,000 0,36171051 0,36200688 ! positive regulation of immune response GO:0050778 175 100 0,000 0,36171051 0,36185863 ! hormone metabolic process GO:0042445 171 100 0,000 0,36171051 0,36171051