pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1103-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 6,581E-07 1,608E-03 ! nuclear migration GO:0007097 13 6 2,000 9,485E-07 1,159E-03 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 9,485E-07 7,724E-04 GO:0031272|regulation of pseudopodium assembly, ! interphase of mitotic cell cycle GO:0051329 224 98 5,000 1,703E-06 1,04E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 3,000 2,036E-06 9,948E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 2,641E-06 1,076E-03 ! establishment of nucleus localization GO:0040023 18 8 2,000 2,641E-06 9,219E-04 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 2,809E-06 8,577E-04 ! regulation of fibroblast proliferation GO:0048145 56 28 3,000 3,267E-06 8,869E-04 ! macrophage differentiation GO:0030225 15 9 2,000 3,952E-06 9,654E-04 ! myeloid cell differentiation GO:0030099 126 67 4,000 4,877E-06 1,083E-03 ! metanephros development GO:0001656 81 32 3,000 5,674E-06 1,155E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 7,721E-06 1,451E-03 ! nucleus localization GO:0051647 22 11 2,000 7,721E-06 1,347E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 1,027E-05 1,672E-03 ! androgen receptor signaling pathway GO:0030521 81 37 3,000 1,027E-05 1,569E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 1,145E-05 1,646E-03 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 1,331E-05 1,807E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 2,697E-05 3,468E-03 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 2,982E-05 3,642E-03 ! filopodium assembly GO:0046847 42 17 2,000 3,131E-05 3,642E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 3,747E-05 4,161E-03 ! microspike assembly GO:0030035 46 18 2,000 3,747E-05 3,98E-03 ! G1 phase of mitotic cell cycle GO:0000080 39 19 2,000 4,438E-05 4,517E-03 ! response to UV GO:0009411 120 55 3,000 5,042E-05 4,927E-03 ! actin filament bundle formation GO:0051017 47 20 2,000 5,207E-05 4,893E-03 ! regulation of DNA replication GO:0006275 105 56 3,000 5,415E-05 4,899E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 6,059E-05 5,286E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 2,000 6,997E-05 5,894E-03 ! G1 phase GO:0051318 44 22 2,000 6,997E-05 5,698E-03 ! kidney development GO:0001822 133 60 3,000 7,108E-05 5,602E-03 ! DNA damage response, signal transduction GO:0042770 136 62 3,000 8,086E-05 6,173E-03 ! sex determination GO:0007530 48 24 2,000 9,147E-05 6,771E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 9,147E-05 6,572E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 9,158E-05 6,392E-03 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 9,158E-05 6,215E-03 ! regulation of lipid metabolic process GO:0019216 132 66 3,000 1,033E-04 6,82E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 1,033E-04 6,641E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 1,037E-04 6,493E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 1,037E-04 6,331E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 1,037E-04 6,177E-03 ! interaction with host GO:0051701 66 25 2,000 1,037E-04 6,03E-03 ! protein tetramerization GO:0051262 57 25 2,000 1,037E-04 5,889E-03 ! negative regulation of cell growth GO:0030308 142 67 3,000 1,095E-04 6,082E-03 ! negative regulation of cell size GO:0045792 144 69 3,000 1,229E-04 6,67E-03 ! urogenital system development GO:0001655 149 69 3,000 1,229E-04 6,525E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 1,311E-04 6,816E-03 ! 2-oxoglutarate metabolic process GO:0006103 10 5 1,000 1,318E-04 6,708E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 1,318E-04 6,571E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 1,318E-04 6,439E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,318E-04 6,313E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 1,318E-04 6,192E-03 ! G2/M transition checkpoint GO:0031576 8 5 1,000 1,318E-04 6,075E-03 GO:0031572|G2/M transition DNA damage checkpoint, ! protein insertion into membrane GO:0051205 17 5 1,000 1,318E-04 5,962E-03 ! cell cycle checkpoint GO:0000075 145 71 3,000 1,373E-04 6,099E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 3,000 1,373E-04 5,99E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 1,465E-04 6,278E-03 ! eye development GO:0001654 155 75 3,000 1,698E-04 7,153E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 1,806E-04 7,476E-03 ! positive regulation of DNA repair GO:0045739 9 6 1,000 1,972E-04 8,03E-03 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 1,972E-04 7,898E-03 ! glutamate catabolic process GO:0006538 12 6 1,000 1,972E-04 7,771E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,972E-04 7,647E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 1,972E-04 7,528E-03 ! neural tube patterning GO:0021532 8 6 1,000 1,972E-04 7,412E-03 ! negative regulation of oxidoreductase activity GO:0051354 11 6 1,000 1,972E-04 7,3E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 1,972E-04 7,191E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 1,972E-04 7,085E-03 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 1,000 1,972E-04 6,982E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 1,994E-04 6,958E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 2,633E-04 9,059E-03 ! negative regulation of growth GO:0045926 168 85 3,000 2,75E-04 9,333E-03 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 2,75E-04 9,205E-03 ! positive regulation of protein ubiquitination GO:0031398 14 7 1,000 2,754E-04 9,093E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 2,754E-04 8,972E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 2,754E-04 8,854E-03 ! oxaloacetate metabolic process GO:0006107 13 7 1,000 2,754E-04 8,739E-03 ! induction of apoptosis by oxidative stress GO:0008631 9 7 1,000 2,754E-04 8,627E-03 ! male sex determination GO:0030238 15 7 1,000 2,754E-04 8,517E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 2,754E-04 8,411E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,754E-04 8,307E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,754E-04 8,206E-03 ! aspartate family amino acid catabolic process GO:0009068 10 7 1,000 2,754E-04 8,107E-03 ! DNA damage checkpoint GO:0000077 78 35 2,000 2,872E-04 8,353E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 3,664E-04 0,0105297 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 3,664E-04 0,01040726 ! male meiosis GO:0007140 9 8 1,000 3,664E-04 0,01028764 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,664E-04 0,01017073 ! ER overload response GO:0006983 13 8 1,000 3,664E-04 0,01005645 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 3,664E-04 9,945E-03 ! response to tumor cell GO:0002347 16 8 1,000 3,664E-04 9,835E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 3,664E-04 9,729E-03 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 1,000 3,664E-04 9,624E-03 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 3,672E-04 9,544E-03 ! DNA integrity checkpoint GO:0031570 82 38 2,000 3,672E-04 9,444E-03 ! mitotic cell cycle checkpoint GO:0007093 76 39 2,000 3,968E-04 0,01009697 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 4,603E-04 0,01159395 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 4,699E-04 0,01171416 ! regulation of glycolysis GO:0006110 20 9 1,000 4,699E-04 0,01159583 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 4,699E-04 0,01147987 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 4,699E-04 0,01136621 ! postreplication repair GO:0006301 25 9 1,000 4,699E-04 0,01125478 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 4,699E-04 0,01114551 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 4,699E-04 0,01103834 ! leukocyte differentiation GO:0002521 232 98 3,000 4,731E-04 0,01100646 ! epithelial cell differentiation GO:0030855 83 43 2,000 5,301E-04 0,01221726 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 5,301E-04 0,01210308 ! double-strand break repair GO:0006302 85 44 2,000 5,674E-04 0,01283414 ! regulation of developmental growth GO:0048638 16 10 1,000 5,86E-04 0,01313345 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 5,86E-04 0,01301405 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 1,000 5,86E-04 0,01289681 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 5,86E-04 0,01278166 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 5,86E-04 0,01266855 ! epithelial cell development GO:0002064 21 10 1,000 5,86E-04 0,01255742 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 5,86E-04 0,01244822 ! protein heterooligomerization GO:0051291 17 10 1,000 5,86E-04 0,01234091 ! midbrain development GO:0030901 14 10 1,000 5,86E-04 0,01223543 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 5,86E-04 0,01213174 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 6,063E-04 0,01244655 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 6,469E-04 0,0131688 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 6,469E-04 0,01305997 ! thyroid gland development GO:0030878 26 11 1,000 7,145E-04 0,01430718 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 7,145E-04 0,01419086 ! regulation of intracellular pH GO:0051453 21 11 1,000 7,145E-04 0,01407642 ! regulation of embryonic development GO:0045995 35 11 1,000 7,145E-04 0,0139638 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 8,553E-04 0,01658377 ! virus-host interaction GO:0019048 30 12 1,000 8,553E-04 0,01645318 ! regulation of B cell proliferation GO:0030888 22 12 1,000 8,553E-04 0,01632464 ! focal adhesion formation GO:0048041 37 12 1,000 8,553E-04 0,0161981 ! entry into host cell GO:0030260 34 12 1,000 8,553E-04 0,0160735 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 8,553E-04 0,0159508 ! peptidyl-lysine modification GO:0018205 21 12 1,000 8,553E-04 0,01582996 ! localization within membrane GO:0051668 26 12 1,000 8,553E-04 0,01571094 ! regulation of cell projection organization GO:0031344 135 51 2,000 8,757E-04 0,01596432 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 1,008E-03 0,0182486 GO:0000725|recombinational repair, ! negative regulation of lipid metabolic process GO:0045833 20 13 1,000 1,008E-03 0,01811442 ! response to X-ray GO:0010165 28 13 1,000 1,008E-03 0,0179822 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 1,008E-03 0,01785189 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,008E-03 0,01772346 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of DNA repair GO:0006282 23 13 1,000 1,008E-03 0,01759686 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 1,008E-03 0,01747206 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 1,174E-03 0,02019208 GO:0060675|ureteric bud morphogenesis, ! regulation of cellular pH GO:0030641 27 14 1,000 1,174E-03 0,02005088 ! response to gamma radiation GO:0010332 30 14 1,000 1,174E-03 0,01991163 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 1,174E-03 0,01977431 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 1,211E-03 0,02026075 ! positive regulation of cell migration GO:0030335 137 58 2,000 1,273E-03 0,02116415 ! establishment of organelle localization GO:0051656 122 59 2,000 1,338E-03 0,02208845 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 1,351E-03 0,02215086 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 1,351E-03 0,02200319 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,351E-03 0,02185747 ! G1/S transition checkpoint GO:0031575 37 15 1,000 1,351E-03 0,02171367 ! camera-type eye development GO:0043010 126 61 2,000 1,474E-03 0,02352903 ! regulation of protein ubiquitination GO:0031396 28 16 1,000 1,54E-03 0,02443475 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,54E-03 0,02427711 ! glutamate metabolic process GO:0006536 25 16 1,000 1,54E-03 0,02412149 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 1,000 1,54E-03 0,02396785 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 1,000 1,54E-03 0,02381615 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,54E-03 0,02366636 ! viral reproductive process GO:0022415 132 62 2,000 1,544E-03 0,02358091 ! regulation of protein complex assembly GO:0043254 132 63 2,000 1,617E-03 0,02454084 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 1,741E-03 0,02626222 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 1,741E-03 0,0261011 ! positive regulation of cell motion GO:0051272 157 65 2,000 1,77E-03 0,02635937 ! centrosome cycle GO:0007098 26 18 1,000 1,955E-03 0,02893847 ! cell-substrate junction assembly GO:0007044 56 18 1,000 1,955E-03 0,02876414 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 1,955E-03 0,0285919 ! viral reproduction GO:0016032 142 68 2,000 2,014E-03 0,02928885 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 2,014E-03 0,02911554 ! cell projection assembly GO:0030031 138 68 2,000 2,014E-03 0,02894428 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 2,1E-03 0,03000319 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 2,1E-03 0,02982875 ! regulation of lipid biosynthetic process GO:0046890 28 19 1,000 2,179E-03 0,03077363 ! inositol metabolic process GO:0006020 33 19 1,000 2,179E-03 0,03059677 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 2,179E-03 0,03042193 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 2,179E-03 0,03024908 ! proximal/distal pattern formation GO:0009954 33 19 1,000 2,179E-03 0,03007818 ! negative regulation of kinase activity GO:0033673 145 70 2,000 2,188E-03 0,03003403 ! actin filament organization GO:0007015 167 72 2,000 2,372E-03 0,0323674 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 2,372E-03 0,03218758 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 2,372E-03 0,03200975 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 2,416E-03 0,0324244 ! protein amino acid acetylation GO:0006473 41 20 1,000 2,416E-03 0,03224722 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 2,416E-03 0,03207196 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 1,000 2,416E-03 0,0318986 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 2,416E-03 0,03172711 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 2,416E-03 0,03155744 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 2,416E-03 0,03138958 ! negative regulation of translation GO:0017148 32 20 1,000 2,416E-03 0,0312235 ! negative regulation of transferase activity GO:0051348 155 74 2,000 2,564E-03 0,03296861 ! organelle localization GO:0051640 155 74 2,000 2,564E-03 0,032796 ! lipid phosphorylation GO:0046834 43 21 1,000 2,663E-03 0,03388981 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 2,663E-03 0,03371422 ! regulation of transcription factor activity GO:0051090 137 75 2,000 2,664E-03 0,0335451 GO:0090046|regulation of transcription regulator activity, ! positive regulation of ligase activity GO:0051351 130 77 2,000 2,87E-03 0,03596188 ! cellular response to starvation GO:0009267 37 22 1,000 2,923E-03 0,0364308 ! ureteric bud development GO:0001657 50 22 1,000 2,923E-03 0,03624587 ! cell aging GO:0007569 48 22 1,000 2,923E-03 0,03606281 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 2,923E-03 0,03588159 ! positive regulation of B cell activation GO:0050871 42 22 1,000 2,923E-03 0,03570218 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 3,087E-03 0,03751672 ! protein oligomerization GO:0051259 149 79 2,000 3,087E-03 0,03733099 ! positive regulation of DNA replication GO:0045740 44 23 1,000 3,194E-03 0,03843255 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 3,194E-03 0,03824415 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 1,000 3,194E-03 0,03805759 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 3,194E-03 0,03787285 ! fatty acid transport GO:0015908 47 23 1,000 3,194E-03 0,03768989 ! protein import into nucleus GO:0006606 174 82 2,000 3,429E-03 0,04027922 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 3,476E-03 0,04062559 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 3,476E-03 0,04043214 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 3,476E-03 0,04024051 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 3,476E-03 0,0400507 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 3,476E-03 0,03986267 ! glutamine family amino acid catabolic process GO:0009065 45 24 1,000 3,476E-03 0,0396764 ! aspartate family amino acid metabolic process GO:0009066 47 24 1,000 3,476E-03 0,03949185 ! response to drug GO:0042493 149 83 2,000 3,549E-03 0,04013546 ! nuclear import GO:0051170 177 83 2,000 3,549E-03 0,0399505 ! T cell activation GO:0042110 189 84 2,000 3,67E-03 0,04113101 ! regulation of ligase activity GO:0051340 147 84 2,000 3,67E-03 0,0409432 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 3,769E-03 0,04185024 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 3,769E-03 0,04166088 ! vasculogenesis GO:0001570 49 25 1,000 3,769E-03 0,04147321 ! negative regulation of DNA replication GO:0008156 45 25 1,000 3,769E-03 0,04128724 ! initiation of viral infection GO:0019059 60 26 1,000 4,073E-03 0,04442194 ! microtubule organizing center organization GO:0031023 42 26 1,000 4,073E-03 0,04422451 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 4,073E-03 0,04402883 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 4,073E-03 0,04383487 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 4,073E-03 0,04364261 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 4,073E-03 0,04345203 ! negative regulation of cell development GO:0010721 83 26 1,000 4,073E-03 0,04326311 GO:0050768|negative regulation of neurogenesis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 4,073E-03 0,04307583 ! regulation of DNA binding GO:0051101 167 89 2,000 4,317E-03 0,04545792 ! protein localization in nucleus GO:0034504 192 89 2,000 4,317E-03 0,04526282 ! mitochondrial membrane organization GO:0007006 60 27 1,000 4,388E-03 0,04581594 ! response to starvation GO:0042594 47 27 1,000 4,388E-03 0,04562098 ! cellular response to nutrient levels GO:0031669 45 27 1,000 4,388E-03 0,04542767 ! regulation of cell cycle process GO:0010564 161 90 2,000 4,454E-03 0,04591169 ! protein amino acid acylation GO:0043543 59 28 1,000 4,715E-03 0,04839534 ! base-excision repair GO:0006284 41 28 1,000 4,715E-03 0,04819285 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 4,715E-03 0,04799205 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 4,881E-03 0,0494772 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 4,881E-03 0,04927275 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 5,052E-03 0,0507893 ! somitogenesis GO:0001756 52 29 1,000 5,052E-03 0,05058114 ! cell fate determination GO:0001709 64 30 1,000 5,4E-03 0,05384429 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 5,4E-03 0,05362541 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 1,000 5,4E-03 0,0534083 ! male gonad development GO:0008584 56 31 1,000 5,759E-03 0,05672598 ! erythrocyte differentiation GO:0030218 62 31 1,000 5,759E-03 0,05649817 ! cell junction assembly GO:0034329 85 31 1,000 5,759E-03 0,05627217 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 5,759E-03 0,05604798 ! spindle organization GO:0007051 50 32 1,000 6,128E-03 0,05940548 ! hindbrain development GO:0030902 65 32 1,000 6,128E-03 0,05917067 ! positive regulation of catabolic process GO:0009896 72 32 1,000 6,128E-03 0,05893772 ! regulation of pH GO:0006885 56 33 1,000 6,508E-03 0,06234534 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 6,508E-03 0,0621018 ! response to ionizing radiation GO:0010212 74 33 1,000 6,508E-03 0,06186016 ! leukocyte chemotaxis GO:0030595 55 33 1,000 6,508E-03 0,06162039 GO:0060326|cell chemotaxis, ! inner ear morphogenesis GO:0042472 51 34 1,000 6,898E-03 0,06506366 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 7,299E-03 0,06857795 ! calcium-mediated signaling GO:0019722 67 35 1,000 7,299E-03 0,0683152 ! negative regulation of DNA binding GO:0043392 67 36 1,000 7,709E-03 0,07188627 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 7,709E-03 0,07161294 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 8,131E-03 0,07523901 ! cell junction organization GO:0034330 96 37 1,000 8,131E-03 0,07495509 ! regulation of microtubule-based process GO:0032886 86 37 1,000 8,131E-03 0,07467331 ! negative regulation of binding GO:0051100 71 39 1,000 9,003E-03 0,08237829 ! carbohydrate homeostasis GO:0033500 59 39 1,000 9,003E-03 0,08207091 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 75 39 1,000 9,003E-03 0,08176582 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 9,003E-03 0,08146298 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 9,916E-03 0,08938912 ! gliogenesis GO:0042063 91 41 1,000 9,916E-03 0,08906049 ! ear morphogenesis GO:0042471 64 42 1,000 0,01038693 0,09294974 ! T cell differentiation GO:0030217 93 42 1,000 0,01038693 0,09261051 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,01038693 0,09227374 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01086776 0,09619538 GO:0090047|positive regulation of transcription regulator activity, ! glucose transport GO:0015758 66 43 1,000 0,01086776 0,09584811 ! monocarboxylic acid transport GO:0015718 93 43 1,000 0,01086776 0,09550333 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,01086776 0,09516103 ! segmentation GO:0035282 78 43 1,000 0,01086776 0,09482116 ! hexose transport GO:0008645 68 44 1,000 0,01135825 0,09874806 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,01185834 0,10273024 ! B cell differentiation GO:0030183 124 45 1,000 0,01185834 0,10236724 ! polyol metabolic process GO:0019751 77 45 1,000 0,01185834 0,10200679 ! leukocyte migration GO:0050900 75 46 1,000 0,01236795 0,10601724 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,01236795 0,10564655 ! pigmentation GO:0043473 103 46 1,000 0,01236795 0,10527844 ! neural tube development GO:0021915 91 47 1,000 0,01288701 0,10931589 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,01341545 0,11340461 ! mitochondrial transport GO:0006839 94 48 1,000 0,01341545 0,11301356 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01341545 0,1126252 ! male sex differentiation GO:0046661 93 48 1,000 0,01341545 0,1122395 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,01395317 0,11633994 ! endocrine system development GO:0035270 109 50 1,000 0,01450012 0,12048913 ! activation of caspase activity GO:0006919 95 50 1,000 0,01450012 0,12008069 ! regulation of ossification GO:0030278 123 50 1,000 0,01450012 0,11967502 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,01450012 0,11927207 ! viral infectious cycle GO:0019058 104 51 1,000 0,01505623 0,12343074 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,01505623 0,12301792 ! positive regulation of binding GO:0051099 88 52 1,000 0,0156214 0,12721029 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,0156214 0,12678767 ! cellular amino acid biosynthetic process GO:0008652 80 52 1,000 0,0156214 0,12636784 ! histone modification GO:0016570 104 52 1,000 0,0156214 0,12595078 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,0156214 0,12553647 ! positive regulation of growth GO:0045927 96 53 1,000 0,01619558 0,12972397 ! inner ear development GO:0048839 89 53 1,000 0,01619558 0,12930004 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,01619558 0,12887887 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,01619558 0,12846043 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,0167787 0,13265487 GO:0010863|positive regulation of phospholipase C activity, ! covalent chromatin modification GO:0016569 115 54 1,000 0,0167787 0,13222695 ! glutamine family amino acid metabolic process GO:0009064 85 54 1,000 0,0167787 0,13180178 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,0167787 0,13137934 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,01737067 0,13558001 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,01737067 0,13514822 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,01797143 0,1393784 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01815493 0,14035597 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01815493 0,13991321 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01815493 0,13947323 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01815493 0,13903601 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01815493 0,13860152 ! neuron fate determination GO:0048664 7 5 0,000 0,01815493 0,13816974 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01815493 0,13774064 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01815493 0,1373142 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01815493 0,13689039 ! polyol transport GO:0015791 12 5 0,000 0,01815493 0,13646919 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01815493 0,13605057 ! response to superoxide GO:0000303 10 5 0,000 0,01815493 0,13563452 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01815493 0,135221 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01815493 0,13480999 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01815493 0,13440148 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01815493 0,13399543 ! female meiosis GO:0007143 10 5 0,000 0,01815493 0,13359183 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01815493 0,13319065 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01815493 0,13279188 ! hypothalamus development GO:0021854 9 5 0,000 0,01815493 0,13239548 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01815493 0,13200145 ! cobalt ion transport GO:0006824 11 5 0,000 0,01815493 0,13160975 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01815493 0,13122038 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01815493 0,1308333 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01815493 0,13044849 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01815493 0,13006594 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01815493 0,12968564 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01815493 0,12930754 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01815493 0,12893165 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01815493 0,12855793 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01815493 0,12818638 ! transposition GO:0032196 9 5 0,000 0,01815493 0,12781697 ! negative chemotaxis GO:0050919 16 5 0,000 0,01815493 0,12744968 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01815493 0,12708449 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01815493 0,12672139 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01815493 0,12636036 ! behavioral response to pain GO:0048266 10 5 0,000 0,01815493 0,12600138 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01815493 0,12564444 ! Notch receptor processing GO:0007220 11 5 0,000 0,01815493 0,12528951 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01815493 0,12493658 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01815493 0,12458564 ! micturition GO:0060073 9 5 0,000 0,01815493 0,12423666 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01815493 0,12388963 ! copulation GO:0007620 9 5 0,000 0,01815493 0,12354453 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01815493 0,12320135 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01815493 0,12286008 ! bioluminescence GO:0008218 9 5 0,000 0,01815493 0,12252068 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01815493 0,12218316 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01815493 0,12184749 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01815493 0,12151366 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01815493 0,12118166 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01815493 0,12085146 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01815493 0,12052306 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01815493 0,12019644 ! grooming behavior GO:0007625 6 5 0,000 0,01815493 0,11987159 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01815493 0,11954848 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01815493 0,11922712 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01815493 0,11890747 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01815493 0,11858954 ! response to protozoan GO:0001562 13 5 0,000 0,01815493 0,1182733 ! lymph vessel development GO:0001945 10 5 0,000 0,01815493 0,11795874 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01815493 0,11764585 ! endochondral ossification GO:0001958 17 5 0,000 0,01815493 0,11733462 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01815493 0,11702503 ! single strand break repair GO:0000012 8 5 0,000 0,01815493 0,11671707 ! parathyroid gland development GO:0060017 14 5 0,000 0,01815493 0,11641073 ! anagen GO:0042640 7 5 0,000 0,01815493 0,11610599 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01815493 0,11580284 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01815493 0,11550127 ! cytokine secretion GO:0050663 15 5 0,000 0,01815493 0,11520127 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01815493 0,11490282 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01815493 0,11460591 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01815493 0,11431053 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01815493 0,11401668 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01815493 0,11372433 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01815493 0,11343347 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01815493 0,1131441 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01815493 0,1128562 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01815493 0,11256976 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01815493 0,11228478 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01815493 0,11200123 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01815493 0,11171911 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01815493 0,11143841 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01815493 0,11115912 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01815493 0,11088122 ! microvillus organization GO:0032528 8 5 0,000 0,01815493 0,11060471 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01815493 0,11032957 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01815493 0,1100558 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01815493 0,10978338 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01815493 0,10951231 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01815493 0,10924258 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01815493 0,10897417 ! polyol catabolic process GO:0046174 9 5 0,000 0,01815493 0,10870708 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01815493 0,10844129 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01815493 0,1081768 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01815493 0,10791359 ! muscle cell migration GO:0014812 8 5 0,000 0,01815493 0,10765167 ! mitochondrial fission GO:0000266 8 5 0,000 0,01815493 0,10739101 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01815493 0,10713161 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01815493 0,10687346 ! mRNA transcription GO:0009299 10 5 0,000 0,01815493 0,10661656 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01815493 0,10636088 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01815493 0,10610643 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01815493 0,10585319 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01815493 0,10560116 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01815493 0,10535033 ! monocyte activation GO:0042117 10 5 0,000 0,01815493 0,10510068 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01815493 0,10485222 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01815493 0,10460492 ! response to food GO:0032094 6 5 0,000 0,01815493 0,10435879 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01815493 0,10411382 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01815493 0,10386999 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01815493 0,10362731 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01815493 0,10338575 ! forebrain neuron development GO:0021884 13 5 0,000 0,01815493 0,10314532 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01815493 0,102906 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01815493 0,10266779 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01815493 0,10243069 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01815493 0,10219467 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01815493 0,10195974 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01815493 0,10172589 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01815493 0,10149311 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01815493 0,10126139 ! lipid glycosylation GO:0030259 7 5 0,000 0,01815493 0,10103072 ! nucleobase transport GO:0015851 6 5 0,000 0,01815493 0,10080111 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01815493 0,10057253 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01815493 0,10034499 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01815493 0,10011848 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01815493 0,09989299 ! basic amino acid transport GO:0015802 12 5 0,000 0,01815493 0,09966851 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01815493 0,09944504 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01815493 0,09922257 ! actin nucleation GO:0045010 11 5 0,000 0,01815493 0,09900109 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01815493 0,0987806 ! depurination GO:0045007 5 5 0,000 0,01815493 0,09856108 ! depyrimidination GO:0045008 10 5 0,000 0,01815493 0,09834254 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01815493 0,09812497 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01815493 0,09790836 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01815493 0,0976927 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01815493 0,09747799 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01815493 0,09726423 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01815493 0,09705139 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01815493 0,09683949 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01815493 0,09662851 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01815493 0,09641845 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01815493 0,0962093 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01815493 0,09600105 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01815493 0,09579371 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01815493 0,09558726 ! response to arsenic GO:0046685 11 5 0,000 0,01815493 0,09538169 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01815493 0,09517701 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01815493 0,09497321 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01815493 0,09477027 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01815493 0,0945682 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01815493 0,09436699 ! response to mercury ion GO:0046689 8 5 0,000 0,01815493 0,09416664 ! response to cadmium ion GO:0046686 7 5 0,000 0,01815493 0,09396713 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01815493 0,09376847 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01815493 0,09357065 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01815493 0,09337366 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01815493 0,09317749 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01815493 0,09298215 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01815493 0,09278763 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01815493 0,09259392 ! decidualization GO:0046697 11 5 0,000 0,01815493 0,09240102 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01815493 0,09220891 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01815493 0,09201761 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01815493 0,0918271 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01815493 0,09163737 ! embryonic cleavage GO:0040016 6 5 0,000 0,01815493 0,09144843 ! peroxisome fission GO:0016559 5 5 0,000 0,01815493 0,09126026 ! histone demethylation GO:0016577 13 5 0,000 0,01815493 0,09107287 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01815493 0,09088624 ! mitotic recombination GO:0006312 9 5 0,000 0,01815493 0,09070038 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01815493 0,09051528 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01815493 0,09033093 ! metaphase plate congression GO:0051310 7 5 0,000 0,01815493 0,09014733 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01815493 0,08996448 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01815493 0,08978236 ! enteric nervous system development GO:0048484 8 5 0,000 0,01815493 0,08960098 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01815493 0,08942034 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01815493 0,08924042 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01815493 0,08906122 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01815493 0,08888274 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01815493 0,08870497 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01815493 0,08852792 ! B cell homeostasis GO:0001782 13 5 0,000 0,01815493 0,08835157 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01815493 0,08817592 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01815493 0,08800097 ! metaphase GO:0051323 11 5 0,000 0,01815493 0,08782671 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01815493 0,08765314 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01815493 0,08748025 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01815493 0,08730805 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01815493 0,08713652 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01815493 0,08696566 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01815493 0,08679547 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01815493 0,08662595 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01815493 0,08645709 ! response to redox state GO:0051775 6 5 0,000 0,01815493 0,08628889 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01815493 0,08612133 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01815493 0,08595443 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01815493 0,08578818 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01815493 0,08562256 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01815493 0,08545759 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01815493 0,08529324 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01815493 0,08512953 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01815493 0,08496645 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01815493 0,08480399 ! striatum development GO:0021756 14 5 0,000 0,01815493 0,08464215 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01815493 0,08448093 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01815493 0,08432032 ! glial cell migration GO:0008347 10 5 0,000 0,01815493 0,08416032 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01815493 0,08400092 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01815493 0,08384213 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01815493 0,08368394 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01815493 0,08352634 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01815493 0,08336934 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01815493 0,08321292 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01815493 0,08305709 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01815493 0,08290185 ! neuroprotection GO:0043526 8 5 0,000 0,01815493 0,08274718 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01815493 0,08259309 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01815493 0,08243957 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01815493 0,08228662 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01815493 0,08213424 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01815493 0,08198242 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01815493 0,08183116 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01815493 0,08168046 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01815493 0,08153031 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01815493 0,08138071 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01815493 0,08123166 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01815493 0,08108316 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01815493 0,0809352 ! spindle assembly GO:0051225 6 5 0,000 0,01815493 0,08078777 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01815493 0,08064089 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01815493 0,08049453 ! protein palmitoylation GO:0018345 12 5 0,000 0,01815493 0,08034871 ! drug metabolic process GO:0017144 7 5 0,000 0,01815493 0,08020341 ! stem cell division GO:0017145 11 5 0,000 0,01815493 0,08005864 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01815493 0,07991439 ! organ regeneration GO:0031100 7 5 0,000 0,01815493 0,07977066 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01815493 0,07962745 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01815493 0,07948474 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,0185809 0,0812042 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,0185809 0,08105919 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,0185809 0,0809147 ! heart morphogenesis GO:0003007 105 57 1,000 0,0185809 0,08077072 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,0185809 0,08062726 ! aging GO:0007568 112 58 1,000 0,01919903 0,08316174 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,01919903 0,08301455 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,01919903 0,08286788 ! lipid modification GO:0030258 112 60 1,000 0,02046093 0,0881588 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,02110457 0,09077192 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02174647 0,09336841 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02174647 0,09320461 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02174647 0,09304138 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02174647 0,09287872 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02174647 0,09271663 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02174647 0,0925551 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02174647 0,09239414 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02174647 0,09223373 ! response to oxygen radical GO:0000305 11 6 0,000 0,02174647 0,09207388 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02174647 0,09191458 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02174647 0,09175583 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02174647 0,09159763 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02174647 0,09143998 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02174647 0,09128287 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02174647 0,09112629 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02174647 0,09097025 ! forebrain regionalization GO:0021871 9 6 0,000 0,02174647 0,09081475 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02174647 0,09065977 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02174647 0,09050533 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02174647 0,09035141 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02174647 0,09019801 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02174647 0,09004513 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02174647 0,08989277 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02174647 0,08974093 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02174647 0,08958959 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02174647 0,08943877 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02174647 0,08928845 ! malate metabolic process GO:0006108 13 6 0,000 0,02174647 0,08913864 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02174647 0,08898933 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02174647 0,08884051 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02174647 0,0886922 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02174647 0,08854438 ! protein refolding GO:0042026 15 6 0,000 0,02174647 0,08839705 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02174647 0,08825021 ! opsonization GO:0008228 8 6 0,000 0,02174647 0,08810386 ! mating behavior GO:0007617 7 6 0,000 0,02174647 0,08795799 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02174647 0,08781261 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02174647 0,0876677 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02174647 0,08752327 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02174647 0,08737932 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02174647 0,08723584 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02174647 0,08709283 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02174647 0,08695029 ! toxin metabolic process GO:0009404 11 6 0,000 0,02174647 0,08680822 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02174647 0,0866666 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02174647 0,08652545 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02174647 0,08638476 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02174647 0,08624453 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02174647 0,08610474 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02174647 0,08596542 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02174647 0,08582654 ! thymic T cell selection GO:0045061 16 6 0,000 0,02174647 0,08568811 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02174647 0,08555013 ! protein lipoylation GO:0009249 10 6 0,000 0,02174647 0,08541258 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02174647 0,08527549 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02174647 0,08513883 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02174647 0,0850026 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02174647 0,08486682 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02174647 0,08473146 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02174647 0,08459654 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02174647 0,08446205 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02174647 0,08432798 ! hyperosmotic response GO:0006972 10 6 0,000 0,02174647 0,08419434 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02174647 0,08406112 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02174647 0,08392832 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02174647 0,08379594 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02174647 0,08366398 ! urea metabolic process GO:0019627 7 6 0,000 0,02174647 0,08353243 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02174647 0,0834013 ! neutrophil activation GO:0042119 7 6 0,000 0,02174647 0,08327058 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02174647 0,08314026 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02174647 0,08301036 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02174647 0,08288085 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02174647 0,08275176 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02174647 0,08262306 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02174647 0,08249476 ! neuron apoptosis GO:0051402 15 6 0,000 0,02174647 0,08236686 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02174647 0,08223936 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02174647 0,08211225 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02174647 0,08198554 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02174647 0,08185921 ! carnitine transport GO:0015879 10 6 0,000 0,02174647 0,08173327 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02174647 0,08160772 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02174647 0,08148256 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02174647 0,08135778 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02174647 0,08123338 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02174647 0,08110936 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02174647 0,08098571 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02174647 0,08086245 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02174647 0,08073956 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02174647 0,08061704 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02174647 0,08049489 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02174647 0,08037311 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02174647 0,0802517 ! response to UV-C GO:0010225 14 6 0,000 0,02174647 0,08013066 ! astrocyte development GO:0014002 16 6 0,000 0,02174647 0,08000998 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02174647 0,07988967 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02174647 0,07976971 ! interaction with symbiont GO:0051702 14 6 0,000 0,02174647 0,07965012 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02174647 0,07953088 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02174647 0,079412 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02174647 0,07929347 ! response to copper ion GO:0046688 10 6 0,000 0,02174647 0,0791753 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02174647 0,07905748 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02174647 0,07894001 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02174647 0,07882289 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02174647 0,07870612 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02174647 0,07858969 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02174647 0,0784736 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02174647 0,07835786 ! hair follicle maturation GO:0048820 8 6 0,000 0,02174647 0,07824246 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02174647 0,07812739 ! Schwann cell development GO:0014044 15 6 0,000 0,02174647 0,07801267 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02174647 0,07789828 ! response to pheromone GO:0019236 6 6 0,000 0,02174647 0,07778423 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02174647 0,07767051 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02174647 0,07755712 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02174647 0,07744406 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02174647 0,07733134 ! subpallium development GO:0021544 15 6 0,000 0,02174647 0,07721894 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02174647 0,07710686 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02174647 0,07699511 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02174647 0,07688369 ! G2 phase GO:0051319 16 6 0,000 0,02174647 0,07677258 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02174647 0,0766618 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02174647 0,07655134 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02174647 0,07644119 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02174647 0,07633136 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02174647 0,07622185 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02174647 0,07611265 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02174647 0,07600376 ! receptor internalization GO:0031623 11 6 0,000 0,02174647 0,07589518 ! plasminogen activation GO:0031639 9 6 0,000 0,02174647 0,07578692 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02174647 0,07567896 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02174647 0,07557131 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02174647 0,07546396 ! protein deubiquitination GO:0016579 16 6 0,000 0,02174647 0,07535692 ! protein destabilization GO:0031648 9 6 0,000 0,02174647 0,07525018 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02174647 0,07514374 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02174647 0,07503761 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02174647 0,07493177 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02174647 0,07482624 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02174647 0,074721 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02174647 0,07461605 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02174647 0,0745114 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02174647 0,07440704 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02174647 0,07430298 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02174647 0,0741992 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02174647 0,07409571 ! neural plate development GO:0001840 9 6 0,000 0,02174647 0,07399252 ! catecholamine transport GO:0051937 9 6 0,000 0,02174647 0,07388961 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02174647 0,07378698 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02174647 0,07368464 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02174647 0,07358259 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02174647 0,07348081 ! maternal placenta development GO:0001893 12 6 0,000 0,02174647 0,07337932 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02174647 0,07327811 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02174647 0,07317717 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02174647 0,07307652 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02174647 0,07297614 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02174647 0,07287603 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02174647 0,0727762 GO:0055081|anion homeostasis, ! regulation of homeostatic process GO:0032844 148 62 1,000 0,02175657 0,0727104 ! regulation of mitosis GO:0007088 112 63 1,000 0,02241687 0,07481479 GO:0051783|regulation of nuclear division, ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,02308541 0,07694086 ! ear development GO:0043583 114 66 1,000 0,02444689 0,08136752 ! gonad development GO:0008406 115 66 1,000 0,02444689 0,08125681 ! activation of MAPK activity GO:0000187 124 67 1,000 0,02513971 0,08344607 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,02513971 0,08333284 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 1,000 0,02513971 0,08321992 ! tRNA transcription GO:0009304 17 7 0,000 0,02532498 0,08371978 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02532498 0,08360665 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02532498 0,08349382 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02532498 0,08338129 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02532498 0,08326907 ! sleep GO:0030431 16 7 0,000 0,02532498 0,08315715 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02532498 0,08304553 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02532498 0,08293421 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02532498 0,08282318 ! prostate gland development GO:0030850 14 7 0,000 0,02532498 0,08271246 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02532498 0,08260203 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02532498 0,08249189 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02532498 0,08238205 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02532498 0,0822725 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02532498 0,08216324 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02532498 0,08205427 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02532498 0,08194559 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02532498 0,08183719 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02532498 0,08172909 ! glycolipid transport GO:0046836 11 7 0,000 0,02532498 0,08162126 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02532498 0,08151373 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02532498 0,08140647 ! neuron adhesion GO:0007158 14 7 0,000 0,02532498 0,0812995 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02532498 0,08119281 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02532498 0,08108639 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02532498 0,08098026 ! mRNA stabilization GO:0048255 18 7 0,000 0,02532498 0,0808744 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02532498 0,08076882 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02532498 0,08066352 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02532498 0,08055849 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02532498 0,08045373 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02532498 0,08034925 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02532498 0,08024503 ! lipoprotein transport GO:0042953 14 7 0,000 0,02532498 0,08014109 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02532498 0,08003741 ! rhythmic behavior GO:0007622 17 7 0,000 0,02532498 0,079934 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02532498 0,07983086 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02532498 0,07972799 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02532498 0,07962538 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02532498 0,07952303 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02532498 0,07942095 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02532498 0,07931913 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02532498 0,07921757 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02532498 0,07911626 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02532498 0,07901522 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02532498 0,07891444 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02532498 0,07881391 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02532498 0,07871364 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02532498 0,07861362 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02532498 0,07851386 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02532498 0,07841435 ! spinal cord patterning GO:0021511 14 7 0,000 0,02532498 0,07831509 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02532498 0,07821608 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02532498 0,07811732 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02532498 0,07801881 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02532498 0,07792055 ! adrenal gland development GO:0030325 17 7 0,000 0,02532498 0,07782254 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02532498 0,07772477 ! ovulation GO:0030728 10 7 0,000 0,02532498 0,07762725 ! adenohypophysis development GO:0021984 11 7 0,000 0,02532498 0,07752997 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02532498 0,07743294 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02532498 0,07733615 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02532498 0,0772396 ! microtubule nucleation GO:0007020 21 7 0,000 0,02532498 0,07714329 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02532498 0,07704722 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02532498 0,07695139 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02532498 0,0768558 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02532498 0,07676044 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02532498 0,07666533 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02532498 0,07657044 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02532498 0,0764758 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02532498 0,07638138 ! galactose metabolic process GO:0006012 13 7 0,000 0,02532498 0,0762872 ! vesicle fusion GO:0006906 20 7 0,000 0,02532498 0,07619325 ! response to dietary excess GO:0002021 8 7 0,000 0,02532498 0,07609953 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02532498 0,07600604 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02532498 0,07591278 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02532498 0,07581975 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02532498 0,07572695 ! organ growth GO:0035265 15 7 0,000 0,02532498 0,07563437 ! nucleoside transport GO:0015858 11 7 0,000 0,02532498 0,07554203 ! nucleoside salvage GO:0043174 11 7 0,000 0,02532498 0,0754499 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02532498 0,075358 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02532498 0,07526632 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02532498 0,07517487 ! parturition GO:0007567 16 7 0,000 0,02532498 0,07508364 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02532498 0,07499263 ! rRNA modification GO:0000154 14 7 0,000 0,02532498 0,07490184 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02532498 0,07481127 ! spindle checkpoint GO:0031577 16 7 0,000 0,02532498 0,07472092 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02532498 0,07463078 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02532498 0,07454087 ! monocyte differentiation GO:0030224 16 7 0,000 0,02532498 0,07445117 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02532498 0,07436168 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02532498 0,07427241 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02532498 0,07418336 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02532498 0,07409451 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02532498 0,07400588 ! fibrinolysis GO:0042730 11 7 0,000 0,02532498 0,07391747 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02532498 0,07382926 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02532498 0,07374126 ! eating behavior GO:0042755 8 7 0,000 0,02532498 0,07365347 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02532498 0,0735659 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02532498 0,07347853 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02532498 0,07339136 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02532498 0,07330441 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02532498 0,07321766 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02532498 0,07313111 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02532498 0,07304477 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02532498 0,07295863 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02532498 0,0728727 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02532498 0,07278696 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02532498 0,07270143 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02532498 0,0726161 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02532498 0,07253097 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02532498 0,07244604 ! histone ubiquitination GO:0016574 9 7 0,000 0,02532498 0,07236131 ! regulation of meiosis GO:0040020 12 7 0,000 0,02532498 0,07227677 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02532498 0,07219244 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02532498 0,0721083 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02532498 0,07202435 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02532498 0,0719406 ! transcription termination GO:0006353 14 7 0,000 0,02532498 0,07185705 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02532498 0,07177369 ! anaphase GO:0051322 18 7 0,000 0,02532498 0,07169052 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02532498 0,07160754 ! axonal fasciculation GO:0007413 19 7 0,000 0,02532498 0,07152476 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02532498 0,07144217 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02532498 0,07135977 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02532498 0,07127756 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02532498 0,07119553 ! diuresis GO:0030146 12 7 0,000 0,02532498 0,0711137 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02532498 0,07103205 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02532498 0,07095059 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02532498 0,07086932 ! antibiotic transport GO:0042891 9 7 0,000 0,02532498 0,07078824 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02532498 0,07070734 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02532498 0,07062662 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02532498 0,07054609 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02532498 0,07046574 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02532498 0,07038557 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02532498 0,07030559 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02532498 0,07022579 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02532498 0,07014617 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02532498 0,07006673 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02532498 0,06998746 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02532498 0,06990838 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02532498 0,06982948 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02532498 0,06975075 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02532498 0,06967221 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02532498 0,06959383 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02532498 0,06951564 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02532498 0,06943762 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02532498 0,06935977 ! muscle adaptation GO:0043500 13 7 0,000 0,02532498 0,0692821 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02532498 0,06920461 ! retina homeostasis GO:0001895 12 7 0,000 0,02532498 0,06912728 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02532498 0,06905013 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02532498 0,06897315 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02532498 0,06889635 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02532498 0,06881971 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,02584048 0,07014255 ! regulation of lipase activity GO:0060191 137 68 1,000 0,02584048 0,0700647 ! lung development GO:0030324 165 69 1,000 0,02654915 0,0719064 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,02654915 0,07182677 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,02654915 0,07174732 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,02654915 0,07166804 ! germ cell development GO:0007281 133 70 1,000 0,02726565 0,07352094 ! appendage morphogenesis GO:0035107 150 72 1,000 0,02872185 0,07736217 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 1,000 0,02872185 0,07727697 ! respiratory tube development GO:0030323 171 72 1,000 0,02872185 0,07719196 ! B cell activation GO:0042113 179 72 1,000 0,02872185 0,07710713 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02889049 0,07747473 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02889049 0,07738978 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02889049 0,07730501 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02889049 0,07722043 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02889049 0,07713604 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02889049 0,07705183 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02889049 0,0769678 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02889049 0,07688396 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02889049 0,0768003 ! meiotic prophase I GO:0007128 14 8 0,000 0,02889049 0,07671682 ! response to zinc ion GO:0010043 12 8 0,000 0,02889049 0,07663352 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02889049 0,07655041 ! oligopeptide transport GO:0006857 16 8 0,000 0,02889049 0,07646747 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02889049 0,07638471 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02889049 0,07630214 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02889049 0,07621974 ! signal peptide processing GO:0006465 12 8 0,000 0,02889049 0,07613751 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02889049 0,07605547 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02889049 0,0759736 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02889049 0,07589191 ! succinate metabolic process GO:0006105 17 8 0,000 0,02889049 0,07581039 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02889049 0,07572905 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02889049 0,07564788 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02889049 0,07556689 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02889049 0,07548607 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02889049 0,07540542 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02889049 0,07532495 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02889049 0,07524464 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02889049 0,07516451 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02889049 0,07508455 ! reflex GO:0060004 17 8 0,000 0,02889049 0,07500476 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02889049 0,07492513 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02889049 0,07484568 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02889049 0,07476639 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02889049 0,07468728 ! pigment granule organization GO:0048753 17 8 0,000 0,02889049 0,07460832 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02889049 0,07452954 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02889049 0,07445092 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02889049 0,07437247 ! histidine catabolic process GO:0006548 10 8 0,000 0,02889049 0,07429418 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02889049 0,07421606 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02889049 0,0741381 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02889049 0,07406031 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02889049 0,07398268 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02889049 0,07390521 ! melanin metabolic process GO:0006582 17 8 0,000 0,02889049 0,0738279 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02889049 0,07375076 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02889049 0,07367377 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02889049 0,07359695 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02889049 0,07352029 ! macrophage activation GO:0042116 13 8 0,000 0,02889049 0,07344378 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02889049 0,07336744 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02889049 0,07329125 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02889049 0,07321522 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02889049 0,07313935 ! purine salvage GO:0043101 12 8 0,000 0,02889049 0,07306364 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02889049 0,07298808 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02889049 0,07291268 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02889049 0,07283744 ! osteoblast development GO:0002076 17 8 0,000 0,02889049 0,07276235 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02889049 0,07268741 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02889049 0,07261263 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02889049 0,072538 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02889049 0,07246353 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02889049 0,07238921 ! response to UV-B GO:0010224 17 8 0,000 0,02889049 0,07231504 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02889049 0,07224102 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02889049 0,07216715 ! intermediate filament organization GO:0045109 12 8 0,000 0,02889049 0,07209344 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02889049 0,07201987 ! cellular extravasation GO:0045123 13 8 0,000 0,02889049 0,07194646 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02889049 0,07187319 ! response to antibiotic GO:0046677 11 8 0,000 0,02889049 0,07180008 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02889049 0,07172711 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02889049 0,07165429 ! DNA topological change GO:0006265 12 8 0,000 0,02889049 0,07158162 ! response to tropane GO:0014073 15 8 0,000 0,02889049 0,07150909 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02889049 0,07143672 ! melanosome transport GO:0032402 13 8 0,000 0,02889049 0,07136448 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02889049 0,0712924 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02889049 0,07122046 ! mast cell activation GO:0045576 14 8 0,000 0,02889049 0,07114866 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02889049 0,07107701 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02889049 0,07100551 ! gas homeostasis GO:0033483 14 8 0,000 0,02889049 0,07093415 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02889049 0,07086293 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02889049 0,07079185 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02889049 0,07072092 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02889049 0,07065013 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02889049 0,07057947 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02889049 0,07050897 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02889049 0,0704386 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02889049 0,07036837 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02889049 0,07029828 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02889049 0,07022833 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02889049 0,07015852 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02889049 0,07008885 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02889049 0,07001932 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02889049 0,06994993 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02889049 0,06988067 ! hormone catabolic process GO:0042447 17 8 0,000 0,02889049 0,06981155 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02889049 0,06974256 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02889049 0,06967372 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02889049 0,069605 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02889049 0,06953643 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02889049 0,06946799 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02889049 0,06939968 ! adult feeding behavior GO:0008343 10 8 0,000 0,02889049 0,06933151 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02889049 0,06926347 ! ATP catabolic process GO:0006200 11 8 0,000 0,02889049 0,06919556 ! blastocyst growth GO:0001832 19 8 0,000 0,02889049 0,06912779 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02889049 0,06906015 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02889049 0,06899264 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02889049 0,06892527 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02889049 0,06885802 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02889049 0,06879091 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02889049 0,06872393 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02889049 0,06865708 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02889049 0,06859035 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02889049 0,06852376 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02889049 0,0684573 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02889049 0,06839096 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02889049 0,06832476 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02889049 0,06825868 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02889049 0,06819273 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02889049 0,06812691 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02889049 0,06806121 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02889049 0,06799564 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02889049 0,0679302 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02889049 0,06786488 ! appendage development GO:0048736 151 73 1,000 0,02946144 0,06913957 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 0,03020859 0,07082493 ! respiratory system development GO:0060541 175 74 1,000 0,03020859 0,07075702 ! reproductive structure development GO:0048608 131 75 1,000 0,03096324 0,07245516 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,03096324 0,07238582 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,03172532 0,07409653 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,03172532 0,07402576 ! axon extension GO:0048675 16 9 0,000 0,03244307 0,07562825 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03244307 0,07555616 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03244307 0,0754842 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03244307 0,07541238 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03244307 0,07534069 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03244307 0,07526915 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03244307 0,07519773 ! reproductive behavior GO:0019098 22 9 0,000 0,03244307 0,07512646 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03244307 0,07505531 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03244307 0,07498431 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03244307 0,07491343 ! UTP metabolic process GO:0046051 10 9 0,000 0,03244307 0,07484269 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03244307 0,07477209 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,03244307 0,07470161 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03244307 0,07463127 ! artery development GO:0060840 25 9 0,000 0,03244307 0,07456106 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03244307 0,07449099 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03244307 0,07442104 ! equilibrioception GO:0050957 20 9 0,000 0,03244307 0,07435123 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03244307 0,07428155 ! chemosensory behavior GO:0007635 21 9 0,000 0,03244307 0,074212 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03244307 0,07414257 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03244307 0,07407328 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03244307 0,07400412 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03244307 0,07393508 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03244307 0,07386618 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03244307 0,0737974 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03244307 0,07372875 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03244307 0,07366023 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03244307 0,07359184 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03244307 0,07352357 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03244307 0,07345543 ! protein targeting to ER GO:0045047 25 9 0,000 0,03244307 0,07338742 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03244307 0,07331953 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,03244307 0,07325177 ! T cell selection GO:0045058 27 9 0,000 0,03244307 0,07318413 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03244307 0,07311662 ! glycine catabolic process GO:0006546 15 9 0,000 0,03244307 0,07304923 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03244307 0,07298196 ! endosome organization GO:0007032 20 9 0,000 0,03244307 0,07291482 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03244307 0,0728478 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03244307 0,07278091 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03244307 0,07271414 ! mannose metabolic process GO:0006013 13 9 0,000 0,03244307 0,07264749 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03244307 0,07258096 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03244307 0,07251456 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03244307 0,07244827 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03244307 0,07238211 ! receptor clustering GO:0043113 20 9 0,000 0,03244307 0,07231607 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03244307 0,07225015 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03244307 0,07218435 ! retinol metabolic process GO:0042572 20 9 0,000 0,03244307 0,07211866 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03244307 0,0720531 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03244307 0,07198766 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03244307 0,07192233 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03244307 0,07185713 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03244307 0,07179204 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03244307 0,07172707 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03244307 0,07166222 ! response to amine stimulus GO:0014075 13 9 0,000 0,03244307 0,07159748 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03244307 0,07153286 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03244307 0,07146836 ! erythrocyte development GO:0048821 17 9 0,000 0,03244307 0,07140397 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03244307 0,0713397 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03244307 0,07127555 ! renal water homeostasis GO:0003091 15 9 0,000 0,03244307 0,07121151 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03244307 0,07114759 ! icosanoid secretion GO:0032309 15 9 0,000 0,03244307 0,07108378 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03244307 0,07102008 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03244307 0,0709565 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03244307 0,07089303 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03244307 0,07082968 ! sterol catabolic process GO:0016127 14 9 0,000 0,03244307 0,07076644 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03244307 0,07070331 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03244307 0,07064029 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03244307 0,07057739 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03244307 0,0705146 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03244307 0,07045192 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03244307 0,07038935 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03244307 0,0703269 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03244307 0,07026455 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03244307 0,07020231 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03244307 0,07014019 ! purine base metabolic process GO:0006144 25 9 0,000 0,03244307 0,07007817 ! pigment granule transport GO:0051904 17 9 0,000 0,03244307 0,07001626 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,03244307 0,06995447 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03244307 0,06989278 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03244307 0,0698312 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03244307 0,06976973 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03244307 0,06970836 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03244307 0,06964711 ! mitochondrion localization GO:0051646 18 9 0,000 0,03244307 0,06958596 ! amine catabolic process GO:0009310 136 77 1,000 0,03249479 0,06963576 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,03249479 0,06957473 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,03249479 0,0695138 ! regulation of catabolic process GO:0009894 173 77 1,000 0,03249479 0,06945299 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,03327156 0,07105107 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,03405558 0,07266182 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,03484679 0,07428509 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,03484679 0,07422032 ! meiosis GO:0007126 143 81 1,000 0,03564512 0,07585456 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 1,000 0,03564512 0,07578854 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,03564512 0,07572264 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03598274 0,07637345 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03598274 0,07630715 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03598274 0,07624097 ! associative learning GO:0008306 21 10 0,000 0,03598274 0,07617491 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03598274 0,07610895 ! phosphate transport GO:0006817 24 10 0,000 0,03598274 0,07604311 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03598274 0,07597739 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03598274 0,07591178 ! CTP metabolic process GO:0046036 11 10 0,000 0,03598274 0,07584628 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,03598274 0,0757809 ! GTP metabolic process GO:0046039 11 10 0,000 0,03598274 0,07571562 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03598274 0,07565047 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03598274 0,07558542 ! social behavior GO:0035176 29 10 0,000 0,03598274 0,07552048 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03598274 0,07545566 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03598274 0,07539094 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03598274 0,07532634 ! androgen metabolic process GO:0008209 17 10 0,000 0,03598274 0,07526185 ! phospholipid efflux GO:0033700 19 10 0,000 0,03598274 0,07519747 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03598274 0,0751332 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03598274 0,07506904 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03598274 0,07500498 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03598274 0,07494104 ! lung alveolus development GO:0048286 26 10 0,000 0,03598274 0,07487721 ! pathogenesis GO:0009405 17 10 0,000 0,03598274 0,07481348 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03598274 0,07474986 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03598274 0,07468636 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03598274 0,07462295 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,03598274 0,07455966 ! endoderm development GO:0007492 18 10 0,000 0,03598274 0,07449647 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03598274 0,0744334 ! arginine catabolic process GO:0006527 17 10 0,000 0,03598274 0,07437042 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03598274 0,07430756 ! proline metabolic process GO:0006560 13 10 0,000 0,03598274 0,0742448 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03598274 0,07418214 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03598274 0,0741196 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03598274 0,07405715 ! V(D)J recombination GO:0033151 34 10 0,000 0,03598274 0,07399482 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03598274 0,07393258 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03598274 0,07387045 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03598274 0,07380843 ! B cell proliferation GO:0042100 19 10 0,000 0,03598274 0,07374651 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03598274 0,07368469 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03598274 0,07362298 ! multicellular organism growth GO:0035264 19 10 0,000 0,03598274 0,07356137 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03598274 0,07349987 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03598274 0,07343846 ! ruffle organization GO:0031529 17 10 0,000 0,03598274 0,07337716 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03598274 0,07331596 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03598274 0,07325487 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03598274 0,07319387 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03598274 0,07313298 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03598274 0,07307219 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03598274 0,0730115 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,03598274 0,0729509 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03598274 0,07289041 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03598274 0,07283003 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03598274 0,07276974 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03598274 0,07270955 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03598274 0,07264945 ! segment specification GO:0007379 15 10 0,000 0,03598274 0,07258946 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,03598274 0,07252957 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,03598274 0,07246978 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03598274 0,07241008 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03598274 0,07235049 ! response to dsRNA GO:0043331 23 10 0,000 0,03598274 0,07229099 ! DNA ligation GO:0006266 18 10 0,000 0,03598274 0,07223159 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03598274 0,07217228 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03598274 0,07211308 ! melanosome localization GO:0032400 16 10 0,000 0,03598274 0,07205397 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03598274 0,07199496 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03598274 0,07193604 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03598274 0,07187722 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03598274 0,0718185 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03598274 0,07175987 ! induction of an organ GO:0001759 17 10 0,000 0,03598274 0,07170134 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03598274 0,0716429 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03598274 0,07158456 ! protein sumoylation GO:0016925 17 10 0,000 0,03598274 0,07152631 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03598274 0,07146816 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03598274 0,07141011 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03598274 0,07135214 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03598274 0,07129427 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03598274 0,0712365 ! salivary gland development GO:0007431 28 10 0,000 0,03598274 0,07117882 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03598274 0,07112123 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03598274 0,07106374 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03598274 0,07100633 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03598274 0,07094902 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03598274 0,07089181 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,03598274 0,07083468 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03598274 0,07077765 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03598274 0,07072071 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03598274 0,07066386 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03598274 0,0706071 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03598274 0,07055043 ! detection of calcium ion GO:0005513 24 10 0,000 0,03598274 0,07049386 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03598274 0,07043737 ! blastocyst formation GO:0001825 18 10 0,000 0,03598274 0,07038098 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03598274 0,07032467 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03598274 0,07026846 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03598274 0,07021233 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03598274 0,0701563 ! response to nicotine GO:0035094 20 10 0,000 0,03598274 0,07010035 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03598274 0,07004449 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03598274 0,06998873 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,03645051 0,07084217 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,03645051 0,07078585 ! meiotic cell cycle GO:0051321 144 82 1,000 0,03645051 0,07072963 ! response to oxygen levels GO:0070482 183 83 1,000 0,03726291 0,07224863 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,03726291 0,07219134 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,03726291 0,07213414 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,03950957 0,07642271 ! respiratory burst GO:0045730 17 11 0,000 0,03950957 0,07636224 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,03950957 0,07630188 ! neuron fate specification GO:0048665 18 11 0,000 0,03950957 0,07624161 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03950957 0,07618143 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,03950957 0,07612135 ! synapsis GO:0007129 14 11 0,000 0,03950957 0,07606137 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03950957 0,07600148 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,03950957 0,07594168 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,03950957 0,07588198 ! response to pain GO:0048265 27 11 0,000 0,03950957 0,07582237 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03950957 0,07576285 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,03950957 0,07570343 ! blood vessel remodeling GO:0001974 30 11 0,000 0,03950957 0,0756441 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,03950957 0,07558487 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,03950957 0,07552573 ! bone resorption GO:0045453 16 11 0,000 0,03950957 0,07546667 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03950957 0,07540772 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03950957 0,07534885 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03950957 0,07529008 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03950957 0,07523139 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03950957 0,0751728 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03950957 0,0751143 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,03950957 0,07505589 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,03950957 0,07499757 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03950957 0,07493935 ! UV protection GO:0009650 20 11 0,000 0,03950957 0,07488121 ! adult heart development GO:0007512 16 11 0,000 0,03950957 0,07482316 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,03950957 0,0747652 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03950957 0,07470734 ! macroautophagy GO:0016236 19 11 0,000 0,03950957 0,07464956 ! temperature homeostasis GO:0001659 18 11 0,000 0,03950957 0,07459187 ! behavioral fear response GO:0001662 27 11 0,000 0,03950957 0,07453427 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03950957 0,07447676 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03950957 0,07441933 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,03950957 0,074362 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,03950957 0,07430476 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,03950957 0,0742476 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03950957 0,07419053 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,03950957 0,07413355 ! regulation of organ growth GO:0046620 14 11 0,000 0,03950957 0,07407665 ! pigment granule localization GO:0051875 20 11 0,000 0,03950957 0,07401984 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03950957 0,07396312 ! vasoconstriction GO:0042310 20 11 0,000 0,03950957 0,07390649 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,03950957 0,07384994 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03950957 0,07379348 ! embryonic axis specification GO:0000578 19 11 0,000 0,03950957 0,07373711 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03950957 0,07368082 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03950957 0,07362462 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03950957 0,0735685 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03950957 0,07351247 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03950957 0,07345653 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03950957 0,07340067 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03950957 0,07334489 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,03950957 0,0732892 ! prophase GO:0051324 17 11 0,000 0,03950957 0,07323359 ! neuroblast proliferation GO:0007405 25 11 0,000 0,03950957 0,07317807 ! nucleosome positioning GO:0016584 15 11 0,000 0,03950957 0,07312263 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03950957 0,07306728 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03950957 0,07301201 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03950957 0,07295682 ! apical protein localization GO:0045176 18 11 0,000 0,03950957 0,07290172 ! acid secretion GO:0046717 20 11 0,000 0,03950957 0,0728467 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03950957 0,07279176 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03950957 0,07273691 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,03950957 0,07268214 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03950957 0,07262745 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03950957 0,07257284 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,03950957 0,07251831 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,03950957 0,07246387 ! cholesterol efflux GO:0033344 21 11 0,000 0,03950957 0,07240951 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03950957 0,07235523 ! oocyte development GO:0048599 20 11 0,000 0,03950957 0,07230103 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,03950957 0,07224691 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,03950957 0,07219288 ! embryonic gut development GO:0048566 19 11 0,000 0,03950957 0,07213892 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03950957 0,07208505 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,03950957 0,07203125 ! activation of innate immune response GO:0002218 16 11 0,000 0,03950957 0,07197754 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03950957 0,0719239 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,03950957 0,07187035 ! lysogeny GO:0030069 22 11 0,000 0,03950957 0,07181687 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03950957 0,07176348 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,03950957 0,07171016 ! sequestering of metal ion GO:0051238 15 11 0,000 0,03950957 0,07165692 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,03974148 0,07202405 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 159 87 1,000 0,04058126 0,07349149 ! amine biosynthetic process GO:0009309 146 88 1,000 0,04142774 0,07496887 ! tube morphogenesis GO:0035239 194 89 1,000 0,04228087 0,07645608 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,04302359 0,07774159 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,04302359 0,07768413 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,04302359 0,07762676 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,04302359 0,07756947 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04302359 0,07751227 ! protein complex disassembly GO:0043241 28 12 0,000 0,04302359 0,07745515 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04302359 0,07739811 ! hippocampus development GO:0021766 29 12 0,000 0,04302359 0,07734116 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,04302359 0,07728429 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,04302359 0,0772275 ! T cell proliferation GO:0042098 32 12 0,000 0,04302359 0,0771708 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04302359 0,07711418 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,04302359 0,07705765 ! ventral spinal cord development GO:0021517 25 12 0,000 0,04302359 0,0770012 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,04302359 0,07694483 ! drug transport GO:0015893 16 12 0,000 0,04302359 0,07688854 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,04302359 0,07683233 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,04302359 0,07677621 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,04302359 0,07672017 ! polyamine metabolic process GO:0006595 18 12 0,000 0,04302359 0,07666421 ! mitotic spindle organization GO:0007052 23 12 0,000 0,04302359 0,07660833 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,04302359 0,07655254 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,04302359 0,07649682 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,04302359 0,07644119 ! lipid digestion GO:0044241 21 12 0,000 0,04302359 0,07638563 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,04302359 0,07633016 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04302359 0,07627477 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,04302359 0,07621946 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,04302359 0,07616423 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04302359 0,07610908 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,04302359 0,076054 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,04302359 0,07599901 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,04302359 0,0759441 ! snRNA metabolic process GO:0016073 30 12 0,000 0,04302359 0,07588927 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,04302359 0,07583451 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,04302359 0,07577984 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04302359 0,07572524 ! cranial nerve development GO:0021545 23 12 0,000 0,04302359 0,07567072 ! fucose catabolic process GO:0019317 25 12 0,000 0,04302359 0,07561628 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,04302359 0,07556192 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,04302359 0,07550764 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04302359 0,07545343 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,04302359 0,07539931 ! zymogen activation GO:0031638 18 12 0,000 0,04302359 0,07534526 ! T cell homeostasis GO:0043029 28 12 0,000 0,04302359 0,07529128 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,04302359 0,07523739 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,04302359 0,07518357 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,04302359 0,07512983 ! oocyte differentiation GO:0009994 21 12 0,000 0,04302359 0,07507617 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,04302359 0,07502258 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,04302359 0,07496907 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,04302359 0,07491563 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,04302359 0,07486227 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,04302359 0,07480899 ! defense response to fungus GO:0050832 15 12 0,000 0,04302359 0,07475578 ! developmental induction GO:0031128 22 12 0,000 0,04302359 0,07470265 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,04302359 0,0746496 ! lamellipodium assembly GO:0030032 24 12 0,000 0,04302359 0,07459662 ! response to cold GO:0009409 17 12 0,000 0,04302359 0,07454371 ! establishment of cell polarity GO:0030010 21 12 0,000 0,04302359 0,07449088 ! regulation of synapse organization GO:0050807 18 12 0,000 0,04302359 0,07443813 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,04314057 0,07458769 ! ossification GO:0001503 205 91 1,000 0,04400679 0,07603154 ! gland development GO:0048732 220 91 1,000 0,04400679 0,0759778 ! bone development GO:0060348 206 92 1,000 0,04487948 0,07742978 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,04487948 0,07737513 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,04652486 0,08015531 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04652486 0,08009882 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,04652486 0,08004241 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04652486 0,07998608 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,04652486 0,07992983 ! peroxisomal transport GO:0043574 28 13 0,000 0,04652486 0,07987366 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,04652486 0,07981757 ! cartilage condensation GO:0001502 22 13 0,000 0,04652486 0,07976156 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,04652486 0,07970563 ! organelle fusion GO:0048284 36 13 0,000 0,04652486 0,07964977 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,04652486 0,07959399 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,04652486 0,07953829 ! endocrine pancreas development GO:0031018 25 13 0,000 0,04652486 0,07948267 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,04652486 0,07942713 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,04652486 0,07937166 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,04652486 0,07931628 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,04652486 0,07926096 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,04652486 0,07920573 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04652486 0,07915057 ! methionine metabolic process GO:0006555 31 13 0,000 0,04652486 0,07909549 ! plasma membrane organization GO:0007009 27 13 0,000 0,04652486 0,07904049 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,04652486 0,07898556 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,04652486 0,07893071 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,04652486 0,07887594 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,04652486 0,07882124 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,04652486 0,07876661 ! exocrine system development GO:0035272 34 13 0,000 0,04652486 0,07871207 ! asymmetric protein localization GO:0008105 24 13 0,000 0,04652486 0,07865759 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,04652486 0,0786032 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,04652486 0,07854888 ! L-glutamate transport GO:0015813 30 13 0,000 0,04652486 0,07849463 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,04652486 0,07844046 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,04652486 0,07838636 ! protein homotetramerization GO:0051289 24 13 0,000 0,04652486 0,07833234 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,04652486 0,07827839 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,04652486 0,07822452 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,04652486 0,07817072 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,04652486 0,07811699 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04652486 0,07806334 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,04652486 0,07800976 ! histone methylation GO:0016571 29 13 0,000 0,04652486 0,07795626 ! chromatin silencing GO:0006342 29 13 0,000 0,04652486 0,07790283 ! gland morphogenesis GO:0022612 31 13 0,000 0,04652486 0,07784947 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,04652486 0,07779618 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04652486 0,07774297 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,04652486 0,07768983 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,04652486 0,07763676 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,04652486 0,07758377 ! spleen development GO:0048536 24 13 0,000 0,04652486 0,07753085 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,04652486 0,077478 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,04652486 0,07742522 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,04652486 0,07737251 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,04652486 0,07731988 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,04652486 0,07726732 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04652486 0,07721483 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,04652486 0,07716241 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,04652486 0,07711006 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,04652486 0,07705778 ! insulin secretion GO:0030073 24 13 0,000 0,04652486 0,07700557 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,04652486 0,07695343 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,04652486 0,07690137 ! acrosome reaction GO:0007340 19 13 0,000 0,04652486 0,07684937 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,04652486 0,07679745 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,04652486 0,07674559 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,046644 0,07689022 ! sex differentiation GO:0007548 171 96 1,000 0,04843369 0,07978658 ! rRNA transcription GO:0009303 28 14 0,000 0,05001341 0,08233339 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,05001341 0,08227795 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,05001341 0,08222258 ! water transport GO:0006833 21 14 0,000 0,05001341 0,08216729 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,05001341 0,08211207 ! non-recombinational repair GO:0000726 29 14 0,000 0,05001341 0,08205692 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,05001341 0,08200185 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,05001341 0,08194685 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,05001341 0,08189193 ! RNA polyadenylation GO:0043631 32 14 0,000 0,05001341 0,08183708 ! lipid localization GO:0010876 32 14 0,000 0,05001341 0,0817823 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,05001341 0,0817276 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,05001341 0,08167297 ! regulated secretory pathway GO:0045055 24 14 0,000 0,05001341 0,08161841 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,05001341 0,08156392 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,05001341 0,08150951 ! arginine metabolic process GO:0006525 21 14 0,000 0,05001341 0,08145517 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,05001341 0,0814009 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,05001341 0,08134671 ! regulation of heart rate GO:0002027 25 14 0,000 0,05001341 0,08129259 ! fear response GO:0042596 34 14 0,000 0,05001341 0,08123854 ! organic alcohol transport GO:0015850 29 14 0,000 0,05001341 0,08118456 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,05001341 0,08113065 ! embryo implantation GO:0007566 30 14 0,000 0,05001341 0,08107681 ! neutral amino acid transport GO:0015804 28 14 0,000 0,05001341 0,08102305 ! bone mineralization GO:0030282 18 14 0,000 0,05001341 0,08096936 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,05001341 0,08091573 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,05001341 0,08086218 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,05001341 0,0808087 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,05001341 0,08075529 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,05001341 0,08070195 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,05001341 0,08064868 ! ribosome assembly GO:0042255 18 14 0,000 0,05001341 0,08059549 ! cerebellum development GO:0021549 23 14 0,000 0,05001341 0,08054236 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,05001341 0,0804893 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,05001341 0,08043631 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,05001341 0,08038339 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,05001341 0,08033054 ! NADP metabolic process GO:0006739 24 14 0,000 0,05001341 0,08027776 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,05001341 0,08022505 ! oxygen transport GO:0015671 22 14 0,000 0,05001341 0,08017241 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05001341 0,08011984 ! male genitalia development GO:0030539 26 14 0,000 0,05001341 0,08006734 ! regulation of RNA stability GO:0043487 33 14 0,000 0,05001341 0,0800149 ! regulation of axon extension GO:0030516 43 14 0,000 0,05001341 0,07996254 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,05001341 0,07991024 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,05001341 0,07985801 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,05208672 0,0831142 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 1,000 0,05208672 0,08305995 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0534893 0,08524093 ! lactation GO:0007595 30 15 0,000 0,0534893 0,08518536 ! reproductive cellular process GO:0048610 22 15 0,000 0,0534893 0,08512987 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0534893 0,08507445 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,0534893 0,08501909 ! superoxide anion generation GO:0042554 22 15 0,000 0,0534893 0,08496382 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,0534893 0,08490861 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,0534893 0,08485347 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,0534893 0,08479841 ! copper ion transport GO:0006825 22 15 0,000 0,0534893 0,08474342 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,0534893 0,0846885 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,0534893 0,08463365 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,0534893 0,08457887 ! sulfate transport GO:0008272 27 15 0,000 0,0534893 0,08452416 ! response to cAMP GO:0051591 25 15 0,000 0,0534893 0,08446952 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,0534893 0,08441495 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,0534893 0,08436046 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,0534893 0,08430603 ! response to hexose stimulus GO:0009746 25 15 0,000 0,0534893 0,08425168 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,0534893 0,08419739 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,0534893 0,08414317 ! vesicle coating GO:0006901 38 15 0,000 0,0534893 0,08408903 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,0534893 0,08403495 ! regulation of exocytosis GO:0017157 26 15 0,000 0,0534893 0,08398094 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,0534893 0,08392701 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,0534893 0,08387314 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,0534893 0,08381934 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,0534893 0,08376561 ! regulation of vasodilation GO:0042312 27 15 0,000 0,0534893 0,08371195 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,0534893 0,08365835 ! histone deacetylation GO:0016575 24 15 0,000 0,0534893 0,08360483 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0534893 0,08355137 ! water homeostasis GO:0030104 28 15 0,000 0,0534893 0,08349799 ! cofactor transport GO:0051181 30 15 0,000 0,0534893 0,08344467 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0534893 0,08339142 ! muscle maintenance GO:0046716 26 15 0,000 0,0534893 0,08333823 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,0534893 0,08328512 ! intestinal absorption GO:0050892 31 15 0,000 0,0534893 0,08323207 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0534893 0,08317909 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,0534893 0,08312618 ! heme biosynthetic process GO:0006783 33 15 0,000 0,0534893 0,08307333 ! cell killing GO:0001906 32 15 0,000 0,0534893 0,08302055 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,0534893 0,08296784 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,0534893 0,0829152 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,0534893 0,08286262 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,0534893 0,08281011 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,0534893 0,08275766 ! actin filament polymerization GO:0030041 27 15 0,000 0,0534893 0,08270528 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,0534893 0,08265297 ! positive regulation of cell size GO:0045793 29 16 0,000 0,05695256 0,08794887 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,05695256 0,08789331 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,05695256 0,08783782 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,05695256 0,0877824 ! bone remodeling GO:0046849 28 16 0,000 0,05695256 0,08772705 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,05695256 0,08767178 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,05695256 0,08761657 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05695256 0,08756143 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,05695256 0,08750636 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,05695256 0,08745136 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,05695256 0,08739642 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,05695256 0,08734156 ! startle response GO:0001964 28 16 0,000 0,05695256 0,08728677 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,05695256 0,08723204 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,05695256 0,08717739 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,05695256 0,0871228 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,05695256 0,08706828 ! protein polyubiquitination GO:0000209 41 16 0,000 0,05695256 0,08701383 ! pituitary gland development GO:0021983 30 16 0,000 0,05695256 0,08695944 ! response to osmotic stress GO:0006970 27 16 0,000 0,05695256 0,08690513 ! lysosomal transport GO:0007041 31 16 0,000 0,05695256 0,08685088 ! fructose metabolic process GO:0006000 25 16 0,000 0,05695256 0,0867967 ! L-amino acid transport GO:0015807 33 16 0,000 0,05695256 0,08674259 ! stem cell development GO:0048864 46 16 0,000 0,05695256 0,08668854 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05695256 0,08663456 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05695256 0,08658065 ! intermediate filament-based process GO:0045103 36 16 0,000 0,05695256 0,08652681 ! negative regulation of immune response GO:0050777 38 16 0,000 0,05695256 0,08647303 ! axon cargo transport GO:0008088 46 16 0,000 0,05695256 0,08641932 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,05695256 0,08636568 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,05695256 0,0863121 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,05695256 0,08625859 ! DNA replication initiation GO:0006270 28 16 0,000 0,05695256 0,08620515 ! neuron recognition GO:0008038 40 16 0,000 0,05695256 0,08615177 ! mRNA splice site selection GO:0006376 44 16 0,000 0,05695256 0,08609846 ! tissue regeneration GO:0042246 27 16 0,000 0,05695256 0,08604521 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,05695256 0,08599203 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,05695256 0,08593892 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,05695256 0,08588587 ! biomineral formation GO:0031214 22 16 0,000 0,05695256 0,08583289 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,05695256 0,08577997 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,05695256 0,08572712 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,05695256 0,08567433 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05695256 0,08562161 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,05695256 0,08556895 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,05695256 0,08551635 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,05695256 0,08546383 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,05695256 0,08541136 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,06040325 0,09053077 ! metencephalon development GO:0022037 32 17 0,000 0,06040325 0,09047526 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,06040325 0,09041982 ! signal complex assembly GO:0007172 47 17 0,000 0,06040325 0,09036445 ! endothelial cell migration GO:0043542 31 17 0,000 0,06040325 0,09030915 ! gene silencing by RNA GO:0031047 38 17 0,000 0,06040325 0,09025391 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,06040325 0,09019875 ! glial cell development GO:0021782 28 17 0,000 0,06040325 0,09014365 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,06040325 0,09008861 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,06040325 0,09003365 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,06040325 0,08997875 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,06040325 0,08992392 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,06040325 0,08986915 ! myoblast differentiation GO:0045445 50 17 0,000 0,06040325 0,08981445 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,06040325 0,08975982 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,06040325 0,08970526 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,06040325 0,08965076 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,06040325 0,08959633 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,06040325 0,08954196 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,06040325 0,08948766 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,06040325 0,08943342 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,06040325 0,08937925 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,06040325 0,08932515 ! membrane budding GO:0006900 42 17 0,000 0,06040325 0,08927111 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,06040325 0,08921714 ! regulation of protein binding GO:0043393 33 17 0,000 0,06040325 0,08916323 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,06040325 0,08910939 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,06040325 0,08905561 ! genitalia development GO:0048806 32 17 0,000 0,06040325 0,0890019 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,06040325 0,08894825 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,06040325 0,08889467 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,06040325 0,08884115 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,06040325 0,08878769 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,06040325 0,0887343 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,06040325 0,08868098 ! steroid catabolic process GO:0006706 34 17 0,000 0,06040325 0,08862772 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,06040325 0,08857452 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,06040325 0,08852138 ! gas transport GO:0015669 26 17 0,000 0,06040325 0,08846831 ! organic cation transport GO:0015695 32 17 0,000 0,06040325 0,08841531 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,06040325 0,08836236 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,06040325 0,08830948 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,06040325 0,08825667 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,06384142 0,09322449 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,06384142 0,0931688 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,06384142 0,09311318 ! limbic system development GO:0021761 40 18 0,000 0,06384142 0,09305762 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06384142 0,09300213 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,06384142 0,09294671 ! adult walking behavior GO:0007628 36 18 0,000 0,06384142 0,09289135 ! patterning of blood vessels GO:0001569 43 18 0,000 0,06384142 0,09283606 ! heart looping GO:0001947 34 18 0,000 0,06384142 0,09278083 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,06384142 0,09272567 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,06384142 0,09267057 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,06384142 0,09261554 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,06384142 0,09256058 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,06384142 0,09250568 ! glycine metabolic process GO:0006544 30 18 0,000 0,06384142 0,09245085 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06384142 0,09239608 ! response to retinoic acid GO:0032526 31 18 0,000 0,06384142 0,09234137 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,06384142 0,09228673 ! DNA integration GO:0015074 32 18 0,000 0,06384142 0,09223216 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,06384142 0,09217765 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,06384142 0,0921232 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,06384142 0,09206882 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,06384142 0,0920145 ! neural crest cell migration GO:0001755 41 18 0,000 0,06384142 0,09196025 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,06384142 0,09190606 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,06384142 0,09185193 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,06384142 0,09179787 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,06384142 0,09174387 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,06384142 0,09168993 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,06384142 0,09163606 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,06384142 0,09158225 ! detection of bacterium GO:0016045 22 18 0,000 0,06384142 0,09152851 ! nerve development GO:0021675 34 18 0,000 0,06384142 0,09147483 ! defense response to virus GO:0051607 43 18 0,000 0,06384142 0,09142121 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,06384142 0,09136765 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,06384142 0,09131416 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,06726709 0,0961577 ! positive regulation of translation GO:0045727 31 19 0,000 0,06726709 0,09610147 ! negative regulation of defense response GO:0031348 27 19 0,000 0,06726709 0,0960453 ! neuron maturation GO:0042551 46 19 0,000 0,06726709 0,0959892 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,06726709 0,09593316 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,06726709 0,09587719 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,06726709 0,09582129 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,06726709 0,09576545 ! memory GO:0007613 34 19 0,000 0,06726709 0,09570967 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,06726709 0,09565396 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,06726709 0,09559832 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,06726709 0,09554274 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,06726709 0,09548722 ! cerebral cortex development GO:0021987 40 19 0,000 0,06726709 0,09543177 ! pigmentation during development GO:0048066 42 19 0,000 0,06726709 0,09537638 ! response to vitamin A GO:0033189 32 19 0,000 0,06726709 0,09532106 ! heme metabolic process GO:0042168 40 19 0,000 0,06726709 0,0952658 ! neuromuscular junction development GO:0007528 43 19 0,000 0,06726709 0,09521061 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,06726709 0,09515548 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,06726709 0,09510041 ! response to fungus GO:0009620 26 19 0,000 0,06726709 0,09504541 ! peptide cross-linking GO:0018149 39 19 0,000 0,06726709 0,09499047 ! protein export from nucleus GO:0006611 40 19 0,000 0,06726709 0,09493559 ! heart process GO:0003015 32 19 0,000 0,06726709 0,09488078 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,06726709 0,09482603 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,06726709 0,09477134 ! visual learning GO:0008542 38 19 0,000 0,06726709 0,09471672 ! cellular pigmentation GO:0033059 37 19 0,000 0,06726709 0,09466216 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,06726709 0,09460766 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,06726709 0,09455323 ! vitamin transport GO:0051180 31 19 0,000 0,06726709 0,09449885 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,06726709 0,09444454 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,06726709 0,0943903 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,06726709 0,09433611 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,06726709 0,09428199 ! cilium assembly GO:0042384 38 19 0,000 0,06726709 0,09422793 ! peptide hormone secretion GO:0030072 32 19 0,000 0,06726709 0,09417393 ! protein secretion GO:0009306 45 20 0,000 0,07068033 0,09889579 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,07068033 0,09883918 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,07068033 0,09878264 ! positive regulation of ossification GO:0045778 50 20 0,000 0,07068033 0,09872616 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,07068033 0,09866974 ! skin development GO:0043588 42 20 0,000 0,07068033 0,09861339 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,07068033 0,0985571 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,07068033 0,09850088 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,07068033 0,09844472 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,07068033 0,09838863 ! response to vitamin GO:0033273 36 20 0,000 0,07068033 0,0983326 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,07068033 0,09827663 ! bile acid metabolic process GO:0008206 34 20 0,000 0,07068033 0,09822073 ! response to alkaloid GO:0043279 38 20 0,000 0,07068033 0,09816489 ! retinoid metabolic process GO:0001523 34 20 0,000 0,07068033 0,09810912 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,07068033 0,09805341 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,07068033 0,09799776 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,07068033 0,09794217 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,07068033 0,09788665 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,07068033 0,09783119 ! body fluid secretion GO:0007589 33 20 0,000 0,07068033 0,09777579 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,07068033 0,09772046 ! peptide secretion GO:0002790 38 20 0,000 0,07068033 0,09766519 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,07068033 0,09760998 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,07068033 0,09755483 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,07068033 0,09749974 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,07068033 0,09744472 ! cell-cell junction organization GO:0045216 43 20 0,000 0,07068033 0,09738976 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,07068033 0,09733486 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,07068033 0,09728003 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,07068033 0,09722525 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,07068033 0,09717054 ! regulation of glucose import GO:0046324 30 20 0,000 0,07068033 0,09711589 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,07068033 0,0970613 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,07068033 0,09700677 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,07068033 0,0969523 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,07068033 0,09689789 ! regulation of cell killing GO:0031341 46 21 0,000 0,07408117 0,10150326 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,07408117 0,10144636 ! hormone secretion GO:0046879 39 21 0,000 0,07408117 0,10138953 ! cAMP metabolic process GO:0046058 41 21 0,000 0,07408117 0,10133276 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,07408117 0,10127605 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,07408117 0,10121941 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,07408117 0,10116283 ! ovarian follicle development GO:0001541 39 21 0,000 0,07408117 0,10110632 ! smooth muscle contraction GO:0006939 48 21 0,000 0,07408117 0,10104986 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,07408117 0,10099348 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,07408117 0,10093715 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,07408117 0,10088088 ! plasma membrane fusion GO:0045026 33 21 0,000 0,07408117 0,10082468 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,07408117 0,10076855 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,07408117 0,10071247 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,07408117 0,10065646 ! sensory perception of pain GO:0019233 33 21 0,000 0,07408117 0,1006005 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,07408117 0,10054462 ! diencephalon development GO:0021536 36 21 0,000 0,07408117 0,10048879 ! collagen fibril organization GO:0030199 62 21 0,000 0,07408117 0,10043302 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,07408117 0,10037732 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,07408117 0,10032168 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,07408117 0,1002661 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,07408117 0,10021058 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,07408117 0,10015512 ! collagen catabolic process GO:0030574 29 21 0,000 0,07408117 0,10009973 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,07408117 0,10004439 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,07408117 0,09998912 ! sperm-egg recognition GO:0035036 23 21 0,000 0,07408117 0,09993391 ! actin filament-based movement GO:0030048 47 21 0,000 0,07408117 0,09987876 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,07746967 0,10438963 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,07746967 0,10433208 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,07746967 0,1042746 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,07746967 0,10421718 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,07746967 0,10415982 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,07746967 0,10410253 ! microtubule-based transport GO:0010970 59 22 0,000 0,07746967 0,1040453 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,07746967 0,10398813 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,07746967 0,10393103 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,07746967 0,10387398 ! vacuolar transport GO:0007034 41 22 0,000 0,07746967 0,103817 ! central nervous system neuron development GO:0021954 47 22 0,000 0,07746967 0,10376009 ! fucose metabolic process GO:0006004 44 22 0,000 0,07746967 0,10370323 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,07746967 0,10364644 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,07746967 0,10358971 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,07746967 0,10353304 ! stem cell differentiation GO:0048863 57 22 0,000 0,07746967 0,10347643 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,07746967 0,10341989 ! cytolysis GO:0019835 27 22 0,000 0,07746967 0,10336341 ! renal system process GO:0003014 42 22 0,000 0,07746967 0,10330699 ! vasodilation GO:0042311 40 22 0,000 0,07746967 0,10325063 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,07746967 0,10319433 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,07746967 0,10313809 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,07746967 0,10308192 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,07746967 0,1030258 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,07746967 0,10296975 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,07746967 0,10291376 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,07746967 0,10285782 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,07746967 0,10280195 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,07746967 0,10274614 ! sarcomere organization GO:0045214 32 22 0,000 0,07746967 0,10269039 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,07746967 0,10263471 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,07746967 0,10257908 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,07746967 0,10252351 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,07746967 0,102468 ! gut development GO:0048565 44 22 0,000 0,07746967 0,10241255 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,07746967 0,10235716 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,07746967 0,10230184 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,07746967 0,10224657 ! protein stabilization GO:0050821 41 22 0,000 0,07746967 0,10219136 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,08084585 0,10658738 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,08084585 0,10652989 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,08084585 0,10647247 ! gluconeogenesis GO:0006094 38 23 0,000 0,08084585 0,1064151 ! glycerol metabolic process GO:0006071 40 23 0,000 0,08084585 0,10635779 ! viral genome replication GO:0019079 44 23 0,000 0,08084585 0,10630055 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,08084585 0,10624337 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,08084585 0,10618625 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,08084585 0,10612919 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,08084585 0,10607219 ! regeneration GO:0031099 42 23 0,000 0,08084585 0,10601526 ! axis specification GO:0009798 43 23 0,000 0,08084585 0,10595838 ! visual behavior GO:0007632 46 23 0,000 0,08084585 0,10590157 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,08084585 0,10584481 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,08084585 0,10578812 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,08084585 0,10573149 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,08084585 0,10567492 ! peroxisome organization GO:0007031 43 23 0,000 0,08084585 0,10561841 ! lysosome organization GO:0007040 47 23 0,000 0,08084585 0,10556196 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,08084585 0,10550557 ! vesicle targeting GO:0006903 49 23 0,000 0,08084585 0,10544924 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,08084585 0,10539297 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,08084585 0,10533676 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,08084585 0,10528061 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,08084585 0,10522452 ! DNA modification GO:0006304 36 23 0,000 0,08084585 0,10516849 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,08084585 0,10511252 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,08084585 0,10505661 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,08084585 0,10500076 ! hormone transport GO:0009914 41 23 0,000 0,08084585 0,10494496 ! cell-cell recognition GO:0009988 28 23 0,000 0,08084585 0,10488923 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,08084585 0,10483356 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,08084585 0,10477794 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,08084585 0,10472239 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,08420978 0,10902199 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,08420978 0,10896425 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,08420978 0,10890656 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,08420978 0,10884894 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,08420978 0,10879138 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,08420978 0,10873388 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,08420978 0,10867644 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,08420978 0,10861906 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,08420978 0,10856174 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,08420978 0,10850448 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,08420978 0,10844728 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,08420978 0,10839015 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,08420978 0,10833307 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,08420978 0,10827605 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,08420978 0,10821909 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,08420978 0,1081622 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,08420978 0,10810536 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,08420978 0,10804858 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,08420978 0,10799186 ! membrane depolarization GO:0051899 45 24 0,000 0,08420978 0,1079352 ! pallium development GO:0021543 56 24 0,000 0,08420978 0,1078786 ! oogenesis GO:0048477 44 24 0,000 0,08420978 0,10782206 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,08420978 0,10776558 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,08420978 0,10770916 ! platelet activation GO:0030168 41 24 0,000 0,08420978 0,1076528 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,08420978 0,10759649 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,08420978 0,10754025 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,08420978 0,10748406 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,08420978 0,10742794 ! regulation of amine transport GO:0051952 41 24 0,000 0,08420978 0,10737187 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,08420978 0,10731586 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,08756149 0,11152905 ! leukocyte adhesion GO:0007159 55 25 0,000 0,08756149 0,11147093 ! phototransduction GO:0007602 37 25 0,000 0,08756149 0,11141288 ! keratinization GO:0031424 37 25 0,000 0,08756149 0,11135488 ! vacuole organization GO:0007033 49 25 0,000 0,08756149 0,11129694 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,08756149 0,11123907 ! receptor metabolic process GO:0043112 53 25 0,000 0,08756149 0,11118125 ! chromosome condensation GO:0030261 48 25 0,000 0,08756149 0,11112349 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,08756149 0,1110658 ! regulation of behavior GO:0050795 48 25 0,000 0,08756149 0,11100816 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,08756149 0,11095058 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,08756149 0,11089307 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,08756149 0,11083561 ! immunoglobulin production GO:0002377 62 25 0,000 0,08756149 0,11077821 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,08756149 0,11072087 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,08756149 0,11066359 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,08756149 0,11060637 ! liver development GO:0001889 55 25 0,000 0,08756149 0,11054921 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,09090103 0,1147062 ! myelination GO:0042552 50 26 0,000 0,09090103 0,11464699 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,09090103 0,11458783 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,09090103 0,11452873 ! molting cycle process GO:0022404 52 26 0,000 0,09090103 0,1144697 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,09090103 0,11441072 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,09090103 0,11435181 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,09090103 0,11429295 ! spinal cord development GO:0021510 54 26 0,000 0,09090103 0,11423416 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,09090103 0,11417543 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,09090103 0,11411676 ! digestive system process GO:0022600 49 26 0,000 0,09090103 0,11405815 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,09090103 0,1139996 ! osteoblast differentiation GO:0001649 63 26 0,000 0,09090103 0,1139411 ! neural crest cell development GO:0014032 59 26 0,000 0,09090103 0,11388267 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,09090103 0,1138243 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,09090103 0,11376599 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,09090103 0,11370774 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,09090103 0,11364955 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,09090103 0,11359141 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,09090103 0,11353334 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,09090103 0,11347533 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,09090103 0,11341737 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,09090103 0,11335947 ! blastocyst development GO:0001824 50 26 0,000 0,09090103 0,11330164 ! telomere organization GO:0032200 46 26 0,000 0,09090103 0,11324386 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,09090103 0,11318614 ! neural tube closure GO:0001843 58 26 0,000 0,09090103 0,11312848 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,09090103 0,11307088 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,09090103 0,11301334 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,09090103 0,11295586 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,09422844 0,11703105 ! embryonic pattern specification GO:0009880 49 27 0,000 0,09422844 0,11697158 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,09422844 0,11691217 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,09422844 0,11685283 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,09422844 0,11679354 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,09422844 0,11673431 ! iron ion transport GO:0006826 65 27 0,000 0,09422844 0,11667515 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,09422844 0,11661604 ! superoxide metabolic process GO:0006801 41 27 0,000 0,09422844 0,116557 ! tube lumen formation GO:0035148 59 27 0,000 0,09422844 0,11649801 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,09422844 0,11643908 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,09422844 0,11638022 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,09422844 0,11632141 ! response to toxin GO:0009636 49 27 0,000 0,09422844 0,11626266 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,09422844 0,11620397 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,09422844 0,11614534 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,09422844 0,11608677 ! leukocyte proliferation GO:0070661 59 27 0,000 0,09422844 0,11602826 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,09422844 0,11596981 ! neuron fate commitment GO:0048663 52 28 0,000 0,09754376 0,11998963 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,09754376 0,11992924 ! vesicle docking GO:0048278 55 28 0,000 0,09754376 0,11986891 ! circadian rhythm GO:0007623 56 28 0,000 0,09754376 0,11980865 ! dendrite development GO:0016358 67 28 0,000 0,09754376 0,11974844 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,09754376 0,1196883 ! fat cell differentiation GO:0045444 57 28 0,000 0,09754376 0,11962821 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,09754376 0,11956819 ! sperm motility GO:0030317 37 28 0,000 0,09754376 0,11950823 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,09754376 0,11944832 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,09754376 0,11938848 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,09754376 0,11932869 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,09754376 0,11926897 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,09754376 0,11920931 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,09754376 0,1191497 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,09754376 0,11909016 ! glutathione metabolic process GO:0006749 42 28 0,000 0,09754376 0,11903067 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,09754376 0,11897124 ! lipid oxidation GO:0034440 48 28 0,000 0,09754376 0,11891188 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,09754376 0,11885257 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,09754376 0,11879332 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,10084704 0,12275502 ! translational initiation GO:0006413 66 29 0,000 0,10084704 0,12269388 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,10084704 0,12263281 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,10084704 0,1225718 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,10084704 0,12251085 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,10084704 0,12244996 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,10084704 0,12238913 ! primary neural tube formation GO:0014020 61 29 0,000 0,10084704 0,12232836 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,10084704 0,12226765 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,10084704 0,122207 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,10084704 0,12214641 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,10084704 0,12208588 ! synaptogenesis GO:0007416 46 29 0,000 0,10084704 0,12202542 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,10084704 0,12196501 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,10084704 0,12190466 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,10084704 0,12184437 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,10084704 0,12178414 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,10413832 0,1256966 ! phenol metabolic process GO:0018958 56 30 0,000 0,10413832 0,12563453 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,10413832 0,12557252 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,10413832 0,12551057 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,10413832 0,12544868 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,10413832 0,12538685 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,10413832 0,12532508 ! acute-phase response GO:0006953 50 30 0,000 0,10413832 0,12526338 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,10413832 0,12520173 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,10413832 0,12514015 ! myofibril assembly GO:0030239 50 30 0,000 0,10413832 0,12507862 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,10413832 0,12501716 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,10413832 0,12495576 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,10413832 0,12489441 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,10413832 0,12483313 ! phospholipid transport GO:0015914 65 30 0,000 0,10413832 0,12477191 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,10413832 0,12471074 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,10413832 0,12464964 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,10413832 0,1245886 ! tissue homeostasis GO:0001894 50 30 0,000 0,10413832 0,12452762 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,10413832 0,12446669 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,10741765 0,12832338 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,10741765 0,12826066 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,10741765 0,128198 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,10741765 0,12813541 ! regulation of innate immune response GO:0045088 57 31 0,000 0,10741765 0,12807287 ! ovulation cycle process GO:0022602 55 31 0,000 0,10741765 0,1280104 ! peptide transport GO:0015833 60 31 0,000 0,10741765 0,12794798 ! iron ion homeostasis GO:0055072 60 31 0,000 0,10741765 0,12788563 ! detection of light stimulus GO:0009583 44 31 0,000 0,10741765 0,12782334 ! natural killer cell activation GO:0030101 50 31 0,000 0,10741765 0,12776111 ! ensheathment of neurons GO:0007272 64 31 0,000 0,10741765 0,12769894 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,10741765 0,12763683 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,10741765 0,12757478 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,10741765 0,12751279 ! eye morphogenesis GO:0048592 65 31 0,000 0,10741765 0,12745086 ! response to heat GO:0009408 54 31 0,000 0,10741765 0,12738899 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,10741765 0,12732718 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,11068506 0,13113657 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,11068506 0,131073 ! collagen metabolic process GO:0032963 49 32 0,000 0,11068506 0,1310095 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,11068506 0,13094606 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,11068506 0,13088268 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,11068506 0,13081936 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,11068506 0,1307561 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,11068506 0,1306929 ! muscle cell development GO:0055001 52 32 0,000 0,11068506 0,13062976 ! mesoderm formation GO:0001707 73 32 0,000 0,11068506 0,13056669 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,11068506 0,13050367 ! ovulation cycle GO:0042698 57 32 0,000 0,11068506 0,13044072 ! peripheral nervous system development GO:0007422 68 32 0,000 0,11068506 0,13037782 ! BMP signaling pathway GO:0030509 71 32 0,000 0,11068506 0,13031499 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,11068506 0,13025222 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,11068506 0,13018951 ! gene silencing GO:0016458 71 32 0,000 0,11068506 0,13012686 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,11394061 0,13388981 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,11394061 0,13382544 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,11394061 0,13376113 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,11394061 0,13369688 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,11394061 0,1336327 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,11394061 0,13356857 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,11394061 0,13350451 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,11394061 0,13344051 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,11394061 0,13337657 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,11394061 0,13331269 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,11394061 0,13324888 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,11718433 0,1369767 ! glial cell differentiation GO:0010001 67 34 0,000 0,11718433 0,1369112 ! post-embryonic development GO:0009791 76 34 0,000 0,11718433 0,13684575 ! cholesterol transport GO:0030301 62 34 0,000 0,11718433 0,13678037 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,11718433 0,13671505 ! spliceosome assembly GO:0000245 75 34 0,000 0,11718433 0,13664979 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,11718433 0,1365846 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,11718433 0,13651946 ! formation of primary germ layer GO:0001704 76 34 0,000 0,11718433 0,13645439 ! cell fate specification GO:0001708 56 34 0,000 0,11718433 0,13638938 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,11718433 0,13632443 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,11718433 0,13625955 ! adult locomotory behavior GO:0008344 62 34 0,000 0,11718433 0,13619473 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,12041626 0,13988442 ! negative regulation of secretion GO:0051048 68 35 0,000 0,12041626 0,13981793 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,12041626 0,13975151 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,12041626 0,13968515 ! membrane docking GO:0022406 69 35 0,000 0,12041626 0,13961886 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,12041626 0,13955262 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,12041626 0,13948645 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,12041626 0,13942035 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,12041626 0,1393543 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,12041626 0,13928832 ! ceramide metabolic process GO:0006672 72 35 0,000 0,12041626 0,1392224 ! telencephalon development GO:0021537 81 35 0,000 0,12041626 0,13915654 ! sterol transport GO:0015918 63 35 0,000 0,12041626 0,13909075 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,12041626 0,13902502 ! placenta development GO:0001890 53 35 0,000 0,12041626 0,13895934 ! vesicle localization GO:0051648 70 35 0,000 0,12041626 0,13889374 ! regulation of muscle development GO:0048634 82 36 0,000 0,12363646 0,14254076 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,12363646 0,14247352 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,12363646 0,14240635 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,12363646 0,14233924 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,12363646 0,14227219 ! positive regulation of cell development GO:0010720 85 36 0,000 0,12363646 0,14220521 ! protein targeting to membrane GO:0006612 75 36 0,000 0,12363646 0,14213829 ! regulation of proteolysis GO:0030162 77 36 0,000 0,12363646 0,14207143 ! aerobic respiration GO:0009060 56 36 0,000 0,12363646 0,14200464 ! cytokine production GO:0001816 68 36 0,000 0,12363646 0,14193791 ! embryonic organ development GO:0048568 67 36 0,000 0,12363646 0,14187124 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,12363646 0,14180463 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,12363646 0,14173809 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,12684495 0,14534813 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,12684495 0,14527999 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,12684495 0,14521191 ! sister chromatid segregation GO:0000819 65 37 0,000 0,12684495 0,1451439 ! odontogenesis GO:0042476 74 37 0,000 0,12684495 0,14507595 ! actomyosin structure organization GO:0031032 68 37 0,000 0,12684495 0,14500806 ! tissue remodeling GO:0048771 78 37 0,000 0,12684495 0,14494023 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,12684495 0,14487247 ! female gonad development GO:0008585 71 37 0,000 0,12684495 0,14480478 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,12684495 0,14473714 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,12684495 0,14466957 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,13004179 0,14824643 ! meiosis I GO:0007127 74 38 0,000 0,13004179 0,14817728 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,13004179 0,1481082 ! organic anion transport GO:0015711 82 38 0,000 0,13004179 0,14803919 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,13004179 0,14797024 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,13004179 0,14790135 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,13004179 0,14783253 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,13004179 0,14776377 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,13004179 0,14769507 ! regulation of protein stability GO:0031647 77 38 0,000 0,13004179 0,14762644 ! spermatid development GO:0007286 69 38 0,000 0,13004179 0,14755787 ! glycogen metabolic process GO:0005977 63 38 0,000 0,13004179 0,14748937 ! pigment metabolic process GO:0042440 87 38 0,000 0,13004179 0,14742093 ! neural tube formation GO:0001841 79 38 0,000 0,13004179 0,14735255 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,13322702 0,15089179 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,13322702 0,15082187 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,13322702 0,15075202 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,13322702 0,15068222 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,13322702 0,15061249 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,13322702 0,15054283 ! glucan metabolic process GO:0044042 64 39 0,000 0,13322702 0,15047323 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,13640067 0,15398652 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,13640067 0,1539154 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,13640067 0,15384434 ! learning GO:0007612 82 40 0,000 0,13640067 0,15377334 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,13640067 0,15370241 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,13640067 0,15363155 ! lipid homeostasis GO:0055088 75 40 0,000 0,13640067 0,15356075 ! mismatch repair GO:0006298 58 40 0,000 0,13640067 0,15349002 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,13640067 0,15341935 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,13640067 0,15334875 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,13640067 0,15327821 ! RNA export from nucleus GO:0006405 61 41 0,000 0,13956279 0,15675949 ! mRNA catabolic process GO:0006402 79 41 0,000 0,13956279 0,15668745 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,13956279 0,15661548 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,13956279 0,15654357 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,13956279 0,15647173 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,13956279 0,15639995 ! feeding behavior GO:0007631 69 41 0,000 0,13956279 0,15632824 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,13956279 0,1562566 ! mesenchymal cell development GO:0014031 94 41 0,000 0,13956279 0,15618502 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,13956279 0,1561135 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,13956279 0,15604206 ! spermatid differentiation GO:0048515 73 41 0,000 0,13956279 0,15597067 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,13956279 0,15589936 ! RNA modification GO:0009451 64 41 0,000 0,13956279 0,1558281 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,14271342 0,15927313 ! organic ether metabolic process GO:0018904 59 42 0,000 0,14271342 0,1592004 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,14271342 0,15912774 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,14271342 0,15905515 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,14271342 0,15898262 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,14271342 0,15891016 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,14271342 0,15883776 ! regulation of protein secretion GO:0050708 77 42 0,000 0,14271342 0,15876543 ! cytokinesis GO:0000910 84 42 0,000 0,14271342 0,15869316 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,14271342 0,15862097 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,1458526 0,16203634 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,1458526 0,16196268 ! regulation of tube size GO:0035150 76 43 0,000 0,1458526 0,1618891 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,1458526 0,16181558 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,1458526 0,16174213 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,1458526 0,16166874 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,1458526 0,16159542 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,1458526 0,16152217 ! ion transmembrane transport GO:0034220 79 43 0,000 0,1458526 0,16144898 ! neuron migration GO:0001764 85 43 0,000 0,1458526 0,16137586 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,14898038 0,16476191 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,14898038 0,16468736 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,14898038 0,16461287 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,14898038 0,16453845 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,14898038 0,1644641 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,14898038 0,16438982 ! striated muscle contraction GO:0006941 85 44 0,000 0,14898038 0,1643156 ! phagocytosis GO:0006909 105 44 0,000 0,14898038 0,16424145 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,14898038 0,16416737 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,15209679 0,1675259 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,15209679 0,16745041 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,15209679 0,16737498 ! biopolymer methylation GO:0043414 91 45 0,000 0,15209679 0,16729962 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,15209679 0,16722432 ! female gamete generation GO:0007292 71 45 0,000 0,15209679 0,1671491 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,15209679 0,16707394 ! developmental growth GO:0048589 88 45 0,000 0,15209679 0,16699885 ! maintenance of location in cell GO:0051651 101 45 0,000 0,15209679 0,16692383 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,15520187 0,17025513 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,15520187 0,17017871 ! glycolysis GO:0006096 71 46 0,000 0,15520187 0,17010237 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,15520187 0,17002609 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,15520187 0,16994988 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,15520187 0,16987373 ! cell growth GO:0016049 90 46 0,000 0,15520187 0,16979766 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,15520187 0,16972165 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,15829567 0,17302744 ! positive regulation of defense response GO:0031349 88 48 0,000 0,16137823 0,17631799 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,16137823 0,17623917 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,16137823 0,17616042 ! cellular component disassembly GO:0022411 89 48 0,000 0,16137823 0,17608174 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,16137823 0,17600313 ! endosome transport GO:0016197 127 48 0,000 0,16137823 0,1759246 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,16137823 0,17584613 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,16137823 0,17576773 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,16137823 0,1756894 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,16137823 0,17561114 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,16137823 0,17553296 ! methylation GO:0032259 97 48 0,000 0,16137823 0,17545484 ! response to calcium ion GO:0051592 94 49 0,000 0,16444959 0,17871456 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,16444959 0,1786351 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,16444959 0,17855571 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,16444959 0,17847638 ! JNK cascade GO:0007254 106 49 0,000 0,16444959 0,17839713 ! protein homooligomerization GO:0051260 84 49 0,000 0,16444959 0,17831795 ! regulation of action potential GO:0001508 102 50 0,000 0,16750978 0,18155563 ! regulation of ion transport GO:0043269 86 50 0,000 0,16750978 0,18147512 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,16750978 0,18139468 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,16750978 0,18131431 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,16750978 0,18123401 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,16750978 0,18115378 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,16750978 0,18107362 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,16750978 0,18099354 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,17055885 0,18420657 ! peptide metabolic process GO:0006518 80 51 0,000 0,17055885 0,18412518 ! response to temperature stimulus GO:0009266 84 51 0,000 0,17055885 0,18404385 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,17055885 0,18396259 ! Notch signaling pathway GO:0007219 111 52 0,000 0,17359684 0,1871567 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,17359684 0,18707414 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,17359684 0,18699166 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,17359684 0,18690925 ! excretion GO:0007588 87 52 0,000 0,17359684 0,18682691 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,17359684 0,18674464 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,17359684 0,18666245 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,17359684 0,18658033 ! amino acid activation GO:0043038 98 52 0,000 0,17359684 0,18649828 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,17662379 0,18966677 ! chromatin remodeling GO:0006338 122 53 0,000 0,17662379 0,18958344 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,17662379 0,18950018 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,17662379 0,18941699 ! vesicle organization GO:0016050 127 53 0,000 0,17662379 0,18933388 ! cartilage development GO:0051216 99 53 0,000 0,17662379 0,18925084 ! synapse organization GO:0050808 102 53 0,000 0,17662379 0,18916787 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,17963973 0,1923137 ! regulation of translational initiation GO:0006446 87 54 0,000 0,17963973 0,19222946 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,17963973 0,1921453 ! neuromuscular process GO:0050905 107 54 0,000 0,17963973 0,19206121 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,17963973 0,19197719 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,17963973 0,19189325 ! membrane fusion GO:0006944 122 54 0,000 0,17963973 0,19180938 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,17963973 0,19172559 ! regulation of cell shape GO:0008360 142 54 0,000 0,17963973 0,19164186 ! RNA catabolic process GO:0006401 103 55 0,000 0,18264471 0,19476257 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,18264471 0,19467759 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,18264471 0,19459269 ! cell recognition GO:0008037 98 55 0,000 0,18264471 0,19450786 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,18264471 0,19442311 ! cell maturation GO:0048469 107 55 0,000 0,18264471 0,19433843 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,18264471 0,19425383 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,18563877 0,19735227 ! glucose catabolic process GO:0006007 88 56 0,000 0,18563877 0,19726643 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,18563877 0,19718066 ! RNA elongation GO:0006354 90 56 0,000 0,18563877 0,19709497 ! chloride transport GO:0006821 102 57 0,000 0,18862195 0,20017525 ! muscle fiber development GO:0048747 131 57 0,000 0,18862195 0,20008833 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,18862195 0,20000149 ! regulation of actin filament length GO:0030832 118 58 0,000 0,19159428 0,203065 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,19159428 0,20297694 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,19159428 0,20288896 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,19159428 0,20280105 ! gastrulation GO:0007369 122 58 0,000 0,19159428 0,20271322 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,19159428 0,20262547 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,19159428 0,20253779 ! maintenance of location GO:0051235 124 58 0,000 0,19159428 0,20245019 ! nuclear export GO:0051168 110 59 0,000 0,19455581 0,20549064 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,19750657 0,20851709 ! DNA catabolic process GO:0006308 94 60 0,000 0,19750657 0,20842702 ! regulation of endocytosis GO:0030100 104 60 0,000 0,19750657 0,20833703 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,19750657 0,20824711 ! adult behavior GO:0030534 104 60 0,000 0,19750657 0,20815727 ! positive regulation of secretion GO:0051047 110 61 0,000 0,2004466 0,21116475 ! regulation of cellular component size GO:0032535 125 61 0,000 0,2004466 0,21107373 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,2004466 0,21098279 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,2004466 0,21089193 ! regulation of heart contraction GO:0008016 123 61 0,000 0,2004466 0,21080114 ! proton transport GO:0015992 117 61 0,000 0,2004466 0,21071044 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,2004466 0,21061981 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,20337595 0,21360595 ! tRNA processing GO:0008033 102 62 0,000 0,20337595 0,21351416 ! mesoderm development GO:0007498 128 63 0,000 0,20629464 0,21648532 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,20629464 0,21639236 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,20629464 0,21629949 ! hydrogen transport GO:0006818 121 64 0,000 0,20920273 0,21925451 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,20920273 0,21916049 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,21210024 0,22210068 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,21210024 0,22200552 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,21210024 0,22191044 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,21210024 0,22181544 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,21210024 0,22172053 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,21498721 0,22464232 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,21786369 0,22755066 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,21786369 0,22745341 ! secondary metabolic process GO:0019748 125 67 0,000 0,21786369 0,22735625 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,22072971 0,23024879 ! hexose catabolic process GO:0019320 113 68 0,000 0,22072971 0,23015052 ! extracellular matrix organization GO:0030198 146 68 0,000 0,22072971 0,23005233 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,22072971 0,22995423 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,22072971 0,22985621 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,22072971 0,22975828 ! adaptive immune response GO:0002250 126 68 0,000 0,22072971 0,22966042 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,2235853 0,23253252 ! developmental maturation GO:0021700 128 69 0,000 0,2235853 0,23243357 ! single fertilization GO:0007338 83 69 0,000 0,2235853 0,23233471 ! cell redox homeostasis GO:0045454 114 70 0,000 0,22643051 0,23519122 ! activation of immune response GO:0002253 120 70 0,000 0,22643051 0,23509127 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,22643051 0,2349914 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,22926538 0,23783241 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,22926538 0,23773146 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,23208994 0,24055822 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,23208994 0,2404562 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,23208994 0,24035427 ! humoral immune response GO:0006959 115 73 0,000 0,23490422 0,24316568 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,23490422 0,24306269 ! regulation of immune effector process GO:0002697 156 73 0,000 0,23490422 0,24295979 ! acute inflammatory response GO:0002526 118 74 0,000 0,23770827 0,24575595 ! amino acid transport GO:0006865 148 74 0,000 0,23770827 0,24565199 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,23770827 0,24554812 ! transition metal ion transport GO:0000041 143 75 0,000 0,24050212 0,24832912 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,24050212 0,2482242 ! axon guidance GO:0007411 162 75 0,000 0,24050212 0,24811938 ! rhythmic process GO:0048511 142 75 0,000 0,24050212 0,24801464 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,24328581 0,25077943 ! learning or memory GO:0007611 161 76 0,000 0,24328581 0,25067366 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,24328581 0,25056798 ! regulation of blood pressure GO:0008217 134 76 0,000 0,24328581 0,25046239 ! neurotransmitter transport GO:0006836 142 77 0,000 0,24605938 0,25321106 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,24605938 0,25310445 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,24605938 0,25299792 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,24605938 0,25289149 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,24882286 0,25562416 ! antigen processing and presentation GO:0019882 117 78 0,000 0,24882286 0,25551671 ! fertilization GO:0009566 99 78 0,000 0,24882286 0,25540935 ! blood coagulation GO:0007596 151 79 0,000 0,25157629 0,2581272 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,25157629 0,25801884 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,25157629 0,25791056 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,25157629 0,25780238 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,2543197 0,26050441 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,2543197 0,26039523 ! muscle cell differentiation GO:0042692 178 81 0,000 0,25705313 0,2630837 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,25705313 0,26297353 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,2624902 0,26842342 ! exocytosis GO:0006887 153 83 0,000 0,2624902 0,26831111 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,2624902 0,2681989 ! inorganic anion transport GO:0015698 156 83 0,000 0,2624902 0,26808677 ! response to metal ion GO:0010038 158 84 0,000 0,26519391 0,27073494 ! response to nutrient GO:0007584 135 84 0,000 0,26519391 0,27062186 ! digestion GO:0007586 130 84 0,000 0,26519391 0,27050886 ! hemostasis GO:0007599 165 85 0,000 0,26788778 0,27314268 ! negative regulation of transport GO:0051051 164 85 0,000 0,26788778 0,27302873 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,26788778 0,27291487 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,26788778 0,27280111 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,26788778 0,27268744 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,26788778 0,27257387 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,27057186 0,27519028 ! regulation of lyase activity GO:0051339 169 86 0,000 0,27057186 0,27507576 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,27324617 0,27767903 ! alcohol catabolic process GO:0046164 142 87 0,000 0,27324617 0,27756357 ! nucleosome assembly GO:0006334 126 87 0,000 0,27324617 0,27744821 ! regulation of protein transport GO:0051223 165 87 0,000 0,27324617 0,27733294 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,27591075 0,27992108 ! sensory perception of smell GO:0007608 117 88 0,000 0,27591075 0,27980488 ! chromatin assembly GO:0031497 128 88 0,000 0,27591075 0,27968878 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,27591075 0,27957277 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,27856563 0,28214587 ! cellular defense response GO:0006968 123 89 0,000 0,27856563 0,28202894 ! regulation of neurological system process GO:0031644 175 89 0,000 0,27856563 0,28191211 ! response to inorganic substance GO:0010035 173 90 0,000 0,28121086 0,28447127 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,28121086 0,28435353 ! response to unfolded protein GO:0006986 139 90 0,000 0,28121086 0,28423588 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,28384646 0,28678118 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,28384646 0,28666263 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,28647247 0,28919514 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,28908893 0,29171592 ! amine transport GO:0015837 181 93 0,000 0,28908893 0,29159548 ! vitamin metabolic process GO:0006766 153 93 0,000 0,28908893 0,29147513 ! female pregnancy GO:0007565 166 94 0,000 0,29169586 0,29398225 ! sterol metabolic process GO:0016125 166 94 0,000 0,29169586 0,29386103 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,29169586 0,2937399 ! regulation of membrane potential GO:0042391 179 94 0,000 0,29169586 0,29361887 ! regulation of defense response GO:0031347 171 95 0,000 0,29429331 0,29611143 ! nucleosome organization GO:0034728 143 95 0,000 0,29429331 0,29598952 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,29429331 0,29586772 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,29429331 0,29574601 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,29429331 0,2956244 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,29429331 0,2955029 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,29429331 0,29538149 ! response to protein stimulus GO:0051789 158 96 0,000 0,2968813 0,29785668 ! regulation of T cell activation GO:0050863 175 96 0,000 0,2968813 0,29773441 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,29945988 0,30019717 ! transcription initiation GO:0006352 171 97 0,000 0,29945988 0,30007403 ! regulation of protein localization GO:0032880 188 97 0,000 0,29945988 0,299951 ! forebrain development GO:0030900 210 98 0,000 0,30202908 0,30240042 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,30202908 0,30227654 ! positive regulation of immune response GO:0050778 175 100 0,000 0,30713945 0,30726522 ! hormone metabolic process GO:0042445 171 100 0,000 0,30713945 0,30713945