pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1103-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 10 5 2,000 1,182E-06 2,719E-03 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 1,182E-06 1,359E-03 GO:0031272|regulation of pseudopodium assembly, ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 1,559E-06 1,195E-03 ! macrophage differentiation GO:0030225 10 6 2,000 2,355E-06 1,354E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 3,000 3,21E-06 1,477E-03 ! regulation of fibroblast proliferation GO:0048145 35 22 3,000 3,908E-06 1,498E-03 ! regulation of lipid kinase activity GO:0043550 12 7 2,000 4,107E-06 1,349E-03 ! establishment of nucleus localization GO:0040023 13 7 2,000 4,107E-06 1,181E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 5,000 4,361E-06 1,114E-03 ! interphase GO:0051325 159 88 5,000 4,987E-06 1,147E-03 ! insulin receptor signaling pathway GO:0008286 40 24 3,000 5,634E-06 1,178E-03 ! nucleus localization GO:0051647 15 9 2,000 9,786E-06 1,876E-03 ! myeloid cell differentiation GO:0030099 85 59 4,000 1,101E-05 1,948E-03 ! regulation of cell projection assembly GO:0060491 20 10 2,000 1,393E-05 2,288E-03 ! metanephros development GO:0001656 58 31 3,000 1,625E-05 2,491E-03 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 2,000 1,908E-05 2,743E-03 ! filopodium assembly GO:0046847 19 11 2,000 1,908E-05 2,582E-03 ! androgen receptor signaling pathway GO:0030521 54 33 3,000 2,097E-05 2,679E-03 ! cellular response to insulin stimulus GO:0032869 52 34 3,000 2,367E-05 2,866E-03 ! microspike assembly GO:0030035 23 12 2,000 2,535E-05 2,916E-03 ! regulation of monooxygenase activity GO:0032768 26 13 2,000 3,284E-05 3,597E-03 ! G1 phase of mitotic cell cycle GO:0000080 23 14 2,000 4,165E-05 4,354E-03 ! response to insulin stimulus GO:0032868 63 43 3,000 6,089E-05 6,089E-03 ! G1 phase GO:0051318 27 16 2,000 6,362E-05 6,096E-03 ! regulation of DNA metabolic process GO:0051052 135 85 4,000 6,52E-05 5,998E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 7,295E-05 6,454E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 7,697E-05 6,557E-03 ! actin filament bundle formation GO:0051017 26 17 2,000 7,697E-05 6,323E-03 ! response to UV GO:0009411 75 46 3,000 7,96E-05 6,313E-03 ! regulation of DNA replication GO:0006275 75 48 3,000 9,42E-05 7,222E-03 ! positive regulation of fibroblast proliferation GO:0048146 27 19 2,000 1,089E-04 8,079E-03 ! sex determination GO:0007530 29 19 2,000 1,089E-04 7,827E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 1,277E-04 8,897E-03 ! kidney development GO:0001822 90 53 3,000 1,391E-04 9,41E-03 ! myeloid leukocyte differentiation GO:0002573 33 21 2,000 1,484E-04 9,751E-03 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 1,484E-04 9,481E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 2,000 1,712E-04 0,01064247 ! protein tetramerization GO:0051262 39 22 2,000 1,712E-04 0,0103624 ! DNA damage response, signal transduction GO:0042770 96 56 3,000 1,725E-04 0,01017336 ! regulation of lipid metabolic process GO:0019216 84 56 3,000 1,725E-04 9,919E-03 ! response to peptide hormone stimulus GO:0043434 84 57 3,000 1,848E-04 0,01036815 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 1,962E-04 0,01074312 ! steroid hormone receptor signaling pathway GO:0030518 96 58 3,000 1,978E-04 0,0105781 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 2,234E-04 0,01167769 ! regulation of oxidoreductase activity GO:0051341 39 24 2,000 2,234E-04 0,01141819 ! urogenital system development GO:0001655 101 61 3,000 2,405E-04 0,01202537 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 2,425E-04 0,01186482 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 2,425E-04 0,01161764 ! positive regulation of glycolysis GO:0045821 11 5 1,000 2,425E-04 0,01138055 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 2,425E-04 0,01115293 ! induction of apoptosis by oxidative stress GO:0008631 5 5 1,000 2,425E-04 0,01093425 ! regulation of centrosome cycle GO:0046605 7 5 1,000 2,425E-04 0,01072398 ! neural tube patterning GO:0021532 6 5 1,000 2,425E-04 0,01052164 ! regulation of respiratory burst GO:0060263 8 5 1,000 2,425E-04 0,01032679 ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 2,425E-04 0,01013903 ! negative regulation of cell growth GO:0030308 106 62 3,000 2,561E-04 0,01051937 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 3,000 2,725E-04 0,01099385 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 2,849E-04 0,01129852 ! cell cycle checkpoint GO:0000075 108 64 3,000 2,895E-04 0,01128651 ! negative regulation of cell size GO:0045792 108 64 3,000 2,895E-04 0,0110984 ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 3,564E-04 0,01343905 ! positive regulation of protein ubiquitination GO:0031398 8 6 1,000 3,625E-04 0,01344776 ! positive regulation of DNA repair GO:0045739 7 6 1,000 3,625E-04 0,01323431 ! regulation of helicase activity GO:0051095 11 6 1,000 3,625E-04 0,01302752 ! male meiosis GO:0007140 7 6 1,000 3,625E-04 0,0128271 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 3,625E-04 0,01263275 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 3,625E-04 0,0124442 ! glutamate catabolic process GO:0006538 10 6 1,000 3,625E-04 0,0122612 ! ER overload response GO:0006983 7 6 1,000 3,625E-04 0,0120835 ! male sex determination GO:0030238 9 6 1,000 3,625E-04 0,01191088 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 1,000 3,625E-04 0,01174312 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 3,625E-04 0,01158002 ! negative regulation of oxidoreductase activity GO:0051354 10 6 1,000 3,625E-04 0,01142139 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 3,625E-04 0,01126705 ! midbrain development GO:0030901 6 6 1,000 3,625E-04 0,01111682 ! aspartate family amino acid catabolic process GO:0009068 7 6 1,000 3,625E-04 0,01097054 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 1,000 3,625E-04 0,01082807 ! eye development GO:0001654 111 70 3,000 4,084E-04 0,01204369 ! DNA damage checkpoint GO:0000077 53 31 2,000 4,838E-04 0,01408565 ! cellular response to hormone stimulus GO:0032870 109 74 3,000 5,049E-04 0,01451506 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 5,059E-04 0,01436404 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 1,000 5,059E-04 0,01418887 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 5,059E-04 0,01401792 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 5,059E-04 0,01385104 ! protein heterooligomerization GO:0051291 10 7 1,000 5,059E-04 0,01368809 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 5,059E-04 0,01352892 ! B cell lineage commitment GO:0002326 17 7 1,000 5,059E-04 0,01337342 ! T cell lineage commitment GO:0002360 12 7 1,000 5,059E-04 0,01322145 ! response to tumor cell GO:0002347 12 7 1,000 5,059E-04 0,01307289 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 1,000 5,059E-04 0,01292764 ! negative regulation of growth GO:0045926 123 75 3,000 5,313E-04 0,01342861 ! positive regulation of DNA metabolic process GO:0051054 54 33 2,000 5,83E-04 0,01457613 ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 6,372E-04 0,01575816 ! mitotic cell cycle checkpoint GO:0007093 63 34 2,000 6,372E-04 0,01559052 ! DNA integrity checkpoint GO:0031570 57 34 2,000 6,372E-04 0,01542641 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 6,723E-04 0,01610726 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 1,000 6,723E-04 0,0159412 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 6,723E-04 0,01577854 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 6,723E-04 0,01561916 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 6,723E-04 0,01546297 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 6,723E-04 0,01530987 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 1,000 6,723E-04 0,01515977 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 6,723E-04 0,01501259 ! regulation of embryonic development GO:0045995 16 8 1,000 6,723E-04 0,01486824 ! regulation of developmental growth GO:0048638 13 9 1,000 8,616E-04 0,018873 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 8,616E-04 0,01869495 ! regulation of glycolysis GO:0006110 15 9 1,000 8,616E-04 0,01852023 ! epithelial cell development GO:0002064 10 9 1,000 8,616E-04 0,01834875 ! postreplication repair GO:0006301 11 9 1,000 8,616E-04 0,01818041 ! localization within membrane GO:0051668 15 9 1,000 8,616E-04 0,01801513 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 9,558E-04 0,0198054 ! double-strand break repair GO:0006302 67 40 2,000 1,03E-03 0,02114413 ! regulation of myeloid cell differentiation GO:0045637 69 40 2,000 1,03E-03 0,02095702 ! leukocyte differentiation GO:0002521 143 90 3,000 1,056E-03 0,0212954 ! thyroid gland development GO:0030878 19 10 1,000 1,074E-03 0,02147018 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,074E-03 0,0212851 ! negative regulation of lipid metabolic process GO:0045833 14 10 1,000 1,074E-03 0,02110317 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,074E-03 0,02092433 ! response to X-ray GO:0010165 16 10 1,000 1,074E-03 0,0207485 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 1,074E-03 0,02057559 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 1,074E-03 0,02040555 GO:0043470|regulation of carbohydrate catabolic process, ! epithelial cell differentiation GO:0030855 55 41 2,000 1,107E-03 0,02086853 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 1,272E-03 0,02379181 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 1,272E-03 0,02359994 ! virus-host interaction GO:0019048 17 11 1,000 1,308E-03 0,02406399 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 1,308E-03 0,02387301 GO:0000725|recombinational repair, ! focal adhesion formation GO:0048041 24 11 1,000 1,308E-03 0,02368503 ! regulation of intracellular pH GO:0051453 17 11 1,000 1,308E-03 0,02349999 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 1,308E-03 0,02331782 ! response to light stimulus GO:0009416 153 96 3,000 1,342E-03 0,02373584 ! regulation of cell projection organization GO:0031344 83 44 2,000 1,361E-03 0,02388771 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 1,564E-03 0,02725709 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 1,564E-03 0,02705215 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 1,564E-03 0,02685027 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,564E-03 0,02665138 ! response to gamma radiation GO:0010332 20 12 1,000 1,564E-03 0,02645541 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,843E-03 0,03093702 ! glutamate metabolic process GO:0006536 18 13 1,000 1,843E-03 0,03071284 ! regulation of DNA repair GO:0006282 15 13 1,000 1,843E-03 0,03049189 ! regulation of cellular pH GO:0030641 20 13 1,000 1,843E-03 0,03027409 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 2,086E-03 0,03403397 ! positive regulation of cell migration GO:0030335 92 51 2,000 2,086E-03 0,03379429 ! regulation of lipid biosynthetic process GO:0046890 16 14 1,000 2,143E-03 0,03446715 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 2,143E-03 0,03422779 ! inositol metabolic process GO:0006020 20 14 1,000 2,143E-03 0,03399174 ! cellular response to starvation GO:0009267 21 14 1,000 2,143E-03 0,03375892 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 2,143E-03 0,03352926 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 2,143E-03 0,03330272 ! G1/S transition checkpoint GO:0031575 33 14 1,000 2,143E-03 0,03307921 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 2,143E-03 0,03285868 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,143E-03 0,03264107 ! establishment of organelle localization GO:0051656 85 52 2,000 2,206E-03 0,03338431 ! cell projection assembly GO:0030031 76 53 2,000 2,33E-03 0,03503061 ! regulation of protein complex assembly GO:0043254 81 54 2,000 2,459E-03 0,0367189 ! regulation of protein ubiquitination GO:0031396 19 15 1,000 2,465E-03 0,03657241 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 2,465E-03 0,03633797 ! embryonic forelimb morphogenesis GO:0035115 17 15 1,000 2,465E-03 0,03610652 ! lipid phosphorylation GO:0046834 23 15 1,000 2,465E-03 0,035878 ! centrosome cycle GO:0007098 16 15 1,000 2,465E-03 0,03565235 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 1,000 2,465E-03 0,03542952 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 2,465E-03 0,03520946 ! positive regulation of cell motion GO:0051272 99 56 2,000 2,728E-03 0,0387314 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 2,808E-03 0,03961742 ! protein amino acid acetylation GO:0006473 28 16 1,000 2,808E-03 0,03937585 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 1,000 2,808E-03 0,03913721 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 2,808E-03 0,03890144 ! negative regulation of translation GO:0017148 22 16 1,000 2,808E-03 0,0386685 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 2,869E-03 0,03928246 ! camera-type eye development GO:0043010 88 57 2,000 2,869E-03 0,03905002 ! negative regulation of kinase activity GO:0033673 100 58 2,000 3,015E-03 0,04079184 ! actin filament organization GO:0007015 95 59 2,000 3,165E-03 0,0425735 ! forelimb morphogenesis GO:0035136 19 17 1,000 3,172E-03 0,0424131 ! cell-substrate junction assembly GO:0007044 39 17 1,000 3,172E-03 0,04216794 ! proximal/distal pattern formation GO:0009954 25 17 1,000 3,172E-03 0,04192559 ! negative regulation of transferase activity GO:0051348 105 61 2,000 3,479E-03 0,04572727 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 3,479E-03 0,04546745 ! positive regulation of DNA replication GO:0045740 29 18 1,000 3,557E-03 0,04621738 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 3,557E-03 0,04595773 ! somitogenesis GO:0001756 24 18 1,000 3,557E-03 0,04570098 ! cellular response to nutrient levels GO:0031669 27 18 1,000 3,557E-03 0,04544709 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 3,557E-03 0,045196 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 3,643E-03 0,04603963 ! organelle localization GO:0051640 96 62 2,000 3,643E-03 0,04578805 ! regulation of transcription factor activity GO:0051090 97 63 2,000 3,812E-03 0,04764588 GO:0090046|regulation of transcription regulator activity, ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 3,962E-03 0,04926173 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 3,962E-03 0,04899688 GO:0010675|regulation of cellular carbohydrate metabolic process, ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 3,962E-03 0,04873486 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 3,962E-03 0,04847563 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 3,962E-03 0,04821915 ! response to starvation GO:0042594 30 19 1,000 3,962E-03 0,04796536 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 3,962E-03 0,04771424 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 3,962E-03 0,04746572 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 4,163E-03 0,04960893 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 4,163E-03 0,04935321 ! protein oligomerization GO:0051259 100 65 2,000 4,163E-03 0,04910012 ! response to ethanol GO:0045471 37 20 1,000 4,388E-03 0,05149694 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 4,388E-03 0,05123553 ! positive regulation of B cell activation GO:0050871 31 20 1,000 4,388E-03 0,05097676 ! protein amino acid acylation GO:0043543 37 21 1,000 4,835E-03 0,05587908 ! cell aging GO:0007569 32 21 1,000 4,835E-03 0,05559968 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 4,835E-03 0,05532306 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 4,835E-03 0,05504919 ! fatty acid transport GO:0015908 30 21 1,000 4,835E-03 0,05477801 ! glutamine family amino acid catabolic process GO:0009065 30 21 1,000 4,835E-03 0,05450949 ! response to drug GO:0042493 108 69 2,000 4,923E-03 0,05522944 ! positive regulation of ligase activity GO:0051351 99 69 2,000 4,923E-03 0,05496133 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 5,301E-03 0,05890122 ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 5,301E-03 0,05861804 ! vasculogenesis GO:0001570 33 22 1,000 5,301E-03 0,05833757 ! microtubule organizing center organization GO:0031023 28 22 1,000 5,301E-03 0,05805977 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 5,301E-03 0,05778461 GO:0010810|regulation of cell-substrate adhesion, ! ureteric bud development GO:0001657 32 22 1,000 5,301E-03 0,05751204 ! aspartate family amino acid metabolic process GO:0009066 24 22 1,000 5,301E-03 0,05724203 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 5,332E-03 0,05730461 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 5,787E-03 0,06191058 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 5,787E-03 0,06162396 ! negative regulation of DNA replication GO:0008156 35 23 1,000 5,787E-03 0,06133998 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 5,787E-03 0,0610586 ! interaction with host GO:0051701 37 23 1,000 5,787E-03 0,0607798 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 5,787E-03 0,06050352 ! cell fate determination GO:0001709 45 23 1,000 5,787E-03 0,06022975 ! protein import into nucleus GO:0006606 118 74 2,000 5,983E-03 0,06198602 ! regulation of ligase activity GO:0051340 114 75 2,000 6,21E-03 0,0640509 ! nuclear import GO:0051170 121 75 2,000 6,21E-03 0,06376496 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 6,293E-03 0,06432949 ! mitochondrial membrane organization GO:0007006 39 24 1,000 6,293E-03 0,06404485 ! negative regulation of cell development GO:0010721 56 24 1,000 6,293E-03 0,06376271 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 6,293E-03 0,06348305 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 6,293E-03 0,06320583 ! regulation of DNA binding GO:0051101 119 77 2,000 6,68E-03 0,0667978 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 6,818E-03 0,06788816 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 6,818E-03 0,06759554 ! male gonad development GO:0008584 33 25 1,000 6,818E-03 0,06730543 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 6,818E-03 0,0670178 ! T cell activation GO:0042110 134 79 2,000 7,17E-03 0,07017469 ! regulation of pH GO:0006885 36 26 1,000 7,363E-03 0,07175594 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 7,363E-03 0,07145318 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 7,423E-03 0,07173432 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 2,000 7,423E-03 0,07143417 ! regulation of cell cycle process GO:0010564 122 81 2,000 7,681E-03 0,07361049 ! inner ear morphogenesis GO:0042472 35 27 1,000 7,926E-03 0,07564477 ! response to ionizing radiation GO:0010212 47 27 1,000 7,926E-03 0,07533218 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 7,926E-03 0,07502217 GO:0043433|negative regulation of transcription factor activity, ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 8,487E-03 0,08000223 ! cell junction assembly GO:0034329 56 28 1,000 8,509E-03 0,07987619 ! erythrocyte differentiation GO:0030218 38 28 1,000 8,509E-03 0,07955149 ! positive regulation of catabolic process GO:0009896 40 28 1,000 8,509E-03 0,07922942 ! regulation of B cell activation GO:0050864 42 28 1,000 8,509E-03 0,07890994 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 8,767E-03 0,08097587 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 8,767E-03 0,08065197 ! cell cycle arrest GO:0007050 150 86 2,000 9,051E-03 0,08293921 ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 9,341E-03 0,08525732 ! spindle organization GO:0007051 37 30 1,000 9,729E-03 0,08844383 ! hindbrain development GO:0030902 45 30 1,000 9,729E-03 0,08809562 ! regulation of microtubule-based process GO:0032886 58 30 1,000 9,729E-03 0,08775015 ! reproductive developmental process GO:0003006 127 89 2,000 9,938E-03 0,0892824 ! segmentation GO:0035282 41 31 1,000 0,01036641 0,0927733 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,01036641 0,09241371 ! leukocyte chemotaxis GO:0030595 43 31 1,000 0,01036641 0,0920569 GO:0060326|cell chemotaxis, ! cell fate commitment GO:0045165 141 92 2,000 0,01087271 0,09618166 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,01102204 0,09712908 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,01102204 0,09675835 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,01102204 0,09639045 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,01102204 0,09602534 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 0,01119538 0,09716746 ! ear morphogenesis GO:0042471 42 33 1,000 0,01169552 0,10112669 ! cell junction organization GO:0034330 63 33 1,000 0,01169552 0,10074794 ! carbohydrate homeostasis GO:0033500 39 33 1,000 0,01169552 0,10037202 GO:0042593|glucose homeostasis, ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,01169552 0,09999889 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,01169552 0,09962852 ! regulation of binding GO:0051098 151 95 2,000 0,01185724 0,10063338 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 0,01219645 0,10313176 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,01238667 0,10435655 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 0,01238667 0,10397569 ! erythrocyte homeostasis GO:0034101 45 34 1,000 0,01238667 0,10359759 ! polyol metabolic process GO:0019751 44 34 1,000 0,01238667 0,10322224 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 0,01238667 0,10284959 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,01309529 0,10834233 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein import GO:0017038 156 99 2,000 0,01324741 0,10920804 ! protein localization in organelle GO:0033365 161 100 2,000 0,01360888 0,11178721 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,0138212 0,11312725 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 0,0138212 0,11272609 ! neural tube development GO:0021915 50 36 1,000 0,0138212 0,11232777 ! gliogenesis GO:0042063 71 38 1,000 0,01532414 0,12410396 ! monocarboxylic acid transport GO:0015718 62 38 1,000 0,01532414 0,12366851 ! pigmentation GO:0043473 74 38 1,000 0,01532414 0,1232361 ! male sex differentiation GO:0046661 53 39 1,000 0,01610081 0,12903085 ! inner ear development GO:0048839 57 40 1,000 0,01689403 0,13491757 ! T cell differentiation GO:0030217 65 40 1,000 0,01689403 0,13445073 ! B cell differentiation GO:0030183 62 40 1,000 0,01689403 0,13398711 ! glucose transport GO:0015758 52 41 1,000 0,01770362 0,13992553 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,01770362 0,13944633 ! mitochondrial transport GO:0006839 60 42 1,000 0,01852941 0,14545271 ! hexose transport GO:0008645 54 42 1,000 0,01852941 0,14495797 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 1,000 0,01852941 0,14446659 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,01852941 0,14397853 ! positive regulation of binding GO:0051099 59 43 1,000 0,01937122 0,1500128 ! leukocyte migration GO:0050900 60 43 1,000 0,01937122 0,14950941 ! activation of caspase activity GO:0006919 65 43 1,000 0,01937122 0,14900937 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,01937122 0,14851268 ! cellular amino acid biosynthetic process GO:0008652 51 44 1,000 0,02022887 0,15457275 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,02022887 0,15406092 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,02022887 0,15355247 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,02110219 0,1596547 ! regulation of ossification GO:0030278 71 46 1,000 0,021991 0,16583376 ! histone modification GO:0016570 68 46 1,000 0,021991 0,16529182 ! response to estrogen stimulus GO:0043627 74 47 1,000 0,02289513 0,17152706 ! endocrine system development GO:0035270 83 47 1,000 0,02289513 0,17097015 ! covalent chromatin modification GO:0016569 75 47 1,000 0,02289513 0,17041685 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,02289513 0,16986712 ! glutamine family amino acid metabolic process GO:0009064 59 47 1,000 0,02289513 0,16932092 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 0,02289513 0,16877823 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,02289513 0,168239 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,02381442 0,17443683 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 65 48 1,000 0,02381442 0,17388306 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,0246391 0,1793352 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,0246391 0,17876947 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,0246391 0,1782073 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,0246391 0,17764866 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,0246391 0,17709351 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0246391 0,17654181 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,0246391 0,17599355 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,0246391 0,17544868 ! sleep GO:0030431 11 5 0,000 0,0246391 0,17490717 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0246391 0,17436899 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,0246391 0,17383412 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,0246391 0,17330251 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,0246391 0,17277415 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,0246391 0,172249 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,0246391 0,17172704 ! tongue development GO:0043586 6 5 0,000 0,0246391 0,17120822 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,0246391 0,17069254 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0246391 0,17017995 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,0246391 0,16967043 ! cobalt ion transport GO:0006824 9 5 0,000 0,0246391 0,16916395 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,0246391 0,16866048 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,0246391 0,16816001 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,0246391 0,16766249 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,0246391 0,16716791 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,0246391 0,16667624 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,0246391 0,16618746 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,0246391 0,16570153 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,0246391 0,16521843 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,0246391 0,16473815 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0246391 0,16426064 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0246391 0,1637859 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,0246391 0,1633139 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0246391 0,1628446 ! malate metabolic process GO:0006108 7 5 0,000 0,0246391 0,162378 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,0246391 0,16191406 ! behavioral response to pain GO:0048266 7 5 0,000 0,0246391 0,16145277 ! clathrin coat assembly GO:0048268 11 5 0,000 0,0246391 0,1609941 ! phototransduction, visible light GO:0007603 6 5 0,000 0,0246391 0,16053802 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0246391 0,16008453 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,0246391 0,15963358 ! mating behavior GO:0007617 6 5 0,000 0,0246391 0,15918517 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0246391 0,15873928 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,0246391 0,15829587 ! rhythmic behavior GO:0007622 12 5 0,000 0,0246391 0,15785494 ! copulation GO:0007620 7 5 0,000 0,0246391 0,15741645 ! glial cell fate commitment GO:0021781 12 5 0,000 0,0246391 0,15698039 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,0246391 0,15654675 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,0246391 0,15611549 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,0246391 0,1556866 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,0246391 0,15526006 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,0246391 0,15483585 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,0246391 0,15441396 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,0246391 0,15399435 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0246391 0,15357703 ! response to protozoan GO:0001562 9 5 0,000 0,0246391 0,15316195 ! lymph vessel development GO:0001945 7 5 0,000 0,0246391 0,15274912 ! endochondral ossification GO:0001958 12 5 0,000 0,0246391 0,1523385 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,0246391 0,15193009 ! parathyroid gland development GO:0060017 8 5 0,000 0,0246391 0,15152386 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,0246391 0,15111979 ! anagen GO:0042640 6 5 0,000 0,0246391 0,15071788 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,0246391 0,1503181 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,0246391 0,14992043 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,0246391 0,14952486 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,0246391 0,14913137 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,0246391 0,14873995 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,0246391 0,14835058 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,0246391 0,14796324 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,0246391 0,14757792 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,0246391 0,1471946 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,0246391 0,14681327 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,0246391 0,14643391 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,0246391 0,1460565 ! ovulation GO:0030728 6 5 0,000 0,0246391 0,14568103 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,0246391 0,14530749 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,0246391 0,14493586 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,0246391 0,14456613 ! response to pH GO:0009268 9 5 0,000 0,0246391 0,14419828 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,0246391 0,14383229 ! proline biosynthetic process GO:0006561 6 5 0,000 0,0246391 0,14346816 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0246391 0,14310586 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,0246391 0,1427454 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0246391 0,14238674 ! polyol catabolic process GO:0046174 7 5 0,000 0,0246391 0,14202988 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0246391 0,14167481 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0246391 0,1413215 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0246391 0,14096996 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,0246391 0,14062015 ! nerve growth factor processing GO:0032455 7 5 0,000 0,0246391 0,14027208 ! urea metabolic process GO:0019627 6 5 0,000 0,0246391 0,13992573 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,0246391 0,13958109 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0246391 0,13923814 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,0246391 0,13889687 ! neutrophil activation GO:0042119 5 5 0,000 0,0246391 0,13855727 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,0246391 0,13821932 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,0246391 0,13788302 ! response to food GO:0032094 5 5 0,000 0,0246391 0,13754835 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,0246391 0,13721531 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0246391 0,13688387 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,0246391 0,13655403 ! forebrain neuron development GO:0021884 7 5 0,000 0,0246391 0,13622577 ! melanosome organization GO:0032438 7 5 0,000 0,0246391 0,13589909 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,0246391 0,13557398 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0246391 0,13525041 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,0246391 0,13492839 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0246391 0,13460789 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,0246391 0,13428892 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,0246391 0,13397145 ! nucleoside transport GO:0015858 6 5 0,000 0,0246391 0,13365548 ! nucleoside salvage GO:0043174 7 5 0,000 0,0246391 0,13334099 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,0246391 0,13302799 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0246391 0,13271645 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,0246391 0,13240636 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,0246391 0,13209772 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0246391 0,13179052 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,0246391 0,13148474 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0246391 0,13118038 ! depyrimidination GO:0045008 8 5 0,000 0,0246391 0,13087742 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,0246391 0,13057586 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,0246391 0,13027568 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,0246391 0,12997689 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,0246391 0,12967946 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,0246391 0,12938338 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,0246391 0,12908866 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,0246391 0,12879528 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,0246391 0,12850323 ! monocyte differentiation GO:0030224 8 5 0,000 0,0246391 0,12821249 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,0246391 0,12792308 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0246391 0,12763496 ! centrosome duplication GO:0051298 5 5 0,000 0,0246391 0,12734814 ! response to UV-C GO:0010225 6 5 0,000 0,0246391 0,12706261 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,0246391 0,12677835 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,0246391 0,12649536 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,0246391 0,12621364 ! regulation of dendrite development GO:0050773 12 5 0,000 0,0246391 0,12593316 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,0246391 0,12565393 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0246391 0,12537593 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,0246391 0,12509917 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,0246391 0,12482362 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,0246391 0,12454928 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,0246391 0,12427615 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,0246391 0,12400421 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,0246391 0,12373345 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,0246391 0,12346388 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0246391 0,12319548 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,0246391 0,12292825 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0246391 0,12266217 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0246391 0,12239724 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,0246391 0,12213345 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,0246391 0,1218708 ! histone demethylation GO:0016577 9 5 0,000 0,0246391 0,12160928 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0246391 0,12134887 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0246391 0,12108958 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,0246391 0,12083139 ! enteric nervous system development GO:0048484 8 5 0,000 0,0246391 0,1205743 ! establishment of planar polarity GO:0001736 6 5 0,000 0,0246391 0,12031831 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,0246391 0,12006339 ! muscle cell proliferation GO:0033002 8 5 0,000 0,0246391 0,11980956 ! transcription termination GO:0006353 8 5 0,000 0,0246391 0,1195568 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,0246391 0,1193051 ! plasminogen activation GO:0031639 5 5 0,000 0,0246391 0,11905446 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,0246391 0,11880487 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0246391 0,11855632 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0246391 0,11830881 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,0246391 0,11806234 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,0246391 0,11781689 ! apical protein localization GO:0045176 6 5 0,000 0,0246391 0,11757245 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,0246391 0,11732903 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0246391 0,11708662 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0246391 0,1168452 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,0246391 0,11660478 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,0246391 0,11636534 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,0246391 0,11612689 ! glial cell migration GO:0008347 10 5 0,000 0,0246391 0,11588941 ! determination of adult lifespan GO:0008340 8 5 0,000 0,0246391 0,1156529 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,0246391 0,11541736 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0246391 0,11518277 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0246391 0,11494913 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,0246391 0,11471644 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,0246391 0,11448469 ! neural plate development GO:0001840 6 5 0,000 0,0246391 0,11425388 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,0246391 0,11402399 ! regulation of sensory perception GO:0051931 6 5 0,000 0,0246391 0,11379502 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,0246391 0,11356698 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,0246391 0,11333984 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,0246391 0,11311362 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,0246391 0,11288829 ! sensory cilium assembly GO:0035058 6 5 0,000 0,0246391 0,11266386 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,0246391 0,11244032 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0246391 0,11221767 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,0246391 0,11199589 ! spindle assembly GO:0051225 5 5 0,000 0,0246391 0,11177499 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,0246391 0,11155497 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,0246391 0,1113358 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,0246391 0,11111749 ! organ regeneration GO:0031100 7 5 0,000 0,0246391 0,11090004 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,0246391 0,11068344 ! carnitine metabolic process GO:0009437 5 5 0,000 0,0246391 0,11046768 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,0246391 0,11025277 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,0246391 0,11003868 GO:0055081|anion homeostasis, ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,02474869 0,11031391 ! germ cell development GO:0007281 68 49 1,000 0,02474869 0,11010054 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,02474869 0,10988799 ! ear development GO:0043583 72 50 1,000 0,02569777 0,11388221 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,02569777 0,11366321 ! lipid modification GO:0030258 73 50 1,000 0,02569777 0,11344504 ! positive regulation of growth GO:0045927 67 50 1,000 0,02569777 0,11322771 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,0266615 0,11724941 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cell motion GO:0051271 104 51 1,000 0,0266615 0,11702565 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,02763971 0,12108823 ! aging GO:0007568 79 52 1,000 0,02763971 0,12085803 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,02763971 0,1206287 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,02863223 0,12472373 ! tRNA transcription GO:0009304 11 6 0,000 0,02949441 0,12823659 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02949441 0,12799463 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02949441 0,12775359 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02949441 0,12751345 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02949441 0,12727421 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02949441 0,12703587 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02949441 0,12679842 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02949441 0,12656186 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02949441 0,12632617 ! prostate gland development GO:0030850 9 6 0,000 0,02949441 0,12609137 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02949441 0,12585743 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02949441 0,12562436 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02949441 0,12539215 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02949441 0,1251608 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02949441 0,1249303 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02949441 0,12470065 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02949441 0,12447184 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02949441 0,12424387 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02949441 0,12401674 ! neuron adhesion GO:0007158 9 6 0,000 0,02949441 0,12379043 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02949441 0,12356494 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02949441 0,12334028 ! signal peptide processing GO:0006465 8 6 0,000 0,02949441 0,12311643 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02949441 0,1228934 ! mRNA stabilization GO:0048255 15 6 0,000 0,02949441 0,12267117 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02949441 0,12244974 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02949441 0,12222911 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02949441 0,12200927 ! opsonization GO:0008228 8 6 0,000 0,02949441 0,12179022 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02949441 0,12157196 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02949441 0,12135448 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02949441 0,12113778 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02949441 0,12092184 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02949441 0,12070668 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02949441 0,12049228 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02949441 0,12027864 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02949441 0,12006576 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02949441 0,11985363 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02949441 0,11964225 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02949441 0,11943161 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02949441 0,11922171 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02949441 0,11901255 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02949441 0,11880412 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02949441 0,11859642 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02949441 0,11838945 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02949441 0,1181832 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02949441 0,11797766 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02949441 0,11777284 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02949441 0,11756873 ! thymic T cell selection GO:0045061 12 6 0,000 0,02949441 0,11736532 ! protein lipoylation GO:0009249 10 6 0,000 0,02949441 0,11716262 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02949441 0,11696061 ! pigment granule organization GO:0048753 11 6 0,000 0,02949441 0,1167593 ! drug transport GO:0015893 6 6 0,000 0,02949441 0,11655868 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02949441 0,11635876 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02949441 0,11615951 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02949441 0,11596095 ! histidine metabolic process GO:0006547 6 6 0,000 0,02949441 0,11576306 GO:0009075|histidine family amino acid metabolic process, ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02949441 0,11556585 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02949441 0,11536931 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02949441 0,11517344 ! adenohypophysis development GO:0021984 10 6 0,000 0,02949441 0,11497823 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02949441 0,11478368 ! hyperosmotic response GO:0006972 8 6 0,000 0,02949441 0,11458979 ! microtubule nucleation GO:0007020 10 6 0,000 0,02949441 0,11439655 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02949441 0,11420396 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02949441 0,11401202 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02949441 0,11382073 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02949441 0,11363007 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02949441 0,11344006 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02949441 0,11325068 ! response to dietary excess GO:0002021 7 6 0,000 0,02949441 0,11306192 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02949441 0,1128738 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02949441 0,1126863 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02949441 0,11249943 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02949441 0,11231317 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02949441 0,11212753 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02949441 0,1119425 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02949441 0,11175808 ! neuron apoptosis GO:0051402 8 6 0,000 0,02949441 0,11157427 ! organic alcohol transport GO:0015850 9 6 0,000 0,02949441 0,11139106 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02949441 0,11120845 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02949441 0,11102644 ! carnitine transport GO:0015879 8 6 0,000 0,02949441 0,11084502 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02949441 0,1106642 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02949441 0,11048396 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02949441 0,11030432 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02949441 0,11012525 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02949441 0,10994677 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02949441 0,10976886 ! parturition GO:0007567 12 6 0,000 0,02949441 0,10959153 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02949441 0,10941477 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02949441 0,10923857 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02949441 0,10906295 ! spindle checkpoint GO:0031577 14 6 0,000 0,02949441 0,10888789 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02949441 0,10871339 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02949441 0,10853945 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02949441 0,10836606 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02949441 0,10819323 ! astrocyte development GO:0014002 14 6 0,000 0,02949441 0,10802095 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02949441 0,10784921 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02949441 0,10767802 ! interaction with symbiont GO:0051702 8 6 0,000 0,02949441 0,10750738 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02949441 0,10733727 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02949441 0,1071677 ! eating behavior GO:0042755 6 6 0,000 0,02949441 0,10699867 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02949441 0,10683016 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02949441 0,10666219 ! response to copper ion GO:0046688 9 6 0,000 0,02949441 0,10649475 ! DNA topological change GO:0006265 8 6 0,000 0,02949441 0,10632783 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02949441 0,10616143 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02949441 0,10599555 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02949441 0,10583019 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02949441 0,10566535 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02949441 0,10550102 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02949441 0,1053372 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02949441 0,10517388 ! gas homeostasis GO:0033483 11 6 0,000 0,02949441 0,10501107 ! hair follicle maturation GO:0048820 7 6 0,000 0,02949441 0,10484877 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02949441 0,10468697 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02949441 0,10452566 ! Schwann cell development GO:0014044 14 6 0,000 0,02949441 0,10436485 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02949441 0,10420454 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02949441 0,10404472 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02949441 0,10388538 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02949441 0,10372654 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02949441 0,10356817 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02949441 0,1034103 ! histone ubiquitination GO:0016574 7 6 0,000 0,02949441 0,1032529 ! regulation of meiosis GO:0040020 10 6 0,000 0,02949441 0,10309598 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02949441 0,10293954 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02949441 0,10278357 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02949441 0,10262807 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02949441 0,10247304 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02949441 0,10231848 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02949441 0,10216439 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02949441 0,10201076 ! receptor internalization GO:0031623 9 6 0,000 0,02949441 0,10185759 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02949441 0,10170488 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02949441 0,10155263 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02949441 0,10140083 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02949441 0,10124948 ! protein deubiquitination GO:0016579 8 6 0,000 0,02949441 0,10109859 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02949441 0,10094815 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02949441 0,10079815 ! axonal fasciculation GO:0007413 9 6 0,000 0,02949441 0,1006486 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02949441 0,10049949 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02949441 0,10035082 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02949441 0,10020259 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02949441 0,1000548 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02949441 0,09990744 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02949441 0,09976052 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02949441 0,09961403 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02949441 0,09946797 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02949441 0,09932233 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02949441 0,09917713 ! adult feeding behavior GO:0008343 6 6 0,000 0,02949441 0,09903234 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02949441 0,09888798 ! blastocyst growth GO:0001832 15 6 0,000 0,02949441 0,09874404 ! pigment granule transport GO:0051904 12 6 0,000 0,02949441 0,09860052 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02949441 0,09845741 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02949441 0,09831472 ! catecholamine transport GO:0051937 7 6 0,000 0,02949441 0,09817244 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02949441 0,09803057 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02949441 0,09788911 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02949441 0,09774806 ! protein prenylation GO:0018342 10 6 0,000 0,02949441 0,09760742 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02949441 0,09746718 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,02949441 0,09732734 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02949441 0,0971879 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02949441 0,09704886 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02949441 0,09691022 ! regulation of mitosis GO:0007088 84 54 1,000 0,02963891 0,09724607 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,02963891 0,09710754 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,02963891 0,09696941 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,02963891 0,09683167 ! cellular amino acid catabolic process GO:0009063 74 54 1,000 0,02963891 0,09669432 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,02963891 0,09655736 ! carbohydrate transport GO:0008643 74 57 1,000 0,03274226 0,10651653 ! chromosome segregation GO:0007059 83 57 1,000 0,03274226 0,10636609 ! gonad development GO:0008406 79 57 1,000 0,03274226 0,10621606 ! viral reproductive process GO:0022415 87 58 1,000 0,03380394 0,10950573 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,03432584 0,11103999 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03432584 0,11088403 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03432584 0,11072852 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03432584 0,11057343 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03432584 0,11041879 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,03432584 0,11026457 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03432584 0,11011078 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,03432584 0,10995743 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03432584 0,1098045 ! reproductive behavior GO:0019098 12 7 0,000 0,03432584 0,10965199 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03432584 0,10949991 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,03432584 0,10934824 ! oligopeptide transport GO:0006857 11 7 0,000 0,03432584 0,109197 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03432584 0,10904618 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03432584 0,10889577 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,03432584 0,10874577 ! RNA methylation GO:0001510 11 7 0,000 0,03432584 0,10859619 ! pericardium development GO:0060039 8 7 0,000 0,03432584 0,10844702 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03432584 0,10829826 ! fibril organization GO:0043206 13 7 0,000 0,03432584 0,10814991 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03432584 0,10800196 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,03432584 0,10785442 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03432584 0,10770727 ! lipoprotein transport GO:0042953 9 7 0,000 0,03432584 0,10756053 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03432584 0,10741419 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03432584 0,10726825 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03432584 0,1071227 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03432584 0,10697755 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03432584 0,10683279 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03432584 0,10668842 ! chemosensory behavior GO:0007635 9 7 0,000 0,03432584 0,10654444 ! microtubule bundle formation GO:0001578 8 7 0,000 0,03432584 0,10640085 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,03432584 0,10625765 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03432584 0,10611483 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03432584 0,10597239 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03432584 0,10583034 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03432584 0,10568866 ! reflex GO:0060004 12 7 0,000 0,03432584 0,10554737 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03432584 0,10540645 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03432584 0,10526591 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03432584 0,10512574 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03432584 0,10498595 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,03432584 0,10484652 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03432584 0,10470747 ! spinal cord patterning GO:0021511 7 7 0,000 0,03432584 0,10456878 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,03432584 0,10443047 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,03432584 0,10429251 ! adrenal gland development GO:0030325 17 7 0,000 0,03432584 0,10415492 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03432584 0,1040177 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03432584 0,10388083 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03432584 0,10374433 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03432584 0,10360818 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03432584 0,10347239 ! endosome organization GO:0007032 10 7 0,000 0,03432584 0,10333695 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03432584 0,10320187 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03432584 0,10306714 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03432584 0,10293277 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03432584 0,10279874 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03432584 0,10266506 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,03432584 0,10253173 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03432584 0,10239874 ! galactose metabolic process GO:0006012 10 7 0,000 0,03432584 0,1022661 ! vesicle fusion GO:0006906 15 7 0,000 0,03432584 0,10213381 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03432584 0,10200185 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,03432584 0,10187024 ! organ growth GO:0035265 11 7 0,000 0,03432584 0,10173896 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03432584 0,10160802 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,03432584 0,10147742 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03432584 0,10134715 ! retinol metabolic process GO:0042572 9 7 0,000 0,03432584 0,10121722 ! behavioral fear response GO:0001662 13 7 0,000 0,03432584 0,10108762 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,03432584 0,10095835 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03432584 0,10082942 ! rRNA modification GO:0000154 12 7 0,000 0,03432584 0,10070081 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03432584 0,10057253 ! response to UV-B GO:0010224 11 7 0,000 0,03432584 0,10044457 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03432584 0,10031694 ! intermediate filament organization GO:0045109 11 7 0,000 0,03432584 0,10018963 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,03432584 0,10006265 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03432584 0,09993599 ! fibrinolysis GO:0042730 9 7 0,000 0,03432584 0,09980965 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,03432584 0,09968363 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03432584 0,09955792 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03432584 0,09943253 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03432584 0,09930746 ! response to tropane GO:0014073 13 7 0,000 0,03432584 0,0991827 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,03432584 0,09905826 ! melanosome localization GO:0032400 10 7 0,000 0,03432584 0,09893413 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03432584 0,0988103 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03432584 0,09868679 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03432584 0,09856359 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03432584 0,09844069 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03432584 0,0983181 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03432584 0,09819581 ! mast cell activation GO:0045576 9 7 0,000 0,03432584 0,09807383 ! multicellular organismal aging GO:0010259 11 7 0,000 0,03432584 0,09795215 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,03432584 0,09783077 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03432584 0,09770969 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03432584 0,09758892 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,03432584 0,09746843 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,03432584 0,09734825 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03432584 0,09722836 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,03432584 0,09710877 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03432584 0,09698947 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03432584 0,09687047 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03432584 0,09675176 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03432584 0,09663333 ! neuroblast proliferation GO:0007405 13 7 0,000 0,03432584 0,0965152 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03432584 0,09639735 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,03432584 0,0962798 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,03432584 0,09616252 ! diuresis GO:0030146 12 7 0,000 0,03432584 0,09604554 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03432584 0,09592884 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03432584 0,09581242 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03432584 0,09569628 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03432584 0,09558043 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03432584 0,09546485 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03432584 0,09534956 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03432584 0,09523454 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03432584 0,0951198 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03432584 0,09500533 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03432584 0,09489114 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03432584 0,09477723 ! lymph node development GO:0048535 9 7 0,000 0,03432584 0,09466359 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,03432584 0,09455022 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,03432584 0,09443712 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03432584 0,09432429 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,03432584 0,09421173 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03432584 0,09409944 ! ATP catabolic process GO:0006200 10 7 0,000 0,03432584 0,09398742 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03432584 0,09387566 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,03432584 0,09376417 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03432584 0,09365294 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03432584 0,09354198 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03432584 0,09343128 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03432584 0,09332084 ! muscle adaptation GO:0043500 12 7 0,000 0,03432584 0,09321066 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03432584 0,09310075 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03432584 0,09299109 ! retina homeostasis GO:0001895 9 7 0,000 0,03432584 0,09288169 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03432584 0,09277254 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,03432584 0,09266365 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,03432584 0,09255502 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03432584 0,09244664 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03432584 0,09233852 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03432584 0,09223065 ! activation of MAPK activity GO:0000187 84 59 1,000 0,03487898 0,09360754 ! lung development GO:0030324 94 59 1,000 0,03487898 0,09349844 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,03596723 0,0963034 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,03596723 0,09619142 GO:0035113|embryonic appendage morphogenesis, ! regulation of homeostatic process GO:0032844 105 60 1,000 0,03596723 0,0960797 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,03706851 0,09890671 ! meiosis GO:0007126 96 61 1,000 0,03706851 0,0987921 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 1,000 0,03706851 0,09867776 ! homeostasis of number of cells GO:0048872 84 61 1,000 0,03706851 0,09856368 ! amine catabolic process GO:0009310 90 62 1,000 0,03818269 0,101409 ! respiratory tube development GO:0030323 99 62 1,000 0,03818269 0,10129203 ! meiotic cell cycle GO:0051321 97 62 1,000 0,03818269 0,10117534 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03913349 0,1035754 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03913349 0,10345635 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,03913349 0,10333757 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03913349 0,10321906 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03913349 0,10310083 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03913349 0,10298286 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03913349 0,10286517 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03913349 0,10274774 ! phosphate transport GO:0006817 10 8 0,000 0,03913349 0,10263059 ! N-glycan processing GO:0006491 12 8 0,000 0,03913349 0,10251369 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03913349 0,10239707 ! UTP metabolic process GO:0046051 8 8 0,000 0,03913349 0,10228071 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03913349 0,10216461 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03913349 0,10204878 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,03913349 0,10193321 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03913349 0,1018179 ! succinate metabolic process GO:0006105 14 8 0,000 0,03913349 0,10170285 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,03913349 0,10158806 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03913349 0,10147353 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03913349 0,10135926 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,03913349 0,10124525 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,03913349 0,10113149 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,03913349 0,10101798 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03913349 0,10090473 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03913349 0,10079174 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03913349 0,100679 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03913349 0,10056651 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03913349 0,10045427 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,03913349 0,10034228 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03913349 0,10023054 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03913349 0,10011905 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03913349 0,1000078 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03913349 0,09989681 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,03913349 0,09978606 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03913349 0,09967555 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03913349 0,09956529 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03913349 0,09945527 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03913349 0,0993455 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,03913349 0,09923597 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03913349 0,09912668 ! melanin metabolic process GO:0006582 12 8 0,000 0,03913349 0,09901763 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03913349 0,09890882 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03913349 0,09880024 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,03913349 0,09869191 ! macrophage activation GO:0042116 12 8 0,000 0,03913349 0,09858381 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03913349 0,09847596 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03913349 0,09836833 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03913349 0,09826094 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03913349 0,09815379 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03913349 0,09804687 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,03913349 0,09794018 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03913349 0,09783372 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03913349 0,0977275 ! ruffle organization GO:0031529 11 8 0,000 0,03913349 0,0976215 ! osteoblast development GO:0002076 13 8 0,000 0,03913349 0,09751573 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,03913349 0,0974102 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03913349 0,09730489 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03913349 0,09719981 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03913349 0,09709495 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,03913349 0,09699033 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03913349 0,09688592 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03913349 0,09678175 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03913349 0,09667779 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03913349 0,09657406 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,03913349 0,09647055 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,03913349 0,09636726 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03913349 0,0962642 ! segment specification GO:0007379 10 8 0,000 0,03913349 0,09616135 ! cellular extravasation GO:0045123 11 8 0,000 0,03913349 0,09605872 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03913349 0,09595631 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,03913349 0,09585412 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03913349 0,09575215 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,03913349 0,0956504 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03913349 0,09554886 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03913349 0,09544753 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03913349 0,09534642 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03913349 0,09524553 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03913349 0,09514484 ! nucleosome disassembly GO:0006337 12 8 0,000 0,03913349 0,09504437 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03913349 0,09494412 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03913349 0,09484407 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03913349 0,09474423 ! icosanoid secretion GO:0032309 12 8 0,000 0,03913349 0,09464461 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,03913349 0,09454519 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03913349 0,09444598 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03913349 0,09434698 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03913349 0,09424819 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03913349 0,09414961 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03913349 0,09405123 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03913349 0,09395305 ! sterol catabolic process GO:0016127 9 8 0,000 0,03913349 0,09385508 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03913349 0,09375732 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03913349 0,09365975 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03913349 0,09356239 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03913349 0,09346524 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03913349 0,09336828 ! prophase GO:0051324 11 8 0,000 0,03913349 0,09327153 ! S phase GO:0051320 8 8 0,000 0,03913349 0,09317497 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03913349 0,09307862 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03913349 0,09298246 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03913349 0,0928865 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03913349 0,09279075 ! hormone catabolic process GO:0042447 13 8 0,000 0,03913349 0,09269518 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03913349 0,09259982 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03913349 0,09250465 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03913349 0,09240967 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03913349 0,0923149 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03913349 0,09222031 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,03913349 0,09212592 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03913349 0,09203172 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03913349 0,09193772 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03913349 0,0918439 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03913349 0,09175028 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03913349 0,09165685 ! lamellipodium assembly GO:0030032 9 8 0,000 0,03913349 0,0915636 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03913349 0,09147055 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,03913349 0,09137769 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,03913349 0,09128501 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,03930961 0,09160294 ! viral reproduction GO:0016032 92 63 1,000 0,03930961 0,09151023 ! regulation of lipase activity GO:0060191 109 63 1,000 0,03930961 0,0914177 ! appendage morphogenesis GO:0035107 93 64 1,000 0,04044912 0,0939727 GO:0035108|limb morphogenesis, ! respiratory system development GO:0060541 100 64 1,000 0,04044912 0,09387787 ! reproductive structure development GO:0048608 90 65 1,000 0,04160106 0,09645408 ! regulation of caspase activity GO:0043281 97 65 1,000 0,04160106 0,09635695 ! appendage development GO:0048736 94 65 1,000 0,04160106 0,09626001 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 1,000 0,04160106 0,09616326 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,0427653 0,09875521 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,04391748 0,10131414 ! telencephalon cell migration GO:0022029 16 9 0,000 0,04391748 0,10121262 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,04391748 0,1011113 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,04391748 0,10101019 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,04391748 0,10090928 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,04391748 0,10080858 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04391748 0,10070807 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,04391748 0,10060776 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,04391748 0,10050765 ! GTP metabolic process GO:0046039 9 9 0,000 0,04391748 0,10040775 ! elastic fiber assembly GO:0048251 13 9 0,000 0,04391748 0,10030804 ! social behavior GO:0035176 14 9 0,000 0,04391748 0,10020852 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,04391748 0,10010921 ! artery development GO:0060840 19 9 0,000 0,04391748 0,10001009 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,04391748 0,09991117 ! response to pain GO:0048265 16 9 0,000 0,04391748 0,09981244 ! protein complex disassembly GO:0043241 17 9 0,000 0,04391748 0,09971391 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,04391748 0,09961557 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,04391748 0,09951743 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,04391748 0,09941948 ! lung alveolus development GO:0048286 17 9 0,000 0,04391748 0,09932172 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,04391748 0,09922416 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,04391748 0,09912678 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,04391748 0,0990296 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,04391748 0,09893261 ! ventral spinal cord development GO:0021517 11 9 0,000 0,04391748 0,09883581 ! protein targeting to ER GO:0045047 19 9 0,000 0,04391748 0,09873919 ! T cell selection GO:0045058 18 9 0,000 0,04391748 0,09864277 ! endoderm development GO:0007492 12 9 0,000 0,04391748 0,09854653 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,04391748 0,09845048 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,04391748 0,09835462 ! arginine catabolic process GO:0006527 10 9 0,000 0,04391748 0,09825894 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,04391748 0,09816345 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,04391748 0,09806815 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,04391748 0,09797303 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04391748 0,09787809 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,04391748 0,09778334 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,04391748 0,09768877 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,04391748 0,09759439 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,04391748 0,09750019 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04391748 0,09740616 ! mannose metabolic process GO:0006013 9 9 0,000 0,04391748 0,09731232 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,04391748 0,09721866 ! receptor clustering GO:0043113 15 9 0,000 0,04391748 0,09712519 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,04391748 0,09703189 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,04391748 0,09693876 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,04391748 0,09684582 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,04391748 0,09675306 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,04391748 0,09666047 ! motor axon guidance GO:0008045 14 9 0,000 0,04391748 0,09656806 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,04391748 0,09647583 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,04391748 0,09638377 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,04391748 0,09629189 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,04391748 0,09620018 ! blastoderm segmentation GO:0007350 11 9 0,000 0,04391748 0,09610865 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,04391748 0,09601729 ! DNA ligation GO:0006266 14 9 0,000 0,04391748 0,09592611 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,04391748 0,0958351 ! response to amine stimulus GO:0014075 13 9 0,000 0,04391748 0,09574426 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,04391748 0,09565359 ! erythrocyte development GO:0048821 11 9 0,000 0,04391748 0,0955631 ! renal water homeostasis GO:0003091 14 9 0,000 0,04391748 0,09547277 ! mRNA cleavage GO:0006379 13 9 0,000 0,04391748 0,09538262 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,04391748 0,09529263 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,04391748 0,09520282 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,04391748 0,09511318 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,04391748 0,0950237 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,04391748 0,09493439 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,04391748 0,09484525 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,04391748 0,09475628 ! acid secretion GO:0046717 14 9 0,000 0,04391748 0,09466747 ! musculoskeletal movement GO:0050881 11 9 0,000 0,04391748 0,09457883 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,04391748 0,09449036 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,04391748 0,09440205 ! purine base metabolic process GO:0006144 18 9 0,000 0,04391748 0,09431391 ! oocyte differentiation GO:0009994 12 9 0,000 0,04391748 0,09422593 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,04391748 0,09413811 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,04391748 0,09405046 ! spleen development GO:0048536 15 9 0,000 0,04391748 0,09396297 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,04391748 0,09387564 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,04391748 0,09378848 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,04391748 0,09370148 ! detection of calcium ion GO:0005513 13 9 0,000 0,04391748 0,09361464 ! blastocyst formation GO:0001825 12 9 0,000 0,04391748 0,09352796 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,04391748 0,09344144 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,04391748 0,09335508 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,04391748 0,09326888 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,04391748 0,09318283 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04391748 0,09309695 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,04391748 0,09301123 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,04391748 0,09292566 ! prepulse inhibition GO:0060134 14 9 0,000 0,04391748 0,09284025 ! embryonic placenta development GO:0001892 12 9 0,000 0,04391748 0,092755 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,04391748 0,0926699 ! insulin secretion GO:0030073 17 9 0,000 0,04391748 0,09258496 ! sequestering of metal ion GO:0051238 11 9 0,000 0,04391748 0,09250018 ! response to nicotine GO:0035094 16 9 0,000 0,04391748 0,09241555 ! establishment of cell polarity GO:0030010 12 9 0,000 0,04391748 0,09233107 ! regulation of synapse organization GO:0050807 12 9 0,000 0,04391748 0,09224675 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,04394168 0,09221337 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,04513005 0,09462088 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,04513005 0,09453471 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,0475422 0,09949686 ! regulation of catabolic process GO:0009894 106 70 1,000 0,0475422 0,09940641 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,04867792 0,10168865 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,04867792 0,10159638 ! neuron fate specification GO:0048665 11 10 0,000 0,04867792 0,10150427 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,04867792 0,10141232 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,04867792 0,10132055 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,04867792 0,10122894 ! synapsis GO:0007129 13 10 0,000 0,04867792 0,10113749 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,04867792 0,10104622 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,04867792 0,1009551 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,04867792 0,10086415 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,04867792 0,10077336 ! sulfate transport GO:0008272 12 10 0,000 0,04867792 0,10068274 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,04867792 0,10059228 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,04867792 0,10050198 ! phospholipid efflux GO:0033700 16 10 0,000 0,04867792 0,10041184 ! hippocampus development GO:0021766 19 10 0,000 0,04867792 0,10032187 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,04867792 0,10023206 ! blood vessel remodeling GO:0001974 21 10 0,000 0,04867792 0,1001424 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,04867792 0,10005291 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,04867792 0,09996358 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,04867792 0,0998744 GO:0010812|negative regulation of cell-substrate adhesion, ! pathogenesis GO:0009405 13 10 0,000 0,04867792 0,09978539 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,04867792 0,09969653 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04867792 0,09960783 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,04867792 0,09951929 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,04867792 0,09943091 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,04867792 0,09934269 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,04867792 0,09925462 ! melanocyte differentiation GO:0030318 15 10 0,000 0,04867792 0,0991667 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,04867792 0,09907894 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,04867792 0,09899134 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04867792 0,09890389 ! B cell proliferation GO:0042100 14 10 0,000 0,04867792 0,0988166 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,04867792 0,09872946 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,04867792 0,09864247 ! forebrain cell migration GO:0021885 17 10 0,000 0,04867792 0,09855564 ! lipid digestion GO:0044241 15 10 0,000 0,04867792 0,09846896 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,04867792 0,09838243 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,04867792 0,09829605 ! UV protection GO:0009650 14 10 0,000 0,04867792 0,09820983 ! entry into host cell GO:0030260 20 10 0,000 0,04867792 0,09812376 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,04867792 0,09803783 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,04867792 0,09795206 ! negative regulation of ossification GO:0030279 19 10 0,000 0,04867792 0,09786644 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,04867792 0,09778097 ! regulation of bone resorption GO:0045124 24 10 0,000 0,04867792 0,09769564 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,04867792 0,09761047 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,04867792 0,09752544 ! regulation of organ growth GO:0046620 11 10 0,000 0,04867792 0,09744056 ! response to dsRNA GO:0043331 18 10 0,000 0,04867792 0,09735583 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,04867792 0,09727125 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04867792 0,09718681 ! embryonic axis specification GO:0000578 12 10 0,000 0,04867792 0,09710252 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,04867792 0,09701838 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,04867792 0,09693438 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,04867792 0,09685052 ! cranial nerve development GO:0021545 12 10 0,000 0,04867792 0,09676682 ! fucose catabolic process GO:0019317 16 10 0,000 0,04867792 0,09668325 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,04867792 0,09659983 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,04867792 0,09651656 ! protein sumoylation GO:0016925 12 10 0,000 0,04867792 0,09643342 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,04867792 0,09635044 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04867792 0,09626759 ! zymogen activation GO:0031638 14 10 0,000 0,04867792 0,09618489 ! salivary gland development GO:0007431 22 10 0,000 0,04867792 0,09610232 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04867792 0,0960199 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,04867792 0,09593762 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,04867792 0,09585548 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,04867792 0,09577349 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,04867792 0,09569163 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,04867792 0,09560991 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04867792 0,09552833 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,04867792 0,09544689 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,04867792 0,09536559 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,04867792 0,09528443 ! detection of bacterium GO:0016045 10 10 0,000 0,04867792 0,09520341 ! embryonic gut development GO:0048566 11 10 0,000 0,04867792 0,09512252 ! activation of innate immune response GO:0002218 10 10 0,000 0,04867792 0,09504177 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,04867792 0,09496116 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,04867792 0,09488068 ! developmental induction GO:0031128 13 10 0,000 0,04867792 0,09480034 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,04867792 0,09472014 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,04867792 0,09464007 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,04867792 0,09456014 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,04867792 0,09448034 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,04876569 0,09457089 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,04876569 0,09449122 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,05000059 0,0968025 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,05000059 0,09672108 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 0,05000059 0,0966398 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,05000059 0,09655866 ! tube morphogenesis GO:0035239 118 73 1,000 0,05124678 0,09888221 ! mitochondrion organization GO:0007005 104 73 1,000 0,05124678 0,09879933 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,05124678 0,09871658 ! response to oxygen levels GO:0070482 137 74 1,000 0,05250411 0,10105394 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,05250411 0,10096944 ! rRNA transcription GO:0009303 17 11 0,000 0,05341492 0,10263519 ! respiratory burst GO:0045730 14 11 0,000 0,05341492 0,10254952 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,05341492 0,10246399 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,05341492 0,10237861 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,05341492 0,10229336 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,05341492 0,10220826 ! RNA polyadenylation GO:0043631 19 11 0,000 0,05341492 0,1021233 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,05341492 0,10203848 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,05341492 0,1019538 ! mating GO:0007618 14 11 0,000 0,05341492 0,10186926 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,05341492 0,10178486 ! T cell proliferation GO:0042098 20 11 0,000 0,05341492 0,1017006 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,05341492 0,10161648 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,05341492 0,1015325 ! bone resorption GO:0045453 16 11 0,000 0,05341492 0,10144866 ! regulated secretory pathway GO:0045055 14 11 0,000 0,05341492 0,10136496 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,05341492 0,10128139 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,05341492 0,10119796 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,05341492 0,10111467 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,05341492 0,10103152 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,05341492 0,1009485 ! syncytium formation GO:0006949 15 11 0,000 0,05341492 0,10086562 ! plasma membrane organization GO:0007009 18 11 0,000 0,05341492 0,10078288 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,05341492 0,10070027 ! mitotic spindle organization GO:0007052 15 11 0,000 0,05341492 0,10061779 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,05341492 0,10053546 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,05341492 0,10045325 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,05341492 0,10037118 ! adult heart development GO:0007512 11 11 0,000 0,05341492 0,10028925 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,05341492 0,10020744 ! temperature homeostasis GO:0001659 16 11 0,000 0,05341492 0,10012578 ! L-glutamate transport GO:0015813 16 11 0,000 0,05341492 0,10004424 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,05341492 0,09996284 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,05341492 0,09988157 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,05341492 0,09980043 ! stem cell development GO:0048864 29 11 0,000 0,05341492 0,09971942 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,05341492 0,09963855 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,05341492 0,0995578 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,05341492 0,09947719 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,05341492 0,0993967 ! vasoconstriction GO:0042310 15 11 0,000 0,05341492 0,09931635 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,05341492 0,09923613 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,05341492 0,09915603 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,05341492 0,09907607 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,05341492 0,09899623 ! ribosome assembly GO:0042255 13 11 0,000 0,05341492 0,09891653 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,05341492 0,09883695 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,05341492 0,0987575 ! chromatin silencing GO:0006342 19 11 0,000 0,05341492 0,09867817 ! nucleosome positioning GO:0016584 13 11 0,000 0,05341492 0,09859898 ! T cell homeostasis GO:0043029 20 11 0,000 0,05341492 0,09851991 ! regulation of isotype switching GO:0045191 19 11 0,000 0,05341492 0,09844097 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,05341492 0,09836215 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,05341492 0,09828346 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,05341492 0,0982049 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,05341492 0,09812646 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,05341492 0,09804815 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,05341492 0,09796996 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,05341492 0,09789189 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,05341492 0,09781395 ! male genitalia development GO:0030539 13 11 0,000 0,05341492 0,09773614 ! cholesterol efflux GO:0033344 19 11 0,000 0,05341492 0,09765845 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,05341492 0,09758088 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,05341492 0,09750343 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,05341492 0,09742611 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,05341492 0,09734891 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,05341492 0,09727183 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,05341492 0,09719488 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,05341492 0,09711805 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,05341492 0,09704133 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,05341492 0,09696474 ! lysogeny GO:0030069 18 11 0,000 0,05341492 0,09688827 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,05341492 0,09681192 ! acrosome reaction GO:0007340 13 11 0,000 0,05341492 0,09673569 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,05341492 0,09665958 ! amine biosynthetic process GO:0009309 97 76 1,000 0,05505163 0,09954304 ! gland development GO:0048732 148 77 1,000 0,05634154 0,1017954 ! sex differentiation GO:0007548 105 77 1,000 0,05634154 0,1017155 ! protein ubiquitination GO:0016567 125 77 1,000 0,05634154 0,10163573 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,05764205 0,10390025 ! nitrogen compound catabolic process GO:0044270 114 78 1,000 0,05764205 0,10381888 ! lactation GO:0007595 20 12 0,000 0,05812862 0,10461332 ! reproductive cellular process GO:0048610 14 12 0,000 0,05812862 0,10453152 ! tRNA modification GO:0006400 14 12 0,000 0,05812862 0,10444986 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,05812862 0,10436832 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,05812862 0,10428691 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,05812862 0,10420563 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,05812862 0,10412447 ! non-recombinational repair GO:0000726 19 12 0,000 0,05812862 0,10404344 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,05812862 0,10396253 ! peroxisomal transport GO:0043574 21 12 0,000 0,05812862 0,10388175 ! cartilage condensation GO:0001502 18 12 0,000 0,05812862 0,1038011 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,05812862 0,10372057 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,05812862 0,10364017 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,05812862 0,10355989 ! heart looping GO:0001947 15 12 0,000 0,05812862 0,10347973 ! palate development GO:0060021 15 12 0,000 0,05812862 0,1033997 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,05812862 0,1033198 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,05812862 0,10324001 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,05812862 0,10316035 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,05812862 0,10308082 ! arginine metabolic process GO:0006525 13 12 0,000 0,05812862 0,1030014 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,05812862 0,10292211 ! methionine metabolic process GO:0006555 13 12 0,000 0,05812862 0,10284294 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,05812862 0,10276389 ! Golgi organization GO:0007030 18 12 0,000 0,05812862 0,10268496 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,05812862 0,10260615 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,05812862 0,10252747 ! monoamine transport GO:0015844 13 12 0,000 0,05812862 0,1024489 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05812862 0,10237046 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,05812862 0,10229213 ! L-amino acid transport GO:0015807 20 12 0,000 0,05812862 0,10221393 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,05812862 0,10213584 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,05812862 0,10205788 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,05812862 0,10198003 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05812862 0,1019023 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,05812862 0,10182469 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,05812862 0,1017472 ! cerebellum development GO:0021549 13 12 0,000 0,05812862 0,10166982 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,05812862 0,10159257 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,05812862 0,10151543 ! histone methylation GO:0016571 15 12 0,000 0,05812862 0,1014384 ! autonomic nervous system development GO:0048483 23 12 0,000 0,05812862 0,1013615 ! gland morphogenesis GO:0022612 23 12 0,000 0,05812862 0,10128471 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,05812862 0,10120804 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,05812862 0,10113148 ! regulation of epidermis development GO:0045682 17 12 0,000 0,05812862 0,10105504 ! intestinal absorption GO:0050892 19 12 0,000 0,05812862 0,10097871 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,05812862 0,1009025 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,05812862 0,10082641 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,05812862 0,10075043 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,05812862 0,10067456 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,05812862 0,10059881 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,05812862 0,10052317 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,05812862 0,10044765 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,05812862 0,10037224 ! response to cold GO:0009409 14 12 0,000 0,05812862 0,10029694 ! mRNA transport GO:0051028 121 81 1,000 0,06160577 0,10621684 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,06160577 0,10613728 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,0628191 0,10814666 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,0628191 0,10806577 ! cGMP metabolic process GO:0046068 16 13 0,000 0,0628191 0,10798501 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,0628191 0,10790436 ! water transport GO:0006833 17 13 0,000 0,0628191 0,10782383 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,0628191 0,10774343 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,0628191 0,10766314 ! lipid localization GO:0010876 24 13 0,000 0,0628191 0,10758298 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,0628191 0,10750293 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,0628191 0,107423 ! organelle fusion GO:0048284 28 13 0,000 0,0628191 0,10734319 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,0628191 0,1072635 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,0628191 0,10718393 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,0628191 0,10710448 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,0628191 0,10702514 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,0628191 0,10694592 ! response to hexose stimulus GO:0009746 19 13 0,000 0,0628191 0,10686682 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,0628191 0,10678783 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,0628191 0,10670896 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,0628191 0,10663021 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,0628191 0,10655158 ! NAD metabolic process GO:0019674 21 13 0,000 0,0628191 0,10647306 ! exocrine system development GO:0035272 27 13 0,000 0,0628191 0,10639465 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,0628191 0,10631636 ! bone mineralization GO:0030282 15 13 0,000 0,0628191 0,10623819 ! regulation of exocytosis GO:0017157 17 13 0,000 0,0628191 0,10616013 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,0628191 0,10608219 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,0628191 0,10600436 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,0628191 0,10592664 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,0628191 0,10584904 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,0628191 0,10577155 ! genitalia development GO:0048806 15 13 0,000 0,0628191 0,10569418 ! cellular pigmentation GO:0033059 24 13 0,000 0,0628191 0,10561691 ! tissue regeneration GO:0042246 21 13 0,000 0,0628191 0,10553976 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,0628191 0,10546273 ! cofactor transport GO:0051181 19 13 0,000 0,0628191 0,1053858 ! NADP metabolic process GO:0006739 18 13 0,000 0,0628191 0,10530899 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,0628191 0,10523229 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,0628191 0,1051557 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0628191 0,10507923 ! gas transport GO:0015669 18 13 0,000 0,0628191 0,10500286 ! regulation of RNA stability GO:0043487 28 13 0,000 0,0628191 0,10492661 ! heme biosynthetic process GO:0006783 20 13 0,000 0,0628191 0,10485046 ! regulation of axon extension GO:0030516 23 13 0,000 0,0628191 0,10477443 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,0628191 0,10469851 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,0628191 0,10462269 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,0628191 0,10454699 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,0628191 0,10447139 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,0628191 0,10439591 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,0628191 0,10432053 ! ossification GO:0001503 134 82 1,000 0,0629473 0,104458 GO:0060348|bone development, ! regulation of cell adhesion GO:0030155 159 83 1,000 0,06429876 0,10662375 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,0674865 0,11182921 ! superoxide anion generation GO:0042554 18 14 0,000 0,0674865 0,1117487 ! neuron maturation GO:0042551 21 14 0,000 0,0674865 0,11166831 ! regulation of S phase GO:0033261 18 14 0,000 0,0674865 0,11158803 ! myotube differentiation GO:0014902 21 14 0,000 0,0674865 0,11150786 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,0674865 0,11142782 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,0674865 0,11134788 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,0674865 0,11126806 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,0674865 0,11118836 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,0674865 0,11110877 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,0674865 0,11102929 ! gene silencing by RNA GO:0031047 20 14 0,000 0,0674865 0,11094993 ! response to cAMP GO:0051591 19 14 0,000 0,0674865 0,11087068 ! limbic system development GO:0021761 25 14 0,000 0,0674865 0,11079154 ! startle response GO:0001964 21 14 0,000 0,0674865 0,11071252 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,0674865 0,11063361 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,0674865 0,11055481 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,0674865 0,11047612 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,0674865 0,11039754 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,0674865 0,11031908 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,0674865 0,11024073 ! glycine metabolic process GO:0006544 22 14 0,000 0,0674865 0,11016249 ! pituitary gland development GO:0021983 23 14 0,000 0,0674865 0,11008436 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,0674865 0,11000634 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,0674865 0,10992843 ! regulation of heart rate GO:0002027 23 14 0,000 0,0674865 0,10985064 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,0674865 0,10977295 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,0674865 0,10969537 ! embryo implantation GO:0007566 27 14 0,000 0,0674865 0,1096179 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,0674865 0,10954054 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,0674865 0,10946329 ! axon cargo transport GO:0008088 27 14 0,000 0,0674865 0,10938615 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,0674865 0,10930912 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,0674865 0,10923219 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,0674865 0,10915538 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,0674865 0,10907867 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0674865 0,10900207 ! mRNA splice site selection GO:0006376 26 14 0,000 0,0674865 0,10892558 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,0674865 0,10884919 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,0674865 0,10877291 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,0674865 0,10869674 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,0674865 0,10862068 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,0674865 0,10854472 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,0674865 0,10846887 ! muscle maintenance GO:0046716 19 14 0,000 0,0674865 0,10839312 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,0674865 0,10831748 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,0674865 0,10824194 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,0674865 0,10816651 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,0674865 0,10809119 ! cell killing GO:0001906 20 14 0,000 0,0674865 0,10801597 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,0674865 0,10794085 ! cilium assembly GO:0042384 20 14 0,000 0,0674865 0,10786584 ! peptide hormone secretion GO:0030072 23 14 0,000 0,0674865 0,10779094 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,0698013 0,11141082 GO:0060538|skeletal muscle organ development, ! carboxylic acid catabolic process GO:0046395 122 88 1,000 0,07120048 0,11356526 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 1,000 0,07120048 0,11348656 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! positive regulation of cell size GO:0045793 20 15 0,000 0,07213092 0,11488996 ! metencephalon development GO:0022037 19 15 0,000 0,07213092 0,11481045 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,07213092 0,11473106 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,07213092 0,11465177 ! skin development GO:0043588 25 15 0,000 0,07213092 0,11457259 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,07213092 0,11449352 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,07213092 0,11441456 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,07213092 0,1143357 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,07213092 0,11425696 ! bile acid metabolic process GO:0008206 22 15 0,000 0,07213092 0,11417833 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,07213092 0,1140998 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,07213092 0,11402138 ! adult walking behavior GO:0007628 25 15 0,000 0,07213092 0,11394307 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,07213092 0,11386486 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,07213092 0,11378677 ! myoblast differentiation GO:0045445 27 15 0,000 0,07213092 0,11370878 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,07213092 0,1136309 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,07213092 0,11355312 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,07213092 0,11347545 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,07213092 0,11339789 ! cerebral cortex development GO:0021987 29 15 0,000 0,07213092 0,11332043 ! response to osmotic stress GO:0006970 22 15 0,000 0,07213092 0,11324308 ! vesicle coating GO:0006901 25 15 0,000 0,07213092 0,11316583 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,07213092 0,11308869 ! DNA integration GO:0015074 22 15 0,000 0,07213092 0,11301165 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,07213092 0,11293472 ! peptide secretion GO:0002790 27 15 0,000 0,07213092 0,1128579 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,07213092 0,11278117 ! regulation of vasodilation GO:0042312 24 15 0,000 0,07213092 0,11270456 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,07213092 0,11262804 ! neuron recognition GO:0008038 22 15 0,000 0,07213092 0,11255163 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,07213092 0,11247533 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,07213092 0,11239912 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,07213092 0,11232302 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,07213092 0,11224703 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,07213092 0,11217113 ! biomineral formation GO:0031214 18 15 0,000 0,07213092 0,11209534 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,07213092 0,11201965 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,07213092 0,11194407 ! dopamine metabolic process GO:0042417 30 15 0,000 0,07213092 0,11186858 ! organic cation transport GO:0015695 19 15 0,000 0,07213092 0,1117932 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,07213092 0,11171792 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,07213092 0,11164274 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,07213092 0,11156766 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 27 15 0,000 0,07213092 0,11149268 ! peptide hormone processing GO:0016486 19 15 0,000 0,07213092 0,1114178 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,07213092 0,11134302 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,07260882 0,11200556 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,07402621 0,11411547 ! RNA localization GO:0006403 135 91 1,000 0,07545252 0,1162363 ! protein secretion GO:0009306 27 16 0,000 0,07675247 0,11815975 ! hormone secretion GO:0046879 25 16 0,000 0,07675247 0,11808072 ! bone remodeling GO:0046849 24 16 0,000 0,07675247 0,11800179 ! endothelial cell migration GO:0043542 22 16 0,000 0,07675247 0,11792296 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,07675247 0,11784424 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07675247 0,11776562 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,07675247 0,11768711 ! glial cell development GO:0021782 24 16 0,000 0,07675247 0,11760871 ! patterning of blood vessels GO:0001569 24 16 0,000 0,07675247 0,11753041 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,07675247 0,11745221 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,07675247 0,11737412 ! protein polyubiquitination GO:0000209 26 16 0,000 0,07675247 0,11729613 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,07675247 0,11721824 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,07675247 0,11714046 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,07675247 0,11706278 ! fructose metabolic process GO:0006000 20 16 0,000 0,07675247 0,1169852 ! regulation of protein binding GO:0043393 27 16 0,000 0,07675247 0,11690773 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,07675247 0,11683036 ! protein export from nucleus GO:0006611 24 16 0,000 0,07675247 0,11675309 ! negative regulation of immune response GO:0050777 28 16 0,000 0,07675247 0,11667592 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,07675247 0,11659886 ! DNA replication initiation GO:0006270 25 16 0,000 0,07675247 0,1165219 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,07675247 0,11644503 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,07675247 0,11636827 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,07675247 0,11629161 ! diencephalon development GO:0021536 25 16 0,000 0,07675247 0,11621506 ! oogenesis GO:0048477 23 16 0,000 0,07675247 0,1161386 ! neural crest cell migration GO:0001755 24 16 0,000 0,07675247 0,11606224 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,07675247 0,11598599 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,07675247 0,11590983 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,07675247 0,11583377 ! steroid catabolic process GO:0006706 22 16 0,000 0,07675247 0,11575782 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,07675247 0,11568196 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,07675247 0,1156062 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,07675247 0,11553054 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,07675247 0,11545498 ! sperm-egg recognition GO:0035036 16 16 0,000 0,07675247 0,11537952 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,07675247 0,11530416 ! nerve development GO:0021675 18 16 0,000 0,07675247 0,1152289 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,07675247 0,11515373 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,07675247 0,11507866 ! DNA recombination GO:0006310 146 92 1,000 0,07688762 0,11520621 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,07688762 0,11513121 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,07833141 0,11721681 ! angiogenesis GO:0001525 149 95 1,000 0,08124454 0,12149704 ! carboxylic acid transport GO:0046942 147 95 1,000 0,08124454 0,12141809 GO:0015849|organic acid transport, ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,08135126 0,12149863 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,08135126 0,12141979 ! negative regulation of defense response GO:0031348 19 17 0,000 0,08135126 0,12134105 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,08135126 0,12126241 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,08135126 0,12118387 ! glycerol metabolic process GO:0006071 20 17 0,000 0,08135126 0,12110544 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,08135126 0,1210271 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,08135126 0,12094887 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,08135126 0,12087073 ! signal complex assembly GO:0007172 29 17 0,000 0,08135126 0,1207927 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,08135126 0,12071477 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,08135126 0,12063694 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,08135126 0,12055921 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,08135126 0,12048158 ! memory GO:0007613 25 17 0,000 0,08135126 0,12040405 ! keratinization GO:0031424 17 17 0,000 0,08135126 0,12032662 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,08135126 0,12024929 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,08135126 0,12017206 ! retinoid metabolic process GO:0001523 22 17 0,000 0,08135126 0,12009493 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,08135126 0,12001789 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,08135126 0,11994096 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,08135126 0,11986412 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,08135126 0,11978739 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,08135126 0,11971075 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,08135126 0,11963421 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,08135126 0,11955776 ! membrane budding GO:0006900 29 17 0,000 0,08135126 0,11948142 ! heme metabolic process GO:0042168 27 17 0,000 0,08135126 0,11940517 ! neuromuscular junction development GO:0007528 23 17 0,000 0,08135126 0,11932902 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,08135126 0,11925296 ! body fluid secretion GO:0007589 27 17 0,000 0,08135126 0,119177 ! stem cell differentiation GO:0048863 36 17 0,000 0,08135126 0,11910114 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,08135126 0,11902538 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,08135126 0,11894971 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,08135126 0,11887414 ! sensory perception of pain GO:0019233 23 17 0,000 0,08135126 0,11879867 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,08135126 0,11872329 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,08135126 0,118648 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,08135126 0,11857281 ! synaptogenesis GO:0007416 24 17 0,000 0,08135126 0,11849772 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,08135126 0,11842272 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,08135126 0,11834782 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,08135126 0,11827301 ! cell-cell junction organization GO:0045216 25 17 0,000 0,08135126 0,11819829 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,08135126 0,11812367 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,08135126 0,11804915 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,08135126 0,11797471 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,08135126 0,11790038 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,08135126 0,11782613 ! in utero embryonic development GO:0001701 147 96 1,000 0,08271365 0,11972397 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,08271365 0,11964867 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,08271365 0,11957347 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,08592741 0,12414136 ! positive regulation of translation GO:0045727 28 18 0,000 0,08592741 0,12406343 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,08592741 0,1239856 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,08592741 0,12390786 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,08592741 0,12383023 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,08592741 0,12375269 ! cAMP metabolic process GO:0046058 33 18 0,000 0,08592741 0,12367524 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,08592741 0,1235979 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,08592741 0,12352065 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,08592741 0,1234435 ! axis specification GO:0009798 26 18 0,000 0,08592741 0,12336644 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,08592741 0,12328948 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,08592741 0,12321262 ! pancreas development GO:0031016 26 18 0,000 0,08592741 0,12313585 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,08592741 0,12305918 ! glutamine metabolic process GO:0006541 23 18 0,000 0,08592741 0,1229826 ! response to retinoic acid GO:0032526 25 18 0,000 0,08592741 0,12290612 ! pigmentation during development GO:0048066 31 18 0,000 0,08592741 0,12282973 ! central nervous system neuron development GO:0021954 30 18 0,000 0,08592741 0,12275344 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,08592741 0,12267724 ! fucose metabolic process GO:0006004 26 18 0,000 0,08592741 0,12260114 ! response to fungus GO:0009620 19 18 0,000 0,08592741 0,12252513 ! peptide cross-linking GO:0018149 31 18 0,000 0,08592741 0,12244922 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,08592741 0,1223734 ! heart process GO:0003015 27 18 0,000 0,08592741 0,12229767 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,08592741 0,12222204 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,08592741 0,1221465 ! visual learning GO:0008542 35 18 0,000 0,08592741 0,12207106 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,08592741 0,1219957 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,08592741 0,12192044 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,08592741 0,12184528 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,08592741 0,1217702 ! vitamin transport GO:0051180 24 18 0,000 0,08592741 0,12169522 ! hormone transport GO:0009914 27 18 0,000 0,08592741 0,12162033 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,08592741 0,12154554 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,08592741 0,12147083 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,08592741 0,12139622 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,08592741 0,12132169 ! cell-cell recognition GO:0009988 20 18 0,000 0,08592741 0,12124726 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,08592741 0,12117292 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,08592741 0,12109868 ! regulation of glucose import GO:0046324 21 18 0,000 0,08592741 0,12102452 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,08592741 0,12095045 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,08592741 0,12087648 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,08592741 0,12080259 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,08716975 0,1224743 ! regulation of translation GO:0006417 151 100 1,000 0,08867099 0,1245075 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,09048102 0,12697154 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,09048102 0,12689412 ! positive regulation of ossification GO:0045778 30 19 0,000 0,09048102 0,12681679 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,09048102 0,12673956 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,09048102 0,12666242 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,09048102 0,12658537 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,09048102 0,12650842 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,09048102 0,12643156 ! regeneration GO:0031099 32 19 0,000 0,09048102 0,1263548 ! response to alkaloid GO:0043279 32 19 0,000 0,09048102 0,12627813 ! sensory perception of taste GO:0050909 23 19 0,000 0,09048102 0,12620155 ! smooth muscle contraction GO:0006939 36 19 0,000 0,09048102 0,12612506 ! peroxisome organization GO:0007031 29 19 0,000 0,09048102 0,12604867 ! digestive system process GO:0022600 30 19 0,000 0,09048102 0,12597237 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,09048102 0,12589616 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,09048102 0,12582004 ! response to vitamin A GO:0033189 26 19 0,000 0,09048102 0,12574402 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,09048102 0,12566809 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,09048102 0,12559225 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,09048102 0,1255165 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,09048102 0,12544084 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,09048102 0,12536527 ! plasma membrane fusion GO:0045026 23 19 0,000 0,09048102 0,1252898 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,09048102 0,12521441 ! cytolysis GO:0019835 20 19 0,000 0,09048102 0,12513912 ! renal system process GO:0003014 35 19 0,000 0,09048102 0,12506391 ! vasodilation GO:0042311 33 19 0,000 0,09048102 0,1249888 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,09048102 0,12491378 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,09048102 0,12483884 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,09048102 0,124764 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,09048102 0,12468925 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,09048102 0,12461458 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,09048102 0,12454001 ! sarcomere organization GO:0045214 23 19 0,000 0,09048102 0,12446552 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,09048102 0,12439113 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,09048102 0,12431682 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,09048102 0,1242426 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,09048102 0,12416847 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,09048102 0,12409443 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,09048102 0,12402047 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,09048102 0,12394661 ! protein stabilization GO:0050821 26 19 0,000 0,09048102 0,12387283 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,09501221 0,12999886 ! iron ion transport GO:0006826 37 20 0,000 0,09501221 0,12992157 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,09501221 0,12984438 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,09501221 0,12976727 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,09501221 0,12969026 ! response to vitamin GO:0033273 29 20 0,000 0,09501221 0,12961334 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,09501221 0,12953651 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,09501221 0,12945977 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,09501221 0,12938312 ! spinal cord development GO:0021510 31 20 0,000 0,09501221 0,12930656 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,09501221 0,12923009 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,09501221 0,12915372 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,09501221 0,12907743 ! chromosome condensation GO:0030261 31 20 0,000 0,09501221 0,12900123 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,09501221 0,12892512 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,09501221 0,12884911 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,09501221 0,12877318 ! pallium development GO:0021543 38 20 0,000 0,09501221 0,12869734 ! DNA modification GO:0006304 28 20 0,000 0,09501221 0,12862159 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,09501221 0,12854593 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,09501221 0,12847036 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,09501221 0,12839488 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,09501221 0,12831949 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,09501221 0,12824418 ! collagen catabolic process GO:0030574 25 20 0,000 0,09501221 0,12816897 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,09501221 0,12809384 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,09501221 0,1280188 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,09501221 0,12794384 ! alditol metabolic process GO:0019400 24 20 0,000 0,09501221 0,12786898 ! actin filament-based movement GO:0030048 34 20 0,000 0,09501221 0,1277942 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,09952108 0,13378053 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,09952108 0,13370239 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,09952108 0,13362434 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,09952108 0,13354638 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,09952108 0,13346851 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,09952108 0,13339073 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,09952108 0,13331304 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,09952108 0,13323544 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,09952108 0,13315794 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,09952108 0,13308052 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,09952108 0,13300319 ! vesicle docking GO:0048278 27 21 0,000 0,09952108 0,13292595 ! phototransduction GO:0007602 25 21 0,000 0,09952108 0,13284881 ! dendrite development GO:0016358 35 21 0,000 0,09952108 0,13277175 ! visual behavior GO:0007632 39 21 0,000 0,09952108 0,13269478 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,09952108 0,1326179 ! ovarian follicle development GO:0001541 30 21 0,000 0,09952108 0,13254111 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,09952108 0,13246441 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,09952108 0,13238779 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,09952108 0,13231127 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,09952108 0,13223483 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,09952108 0,13215848 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,09952108 0,13208222 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,09952108 0,13200605 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,09952108 0,13192997 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,09952108 0,13185397 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,09952108 0,13177806 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,09952108 0,13170224 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,09952108 0,13162651 ! immunoglobulin production GO:0002377 33 21 0,000 0,09952108 0,13155086 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,09952108 0,1314753 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,09952108 0,13139982 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,09952108 0,13132444 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,09952108 0,13124914 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,09952108 0,13117392 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,09952108 0,13109879 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,09952108 0,13102375 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,09952108 0,1309488 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,09952108 0,13087392 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,09952108 0,13079914 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,09952108 0,13072444 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,09952108 0,13064983 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,09952108 0,1305753 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,10400775 0,13638416 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,10400775 0,13630645 ! viral genome replication GO:0019079 29 22 0,000 0,10400775 0,13622883 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,10400775 0,13615129 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,10400775 0,13607385 ! leukocyte adhesion GO:0007159 38 22 0,000 0,10400775 0,13599649 ! molting cycle process GO:0022404 40 22 0,000 0,10400775 0,13591922 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! glutamate signaling pathway GO:0007215 34 22 0,000 0,10400775 0,13584204 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,10400775 0,13576494 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,10400775 0,13568793 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,10400775 0,13561101 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,10400775 0,13553418 ! lysosome organization GO:0007040 37 22 0,000 0,10400775 0,13545743 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,10400775 0,13538077 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,10400775 0,1353042 ! regulation of behavior GO:0050795 38 22 0,000 0,10400775 0,13522771 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,10400775 0,13515131 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,10400775 0,135075 ! membrane depolarization GO:0051899 35 22 0,000 0,10400775 0,13499877 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,10400775 0,13492263 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,10400775 0,13484658 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,10400775 0,13477061 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,10400775 0,13469472 ! blastocyst development GO:0001824 37 22 0,000 0,10400775 0,13461892 ! neural tube closure GO:0001843 33 22 0,000 0,10400775 0,13454321 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,10400775 0,13446758 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,10847232 0,14016086 ! neuron fate commitment GO:0048663 32 23 0,000 0,10847232 0,14008216 ! embryonic pattern specification GO:0009880 31 23 0,000 0,10847232 0,14000355 ! myelination GO:0042552 35 23 0,000 0,10847232 0,13992503 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,10847232 0,1398466 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,10847232 0,13976825 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,10847232 0,13968999 ! vesicle targeting GO:0006903 32 23 0,000 0,10847232 0,13961182 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,10847232 0,13953374 ! osteoblast differentiation GO:0001649 40 23 0,000 0,10847232 0,13945574 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,10847232 0,13937784 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,10847232 0,13930002 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,10847232 0,13922228 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,10847232 0,13914463 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,10847232 0,13906707 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,10847232 0,1389896 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,10847232 0,13891221 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,10847232 0,13883491 ! pentose metabolic process GO:0019321 31 23 0,000 0,10847232 0,13875769 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,10847232 0,13868056 ! spermatid development GO:0007286 33 23 0,000 0,10847232 0,13860352 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,10847232 0,13852656 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,10847232 0,13844968 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,10847232 0,13837289 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,10847232 0,13829619 ! telomere organization GO:0032200 32 23 0,000 0,10847232 0,13821957 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,10847232 0,13814304 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,10847232 0,13806659 ! regulation of amine transport GO:0051952 38 23 0,000 0,10847232 0,13799023 ! liver development GO:0001889 40 23 0,000 0,10847232 0,13791395 ! initiation of viral infection GO:0019059 42 24 0,000 0,11291489 0,14348301 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,11291489 0,14340378 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,11291489 0,14332464 ! superoxide metabolic process GO:0006801 32 24 0,000 0,11291489 0,14324559 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,11291489 0,14316662 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,11291489 0,14308774 ! fat cell differentiation GO:0045444 37 24 0,000 0,11291489 0,14300895 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,11291489 0,14293024 ! sperm motility GO:0030317 27 24 0,000 0,11291489 0,14285162 ! vacuole organization GO:0007033 39 24 0,000 0,11291489 0,14277309 ! receptor metabolic process GO:0043112 37 24 0,000 0,11291489 0,14269464 ! neural crest cell development GO:0014032 39 24 0,000 0,11291489 0,14261628 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,11291489 0,14253801 ! primary neural tube formation GO:0014020 35 24 0,000 0,11291489 0,14245982 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,11291489 0,14238172 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,11291489 0,1423037 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,11291489 0,14222577 ! glutathione metabolic process GO:0006749 29 24 0,000 0,11291489 0,14214792 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,11291489 0,14207016 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,11291489 0,14199248 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,11733558 0,14747095 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,11733558 0,14739041 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,11733558 0,14730995 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,11733558 0,14722959 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,11733558 0,14714931 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,11733558 0,14706912 ! peptide transport GO:0015833 43 25 0,000 0,11733558 0,14698902 ! iron ion homeostasis GO:0055072 39 25 0,000 0,11733558 0,146909 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,11733558 0,14682907 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,11733558 0,14674923 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,11733558 0,14666948 ! phospholipid transport GO:0015914 35 25 0,000 0,11733558 0,14658981 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,11733558 0,14651023 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,11733558 0,14643073 ! detection of light stimulus GO:0009583 30 25 0,000 0,11733558 0,14635132 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,11733558 0,146272 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,11733558 0,14619276 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,11733558 0,14611361 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,12173449 0,15150938 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,12173449 0,15142744 ! translational initiation GO:0006413 43 26 0,000 0,12173449 0,15134559 ! circadian rhythm GO:0007623 42 26 0,000 0,12173449 0,15126382 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,12173449 0,15118215 ! post-embryonic development GO:0009791 42 26 0,000 0,12173449 0,15110056 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,12173449 0,15101906 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,12173449 0,15093765 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,12173449 0,15085632 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,12173449 0,15077508 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,12173449 0,15069394 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,12173449 0,15061287 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,12173449 0,1505319 ! regulation of coagulation GO:0050818 39 26 0,000 0,12173449 0,15045101 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,12611173 0,15577711 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,12611173 0,1556935 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,12611173 0,15560997 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,12611173 0,15552653 ! membrane docking GO:0022406 39 27 0,000 0,12611173 0,15544319 ! catechol metabolic process GO:0009712 43 27 0,000 0,12611173 0,15535993 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,12611173 0,15527676 ! acute-phase response GO:0006953 42 27 0,000 0,12611173 0,15519368 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,12611173 0,15511069 ! myofibril assembly GO:0030239 36 27 0,000 0,12611173 0,15502778 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,12611173 0,15494497 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,12611173 0,15486224 ! natural killer cell activation GO:0030101 35 27 0,000 0,12611173 0,15477961 ! lipid oxidation GO:0034440 38 27 0,000 0,12611173 0,15469706 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,12611173 0,1546146 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,12611173 0,15453222 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,12611173 0,15444994 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,12611173 0,15436774 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,12611173 0,15428563 ! gene silencing GO:0016458 41 27 0,000 0,12611173 0,15420361 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,13046741 0,15944476 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,13046741 0,15936008 ! phenol metabolic process GO:0018958 44 28 0,000 0,13046741 0,1592755 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,13046741 0,159191 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,13046741 0,15910659 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,13046741 0,15902228 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,13046741 0,15893805 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,13046741 0,15885391 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,13046741 0,15876986 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,13046741 0,1586859 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,13046741 0,15860203 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,13046741 0,15851824 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,13046741 0,15843455 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,13046741 0,15835094 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,13046741 0,15826742 ! mesoderm formation GO:0001707 46 28 0,000 0,13046741 0,15818399 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,13046741 0,15810065 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,13046741 0,15801739 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,13046741 0,15793423 ! ensheathment of neurons GO:0007272 43 28 0,000 0,13046741 0,15785115 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,13046741 0,15776816 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,13046741 0,15768525 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,13046741 0,15760243 ! neural tube formation GO:0001841 41 28 0,000 0,13046741 0,1575197 ! placenta development GO:0001890 37 28 0,000 0,13046741 0,15743706 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,13480162 0,16258192 ! regulation of innate immune response GO:0045088 38 29 0,000 0,13480162 0,16249671 ! ovulation cycle process GO:0022602 41 29 0,000 0,13480162 0,16241159 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,13480162 0,16232656 ! protein targeting to membrane GO:0006612 53 29 0,000 0,13480162 0,16224161 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,13480162 0,16215676 ! mismatch repair GO:0006298 34 29 0,000 0,13480162 0,16207199 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,13480162 0,16198731 ! muscle cell development GO:0055001 38 29 0,000 0,13480162 0,16190273 ! formation of primary germ layer GO:0001704 48 29 0,000 0,13480162 0,16181823 ! telencephalon development GO:0021537 52 29 0,000 0,13480162 0,16173381 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,13480162 0,16164949 ! eye morphogenesis GO:0048592 51 29 0,000 0,13480162 0,16156525 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,13480162 0,1614811 ! tissue homeostasis GO:0001894 42 29 0,000 0,13480162 0,16139704 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,13911447 0,16647413 ! collagen metabolic process GO:0032963 40 30 0,000 0,13911447 0,16638756 ! organic anion transport GO:0015711 51 30 0,000 0,13911447 0,16630108 ! cholesterol transport GO:0030301 46 30 0,000 0,13911447 0,16621469 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,13911447 0,16612839 ! spliceosome assembly GO:0000245 49 30 0,000 0,13911447 0,16604218 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,13911447 0,16595606 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,13911447 0,16587003 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,13911447 0,16578409 ! ceramide metabolic process GO:0006672 43 30 0,000 0,13911447 0,16569823 ! ovulation cycle GO:0042698 43 30 0,000 0,13911447 0,16561247 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,13911447 0,16552679 ! adult locomotory behavior GO:0008344 47 30 0,000 0,13911447 0,1654412 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,13911447 0,1653557 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,13911447 0,16527029 ! response to heat GO:0009408 41 30 0,000 0,13911447 0,16518497 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,13911447 0,16509974 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,13911447 0,16501459 ! negative regulation of secretion GO:0051048 49 31 0,000 0,14340607 0,17001751 ! mammary gland development GO:0030879 57 31 0,000 0,14340607 0,16992992 ! glial cell differentiation GO:0010001 55 31 0,000 0,14340607 0,16984242 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,14340607 0,169755 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,14340607 0,16966768 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,14340607 0,16958045 ! odontogenesis GO:0042476 50 31 0,000 0,14340607 0,16949331 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,14340607 0,16940625 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,14340607 0,16931929 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,14340607 0,16923241 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,14340607 0,16914563 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,14340607 0,16905893 ! cell fate specification GO:0001708 37 31 0,000 0,14340607 0,16897232 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,14340607 0,1688858 ! RNA modification GO:0009451 40 31 0,000 0,14340607 0,16879937 ! regulation of muscle development GO:0048634 48 32 0,000 0,14767653 0,17373709 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,14767653 0,17364827 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,14767653 0,17355954 ! meiosis I GO:0007127 52 32 0,000 0,14767653 0,1734709 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,14767653 0,17338234 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,14767653 0,17329388 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,14767653 0,17320551 GO:0006639|acylglycerol metabolic process, ! peripheral nervous system development GO:0007422 53 32 0,000 0,14767653 0,17311723 ! regulation of protein stability GO:0031647 48 32 0,000 0,14767653 0,17302904 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,14767653 0,17294094 ! cytokine production GO:0001816 44 32 0,000 0,14767653 0,17285293 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,14767653 0,17276501 ! vesicle localization GO:0051648 47 32 0,000 0,14767653 0,17267718 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,15192593 0,17755572 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,15192593 0,17746554 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,15192593 0,17737546 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,15192593 0,17728546 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,15192593 0,17719556 ! sister chromatid segregation GO:0000819 46 33 0,000 0,15192593 0,17710575 ! actomyosin structure organization GO:0031032 43 33 0,000 0,15192593 0,17701603 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,15192593 0,1769264 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,15192593 0,17683687 ! nucleus organization GO:0006997 49 33 0,000 0,15192593 0,17674742 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,15192593 0,17665806 ! female gonad development GO:0008585 49 33 0,000 0,15192593 0,1765688 ! positive regulation of cell development GO:0010720 54 33 0,000 0,15192593 0,17647962 ! lipid homeostasis GO:0055088 55 33 0,000 0,15192593 0,17639053 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,15192593 0,17630154 ! regulation of proteolysis GO:0030162 50 33 0,000 0,15192593 0,17621263 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,15192593 0,17612381 ! cytokinesis GO:0000910 52 33 0,000 0,15192593 0,17603509 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,15192593 0,17594645 ! mRNA catabolic process GO:0006402 48 34 0,000 0,1561544 0,18075245 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,1561544 0,18066153 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,1561544 0,18057069 ! feeding behavior GO:0007631 45 34 0,000 0,1561544 0,18047996 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,1561544 0,18038931 ! neuron migration GO:0001764 46 34 0,000 0,1561544 0,18029875 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,1561544 0,18020829 ! female gamete generation GO:0007292 43 34 0,000 0,1561544 0,18011791 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,1561544 0,18002763 ! aerobic respiration GO:0009060 47 34 0,000 0,1561544 0,17993743 ! embryonic organ development GO:0048568 45 34 0,000 0,1561544 0,17984733 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,1561544 0,17975731 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,16036202 0,18450857 ! Notch signaling pathway GO:0007219 56 35 0,000 0,16036202 0,18441632 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,16036202 0,18432416 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,16036202 0,18423209 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,16036202 0,18414011 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,16036202 0,18404822 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,16036202 0,18395643 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,16036202 0,18386473 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,16036202 0,18377311 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,16036202 0,18368159 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,16036202 0,18359016 ! glycogen metabolic process GO:0005977 48 35 0,000 0,16036202 0,18349883 ! pigment metabolic process GO:0042440 61 35 0,000 0,16036202 0,18340758 ! protein homooligomerization GO:0051260 52 35 0,000 0,16036202 0,18331642 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,1645489 0,18800917 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,1645489 0,18791582 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,1645489 0,18782256 ! organic ether metabolic process GO:0018904 46 36 0,000 0,1645489 0,1877294 ! tissue remodeling GO:0048771 62 36 0,000 0,1645489 0,18763632 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,1645489 0,18754334 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,1645489 0,18745045 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,1645489 0,18735766 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,1645489 0,18726495 ! glucan metabolic process GO:0044042 49 36 0,000 0,1645489 0,18717234 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,16871514 0,19181652 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,16871514 0,19172175 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,16871514 0,19162707 ! learning GO:0007612 67 37 0,000 0,16871514 0,19153249 ! ion transmembrane transport GO:0034220 56 37 0,000 0,16871514 0,191438 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,16871514 0,1913436 ! regulation of protein secretion GO:0050708 51 37 0,000 0,16871514 0,1912493 ! amino acid activation GO:0043038 52 37 0,000 0,16871514 0,19115508 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,16871514 0,19106097 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,17286084 0,19565942 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,17286084 0,19556318 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,17286084 0,19546703 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,17286084 0,19537098 ! phagocytosis GO:0006909 60 38 0,000 0,17286084 0,19527502 ! mesenchymal cell development GO:0014031 64 38 0,000 0,17286084 0,19517915 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 0,000 0,17286084 0,19508338 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,17698611 0,19964102 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,17698611 0,19954316 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,17698611 0,19944539 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,17698611 0,19934772 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,17698611 0,19925014 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,17698611 0,19915266 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,17698611 0,19905528 ! chromatin remodeling GO:0006338 68 39 0,000 0,17698611 0,19895799 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,17698611 0,19886079 ! JNK cascade GO:0007254 54 39 0,000 0,17698611 0,19876369 ! developmental growth GO:0048589 62 39 0,000 0,17698611 0,19866669 ! cell growth GO:0016049 61 39 0,000 0,17698611 0,19856978 ! synapse organization GO:0050808 55 39 0,000 0,17698611 0,19847296 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,18109103 0,20297728 ! response to calcium ion GO:0051592 58 40 0,000 0,18109103 0,20287841 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,18109103 0,20277964 ! regulation of tube size GO:0035150 60 40 0,000 0,18109103 0,20268096 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,18109103 0,20258238 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,18109103 0,20248389 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,18109103 0,20238551 ! peptide metabolic process GO:0006518 56 40 0,000 0,18109103 0,20228721 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,18109103 0,20218902 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,18109103 0,20209091 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,18109103 0,20199291 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,18109103 0,20189499 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,18517572 0,20634891 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,18517572 0,20624898 ! endosome transport GO:0016197 71 41 0,000 0,18517572 0,20614915 ! striated muscle contraction GO:0006941 62 41 0,000 0,18517572 0,20604942 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,18517572 0,20594978 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,18517572 0,20585024 ! biopolymer methylation GO:0043414 62 41 0,000 0,18517572 0,2057508 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,18517572 0,20565145 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,18924026 0,210064 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,18924026 0,20996266 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,18924026 0,20986143 ! cellular component disassembly GO:0022411 64 42 0,000 0,18924026 0,20976029 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,18924026 0,20965925 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,18924026 0,2095583 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,18924026 0,20945746 ! excretion GO:0007588 63 42 0,000 0,18924026 0,20935671 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,18924026 0,20925606 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,18924026 0,2091555 ! regulation of cell shape GO:0008360 78 42 0,000 0,18924026 0,20905504 ! neuromuscular process GO:0050905 79 43 0,000 0,19328476 0,21342052 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,19328476 0,21331811 ! tRNA processing GO:0008033 49 43 0,000 0,19328476 0,2132158 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,19328476 0,21311359 ! vesicle organization GO:0016050 79 43 0,000 0,19328476 0,21301148 ! methylation GO:0032259 64 43 0,000 0,19328476 0,21290946 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,19730932 0,2172386 ! glycolysis GO:0006096 53 44 0,000 0,19730932 0,21713466 ! regulation of action potential GO:0001508 71 44 0,000 0,19730932 0,21703081 ! regulation of ion transport GO:0043269 57 44 0,000 0,19730932 0,21692707 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,19730932 0,21682343 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,19730932 0,21671988 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,19730932 0,21661643 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,19730932 0,21651309 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,19730932 0,21640984 ! RNA catabolic process GO:0006401 64 45 0,000 0,20131402 0,22069698 ! positive regulation of defense response GO:0031349 59 45 0,000 0,20131402 0,22059183 ! regulation of translational initiation GO:0006446 64 45 0,000 0,20131402 0,22048679 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,20131402 0,22038185 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,20131402 0,220277 ! cell recognition GO:0008037 58 45 0,000 0,20131402 0,22017226 ! cell maturation GO:0048469 60 45 0,000 0,20131402 0,22006761 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,20529898 0,22431718 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,20529898 0,22421066 ! cell redox homeostasis GO:0045454 63 46 0,000 0,20529898 0,22410425 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,20529898 0,22399794 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,20529898 0,22389173 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,20926428 0,22810798 ! viral infectious cycle GO:0019058 71 47 0,000 0,20926428 0,22799993 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,20926428 0,22789197 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,20926428 0,22778412 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,20926428 0,22767637 ! chloride transport GO:0006821 67 48 0,000 0,21321002 0,2318596 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,21321002 0,23175003 ! response to temperature stimulus GO:0009266 62 48 0,000 0,21321002 0,23164055 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,21321002 0,23153119 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,21321002 0,23142192 ! gastrulation GO:0007369 73 48 0,000 0,21321002 0,23131276 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,21321002 0,2312037 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,21321002 0,23109475 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,21321002 0,23098589 ! regulation of endocytosis GO:0030100 63 48 0,000 0,21321002 0,23087714 ! nuclear export GO:0051168 69 48 0,000 0,21321002 0,2307685 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,21321002 0,23065995 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,21321002 0,23055151 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,2171363 0,23468679 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,2171363 0,23457656 ! sensory perception of smell GO:0007608 61 49 0,000 0,2171363 0,23446643 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,2171363 0,2343564 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,2171363 0,23424648 ! RNA elongation GO:0006354 62 49 0,000 0,2171363 0,23413666 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,2171363 0,23402694 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,2171363 0,23391733 ! cartilage development GO:0051216 70 49 0,000 0,2171363 0,23380782 ! maintenance of location GO:0051235 84 49 0,000 0,2171363 0,23369841 ! regulation of actin filament length GO:0030832 72 50 0,000 0,22104321 0,23779204 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,22104321 0,23768087 ! membrane fusion GO:0006944 80 50 0,000 0,22104321 0,23756981 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,22104321 0,23745884 ! proton transport GO:0015992 75 50 0,000 0,22104321 0,23734798 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,22104321 0,23723723 ! positive regulation of secretion GO:0051047 71 51 0,000 0,22493084 0,24129708 ! hydrogen transport GO:0006818 77 51 0,000 0,22493084 0,24118459 ! muscle fiber development GO:0048747 74 51 0,000 0,22493084 0,2410722 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,22493084 0,24095992 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,22493084 0,24084774 ! adult behavior GO:0030534 80 51 0,000 0,22493084 0,24073566 ! transition metal ion transport GO:0000041 74 52 0,000 0,2287993 0,24476204 ! regulation of cellular component size GO:0032535 74 52 0,000 0,2287993 0,24464825 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,2287993 0,24453457 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,23264866 0,24853318 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,23264866 0,24841779 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,23264866 0,24830252 ! single fertilization GO:0007338 59 53 0,000 0,23264866 0,24818735 ! amino acid transport GO:0006865 84 54 0,000 0,23647904 0,2521566 ! glucose catabolic process GO:0006007 66 54 0,000 0,23647904 0,25203975 ! DNA catabolic process GO:0006308 67 54 0,000 0,23647904 0,25192301 ! detection of external stimulus GO:0009581 66 54 0,000 0,23647904 0,25180638 ! exocytosis GO:0006887 74 55 0,000 0,24029051 0,25574649 ! mesoderm development GO:0007498 76 55 0,000 0,24029051 0,2556282 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,24029051 0,25551002 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,24029051 0,25539195 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,24408317 0,25930314 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,24785712 0,26319084 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,24785712 0,26306939 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,24785712 0,26294805 ! secondary metabolic process GO:0019748 84 57 0,000 0,24785712 0,26282682 ! developmental maturation GO:0021700 75 57 0,000 0,24785712 0,2627057 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,25161244 0,26656315 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,25161244 0,26644042 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,25534922 0,27027299 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,25534922 0,27014867 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,25906756 0,2739565 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,25906756 0,2738306 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,25906756 0,27370482 ! regulation of heart contraction GO:0008016 91 60 0,000 0,25906756 0,27357915 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,25906756 0,27345359 ! fertilization GO:0009566 68 60 0,000 0,25906756 0,27332816 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,26276754 0,2771047 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,26276754 0,2769777 ! extracellular matrix organization GO:0030198 103 61 0,000 0,26276754 0,27685082 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,26276754 0,27672406 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! neurotransmitter transport GO:0006836 81 62 0,000 0,26644926 0,28047291 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,26644926 0,2803446 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,26644926 0,28021641 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,2701128 0,28393942 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,27375826 0,28764002 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,27375826 0,28750867 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,27375826 0,28737745 ! hexose catabolic process GO:0019320 82 64 0,000 0,27375826 0,28724635 ! adaptive immune response GO:0002250 94 64 0,000 0,27375826 0,28711536 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! defense response to bacterium GO:0042742 73 65 0,000 0,27738571 0,29078721 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,27738571 0,29065474 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,27738571 0,29052238 ! activation of immune response GO:0002253 83 65 0,000 0,27738571 0,29039014 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,28099526 0,29403508 ! antigen processing and presentation GO:0019882 96 66 0,000 0,28099526 0,29390136 ! axon guidance GO:0007411 99 66 0,000 0,28099526 0,29376777 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,28099526 0,2936343 ! regulation of immune effector process GO:0002697 101 66 0,000 0,28099526 0,29350095 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,28458698 0,29711759 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,28458698 0,29698278 ! acute inflammatory response GO:0002526 92 68 0,000 0,28816096 0,30057606 ! learning or memory GO:0007611 123 68 0,000 0,28816096 0,30043981 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,28816096 0,30030368 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,28816096 0,30016767 ! rhythmic process GO:0048511 105 68 0,000 0,28816096 0,30003179 ! inorganic anion transport GO:0015698 93 68 0,000 0,28816096 0,29989603 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,2917173 0,30345988 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,2917173 0,30332269 ! response to metal ion GO:0010038 103 70 0,000 0,29525607 0,30686351 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,29525607 0,30672491 ! humoral immune response GO:0006959 86 70 0,000 0,29525607 0,30658644 ! amine transport GO:0015837 101 70 0,000 0,29525607 0,30644808 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,29525607 0,30630986 ! muscle cell differentiation GO:0042692 104 71 0,000 0,29877736 0,30982323 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,29877736 0,30968361 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,29877736 0,30954411 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,29877736 0,30940474 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,30228126 0,31289239 ! negative regulation of transport GO:0051051 116 73 0,000 0,30576785 0,316359 ! regulation of blood pressure GO:0008217 107 73 0,000 0,30576785 0,31621675 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,30576785 0,31607463 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,30923721 0,31951734 ! digestion GO:0007586 97 74 0,000 0,30923721 0,31937386 ! blood coagulation GO:0007596 116 75 0,000 0,31268944 0,32279431 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,31268944 0,32264949 ! response to nutrient GO:0007584 104 75 0,000 0,31268944 0,3225048 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,31268944 0,32236025 ! tRNA metabolic process GO:0006399 95 76 0,000 0,31612461 0,32575565 ! response to unfolded protein GO:0006986 99 76 0,000 0,31612461 0,32560976 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,31612461 0,32546401 ! regulation of protein transport GO:0051223 114 76 0,000 0,31612461 0,32531839 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,31954281 0,32868894 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,31954281 0,328542 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,31954281 0,3283952 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,31954281 0,32824853 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,31954281 0,32810199 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,32294412 0,33144644 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,32632862 0,33477066 ! cellular respiration GO:0045333 107 79 0,000 0,32632862 0,33462141 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,32632862 0,33447229 ! regulation of lyase activity GO:0051339 133 79 0,000 0,32632862 0,33432331 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,32632862 0,33417445 ! chromatin assembly GO:0031497 102 80 0,000 0,3296964 0,33747295 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,3296964 0,33732282 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,3296964 0,33717284 ! forebrain development GO:0030900 131 80 0,000 0,3296964 0,33702298 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,33304753 0,34029734 ! hemostasis GO:0007599 125 81 0,000 0,33304753 0,34014623 ! response to protein stimulus GO:0051789 111 81 0,000 0,33304753 0,33999526 ! regulation of neurological system process GO:0031644 122 81 0,000 0,33304753 0,33984442 ! vitamin metabolic process GO:0006766 103 81 0,000 0,33304753 0,33969371 ! detection of stimulus GO:0051606 108 82 0,000 0,3363821 0,34294274 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,33970019 0,3461721 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,33970019 0,34601879 ! regulation of defense response GO:0031347 117 84 0,000 0,34300188 0,34922723 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,34300188 0,34907271 ! sterol metabolic process GO:0016125 120 84 0,000 0,34300188 0,34891832 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,34628725 0,35210463 ! rRNA metabolic process GO:0016072 107 85 0,000 0,34628725 0,35194903 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,34628725 0,35179358 ! regulation of protein localization GO:0032880 132 85 0,000 0,34628725 0,35163826 ! regulation of membrane potential GO:0042391 128 85 0,000 0,34628725 0,35148308 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,34628725 0,35132804 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,34955637 0,35448839 ! nucleosome organization GO:0034728 114 87 0,000 0,35280934 0,35762956 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,35280934 0,35747202 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,35280934 0,35731461 ! female pregnancy GO:0007565 130 87 0,000 0,35280934 0,35715734 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,35604622 0,36027554 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,35604622 0,36011711 ! protein processing GO:0016485 114 88 0,000 0,35604622 0,35995882 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,3592671 0,36305551 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,3592671 0,36289606 ! regulation of T cell activation GO:0050863 128 89 0,000 0,3592671 0,36273676 ! hormone metabolic process GO:0042445 121 90 0,000 0,36247206 0,36581208 ! ATP metabolic process GO:0046034 137 91 0,000 0,36566116 0,36886872 ! response to virus GO:0009615 122 91 0,000 0,36566116 0,368707 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,3688345 0,3717438 ! positive regulation of immune response GO:0050778 121 92 0,000 0,3688345 0,37158097 ! sulfur metabolic process GO:0006790 118 92 0,000 0,3688345 0,37141828 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,37199214 0,3744341 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,37199214 0,37427031 ! electron transport chain GO:0022900 123 94 0,000 0,37513417 0,37726654 ! response to oxidative stress GO:0006979 141 94 0,000 0,37513417 0,37710165 ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,38137167 0,38320439 ! protein maturation GO:0051604 129 96 0,000 0,38137167 0,38303705 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,3844673 0,38597765 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,3844673 0,38580925 ! calcium ion transport GO:0006816 167 99 0,000 0,3906127 0,39180515 ! extracellular structure organization GO:0043062 156 99 0,000 0,3906127 0,39163436 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,39366262 0,39452027 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,39366262 0,39434844 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,39366262 0,39417676 ! divalent metal ion transport GO:0070838 171 100 0,000 0,39366262 0,39400523 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,39366262 0,39383385 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,39366262 0,39366262