pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1102-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of epithelial cell proliferation GO:0050678 122 45 6,000 8,647E-11 2,112E-07 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 4,000 2,768E-08 3,382E-05 ! ribosomal large subunit biogenesis GO:0042273 13 13 3,000 5,856E-08 4,769E-05 ! epithelial to mesenchymal transition GO:0001837 30 15 3,000 1,113E-07 6,796E-05 ! regulation of keratinocyte differentiation GO:0045616 6 5 2,000 2,793E-07 1,365E-04 ! cell growth GO:0016049 90 46 4,000 3,066E-07 1,248E-04 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 3,000 3,13E-07 1,092E-04 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 3,000 8,48E-07 2,589E-04 ! positive regulation of protein ubiquitination GO:0031398 14 7 2,000 9,731E-07 2,641E-04 ! regulation of epidermal cell differentiation GO:0045604 8 7 2,000 9,731E-07 2,377E-04 ! positive regulation of epidermis development GO:0045684 13 8 2,000 1,553E-06 3,45E-04 ! UTP metabolic process GO:0046051 10 9 2,000 2,325E-06 4,733E-04 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! CTP metabolic process GO:0046036 11 10 2,000 3,314E-06 6,228E-04 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 10 2,000 3,314E-06 5,783E-04 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 4,547E-06 7,405E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 2,000 4,547E-06 6,942E-04 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 2,000 4,547E-06 6,534E-04 ! drug transport GO:0015893 16 12 2,000 6,048E-06 8,209E-04 ! mesenchymal cell development GO:0014031 94 41 3,000 7,763E-06 9,982E-04 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 2,000 7,845E-06 9,583E-04 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 7,845E-06 9,127E-04 ! regulation of erythrocyte differentiation GO:0045646 47 13 2,000 7,845E-06 8,712E-04 ! regulation of epidermis development GO:0045682 19 13 2,000 7,845E-06 8,333E-04 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 2,000 1,243E-05 1,265E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 1,467E-05 1,434E-03 ! regulation of protein ubiquitination GO:0031396 28 16 2,000 1,526E-05 1,434E-03 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 2,000 1,526E-05 1,381E-03 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 2,000 2,214E-05 1,931E-03 ! detection of bacterium GO:0016045 22 18 2,000 2,214E-05 1,865E-03 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 2,000 4,14E-05 3,372E-03 ! inner ear receptor cell differentiation GO:0060113 42 22 2,000 4,14E-05 3,263E-03 ! mechanoreceptor differentiation GO:0042490 48 24 2,000 5,417E-05 4,136E-03 ! detection of biotic stimulus GO:0009595 34 24 2,000 5,417E-05 4,01E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 5,417E-05 3,893E-03 ! pyrimidine nucleoside metabolic process GO:0006213 34 24 2,000 5,417E-05 3,781E-03 ! lung development GO:0030324 165 69 3,000 6,204E-05 4,21E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 6,204E-05 4,096E-03 ! respiratory tube development GO:0030323 171 72 3,000 7,331E-05 4,713E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 7,777E-05 4,871E-03 ! respiratory system development GO:0060541 175 74 3,000 8,161E-05 4,984E-03 ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 9,262E-05 5,519E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 9,262E-05 5,387E-03 ! microvillus organization GO:0032528 8 5 1,000 9,262E-05 5,262E-03 GO:0030033|microvillus assembly, ! mRNA transcription GO:0009299 10 5 1,000 9,262E-05 5,143E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 9,262E-05 5,028E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 9,262E-05 4,919E-03 ! regulation of sensory perception GO:0051931 8 5 1,000 9,262E-05 4,814E-03 GO:0051930|regulation of sensory perception of pain, ! protein insertion into membrane GO:0051205 17 5 1,000 9,262E-05 4,714E-03 ! cellular iron ion homeostasis GO:0006879 57 29 2,000 9,672E-05 4,822E-03 ! steroid biosynthetic process GO:0006694 146 79 3,000 1,053E-04 5,146E-03 ! positive regulation of phosphorylation GO:0042327 149 81 3,000 1,161E-04 5,56E-03 ! iron ion homeostasis GO:0055072 60 31 2,000 1,184E-04 5,565E-03 ! response to drug GO:0042493 149 83 3,000 1,276E-04 5,882E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 1,276E-04 5,773E-03 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 1,387E-04 6,159E-03 ! embryonic hemopoiesis GO:0035162 16 6 1,000 1,387E-04 6,049E-03 ! transepithelial chloride transport GO:0030321 12 6 1,000 1,387E-04 5,943E-03 GO:0070633|transepithelial transport, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 1,387E-04 5,84E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 1,387E-04 5,741E-03 ! 5S class rRNA transcription GO:0042791 13 6 1,000 1,387E-04 5,646E-03 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! oxygen homeostasis GO:0032364 10 6 1,000 1,387E-04 5,553E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 1,387E-04 5,463E-03 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 2,000 1,861E-04 7,215E-03 ! tRNA transcription GO:0009304 17 7 1,000 1,937E-04 7,395E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,937E-04 7,281E-03 ! establishment of tissue polarity GO:0007164 8 7 1,000 1,937E-04 7,171E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 1,937E-04 7,064E-03 ! peptidyl-threonine modification GO:0018210 26 7 1,000 1,937E-04 6,96E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 1,937E-04 6,859E-03 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 2,02E-04 7,051E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,578E-04 8,87E-03 ! hemoglobin metabolic process GO:0020027 14 8 1,000 2,578E-04 8,747E-03 ! gas homeostasis GO:0033483 14 8 1,000 2,578E-04 8,627E-03 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 1,000 2,578E-04 8,51E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 2,578E-04 8,397E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 2,578E-04 8,286E-03 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 2,578E-04 8,179E-03 ! ribonucleoside metabolic process GO:0009119 64 42 2,000 2,952E-04 9,245E-03 ! epithelial cell differentiation GO:0030855 83 43 2,000 3,166E-04 9,791E-03 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 3,166E-04 9,668E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,308E-04 9,976E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 3,308E-04 9,855E-03 ! glycine catabolic process GO:0006546 15 9 1,000 3,308E-04 9,736E-03 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 4,126E-04 0,01200085 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 1,000 4,126E-04 0,01185967 ! induction of an organ GO:0001759 17 10 1,000 4,126E-04 0,01172176 ! serine family amino acid catabolic process GO:0009071 18 10 1,000 4,126E-04 0,01158703 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 4,126E-04 0,01145536 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 4,126E-04 0,01132665 ! positive regulation of DNA binding GO:0043388 83 48 2,000 4,388E-04 0,01191126 ! JAK-STAT cascade GO:0007259 82 48 2,000 4,388E-04 0,01178037 ! epidermal cell differentiation GO:0009913 87 50 2,000 4,951E-04 0,01314586 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 5,033E-04 0,01322171 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 5,033E-04 0,01308106 ! telomere maintenance via telomerase GO:0007004 24 11 1,000 5,033E-04 0,01294336 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 5,033E-04 0,01280853 ! regulation of embryonic development GO:0045995 35 11 1,000 5,033E-04 0,01267649 ! positive regulation of binding GO:0051099 88 52 2,000 5,557E-04 0,01385332 ! inner ear development GO:0048839 89 53 2,000 5,878E-04 0,01450388 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 2,000 5,878E-04 0,01435884 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 6,028E-04 0,01458008 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 6,028E-04 0,01443714 ! histone acetylation GO:0016573 27 12 1,000 6,028E-04 0,01429697 ! regulation of hormone metabolic process GO:0032350 28 12 1,000 6,028E-04 0,0141595 ! peptidyl-lysine modification GO:0018205 21 12 1,000 6,028E-04 0,01402465 ! developmental induction GO:0031128 22 12 1,000 6,028E-04 0,01389234 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 1,000 6,028E-04 0,0137625 ! localization within membrane GO:0051668 26 12 1,000 6,028E-04 0,01363507 ! regulation of protein polymerization GO:0032271 117 55 2,000 6,553E-04 0,01468735 ! cGMP metabolic process GO:0046068 18 13 1,000 7,109E-04 0,01578951 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 18 13 1,000 7,109E-04 0,01564726 ! pseudouridine synthesis GO:0001522 19 13 1,000 7,109E-04 0,01550756 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 7,109E-04 0,01537032 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 7,276E-04 0,01559289 ! positive regulation of cell migration GO:0030335 137 58 2,000 7,656E-04 0,01626422 ! rRNA transcription GO:0009303 28 14 1,000 8,278E-04 0,01743331 ! RNA-dependent DNA replication GO:0006278 28 14 1,000 8,278E-04 0,01728431 ! positive regulation of protein polymerization GO:0032273 27 14 1,000 8,278E-04 0,01713783 ! cytokine-mediated signaling pathway GO:0019221 112 61 2,000 8,871E-04 0,01821083 ! nucleoside metabolic process GO:0009116 91 62 2,000 9,301E-04 0,0189352 ! regulation of homeostatic process GO:0032844 148 62 2,000 9,301E-04 0,01877871 ! lactation GO:0007595 30 15 1,000 9,532E-04 0,0190878 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 9,532E-04 0,01893261 ! phospholipid catabolic process GO:0009395 27 15 1,000 9,532E-04 0,01877993 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 9,532E-04 0,01862969 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 9,532E-04 0,01848184 ! muscle maintenance GO:0046716 26 15 1,000 9,532E-04 0,01833631 ! regulation of protein complex assembly GO:0043254 132 63 2,000 9,744E-04 0,01859797 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 1,02E-03 0,01931839 ! positive regulation of cell motion GO:0051272 157 65 2,000 1,067E-03 0,02005276 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,087E-03 0,02027526 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 1,000 1,087E-03 0,02012166 ! startle response GO:0001964 28 16 1,000 1,087E-03 0,01997037 ! stem cell development GO:0048864 46 16 1,000 1,087E-03 0,01982134 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 1,087E-03 0,01967451 ! ear development GO:0043583 114 66 2,000 1,115E-03 0,02003628 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 1,115E-03 0,01989003 ! detection of external stimulus GO:0009581 102 68 2,000 1,216E-03 0,02152972 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 1,23E-03 0,0216128 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 1,23E-03 0,02145842 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 1,000 1,23E-03 0,02130623 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 1,378E-03 0,0237036 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 1,381E-03 0,023587 ! heart looping GO:0001947 34 18 1,000 1,381E-03 0,0234232 ! glycine metabolic process GO:0006544 30 18 1,000 1,381E-03 0,02326166 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 1,381E-03 0,02310234 ! neural crest cell migration GO:0001755 41 18 1,000 1,381E-03 0,02294518 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 1,381E-03 0,02279014 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 1,54E-03 0,0252498 ! regulation of caspase activity GO:0043281 136 74 2,000 1,552E-03 0,02528143 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 1,552E-03 0,025114 ! positive regulation of angiogenesis GO:0045766 50 20 1,000 1,708E-03 0,02744663 ! protein amino acid acetylation GO:0006473 41 20 1,000 1,708E-03 0,02726724 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 1,708E-03 0,02709018 ! transcription from RNA polymerase III promoter GO:0006383 46 20 1,000 1,708E-03 0,0269154 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 1,708E-03 0,02674287 GO:0010675|regulation of cellular carbohydrate metabolic process, ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 1,708E-03 0,02657253 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 1,74E-03 0,02690445 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 1,884E-03 0,02894225 ! response to hypoxia GO:0001666 178 81 2,000 2,012E-03 0,03071467 ! stem cell differentiation GO:0048863 57 22 1,000 2,068E-03 0,03137817 ! vasodilation GO:0042311 40 22 1,000 2,068E-03 0,03118447 ! G1 phase GO:0051318 44 22 1,000 2,068E-03 0,03099316 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 2,068E-03 0,03080418 ! peptidyl-serine modification GO:0018209 50 22 1,000 2,068E-03 0,03061748 ! regulation of peptidase activity GO:0052547 150 82 2,000 2,083E-03 0,03066068 ! response to oxygen levels GO:0070482 183 83 2,000 2,157E-03 0,03154998 ! viral genome replication GO:0019079 44 23 1,000 2,26E-03 0,03286883 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 2,26E-03 0,03267434 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cell adhesion GO:0045785 61 24 1,000 2,461E-03 0,03536428 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 2,461E-03 0,03515748 ! protein amino acid O-linked glycosylation GO:0006493 45 24 1,000 2,461E-03 0,03495307 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 2,461E-03 0,03475103 ! barbed-end actin filament capping GO:0051016 58 24 1,000 2,461E-03 0,03455131 GO:0051693|actin filament capping, ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 2,461E-03 0,03435388 ! regulation of DNA binding GO:0051101 167 89 2,000 2,63E-03 0,03651284 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 2,67E-03 0,03684552 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 2,67E-03 0,03663852 ! positive regulation of protein modification process GO:0031401 156 90 2,000 2,715E-03 0,03705671 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 2,886E-03 0,03917235 ! neural crest cell development GO:0014032 59 26 1,000 2,886E-03 0,03895593 GO:0014033|neural crest cell differentiation, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 2,886E-03 0,03874189 ! telomere organization GO:0032200 46 26 1,000 2,886E-03 0,03853018 GO:0000723|telomere maintenance, ! regulation of cell adhesion GO:0030155 241 92 2,000 2,89E-03 0,03836506 ! negative regulation of actin filament depolymerization GO:0030835 63 27 1,000 3,111E-03 0,04108058 ! negative regulation of actin filament polymerization GO:0030837 61 27 1,000 3,111E-03 0,04085971 ! iron ion transport GO:0006826 65 27 1,000 3,111E-03 0,04064121 ! cellular response to oxidative stress GO:0034599 43 27 1,000 3,111E-03 0,04042504 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 3,344E-03 0,0432179 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 3,344E-03 0,04299044 ! protein amino acid acylation GO:0043543 59 28 1,000 3,344E-03 0,04276536 ! sperm motility GO:0030317 37 28 1,000 3,344E-03 0,04254262 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 1,000 3,344E-03 0,0423222 ! negative regulation of protein polymerization GO:0032272 63 28 1,000 3,344E-03 0,04210404 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 3,454E-03 0,04326644 ! forebrain development GO:0030900 210 98 2,000 3,454E-03 0,04304569 ! somitogenesis GO:0001756 52 29 1,000 3,584E-03 0,04444534 ! regulation of actin filament depolymerization GO:0030834 67 30 1,000 3,832E-03 0,04728501 ! negative regulation of protein complex assembly GO:0031333 68 30 1,000 3,832E-03 0,0470474 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 3,832E-03 0,04681216 ! cell fate determination GO:0001709 64 30 1,000 3,832E-03 0,04657926 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 4,088E-03 0,04944634 ! collagen metabolic process GO:0032963 49 32 1,000 4,352E-03 0,05237832 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 4,352E-03 0,05212156 ! mesoderm formation GO:0001707 73 32 1,000 4,352E-03 0,05186731 ! positive regulation of catabolic process GO:0009896 72 32 1,000 4,352E-03 0,05161553 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 4,624E-03 0,05457115 ! leukocyte chemotaxis GO:0030595 55 33 1,000 4,624E-03 0,05430879 GO:0060326|cell chemotaxis, ! post-embryonic development GO:0009791 76 34 1,000 4,903E-03 0,05731257 ! formation of primary germ layer GO:0001704 76 34 1,000 4,903E-03 0,05703965 ! cell fate specification GO:0001708 56 34 1,000 4,903E-03 0,05676932 ! serine family amino acid metabolic process GO:0009069 56 34 1,000 4,903E-03 0,05650154 ! adult locomotory behavior GO:0008344 62 34 1,000 4,903E-03 0,05623627 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 5,19E-03 0,05924756 ! mesoderm morphogenesis GO:0048332 80 35 1,000 5,19E-03 0,05897199 ! calcium-mediated signaling GO:0019722 67 35 1,000 5,19E-03 0,05869897 ! placenta development GO:0001890 53 35 1,000 5,19E-03 0,05842847 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 5,484E-03 0,061459 ! embryonic organ development GO:0048568 67 36 1,000 5,484E-03 0,06117837 ! tissue remodeling GO:0048771 78 37 1,000 5,786E-03 0,06425211 ! regulation of microtubule-based process GO:0032886 86 37 1,000 5,786E-03 0,06396137 ! cyclic nucleotide metabolic process GO:0009187 69 38 1,000 6,095E-03 0,06707687 ! carbohydrate homeostasis GO:0033500 59 39 1,000 6,412E-03 0,07024551 GO:0042593|glucose homeostasis, ! mammary gland development GO:0030879 93 40 1,000 6,736E-03 0,07346607 ! gliogenesis GO:0042063 91 41 1,000 7,068E-03 0,07673734 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 7,068E-03 0,0763978 ! RNA modification GO:0009451 64 41 1,000 7,068E-03 0,07606124 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 7,406E-03 0,07935589 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 7,752E-03 0,08269871 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 76 43 1,000 7,752E-03 0,08233915 GO:0050880|regulation of blood vessel size, ! segmentation GO:0035282 78 43 1,000 7,752E-03 0,0819827 ! neuron migration GO:0001764 85 43 1,000 7,752E-03 0,08162933 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 8,105E-03 0,08498015 ! keratinocyte differentiation GO:0030216 81 45 1,000 8,465E-03 0,08837667 ! B cell differentiation GO:0030183 124 45 1,000 8,465E-03 0,0880006 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 8,832E-03 0,09142878 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 8,832E-03 0,091043 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 8,832E-03 0,09066047 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 8,832E-03 0,09028113 ! leukocyte migration GO:0050900 75 46 1,000 8,832E-03 0,08990496 ! positive regulation of protein transport GO:0051222 80 46 1,000 8,832E-03 0,08953191 ! vascular process in circulatory system GO:0003018 85 48 1,000 9,588E-03 0,09678797 ! protein homooligomerization GO:0051260 84 49 1,000 9,976E-03 0,10029183 ! induction of apoptosis by extracellular signals GO:0008624 99 50 1,000 0,01037085 0,10383597 ! activation of caspase activity GO:0006919 95 50 1,000 0,01037085 0,10341215 ! regulation of ossification GO:0030278 123 50 1,000 0,01037085 0,10299177 ! positive regulation of cytokine production GO:0001819 94 50 1,000 0,01037085 0,1025748 ! viral infectious cycle GO:0019058 104 51 1,000 0,01077272 0,10612002 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,0111814 0,1097035 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,0111814 0,10926468 ! histone modification GO:0016570 104 52 1,000 0,0111814 0,10882937 ! amino acid activation GO:0043038 98 52 1,000 0,0111814 0,1083975 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! chromatin remodeling GO:0006338 122 53 1,000 0,01159684 0,11198057 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,01159684 0,1115397 ! cartilage development GO:0051216 99 53 1,000 0,01159684 0,11110229 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,01201899 0,11469686 ! regulation of translational initiation GO:0006446 87 54 1,000 0,01201899 0,11425057 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,01201899 0,11380774 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 1,000 0,01201899 0,11336832 ! covalent chromatin modification GO:0016569 115 54 1,000 0,01201899 0,11293229 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,01244781 0,11651341 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 1,000 0,01244781 0,1160687 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,01244781 0,11562737 ! response to UV GO:0009411 120 55 1,000 0,01244781 0,11518939 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,01288325 0,118769 ! chloride transport GO:0006821 102 57 1,000 0,01332527 0,12238213 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,01332527 0,12192377 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,01332527 0,12146883 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,01332527 0,12101727 ! heart morphogenesis GO:0003007 105 57 1,000 0,01332527 0,12056906 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,01332527 0,12012416 ! regulation of actin filament length GO:0030832 118 58 1,000 0,01377383 0,12371131 ! gastrulation GO:0007369 122 58 1,000 0,01377383 0,12325816 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,01377383 0,12280831 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,01377383 0,12236173 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,01377383 0,1219184 ! adult behavior GO:0030534 104 60 1,000 0,01469039 0,12956181 ! regulation of cellular component size GO:0032535 125 61 1,000 0,0151583 0,13320764 ! camera-type eye development GO:0043010 126 61 1,000 0,0151583 0,1327302 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01524021 0,1329708 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01524021 0,1324976 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01524021 0,13202775 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01524021 0,13156122 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01524021 0,13109798 ! neuron fate determination GO:0048664 7 5 0,000 0,01524021 0,13063798 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01524021 0,13018121 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01524021 0,12972761 ! polyol transport GO:0015791 12 5 0,000 0,01524021 0,12927717 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01524021 0,12882985 ! response to superoxide GO:0000303 10 5 0,000 0,01524021 0,1283856 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01524021 0,12794442 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01524021 0,12750625 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01524021 0,12707108 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01524021 0,12663886 ! female meiosis GO:0007143 10 5 0,000 0,01524021 0,12620958 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01524021 0,12578319 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01524021 0,12535968 ! hypothalamus development GO:0021854 9 5 0,000 0,01524021 0,12493901 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01524021 0,12452115 ! cobalt ion transport GO:0006824 11 5 0,000 0,01524021 0,12410608 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01524021 0,12369377 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01524021 0,12328419 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01524021 0,12287731 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01524021 0,12247311 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01524021 0,12207156 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01524021 0,12167263 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01524021 0,1212763 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01524021 0,12088255 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01524021 0,12049134 ! transposition GO:0032196 9 5 0,000 0,01524021 0,12010266 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01524021 0,11971648 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01524021 0,11933277 ! negative chemotaxis GO:0050919 16 5 0,000 0,01524021 0,11895152 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01524021 0,11857269 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01524021 0,11819627 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01524021 0,11782223 ! behavioral response to pain GO:0048266 10 5 0,000 0,01524021 0,11745055 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01524021 0,11708121 ! Notch receptor processing GO:0007220 11 5 0,000 0,01524021 0,11671419 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01524021 0,11634945 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01524021 0,11598699 ! micturition GO:0060073 9 5 0,000 0,01524021 0,11562679 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01524021 0,11526881 ! copulation GO:0007620 9 5 0,000 0,01524021 0,11491304 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01524021 0,11455946 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01524021 0,11420805 ! bioluminescence GO:0008218 9 5 0,000 0,01524021 0,11385879 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01524021 0,11351166 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01524021 0,11316664 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01524021 0,11282371 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01524021 0,11248286 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01524021 0,11214405 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01524021 0,11180728 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01524021 0,11147253 ! grooming behavior GO:0007625 6 5 0,000 0,01524021 0,11113978 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01524021 0,110809 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01524021 0,11048019 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01524021 0,11015333 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01524021 0,10982839 ! response to protozoan GO:0001562 13 5 0,000 0,01524021 0,10950537 ! lymph vessel development GO:0001945 10 5 0,000 0,01524021 0,10918424 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01524021 0,10886499 ! endochondral ossification GO:0001958 17 5 0,000 0,01524021 0,1085476 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01524021 0,10823205 ! single strand break repair GO:0000012 8 5 0,000 0,01524021 0,10791833 ! parathyroid gland development GO:0060017 14 5 0,000 0,01524021 0,10760643 ! anagen GO:0042640 7 5 0,000 0,01524021 0,10729633 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01524021 0,106988 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01524021 0,10668145 ! cytokine secretion GO:0050663 15 5 0,000 0,01524021 0,10637664 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01524021 0,10607358 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01524021 0,10577223 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01524021 0,10547259 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01524021 0,10517465 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01524021 0,10487838 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01524021 0,10458378 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01524021 0,10429083 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01524021 0,10399951 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01524021 0,10370982 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01524021 0,10342174 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01524021 0,10313525 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01524021 0,10285035 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01524021 0,10256701 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01524021 0,10228523 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01524021 0,102005 ! valine metabolic process GO:0006573 12 5 0,000 0,01524021 0,1017263 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01524021 0,10144912 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01524021 0,10117344 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01524021 0,10089926 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01524021 0,10062655 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01524021 0,10035532 ! polyol catabolic process GO:0046174 9 5 0,000 0,01524021 0,10008555 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01524021 0,09981723 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01524021 0,09955033 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01524021 0,09928487 ! muscle cell migration GO:0014812 8 5 0,000 0,01524021 0,09902081 ! mitochondrial fission GO:0000266 8 5 0,000 0,01524021 0,09875816 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01524021 0,09849689 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01524021 0,09823701 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01524021 0,09797849 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01524021 0,09772133 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01524021 0,09746551 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01524021 0,09721103 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01524021 0,09695788 ! monocyte activation GO:0042117 10 5 0,000 0,01524021 0,09670604 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01524021 0,09645551 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01524021 0,09620627 ! response to food GO:0032094 6 5 0,000 0,01524021 0,09595831 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01524021 0,09571163 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01524021 0,09546622 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01524021 0,09522206 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01524021 0,09497915 ! forebrain neuron development GO:0021884 13 5 0,000 0,01524021 0,09473747 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01524021 0,09449702 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01524021 0,09425779 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01524021 0,09401976 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01524021 0,09378294 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01524021 0,0935473 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01524021 0,09331285 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01524021 0,09307956 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01524021 0,09284744 ! lipid glycosylation GO:0030259 7 5 0,000 0,01524021 0,09261648 ! nucleobase transport GO:0015851 6 5 0,000 0,01524021 0,09238666 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01524021 0,09215798 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01524021 0,09193043 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01524021 0,091704 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01524021 0,09147869 ! basic amino acid transport GO:0015802 12 5 0,000 0,01524021 0,09125447 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01524021 0,09103136 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01524021 0,09080933 ! actin nucleation GO:0045010 11 5 0,000 0,01524021 0,09058838 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01524021 0,09036851 ! depurination GO:0045007 5 5 0,000 0,01524021 0,0901497 ! depyrimidination GO:0045008 10 5 0,000 0,01524021 0,08993195 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01524021 0,08971524 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01524021 0,08949958 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01524021 0,08928495 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01524021 0,08907135 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01524021 0,08885877 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01524021 0,0886472 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01524021 0,08843664 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01524021 0,08822707 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01524021 0,0880185 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01524021 0,08781091 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01524021 0,08760429 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01524021 0,08739865 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01524021 0,08719397 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01524021 0,08699025 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01524021 0,08678747 ! response to arsenic GO:0046685 11 5 0,000 0,01524021 0,08658564 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01524021 0,08638475 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01524021 0,08618478 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01524021 0,08598574 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01524021 0,08578762 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01524021 0,0855904 ! response to mercury ion GO:0046689 8 5 0,000 0,01524021 0,08539409 ! response to cadmium ion GO:0046686 7 5 0,000 0,01524021 0,08519868 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01524021 0,08500417 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01524021 0,08481054 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01524021 0,08461778 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01524021 0,08442591 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01524021 0,0842349 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01524021 0,08404475 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01524021 0,08385546 ! decidualization GO:0046697 11 5 0,000 0,01524021 0,08366702 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01524021 0,08347943 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01524021 0,08329267 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01524021 0,08310675 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01524021 0,08292166 ! embryonic cleavage GO:0040016 6 5 0,000 0,01524021 0,08273739 ! peroxisome fission GO:0016559 5 5 0,000 0,01524021 0,08255394 ! histone demethylation GO:0016577 13 5 0,000 0,01524021 0,08237129 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01524021 0,08218946 ! mitotic recombination GO:0006312 9 5 0,000 0,01524021 0,08200843 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01524021 0,08182819 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01524021 0,08164874 ! metaphase plate congression GO:0051310 7 5 0,000 0,01524021 0,08147008 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01524021 0,08129219 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01524021 0,08111509 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01524021 0,08093875 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01524021 0,08076318 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01524021 0,08058837 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01524021 0,08041431 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01524021 0,080241 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01524021 0,08006844 ! B cell homeostasis GO:0001782 13 5 0,000 0,01524021 0,07989662 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01524021 0,07972554 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01524021 0,07955518 ! metaphase GO:0051323 11 5 0,000 0,01524021 0,07938555 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01524021 0,07921665 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01524021 0,07904846 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01524021 0,07888099 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01524021 0,07871422 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01524021 0,07854815 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01524021 0,07838279 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01524021 0,07821812 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01524021 0,07805414 ! response to redox state GO:0051775 6 5 0,000 0,01524021 0,07789085 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01524021 0,07772824 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01524021 0,0775663 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01524021 0,07740504 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01524021 0,07724445 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01524021 0,07708452 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01524021 0,07692526 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01524021 0,07676665 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01524021 0,07660869 ! striatum development GO:0021756 14 5 0,000 0,01524021 0,07645139 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01524021 0,07629472 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01524021 0,0761387 ! glial cell migration GO:0008347 10 5 0,000 0,01524021 0,07598332 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01524021 0,07582856 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01524021 0,07567444 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01524021 0,07552094 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01524021 0,07536807 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01524021 0,07521581 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01524021 0,07506416 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01524021 0,07491313 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01524021 0,0747627 ! neuroprotection GO:0043526 8 5 0,000 0,01524021 0,07461288 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01524021 0,07446365 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01524021 0,07431502 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01524021 0,07416698 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01524021 0,07401953 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01524021 0,07387267 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01524021 0,07372639 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01524021 0,07358068 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01524021 0,07343555 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01524021 0,07329099 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01524021 0,073147 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01524021 0,07300358 ! spindle assembly GO:0051225 6 5 0,000 0,01524021 0,07286071 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01524021 0,07271841 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01524021 0,07257666 ! protein palmitoylation GO:0018345 12 5 0,000 0,01524021 0,07243546 ! drug metabolic process GO:0017144 7 5 0,000 0,01524021 0,07229481 ! stem cell division GO:0017145 11 5 0,000 0,01524021 0,0721547 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01524021 0,07201514 ! organ regeneration GO:0031100 7 5 0,000 0,01524021 0,07187611 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01524021 0,07173762 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01524021 0,07159966 ! viral reproductive process GO:0022415 132 62 1,000 0,01563257 0,07330206 ! mesoderm development GO:0007498 128 63 1,000 0,01611317 0,07541086 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,01660004 0,07754092 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,01709315 0,07969192 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 1,000 0,01709315 0,07954013 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,01809791 0,08405551 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01826052 0,0846498 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01826052 0,08448948 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01826052 0,08432976 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01826052 0,08417065 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01826052 0,08401214 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01826052 0,08385422 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01826052 0,08369689 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01826052 0,08354016 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01826052 0,08338401 ! response to oxygen radical GO:0000305 11 6 0,000 0,01826052 0,08322844 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01826052 0,08307345 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01826052 0,08291904 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01826052 0,0827652 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01826052 0,08261193 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01826052 0,08245923 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01826052 0,08230709 ! forebrain regionalization GO:0021871 9 6 0,000 0,01826052 0,08215551 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01826052 0,08200449 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01826052 0,08185403 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01826052 0,08170411 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01826052 0,08155474 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01826052 0,08140592 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01826052 0,08125764 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01826052 0,0811099 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01826052 0,08096269 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01826052 0,08081602 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01826052 0,08066988 ! malate metabolic process GO:0006108 13 6 0,000 0,01826052 0,08052427 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01826052 0,08037918 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01826052 0,08023461 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01826052 0,08009056 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01826052 0,07994703 ! protein refolding GO:0042026 15 6 0,000 0,01826052 0,07980401 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01826052 0,07966151 ! opsonization GO:0008228 8 6 0,000 0,01826052 0,07951951 ! mating behavior GO:0007617 7 6 0,000 0,01826052 0,07937801 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01826052 0,07923702 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01826052 0,07909653 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01826052 0,07895654 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01826052 0,07881704 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01826052 0,07867803 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01826052 0,07853951 ! toxin metabolic process GO:0009404 11 6 0,000 0,01826052 0,07840148 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01826052 0,07826394 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01826052 0,07812687 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01826052 0,07799029 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01826052 0,07785418 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01826052 0,07771854 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01826052 0,07758338 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01826052 0,07744869 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01826052 0,07731446 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01826052 0,0771807 ! thymic T cell selection GO:0045061 16 6 0,000 0,01826052 0,0770474 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01826052 0,07691456 ! protein lipoylation GO:0009249 10 6 0,000 0,01826052 0,07678218 ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01826052 0,07665025 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01826052 0,07651877 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01826052 0,07638775 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01826052 0,07625717 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01826052 0,07612704 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01826052 0,07599735 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01826052 0,0758681 ! hyperosmotic response GO:0006972 10 6 0,000 0,01826052 0,07573929 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01826052 0,07561092 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01826052 0,07548298 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01826052 0,07535548 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01826052 0,0752284 ! urea metabolic process GO:0019627 7 6 0,000 0,01826052 0,07510176 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01826052 0,07497554 ! neutrophil activation GO:0042119 7 6 0,000 0,01826052 0,07484974 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01826052 0,07472436 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01826052 0,0745994 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01826052 0,07447486 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01826052 0,07435074 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01826052 0,07422703 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01826052 0,07410373 ! neuron apoptosis GO:0051402 15 6 0,000 0,01826052 0,07398084 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01826052 0,07385835 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01826052 0,07373627 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01826052 0,07361459 ! carnitine transport GO:0015879 10 6 0,000 0,01826052 0,07349332 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01826052 0,07337244 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01826052 0,07325196 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01826052 0,07313188 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01826052 0,07301218 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01826052 0,07289288 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01826052 0,07277397 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01826052 0,07265545 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01826052 0,07253731 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01826052 0,07241955 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01826052 0,07230218 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01826052 0,07218518 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01826052 0,07206857 ! response to UV-C GO:0010225 14 6 0,000 0,01826052 0,07195233 ! astrocyte development GO:0014002 16 6 0,000 0,01826052 0,07183646 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01826052 0,07172097 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01826052 0,07160585 ! interaction with symbiont GO:0051702 14 6 0,000 0,01826052 0,0714911 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01826052 0,07137671 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01826052 0,07126269 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01826052 0,07114903 ! response to copper ion GO:0046688 10 6 0,000 0,01826052 0,07103574 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01826052 0,0709228 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01826052 0,07081023 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01826052 0,07069801 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01826052 0,07058615 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01826052 0,07047464 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01826052 0,07036348 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01826052 0,07025267 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01826052 0,07014221 ! hair follicle maturation GO:0048820 8 6 0,000 0,01826052 0,07003209 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01826052 0,06992233 ! Schwann cell development GO:0014044 15 6 0,000 0,01826052 0,0698129 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01826052 0,06970382 ! response to pheromone GO:0019236 6 6 0,000 0,01826052 0,06959508 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01826052 0,06948667 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01826052 0,06937861 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01826052 0,06927088 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01826052 0,06916348 ! subpallium development GO:0021544 15 6 0,000 0,01826052 0,06905641 ! neural tube patterning GO:0021532 8 6 0,000 0,01826052 0,06894968 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01826052 0,06884328 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01826052 0,0687372 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01826052 0,06863145 ! G2 phase GO:0051319 16 6 0,000 0,01826052 0,06852603 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01826052 0,06842093 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01826052 0,06831615 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01826052 0,06821169 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01826052 0,06810755 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01826052 0,06800373 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01826052 0,06790022 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01826052 0,06779703 ! receptor internalization GO:0031623 11 6 0,000 0,01826052 0,06769415 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01826052 0,06759158 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01826052 0,06748933 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01826052 0,06738738 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01826052 0,06728574 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01826052 0,0671844 ! protein deubiquitination GO:0016579 16 6 0,000 0,01826052 0,06708337 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01826052 0,06698265 ! protein destabilization GO:0031648 9 6 0,000 0,01826052 0,06688222 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01826052 0,0667821 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01826052 0,06668228 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01826052 0,06658275 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01826052 0,06648352 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01826052 0,06638459 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01826052 0,06628595 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01826052 0,0661876 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01826052 0,06608955 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01826052 0,06599178 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01826052 0,0658943 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01826052 0,06579712 ! neural plate development GO:0001840 9 6 0,000 0,01826052 0,06570021 ! catecholamine transport GO:0051937 9 6 0,000 0,01826052 0,06560359 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01826052 0,06550726 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01826052 0,06541121 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01826052 0,06531544 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01826052 0,06521995 ! maternal placenta development GO:0001893 12 6 0,000 0,01826052 0,06512474 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01826052 0,0650298 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01826052 0,06493514 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01826052 0,06484076 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01826052 0,06474665 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01826052 0,06465282 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01826052 0,06455925 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01826052 0,06446596 GO:0055081|anion homeostasis, ! viral reproduction GO:0016032 142 68 1,000 0,01860948 0,06560312 ! regulation of lipase activity GO:0060191 137 68 1,000 0,01860948 0,06550859 ! cell projection assembly GO:0030031 138 68 1,000 0,01860948 0,06541433 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,01912712 0,06713728 ! B cell activation GO:0042113 179 72 1,000 0,02071603 0,07261014 ! humoral immune response GO:0006959 115 73 1,000 0,02125754 0,07440138 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02127165 0,07434426 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02127165 0,07423806 ! regulation of helicase activity GO:0051095 16 7 0,000 0,02127165 0,07413215 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02127165 0,07402655 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02127165 0,07392125 ! sleep GO:0030431 16 7 0,000 0,02127165 0,07381625 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02127165 0,07371154 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02127165 0,07360714 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02127165 0,07350303 ! prostate gland development GO:0030850 14 7 0,000 0,02127165 0,07339921 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02127165 0,07329568 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02127165 0,07319245 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02127165 0,07308951 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02127165 0,07298685 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02127165 0,07288449 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02127165 0,07278241 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02127165 0,07268061 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02127165 0,0725791 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02127165 0,07247788 ! glycolipid transport GO:0046836 11 7 0,000 0,02127165 0,07237693 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02127165 0,07227627 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02127165 0,07217589 ! neuron adhesion GO:0007158 14 7 0,000 0,02127165 0,07207578 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02127165 0,07197595 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02127165 0,0718764 ! mRNA stabilization GO:0048255 18 7 0,000 0,02127165 0,07177713 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02127165 0,07167812 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02127165 0,07157939 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02127165 0,07148093 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02127165 0,07138275 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02127165 0,07128483 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02127165 0,07118718 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02127165 0,07108979 ! lipoprotein transport GO:0042953 14 7 0,000 0,02127165 0,07099268 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02127165 0,07089582 ! rhythmic behavior GO:0007622 17 7 0,000 0,02127165 0,07079924 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02127165 0,07070291 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02127165 0,07060685 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02127165 0,07051104 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02127165 0,0704155 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02127165 0,07032022 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02127165 0,07022519 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02127165 0,07013042 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02127165 0,0700359 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02127165 0,06994164 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02127165 0,06984763 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02127165 0,06975388 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02127165 0,06966037 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02127165 0,06956712 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02127165 0,06947412 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02127165 0,06938136 ! spinal cord patterning GO:0021511 14 7 0,000 0,02127165 0,06928885 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02127165 0,06919659 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02127165 0,06910457 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02127165 0,0690128 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02127165 0,06892127 ! adrenal gland development GO:0030325 17 7 0,000 0,02127165 0,06882999 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02127165 0,06873894 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02127165 0,06864814 ! ovulation GO:0030728 10 7 0,000 0,02127165 0,06855757 ! adenohypophysis development GO:0021984 11 7 0,000 0,02127165 0,06846725 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02127165 0,06837716 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02127165 0,06828731 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02127165 0,06819769 ! microtubule nucleation GO:0007020 21 7 0,000 0,02127165 0,06810831 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02127165 0,06801916 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02127165 0,06793025 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02127165 0,06784157 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02127165 0,06775311 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02127165 0,06766489 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02127165 0,0675769 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02127165 0,06748914 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02127165 0,06740161 ! galactose metabolic process GO:0006012 13 7 0,000 0,02127165 0,0673143 ! vesicle fusion GO:0006906 20 7 0,000 0,02127165 0,06722722 ! response to dietary excess GO:0002021 8 7 0,000 0,02127165 0,06714036 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02127165 0,06705373 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02127165 0,06696732 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02127165 0,06688113 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02127165 0,06679517 ! organ growth GO:0035265 15 7 0,000 0,02127165 0,06670942 ! nucleoside transport GO:0015858 11 7 0,000 0,02127165 0,0666239 ! nucleoside salvage GO:0043174 11 7 0,000 0,02127165 0,06653859 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02127165 0,0664535 ! male sex determination GO:0030238 15 7 0,000 0,02127165 0,06636863 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02127165 0,06628398 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02127165 0,06619954 ! parturition GO:0007567 16 7 0,000 0,02127165 0,06611532 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02127165 0,06603131 ! rRNA modification GO:0000154 14 7 0,000 0,02127165 0,06594751 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02127165 0,06586393 ! spindle checkpoint GO:0031577 16 7 0,000 0,02127165 0,06578056 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02127165 0,06569739 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02127165 0,06561444 ! monocyte differentiation GO:0030224 16 7 0,000 0,02127165 0,0655317 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02127165 0,06544917 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02127165 0,06536684 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02127165 0,06528472 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02127165 0,06520281 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,02127165 0,0651211 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02127165 0,0650396 ! fibrinolysis GO:0042730 11 7 0,000 0,02127165 0,0649583 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02127165 0,0648772 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02127165 0,06479631 ! eating behavior GO:0042755 8 7 0,000 0,02127165 0,06471562 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02127165 0,06463512 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02127165 0,06455483 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02127165 0,06447474 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02127165 0,06439484 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02127165 0,06431515 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02127165 0,06423565 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02127165 0,06415634 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02127165 0,06407724 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02127165 0,06399832 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02127165 0,06391961 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02127165 0,06384108 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02127165 0,06376275 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02127165 0,06368461 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02127165 0,06360666 ! histone ubiquitination GO:0016574 9 7 0,000 0,02127165 0,0635289 ! regulation of meiosis GO:0040020 12 7 0,000 0,02127165 0,06345133 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02127165 0,06337395 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02127165 0,06329676 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02127165 0,06321976 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02127165 0,06314294 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02127165 0,06306631 ! transcription termination GO:0006353 14 7 0,000 0,02127165 0,06298987 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02127165 0,06291361 ! anaphase GO:0051322 18 7 0,000 0,02127165 0,06283753 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02127165 0,06276164 ! axonal fasciculation GO:0007413 19 7 0,000 0,02127165 0,06268593 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02127165 0,06261041 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02127165 0,06253507 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02127165 0,0624599 GO:0015991|ATP hydrolysis coupled proton transport, ! diuresis GO:0030146 12 7 0,000 0,02127165 0,06238492 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02127165 0,06231012 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02127165 0,0622355 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02127165 0,06216105 ! antibiotic transport GO:0042891 9 7 0,000 0,02127165 0,06208679 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02127165 0,0620127 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02127165 0,06193878 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02127165 0,06186505 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02127165 0,06179149 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02127165 0,0617181 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02127165 0,06164489 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02127165 0,06157185 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02127165 0,06149898 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02127165 0,06142629 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02127165 0,06135377 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02127165 0,06128141 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02127165 0,06120923 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02127165 0,06113722 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02127165 0,06106538 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02127165 0,06099371 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02127165 0,0609222 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02127165 0,06085087 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02127165 0,06077969 ! muscle adaptation GO:0043500 13 7 0,000 0,02127165 0,06070869 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02127165 0,06063785 ! retina homeostasis GO:0001895 12 7 0,000 0,02127165 0,06056718 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02127165 0,06049667 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02127165 0,06042632 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02127165 0,06035614 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,0223581 0,06336524 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 1,000 0,0223581 0,06329181 ! eye development GO:0001654 155 75 1,000 0,0223581 0,06321856 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,02291708 0,06472418 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,02291708 0,06464944 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,02291708 0,06457487 ! amine catabolic process GO:0009310 136 77 1,000 0,0234818 0,06608989 ! regulation of catabolic process GO:0009894 173 77 1,000 0,0234818 0,06601384 ! antigen processing and presentation GO:0019882 117 78 1,000 0,02405222 0,06753975 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02427363 0,06808321 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02427363 0,06800514 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02427363 0,06792724 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02427363 0,06784952 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02427363 0,06777197 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02427363 0,06769461 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02427363 0,06761742 ! male meiosis GO:0007140 9 8 0,000 0,02427363 0,06754041 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02427363 0,06746357 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02427363 0,06738691 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02427363 0,06731042 ! meiotic prophase I GO:0007128 14 8 0,000 0,02427363 0,0672341 ! response to zinc ion GO:0010043 12 8 0,000 0,02427363 0,06715796 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,02427363 0,06708199 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02427363 0,06700619 ! oligopeptide transport GO:0006857 16 8 0,000 0,02427363 0,06693056 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02427363 0,0668551 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02427363 0,06677982 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02427363 0,0667047 ! signal peptide processing GO:0006465 12 8 0,000 0,02427363 0,06662975 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02427363 0,06655497 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02427363 0,06648036 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02427363 0,06640591 ! succinate metabolic process GO:0006105 17 8 0,000 0,02427363 0,06633163 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02427363 0,06625752 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02427363 0,06618357 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02427363 0,06610979 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02427363 0,06603617 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02427363 0,06596271 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02427363 0,06588942 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02427363 0,06581629 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02427363 0,06574332 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02427363 0,06567052 ! reflex GO:0060004 17 8 0,000 0,02427363 0,06559787 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02427363 0,06552539 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02427363 0,06545307 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02427363 0,0653809 ! pigment granule organization GO:0048753 17 8 0,000 0,02427363 0,0653089 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02427363 0,06523705 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02427363 0,06516536 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02427363 0,06509383 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02427363 0,06502245 ! histidine catabolic process GO:0006548 10 8 0,000 0,02427363 0,06495124 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02427363 0,06488017 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02427363 0,06480927 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02427363 0,06473851 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,02427363 0,06466792 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02427363 0,06459747 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02427363 0,06452718 ! melanin metabolic process GO:0006582 17 8 0,000 0,02427363 0,06445704 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02427363 0,06438706 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02427363 0,06431722 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02427363 0,06424754 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02427363 0,06417801 ! macrophage activation GO:0042116 13 8 0,000 0,02427363 0,06410862 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02427363 0,06403939 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02427363 0,06397031 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02427363 0,06390138 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02427363 0,06383259 ! purine salvage GO:0043101 12 8 0,000 0,02427363 0,06376395 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02427363 0,06369547 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02427363 0,06362712 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02427363 0,06355893 ! osteoblast development GO:0002076 17 8 0,000 0,02427363 0,06349088 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02427363 0,06342297 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02427363 0,06335521 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02427363 0,0632876 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02427363 0,06322013 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02427363 0,0631528 ! response to UV-B GO:0010224 17 8 0,000 0,02427363 0,06308562 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02427363 0,06301857 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02427363 0,06295168 ! intermediate filament organization GO:0045109 12 8 0,000 0,02427363 0,06288492 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02427363 0,0628183 ! cellular extravasation GO:0045123 13 8 0,000 0,02427363 0,06275183 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02427363 0,06268549 ! response to antibiotic GO:0046677 11 8 0,000 0,02427363 0,0626193 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02427363 0,06255325 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02427363 0,06248733 ! DNA topological change GO:0006265 12 8 0,000 0,02427363 0,06242156 ! response to tropane GO:0014073 15 8 0,000 0,02427363 0,06235592 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02427363 0,06229042 ! melanosome transport GO:0032402 13 8 0,000 0,02427363 0,06222506 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,02427363 0,06215983 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02427363 0,06209474 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02427363 0,06202979 ! mast cell activation GO:0045576 14 8 0,000 0,02427363 0,06196497 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02427363 0,06190029 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02427363 0,06183574 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02427363 0,06177133 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02427363 0,06170705 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02427363 0,06164291 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02427363 0,0615789 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02427363 0,06151502 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,02427363 0,06145127 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02427363 0,06138766 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02427363 0,06132418 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02427363 0,06126082 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02427363 0,0611976 ! response to tumor cell GO:0002347 16 8 0,000 0,02427363 0,06113451 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02427363 0,06107155 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,02427363 0,06100872 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02427363 0,06094602 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02427363 0,06088345 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02427363 0,060821 ! hormone catabolic process GO:0042447 17 8 0,000 0,02427363 0,06075869 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02427363 0,0606965 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02427363 0,06063444 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02427363 0,0605725 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02427363 0,06051069 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02427363 0,06044901 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02427363 0,06038745 ! adult feeding behavior GO:0008343 10 8 0,000 0,02427363 0,06032602 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02427363 0,06026471 ! ATP catabolic process GO:0006200 11 8 0,000 0,02427363 0,06020353 ! blastocyst growth GO:0001832 19 8 0,000 0,02427363 0,06014247 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02427363 0,06008154 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02427363 0,06002073 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02427363 0,05996004 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02427363 0,05989947 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02427363 0,05983903 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02427363 0,05977871 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02427363 0,05971851 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02427363 0,05965843 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02427363 0,05959847 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02427363 0,05953863 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02427363 0,05947891 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02427363 0,05941932 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02427363 0,05935984 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02427363 0,05930048 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02427363 0,05924124 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02427363 0,05918211 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02427363 0,05912311 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,02462831 0,05992726 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,02462831 0,05986763 ! protein oligomerization GO:0051259 149 79 1,000 0,02462831 0,05980812 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,02521003 0,06115998 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,02521003 0,0610993 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,02521003 0,06103875 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,02639018 0,06383288 ! protein import into nucleus GO:0006606 174 82 1,000 0,02639018 0,06376974 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,02698854 0,06515118 ! nuclear import GO:0051170 177 83 1,000 0,02698854 0,06508686 ! inorganic anion transport GO:0015698 156 83 1,000 0,02698854 0,06502268 ! axon extension GO:0048675 16 9 0,000 0,02726649 0,06562761 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02726649 0,06556302 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02726649 0,06549855 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02726649 0,06543421 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02726649 0,06537 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02726649 0,06530591 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02726649 0,06524195 ! reproductive behavior GO:0019098 22 9 0,000 0,02726649 0,06517811 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02726649 0,0651144 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02726649 0,06505081 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02726649 0,06498734 ! RNA methylation GO:0001510 16 9 0,000 0,02726649 0,064924 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02726649 0,06486079 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02726649 0,06479769 ! artery development GO:0060840 25 9 0,000 0,02726649 0,06473472 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02726649 0,06467187 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02726649 0,06460914 ! equilibrioception GO:0050957 20 9 0,000 0,02726649 0,06454654 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02726649 0,06448405 ! chemosensory behavior GO:0007635 21 9 0,000 0,02726649 0,06442169 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02726649 0,06435945 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02726649 0,06429732 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02726649 0,06423532 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02726649 0,06417344 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02726649 0,06411167 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02726649 0,06405003 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02726649 0,0639885 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02726649 0,06392709 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02726649 0,0638658 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02726649 0,06380462 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02726649 0,06374357 ! protein targeting to ER GO:0045047 25 9 0,000 0,02726649 0,06368263 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02726649 0,0636218 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02726649 0,0635611 ! T cell selection GO:0045058 27 9 0,000 0,02726649 0,0635005 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,02726649 0,06344003 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02726649 0,06337967 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02726649 0,06331942 ! endosome organization GO:0007032 20 9 0,000 0,02726649 0,06325929 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02726649 0,06319927 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02726649 0,06313936 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02726649 0,06307957 ! mannose metabolic process GO:0006013 13 9 0,000 0,02726649 0,06301989 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02726649 0,06296033 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02726649 0,06290088 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02726649 0,06284154 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02726649 0,06278231 ! receptor clustering GO:0043113 20 9 0,000 0,02726649 0,06272319 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02726649 0,06266418 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02726649 0,06260529 ! retinol metabolic process GO:0042572 20 9 0,000 0,02726649 0,06254651 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02726649 0,06248783 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02726649 0,06242927 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02726649 0,06237081 ! macrophage differentiation GO:0030225 15 9 0,000 0,02726649 0,06231247 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02726649 0,06225423 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02726649 0,0621961 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02726649 0,06213809 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02726649 0,06208018 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02726649 0,06202237 ! response to amine stimulus GO:0014075 13 9 0,000 0,02726649 0,06196468 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02726649 0,06190709 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02726649 0,06184961 ! erythrocyte development GO:0048821 17 9 0,000 0,02726649 0,06179223 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02726649 0,06173497 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02726649 0,0616778 ! renal water homeostasis GO:0003091 15 9 0,000 0,02726649 0,06162075 ! postreplication repair GO:0006301 25 9 0,000 0,02726649 0,0615638 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02726649 0,06150695 ! icosanoid secretion GO:0032309 15 9 0,000 0,02726649 0,06145021 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02726649 0,06139357 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02726649 0,06133704 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02726649 0,06128061 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02726649 0,06122429 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02726649 0,06116807 ! sterol catabolic process GO:0016127 14 9 0,000 0,02726649 0,06111195 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02726649 0,06105594 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02726649 0,06100003 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02726649 0,06094422 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02726649 0,06088851 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02726649 0,0608329 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02726649 0,0607774 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02726649 0,06072199 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02726649 0,06066669 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02726649 0,06061149 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02726649 0,06055639 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02726649 0,06050139 ! purine base metabolic process GO:0006144 25 9 0,000 0,02726649 0,06044649 ! pigment granule transport GO:0051904 17 9 0,000 0,02726649 0,06039168 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02726649 0,06033698 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02726649 0,06028238 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02726649 0,06022787 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02726649 0,06017347 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02726649 0,06011916 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02726649 0,06006495 ! mitochondrion localization GO:0051646 18 9 0,000 0,02726649 0,06001084 ! negative regulation of growth GO:0045926 168 85 1,000 0,02820162 0,0620131 ! regulation of protein transport GO:0051223 165 87 1,000 0,02943628 0,0646698 GO:0070201|regulation of establishment of protein localization, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03025025 0,06639834 ! regulation of developmental growth GO:0048638 16 10 0,000 0,03025025 0,06633874 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,03025025 0,06627924 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03025025 0,06621985 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03025025 0,06616057 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03025025 0,06610139 ! associative learning GO:0008306 21 10 0,000 0,03025025 0,06604232 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,03025025 0,06598335 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03025025 0,06592449 ! phosphate transport GO:0006817 24 10 0,000 0,03025025 0,06586574 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03025025 0,06580709 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03025025 0,06574854 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03025025 0,06569009 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03025025 0,06563176 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03025025 0,06557352 ! social behavior GO:0035176 29 10 0,000 0,03025025 0,06551539 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03025025 0,06545736 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03025025 0,06539943 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03025025 0,06534161 ! androgen metabolic process GO:0008209 17 10 0,000 0,03025025 0,06528388 ! phospholipid efflux GO:0033700 19 10 0,000 0,03025025 0,06522626 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03025025 0,06516875 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03025025 0,06511133 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03025025 0,06505401 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03025025 0,0649968 ! lung alveolus development GO:0048286 26 10 0,000 0,03025025 0,06493968 ! pathogenesis GO:0009405 17 10 0,000 0,03025025 0,06488267 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03025025 0,06482575 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03025025 0,06476894 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03025025 0,06471222 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,03025025 0,06465561 ! endoderm development GO:0007492 18 10 0,000 0,03025025 0,06459909 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03025025 0,06454267 ! arginine catabolic process GO:0006527 17 10 0,000 0,03025025 0,06448635 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03025025 0,06443013 ! proline metabolic process GO:0006560 13 10 0,000 0,03025025 0,064374 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03025025 0,06431798 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03025025 0,06426205 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03025025 0,06420622 ! V(D)J recombination GO:0033151 34 10 0,000 0,03025025 0,06415048 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03025025 0,06409485 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03025025 0,0640393 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03025025 0,06398386 ! B cell proliferation GO:0042100 19 10 0,000 0,03025025 0,06392851 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03025025 0,06387326 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03025025 0,0638181 ! multicellular organism growth GO:0035264 19 10 0,000 0,03025025 0,06376303 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03025025 0,06370807 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03025025 0,06365319 ! ruffle organization GO:0031529 17 10 0,000 0,03025025 0,06359841 ! epithelial cell development GO:0002064 21 10 0,000 0,03025025 0,06354373 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03025025 0,06348914 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03025025 0,06343464 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03025025 0,06338024 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03025025 0,06332593 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03025025 0,06327171 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,03025025 0,06321758 ! motor axon guidance GO:0008045 22 10 0,000 0,03025025 0,06316355 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03025025 0,06310961 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03025025 0,06305577 ! protein heterooligomerization GO:0051291 17 10 0,000 0,03025025 0,06300201 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03025025 0,06294834 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03025025 0,06289477 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03025025 0,06284129 ! segment specification GO:0007379 15 10 0,000 0,03025025 0,0627879 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,03025025 0,0627346 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,03025025 0,06268139 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03025025 0,06262827 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03025025 0,06257524 ! response to dsRNA GO:0043331 23 10 0,000 0,03025025 0,0625223 ! DNA ligation GO:0006266 18 10 0,000 0,03025025 0,06246945 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03025025 0,06241669 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03025025 0,06236401 ! melanosome localization GO:0032400 16 10 0,000 0,03025025 0,06231143 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03025025 0,06225894 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03025025 0,06220653 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03025025 0,06215421 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03025025 0,06210198 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03025025 0,06204984 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03025025 0,06199778 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03025025 0,06194581 ! protein sumoylation GO:0016925 17 10 0,000 0,03025025 0,06189393 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03025025 0,06184214 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03025025 0,06179043 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03025025 0,06173881 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03025025 0,06168728 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03025025 0,06163583 ! salivary gland development GO:0007431 28 10 0,000 0,03025025 0,06158446 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03025025 0,06153319 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03025025 0,06148199 ! midbrain development GO:0030901 14 10 0,000 0,03025025 0,06143089 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03025025 0,06137986 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03025025 0,06132893 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03025025 0,06127807 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03025025 0,0612273 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03025025 0,06117662 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03025025 0,06112602 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03025025 0,0610755 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03025025 0,06102507 ! detection of calcium ion GO:0005513 24 10 0,000 0,03025025 0,06097472 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03025025 0,06092445 ! blastocyst formation GO:0001825 18 10 0,000 0,03025025 0,06087426 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03025025 0,06082416 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03025025 0,06077414 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03025025 0,0607242 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03025025 0,06067435 ! response to nicotine GO:0035094 20 10 0,000 0,03025025 0,06062457 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03025025 0,06057488 ! protein localization in nucleus GO:0034504 192 89 1,000 0,0306922 0,06140953 ! regulation of neurological system process GO:0031644 175 89 1,000 0,0306922 0,06135928 ! ossification GO:0001503 205 91 1,000 0,03196909 0,06385975 ! gland development GO:0048732 220 91 1,000 0,03196909 0,06380758 ! defense response to bacterium GO:0042742 112 91 1,000 0,03196909 0,06375549 ! bone development GO:0060348 206 92 1,000 0,0326153 0,06499117 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,03322494 0,06615202 ! respiratory burst GO:0045730 17 11 0,000 0,03322494 0,06609815 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,03322494 0,06604437 ! neuron fate specification GO:0048665 18 11 0,000 0,03322494 0,06599068 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03322494 0,06593707 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,03322494 0,06588355 ! thyroid gland development GO:0030878 26 11 0,000 0,03322494 0,06583011 ! synapsis GO:0007129 14 11 0,000 0,03322494 0,06577677 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03322494 0,06572351 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,03322494 0,06567033 ! response to pain GO:0048265 27 11 0,000 0,03322494 0,06561724 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03322494 0,06556424 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,03322494 0,06551132 ! blood vessel remodeling GO:0001974 30 11 0,000 0,03322494 0,06545849 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,03322494 0,06540575 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,03322494 0,06535308 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03322494 0,06530051 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03322494 0,06524801 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03322494 0,06519561 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03322494 0,06514328 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03322494 0,06509104 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03322494 0,06503889 ! L-serine metabolic process GO:0006563 21 11 0,000 0,03322494 0,06498681 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,03322494 0,06493482 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03322494 0,06488292 ! UV protection GO:0009650 20 11 0,000 0,03322494 0,06483109 ! adult heart development GO:0007512 16 11 0,000 0,03322494 0,06477935 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,03322494 0,0647277 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03322494 0,06467612 ! macroautophagy GO:0016236 19 11 0,000 0,03322494 0,06462463 ! temperature homeostasis GO:0001659 18 11 0,000 0,03322494 0,06457321 ! behavioral fear response GO:0001662 27 11 0,000 0,03322494 0,06452188 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03322494 0,06447064 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03322494 0,06441947 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,03322494 0,06436838 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,03322494 0,06431738 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03322494 0,06426645 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,03322494 0,06421561 ! regulation of organ growth GO:0046620 14 11 0,000 0,03322494 0,06416485 ! pigment granule localization GO:0051875 20 11 0,000 0,03322494 0,06411416 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03322494 0,06406356 ! vasoconstriction GO:0042310 20 11 0,000 0,03322494 0,06401304 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03322494 0,06396259 ! embryonic axis specification GO:0000578 19 11 0,000 0,03322494 0,06391223 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03322494 0,06386194 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03322494 0,06381174 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03322494 0,06376161 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03322494 0,06371156 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03322494 0,06366159 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03322494 0,0636117 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03322494 0,06356189 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,03322494 0,06351215 ! prophase GO:0051324 17 11 0,000 0,03322494 0,06346249 ! neuroblast proliferation GO:0007405 25 11 0,000 0,03322494 0,06341291 ! nucleosome positioning GO:0016584 15 11 0,000 0,03322494 0,06336341 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03322494 0,06331399 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03322494 0,06326464 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03322494 0,06321537 ! apical protein localization GO:0045176 18 11 0,000 0,03322494 0,06316617 ! acid secretion GO:0046717 20 11 0,000 0,03322494 0,06311705 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03322494 0,06306801 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03322494 0,06301905 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,03322494 0,06297016 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03322494 0,06292134 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03322494 0,0628726 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,03322494 0,06282394 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,03322494 0,06277535 ! cholesterol efflux GO:0033344 21 11 0,000 0,03322494 0,06272684 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03322494 0,0626784 ! oocyte development GO:0048599 20 11 0,000 0,03322494 0,06263004 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,03322494 0,06258175 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,03322494 0,06253354 ! embryonic gut development GO:0048566 19 11 0,000 0,03322494 0,0624854 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03322494 0,06243733 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,03322494 0,06238934 ! activation of innate immune response GO:0002218 16 11 0,000 0,03322494 0,06234142 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03322494 0,06229358 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,03322494 0,06224581 ! lysogeny GO:0030069 22 11 0,000 0,03322494 0,06219811 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03322494 0,06215048 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,03322494 0,06210293 ! sequestering of metal ion GO:0051238 15 11 0,000 0,03322494 0,06205545 ! nucleus localization GO:0051647 22 11 0,000 0,03322494 0,06200804 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,03326664 0,06203847 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,03392307 0,06321439 ! regulation of protein localization GO:0032880 188 97 1,000 0,03592256 0,06688934 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,03619059 0,0673371 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,03619059 0,06728586 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,03619059 0,06723469 ! virus-host interaction GO:0019048 30 12 0,000 0,03619059 0,0671836 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,03619059 0,06713259 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,03619059 0,06708165 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03619059 0,06703079 ! protein complex disassembly GO:0043241 28 12 0,000 0,03619059 0,06698001 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03619059 0,06692931 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,03619059 0,06687868 ! hippocampus development GO:0021766 29 12 0,000 0,03619059 0,06682813 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,03619059 0,06677766 ! T cell proliferation GO:0042098 32 12 0,000 0,03619059 0,06672726 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03619059 0,06667694 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,03619059 0,06662669 ! ventral spinal cord development GO:0021517 25 12 0,000 0,03619059 0,06657652 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,03619059 0,06652642 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,03619059 0,0664764 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,03619059 0,06642646 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,03619059 0,06637659 ! polyamine metabolic process GO:0006595 18 12 0,000 0,03619059 0,06632679 ! focal adhesion formation GO:0048041 37 12 0,000 0,03619059 0,06627707 ! mitotic spindle organization GO:0007052 23 12 0,000 0,03619059 0,06622743 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,03619059 0,06617786 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,03619059 0,06612836 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,03619059 0,06607894 ! lipid digestion GO:0044241 21 12 0,000 0,03619059 0,06602959 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,03619059 0,06598031 ! entry into host cell GO:0030260 34 12 0,000 0,03619059 0,06593111 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03619059 0,06588198 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,03619059 0,06583292 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,03619059 0,06578394 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03619059 0,06573503 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,03619059 0,06568619 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,03619059 0,06563743 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,03619059 0,06558874 ! snRNA metabolic process GO:0016073 30 12 0,000 0,03619059 0,06554012 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,03619059 0,06549157 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,03619059 0,06544309 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03619059 0,06539469 ! cranial nerve development GO:0021545 23 12 0,000 0,03619059 0,06534635 ! fucose catabolic process GO:0019317 25 12 0,000 0,03619059 0,06529809 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,03619059 0,0652499 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,03619059 0,06520178 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03619059 0,06515373 ! zymogen activation GO:0031638 18 12 0,000 0,03619059 0,06510576 ! T cell homeostasis GO:0043029 28 12 0,000 0,03619059 0,06505785 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,03619059 0,06501001 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,03619059 0,06496225 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,03619059 0,06491455 ! oocyte differentiation GO:0009994 21 12 0,000 0,03619059 0,06486692 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,03619059 0,06481937 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,03619059 0,06477188 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,03619059 0,06472446 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,03619059 0,06467712 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,03619059 0,06462984 ! defense response to fungus GO:0050832 15 12 0,000 0,03619059 0,06458263 ! lamellipodium assembly GO:0030032 24 12 0,000 0,03619059 0,06453549 ! response to cold GO:0009409 17 12 0,000 0,03619059 0,06448841 ! establishment of cell polarity GO:0030010 21 12 0,000 0,03619059 0,06444141 ! regulation of synapse organization GO:0050807 18 12 0,000 0,03619059 0,06439448 ! leukocyte differentiation GO:0002521 232 98 1,000 0,036599 0,06507377 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,03796657 0,06745625 GO:0060538|skeletal muscle organ development, ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03914723 0,0695034 ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03914723 0,06945293 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03914723 0,06940253 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03914723 0,0693522 ! peroxisomal transport GO:0043574 28 13 0,000 0,03914723 0,06930194 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03914723 0,06925176 ! cartilage condensation GO:0001502 22 13 0,000 0,03914723 0,06920165 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,03914723 0,06915161 ! organelle fusion GO:0048284 36 13 0,000 0,03914723 0,06910165 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03914723 0,06905175 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,03914723 0,06900193 ! endocrine pancreas development GO:0031018 25 13 0,000 0,03914723 0,06895218 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,03914723 0,06890251 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03914723 0,0688529 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03914723 0,06880337 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03914723 0,0687539 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03914723 0,06870451 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03914723 0,06865519 ! methionine metabolic process GO:0006555 31 13 0,000 0,03914723 0,06860594 ! plasma membrane organization GO:0007009 27 13 0,000 0,03914723 0,06855676 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03914723 0,06850765 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03914723 0,06845861 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03914723 0,06840964 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,03914723 0,06836074 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,03914723 0,06831191 ! cytokine metabolic process GO:0042107 24 13 0,000 0,03914723 0,06826316 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,03914723 0,06821447 ! exocrine system development GO:0035272 34 13 0,000 0,03914723 0,06816584 ! asymmetric protein localization GO:0008105 24 13 0,000 0,03914723 0,06811729 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,03914723 0,06806881 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,03914723 0,0680204 ! L-glutamate transport GO:0015813 30 13 0,000 0,03914723 0,06797205 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03914723 0,06792378 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03914723 0,06787557 ! protein homotetramerization GO:0051289 24 13 0,000 0,03914723 0,06782743 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03914723 0,06777936 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03914723 0,06773136 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,03914723 0,06768343 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03914723 0,06763556 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03914723 0,06758776 ! histone methylation GO:0016571 29 13 0,000 0,03914723 0,06754003 ! chromatin silencing GO:0006342 29 13 0,000 0,03914723 0,06749236 ! gland morphogenesis GO:0022612 31 13 0,000 0,03914723 0,06744477 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,03914723 0,06739724 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,03914723 0,06734977 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,03914723 0,06730238 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,03914723 0,06725505 ! spleen development GO:0048536 24 13 0,000 0,03914723 0,06720779 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,03914723 0,06716059 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03914723 0,06711346 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,03914723 0,0670664 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03914723 0,0670194 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,03914723 0,06697247 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03914723 0,0669256 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03914723 0,0668788 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03914723 0,06683206 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03914723 0,06678539 ! insulin secretion GO:0030073 24 13 0,000 0,03914723 0,06673879 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03914723 0,06669225 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,03914723 0,06664577 ! acrosome reaction GO:0007340 19 13 0,000 0,03914723 0,06659936 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03914723 0,06655301 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03914723 0,06650673 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,04209488 0,07146476 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,04209488 0,07141513 ! water transport GO:0006833 21 14 0,000 0,04209488 0,07136557 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,04209488 0,07131608 ! non-recombinational repair GO:0000726 29 14 0,000 0,04209488 0,07126666 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,04209488 0,07121731 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,04209488 0,07116802 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,04209488 0,0711188 ! RNA polyadenylation GO:0043631 32 14 0,000 0,04209488 0,07106965 ! lipid localization GO:0010876 32 14 0,000 0,04209488 0,07102057 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,04209488 0,07097156 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,04209488 0,07092261 ! regulated secretory pathway GO:0045055 24 14 0,000 0,04209488 0,07087373 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,04209488 0,07082492 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,04209488 0,07077618 ! arginine metabolic process GO:0006525 21 14 0,000 0,04209488 0,0707275 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,04209488 0,07067889 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,04209488 0,07063035 ! regulation of heart rate GO:0002027 25 14 0,000 0,04209488 0,07058187 ! fear response GO:0042596 34 14 0,000 0,04209488 0,07053346 ! organic alcohol transport GO:0015850 29 14 0,000 0,04209488 0,07048512 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,04209488 0,07043684 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,04209488 0,07038863 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04209488 0,07034049 ! neutral amino acid transport GO:0015804 28 14 0,000 0,04209488 0,07029241 ! bone mineralization GO:0030282 18 14 0,000 0,04209488 0,07024439 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,04209488 0,07019644 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,04209488 0,07014856 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,04209488 0,07010074 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,04209488 0,07005299 ! regulation of cellular pH GO:0030641 27 14 0,000 0,04209488 0,0700053 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,04209488 0,06995768 ! ribosome assembly GO:0042255 18 14 0,000 0,04209488 0,06991012 ! cerebellum development GO:0021549 23 14 0,000 0,04209488 0,06986263 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,04209488 0,0698152 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,04209488 0,06976784 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,04209488 0,06972054 ! response to gamma radiation GO:0010332 30 14 0,000 0,04209488 0,0696733 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,04209488 0,06962613 ! NADP metabolic process GO:0006739 24 14 0,000 0,04209488 0,06957902 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,04209488 0,06953197 ! oxygen transport GO:0015671 22 14 0,000 0,04209488 0,06948499 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04209488 0,06943808 ! male genitalia development GO:0030539 26 14 0,000 0,04209488 0,06939122 ! regulation of RNA stability GO:0043487 33 14 0,000 0,04209488 0,06934443 ! regulation of axon extension GO:0030516 43 14 0,000 0,04209488 0,0692977 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,04209488 0,06925104 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,04209488 0,06920443 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04503357 0,07398588 ! reproductive cellular process GO:0048610 22 15 0,000 0,04503357 0,07393616 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04503357 0,07388651 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,04503357 0,07383692 ! superoxide anion generation GO:0042554 22 15 0,000 0,04503357 0,0737874 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,04503357 0,07373794 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,04503357 0,07368855 ! copper ion transport GO:0006825 22 15 0,000 0,04503357 0,07363923 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,04503357 0,07358997 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,04503357 0,07354078 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,04503357 0,07349166 ! sulfate transport GO:0008272 27 15 0,000 0,04503357 0,0734426 ! response to cAMP GO:0051591 25 15 0,000 0,04503357 0,0733936 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,04503357 0,07334467 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,04503357 0,07329581 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,04503357 0,07324701 ! response to hexose stimulus GO:0009746 25 15 0,000 0,04503357 0,07319828 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,04503357 0,07314961 ! vesicle coating GO:0006901 38 15 0,000 0,04503357 0,073101 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,04503357 0,07305246 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,04503357 0,07300399 ! regulation of exocytosis GO:0017157 26 15 0,000 0,04503357 0,07295558 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,04503357 0,07290723 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,04503357 0,07285895 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,04503357 0,07281073 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,04503357 0,07276257 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,04503357 0,07271448 ! regulation of vasodilation GO:0042312 27 15 0,000 0,04503357 0,07266645 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,04503357 0,07261849 ! histone deacetylation GO:0016575 24 15 0,000 0,04503357 0,07257059 ! water homeostasis GO:0030104 28 15 0,000 0,04503357 0,07252275 ! cofactor transport GO:0051181 30 15 0,000 0,04503357 0,07247497 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04503357 0,07242726 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,04503357 0,07237961 ! intestinal absorption GO:0050892 31 15 0,000 0,04503357 0,07233202 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04503357 0,0722845 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,04503357 0,07223704 ! heme biosynthetic process GO:0006783 33 15 0,000 0,04503357 0,07218964 ! cell killing GO:0001906 32 15 0,000 0,04503357 0,0721423 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,04503357 0,07209503 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,04503357 0,07204781 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,04503357 0,07200066 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,04503357 0,07195357 ! actin filament polymerization GO:0030041 27 15 0,000 0,04503357 0,07190654 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,04503357 0,07185957 ! positive regulation of cell size GO:0045793 29 16 0,000 0,04796333 0,0764846 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,04796333 0,07643471 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,04796333 0,07638488 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,04796333 0,07633512 ! bone remodeling GO:0046849 28 16 0,000 0,04796333 0,07628542 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,04796333 0,07623579 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,04796333 0,07618622 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04796333 0,07613672 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,04796333 0,07608728 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,04796333 0,0760379 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,04796333 0,07598859 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,04796333 0,07593934 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,04796333 0,07589016 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,04796333 0,07584104 ! protein polyubiquitination GO:0000209 41 16 0,000 0,04796333 0,07579198 ! glutamate metabolic process GO:0006536 25 16 0,000 0,04796333 0,07574299 ! pituitary gland development GO:0021983 30 16 0,000 0,04796333 0,07569406 ! response to osmotic stress GO:0006970 27 16 0,000 0,04796333 0,07564519 ! lysosomal transport GO:0007041 31 16 0,000 0,04796333 0,07559639 ! fructose metabolic process GO:0006000 25 16 0,000 0,04796333 0,07554765 ! L-amino acid transport GO:0015807 33 16 0,000 0,04796333 0,07549897 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04796333 0,07545036 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04796333 0,07540181 ! intermediate filament-based process GO:0045103 36 16 0,000 0,04796333 0,07535332 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,04796333 0,07530489 ! negative regulation of immune response GO:0050777 38 16 0,000 0,04796333 0,07525652 ! axon cargo transport GO:0008088 46 16 0,000 0,04796333 0,07520822 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,04796333 0,07515998 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,04796333 0,0751118 ! DNA replication initiation GO:0006270 28 16 0,000 0,04796333 0,07506368 ! neuron recognition GO:0008038 40 16 0,000 0,04796333 0,07501562 ! mRNA splice site selection GO:0006376 44 16 0,000 0,04796333 0,07496763 ! tissue regeneration GO:0042246 27 16 0,000 0,04796333 0,0749197 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,04796333 0,07487182 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,04796333 0,07482401 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,04796333 0,07477626 ! biomineral formation GO:0031214 22 16 0,000 0,04796333 0,07472858 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,04796333 0,07468095 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,04796333 0,07463338 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,04796333 0,07458587 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04796333 0,07453843 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,04796333 0,07449104 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,04796333 0,07444371 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,04796333 0,07439645 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,04796333 0,07434924 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04796333 0,0743021 ! peptide hormone processing GO:0016486 27 16 0,000 0,04796333 0,07425501 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,05088418 0,07872707 ! metencephalon development GO:0022037 32 17 0,000 0,05088418 0,07867724 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,05088418 0,07862748 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,05088418 0,07857778 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,05088418 0,07852814 ! signal complex assembly GO:0007172 47 17 0,000 0,05088418 0,07847856 ! filopodium assembly GO:0046847 42 17 0,000 0,05088418 0,07842905 ! endothelial cell migration GO:0043542 31 17 0,000 0,05088418 0,0783796 ! gene silencing by RNA GO:0031047 38 17 0,000 0,05088418 0,07833021 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,05088418 0,07828088 ! glial cell development GO:0021782 28 17 0,000 0,05088418 0,07823162 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,05088418 0,07818242 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,05088418 0,07813328 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,05088418 0,0780842 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,05088418 0,07803518 ! myoblast differentiation GO:0045445 50 17 0,000 0,05088418 0,07798623 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,05088418 0,07793733 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,05088418 0,0778885 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,05088418 0,07783973 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,05088418 0,07779102 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,05088418 0,07774237 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,05088418 0,07769378 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,05088418 0,07764525 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,05088418 0,07759678 ! membrane budding GO:0006900 42 17 0,000 0,05088418 0,07754837 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,05088418 0,07750003 ! regulation of protein binding GO:0043393 33 17 0,000 0,05088418 0,07745174 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,05088418 0,07740352 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,05088418 0,07735535 ! genitalia development GO:0048806 32 17 0,000 0,05088418 0,07730724 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,05088418 0,0772592 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,05088418 0,07721121 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,05088418 0,07716328 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,05088418 0,07711541 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,05088418 0,0770676 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,05088418 0,07701985 ! steroid catabolic process GO:0006706 34 17 0,000 0,05088418 0,07697216 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,05088418 0,07692453 ! gas transport GO:0015669 26 17 0,000 0,05088418 0,07687696 ! organic cation transport GO:0015695 32 17 0,000 0,05088418 0,07682945 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,05088418 0,07678199 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,05088418 0,0767346 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,05088418 0,07668726 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,05379615 0,08102589 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,05379615 0,08097597 ! limbic system development GO:0021761 40 18 0,000 0,05379615 0,0809261 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05379615 0,0808763 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,05379615 0,08082656 ! adult walking behavior GO:0007628 36 18 0,000 0,05379615 0,08077689 ! patterning of blood vessels GO:0001569 43 18 0,000 0,05379615 0,08072727 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,05379615 0,08067771 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,05379615 0,08062822 ! centrosome cycle GO:0007098 26 18 0,000 0,05379615 0,08057878 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,05379615 0,08052941 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,05379615 0,08048009 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,05379615 0,08043084 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05379615 0,08038165 ! response to retinoic acid GO:0032526 31 18 0,000 0,05379615 0,08033251 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,05379615 0,08028344 ! DNA integration GO:0015074 32 18 0,000 0,05379615 0,08023443 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,05379615 0,08018547 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,05379615 0,08013658 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,05379615 0,08008775 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,05379615 0,08003897 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,05379615 0,07999026 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,05379615 0,0799416 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,05379615 0,079893 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,05379615 0,07984447 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,05379615 0,07979599 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,05379615 0,07974757 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,05379615 0,07969921 ! nerve development GO:0021675 34 18 0,000 0,05379615 0,0796509 ! defense response to virus GO:0051607 43 18 0,000 0,05379615 0,07960266 ! microspike assembly GO:0030035 46 18 0,000 0,05379615 0,07955447 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,05379615 0,07950635 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,05379615 0,07945828 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,05669927 0,08369566 ! positive regulation of translation GO:0045727 31 19 0,000 0,05669927 0,08364512 ! negative regulation of defense response GO:0031348 27 19 0,000 0,05669927 0,08359464 ! neuron maturation GO:0042551 46 19 0,000 0,05669927 0,08354422 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,05669927 0,08349386 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,05669927 0,08344356 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,05669927 0,08339333 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,05669927 0,08334315 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,05669927 0,08329303 ! inositol metabolic process GO:0006020 33 19 0,000 0,05669927 0,08324298 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05669927 0,08319298 ! memory GO:0007613 34 19 0,000 0,05669927 0,08314305 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,05669927 0,08309317 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,05669927 0,08304335 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,05669927 0,0829936 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,05669927 0,0829439 ! cerebral cortex development GO:0021987 40 19 0,000 0,05669927 0,08289426 ! pigmentation during development GO:0048066 42 19 0,000 0,05669927 0,08284468 ! response to vitamin A GO:0033189 32 19 0,000 0,05669927 0,08279517 ! heme metabolic process GO:0042168 40 19 0,000 0,05669927 0,08274571 ! neuromuscular junction development GO:0007528 43 19 0,000 0,05669927 0,08269631 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,05669927 0,08264696 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,05669927 0,08259768 ! response to fungus GO:0009620 26 19 0,000 0,05669927 0,08254846 ! peptide cross-linking GO:0018149 39 19 0,000 0,05669927 0,08249929 ! protein export from nucleus GO:0006611 40 19 0,000 0,05669927 0,08245019 ! heart process GO:0003015 32 19 0,000 0,05669927 0,08240114 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,05669927 0,08235215 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,05669927 0,08230322 ! visual learning GO:0008542 38 19 0,000 0,05669927 0,08225434 ! cellular pigmentation GO:0033059 37 19 0,000 0,05669927 0,08220553 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,05669927 0,08215677 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,05669927 0,08210807 ! vitamin transport GO:0051180 31 19 0,000 0,05669927 0,08205943 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,05669927 0,08201084 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,05669927 0,08196232 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,05669927 0,08191385 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,05669927 0,08186543 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,05669927 0,08181708 ! cilium assembly GO:0042384 38 19 0,000 0,05669927 0,08176878 ! peptide hormone secretion GO:0030072 32 19 0,000 0,05669927 0,08172054 ! protein secretion GO:0009306 45 20 0,000 0,05959356 0,08584143 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,05959356 0,08579085 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,05959356 0,08574033 ! positive regulation of ossification GO:0045778 50 20 0,000 0,05959356 0,08568986 ! skin development GO:0043588 42 20 0,000 0,05959356 0,08563945 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,05959356 0,08558911 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,05959356 0,08553882 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,05959356 0,08548859 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,05959356 0,08543842 ! response to vitamin GO:0033273 36 20 0,000 0,05959356 0,08538831 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,05959356 0,08533826 ! bile acid metabolic process GO:0008206 34 20 0,000 0,05959356 0,08528827 ! response to alkaloid GO:0043279 38 20 0,000 0,05959356 0,08523833 ! retinoid metabolic process GO:0001523 34 20 0,000 0,05959356 0,08518846 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,05959356 0,08513864 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,05959356 0,08508888 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,05959356 0,08503918 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,05959356 0,08498953 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,05959356 0,08493995 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,05959356 0,08489042 ! actin filament bundle formation GO:0051017 47 20 0,000 0,05959356 0,08484095 ! body fluid secretion GO:0007589 33 20 0,000 0,05959356 0,08479154 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,05959356 0,08474218 ! peptide secretion GO:0002790 38 20 0,000 0,05959356 0,08469289 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,05959356 0,08464365 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,05959356 0,08459446 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,05959356 0,08454534 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,05959356 0,08449627 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,05959356 0,08444726 ! cell-cell junction organization GO:0045216 43 20 0,000 0,05959356 0,0843983 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,05959356 0,0843494 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,05959356 0,08430056 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,05959356 0,08425178 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,05959356 0,08420305 ! regulation of glucose import GO:0046324 30 20 0,000 0,05959356 0,08415438 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,05959356 0,08410576 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,05959356 0,0840572 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,05959356 0,0840087 ! negative regulation of translation GO:0017148 32 20 0,000 0,05959356 0,08396025 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,05959356 0,08391186 ! regulation of cell killing GO:0031341 46 21 0,000 0,06247906 0,08792416 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,06247906 0,08787354 ! hormone secretion GO:0046879 39 21 0,000 0,06247906 0,08782298 ! lipid phosphorylation GO:0046834 43 21 0,000 0,06247906 0,08777248 ! cAMP metabolic process GO:0046058 41 21 0,000 0,06247906 0,08772203 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,06247906 0,08767165 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,06247906 0,08762132 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,06247906 0,08757105 ! ovarian follicle development GO:0001541 39 21 0,000 0,06247906 0,08752083 ! smooth muscle contraction GO:0006939 48 21 0,000 0,06247906 0,08747068 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,06247906 0,08742058 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,06247906 0,08737054 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,06247906 0,08732056 ! plasma membrane fusion GO:0045026 33 21 0,000 0,06247906 0,08727063 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,06247906 0,08722076 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,06247906 0,08717095 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,06247906 0,0871212 ! sensory perception of pain GO:0019233 33 21 0,000 0,06247906 0,0870715 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,06247906 0,08702186 ! diencephalon development GO:0021536 36 21 0,000 0,06247906 0,08697227 ! collagen fibril organization GO:0030199 62 21 0,000 0,06247906 0,08692274 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,06247906 0,08687327 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,06247906 0,08682385 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,06247906 0,08677449 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,06247906 0,08672519 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,06247906 0,08667594 ! collagen catabolic process GO:0030574 29 21 0,000 0,06247906 0,08662675 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,06247906 0,08657761 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,06247906 0,08652853 ! sperm-egg recognition GO:0035036 23 21 0,000 0,06247906 0,08647951 ! actin filament-based movement GO:0030048 47 21 0,000 0,06247906 0,08643054 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,06247906 0,08638163 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,06535578 0,09030779 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,06535578 0,09025674 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,06535578 0,09020574 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,06535578 0,09015481 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,06535578 0,09010393 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,06535578 0,09005311 ! microtubule-based transport GO:0010970 59 22 0,000 0,06535578 0,09000235 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,06535578 0,08995164 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,06535578 0,08990099 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,06535578 0,0898504 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,06535578 0,08979987 ! cellular response to starvation GO:0009267 37 22 0,000 0,06535578 0,08974939 ! vacuolar transport GO:0007034 41 22 0,000 0,06535578 0,08969897 ! central nervous system neuron development GO:0021954 47 22 0,000 0,06535578 0,08964861 ! fucose metabolic process GO:0006004 44 22 0,000 0,06535578 0,0895983 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,06535578 0,08954805 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,06535578 0,08949785 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,06535578 0,08944771 ! ureteric bud development GO:0001657 50 22 0,000 0,06535578 0,08939763 ! cell aging GO:0007569 48 22 0,000 0,06535578 0,0893476 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,06535578 0,08929763 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,06535578 0,08924772 ! cytolysis GO:0019835 27 22 0,000 0,06535578 0,08919786 ! renal system process GO:0003014 42 22 0,000 0,06535578 0,08914805 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,06535578 0,08909831 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,06535578 0,08904861 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,06535578 0,08899898 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,06535578 0,0889494 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,06535578 0,08889987 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,06535578 0,0888504 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,06535578 0,08880098 ! sarcomere organization GO:0045214 32 22 0,000 0,06535578 0,08875162 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,06535578 0,08870231 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,06535578 0,08865306 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,06535578 0,08860387 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,06535578 0,08855472 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,06535578 0,08850564 ! gut development GO:0048565 44 22 0,000 0,06535578 0,0884566 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,06535578 0,08840762 ! protein stabilization GO:0050821 41 22 0,000 0,06535578 0,0883587 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,06822375 0,09218508 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,06822375 0,09213412 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,06822375 0,09208322 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,06822375 0,09203237 ! gluconeogenesis GO:0006094 38 23 0,000 0,06822375 0,09198158 ! glycerol metabolic process GO:0006071 40 23 0,000 0,06822375 0,09193085 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,06822375 0,09188017 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,06822375 0,09182955 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,06822375 0,09177898 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,06822375 0,09172847 ! regeneration GO:0031099 42 23 0,000 0,06822375 0,09167801 ! axis specification GO:0009798 43 23 0,000 0,06822375 0,09162761 ! visual behavior GO:0007632 46 23 0,000 0,06822375 0,09157727 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,06822375 0,09152698 ! response to ethanol GO:0045471 47 23 0,000 0,06822375 0,09147675 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,06822375 0,09142657 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,06822375 0,09137644 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,06822375 0,09132637 ! peroxisome organization GO:0007031 43 23 0,000 0,06822375 0,09127636 ! lysosome organization GO:0007040 47 23 0,000 0,06822375 0,0912264 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,06822375 0,09117649 ! vesicle targeting GO:0006903 49 23 0,000 0,06822375 0,09112664 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,06822375 0,09107685 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,06822375 0,09102711 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,06822375 0,09097742 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,06822375 0,09092778 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,06822375 0,09087821 ! DNA modification GO:0006304 36 23 0,000 0,06822375 0,09082868 ! fatty acid transport GO:0015908 47 23 0,000 0,06822375 0,09077921 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,06822375 0,09072979 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,06822375 0,09068043 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,06822375 0,09063112 ! hormone transport GO:0009914 41 23 0,000 0,06822375 0,09058186 ! cell-cell recognition GO:0009988 28 23 0,000 0,06822375 0,09053266 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,06822375 0,09048351 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,06822375 0,09043442 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,06822375 0,09038537 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,07108301 0,09412238 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,07108301 0,09407139 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,07108301 0,09402046 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,07108301 0,09396958 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,07108301 0,09391876 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,07108301 0,09386799 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,07108301 0,09381728 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,07108301 0,09376663 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,07108301 0,09371602 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,07108301 0,09366548 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,07108301 0,09361498 ! sex determination GO:0007530 48 24 0,000 0,07108301 0,09356454 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,07108301 0,09351416 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,07108301 0,09346383 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,07108301 0,09341355 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,07108301 0,09336333 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,07108301 0,09331316 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,07108301 0,09326305 ! membrane depolarization GO:0051899 45 24 0,000 0,07108301 0,09321298 ! pallium development GO:0021543 56 24 0,000 0,07108301 0,09316298 ! oogenesis GO:0048477 44 24 0,000 0,07108301 0,09311302 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,07108301 0,09306312 ! platelet activation GO:0030168 41 24 0,000 0,07108301 0,09301328 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,07108301 0,09296349 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,07108301 0,09291375 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,07108301 0,09286406 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,07108301 0,09281443 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,07108301 0,09276485 ! regulation of amine transport GO:0051952 41 24 0,000 0,07108301 0,09271532 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,07393357 0,09638192 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,07393357 0,09633051 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,07393357 0,09627916 ! leukocyte adhesion GO:0007159 55 25 0,000 0,07393357 0,09622787 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,07393357 0,09617663 ! phototransduction GO:0007602 37 25 0,000 0,07393357 0,09612545 ! keratinization GO:0031424 37 25 0,000 0,07393357 0,09607432 ! vasculogenesis GO:0001570 49 25 0,000 0,07393357 0,09602324 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,07393357 0,09597222 ! vacuole organization GO:0007033 49 25 0,000 0,07393357 0,09592125 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,07393357 0,09587034 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,07393357 0,09581948 ! receptor metabolic process GO:0043112 53 25 0,000 0,07393357 0,09576867 ! chromosome condensation GO:0030261 48 25 0,000 0,07393357 0,09571792 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,07393357 0,09566722 ! regulation of behavior GO:0050795 48 25 0,000 0,07393357 0,09561658 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,07393357 0,09556599 ! interaction with host GO:0051701 66 25 0,000 0,07393357 0,09551545 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,07393357 0,09546496 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,07393357 0,09541453 ! immunoglobulin production GO:0002377 62 25 0,000 0,07393357 0,09536416 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,07393357 0,09531383 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,07393357 0,09526356 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,07393357 0,09521334 ! liver development GO:0001889 55 25 0,000 0,07393357 0,09516318 ! protein tetramerization GO:0051262 57 25 0,000 0,07393357 0,09511307 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,07677546 0,09871708 ! myelination GO:0042552 50 26 0,000 0,07677546 0,09866516 ! initiation of viral infection GO:0019059 60 26 0,000 0,07677546 0,09861328 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,07677546 0,09856146 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,07677546 0,0985097 ! molting cycle process GO:0022404 52 26 0,000 0,07677546 0,09845798 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,07677546 0,09840633 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,07677546 0,09835472 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,07677546 0,09830318 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,07677546 0,09825168 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,07677546 0,09820024 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,07677546 0,09814885 ! digestive system process GO:0022600 49 26 0,000 0,07677546 0,09809752 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,07677546 0,09804624 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,07677546 0,09799502 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,07677546 0,09794384 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,07677546 0,09789272 ! osteoblast differentiation GO:0001649 63 26 0,000 0,07677546 0,09784166 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,07677546 0,09779065 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,07677546 0,09773969 ! negative regulation of cell development GO:0010721 83 26 0,000 0,07677546 0,09768878 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,07677546 0,09763793 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,07677546 0,09758713 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,07677546 0,09753638 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,07677546 0,09748569 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,07677546 0,09743504 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,07677546 0,09738446 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,07677546 0,09733392 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,07677546 0,09728343 ! blastocyst development GO:0001824 50 26 0,000 0,07677546 0,097233 ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,07677546 0,09718262 ! neural tube closure GO:0001843 58 26 0,000 0,07677546 0,09713229 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,07677546 0,09708202 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,07677546 0,0970318 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,07677546 0,09698162 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,07960872 0,10050858 ! embryonic pattern specification GO:0009880 49 27 0,000 0,07960872 0,10045666 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,07960872 0,1004048 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,07960872 0,10035299 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,07960872 0,10030124 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,07960872 0,10024953 ! superoxide metabolic process GO:0006801 41 27 0,000 0,07960872 0,10019789 ! tube lumen formation GO:0035148 59 27 0,000 0,07960872 0,10014629 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,07960872 0,10009475 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,07960872 0,10004326 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,07960872 0,09999182 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,07960872 0,09994044 ! response to starvation GO:0042594 47 27 0,000 0,07960872 0,09988911 ! response to toxin GO:0009636 49 27 0,000 0,07960872 0,09983783 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,07960872 0,09978661 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,07960872 0,09973543 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,07960872 0,09968431 ! leukocyte proliferation GO:0070661 59 27 0,000 0,07960872 0,09963325 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,07960872 0,09958223 ! neuron fate commitment GO:0048663 52 28 0,000 0,08243336 0,10306279 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,08243336 0,10301007 ! vesicle docking GO:0048278 55 28 0,000 0,08243336 0,10295741 ! circadian rhythm GO:0007623 56 28 0,000 0,08243336 0,1029048 ! dendrite development GO:0016358 67 28 0,000 0,08243336 0,10285224 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,08243336 0,10279974 ! fat cell differentiation GO:0045444 57 28 0,000 0,08243336 0,10274729 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,08243336 0,10269489 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,08243336 0,10264255 ! base-excision repair GO:0006284 41 28 0,000 0,08243336 0,10259026 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,08243336 0,10253803 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,08243336 0,10248585 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,08243336 0,10243372 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,08243336 0,10238164 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,08243336 0,10232962 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,08243336 0,10227765 ! glutathione metabolic process GO:0006749 42 28 0,000 0,08243336 0,10222573 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,08243336 0,10217386 ! lipid oxidation GO:0034440 48 28 0,000 0,08243336 0,10212205 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,08243336 0,10207029 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,0852494 0,10550369 ! translational initiation GO:0006413 66 29 0,000 0,0852494 0,10545027 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,0852494 0,10539691 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,0852494 0,1053436 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,0852494 0,10529034 ! autophagy GO:0006914 47 29 0,000 0,0852494 0,10523714 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,0852494 0,10518399 ! primary neural tube formation GO:0014020 61 29 0,000 0,0852494 0,10513089 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,0852494 0,10507785 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,0852494 0,10502486 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,0852494 0,10497192 ! synaptogenesis GO:0007416 46 29 0,000 0,0852494 0,10491904 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,0852494 0,10486621 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,0852494 0,10481343 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,0852494 0,10476071 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,0852494 0,10470804 ! phenol metabolic process GO:0018958 56 30 0,000 0,08805689 0,108102 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,08805689 0,1080477 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,08805689 0,10799346 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,08805689 0,10793928 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,08805689 0,10788514 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,08805689 0,10783107 ! acute-phase response GO:0006953 50 30 0,000 0,08805689 0,10777704 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,08805689 0,10772307 ! myofibril assembly GO:0030239 50 30 0,000 0,08805689 0,10766916 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,08805689 0,1076153 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,08805689 0,10756149 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,08805689 0,10750773 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,08805689 0,10745403 ! phospholipid transport GO:0015914 65 30 0,000 0,08805689 0,10740039 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,08805689 0,10734679 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,08805689 0,10729326 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,08805689 0,10723977 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,08805689 0,10718634 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,08805689 0,10713296 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,08805689 0,10707963 ! regulation of coagulation GO:0050818 52 30 0,000 0,08805689 0,10702636 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,09085583 0,11037335 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,09085583 0,11031849 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,09085583 0,11026369 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,09085583 0,11020894 ! cell junction assembly GO:0034329 85 31 0,000 0,09085583 0,11015425 ! regulation of innate immune response GO:0045088 57 31 0,000 0,09085583 0,11009961 ! ovulation cycle process GO:0022602 55 31 0,000 0,09085583 0,11004502 ! peptide transport GO:0015833 60 31 0,000 0,09085583 0,10999049 ! male gonad development GO:0008584 56 31 0,000 0,09085583 0,10993601 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,09085583 0,10988159 ! detection of light stimulus GO:0009583 44 31 0,000 0,09085583 0,10982722 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,09085583 0,1097729 ! natural killer cell activation GO:0030101 50 31 0,000 0,09085583 0,10971864 ! ensheathment of neurons GO:0007272 64 31 0,000 0,09085583 0,10966443 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,09085583 0,10961027 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,09085583 0,10955617 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,09085583 0,10950212 ! eye morphogenesis GO:0048592 65 31 0,000 0,09085583 0,10944813 ! response to heat GO:0009408 54 31 0,000 0,09085583 0,10939419 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,09085583 0,1093403 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,09364627 0,11264295 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,09364627 0,11258752 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,09364627 0,11253214 ! spindle organization GO:0007051 50 32 0,000 0,09364627 0,11247681 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,09364627 0,11242154 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,09364627 0,11236632 ! metanephros development GO:0001656 81 32 0,000 0,09364627 0,11231116 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,09364627 0,11225605 ! muscle cell development GO:0055001 52 32 0,000 0,09364627 0,112201 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,09364627 0,112146 ! ovulation cycle GO:0042698 57 32 0,000 0,09364627 0,11209105 ! peripheral nervous system development GO:0007422 68 32 0,000 0,09364627 0,11203616 ! BMP signaling pathway GO:0030509 71 32 0,000 0,09364627 0,11198132 ! hindbrain development GO:0030902 65 32 0,000 0,09364627 0,11192653 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,09364627 0,1118718 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,09364627 0,11181712 ! gene silencing GO:0016458 71 32 0,000 0,09364627 0,1117625 ! regulation of pH GO:0006885 56 33 0,000 0,09642822 0,11502643 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,09642822 0,1149703 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,09642822 0,11491421 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,09642822 0,11485818 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,09642822 0,11480221 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,09642822 0,11474629 ! response to ionizing radiation GO:0010212 74 33 0,000 0,09642822 0,11469043 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,09642822 0,11463462 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,09642822 0,11457886 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,09642822 0,11452316 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,09642822 0,11446751 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,09642822 0,11441192 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,09642822 0,11435638 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,09920171 0,11758844 ! glial cell differentiation GO:0010001 67 34 0,000 0,09920171 0,11753141 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,09920171 0,11747444 ! cholesterol transport GO:0030301 62 34 0,000 0,09920171 0,11741752 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,09920171 0,11736066 ! spliceosome assembly GO:0000245 75 34 0,000 0,09920171 0,11730386 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,09920171 0,11724711 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,09920171 0,11719041 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,09920171 0,11713377 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,09920171 0,11707718 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,10196676 0,12028237 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,10196676 0,12022432 ! negative regulation of secretion GO:0051048 68 35 0,000 0,10196676 0,12016632 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,10196676 0,12010839 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,10196676 0,1200505 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,10196676 0,11999267 ! membrane docking GO:0022406 69 35 0,000 0,10196676 0,1199349 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,10196676 0,11987719 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,10196676 0,11981952 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,10196676 0,11976192 ! ceramide metabolic process GO:0006672 72 35 0,000 0,10196676 0,11970437 ! telencephalon development GO:0021537 81 35 0,000 0,10196676 0,11964687 ! sterol transport GO:0015918 63 35 0,000 0,10196676 0,11958943 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,10196676 0,11953205 ! vesicle localization GO:0051648 70 35 0,000 0,10196676 0,11947472 ! regulation of muscle development GO:0048634 82 36 0,000 0,1047234 0,12264586 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,1047234 0,1225871 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,1047234 0,12252839 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,1047234 0,12246973 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,1047234 0,12241113 ! positive regulation of cell development GO:0010720 85 36 0,000 0,1047234 0,12235259 ! protein targeting to membrane GO:0006612 75 36 0,000 0,1047234 0,12229411 ! regulation of proteolysis GO:0030162 77 36 0,000 0,1047234 0,12223568 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,1047234 0,1221773 ! aerobic respiration GO:0009060 56 36 0,000 0,1047234 0,12211898 ! cytokine production GO:0001816 68 36 0,000 0,1047234 0,12206072 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,1047234 0,12200251 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,10747166 0,12514455 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,10747166 0,12508493 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,10747166 0,12502536 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,10747166 0,12496586 ! sister chromatid segregation GO:0000819 65 37 0,000 0,10747166 0,1249064 ! odontogenesis GO:0042476 74 37 0,000 0,10747166 0,12484701 ! actomyosin structure organization GO:0031032 68 37 0,000 0,10747166 0,12478767 ! cell junction organization GO:0034330 96 37 0,000 0,10747166 0,12472839 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,10747166 0,12466917 ! female gonad development GO:0008585 71 37 0,000 0,10747166 0,12461 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,10747166 0,12455088 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,10747166 0,12449183 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,11021156 0,12760514 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,11021156 0,12754469 ! meiosis I GO:0007127 74 38 0,000 0,11021156 0,1274843 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,11021156 0,12742396 ! organic anion transport GO:0015711 82 38 0,000 0,11021156 0,12736369 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,11021156 0,12730347 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,11021156 0,12724331 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,11021156 0,1271832 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,11021156 0,12712315 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,11021156 0,12706316 ! regulation of protein stability GO:0031647 77 38 0,000 0,11021156 0,12700322 ! spermatid development GO:0007286 69 38 0,000 0,11021156 0,12694335 ! glycogen metabolic process GO:0005977 63 38 0,000 0,11021156 0,12688352 ! pigment metabolic process GO:0042440 87 38 0,000 0,11021156 0,12682376 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,11021156 0,12676405 ! neural tube formation GO:0001841 79 38 0,000 0,11021156 0,12670439 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,11294312 0,12978365 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,11294312 0,12972264 ! negative regulation of binding GO:0051100 71 39 0,000 0,11294312 0,12966168 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,11294312 0,12960077 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,11294312 0,12953993 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,11294312 0,12947914 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,11294312 0,12941841 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,11294312 0,12935774 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,11294312 0,12929712 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,11294312 0,12923656 ! glucan metabolic process GO:0044042 64 39 0,000 0,11294312 0,12917605 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,11566638 0,13222881 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,11566638 0,13216696 ! learning GO:0007612 82 40 0,000 0,11566638 0,13210517 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,11566638 0,13204344 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,11566638 0,13198177 ! lipid homeostasis GO:0055088 75 40 0,000 0,11566638 0,13192015 ! mismatch repair GO:0006298 58 40 0,000 0,11566638 0,13185859 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,11566638 0,13179709 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,11566638 0,13173565 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,11566638 0,13167426 ! RNA export from nucleus GO:0006405 61 41 0,000 0,11838135 0,13470221 ! mRNA catabolic process GO:0006402 79 41 0,000 0,11838135 0,1346395 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,11838135 0,13457684 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,11838135 0,13451425 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,11838135 0,13445172 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,11838135 0,13438924 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,11838135 0,13432682 ! feeding behavior GO:0007631 69 41 0,000 0,11838135 0,13426446 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,11838135 0,13420215 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,11838135 0,13413991 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,11838135 0,13407772 ! spermatid differentiation GO:0048515 73 41 0,000 0,11838135 0,13401559 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,11838135 0,13395352 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,12108806 0,13695284 ! ear morphogenesis GO:0042471 64 42 0,000 0,12108806 0,13688947 ! organic ether metabolic process GO:0018904 59 42 0,000 0,12108806 0,13682615 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,12108806 0,13676289 ! T cell differentiation GO:0030217 93 42 0,000 0,12108806 0,13669969 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,12108806 0,13663655 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,12108806 0,13657347 ! regulation of protein secretion GO:0050708 77 42 0,000 0,12108806 0,13651045 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,12108806 0,13644748 ! cytokinesis GO:0000910 84 42 0,000 0,12108806 0,13638457 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,12108806 0,13632172 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,12378654 0,1392955 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,12378654 0,13923136 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,12378654 0,13916729 ! glucose transport GO:0015758 66 43 0,000 0,12378654 0,13910328 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,12378654 0,13903932 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,12378654 0,13897542 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,12378654 0,13891159 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,12378654 0,13884781 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,12378654 0,13878409 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,12378654 0,13872042 ! ion transmembrane transport GO:0034220 79 43 0,000 0,12378654 0,13865682 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,12647681 0,14160534 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,12647681 0,14154047 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,12647681 0,14147567 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,12647681 0,14141092 ! hexose transport GO:0008645 68 44 0,000 0,12647681 0,14134623 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,12647681 0,1412816 ! striated muscle contraction GO:0006941 85 44 0,000 0,12647681 0,14121703 ! phagocytosis GO:0006909 105 44 0,000 0,12647681 0,14115251 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,12647681 0,14108806 ! double-strand break repair GO:0006302 85 44 0,000 0,12647681 0,14102367 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,1291589 0,14394853 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,1291589 0,14388289 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,1291589 0,14381731 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,1291589 0,14375179 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,1291589 0,14368633 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,1291589 0,14362093 ! female gamete generation GO:0007292 71 45 0,000 0,1291589 0,14355559 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,1291589 0,14349031 ! polyol metabolic process GO:0019751 77 45 0,000 0,1291589 0,14342509 ! developmental growth GO:0048589 88 45 0,000 0,1291589 0,14335992 ! maintenance of location in cell GO:0051651 101 45 0,000 0,1291589 0,14329482 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,13183282 0,146195 ! glycolysis GO:0006096 71 46 0,000 0,13183282 0,14612867 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,13183282 0,1460624 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,13183282 0,14599619 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,13183282 0,14593003 ! pigmentation GO:0043473 103 46 0,000 0,13183282 0,14586394 ! neural tube development GO:0021915 91 47 0,000 0,13449861 0,14874609 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,13449861 0,14867878 ! response to insulin stimulus GO:0032868 98 47 0,000 0,13449861 0,14861154 ! positive regulation of defense response GO:0031349 88 48 0,000 0,13715629 0,15147958 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,13715629 0,15141113 ! mitochondrial transport GO:0006839 94 48 0,000 0,13715629 0,15134274 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,13715629 0,15127441 ! cellular component disassembly GO:0022411 89 48 0,000 0,13715629 0,15120615 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,13715629 0,15113794 ! endosome transport GO:0016197 127 48 0,000 0,13715629 0,1510698 ! male sex differentiation GO:0046661 93 48 0,000 0,13715629 0,15100172 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,13715629 0,1509337 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,13715629 0,15086575 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,13715629 0,15079785 ! methylation GO:0032259 97 48 0,000 0,13715629 0,15073002 ! response to calcium ion GO:0051592 94 49 0,000 0,13980589 0,15357274 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,13980589 0,15350372 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,13980589 0,15343476 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,13980589 0,15336586 ! JNK cascade GO:0007254 106 49 0,000 0,13980589 0,15329703 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,13980589 0,15322825 ! regulation of action potential GO:0001508 102 50 0,000 0,14244742 0,15605338 ! regulation of ion transport GO:0043269 86 50 0,000 0,14244742 0,15598343 ! endocrine system development GO:0035270 109 50 0,000 0,14244742 0,15591355 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,14244742 0,15584373 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,14244742 0,15577397 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,14244742 0,15570427 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,14244742 0,15563463 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,14508091 0,15844107 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,14508091 0,15837027 ! peptide metabolic process GO:0006518 80 51 0,000 0,14508091 0,15829954 ! response to temperature stimulus GO:0009266 84 51 0,000 0,14508091 0,15822887 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,14508091 0,15815826 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,14508091 0,15808772 ! Notch signaling pathway GO:0007219 111 52 0,000 0,14770639 0,16087682 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,14770639 0,16080513 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,14770639 0,1607335 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,14770639 0,16066194 ! excretion GO:0007588 87 52 0,000 0,14770639 0,16059044 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,14770639 0,160519 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,14770639 0,16044763 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,14770639 0,16037632 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,14770639 0,16030507 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,15032388 0,16307338 ! positive regulation of growth GO:0045927 96 53 0,000 0,15032388 0,163001 ! vesicle organization GO:0016050 127 53 0,000 0,15032388 0,16292868 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,15032388 0,16285643 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,15032388 0,16278424 ! synapse organization GO:0050808 102 53 0,000 0,15032388 0,16271212 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,15293341 0,16546338 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,15293341 0,16539014 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,15293341 0,16531696 ! membrane fusion GO:0006944 122 54 0,000 0,15293341 0,16524384 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,15293341 0,16517079 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,15293341 0,1650978 ! regulation of cell shape GO:0008360 142 54 0,000 0,15293341 0,16502488 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,15293341 0,16495202 ! RNA catabolic process GO:0006401 103 55 0,000 0,15553499 0,16768402 ! cell recognition GO:0008037 98 55 0,000 0,15553499 0,16761005 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,15553499 0,16753615 ! cell maturation GO:0048469 107 55 0,000 0,15553499 0,16746231 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,15553499 0,16738854 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,15812866 0,17010494 ! glucose catabolic process GO:0006007 88 56 0,000 0,15812866 0,17003007 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,15812866 0,16995527 ! regulation of DNA replication GO:0006275 105 56 0,000 0,15812866 0,16988053 ! RNA elongation GO:0006354 90 56 0,000 0,15812866 0,16980586 ! muscle fiber development GO:0048747 131 57 0,000 0,16071444 0,17250675 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,16071444 0,17243099 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,16329234 0,17511993 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,16329234 0,17504309 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,16329234 0,17496631 ! aging GO:0007568 112 58 0,000 0,16329234 0,17488961 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,16329234 0,17481297 ! maintenance of location GO:0051235 124 58 0,000 0,16329234 0,1747364 ! nuclear export GO:0051168 110 59 0,000 0,1658624 0,17740887 ! establishment of organelle localization GO:0051656 122 59 0,000 0,1658624 0,17733123 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,16842464 0,17999186 ! lipid modification GO:0030258 112 60 0,000 0,16842464 0,17991316 ! DNA catabolic process GO:0006308 94 60 0,000 0,16842464 0,17983453 ! regulation of endocytosis GO:0030100 104 60 0,000 0,16842464 0,17975596 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,16842464 0,17967747 ! kidney development GO:0001822 133 60 0,000 0,16842464 0,17959904 ! positive regulation of secretion GO:0051047 110 61 0,000 0,17097908 0,18224341 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,17097908 0,18216393 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,17097908 0,18208452 ! regulation of heart contraction GO:0008016 123 61 0,000 0,17097908 0,18200518 ! proton transport GO:0015992 117 61 0,000 0,17097908 0,18192591 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,17097908 0,18184671 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,17352574 0,18447493 ! tRNA processing GO:0008033 102 62 0,000 0,17352574 0,18439469 ! regulation of mitosis GO:0007088 112 63 0,000 0,17606466 0,18701128 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,17606466 0,18693001 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,17606466 0,18684881 ! hydrogen transport GO:0006818 121 64 0,000 0,17859584 0,18945273 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,17859584 0,1893705 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,17859584 0,18928835 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,18111932 0,19187966 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,18111932 0,19179649 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,18111932 0,19171339 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,18363512 0,19429216 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,18363512 0,19420805 ! gonad development GO:0008406 115 66 0,000 0,18363512 0,19412401 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,18614326 0,1966903 ! activation of MAPK activity GO:0000187 124 67 0,000 0,18614326 0,19660526 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,18614326 0,1965203 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,18614326 0,19643541 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,18614326 0,19635059 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,18614326 0,19626585 ! secondary metabolic process GO:0019748 125 67 0,000 0,18614326 0,19618118 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,18864376 0,19873079 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,18864376 0,19864513 ! hexose catabolic process GO:0019320 113 68 0,000 0,18864376 0,19855955 ! extracellular matrix organization GO:0030198 146 68 0,000 0,18864376 0,19847403 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,18864376 0,1983886 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,18864376 0,19830323 ! adaptive immune response GO:0002250 126 68 0,000 0,18864376 0,19821794 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,18864376 0,19813272 ! negative regulation of cell size GO:0045792 144 69 0,000 0,19113665 0,20066474 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,19113665 0,20057854 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,19113665 0,20049242 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,19113665 0,20040637 ! urogenital system development GO:0001655 149 69 0,000 0,19113665 0,2003204 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,19113665 0,2002345 ! developmental maturation GO:0021700 128 69 0,000 0,19113665 0,20014867 ! single fertilization GO:0007338 83 69 0,000 0,19113665 0,20006291 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,19362196 0,20257749 ! cell redox homeostasis GO:0045454 114 70 0,000 0,19362196 0,20249077 ! germ cell development GO:0007281 133 70 0,000 0,19362196 0,20240412 ! activation of immune response GO:0002253 120 70 0,000 0,19362196 0,20231755 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,19362196 0,20223105 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,19609969 0,20473143 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,19609969 0,20464398 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,19609969 0,2045566 ! appendage morphogenesis GO:0035107 150 72 0,000 0,19856988 0,20704491 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,19856988 0,20695658 ! actin filament organization GO:0007015 167 72 0,000 0,19856988 0,20686833 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,19856988 0,20678015 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,19856988 0,20669204 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,19856988 0,20660401 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,19856988 0,20651606 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,19856988 0,20642818 ! appendage development GO:0048736 151 73 0,000 0,20103256 0,20889942 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,20103256 0,2088106 ! regulation of immune effector process GO:0002697 156 73 0,000 0,20103256 0,20872186 ! acute inflammatory response GO:0002526 118 74 0,000 0,20348773 0,21118119 ! amino acid transport GO:0006865 148 74 0,000 0,20348773 0,21109152 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,20348773 0,21100192 ! organelle localization GO:0051640 155 74 0,000 0,20348773 0,2109124 ! reproductive structure development GO:0048608 131 75 0,000 0,20593543 0,21335888 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,20593543 0,21326844 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,20593543 0,21317807 ! axon guidance GO:0007411 162 75 0,000 0,20593543 0,21308778 ! rhythmic process GO:0048511 142 75 0,000 0,20593543 0,21299756 ! learning or memory GO:0007611 161 76 0,000 0,20837567 0,21543029 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,20837567 0,21533916 ! regulation of blood pressure GO:0008217 134 76 0,000 0,20837567 0,2152481 ! neurotransmitter transport GO:0006836 142 77 0,000 0,21080849 0,21766912 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,21080849 0,21757716 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,21080849 0,21748527 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,21080849 0,21739347 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,21080849 0,21730174 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,21080849 0,21721009 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,21323389 0,21961652 ! fertilization GO:0009566 99 78 0,000 0,21323389 0,21952398 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,21323389 0,21943151 ! blood coagulation GO:0007596 151 79 0,000 0,21565191 0,22182637 GO:0050817|coagulation, ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,21565191 0,221733 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,21565191 0,22163972 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,21806257 0,22402307 ! meiosis GO:0007126 143 81 0,000 0,22046588 0,22639687 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,22046588 0,22630175 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,22046588 0,2262067 ! meiotic cell cycle GO:0051321 144 82 0,000 0,22286188 0,22856909 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,22525058 0,23092202 ! exocytosis GO:0006887 153 83 0,000 0,22525058 0,23082515 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,22525058 0,23072837 ! response to metal ion GO:0010038 158 84 0,000 0,227632 0,23306999 ! T cell activation GO:0042110 189 84 0,000 0,227632 0,23297234 ! response to nutrient GO:0007584 135 84 0,000 0,227632 0,23287478 ! digestion GO:0007586 130 84 0,000 0,227632 0,23277731 ! regulation of ligase activity GO:0051340 147 84 0,000 0,227632 0,23267991 ! hemostasis GO:0007599 165 85 0,000 0,23000617 0,2350084 ! negative regulation of transport GO:0051051 164 85 0,000 0,23000617 0,23491015 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,23000617 0,23481199 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,23000617 0,2347139 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,23000617 0,2346159 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,23000617 0,23451798 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,23000617 0,23442014 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,23237311 0,23673374 ! regulation of lyase activity GO:0051339 169 86 0,000 0,23237311 0,23663506 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,23237311 0,23653647 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,23473285 0,23883896 ! mitochondrion organization GO:0007005 159 87 0,000 0,23473285 0,23873953 ! alcohol catabolic process GO:0046164 142 87 0,000 0,23473285 0,23864018 ! nucleosome assembly GO:0006334 126 87 0,000 0,23473285 0,23854091 ! cellular respiration GO:0045333 143 88 0,000 0,23708539 0,24083144 ! amine biosynthetic process GO:0009309 146 88 0,000 0,23708539 0,24073134 ! sensory perception of smell GO:0007608 117 88 0,000 0,23708539 0,24063133 ! chromatin assembly GO:0031497 128 88 0,000 0,23708539 0,2405314 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,23708539 0,24043155 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,23943077 0,24270928 ! tube morphogenesis GO:0035239 194 89 0,000 0,23943077 0,24260861 ! cellular defense response GO:0006968 123 89 0,000 0,23943077 0,24250803 ! response to inorganic substance GO:0010035 173 90 0,000 0,241769 0,24477483 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,241769 0,24467343 ! response to unfolded protein GO:0006986 139 90 0,000 0,241769 0,24457212 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,241769 0,24447089 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,24410011 0,24672593 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,24642412 0,24897193 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,24874105 0,25120892 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,24874105 0,25110511 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,24874105 0,2510014 ! vitamin metabolic process GO:0006766 153 93 0,000 0,24874105 0,25089776 ! female pregnancy GO:0007565 166 94 0,000 0,25105092 0,25312315 ! sterol metabolic process GO:0016125 166 94 0,000 0,25105092 0,25301873 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,25105092 0,25291439 ! regulation of membrane potential GO:0042391 179 94 0,000 0,25105092 0,25281014 ! regulation of defense response GO:0031347 171 95 0,000 0,25335375 0,25502399 ! nucleosome organization GO:0034728 143 95 0,000 0,25335375 0,25491895 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,25335375 0,254814 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,25335375 0,25470914 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,25335375 0,25460437 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,25335375 0,25449968 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,25335375 0,25439507 ! sex differentiation GO:0007548 171 96 0,000 0,25564957 0,25659486 ! response to protein stimulus GO:0051789 158 96 0,000 0,25564957 0,25648949 ! regulation of T cell activation GO:0050863 175 96 0,000 0,25564957 0,25638419 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,25793839 0,25857345 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,25793839 0,25846739 ! transcription initiation GO:0006352 171 97 0,000 0,25793839 0,25836141 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,26022024 0,26054018 ! mRNA transport GO:0051028 185 100 0,000 0,2647631 0,26498003 ! positive regulation of immune response GO:0050778 175 100 0,000 0,2647631 0,26487152 ! hormone metabolic process GO:0042445 171 100 0,000 0,2647631 0,2647631