pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1100-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 7,866E-08 1,922E-04 ! positive regulation of inflammatory response GO:0050729 41 21 3,000 1,767E-07 2,158E-04 ! positive regulation of locomotion GO:0040017 44 22 3,000 2,156E-07 1,755E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 45 23 3,000 2,605E-07 1,591E-04 ! nuclear migration GO:0007097 13 6 2,000 2,626E-07 1,283E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 2,626E-07 1,069E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 2,636E-07 9,199E-05 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 3,12E-07 9,527E-05 ! regulation of behavior GO:0050795 48 25 3,000 3,707E-07 1,006E-04 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 4,373E-07 1,068E-04 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 4,587E-07 1,019E-04 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 6,917E-07 1,408E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 4,000 6,917E-07 1,3E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 7,327E-07 1,279E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 7,327E-07 1,193E-04 ! negative regulation of kinase activity GO:0033673 145 70 4,000 7,435E-07 1,135E-04 ! negative regulation of transferase activity GO:0051348 155 74 4,000 9,822E-07 1,412E-04 ! induction of positive chemotaxis GO:0050930 17 9 2,000 1,097E-06 1,489E-04 ! macrophage differentiation GO:0030225 15 9 2,000 1,097E-06 1,411E-04 ! leukocyte chemotaxis GO:0030595 55 33 3,000 1,182E-06 1,444E-04 GO:0060326|cell chemotaxis, ! positive regulation of phosphorylation GO:0042327 149 81 4,000 1,542E-06 1,794E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 1,565E-06 1,738E-04 ! protein sumoylation GO:0016925 17 10 2,000 1,565E-06 1,662E-04 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 1,741E-06 1,772E-04 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of transport GO:0051051 164 85 4,000 1,959E-06 1,915E-04 ! chondrocyte differentiation GO:0002062 27 11 2,000 2,148E-06 2,018E-04 ! negative regulation of glucose import GO:0046325 18 11 2,000 2,148E-06 1,943E-04 GO:0010829|negative regulation of glucose transport, ! nucleus localization GO:0051647 22 11 2,000 2,148E-06 1,874E-04 ! regulation of positive chemotaxis GO:0050926 22 12 2,000 2,859E-06 2,408E-04 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 33 12 2,000 2,859E-06 2,328E-04 ! positive regulation of response to external stimulus GO:0032103 88 44 3,000 3,843E-06 3,029E-04 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 4,21E-06 3,214E-04 ! leukocyte migration GO:0050900 75 46 3,000 4,603E-06 3,408E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 4,714E-06 3,387E-04 ! positive regulation of defense response GO:0031349 88 48 3,000 5,468E-06 3,817E-04 ! regulation of inflammatory response GO:0050727 84 48 3,000 5,468E-06 3,711E-04 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 5,882E-06 3,884E-04 ! filopodium assembly GO:0046847 42 17 2,000 8,76E-06 5,632E-04 ! neutrophil chemotaxis GO:0030593 29 17 2,000 8,76E-06 5,487E-04 ! microspike assembly GO:0030035 46 18 2,000 1,049E-05 6,409E-04 ! regulation of glucose import GO:0046324 30 20 2,000 1,461E-05 8,705E-04 GO:0010827|regulation of glucose transport, ! inactivation of MAPK activity GO:0000188 45 22 2,000 1,967E-05 1,144E-03 ! positive regulation of B cell activation GO:0050871 42 22 2,000 1,967E-05 1,117E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 2,576E-05 1,43E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 2,922E-05 1,586E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 3,000 3,084E-05 1,638E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 3,703E-05 1,925E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 4,141E-05 2,107E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 4,611E-05 2,299E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 5,114E-05 2,499E-03 ! regulation of B cell activation GO:0050864 55 30 2,000 5,114E-05 2,45E-03 ! regulation of collagen biosynthetic process GO:0032965 7 5 1,000 5,625E-05 2,643E-03 ! response to protozoan GO:0001562 13 5 1,000 5,625E-05 2,593E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 5,625E-05 2,545E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 5,625E-05 2,499E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 5,625E-05 2,454E-03 ! decidualization GO:0046697 11 5 1,000 5,625E-05 2,411E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 5,625E-05 2,369E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 5,625E-05 2,329E-03 ! positive regulation of protein modification process GO:0031401 156 90 3,000 6,653E-05 2,709E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 7,486E-05 2,998E-03 ! regulation of defense response GO:0031347 171 95 3,000 8,214E-05 3,237E-03 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 8,425E-05 3,267E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 1,000 8,425E-05 3,216E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 8,425E-05 3,166E-03 ! regulation of collagen metabolic process GO:0010712 10 6 1,000 8,425E-05 3,118E-03 ! neutrophil homeostasis GO:0001780 11 6 1,000 8,425E-05 3,072E-03 ! salivary gland morphogenesis GO:0007435 14 6 1,000 8,425E-05 3,027E-03 ! organ or tissue specific immune response GO:0002251 8 6 1,000 8,425E-05 2,983E-03 ! maternal placenta development GO:0001893 12 6 1,000 8,425E-05 2,94E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 9,27E-05 3,19E-03 ! positive regulation of leukocyte proliferation GO:0070665 70 39 2,000 1,133E-04 3,846E-03 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,178E-04 3,941E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,178E-04 3,888E-03 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 1,000 1,178E-04 3,836E-03 ! defense response to Gram-negative bacterium GO:0050829 10 7 1,000 1,178E-04 3,786E-03 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 1,317E-04 4,18E-03 ! positive regulation of transcription factor activity GO:0051091 71 43 2,000 1,52E-04 4,761E-03 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,568E-04 4,848E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,568E-04 4,788E-03 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 1,000 1,568E-04 4,728E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,568E-04 4,671E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 1,000 1,568E-04 4,614E-03 GO:0002688|regulation of leukocyte chemotaxis, ! myeloid cell homeostasis GO:0002262 15 8 1,000 1,568E-04 4,56E-03 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 1,568E-04 4,506E-03 ! negative regulation of DNA replication initiation GO:0032297 10 8 1,000 1,568E-04 4,454E-03 GO:0000076|DNA replication checkpoint, ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,86E-04 5,223E-03 ! pigmentation GO:0043473 103 46 2,000 1,86E-04 5,164E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 2,013E-04 5,524E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 2,013E-04 5,463E-03 ! regulation of telomere maintenance GO:0032204 17 9 1,000 2,013E-04 5,403E-03 ! positive regulation of DNA binding GO:0043388 83 48 2,000 2,112E-04 5,608E-03 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 2,246E-04 5,899E-03 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 2,385E-04 6,199E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 2,512E-04 6,459E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 2,512E-04 6,392E-03 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 2,512E-04 6,326E-03 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 2,512E-04 6,261E-03 ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 2,512E-04 6,198E-03 ! induction of an organ GO:0001759 17 10 1,000 2,512E-04 6,136E-03 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 2,512E-04 6,076E-03 ! salivary gland development GO:0007431 28 10 1,000 2,512E-04 6,016E-03 ! positive regulation of acute inflammatory response GO:0002675 18 10 1,000 2,512E-04 5,958E-03 ! blastocyst formation GO:0001825 18 10 1,000 2,512E-04 5,9E-03 ! regulation of cell projection organization GO:0031344 135 51 2,000 2,53E-04 5,886E-03 ! positive regulation of binding GO:0051099 88 52 2,000 2,68E-04 6,177E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 2,836E-04 6,475E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 2,000 2,836E-04 6,415E-03 ! regulation of muscle contraction GO:0006937 94 54 2,000 2,998E-04 6,718E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 3,065E-04 6,807E-03 ! detection of mechanical stimulus GO:0050982 22 11 1,000 3,065E-04 6,746E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 3,065E-04 6,686E-03 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 3,065E-04 6,627E-03 ! DNA methylation GO:0006306 19 11 1,000 3,065E-04 6,569E-03 GO:0006305|DNA alkylation, ! apical protein localization GO:0045176 18 11 1,000 3,065E-04 6,511E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 3,065E-04 6,455E-03 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 1,000 3,065E-04 6,4E-03 ! response to UV GO:0009411 120 55 2,000 3,165E-04 6,553E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 3,672E-04 7,539E-03 ! entry into host cell GO:0030260 34 12 1,000 3,672E-04 7,477E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 3,672E-04 7,415E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,672E-04 7,354E-03 ! regulation of leukocyte migration GO:0002685 29 12 1,000 3,672E-04 7,294E-03 ! defense response to Gram-positive bacterium GO:0050830 14 12 1,000 3,672E-04 7,235E-03 ! developmental induction GO:0031128 22 12 1,000 3,672E-04 7,178E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 1,000 3,672E-04 7,121E-03 ! localization within membrane GO:0051668 26 12 1,000 3,672E-04 7,064E-03 ! positive regulation of cell migration GO:0030335 137 58 2,000 3,703E-04 7,068E-03 ! establishment of organelle localization GO:0051656 122 59 2,000 3,895E-04 7,376E-03 ! regulation of heart contraction GO:0008016 123 61 2,000 4,297E-04 8,075E-03 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 4,297E-04 8,014E-03 ! regulation of chemokine production GO:0032642 18 13 1,000 4,333E-04 8,02E-03 ! endocrine pancreas development GO:0031018 25 13 1,000 4,333E-04 7,96E-03 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 4,333E-04 7,9E-03 ! exocrine system development GO:0035272 34 13 1,000 4,333E-04 7,842E-03 ! asymmetric protein localization GO:0008105 24 13 1,000 4,333E-04 7,784E-03 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 4,333E-04 7,727E-03 ! gland morphogenesis GO:0022612 31 13 1,000 4,333E-04 7,671E-03 ! regulation of acute inflammatory response GO:0002673 24 13 1,000 4,333E-04 7,616E-03 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 1,000 4,333E-04 7,562E-03 ! regulation of protein complex assembly GO:0043254 132 63 2,000 4,725E-04 8,187E-03 ! cell-cell junction assembly GO:0007043 32 14 1,000 5,048E-04 8,684E-03 ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 5,048E-04 8,624E-03 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 1,000 5,048E-04 8,564E-03 ! regulation of T-helper 2 type immune response GO:0002828 25 14 1,000 5,048E-04 8,505E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 5,048E-04 8,447E-03 ! positive regulation of cell motion GO:0051272 157 65 2,000 5,18E-04 8,608E-03 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 5,417E-04 8,942E-03 ! myeloid cell differentiation GO:0030099 126 67 2,000 5,661E-04 9,282E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 5,815E-04 9,471E-03 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 1,000 5,815E-04 9,409E-03 ! cell projection assembly GO:0030031 138 68 2,000 5,912E-04 9,502E-03 ! lung development GO:0030324 165 69 2,000 6,17E-04 9,852E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 6,636E-04 0,01052687 ! DNA replication initiation GO:0006270 28 16 1,000 6,636E-04 0,01045896 ! regulation of T-helper cell differentiation GO:0045622 30 16 1,000 6,636E-04 0,01039191 ! cell cycle checkpoint GO:0000075 145 71 2,000 6,708E-04 0,01043776 ! respiratory tube development GO:0030323 171 72 2,000 6,987E-04 0,01080404 ! negative regulation of hormone secretion GO:0046888 26 17 1,000 7,509E-04 0,01153734 ! regulation of survival gene product expression GO:0045884 38 17 1,000 7,509E-04 0,01146523 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 1,000 7,509E-04 0,01139402 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 7,509E-04 0,01132368 ! respiratory system development GO:0060541 175 74 2,000 7,569E-04 0,01134382 ! organelle localization GO:0051640 155 74 2,000 7,569E-04 0,01127465 ! regulation of transcription factor activity GO:0051090 137 75 2,000 7,871E-04 0,01165319 GO:0090046|regulation of transcription regulator activity, ! positive regulation of anti-apoptosis GO:0045768 47 18 1,000 8,434E-04 0,01241287 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 8,434E-04 0,01233854 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 1,000 8,434E-04 0,0122651 ! regulation of immunoglobulin production GO:0002637 49 18 1,000 8,434E-04 0,01219253 ! defense response to virus GO:0051607 43 18 1,000 8,434E-04 0,01212081 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 8,822E-04 0,01260303 ! positive regulation of translation GO:0045727 31 19 1,000 9,412E-04 0,01336847 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 9,412E-04 0,0132912 ! mitotic chromosome condensation GO:0007076 37 19 1,000 9,412E-04 0,01321481 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 9,412E-04 0,0131393 ! cellular pigmentation GO:0033059 37 19 1,000 9,412E-04 0,01306465 ! peptide hormone secretion GO:0030072 32 19 1,000 9,412E-04 0,01299083 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,044E-03 0,01433089 ! protein amino acid acetylation GO:0006473 41 20 1,000 1,044E-03 0,01425083 ! response to alkaloid GO:0043279 38 20 1,000 1,044E-03 0,01417166 ! pancreas development GO:0031016 40 20 1,000 1,044E-03 0,01409336 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 1,044E-03 0,01401593 ! peptide secretion GO:0002790 38 20 1,000 1,044E-03 0,01393934 ! cell-cell junction organization GO:0045216 43 20 1,000 1,044E-03 0,01386358 ! hormone secretion GO:0046879 39 21 1,000 1,152E-03 0,01521642 ! lipid phosphorylation GO:0046834 43 21 1,000 1,152E-03 0,01513461 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 1,152E-03 0,01505368 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 1,152E-03 0,01497361 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 1,152E-03 0,01489438 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 1,152E-03 0,01481599 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 1,152E-03 0,01473842 ! positive regulation of cell activation GO:0050867 161 86 2,000 1,171E-03 0,01489345 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 2,000 1,21E-03 0,01531909 GO:0070201|regulation of establishment of protein localization, ! apoptotic nuclear changes GO:0030262 34 22 1,000 1,266E-03 0,01593679 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 1,000 1,266E-03 0,01585506 ! G1 phase GO:0051318 44 22 1,000 1,266E-03 0,01577417 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 1,266E-03 0,0156941 ! regulation of DNA binding GO:0051101 167 89 2,000 1,292E-03 0,01594367 ! regulation of anti-apoptosis GO:0045767 62 23 1,000 1,384E-03 0,01698962 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 1,384E-03 0,01690468 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 1,384E-03 0,01682057 ! regulation of interleukin-6 production GO:0032675 31 23 1,000 1,384E-03 0,0167373 ! DNA modification GO:0006304 36 23 1,000 1,384E-03 0,01665485 ! hormone transport GO:0009914 41 23 1,000 1,384E-03 0,01657321 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 1,384E-03 0,01649237 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 1,507E-03 0,01787656 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 1,507E-03 0,0177902 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 1,507E-03 0,01770467 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 1,507E-03 0,01761996 ! platelet activation GO:0030168 41 24 1,000 1,507E-03 0,01753606 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 1,636E-03 0,01894117 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,636E-03 0,01885183 ! vasculogenesis GO:0001570 49 25 1,000 1,636E-03 0,01876332 ! negative regulation of DNA replication GO:0008156 45 25 1,000 1,636E-03 0,01867564 ! chromosome condensation GO:0030261 48 25 1,000 1,636E-03 0,01858878 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 1,636E-03 0,01850272 ! interaction with host GO:0051701 66 25 1,000 1,636E-03 0,01841746 ! positive regulation of protein secretion GO:0050714 41 25 1,000 1,636E-03 0,01833297 ! leukocyte homeostasis GO:0001776 50 25 1,000 1,636E-03 0,01824926 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 1,655E-03 0,01837553 ! regulation of protein localization GO:0032880 188 97 2,000 1,655E-03 0,01829238 ! leukocyte differentiation GO:0002521 232 98 2,000 1,704E-03 0,01875282 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 1,77E-03 0,01938531 ! initiation of viral infection GO:0019059 60 26 1,000 1,77E-03 0,01929876 ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 1,77E-03 0,01921299 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 1,77E-03 0,01912798 ! blastocyst development GO:0001824 50 26 1,000 1,77E-03 0,01904371 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 1,908E-03 0,02044526 ! cellular response to oxidative stress GO:0034599 43 27 1,000 1,908E-03 0,02035598 ! regulation of chromosome organization GO:0033044 49 27 1,000 1,908E-03 0,02026747 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 2,052E-03 0,02169834 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 2,052E-03 0,02160481 ! protein amino acid acylation GO:0043543 59 28 1,000 2,052E-03 0,02151209 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 2,052E-03 0,02142015 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 2,2E-03 0,02287343 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 2,2E-03 0,02277651 ! autophagy GO:0006914 47 29 1,000 2,2E-03 0,0226804 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 2,2E-03 0,02258511 ! somitogenesis GO:0001756 52 29 1,000 2,2E-03 0,02249061 ! acute-phase response GO:0006953 50 30 1,000 2,354E-03 0,02395949 ! cell junction assembly GO:0034329 85 31 1,000 2,512E-03 0,02546609 ! peptide transport GO:0015833 60 31 1,000 2,512E-03 0,02536085 ! iron ion homeostasis GO:0055072 60 31 1,000 2,512E-03 0,02525649 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 2,512E-03 0,02515298 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 1,000 2,676E-03 0,02667894 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 2,676E-03 0,02657049 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 2,676E-03 0,02646292 ! response to mechanical stimulus GO:0009612 60 32 1,000 2,676E-03 0,02635622 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 2,676E-03 0,02625037 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 2,676E-03 0,02614537 ! negative regulation of protein transport GO:0051224 74 33 1,000 2,844E-03 0,02767835 ! cell fate specification GO:0001708 56 34 1,000 3,017E-03 0,02924619 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 3,017E-03 0,02913059 ! negative regulation of secretion GO:0051048 68 35 1,000 3,195E-03 0,0307268 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 3,195E-03 0,0306063 ! calcium-mediated signaling GO:0019722 67 35 1,000 3,195E-03 0,03048675 ! placenta development GO:0001890 53 35 1,000 3,195E-03 0,03036812 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 3,377E-03 0,03198028 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 3,377E-03 0,0318568 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 3,565E-03 0,03349574 ! sister chromatid segregation GO:0000819 65 37 1,000 3,565E-03 0,03336741 ! cell junction organization GO:0034330 96 37 1,000 3,565E-03 0,03324005 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 3,757E-03 0,03489923 ! DNA integrity checkpoint GO:0031570 82 38 1,000 3,757E-03 0,03476703 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 3,757E-03 0,03463584 ! nucleus organization GO:0006997 73 40 1,000 4,156E-03 0,0381667 ! regulation of hormone secretion GO:0046883 69 41 1,000 4,362E-03 0,03991187 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 4,573E-03 0,04168653 ! ear morphogenesis GO:0042471 64 42 1,000 4,573E-03 0,04153156 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 4,573E-03 0,04137774 ! regulation of T cell differentiation GO:0045580 78 42 1,000 4,573E-03 0,04122506 ! regulation of protein secretion GO:0050708 77 42 1,000 4,573E-03 0,0410735 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 4,789E-03 0,04285294 ! regulation of T cell proliferation GO:0042129 80 43 1,000 4,789E-03 0,04269654 ! segmentation GO:0035282 78 43 1,000 4,789E-03 0,04254128 ! response to reactive oxygen species GO:0000302 75 44 1,000 5,009E-03 0,04433695 ! biopolymer methylation GO:0043414 91 45 1,000 5,234E-03 0,04616018 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 5,234E-03 0,04599414 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 5,463E-03 0,0478384 ! cell growth GO:0016049 90 46 1,000 5,463E-03 0,04766755 ! positive regulation of protein transport GO:0051222 80 46 1,000 5,463E-03 0,04749792 ! response to insulin stimulus GO:0032868 98 47 1,000 5,697E-03 0,04935665 ! positive regulation of cell cycle GO:0045787 96 48 1,000 5,936E-03 0,05124134 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 5,936E-03 0,05106091 ! cellular component disassembly GO:0022411 89 48 1,000 5,936E-03 0,05088175 ! regulation of adaptive immune response GO:0002819 92 48 1,000 5,936E-03 0,05070384 ! methylation GO:0032259 97 48 1,000 5,936E-03 0,05052717 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 6,179E-03 0,05241329 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 6,179E-03 0,05223193 ! endocrine system development GO:0035270 109 50 1,000 6,426E-03 0,05413693 ! activation of caspase activity GO:0006919 95 50 1,000 6,426E-03 0,05395089 ! regulation of ossification GO:0030278 123 50 1,000 6,426E-03 0,05376613 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 6,426E-03 0,05358263 ! positive regulation of cytokine production GO:0001819 94 50 1,000 6,426E-03 0,05340037 ! viral infectious cycle GO:0019058 104 51 1,000 6,678E-03 0,05530607 ! peptide metabolic process GO:0006518 80 51 1,000 6,678E-03 0,05511922 ! detection of abiotic stimulus GO:0009582 80 51 1,000 6,678E-03 0,05493363 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 6,935E-03 0,05685138 ! histone modification GO:0016570 104 52 1,000 6,935E-03 0,05666124 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 7,196E-03 0,05859641 ! regulation of angiogenesis GO:0045765 125 54 1,000 7,461E-03 0,06055439 ! activation of phospholipase C activity GO:0007202 110 54 1,000 7,461E-03 0,06035388 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 7,461E-03 0,06015469 ! covalent chromatin modification GO:0016569 115 54 1,000 7,461E-03 0,05995681 ! regulation of cell shape GO:0008360 142 54 1,000 7,461E-03 0,05976023 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 7,73E-03 0,06171732 ! regulation of DNA replication GO:0006275 105 56 1,000 8,004E-03 0,06369627 ! regulation of bone remodeling GO:0046850 143 57 1,000 8,283E-03 0,06569671 ! positive regulation of caspase activity GO:0043280 108 57 1,000 8,283E-03 0,0654841 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 8,283E-03 0,06527286 ! regulation of intracellular transport GO:0032386 108 57 1,000 8,283E-03 0,06506298 ! regulation of tissue remodeling GO:0034103 146 58 1,000 8,565E-03 0,06706711 ! positive regulation of lipase activity GO:0060193 115 58 1,000 8,565E-03 0,06685284 ! lipid modification GO:0030258 112 60 1,000 9,143E-03 0,07113693 ! DNA catabolic process GO:0006308 94 60 1,000 9,143E-03 0,0709111 ! positive regulation of secretion GO:0051047 110 61 1,000 9,439E-03 0,07297024 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 9,439E-03 0,07274005 ! viral reproductive process GO:0022415 132 62 1,000 9,738E-03 0,07481291 ! regulation of homeostatic process GO:0032844 148 62 1,000 9,738E-03 0,07457839 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,01004203 0,07666461 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 0,01035 0,07876962 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,01035 0,078525 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,01066213 0,08064266 GO:0048609|reproductive process in a multicellular organism, ! ear development GO:0043583 114 66 1,000 0,01097839 0,08277843 ! regulation of cytokine biosynthetic process GO:0042035 108 66 1,000 0,01097839 0,08252372 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,01129877 0,08467145 ! chromosome segregation GO:0007059 127 67 1,000 0,01129877 0,08441252 ! detection of external stimulus GO:0009581 102 68 1,000 0,01162324 0,08657188 ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,01162324 0,08630874 ! viral reproduction GO:0016032 142 68 1,000 0,01162324 0,0860472 ! regulation of lipase activity GO:0060191 137 68 1,000 0,01162324 0,08578724 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01190063 0,08756997 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01190063 0,087307 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01190063 0,0870456 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01190063 0,08678576 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01190063 0,08652747 ! neuron fate determination GO:0048664 7 5 0,000 0,01190063 0,08627071 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01190063 0,08601547 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01190063 0,08576174 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01190063 0,0855095 ! polyol transport GO:0015791 12 5 0,000 0,01190063 0,08525874 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01190063 0,08500944 ! response to superoxide GO:0000303 10 5 0,000 0,01190063 0,0847616 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01190063 0,0845152 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01190063 0,08427023 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01190063 0,08402667 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01190063 0,08378452 ! female meiosis GO:0007143 10 5 0,000 0,01190063 0,08354376 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01190063 0,08330438 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01190063 0,08306637 ! hypothalamus development GO:0021854 9 5 0,000 0,01190063 0,08282971 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01190063 0,0825944 ! cobalt ion transport GO:0006824 11 5 0,000 0,01190063 0,08236042 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01190063 0,08212777 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01190063 0,08189642 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01190063 0,08166637 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01190063 0,08143762 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01190063 0,08121014 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01190063 0,08098393 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01190063 0,08075897 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01190063 0,08053526 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! transposition GO:0032196 9 5 0,000 0,01190063 0,08031279 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01190063 0,08009154 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01190063 0,07987151 ! negative chemotaxis GO:0050919 16 5 0,000 0,01190063 0,07965268 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01190063 0,07943505 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01190063 0,07921861 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01190063 0,07900334 ! behavioral response to pain GO:0048266 10 5 0,000 0,01190063 0,07878924 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01190063 0,0785763 ! Notch receptor processing GO:0007220 11 5 0,000 0,01190063 0,0783645 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01190063 0,07815384 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01190063 0,07794431 ! micturition GO:0060073 9 5 0,000 0,01190063 0,07773591 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01190063 0,07752861 ! copulation GO:0007620 9 5 0,000 0,01190063 0,07732242 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01190063 0,07711732 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01190063 0,07691331 ! bioluminescence GO:0008218 9 5 0,000 0,01190063 0,07671037 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01190063 0,0765085 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01190063 0,07630769 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01190063 0,07610793 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01190063 0,07590922 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01190063 0,07571153 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01190063 0,07551488 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01190063 0,07531925 ! grooming behavior GO:0007625 6 5 0,000 0,01190063 0,07512462 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01190063 0,074931 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01190063 0,07473838 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01190063 0,07454674 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01190063 0,07435609 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01190063 0,0741664 ! lymph vessel development GO:0001945 10 5 0,000 0,01190063 0,07397768 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01190063 0,07378992 ! endochondral ossification GO:0001958 17 5 0,000 0,01190063 0,07360311 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01190063 0,07341725 ! single strand break repair GO:0000012 8 5 0,000 0,01190063 0,07323232 ! parathyroid gland development GO:0060017 14 5 0,000 0,01190063 0,07304832 ! anagen GO:0042640 7 5 0,000 0,01190063 0,07286524 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01190063 0,07268307 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01190063 0,07250182 ! cytokine secretion GO:0050663 15 5 0,000 0,01190063 0,07232147 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01190063 0,07214201 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01190063 0,07196344 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01190063 0,07178575 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01190063 0,07160894 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01190063 0,071433 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01190063 0,07125792 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01190063 0,07108369 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01190063 0,07091032 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01190063 0,07073778 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01190063 0,07056609 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01190063 0,07039523 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01190063 0,07022519 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01190063 0,07005597 ! microvillus organization GO:0032528 8 5 0,000 0,01190063 0,06988757 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01190063 0,06971997 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01190063 0,06955318 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01190063 0,06938718 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01190063 0,06922197 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01190063 0,06905755 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01190063 0,06889391 ! polyol catabolic process GO:0046174 9 5 0,000 0,01190063 0,06873104 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01190063 0,06856894 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01190063 0,0684076 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01190063 0,06824702 ! muscle cell migration GO:0014812 8 5 0,000 0,01190063 0,06808719 ! mitochondrial fission GO:0000266 8 5 0,000 0,01190063 0,06792811 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01190063 0,06776977 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01190063 0,06761216 ! mRNA transcription GO:0009299 10 5 0,000 0,01190063 0,06745529 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01190063 0,06729914 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01190063 0,06714372 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01190063 0,06698901 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01190063 0,06683501 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01190063 0,06668172 ! monocyte activation GO:0042117 10 5 0,000 0,01190063 0,06652913 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01190063 0,06637724 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01190063 0,06622604 ! response to food GO:0032094 6 5 0,000 0,01190063 0,06607552 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01190063 0,06592569 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01190063 0,06577654 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01190063 0,06562806 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01190063 0,06548025 ! forebrain neuron development GO:0021884 13 5 0,000 0,01190063 0,0653331 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01190063 0,06518661 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01190063 0,06504078 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01190063 0,0648956 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01190063 0,06475107 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01190063 0,06460718 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01190063 0,06446392 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01190063 0,0643213 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01190063 0,06417931 ! lipid glycosylation GO:0030259 7 5 0,000 0,01190063 0,06403795 ! nucleobase transport GO:0015851 6 5 0,000 0,01190063 0,06389721 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01190063 0,06375708 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01190063 0,06361757 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01190063 0,06347867 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01190063 0,06334037 ! basic amino acid transport GO:0015802 12 5 0,000 0,01190063 0,06320267 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01190063 0,06306557 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01190063 0,06292907 ! actin nucleation GO:0045010 11 5 0,000 0,01190063 0,06279315 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01190063 0,06265782 ! depurination GO:0045007 5 5 0,000 0,01190063 0,06252307 ! depyrimidination GO:0045008 10 5 0,000 0,01190063 0,0623889 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01190063 0,06225531 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01190063 0,06212228 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01190063 0,06198983 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01190063 0,06185793 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01190063 0,0617266 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01190063 0,06159582 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01190063 0,0614656 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01190063 0,06133593 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01190063 0,0612068 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01190063 0,06107821 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01190063 0,06095017 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01190063 0,06082266 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01190063 0,06069568 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01190063 0,06056923 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01190063 0,0604433 ! response to arsenic GO:0046685 11 5 0,000 0,01190063 0,0603179 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01190063 0,06019302 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01190063 0,06006866 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01190063 0,0599448 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01190063 0,05982146 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01190063 0,05969862 ! response to mercury ion GO:0046689 8 5 0,000 0,01190063 0,05957629 ! response to cadmium ion GO:0046686 7 5 0,000 0,01190063 0,05945446 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01190063 0,05933312 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01190063 0,05921228 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01190063 0,05909193 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01190063 0,05897207 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01190063 0,05885269 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01190063 0,0587338 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01190063 0,05861538 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01190063 0,05849744 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01190063 0,05837998 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01190063 0,05826298 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01190063 0,05814646 ! embryonic cleavage GO:0040016 6 5 0,000 0,01190063 0,0580304 ! peroxisome fission GO:0016559 5 5 0,000 0,01190063 0,0579148 ! histone demethylation GO:0016577 13 5 0,000 0,01190063 0,05779966 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01190063 0,05768498 ! mitotic recombination GO:0006312 9 5 0,000 0,01190063 0,05757075 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01190063 0,05745698 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01190063 0,05734365 ! metaphase plate congression GO:0051310 7 5 0,000 0,01190063 0,05723077 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01190063 0,05711833 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01190063 0,05700633 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01190063 0,05689477 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01190063 0,05678365 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01190063 0,05667296 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01190063 0,0565627 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01190063 0,05645287 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01190063 0,05634347 ! B cell homeostasis GO:0001782 13 5 0,000 0,01190063 0,05623449 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01190063 0,05612593 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01190063 0,05601778 ! metaphase GO:0051323 11 5 0,000 0,01190063 0,05591006 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01190063 0,05580274 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01190063 0,05569584 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01190063 0,05558935 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01190063 0,05548326 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01190063 0,05537758 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01190063 0,0552723 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01190063 0,05516742 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01190063 0,05506293 ! response to redox state GO:0051775 6 5 0,000 0,01190063 0,05495885 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01190063 0,05485515 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01190063 0,05475184 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01190063 0,05464893 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01190063 0,0545464 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01190063 0,05444425 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01190063 0,05434248 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01190063 0,0542411 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01190063 0,05414009 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01190063 0,05403946 ! striatum development GO:0021756 14 5 0,000 0,01190063 0,0539392 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01190063 0,05383931 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01190063 0,0537398 ! glial cell migration GO:0008347 10 5 0,000 0,01190063 0,05364064 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01190063 0,05354186 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01190063 0,05344344 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01190063 0,05334538 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01190063 0,05324767 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01190063 0,05315033 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01190063 0,05305334 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01190063 0,0529567 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01190063 0,05286042 ! neuroprotection GO:0043526 8 5 0,000 0,01190063 0,05276448 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01190063 0,05266889 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01190063 0,05257365 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01190063 0,05247875 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01190063 0,0523842 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01190063 0,05228998 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01190063 0,0521961 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01190063 0,05210256 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01190063 0,05200935 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01190063 0,05191648 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01190063 0,05182394 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01190063 0,05173172 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01190063 0,05163984 ! spindle assembly GO:0051225 6 5 0,000 0,01190063 0,05154828 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01190063 0,05145704 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01190063 0,05136613 ! protein palmitoylation GO:0018345 12 5 0,000 0,01190063 0,05127554 ! drug metabolic process GO:0017144 7 5 0,000 0,01190063 0,05118526 ! stem cell division GO:0017145 11 5 0,000 0,01190063 0,05109531 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01190063 0,05100567 ! organ regeneration GO:0031100 7 5 0,000 0,01190063 0,05091634 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01190063 0,05082732 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01190063 0,05073862 ! negative regulation of cell size GO:0045792 144 69 1,000 0,01195178 0,05086796 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,01195178 0,05077949 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,01296164 0,05497446 ! humoral immune response GO:0006959 115 73 1,000 0,01330627 0,05633832 ! regulation of immune effector process GO:0002697 156 73 1,000 0,01330627 0,05624085 ! acute inflammatory response GO:0002526 118 74 1,000 0,01365486 0,05761455 ! regulation of caspase activity GO:0043281 136 74 1,000 0,01365486 0,05751522 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,0140074 0,0588986 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0142639 0,05987407 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0142639 0,05977137 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,0142639 0,05966903 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,0142639 0,05956703 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0142639 0,05946538 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,0142639 0,05936407 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,0142639 0,05926311 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0142639 0,0591625 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,0142639 0,05906222 ! response to oxygen radical GO:0000305 11 6 0,000 0,0142639 0,05896229 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,0142639 0,05886269 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,0142639 0,05876343 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,0142639 0,0586645 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,0142639 0,0585659 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0142639 0,05846764 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0142639 0,0583697 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,0142639 0,05827209 ! forebrain regionalization GO:0021871 9 6 0,000 0,0142639 0,05817481 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0142639 0,05807785 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0142639 0,05798122 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,0142639 0,0578849 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0142639 0,05778891 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,0142639 0,05769323 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,0142639 0,05759787 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0142639 0,05750282 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,0142639 0,05740809 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,0142639 0,05731367 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0142639 0,05721956 ! malate metabolic process GO:0006108 13 6 0,000 0,0142639 0,05712576 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,0142639 0,05703226 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,0142639 0,05693907 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,0142639 0,05684618 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,0142639 0,0567536 ! protein refolding GO:0042026 15 6 0,000 0,0142639 0,05666132 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0142639 0,05656934 ! opsonization GO:0008228 8 6 0,000 0,0142639 0,05647765 ! mating behavior GO:0007617 7 6 0,000 0,0142639 0,05638626 ! erythrocyte maturation GO:0043249 8 6 0,000 0,0142639 0,05629517 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,0142639 0,05620437 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,0142639 0,05611387 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,0142639 0,05602365 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,0142639 0,05593373 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0142639 0,05584409 ! response to interferon-gamma GO:0034341 16 6 0,000 0,0142639 0,05575474 ! toxin metabolic process GO:0009404 11 6 0,000 0,0142639 0,05566567 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0142639 0,05557689 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,0142639 0,05548839 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,0142639 0,05540018 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,0142639 0,05531224 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,0142639 0,05522458 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0142639 0,0551372 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,0142639 0,0550501 ! thymic T cell selection GO:0045061 16 6 0,000 0,0142639 0,05496327 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,0142639 0,05487671 ! protein lipoylation GO:0009249 10 6 0,000 0,0142639 0,05479043 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,0142639 0,05470441 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,0142639 0,05461867 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0142639 0,05453319 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,0142639 0,05444799 ! glutamate catabolic process GO:0006538 12 6 0,000 0,0142639 0,05436304 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,0142639 0,05427837 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0142639 0,05419395 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! response to pH GO:0009268 10 6 0,000 0,0142639 0,0541098 ! hyperosmotic response GO:0006972 10 6 0,000 0,0142639 0,05402591 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,0142639 0,05394228 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,0142639 0,0538589 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,0142639 0,05377579 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0142639 0,05369293 ! urea metabolic process GO:0019627 7 6 0,000 0,0142639 0,05361033 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0142639 0,05352797 ! neutrophil activation GO:0042119 7 6 0,000 0,0142639 0,05344588 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0142639 0,05336403 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,0142639 0,05328243 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0142639 0,05320109 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,0142639 0,05311999 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,0142639 0,05303913 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0142639 0,05295853 ! neuron apoptosis GO:0051402 15 6 0,000 0,0142639 0,05287817 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0142639 0,05279805 ! T cell mediated immunity GO:0002456 17 6 0,000 0,0142639 0,05271817 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0142639 0,05263854 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,0142639 0,05255914 ! carnitine transport GO:0015879 10 6 0,000 0,0142639 0,05247999 GO:0015838|betaine transport, ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,0142639 0,05240107 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,0142639 0,05232239 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,0142639 0,05224395 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,0142639 0,05216574 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0142639 0,05208776 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,0142639 0,05201002 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,0142639 0,05193251 ! establishment of spindle localization GO:0051293 16 6 0,000 0,0142639 0,05185523 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,0142639 0,05177817 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0142639 0,05170135 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,0142639 0,05162476 ! response to UV-C GO:0010225 14 6 0,000 0,0142639 0,05154839 ! astrocyte development GO:0014002 16 6 0,000 0,0142639 0,05147225 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,0142639 0,05139633 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0142639 0,05132064 ! interaction with symbiont GO:0051702 14 6 0,000 0,0142639 0,05124516 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0142639 0,05116991 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,0142639 0,05109488 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,0142639 0,05102008 ! response to copper ion GO:0046688 10 6 0,000 0,0142639 0,05094548 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,0142639 0,05087111 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,0142639 0,05079696 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0142639 0,05072302 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,0142639 0,05064929 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0142639 0,05057578 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,0142639 0,05050248 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0142639 0,05042939 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,0142639 0,05035652 ! hair follicle maturation GO:0048820 8 6 0,000 0,0142639 0,05028385 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0142639 0,0502114 ! Schwann cell development GO:0014044 15 6 0,000 0,0142639 0,05013915 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,0142639 0,05006711 ! response to pheromone GO:0019236 6 6 0,000 0,0142639 0,04999528 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,0142639 0,04992366 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,0142639 0,04985223 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,0142639 0,04978102 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,0142639 0,04971 ! subpallium development GO:0021544 15 6 0,000 0,0142639 0,04963919 ! neural tube patterning GO:0021532 8 6 0,000 0,0142639 0,04956858 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,0142639 0,04949817 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,0142639 0,04942796 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0142639 0,04935795 ! G2 phase GO:0051319 16 6 0,000 0,0142639 0,04928813 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,0142639 0,04921852 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,0142639 0,0491491 ! oxygen homeostasis GO:0032364 10 6 0,000 0,0142639 0,04907988 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0142639 0,04901085 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,0142639 0,04894201 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0142639 0,04887337 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,0142639 0,04880492 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0142639 0,04873666 ! receptor internalization GO:0031623 11 6 0,000 0,0142639 0,04866859 ! plasminogen activation GO:0031639 9 6 0,000 0,0142639 0,04860071 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0142639 0,04853302 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 16 6 0,000 0,0142639 0,04846552 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,0142639 0,04839821 ! protein destabilization GO:0031648 9 6 0,000 0,0142639 0,04833108 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,0142639 0,04826414 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0142639 0,04819739 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,0142639 0,04813082 ! regulation of viral transcription GO:0046782 11 6 0,000 0,0142639 0,04806443 ! progesterone metabolic process GO:0042448 12 6 0,000 0,0142639 0,04799822 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,0142639 0,0479322 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,0142639 0,04786636 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,0142639 0,0478007 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0142639 0,04773522 ! determination of adult lifespan GO:0008340 17 6 0,000 0,0142639 0,04766992 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,0142639 0,0476048 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0142639 0,04753985 ! neural plate development GO:0001840 9 6 0,000 0,0142639 0,04747508 ! catecholamine transport GO:0051937 9 6 0,000 0,0142639 0,04741049 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,0142639 0,04734608 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0142639 0,04728183 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,0142639 0,04721777 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,0142639 0,04715387 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0142639 0,04709015 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,0142639 0,0470266 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,0142639 0,04696322 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,0142639 0,04690002 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,0142639 0,04683698 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,0142639 0,04677411 GO:0055081|anion homeostasis, ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01472425 0,04821897 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,01472425 0,04815442 ! blood coagulation GO:0007596 151 79 1,000 0,01545665 0,05048208 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,01545665 0,05041468 ! response to hypoxia GO:0001666 178 81 1,000 0,01620444 0,05278325 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,01658405 0,05394785 ! tRNA transcription GO:0009304 17 7 0,000 0,01662159 0,05399807 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01662159 0,05392636 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01662159 0,05385484 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01662159 0,05378351 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01662159 0,05371236 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01662159 0,05364141 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01662159 0,05357064 ! sleep GO:0030431 16 7 0,000 0,01662159 0,05350006 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01662159 0,05342967 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01662159 0,05335946 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01662159 0,05328943 ! prostate gland development GO:0030850 14 7 0,000 0,01662159 0,05321959 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01662159 0,05314993 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01662159 0,05308045 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01662159 0,05301116 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01662159 0,05294204 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01662159 0,05287311 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01662159 0,05280435 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01662159 0,05273577 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01662159 0,05266738 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01662159 0,05259915 ! glycolipid transport GO:0046836 11 7 0,000 0,01662159 0,05253111 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01662159 0,05246324 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01662159 0,05239554 ! neuron adhesion GO:0007158 14 7 0,000 0,01662159 0,05232802 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01662159 0,05226068 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01662159 0,0521935 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01662159 0,0521265 ! mRNA stabilization GO:0048255 18 7 0,000 0,01662159 0,05205968 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01662159 0,05199302 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01662159 0,05192653 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01662159 0,05186021 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01662159 0,05179406 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01662159 0,05172808 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01662159 0,05166227 ! lipoprotein transport GO:0042953 14 7 0,000 0,01662159 0,05159663 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01662159 0,05153115 ! rhythmic behavior GO:0007622 17 7 0,000 0,01662159 0,05146584 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01662159 0,05140069 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01662159 0,05133571 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01662159 0,05127089 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01662159 0,05120624 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01662159 0,05114175 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01662159 0,05107742 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01662159 0,05101325 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01662159 0,05094924 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01662159 0,0508854 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01662159 0,05082171 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01662159 0,05075818 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01662159 0,05069481 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01662159 0,0506316 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01662159 0,05056855 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01662159 0,05050566 ! spinal cord patterning GO:0021511 14 7 0,000 0,01662159 0,05044292 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01662159 0,05038033 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01662159 0,0503179 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01662159 0,05025563 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01662159 0,05019351 ! adrenal gland development GO:0030325 17 7 0,000 0,01662159 0,05013154 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01662159 0,05006972 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01662159 0,05000806 ! ovulation GO:0030728 10 7 0,000 0,01662159 0,04994655 ! adenohypophysis development GO:0021984 11 7 0,000 0,01662159 0,04988519 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01662159 0,04982398 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01662159 0,04976292 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01662159 0,04970202 ! microtubule nucleation GO:0007020 21 7 0,000 0,01662159 0,04964126 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01662159 0,04958064 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01662159 0,04952018 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01662159 0,04945986 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01662159 0,04939969 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01662159 0,04933967 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01662159 0,04927979 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01662159 0,04922006 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01662159 0,04916047 ! galactose metabolic process GO:0006012 13 7 0,000 0,01662159 0,04910102 ! vesicle fusion GO:0006906 20 7 0,000 0,01662159 0,04904172 ! response to dietary excess GO:0002021 8 7 0,000 0,01662159 0,04898257 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01662159 0,04892355 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01662159 0,04886468 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01662159 0,04880595 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01662159 0,04874735 ! organ growth GO:0035265 15 7 0,000 0,01662159 0,0486889 ! nucleoside transport GO:0015858 11 7 0,000 0,01662159 0,04863059 ! nucleoside salvage GO:0043174 11 7 0,000 0,01662159 0,04857242 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01662159 0,04851439 ! male sex determination GO:0030238 15 7 0,000 0,01662159 0,0484565 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01662159 0,04839874 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01662159 0,04834113 ! parturition GO:0007567 16 7 0,000 0,01662159 0,04828365 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01662159 0,0482263 ! rRNA modification GO:0000154 14 7 0,000 0,01662159 0,04816909 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01662159 0,04811202 ! spindle checkpoint GO:0031577 16 7 0,000 0,01662159 0,04805508 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01662159 0,04799828 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01662159 0,04794161 ! monocyte differentiation GO:0030224 16 7 0,000 0,01662159 0,04788508 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01662159 0,04782868 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01662159 0,04777241 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01662159 0,04771627 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01662159 0,04766027 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01662159 0,04760439 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01662159 0,04754865 ! fibrinolysis GO:0042730 11 7 0,000 0,01662159 0,04749304 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01662159 0,04743755 ! eating behavior GO:0042755 8 7 0,000 0,01662159 0,0473822 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01662159 0,04732698 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01662159 0,04727188 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01662159 0,04721691 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01662159 0,04716208 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01662159 0,04710736 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01662159 0,04705278 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01662159 0,04699832 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01662159 0,04694398 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01662159 0,04688978 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01662159 0,04683569 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01662159 0,04678174 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01662159 0,0467279 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01662159 0,04667419 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01662159 0,0466206 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01662159 0,04656714 ! histone ubiquitination GO:0016574 9 7 0,000 0,01662159 0,0465138 ! regulation of meiosis GO:0040020 12 7 0,000 0,01662159 0,04646058 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01662159 0,04640748 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01662159 0,04635451 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01662159 0,04630165 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01662159 0,04624891 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01662159 0,0461963 ! transcription termination GO:0006353 14 7 0,000 0,01662159 0,0461438 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01662159 0,04609143 ! anaphase GO:0051322 18 7 0,000 0,01662159 0,04603917 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01662159 0,04598703 ! axonal fasciculation GO:0007413 19 7 0,000 0,01662159 0,04593501 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01662159 0,0458831 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01662159 0,04583132 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01662159 0,04577965 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01662159 0,04572809 ! diuresis GO:0030146 12 7 0,000 0,01662159 0,04567666 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01662159 0,04562533 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01662159 0,04557413 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01662159 0,04552303 ! antibiotic transport GO:0042891 9 7 0,000 0,01662159 0,04547206 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01662159 0,04542119 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01662159 0,04537044 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01662159 0,04531981 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01662159 0,04526928 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01662159 0,04521887 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01662159 0,04516857 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01662159 0,04511839 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01662159 0,04506831 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01662159 0,04501834 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01662159 0,04496849 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01662159 0,04491875 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01662159 0,04486911 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01662159 0,04481959 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01662159 0,04477017 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01662159 0,04472087 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01662159 0,04467167 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01662159 0,04462258 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01662159 0,0445736 ! muscle adaptation GO:0043500 13 7 0,000 0,01662159 0,04452472 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01662159 0,04447595 ! retina homeostasis GO:0001895 12 7 0,000 0,01662159 0,04442729 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01662159 0,04437874 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01662159 0,04433029 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01662159 0,04428195 ! response to drug GO:0042493 149 83 1,000 0,01696745 0,04515412 ! response to oxygen levels GO:0070482 183 83 1,000 0,01696745 0,04510499 ! hemostasis GO:0007599 165 85 1,000 0,01774554 0,04712211 ! negative regulation of growth GO:0045926 168 85 1,000 0,01774554 0,04707095 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,01774554 0,0470199 ! mitochondrion organization GO:0007005 159 87 1,000 0,01853853 0,04906786 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,01894057 0,05007772 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01897371 0,0501111 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01897371 0,05005698 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01897371 0,05000299 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01897371 0,0499491 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01897371 0,04989534 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01897371 0,04984169 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01897371 0,04978815 ! male meiosis GO:0007140 9 8 0,000 0,01897371 0,04973473 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01897371 0,04968142 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01897371 0,04962823 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01897371 0,04957515 ! meiotic prophase I GO:0007128 14 8 0,000 0,01897371 0,04952219 ! response to zinc ion GO:0010043 12 8 0,000 0,01897371 0,04946934 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01897371 0,0494166 ! oligopeptide transport GO:0006857 16 8 0,000 0,01897371 0,04936397 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01897371 0,04931145 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01897371 0,04925905 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01897371 0,04920676 ! signal peptide processing GO:0006465 12 8 0,000 0,01897371 0,04915458 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01897371 0,04910251 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01897371 0,04905055 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01897371 0,0489987 ! succinate metabolic process GO:0006105 17 8 0,000 0,01897371 0,04894696 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01897371 0,04889532 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01897371 0,0488438 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01897371 0,04879239 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01897371 0,04874108 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01897371 0,04868988 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01897371 0,04863879 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01897371 0,04858781 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01897371 0,04853693 ! reflex GO:0060004 17 8 0,000 0,01897371 0,04848616 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01897371 0,04843549 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01897371 0,04838493 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01897371 0,04833448 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01897371 0,04828413 ! pigment granule organization GO:0048753 17 8 0,000 0,01897371 0,04823389 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01897371 0,04818375 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01897371 0,04813371 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01897371 0,04808378 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01897371 0,04803396 ! histidine catabolic process GO:0006548 10 8 0,000 0,01897371 0,04798423 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01897371 0,04793461 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01897371 0,04788509 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01897371 0,04783567 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01897371 0,04778636 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01897371 0,04773714 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01897371 0,04768803 ! melanin metabolic process GO:0006582 17 8 0,000 0,01897371 0,04763902 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01897371 0,04759011 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01897371 0,0475413 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01897371 0,04749259 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01897371 0,04744398 ! macrophage activation GO:0042116 13 8 0,000 0,01897371 0,04739547 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01897371 0,04734706 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01897371 0,04729874 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01897371 0,04725053 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01897371 0,04720241 ! purine salvage GO:0043101 12 8 0,000 0,01897371 0,04715439 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01897371 0,04710647 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01897371 0,04705865 ! osteoblast development GO:0002076 17 8 0,000 0,01897371 0,04701092 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01897371 0,04696329 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01897371 0,04691576 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01897371 0,04686832 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01897371 0,04682098 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01897371 0,04677373 ! response to UV-B GO:0010224 17 8 0,000 0,01897371 0,04672658 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01897371 0,04667952 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01897371 0,04663256 ! intermediate filament organization GO:0045109 12 8 0,000 0,01897371 0,0465857 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01897371 0,04653892 ! cellular extravasation GO:0045123 13 8 0,000 0,01897371 0,04649224 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01897371 0,04644566 ! response to antibiotic GO:0046677 11 8 0,000 0,01897371 0,04639917 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01897371 0,04635277 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01897371 0,04630646 ! DNA topological change GO:0006265 12 8 0,000 0,01897371 0,04626025 ! response to tropane GO:0014073 15 8 0,000 0,01897371 0,04621412 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01897371 0,04616809 ! melanosome transport GO:0032402 13 8 0,000 0,01897371 0,04612216 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01897371 0,04607631 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01897371 0,04603055 ! mast cell activation GO:0045576 14 8 0,000 0,01897371 0,04598489 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01897371 0,04593931 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01897371 0,04589383 ! gas homeostasis GO:0033483 14 8 0,000 0,01897371 0,04584843 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01897371 0,04580313 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01897371 0,04575791 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01897371 0,04571279 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01897371 0,04566775 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01897371 0,0456228 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01897371 0,04557794 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01897371 0,04553317 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01897371 0,04548849 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01897371 0,04544389 ! response to tumor cell GO:0002347 16 8 0,000 0,01897371 0,04539938 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01897371 0,04535496 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01897371 0,04531062 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01897371 0,04526637 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01897371 0,04522221 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01897371 0,04517814 ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01897371 0,04513415 ! hormone catabolic process GO:0042447 17 8 0,000 0,01897371 0,04509024 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01897371 0,04504642 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01897371 0,04500269 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01897371 0,04495904 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01897371 0,04491547 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01897371 0,04487199 GO:0010828|positive regulation of glucose transport, ! adult feeding behavior GO:0008343 10 8 0,000 0,01897371 0,0448286 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01897371 0,04478528 ! ATP catabolic process GO:0006200 11 8 0,000 0,01897371 0,04474205 ! blastocyst growth GO:0001832 19 8 0,000 0,01897371 0,04469891 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01897371 0,04465585 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01897371 0,04461287 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01897371 0,04456997 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01897371 0,04452715 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01897371 0,04448442 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01897371 0,04444177 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01897371 0,0443992 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01897371 0,04435672 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01897371 0,04431431 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01897371 0,04427198 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01897371 0,04422974 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01897371 0,04418758 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01897371 0,04414549 ! protein prenylation GO:0018342 21 8 0,000 0,01897371 0,04410349 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01897371 0,04406157 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01897371 0,04401972 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01897371 0,04397796 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01897371 0,04393627 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,01975564 0,04570363 ! ossification GO:0001503 205 91 1,000 0,02016863 0,04661492 ! gland development GO:0048732 220 91 1,000 0,02016863 0,04657086 ! defense response to bacterium GO:0042742 112 91 1,000 0,02016863 0,04652688 ! bone development GO:0060348 206 92 1,000 0,02058523 0,04744313 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,02100542 0,04836593 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,02100542 0,04832039 ! axon extension GO:0048675 16 9 0,000 0,02132026 0,0489985 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02132026 0,04895245 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02132026 0,04890648 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02132026 0,04886061 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02132026 0,04881481 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02132026 0,04876911 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02132026 0,04872348 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02132026 0,04867795 ! reproductive behavior GO:0019098 22 9 0,000 0,02132026 0,0486325 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02132026 0,04858713 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02132026 0,04854185 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02132026 0,04849665 ! UTP metabolic process GO:0046051 10 9 0,000 0,02132026 0,04845154 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02132026 0,04840651 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02132026 0,04836156 ! artery development GO:0060840 25 9 0,000 0,02132026 0,0483167 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02132026 0,04827192 ! regulation of glycolysis GO:0006110 20 9 0,000 0,02132026 0,04822723 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02132026 0,04818261 ! equilibrioception GO:0050957 20 9 0,000 0,02132026 0,04813808 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02132026 0,04809363 ! chemosensory behavior GO:0007635 21 9 0,000 0,02132026 0,04804927 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02132026 0,04800498 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02132026 0,04796078 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02132026 0,04791666 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02132026 0,04787261 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02132026 0,04782865 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02132026 0,04778478 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02132026 0,04774098 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02132026 0,04769726 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02132026 0,04765362 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02132026 0,04761006 ! protein targeting to ER GO:0045047 25 9 0,000 0,02132026 0,04756658 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02132026 0,04752318 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02132026 0,04747986 ! T cell selection GO:0045058 27 9 0,000 0,02132026 0,04743662 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02132026 0,04739345 ! glycine catabolic process GO:0006546 15 9 0,000 0,02132026 0,04735037 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02132026 0,04730736 ! endosome organization GO:0007032 20 9 0,000 0,02132026 0,04726443 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02132026 0,04722158 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02132026 0,04717881 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02132026 0,04713611 ! mannose metabolic process GO:0006013 13 9 0,000 0,02132026 0,04709349 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02132026 0,04705095 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02132026 0,04700849 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02132026 0,0469661 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02132026 0,04692379 ! receptor clustering GO:0043113 20 9 0,000 0,02132026 0,04688155 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02132026 0,04683939 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02132026 0,04679731 ! retinol metabolic process GO:0042572 20 9 0,000 0,02132026 0,0467553 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02132026 0,04671337 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02132026 0,04667151 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02132026 0,04662973 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02132026 0,04658802 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02132026 0,04654639 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02132026 0,04650483 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02132026 0,04646334 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02132026 0,04642193 ! response to amine stimulus GO:0014075 13 9 0,000 0,02132026 0,04638059 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02132026 0,04633933 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02132026 0,04629814 ! erythrocyte development GO:0048821 17 9 0,000 0,02132026 0,04625702 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02132026 0,04621598 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02132026 0,046175 ! renal water homeostasis GO:0003091 15 9 0,000 0,02132026 0,04613411 ! postreplication repair GO:0006301 25 9 0,000 0,02132026 0,04609328 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02132026 0,04605252 ! icosanoid secretion GO:0032309 15 9 0,000 0,02132026 0,04601184 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02132026 0,04597123 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02132026 0,04593069 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02132026 0,04589022 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02132026 0,04584983 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02132026 0,0458095 ! sterol catabolic process GO:0016127 14 9 0,000 0,02132026 0,04576925 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02132026 0,04572907 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02132026 0,04568895 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02132026 0,04564891 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02132026 0,04560894 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02132026 0,04556903 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02132026 0,0455292 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02132026 0,04548944 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02132026 0,04544974 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02132026 0,04541012 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02132026 0,04537056 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02132026 0,04533107 ! purine base metabolic process GO:0006144 25 9 0,000 0,02132026 0,04529166 ! pigment granule transport GO:0051904 17 9 0,000 0,02132026 0,04525231 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02132026 0,04521303 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02132026 0,04517381 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02132026 0,04513467 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02132026 0,04509559 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02132026 0,04505658 ! mitochondrion localization GO:0051646 18 9 0,000 0,02132026 0,04501764 ! female pregnancy GO:0007565 166 94 1,000 0,02142919 0,04520856 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,02185651 0,04607028 ! regulation of T cell activation GO:0050863 175 96 1,000 0,02228736 0,04693796 ! transcription initiation GO:0006352 171 97 1,000 0,02272174 0,04781154 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02366127 0,04974569 ! regulation of developmental growth GO:0048638 16 10 0,000 0,02366127 0,04970292 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02366127 0,04966022 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02366127 0,04961759 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02366127 0,04957504 ! associative learning GO:0008306 21 10 0,000 0,02366127 0,04953255 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02366127 0,04949015 ! phosphate transport GO:0006817 24 10 0,000 0,02366127 0,04944781 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02366127 0,04940555 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02366127 0,04936336 ! CTP metabolic process GO:0046036 11 10 0,000 0,02366127 0,04932124 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02366127 0,04927919 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02366127 0,04923722 ! GTP metabolic process GO:0046039 11 10 0,000 0,02366127 0,04919531 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02366127 0,04915348 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02366127 0,04911172 ! social behavior GO:0035176 29 10 0,000 0,02366127 0,04907003 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02366127 0,04902841 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02366127 0,04898686 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02366127 0,04894538 ! androgen metabolic process GO:0008209 17 10 0,000 0,02366127 0,04890397 ! phospholipid efflux GO:0033700 19 10 0,000 0,02366127 0,04886263 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02366127 0,04882136 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02366127 0,04878016 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02366127 0,04873903 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02366127 0,04869797 ! lung alveolus development GO:0048286 26 10 0,000 0,02366127 0,04865698 ! pathogenesis GO:0009405 17 10 0,000 0,02366127 0,04861606 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02366127 0,0485752 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02366127 0,04853442 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02366127 0,0484937 ! endoderm development GO:0007492 18 10 0,000 0,02366127 0,04845305 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02366127 0,04841247 ! arginine catabolic process GO:0006527 17 10 0,000 0,02366127 0,04837196 ! proline metabolic process GO:0006560 13 10 0,000 0,02366127 0,04833151 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02366127 0,04829114 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02366127 0,04825083 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02366127 0,04821059 ! V(D)J recombination GO:0033151 34 10 0,000 0,02366127 0,04817041 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02366127 0,0481303 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02366127 0,04809026 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02366127 0,04805028 ! B cell proliferation GO:0042100 19 10 0,000 0,02366127 0,04801038 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02366127 0,04797053 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02366127 0,04793076 ! multicellular organism growth GO:0035264 19 10 0,000 0,02366127 0,04789105 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02366127 0,0478514 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02366127 0,04781182 ! ruffle organization GO:0031529 17 10 0,000 0,02366127 0,04777231 ! epithelial cell development GO:0002064 21 10 0,000 0,02366127 0,04773286 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02366127 0,04769347 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02366127 0,04765416 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02366127 0,0476149 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02366127 0,04757571 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02366127 0,04753659 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02366127 0,04749753 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02366127 0,04745853 ! motor axon guidance GO:0008045 22 10 0,000 0,02366127 0,0474196 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02366127 0,04738073 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02366127 0,04734193 ! protein heterooligomerization GO:0051291 17 10 0,000 0,02366127 0,04730318 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02366127 0,04726451 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02366127 0,04722589 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02366127 0,04718734 ! segment specification GO:0007379 15 10 0,000 0,02366127 0,04714885 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02366127 0,04711043 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02366127 0,04707206 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02366127 0,04703376 ! response to dsRNA GO:0043331 23 10 0,000 0,02366127 0,04699552 ! DNA ligation GO:0006266 18 10 0,000 0,02366127 0,04695734 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02366127 0,04691923 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02366127 0,04688118 ! melanosome localization GO:0032400 16 10 0,000 0,02366127 0,04684319 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02366127 0,04680526 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02366127 0,04676739 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02366127 0,04672958 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02366127 0,04669183 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02366127 0,04665415 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02366127 0,04661653 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02366127 0,04657896 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02366127 0,04654146 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02366127 0,04650402 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02366127 0,04646663 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02366127 0,04642931 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 14 10 0,000 0,02366127 0,04639205 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02366127 0,04635484 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02366127 0,0463177 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02366127 0,04628062 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02366127 0,04624359 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02366127 0,04620663 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02366127 0,04616972 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02366127 0,04613287 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02366127 0,04609609 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02366127 0,04605936 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,02366127 0,04602268 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,02366127 0,04598607 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02366127 0,04594952 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02366127 0,04591302 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02366127 0,04587658 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02366127 0,0458402 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02366127 0,04580388 ! response to nicotine GO:0035094 20 10 0,000 0,02366127 0,04576761 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02366127 0,0457314 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02366127 0,04569525 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,02404575 0,04640109 GO:0060538|skeletal muscle organ development, ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02599675 0,05012633 ! respiratory burst GO:0045730 17 11 0,000 0,02599675 0,0500868 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02599675 0,05004733 ! neuron fate specification GO:0048665 18 11 0,000 0,02599675 0,05000792 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02599675 0,04996857 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02599675 0,04992929 ! thyroid gland development GO:0030878 26 11 0,000 0,02599675 0,04989007 ! synapsis GO:0007129 14 11 0,000 0,02599675 0,04985091 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02599675 0,04981181 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02599675 0,04977277 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02599675 0,0497338 ! response to pain GO:0048265 27 11 0,000 0,02599675 0,04969488 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02599675 0,04965603 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02599675 0,04961723 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02599675 0,0495785 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02599675 0,04953983 ! bone resorption GO:0045453 16 11 0,000 0,02599675 0,04950121 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02599675 0,04946266 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02599675 0,04942417 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02599675 0,04938574 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02599675 0,04934736 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02599675 0,04930905 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02599675 0,0492708 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02599675 0,0492326 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02599675 0,04919447 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02599675 0,04915639 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02599675 0,04911837 ! UV protection GO:0009650 20 11 0,000 0,02599675 0,04908042 ! adult heart development GO:0007512 16 11 0,000 0,02599675 0,04904252 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02599675 0,04900467 ! macroautophagy GO:0016236 19 11 0,000 0,02599675 0,04896689 ! temperature homeostasis GO:0001659 18 11 0,000 0,02599675 0,04892917 ! behavioral fear response GO:0001662 27 11 0,000 0,02599675 0,0488915 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02599675 0,04885389 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02599675 0,04881634 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02599675 0,04877885 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02599675 0,04874141 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02599675 0,04870403 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02599675 0,04866671 ! regulation of organ growth GO:0046620 14 11 0,000 0,02599675 0,04862945 ! pigment granule localization GO:0051875 20 11 0,000 0,02599675 0,04859224 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02599675 0,04855509 ! vasoconstriction GO:0042310 20 11 0,000 0,02599675 0,048518 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02599675 0,04848096 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02599675 0,04844398 ! embryonic axis specification GO:0000578 19 11 0,000 0,02599675 0,04840706 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02599675 0,04837019 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02599675 0,04833338 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02599675 0,04829662 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02599675 0,04825992 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02599675 0,04822328 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02599675 0,04818669 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02599675 0,04815016 ! prophase GO:0051324 17 11 0,000 0,02599675 0,04811368 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02599675 0,04807726 ! nucleosome positioning GO:0016584 15 11 0,000 0,02599675 0,04804089 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02599675 0,04800458 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02599675 0,04796832 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02599675 0,04793212 ! acid secretion GO:0046717 20 11 0,000 0,02599675 0,04789597 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02599675 0,04785988 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02599675 0,04782384 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02599675 0,04778785 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02599675 0,04775192 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02599675 0,04771605 ! cholesterol efflux GO:0033344 21 11 0,000 0,02599675 0,04768022 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02599675 0,04764446 ! oocyte development GO:0048599 20 11 0,000 0,02599675 0,04760874 ! germ cell migration GO:0008354 26 11 0,000 0,02599675 0,04757308 ! embryonic gut development GO:0048566 19 11 0,000 0,02599675 0,04753747 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02599675 0,04750191 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02599675 0,04746641 ! activation of innate immune response GO:0002218 16 11 0,000 0,02599675 0,04743096 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02599675 0,04739557 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02599675 0,04736022 ! lysogeny GO:0030069 22 11 0,000 0,02599675 0,04732493 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02599675 0,04728969 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02599675 0,04725451 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02599675 0,04721937 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02599675 0,04718429 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0283267 0,05137501 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0283267 0,0513369 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,0283267 0,05129884 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,0283267 0,05126084 ! virus-host interaction GO:0019048 30 12 0,000 0,0283267 0,0512229 ! mating GO:0007618 17 12 0,000 0,0283267 0,05118501 ! protein complex disassembly GO:0043241 28 12 0,000 0,0283267 0,05114718 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0283267 0,05110941 ! hippocampus development GO:0021766 29 12 0,000 0,0283267 0,05107169 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,0283267 0,05103402 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0283267 0,05099642 ! T cell proliferation GO:0042098 32 12 0,000 0,0283267 0,05095886 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0283267 0,05092137 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0283267 0,05088392 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0283267 0,05084654 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0283267 0,05080921 ! drug transport GO:0015893 16 12 0,000 0,0283267 0,05077193 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0283267 0,05073471 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,0283267 0,05069754 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0283267 0,05066042 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0283267 0,05062336 ! focal adhesion formation GO:0048041 37 12 0,000 0,0283267 0,05058636 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0283267 0,05054941 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0283267 0,05051251 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0283267 0,05047567 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0283267 0,05043888 ! lipid digestion GO:0044241 21 12 0,000 0,0283267 0,05040214 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0283267 0,05036546 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0283267 0,05032883 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0283267 0,05029225 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0283267 0,05025573 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0283267 0,05021926 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0283267 0,05018284 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0283267 0,05014648 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,0283267 0,05011016 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0283267 0,05007391 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0283267 0,0500377 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0283267 0,05000154 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0283267 0,04996544 ! cranial nerve development GO:0021545 23 12 0,000 0,0283267 0,04992939 ! fucose catabolic process GO:0019317 25 12 0,000 0,0283267 0,04989339 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0283267 0,04985745 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0283267 0,04982155 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0283267 0,04978571 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0283267 0,04974992 ! zymogen activation GO:0031638 18 12 0,000 0,0283267 0,04971418 ! T cell homeostasis GO:0043029 28 12 0,000 0,0283267 0,04967849 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0283267 0,04964285 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0283267 0,04960727 ! oocyte differentiation GO:0009994 21 12 0,000 0,0283267 0,04957173 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0283267 0,04953625 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0283267 0,04950081 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,0283267 0,04946543 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,0283267 0,0494301 ! defense response to fungus GO:0050832 15 12 0,000 0,0283267 0,04939482 ! lamellipodium assembly GO:0030032 24 12 0,000 0,0283267 0,04935958 ! response to cold GO:0009409 17 12 0,000 0,0283267 0,0493244 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0283267 0,04928927 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0283267 0,04925419 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03065115 0,05325801 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03065115 0,05322016 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03065115 0,05318236 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03065115 0,05314461 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03065115 0,05310692 ! peroxisomal transport GO:0043574 28 13 0,000 0,03065115 0,05306928 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03065115 0,0530317 ! cartilage condensation GO:0001502 22 13 0,000 0,03065115 0,05299417 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,03065115 0,05295669 ! organelle fusion GO:0048284 36 13 0,000 0,03065115 0,05291927 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03065115 0,05288189 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,03065115 0,05284457 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,03065115 0,05280731 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,03065115 0,05277009 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03065115 0,05273293 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03065115 0,05269582 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03065115 0,05265876 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03065115 0,05262176 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03065115 0,0525848 ! methionine metabolic process GO:0006555 31 13 0,000 0,03065115 0,0525479 ! plasma membrane organization GO:0007009 27 13 0,000 0,03065115 0,05251105 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03065115 0,05247425 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03065115 0,05243751 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03065115 0,05240081 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,03065115 0,05236417 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,03065115 0,05232758 ! cytokine metabolic process GO:0042107 24 13 0,000 0,03065115 0,05229103 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,03065115 0,05225454 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,03065115 0,0522181 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,03065115 0,05218171 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,03065115 0,05214538 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03065115 0,05210909 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03065115 0,05207285 ! protein homotetramerization GO:0051289 24 13 0,000 0,03065115 0,05203666 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03065115 0,05200053 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03065115 0,05196444 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,03065115 0,05192841 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,03065115 0,05189242 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03065115 0,05185648 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03065115 0,0518206 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03065115 0,05178476 ! histone methylation GO:0016571 29 13 0,000 0,03065115 0,05174897 ! chromatin silencing GO:0006342 29 13 0,000 0,03065115 0,05171323 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,03065115 0,05167754 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03065115 0,0516419 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,03065115 0,05160631 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,03065115 0,05157077 ! spleen development GO:0048536 24 13 0,000 0,03065115 0,05153528 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,03065115 0,05149984 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03065115 0,05146444 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,03065115 0,05142909 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03065115 0,0513938 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,03065115 0,05135855 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03065115 0,05132334 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03065115 0,05128819 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03065115 0,05125309 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03065115 0,05121803 ! insulin secretion GO:0030073 24 13 0,000 0,03065115 0,05118302 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03065115 0,05114806 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,03065115 0,05111315 ! acrosome reaction GO:0007340 19 13 0,000 0,03065115 0,05107828 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03065115 0,05104346 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03065115 0,05100869 ! rRNA transcription GO:0009303 28 14 0,000 0,0329701 0,05483047 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,0329701 0,05479317 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,0329701 0,05475592 ! water transport GO:0006833 21 14 0,000 0,0329701 0,05471872 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,0329701 0,05468157 ! non-recombinational repair GO:0000726 29 14 0,000 0,0329701 0,05464448 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,0329701 0,05460743 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,0329701 0,05457043 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,0329701 0,05453349 ! RNA polyadenylation GO:0043631 32 14 0,000 0,0329701 0,05449659 ! lipid localization GO:0010876 32 14 0,000 0,0329701 0,05445974 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,0329701 0,05442294 ! regulated secretory pathway GO:0045055 24 14 0,000 0,0329701 0,0543862 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,0329701 0,0543495 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,0329701 0,05431285 ! arginine metabolic process GO:0006525 21 14 0,000 0,0329701 0,05427625 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,0329701 0,0542397 ! regulation of heart rate GO:0002027 25 14 0,000 0,0329701 0,0542032 ! fear response GO:0042596 34 14 0,000 0,0329701 0,05416675 ! organic alcohol transport GO:0015850 29 14 0,000 0,0329701 0,05413035 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,0329701 0,05409399 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,0329701 0,05405769 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0329701 0,05402143 ! neutral amino acid transport GO:0015804 28 14 0,000 0,0329701 0,05398523 ! bone mineralization GO:0030282 18 14 0,000 0,0329701 0,05394907 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,0329701 0,05391296 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,0329701 0,05387689 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,0329701 0,05384088 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,0329701 0,05380492 ! regulation of cellular pH GO:0030641 27 14 0,000 0,0329701 0,053769 ! ribosome assembly GO:0042255 18 14 0,000 0,0329701 0,05373313 ! cerebellum development GO:0021549 23 14 0,000 0,0329701 0,05369731 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,0329701 0,05366153 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,0329701 0,0536258 ! response to gamma radiation GO:0010332 30 14 0,000 0,0329701 0,05359013 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,0329701 0,05355449 ! NADP metabolic process GO:0006739 24 14 0,000 0,0329701 0,05351891 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,0329701 0,05348337 ! oxygen transport GO:0015671 22 14 0,000 0,0329701 0,05344788 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0329701 0,05341244 ! male genitalia development GO:0030539 26 14 0,000 0,0329701 0,05337704 ! regulation of RNA stability GO:0043487 33 14 0,000 0,0329701 0,05334169 ! regulation of axon extension GO:0030516 43 14 0,000 0,0329701 0,05330639 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,0329701 0,05327114 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,0329701 0,05323593 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03528357 0,05693379 ! lactation GO:0007595 30 15 0,000 0,03528357 0,05689621 ! reproductive cellular process GO:0048610 22 15 0,000 0,03528357 0,05685868 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03528357 0,0568212 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,03528357 0,05678377 ! superoxide anion generation GO:0042554 22 15 0,000 0,03528357 0,05674639 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,03528357 0,05670905 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,03528357 0,05667177 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,03528357 0,05663453 ! copper ion transport GO:0006825 22 15 0,000 0,03528357 0,05659735 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,03528357 0,05656021 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,03528357 0,05652312 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,03528357 0,05648608 ! sulfate transport GO:0008272 27 15 0,000 0,03528357 0,05644909 ! response to cAMP GO:0051591 25 15 0,000 0,03528357 0,05641215 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,03528357 0,05637525 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,03528357 0,05633841 ! response to hexose stimulus GO:0009746 25 15 0,000 0,03528357 0,05630161 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,03528357 0,05626486 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,03528357 0,05622816 ! vesicle coating GO:0006901 38 15 0,000 0,03528357 0,0561915 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,03528357 0,05615489 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,03528357 0,05611833 ! regulation of exocytosis GO:0017157 26 15 0,000 0,03528357 0,05608182 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,03528357 0,05604536 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,03528357 0,05600894 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,03528357 0,05597257 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,03528357 0,05593625 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,03528357 0,05589998 ! regulation of vasodilation GO:0042312 27 15 0,000 0,03528357 0,05586375 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,03528357 0,05582757 ! histone deacetylation GO:0016575 24 15 0,000 0,03528357 0,05579143 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03528357 0,05575534 ! water homeostasis GO:0030104 28 15 0,000 0,03528357 0,0557193 ! cofactor transport GO:0051181 30 15 0,000 0,03528357 0,05568331 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03528357 0,05564736 ! muscle maintenance GO:0046716 26 15 0,000 0,03528357 0,05561146 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,03528357 0,0555756 ! intestinal absorption GO:0050892 31 15 0,000 0,03528357 0,0555398 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03528357 0,05550403 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,03528357 0,05546832 ! heme biosynthetic process GO:0006783 33 15 0,000 0,03528357 0,05543264 ! cell killing GO:0001906 32 15 0,000 0,03528357 0,05539702 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,03528357 0,05536144 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,03528357 0,05532591 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,03528357 0,05529042 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,03528357 0,05525498 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,03528357 0,05521958 ! actin filament polymerization GO:0030041 27 15 0,000 0,03528357 0,05518423 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,03528357 0,05514892 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03759157 0,0587188 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03759157 0,05868128 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03759157 0,05864381 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03759157 0,05860638 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03759157 0,05856901 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03759157 0,05853168 ! bone remodeling GO:0046849 28 16 0,000 0,03759157 0,0584944 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03759157 0,05845716 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03759157 0,05841998 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03759157 0,05838284 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03759157 0,05834575 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03759157 0,0583087 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03759157 0,0582717 ! startle response GO:0001964 28 16 0,000 0,03759157 0,05823475 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03759157 0,05819785 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03759157 0,05816099 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03759157 0,05812418 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03759157 0,05808742 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03759157 0,0580507 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03759157 0,05801403 ! pituitary gland development GO:0021983 30 16 0,000 0,03759157 0,0579774 ! response to osmotic stress GO:0006970 27 16 0,000 0,03759157 0,05794082 ! lysosomal transport GO:0007041 31 16 0,000 0,03759157 0,05790429 ! fructose metabolic process GO:0006000 25 16 0,000 0,03759157 0,0578678 ! L-amino acid transport GO:0015807 33 16 0,000 0,03759157 0,05783136 ! stem cell development GO:0048864 46 16 0,000 0,03759157 0,05779497 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03759157 0,05775862 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03759157 0,05772232 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03759157 0,05768606 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03759157 0,05764985 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03759157 0,05761368 ! axon cargo transport GO:0008088 46 16 0,000 0,03759157 0,05757756 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03759157 0,05754148 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03759157 0,05750545 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,03759157 0,05746946 ! neuron recognition GO:0008038 40 16 0,000 0,03759157 0,05743352 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03759157 0,05739763 ! tissue regeneration GO:0042246 27 16 0,000 0,03759157 0,05736178 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03759157 0,05732597 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03759157 0,05729021 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03759157 0,05725449 ! biomineral formation GO:0031214 22 16 0,000 0,03759157 0,05721882 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03759157 0,05718319 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03759157 0,05714761 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03759157 0,05711207 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03759157 0,05707657 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03759157 0,05704112 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03759157 0,05700571 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03759157 0,05697035 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03759157 0,05693503 ! peptide hormone processing GO:0016486 27 16 0,000 0,03759157 0,05689975 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03989411 0,06034756 ! metencephalon development GO:0022037 32 17 0,000 0,03989411 0,06031022 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03989411 0,06027292 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03989411 0,06023567 ! signal complex assembly GO:0007172 47 17 0,000 0,03989411 0,06019846 ! endothelial cell migration GO:0043542 31 17 0,000 0,03989411 0,0601613 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03989411 0,06012419 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03989411 0,06008712 ! glial cell development GO:0021782 28 17 0,000 0,03989411 0,0600501 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03989411 0,06001312 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03989411 0,05997619 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03989411 0,05993931 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,03989411 0,05990247 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03989411 0,05986567 ! myoblast differentiation GO:0045445 50 17 0,000 0,03989411 0,05982892 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03989411 0,05979222 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03989411 0,05975556 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03989411 0,05971894 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03989411 0,05968237 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03989411 0,05964585 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03989411 0,05960937 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03989411 0,05957293 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03989411 0,05953654 ! membrane budding GO:0006900 42 17 0,000 0,03989411 0,05950019 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03989411 0,05946389 ! regulation of protein binding GO:0043393 33 17 0,000 0,03989411 0,05942763 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03989411 0,05939142 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03989411 0,05935525 ! genitalia development GO:0048806 32 17 0,000 0,03989411 0,05931912 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03989411 0,05928304 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03989411 0,059247 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03989411 0,059211 ! steroid catabolic process GO:0006706 34 17 0,000 0,03989411 0,05917505 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03989411 0,05913915 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03989411 0,05910328 ! gas transport GO:0015669 26 17 0,000 0,03989411 0,05906746 ! organic cation transport GO:0015695 32 17 0,000 0,03989411 0,05903169 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03989411 0,05899595 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03989411 0,05896026 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03989411 0,05892462 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,04219121 0,06227983 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04219121 0,06224222 ! limbic system development GO:0021761 40 18 0,000 0,04219121 0,06220466 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04219121 0,06216714 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04219121 0,06212967 ! adult walking behavior GO:0007628 36 18 0,000 0,04219121 0,06209224 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04219121 0,06205486 ! heart looping GO:0001947 34 18 0,000 0,04219121 0,06201752 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04219121 0,06198023 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04219121 0,06194298 ! centrosome cycle GO:0007098 26 18 0,000 0,04219121 0,06190578 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04219121 0,06186862 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,04219121 0,06183151 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,04219121 0,06179444 ! glycine metabolic process GO:0006544 30 18 0,000 0,04219121 0,06175741 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04219121 0,06172043 ! response to retinoic acid GO:0032526 31 18 0,000 0,04219121 0,0616835 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,04219121 0,06164661 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,04219121 0,06160976 ! DNA integration GO:0015074 32 18 0,000 0,04219121 0,06157295 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,04219121 0,06153619 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,04219121 0,06149948 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04219121 0,06146281 ! neural crest cell migration GO:0001755 41 18 0,000 0,04219121 0,06142618 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04219121 0,06138959 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04219121 0,06135305 GO:0046466|membrane lipid catabolic process, ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04219121 0,06131655 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,04219121 0,0612801 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,04219121 0,06124369 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,04219121 0,06120732 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04219121 0,06117099 ! detection of bacterium GO:0016045 22 18 0,000 0,04219121 0,06113471 ! nerve development GO:0021675 34 18 0,000 0,04219121 0,06109847 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04219121 0,06106228 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,04219121 0,06102612 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,04448288 0,06430276 ! negative regulation of defense response GO:0031348 27 19 0,000 0,04448288 0,06426473 ! neuron maturation GO:0042551 46 19 0,000 0,04448288 0,06422675 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,04448288 0,06418882 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,04448288 0,06415092 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,04448288 0,06411308 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,04448288 0,06407527 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,04448288 0,06403752 ! inositol metabolic process GO:0006020 33 19 0,000 0,04448288 0,0639998 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04448288 0,06396213 ! memory GO:0007613 34 19 0,000 0,04448288 0,06392451 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,04448288 0,06388693 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,04448288 0,06384939 GO:0042744|hydrogen peroxide catabolic process, ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,04448288 0,0638119 ! cerebral cortex development GO:0021987 40 19 0,000 0,04448288 0,06377445 ! pigmentation during development GO:0048066 42 19 0,000 0,04448288 0,06373705 ! response to vitamin A GO:0033189 32 19 0,000 0,04448288 0,06369969 ! heme metabolic process GO:0042168 40 19 0,000 0,04448288 0,06366237 ! neuromuscular junction development GO:0007528 43 19 0,000 0,04448288 0,0636251 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,04448288 0,06358787 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,04448288 0,06355068 ! response to fungus GO:0009620 26 19 0,000 0,04448288 0,06351354 ! peptide cross-linking GO:0018149 39 19 0,000 0,04448288 0,06347644 ! protein export from nucleus GO:0006611 40 19 0,000 0,04448288 0,06343938 ! heart process GO:0003015 32 19 0,000 0,04448288 0,06340237 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,04448288 0,0633654 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,04448288 0,06332848 ! visual learning GO:0008542 38 19 0,000 0,04448288 0,06329159 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,04448288 0,06325475 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,04448288 0,06321796 ! vitamin transport GO:0051180 31 19 0,000 0,04448288 0,0631812 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,04448288 0,06314449 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,04448288 0,06310782 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,04448288 0,06307119 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,04448288 0,06303461 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,04448288 0,06299807 ! cilium assembly GO:0042384 38 19 0,000 0,04448288 0,06296157 ! protein secretion GO:0009306 45 20 0,000 0,04676912 0,06615922 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04676912 0,06612093 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04676912 0,06608269 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04676912 0,06604449 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04676912 0,06600634 ! skin development GO:0043588 42 20 0,000 0,04676912 0,06596823 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04676912 0,06593016 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04676912 0,06589214 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,04676912 0,06585416 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04676912 0,06581623 ! response to vitamin GO:0033273 36 20 0,000 0,04676912 0,06577834 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04676912 0,06574049 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,04676912 0,06570269 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04676912 0,06566492 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04676912 0,06562721 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04676912 0,06558953 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04676912 0,0655519 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04676912 0,06551432 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04676912 0,06547677 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,04676912 0,06543927 ! actin filament bundle formation GO:0051017 47 20 0,000 0,04676912 0,06540181 ! body fluid secretion GO:0007589 33 20 0,000 0,04676912 0,0653644 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04676912 0,06532703 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04676912 0,0652897 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,04676912 0,06525241 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04676912 0,06521517 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04676912 0,06517796 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04676912 0,0651408 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,04676912 0,06510369 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04676912 0,06506661 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04676912 0,06502958 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04676912 0,06499259 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04676912 0,06495564 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04676912 0,06491873 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04676912 0,06488187 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04676912 0,06484504 ! negative regulation of translation GO:0017148 32 20 0,000 0,04676912 0,06480826 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04676912 0,06477152 ! regulation of cell killing GO:0031341 46 21 0,000 0,04904997 0,06789182 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04904997 0,06785338 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04904997 0,06781498 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04904997 0,06777662 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04904997 0,06773831 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04904997 0,06770004 ! ovarian follicle development GO:0001541 39 21 0,000 0,04904997 0,06766181 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04904997 0,06762363 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04904997 0,06758549 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04904997 0,06754739 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04904997 0,06750933 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04904997 0,06747132 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,04904997 0,06743335 ! sensory perception of pain GO:0019233 33 21 0,000 0,04904997 0,06739543 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04904997 0,06735754 ! diencephalon development GO:0021536 36 21 0,000 0,04904997 0,0673197 ! collagen fibril organization GO:0030199 62 21 0,000 0,04904997 0,0672819 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04904997 0,06724414 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04904997 0,06720643 ! collagen catabolic process GO:0030574 29 21 0,000 0,04904997 0,06716876 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04904997 0,06713113 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04904997 0,06709354 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04904997 0,067056 ! actin filament-based movement GO:0030048 47 21 0,000 0,04904997 0,06701849 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,04904997 0,06698103 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,05132541 0,07004915 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,05132541 0,07001004 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,05132541 0,06997097 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,05132541 0,06993195 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,05132541 0,06989297 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,05132541 0,06985403 ! microtubule-based transport GO:0010970 59 22 0,000 0,05132541 0,06981514 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,05132541 0,06977629 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,05132541 0,06973748 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,05132541 0,06969871 ! cellular response to starvation GO:0009267 37 22 0,000 0,05132541 0,06965999 ! vacuolar transport GO:0007034 41 22 0,000 0,05132541 0,06962131 ! central nervous system neuron development GO:0021954 47 22 0,000 0,05132541 0,06958268 ! fucose metabolic process GO:0006004 44 22 0,000 0,05132541 0,06954409 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,05132541 0,06950554 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,05132541 0,06946703 ! ureteric bud development GO:0001657 50 22 0,000 0,05132541 0,06942856 ! cell aging GO:0007569 48 22 0,000 0,05132541 0,06939014 ! stem cell differentiation GO:0048863 57 22 0,000 0,05132541 0,06935176 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,05132541 0,06931343 ! cytolysis GO:0019835 27 22 0,000 0,05132541 0,06927513 ! renal system process GO:0003014 42 22 0,000 0,05132541 0,06923688 ! vasodilation GO:0042311 40 22 0,000 0,05132541 0,06919867 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,05132541 0,0691605 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,05132541 0,06912237 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,05132541 0,06908429 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,05132541 0,06904625 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,05132541 0,06900825 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,05132541 0,06897029 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,05132541 0,06893237 ! sarcomere organization GO:0045214 32 22 0,000 0,05132541 0,0688945 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,05132541 0,06885666 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,05132541 0,06881887 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,05132541 0,06878112 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,05132541 0,06874341 ! gut development GO:0048565 44 22 0,000 0,05132541 0,06870575 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,05132541 0,06866812 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,05132541 0,06863053 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,05132541 0,06859299 ! protein stabilization GO:0050821 41 22 0,000 0,05132541 0,06855549 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,05359548 0,0715485 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,05359548 0,07150943 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,05359548 0,07147039 ! gluconeogenesis GO:0006094 38 23 0,000 0,05359548 0,0714314 ! glycerol metabolic process GO:0006071 40 23 0,000 0,05359548 0,07139245 ! viral genome replication GO:0019079 44 23 0,000 0,05359548 0,07135355 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,05359548 0,07131468 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,05359548 0,07127586 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,05359548 0,07123708 ! regeneration GO:0031099 42 23 0,000 0,05359548 0,07119835 ! axis specification GO:0009798 43 23 0,000 0,05359548 0,07115965 ! visual behavior GO:0007632 46 23 0,000 0,05359548 0,071121 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,05359548 0,07108239 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,05359548 0,07104382 ! response to ethanol GO:0045471 47 23 0,000 0,05359548 0,07100529 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,05359548 0,07096681 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,05359548 0,07092836 ! peroxisome organization GO:0007031 43 23 0,000 0,05359548 0,07088996 ! lysosome organization GO:0007040 47 23 0,000 0,05359548 0,0708516 ! vesicle targeting GO:0006903 49 23 0,000 0,05359548 0,07081328 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,05359548 0,07077501 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,05359548 0,07073677 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,05359548 0,07069858 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,05359548 0,07066042 ! fatty acid transport GO:0015908 47 23 0,000 0,05359548 0,07062231 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,05359548 0,07058424 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,05359548 0,07054621 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,05359548 0,07050822 ! cell-cell recognition GO:0009988 28 23 0,000 0,05359548 0,07047027 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,05359548 0,07043236 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,05359548 0,0703945 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,05586018 0,07332962 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,05586018 0,07329024 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,05586018 0,0732509 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,05586018 0,0732116 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,05586018 0,07317234 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,05586018 0,07313313 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,05586018 0,07309396 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,05586018 0,07305483 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,05586018 0,07301574 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,05586018 0,0729767 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,05586018 0,07293769 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,05586018 0,07289873 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,05586018 0,07285981 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,05586018 0,07282093 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,05586018 0,07278209 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,05586018 0,0727433 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,05586018 0,07270454 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,05586018 0,07266583 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,05586018 0,07262715 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,05586018 0,07258852 ! membrane depolarization GO:0051899 45 24 0,000 0,05586018 0,07254993 ! pallium development GO:0021543 56 24 0,000 0,05586018 0,07251138 ! oogenesis GO:0048477 44 24 0,000 0,05586018 0,07247287 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,05586018 0,07243441 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,05586018 0,07239598 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,05586018 0,07235759 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,05586018 0,07231925 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,05586018 0,07228094 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,05586018 0,07224268 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,05586018 0,07220446 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,05586018 0,07216627 ! regulation of amine transport GO:0051952 41 24 0,000 0,05586018 0,07212813 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,05586018 0,07209003 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,05811952 0,07496621 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,05811952 0,07492665 ! leukocyte adhesion GO:0007159 55 25 0,000 0,05811952 0,07488713 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,05811952 0,07484765 ! phototransduction GO:0007602 37 25 0,000 0,05811952 0,07480822 ! keratinization GO:0031424 37 25 0,000 0,05811952 0,07476882 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,05811952 0,07472947 ! vacuole organization GO:0007033 49 25 0,000 0,05811952 0,07469016 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,05811952 0,07465089 ! receptor metabolic process GO:0043112 53 25 0,000 0,05811952 0,07461166 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,05811952 0,07457248 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,05811952 0,07453333 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,05811952 0,07449423 ! immunoglobulin production GO:0002377 62 25 0,000 0,05811952 0,07445516 GO:0002440|production of molecular mediator of immune response, ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,05811952 0,07441614 ! liver development GO:0001889 55 25 0,000 0,05811952 0,07437716 ! protein tetramerization GO:0051262 57 25 0,000 0,05811952 0,07433822 ! myelination GO:0042552 50 26 0,000 0,06037352 0,07718081 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,06037352 0,07714044 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,06037352 0,07710012 ! molting cycle process GO:0022404 52 26 0,000 0,06037352 0,07705983 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,06037352 0,07701959 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,06037352 0,0769794 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,06037352 0,07693924 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,06037352 0,07689912 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,06037352 0,07685905 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,06037352 0,07681902 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,06037352 0,07677903 ! digestive system process GO:0022600 49 26 0,000 0,06037352 0,07673908 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,06037352 0,07669918 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,06037352 0,07665931 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,06037352 0,07661949 ! osteoblast differentiation GO:0001649 63 26 0,000 0,06037352 0,07657971 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,06037352 0,07653997 ! neural crest cell development GO:0014032 59 26 0,000 0,06037352 0,07650027 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,06037352 0,07646061 ! negative regulation of cell development GO:0010721 83 26 0,000 0,06037352 0,076421 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,06037352 0,07638142 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,06037352 0,07634188 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,06037352 0,07630239 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,06037352 0,07626294 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,06037352 0,07622353 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,06037352 0,07618415 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,06037352 0,07614482 ! telomere organization GO:0032200 46 26 0,000 0,06037352 0,07610553 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,06037352 0,07606628 ! neural tube closure GO:0001843 58 26 0,000 0,06037352 0,07602707 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,06037352 0,0759879 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,06037352 0,07594877 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,06037352 0,07590969 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,06262219 0,07869651 ! embryonic pattern specification GO:0009880 49 27 0,000 0,06262219 0,07865605 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,06262219 0,07861563 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,06262219 0,07857525 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,06262219 0,07853492 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,06262219 0,07849462 ! iron ion transport GO:0006826 65 27 0,000 0,06262219 0,07845437 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,06262219 0,07841416 ! superoxide metabolic process GO:0006801 41 27 0,000 0,06262219 0,07837399 ! tube lumen formation GO:0035148 59 27 0,000 0,06262219 0,07833386 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,06262219 0,07829377 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,06262219 0,07825372 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,06262219 0,07821371 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,06262219 0,07817375 ! response to starvation GO:0042594 47 27 0,000 0,06262219 0,07813382 ! response to toxin GO:0009636 49 27 0,000 0,06262219 0,07809394 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,06262219 0,07805409 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,06262219 0,07801429 ! leukocyte proliferation GO:0070661 59 27 0,000 0,06262219 0,07797453 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,06262219 0,0779348 ! neuron fate commitment GO:0048663 52 28 0,000 0,06486555 0,08068561 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,06486555 0,08064454 ! vesicle docking GO:0048278 55 28 0,000 0,06486555 0,08060352 ! circadian rhythm GO:0007623 56 28 0,000 0,06486555 0,08056255 ! dendrite development GO:0016358 67 28 0,000 0,06486555 0,08052161 ! fat cell differentiation GO:0045444 57 28 0,000 0,06486555 0,08048072 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,06486555 0,08043986 ! sperm motility GO:0030317 37 28 0,000 0,06486555 0,08039905 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,06486555 0,08035828 ! base-excision repair GO:0006284 41 28 0,000 0,06486555 0,08031755 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,06486555 0,08027686 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,06486555 0,08023622 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,06486555 0,08019561 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,06486555 0,08015505 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,06486555 0,08011452 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,06486555 0,08007404 ! glutathione metabolic process GO:0006749 42 28 0,000 0,06486555 0,0800336 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,06486555 0,0799932 ! lipid oxidation GO:0034440 48 28 0,000 0,06486555 0,07995284 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,06486555 0,07991252 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,06486555 0,07987224 ! translational initiation GO:0006413 66 29 0,000 0,06710359 0,08258644 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,06710359 0,08254485 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,06710359 0,08250331 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,06710359 0,08246181 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,06710359 0,08242035 ! primary neural tube formation GO:0014020 61 29 0,000 0,06710359 0,08237893 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,06710359 0,08233756 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,06710359 0,08229622 ! synaptogenesis GO:0007416 46 29 0,000 0,06710359 0,08225493 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,06710359 0,08221368 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,06710359 0,08217247 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,06710359 0,0821313 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,06710359 0,08209017 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,06933634 0,08477912 ! phenol metabolic process GO:0018958 56 30 0,000 0,06933634 0,08473671 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,06933634 0,08469434 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,06933634 0,08465202 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,06933634 0,08460973 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,06933634 0,08456749 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,06933634 0,08452529 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,06933634 0,08448314 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,06933634 0,08444102 ! myofibril assembly GO:0030239 50 30 0,000 0,06933634 0,08439895 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,06933634 0,08435692 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,06933634 0,08431493 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,06933634 0,08427298 ! cell fate determination GO:0001709 64 30 0,000 0,06933634 0,08423107 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,06933634 0,08418921 ! phospholipid transport GO:0015914 65 30 0,000 0,06933634 0,08414739 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,06933634 0,0841056 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,06933634 0,08406386 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,06933634 0,08402217 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,06933634 0,08398051 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,06933634 0,08393889 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,06933634 0,08389732 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,07156381 0,0865497 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,07156381 0,08650688 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,07156381 0,08646409 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,07156381 0,08642135 ! regulation of innate immune response GO:0045088 57 31 0,000 0,07156381 0,08637866 ! ovulation cycle process GO:0022602 55 31 0,000 0,07156381 0,086336 ! male gonad development GO:0008584 56 31 0,000 0,07156381 0,08629339 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,07156381 0,08625081 ! detection of light stimulus GO:0009583 44 31 0,000 0,07156381 0,08620828 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,07156381 0,0861658 ! natural killer cell activation GO:0030101 50 31 0,000 0,07156381 0,08612335 ! ensheathment of neurons GO:0007272 64 31 0,000 0,07156381 0,08608095 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,07156381 0,08603858 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,07156381 0,08599626 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,07156381 0,08595398 ! eye morphogenesis GO:0048592 65 31 0,000 0,07156381 0,08591174 ! response to heat GO:0009408 54 31 0,000 0,07156381 0,08586955 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,07156381 0,08582739 ! collagen metabolic process GO:0032963 49 32 0,000 0,07378602 0,08844909 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,07378602 0,08840571 ! spindle organization GO:0007051 50 32 0,000 0,07378602 0,08836237 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,07378602 0,08831908 ! metanephros development GO:0001656 81 32 0,000 0,07378602 0,08827583 ! muscle cell development GO:0055001 52 32 0,000 0,07378602 0,08823262 ! mesoderm formation GO:0001707 73 32 0,000 0,07378602 0,08818945 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,07378602 0,08814633 ! ovulation cycle GO:0042698 57 32 0,000 0,07378602 0,08810325 ! peripheral nervous system development GO:0007422 68 32 0,000 0,07378602 0,08806021 ! BMP signaling pathway GO:0030509 71 32 0,000 0,07378602 0,08801721 ! hindbrain development GO:0030902 65 32 0,000 0,07378602 0,08797425 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,07378602 0,08793134 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,07378602 0,08788846 ! gene silencing GO:0016458 71 32 0,000 0,07378602 0,08784563 ! regulation of pH GO:0006885 56 33 0,000 0,07600296 0,09044094 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,07600296 0,0903969 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,07600296 0,09035291 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,07600296 0,09030897 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,07600296 0,09026507 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,07600296 0,0902212 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,07600296 0,09017739 ! response to ionizing radiation GO:0010212 74 33 0,000 0,07600296 0,09013361 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,07600296 0,09008988 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,07600296 0,09004619 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,07600296 0,09000254 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,07600296 0,08995893 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,07600296 0,08991537 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,07821467 0,09248714 ! glial cell differentiation GO:0010001 67 34 0,000 0,07821467 0,09244239 ! post-embryonic development GO:0009791 76 34 0,000 0,07821467 0,09239769 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,07821467 0,09235303 ! cholesterol transport GO:0030301 62 34 0,000 0,07821467 0,09230842 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,07821467 0,09226385 ! spliceosome assembly GO:0000245 75 34 0,000 0,07821467 0,09221932 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,07821467 0,09217483 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,07821467 0,09213039 ! formation of primary germ layer GO:0001704 76 34 0,000 0,07821467 0,09208599 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,07821467 0,09204163 ! adult locomotory behavior GO:0008344 62 34 0,000 0,07821467 0,09199732 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,08042114 0,09454708 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,08042114 0,0945016 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,08042114 0,09445617 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,08042114 0,09441078 ! membrane docking GO:0022406 69 35 0,000 0,08042114 0,09436543 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,08042114 0,09432013 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,08042114 0,09427487 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,08042114 0,09422966 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,08042114 0,09418448 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,08042114 0,09413936 ! ceramide metabolic process GO:0006672 72 35 0,000 0,08042114 0,09409427 ! telencephalon development GO:0021537 81 35 0,000 0,08042114 0,09404923 ! sterol transport GO:0015918 63 35 0,000 0,08042114 0,09400423 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,08042114 0,09395927 ! vesicle localization GO:0051648 70 35 0,000 0,08042114 0,09391436 ! regulation of muscle development GO:0048634 82 36 0,000 0,08262239 0,09643884 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,08262239 0,09639278 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,08262239 0,09634677 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,08262239 0,09630081 ! positive regulation of cell development GO:0010720 85 36 0,000 0,08262239 0,09625488 ! protein targeting to membrane GO:0006612 75 36 0,000 0,08262239 0,096209 ! regulation of proteolysis GO:0030162 77 36 0,000 0,08262239 0,09616317 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,08262239 0,09611738 ! aerobic respiration GO:0009060 56 36 0,000 0,08262239 0,09607163 ! cytokine production GO:0001816 68 36 0,000 0,08262239 0,09602592 ! embryonic organ development GO:0048568 67 36 0,000 0,08262239 0,09598026 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,08262239 0,09593464 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,08262239 0,09588907 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,08481843 0,09839099 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,08481843 0,09834429 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,08481843 0,09829764 ! odontogenesis GO:0042476 74 37 0,000 0,08481843 0,09825103 ! actomyosin structure organization GO:0031032 68 37 0,000 0,08481843 0,09820447 ! tissue remodeling GO:0048771 78 37 0,000 0,08481843 0,09815795 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,08481843 0,09811147 ! female gonad development GO:0008585 71 37 0,000 0,08481843 0,09806504 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,08481843 0,09801865 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,08481843 0,0979723 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,08481843 0,097926 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,08481843 0,09787975 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,08700928 0,10036056 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,08700928 0,1003132 ! meiosis I GO:0007127 74 38 0,000 0,08700928 0,10026588 ! organic anion transport GO:0015711 82 38 0,000 0,08700928 0,10021861 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,08700928 0,10017138 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,08700928 0,10012419 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,08700928 0,10007705 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,08700928 0,10002996 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,08700928 0,09998291 ! regulation of protein stability GO:0031647 77 38 0,000 0,08700928 0,0999359 ! spermatid development GO:0007286 69 38 0,000 0,08700928 0,09988894 ! glycogen metabolic process GO:0005977 63 38 0,000 0,08700928 0,09984202 ! pigment metabolic process GO:0042440 87 38 0,000 0,08700928 0,09979515 ! neural tube formation GO:0001841 79 38 0,000 0,08700928 0,09974832 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,08919494 0,10220602 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,08919494 0,10215811 ! negative regulation of binding GO:0051100 71 39 0,000 0,08919494 0,10211024 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,08919494 0,10206241 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,08919494 0,10201463 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,08919494 0,10196689 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,08919494 0,1019192 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,08919494 0,10187155 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,08919494 0,10182395 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,08919494 0,10177639 ! glucan metabolic process GO:0044042 64 39 0,000 0,08919494 0,10172887 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,09137544 0,10416714 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,09137544 0,10411856 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,09137544 0,10407002 ! learning GO:0007612 82 40 0,000 0,09137544 0,10402152 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,09137544 0,10397307 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,09137544 0,10392467 ! mismatch repair GO:0006298 58 40 0,000 0,09137544 0,10387631 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,09137544 0,10382799 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,09137544 0,10377973 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,09137544 0,1037315 ! RNA export from nucleus GO:0006405 61 41 0,000 0,09355077 0,10615166 ! mRNA catabolic process GO:0006402 79 41 0,000 0,09355077 0,10610238 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,09355077 0,10605315 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,09355077 0,10600396 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,09355077 0,10595481 ! gliogenesis GO:0042063 91 41 0,000 0,09355077 0,10590571 ! feeding behavior GO:0007631 69 41 0,000 0,09355077 0,10585666 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,09355077 0,10580765 ! mesenchymal cell development GO:0014031 94 41 0,000 0,09355077 0,10575869 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,09355077 0,10570977 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,09355077 0,1056609 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,09355077 0,10561208 ! spermatid differentiation GO:0048515 73 41 0,000 0,09355077 0,10556329 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,09355077 0,10551456 ! RNA modification GO:0009451 64 41 0,000 0,09355077 0,10546587 ! organic ether metabolic process GO:0018904 59 42 0,000 0,09572096 0,10786268 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,09572096 0,10781296 ! T cell differentiation GO:0030217 93 42 0,000 0,09572096 0,10776327 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,09572096 0,10771363 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,09572096 0,10766404 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,09572096 0,1076145 ! cytokinesis GO:0000910 84 42 0,000 0,09572096 0,107565 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,09572096 0,10751554 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,09788601 0,10989684 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,09788601 0,10984636 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,09788601 0,10979593 ! regulation of tube size GO:0035150 76 43 0,000 0,09788601 0,10974554 GO:0050880|regulation of blood vessel size, ! glucose transport GO:0015758 66 43 0,000 0,09788601 0,1096952 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,09788601 0,1096449 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,09788601 0,10959465 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,09788601 0,10954445 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,09788601 0,10949429 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,09788601 0,10944418 ! ion transmembrane transport GO:0034220 79 43 0,000 0,09788601 0,10939411 ! neuron migration GO:0001764 85 43 0,000 0,09788601 0,10934409 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,09788601 0,10929412 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,10004594 0,11165474 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,10004594 0,11160376 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,10004594 0,11155282 ! hexose transport GO:0008645 68 44 0,000 0,10004594 0,11150193 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,10004594 0,11145109 ! striated muscle contraction GO:0006941 85 44 0,000 0,10004594 0,11140029 ! phagocytosis GO:0006909 105 44 0,000 0,10004594 0,11134954 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,10004594 0,11129883 ! double-strand break repair GO:0006302 85 44 0,000 0,10004594 0,11124817 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,10220076 0,11359257 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,10220076 0,11354091 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,10220076 0,1134893 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,10220076 0,11343774 ! B cell differentiation GO:0030183 124 45 0,000 0,10220076 0,11338622 ! female gamete generation GO:0007292 71 45 0,000 0,10220076 0,11333475 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,10220076 0,11328333 ! polyol metabolic process GO:0019751 77 45 0,000 0,10220076 0,11323195 ! developmental growth GO:0048589 88 45 0,000 0,10220076 0,11318063 ! maintenance of location in cell GO:0051651 101 45 0,000 0,10220076 0,11312934 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,10435048 0,11545662 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,10435048 0,11540436 ! glycolysis GO:0006096 71 46 0,000 0,10435048 0,11535214 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,10435048 0,11529997 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,10435048 0,11524784 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,10435048 0,11519576 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,10435048 0,11514373 ! neural tube development GO:0021915 91 47 0,000 0,10649512 0,11745714 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,10649512 0,11740414 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,10863467 0,11970885 ! mitochondrial transport GO:0006839 94 48 0,000 0,10863467 0,11965487 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,10863467 0,11960095 ! endosome transport GO:0016197 127 48 0,000 0,10863467 0,11954708 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,10863467 0,11949325 ! male sex differentiation GO:0046661 93 48 0,000 0,10863467 0,11943947 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,10863467 0,11938574 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,10863467 0,11933206 ! response to calcium ion GO:0051592 94 49 0,000 0,11076917 0,12162206 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,11076917 0,12156742 ! JNK cascade GO:0007254 106 49 0,000 0,11076917 0,12151283 ! protein homooligomerization GO:0051260 84 49 0,000 0,11076917 0,1214583 ! regulation of action potential GO:0001508 102 50 0,000 0,11289861 0,12373769 ! regulation of ion transport GO:0043269 86 50 0,000 0,11289861 0,1236822 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,11289861 0,12362677 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,11289861 0,12357138 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,11289861 0,12351604 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,11289861 0,12346075 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,11502302 0,12572762 ! response to temperature stimulus GO:0009266 84 51 0,000 0,11502302 0,12567139 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,11502302 0,12561521 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,1171424 0,1278726 ! Notch signaling pathway GO:0007219 111 52 0,000 0,1171424 0,12781549 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,1171424 0,12775843 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,1171424 0,12770142 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,1171424 0,12764446 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,1171424 0,12758755 ! excretion GO:0007588 87 52 0,000 0,1171424 0,12753069 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,1171424 0,12747389 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,1171424 0,12741713 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,1171424 0,12736042 ! amino acid activation GO:0043038 98 52 0,000 0,1171424 0,12730377 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,11925676 0,12954391 ! positive regulation of growth GO:0045927 96 53 0,000 0,11925676 0,12948634 ! inner ear development GO:0048839 89 53 0,000 0,11925676 0,12942881 ! chromatin remodeling GO:0006338 122 53 0,000 0,11925676 0,12937134 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,11925676 0,12931392 ! vesicle organization GO:0016050 127 53 0,000 0,11925676 0,12925655 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,11925676 0,12919923 ! synapse organization GO:0050808 102 53 0,000 0,11925676 0,12914196 ! regulation of translational initiation GO:0006446 87 54 0,000 0,12136611 0,13136793 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,12136611 0,13130975 ! neuromuscular process GO:0050905 107 54 0,000 0,12136611 0,13125162 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,12136611 0,13119355 ! membrane fusion GO:0006944 122 54 0,000 0,12136611 0,13113552 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,12136611 0,13107755 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,12136611 0,13101963 ! RNA catabolic process GO:0006401 103 55 0,000 0,12347048 0,1332325 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,12347048 0,13317368 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,12347048 0,13311491 ! cell recognition GO:0008037 98 55 0,000 0,12347048 0,13305619 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,12347048 0,13299752 ! cell maturation GO:0048469 107 55 0,000 0,12347048 0,13293891 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,12347048 0,13288034 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,12347048 0,13282183 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,12556986 0,13502076 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,12556986 0,13496136 ! glucose catabolic process GO:0006007 88 56 0,000 0,12556986 0,13490201 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,12556986 0,13484271 ! RNA elongation GO:0006354 90 56 0,000 0,12556986 0,13478347 ! chloride transport GO:0006821 102 57 0,000 0,12766427 0,13697138 ! muscle fiber development GO:0048747 131 57 0,000 0,12766427 0,13691125 ! heart morphogenesis GO:0003007 105 57 0,000 0,12766427 0,13685117 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,12766427 0,13679115 ! regulation of actin filament length GO:0030832 118 58 0,000 0,12975373 0,13896903 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,12975373 0,13890813 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,12975373 0,13884729 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,12975373 0,1387865 ! aging GO:0007568 112 58 0,000 0,12975373 0,13872576 ! gastrulation GO:0007369 122 58 0,000 0,12975373 0,13866508 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,12975373 0,13860444 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,12975373 0,13854387 ! maintenance of location GO:0051235 124 58 0,000 0,12975373 0,13848334 ! nuclear export GO:0051168 110 59 0,000 0,13183824 0,14064665 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,13391782 0,14280281 ! regulation of endocytosis GO:0030100 104 60 0,000 0,13391782 0,1427405 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,13391782 0,14267825 ! adult behavior GO:0030534 104 60 0,000 0,13391782 0,14261605 ! kidney development GO:0001822 133 60 0,000 0,13391782 0,14255391 ! regulation of cellular component size GO:0032535 125 61 0,000 0,13599247 0,1446993 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,13599247 0,14463631 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,13599247 0,14457337 ! camera-type eye development GO:0043010 126 61 0,000 0,13599247 0,14451048 ! proton transport GO:0015992 117 61 0,000 0,13599247 0,14444765 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,13806221 0,14658235 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,13806221 0,14651867 ! tRNA processing GO:0008033 102 62 0,000 0,13806221 0,14645505 ! regulation of mitosis GO:0007088 112 63 0,000 0,14012705 0,1485809 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,14012705 0,14851644 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,14012705 0,14845203 ! hydrogen transport GO:0006818 121 64 0,000 0,14218701 0,15056908 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,14218701 0,15050384 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,14218701 0,15043866 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,14424208 0,15254693 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,14424208 0,15248092 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,14424208 0,15241497 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,14424208 0,15234907 ! gonad development GO:0008406 115 66 0,000 0,14629229 0,15444774 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,14629229 0,15438102 ! activation of MAPK activity GO:0000187 124 67 0,000 0,14833765 0,15647188 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,14833765 0,15640435 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,14833765 0,15633688 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,14833765 0,15626946 ! secondary metabolic process GO:0019748 125 67 0,000 0,14833765 0,1562021 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,15037816 0,15828257 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,15037816 0,15821441 ! hexose catabolic process GO:0019320 113 68 0,000 0,15037816 0,1581463 ! extracellular matrix organization GO:0030198 146 68 0,000 0,15037816 0,15807825 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,15037816 0,15801026 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! adaptive immune response GO:0002250 126 68 0,000 0,15037816 0,15794233 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,15037816 0,15787445 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,15241385 0,15994288 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,15241385 0,15987421 ! urogenital system development GO:0001655 149 69 0,000 0,15241385 0,15980559 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,15241385 0,15973703 ! developmental maturation GO:0021700 128 69 0,000 0,15241385 0,15966854 ! single fertilization GO:0007338 83 69 0,000 0,15241385 0,1596001 ! cell redox homeostasis GO:0045454 114 70 0,000 0,15444471 0,16165742 ! germ cell development GO:0007281 133 70 0,000 0,15444471 0,16158819 ! activation of immune response GO:0002253 120 70 0,000 0,15444471 0,16151902 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,15444471 0,1614499 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,15647076 0,16349789 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,15647076 0,16342799 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,15647076 0,16335815 ! appendage morphogenesis GO:0035107 150 72 0,000 0,15849202 0,16539769 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,15849202 0,16532707 ! actin filament organization GO:0007015 167 72 0,000 0,15849202 0,16525651 ! B cell activation GO:0042113 179 72 0,000 0,15849202 0,165186 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,15849202 0,16511556 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,15849202 0,16504518 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,15849202 0,16497486 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,15849202 0,1649046 ! appendage development GO:0048736 151 73 0,000 0,16050848 0,16693156 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,16050848 0,16686052 ! amino acid transport GO:0006865 148 74 0,000 0,16252018 0,16887996 ! transition metal ion transport GO:0000041 143 75 0,000 0,16452711 0,17089274 ! reproductive structure development GO:0048608 131 75 0,000 0,16452711 0,17082011 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,16452711 0,17074755 ! eye development GO:0001654 155 75 0,000 0,16452711 0,17067504 ! axon guidance GO:0007411 162 75 0,000 0,16452711 0,1706026 ! rhythmic process GO:0048511 142 75 0,000 0,16452711 0,17053022 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,16652928 0,17253225 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,16652928 0,17245911 ! learning or memory GO:0007611 161 76 0,000 0,16652928 0,17238603 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,16652928 0,17231302 ! regulation of blood pressure GO:0008217 134 76 0,000 0,16652928 0,17224007 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,16652928 0,17216718 ! amine catabolic process GO:0009310 136 77 0,000 0,16852672 0,17415853 ! neurotransmitter transport GO:0006836 142 77 0,000 0,16852672 0,17408489 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,16852672 0,17401131 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,16852672 0,1739378 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,16852672 0,17386435 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,16852672 0,17379095 ! regulation of catabolic process GO:0009894 173 77 0,000 0,16852672 0,17371762 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,17051942 0,17569757 ! antigen processing and presentation GO:0019882 117 78 0,000 0,17051942 0,1756235 ! fertilization GO:0009566 99 78 0,000 0,17051942 0,17554949 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,17250741 0,17752131 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,17250741 0,17744657 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,17250741 0,17737188 ! protein oligomerization GO:0051259 149 79 0,000 0,17250741 0,17729726 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,17250741 0,1772227 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,17449068 0,17918484 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,17449068 0,17910955 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,17449068 0,17903433 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,17449068 0,17895917 ! meiosis GO:0007126 143 81 0,000 0,17646926 0,18091246 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,17646926 0,18083658 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,17646926 0,18076076 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,17844315 0,18270604 ! protein import into nucleus GO:0006606 174 82 0,000 0,17844315 0,1826295 ! meiotic cell cycle GO:0051321 144 82 0,000 0,17844315 0,18255302 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,18041237 0,18449034 ! exocytosis GO:0006887 153 83 0,000 0,18041237 0,18441314 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,18041237 0,18433602 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,18041237 0,18425895 ! nuclear import GO:0051170 177 83 0,000 0,18041237 0,18418195 ! inorganic anion transport GO:0015698 156 83 0,000 0,18041237 0,18410502 ! response to metal ion GO:0010038 158 84 0,000 0,18237692 0,18603207 ! T cell activation GO:0042110 189 84 0,000 0,18237692 0,18595443 ! response to nutrient GO:0007584 135 84 0,000 0,18237692 0,18587685 ! digestion GO:0007586 130 84 0,000 0,18237692 0,18579934 ! regulation of ligase activity GO:0051340 147 84 0,000 0,18237692 0,18572189 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,18433682 0,18763952 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,18433682 0,18756137 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,18433682 0,18748328 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,18433682 0,18740526 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,18629207 0,18931428 ! regulation of lyase activity GO:0051339 169 86 0,000 0,18629207 0,18923556 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,18824269 0,19113753 ! alcohol catabolic process GO:0046164 142 87 0,000 0,18824269 0,19105812 ! nucleosome assembly GO:0006334 126 87 0,000 0,18824269 0,19097878 ! cellular respiration GO:0045333 143 88 0,000 0,19018869 0,19287297 ! amine biosynthetic process GO:0009309 146 88 0,000 0,19018869 0,19279294 ! sensory perception of smell GO:0007608 117 88 0,000 0,19018869 0,19271297 ! chromatin assembly GO:0031497 128 88 0,000 0,19018869 0,19263308 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,19213008 0,19451877 ! tube morphogenesis GO:0035239 194 89 0,000 0,19213008 0,19443819 ! cellular defense response GO:0006968 123 89 0,000 0,19213008 0,19435768 ! protein localization in nucleus GO:0034504 192 89 0,000 0,19213008 0,19427723 ! regulation of neurological system process GO:0031644 175 89 0,000 0,19213008 0,19419685 ! response to inorganic substance GO:0010035 173 90 0,000 0,19406688 0,19607336 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,19406688 0,1959923 ! response to unfolded protein GO:0006986 139 90 0,000 0,19406688 0,19591131 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,19599908 0,19778015 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,1979267 0,19964283 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,1979267 0,19956044 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,19984976 0,20141624 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,19984976 0,20133318 ! vitamin metabolic process GO:0006766 153 93 0,000 0,19984976 0,20125019 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,20176826 0,20309842 ! sterol metabolic process GO:0016125 166 94 0,000 0,20176826 0,20301477 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,20176826 0,20293119 ! regulation of membrane potential GO:0042391 179 94 0,000 0,20176826 0,20284768 ! nucleosome organization GO:0034728 143 95 0,000 0,20368222 0,20468764 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,20368222 0,20460348 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,20368222 0,20451938 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,20368222 0,20443536 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,20368222 0,2043514 ! sex differentiation GO:0007548 171 96 0,000 0,20559164 0,20618242 ! response to protein stimulus GO:0051789 158 96 0,000 0,20559164 0,20609781 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,20749653 0,20792208 ! forebrain development GO:0030900 210 98 0,000 0,20939691 0,20974033 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,20939691 0,20965437 ! mRNA transport GO:0051028 185 100 0,000 0,21318417 0,21335884 ! positive regulation of immune response GO:0050778 175 100 0,000 0,21318417 0,21327147 ! hormone metabolic process GO:0042445 171 100 0,000 0,21318417 0,21318417