pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1098-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 12 6 2,000 5,663E-07 1,362E-03 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 5,663E-07 6,812E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipid kinase activity GO:0043550 13 7 2,000 9,888E-07 7,93E-04 ! macrophage differentiation GO:0030225 11 7 2,000 9,888E-07 5,947E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 3,000 1,025E-06 4,934E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,578E-06 6,33E-04 ! protein heterooligomerization GO:0051291 16 9 2,000 2,362E-06 8,12E-04 ! nucleus localization GO:0051647 19 11 2,000 4,62E-06 1,389E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 6,146E-06 1,643E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 1,259E-05 3,029E-03 ! filopodium assembly GO:0046847 32 16 2,000 1,55E-05 3,391E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,878E-05 3,766E-03 ! microspike assembly GO:0030035 36 17 2,000 1,878E-05 3,477E-03 ! response to UV GO:0009411 104 53 3,000 2,222E-05 3,818E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,128E-05 5,017E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 4,827E-05 7,258E-03 ! protein tetramerization GO:0051262 52 24 2,000 5,504E-05 7,79E-03 ! interaction with host GO:0051701 62 25 2,000 6,241E-05 8,342E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 7,039E-05 8,914E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 7,039E-05 8,468E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 7,901E-05 9,052E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 7,901E-05 8,641E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 8,83E-05 9,236E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 9,376E-05 9,4E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 9,376E-05 9,024E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 9,376E-05 8,677E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 9,376E-05 8,355E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 9,826E-05 8,444E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 9,826E-05 8,152E-03 ! protein oligomerization GO:0051259 139 78 3,000 1,02E-04 8,184E-03 ! response to drug GO:0042493 143 82 3,000 1,239E-04 9,62E-03 ! negative regulation of growth GO:0045926 155 84 3,000 1,361E-04 0,01023236 ! male sex determination GO:0030238 15 6 1,000 1,404E-04 0,0102337 ! negative regulation of multicellular organism growth GO:0040015 8 6 1,000 1,404E-04 9,933E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,404E-04 9,649E-03 ! DNA damage checkpoint GO:0000077 71 33 2,000 1,454E-04 9,719E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 1,591E-04 0,01034787 ! DNA integrity checkpoint GO:0031570 75 36 2,000 1,89E-04 0,01196835 ! regulation of helicase activity GO:0051095 15 7 1,000 1,961E-04 0,0120986 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,961E-04 0,01179614 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,961E-04 0,01150843 ! B cell lineage commitment GO:0002326 21 7 1,000 1,961E-04 0,01123442 ! T cell lineage commitment GO:0002360 16 7 1,000 1,961E-04 0,01097315 ! response to tumor cell GO:0002347 13 7 1,000 1,961E-04 0,01072376 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,961E-04 0,01048546 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 2,016E-04 0,01054559 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 2,052E-04 0,01050684 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 2,052E-04 0,01028795 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 2,188E-04 0,0107438 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 2,223E-04 0,01069905 ! leukocyte differentiation GO:0002521 202 96 3,000 2,278E-04 0,01074598 ! interphase GO:0051325 213 98 3,000 2,465E-04 0,01140664 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,61E-04 0,01184644 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,61E-04 0,01162706 ! ER overload response GO:0006983 12 8 1,000 2,61E-04 0,01141566 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 2,61E-04 0,01121181 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 3,216E-04 0,013577 ! regulation of developmental growth GO:0048638 15 9 1,000 3,348E-04 0,01389011 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,348E-04 0,01365469 ! regulation of glycolysis GO:0006110 21 9 1,000 3,348E-04 0,01342711 ! keratinocyte proliferation GO:0043616 14 9 1,000 3,348E-04 0,01320699 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,348E-04 0,01299397 ! induction of an organ GO:0001759 14 9 1,000 3,348E-04 0,01278772 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 3,682E-04 0,01384177 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 3,93E-04 0,01454716 ! response to insulin stimulus GO:0032868 95 46 2,000 3,93E-04 0,01432675 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,177E-04 0,01500011 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,177E-04 0,01477952 ! regulation of smoothened signaling pathway GO:0008589 23 10 1,000 4,177E-04 0,01456533 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 4,177E-04 0,01435725 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 4,177E-04 0,01415504 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 4,177E-04 0,01395844 ! regulation of cell projection organization GO:0031344 121 50 2,000 5,029E-04 0,01657587 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 5,095E-04 0,01656585 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 5,095E-04 0,01634497 ! regulation of intracellular pH GO:0051453 19 11 1,000 5,095E-04 0,0161299 ! DNA methylation GO:0006306 19 11 1,000 5,095E-04 0,01592042 GO:0006305|DNA alkylation, ! developmental induction GO:0031128 19 11 1,000 5,095E-04 0,01571632 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 5,095E-04 0,01551738 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 6,102E-04 0,01835112 ! virus-host interaction GO:0019048 29 12 1,000 6,102E-04 0,01812457 ! regulation of B cell proliferation GO:0030888 20 12 1,000 6,102E-04 0,01790353 ! entry into host cell GO:0030260 32 12 1,000 6,102E-04 0,01768783 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 6,102E-04 0,01747726 ! peptidyl-lysine modification GO:0018205 21 12 1,000 6,102E-04 0,01727165 ! regulation of DNA replication GO:0006275 101 56 2,000 7,018E-04 0,01963482 ! cell-cell junction assembly GO:0007043 27 13 1,000 7,197E-04 0,01990262 ! response to X-ray GO:0010165 25 13 1,000 7,197E-04 0,01967646 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 7,197E-04 0,01945537 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 7,197E-04 0,0192392 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 7,197E-04 0,01902778 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 7,197E-04 0,01882096 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 7,392E-04 0,01912298 ! positive regulation of cell migration GO:0030335 126 57 2,000 7,392E-04 0,01891954 ! establishment of organelle localization GO:0051656 109 59 2,000 8,176E-04 0,02070658 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 8,379E-04 0,02100059 ! response to gamma radiation GO:0010332 28 14 1,000 8,379E-04 0,02078409 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 8,379E-04 0,02057201 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 8,587E-04 0,02086919 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 8,587E-04 0,0206605 ! regulation of protein complex assembly GO:0043254 117 61 2,000 9,011E-04 0,02146613 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 9,011E-04 0,02125567 ! viral reproductive process GO:0022415 126 62 2,000 9,448E-04 0,02207039 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 9,649E-04 0,02232256 ! G1/S transition checkpoint GO:0031575 40 15 1,000 9,649E-04 0,02210996 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 9,899E-04 0,02246795 ! positive regulation of cell motion GO:0051272 146 64 2,000 1,036E-03 0,02330067 ! myeloid cell differentiation GO:0030099 111 65 2,000 1,084E-03 0,02414811 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,101E-03 0,02429235 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,101E-03 0,02407151 ! cell projection assembly GO:0030031 120 66 2,000 1,133E-03 0,02455955 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 1,184E-03 0,02542455 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,184E-03 0,02519956 ! lung development GO:0030324 144 67 2,000 1,184E-03 0,02497851 ! negative regulation of kinase activity GO:0033673 131 68 2,000 1,235E-03 0,02584654 ! viral reproduction GO:0016032 134 68 2,000 1,235E-03 0,02562372 ! cell cycle checkpoint GO:0000075 137 69 2,000 1,289E-03 0,02650043 ! negative regulation of cell size GO:0045792 134 69 2,000 1,289E-03 0,02627585 ! respiratory tube development GO:0030323 150 70 2,000 1,343E-03 0,02716118 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,398E-03 0,02802072 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,398E-03 0,02778914 ! negative regulation of transferase activity GO:0051348 140 72 2,000 1,457E-03 0,02873665 ! respiratory system development GO:0060541 153 72 2,000 1,457E-03 0,02850302 ! lipid phosphorylation GO:0046834 35 19 1,000 1,559E-03 0,03024621 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,559E-03 0,03000424 ! pigmentation during development GO:0048066 41 19 1,000 1,559E-03 0,02976611 ! cell-cell junction organization GO:0045216 35 19 1,000 1,559E-03 0,02953173 ! organelle localization GO:0051640 136 74 2,000 1,577E-03 0,02963823 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,729E-03 0,03223948 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,729E-03 0,03199149 ! cellular response to starvation GO:0009267 33 20 1,000 1,729E-03 0,03174728 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,729E-03 0,03150677 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,729E-03 0,03126987 ! cell aging GO:0007569 44 21 1,000 1,907E-03 0,0342347 ! DNA modification GO:0006304 34 21 1,000 1,907E-03 0,03398111 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 1,907E-03 0,03373125 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 2,093E-03 0,03675966 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 2,093E-03 0,03649328 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,093E-03 0,03623074 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 2,093E-03 0,03597195 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 2,093E-03 0,03571683 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,093E-03 0,0354653 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 2,116E-03 0,03560452 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,288E-03 0,03822666 ! sex determination GO:0007530 47 23 1,000 2,288E-03 0,03796302 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,288E-03 0,037703 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 2,491E-03 0,04076885 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,491E-03 0,04049339 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,491E-03 0,04022162 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 2,491E-03 0,03995347 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,491E-03 0,03968888 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,491E-03 0,03942777 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,702E-03 0,04249083 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 2,702E-03 0,04221491 ! negative regulation of DNA replication GO:0008156 42 25 1,000 2,702E-03 0,04194256 ! response to starvation GO:0042594 42 25 1,000 2,702E-03 0,0416737 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,702E-03 0,04140826 ! negative regulation of cell development GO:0010721 73 25 1,000 2,702E-03 0,04114618 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 2,702E-03 0,0408874 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,702E-03 0,04063185 ! initiation of viral infection GO:0019059 57 26 1,000 2,921E-03 0,04365678 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,921E-03 0,04338729 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 2,921E-03 0,04312111 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 3,149E-03 0,0461941 ! protein amino acid acylation GO:0043543 55 27 1,000 3,149E-03 0,04591414 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,149E-03 0,04563755 ! base-excision repair GO:0006284 41 27 1,000 3,149E-03 0,04536427 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,384E-03 0,04846576 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 3,408E-03 0,04851477 ! regulation of pH GO:0006885 43 29 1,000 3,628E-03 0,05134038 ! complement activation, classical pathway GO:0006958 48 29 1,000 3,628E-03 0,05104014 ! cell cycle arrest GO:0007050 213 100 2,000 3,713E-03 0,05193245 ! cell junction assembly GO:0034329 78 30 1,000 3,879E-03 0,05394544 ! regulation of B cell activation GO:0050864 50 30 1,000 3,879E-03 0,05363541 ! cholesterol homeostasis GO:0042632 53 31 1,000 4,138E-03 0,05689268 GO:0055092|sterol homeostasis, ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 4,138E-03 0,05656942 ! response to ionizing radiation GO:0010212 65 32 1,000 4,405E-03 0,05987975 ! positive regulation of catabolic process GO:0009896 64 32 1,000 4,405E-03 0,05954334 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 4,68E-03 0,06290464 ! cell fate specification GO:0001708 52 33 1,000 4,68E-03 0,06255517 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 5,253E-03 0,06982345 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 5,253E-03 0,06943981 ! calcium-mediated signaling GO:0019722 62 35 1,000 5,253E-03 0,06906036 ! cytokine production GO:0001816 59 35 1,000 5,253E-03 0,06868503 ! neural tube formation GO:0001841 67 35 1,000 5,253E-03 0,06831376 ! cell junction organization GO:0034330 86 36 1,000 5,551E-03 0,0717995 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 5,856E-03 0,07534553 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 6,169E-03 0,07895027 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 6,169E-03 0,07853255 ! carbohydrate homeostasis GO:0033500 53 38 1,000 6,169E-03 0,07811922 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 1,000 6,169E-03 0,07771022 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 6,169E-03 0,07730548 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 6,169E-03 0,07690493 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 6,489E-03 0,08048299 ! segmentation GO:0035282 67 39 1,000 6,489E-03 0,08007026 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 7,153E-03 0,08780293 ! T cell differentiation GO:0030217 81 41 1,000 7,153E-03 0,08735723 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 7,153E-03 0,08691603 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 7,495E-03 0,09062194 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 7,495E-03 0,09016883 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 7,845E-03 0,09390902 ! neural tube development GO:0021915 77 43 1,000 7,845E-03 0,09344412 ! double-strand break repair GO:0006302 81 44 1,000 8,202E-03 0,09721722 ! biopolymer methylation GO:0043414 84 44 1,000 8,202E-03 0,09674066 ! B cell differentiation GO:0030183 107 44 1,000 8,202E-03 0,09626876 ! cell growth GO:0016049 84 45 1,000 8,567E-03 0,1000573 ! pigmentation GO:0043473 100 46 1,000 8,938E-03 0,10389238 ! positive regulation of defense response GO:0031349 76 47 1,000 9,317E-03 0,1077728 ! positive regulation of DNA binding GO:0043388 73 47 1,000 9,317E-03 0,10725714 ! methylation GO:0032259 90 47 1,000 9,317E-03 0,1067464 ! mitochondrial transport GO:0006839 82 48 1,000 9,703E-03 0,11063863 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 9,703E-03 0,11011675 ! activation of caspase activity GO:0006919 84 48 1,000 9,703E-03 0,10959977 ! regulation of inflammatory response GO:0050727 75 48 1,000 9,703E-03 0,10908762 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 9,703E-03 0,10858023 ! positive regulation of cell cycle GO:0045787 89 48 1,000 9,703E-03 0,10807755 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,01009544 0,1119338 GO:0019724|B cell mediated immunity, ! histone modification GO:0016570 91 50 1,000 0,01049513 0,11583158 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01049513 0,11530267 ! positive regulation of binding GO:0051099 78 51 1,000 0,01090174 0,11922541 ! viral infectious cycle GO:0019058 99 51 1,000 0,01090174 0,11868593 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,01090174 0,1181513 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 0,01090174 0,11762148 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,01090174 0,11709638 ! positive regulation of growth GO:0045927 90 52 1,000 0,01131523 0,12099752 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01131523 0,12046213 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01173555 0,12438647 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01216265 0,128348 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,0125965 0,13234577 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,0125965 0,13177035 ! aging GO:0007568 103 55 1,000 0,0125965 0,13119991 ! heart morphogenesis GO:0003007 97 55 1,000 0,0125965 0,1306344 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,0125965 0,13007374 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01303704 0,13404756 ! lipid modification GO:0030258 97 57 1,000 0,01348424 0,13805566 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01348424 0,13747068 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01393804 0,1414976 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,01439841 0,14555703 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01534574 0,1544847 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01534574 0,15384101 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01534574 0,15320267 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01534574 0,1525696 ! neuron fate determination GO:0048664 7 5 0,000 0,01534574 0,15194174 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01534574 0,15131903 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01534574 0,1507014 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01534574 0,15008879 ! polyol transport GO:0015791 12 5 0,000 0,01534574 0,14948115 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01534574 0,1488784 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01534574 0,14828049 ! response to superoxide GO:0000303 10 5 0,000 0,01534574 0,14768737 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01534574 0,14709898 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01534574 0,14651525 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01534574 0,14593614 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01534574 0,14536159 ! female meiosis GO:0007143 7 5 0,000 0,01534574 0,14479154 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01534574 0,14422595 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01534574 0,14366476 ! cobalt ion transport GO:0006824 11 5 0,000 0,01534574 0,14310792 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01534574 0,14255538 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01534574 0,14200709 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01534574 0,141463 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01534574 0,14092306 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01534574 0,14038724 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01534574 0,13985547 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01534574 0,13932771 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01534574 0,13880392 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01534574 0,13828406 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01534574 0,13776807 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01534574 0,13725592 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01534574 0,13674757 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01534574 0,13624296 ! negative chemotaxis GO:0050919 14 5 0,000 0,01534574 0,13574207 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01534574 0,13524485 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01534574 0,13475125 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01534574 0,13426125 ! behavioral response to pain GO:0048266 9 5 0,000 0,01534574 0,13377479 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01534574 0,13329185 ! Notch receptor processing GO:0007220 8 5 0,000 0,01534574 0,13281238 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01534574 0,13233635 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01534574 0,13186372 ! micturition GO:0060073 9 5 0,000 0,01534574 0,13139446 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01534574 0,13092852 ! copulation GO:0007620 9 5 0,000 0,01534574 0,13046588 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01534574 0,13000649 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01534574 0,12955033 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01534574 0,12909735 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01534574 0,12864754 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01534574 0,12820084 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01534574 0,12775724 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01534574 0,1273167 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01534574 0,12687919 ! grooming behavior GO:0007625 6 5 0,000 0,01534574 0,12644467 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01534574 0,12601312 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01534574 0,1255845 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01534574 0,12515879 ! response to protozoan GO:0001562 10 5 0,000 0,01534574 0,12473596 ! lymph vessel development GO:0001945 10 5 0,000 0,01534574 0,12431597 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01534574 0,1238988 ! endochondral ossification GO:0001958 16 5 0,000 0,01534574 0,12348442 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01534574 0,12307281 ! parathyroid gland development GO:0060017 13 5 0,000 0,01534574 0,12266393 ! anagen GO:0042640 6 5 0,000 0,01534574 0,12225776 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01534574 0,12185427 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01534574 0,12145343 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01534574 0,12105522 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01534574 0,12065962 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01534574 0,12026659 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01534574 0,11987611 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01534574 0,11948816 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01534574 0,11910272 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01534574 0,11871975 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01534574 0,11833924 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01534574 0,11796116 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01534574 0,11758549 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01534574 0,1172122 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01534574 0,11684128 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01534574 0,11647269 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01534574 0,11610642 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01534574 0,11574245 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01534574 0,11538076 ! histidine catabolic process GO:0006548 6 5 0,000 0,01534574 0,11502132 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01534574 0,11466411 ! microvillus organization GO:0032528 7 5 0,000 0,01534574 0,11430911 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01534574 0,11395631 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01534574 0,11360567 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01534574 0,11325719 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01534574 0,11291083 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01534574 0,11256659 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01534574 0,11222445 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01534574 0,11188437 ! polyol catabolic process GO:0046174 7 5 0,000 0,01534574 0,11154635 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01534574 0,11121037 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01534574 0,11087641 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01534574 0,11054444 ! muscle cell migration GO:0014812 8 5 0,000 0,01534574 0,11021446 ! mitochondrial fission GO:0000266 8 5 0,000 0,01534574 0,10988644 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01534574 0,10956036 ! mRNA transcription GO:0009299 9 5 0,000 0,01534574 0,10923622 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01534574 0,10891399 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01534574 0,10859366 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01534574 0,1082752 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01534574 0,1079586 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01534574 0,10764386 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01534574 0,10733094 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01534574 0,10701983 ! response to food GO:0032094 6 5 0,000 0,01534574 0,10671053 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01534574 0,10640301 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01534574 0,10609725 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01534574 0,10579325 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01534574 0,10549098 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01534574 0,10519044 ! forebrain neuron development GO:0021884 13 5 0,000 0,01534574 0,1048916 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01534574 0,10459446 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01534574 0,10429899 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01534574 0,10400519 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01534574 0,10371304 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01534574 0,10342253 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01534574 0,10313364 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01534574 0,10284636 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01534574 0,10256067 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01534574 0,10227657 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01534574 0,10199404 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01534574 0,10171307 ! basic amino acid transport GO:0015802 11 5 0,000 0,01534574 0,10143363 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01534574 0,10115573 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01534574 0,10087935 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01534574 0,10060448 ! depyrimidination GO:0045008 10 5 0,000 0,01534574 0,10033109 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01534574 0,10005919 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01534574 0,09978876 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01534574 0,09951979 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01534574 0,09925227 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01534574 0,09898617 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01534574 0,09872151 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01534574 0,09845825 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01534574 0,09819639 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01534574 0,09793592 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01534574 0,09767683 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01534574 0,09741911 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01534574 0,09716274 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01534574 0,09690772 ! response to arsenic GO:0046685 10 5 0,000 0,01534574 0,09665404 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01534574 0,09640168 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01534574 0,09615063 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01534574 0,09590089 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01534574 0,09565244 ! response to cadmium ion GO:0046686 7 5 0,000 0,01534574 0,09540528 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01534574 0,09515939 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01534574 0,09491476 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01534574 0,09467139 ! decidualization GO:0046697 11 5 0,000 0,01534574 0,09442927 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01534574 0,09418837 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01534574 0,09394871 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01534574 0,09371026 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01534574 0,09347302 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01534574 0,09323698 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01534574 0,09300212 ! neural tube patterning GO:0021532 7 5 0,000 0,01534574 0,09276845 ! embryonic cleavage GO:0040016 6 5 0,000 0,01534574 0,09253595 ! peroxisome fission GO:0016559 5 5 0,000 0,01534574 0,09230461 ! histone demethylation GO:0016577 10 5 0,000 0,01534574 0,09207442 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01534574 0,09184538 ! mitotic recombination GO:0006312 9 5 0,000 0,01534574 0,09161748 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01534574 0,0913907 ! metaphase plate congression GO:0051310 7 5 0,000 0,01534574 0,09116504 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01534574 0,0909405 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01534574 0,09071706 ! enteric nervous system development GO:0048484 8 5 0,000 0,01534574 0,09049471 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01534574 0,09027345 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01534574 0,09005328 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01534574 0,08983417 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01534574 0,08961612 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01534574 0,08939914 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01534574 0,0891832 ! plasminogen activation GO:0031639 5 5 0,000 0,01534574 0,0889683 ! B cell homeostasis GO:0001782 13 5 0,000 0,01534574 0,08875443 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01534574 0,08854159 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01534574 0,08832977 ! metaphase GO:0051323 8 5 0,000 0,01534574 0,08811896 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01534574 0,08790915 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01534574 0,08770034 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01534574 0,08749252 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01534574 0,08728568 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01534574 0,08707982 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01534574 0,08687492 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01534574 0,08667099 ! response to redox state GO:0051775 5 5 0,000 0,01534574 0,08646802 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01534574 0,08626599 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01534574 0,0860649 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01534574 0,08586475 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01534574 0,08566553 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01534574 0,08546723 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01534574 0,08526985 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01534574 0,08507337 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01534574 0,0848778 ! striatum development GO:0021756 9 5 0,000 0,01534574 0,08468313 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01534574 0,08448934 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01534574 0,08429644 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01534574 0,08410443 ! glial cell migration GO:0008347 11 5 0,000 0,01534574 0,08391328 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01534574 0,083723 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01534574 0,08353358 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01534574 0,08334502 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01534574 0,0831573 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01534574 0,08297043 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01534574 0,0827844 ! neuroprotection GO:0043526 6 5 0,000 0,01534574 0,0825992 ! neural plate development GO:0001840 8 5 0,000 0,01534574 0,08241483 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01534574 0,08223128 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01534574 0,08204854 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01534574 0,08186661 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01534574 0,08168549 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01534574 0,08150517 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01534574 0,08132565 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01534574 0,08114691 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01534574 0,08096895 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01534574 0,08079178 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01534574 0,08061538 ! spindle assembly GO:0051225 6 5 0,000 0,01534574 0,08043974 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01534574 0,08026488 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01534574 0,08009077 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01534574 0,07991741 ! drug metabolic process GO:0017144 6 5 0,000 0,01534574 0,0797448 ! stem cell division GO:0017145 11 5 0,000 0,01534574 0,07957294 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01534574 0,07940181 ! organ regeneration GO:0031100 7 5 0,000 0,01534574 0,07923142 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01534574 0,07906176 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01534574 0,07889283 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01534574 0,07872461 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,01679716 0,08598719 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,017296 0,0883528 GO:0035113|embryonic appendage morphogenesis, ! activation of MAPK activity GO:0000187 115 67 1,000 0,0183124 0,09334668 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,0183124 0,09314933 ! adaptive immune response GO:0002250 119 67 1,000 0,0183124 0,09295281 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,0183124 0,09275712 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01838681 0,09293838 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01838681 0,09274354 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01838681 0,09254952 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01838681 0,0923563 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01838681 0,09216389 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01838681 0,09197228 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01838681 0,09178147 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01838681 0,09159145 ! sleep GO:0030431 13 6 0,000 0,01838681 0,09140221 ! response to oxygen radical GO:0000305 11 6 0,000 0,01838681 0,09121375 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01838681 0,09102607 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01838681 0,09083916 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01838681 0,09065301 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01838681 0,09046763 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01838681 0,090283 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01838681 0,09009912 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01838681 0,08991599 ! forebrain regionalization GO:0021871 8 6 0,000 0,01838681 0,08973361 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01838681 0,08955196 ! male meiosis GO:0007140 7 6 0,000 0,01838681 0,08937105 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01838681 0,08919087 ! response to zinc ion GO:0010043 9 6 0,000 0,01838681 0,08901141 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01838681 0,08883267 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01838681 0,08865465 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01838681 0,08847734 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01838681 0,08830074 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01838681 0,08812484 ! malate metabolic process GO:0006108 11 6 0,000 0,01838681 0,08794964 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01838681 0,08777514 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01838681 0,08760132 ! protein refolding GO:0042026 15 6 0,000 0,01838681 0,0874282 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01838681 0,08725576 ! opsonization GO:0008228 8 6 0,000 0,01838681 0,08708399 ! mating behavior GO:0007617 7 6 0,000 0,01838681 0,08691291 ! neuron remodeling GO:0016322 15 6 0,000 0,01838681 0,08674249 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01838681 0,08657274 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01838681 0,08640365 ! equilibrioception GO:0050957 14 6 0,000 0,01838681 0,08623522 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01838681 0,08606745 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01838681 0,08590033 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01838681 0,08573385 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01838681 0,08556803 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01838681 0,08540284 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01838681 0,08523828 ! toxin metabolic process GO:0009404 11 6 0,000 0,01838681 0,08507436 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01838681 0,08491107 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01838681 0,08474841 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01838681 0,08458637 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01838681 0,08442494 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01838681 0,08426413 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01838681 0,08410393 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01838681 0,08394434 ! thymic T cell selection GO:0045061 12 6 0,000 0,01838681 0,08378536 ! protein lipoylation GO:0009249 10 6 0,000 0,01838681 0,08362697 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01838681 0,08346919 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01838681 0,08331199 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01838681 0,08315539 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01838681 0,08299938 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01838681 0,08284395 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01838681 0,0826891 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01838681 0,08253483 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01838681 0,08238113 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01838681 0,08222801 ! hyperosmotic response GO:0006972 9 6 0,000 0,01838681 0,08207545 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01838681 0,08192346 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01838681 0,08177203 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01838681 0,08162116 ! urea metabolic process GO:0019627 7 6 0,000 0,01838681 0,08147085 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01838681 0,08132108 ! neutrophil activation GO:0042119 8 6 0,000 0,01838681 0,08117187 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01838681 0,0810232 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01838681 0,08087508 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01838681 0,0807275 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01838681 0,08058045 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01838681 0,08043394 ! neuron apoptosis GO:0051402 9 6 0,000 0,01838681 0,08028797 ! nucleoside salvage GO:0043174 9 6 0,000 0,01838681 0,08014252 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01838681 0,07999759 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01838681 0,07985319 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01838681 0,07970931 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01838681 0,07956595 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01838681 0,0794231 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01838681 0,07928077 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01838681 0,07913894 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01838681 0,07899762 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01838681 0,07885681 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01838681 0,07871649 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01838681 0,07857668 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01838681 0,07843736 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01838681 0,07829853 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01838681 0,07816019 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01838681 0,07802234 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01838681 0,07788498 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01838681 0,0777481 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01838681 0,0776117 ! neural nucleus development GO:0048857 14 6 0,000 0,01838681 0,07747578 ! response to UV-C GO:0010225 11 6 0,000 0,01838681 0,07734033 ! astrocyte development GO:0014002 15 6 0,000 0,01838681 0,07720536 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01838681 0,07707085 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01838681 0,07693682 ! interaction with symbiont GO:0051702 13 6 0,000 0,01838681 0,07680324 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01838681 0,07667014 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01838681 0,07653749 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01838681 0,0764053 ! response to copper ion GO:0046688 10 6 0,000 0,01838681 0,07627357 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01838681 0,07614229 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01838681 0,07601146 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01838681 0,07588108 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01838681 0,07575115 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01838681 0,07562166 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01838681 0,07549261 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01838681 0,075364 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01838681 0,07523583 ! hair follicle maturation GO:0048820 7 6 0,000 0,01838681 0,0751081 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01838681 0,07498079 ! Schwann cell development GO:0014044 15 6 0,000 0,01838681 0,07485392 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01838681 0,07472748 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01838681 0,07460147 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01838681 0,07447587 ! subpallium development GO:0021544 10 6 0,000 0,01838681 0,0743507 ! histone ubiquitination GO:0016574 8 6 0,000 0,01838681 0,07422595 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01838681 0,07410162 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01838681 0,07397771 ! G2 phase GO:0051319 16 6 0,000 0,01838681 0,07385421 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01838681 0,07373112 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01838681 0,07360843 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01838681 0,07348616 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01838681 0,07336429 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01838681 0,07324283 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01838681 0,07312177 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01838681 0,0730011 ! receptor internalization GO:0031623 10 6 0,000 0,01838681 0,07288084 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01838681 0,07276097 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01838681 0,07264149 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01838681 0,07252241 ! protein deubiquitination GO:0016579 14 6 0,000 0,01838681 0,07240371 ! protein destabilization GO:0031648 9 6 0,000 0,01838681 0,07228541 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01838681 0,07216749 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01838681 0,07204995 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01838681 0,0719328 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01838681 0,07181602 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01838681 0,07169963 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01838681 0,07158361 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01838681 0,07146796 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01838681 0,07135269 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01838681 0,07123779 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01838681 0,07112326 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01838681 0,0710091 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01838681 0,0708953 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01838681 0,07078187 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01838681 0,0706688 ! catecholamine transport GO:0051937 9 6 0,000 0,01838681 0,07055609 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01838681 0,07044374 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01838681 0,07033175 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01838681 0,07022011 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01838681 0,07010883 ! maternal placenta development GO:0001893 12 6 0,000 0,01838681 0,06999789 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01838681 0,06988731 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01838681 0,06977708 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01838681 0,0696672 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01838681 0,06955766 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01838681 0,06944846 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01838681 0,06933961 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01838681 0,06923109 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01882988 0,07078859 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,01882988 0,07067816 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,01882988 0,07056807 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,0193535 0,07241761 ! appendage morphogenesis GO:0035107 135 70 1,000 0,01988321 0,07428417 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 0,02041897 0,07616751 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 1,000 0,02041897 0,0760496 ! B cell activation GO:0042113 160 71 1,000 0,02041897 0,07593206 ! acute inflammatory response GO:0002526 113 72 1,000 0,02096074 0,07782644 ! regulation of caspase activity GO:0043281 122 72 1,000 0,02096074 0,07770652 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02096074 0,07758697 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,02096074 0,07746779 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,02096074 0,07734898 ! tRNA transcription GO:0009304 14 7 0,000 0,0214186 0,07891752 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,0214186 0,07879685 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,0214186 0,07867655 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0214186 0,07855662 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,0214186 0,07843705 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,0214186 0,07831784 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0214186 0,078199 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,0214186 0,07808051 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0214186 0,07796239 ! prostate gland development GO:0030850 13 7 0,000 0,0214186 0,07784462 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,0214186 0,07772721 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0214186 0,07761015 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0214186 0,07749344 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,0214186 0,07737709 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0214186 0,07726108 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,0214186 0,07714542 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,0214186 0,0770301 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,0214186 0,07691513 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0214186 0,07680051 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,0214186 0,07668622 ! glycolipid transport GO:0046836 10 7 0,000 0,0214186 0,07657227 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0214186 0,07645866 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,0214186 0,07634539 ! neuron adhesion GO:0007158 12 7 0,000 0,0214186 0,07623246 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0214186 0,07611985 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,0214186 0,07600758 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0214186 0,07589564 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,0214186 0,07578403 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,0214186 0,07567275 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,0214186 0,07556179 ! mRNA stabilization GO:0048255 18 7 0,000 0,0214186 0,07545116 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,0214186 0,07534085 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,0214186 0,07523086 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,0214186 0,07512119 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,0214186 0,07501185 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0214186 0,07490282 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,0214186 0,07479411 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0214186 0,07468571 ! lipoprotein transport GO:0042953 14 7 0,000 0,0214186 0,07457763 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0214186 0,07446985 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0214186 0,07436239 ! rhythmic behavior GO:0007622 15 7 0,000 0,0214186 0,07425524 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,0214186 0,0741484 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,0214186 0,07404187 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,0214186 0,07393564 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0214186 0,07382971 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,0214186 0,07372409 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0214186 0,07361877 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,0214186 0,07351375 ! mechanosensory behavior GO:0007638 14 7 0,000 0,0214186 0,07340903 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,0214186 0,07330461 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0214186 0,07320048 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,0214186 0,07309665 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0214186 0,07299312 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0214186 0,07288987 ! spinal cord patterning GO:0021511 13 7 0,000 0,0214186 0,07278692 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,0214186 0,07268426 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0214186 0,07258189 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,0214186 0,0724798 ! adrenal gland development GO:0030325 17 7 0,000 0,0214186 0,07237801 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,0214186 0,07227649 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,0214186 0,07217527 ! ovulation GO:0030728 9 7 0,000 0,0214186 0,07207432 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,0214186 0,07197366 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,0214186 0,07187328 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,0214186 0,07177317 ! microtubule nucleation GO:0007020 20 7 0,000 0,0214186 0,07167335 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0214186 0,07157381 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0214186 0,07147453 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,0214186 0,07137554 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,0214186 0,07127682 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,0214186 0,07117837 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0214186 0,07108019 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0214186 0,07098229 ! galactose metabolic process GO:0006012 13 7 0,000 0,0214186 0,07088465 ! vesicle fusion GO:0006906 17 7 0,000 0,0214186 0,07078728 ! response to dietary excess GO:0002021 8 7 0,000 0,0214186 0,07069018 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0214186 0,07059334 ! intracellular pH reduction GO:0051452 11 7 0,000 0,0214186 0,07049677 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0214186 0,07040046 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,0214186 0,07030442 ! organ growth GO:0035265 15 7 0,000 0,0214186 0,07020864 ! purine salvage GO:0043101 10 7 0,000 0,0214186 0,07011312 ! nucleoside transport GO:0015858 8 7 0,000 0,0214186 0,07001785 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,0214186 0,06992285 ! parturition GO:0007567 14 7 0,000 0,0214186 0,0698281 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,0214186 0,06973361 ! rRNA modification GO:0000154 14 7 0,000 0,0214186 0,06963938 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,0214186 0,0695454 ! spindle checkpoint GO:0031577 15 7 0,000 0,0214186 0,06945167 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,0214186 0,0693582 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,0214186 0,06926497 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0214186 0,069172 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0214186 0,06907928 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,0214186 0,0689868 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,0214186 0,06889457 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0214186 0,06880259 ! fibrinolysis GO:0042730 10 7 0,000 0,0214186 0,06871085 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,0214186 0,06861936 ! eating behavior GO:0042755 7 7 0,000 0,0214186 0,06852811 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0214186 0,0684371 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,0214186 0,06834634 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,0214186 0,06825581 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0214186 0,06816553 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,0214186 0,06807548 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0214186 0,06798567 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,0214186 0,0678961 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,0214186 0,06780676 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,0214186 0,06771766 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,0214186 0,06762879 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0214186 0,06754016 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,0214186 0,06745175 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0214186 0,06736358 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0214186 0,06727564 ! regulation of meiosis GO:0040020 12 7 0,000 0,0214186 0,06718793 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,0214186 0,06710044 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,0214186 0,06701319 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0214186 0,06692616 ! oxygen homeostasis GO:0032364 12 7 0,000 0,0214186 0,06683935 ! transcription termination GO:0006353 13 7 0,000 0,0214186 0,06675277 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0214186 0,06666642 ! anaphase GO:0051322 17 7 0,000 0,0214186 0,06658028 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,0214186 0,06649437 ! axonal fasciculation GO:0007413 18 7 0,000 0,0214186 0,06640869 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,0214186 0,06632322 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,0214186 0,06623797 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,0214186 0,06615294 ! diuresis GO:0030146 12 7 0,000 0,0214186 0,06606813 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0214186 0,06598353 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0214186 0,06589916 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0214186 0,06581499 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,0214186 0,06573105 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,0214186 0,06564731 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0214186 0,06556379 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0214186 0,06548048 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0214186 0,06539739 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0214186 0,0653145 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,0214186 0,06523182 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0214186 0,06514935 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,0214186 0,0650671 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0214186 0,06498504 ! lymph node development GO:0048535 10 7 0,000 0,0214186 0,0649032 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,0214186 0,06482156 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0214186 0,06474013 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,0214186 0,0646589 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,0214186 0,06457787 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,0214186 0,06449705 ! adult feeding behavior GO:0008343 9 7 0,000 0,0214186 0,06441642 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,0214186 0,064336 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,0214186 0,06425579 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0214186 0,06417577 ! muscle adaptation GO:0043500 14 7 0,000 0,0214186 0,06409594 ! embryonic heart tube development GO:0035050 10 7 0,000 0,0214186 0,06401632 ! retina homeostasis GO:0001895 12 7 0,000 0,0214186 0,0639369 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,0214186 0,06385767 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,0214186 0,06377864 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,0214186 0,0636998 ! protein prenylation GO:0018342 18 7 0,000 0,0214186 0,06362116 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,0214186 0,06354271 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,0214186 0,06346446 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0214186 0,0633864 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,02206213 0,06521067 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,02206213 0,06513065 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,02206213 0,06505084 ! eye development GO:0001654 143 74 1,000 0,02206213 0,06497121 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02262167 0,06653758 ! regulation of catabolic process GO:0009894 161 76 1,000 0,02318706 0,06811729 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,02375825 0,06971017 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02375825 0,06962527 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,0243352 0,07122931 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02444111 0,0714524 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02444111 0,07136568 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02444111 0,07127918 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02444111 0,07119288 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02444111 0,0711068 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02444111 0,07102092 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02444111 0,07093525 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02444111 0,07084979 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02444111 0,07076453 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02444111 0,07067947 ! meiotic prophase I GO:0007128 13 8 0,000 0,02444111 0,07059462 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02444111 0,07050998 ! oligopeptide transport GO:0006857 15 8 0,000 0,02444111 0,07042554 ! UTP metabolic process GO:0046051 8 8 0,000 0,02444111 0,07034129 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02444111 0,07025725 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02444111 0,07017342 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02444111 0,07008978 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02444111 0,07000634 ! succinate metabolic process GO:0006105 14 8 0,000 0,02444111 0,06992309 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02444111 0,06984005 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02444111 0,0697572 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02444111 0,06967455 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02444111 0,0695921 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02444111 0,06950984 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02444111 0,06942777 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02444111 0,0693459 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02444111 0,06926422 ! reflex GO:0060004 16 8 0,000 0,02444111 0,06918273 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02444111 0,06910144 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02444111 0,06902033 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02444111 0,06893942 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02444111 0,06885869 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02444111 0,06877815 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02444111 0,06869781 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02444111 0,06861765 ! pigment granule organization GO:0048753 16 8 0,000 0,02444111 0,06853767 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02444111 0,06845788 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02444111 0,06837828 ! histidine metabolic process GO:0006547 16 8 0,000 0,02444111 0,06829886 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02444111 0,06821963 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02444111 0,06814058 ! glycine catabolic process GO:0006546 13 8 0,000 0,02444111 0,06806172 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02444111 0,06798303 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02444111 0,06790453 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02444111 0,06782621 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02444111 0,06774807 ! melanin metabolic process GO:0006582 15 8 0,000 0,02444111 0,06767011 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02444111 0,06759232 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02444111 0,06751472 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02444111 0,0674373 ! macrophage activation GO:0042116 12 8 0,000 0,02444111 0,06736005 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02444111 0,06728298 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02444111 0,06720608 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02444111 0,06712936 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02444111 0,06705282 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02444111 0,06697645 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02444111 0,06690025 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02444111 0,06682423 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02444111 0,06674838 ! osteoblast development GO:0002076 16 8 0,000 0,02444111 0,0666727 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02444111 0,06659719 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02444111 0,06652186 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02444111 0,06644669 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02444111 0,0663717 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02444111 0,06629687 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02444111 0,06622221 ! response to UV-B GO:0010224 16 8 0,000 0,02444111 0,06614772 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02444111 0,0660734 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02444111 0,06599924 ! intermediate filament organization GO:0045109 12 8 0,000 0,02444111 0,06592525 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02444111 0,06585142 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02444111 0,06577777 ! cellular extravasation GO:0045123 12 8 0,000 0,02444111 0,06570427 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02444111 0,06563094 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02444111 0,06555777 ! response to antibiotic GO:0046677 11 8 0,000 0,02444111 0,06548477 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02444111 0,06541193 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02444111 0,06533925 ! DNA topological change GO:0006265 12 8 0,000 0,02444111 0,06526673 ! response to tropane GO:0014073 15 8 0,000 0,02444111 0,06519437 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02444111 0,06512217 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02444111 0,06505014 ! melanosome transport GO:0032402 13 8 0,000 0,02444111 0,06497826 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02444111 0,06490654 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02444111 0,06483497 ! mast cell activation GO:0045576 14 8 0,000 0,02444111 0,06476357 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02444111 0,06469232 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02444111 0,06462123 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02444111 0,0645503 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02444111 0,06447952 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02444111 0,0644089 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02444111 0,06433843 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02444111 0,06426811 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02444111 0,06419795 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02444111 0,06412794 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02444111 0,06405809 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02444111 0,06398838 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02444111 0,06391883 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02444111 0,06384943 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02444111 0,06378018 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02444111 0,06371107 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02444111 0,06364212 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02444111 0,06357332 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02444111 0,06350467 ! hormone catabolic process GO:0042447 17 8 0,000 0,02444111 0,06343616 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02444111 0,0633678 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02444111 0,06329959 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02444111 0,06323153 ! ATP catabolic process GO:0006200 11 8 0,000 0,02444111 0,06316361 ! blastocyst growth GO:0001832 19 8 0,000 0,02444111 0,06309584 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02444111 0,06302821 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02444111 0,06296073 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02444111 0,06289339 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02444111 0,0628262 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02444111 0,06275915 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02444111 0,06269224 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02444111 0,06262548 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02444111 0,06255885 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02444111 0,06249237 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02444111 0,06242603 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02444111 0,06235983 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02444111 0,06229377 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02444111 0,06222785 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02444111 0,06216207 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02444111 0,06209643 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02444111 0,06203093 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02444111 0,06196557 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02491787 0,06310779 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,02491787 0,06304143 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,02491787 0,06297521 ! protein import into nucleus GO:0006606 158 80 1,000 0,02550623 0,06439453 ! T cell activation GO:0042110 168 81 1,000 0,02610023 0,06582511 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,02610023 0,06575618 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,02610023 0,0656874 ! nuclear import GO:0051170 161 81 1,000 0,02610023 0,06561876 ! response to oxygen levels GO:0070482 176 83 1,000 0,027305 0,06857602 ! axon extension GO:0048675 15 9 0,000 0,0274544 0,06887934 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0274544 0,06880759 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0274544 0,06873599 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,0274544 0,06866454 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0274544 0,06859323 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0274544 0,06852208 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,0274544 0,06845107 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,0274544 0,06838021 ! phosphate transport GO:0006817 19 9 0,000 0,0274544 0,0683095 ! reproductive behavior GO:0019098 19 9 0,000 0,0274544 0,06823893 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0274544 0,06816851 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,0274544 0,06809823 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0274544 0,0680281 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0274544 0,06795811 ! GTP metabolic process GO:0046039 9 9 0,000 0,0274544 0,06788827 ! RNA methylation GO:0001510 15 9 0,000 0,0274544 0,06781857 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0274544 0,06774901 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,0274544 0,06767959 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,0274544 0,06761032 ! artery development GO:0060840 24 9 0,000 0,0274544 0,06754119 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0274544 0,0674722 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0274544 0,06740335 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,0274544 0,06733464 ! chemosensory behavior GO:0007635 20 9 0,000 0,0274544 0,06726607 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0274544 0,06719764 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0274544 0,06712935 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,0274544 0,0670612 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0274544 0,06699319 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0274544 0,06692531 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,0274544 0,06685758 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0274544 0,06678997 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0274544 0,06672251 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0274544 0,06665518 ! protein targeting to ER GO:0045047 22 9 0,000 0,0274544 0,06658799 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0274544 0,06652093 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,0274544 0,06645401 ! T cell selection GO:0045058 23 9 0,000 0,0274544 0,06638722 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0274544 0,06632057 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0274544 0,06625405 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,0274544 0,06618766 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0274544 0,06612141 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0274544 0,06605528 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0274544 0,06598929 ! mannose metabolic process GO:0006013 13 9 0,000 0,0274544 0,06592344 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0274544 0,06585771 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0274544 0,06579212 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0274544 0,06572665 ! receptor clustering GO:0043113 18 9 0,000 0,0274544 0,06566132 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0274544 0,06559611 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0274544 0,06553104 ! ruffle organization GO:0031529 15 9 0,000 0,0274544 0,06546609 ! retinol metabolic process GO:0042572 18 9 0,000 0,0274544 0,06540127 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0274544 0,06533658 ! behavioral fear response GO:0001662 22 9 0,000 0,0274544 0,06527202 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0274544 0,06520759 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0274544 0,06514328 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0274544 0,0650791 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,0274544 0,06501504 ! oligodendrocyte development GO:0014003 10 9 0,000 0,0274544 0,06495112 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,0274544 0,06488731 ! segment specification GO:0007379 13 9 0,000 0,0274544 0,06482364 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0274544 0,06476008 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0274544 0,06469665 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0274544 0,06463335 ! response to amine stimulus GO:0014075 13 9 0,000 0,0274544 0,06457017 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0274544 0,06450711 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0274544 0,06444418 ! erythrocyte development GO:0048821 15 9 0,000 0,0274544 0,06438137 ! gas homeostasis GO:0033483 16 9 0,000 0,0274544 0,06431868 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0274544 0,06425611 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,0274544 0,06419367 ! renal water homeostasis GO:0003091 14 9 0,000 0,0274544 0,06413134 ! postreplication repair GO:0006301 22 9 0,000 0,0274544 0,06406914 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0274544 0,06400706 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0274544 0,0639451 ! icosanoid secretion GO:0032309 15 9 0,000 0,0274544 0,06388325 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0274544 0,06382153 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0274544 0,06375993 ! regulation of cell division GO:0051302 15 9 0,000 0,0274544 0,06369844 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0274544 0,06363708 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0274544 0,06357583 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0274544 0,0635147 ! sterol catabolic process GO:0016127 11 9 0,000 0,0274544 0,06345368 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0274544 0,06339279 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0274544 0,06333201 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,0274544 0,06327135 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,0274544 0,0632108 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,0274544 0,06315037 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,0274544 0,06309005 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0274544 0,06302985 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0274544 0,06296977 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0274544 0,06290979 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0274544 0,06284994 ! purine base metabolic process GO:0006144 21 9 0,000 0,0274544 0,06279019 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,0274544 0,06273056 ! pigment granule transport GO:0051904 17 9 0,000 0,0274544 0,06267105 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0274544 0,06261164 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,0274544 0,06255235 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0274544 0,06249317 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0274544 0,06243411 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0274544 0,06237515 ! mitochondrion localization GO:0051646 15 9 0,000 0,0274544 0,06231631 ! regulation of ligase activity GO:0051340 142 84 1,000 0,02791569 0,06330362 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,02853186 0,06463998 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,02853186 0,06457917 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 0,02915348 0,06592413 ! mitochondrion organization GO:0007005 148 86 1,000 0,02915348 0,06586223 ! protein localization in nucleus GO:0034504 176 87 1,000 0,02978051 0,06721567 ! regulation of DNA binding GO:0051101 155 88 1,000 0,03041291 0,06857868 ! gland development GO:0048732 206 88 1,000 0,03041291 0,06851447 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03045848 0,06855294 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03045848 0,06848887 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03045848 0,06842492 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03045848 0,06836109 ! synapsis GO:0007129 13 10 0,000 0,03045848 0,06829738 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03045848 0,06823379 ! N-glycan processing GO:0006491 20 10 0,000 0,03045848 0,06817032 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03045848 0,06810696 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03045848 0,06804373 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03045848 0,06798061 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03045848 0,0679176 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03045848 0,06785472 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,03045848 0,06779195 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03045848 0,06772929 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03045848 0,06766675 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03045848 0,06760433 ! androgen metabolic process GO:0008209 17 10 0,000 0,03045848 0,06754202 ! phospholipid efflux GO:0033700 16 10 0,000 0,03045848 0,06747983 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03045848 0,06741775 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03045848 0,06735578 ! lung alveolus development GO:0048286 26 10 0,000 0,03045848 0,06729393 ! pathogenesis GO:0009405 13 10 0,000 0,03045848 0,0672322 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03045848 0,06717057 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03045848 0,06710906 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03045848 0,06704766 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03045848 0,06698637 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03045848 0,0669252 ! endoderm development GO:0007492 16 10 0,000 0,03045848 0,06686414 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03045848 0,06680318 ! arginine catabolic process GO:0006527 13 10 0,000 0,03045848 0,06674234 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03045848 0,06668161 ! proline metabolic process GO:0006560 13 10 0,000 0,03045848 0,06662099 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03045848 0,06656048 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03045848 0,06650008 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03045848 0,06643979 ! V(D)J recombination GO:0033151 28 10 0,000 0,03045848 0,06637961 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03045848 0,06631954 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03045848 0,06625958 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03045848 0,06619972 ! B cell proliferation GO:0042100 18 10 0,000 0,03045848 0,06613998 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03045848 0,06608034 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03045848 0,0660208 ! multicellular organism growth GO:0035264 18 10 0,000 0,03045848 0,06596138 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03045848 0,06590206 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03045848 0,06584285 ! epithelial cell development GO:0002064 20 10 0,000 0,03045848 0,06578375 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03045848 0,06572475 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03045848 0,06566585 ! macroautophagy GO:0016236 17 10 0,000 0,03045848 0,06560707 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03045848 0,06554838 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03045848 0,06548981 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03045848 0,06543133 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03045848 0,06537296 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03045848 0,0653147 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03045848 0,06525654 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03045848 0,06519848 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03045848 0,06514053 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03045848 0,06508268 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03045848 0,06502493 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03045848 0,06496728 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03045848 0,06490974 ! response to dsRNA GO:0043331 20 10 0,000 0,03045848 0,06485229 ! DNA ligation GO:0006266 19 10 0,000 0,03045848 0,06479495 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03045848 0,06473771 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03045848 0,06468058 ! melanosome localization GO:0032400 16 10 0,000 0,03045848 0,06462354 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03045848 0,0645666 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03045848 0,06450976 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03045848 0,06445303 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03045848 0,06439639 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03045848 0,06433985 ! mRNA cleavage GO:0006379 17 10 0,000 0,03045848 0,06428341 ! protein sumoylation GO:0016925 15 10 0,000 0,03045848 0,06422708 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03045848 0,06417083 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03045848 0,06411469 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03045848 0,06405865 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03045848 0,0640027 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03045848 0,06394685 ! salivary gland development GO:0007431 27 10 0,000 0,03045848 0,0638911 ! prophase GO:0051324 15 10 0,000 0,03045848 0,06383545 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03045848 0,06377989 ! apical protein localization GO:0045176 15 10 0,000 0,03045848 0,06372443 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03045848 0,06366906 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03045848 0,0636138 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03045848 0,06355862 ! midbrain development GO:0030901 13 10 0,000 0,03045848 0,06350355 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03045848 0,06344857 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03045848 0,06339368 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03045848 0,06333889 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03045848 0,06328419 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03045848 0,06322959 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03045848 0,06317508 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03045848 0,06312067 ! detection of calcium ion GO:0005513 23 10 0,000 0,03045848 0,06306634 ! oocyte development GO:0048599 17 10 0,000 0,03045848 0,06301212 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03045848 0,06295798 ! blastocyst formation GO:0001825 17 10 0,000 0,03045848 0,06290394 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03045848 0,06284999 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03045848 0,06279614 ! activation of innate immune response GO:0002218 12 10 0,000 0,03045848 0,06274237 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03045848 0,0626887 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03045848 0,06263512 ! response to nicotine GO:0035094 20 10 0,000 0,03045848 0,06258163 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03045848 0,06252824 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03045848 0,06247493 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03045848 0,06242171 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,03105063 0,06358113 ! ossification GO:0001503 188 90 1,000 0,03169365 0,06484263 ! bone development GO:0060348 189 91 1,000 0,03234193 0,06611273 ! regulation of defense response GO:0031347 149 92 1,000 0,03299542 0,06739132 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03345337 0,06826871 ! respiratory burst GO:0045730 17 11 0,000 0,03345337 0,06821086 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03345337 0,0681531 ! neuron fate specification GO:0048665 17 11 0,000 0,03345337 0,06809544 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03345337 0,06803788 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03345337 0,06798042 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03345337 0,06792305 ! thyroid gland development GO:0030878 26 11 0,000 0,03345337 0,06786578 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03345337 0,06780861 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03345337 0,06775153 ! response to pain GO:0048265 24 11 0,000 0,03345337 0,06769455 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03345337 0,06763766 ! T cell proliferation GO:0042098 26 11 0,000 0,03345337 0,06758087 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03345337 0,06752417 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03345337 0,06746757 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03345337 0,06741107 ! bone resorption GO:0045453 16 11 0,000 0,03345337 0,06735466 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03345337 0,06729834 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03345337 0,06724212 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03345337 0,06718599 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03345337 0,06712995 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03345337 0,06707401 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03345337 0,06701816 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03345337 0,06696241 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03345337 0,06690675 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03345337 0,06685118 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03345337 0,0667957 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03345337 0,06674031 ! UV protection GO:0009650 19 11 0,000 0,03345337 0,06668502 ! adult heart development GO:0007512 14 11 0,000 0,03345337 0,06662981 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03345337 0,0665747 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03345337 0,06651968 ! temperature homeostasis GO:0001659 17 11 0,000 0,03345337 0,06646475 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03345337 0,06640991 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03345337 0,06635516 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03345337 0,06630051 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03345337 0,06624594 ! regulation of organ growth GO:0046620 13 11 0,000 0,03345337 0,06619146 ! pigment granule localization GO:0051875 20 11 0,000 0,03345337 0,06613707 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03345337 0,06608277 ! vasoconstriction GO:0042310 18 11 0,000 0,03345337 0,06602856 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03345337 0,06597444 ! embryonic axis specification GO:0000578 18 11 0,000 0,03345337 0,06592041 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03345337 0,06586646 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03345337 0,0658126 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03345337 0,06575884 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03345337 0,06570515 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03345337 0,06565156 ! zymogen activation GO:0031638 15 11 0,000 0,03345337 0,06559806 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03345337 0,06554464 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03345337 0,06549131 ! nucleosome positioning GO:0016584 15 11 0,000 0,03345337 0,06543806 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03345337 0,0653849 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03345337 0,06533183 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03345337 0,06527884 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03345337 0,06522594 ! acid secretion GO:0046717 18 11 0,000 0,03345337 0,06517313 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03345337 0,0651204 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03345337 0,06506776 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03345337 0,0650152 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03345337 0,06496272 ! oocyte differentiation GO:0009994 18 11 0,000 0,03345337 0,06491033 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03345337 0,06485803 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03345337 0,06480581 ! cholesterol efflux GO:0033344 19 11 0,000 0,03345337 0,06475367 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03345337 0,06470162 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03345337 0,06464965 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03345337 0,06459776 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03345337 0,06454596 ! embryonic gut development GO:0048566 15 11 0,000 0,03345337 0,06449424 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03345337 0,06444261 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03345337 0,06439105 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03345337 0,06433958 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03345337 0,06428819 ! defense response to fungus GO:0050832 13 11 0,000 0,03345337 0,06423688 ! lysogeny GO:0030069 21 11 0,000 0,03345337 0,06418566 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03345337 0,06413451 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03345337 0,06408345 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03345337 0,06403247 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03345337 0,06398157 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03345337 0,06393075 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,03365409 0,06426328 GO:0010498|proteasomal protein catabolic process, ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,03365409 0,06421232 ! positive regulation of immune response GO:0050778 156 96 1,000 0,0356608 0,06798722 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03643912 0,06941609 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03643912 0,06936117 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03643912 0,06930634 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03643912 0,06925159 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03643912 0,06919694 ! cartilage condensation GO:0001502 20 12 0,000 0,03643912 0,06914236 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03643912 0,06908788 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03643912 0,06903348 ! protein complex disassembly GO:0043241 27 12 0,000 0,03643912 0,06897916 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03643912 0,06892493 ! hippocampus development GO:0021766 26 12 0,000 0,03643912 0,06887079 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03643912 0,06881673 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03643912 0,06876276 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03643912 0,06870887 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03643912 0,06865506 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03643912 0,06860134 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03643912 0,06854771 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03643912 0,06849415 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03643912 0,06844068 ! drug transport GO:0015893 16 12 0,000 0,03643912 0,0683873 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03643912 0,068334 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03643912 0,06828078 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03643912 0,06822764 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03643912 0,06817459 ! focal adhesion formation GO:0048041 35 12 0,000 0,03643912 0,06812161 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03643912 0,06806872 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03643912 0,06801592 ! forebrain cell migration GO:0021885 21 12 0,000 0,03643912 0,06796319 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03643912 0,06791055 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03643912 0,06785799 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03643912 0,0678055 ! fear response GO:0042596 26 12 0,000 0,03643912 0,0677531 ! monoamine transport GO:0015844 18 12 0,000 0,03643912 0,06770079 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03643912 0,06764855 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03643912 0,06759639 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03643912 0,06754431 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03643912 0,06749231 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03643912 0,0674404 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03643912 0,06738856 ! protein homotetramerization GO:0051289 21 12 0,000 0,03643912 0,0673368 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03643912 0,06728512 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03643912 0,06723353 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03643912 0,06718201 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03643912 0,06713056 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03643912 0,0670792 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03643912 0,06702792 ! cranial nerve development GO:0021545 20 12 0,000 0,03643912 0,06697671 ! fucose catabolic process GO:0019317 22 12 0,000 0,03643912 0,06692559 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03643912 0,06687454 ! histone methylation GO:0016571 26 12 0,000 0,03643912 0,06682356 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03643912 0,06677267 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03643912 0,06672185 ! gland morphogenesis GO:0022612 29 12 0,000 0,03643912 0,06667112 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03643912 0,06662045 ! T cell homeostasis GO:0043029 25 12 0,000 0,03643912 0,06656987 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03643912 0,06651936 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03643912 0,06646893 ! spleen development GO:0048536 22 12 0,000 0,03643912 0,06641857 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03643912 0,06636829 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03643912 0,06631809 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03643912 0,06626796 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03643912 0,06621791 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03643912 0,06616794 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,03643912 0,06611804 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03643912 0,06606821 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03643912 0,06601846 ! response to cold GO:0009409 17 12 0,000 0,03643912 0,06596879 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03643912 0,06591919 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03643912 0,06586966 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,03771278 0,06812082 GO:0060538|skeletal muscle organ development, ! cGMP metabolic process GO:0046068 18 13 0,000 0,03941574 0,07114349 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03941574 0,07109015 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03941574 0,0710369 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03941574 0,07098373 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03941574 0,07093064 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03941574 0,07087763 ! lipid localization GO:0010876 28 13 0,000 0,03941574 0,07082469 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03941574 0,07077184 ! organelle fusion GO:0048284 32 13 0,000 0,03941574 0,07071906 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03941574 0,07066637 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03941574 0,07061375 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03941574 0,07056121 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03941574 0,07050875 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03941574 0,07045636 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03941574 0,07040406 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03941574 0,07035183 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03941574 0,07029968 ! methionine metabolic process GO:0006555 27 13 0,000 0,03941574 0,0702476 ! plasma membrane organization GO:0007009 24 13 0,000 0,03941574 0,07019561 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03941574 0,07014369 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03941574 0,07009184 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03941574 0,07004008 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03941574 0,06998839 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03941574 0,06993677 ! exocrine system development GO:0035272 32 13 0,000 0,03941574 0,06988524 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03941574 0,06983377 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03941574 0,06978239 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03941574 0,06973108 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03941574 0,06967984 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03941574 0,06962868 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03941574 0,0695776 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03941574 0,06952659 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03941574 0,06947565 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03941574 0,06942479 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03941574 0,06937401 ! ribosome assembly GO:0042255 17 13 0,000 0,03941574 0,06932329 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03941574 0,06927266 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03941574 0,06922209 ! chromatin silencing GO:0006342 26 13 0,000 0,03941574 0,0691716 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03941574 0,06912119 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03941574 0,06907084 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03941574 0,06902057 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03941574 0,06897038 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03941574 0,06892025 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03941574 0,0688702 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03941574 0,06882022 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03941574 0,06877032 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03941574 0,06872048 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03941574 0,06867072 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03941574 0,06862103 ! embryonic placenta development GO:0001892 23 13 0,000 0,03941574 0,06857141 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03941574 0,06852187 ! insulin secretion GO:0030073 23 13 0,000 0,03941574 0,06847239 ! actin filament polymerization GO:0030041 24 13 0,000 0,03941574 0,06842299 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03941574 0,06837366 ! acrosome reaction GO:0007340 18 13 0,000 0,03941574 0,0683244 ! rRNA transcription GO:0009303 25 14 0,000 0,04238326 0,0734155 ! lactation GO:0007595 26 14 0,000 0,04238326 0,07336268 ! reproductive cellular process GO:0048610 20 14 0,000 0,04238326 0,07330994 ! tRNA modification GO:0006400 20 14 0,000 0,04238326 0,07325728 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04238326 0,07320469 ! regulation of S phase GO:0033261 23 14 0,000 0,04238326 0,07315217 ! water transport GO:0006833 21 14 0,000 0,04238326 0,07309973 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04238326 0,07304737 ! non-recombinational repair GO:0000726 25 14 0,000 0,04238326 0,07299508 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04238326 0,07294287 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04238326 0,07289073 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04238326 0,07283866 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04238326 0,07278667 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04238326 0,07273476 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04238326 0,07268291 ! palate development GO:0060021 31 14 0,000 0,04238326 0,07263115 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04238326 0,07257945 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04238326 0,07252783 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04238326 0,07247628 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04238326 0,07242481 ! arginine metabolic process GO:0006525 17 14 0,000 0,04238326 0,07237341 ! regulation of heart rate GO:0002027 24 14 0,000 0,04238326 0,07232208 ! organic alcohol transport GO:0015850 29 14 0,000 0,04238326 0,07227082 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04238326 0,07221964 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04238326 0,07216853 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04238326 0,07211749 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04238326 0,07206652 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04238326 0,07201563 ! L-amino acid transport GO:0015807 30 14 0,000 0,04238326 0,0719648 ! bone mineralization GO:0030282 17 14 0,000 0,04238326 0,07191405 ! stem cell development GO:0048864 43 14 0,000 0,04238326 0,07186337 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04238326 0,07181277 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04238326 0,07176223 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04238326 0,07171176 ! cerebellum development GO:0021549 21 14 0,000 0,04238326 0,07166137 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04238326 0,07161105 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04238326 0,07156079 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04238326 0,07151061 ! cofactor transport GO:0051181 26 14 0,000 0,04238326 0,0714605 ! NADP metabolic process GO:0006739 24 14 0,000 0,04238326 0,07141045 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04238326 0,07136048 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04238326 0,07131058 ! intestinal absorption GO:0050892 25 14 0,000 0,04238326 0,07126075 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04238326 0,07121098 ! oxygen transport GO:0015671 21 14 0,000 0,04238326 0,07116129 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04238326 0,07111167 ! male genitalia development GO:0030539 24 14 0,000 0,04238326 0,07106211 ! regulation of RNA stability GO:0043487 32 14 0,000 0,04238326 0,07101262 ! regulation of axon extension GO:0030516 37 14 0,000 0,04238326 0,07096321 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04238326 0,07091386 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04534172 0,0758111 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04534172 0,07575845 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04534172 0,07570588 ! superoxide anion generation GO:0042554 20 15 0,000 0,04534172 0,07565338 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04534172 0,07560095 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04534172 0,07554859 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04534172 0,07549631 ! copper ion transport GO:0006825 20 15 0,000 0,04534172 0,0754441 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04534172 0,07539196 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04534172 0,0753399 ! sulfate transport GO:0008272 23 15 0,000 0,04534172 0,0752879 ! response to cAMP GO:0051591 22 15 0,000 0,04534172 0,07523598 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04534172 0,07518413 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04534172 0,07513235 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04534172 0,07508064 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04534172 0,075029 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04534172 0,07497744 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04534172 0,07492594 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04534172 0,07487452 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04534172 0,07482316 ! pituitary gland development GO:0021983 29 15 0,000 0,04534172 0,07477188 ! vesicle coating GO:0006901 33 15 0,000 0,04534172 0,07472066 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04534172 0,07466952 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04534172 0,07461845 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04534172 0,07456744 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04534172 0,07451651 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04534172 0,07446564 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04534172 0,07441485 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04534172 0,07436412 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04534172 0,07431347 ! histone deacetylation GO:0016575 20 15 0,000 0,04534172 0,07426288 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04534172 0,07421236 ! tissue regeneration GO:0042246 26 15 0,000 0,04534172 0,07416191 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04534172 0,07411153 ! water homeostasis GO:0030104 27 15 0,000 0,04534172 0,07406122 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04534172 0,07401097 ! muscle maintenance GO:0046716 26 15 0,000 0,04534172 0,07396079 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04534172 0,07391068 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04534172 0,07386064 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04534172 0,07381067 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04534172 0,07376076 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04534172 0,07371093 ! cell killing GO:0001906 29 15 0,000 0,04534172 0,07366115 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04534172 0,07361145 ! detection of bacterium GO:0016045 18 15 0,000 0,04534172 0,07356181 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04534172 0,07351224 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04534172 0,07346274 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04534172 0,0734133 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04534172 0,07336393 ! peptide hormone processing GO:0016486 23 15 0,000 0,04534172 0,07331463 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04829113 0,0780312 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04829113 0,07797883 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04829113 0,07792653 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04829113 0,0778743 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04829113 0,07782214 ! bone remodeling GO:0046849 27 16 0,000 0,04829113 0,07777005 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04829113 0,07771803 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04829113 0,07766608 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04829113 0,0776142 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04829113 0,07756239 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04829113 0,07751064 ! startle response GO:0001964 28 16 0,000 0,04829113 0,07745897 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04829113 0,07740737 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04829113 0,07735583 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04829113 0,07730436 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04829113 0,07725296 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04829113 0,07720163 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04829113 0,07715037 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04829113 0,07709918 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04829113 0,07704805 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04829113 0,07699699 ! response to osmotic stress GO:0006970 25 16 0,000 0,04829113 0,076946 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04829113 0,07689507 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04829113 0,07684422 ! fructose metabolic process GO:0006000 25 16 0,000 0,04829113 0,07679343 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04829113 0,07674271 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04829113 0,07669205 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04829113 0,07664146 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04829113 0,07659094 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04829113 0,07654049 ! axon cargo transport GO:0008088 43 16 0,000 0,04829113 0,0764901 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04829113 0,07643977 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04829113 0,07638952 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04829113 0,07633933 ! DNA replication initiation GO:0006270 27 16 0,000 0,04829113 0,0762892 ! neuron recognition GO:0008038 35 16 0,000 0,04829113 0,07623914 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04829113 0,07618915 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04829113 0,07613922 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04829113 0,07608936 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04829113 0,07603957 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04829113 0,07598983 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04829113 0,07594017 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04829113 0,07589057 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04829113 0,07584103 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04829113 0,07579156 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04829113 0,07574215 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04829113 0,07569281 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,04829113 0,07564353 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,04829113 0,07559431 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05123153 0,08014503 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05123153 0,08009295 ! metencephalon development GO:0022037 30 17 0,000 0,05123153 0,08004094 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05123153 0,079989 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05123153 0,07993713 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05123153 0,07988532 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05123153 0,07983358 ! signal complex assembly GO:0007172 41 17 0,000 0,05123153 0,07978191 ! endothelial cell migration GO:0043542 28 17 0,000 0,05123153 0,07973031 ! inositol metabolic process GO:0006020 28 17 0,000 0,05123153 0,07967877 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05123153 0,0796273 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05123153 0,07957589 ! glial cell development GO:0021782 27 17 0,000 0,05123153 0,07952455 ! limbic system development GO:0021761 36 17 0,000 0,05123153 0,07947328 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05123153 0,07942207 ! adult walking behavior GO:0007628 33 17 0,000 0,05123153 0,07937093 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05123153 0,07931986 ! heart looping GO:0001947 30 17 0,000 0,05123153 0,07926885 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05123153 0,0792179 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05123153 0,07916702 ! myoblast differentiation GO:0045445 45 17 0,000 0,05123153 0,07911621 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05123153 0,07906546 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,05123153 0,07901478 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05123153 0,07896416 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05123153 0,07891361 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05123153 0,07886312 ! glycine metabolic process GO:0006544 28 17 0,000 0,05123153 0,07881269 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05123153 0,07876234 ! NAD metabolic process GO:0019674 29 17 0,000 0,05123153 0,07871204 ! membrane budding GO:0006900 37 17 0,000 0,05123153 0,07866181 ! DNA integration GO:0015074 29 17 0,000 0,05123153 0,07861164 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05123153 0,07856154 ! regulation of protein binding GO:0043393 33 17 0,000 0,05123153 0,0785115 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05123153 0,07846152 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05123153 0,07841161 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05123153 0,07836176 ! genitalia development GO:0048806 30 17 0,000 0,05123153 0,07831198 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05123153 0,07826226 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05123153 0,0782126 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05123153 0,078163 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05123153 0,07811347 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05123153 0,078064 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05123153 0,07801459 ! steroid catabolic process GO:0006706 31 17 0,000 0,05123153 0,07796525 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05123153 0,07791596 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05123153 0,07786674 ! gas transport GO:0015669 25 17 0,000 0,05123153 0,07781759 ! organic cation transport GO:0015695 31 17 0,000 0,05123153 0,07776849 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05123153 0,07771945 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05123153 0,07767048 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05123153 0,07762157 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05123153 0,07757272 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05123153 0,07752393 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05416294 0,08190825 ! neuron maturation GO:0042551 42 18 0,000 0,05416294 0,0818568 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05416294 0,08180542 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05416294 0,0817541 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05416294 0,08170284 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05416294 0,08165165 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05416294 0,08160052 ! memory GO:0007613 31 18 0,000 0,05416294 0,08154946 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05416294 0,08149845 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05416294 0,08144752 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05416294 0,08139665 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05416294 0,08134584 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,05416294 0,08129509 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05416294 0,08124441 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05416294 0,08119379 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05416294 0,08114323 ! response to retinoic acid GO:0032526 26 18 0,000 0,05416294 0,08109274 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05416294 0,08104231 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05416294 0,08099194 ! response to fungus GO:0009620 21 18 0,000 0,05416294 0,08094163 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05416294 0,08089139 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05416294 0,08084121 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05416294 0,08079109 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05416294 0,08074103 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05416294 0,08069104 ! vitamin transport GO:0051180 27 18 0,000 0,05416294 0,08064111 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05416294 0,08059124 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05416294 0,08054143 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05416294 0,08049168 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05416294 0,08044199 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05416294 0,08039237 ! nerve development GO:0021675 28 18 0,000 0,05416294 0,0803428 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05416294 0,0802933 ! protein secretion GO:0009306 39 19 0,000 0,05708539 0,08457355 ! positive regulation of translation GO:0045727 30 19 0,000 0,05708539 0,08452151 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05708539 0,08446952 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05708539 0,08441761 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05708539 0,08436575 ! skin development GO:0043588 36 19 0,000 0,05708539 0,08431396 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05708539 0,08426224 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05708539 0,08421057 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05708539 0,08415897 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05708539 0,08410744 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05708539 0,08405596 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05708539 0,08400455 ! cerebral cortex development GO:0021987 36 19 0,000 0,05708539 0,08395321 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05708539 0,08390192 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05708539 0,0838507 ! heme metabolic process GO:0042168 36 19 0,000 0,05708539 0,08379954 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05708539 0,08374844 ! neuromuscular junction development GO:0007528 34 19 0,000 0,05708539 0,08369741 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05708539 0,08364643 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05708539 0,08359552 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,05708539 0,08354468 ! peptide cross-linking GO:0018149 37 19 0,000 0,05708539 0,08349389 ! protein export from nucleus GO:0006611 36 19 0,000 0,05708539 0,08344316 ! heart process GO:0003015 30 19 0,000 0,05708539 0,0833925 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05708539 0,0833419 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05708539 0,08329136 ! visual learning GO:0008542 36 19 0,000 0,05708539 0,08324088 ! cellular pigmentation GO:0033059 36 19 0,000 0,05708539 0,08319046 ! G1 phase GO:0051318 40 19 0,000 0,05708539 0,0831401 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05708539 0,0830898 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05708539 0,08303957 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05708539 0,08298939 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05708539 0,08293928 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05708539 0,08288923 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05708539 0,08283923 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05708539 0,0827893 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05708539 0,08273943 ! cilium assembly GO:0042384 37 19 0,000 0,05708539 0,08268961 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05708539 0,08263986 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05999891 0,08680539 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,05999891 0,08675323 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05999891 0,08670112 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05999891 0,08664908 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05999891 0,0865971 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,05999891 0,08654519 ! cAMP metabolic process GO:0046058 36 20 0,000 0,05999891 0,08649333 ! response to vitamin GO:0033273 31 20 0,000 0,05999891 0,08644154 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05999891 0,08638981 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05999891 0,08633814 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05999891 0,08628653 ! response to alkaloid GO:0043279 38 20 0,000 0,05999891 0,08623499 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05999891 0,0861835 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,05999891 0,08613208 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05999891 0,08608072 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05999891 0,08602942 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05999891 0,08597818 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05999891 0,08592701 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05999891 0,08587589 ! body fluid secretion GO:0007589 31 20 0,000 0,05999891 0,08582483 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05999891 0,08577384 ! peptide secretion GO:0002790 35 20 0,000 0,05999891 0,0857229 ! stem cell differentiation GO:0048863 53 20 0,000 0,05999891 0,08567203 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05999891 0,08562122 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05999891 0,08557046 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05999891 0,08551977 ! sensory perception of pain GO:0019233 30 20 0,000 0,05999891 0,08546914 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05999891 0,08541856 ! diencephalon development GO:0021536 34 20 0,000 0,05999891 0,08536805 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05999891 0,08531759 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05999891 0,0852672 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05999891 0,08521687 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,05999891 0,08516659 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05999891 0,08511637 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05999891 0,08506622 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05999891 0,08501612 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05999891 0,08496608 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05999891 0,0849161 ! regulation of glucose import GO:0046324 29 20 0,000 0,05999891 0,08486618 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,05999891 0,08481632 ! actin filament-based movement GO:0030048 43 20 0,000 0,05999891 0,08476651 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05999891 0,08471677 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,05999891 0,08466708 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05999891 0,08461745 ! negative regulation of translation GO:0017148 29 20 0,000 0,05999891 0,08456788 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05999891 0,08451837 ! regulation of cell killing GO:0031341 42 21 0,000 0,06290352 0,08855814 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06290352 0,08850635 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06290352 0,08845463 ! hormone secretion GO:0046879 38 21 0,000 0,06290352 0,08840296 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06290352 0,08835135 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06290352 0,08829981 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06290352 0,08824832 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06290352 0,08819689 ! axis specification GO:0009798 38 21 0,000 0,06290352 0,08814552 ! ovarian follicle development GO:0001541 35 21 0,000 0,06290352 0,08809422 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06290352 0,08804297 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06290352 0,08799178 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06290352 0,08794065 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06290352 0,08788959 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06290352 0,08783858 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06290352 0,08778763 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06290352 0,08773673 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06290352 0,0876859 ! cytolysis GO:0019835 24 21 0,000 0,06290352 0,08763513 ! vasodilation GO:0042311 39 21 0,000 0,06290352 0,08758441 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06290352 0,08753376 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06290352 0,08748316 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06290352 0,08743262 ! oogenesis GO:0048477 36 21 0,000 0,06290352 0,08738214 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,06290352 0,08733172 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,06290352 0,08728135 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06290352 0,08723105 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06290352 0,0871808 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,06290352 0,08713061 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06290352 0,08708048 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06290352 0,0870304 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06290352 0,08698038 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06290352 0,08693042 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06290352 0,08688052 ! collagen catabolic process GO:0030574 28 21 0,000 0,06290352 0,08683067 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06290352 0,08678089 ! gut development GO:0048565 39 21 0,000 0,06290352 0,08673116 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06579925 0,09067182 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06579925 0,09061992 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06579925 0,09056808 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06579925 0,09051629 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06579925 0,09046457 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06579925 0,09041291 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,06579925 0,0903613 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06579925 0,09030975 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06579925 0,09025827 ! regeneration GO:0031099 41 22 0,000 0,06579925 0,09020684 ! keratinization GO:0031424 28 22 0,000 0,06579925 0,09015547 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06579925 0,09010415 ! sensory perception of taste GO:0050909 28 22 0,000 0,06579925 0,0900529 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06579925 0,0900017 ! vacuolar transport GO:0007034 36 22 0,000 0,06579925 0,08995057 ! lysosome organization GO:0007040 41 22 0,000 0,06579925 0,08989949 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06579925 0,08984847 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06579925 0,0897975 ! fucose metabolic process GO:0006004 39 22 0,000 0,06579925 0,0897466 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06579925 0,08969575 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06579925 0,08964496 ! ureteric bud development GO:0001657 43 22 0,000 0,06579925 0,08959423 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06579925 0,08954355 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06579925 0,08949293 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06579925 0,08944237 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,06579925 0,08939187 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06579925 0,08934142 ! sarcomere organization GO:0045214 30 22 0,000 0,06579925 0,08929103 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06579925 0,0892407 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06579925 0,08919042 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06579925 0,0891402 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06579925 0,08909004 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,06579925 0,08903993 ! protein stabilization GO:0050821 39 22 0,000 0,06579925 0,08898988 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06868613 0,09284204 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,06868613 0,09278991 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06868613 0,09273784 ! gluconeogenesis GO:0006094 33 23 0,000 0,06868613 0,09268583 ! viral genome replication GO:0019079 41 23 0,000 0,06868613 0,09263388 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06868613 0,09258198 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06868613 0,09253014 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06868613 0,09247836 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06868613 0,09242664 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06868613 0,09237498 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06868613 0,09232337 ! visual behavior GO:0007632 42 23 0,000 0,06868613 0,09227182 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06868613 0,09222033 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06868613 0,0921689 ! response to ethanol GO:0045471 46 23 0,000 0,06868613 0,09211752 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06868613 0,0920662 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,06868613 0,09201494 ! peroxisome organization GO:0007031 37 23 0,000 0,06868613 0,09196374 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06868613 0,09191259 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06868613 0,0918615 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06868613 0,09181046 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06868613 0,09175949 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06868613 0,09170856 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06868613 0,0916577 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06868613 0,09160689 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06868613 0,09155614 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06868613 0,09150544 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06868613 0,09145481 ! fatty acid transport GO:0015908 44 23 0,000 0,06868613 0,09140422 ! platelet activation GO:0030168 37 23 0,000 0,06868613 0,09135369 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06868613 0,09130322 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06868613 0,09125281 ! hormone transport GO:0009914 40 23 0,000 0,06868613 0,09120245 ! cell-cell recognition GO:0009988 25 23 0,000 0,06868613 0,09115214 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06868613 0,09110189 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06868613 0,0910517 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,06868613 0,09100156 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06868613 0,09095148 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06868613 0,09090145 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07156419 0,09465829 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,07156419 0,09460628 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07156419 0,09455433 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07156419 0,09450243 ! vesicle docking GO:0048278 47 24 0,000 0,07156419 0,09445059 ! spinal cord development GO:0021510 47 24 0,000 0,07156419 0,09439881 ! vacuole organization GO:0007033 43 24 0,000 0,07156419 0,09434709 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07156419 0,09429542 ! digestive system process GO:0022600 39 24 0,000 0,07156419 0,09424381 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07156419 0,09419225 ! regulation of behavior GO:0050795 43 24 0,000 0,07156419 0,09414075 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07156419 0,09408931 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07156419 0,09403792 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07156419 0,09398659 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07156419 0,09393532 ! membrane depolarization GO:0051899 39 24 0,000 0,07156419 0,0938841 ! pallium development GO:0021543 49 24 0,000 0,07156419 0,09383293 ! pentose metabolic process GO:0019321 35 24 0,000 0,07156419 0,09378183 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07156419 0,09373078 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07156419 0,09367978 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07156419 0,09362884 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07156419 0,09357795 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07156419 0,09352712 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07156419 0,09347635 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07156419 0,09342563 ! regulation of amine transport GO:0051952 40 24 0,000 0,07156419 0,09337496 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,07443344 0,09706605 ! myelination GO:0042552 45 25 0,000 0,07443344 0,09701347 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07443344 0,09696094 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07443344 0,09690848 ! phototransduction GO:0007602 33 25 0,000 0,07443344 0,09685607 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07443344 0,09680371 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,07443344 0,09675141 ! sperm motility GO:0030317 31 25 0,000 0,07443344 0,09669917 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07443344 0,09664699 ! receptor metabolic process GO:0043112 46 25 0,000 0,07443344 0,09659486 ! chromosome condensation GO:0030261 45 25 0,000 0,07443344 0,09654278 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07443344 0,09649077 ! neural crest cell development GO:0014032 54 25 0,000 0,07443344 0,09643881 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07443344 0,0963869 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,07443344 0,09633505 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07443344 0,09628326 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07443344 0,09623152 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07443344 0,09617984 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,07443344 0,09612822 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07443344 0,09607664 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07443344 0,09602513 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07443344 0,09597367 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07443344 0,09592226 ! telomere organization GO:0032200 43 25 0,000 0,07443344 0,09587091 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07443344 0,09581962 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07443344 0,09576838 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07729393 0,09939561 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07729393 0,09934252 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07729393 0,09928948 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07729393 0,09923649 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07729393 0,09918357 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07729393 0,0991307 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07729393 0,09907788 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07729393 0,09902513 ! molting cycle process GO:0022404 50 26 0,000 0,07729393 0,09897243 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07729393 0,09891978 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07729393 0,09886719 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,07729393 0,09881466 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07729393 0,09876218 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,07729393 0,09870976 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,07729393 0,0986574 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07729393 0,09860508 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07729393 0,09855283 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07729393 0,09850063 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07729393 0,09844849 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,07729393 0,0983964 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07729393 0,09834436 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07729393 0,09829238 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07729393 0,09824046 ! blastocyst development GO:0001824 49 26 0,000 0,07729393 0,09818859 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07729393 0,09813678 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07729393 0,09808502 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07729393 0,09803331 ! neuron fate commitment GO:0048663 48 27 0,000 0,08014567 0,10159667 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,08014567 0,10154317 ! iron ion transport GO:0006826 59 27 0,000 0,08014567 0,10148972 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,08014567 0,10143633 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,08014567 0,101383 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,08014567 0,10132973 ! fat cell differentiation GO:0045444 50 27 0,000 0,08014567 0,10127651 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,08014567 0,10122335 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,08014567 0,10117024 ! autophagy GO:0006914 41 27 0,000 0,08014567 0,10111719 ! male gonad development GO:0008584 44 27 0,000 0,08014567 0,10106419 ! response to toxin GO:0009636 47 27 0,000 0,08014567 0,10101125 ! primary neural tube formation GO:0014020 51 27 0,000 0,08014567 0,10095836 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,08014567 0,10090553 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,08014567 0,10085276 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,08014567 0,10080004 ! glutathione metabolic process GO:0006749 39 27 0,000 0,08014567 0,10074737 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,08014567 0,10069476 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,08014567 0,10064221 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,08014567 0,10058971 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,08014567 0,10053726 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08298869 0,10404939 ! circadian rhythm GO:0007623 50 28 0,000 0,08298869 0,1039952 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08298869 0,10394106 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,08298869 0,10388698 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,08298869 0,10383296 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08298869 0,10377899 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08298869 0,10372508 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08298869 0,10367122 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08298869 0,10361742 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08298869 0,10356368 ! synaptogenesis GO:0007416 42 28 0,000 0,08298869 0,10350999 ! lipid oxidation GO:0034440 43 28 0,000 0,08298869 0,10345636 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08298869 0,10340278 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08298869 0,10334926 ! translational initiation GO:0006413 65 29 0,000 0,08582301 0,10682368 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08582301 0,10676844 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,08582301 0,10671326 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08582301 0,10665814 ! catechol metabolic process GO:0009712 54 29 0,000 0,08582301 0,10660308 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08582301 0,10654807 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08582301 0,10649312 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08582301 0,10643823 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08582301 0,10638339 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08582301 0,10632861 ! cell fate determination GO:0001709 60 29 0,000 0,08582301 0,10627389 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08582301 0,10621922 ! detection of light stimulus GO:0009583 38 29 0,000 0,08582301 0,10616461 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,08582301 0,10611005 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08582301 0,10605556 ! tissue homeostasis GO:0001894 48 29 0,000 0,08582301 0,10600111 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,08582301 0,10594672 ! phenol metabolic process GO:0018958 55 30 0,000 0,08864867 0,10937882 ! zinc ion transport GO:0006829 45 30 0,000 0,08864867 0,10932276 ! membrane docking GO:0022406 61 30 0,000 0,08864867 0,10926675 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08864867 0,10921081 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08864867 0,10915492 ! acute-phase response GO:0006953 49 30 0,000 0,08864867 0,10909908 ! myofibril assembly GO:0030239 47 30 0,000 0,08864867 0,10904331 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,08864867 0,10898759 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,08864867 0,10893192 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,08864867 0,10887632 ! phospholipid transport GO:0015914 51 30 0,000 0,08864867 0,10882077 ! ensheathment of neurons GO:0007272 57 30 0,000 0,08864867 0,10876528 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,08864867 0,10870984 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08864867 0,10865446 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,08864867 0,10859914 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,08864867 0,10854387 ! eye morphogenesis GO:0048592 60 30 0,000 0,08864867 0,10848866 ! response to heat GO:0009408 50 30 0,000 0,08864867 0,10843351 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09146569 0,11182239 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,09146569 0,11176559 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09146569 0,11170886 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09146569 0,11165218 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,09146569 0,11159557 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09146569 0,111539 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09146569 0,1114825 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09146569 0,11142605 ! ovulation cycle process GO:0022602 49 31 0,000 0,09146569 0,11136966 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09146569 0,11131333 ! peptide transport GO:0015833 55 31 0,000 0,09146569 0,11125705 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09146569 0,11120084 ! iron ion homeostasis GO:0055072 54 31 0,000 0,09146569 0,11114467 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09146569 0,11108857 ! mesoderm formation GO:0001707 69 31 0,000 0,09146569 0,11103252 ! natural killer cell activation GO:0030101 45 31 0,000 0,09146569 0,11097653 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09146569 0,11092059 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,09146569 0,11086471 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09146569 0,11080889 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,09146569 0,11075312 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09146569 0,11069741 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0942741 0,11403895 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0942741 0,11398165 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0942741 0,1139244 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0942741 0,11386721 ! cholesterol transport GO:0030301 56 32 0,000 0,0942741 0,11381007 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0942741 0,113753 ! spliceosome assembly GO:0000245 67 32 0,000 0,0942741 0,11369598 ! spindle organization GO:0007051 46 32 0,000 0,0942741 0,11363902 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0942741 0,11358211 ! metanephros development GO:0001656 74 32 0,000 0,0942741 0,11352526 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0942741 0,11346847 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,0942741 0,11341174 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0942741 0,11335506 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,0942741 0,11329844 ! muscle cell development GO:0055001 49 32 0,000 0,0942741 0,11324188 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0942741 0,11318537 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0942741 0,11312892 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0942741 0,11307252 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,0942741 0,11301618 ! ovulation cycle GO:0042698 51 32 0,000 0,0942741 0,1129599 ! peripheral nervous system development GO:0007422 64 32 0,000 0,0942741 0,11290367 ! BMP signaling pathway GO:0030509 64 32 0,000 0,0942741 0,1128475 ! hindbrain development GO:0030902 61 32 0,000 0,0942741 0,11279139 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0942741 0,11273533 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0942741 0,11267932 ! gene silencing GO:0016458 65 32 0,000 0,0942741 0,11262338 ! post-embryonic development GO:0009791 69 33 0,000 0,09707391 0,11591059 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09707391 0,11585309 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,09707391 0,11579566 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09707391 0,11573828 ! formation of primary germ layer GO:0001704 72 33 0,000 0,09707391 0,11568095 ! sterol transport GO:0015918 57 33 0,000 0,09707391 0,11562368 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,09707391 0,11556647 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09707391 0,11550932 ! adult locomotory behavior GO:0008344 59 33 0,000 0,09707391 0,11545222 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,09707391 0,11539518 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,09707391 0,11533819 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,09986517 0,11859605 ! glial cell differentiation GO:0010001 63 34 0,000 0,09986517 0,11853754 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,09986517 0,11847909 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,09986517 0,1184207 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,09986517 0,11836236 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,09986517 0,11830409 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,09986517 0,11824587 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,09986517 0,1181877 ! mismatch repair GO:0006298 46 34 0,000 0,09986517 0,1181296 ! spermatid development GO:0007286 63 34 0,000 0,09986517 0,11807155 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,09986517 0,11801356 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,09986517 0,11795562 ! placenta development GO:0001890 53 34 0,000 0,09986517 0,11789774 ! regulation of muscle development GO:0048634 70 35 0,000 0,10264789 0,1211235 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,10264789 0,12106413 ! negative regulation of secretion GO:0051048 63 35 0,000 0,10264789 0,12100481 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10264789 0,12094555 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,10264789 0,12088635 ! odontogenesis GO:0042476 66 35 0,000 0,10264789 0,12082721 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10264789 0,12076813 ! female gonad development GO:0008585 58 35 0,000 0,10264789 0,1207091 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10264789 0,12065013 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,10264789 0,12059122 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,10264789 0,12053237 ! vesicle localization GO:0051648 64 35 0,000 0,10264789 0,12047357 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,1054221 0,12366922 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,1054221 0,12360895 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,1054221 0,12354874 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,1054221 0,12348859 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,1054221 0,1234285 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,1054221 0,12336847 ! positive regulation of cell development GO:0010720 80 36 0,000 0,1054221 0,12330849 ! regulation of proteolysis GO:0030162 72 36 0,000 0,1054221 0,12324858 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,1054221 0,12318872 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,1054221 0,12312892 ! aerobic respiration GO:0009060 55 36 0,000 0,1054221 0,12306917 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,1054221 0,12300949 ! embryonic organ development GO:0048568 57 36 0,000 0,1054221 0,12294986 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,1054221 0,12289029 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,1054221 0,12283078 ! RNA export from nucleus GO:0006405 56 37 0,000 0,10818782 0,12599221 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,10818782 0,12593125 ! meiosis I GO:0007127 65 37 0,000 0,10818782 0,12587036 ! sister chromatid segregation GO:0000819 58 37 0,000 0,10818782 0,12580952 ! actomyosin structure organization GO:0031032 62 37 0,000 0,10818782 0,12574874 ! organic anion transport GO:0015711 68 37 0,000 0,10818782 0,12568803 ! tissue remodeling GO:0048771 76 37 0,000 0,10818782 0,12562736 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,10818782 0,12556676 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,10818782 0,12550622 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,10818782 0,12544573 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,10818782 0,12538531 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,10818782 0,12532494 ! glycogen metabolic process GO:0005977 61 37 0,000 0,10818782 0,12526463 ! pigment metabolic process GO:0042440 80 37 0,000 0,10818782 0,12520438 ! spermatid differentiation GO:0048515 66 37 0,000 0,10818782 0,12514418 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11094509 0,12827193 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,11094509 0,12821032 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11094509 0,12814877 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,11094509 0,12808727 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,11094509 0,12802584 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11094509 0,12796447 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,11094509 0,12790315 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11094509 0,1278419 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,11094509 0,1277807 ! glucan metabolic process GO:0044042 62 38 0,000 0,11094509 0,12771956 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,11369392 0,13082141 ! learning GO:0007612 77 39 0,000 0,11369392 0,13075888 ! ear morphogenesis GO:0042471 60 39 0,000 0,11369392 0,1306964 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11369392 0,13063399 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11369392 0,13057163 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11369392 0,13050934 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11369392 0,1304471 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,11369392 0,13038492 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,11369392 0,13032281 ! RNA modification GO:0009451 57 39 0,000 0,11369392 0,13026075 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11369392 0,13019875 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,11643434 0,13327356 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,11643434 0,13321019 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11643434 0,13314688 ! feeding behavior GO:0007631 59 40 0,000 0,11643434 0,13308362 ! negative regulation of binding GO:0051100 72 40 0,000 0,11643434 0,13302043 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,11643434 0,1329573 ! mesenchymal cell development GO:0014031 87 40 0,000 0,11643434 0,13289423 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,11643434 0,13283121 ! maintenance of protein location GO:0045185 91 40 0,000 0,11643434 0,13276826 ! cytokinesis GO:0000910 72 40 0,000 0,11643434 0,13270537 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,11916638 0,13575489 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,11916638 0,13569064 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,11916638 0,13562645 ! gliogenesis GO:0042063 88 41 0,000 0,11916638 0,13556233 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,11916638 0,13549826 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,11916638 0,13543426 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,11916638 0,13537031 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,11916638 0,13530643 ! female gamete generation GO:0007292 61 41 0,000 0,11916638 0,1352426 ! polyol metabolic process GO:0019751 66 41 0,000 0,11916638 0,13517884 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,12189007 0,13820335 ! regulation of tube size GO:0035150 71 42 0,000 0,12189007 0,13813825 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,12189007 0,13807321 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,12189007 0,13800824 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,12189007 0,13794332 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,12189007 0,13787847 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,12189007 0,13781368 ! neuron migration GO:0001764 79 42 0,000 0,12189007 0,13774894 ! regulation of protein secretion GO:0050708 71 42 0,000 0,12189007 0,13768427 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,12189007 0,13761966 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12460542 0,14061944 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,12460542 0,14055351 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,12460542 0,14048765 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,12460542 0,14042185 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,12460542 0,14035611 ! glucose transport GO:0015758 65 43 0,000 0,12460542 0,14029043 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12460542 0,14022481 ! striated muscle contraction GO:0006941 77 43 0,000 0,12460542 0,14015925 ! phagocytosis GO:0006909 90 43 0,000 0,12460542 0,14009376 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12460542 0,14002832 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,12731247 0,14300364 ! hexose transport GO:0008645 67 44 0,000 0,12731247 0,14293691 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,12731247 0,14287024 ! male sex differentiation GO:0046661 76 44 0,000 0,12731247 0,14280363 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,12731247 0,14273709 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,12731247 0,14267061 ! developmental growth GO:0048589 82 44 0,000 0,12731247 0,14260419 ! maintenance of location in cell GO:0051651 97 44 0,000 0,12731247 0,14253783 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,13001123 0,14549164 ! glycolysis GO:0006096 65 45 0,000 0,13001123 0,145424 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,13001123 0,14535642 ! leukocyte migration GO:0050900 68 45 0,000 0,13001123 0,14528891 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,13001123 0,14522146 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,13001123 0,14515407 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,13001123 0,14508674 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,13001123 0,14501948 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,13001123 0,14495228 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,13001123 0,14488514 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,13001123 0,14481807 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13270174 0,14774659 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,13270174 0,14767825 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,13270174 0,14760998 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,13270174 0,14754177 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,13270174 0,14747362 ! response to calcium ion GO:0051592 81 47 0,000 0,13538402 0,15038501 ! endosome transport GO:0016197 108 47 0,000 0,13538402 0,15031562 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,13538402 0,15024628 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,13538402 0,15017701 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,13538402 0,15010781 ! JNK cascade GO:0007254 91 47 0,000 0,13538402 0,15003866 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,13538402 0,14996959 ! protein homooligomerization GO:0051260 76 47 0,000 0,13538402 0,14990057 ! Notch signaling pathway GO:0007219 96 48 0,000 0,13805809 0,15279105 ! cellular component disassembly GO:0022411 86 48 0,000 0,13805809 0,15272081 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,13805809 0,15265062 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,13805809 0,1525805 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,13805809 0,15251045 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,13805809 0,15244046 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,14072397 0,15531279 ! regulation of action potential GO:0001508 95 49 0,000 0,14072397 0,15524158 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,14072397 0,15517043 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,14072397 0,15509935 ! regulation of ion transport GO:0043269 77 49 0,000 0,14072397 0,15502833 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,14072397 0,15495738 ! peptide metabolic process GO:0006518 76 49 0,000 0,14072397 0,1548865 ! response to temperature stimulus GO:0009266 76 49 0,000 0,14072397 0,15481567 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,14072397 0,15474492 ! endocrine system development GO:0035270 104 49 0,000 0,14072397 0,15467423 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,14072397 0,1546036 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,14072397 0,15453304 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,14072397 0,15446254 ! neuromuscular process GO:0050905 99 50 0,000 0,14338171 0,15730797 ! regulation of ossification GO:0030278 117 50 0,000 0,14338171 0,15723627 ! inner ear development GO:0048839 79 50 0,000 0,14338171 0,15716464 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,14338171 0,15709307 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,14338171 0,15702157 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,1460313 0,15985046 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,1460313 0,15977777 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,1460313 0,15970514 ! excretion GO:0007588 83 51 0,000 0,1460313 0,15963258 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,1460313 0,15956009 ! chromatin remodeling GO:0006338 109 51 0,000 0,1460313 0,15948766 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,1460313 0,1594153 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,1460313 0,159343 ! vesicle organization GO:0016050 107 51 0,000 0,1460313 0,15927077 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,1486728 0,16207827 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,1486728 0,16200487 ! membrane fusion GO:0006944 110 52 0,000 0,1486728 0,16193153 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,1486728 0,16185826 ! amino acid activation GO:0043038 92 52 0,000 0,1486728 0,16178505 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,1486728 0,16171191 ! synapse organization GO:0050808 85 52 0,000 0,1486728 0,16163884 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,1513062 0,16442761 ! RNA catabolic process GO:0006401 93 53 0,000 0,1513062 0,16435338 ! regulation of translational initiation GO:0006446 82 53 0,000 0,1513062 0,16427921 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,1513062 0,16420511 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,1513062 0,16413108 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,1513062 0,16405711 ! cell maturation GO:0048469 100 53 0,000 0,1513062 0,16398321 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,1513062 0,16390938 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,15393155 0,16667836 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,15393155 0,16660338 ! cell recognition GO:0008037 85 54 0,000 0,15393155 0,16652847 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,15393155 0,16645363 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,15393155 0,16637885 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,15393155 0,16630414 ! chloride transport GO:0006821 90 55 0,000 0,15654887 0,16905592 ! glucose catabolic process GO:0006007 82 55 0,000 0,15654887 0,16898007 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,15654887 0,1689043 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,15654887 0,16882859 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,15654887 0,16875295 ! gastrulation GO:0007369 112 55 0,000 0,15654887 0,16867738 ! RNA elongation GO:0006354 79 55 0,000 0,15654887 0,16860187 ! nuclear export GO:0051168 97 55 0,000 0,15654887 0,16852644 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,15654887 0,16845107 ! regulation of actin filament length GO:0030832 105 56 0,000 0,15915818 0,1711822 ! sensory perception of smell GO:0007608 80 56 0,000 0,15915818 0,17110571 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,15915818 0,17102929 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,15915818 0,17095293 ! proton transport GO:0015992 94 56 0,000 0,15915818 0,17087665 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,15915818 0,17080043 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,1617595 0,17351465 ! muscle fiber development GO:0048747 112 57 0,000 0,1617595 0,17343732 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,1617595 0,17336007 ! maintenance of location GO:0051235 118 57 0,000 0,1617595 0,17328288 ! hydrogen transport GO:0006818 97 58 0,000 0,16435286 0,17598263 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,16435286 0,17590435 ! regulation of endocytosis GO:0030100 91 58 0,000 0,16435286 0,17582613 ! adult behavior GO:0030534 99 58 0,000 0,16435286 0,17574799 ! positive regulation of secretion GO:0051047 95 59 0,000 0,16693828 0,17843336 ! regulation of cellular component size GO:0032535 109 59 0,000 0,16693828 0,17835413 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,16693828 0,17827496 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,16693828 0,17819587 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,16693828 0,17811685 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,16693828 0,1780379 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,16951579 0,18070668 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,16951579 0,18062665 ! regulation of heart contraction GO:0008016 110 60 0,000 0,16951579 0,18054669 ! camera-type eye development GO:0043010 116 60 0,000 0,16951579 0,1804668 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,16951579 0,18038699 ! kidney development GO:0001822 122 60 0,000 0,16951579 0,18030724 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,1720854 0,18295956 ! mesoderm development GO:0007498 119 61 0,000 0,1720854 0,18287875 ! tRNA processing GO:0008033 89 61 0,000 0,1720854 0,18279801 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,1720854 0,18271734 ! ear development GO:0043583 103 62 0,000 0,17464716 0,18535556 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,17464716 0,18527384 ! gonad development GO:0008406 98 62 0,000 0,17464716 0,18519218 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,17464716 0,1851106 ! regulation of mitosis GO:0007088 105 63 0,000 0,17720107 0,18773482 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,17720107 0,18765219 ! detection of external stimulus GO:0009581 91 63 0,000 0,17720107 0,18756963 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,17720107 0,18748715 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,17720107 0,18740473 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,17974716 0,19001392 ! cell redox homeostasis GO:0045454 102 64 0,000 0,17974716 0,18993047 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,17974716 0,18984709 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,17974716 0,18976379 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,18228546 0,19235913 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,18228546 0,1922748 ! germ cell development GO:0007281 118 65 0,000 0,18228546 0,19219054 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,18481599 0,19477323 ! actin filament organization GO:0007015 148 66 0,000 0,18481599 0,19468795 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,18481599 0,19460275 ! extracellular matrix organization GO:0030198 133 66 0,000 0,18481599 0,19451762 ! secondary metabolic process GO:0019748 116 66 0,000 0,18481599 0,19443256 ! developmental maturation GO:0021700 116 66 0,000 0,18481599 0,19434758 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,18733877 0,19691441 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,18733877 0,19682842 ! chromosome segregation GO:0007059 113 67 0,000 0,18733877 0,19674251 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,18733877 0,19665667 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,18733877 0,19657091 ! hexose catabolic process GO:0019320 104 67 0,000 0,18733877 0,19648522 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,18733877 0,1963996 ! amino acid transport GO:0006865 125 68 0,000 0,18985383 0,19894962 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,18985383 0,198863 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,18985383 0,19877647 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,18985383 0,19869 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,19236119 0,20122653 ! urogenital system development GO:0001655 137 69 0,000 0,19236119 0,20113908 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,19236119 0,2010517 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,19236119 0,2009644 ! antigen processing and presentation GO:0019882 104 69 0,000 0,19236119 0,20087718 ! amine catabolic process GO:0009310 117 71 0,000 0,1973529 0,20600046 ! reproductive structure development GO:0048608 113 71 0,000 0,1973529 0,20591113 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,1973529 0,20582188 ! regulation of immune effector process GO:0002697 137 71 0,000 0,1973529 0,2057327 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,19983729 0,20823236 ! carbohydrate transport GO:0008643 110 72 0,000 0,19983729 0,20814222 ! learning or memory GO:0007611 147 73 0,000 0,20231408 0,21063076 ! regulation of blood pressure GO:0008217 125 73 0,000 0,20231408 0,21053965 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,20231408 0,21044863 ! axon guidance GO:0007411 139 73 0,000 0,20231408 0,21035768 ! fertilization GO:0009566 90 73 0,000 0,20231408 0,21026682 ! transition metal ion transport GO:0000041 126 74 0,000 0,20478329 0,21274119 ! neurotransmitter transport GO:0006836 123 74 0,000 0,20478329 0,21264937 ! meiosis GO:0007126 121 74 0,000 0,20478329 0,21255763 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,20478329 0,21246597 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,20478329 0,21237439 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,20724493 0,21483468 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,20724493 0,21474216 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,20724493 0,21464972 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,20724493 0,21455736 ! meiotic cell cycle GO:0051321 122 75 0,000 0,20724493 0,21446508 ! rhythmic process GO:0048511 128 75 0,000 0,20724493 0,21437287 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,20969904 0,21681817 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,20969904 0,21672503 ! defense response to bacterium GO:0042742 89 76 0,000 0,20969904 0,21663198 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,20969904 0,216539 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,20969904 0,21644611 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,21214562 0,21887752 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,21214562 0,2187837 ! blood coagulation GO:0007596 146 78 0,000 0,21458472 0,2212043 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,21458472 0,22110957 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,21458472 0,22101491 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,21701635 0,22342376 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,21701635 0,2233282 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,21701635 0,22323272 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,21701635 0,22313732 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,21944053 0,22553349 ! response to metal ion GO:0010038 140 80 0,000 0,21944053 0,22543719 ! muscle cell differentiation GO:0042692 159 80 0,000 0,21944053 0,22534098 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,21944053 0,22524484 ! inorganic anion transport GO:0015698 138 80 0,000 0,21944053 0,22514879 ! digestion GO:0007586 112 81 0,000 0,22185728 0,22753138 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,22185728 0,22743443 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,22185728 0,22733757 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,22185728 0,22724079 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,22426663 0,22961086 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,22426663 0,22951319 ! response to nutrient GO:0007584 125 82 0,000 0,22426663 0,22941561 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,22426663 0,22931811 ! regulation of lyase activity GO:0051339 160 83 0,000 0,2266686 0,23167573 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,22906322 0,23402382 ! hemostasis GO:0007599 158 84 0,000 0,22906322 0,23392449 ! negative regulation of transport GO:0051051 153 84 0,000 0,22906322 0,23382524 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,22906322 0,23372608 ! response to unfolded protein GO:0006986 131 85 0,000 0,23145049 0,23606184 ! nucleosome assembly GO:0006334 122 85 0,000 0,23145049 0,23596182 ! amine biosynthetic process GO:0009309 138 86 0,000 0,23383046 0,2382872 ! response to inorganic substance GO:0010035 153 86 0,000 0,23383046 0,23818632 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,23383046 0,23808552 ! chromatin assembly GO:0031497 124 86 0,000 0,23383046 0,23798481 ! alcohol catabolic process GO:0046164 130 86 0,000 0,23383046 0,23788418 ! amine transport GO:0015837 155 86 0,000 0,23383046 0,23778364 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,23620313 0,24009495 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,23620313 0,23999355 ! regulation of protein transport GO:0051223 154 87 0,000 0,23620313 0,23989225 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,23856854 0,24219236 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,23856854 0,24209022 ! regulation of neurological system process GO:0031644 148 88 0,000 0,23856854 0,24198815 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,23856854 0,24188618 ! cellular defense response GO:0006968 114 89 0,000 0,2409267 0,24417423 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,2409267 0,24407142 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,24327763 0,24634932 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,24327763 0,24624568 ! sex differentiation GO:0007548 145 90 0,000 0,24327763 0,24614213 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,24327763 0,24603866 ! sterol metabolic process GO:0016125 152 91 0,000 0,24562136 0,24830462 ! response to protein stimulus GO:0051789 149 91 0,000 0,24562136 0,24820033 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,24562136 0,24809613 ! nucleosome organization GO:0034728 138 92 0,000 0,24795791 0,25035112 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,24795791 0,25024611 ! vitamin metabolic process GO:0006766 139 92 0,000 0,24795791 0,25014118 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,2502873 0,25238526 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,2502873 0,25227953 ! regulation of membrane potential GO:0042391 164 93 0,000 0,2502873 0,25217388 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,25260955 0,2544071 ! female pregnancy GO:0007565 164 94 0,000 0,25260955 0,25430066 ! transcription initiation GO:0006352 153 94 0,000 0,25260955 0,2541943 ! regulation of T cell activation GO:0050863 158 94 0,000 0,25260955 0,25408803 ! forebrain development GO:0030900 188 95 0,000 0,25492468 0,25630956 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,25492468 0,2562025 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,25723272 0,25841417 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,25723272 0,25830632 ! detection of stimulus GO:0051606 151 96 0,000 0,25723272 0,25819855 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,25953369 0,26039953 ! protein ubiquitination GO:0016567 217 97 0,000 0,25953369 0,26029098 ! hormone metabolic process GO:0042445 157 97 0,000 0,25953369 0,26018253 ! regulation of protein localization GO:0032880 176 97 0,000 0,25953369 0,26007416 ! response to virus GO:0009615 160 98 0,000 0,26182761 0,26226362 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,26182761 0,26215448 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,26182761 0,26204544 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,26411449 0,26422431 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,26411449 0,26411449