pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1098-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 4,000 2,293E-08 5,603E-05 ! nuclear migration GO:0007097 13 6 2,000 4,978E-07 6,08E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 4,978E-07 4,053E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipid kinase activity GO:0043550 17 8 2,000 1,388E-06 8,476E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 1,388E-06 6,78E-04 ! macrophage differentiation GO:0030225 15 9 2,000 2,077E-06 8,457E-04 ! protein heterooligomerization GO:0051291 17 10 2,000 2,961E-06 1,033E-03 ! nucleus localization GO:0051647 22 11 2,000 4,063E-06 1,241E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 5,405E-06 1,467E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 1,066E-05 2,605E-03 ! filopodium assembly GO:0046847 42 17 2,000 1,653E-05 3,671E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,979E-05 4,029E-03 ! microspike assembly GO:0030035 46 18 2,000 1,979E-05 3,719E-03 ! response to UV GO:0009411 120 55 3,000 2,184E-05 3,81E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 3,205E-05 5,22E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 5,495E-05 8,39E-03 ! interaction with host GO:0051701 66 25 2,000 5,495E-05 7,897E-03 ! protein tetramerization GO:0051262 57 25 2,000 5,495E-05 7,458E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 6,198E-05 7,97E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 6,958E-05 8,499E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 6,958E-05 8,095E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 7,776E-05 8,635E-03 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 7,776E-05 8,26E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 8,594E-05 8,748E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 8,594E-05 8,398E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 8,594E-05 8,075E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 8,594E-05 7,776E-03 ! G2/M transition checkpoint GO:0031576 8 5 1,000 8,594E-05 7,498E-03 GO:0031572|G2/M transition DNA damage checkpoint, ! protein insertion into membrane GO:0051205 17 5 1,000 8,594E-05 7,24E-03 ! protein oligomerization GO:0051259 149 79 3,000 9,111E-05 7,419E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 9,596E-05 7,562E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 1,06E-04 8,094E-03 ! response to drug GO:0042493 149 83 3,000 1,104E-04 8,175E-03 ! negative regulation of growth GO:0045926 168 85 3,000 1,211E-04 8,703E-03 ! negative regulation of multicellular organism growth GO:0040015 9 6 1,000 1,287E-04 8,98E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 1,287E-04 8,731E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 1,402E-04 9,259E-03 ! DNA damage checkpoint GO:0000077 78 35 2,000 1,53E-04 9,839E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,715E-04 0,01074431 ! regulation of helicase activity GO:0051095 16 7 1,000 1,798E-04 0,01097963 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,798E-04 0,01071183 ! male sex determination GO:0030238 15 7 1,000 1,798E-04 0,01045679 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 1,798E-04 0,01021361 ! B cell lineage commitment GO:0002326 21 7 1,000 1,798E-04 9,981E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,798E-04 9,76E-03 ! DNA integrity checkpoint GO:0031570 82 38 2,000 1,96E-04 0,01040914 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 1,96E-04 0,01018767 ! leukocyte differentiation GO:0002521 232 98 3,000 2,098E-04 0,010679 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 2,098E-04 0,01046106 ! mitotic cell cycle checkpoint GO:0007093 76 39 2,000 2,119E-04 0,01035221 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,392E-04 0,0114598 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,392E-04 0,01123942 ! ER overload response GO:0006983 13 8 1,000 2,392E-04 0,01102736 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 2,392E-04 0,01082315 ! response to tumor cell GO:0002347 16 8 1,000 2,392E-04 0,01062636 ! regulation of respiratory burst GO:0060263 12 8 1,000 2,392E-04 0,01043661 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 2,461E-04 0,01054687 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,07E-04 0,01293079 ! regulation of glycolysis GO:0006110 20 9 1,000 3,07E-04 0,01271163 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 3,07E-04 0,01249976 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 3,248E-04 0,01300675 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 3,248E-04 0,01279696 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 3,467E-04 0,01344363 ! response to insulin stimulus GO:0032868 98 47 2,000 3,695E-04 0,01410559 ! regulation of developmental growth GO:0048638 16 10 1,000 3,83E-04 0,01439498 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 3,83E-04 0,01417688 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 3,83E-04 0,01396528 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 3,83E-04 0,01375991 ! induction of an organ GO:0001759 17 10 1,000 3,83E-04 0,01356049 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 3,83E-04 0,01336677 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 4,672E-04 0,016076 ! keratinocyte proliferation GO:0043616 19 11 1,000 4,672E-04 0,01585272 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 4,672E-04 0,01563556 ! regulation of intracellular pH GO:0051453 21 11 1,000 4,672E-04 0,01542427 ! regulation of smoothened signaling pathway GO:0008589 27 11 1,000 4,672E-04 0,01521861 ! DNA methylation GO:0006306 19 11 1,000 4,672E-04 0,01501837 GO:0006305|DNA alkylation, ! regulation of embryonic development GO:0045995 35 11 1,000 4,672E-04 0,01482332 ! regulation of cell projection organization GO:0031344 135 51 2,000 4,705E-04 0,01473746 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 5,596E-04 0,01730423 ! virus-host interaction GO:0019048 30 12 1,000 5,596E-04 0,01708793 ! regulation of B cell proliferation GO:0030888 22 12 1,000 5,596E-04 0,01687697 ! entry into host cell GO:0030260 34 12 1,000 5,596E-04 0,01667115 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 5,596E-04 0,01647029 ! peptidyl-lysine modification GO:0018205 21 12 1,000 5,596E-04 0,01627422 ! developmental induction GO:0031128 22 12 1,000 5,596E-04 0,01608276 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 5,596E-04 0,01589575 ! regulation of DNA replication GO:0006275 105 56 2,000 6,197E-04 0,01740027 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 6,527E-04 0,01811941 ! response to X-ray GO:0010165 28 13 1,000 6,6E-04 0,01811766 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 6,6E-04 0,01791635 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 6,6E-04 0,01771947 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 6,6E-04 0,01752686 ! positive regulation of cell migration GO:0030335 137 58 2,000 6,868E-04 0,01804178 ! establishment of organelle localization GO:0051656 122 59 2,000 7,221E-04 0,01876589 ! cell-cell junction assembly GO:0007043 32 14 1,000 7,686E-04 0,01976412 ! regulation of cellular pH GO:0030641 27 14 1,000 7,686E-04 0,01955824 ! response to gamma radiation GO:0010332 30 14 1,000 7,686E-04 0,01935661 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 7,686E-04 0,01915909 ! viral reproductive process GO:0022415 132 62 2,000 8,346E-04 0,02059644 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 8,346E-04 0,02039047 ! regulation of protein complex assembly GO:0043254 132 63 2,000 8,745E-04 0,02115272 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 8,851E-04 0,02119879 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 8,851E-04 0,02099298 ! G1/S transition checkpoint GO:0031575 37 15 1,000 8,851E-04 0,02079112 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 9,156E-04 0,02130196 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 9,156E-04 0,021101 ! positive regulation of cell motion GO:0051272 157 65 2,000 9,578E-04 0,02186846 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 1,001E-03 0,0226492 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,01E-03 0,02262764 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,01E-03 0,02242194 ! negative regulation of cell growth GO:0030308 142 67 2,000 1,046E-03 0,02302078 ! myeloid cell differentiation GO:0030099 126 67 2,000 1,046E-03 0,02281524 ! viral reproduction GO:0016032 142 68 2,000 1,092E-03 0,02360651 ! cell projection assembly GO:0030031 138 68 2,000 1,092E-03 0,02339943 ! negative regulation of cell size GO:0045792 144 69 2,000 1,139E-03 0,02419855 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 1,139E-03 0,02398994 ! lung development GO:0030324 165 69 2,000 1,139E-03 0,02378489 ! negative regulation of kinase activity GO:0033673 145 70 2,000 1,188E-03 0,0245867 ! cell cycle checkpoint GO:0000075 145 71 2,000 1,237E-03 0,02540134 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 1,282E-03 0,0261048 ! respiratory tube development GO:0030323 171 72 2,000 1,288E-03 0,026012 ! negative regulation of transferase activity GO:0051348 155 74 2,000 1,394E-03 0,02792171 ! respiratory system development GO:0060541 175 74 2,000 1,394E-03 0,02769471 ! organelle localization GO:0051640 155 74 2,000 1,394E-03 0,02747136 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 1,43E-03 0,027955 ! pigmentation during development GO:0048066 42 19 1,000 1,43E-03 0,02773313 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,586E-03 0,03051312 ! protein amino acid acetylation GO:0006473 41 20 1,000 1,586E-03 0,03027473 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 1,586E-03 0,03004004 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 1,586E-03 0,02980897 ! cell-cell junction organization GO:0045216 43 20 1,000 1,586E-03 0,02958142 ! lipid phosphorylation GO:0046834 43 21 1,000 1,75E-03 0,03238512 ! positive regulation of inflammatory response GO:0050729 41 21 1,000 1,75E-03 0,03214163 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 1,75E-03 0,03190176 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 1,921E-03 0,03476499 ! cellular response to starvation GO:0009267 37 22 1,000 1,921E-03 0,03450936 ! cell aging GO:0007569 48 22 1,000 1,921E-03 0,03425747 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 1,921E-03 0,03400923 ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,921E-03 0,03376456 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 2,075E-03 0,03621319 ! positive regulation of DNA replication GO:0045740 44 23 1,000 2,1E-03 0,03638557 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 2,1E-03 0,03612933 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 2,1E-03 0,03587668 ! DNA modification GO:0006304 36 23 1,000 2,1E-03 0,03562753 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 2,287E-03 0,03852413 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 2,287E-03 0,03826027 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 2,287E-03 0,03799999 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 2,287E-03 0,03774324 ! sex determination GO:0007530 48 24 1,000 2,287E-03 0,03748993 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 2,287E-03 0,03723999 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 2,287E-03 0,03699337 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 2,481E-03 0,03986885 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 2,481E-03 0,03960827 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 2,481E-03 0,03935107 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 2,481E-03 0,03909719 ! negative regulation of DNA replication GO:0008156 45 25 1,000 2,481E-03 0,03884657 ! initiation of viral infection GO:0019059 60 26 1,000 2,682E-03 0,04173536 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 2,682E-03 0,04147121 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 2,682E-03 0,04121039 ! negative regulation of cell development GO:0010721 83 26 1,000 2,682E-03 0,04095282 GO:0050768|negative regulation of neurogenesis, ! mitochondrial membrane organization GO:0007006 60 27 1,000 2,891E-03 0,04386987 ! response to starvation GO:0042594 47 27 1,000 2,891E-03 0,04359907 ! cellular response to oxidative stress GO:0034599 43 27 1,000 2,891E-03 0,04333159 ! cellular response to nutrient levels GO:0031669 45 27 1,000 2,891E-03 0,04306737 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 3,02E-03 0,04470895 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 3,108E-03 0,04573341 ! protein amino acid acylation GO:0043543 59 28 1,000 3,108E-03 0,04545956 ! base-excision repair GO:0006284 41 28 1,000 3,108E-03 0,04518897 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 3,331E-03 0,04815642 ! somitogenesis GO:0001756 52 29 1,000 3,331E-03 0,04787315 ! complement activation, classical pathway GO:0006958 51 30 1,000 3,562E-03 0,05089478 ! regulation of B cell activation GO:0050864 55 30 1,000 3,562E-03 0,05059888 ! cell junction assembly GO:0034329 85 31 1,000 3,801E-03 0,05367256 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 4,046E-03 0,05681244 ! positive regulation of catabolic process GO:0009896 72 32 1,000 4,046E-03 0,0564878 ! regulation of pH GO:0006885 56 33 1,000 4,299E-03 0,05967577 ! cholesterol homeostasis GO:0042632 60 33 1,000 4,299E-03 0,05933862 GO:0055092|sterol homeostasis, ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 4,299E-03 0,05900525 ! response to ionizing radiation GO:0010212 74 33 1,000 4,299E-03 0,05867562 ! cell fate specification GO:0001708 56 34 1,000 4,559E-03 0,06187754 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 4,826E-03 0,06513992 ! calcium-mediated signaling GO:0019722 67 35 1,000 4,826E-03 0,06478201 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 5,1E-03 0,06808706 ! cytokine production GO:0001816 68 36 1,000 5,1E-03 0,06771703 ! cell junction organization GO:0034330 96 37 1,000 5,381E-03 0,0710631 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 5,669E-03 0,07446475 ! neural tube formation GO:0001841 79 38 1,000 5,669E-03 0,07406654 ! carbohydrate homeostasis GO:0033500 59 39 1,000 5,964E-03 0,07750605 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 5,964E-03 0,07709596 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 6,266E-03 0,08057185 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 1,000 6,266E-03 0,08015 ! lipid homeostasis GO:0055088 75 40 1,000 6,266E-03 0,07973256 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 6,575E-03 0,08322736 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 6,575E-03 0,08279835 ! T cell differentiation GO:0030217 93 42 1,000 6,891E-03 0,08632678 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 6,891E-03 0,08588634 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 7,213E-03 0,08944708 GO:0090047|positive regulation of transcription regulator activity, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 7,213E-03 0,08899533 ! segmentation GO:0035282 78 43 1,000 7,213E-03 0,08854812 ! response to reactive oxygen species GO:0000302 75 44 1,000 7,542E-03 0,09212418 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 7,542E-03 0,09166585 ! double-strand break repair GO:0006302 85 44 1,000 7,542E-03 0,09121206 ! biopolymer methylation GO:0043414 91 45 1,000 7,878E-03 0,09480247 ! B cell differentiation GO:0030183 124 45 1,000 7,878E-03 0,09433776 ! pigmentation GO:0043473 103 46 1,000 8,22E-03 0,09795694 ! cell growth GO:0016049 90 46 1,000 8,22E-03 0,09748142 ! neural tube development GO:0021915 91 47 1,000 8,569E-03 0,10112825 ! positive regulation of cell cycle GO:0045787 96 48 1,000 8,924E-03 0,10481694 ! positive regulation of defense response GO:0031349 88 48 1,000 8,924E-03 0,10431542 ! mitochondrial transport GO:0006839 94 48 1,000 8,924E-03 0,10381868 ! positive regulation of DNA binding GO:0043388 83 48 1,000 8,924E-03 0,10332665 ! regulation of inflammatory response GO:0050727 84 48 1,000 8,924E-03 0,10283926 ! methylation GO:0032259 97 48 1,000 8,924E-03 0,10235645 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 9,286E-03 0,1060103 ! activation of caspase activity GO:0006919 95 50 1,000 9,655E-03 0,10970365 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 9,655E-03 0,10919577 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 9,655E-03 0,10869256 ! viral infectious cycle GO:0019058 104 51 1,000 0,0100295 0,11239483 ! positive regulation of binding GO:0051099 88 52 1,000 0,01041075 0,11613454 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,01041075 0,11560665 ! histone modification GO:0016570 104 52 1,000 0,01041075 0,11508354 ! positive regulation of growth GO:0045927 96 53 1,000 0,01079835 0,11883046 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,01079835 0,11829758 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,01079835 0,11776947 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,01119225 0,12152297 GO:0010863|positive regulation of phospholipase C activity, ! covalent chromatin modification GO:0016569 115 54 1,000 0,01119225 0,12098526 ! regulation of cell shape GO:0008360 142 54 1,000 0,01119225 0,12045228 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,01119225 0,11992398 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,01159242 0,12366937 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,01159242 0,12313168 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,01241141 0,13126003 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,01241141 0,13069425 ! heart morphogenesis GO:0003007 105 57 1,000 0,01241141 0,13013333 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,01241141 0,12957721 ! aging GO:0007568 112 58 1,000 0,01283014 0,13337888 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,01283014 0,13281372 ! lipid modification GO:0030258 112 60 1,000 0,0136859 0,14107452 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,01412285 0,1449669 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01468424 0,15009872 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01468424 0,14947331 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01468424 0,14885308 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01468424 0,14823799 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01468424 0,14762796 ! neuron fate determination GO:0048664 7 5 0,000 0,01468424 0,14702292 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01468424 0,14642283 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01468424 0,14582762 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01468424 0,14523722 ! polyol transport GO:0015791 12 5 0,000 0,01468424 0,14465159 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01468424 0,14407066 ! response to superoxide GO:0000303 10 5 0,000 0,01468424 0,14349437 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01468424 0,14292268 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01468424 0,14235553 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01468424 0,14179286 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01468424 0,14123462 ! female meiosis GO:0007143 10 5 0,000 0,01468424 0,14068076 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01468424 0,14013122 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01468424 0,13958597 ! hypothalamus development GO:0021854 9 5 0,000 0,01468424 0,13904494 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01468424 0,13850808 ! cobalt ion transport GO:0006824 11 5 0,000 0,01468424 0,13797536 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01468424 0,13744672 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01468424 0,13692211 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01468424 0,1364015 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01468424 0,13588482 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01468424 0,13537205 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01468424 0,13486313 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01468424 0,13435803 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01468424 0,13385669 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01468424 0,13335908 ! transposition GO:0032196 9 5 0,000 0,01468424 0,13286516 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01468424 0,13237488 ! negative chemotaxis GO:0050919 16 5 0,000 0,01468424 0,13188821 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01468424 0,1314051 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01468424 0,13092552 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01468424 0,13044943 ! behavioral response to pain GO:0048266 10 5 0,000 0,01468424 0,12997679 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01468424 0,12950756 ! Notch receptor processing GO:0007220 11 5 0,000 0,01468424 0,1290417 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01468424 0,12857919 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01468424 0,12811998 ! micturition GO:0060073 9 5 0,000 0,01468424 0,12766403 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01468424 0,12721132 ! copulation GO:0007620 9 5 0,000 0,01468424 0,12676181 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01468424 0,12631547 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01468424 0,12587226 ! bioluminescence GO:0008218 9 5 0,000 0,01468424 0,12543214 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01468424 0,1249951 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01468424 0,12456109 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01468424 0,12413008 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01468424 0,12370205 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01468424 0,12327695 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01468424 0,12285477 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01468424 0,12243547 ! grooming behavior GO:0007625 6 5 0,000 0,01468424 0,12201903 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01468424 0,1216054 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01468424 0,12119457 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01468424 0,12078651 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01468424 0,12038119 ! response to protozoan GO:0001562 13 5 0,000 0,01468424 0,11997857 ! lymph vessel development GO:0001945 10 5 0,000 0,01468424 0,11957864 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01468424 0,11918137 ! endochondral ossification GO:0001958 17 5 0,000 0,01468424 0,11878673 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01468424 0,1183947 ! single strand break repair GO:0000012 8 5 0,000 0,01468424 0,11800524 ! parathyroid gland development GO:0060017 14 5 0,000 0,01468424 0,11761834 ! anagen GO:0042640 7 5 0,000 0,01468424 0,11723397 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01468424 0,1168521 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01468424 0,11647271 ! cytokine secretion GO:0050663 15 5 0,000 0,01468424 0,11609577 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01468424 0,11572127 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01468424 0,11534918 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01468424 0,11497947 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01468424 0,11461212 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01468424 0,11424711 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01468424 0,11388442 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01468424 0,11352403 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01468424 0,11316591 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01468424 0,11281004 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01468424 0,11245641 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01468424 0,11210498 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01468424 0,11175574 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01468424 0,11140868 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01468424 0,11106376 ! microvillus organization GO:0032528 8 5 0,000 0,01468424 0,11072097 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01468424 0,11038029 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01468424 0,1100417 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01468424 0,10970518 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01468424 0,10937071 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01468424 0,10903828 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01468424 0,10870786 ! polyol catabolic process GO:0046174 9 5 0,000 0,01468424 0,10837944 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01468424 0,10805299 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01468424 0,10772851 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01468424 0,10740597 ! muscle cell migration GO:0014812 8 5 0,000 0,01468424 0,10708535 ! mitochondrial fission GO:0000266 8 5 0,000 0,01468424 0,10676665 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01468424 0,10644983 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01468424 0,10613489 ! mRNA transcription GO:0009299 10 5 0,000 0,01468424 0,10582181 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01468424 0,10551057 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01468424 0,10520115 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01468424 0,10489355 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01468424 0,10458774 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01468424 0,1042837 ! monocyte activation GO:0042117 10 5 0,000 0,01468424 0,10398143 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01468424 0,10368091 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01468424 0,10338211 ! response to food GO:0032094 6 5 0,000 0,01468424 0,10308504 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01468424 0,10278967 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01468424 0,10249598 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01468424 0,10220397 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01468424 0,10191362 ! forebrain neuron development GO:0021884 13 5 0,000 0,01468424 0,10162491 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01468424 0,10133783 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01468424 0,10105238 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01468424 0,10076852 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01468424 0,10048626 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01468424 0,10020557 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01468424 0,09992644 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01468424 0,09964887 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01468424 0,09937284 ! lipid glycosylation GO:0030259 7 5 0,000 0,01468424 0,09909832 ! nucleobase transport GO:0015851 6 5 0,000 0,01468424 0,09882533 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01468424 0,09855383 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01468424 0,09828382 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01468424 0,09801528 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01468424 0,09774821 ! basic amino acid transport GO:0015802 12 5 0,000 0,01468424 0,09748259 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01468424 0,09721841 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01468424 0,09695566 ! actin nucleation GO:0045010 11 5 0,000 0,01468424 0,09669432 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01468424 0,09643439 ! depurination GO:0045007 5 5 0,000 0,01468424 0,09617585 ! depyrimidination GO:0045008 10 5 0,000 0,01468424 0,0959187 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01468424 0,09566292 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01468424 0,09540849 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01468424 0,09515542 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01468424 0,09490369 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01468424 0,09465328 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01468424 0,09440419 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01468424 0,09415641 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01468424 0,09390993 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01468424 0,09366473 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01468424 0,09342082 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01468424 0,09317816 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01468424 0,09293677 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01468424 0,09269662 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01468424 0,09245772 ! response to arsenic GO:0046685 11 5 0,000 0,01468424 0,09222003 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01468424 0,09198357 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01468424 0,09174832 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01468424 0,09151427 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01468424 0,09128141 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01468424 0,09104973 ! response to mercury ion GO:0046689 8 5 0,000 0,01468424 0,09081922 ! response to cadmium ion GO:0046686 7 5 0,000 0,01468424 0,09058988 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01468424 0,0903617 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01468424 0,09013466 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01468424 0,08990876 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01468424 0,08968398 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01468424 0,08946033 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01468424 0,08923779 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01468424 0,08901636 ! decidualization GO:0046697 11 5 0,000 0,01468424 0,08879602 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01468424 0,08857677 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01468424 0,0883586 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01468424 0,08814151 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01468424 0,08792547 ! embryonic cleavage GO:0040016 6 5 0,000 0,01468424 0,0877105 ! peroxisome fission GO:0016559 5 5 0,000 0,01468424 0,08749657 ! histone demethylation GO:0016577 13 5 0,000 0,01468424 0,08728368 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01468424 0,08707183 ! mitotic recombination GO:0006312 9 5 0,000 0,01468424 0,086861 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01468424 0,08665119 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01468424 0,08644239 ! metaphase plate congression GO:0051310 7 5 0,000 0,01468424 0,0862346 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01468424 0,0860278 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01468424 0,08582199 ! enteric nervous system development GO:0048484 8 5 0,000 0,01468424 0,08561717 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01468424 0,08541332 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01468424 0,08521044 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01468424 0,08500852 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01468424 0,08480755 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01468424 0,08460753 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01468424 0,08440846 ! B cell homeostasis GO:0001782 13 5 0,000 0,01468424 0,08421031 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01468424 0,0840131 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01468424 0,08381681 ! metaphase GO:0051323 11 5 0,000 0,01468424 0,08362143 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01468424 0,08342696 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01468424 0,0832334 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01468424 0,08304073 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01468424 0,08284895 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01468424 0,08265805 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01468424 0,08246803 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01468424 0,08227888 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01468424 0,0820906 ! response to redox state GO:0051775 6 5 0,000 0,01468424 0,08190318 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01468424 0,08171661 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01468424 0,08153089 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01468424 0,08134602 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01468424 0,08116198 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01468424 0,08097877 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01468424 0,08079638 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01468424 0,08061482 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01468424 0,08043407 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01468424 0,08025412 ! striatum development GO:0021756 14 5 0,000 0,01468424 0,08007499 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01468424 0,07989664 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01468424 0,0797191 ! glial cell migration GO:0008347 10 5 0,000 0,01468424 0,07954234 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01468424 0,07936636 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01468424 0,07919116 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01468424 0,07901673 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01468424 0,07884306 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01468424 0,07867016 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01468424 0,07849802 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01468424 0,07832662 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01468424 0,07815598 ! neuroprotection GO:0043526 8 5 0,000 0,01468424 0,07798607 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01468424 0,07781691 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01468424 0,07764847 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01468424 0,07748076 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01468424 0,07731378 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01468424 0,07714751 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01468424 0,07698196 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01468424 0,07681712 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01468424 0,07665298 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01468424 0,07648954 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01468424 0,07632679 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01468424 0,07616474 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01468424 0,07600338 ! spindle assembly GO:0051225 6 5 0,000 0,01468424 0,07584269 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01468424 0,07568269 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01468424 0,07552335 ! protein palmitoylation GO:0018345 12 5 0,000 0,01468424 0,07536469 ! drug metabolic process GO:0017144 7 5 0,000 0,01468424 0,07520669 ! stem cell division GO:0017145 11 5 0,000 0,01468424 0,07504936 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01468424 0,07489268 ! organ regeneration GO:0031100 7 5 0,000 0,01468424 0,07473665 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01468424 0,07458128 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01468424 0,07442654 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,01593018 0,08057441 ! activation of MAPK activity GO:0000187 124 67 1,000 0,01686904 0,08514684 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,01686904 0,08497128 GO:0035113|embryonic appendage morphogenesis, ! regulation of lipase activity GO:0060191 137 68 1,000 0,01734714 0,0871997 ! adaptive immune response GO:0002250 126 68 1,000 0,01734714 0,08702065 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,01734714 0,08684233 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01759535 0,08790481 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01759535 0,08772541 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01759535 0,08754674 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01759535 0,0873688 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01759535 0,08719158 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01759535 0,08701508 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01759535 0,08683929 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01759535 0,08666421 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01759535 0,08648984 ! response to oxygen radical GO:0000305 11 6 0,000 0,01759535 0,08631616 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01759535 0,08614319 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01759535 0,0859709 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01759535 0,0857993 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01759535 0,08562839 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01759535 0,08545815 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01759535 0,08528859 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01759535 0,0851197 ! forebrain regionalization GO:0021871 9 6 0,000 0,01759535 0,08495148 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01759535 0,08478393 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01759535 0,08461703 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01759535 0,08445079 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01759535 0,0842852 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01759535 0,08412025 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01759535 0,08395596 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01759535 0,0837923 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01759535 0,08362928 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01759535 0,08346689 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01759535 0,08330514 ! malate metabolic process GO:0006108 13 6 0,000 0,01759535 0,083144 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01759535 0,08298349 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01759535 0,0828236 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01759535 0,08266433 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01759535 0,08250566 ! protein refolding GO:0042026 15 6 0,000 0,01759535 0,08234761 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01759535 0,08219015 ! opsonization GO:0008228 8 6 0,000 0,01759535 0,0820333 ! mating behavior GO:0007617 7 6 0,000 0,01759535 0,08187705 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01759535 0,08172139 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01759535 0,08156632 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01759535 0,08141184 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01759535 0,08125794 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01759535 0,08110462 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01759535 0,08095188 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01759535 0,08079972 ! toxin metabolic process GO:0009404 11 6 0,000 0,01759535 0,08064812 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01759535 0,0804971 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01759535 0,08034664 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01759535 0,08019674 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01759535 0,08004739 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01759535 0,07989861 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01759535 0,07975037 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01759535 0,07960269 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01759535 0,07945555 ! thymic T cell selection GO:0045061 16 6 0,000 0,01759535 0,07930895 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01759535 0,07916289 ! protein lipoylation GO:0009249 10 6 0,000 0,01759535 0,07901737 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01759535 0,07887239 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01759535 0,07872793 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01759535 0,078584 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01759535 0,0784406 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01759535 0,07829772 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01759535 0,07815536 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01759535 0,07801352 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01759535 0,07787219 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01759535 0,07773137 ! hyperosmotic response GO:0006972 10 6 0,000 0,01759535 0,07759107 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01759535 0,07745126 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01759535 0,07731196 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01759535 0,07717316 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01759535 0,07703486 ! urea metabolic process GO:0019627 7 6 0,000 0,01759535 0,07689705 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01759535 0,07675973 ! neutrophil activation GO:0042119 7 6 0,000 0,01759535 0,07662291 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01759535 0,07648657 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01759535 0,07635071 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01759535 0,07621534 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01759535 0,07608044 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01759535 0,07594602 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01759535 0,07581208 ! neuron apoptosis GO:0051402 15 6 0,000 0,01759535 0,07567861 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01759535 0,07554561 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01759535 0,07541307 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01759535 0,075281 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01759535 0,07514939 ! carnitine transport GO:0015879 10 6 0,000 0,01759535 0,07501824 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01759535 0,07488754 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01759535 0,0747573 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01759535 0,07462752 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01759535 0,07449818 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01759535 0,07436929 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01759535 0,07424085 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01759535 0,07411284 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01759535 0,07398528 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01759535 0,07385816 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01759535 0,07373148 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01759535 0,07360522 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01759535 0,0734794 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01759535 0,07335401 ! response to UV-C GO:0010225 14 6 0,000 0,01759535 0,07322905 ! astrocyte development GO:0014002 16 6 0,000 0,01759535 0,07310451 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01759535 0,07298039 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01759535 0,0728567 ! interaction with symbiont GO:0051702 14 6 0,000 0,01759535 0,07273342 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01759535 0,07261056 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01759535 0,07248811 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01759535 0,07236608 ! response to copper ion GO:0046688 10 6 0,000 0,01759535 0,07224445 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01759535 0,07212324 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01759535 0,07200243 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01759535 0,07188202 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01759535 0,07176202 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01759535 0,07164242 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01759535 0,07152321 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01759535 0,0714044 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01759535 0,07128599 ! hair follicle maturation GO:0048820 8 6 0,000 0,01759535 0,07116796 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01759535 0,07105033 ! Schwann cell development GO:0014044 15 6 0,000 0,01759535 0,07093309 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01759535 0,07081623 ! response to pheromone GO:0019236 6 6 0,000 0,01759535 0,07069975 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01759535 0,07058366 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01759535 0,07046795 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01759535 0,07035262 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01759535 0,07023766 ! subpallium development GO:0021544 15 6 0,000 0,01759535 0,07012308 ! neural tube patterning GO:0021532 8 6 0,000 0,01759535 0,07000888 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01759535 0,06989504 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01759535 0,06978157 ! G2 phase GO:0051319 16 6 0,000 0,01759535 0,06966848 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01759535 0,06955574 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01759535 0,06944338 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01759535 0,06933137 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01759535 0,06921973 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01759535 0,06910844 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01759535 0,06899751 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01759535 0,06888694 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01759535 0,06877672 ! receptor internalization GO:0031623 11 6 0,000 0,01759535 0,06866685 ! plasminogen activation GO:0031639 9 6 0,000 0,01759535 0,06855734 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01759535 0,06844817 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01759535 0,06833935 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01759535 0,06823087 ! protein deubiquitination GO:0016579 16 6 0,000 0,01759535 0,06812274 ! protein destabilization GO:0031648 9 6 0,000 0,01759535 0,06801495 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01759535 0,0679075 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01759535 0,06780039 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01759535 0,06769362 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01759535 0,06758719 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01759535 0,06748108 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01759535 0,06737531 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01759535 0,06726987 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01759535 0,06716477 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01759535 0,06705998 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01759535 0,06695553 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01759535 0,0668514 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01759535 0,06674759 ! neural plate development GO:0001840 9 6 0,000 0,01759535 0,06664411 ! catecholamine transport GO:0051937 9 6 0,000 0,01759535 0,06654094 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01759535 0,0664381 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01759535 0,06633557 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01759535 0,06623336 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01759535 0,06613146 ! maternal placenta development GO:0001893 12 6 0,000 0,01759535 0,06602988 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01759535 0,0659286 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01759535 0,06582764 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01759535 0,06572699 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01759535 0,06562664 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01759535 0,0655266 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01759535 0,06542686 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01759535 0,06532743 GO:0055081|anion homeostasis, ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,01783096 0,06610172 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,01783096 0,06600156 ! activation of immune response GO:0002253 120 70 1,000 0,01832047 0,06771091 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,01832047 0,06760862 ! appendage morphogenesis GO:0035107 150 72 1,000 0,01931641 0,07117647 GO:0035108|limb morphogenesis, ! B cell activation GO:0042113 179 72 1,000 0,01931641 0,07106928 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,01931641 0,0709624 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,01931641 0,07085585 ! appendage development GO:0048736 151 73 1,000 0,01982277 0,07260425 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 1,000 0,01982277 0,07249556 ! acute inflammatory response GO:0002526 118 74 1,000 0,02033467 0,07425651 ! regulation of caspase activity GO:0043281 136 74 1,000 0,02033467 0,07414568 ! tRNA transcription GO:0009304 17 7 0,000 0,02049795 0,07462965 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02049795 0,07451859 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02049795 0,07440787 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02049795 0,07429747 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02049795 0,0741874 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02049795 0,07407765 ! sleep GO:0030431 16 7 0,000 0,02049795 0,07396823 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02049795 0,07385914 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02049795 0,07375036 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02049795 0,0736419 ! prostate gland development GO:0030850 14 7 0,000 0,02049795 0,07353377 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02049795 0,07342594 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02049795 0,07331844 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02049795 0,07321125 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02049795 0,07310437 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02049795 0,07299781 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02049795 0,07289155 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02049795 0,0727856 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02049795 0,07267996 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02049795 0,07257463 ! glycolipid transport GO:0046836 11 7 0,000 0,02049795 0,0724696 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02049795 0,07236488 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02049795 0,07226045 ! neuron adhesion GO:0007158 14 7 0,000 0,02049795 0,07215633 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02049795 0,07205251 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02049795 0,07194899 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02049795 0,07184576 ! mRNA stabilization GO:0048255 18 7 0,000 0,02049795 0,07174283 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02049795 0,07164019 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02049795 0,07153785 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02049795 0,0714358 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02049795 0,07133404 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02049795 0,07123257 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02049795 0,07113138 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02049795 0,07103049 ! lipoprotein transport GO:0042953 14 7 0,000 0,02049795 0,07092988 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02049795 0,07082955 ! rhythmic behavior GO:0007622 17 7 0,000 0,02049795 0,07072951 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02049795 0,07062975 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02049795 0,07053027 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02049795 0,07043107 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02049795 0,07033215 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02049795 0,07023351 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02049795 0,07013515 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02049795 0,07003705 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02049795 0,06993924 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02049795 0,06984169 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02049795 0,06974442 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02049795 0,06964742 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02049795 0,06955069 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02049795 0,06945422 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02049795 0,06935803 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02049795 0,06926209 ! spinal cord patterning GO:0021511 14 7 0,000 0,02049795 0,06916643 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02049795 0,06907103 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02049795 0,06897589 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02049795 0,06888101 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02049795 0,06878639 ! adrenal gland development GO:0030325 17 7 0,000 0,02049795 0,06869204 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02049795 0,06859794 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02049795 0,0685041 ! ovulation GO:0030728 10 7 0,000 0,02049795 0,06841051 ! adenohypophysis development GO:0021984 11 7 0,000 0,02049795 0,06831718 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02049795 0,06822411 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02049795 0,06813128 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02049795 0,06803872 ! microtubule nucleation GO:0007020 21 7 0,000 0,02049795 0,0679464 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02049795 0,06785433 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02049795 0,06776251 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02049795 0,06767094 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02049795 0,06757961 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02049795 0,06748854 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02049795 0,0673977 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02049795 0,06730712 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02049795 0,06721677 ! galactose metabolic process GO:0006012 13 7 0,000 0,02049795 0,06712667 ! vesicle fusion GO:0006906 20 7 0,000 0,02049795 0,06703681 ! response to dietary excess GO:0002021 8 7 0,000 0,02049795 0,06694718 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02049795 0,0668578 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02049795 0,06676866 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02049795 0,06667975 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02049795 0,06659108 ! organ growth GO:0035265 15 7 0,000 0,02049795 0,06650265 ! nucleoside transport GO:0015858 11 7 0,000 0,02049795 0,06641445 ! nucleoside salvage GO:0043174 11 7 0,000 0,02049795 0,06632648 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02049795 0,06623875 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02049795 0,06615125 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02049795 0,06606398 ! parturition GO:0007567 16 7 0,000 0,02049795 0,06597694 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02049795 0,06589012 ! rRNA modification GO:0000154 14 7 0,000 0,02049795 0,06580354 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02049795 0,06571718 ! spindle checkpoint GO:0031577 16 7 0,000 0,02049795 0,06563105 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02049795 0,06554515 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02049795 0,06545947 ! monocyte differentiation GO:0030224 16 7 0,000 0,02049795 0,06537401 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02049795 0,06528878 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02049795 0,06520377 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02049795 0,06511898 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02049795 0,06503441 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02049795 0,06495006 ! fibrinolysis GO:0042730 11 7 0,000 0,02049795 0,06486593 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02049795 0,06478201 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02049795 0,06469831 ! eating behavior GO:0042755 8 7 0,000 0,02049795 0,06461483 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02049795 0,06453156 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02049795 0,06444851 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02049795 0,06436567 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02049795 0,06428305 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02049795 0,06420063 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02049795 0,06411843 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02049795 0,06403644 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02049795 0,06395465 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02049795 0,06387308 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02049795 0,06379171 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02049795 0,06371055 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02049795 0,0636296 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02049795 0,06354885 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02049795 0,06346831 ! histone ubiquitination GO:0016574 9 7 0,000 0,02049795 0,06338797 ! regulation of meiosis GO:0040020 12 7 0,000 0,02049795 0,06330783 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02049795 0,0632279 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02049795 0,06314816 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02049795 0,06306863 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02049795 0,0629893 ! transcription termination GO:0006353 14 7 0,000 0,02049795 0,06291017 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02049795 0,06283123 ! anaphase GO:0051322 18 7 0,000 0,02049795 0,0627525 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02049795 0,06267396 ! axonal fasciculation GO:0007413 19 7 0,000 0,02049795 0,06259562 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02049795 0,06251747 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02049795 0,06243952 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02049795 0,06236176 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02049795 0,0622842 ! diuresis GO:0030146 12 7 0,000 0,02049795 0,06220683 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02049795 0,06212965 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02049795 0,06205266 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02049795 0,06197586 ! antibiotic transport GO:0042891 9 7 0,000 0,02049795 0,06189925 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02049795 0,06182283 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02049795 0,0617466 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02049795 0,06167056 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02049795 0,0615947 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02049795 0,06151903 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02049795 0,06144355 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02049795 0,06136825 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02049795 0,06129314 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02049795 0,06121821 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02049795 0,06114346 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02049795 0,0610689 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02049795 0,06099451 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02049795 0,06092031 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02049795 0,06084629 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02049795 0,06077244 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02049795 0,06069878 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02049795 0,0606253 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02049795 0,06055199 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02049795 0,06047886 ! muscle adaptation GO:0043500 13 7 0,000 0,02049795 0,0604059 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02049795 0,06033313 ! retina homeostasis GO:0001895 12 7 0,000 0,02049795 0,06026052 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02049795 0,06018809 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02049795 0,06011584 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02049795 0,06004376 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02049795 0,05997185 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,02085208 0,06093496 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,02085208 0,06086216 ! eye development GO:0001654 155 75 1,000 0,02085208 0,06078953 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,02137495 0,06223958 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,02190326 0,06370198 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,02190326 0,06362623 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,02190326 0,06355067 ! regulation of catabolic process GO:0009894 173 77 1,000 0,02190326 0,06347528 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,02243696 0,06494491 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,02297603 0,06642656 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,02297603 0,06634804 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02339205 0,06746964 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02339205 0,06739008 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02339205 0,0673107 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02339205 0,06723151 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02339205 0,06715251 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02339205 0,06707369 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02339205 0,06699506 ! male meiosis GO:0007140 9 8 0,000 0,02339205 0,06691661 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02339205 0,06683835 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02339205 0,06676026 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02339205 0,06668236 ! meiotic prophase I GO:0007128 14 8 0,000 0,02339205 0,06660465 ! response to zinc ion GO:0010043 12 8 0,000 0,02339205 0,06652711 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02339205 0,06644975 ! oligopeptide transport GO:0006857 16 8 0,000 0,02339205 0,06637257 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02339205 0,06629558 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02339205 0,06621876 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02339205 0,06614211 ! signal peptide processing GO:0006465 12 8 0,000 0,02339205 0,06606565 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02339205 0,06598936 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02339205 0,06591325 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02339205 0,06583731 ! succinate metabolic process GO:0006105 17 8 0,000 0,02339205 0,06576155 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02339205 0,06568596 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02339205 0,06561055 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02339205 0,06553531 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02339205 0,06546024 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02339205 0,06538534 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02339205 0,06531061 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02339205 0,06523606 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02339205 0,06516167 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02339205 0,06508746 ! reflex GO:0060004 17 8 0,000 0,02339205 0,06501341 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02339205 0,06493953 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02339205 0,06486582 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02339205 0,06479227 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02339205 0,0647189 ! pigment granule organization GO:0048753 17 8 0,000 0,02339205 0,06464569 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02339205 0,06457264 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02339205 0,06449976 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02339205 0,06442704 ! histidine catabolic process GO:0006548 10 8 0,000 0,02339205 0,06435449 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02339205 0,0642821 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02339205 0,06420987 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02339205 0,06413781 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02339205 0,0640659 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02339205 0,06399416 ! melanin metabolic process GO:0006582 17 8 0,000 0,02339205 0,06392258 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02339205 0,06385116 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02339205 0,0637799 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02339205 0,06370879 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02339205 0,06363785 ! macrophage activation GO:0042116 13 8 0,000 0,02339205 0,06356706 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02339205 0,06349643 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02339205 0,06342596 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02339205 0,06335564 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02339205 0,06328548 ! purine salvage GO:0043101 12 8 0,000 0,02339205 0,06321547 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02339205 0,06314562 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02339205 0,06307592 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02339205 0,06300638 ! osteoblast development GO:0002076 17 8 0,000 0,02339205 0,06293699 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02339205 0,06286775 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02339205 0,06279867 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02339205 0,06272973 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02339205 0,06266095 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02339205 0,06259232 ! response to UV-B GO:0010224 17 8 0,000 0,02339205 0,06252384 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02339205 0,0624555 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02339205 0,06238732 ! intermediate filament organization GO:0045109 12 8 0,000 0,02339205 0,06231929 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02339205 0,0622514 ! cellular extravasation GO:0045123 13 8 0,000 0,02339205 0,06218366 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02339205 0,06211607 ! response to antibiotic GO:0046677 11 8 0,000 0,02339205 0,06204863 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02339205 0,06198133 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02339205 0,06191418 ! DNA topological change GO:0006265 12 8 0,000 0,02339205 0,06184717 ! response to tropane GO:0014073 15 8 0,000 0,02339205 0,06178031 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02339205 0,06171359 ! melanosome transport GO:0032402 13 8 0,000 0,02339205 0,06164702 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02339205 0,06158059 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02339205 0,0615143 ! mast cell activation GO:0045576 14 8 0,000 0,02339205 0,06144816 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02339205 0,06138215 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02339205 0,06131629 ! gas homeostasis GO:0033483 14 8 0,000 0,02339205 0,06125057 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02339205 0,061185 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02339205 0,06111956 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02339205 0,06105426 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02339205 0,0609891 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02339205 0,06092408 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02339205 0,0608592 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02339205 0,06079445 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02339205 0,06072985 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02339205 0,06066538 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02339205 0,06060105 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02339205 0,06053685 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02339205 0,06047279 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02339205 0,06040887 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02339205 0,06034508 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02339205 0,06028142 ! hormone catabolic process GO:0042447 17 8 0,000 0,02339205 0,0602179 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02339205 0,06015451 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02339205 0,06009126 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02339205 0,06002814 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02339205 0,05996515 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02339205 0,05990229 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02339205 0,05983957 ! adult feeding behavior GO:0008343 10 8 0,000 0,02339205 0,05977697 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02339205 0,05971451 ! ATP catabolic process GO:0006200 11 8 0,000 0,02339205 0,05965218 ! blastocyst growth GO:0001832 19 8 0,000 0,02339205 0,05958998 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02339205 0,0595279 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02339205 0,05946596 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02339205 0,05940414 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02339205 0,05934246 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02339205 0,0592809 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02339205 0,05921947 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02339205 0,05915816 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02339205 0,05909699 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02339205 0,05903594 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02339205 0,05897501 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02339205 0,05891421 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02339205 0,05885354 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02339205 0,05879299 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02339205 0,05873257 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02339205 0,05867227 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02339205 0,05861209 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02339205 0,05855204 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02339205 0,0584921 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02339205 0,0584323 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02339205 0,05837261 ! response to hypoxia GO:0001666 178 81 1,000 0,0240701 0,06000333 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,0240701 0,05994216 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,02462504 0,06126168 ! protein import into nucleus GO:0006606 174 82 1,000 0,02462504 0,06119936 ! response to oxygen levels GO:0070482 183 83 1,000 0,02518519 0,06252787 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,02518519 0,06246439 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,02518519 0,06240104 ! T cell activation GO:0042110 189 84 1,000 0,02575053 0,06373713 ! regulation of ligase activity GO:0051340 147 84 1,000 0,02575053 0,06367262 ! axon extension GO:0048675 16 9 0,000 0,02627769 0,0649104 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02627769 0,06484483 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02627769 0,0647794 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02627769 0,0647141 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02627769 0,06464893 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02627769 0,06458389 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02627769 0,06451898 ! reproductive behavior GO:0019098 22 9 0,000 0,02627769 0,0644542 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02627769 0,06438956 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02627769 0,06432504 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02627769 0,06426065 ! UTP metabolic process GO:0046051 10 9 0,000 0,02627769 0,06419639 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02627769 0,06413225 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02627769 0,06406825 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02627769 0,06400437 ! artery development GO:0060840 25 9 0,000 0,02627769 0,06394062 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02627769 0,063877 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02627769 0,06381351 ! equilibrioception GO:0050957 20 9 0,000 0,02627769 0,06375014 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02627769 0,06368689 ! chemosensory behavior GO:0007635 21 9 0,000 0,02627769 0,06362377 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02627769 0,06356078 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02627769 0,06349791 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02627769 0,06343516 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02627769 0,06337254 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02627769 0,06331005 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02627769 0,06324767 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02627769 0,06318542 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02627769 0,06312329 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02627769 0,06306128 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02627769 0,0629994 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02627769 0,06293763 ! protein targeting to ER GO:0045047 25 9 0,000 0,02627769 0,06287599 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02627769 0,06281447 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02627769 0,06275307 ! T cell selection GO:0045058 27 9 0,000 0,02627769 0,06269178 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02627769 0,06263062 ! glycine catabolic process GO:0006546 15 9 0,000 0,02627769 0,06256958 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02627769 0,06250865 ! endosome organization GO:0007032 20 9 0,000 0,02627769 0,06244785 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02627769 0,06238716 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02627769 0,06232659 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02627769 0,06226614 ! mannose metabolic process GO:0006013 13 9 0,000 0,02627769 0,0622058 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02627769 0,06214558 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02627769 0,06208548 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02627769 0,06202549 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02627769 0,06196562 ! receptor clustering GO:0043113 20 9 0,000 0,02627769 0,06190587 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02627769 0,06184623 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02627769 0,0617867 ! retinol metabolic process GO:0042572 20 9 0,000 0,02627769 0,06172729 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02627769 0,061668 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02627769 0,06160882 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02627769 0,06154975 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02627769 0,06149079 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02627769 0,06143195 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02627769 0,06137322 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02627769 0,0613146 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02627769 0,06125609 ! response to amine stimulus GO:0014075 13 9 0,000 0,02627769 0,0611977 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02627769 0,06113942 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02627769 0,06108124 ! erythrocyte development GO:0048821 17 9 0,000 0,02627769 0,06102318 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02627769 0,06096523 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02627769 0,06090739 ! renal water homeostasis GO:0003091 15 9 0,000 0,02627769 0,06084966 ! postreplication repair GO:0006301 25 9 0,000 0,02627769 0,06079203 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02627769 0,06073452 ! icosanoid secretion GO:0032309 15 9 0,000 0,02627769 0,06067711 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02627769 0,06061982 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02627769 0,06056263 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02627769 0,06050555 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02627769 0,06044857 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02627769 0,06039171 ! sterol catabolic process GO:0016127 14 9 0,000 0,02627769 0,06033495 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02627769 0,0602783 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02627769 0,06022175 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02627769 0,06016531 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02627769 0,06010898 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02627769 0,06005275 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02627769 0,05999662 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02627769 0,0599406 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02627769 0,05988469 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02627769 0,05982888 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02627769 0,05977317 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02627769 0,05971757 ! purine base metabolic process GO:0006144 25 9 0,000 0,02627769 0,05966207 ! pigment granule transport GO:0051904 17 9 0,000 0,02627769 0,05960667 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02627769 0,05955138 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02627769 0,05949619 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02627769 0,0594411 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02627769 0,05938611 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02627769 0,05933123 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02627769 0,05927644 ! mitochondrion localization GO:0051646 18 9 0,000 0,02627769 0,05922176 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,02689662 0,06056079 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 159 87 1,000 0,02747731 0,06181129 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,02806304 0,06307083 ! regulation of DNA binding GO:0051101 167 89 1,000 0,02865378 0,06433932 ! tube morphogenesis GO:0035239 194 89 1,000 0,02865378 0,06428024 ! protein localization in nucleus GO:0034504 192 89 1,000 0,02865378 0,06422126 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02915487 0,06528447 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02915487 0,06522468 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02915487 0,06516501 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02915487 0,06510544 ! associative learning GO:0008306 21 10 0,000 0,02915487 0,06504599 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02915487 0,06498664 ! phosphate transport GO:0006817 24 10 0,000 0,02915487 0,0649274 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02915487 0,06486826 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02915487 0,06480924 ! CTP metabolic process GO:0046036 11 10 0,000 0,02915487 0,06475032 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02915487 0,06469151 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02915487 0,06463281 ! GTP metabolic process GO:0046039 11 10 0,000 0,02915487 0,06457421 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02915487 0,06451572 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02915487 0,06445733 ! social behavior GO:0035176 29 10 0,000 0,02915487 0,06439905 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02915487 0,06434088 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02915487 0,06428281 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02915487 0,06422485 ! androgen metabolic process GO:0008209 17 10 0,000 0,02915487 0,06416699 ! phospholipid efflux GO:0033700 19 10 0,000 0,02915487 0,06410923 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02915487 0,06405158 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02915487 0,06399403 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02915487 0,06393658 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02915487 0,06387924 ! lung alveolus development GO:0048286 26 10 0,000 0,02915487 0,063822 ! pathogenesis GO:0009405 17 10 0,000 0,02915487 0,06376487 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02915487 0,06370783 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02915487 0,0636509 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02915487 0,06359407 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02915487 0,06353734 ! endoderm development GO:0007492 18 10 0,000 0,02915487 0,06348071 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02915487 0,06342418 ! arginine catabolic process GO:0006527 17 10 0,000 0,02915487 0,06336775 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02915487 0,06331143 ! proline metabolic process GO:0006560 13 10 0,000 0,02915487 0,0632552 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02915487 0,06319907 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02915487 0,06314304 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02915487 0,06308712 ! V(D)J recombination GO:0033151 34 10 0,000 0,02915487 0,06303129 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02915487 0,06297556 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02915487 0,06291992 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02915487 0,06286439 ! B cell proliferation GO:0042100 19 10 0,000 0,02915487 0,06280895 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02915487 0,06275362 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02915487 0,06269838 ! multicellular organism growth GO:0035264 19 10 0,000 0,02915487 0,06264323 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02915487 0,06258818 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02915487 0,06253323 ! ruffle organization GO:0031529 17 10 0,000 0,02915487 0,06247838 ! epithelial cell development GO:0002064 21 10 0,000 0,02915487 0,06242362 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02915487 0,06236896 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02915487 0,0623144 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02915487 0,06225993 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02915487 0,06220555 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02915487 0,06215127 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02915487 0,06209708 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,02915487 0,06204299 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02915487 0,06198899 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02915487 0,06193509 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02915487 0,06188128 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02915487 0,06182756 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02915487 0,06177394 ! segment specification GO:0007379 15 10 0,000 0,02915487 0,06172041 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02915487 0,06166697 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02915487 0,06161363 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02915487 0,06156038 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02915487 0,06150721 ! response to dsRNA GO:0043331 23 10 0,000 0,02915487 0,06145415 ! DNA ligation GO:0006266 18 10 0,000 0,02915487 0,06140117 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02915487 0,06134828 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02915487 0,06129549 ! melanosome localization GO:0032400 16 10 0,000 0,02915487 0,06124278 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02915487 0,06119017 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02915487 0,06113764 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02915487 0,06108521 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02915487 0,06103287 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02915487 0,06098061 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02915487 0,06092845 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02915487 0,06087637 ! protein sumoylation GO:0016925 17 10 0,000 0,02915487 0,06082438 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02915487 0,06077249 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02915487 0,06072068 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02915487 0,06066896 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02915487 0,06061732 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02915487 0,06056578 ! salivary gland development GO:0007431 28 10 0,000 0,02915487 0,06051432 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02915487 0,06046295 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02915487 0,06041167 ! midbrain development GO:0030901 14 10 0,000 0,02915487 0,06036047 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02915487 0,06030936 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02915487 0,06025834 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02915487 0,0602074 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02915487 0,06015655 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02915487 0,06010578 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02915487 0,0600551 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02915487 0,06000451 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02915487 0,059954 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02915487 0,05990358 ! detection of calcium ion GO:0005513 24 10 0,000 0,02915487 0,05985324 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02915487 0,05980298 ! blastocyst formation GO:0001825 18 10 0,000 0,02915487 0,05975281 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02915487 0,05970273 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02915487 0,05965273 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02915487 0,05960281 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02915487 0,05955297 ! response to nicotine GO:0035094 20 10 0,000 0,02915487 0,05950322 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02915487 0,05945355 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02915487 0,05940397 ! ossification GO:0001503 205 91 1,000 0,02985016 0,06076994 ! gland development GO:0048732 220 91 1,000 0,02985016 0,06071934 ! bone development GO:0060348 206 92 1,000 0,03045573 0,06189962 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,03106617 0,06308783 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,03106617 0,06303543 GO:0010498|proteasomal protein catabolic process, ! negative regulation of muscle development GO:0048635 27 11 0,000 0,03202364 0,06492427 ! respiratory burst GO:0045730 17 11 0,000 0,03202364 0,06487044 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,03202364 0,06481669 ! neuron fate specification GO:0048665 18 11 0,000 0,03202364 0,06476304 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03202364 0,06470947 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,03202364 0,06465599 ! thyroid gland development GO:0030878 26 11 0,000 0,03202364 0,0646026 ! synapsis GO:0007129 14 11 0,000 0,03202364 0,0645493 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03202364 0,06449608 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,03202364 0,06444296 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,03202364 0,06438992 ! response to pain GO:0048265 27 11 0,000 0,03202364 0,06433697 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03202364 0,0642841 ! blood vessel remodeling GO:0001974 30 11 0,000 0,03202364 0,06423132 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,03202364 0,06417863 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,03202364 0,06412602 ! bone resorption GO:0045453 16 11 0,000 0,03202364 0,06407351 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03202364 0,06402107 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03202364 0,06396872 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03202364 0,06391646 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03202364 0,06386429 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03202364 0,06381219 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03202364 0,06376019 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,03202364 0,06370827 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,03202364 0,06365643 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03202364 0,06360467 ! UV protection GO:0009650 20 11 0,000 0,03202364 0,06355301 ! adult heart development GO:0007512 16 11 0,000 0,03202364 0,06350142 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,03202364 0,06344992 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03202364 0,0633985 ! macroautophagy GO:0016236 19 11 0,000 0,03202364 0,06334717 ! temperature homeostasis GO:0001659 18 11 0,000 0,03202364 0,06329591 ! behavioral fear response GO:0001662 27 11 0,000 0,03202364 0,06324475 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03202364 0,06319366 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03202364 0,06314266 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,03202364 0,06309173 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,03202364 0,06304089 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03202364 0,06299014 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,03202364 0,06293946 ! regulation of organ growth GO:0046620 14 11 0,000 0,03202364 0,06288887 ! pigment granule localization GO:0051875 20 11 0,000 0,03202364 0,06283835 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03202364 0,06278792 ! vasoconstriction GO:0042310 20 11 0,000 0,03202364 0,06273757 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,03202364 0,0626873 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03202364 0,06263711 ! embryonic axis specification GO:0000578 19 11 0,000 0,03202364 0,062587 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03202364 0,06253697 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03202364 0,06248702 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03202364 0,06243715 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03202364 0,06238736 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03202364 0,06233765 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03202364 0,06228802 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,03202364 0,06223846 ! prophase GO:0051324 17 11 0,000 0,03202364 0,06218899 ! neuroblast proliferation GO:0007405 25 11 0,000 0,03202364 0,0621396 ! nucleosome positioning GO:0016584 15 11 0,000 0,03202364 0,06209028 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03202364 0,06204104 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03202364 0,06199188 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03202364 0,0619428 ! apical protein localization GO:0045176 18 11 0,000 0,03202364 0,06189379 ! acid secretion GO:0046717 20 11 0,000 0,03202364 0,06184486 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03202364 0,06179601 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03202364 0,06174724 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,03202364 0,06169854 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03202364 0,06164992 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03202364 0,06160138 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,03202364 0,06155291 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,03202364 0,06150452 ! cholesterol efflux GO:0033344 21 11 0,000 0,03202364 0,06145621 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03202364 0,06140797 ! oocyte development GO:0048599 20 11 0,000 0,03202364 0,0613598 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,03202364 0,06131172 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,03202364 0,0612637 ! embryonic gut development GO:0048566 19 11 0,000 0,03202364 0,06121577 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03202364 0,0611679 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,03202364 0,06112012 ! activation of innate immune response GO:0002218 16 11 0,000 0,03202364 0,0610724 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03202364 0,06102477 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,03202364 0,0609772 ! lysogeny GO:0030069 22 11 0,000 0,03202364 0,06092971 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03202364 0,0608823 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,03202364 0,06083495 ! sequestering of metal ion GO:0051238 15 11 0,000 0,03202364 0,06078768 ! regulation of defense response GO:0031347 171 95 1,000 0,03230156 0,06126763 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,03230156 0,0612201 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,03488401 0,06606328 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,03488401 0,06601211 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,03488401 0,06596102 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,03488401 0,06591 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03488401 0,06585907 ! protein complex disassembly GO:0043241 28 12 0,000 0,03488401 0,06580821 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03488401 0,06575743 ! hippocampus development GO:0021766 29 12 0,000 0,03488401 0,06570673 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,03488401 0,06565611 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,03488401 0,06560557 ! T cell proliferation GO:0042098 32 12 0,000 0,03488401 0,0655551 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03488401 0,06550471 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,03488401 0,0654544 ! ventral spinal cord development GO:0021517 25 12 0,000 0,03488401 0,06540417 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,03488401 0,06535401 ! drug transport GO:0015893 16 12 0,000 0,03488401 0,06530393 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,03488401 0,06525393 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,03488401 0,065204 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,03488401 0,06515415 ! polyamine metabolic process GO:0006595 18 12 0,000 0,03488401 0,06510438 ! focal adhesion formation GO:0048041 37 12 0,000 0,03488401 0,06505468 ! mitotic spindle organization GO:0007052 23 12 0,000 0,03488401 0,06500506 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,03488401 0,06495551 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,03488401 0,06490604 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,03488401 0,06485665 ! lipid digestion GO:0044241 21 12 0,000 0,03488401 0,06480733 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,03488401 0,06475808 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03488401 0,06470891 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,03488401 0,06465981 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,03488401 0,06461079 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03488401 0,06456184 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,03488401 0,06451297 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,03488401 0,06446417 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,03488401 0,06441544 ! snRNA metabolic process GO:0016073 30 12 0,000 0,03488401 0,06436679 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,03488401 0,06431821 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,03488401 0,06426971 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03488401 0,06422128 ! cranial nerve development GO:0021545 23 12 0,000 0,03488401 0,06417292 ! fucose catabolic process GO:0019317 25 12 0,000 0,03488401 0,06412463 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,03488401 0,06407642 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,03488401 0,06402827 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03488401 0,06398021 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,03488401 0,06393221 ! zymogen activation GO:0031638 18 12 0,000 0,03488401 0,06388428 ! T cell homeostasis GO:0043029 28 12 0,000 0,03488401 0,06383643 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,03488401 0,06378865 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,03488401 0,06374094 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,03488401 0,0636933 ! oocyte differentiation GO:0009994 21 12 0,000 0,03488401 0,06364573 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,03488401 0,06359823 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,03488401 0,06355081 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,03488401 0,06350345 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,03488401 0,06345617 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,03488401 0,06340895 ! defense response to fungus GO:0050832 15 12 0,000 0,03488401 0,06336181 ! embryonic placenta development GO:0001892 21 12 0,000 0,03488401 0,06331474 ! lamellipodium assembly GO:0030032 24 12 0,000 0,03488401 0,06326773 ! response to cold GO:0009409 17 12 0,000 0,03488401 0,0632208 ! establishment of cell polarity GO:0030010 21 12 0,000 0,03488401 0,06317393 ! regulation of synapse organization GO:0050807 18 12 0,000 0,03488401 0,06312714 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,03547303 0,06414553 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 1,000 0,03547303 0,06409809 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03773601 0,06813678 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03773601 0,06808646 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03773601 0,06803621 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03773601 0,06798604 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03773601 0,06793593 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03773601 0,06788591 ! peroxisomal transport GO:0043574 28 13 0,000 0,03773601 0,06783596 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03773601 0,06778608 ! cartilage condensation GO:0001502 22 13 0,000 0,03773601 0,06773627 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,03773601 0,06768654 ! organelle fusion GO:0048284 36 13 0,000 0,03773601 0,06763688 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03773601 0,06758729 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,03773601 0,06753778 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,03773601 0,06748833 ! endocrine pancreas development GO:0031018 25 13 0,000 0,03773601 0,06743896 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,03773601 0,06738967 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03773601 0,06734044 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03773601 0,06729129 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03773601 0,06724221 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03773601 0,0671932 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03773601 0,06714426 ! methionine metabolic process GO:0006555 31 13 0,000 0,03773601 0,06709539 ! plasma membrane organization GO:0007009 27 13 0,000 0,03773601 0,06704659 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03773601 0,06699787 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03773601 0,06694921 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03773601 0,06690063 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,03773601 0,06685211 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,03773601 0,06680367 ! exocrine system development GO:0035272 34 13 0,000 0,03773601 0,0667553 ! asymmetric protein localization GO:0008105 24 13 0,000 0,03773601 0,06670699 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,03773601 0,06665876 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,03773601 0,0666106 ! L-glutamate transport GO:0015813 30 13 0,000 0,03773601 0,0665625 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03773601 0,06651448 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03773601 0,06646652 ! protein homotetramerization GO:0051289 24 13 0,000 0,03773601 0,06641863 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03773601 0,06637082 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03773601 0,06632307 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,03773601 0,06627539 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,03773601 0,06622778 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03773601 0,06618023 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03773601 0,06613276 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03773601 0,06608535 ! histone methylation GO:0016571 29 13 0,000 0,03773601 0,06603801 ! chromatin silencing GO:0006342 29 13 0,000 0,03773601 0,06599074 ! gland morphogenesis GO:0022612 31 13 0,000 0,03773601 0,06594354 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,03773601 0,0658964 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,03773601 0,06584933 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03773601 0,06580233 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,03773601 0,06575539 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,03773601 0,06570853 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,03773601 0,06566173 ! spleen development GO:0048536 24 13 0,000 0,03773601 0,06561499 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,03773601 0,06556832 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03773601 0,06552172 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,03773601 0,06547519 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03773601 0,06542872 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,03773601 0,06538231 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03773601 0,06533598 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03773601 0,06528971 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03773601 0,0652435 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03773601 0,06519736 ! insulin secretion GO:0030073 24 13 0,000 0,03773601 0,06515128 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03773601 0,06510527 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,03773601 0,06505933 ! acrosome reaction GO:0007340 19 13 0,000 0,03773601 0,06501344 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03773601 0,06496763 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03773601 0,06492188 ! rRNA transcription GO:0009303 28 14 0,000 0,04057966 0,06976502 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,04057966 0,06971596 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,04057966 0,06966697 ! water transport GO:0006833 21 14 0,000 0,04057966 0,06961805 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,04057966 0,06956919 ! non-recombinational repair GO:0000726 29 14 0,000 0,04057966 0,06952041 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,04057966 0,06947169 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,04057966 0,06942304 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,04057966 0,06937446 ! RNA polyadenylation GO:0043631 32 14 0,000 0,04057966 0,06932594 ! lipid localization GO:0010876 32 14 0,000 0,04057966 0,0692775 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,04057966 0,06922912 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,04057966 0,06918081 ! regulated secretory pathway GO:0045055 24 14 0,000 0,04057966 0,06913257 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,04057966 0,06908439 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,04057966 0,06903628 ! arginine metabolic process GO:0006525 21 14 0,000 0,04057966 0,06898824 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,04057966 0,06894026 ! regulation of heart rate GO:0002027 25 14 0,000 0,04057966 0,06889236 ! fear response GO:0042596 34 14 0,000 0,04057966 0,06884451 ! organic alcohol transport GO:0015850 29 14 0,000 0,04057966 0,06879674 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,04057966 0,06874903 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,04057966 0,06870139 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04057966 0,06865381 ! neutral amino acid transport GO:0015804 28 14 0,000 0,04057966 0,0686063 ! bone mineralization GO:0030282 18 14 0,000 0,04057966 0,06855885 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,04057966 0,06851147 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,04057966 0,06846416 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,04057966 0,06841691 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,04057966 0,06836972 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,04057966 0,06832261 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,04057966 0,06827555 ! ribosome assembly GO:0042255 18 14 0,000 0,04057966 0,06822856 ! cerebellum development GO:0021549 23 14 0,000 0,04057966 0,06818164 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,04057966 0,06813478 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,04057966 0,06808798 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,04057966 0,06804125 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,04057966 0,06799458 ! NADP metabolic process GO:0006739 24 14 0,000 0,04057966 0,06794798 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,04057966 0,06790144 ! oxygen transport GO:0015671 22 14 0,000 0,04057966 0,06785496 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04057966 0,06780855 ! male genitalia development GO:0030539 26 14 0,000 0,04057966 0,0677622 ! regulation of RNA stability GO:0043487 33 14 0,000 0,04057966 0,06771592 ! regulation of axon extension GO:0030516 43 14 0,000 0,04057966 0,06766969 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,04057966 0,06762353 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,04057966 0,06757744 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04341498 0,07224986 ! lactation GO:0007595 30 15 0,000 0,04341498 0,07220068 ! reproductive cellular process GO:0048610 22 15 0,000 0,04341498 0,07215157 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04341498 0,07210252 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,04341498 0,07205353 ! superoxide anion generation GO:0042554 22 15 0,000 0,04341498 0,07200462 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,04341498 0,07195577 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,04341498 0,07190698 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,04341498 0,07185827 ! copper ion transport GO:0006825 22 15 0,000 0,04341498 0,07180962 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,04341498 0,07176103 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,04341498 0,07171251 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,04341498 0,07166406 ! sulfate transport GO:0008272 27 15 0,000 0,04341498 0,07161567 ! response to cAMP GO:0051591 25 15 0,000 0,04341498 0,07156734 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,04341498 0,07151908 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,04341498 0,07147089 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,04341498 0,07142276 ! response to hexose stimulus GO:0009746 25 15 0,000 0,04341498 0,0713747 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,04341498 0,0713267 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,04341498 0,07127876 ! vesicle coating GO:0006901 38 15 0,000 0,04341498 0,07123089 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,04341498 0,07118309 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,04341498 0,07113535 ! regulation of exocytosis GO:0017157 26 15 0,000 0,04341498 0,07108767 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,04341498 0,07104005 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,04341498 0,0709925 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,04341498 0,07094502 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,04341498 0,07089759 ! regulation of vasodilation GO:0042312 27 15 0,000 0,04341498 0,07085023 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,04341498 0,07080294 ! histone deacetylation GO:0016575 24 15 0,000 0,04341498 0,0707557 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04341498 0,07070853 ! water homeostasis GO:0030104 28 15 0,000 0,04341498 0,07066143 ! cofactor transport GO:0051181 30 15 0,000 0,04341498 0,07061438 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04341498 0,0705674 ! muscle maintenance GO:0046716 26 15 0,000 0,04341498 0,07052048 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,04341498 0,07047362 ! intestinal absorption GO:0050892 31 15 0,000 0,04341498 0,07042683 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04341498 0,07038009 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,04341498 0,07033342 ! heme biosynthetic process GO:0006783 33 15 0,000 0,04341498 0,07028681 ! cell killing GO:0001906 32 15 0,000 0,04341498 0,07024027 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,04341498 0,07019378 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,04341498 0,07014736 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,04341498 0,07010099 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,04341498 0,07005469 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,04341498 0,07000845 ! actin filament polymerization GO:0030041 27 15 0,000 0,04341498 0,06996227 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,04341498 0,06991615 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,04624201 0,07441978 ! positive regulation of cell size GO:0045793 29 16 0,000 0,04624201 0,07437079 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,04624201 0,07432186 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,04624201 0,074273 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,04624201 0,0742242 ! bone remodeling GO:0046849 28 16 0,000 0,04624201 0,07417546 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,04624201 0,07412679 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,04624201 0,07407818 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04624201 0,07402964 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,04624201 0,07398116 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,04624201 0,07393274 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,04624201 0,07388439 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,04624201 0,0738361 ! startle response GO:0001964 28 16 0,000 0,04624201 0,07378787 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,04624201 0,0737397 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,04624201 0,0736916 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,04624201 0,07364356 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,04624201 0,07359559 ! protein polyubiquitination GO:0000209 41 16 0,000 0,04624201 0,07354767 ! glutamate metabolic process GO:0006536 25 16 0,000 0,04624201 0,07349982 ! pituitary gland development GO:0021983 30 16 0,000 0,04624201 0,07345203 ! response to osmotic stress GO:0006970 27 16 0,000 0,04624201 0,07340431 ! lysosomal transport GO:0007041 31 16 0,000 0,04624201 0,07335664 ! fructose metabolic process GO:0006000 25 16 0,000 0,04624201 0,07330904 ! L-amino acid transport GO:0015807 33 16 0,000 0,04624201 0,0732615 ! stem cell development GO:0048864 46 16 0,000 0,04624201 0,07321402 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04624201 0,0731666 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04624201 0,07311924 ! intermediate filament-based process GO:0045103 36 16 0,000 0,04624201 0,07307195 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,04624201 0,07302471 ! negative regulation of immune response GO:0050777 38 16 0,000 0,04624201 0,07297754 ! axon cargo transport GO:0008088 46 16 0,000 0,04624201 0,07293042 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,04624201 0,07288337 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,04624201 0,07283638 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,04624201 0,07278945 ! DNA replication initiation GO:0006270 28 16 0,000 0,04624201 0,07274258 ! neuron recognition GO:0008038 40 16 0,000 0,04624201 0,07269577 ! mRNA splice site selection GO:0006376 44 16 0,000 0,04624201 0,07264902 ! tissue regeneration GO:0042246 27 16 0,000 0,04624201 0,07260233 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,04624201 0,0725557 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,04624201 0,07250913 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,04624201 0,07246262 ! biomineral formation GO:0031214 22 16 0,000 0,04624201 0,07241617 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,04624201 0,07236978 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,04624201 0,07232345 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,04624201 0,07227718 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04624201 0,07223096 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,04624201 0,07218481 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,04624201 0,07213871 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,04624201 0,07209268 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,04624201 0,0720467 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,04624201 0,07200078 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,04906076 0,07634104 ! metencephalon development GO:0022037 32 17 0,000 0,04906076 0,07629245 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,04906076 0,07624392 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,04906076 0,07619545 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,04906076 0,07614704 ! signal complex assembly GO:0007172 47 17 0,000 0,04906076 0,07609869 ! endothelial cell migration GO:0043542 31 17 0,000 0,04906076 0,0760504 ! gene silencing by RNA GO:0031047 38 17 0,000 0,04906076 0,07600218 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,04906076 0,07595402 ! glial cell development GO:0021782 28 17 0,000 0,04906076 0,07590591 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,04906076 0,07585787 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,04906076 0,07580989 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,04906076 0,07576197 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,04906076 0,07571411 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,04906076 0,07566631 ! myoblast differentiation GO:0045445 50 17 0,000 0,04906076 0,07561857 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,04906076 0,07557089 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,04906076 0,07552327 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,04906076 0,07547572 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,04906076 0,07542822 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,04906076 0,07538078 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,04906076 0,0753334 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,04906076 0,07528608 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,04906076 0,07523882 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,04906076 0,07519162 ! membrane budding GO:0006900 42 17 0,000 0,04906076 0,07514447 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,04906076 0,07509739 ! regulation of protein binding GO:0043393 33 17 0,000 0,04906076 0,07505037 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,04906076 0,0750034 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,04906076 0,0749565 ! genitalia development GO:0048806 32 17 0,000 0,04906076 0,07490965 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,04906076 0,07486286 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,04906076 0,07481613 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,04906076 0,07476946 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,04906076 0,07472284 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,04906076 0,07467628 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,04906076 0,07462979 ! steroid catabolic process GO:0006706 34 17 0,000 0,04906076 0,07458335 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,04906076 0,07453696 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,04906076 0,07449064 ! gas transport GO:0015669 26 17 0,000 0,04906076 0,07444437 ! organic cation transport GO:0015695 32 17 0,000 0,04906076 0,07439816 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,04906076 0,07435201 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,04906076 0,07430591 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,04906076 0,07425987 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,05187126 0,07846532 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,05187126 0,07841676 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,05187126 0,07836827 ! limbic system development GO:0021761 40 18 0,000 0,05187126 0,07831983 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05187126 0,07827146 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,05187126 0,07822314 ! adult walking behavior GO:0007628 36 18 0,000 0,05187126 0,07817488 ! patterning of blood vessels GO:0001569 43 18 0,000 0,05187126 0,07812669 ! heart looping GO:0001947 34 18 0,000 0,05187126 0,07807855 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,05187126 0,07803047 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,05187126 0,07798245 ! centrosome cycle GO:0007098 26 18 0,000 0,05187126 0,07793449 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,05187126 0,07788659 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,05187126 0,07783875 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,05187126 0,07779097 ! glycine metabolic process GO:0006544 30 18 0,000 0,05187126 0,07774324 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05187126 0,07769558 ! response to retinoic acid GO:0032526 31 18 0,000 0,05187126 0,07764797 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,05187126 0,07760042 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,05187126 0,07755293 ! DNA integration GO:0015074 32 18 0,000 0,05187126 0,0775055 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,05187126 0,07745812 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,05187126 0,0774108 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,05187126 0,07736355 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,05187126 0,07731634 ! neural crest cell migration GO:0001755 41 18 0,000 0,05187126 0,0772692 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,05187126 0,07722211 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,05187126 0,07717508 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,05187126 0,07712811 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,05187126 0,0770812 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,05187126 0,07703434 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,05187126 0,07698754 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,05187126 0,07694079 ! detection of bacterium GO:0016045 22 18 0,000 0,05187126 0,07689411 ! nerve development GO:0021675 34 18 0,000 0,05187126 0,07684748 ! defense response to virus GO:0051607 43 18 0,000 0,05187126 0,0768009 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,05187126 0,07675438 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,05187126 0,07670792 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,05467353 0,08080305 ! positive regulation of translation GO:0045727 31 19 0,000 0,05467353 0,08075419 ! negative regulation of defense response GO:0031348 27 19 0,000 0,05467353 0,0807054 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,05467353 0,08065667 ! neuron maturation GO:0042551 46 19 0,000 0,05467353 0,08060799 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,05467353 0,08055937 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,05467353 0,08051081 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,05467353 0,08046231 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,05467353 0,08041387 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,05467353 0,08036549 ! inositol metabolic process GO:0006020 33 19 0,000 0,05467353 0,08031716 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05467353 0,08026889 ! memory GO:0007613 34 19 0,000 0,05467353 0,08022068 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,05467353 0,08017253 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,05467353 0,08012444 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,05467353 0,0800764 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,05467353 0,08002842 ! cerebral cortex development GO:0021987 40 19 0,000 0,05467353 0,0799805 ! response to vitamin A GO:0033189 32 19 0,000 0,05467353 0,07993264 ! heme metabolic process GO:0042168 40 19 0,000 0,05467353 0,07988483 ! neuromuscular junction development GO:0007528 43 19 0,000 0,05467353 0,07983708 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,05467353 0,07978939 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,05467353 0,07974175 ! response to fungus GO:0009620 26 19 0,000 0,05467353 0,07969418 ! peptide cross-linking GO:0018149 39 19 0,000 0,05467353 0,07964665 ! protein export from nucleus GO:0006611 40 19 0,000 0,05467353 0,07959919 ! heart process GO:0003015 32 19 0,000 0,05467353 0,07955178 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,05467353 0,07950443 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,05467353 0,07945713 ! visual learning GO:0008542 38 19 0,000 0,05467353 0,07940989 ! cellular pigmentation GO:0033059 37 19 0,000 0,05467353 0,07936271 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,05467353 0,07931558 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,05467353 0,07926851 ! vitamin transport GO:0051180 31 19 0,000 0,05467353 0,07922149 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,05467353 0,07917453 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,05467353 0,07912763 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,05467353 0,07908078 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,05467353 0,07903399 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,05467353 0,07898725 ! cilium assembly GO:0042384 38 19 0,000 0,05467353 0,07894057 ! peptide hormone secretion GO:0030072 32 19 0,000 0,05467353 0,07889394 ! protein secretion GO:0009306 45 20 0,000 0,0574676 0,08287683 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,0574676 0,08282793 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,0574676 0,0827791 ! positive regulation of ossification GO:0045778 50 20 0,000 0,0574676 0,08273032 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,0574676 0,08268159 ! skin development GO:0043588 42 20 0,000 0,0574676 0,08263293 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,0574676 0,08258432 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,0574676 0,08253577 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,0574676 0,08248728 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,0574676 0,08243884 ! response to vitamin GO:0033273 36 20 0,000 0,0574676 0,08239046 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,0574676 0,08234214 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,0574676 0,08229387 ! bile acid metabolic process GO:0008206 34 20 0,000 0,0574676 0,08224566 ! response to alkaloid GO:0043279 38 20 0,000 0,0574676 0,08219751 ! retinoid metabolic process GO:0001523 34 20 0,000 0,0574676 0,08214941 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,0574676 0,08210137 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,0574676 0,08205339 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,0574676 0,08200546 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,0574676 0,08195759 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,0574676 0,08190977 ! actin filament bundle formation GO:0051017 47 20 0,000 0,0574676 0,08186201 ! body fluid secretion GO:0007589 33 20 0,000 0,0574676 0,0818143 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,0574676 0,08176666 ! peptide secretion GO:0002790 38 20 0,000 0,0574676 0,08171906 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,0574676 0,08167152 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,0574676 0,08162404 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,0574676 0,08157661 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,0574676 0,08152924 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,0574676 0,08148192 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,0574676 0,08143466 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,0574676 0,08138745 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,0574676 0,08134029 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,0574676 0,08129319 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,0574676 0,08124615 ! regulation of glucose import GO:0046324 30 20 0,000 0,0574676 0,08119916 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,0574676 0,08115222 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,0574676 0,08110534 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,0574676 0,08105851 ! negative regulation of translation GO:0017148 32 20 0,000 0,0574676 0,08101174 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,0574676 0,08096502 ! regulation of cell killing GO:0031341 46 21 0,000 0,06025349 0,08484108 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,06025349 0,08479221 ! hormone secretion GO:0046879 39 21 0,000 0,06025349 0,08474339 ! cAMP metabolic process GO:0046058 41 21 0,000 0,06025349 0,08469463 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,06025349 0,08464593 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,06025349 0,08459728 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,06025349 0,08454869 ! ovarian follicle development GO:0001541 39 21 0,000 0,06025349 0,08450016 ! smooth muscle contraction GO:0006939 48 21 0,000 0,06025349 0,08445168 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,06025349 0,08440325 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,06025349 0,08435488 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,06025349 0,08430657 ! plasma membrane fusion GO:0045026 33 21 0,000 0,06025349 0,08425831 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,06025349 0,08421011 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,06025349 0,08416196 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,06025349 0,08411387 ! sensory perception of pain GO:0019233 33 21 0,000 0,06025349 0,08406583 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,06025349 0,08401785 ! diencephalon development GO:0021536 36 21 0,000 0,06025349 0,08396992 ! collagen fibril organization GO:0030199 62 21 0,000 0,06025349 0,08392205 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,06025349 0,08387423 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,06025349 0,08382646 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,06025349 0,08377875 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,06025349 0,0837311 ! collagen catabolic process GO:0030574 29 21 0,000 0,06025349 0,0836835 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,06025349 0,08363595 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,06025349 0,08358846 ! sperm-egg recognition GO:0035036 23 21 0,000 0,06025349 0,08354102 ! actin filament-based movement GO:0030048 47 21 0,000 0,06025349 0,08349363 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,06303122 0,08729324 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,06303122 0,08724378 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,06303122 0,08719438 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,06303122 0,08714503 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,06303122 0,08709574 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,06303122 0,08704651 ! microtubule-based transport GO:0010970 59 22 0,000 0,06303122 0,08699733 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,06303122 0,08694821 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,06303122 0,08689914 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,06303122 0,08685013 ! vacuolar transport GO:0007034 41 22 0,000 0,06303122 0,08680117 ! central nervous system neuron development GO:0021954 47 22 0,000 0,06303122 0,08675227 ! fucose metabolic process GO:0006004 44 22 0,000 0,06303122 0,08670342 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,06303122 0,08665463 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,06303122 0,08660589 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,06303122 0,08655721 ! ureteric bud development GO:0001657 50 22 0,000 0,06303122 0,08650858 ! stem cell differentiation GO:0048863 57 22 0,000 0,06303122 0,08646001 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,06303122 0,08641149 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,06303122 0,08636302 ! cytolysis GO:0019835 27 22 0,000 0,06303122 0,08631461 ! renal system process GO:0003014 42 22 0,000 0,06303122 0,08626626 ! vasodilation GO:0042311 40 22 0,000 0,06303122 0,08621796 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,06303122 0,08616971 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,06303122 0,08612152 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,06303122 0,08607338 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,06303122 0,08602529 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,06303122 0,08597726 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,06303122 0,08592928 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,06303122 0,08588136 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,06303122 0,08583349 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,06303122 0,08578567 ! sarcomere organization GO:0045214 32 22 0,000 0,06303122 0,0857379 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,06303122 0,08569019 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,06303122 0,08564253 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,06303122 0,08559493 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,06303122 0,08554737 ! gut development GO:0048565 44 22 0,000 0,06303122 0,08549987 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,06303122 0,08545243 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,06303122 0,08540503 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,06303122 0,08535769 ! protein stabilization GO:0050821 41 22 0,000 0,06303122 0,0853104 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,06580082 0,08900964 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,06580082 0,08896038 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,06580082 0,08891118 ! gluconeogenesis GO:0006094 38 23 0,000 0,06580082 0,08886203 ! glycerol metabolic process GO:0006071 40 23 0,000 0,06580082 0,08881293 ! viral genome replication GO:0019079 44 23 0,000 0,06580082 0,08876389 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,06580082 0,0887149 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,06580082 0,08866597 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,06580082 0,08861709 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,06580082 0,08856827 ! regeneration GO:0031099 42 23 0,000 0,06580082 0,0885195 ! axis specification GO:0009798 43 23 0,000 0,06580082 0,08847078 ! visual behavior GO:0007632 46 23 0,000 0,06580082 0,08842211 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,06580082 0,0883735 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,06580082 0,08832495 ! response to ethanol GO:0045471 47 23 0,000 0,06580082 0,08827644 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,06580082 0,08822799 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,06580082 0,0881796 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,06580082 0,08813125 ! peroxisome organization GO:0007031 43 23 0,000 0,06580082 0,08808296 ! lysosome organization GO:0007040 47 23 0,000 0,06580082 0,08803472 ! vesicle targeting GO:0006903 49 23 0,000 0,06580082 0,08798654 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,06580082 0,08793841 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,06580082 0,08789033 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,06580082 0,0878423 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,06580082 0,08779432 ! fatty acid transport GO:0015908 47 23 0,000 0,06580082 0,0877464 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,06580082 0,08769853 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,06580082 0,08765071 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,06580082 0,08760295 ! hormone transport GO:0009914 41 23 0,000 0,06580082 0,08755523 ! cell-cell recognition GO:0009988 28 23 0,000 0,06580082 0,08750757 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,06580082 0,08745996 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,06580082 0,0874124 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,06580082 0,08736489 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,06856231 0,09098193 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,06856231 0,09093253 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,06856231 0,09088319 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,06856231 0,09083391 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,06856231 0,09078468 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,06856231 0,0907355 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,06856231 0,09068637 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,06856231 0,0906373 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,06856231 0,09058828 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,06856231 0,09053931 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,06856231 0,0904904 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,06856231 0,09044154 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,06856231 0,09039273 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,06856231 0,09034397 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,06856231 0,09029527 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,06856231 0,09024662 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,06856231 0,09019802 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,06856231 0,09014948 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,06856231 0,09010098 ! membrane depolarization GO:0051899 45 24 0,000 0,06856231 0,09005254 ! pallium development GO:0021543 56 24 0,000 0,06856231 0,09000415 ! oogenesis GO:0048477 44 24 0,000 0,06856231 0,08995581 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,06856231 0,08990753 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,06856231 0,0898593 ! platelet activation GO:0030168 41 24 0,000 0,06856231 0,08981111 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,06856231 0,08976298 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,06856231 0,0897149 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,06856231 0,08966688 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,06856231 0,0896189 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,06856231 0,08957098 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,06856231 0,0895231 ! regulation of amine transport GO:0051952 41 24 0,000 0,06856231 0,08947528 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,06856231 0,08942751 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,07131572 0,09296921 ! leukocyte adhesion GO:0007159 55 25 0,000 0,07131572 0,09291962 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,07131572 0,09287009 ! phototransduction GO:0007602 37 25 0,000 0,07131572 0,09282062 ! keratinization GO:0031424 37 25 0,000 0,07131572 0,09277119 ! vasculogenesis GO:0001570 49 25 0,000 0,07131572 0,09272182 ! vacuole organization GO:0007033 49 25 0,000 0,07131572 0,0926725 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,07131572 0,09262323 ! receptor metabolic process GO:0043112 53 25 0,000 0,07131572 0,09257401 ! chromosome condensation GO:0030261 48 25 0,000 0,07131572 0,09252485 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,07131572 0,09247574 ! regulation of behavior GO:0050795 48 25 0,000 0,07131572 0,09242668 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,07131572 0,09237768 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,07131572 0,09232872 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,07131572 0,09227982 ! immunoglobulin production GO:0002377 62 25 0,000 0,07131572 0,09223097 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,07131572 0,09218217 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,07131572 0,09213342 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,07131572 0,09208472 ! liver development GO:0001889 55 25 0,000 0,07131572 0,09203608 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,07406106 0,0955286 ! myelination GO:0042552 50 26 0,000 0,07406106 0,09547819 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,07406106 0,09542783 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,07406106 0,09537753 ! molting cycle process GO:0022404 52 26 0,000 0,07406106 0,09532728 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,07406106 0,09527708 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,07406106 0,09522693 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,07406106 0,09517684 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,07406106 0,0951268 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,07406106 0,09507681 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,07406106 0,09502687 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,07406106 0,09497699 ! digestive system process GO:0022600 49 26 0,000 0,07406106 0,09492716 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,07406106 0,09487738 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,07406106 0,09482766 ! osteoblast differentiation GO:0001649 63 26 0,000 0,07406106 0,09477798 ! neural crest cell development GO:0014032 59 26 0,000 0,07406106 0,09472836 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,07406106 0,09467879 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,07406106 0,09462927 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,07406106 0,09457981 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,07406106 0,09453039 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,07406106 0,09448103 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,07406106 0,09443172 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,07406106 0,09438246 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,07406106 0,09433325 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,07406106 0,09428409 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,07406106 0,09423498 ! blastocyst development GO:0001824 50 26 0,000 0,07406106 0,09418593 ! telomere organization GO:0032200 46 26 0,000 0,07406106 0,09413692 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,07406106 0,09408797 ! neural tube closure GO:0001843 58 26 0,000 0,07406106 0,09403907 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,07406106 0,09399022 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,07406106 0,09394142 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,07406106 0,09389267 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,07679836 0,09731245 ! embryonic pattern specification GO:0009880 49 27 0,000 0,07679836 0,097262 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,07679836 0,09721161 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,07679836 0,09716127 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,07679836 0,09711098 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,07679836 0,09706074 ! iron ion transport GO:0006826 65 27 0,000 0,07679836 0,09701055 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,07679836 0,09696042 ! superoxide metabolic process GO:0006801 41 27 0,000 0,07679836 0,09691033 ! tube lumen formation GO:0035148 59 27 0,000 0,07679836 0,0968603 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,07679836 0,09681032 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,07679836 0,09676039 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,07679836 0,09671052 ! response to toxin GO:0009636 49 27 0,000 0,07679836 0,09666069 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,07679836 0,09661092 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,07679836 0,0965612 ! leukocyte proliferation GO:0070661 59 27 0,000 0,07679836 0,09651153 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,07679836 0,0964619 ! neuron fate commitment GO:0048663 52 28 0,000 0,07952765 0,09983867 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,07952765 0,0997874 ! vesicle docking GO:0048278 55 28 0,000 0,07952765 0,09973617 ! circadian rhythm GO:0007623 56 28 0,000 0,07952765 0,099685 ! dendrite development GO:0016358 67 28 0,000 0,07952765 0,09963388 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,07952765 0,09958281 ! fat cell differentiation GO:0045444 57 28 0,000 0,07952765 0,09953179 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,07952765 0,09948083 ! sperm motility GO:0030317 37 28 0,000 0,07952765 0,09942992 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,07952765 0,09937906 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,07952765 0,09932825 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,07952765 0,0992775 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,07952765 0,09922679 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,07952765 0,09917614 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,07952765 0,09912554 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,07952765 0,09907499 ! glutathione metabolic process GO:0006749 42 28 0,000 0,07952765 0,09902449 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,07952765 0,09897405 ! lipid oxidation GO:0034440 48 28 0,000 0,07952765 0,09892366 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,07952765 0,09887331 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,07952765 0,09882302 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,08224895 0,10215261 ! translational initiation GO:0006413 66 29 0,000 0,08224895 0,10210071 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,08224895 0,10204885 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,08224895 0,10199705 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,08224895 0,1019453 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,08224895 0,1018936 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,08224895 0,10184196 ! primary neural tube formation GO:0014020 61 29 0,000 0,08224895 0,10179037 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,08224895 0,10173883 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,08224895 0,10168734 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,08224895 0,10163591 ! synaptogenesis GO:0007416 46 29 0,000 0,08224895 0,10158452 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,08224895 0,10153319 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,08224895 0,10148191 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,08224895 0,10143069 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,08224895 0,10137951 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,08496228 0,10467113 ! phenol metabolic process GO:0018958 56 30 0,000 0,08496228 0,10461837 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,08496228 0,10456567 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,08496228 0,10451302 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,08496228 0,10446042 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,08496228 0,10440787 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,08496228 0,10435538 ! acute-phase response GO:0006953 50 30 0,000 0,08496228 0,10430294 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,08496228 0,10425055 ! myofibril assembly GO:0030239 50 30 0,000 0,08496228 0,10419822 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,08496228 0,10414594 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,08496228 0,10409371 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,08496228 0,10404153 ! cell fate determination GO:0001709 64 30 0,000 0,08496228 0,1039894 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,08496228 0,10393733 ! phospholipid transport GO:0015914 65 30 0,000 0,08496228 0,10388531 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,08496228 0,10383334 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,08496228 0,10378142 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,08496228 0,10372956 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,08496228 0,10367775 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,08496228 0,10362599 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,08496228 0,10357428 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,08766766 0,106819 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,08766766 0,10676575 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,08766766 0,10671256 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,08766766 0,10665941 ! regulation of innate immune response GO:0045088 57 31 0,000 0,08766766 0,10660632 ! ovulation cycle process GO:0022602 55 31 0,000 0,08766766 0,10655328 ! peptide transport GO:0015833 60 31 0,000 0,08766766 0,1065003 ! male gonad development GO:0008584 56 31 0,000 0,08766766 0,10644737 ! iron ion homeostasis GO:0055072 60 31 0,000 0,08766766 0,10639449 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,08766766 0,10634166 ! detection of light stimulus GO:0009583 44 31 0,000 0,08766766 0,10628888 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,08766766 0,10623616 ! natural killer cell activation GO:0030101 50 31 0,000 0,08766766 0,10618349 ! ensheathment of neurons GO:0007272 64 31 0,000 0,08766766 0,10613087 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,08766766 0,10607831 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,08766766 0,10602579 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,08766766 0,10597333 ! eye morphogenesis GO:0048592 65 31 0,000 0,08766766 0,10592092 ! response to heat GO:0009408 54 31 0,000 0,08766766 0,10586856 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,08766766 0,10581625 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,09036512 0,10901827 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,09036512 0,10896446 ! collagen metabolic process GO:0032963 49 32 0,000 0,09036512 0,1089107 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,09036512 0,108857 ! spindle organization GO:0007051 50 32 0,000 0,09036512 0,10880335 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,09036512 0,10874975 ! metanephros development GO:0001656 81 32 0,000 0,09036512 0,10869621 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,09036512 0,10864271 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,09036512 0,10858927 ! muscle cell development GO:0055001 52 32 0,000 0,09036512 0,10853589 ! mesoderm formation GO:0001707 73 32 0,000 0,09036512 0,10848255 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,09036512 0,10842927 ! ovulation cycle GO:0042698 57 32 0,000 0,09036512 0,10837604 ! peripheral nervous system development GO:0007422 68 32 0,000 0,09036512 0,10832286 ! BMP signaling pathway GO:0030509 71 32 0,000 0,09036512 0,10826974 ! hindbrain development GO:0030902 65 32 0,000 0,09036512 0,10821666 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,09036512 0,10816364 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,09036512 0,10811067 ! gene silencing GO:0016458 71 32 0,000 0,09036512 0,10805776 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,09305468 0,11121947 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,09305468 0,11116508 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,09305468 0,11111075 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,09305468 0,11105647 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,09305468 0,11100224 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,09305468 0,11094807 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,09305468 0,11089395 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,09305468 0,11083988 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,09305468 0,11078586 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,09305468 0,1107319 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,09305468 0,11067799 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,09573637 0,11381214 ! glial cell differentiation GO:0010001 67 34 0,000 0,09573637 0,11375678 ! post-embryonic development GO:0009791 76 34 0,000 0,09573637 0,11370148 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,09573637 0,11364623 ! cholesterol transport GO:0030301 62 34 0,000 0,09573637 0,11359104 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,09573637 0,11353589 ! spliceosome assembly GO:0000245 75 34 0,000 0,09573637 0,11348081 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,09573637 0,11342577 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,09573637 0,11337079 ! formation of primary germ layer GO:0001704 76 34 0,000 0,09573637 0,11331586 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,09573637 0,11326099 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,09573637 0,11320617 ! adult locomotory behavior GO:0008344 62 34 0,000 0,09573637 0,1131514 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,0984102 0,11625537 ! negative regulation of secretion GO:0051048 68 35 0,000 0,0984102 0,11619918 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,0984102 0,11614305 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,0984102 0,11608697 ! membrane docking GO:0022406 69 35 0,000 0,0984102 0,11603094 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,0984102 0,11597497 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,0984102 0,11591905 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,0984102 0,11586318 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,0984102 0,11580737 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,0984102 0,11575162 ! ceramide metabolic process GO:0006672 72 35 0,000 0,0984102 0,11569591 ! telencephalon development GO:0021537 81 35 0,000 0,0984102 0,11564026 ! sterol transport GO:0015918 63 35 0,000 0,0984102 0,11558467 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,0984102 0,11552912 ! placenta development GO:0001890 53 35 0,000 0,0984102 0,11547363 ! vesicle localization GO:0051648 70 35 0,000 0,0984102 0,1154182 ! regulation of muscle development GO:0048634 82 36 0,000 0,10107619 0,11848807 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,10107619 0,11843124 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,10107619 0,11837447 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,10107619 0,11831775 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,10107619 0,11826108 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,10107619 0,11820447 ! positive regulation of cell development GO:0010720 85 36 0,000 0,10107619 0,11814791 ! protein targeting to membrane GO:0006612 75 36 0,000 0,10107619 0,11809141 ! regulation of proteolysis GO:0030162 77 36 0,000 0,10107619 0,11803496 ! aerobic respiration GO:0009060 56 36 0,000 0,10107619 0,11797857 ! embryonic organ development GO:0048568 67 36 0,000 0,10107619 0,11792223 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,10107619 0,11786594 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,10107619 0,1178097 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,10373438 0,12085031 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,10373438 0,12079271 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,10373438 0,12073516 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,10373438 0,12067767 ! sister chromatid segregation GO:0000819 65 37 0,000 0,10373438 0,12062023 ! odontogenesis GO:0042476 74 37 0,000 0,10373438 0,12056284 ! actomyosin structure organization GO:0031032 68 37 0,000 0,10373438 0,12050552 ! tissue remodeling GO:0048771 78 37 0,000 0,10373438 0,12044824 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,10373438 0,12039102 ! female gonad development GO:0008585 71 37 0,000 0,10373438 0,12033385 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,10373438 0,12027674 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,10373438 0,12021969 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,10373438 0,12016268 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,10373438 0,12010573 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,10638479 0,12311608 ! meiosis I GO:0007127 74 38 0,000 0,10638479 0,12305778 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,10638479 0,12299954 ! organic anion transport GO:0015711 82 38 0,000 0,10638479 0,12294136 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,10638479 0,12288323 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,10638479 0,12282516 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,10638479 0,12276714 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,10638479 0,12270918 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,10638479 0,12265127 ! regulation of protein stability GO:0031647 77 38 0,000 0,10638479 0,12259341 ! spermatid development GO:0007286 69 38 0,000 0,10638479 0,12253561 ! glycogen metabolic process GO:0005977 63 38 0,000 0,10638479 0,12247787 ! pigment metabolic process GO:0042440 87 38 0,000 0,10638479 0,12242018 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,10902743 0,12540207 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,10902743 0,12534306 ! negative regulation of binding GO:0051100 71 39 0,000 0,10902743 0,1252841 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,10902743 0,1252252 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,10902743 0,12516636 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,10902743 0,12510757 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,10902743 0,12504883 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,10902743 0,12499015 ! glucan metabolic process GO:0044042 64 39 0,000 0,10902743 0,12493152 GO:0006073|cellular glucan metabolic process, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,11166233 0,1278908 ! learning GO:0007612 82 40 0,000 0,11166233 0,12783087 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,11166233 0,12777099 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,11166233 0,12771117 ! mismatch repair GO:0006298 58 40 0,000 0,11166233 0,12765141 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,11166233 0,12759171 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,11166233 0,12753206 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,11166233 0,12747246 ! RNA export from nucleus GO:0006405 61 41 0,000 0,11428951 0,13041068 ! mRNA catabolic process GO:0006402 79 41 0,000 0,11428951 0,1303498 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,11428951 0,13028897 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,11428951 0,1302282 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,11428951 0,13016749 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,11428951 0,13010684 ! gliogenesis GO:0042063 91 41 0,000 0,11428951 0,13004624 ! feeding behavior GO:0007631 69 41 0,000 0,11428951 0,12998569 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,11428951 0,12992521 ! mesenchymal cell development GO:0014031 94 41 0,000 0,11428951 0,12986478 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,11428951 0,1298044 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,11428951 0,12974409 ! spermatid differentiation GO:0048515 73 41 0,000 0,11428951 0,12968382 ! RNA modification GO:0009451 64 41 0,000 0,11428951 0,12962362 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,11690899 0,13253303 ! ear morphogenesis GO:0042471 64 42 0,000 0,11690899 0,13247156 ! organic ether metabolic process GO:0018904 59 42 0,000 0,11690899 0,13241014 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,11690899 0,13234878 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,11690899 0,13228748 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,11690899 0,13222624 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,11690899 0,13216505 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,11690899 0,13210392 ! regulation of protein secretion GO:0050708 77 42 0,000 0,11690899 0,13204285 ! cytokinesis GO:0000910 84 42 0,000 0,11690899 0,13198183 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,11690899 0,13192087 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,11952081 0,13480579 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,11952081 0,13474358 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,11952081 0,13468143 ! regulation of tube size GO:0035150 76 43 0,000 0,11952081 0,13461933 GO:0050880|regulation of blood vessel size, ! glucose transport GO:0015758 66 43 0,000 0,11952081 0,1345573 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,11952081 0,13449532 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,11952081 0,13443339 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,11952081 0,13437153 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,11952081 0,13430972 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,11952081 0,13424797 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,11952081 0,13418627 ! ion transmembrane transport GO:0034220 79 43 0,000 0,11952081 0,13412464 ! neuron migration GO:0001764 85 43 0,000 0,11952081 0,13406305 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,11952081 0,13400153 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,12212497 0,13685839 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,12212497 0,13679564 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,12212497 0,13673295 ! hexose transport GO:0008645 68 44 0,000 0,12212497 0,13667031 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,12212497 0,13660774 ! striated muscle contraction GO:0006941 85 44 0,000 0,12212497 0,13654522 ! phagocytosis GO:0006909 105 44 0,000 0,12212497 0,13648275 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,12212497 0,13642035 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,1247215 0,13925714 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,1247215 0,13919352 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,1247215 0,13912997 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,1247215 0,13906646 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,1247215 0,13900302 ! female gamete generation GO:0007292 71 45 0,000 0,1247215 0,13893964 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,1247215 0,13887631 ! polyol metabolic process GO:0019751 77 45 0,000 0,1247215 0,13881304 ! developmental growth GO:0048589 88 45 0,000 0,1247215 0,13874983 ! maintenance of location in cell GO:0051651 101 45 0,000 0,1247215 0,13868667 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,12731042 0,14150108 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,12731042 0,14143673 ! glycolysis GO:0006096 71 46 0,000 0,12731042 0,14137244 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,12731042 0,14130821 ! leukocyte migration GO:0050900 75 46 0,000 0,12731042 0,14124404 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,12731042 0,14117992 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,12731042 0,14111587 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,12731042 0,14105187 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,12731042 0,14098793 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,12989176 0,14378141 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,13246554 0,146564 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,13246554 0,14649765 ! cellular component disassembly GO:0022411 89 48 0,000 0,13246554 0,14643137 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,13246554 0,14636514 ! endosome transport GO:0016197 127 48 0,000 0,13246554 0,14629897 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,13246554 0,14623286 ! male sex differentiation GO:0046661 93 48 0,000 0,13246554 0,14616681 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,13246554 0,14610082 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,13246554 0,14603489 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,13246554 0,14596902 ! response to calcium ion GO:0051592 94 49 0,000 0,13503178 0,14872977 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,13503178 0,14866275 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,13503178 0,14859578 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,13503178 0,14852888 ! JNK cascade GO:0007254 106 49 0,000 0,13503178 0,14846203 ! protein homooligomerization GO:0051260 84 49 0,000 0,13503178 0,14839525 ! regulation of action potential GO:0001508 102 50 0,000 0,13759049 0,1511392 ! regulation of ion transport GO:0043269 86 50 0,000 0,13759049 0,15107127 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,13759049 0,1510034 ! endocrine system development GO:0035270 109 50 0,000 0,13759049 0,1509356 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,13759049 0,15086785 ! regulation of ossification GO:0030278 123 50 0,000 0,13759049 0,15080017 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,13759049 0,15073255 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,13759049 0,15066498 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,13759049 0,15059748 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,14014171 0,15332119 ! peptide metabolic process GO:0006518 80 51 0,000 0,14014171 0,15325256 ! response to temperature stimulus GO:0009266 84 51 0,000 0,14014171 0,15318399 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,14014171 0,15311548 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,14014171 0,15304703 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,14268546 0,1557554 ! Notch signaling pathway GO:0007219 111 52 0,000 0,14268546 0,15568583 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,14268546 0,15561633 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,14268546 0,15554689 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,14268546 0,15547751 ! excretion GO:0007588 87 52 0,000 0,14268546 0,15540819 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,14268546 0,15533894 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,14268546 0,15526974 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,14268546 0,15520061 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,14268546 0,15513154 ! amino acid activation GO:0043038 98 52 0,000 0,14268546 0,15506253 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,14522175 0,15774866 ! inner ear development GO:0048839 89 53 0,000 0,14522175 0,15767855 ! chromatin remodeling GO:0006338 122 53 0,000 0,14522175 0,1576085 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,14522175 0,15753851 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,14522175 0,15746859 ! vesicle organization GO:0016050 127 53 0,000 0,14522175 0,15739873 ! cartilage development GO:0051216 99 53 0,000 0,14522175 0,15732893 ! synapse organization GO:0050808 102 53 0,000 0,14522175 0,15725919 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,14775061 0,15992678 ! regulation of translational initiation GO:0006446 87 54 0,000 0,14775061 0,15985595 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,14775061 0,15978519 ! neuromuscular process GO:0050905 107 54 0,000 0,14775061 0,15971448 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,14775061 0,15964385 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,14775061 0,15957327 ! membrane fusion GO:0006944 122 54 0,000 0,14775061 0,15950276 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,14775061 0,1594323 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,14775061 0,15936191 ! RNA catabolic process GO:0006401 103 55 0,000 0,15027206 0,16200999 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,15027206 0,16193852 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,15027206 0,16186712 ! cell recognition GO:0008037 98 55 0,000 0,15027206 0,16179578 ! cell maturation GO:0048469 107 55 0,000 0,15027206 0,16172451 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,15027206 0,1616533 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,15027206 0,16158214 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,15278612 0,16421315 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,15278612 0,16414093 ! glucose catabolic process GO:0006007 88 56 0,000 0,15278612 0,16406878 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,15278612 0,1639967 ! RNA elongation GO:0006354 90 56 0,000 0,15278612 0,16392467 ! chloride transport GO:0006821 102 57 0,000 0,15529281 0,16654097 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,15529281 0,16646789 ! muscle fiber development GO:0048747 131 57 0,000 0,15529281 0,16639488 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,15529281 0,16632193 ! regulation of actin filament length GO:0030832 118 58 0,000 0,15779215 0,16892473 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,15779215 0,16885073 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,15779215 0,16877681 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,15779215 0,16870294 ! gastrulation GO:0007369 122 58 0,000 0,15779215 0,16862914 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,15779215 0,16855541 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,15779215 0,16848174 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,15779215 0,16840814 ! maintenance of location GO:0051235 124 58 0,000 0,15779215 0,1683346 ! nuclear export GO:0051168 110 59 0,000 0,16028417 0,17091848 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,16276889 0,17349232 ! DNA catabolic process GO:0006308 94 60 0,000 0,16276889 0,17341666 ! regulation of endocytosis GO:0030100 104 60 0,000 0,16276889 0,17334106 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,16276889 0,17326553 ! adult behavior GO:0030534 104 60 0,000 0,16276889 0,17319007 ! kidney development GO:0001822 133 60 0,000 0,16276889 0,17311467 ! positive regulation of secretion GO:0051047 110 61 0,000 0,16524632 0,17567309 ! regulation of cellular component size GO:0032535 125 61 0,000 0,16524632 0,17559668 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,16524632 0,17552033 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,16524632 0,17544405 ! regulation of heart contraction GO:0008016 123 61 0,000 0,16524632 0,17536784 ! camera-type eye development GO:0043010 126 61 0,000 0,16524632 0,17529169 ! proton transport GO:0015992 117 61 0,000 0,16524632 0,17521561 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,16524632 0,17513959 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,16771649 0,17768057 ! tRNA processing GO:0008033 102 62 0,000 0,16771649 0,17760355 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,16771649 0,1775266 ! regulation of mitosis GO:0007088 112 63 0,000 0,17017943 0,18005558 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,17017943 0,17997764 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,17017943 0,17989976 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,17017943 0,17982195 ! hydrogen transport GO:0006818 121 64 0,000 0,17263514 0,18233794 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,17263514 0,18225914 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,17263514 0,18218041 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,17508365 0,18468453 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,17508365 0,18460482 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,17508365 0,18452518 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,17508365 0,18444561 ! ear development GO:0043583 114 66 0,000 0,17752499 0,18693688 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,17752499 0,18685634 ! gonad development GO:0008406 115 66 0,000 0,17752499 0,18677586 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,17752499 0,18669546 ! chromosome segregation GO:0007059 127 67 0,000 0,17995917 0,18917395 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,17995917 0,18909259 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,17995917 0,18901129 ! secondary metabolic process GO:0019748 125 67 0,000 0,17995917 0,18893006 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,18238622 0,19139585 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,18238622 0,19131367 ! hexose catabolic process GO:0019320 113 68 0,000 0,18238622 0,19123156 ! extracellular matrix organization GO:0030198 146 68 0,000 0,18238622 0,19114952 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,18238622 0,19106755 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,18238622 0,19098565 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,18238622 0,19090383 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,18480615 0,19335393 ! urogenital system development GO:0001655 149 69 0,000 0,18480615 0,19327116 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,18480615 0,19318846 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,18480615 0,19310583 ! developmental maturation GO:0021700 128 69 0,000 0,18480615 0,19302327 ! single fertilization GO:0007338 83 69 0,000 0,18480615 0,19294078 ! cell redox homeostasis GO:0045454 114 70 0,000 0,18721899 0,19537633 ! germ cell development GO:0007281 133 70 0,000 0,18721899 0,1952929 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,18962475 0,19771799 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,18962475 0,19763364 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,18962475 0,19754936 ! carbohydrate transport GO:0008643 114 72 0,000 0,19202346 0,19996304 ! actin filament organization GO:0007015 167 72 0,000 0,19202346 0,19987785 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,19202346 0,19979272 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,19202346 0,19970766 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,19202346 0,19962268 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,19441513 0,20202304 ! regulation of immune effector process GO:0002697 156 73 0,000 0,19441513 0,20193715 ! amino acid transport GO:0006865 148 74 0,000 0,1967998 0,2043272 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,1967998 0,2042404 ! transition metal ion transport GO:0000041 143 75 0,000 0,19917747 0,20662019 ! reproductive structure development GO:0048608 131 75 0,000 0,19917747 0,20653249 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,19917747 0,20644487 ! axon guidance GO:0007411 162 75 0,000 0,19917747 0,20635732 ! rhythmic process GO:0048511 142 75 0,000 0,19917747 0,20626984 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,20154817 0,20863651 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,20154817 0,20854815 ! learning or memory GO:0007611 161 76 0,000 0,20154817 0,20845985 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,20154817 0,20837164 ! regulation of blood pressure GO:0008217 134 76 0,000 0,20154817 0,20828349 ! amine catabolic process GO:0009310 136 77 0,000 0,20391192 0,21063713 ! neurotransmitter transport GO:0006836 142 77 0,000 0,20391192 0,2105481 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,20391192 0,21045915 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,20391192 0,21037028 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,20391192 0,21028147 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,20626873 0,21262216 ! antigen processing and presentation GO:0019882 117 78 0,000 0,20626873 0,21253248 ! fertilization GO:0009566 99 78 0,000 0,20626873 0,21244288 ! blood coagulation GO:0007596 151 79 0,000 0,20861864 0,21477258 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,20861864 0,21468211 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,20861864 0,21459172 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,20861864 0,21450141 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,21096166 0,21681924 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,21096166 0,21672806 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,21096166 0,21663696 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,21096166 0,21654594 ! meiosis GO:0007126 143 81 0,000 0,2132978 0,21885196 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,2132978 0,21876009 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,2132978 0,21866829 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,21562709 0,2209635 ! meiotic cell cycle GO:0051321 144 82 0,000 0,21562709 0,22087086 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,21794956 0,22315623 ! exocytosis GO:0006887 153 83 0,000 0,21794956 0,22306274 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,21794956 0,22296933 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,21794956 0,222876 ! inorganic anion transport GO:0015698 156 83 0,000 0,21794956 0,22278275 ! response to metal ion GO:0010038 158 84 0,000 0,22026521 0,22505558 ! response to nutrient GO:0007584 135 84 0,000 0,22026521 0,2249615 ! digestion GO:0007586 130 84 0,000 0,22026521 0,22486749 ! hemostasis GO:0007599 165 85 0,000 0,22257407 0,22712968 ! negative regulation of transport GO:0051051 164 85 0,000 0,22257407 0,22703484 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,22257407 0,22694009 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,22257407 0,22684541 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,22257407 0,22675081 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,22257407 0,22665629 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,22487615 0,22890519 ! regulation of lyase activity GO:0051339 169 86 0,000 0,22487615 0,22880985 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,22717149 0,2310491 ! alcohol catabolic process GO:0046164 142 87 0,000 0,22717149 0,23095295 ! nucleosome assembly GO:0006334 126 87 0,000 0,22717149 0,23085688 ! regulation of protein transport GO:0051223 165 87 0,000 0,22717149 0,23076089 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,22946009 0,23298878 ! amine biosynthetic process GO:0009309 146 88 0,000 0,22946009 0,23289198 ! sensory perception of smell GO:0007608 117 88 0,000 0,22946009 0,23279527 ! chromatin assembly GO:0031497 128 88 0,000 0,22946009 0,23269863 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,23174198 0,23491521 ! cellular defense response GO:0006968 123 89 0,000 0,23174198 0,23481778 ! regulation of neurological system process GO:0031644 175 89 0,000 0,23174198 0,23472042 ! response to inorganic substance GO:0010035 173 90 0,000 0,23401718 0,23692663 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,23401718 0,23682849 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,23401718 0,23673042 ! response to unfolded protein GO:0006986 139 90 0,000 0,23401718 0,23663244 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,23401718 0,23653453 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,2362857 0,23872869 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,2362857 0,23863 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,23854757 0,24081476 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,23854757 0,24071529 ! amine transport GO:0015837 181 93 0,000 0,2408028 0,24289069 ! vitamin metabolic process GO:0006766 153 93 0,000 0,2408028 0,24279044 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,24305142 0,24495652 ! female pregnancy GO:0007565 166 94 0,000 0,24305142 0,24485551 ! sterol metabolic process GO:0016125 166 94 0,000 0,24305142 0,24475458 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,24305142 0,24465374 ! regulation of membrane potential GO:0042391 179 94 0,000 0,24305142 0,24455297 ! nucleosome organization GO:0034728 143 95 0,000 0,24529344 0,24670723 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,24529344 0,24660571 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,24529344 0,24650427 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,24529344 0,24640291 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,24529344 0,24630163 ! sex differentiation GO:0007548 171 96 0,000 0,24752888 0,24844415 ! response to protein stimulus GO:0051789 158 96 0,000 0,24752888 0,24834212 ! regulation of T cell activation GO:0050863 175 96 0,000 0,24752888 0,24824017 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,24975776 0,25037268 ! transcription initiation GO:0006352 171 97 0,000 0,24975776 0,25026998 ! regulation of protein localization GO:0032880 188 97 0,000 0,24975776 0,25016737 ! forebrain development GO:0030900 210 98 0,000 0,25198011 0,25228992 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,25198011 0,25218656 ! mRNA transport GO:0051028 185 100 0,000 0,25640525 0,25651025 ! hormone metabolic process GO:0042445 171 100 0,000 0,25640525 0,25640525