pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1096-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 5,000 1,008E-10 2,425E-07 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 4,000 3,717E-08 4,471E-05 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 4,588E-08 3,679E-05 ! positive regulation of cellular catabolic process GO:0031331 31 12 3,000 9,752E-08 5,866E-05 ! protein amino acid autophosphorylation GO:0046777 141 60 5,000 1,15E-07 5,534E-05 ! regulation of protein complex assembly GO:0043254 117 61 5,000 1,271E-07 5,098E-05 ! regulation of vasodilation GO:0042312 26 15 3,000 2,665E-07 9,162E-05 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 2,94E-07 8,842E-05 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 4,62E-07 1,235E-04 ! positive regulation of glycolysis GO:0045821 14 5 2,000 5,393E-07 1,298E-04 ! positive regulation of vasoconstriction GO:0045907 9 5 2,000 5,393E-07 1,18E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 6,375E-07 1,278E-04 ! response to insulin stimulus GO:0032868 95 46 4,000 8,996E-07 1,665E-04 ! nuclear migration GO:0007097 12 6 2,000 1,076E-06 1,849E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 1,076E-06 1,725E-04 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of microtubule polymerization GO:0031116 13 6 2,000 1,076E-06 1,618E-04 ! positive regulation of cell cycle GO:0045787 89 48 4,000 1,117E-06 1,581E-04 ! positive regulation of DNA replication GO:0045740 43 23 3,000 1,689E-06 2,257E-04 ! myeloid leukocyte differentiation GO:0002573 40 23 3,000 1,689E-06 2,139E-04 ! positive regulation of protein ubiquitination GO:0031398 12 7 2,000 1,877E-06 2,258E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 1,877E-06 2,151E-04 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 2,000 1,877E-06 2,053E-04 ! macrophage differentiation GO:0030225 11 7 2,000 1,877E-06 1,964E-04 ! muscle adaptation GO:0043500 14 7 2,000 1,877E-06 1,882E-04 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 2,000 1,877E-06 1,807E-04 ! regulation of microtubule polymerization GO:0031113 15 7 2,000 1,877E-06 1,737E-04 ! regulation of cellular catabolic process GO:0031329 52 24 3,000 2,021E-06 1,801E-04 ! vasculogenesis GO:0001570 46 25 3,000 2,398E-06 2,061E-04 ! regulation of DNA replication GO:0006275 101 56 4,000 2,432E-06 2,018E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 2,995E-06 2,402E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 2,995E-06 2,325E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 2,995E-06 2,252E-04 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 3,73E-06 2,72E-04 ! regulation of lipid metabolic process GO:0019216 115 63 4,000 4,381E-06 3,1E-04 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 4,48E-06 3,08E-04 ! regulation of epithelial cell differentiation GO:0030856 14 9 2,000 4,48E-06 2,994E-04 ! regulation of glycolysis GO:0006110 21 9 2,000 4,48E-06 2,913E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 4,48E-06 2,837E-04 ! gas homeostasis GO:0033483 16 9 2,000 4,48E-06 2,764E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 5,946E-06 3,577E-04 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 6,382E-06 3,745E-04 ! negative regulation of MAPKKK cascade GO:0043409 20 10 2,000 6,382E-06 3,656E-04 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 2,000 6,382E-06 3,571E-04 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of catabolic process GO:0009896 64 32 3,000 6,679E-06 3,652E-04 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 2,000 8,751E-06 4,679E-04 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 8,751E-06 4,577E-04 ! nucleus localization GO:0051647 19 11 2,000 8,751E-06 4,48E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 1,164E-05 5,833E-04 ! gland morphogenesis GO:0022612 29 12 2,000 1,164E-05 5,713E-04 ! protein oligomerization GO:0051259 139 78 4,000 1,257E-05 6,049E-04 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 1,338E-05 6,312E-04 ! positive regulation of DNA metabolic process GO:0051054 72 38 3,000 1,347E-05 6,232E-04 ! mammary gland development GO:0030879 86 39 3,000 1,496E-05 6,793E-04 ! lipid localization GO:0010876 28 13 2,000 1,508E-05 6,721E-04 GO:0019915|lipid storage, ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 2,000 1,508E-05 6,599E-04 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cytokine production during immune response GO:0002718 23 13 2,000 1,508E-05 6,481E-04 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 1,508E-05 6,367E-04 ! positive regulation of protein polymerization GO:0032273 25 13 2,000 1,508E-05 6,257E-04 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 1,512E-05 6,165E-04 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 4,000 1,512E-05 6,063E-04 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 1,605E-05 6,331E-04 ! response to oxygen levels GO:0070482 176 83 4,000 1,703E-05 6,608E-04 ! regulation of JAK-STAT cascade GO:0046425 70 45 3,000 2,663E-05 1,017E-03 ! cell growth GO:0016049 84 45 3,000 2,663E-05 1,001E-03 ! regulation of protein ubiquitination GO:0031396 25 16 2,000 2,929E-05 1,084E-03 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 2,929E-05 1,068E-03 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 2,000 2,929E-05 1,052E-03 ! filopodium assembly GO:0046847 32 16 2,000 2,929E-05 1,036E-03 ! positive regulation of protein complex assembly GO:0031334 32 17 2,000 3,547E-05 1,237E-03 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 2,000 3,547E-05 1,219E-03 ! microspike assembly GO:0030035 36 17 2,000 3,547E-05 1,202E-03 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 3,623E-05 1,211E-03 ! skeletal muscle tissue development GO:0007519 186 99 4,000 3,996E-05 1,317E-03 GO:0060538|skeletal muscle organ development, ! positive regulation of anti-apoptosis GO:0045768 39 18 2,000 4,244E-05 1,38E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 4,244E-05 1,362E-03 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 3,000 4,389E-05 1,389E-03 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 3,000 4,389E-05 1,371E-03 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 2,000 5,026E-05 1,55E-03 ! regulation of protein polymerization GO:0032271 103 53 3,000 5,113E-05 1,557E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 5,897E-05 1,773E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of fatty acid metabolic process GO:0019217 38 20 2,000 5,897E-05 1,751E-03 ! regulation of interleukin-2 production GO:0032663 35 20 2,000 5,897E-05 1,73E-03 ! inner ear receptor cell differentiation GO:0060113 37 20 2,000 5,897E-05 1,709E-03 ! aging GO:0007568 103 55 3,000 5,92E-05 1,696E-03 ! positive regulation of organelle organization GO:0010638 100 56 3,000 6,357E-05 1,799E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 6,816E-05 1,907E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 6,816E-05 1,885E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 6,86E-05 1,876E-03 ! cell aging GO:0007569 44 21 2,000 6,86E-05 1,855E-03 ! regulation of vasoconstriction GO:0019229 39 21 2,000 6,86E-05 1,834E-03 ! mechanoreceptor differentiation GO:0042490 40 22 2,000 7,921E-05 2,094E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 7,921E-05 2,072E-03 ! positive regulation of cytoskeleton organization GO:0051495 48 22 2,000 7,921E-05 2,049E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 7,921E-05 2,028E-03 ! regulation of anti-apoptosis GO:0045767 53 23 2,000 9,084E-05 2,301E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 9,084E-05 2,277E-03 ! sex determination GO:0007530 47 23 2,000 9,084E-05 2,253E-03 ! membrane depolarization GO:0051899 39 24 2,000 1,035E-04 2,542E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 1,035E-04 2,516E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 1,074E-04 2,584E-03 ! myeloid cell differentiation GO:0030099 111 65 3,000 1,141E-04 2,718E-03 ! regulation of smooth muscle contraction GO:0006940 43 25 2,000 1,173E-04 2,767E-03 ! interaction with host GO:0051701 62 25 2,000 1,173E-04 2,741E-03 ! regulation of blood coagulation GO:0030193 40 25 2,000 1,173E-04 2,714E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 1,284E-04 2,943E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 1,323E-04 3,002E-03 ! regulation of cellular ketone metabolic process GO:0010565 44 26 2,000 1,323E-04 2,974E-03 ! cellular response to oxidative stress GO:0034599 39 26 2,000 1,323E-04 2,946E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 1,361E-04 3,003E-03 ! protein maturation by protein folding GO:0022417 13 5 1,000 1,435E-04 3,138E-03 ! positive regulation of muscle cell differentiation GO:0051149 13 5 1,000 1,435E-04 3,11E-03 ! lipoprotein particle clearance GO:0034381 10 5 1,000 1,435E-04 3,082E-03 ! anagen GO:0042640 6 5 1,000 1,435E-04 3,055E-03 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 1,435E-04 3,028E-03 ! response to food GO:0032094 6 5 1,000 1,435E-04 3,001E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,435E-04 2,976E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 1,435E-04 2,95E-03 ! regulation of leukocyte degranulation GO:0043300 7 5 1,000 1,435E-04 2,925E-03 ! skeletal muscle regeneration GO:0043403 8 5 1,000 1,435E-04 2,901E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 1,435E-04 2,876E-03 ! regulation of muscle cell apoptosis GO:0010660 8 5 1,000 1,435E-04 2,853E-03 ! porphyrin catabolic process GO:0006787 12 5 1,000 1,435E-04 2,829E-03 GO:0033015|tetrapyrrole catabolic process, ! somatic stem cell maintenance GO:0035019 15 5 1,000 1,435E-04 2,806E-03 ! sequestering of calcium ion GO:0051208 7 5 1,000 1,435E-04 2,784E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 1,484E-04 2,856E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 1,484E-04 2,833E-03 ! regulation of MAPKKK cascade GO:0043408 142 71 3,000 1,609E-04 3,048E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 1,699E-04 3,193E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 1,699E-04 3,168E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 1,843E-04 3,411E-03 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 2,000 1,843E-04 3,385E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 1,843E-04 3,36E-03 ! negative regulation of neuron apoptosis GO:0043524 56 29 2,000 1,843E-04 3,334E-03 ! regulation of coagulation GO:0050818 46 29 2,000 1,843E-04 3,31E-03 ! phosphoinositide-mediated signaling GO:0048015 131 75 3,000 1,989E-04 3,546E-03 ! negative regulation of protein kinase cascade GO:0010741 68 30 2,000 2,042E-04 3,613E-03 ! regulation of catabolic process GO:0009894 161 76 3,000 2,094E-04 3,677E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 2,147E-04 3,742E-03 ! male sex determination GO:0030238 15 6 1,000 2,147E-04 3,715E-03 ! positive regulation of cytokine production during immune response GO:0002720 9 6 1,000 2,147E-04 3,689E-03 ! hair follicle maturation GO:0048820 7 6 1,000 2,147E-04 3,663E-03 ! regulation of interleukin-13 production GO:0032656 11 6 1,000 2,147E-04 3,637E-03 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 1,000 2,147E-04 3,612E-03 ! regulation of mast cell activation GO:0033003 12 6 1,000 2,147E-04 3,586E-03 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 2,147E-04 3,562E-03 GO:0043011|myeloid dendritic cell differentiation, ! cholesterol homeostasis GO:0042632 53 31 2,000 2,255E-04 3,716E-03 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 43 31 2,000 2,255E-04 3,691E-03 ! cholesterol transport GO:0030301 56 32 2,000 2,481E-04 4,034E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 2,481E-04 4,007E-03 ! sterol transport GO:0015918 57 33 2,000 2,722E-04 4,366E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 2,977E-04 4,743E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 2,998E-04 4,745E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,998E-04 4,714E-03 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 2,998E-04 4,683E-03 GO:0031958|corticosteroid receptor signaling pathway, ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 1,000 2,998E-04 4,653E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 2,998E-04 4,623E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! vesicle fusion GO:0006906 17 7 1,000 2,998E-04 4,594E-03 ! regulation of interleukin-10 production GO:0032653 13 7 1,000 2,998E-04 4,565E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 2,998E-04 4,536E-03 ! regulation of meiosis GO:0040020 12 7 1,000 2,998E-04 4,508E-03 GO:0051445|regulation of meiotic cell cycle, ! regulation of respiratory burst GO:0060263 11 7 1,000 2,998E-04 4,48E-03 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 1,000 2,998E-04 4,452E-03 ! regulation of myoblast differentiation GO:0045661 16 7 1,000 2,998E-04 4,425E-03 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 3,247E-04 4,764E-03 ! neutral lipid metabolic process GO:0006638 50 35 2,000 3,247E-04 4,735E-03 GO:0006639|acylglycerol metabolic process, ! regulation of microtubule-based process GO:0032886 78 35 2,000 3,247E-04 4,706E-03 ! positive regulation of protein modification process GO:0031401 136 88 3,000 3,674E-04 5,293E-03 ! regulation of DNA binding GO:0051101 155 88 3,000 3,674E-04 5,262E-03 ! gland development GO:0048732 206 88 3,000 3,674E-04 5,231E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 3,833E-04 5,425E-03 ! tissue remodeling GO:0048771 76 37 2,000 3,833E-04 5,394E-03 ! glycerol ether metabolic process GO:0006662 53 37 2,000 3,833E-04 5,362E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 3,987E-04 5,545E-03 ! positive regulation of vasodilation GO:0045909 13 8 1,000 3,987E-04 5,513E-03 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 1,000 3,987E-04 5,481E-03 ! regulation of interleukin-4 production GO:0032673 17 8 1,000 3,987E-04 5,45E-03 ! regulation of Rac protein signal transduction GO:0035020 11 8 1,000 3,987E-04 5,419E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 1,000 3,987E-04 5,389E-03 ! lipid homeostasis GO:0055088 67 38 2,000 4,15E-04 5,579E-03 ! organic ether metabolic process GO:0018904 55 39 2,000 4,484E-04 5,993E-03 ! negative regulation of multicellular organismal process GO:0051241 166 93 3,000 4,533E-04 6,026E-03 ! cytokinesis GO:0000910 72 40 2,000 4,834E-04 6,39E-03 ! regulation of Rho protein signal transduction GO:0035023 213 95 3,000 4,914E-04 6,461E-03 ! leukocyte differentiation GO:0002521 202 96 3,000 5,113E-04 6,686E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 5,113E-04 6,65E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 5,113E-04 6,614E-03 ! induction of an organ GO:0001759 14 9 1,000 5,113E-04 6,579E-03 ! response to reactive oxygen species GO:0000302 67 42 2,000 5,586E-04 7,148E-03 ! regulation of leukocyte mediated immunity GO:0002703 79 42 2,000 5,586E-04 7,11E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 6,375E-04 8,073E-03 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 6,375E-04 8,031E-03 ! glucan biosynthetic process GO:0009250 14 10 1,000 6,375E-04 7,989E-03 GO:0005978|glycogen biosynthetic process, ! multicellular organism growth GO:0035264 18 10 1,000 6,375E-04 7,948E-03 ! positive regulation of phagocytosis GO:0050766 13 10 1,000 6,375E-04 7,907E-03 ! response to nicotine GO:0035094 20 10 1,000 6,375E-04 7,866E-03 ! negative regulation of immune effector process GO:0002698 20 10 1,000 6,375E-04 7,826E-03 ! localization within membrane GO:0051668 20 10 1,000 6,375E-04 7,787E-03 ! JAK-STAT cascade GO:0007259 71 44 2,000 6,408E-04 7,787E-03 ! developmental growth GO:0048589 82 44 2,000 6,408E-04 7,748E-03 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 2,000 6,847E-04 8,237E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 7,304E-04 8,743E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 7,304E-04 8,7E-03 ! negative regulation of cell migration GO:0030336 115 46 2,000 7,304E-04 8,657E-03 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 7,773E-04 9,167E-03 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 7,773E-04 9,123E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 7,773E-04 9,078E-03 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 7,773E-04 9,034E-03 ! neuroblast proliferation GO:0007405 24 11 1,000 7,773E-04 8,991E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 7,773E-04 8,948E-03 ! developmental induction GO:0031128 19 11 1,000 7,773E-04 8,905E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! sequestering of metal ion GO:0051238 14 11 1,000 7,773E-04 8,863E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 7,773E-04 8,821E-03 ! positive regulation of DNA binding GO:0043388 73 47 2,000 7,781E-04 8,789E-03 ! protein homooligomerization GO:0051260 76 47 2,000 7,781E-04 8,748E-03 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 9,304E-04 0,01041193 ! virus-host interaction GO:0019048 29 12 1,000 9,304E-04 0,01036373 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 1,000 9,304E-04 0,01031597 ! entry into host cell GO:0030260 32 12 1,000 9,304E-04 0,01026865 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 16 12 1,000 9,304E-04 0,01022176 ! histone acetylation GO:0016573 26 12 1,000 9,304E-04 0,0101753 ! peptidyl-lysine modification GO:0018205 21 12 1,000 9,304E-04 0,01012926 ! T cell homeostasis GO:0043029 25 12 1,000 9,304E-04 0,01008363 ! regulation of cell projection organization GO:0031344 121 50 2,000 9,327E-04 0,01006312 ! inner ear development GO:0048839 79 50 2,000 9,327E-04 0,01001819 ! positive regulation of binding GO:0051099 78 51 2,000 9,883E-04 0,01056769 ! vesicle organization GO:0016050 107 51 2,000 9,883E-04 0,01052093 ! regulation of muscle contraction GO:0006937 81 52 2,000 1,046E-03 0,01108512 ! positive regulation of growth GO:0045927 90 52 2,000 1,046E-03 0,0110365 ! regulation of chemokine production GO:0032642 18 13 1,000 1,097E-03 0,01152392 ! organelle fusion GO:0048284 32 13 1,000 1,097E-03 0,01147382 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 1,000 1,097E-03 0,01142415 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 1,000 1,097E-03 0,01137491 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,097E-03 0,01132609 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,097E-03 0,01127769 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 1,106E-03 0,01131881 ! response to UV GO:0009411 104 53 2,000 1,106E-03 0,01127085 ! negative regulation of cell motion GO:0051271 134 55 2,000 1,231E-03 0,01249963 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,276E-03 0,01290391 ! myotube differentiation GO:0014902 25 14 1,000 1,276E-03 0,01284992 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 1,276E-03 0,01279638 ! stem cell development GO:0048864 43 14 1,000 1,276E-03 0,01274328 GO:0019827|stem cell maintenance, ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 1,469E-03 0,01460653 ! sulfate transport GO:0008272 23 15 1,000 1,469E-03 0,01454642 ! regulation of exocytosis GO:0017157 22 15 1,000 1,469E-03 0,0144868 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 1,469E-03 0,01442767 ! tissue regeneration GO:0042246 26 15 1,000 1,469E-03 0,01436902 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,469E-03 0,01431085 ! water homeostasis GO:0030104 27 15 1,000 1,469E-03 0,01425314 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 1,469E-03 0,0141959 ! lymphocyte homeostasis GO:0002260 30 15 1,000 1,469E-03 0,01413912 ! establishment of organelle localization GO:0051656 109 59 2,000 1,509E-03 0,01446386 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 1,000 1,675E-03 0,0159908 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 1,000 1,675E-03 0,01592759 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 1,675E-03 0,01586488 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 1,675E-03 0,01580267 ! ear development GO:0043583 103 62 2,000 1,741E-03 0,01636178 ! viral reproductive process GO:0022415 126 62 2,000 1,741E-03 0,01629812 ! signal complex assembly GO:0007172 41 17 1,000 1,893E-03 0,01765734 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 1,893E-03 0,01758916 ! myoblast differentiation GO:0045445 45 17 1,000 1,893E-03 0,01752151 ! regulation of survival gene product expression GO:0045884 33 17 1,000 1,893E-03 0,01745438 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 1,994E-03 0,01831163 ! cell projection assembly GO:0030031 120 66 2,000 2,083E-03 0,01905791 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,125E-03 0,01936469 ! positive regulation of proteolysis GO:0045862 31 18 1,000 2,125E-03 0,01929161 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 2,125E-03 0,01921909 ! lung development GO:0030324 144 67 2,000 2,175E-03 0,0195981 ! homeostasis of number of cells GO:0048872 114 67 2,000 2,175E-03 0,01952497 ! viral reproduction GO:0016032 134 68 2,000 2,269E-03 0,02029402 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 2,369E-03 0,02110924 ! lipid phosphorylation GO:0046834 35 19 1,000 2,369E-03 0,02103135 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 2,369E-03 0,02095403 ! heme metabolic process GO:0042168 36 19 1,000 2,369E-03 0,02087727 ! response to lipopolysaccharide GO:0032496 30 19 1,000 2,369E-03 0,02080108 ! protein export from nucleus GO:0006611 36 19 1,000 2,369E-03 0,02072544 ! visual learning GO:0008542 36 19 1,000 2,369E-03 0,02065035 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 2,369E-03 0,0205758 ! respiratory tube development GO:0030323 150 70 2,000 2,465E-03 0,02133064 ! regulation of immune effector process GO:0002697 137 71 2,000 2,566E-03 0,02213066 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,626E-03 0,02256075 ! response to alkaloid GO:0043279 38 20 1,000 2,626E-03 0,02248046 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,626E-03 0,02240074 ! stem cell differentiation GO:0048863 53 20 1,000 2,626E-03 0,02232159 ! peptidyl-serine modification GO:0018209 43 20 1,000 2,626E-03 0,02224299 ! negative regulation of translation GO:0017148 29 20 1,000 2,626E-03 0,02216495 ! respiratory system development GO:0060541 153 72 2,000 2,67E-03 0,02246551 ! regulation of transcription factor activity GO:0051090 126 74 2,000 2,887E-03 0,02419916 GO:0090046|regulation of transcription regulator activity, ! organelle localization GO:0051640 136 74 2,000 2,887E-03 0,02411513 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 2,895E-03 0,02409891 ! collagen catabolic process GO:0030574 28 21 1,000 2,895E-03 0,02401581 ! cell-matrix adhesion GO:0007160 163 75 2,000 2,999E-03 0,02479243 ! regulation of vesicle-mediated transport GO:0060627 119 75 2,000 2,999E-03 0,02470752 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 3,176E-03 0,02608185 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 3,176E-03 0,02599314 ! regeneration GO:0031099 41 22 1,000 3,176E-03 0,02590503 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 3,176E-03 0,02581751 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 3,176E-03 0,02573058 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 3,176E-03 0,02564424 ! protein stabilization GO:0050821 39 22 1,000 3,176E-03 0,02555847 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 3,47E-03 0,02782992 ! visual behavior GO:0007632 42 23 1,000 3,47E-03 0,02773746 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 3,47E-03 0,02764562 GO:0010810|regulation of cell-substrate adhesion, ! platelet activation GO:0030168 37 23 1,000 3,47E-03 0,02755438 ! negative regulation of cytokine production GO:0001818 40 23 1,000 3,47E-03 0,02746374 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 3,47E-03 0,02737369 ! activation of protein kinase activity GO:0032147 147 79 2,000 3,473E-03 0,02730824 ! regulation of peptidase activity GO:0052547 134 79 2,000 3,473E-03 0,02721928 ! muscle cell differentiation GO:0042692 159 80 2,000 3,598E-03 0,02811032 ! cell-substrate adhesion GO:0031589 171 81 2,000 3,727E-03 0,02901688 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 3,776E-03 0,02930751 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 3,776E-03 0,02921328 ! vesicle docking GO:0048278 47 24 1,000 3,776E-03 0,02911964 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 3,776E-03 0,02902661 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 3,776E-03 0,02893417 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 1,000 3,776E-03 0,02884231 ! leukocyte homeostasis GO:0001776 44 24 1,000 3,776E-03 0,02875104 ! porphyrin metabolic process GO:0006778 46 24 1,000 3,776E-03 0,02866034 GO:0033013|tetrapyrrole metabolic process, ! protein tetramerization GO:0051262 52 24 1,000 3,776E-03 0,02857022 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 4,094E-03 0,03088029 ! somitogenesis GO:0001756 43 25 1,000 4,094E-03 0,03078379 ! proteoglycan biosynthetic process GO:0030166 50 25 1,000 4,094E-03 0,03068789 ! cellular response to nutrient levels GO:0031669 41 25 1,000 4,094E-03 0,03059258 ! nucleosome assembly GO:0006334 122 85 2,000 4,267E-03 0,03178282 ! chromatin assembly GO:0031497 124 86 2,000 4,409E-03 0,03273962 ! initiation of viral infection GO:0019059 57 26 1,000 4,424E-03 0,03275445 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 4,424E-03 0,03265397 ! molting cycle process GO:0022404 50 26 1,000 4,424E-03 0,03255412 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 1,000 4,424E-03 0,03245487 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 4,424E-03 0,03235622 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 4,424E-03 0,03225817 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 1,000 4,424E-03 0,03216071 GO:0045840|positive regulation of mitosis, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 4,767E-03 0,03454293 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 4,767E-03 0,0344392 ! protein amino acid acylation GO:0043543 55 27 1,000 4,767E-03 0,03433609 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 4,767E-03 0,03423359 ! base-excision repair GO:0006284 41 27 1,000 4,767E-03 0,0341317 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 4,767E-03 0,03403042 ! regulation of cell cycle process GO:0010564 149 90 2,000 5,006E-03 0,03563166 ! protein-DNA complex assembly GO:0065004 130 90 2,000 5,006E-03 0,03552655 ! negative regulation of protein modification process GO:0031400 60 28 1,000 5,12E-03 0,03623458 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 5,12E-03 0,03612832 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 5,12E-03 0,03602268 ! nucleosome organization GO:0034728 138 92 2,000 5,321E-03 0,0373271 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 5,484E-03 0,03835352 ! regulation of membrane potential GO:0042391 164 93 2,000 5,484E-03 0,03824235 ! response to organic cyclic substance GO:0014070 55 29 1,000 5,486E-03 0,03814879 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 5,486E-03 0,03803885 ! regulation of T cell activation GO:0050863 158 94 2,000 5,649E-03 0,03905494 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 5,817E-03 0,04010244 ! forebrain development GO:0030900 188 95 2,000 5,817E-03 0,03998786 ! membrane docking GO:0022406 61 30 1,000 5,863E-03 0,04019145 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 5,863E-03 0,04007727 ! cofactor catabolic process GO:0051187 51 30 1,000 5,863E-03 0,03996374 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 5,863E-03 0,03985085 ! response to heat GO:0009408 50 30 1,000 5,863E-03 0,03973859 ! collagen metabolic process GO:0032963 45 31 1,000 6,252E-03 0,04225476 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 6,252E-03 0,0421364 ! iron ion homeostasis GO:0055072 54 31 1,000 6,252E-03 0,0420187 ! myeloid leukocyte activation GO:0002274 49 31 1,000 6,252E-03 0,04190166 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 6,252E-03 0,04178526 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 1,000 6,252E-03 0,04166952 ! interphase GO:0051325 213 98 2,000 6,339E-03 0,04213464 ! response to hydrogen peroxide GO:0042542 50 32 1,000 6,652E-03 0,04409295 ! proteoglycan metabolic process GO:0006029 63 32 1,000 6,652E-03 0,04397182 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 7,064E-03 0,04656472 ! cell fate specification GO:0001708 52 33 1,000 7,064E-03 0,04643749 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 7,487E-03 0,04908342 ! glial cell differentiation GO:0010001 63 34 1,000 7,487E-03 0,04895004 ! positive regulation of endocytosis GO:0045807 50 34 1,000 7,487E-03 0,04881738 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 7,487E-03 0,04868544 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 7,487E-03 0,04855422 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 7,487E-03 0,04842369 ! placenta development GO:0001890 53 34 1,000 7,487E-03 0,04829387 ! regulation of muscle development GO:0048634 70 35 1,000 7,921E-03 0,05095722 ! negative regulation of secretion GO:0051048 63 35 1,000 7,921E-03 0,05082134 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 7,921E-03 0,05068617 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 7,921E-03 0,05055173 ! calcium-mediated signaling GO:0019722 62 35 1,000 7,921E-03 0,05041799 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 8,366E-03 0,053111 ! regulation of proteolysis GO:0030162 72 36 1,000 8,366E-03 0,05297123 ! negative regulation of cell activation GO:0050866 65 36 1,000 8,366E-03 0,0528322 ! actomyosin structure organization GO:0031032 62 37 1,000 8,822E-03 0,05556701 ! negative regulation of DNA binding GO:0043392 68 37 1,000 8,822E-03 0,05542193 ! regulation of protein stability GO:0031647 73 37 1,000 8,822E-03 0,0552776 ! glycogen metabolic process GO:0005977 61 37 1,000 8,822E-03 0,05513402 ! pigment metabolic process GO:0042440 80 37 1,000 8,822E-03 0,05499119 ! carbohydrate homeostasis GO:0033500 53 38 1,000 9,289E-03 0,05775291 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 64 38 1,000 9,289E-03 0,05760406 ! glucan metabolic process GO:0044042 62 38 1,000 9,289E-03 0,05745598 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 1,000 9,767E-03 0,06025691 ! segmentation GO:0035282 67 39 1,000 9,767E-03 0,0601028 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 9,767E-03 0,05994947 ! Rho protein signal transduction GO:0007266 74 39 1,000 9,767E-03 0,05979693 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,01025596 0,06262902 ! negative regulation of binding GO:0051100 72 40 1,000 0,01025596 0,06247046 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,01025596 0,06231271 ! gliogenesis GO:0042063 88 41 1,000 0,01075523 0,06518158 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,01075523 0,06501781 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01126507 0,0679292 GO:0090047|positive regulation of transcription regulator activity, ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01178537 0,07088902 ! glucose transport GO:0015758 65 43 1,000 0,01178537 0,07071224 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,01178537 0,07053634 ! hexose transport GO:0008645 67 44 1,000 0,01231607 0,07352966 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 1,000 0,01231607 0,07334766 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,01231607 0,07316656 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,01285706 0,07619233 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,01285706 0,07600513 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 0,01285706 0,07581884 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,01285706 0,07563347 ! response to calcium ion GO:0051592 81 47 1,000 0,01396961 0,08197778 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,01396961 0,08177832 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,01396961 0,08157983 ! cellular component disassembly GO:0022411 86 48 1,000 0,014541 0,08471103 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,014541 0,08450642 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,014541 0,08430279 ! response to temperature stimulus GO:0009266 76 49 1,000 0,01512236 0,08746249 ! histone modification GO:0016570 91 50 1,000 0,01571359 0,09066405 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01571359 0,09044715 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,01571359 0,09023129 ! viral infectious cycle GO:0019058 99 51 1,000 0,01631463 0,09345952 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,01631463 0,09323752 ! excretion GO:0007588 83 51 1,000 0,01631463 0,09301658 ! regulation of cell shape GO:0008360 125 51 1,000 0,01631463 0,09279668 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01692538 0,09604355 ! membrane fusion GO:0006944 110 52 1,000 0,01692538 0,09581756 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01692538 0,09559264 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,01692538 0,09536877 ! regulation of translational initiation GO:0006446 82 53 1,000 0,01754577 0,09863344 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,01754577 0,09840353 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01817571 0,10169942 GO:0010863|positive regulation of phospholipase C activity, ! heterocycle catabolic process GO:0046700 85 54 1,000 0,01817571 0,10146345 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01881512 0,10478976 ! sulfur compound biosynthetic process GO:0044272 93 55 1,000 0,01881512 0,10454775 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01881512 0,10430686 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,01881512 0,10406707 ! heart morphogenesis GO:0003007 97 55 1,000 0,01881512 0,10382839 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,01881512 0,10359079 ! nuclear export GO:0051168 97 55 1,000 0,01881512 0,10335428 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01894821 0,10384826 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01894821 0,10361224 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01894821 0,10337729 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01894821 0,1031434 ! neuron fate determination GO:0048664 7 5 0,000 0,01894821 0,10291058 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01894821 0,10267879 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01894821 0,10244806 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01894821 0,10221835 ! polyol transport GO:0015791 12 5 0,000 0,01894821 0,10198968 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01894821 0,10176202 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01894821 0,10153538 ! response to superoxide GO:0000303 10 5 0,000 0,01894821 0,10130974 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01894821 0,10108511 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01894821 0,10086147 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01894821 0,10063882 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01894821 0,10041715 ! female meiosis GO:0007143 7 5 0,000 0,01894821 0,10019645 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01894821 0,09997672 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01894821 0,09975795 ! cobalt ion transport GO:0006824 11 5 0,000 0,01894821 0,09954014 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01894821 0,09932328 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01894821 0,09910736 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01894821 0,09889238 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01894821 0,09867832 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01894821 0,09846519 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01894821 0,09825298 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01894821 0,09804169 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01894821 0,0978313 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01894821 0,09762181 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01894821 0,09741322 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01894821 0,09720551 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01894821 0,09699869 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01894821 0,09679275 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01894821 0,09658768 ! negative chemotaxis GO:0050919 14 5 0,000 0,01894821 0,09638348 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01894821 0,09618014 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01894821 0,09597765 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01894821 0,09577602 ! behavioral response to pain GO:0048266 9 5 0,000 0,01894821 0,09557523 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01894821 0,09537528 ! Notch receptor processing GO:0007220 8 5 0,000 0,01894821 0,09517617 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01894821 0,09497789 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01894821 0,09478043 ! micturition GO:0060073 9 5 0,000 0,01894821 0,09458379 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01894821 0,09438796 ! copulation GO:0007620 9 5 0,000 0,01894821 0,09419294 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01894821 0,09399873 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01894821 0,09380532 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01894821 0,0936127 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01894821 0,09342087 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01894821 0,09322983 ! grooming behavior GO:0007625 6 5 0,000 0,01894821 0,09303956 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01894821 0,09285007 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01894821 0,09266135 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01894821 0,0924734 ! response to protozoan GO:0001562 10 5 0,000 0,01894821 0,0922862 ! lymph vessel development GO:0001945 10 5 0,000 0,01894821 0,09209977 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01894821 0,09191408 ! endochondral ossification GO:0001958 16 5 0,000 0,01894821 0,09172914 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01894821 0,09154495 ! parathyroid gland development GO:0060017 13 5 0,000 0,01894821 0,09136149 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01894821 0,09117877 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01894821 0,09099678 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01894821 0,09081551 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01894821 0,09063496 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01894821 0,09045513 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01894821 0,09027601 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01894821 0,0900976 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01894821 0,08991989 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01894821 0,08974288 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01894821 0,08956657 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01894821 0,08939095 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01894821 0,08921602 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01894821 0,08904177 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01894821 0,0888682 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01894821 0,0886953 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01894821 0,08852308 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01894821 0,08835152 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01894821 0,08818063 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01894821 0,0880104 ! histidine catabolic process GO:0006548 6 5 0,000 0,01894821 0,08784082 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01894821 0,08767189 ! microvillus organization GO:0032528 7 5 0,000 0,01894821 0,08750362 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01894821 0,08733599 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01894821 0,087169 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01894821 0,08700264 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01894821 0,08683692 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01894821 0,08667183 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01894821 0,08650737 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01894821 0,08634353 ! polyol catabolic process GO:0046174 7 5 0,000 0,01894821 0,08618031 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01894821 0,08601771 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01894821 0,08585572 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01894821 0,08569433 ! muscle cell migration GO:0014812 8 5 0,000 0,01894821 0,08553356 ! mitochondrial fission GO:0000266 8 5 0,000 0,01894821 0,08537338 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01894821 0,0852138 ! mRNA transcription GO:0009299 9 5 0,000 0,01894821 0,08505482 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01894821 0,08489643 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01894821 0,08473863 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01894821 0,08458142 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01894821 0,08442479 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01894821 0,08426873 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01894821 0,08411326 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01894821 0,08395835 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01894821 0,08380402 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01894821 0,08365025 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01894821 0,08349704 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01894821 0,0833444 ! forebrain neuron development GO:0021884 13 5 0,000 0,01894821 0,08319231 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01894821 0,08304077 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01894821 0,08288979 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01894821 0,08273936 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01894821 0,08258947 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01894821 0,08244012 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01894821 0,08229131 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01894821 0,08214304 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01894821 0,0819953 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01894821 0,08184809 ! basic amino acid transport GO:0015802 11 5 0,000 0,01894821 0,08170141 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01894821 0,08155525 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01894821 0,08140962 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01894821 0,0812645 ! depyrimidination GO:0045008 10 5 0,000 0,01894821 0,0811199 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01894821 0,08097582 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01894821 0,08083224 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01894821 0,08068918 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01894821 0,08054662 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01894821 0,08040456 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01894821 0,080263 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01894821 0,08012194 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01894821 0,07998138 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01894821 0,0798413 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01894821 0,07970172 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01894821 0,07956263 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01894821 0,07942402 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01894821 0,07928589 ! response to arsenic GO:0046685 10 5 0,000 0,01894821 0,07914824 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01894821 0,07901107 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01894821 0,07887437 GO:0002448|mast cell mediated immunity, ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01894821 0,07873814 ! response to cadmium ion GO:0046686 7 5 0,000 0,01894821 0,07860239 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01894821 0,0784671 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01894821 0,07833228 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01894821 0,07819792 ! decidualization GO:0046697 11 5 0,000 0,01894821 0,07806402 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01894821 0,07793057 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01894821 0,07779759 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01894821 0,07766505 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01894821 0,07753297 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01894821 0,07740133 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01894821 0,07727014 ! neural tube patterning GO:0021532 7 5 0,000 0,01894821 0,0771394 ! embryonic cleavage GO:0040016 6 5 0,000 0,01894821 0,0770091 ! peroxisome fission GO:0016559 5 5 0,000 0,01894821 0,07687923 ! histone demethylation GO:0016577 10 5 0,000 0,01894821 0,07674981 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01894821 0,07662081 ! mitotic recombination GO:0006312 9 5 0,000 0,01894821 0,07649226 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01894821 0,07636413 ! metaphase plate congression GO:0051310 7 5 0,000 0,01894821 0,07623643 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01894821 0,07610916 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01894821 0,07598231 ! enteric nervous system development GO:0048484 8 5 0,000 0,01894821 0,07585588 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01894821 0,07572988 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01894821 0,07560429 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01894821 0,07547911 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01894821 0,07535436 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01894821 0,07523001 ! plasminogen activation GO:0031639 5 5 0,000 0,01894821 0,07510607 ! B cell homeostasis GO:0001782 13 5 0,000 0,01894821 0,07498254 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01894821 0,07485942 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01894821 0,0747367 ! metaphase GO:0051323 8 5 0,000 0,01894821 0,07461438 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01894821 0,07449246 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01894821 0,07437094 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01894821 0,07424981 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01894821 0,07412908 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01894821 0,07400874 ! response to redox state GO:0051775 5 5 0,000 0,01894821 0,07388879 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01894821 0,07376923 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01894821 0,07365006 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01894821 0,07353127 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01894821 0,07341286 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01894821 0,07329483 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01894821 0,07317718 ! circadian behavior GO:0048512 13 5 0,000 0,01894821 0,07305991 ! striatum development GO:0021756 9 5 0,000 0,01894821 0,07294302 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01894821 0,07282649 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01894821 0,07271034 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01894821 0,07259456 ! glial cell migration GO:0008347 11 5 0,000 0,01894821 0,07247915 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01894821 0,0723641 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01894821 0,07224942 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01894821 0,0721351 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01894821 0,07202115 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01894821 0,07190755 ! neuroprotection GO:0043526 6 5 0,000 0,01894821 0,07179431 ! neural plate development GO:0001840 8 5 0,000 0,01894821 0,07168142 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01894821 0,07156889 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01894821 0,07145672 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01894821 0,07134489 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01894821 0,07123341 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01894821 0,07112229 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01894821 0,0710115 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01894821 0,07090107 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01894821 0,07079097 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01894821 0,07068122 ! spindle assembly GO:0051225 6 5 0,000 0,01894821 0,0705718 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01894821 0,07046273 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01894821 0,07035399 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01894821 0,07024559 ! drug metabolic process GO:0017144 6 5 0,000 0,01894821 0,07013752 ! stem cell division GO:0017145 11 5 0,000 0,01894821 0,07002978 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01894821 0,06992237 ! organ regeneration GO:0031100 7 5 0,000 0,01894821 0,06981529 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01894821 0,06970854 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01894821 0,06960211 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01894821 0,06949601 ! regulation of actin filament length GO:0030832 105 56 1,000 0,01946393 0,07127885 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01946393 0,07117052 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01946393 0,07106252 ! muscle fiber development GO:0048747 112 57 1,000 0,02012204 0,073354 ! lipid modification GO:0030258 97 57 1,000 0,02012204 0,07324302 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,02012204 0,07313238 ! maintenance of location GO:0051235 118 57 1,000 0,02012204 0,07302208 ! regulation of endocytosis GO:0030100 91 58 1,000 0,0207894 0,07533026 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,0207894 0,07521698 ! regulation of cellular component size GO:0032535 109 59 1,000 0,02146591 0,077548 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,02146591 0,07743174 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,02215149 0,07978516 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02269492 0,08162029 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02269492 0,08149846 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02269492 0,08137701 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02269492 0,08125591 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02269492 0,08113517 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02269492 0,08101479 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02269492 0,08089477 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02269492 0,08077511 ! sleep GO:0030431 13 6 0,000 0,02269492 0,08065579 ! response to oxygen radical GO:0000305 11 6 0,000 0,02269492 0,08053683 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02269492 0,08041822 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02269492 0,08029996 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02269492 0,08018204 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02269492 0,08006447 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02269492 0,07994725 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02269492 0,07983037 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02269492 0,07971383 ! forebrain regionalization GO:0021871 8 6 0,000 0,02269492 0,07959763 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02269492 0,07948176 ! male meiosis GO:0007140 7 6 0,000 0,02269492 0,07936624 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02269492 0,07925105 ! response to zinc ion GO:0010043 9 6 0,000 0,02269492 0,07913619 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02269492 0,07902167 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02269492 0,07890747 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02269492 0,07879361 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02269492 0,07868007 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02269492 0,07856686 ! malate metabolic process GO:0006108 11 6 0,000 0,02269492 0,07845398 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02269492 0,07834142 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02269492 0,07822919 ! protein refolding GO:0042026 15 6 0,000 0,02269492 0,07811727 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02269492 0,07800567 ! opsonization GO:0008228 8 6 0,000 0,02269492 0,0778944 ! mating behavior GO:0007617 7 6 0,000 0,02269492 0,07778343 ! neuron remodeling GO:0016322 15 6 0,000 0,02269492 0,07767279 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02269492 0,07756246 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02269492 0,07745244 ! equilibrioception GO:0050957 14 6 0,000 0,02269492 0,07734274 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02269492 0,07723334 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02269492 0,07712425 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02269492 0,07701547 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02269492 0,076907 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02269492 0,07679883 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02269492 0,07669097 ! toxin metabolic process GO:0009404 11 6 0,000 0,02269492 0,07658341 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02269492 0,07647615 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02269492 0,07636919 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02269492 0,07626253 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02269492 0,07615617 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02269492 0,0760501 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02269492 0,07594433 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02269492 0,07583885 ! thymic T cell selection GO:0045061 12 6 0,000 0,02269492 0,07573366 ! protein lipoylation GO:0009249 10 6 0,000 0,02269492 0,07562877 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02269492 0,07552416 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02269492 0,07541985 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02269492 0,07531582 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02269492 0,07521208 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02269492 0,07510863 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02269492 0,07500545 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02269492 0,07490257 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02269492 0,07479996 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02269492 0,07469763 ! hyperosmotic response GO:0006972 9 6 0,000 0,02269492 0,07459559 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02269492 0,07449382 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02269492 0,07439233 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02269492 0,07429112 ! urea metabolic process GO:0019627 7 6 0,000 0,02269492 0,07419018 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02269492 0,07408951 ! neutrophil activation GO:0042119 8 6 0,000 0,02269492 0,07398912 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02269492 0,073889 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02269492 0,07378915 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02269492 0,07368957 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02269492 0,07359026 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02269492 0,07349121 ! neuron apoptosis GO:0051402 9 6 0,000 0,02269492 0,07339243 ! nucleoside salvage GO:0043174 9 6 0,000 0,02269492 0,07329392 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02269492 0,07319567 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02269492 0,07309769 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02269492 0,07299996 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02269492 0,0729025 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02269492 0,07280529 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02269492 0,07270835 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02269492 0,07261166 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02269492 0,07251523 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02269492 0,07241906 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02269492 0,07232314 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02269492 0,07222748 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02269492 0,07213206 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02269492 0,0720369 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02269492 0,07194199 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02269492 0,07184733 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02269492 0,07175292 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02269492 0,07165875 ! neural nucleus development GO:0048857 14 6 0,000 0,02269492 0,07156484 ! response to UV-C GO:0010225 11 6 0,000 0,02269492 0,07147117 ! astrocyte development GO:0014002 15 6 0,000 0,02269492 0,07137774 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02269492 0,07128456 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02269492 0,07119162 ! interaction with symbiont GO:0051702 13 6 0,000 0,02269492 0,07109892 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02269492 0,07100646 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02269492 0,07091425 ! response to copper ion GO:0046688 10 6 0,000 0,02269492 0,07082227 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02269492 0,07073053 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02269492 0,07063903 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02269492 0,07054777 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02269492 0,07045674 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02269492 0,07036594 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02269492 0,07027538 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02269492 0,07018505 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02269492 0,07009496 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02269492 0,07000509 ! Schwann cell development GO:0014044 15 6 0,000 0,02269492 0,06991546 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02269492 0,06982605 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02269492 0,06973687 ! subpallium development GO:0021544 10 6 0,000 0,02269492 0,06964792 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02269492 0,0695592 ! histone ubiquitination GO:0016574 8 6 0,000 0,02269492 0,0694707 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02269492 0,06938243 ! G2 phase GO:0051319 16 6 0,000 0,02269492 0,06929438 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02269492 0,06920655 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02269492 0,06911895 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02269492 0,06903157 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02269492 0,06894441 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02269492 0,06885747 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02269492 0,06877074 ! receptor internalization GO:0031623 10 6 0,000 0,02269492 0,06868424 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02269492 0,06859795 ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02269492 0,06851188 ! protein deubiquitination GO:0016579 14 6 0,000 0,02269492 0,06842603 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02269492 0,06834039 ! protein destabilization GO:0031648 9 6 0,000 0,02269492 0,06825496 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02269492 0,06816975 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02269492 0,06808475 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02269492 0,06799996 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02269492 0,06791539 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02269492 0,06783102 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02269492 0,06774686 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02269492 0,06766291 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02269492 0,06757917 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02269492 0,06749564 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02269492 0,06741231 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02269492 0,06732919 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02269492 0,06724627 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02269492 0,06716356 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02269492 0,06708105 ! catecholamine transport GO:0051937 9 6 0,000 0,02269492 0,06699874 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02269492 0,06691663 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02269492 0,06683473 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02269492 0,06675302 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02269492 0,06667152 ! maternal placenta development GO:0001893 12 6 0,000 0,02269492 0,06659021 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02269492 0,0665091 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02269492 0,06642819 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02269492 0,06634747 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02269492 0,06626696 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02269492 0,06618663 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02269492 0,0661065 ! mesoderm development GO:0007498 119 61 1,000 0,02284608 0,06646633 ! gonad development GO:0008406 98 62 1,000 0,02354958 0,0684303 ! regulation of mitosis GO:0007088 105 63 1,000 0,02426193 0,07041521 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,02426193 0,07033037 ! germ cell development GO:0007281 118 65 1,000 0,02571286 0,07444662 ! tRNA transcription GO:0009304 14 7 0,000 0,02642744 0,07642359 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02642744 0,07633185 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02642744 0,07624032 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02642744 0,07614902 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02642744 0,07605793 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02642744 0,07596706 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02642744 0,07587641 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02642744 0,07578597 ! prostate gland development GO:0030850 13 7 0,000 0,02642744 0,07569575 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02642744 0,07560574 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02642744 0,07551595 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02642744 0,07542637 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02642744 0,075337 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02642744 0,07524784 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02642744 0,0751589 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02642744 0,07507016 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02642744 0,07498164 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02642744 0,07489332 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02642744 0,07480521 ! glycolipid transport GO:0046836 10 7 0,000 0,02642744 0,07471731 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02642744 0,07462961 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02642744 0,07454212 ! neuron adhesion GO:0007158 12 7 0,000 0,02642744 0,07445483 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02642744 0,07436775 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02642744 0,07428087 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02642744 0,0741942 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02642744 0,07410773 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02642744 0,07402145 ! mRNA stabilization GO:0048255 18 7 0,000 0,02642744 0,07393538 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02642744 0,07384951 ! fibril organization GO:0043206 16 7 0,000 0,02642744 0,07376384 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02642744 0,07367836 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02642744 0,07359309 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02642744 0,07350801 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02642744 0,07342313 ! lipoprotein transport GO:0042953 14 7 0,000 0,02642744 0,07333844 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02642744 0,07325395 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02642744 0,07316965 ! rhythmic behavior GO:0007622 15 7 0,000 0,02642744 0,07308555 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02642744 0,07300164 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02642744 0,07291792 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02642744 0,0728344 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02642744 0,07275106 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02642744 0,07266792 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02642744 0,07258496 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02642744 0,0725022 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02642744 0,07241962 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02642744 0,07233723 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02642744 0,07225503 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02642744 0,07217302 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02642744 0,07209119 ! spinal cord patterning GO:0021511 13 7 0,000 0,02642744 0,07200955 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02642744 0,07192809 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02642744 0,07184681 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02642744 0,07176572 ! adrenal gland development GO:0030325 17 7 0,000 0,02642744 0,07168481 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02642744 0,07160409 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02642744 0,07152354 ! ovulation GO:0030728 9 7 0,000 0,02642744 0,07144318 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02642744 0,07136299 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02642744 0,07128299 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02642744 0,07120317 ! microtubule nucleation GO:0007020 20 7 0,000 0,02642744 0,07112352 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02642744 0,07104405 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02642744 0,07096476 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02642744 0,07088565 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02642744 0,07080671 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02642744 0,07072795 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02642744 0,07064936 ! galactose metabolic process GO:0006012 13 7 0,000 0,02642744 0,07057095 ! response to dietary excess GO:0002021 8 7 0,000 0,02642744 0,07049271 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02642744 0,07041465 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02642744 0,07033676 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02642744 0,07025904 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02642744 0,07018149 ! organ growth GO:0035265 15 7 0,000 0,02642744 0,07010411 ! purine salvage GO:0043101 10 7 0,000 0,02642744 0,0700269 ! nucleoside transport GO:0015858 8 7 0,000 0,02642744 0,06994987 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02642744 0,069873 ! parturition GO:0007567 14 7 0,000 0,02642744 0,0697963 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02642744 0,06971977 ! rRNA modification GO:0000154 14 7 0,000 0,02642744 0,0696434 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02642744 0,06956721 ! spindle checkpoint GO:0031577 15 7 0,000 0,02642744 0,06949118 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02642744 0,06941531 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02642744 0,06933962 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02642744 0,06926408 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02642744 0,06918871 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02642744 0,06911351 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02642744 0,06903847 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02642744 0,06896359 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02642744 0,06888887 ! fibrinolysis GO:0042730 10 7 0,000 0,02642744 0,06881432 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02642744 0,06873992 ! eating behavior GO:0042755 7 7 0,000 0,02642744 0,06866569 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02642744 0,06859162 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02642744 0,0685177 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02642744 0,06844395 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02642744 0,06837035 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02642744 0,06829692 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02642744 0,06822364 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02642744 0,06815051 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02642744 0,06807755 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02642744 0,06800474 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02642744 0,06793208 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02642744 0,06785958 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02642744 0,06778724 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02642744 0,06771505 ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02642744 0,06764301 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02642744 0,06757112 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02642744 0,06749939 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02642744 0,06742781 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02642744 0,06735639 ! transcription termination GO:0006353 13 7 0,000 0,02642744 0,06728511 ! response to tumor cell GO:0002347 13 7 0,000 0,02642744 0,06721398 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02642744 0,06714301 ! anaphase GO:0051322 17 7 0,000 0,02642744 0,06707218 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02642744 0,0670015 ! axonal fasciculation GO:0007413 18 7 0,000 0,02642744 0,06693098 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02642744 0,0668606 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02642744 0,06679037 ! diuresis GO:0030146 12 7 0,000 0,02642744 0,06672028 GO:0030147|natriuresis, ! thiamin metabolic process GO:0006772 7 7 0,000 0,02642744 0,06665034 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02642744 0,06658055 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02642744 0,06651091 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02642744 0,06644141 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02642744 0,06637205 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02642744 0,06630284 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02642744 0,06623378 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02642744 0,06616486 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02642744 0,06609608 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02642744 0,06602744 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02642744 0,06595895 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02642744 0,0658906 ! lymph node development GO:0048535 10 7 0,000 0,02642744 0,06582239 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02642744 0,06575432 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02642744 0,06568639 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02642744 0,0656186 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02642744 0,06555096 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02642744 0,06548345 ! adult feeding behavior GO:0008343 9 7 0,000 0,02642744 0,06541608 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02642744 0,06534885 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02642744 0,06528175 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02642744 0,0652148 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02642744 0,06514798 ! retina homeostasis GO:0001895 12 7 0,000 0,02642744 0,0650813 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02642744 0,06501475 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02642744 0,06494834 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02642744 0,06488207 ! protein prenylation GO:0018342 18 7 0,000 0,02642744 0,06481593 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02642744 0,06474993 ! developmental maturation GO:0021700 116 66 1,000 0,02645129 0,06474241 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,02719825 0,06650305 ! activation of MAPK activity GO:0000187 115 67 1,000 0,02719825 0,06643553 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,02719825 0,06636815 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,02795369 0,06814242 ! regulation of lipase activity GO:0060191 130 68 1,000 0,02795369 0,06807345 ! negative regulation of cell size GO:0045792 134 69 1,000 0,02871751 0,06986282 ! urogenital system development GO:0001655 137 69 1,000 0,02871751 0,06979226 ! antigen processing and presentation GO:0019882 104 69 1,000 0,02871751 0,06972183 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03014584 0,07311581 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03014584 0,07304218 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03014584 0,0729687 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03014584 0,07289536 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03014584 0,07282217 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03014584 0,07274913 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03014584 0,07267624 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03014584 0,07260349 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03014584 0,07253088 ! meiotic prophase I GO:0007128 13 8 0,000 0,03014584 0,07245843 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03014584 0,07238611 ! oligopeptide transport GO:0006857 15 8 0,000 0,03014584 0,07231394 ! UTP metabolic process GO:0046051 8 8 0,000 0,03014584 0,07224192 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03014584 0,07217003 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03014584 0,07209829 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03014584 0,0720267 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03014584 0,07195524 ! succinate metabolic process GO:0006105 14 8 0,000 0,03014584 0,07188393 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03014584 0,07181276 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03014584 0,07174173 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03014584 0,07167083 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03014584 0,07160008 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03014584 0,07152947 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03014584 0,071459 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03014584 0,07138867 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03014584 0,07131847 ! reflex GO:0060004 16 8 0,000 0,03014584 0,07124841 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03014584 0,07117849 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03014584 0,07110871 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03014584 0,07103906 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03014584 0,07096955 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03014584 0,07090018 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03014584 0,07083094 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03014584 0,07076184 ! pigment granule organization GO:0048753 16 8 0,000 0,03014584 0,07069287 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03014584 0,07062404 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03014584 0,07055533 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03014584 0,07048677 ! histidine metabolic process GO:0006547 16 8 0,000 0,03014584 0,07041833 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03014584 0,07035003 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03014584 0,07028186 ! glycine catabolic process GO:0006546 13 8 0,000 0,03014584 0,07021383 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03014584 0,07014592 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03014584 0,07007815 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,03014584 0,07001051 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03014584 0,06994299 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03014584 0,06987561 ! melanin metabolic process GO:0006582 15 8 0,000 0,03014584 0,06980836 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03014584 0,06974123 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03014584 0,06967424 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03014584 0,06960737 ! macrophage activation GO:0042116 12 8 0,000 0,03014584 0,06954064 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03014584 0,06947403 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03014584 0,06940754 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03014584 0,06934119 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03014584 0,06927496 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03014584 0,06920886 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03014584 0,06914288 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03014584 0,06907703 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03014584 0,06901131 ! osteoblast development GO:0002076 16 8 0,000 0,03014584 0,06894571 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03014584 0,06888023 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03014584 0,06881488 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03014584 0,06874965 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03014584 0,06868455 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03014584 0,06861957 ! response to UV-B GO:0010224 16 8 0,000 0,03014584 0,06855471 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03014584 0,06848998 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03014584 0,06842536 ! intermediate filament organization GO:0045109 12 8 0,000 0,03014584 0,06836087 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03014584 0,0682965 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03014584 0,06823225 ! cellular extravasation GO:0045123 12 8 0,000 0,03014584 0,06816812 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03014584 0,06810412 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03014584 0,06804023 ! response to antibiotic GO:0046677 11 8 0,000 0,03014584 0,06797646 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03014584 0,06791281 ! DNA topological change GO:0006265 12 8 0,000 0,03014584 0,06784928 ! response to tropane GO:0014073 15 8 0,000 0,03014584 0,06778587 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03014584 0,06772258 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,03014584 0,06765941 ! melanosome transport GO:0032402 13 8 0,000 0,03014584 0,06759635 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03014584 0,06753341 ! mast cell activation GO:0045576 14 8 0,000 0,03014584 0,06747059 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03014584 0,06740789 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03014584 0,0673453 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03014584 0,06728282 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03014584 0,06722047 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03014584 0,06715823 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03014584 0,0670961 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03014584 0,06703409 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03014584 0,06697219 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03014584 0,06691041 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03014584 0,06684874 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03014584 0,06678719 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03014584 0,06672574 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03014584 0,06666442 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03014584 0,0666032 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03014584 0,0665421 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03014584 0,0664811 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03014584 0,06642022 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03014584 0,06635945 ! hormone catabolic process GO:0042447 17 8 0,000 0,03014584 0,0662988 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03014584 0,06623825 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03014584 0,06617781 ! ATP catabolic process GO:0006200 11 8 0,000 0,03014584 0,06611749 ! blastocyst growth GO:0001832 19 8 0,000 0,03014584 0,06605727 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03014584 0,06599716 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03014584 0,06593717 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03014584 0,06587728 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03014584 0,0658175 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03014584 0,06575783 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03014584 0,06569826 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03014584 0,06563881 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03014584 0,06557946 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03014584 0,06552022 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03014584 0,06546109 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03014584 0,06540206 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03014584 0,06534314 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03014584 0,06528432 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03014584 0,06522562 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03014584 0,06516701 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03014584 0,06510851 ! reproductive structure development GO:0048608 113 71 1,000 0,03027004 0,06531814 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0310586 0,06695968 ! carbohydrate transport GO:0008643 110 72 1,000 0,0310586 0,06689973 ! learning or memory GO:0007611 147 73 1,000 0,03185526 0,06855434 ! regulation of blood pressure GO:0008217 125 73 1,000 0,03185526 0,06849308 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,03265995 0,07016056 ! axon extension GO:0048675 15 9 0,000 0,03385015 0,07265251 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03385015 0,07258776 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03385015 0,07252312 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03385015 0,0724586 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03385015 0,07239419 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03385015 0,0723299 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03385015 0,07226572 ! phosphate transport GO:0006817 19 9 0,000 0,03385015 0,07220165 ! reproductive behavior GO:0019098 19 9 0,000 0,03385015 0,0721377 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03385015 0,07207386 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03385015 0,07201014 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03385015 0,07194653 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03385015 0,07188302 ! GTP metabolic process GO:0046039 9 9 0,000 0,03385015 0,07181964 ! RNA methylation GO:0001510 15 9 0,000 0,03385015 0,07175636 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03385015 0,07169319 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03385015 0,07163014 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03385015 0,07156719 ! artery development GO:0060840 24 9 0,000 0,03385015 0,07150436 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03385015 0,07144164 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03385015 0,07137902 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03385015 0,07131652 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03385015 0,07125413 ! chemosensory behavior GO:0007635 20 9 0,000 0,03385015 0,07119184 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03385015 0,07112967 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03385015 0,0710676 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03385015 0,07100564 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03385015 0,07094379 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03385015 0,07088204 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03385015 0,07082041 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03385015 0,07075888 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03385015 0,07069745 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03385015 0,07063614 ! protein targeting to ER GO:0045047 22 9 0,000 0,03385015 0,07057493 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03385015 0,07051382 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03385015 0,07045283 ! T cell selection GO:0045058 23 9 0,000 0,03385015 0,07039193 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03385015 0,07033115 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03385015 0,07027046 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03385015 0,07020989 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03385015 0,07014941 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03385015 0,07008904 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03385015 0,07002878 ! mannose metabolic process GO:0006013 13 9 0,000 0,03385015 0,06996861 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03385015 0,06990856 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03385015 0,0698486 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03385015 0,06978875 ! receptor clustering GO:0043113 18 9 0,000 0,03385015 0,069729 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03385015 0,06966935 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03385015 0,0696098 ! ruffle organization GO:0031529 15 9 0,000 0,03385015 0,06955036 ! retinol metabolic process GO:0042572 18 9 0,000 0,03385015 0,06949101 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03385015 0,06943177 ! behavioral fear response GO:0001662 22 9 0,000 0,03385015 0,06937263 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03385015 0,06931359 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03385015 0,06925465 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03385015 0,06919581 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03385015 0,06913707 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03385015 0,06907843 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03385015 0,06901989 ! segment specification GO:0007379 13 9 0,000 0,03385015 0,06896145 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03385015 0,0689031 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03385015 0,06884486 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03385015 0,06878671 ! response to amine stimulus GO:0014075 13 9 0,000 0,03385015 0,06872866 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03385015 0,06867071 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03385015 0,06861286 ! erythrocyte development GO:0048821 15 9 0,000 0,03385015 0,06855511 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03385015 0,06849745 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03385015 0,06843989 ! renal water homeostasis GO:0003091 14 9 0,000 0,03385015 0,06838242 ! postreplication repair GO:0006301 22 9 0,000 0,03385015 0,06832506 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03385015 0,06826778 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03385015 0,06821061 ! icosanoid secretion GO:0032309 15 9 0,000 0,03385015 0,06815353 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03385015 0,06809654 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03385015 0,06803965 ! regulation of cell division GO:0051302 15 9 0,000 0,03385015 0,06798286 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03385015 0,06792616 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03385015 0,06786956 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03385015 0,06781304 ! sterol catabolic process GO:0016127 11 9 0,000 0,03385015 0,06775663 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03385015 0,0677003 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03385015 0,06764408 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03385015 0,06758794 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03385015 0,0675319 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03385015 0,06747595 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03385015 0,06742009 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03385015 0,06736432 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03385015 0,06730865 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03385015 0,06725307 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03385015 0,06719758 ! purine base metabolic process GO:0006144 21 9 0,000 0,03385015 0,06714218 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03385015 0,06708688 ! pigment granule transport GO:0051904 17 9 0,000 0,03385015 0,06703166 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03385015 0,06697654 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,03385015 0,0669215 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03385015 0,06686656 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03385015 0,0668117 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03385015 0,06675694 ! mitochondrion localization GO:0051646 15 9 0,000 0,03385015 0,06670227 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,03429311 0,06751982 ! defense response to bacterium GO:0042742 89 76 1,000 0,03429311 0,06746461 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,03512145 0,06903774 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,03512145 0,06898139 ! blood coagulation GO:0007596 146 78 1,000 0,03595752 0,07056591 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,03595752 0,0705084 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,03680128 0,07210413 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,03680128 0,07204546 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03754044 0,07343277 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03754044 0,07337311 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03754044 0,07331356 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03754044 0,0732541 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03754044 0,07319474 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03754044 0,07313547 ! synapsis GO:0007129 13 10 0,000 0,03754044 0,0730763 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03754044 0,07301722 ! N-glycan processing GO:0006491 20 10 0,000 0,03754044 0,07295824 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03754044 0,07289936 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03754044 0,07284057 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03754044 0,07278187 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,03754044 0,07272327 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03754044 0,07266477 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03754044 0,07260635 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03754044 0,07254803 ! androgen metabolic process GO:0008209 17 10 0,000 0,03754044 0,07248981 ! phospholipid efflux GO:0033700 16 10 0,000 0,03754044 0,07243168 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03754044 0,07237364 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03754044 0,0723157 ! lung alveolus development GO:0048286 26 10 0,000 0,03754044 0,07225784 ! pathogenesis GO:0009405 13 10 0,000 0,03754044 0,07220008 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03754044 0,07214241 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03754044 0,07208484 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03754044 0,07202735 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03754044 0,07196996 ! endoderm development GO:0007492 16 10 0,000 0,03754044 0,07191266 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03754044 0,07185545 ! arginine catabolic process GO:0006527 13 10 0,000 0,03754044 0,07179833 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03754044 0,07174131 ! proline metabolic process GO:0006560 13 10 0,000 0,03754044 0,07168437 ! L-serine metabolic process GO:0006563 18 10 0,000 0,03754044 0,07162752 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03754044 0,07157076 ! V(D)J recombination GO:0033151 28 10 0,000 0,03754044 0,0715141 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03754044 0,07145752 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03754044 0,07140103 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03754044 0,07134463 ! B cell proliferation GO:0042100 18 10 0,000 0,03754044 0,07128832 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03754044 0,0712321 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03754044 0,07117597 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03754044 0,07111992 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03754044 0,07106397 ! epithelial cell development GO:0002064 20 10 0,000 0,03754044 0,0710081 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03754044 0,07095232 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03754044 0,07089663 ! macroautophagy GO:0016236 17 10 0,000 0,03754044 0,07084102 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03754044 0,0707855 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03754044 0,07073007 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03754044 0,07067473 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03754044 0,07061947 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,03754044 0,0705643 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03754044 0,07050921 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03754044 0,07045421 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03754044 0,0703993 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03754044 0,07034447 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03754044 0,07028973 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03754044 0,07023507 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03754044 0,0701805 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03754044 0,07012601 ! response to dsRNA GO:0043331 20 10 0,000 0,03754044 0,07007161 ! DNA ligation GO:0006266 19 10 0,000 0,03754044 0,07001729 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03754044 0,06996305 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03754044 0,0699089 ! melanosome localization GO:0032400 16 10 0,000 0,03754044 0,06985484 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03754044 0,06980085 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03754044 0,06974695 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03754044 0,06969314 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03754044 0,0696394 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03754044 0,06958575 ! mRNA cleavage GO:0006379 17 10 0,000 0,03754044 0,06953218 ! protein sumoylation GO:0016925 15 10 0,000 0,03754044 0,06947869 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03754044 0,06942529 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03754044 0,06937197 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03754044 0,06931873 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03754044 0,06926557 ! salivary gland development GO:0007431 27 10 0,000 0,03754044 0,06921249 ! prophase GO:0051324 15 10 0,000 0,03754044 0,0691595 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03754044 0,06910658 ! apical protein localization GO:0045176 15 10 0,000 0,03754044 0,06905375 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03754044 0,069001 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03754044 0,06894832 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03754044 0,06889573 ! midbrain development GO:0030901 13 10 0,000 0,03754044 0,06884322 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03754044 0,06879079 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03754044 0,06873843 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03754044 0,06868616 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03754044 0,06863397 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03754044 0,06858186 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03754044 0,06852982 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03754044 0,06847786 ! detection of calcium ion GO:0005513 23 10 0,000 0,03754044 0,06842599 ! oocyte development GO:0048599 17 10 0,000 0,03754044 0,06837419 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03754044 0,06832247 ! blastocyst formation GO:0001825 17 10 0,000 0,03754044 0,06827083 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03754044 0,06821926 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03754044 0,06816778 ! activation of innate immune response GO:0002218 12 10 0,000 0,03754044 0,06811637 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03754044 0,06806504 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03754044 0,06801378 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03754044 0,06796261 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03754044 0,06791151 ! response to metal ion GO:0010038 140 80 1,000 0,03765263 0,06806328 ! protein import into nucleus GO:0006606 158 80 1,000 0,03765263 0,06801218 ! inorganic anion transport GO:0015698 138 80 1,000 0,03765263 0,06796116 ! T cell activation GO:0042110 168 81 1,000 0,03851152 0,0694593 ! nuclear import GO:0051170 161 81 1,000 0,03851152 0,06940727 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,03851152 0,06935532 ! response to nutrient GO:0007584 125 82 1,000 0,03937787 0,07086249 ! hemostasis GO:0007599 158 84 1,000 0,04113269 0,07396506 ! negative regulation of transport GO:0051051 153 84 1,000 0,04113269 0,07390982 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,04113269 0,07385466 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04121676 0,07395042 ! respiratory burst GO:0045730 17 11 0,000 0,04121676 0,07389532 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04121676 0,0738403 ! neuron fate specification GO:0048665 17 11 0,000 0,04121676 0,07378536 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04121676 0,0737305 ! thyroid gland development GO:0030878 26 11 0,000 0,04121676 0,07367572 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04121676 0,07362102 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04121676 0,07356641 ! response to pain GO:0048265 24 11 0,000 0,04121676 0,07351188 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04121676 0,07345742 ! T cell proliferation GO:0042098 26 11 0,000 0,04121676 0,07340305 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04121676 0,07334876 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04121676 0,07329455 ! bone resorption GO:0045453 16 11 0,000 0,04121676 0,07324041 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04121676 0,07318636 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04121676 0,07313239 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04121676 0,0730785 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04121676 0,07302468 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04121676 0,07297095 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04121676 0,07291729 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04121676 0,07286372 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04121676 0,07281022 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04121676 0,0727568 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04121676 0,07270346 ! lipid digestion GO:0044241 18 11 0,000 0,04121676 0,0726502 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04121676 0,07259701 ! UV protection GO:0009650 19 11 0,000 0,04121676 0,07254391 ! adult heart development GO:0007512 14 11 0,000 0,04121676 0,07249088 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04121676 0,07243793 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04121676 0,07238505 ! temperature homeostasis GO:0001659 17 11 0,000 0,04121676 0,07233225 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04121676 0,07227953 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04121676 0,07222689 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04121676 0,07217432 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04121676 0,07212183 ! regulation of organ growth GO:0046620 13 11 0,000 0,04121676 0,07206942 ! pigment granule localization GO:0051875 20 11 0,000 0,04121676 0,07201708 ! vasoconstriction GO:0042310 18 11 0,000 0,04121676 0,07196482 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04121676 0,07191263 ! embryonic axis specification GO:0000578 18 11 0,000 0,04121676 0,07186052 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04121676 0,07180849 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04121676 0,07175653 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04121676 0,07170464 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04121676 0,07165283 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04121676 0,0716011 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04121676 0,07154944 ! zymogen activation GO:0031638 15 11 0,000 0,04121676 0,07149785 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04121676 0,07144634 ! nucleosome positioning GO:0016584 15 11 0,000 0,04121676 0,0713949 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04121676 0,07134354 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04121676 0,07129225 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04121676 0,07124103 ! acid secretion GO:0046717 18 11 0,000 0,04121676 0,07118989 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04121676 0,07113882 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04121676 0,07108783 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04121676 0,07103691 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04121676 0,07098606 ! oocyte differentiation GO:0009994 18 11 0,000 0,04121676 0,07093528 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04121676 0,07088457 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04121676 0,07083394 ! cholesterol efflux GO:0033344 19 11 0,000 0,04121676 0,07078338 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04121676 0,0707329 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04121676 0,07068248 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04121676 0,07063214 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04121676 0,07058186 ! embryonic gut development GO:0048566 15 11 0,000 0,04121676 0,07053166 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04121676 0,07048153 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04121676 0,07043148 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04121676 0,07038149 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04121676 0,07033157 ! defense response to fungus GO:0050832 13 11 0,000 0,04121676 0,07028173 ! lysogeny GO:0030069 21 11 0,000 0,04121676 0,07023195 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04121676 0,07018225 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04121676 0,07013262 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04121676 0,07008305 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04121676 0,07003356 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,04202102 0,07134974 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,04291655 0,07281892 ! tube morphogenesis GO:0035239 176 86 1,000 0,04291655 0,0727676 ! mitochondrion organization GO:0007005 148 86 1,000 0,04291655 0,07271636 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,04381921 0,07419353 ! protein localization in nucleus GO:0034504 176 87 1,000 0,04381921 0,07414136 ! regulation of neurological system process GO:0031644 148 88 1,000 0,04472892 0,0756274 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04487915 0,07582812 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04487915 0,07577491 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04487915 0,07572177 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,04487915 0,07566871 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04487915 0,07561572 ! cartilage condensation GO:0001502 20 12 0,000 0,04487915 0,0755628 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,04487915 0,07550996 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04487915 0,07545719 ! protein complex disassembly GO:0043241 27 12 0,000 0,04487915 0,0754045 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04487915 0,07535188 ! hippocampus development GO:0021766 26 12 0,000 0,04487915 0,07529933 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,04487915 0,07524686 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04487915 0,07519446 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04487915 0,07514213 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,04487915 0,07508988 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04487915 0,07503769 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04487915 0,07498559 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04487915 0,07493355 ! drug transport GO:0015893 16 12 0,000 0,04487915 0,07488158 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04487915 0,07482969 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04487915 0,07477787 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04487915 0,07472612 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04487915 0,07467444 ! focal adhesion formation GO:0048041 35 12 0,000 0,04487915 0,07462284 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04487915 0,0745713 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04487915 0,07451984 ! forebrain cell migration GO:0021885 21 12 0,000 0,04487915 0,07446844 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04487915 0,07441712 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04487915 0,07436587 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04487915 0,07431469 ! fear response GO:0042596 26 12 0,000 0,04487915 0,07426358 ! monoamine transport GO:0015844 18 12 0,000 0,04487915 0,07421254 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04487915 0,07416157 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04487915 0,07411067 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04487915 0,07405984 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04487915 0,07400908 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04487915 0,07395839 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04487915 0,07390776 ! protein homotetramerization GO:0051289 21 12 0,000 0,04487915 0,07385721 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04487915 0,07380673 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04487915 0,07375631 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04487915 0,07370597 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04487915 0,07365569 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04487915 0,07360548 ! cranial nerve development GO:0021545 20 12 0,000 0,04487915 0,07355534 ! fucose catabolic process GO:0019317 22 12 0,000 0,04487915 0,07350527 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04487915 0,07345527 ! histone methylation GO:0016571 26 12 0,000 0,04487915 0,07340533 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04487915 0,07335546 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04487915 0,07330566 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04487915 0,07325593 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04487915 0,07320627 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04487915 0,07315667 ! spleen development GO:0048536 22 12 0,000 0,04487915 0,07310714 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04487915 0,07305767 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04487915 0,07300828 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04487915 0,07295895 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04487915 0,07290968 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04487915 0,07286049 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04487915 0,07281136 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04487915 0,07276229 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04487915 0,07271329 ! response to cold GO:0009409 17 12 0,000 0,04487915 0,07266436 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04487915 0,0726155 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04487915 0,0725667 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,04564563 0,07375647 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,04564563 0,07370697 ! ossification GO:0001503 188 90 1,000 0,04656927 0,07514799 ! sex differentiation GO:0007548 145 90 1,000 0,04656927 0,07509763 ! bone development GO:0060348 189 91 1,000 0,04749977 0,07654684 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04852768 0,078151 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04852768 0,07809873 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04852768 0,07804652 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04852768 0,07799439 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04852768 0,07794232 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04852768 0,07789033 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04852768 0,0778384 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04852768 0,07778654 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04852768 0,07773475 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04852768 0,07768303 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04852768 0,07763138 ! methionine metabolic process GO:0006555 27 13 0,000 0,04852768 0,0775798 ! plasma membrane organization GO:0007009 24 13 0,000 0,04852768 0,07752829 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04852768 0,07747684 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04852768 0,07742546 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04852768 0,07737415 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04852768 0,07732291 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04852768 0,07727174 ! response to X-ray GO:0010165 25 13 0,000 0,04852768 0,07722063 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04852768 0,0771696 ! exocrine system development GO:0035272 32 13 0,000 0,04852768 0,07711862 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04852768 0,07706772 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04852768 0,07701689 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04852768 0,07696612 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04852768 0,07691541 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04852768 0,07686478 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04852768 0,07681421 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04852768 0,07676371 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04852768 0,07671327 ! regulation of cellular pH GO:0030641 22 13 0,000 0,04852768 0,0766629 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04852768 0,0766126 ! ribosome assembly GO:0042255 17 13 0,000 0,04852768 0,07656236 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04852768 0,07651219 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04852768 0,07646208 ! chromatin silencing GO:0006342 26 13 0,000 0,04852768 0,07641204 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04852768 0,07636207 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04852768 0,07631216 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04852768 0,07626231 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04852768 0,07621253 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04852768 0,07616282 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,04852768 0,07611317 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04852768 0,07606358 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04852768 0,07601406 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04852768 0,07596461 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04852768 0,07591521 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04852768 0,07586589 ! embryonic placenta development GO:0001892 23 13 0,000 0,04852768 0,07581662 ! insulin secretion GO:0030073 23 13 0,000 0,04852768 0,07576742 ! actin filament polymerization GO:0030041 24 13 0,000 0,04852768 0,07571829 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04852768 0,07566921 ! acrosome reaction GO:0007340 18 13 0,000 0,04852768 0,07562021 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,0493811 0,07690027 ! rRNA transcription GO:0009303 25 14 0,000 0,05216239 0,08117899 ! lactation GO:0007595 26 14 0,000 0,05216239 0,08112651 ! reproductive cellular process GO:0048610 20 14 0,000 0,05216239 0,0810741 ! tRNA modification GO:0006400 20 14 0,000 0,05216239 0,08102176 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05216239 0,08096949 ! regulation of S phase GO:0033261 23 14 0,000 0,05216239 0,08091729 ! water transport GO:0006833 21 14 0,000 0,05216239 0,08086515 GO:0042044|fluid transport, ! non-recombinational repair GO:0000726 25 14 0,000 0,05216239 0,08081308 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05216239 0,08076108 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05216239 0,08070914 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05216239 0,08065727 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,05216239 0,08060547 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05216239 0,08055373 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05216239 0,08050206 ! palate development GO:0060021 31 14 0,000 0,05216239 0,08045046 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05216239 0,08039892 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,05216239 0,08034745 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05216239 0,08029604 ! arginine metabolic process GO:0006525 17 14 0,000 0,05216239 0,0802447 ! regulation of heart rate GO:0002027 24 14 0,000 0,05216239 0,08019343 ! organic alcohol transport GO:0015850 29 14 0,000 0,05216239 0,08014222 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05216239 0,08009107 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,05216239 0,08003999 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,05216239 0,07998898 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05216239 0,07993803 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05216239 0,07988715 ! L-amino acid transport GO:0015807 30 14 0,000 0,05216239 0,07983633 ! bone mineralization GO:0030282 17 14 0,000 0,05216239 0,07978558 ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05216239 0,07973489 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,05216239 0,07968426 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05216239 0,0796337 ! cerebellum development GO:0021549 21 14 0,000 0,05216239 0,0795832 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05216239 0,07953277 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05216239 0,0794824 ! response to gamma radiation GO:0010332 28 14 0,000 0,05216239 0,0794321 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05216239 0,07938185 ! cofactor transport GO:0051181 26 14 0,000 0,05216239 0,07933168 ! NADP metabolic process GO:0006739 24 14 0,000 0,05216239 0,07928156 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,05216239 0,07923151 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05216239 0,07918152 ! intestinal absorption GO:0050892 25 14 0,000 0,05216239 0,0791316 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05216239 0,07908173 ! oxygen transport GO:0015671 21 14 0,000 0,05216239 0,07903193 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05216239 0,0789822 ! male genitalia development GO:0030539 24 14 0,000 0,05216239 0,07893252 ! regulation of RNA stability GO:0043487 32 14 0,000 0,05216239 0,07888291 ! regulation of axon extension GO:0030516 37 14 0,000 0,05216239 0,07883336 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,05216239 0,07878387 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05216239 0,07873445 ! positive regulation of immune response GO:0050778 156 96 1,000 0,05225295 0,0788217 ! protein ubiquitination GO:0016567 217 97 1,000 0,05322328 0,0802351 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05578334 0,08404177 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,05578334 0,08398918 ! superoxide anion generation GO:0042554 20 15 0,000 0,05578334 0,08393665 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,05578334 0,08388419 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05578334 0,0838318 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05578334 0,08377947 ! copper ion transport GO:0006825 20 15 0,000 0,05578334 0,0837272 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05578334 0,083675 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05578334 0,08362287 ! response to cAMP GO:0051591 22 15 0,000 0,05578334 0,0835708 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05578334 0,0835188 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05578334 0,08346686 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05578334 0,08341498 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05578334 0,08336317 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05578334 0,08331143 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05578334 0,08325974 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05578334 0,08320813 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05578334 0,08315657 ! pituitary gland development GO:0021983 29 15 0,000 0,05578334 0,08310508 ! vesicle coating GO:0006901 33 15 0,000 0,05578334 0,08305365 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05578334 0,08300229 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05578334 0,08295099 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,05578334 0,08289976 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,05578334 0,08284858 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05578334 0,08279747 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05578334 0,08274643 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05578334 0,08269544 ! histone deacetylation GO:0016575 20 15 0,000 0,05578334 0,08264452 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05578334 0,08259367 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05578334 0,08254287 ! muscle maintenance GO:0046716 26 15 0,000 0,05578334 0,08249214 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05578334 0,08244147 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05578334 0,08239086 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05578334 0,08234031 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05578334 0,08228983 ! cell killing GO:0001906 29 15 0,000 0,05578334 0,0822394 ! detection of bacterium GO:0016045 18 15 0,000 0,05578334 0,08218904 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,05578334 0,08213874 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05578334 0,08208851 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05578334 0,08203833 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05578334 0,08198821 ! peptide hormone processing GO:0016486 23 15 0,000 0,05578334 0,08193816 ! cell cycle arrest GO:0007050 213 100 1,000 0,05617253 0,08245949 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,05939057 0,08713031 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05939057 0,08707721 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05939057 0,08702418 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05939057 0,08697122 ! bone remodeling GO:0046849 27 16 0,000 0,05939057 0,08691831 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,05939057 0,08686548 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,05939057 0,0868127 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05939057 0,08675999 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,05939057 0,08670735 ! startle response GO:0001964 28 16 0,000 0,05939057 0,08665477 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05939057 0,08660225 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,05939057 0,08654979 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05939057 0,0864974 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05939057 0,08644507 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05939057 0,08639281 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05939057 0,08634061 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05939057 0,08628847 ! response to osmotic stress GO:0006970 25 16 0,000 0,05939057 0,0862364 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,05939057 0,08618438 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,05939057 0,08613243 ! fructose metabolic process GO:0006000 25 16 0,000 0,05939057 0,08608055 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05939057 0,08602872 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05939057 0,08597696 ! intermediate filament-based process GO:0045103 32 16 0,000 0,05939057 0,08592526 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,05939057 0,08587362 ! negative regulation of immune response GO:0050777 35 16 0,000 0,05939057 0,08582205 ! axon cargo transport GO:0008088 43 16 0,000 0,05939057 0,08577053 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05939057 0,08571908 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,05939057 0,08566769 ! DNA replication initiation GO:0006270 27 16 0,000 0,05939057 0,08561636 ! neuron recognition GO:0008038 35 16 0,000 0,05939057 0,08556509 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05939057 0,08551389 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05939057 0,08546274 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05939057 0,08541166 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,05939057 0,08536064 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05939057 0,08530968 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05939057 0,08525878 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05939057 0,08520794 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05939057 0,08515716 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05939057 0,08510644 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05939057 0,08505578 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,05939057 0,08500518 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,05939057 0,08495464 ! defense response to virus GO:0051607 37 16 0,000 0,05939057 0,08490416 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06298414 0,08998803 ! metencephalon development GO:0022037 30 17 0,000 0,06298414 0,08993462 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,06298414 0,08988128 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06298414 0,089828 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06298414 0,08977479 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06298414 0,08972163 ! endothelial cell migration GO:0043542 28 17 0,000 0,06298414 0,08966854 ! inositol metabolic process GO:0006020 28 17 0,000 0,06298414 0,08961552 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06298414 0,08956255 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06298414 0,08950965 ! glial cell development GO:0021782 27 17 0,000 0,06298414 0,08945681 ! limbic system development GO:0021761 36 17 0,000 0,06298414 0,08940404 ! adult walking behavior GO:0007628 33 17 0,000 0,06298414 0,08935132 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,06298414 0,08929867 ! heart looping GO:0001947 30 17 0,000 0,06298414 0,08924608 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06298414 0,08919355 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06298414 0,08914108 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06298414 0,08908868 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,06298414 0,08903633 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06298414 0,08898405 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06298414 0,08893183 ! glycine metabolic process GO:0006544 28 17 0,000 0,06298414 0,08887967 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06298414 0,08882757 ! NAD metabolic process GO:0019674 29 17 0,000 0,06298414 0,08877554 ! membrane budding GO:0006900 37 17 0,000 0,06298414 0,08872356 ! DNA integration GO:0015074 29 17 0,000 0,06298414 0,08867164 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,06298414 0,08861979 ! regulation of protein binding GO:0043393 33 17 0,000 0,06298414 0,088568 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06298414 0,08851626 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06298414 0,08846459 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06298414 0,08841298 ! genitalia development GO:0048806 30 17 0,000 0,06298414 0,08836142 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,06298414 0,08830993 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06298414 0,0882585 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,06298414 0,08820712 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,06298414 0,08815581 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06298414 0,08810456 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06298414 0,08805336 ! steroid catabolic process GO:0006706 31 17 0,000 0,06298414 0,08800223 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,06298414 0,08795115 ! gas transport GO:0015669 25 17 0,000 0,06298414 0,08790014 ! organic cation transport GO:0015695 31 17 0,000 0,06298414 0,08784918 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06298414 0,08779828 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,06298414 0,08774745 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06298414 0,08769667 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,06298414 0,08764595 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,06298414 0,08759528 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,0665641 0,09252064 ! neuron maturation GO:0042551 42 18 0,000 0,0665641 0,09246722 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,0665641 0,09241386 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,0665641 0,09236057 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,0665641 0,09230733 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,0665641 0,09225416 ! memory GO:0007613 31 18 0,000 0,0665641 0,09220105 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0665641 0,092148 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,0665641 0,09209501 ! patterning of blood vessels GO:0001569 39 18 0,000 0,0665641 0,09204208 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,0665641 0,09198922 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,0665641 0,09193641 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,0665641 0,09188366 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0665641 0,09183098 ! response to retinoic acid GO:0032526 26 18 0,000 0,0665641 0,09177835 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,0665641 0,09172579 ! response to fungus GO:0009620 21 18 0,000 0,0665641 0,09167328 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,0665641 0,09162084 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,0665641 0,09156845 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,0665641 0,09151613 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,0665641 0,09146386 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,0665641 0,09141166 ! vitamin transport GO:0051180 27 18 0,000 0,0665641 0,09135951 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,0665641 0,09130743 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,0665641 0,0912554 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,0665641 0,09120343 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,0665641 0,09115152 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,0665641 0,09109967 ! nerve development GO:0021675 28 18 0,000 0,0665641 0,09104788 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,0665641 0,09099615 ! protein secretion GO:0009306 39 19 0,000 0,0701305 0,09581714 ! positive regulation of translation GO:0045727 30 19 0,000 0,0701305 0,09576276 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0701305 0,09570845 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0701305 0,09565419 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0701305 0,09559999 ! skin development GO:0043588 36 19 0,000 0,0701305 0,09554586 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0701305 0,09549179 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0701305 0,09543778 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0701305 0,09538383 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0701305 0,09532994 ! cerebral cortex development GO:0021987 36 19 0,000 0,0701305 0,09527611 ! pigmentation during development GO:0048066 41 19 0,000 0,0701305 0,09522234 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,0701305 0,09516863 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,0701305 0,09511499 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0701305 0,0950614 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0701305 0,09500788 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0701305 0,09495441 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0701305 0,09490101 ! peptide cross-linking GO:0018149 37 19 0,000 0,0701305 0,09484766 ! heart process GO:0003015 30 19 0,000 0,0701305 0,09479438 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0701305 0,09474115 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0701305 0,09468798 ! cellular pigmentation GO:0033059 36 19 0,000 0,0701305 0,09463488 ! G1 phase GO:0051318 40 19 0,000 0,0701305 0,09458183 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0701305 0,09452885 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,0701305 0,09447592 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0701305 0,09442305 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0701305 0,09437024 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0701305 0,09431749 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0701305 0,0942648 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0701305 0,09421217 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0701305 0,09415959 ! cilium assembly GO:0042384 37 19 0,000 0,0701305 0,09410708 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0701305 0,09405462 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0736834 0,09876449 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,0736834 0,09870949 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0736834 0,09865456 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0736834 0,09859969 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0736834 0,09854489 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,0736834 0,09849014 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0736834 0,09843545 ! response to vitamin GO:0033273 31 20 0,000 0,0736834 0,09838083 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0736834 0,09832626 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0736834 0,09827176 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0736834 0,09821731 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0736834 0,09816293 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0736834 0,09810861 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0736834 0,09805434 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0736834 0,09800014 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0736834 0,09794599 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,0736834 0,09789191 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0736834 0,09783789 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0736834 0,09778392 ! body fluid secretion GO:0007589 31 20 0,000 0,0736834 0,09773002 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0736834 0,09767617 ! peptide secretion GO:0002790 35 20 0,000 0,0736834 0,09762238 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0736834 0,09756866 ! sensory perception of pain GO:0019233 30 20 0,000 0,0736834 0,09751499 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0736834 0,09746138 ! diencephalon development GO:0021536 34 20 0,000 0,0736834 0,09740783 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0736834 0,09735434 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0736834 0,09730091 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0736834 0,09724753 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0736834 0,09719422 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0736834 0,09714096 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0736834 0,09708776 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0736834 0,09703462 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0736834 0,09698154 ! regulation of glucose import GO:0046324 29 20 0,000 0,0736834 0,09692851 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0736834 0,09687555 ! actin filament-based movement GO:0030048 43 20 0,000 0,0736834 0,09682264 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,0736834 0,09676979 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0736834 0,09671699 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0736834 0,09666426 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,0736834 0,09661158 ! regulation of cell killing GO:0031341 42 21 0,000 0,07722283 0,10119724 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,07722283 0,10114215 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,07722283 0,10108712 ! hormone secretion GO:0046879 38 21 0,000 0,07722283 0,10103216 ! glycerol metabolic process GO:0006071 34 21 0,000 0,07722283 0,10097725 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,07722283 0,1009224 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,07722283 0,10086761 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,07722283 0,10081288 ! axis specification GO:0009798 38 21 0,000 0,07722283 0,10075821 ! ovarian follicle development GO:0001541 35 21 0,000 0,07722283 0,1007036 ! smooth muscle contraction GO:0006939 46 21 0,000 0,07722283 0,10064904 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,07722283 0,10059455 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,07722283 0,10054012 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,07722283 0,10048574 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,07722283 0,10043142 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,07722283 0,10037717 ! cytolysis GO:0019835 24 21 0,000 0,07722283 0,10032297 ! vasodilation GO:0042311 39 21 0,000 0,07722283 0,10026883 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,07722283 0,10021474 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,07722283 0,10016072 ! oogenesis GO:0048477 36 21 0,000 0,07722283 0,10010675 ! DNA modification GO:0006304 34 21 0,000 0,07722283 0,10005285 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,07722283 0,099999 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,07722283 0,0999452 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,07722283 0,09989147 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,07722283 0,09983779 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,07722283 0,09978418 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,07722283 0,09973061 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,07722283 0,09967711 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,07722283 0,09962366 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,07722283 0,09957028 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,07722283 0,09951694 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,07722283 0,09946367 ! sperm-egg recognition GO:0035036 21 21 0,000 0,07722283 0,09941045 ! gut development GO:0048565 39 21 0,000 0,07722283 0,09935729 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08074886 0,10383846 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08074886 0,10378299 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,08074886 0,10372758 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,08074886 0,10367223 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,08074886 0,10361694 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08074886 0,10356171 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,08074886 0,10350653 ! keratinization GO:0031424 28 22 0,000 0,08074886 0,10345142 ! sensory perception of taste GO:0050909 28 22 0,000 0,08074886 0,10339636 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,08074886 0,10334136 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08074886 0,10328642 ! vacuolar transport GO:0007034 36 22 0,000 0,08074886 0,10323154 ! lysosome organization GO:0007040 41 22 0,000 0,08074886 0,10317672 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08074886 0,10312195 ! fucose metabolic process GO:0006004 39 22 0,000 0,08074886 0,10306725 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08074886 0,1030126 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,08074886 0,10295801 ! ureteric bud development GO:0001657 43 22 0,000 0,08074886 0,10290347 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,08074886 0,102849 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,08074886 0,10279458 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,08074886 0,10274022 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,08074886 0,10268592 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08074886 0,10263167 ! sarcomere organization GO:0045214 30 22 0,000 0,08074886 0,10257749 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,08074886 0,10252336 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,08074886 0,10246928 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08074886 0,10241527 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,08074886 0,10236131 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,08074886 0,1023074 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,08426153 0,10670171 ! gluconeogenesis GO:0006094 33 23 0,000 0,08426153 0,10664558 ! viral genome replication GO:0019079 41 23 0,000 0,08426153 0,10658951 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,08426153 0,1065335 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,08426153 0,10647755 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,08426153 0,10642165 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,08426153 0,10636582 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,08426153 0,10631004 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,08426153 0,10625432 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,08426153 0,10619866 ! response to ethanol GO:0045471 46 23 0,000 0,08426153 0,10614306 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,08426153 0,10608752 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,08426153 0,10603203 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,08426153 0,10597661 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,08426153 0,10592124 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,08426153 0,10586593 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,08426153 0,10581067 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,08426153 0,10575548 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,08426153 0,10570034 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,08426153 0,10564526 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,08426153 0,10559023 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,08426153 0,10553527 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,08426153 0,10548036 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,08426153 0,10542551 ! fatty acid transport GO:0015908 44 23 0,000 0,08426153 0,10537071 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,08426153 0,10531597 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,08426153 0,10526129 ! hormone transport GO:0009914 40 23 0,000 0,08426153 0,10520667 ! cell-cell recognition GO:0009988 25 23 0,000 0,08426153 0,1051521 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,08426153 0,10509759 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,08426153 0,10504313 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,08426153 0,10498874 GO:0006099|tricarboxylic acid cycle, ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,0877609 0,1092923 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,0877609 0,10923576 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,0877609 0,10917928 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,0877609 0,10912286 ! spinal cord development GO:0021510 47 24 0,000 0,0877609 0,10906649 ! vacuole organization GO:0007033 43 24 0,000 0,0877609 0,10901018 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,0877609 0,10895393 ! digestive system process GO:0022600 39 24 0,000 0,0877609 0,10889774 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,0877609 0,10884161 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,0877609 0,10878554 ! regulation of behavior GO:0050795 43 24 0,000 0,0877609 0,10872952 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,0877609 0,10867356 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,0877609 0,10861766 ! pallium development GO:0021543 49 24 0,000 0,0877609 0,10856181 ! pentose metabolic process GO:0019321 35 24 0,000 0,0877609 0,10850603 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,0877609 0,1084503 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,0877609 0,10839462 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,0877609 0,10833901 ! alditol metabolic process GO:0019400 38 24 0,000 0,0877609 0,10828345 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,0877609 0,10822795 ! regulation of amine transport GO:0051952 40 24 0,000 0,0877609 0,1081725 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,09124701 0,11241183 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,09124701 0,1123543 ! myelination GO:0042552 45 25 0,000 0,09124701 0,11229683 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,09124701 0,11223942 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,09124701 0,11218207 ! phototransduction GO:0007602 33 25 0,000 0,09124701 0,11212477 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,09124701 0,11206754 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,09124701 0,11201036 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,09124701 0,11195324 ! receptor metabolic process GO:0043112 46 25 0,000 0,09124701 0,11189618 ! chromosome condensation GO:0030261 45 25 0,000 0,09124701 0,11183918 ! response to starvation GO:0042594 42 25 0,000 0,09124701 0,11178223 ! osteoblast differentiation GO:0001649 60 25 0,000 0,09124701 0,11172535 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,09124701 0,11166852 ! neural crest cell development GO:0014032 54 25 0,000 0,09124701 0,11161175 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,09124701 0,11155503 ! negative regulation of cell development GO:0010721 73 25 0,000 0,09124701 0,11149838 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,09124701 0,11144178 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,09124701 0,11138524 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,09124701 0,11132876 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,09124701 0,11127233 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,09124701 0,11121596 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,09124701 0,11115965 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,09124701 0,11110339 ! telomere organization GO:0032200 43 25 0,000 0,09124701 0,1110472 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,09124701 0,11099105 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,09124701 0,11093497 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,09471991 0,11509905 ! embryonic pattern specification GO:0009880 44 26 0,000 0,09471991 0,11504094 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,09471991 0,1149829 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,09471991 0,11492492 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,09471991 0,11486699 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,09471991 0,11480912 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,09471991 0,11475131 ! tube lumen formation GO:0035148 50 26 0,000 0,09471991 0,11469356 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,09471991 0,11463587 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,09471991 0,11457823 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,09471991 0,11452066 GO:0051297|centrosome organization, ! response to estradiol stimulus GO:0032355 40 26 0,000 0,09471991 0,11446314 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,09471991 0,11440568 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,09471991 0,11434827 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,09471991 0,11429093 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,09471991 0,11423364 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,09471991 0,11417641 ! blastocyst development GO:0001824 49 26 0,000 0,09471991 0,11411923 ! leukocyte proliferation GO:0070661 52 26 0,000 0,09471991 0,11406212 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,09471991 0,11400506 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,09471991 0,11394805 ! neuron fate commitment GO:0048663 48 27 0,000 0,09817966 0,1180511 ! iron ion transport GO:0006826 59 27 0,000 0,09817966 0,11799214 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,09817966 0,11793323 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,09817966 0,11787438 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,09817966 0,11781559 ! fat cell differentiation GO:0045444 50 27 0,000 0,09817966 0,11775686 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,09817966 0,11769819 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,09817966 0,11763957 ! autophagy GO:0006914 41 27 0,000 0,09817966 0,11758101 ! male gonad development GO:0008584 44 27 0,000 0,09817966 0,11752252 ! response to toxin GO:0009636 47 27 0,000 0,09817966 0,11746408 ! primary neural tube formation GO:0014020 51 27 0,000 0,09817966 0,11740569 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,09817966 0,11734737 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,09817966 0,11728911 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,09817966 0,1172309 ! glutathione metabolic process GO:0006749 39 27 0,000 0,09817966 0,11717275 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,09817966 0,11711465 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,09817966 0,11705662 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,09817966 0,11699864 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,1016263 0,12104597 ! circadian rhythm GO:0007623 50 28 0,000 0,1016263 0,12098608 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,1016263 0,12092625 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,1016263 0,12086647 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,1016263 0,12080675 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,1016263 0,1207471 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,1016263 0,1206875 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,1016263 0,12062796 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,1016263 0,12056848 ! synaptogenesis GO:0007416 42 28 0,000 0,1016263 0,12050905 ! lipid oxidation GO:0034440 43 28 0,000 0,1016263 0,12044969 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,1016263 0,12039038 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,1016263 0,12033114 ! translational initiation GO:0006413 65 29 0,000 0,10505988 0,12433549 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,10505988 0,12427437 ! regulation of pH GO:0006885 43 29 0,000 0,10505988 0,1242133 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,10505988 0,12415229 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,10505988 0,12409134 ! catechol metabolic process GO:0009712 54 29 0,000 0,10505988 0,12403045 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,10505988 0,12396962 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,10505988 0,12390885 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,10505988 0,12384814 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,10505988 0,12378749 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 60 29 0,000 0,10505988 0,1237269 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,10505988 0,12366637 ! detection of light stimulus GO:0009583 38 29 0,000 0,10505988 0,1236059 ! tissue homeostasis GO:0001894 48 29 0,000 0,10505988 0,12354548 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,10848045 0,1275056 ! zinc ion transport GO:0006829 45 30 0,000 0,10848045 0,12744334 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,10848045 0,12738114 ! cell junction assembly GO:0034329 78 30 0,000 0,10848045 0,127319 ! regulation of innate immune response GO:0045088 51 30 0,000 0,10848045 0,12725692 ! acute-phase response GO:0006953 49 30 0,000 0,10848045 0,12719491 ! myofibril assembly GO:0030239 47 30 0,000 0,10848045 0,12713295 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,10848045 0,12707106 ! phospholipid transport GO:0015914 51 30 0,000 0,10848045 0,12700922 ! ensheathment of neurons GO:0007272 57 30 0,000 0,10848045 0,12694745 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,10848045 0,12688573 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 48 30 0,000 0,10848045 0,12682408 ! eye morphogenesis GO:0048592 60 30 0,000 0,10848045 0,12676248 ! regulation of B cell activation GO:0050864 50 30 0,000 0,10848045 0,12670095 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,11188806 0,1306175 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,11188806 0,13055415 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,11188806 0,13049087 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,11188806 0,13042765 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,11188806 0,13036449 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,11188806 0,13030139 ! ovulation cycle process GO:0022602 49 31 0,000 0,11188806 0,13023835 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,11188806 0,13017537 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,11188806 0,13011245 ! peptide transport GO:0015833 55 31 0,000 0,11188806 0,13004959 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,11188806 0,1299868 ! mesoderm formation GO:0001707 69 31 0,000 0,11188806 0,12992406 ! natural killer cell activation GO:0030101 45 31 0,000 0,11188806 0,12986139 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,11188806 0,12979878 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,11188806 0,12973622 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,11528275 0,13360805 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,11528275 0,13354372 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,11528275 0,13347945 ! spliceosome assembly GO:0000245 67 32 0,000 0,11528275 0,13341525 ! spindle organization GO:0007051 46 32 0,000 0,11528275 0,13335111 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,11528275 0,13328703 ! metanephros development GO:0001656 74 32 0,000 0,11528275 0,13322301 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,11528275 0,13315905 ! response to ionizing radiation GO:0010212 65 32 0,000 0,11528275 0,13309516 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,11528275 0,13303132 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,11528275 0,13296755 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,11528275 0,13290384 ! muscle cell development GO:0055001 49 32 0,000 0,11528275 0,13284018 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,11528275 0,13277659 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,11528275 0,13271306 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,11528275 0,1326496 ! ovulation cycle GO:0042698 51 32 0,000 0,11528275 0,13258619 ! peripheral nervous system development GO:0007422 64 32 0,000 0,11528275 0,13252284 ! BMP signaling pathway GO:0030509 64 32 0,000 0,11528275 0,13245955 ! hindbrain development GO:0030902 61 32 0,000 0,11528275 0,13239633 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,11528275 0,13233316 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,11528275 0,13227005 ! gene silencing GO:0016458 65 32 0,000 0,11528275 0,13220701 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,11866459 0,13602048 ! post-embryonic development GO:0009791 69 33 0,000 0,11866459 0,13595571 ! protein targeting to membrane GO:0006612 68 33 0,000 0,11866459 0,135891 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,11866459 0,13582635 ! ceramide metabolic process GO:0006672 64 33 0,000 0,11866459 0,13576177 ! formation of primary germ layer GO:0001704 72 33 0,000 0,11866459 0,13569724 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,11866459 0,13563278 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,11866459 0,13556837 ! adult locomotory behavior GO:0008344 59 33 0,000 0,11866459 0,13550403 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,11866459 0,13543975 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,11866459 0,13537553 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,12203361 0,13915301 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,12203361 0,13908709 ! mismatch repair GO:0006298 46 34 0,000 0,12203361 0,13902124 ! spermatid development GO:0007286 63 34 0,000 0,12203361 0,13895545 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,12203361 0,13888971 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,12203361 0,13882405 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,12538986 0,14257467 ! odontogenesis GO:0042476 66 35 0,000 0,12538986 0,14250732 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,12538986 0,14244004 ! female gonad development GO:0008585 58 35 0,000 0,12538986 0,14237282 ! telencephalon development GO:0021537 68 35 0,000 0,12538986 0,14230566 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,12538986 0,14223857 ! cytokine production GO:0001816 59 35 0,000 0,12538986 0,14217154 ! neural tube formation GO:0001841 67 35 0,000 0,12538986 0,14210457 ! vesicle localization GO:0051648 64 35 0,000 0,12538986 0,14203766 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,12873339 0,14575649 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,12873339 0,14568793 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,12873339 0,14561944 ! cell junction organization GO:0034330 86 36 0,000 0,12873339 0,14555101 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,12873339 0,14548264 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,12873339 0,14541434 ! positive regulation of cell development GO:0010720 80 36 0,000 0,12873339 0,1453461 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,12873339 0,14527793 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,12873339 0,14520982 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,12873339 0,14514177 ! aerobic respiration GO:0009060 55 36 0,000 0,12873339 0,14507379 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,12873339 0,14500587 ! embryonic organ development GO:0048568 57 36 0,000 0,12873339 0,14493802 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,12873339 0,14487023 ! RNA export from nucleus GO:0006405 56 37 0,000 0,13206425 0,14854913 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,13206425 0,14847972 ! meiosis I GO:0007127 65 37 0,000 0,13206425 0,14841037 ! sister chromatid segregation GO:0000819 58 37 0,000 0,13206425 0,14834108 ! organic anion transport GO:0015711 68 37 0,000 0,13206425 0,14827186 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,13206425 0,1482027 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,13206425 0,14813361 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,13206425 0,14806458 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,13206425 0,14799562 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,13538249 0,15164352 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,13538249 0,15157295 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,13538249 0,15150245 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,13538249 0,15143202 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,13538249 0,15136165 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,13538249 0,15129135 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,13538249 0,15122111 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,13538249 0,15115094 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,13538249 0,15108083 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,13538249 0,15101079 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,13538249 0,15094081 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,13538249 0,1508709 ! mRNA catabolic process GO:0006402 71 39 0,000 0,13868815 0,15448319 ! ear morphogenesis GO:0042471 60 39 0,000 0,13868815 0,15441171 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,13868815 0,15434029 ! ion transmembrane transport GO:0034220 66 39 0,000 0,13868815 0,15426893 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,13868815 0,15419764 ! RNA modification GO:0009451 57 39 0,000 0,13868815 0,15412642 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,13868815 0,15405526 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,14198129 0,15764051 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,14198129 0,15756779 ! feeding behavior GO:0007631 59 40 0,000 0,14198129 0,15749515 ! mesenchymal cell development GO:0014031 87 40 0,000 0,14198129 0,15742257 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,14198129 0,15735006 ! maintenance of protein location GO:0045185 91 40 0,000 0,14198129 0,15727761 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,14526194 0,16083766 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,14526194 0,16076367 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,14526194 0,16068976 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,14526194 0,16061591 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,14526194 0,16054213 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,14526194 0,16046842 ! T cell differentiation GO:0030217 81 41 0,000 0,14526194 0,16039478 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,14526194 0,1603212 ! female gamete generation GO:0007292 61 41 0,000 0,14526194 0,1602477 ! polyol metabolic process GO:0019751 66 41 0,000 0,14526194 0,16017426 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,14526194 0,16010088 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,14853016 0,163628 ! regulation of tube size GO:0035150 71 42 0,000 0,14853016 0,16355311 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,14853016 0,1634783 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,14853016 0,16340355 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,14853016 0,16332886 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,14853016 0,16325425 ! neuron migration GO:0001764 79 42 0,000 0,14853016 0,16317971 ! regulation of protein secretion GO:0050708 71 42 0,000 0,14853016 0,16310523 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,14853016 0,16303082 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,15178598 0,16652853 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,15178598 0,16645263 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,15178598 0,1663768 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,15178598 0,16630104 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,15178598 0,16622534 ! neural tube development GO:0021915 77 43 0,000 0,15178598 0,16614972 ! striated muscle contraction GO:0006941 77 43 0,000 0,15178598 0,16607416 ! phagocytosis GO:0006909 90 43 0,000 0,15178598 0,16599867 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,15178598 0,16592325 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,15502947 0,16939187 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,15502947 0,16931498 ! double-strand break repair GO:0006302 81 44 0,000 0,15502947 0,16923816 ! biopolymer methylation GO:0043414 84 44 0,000 0,15502947 0,16916141 ! B cell differentiation GO:0030183 107 44 0,000 0,15502947 0,16908473 ! maintenance of location in cell GO:0051651 97 44 0,000 0,15502947 0,16900811 ! glycolysis GO:0006096 65 45 0,000 0,15826066 0,17245251 ! leukocyte migration GO:0050900 68 45 0,000 0,15826066 0,17237445 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,15826066 0,17229645 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,15826066 0,17221852 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,15826066 0,17214067 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,15826066 0,17206288 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,1614796 0,17548325 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,1614796 0,17540403 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,1614796 0,17532488 ! pigmentation GO:0043473 100 46 0,000 0,1614796 0,17524579 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,1614796 0,17516678 ! positive regulation of defense response GO:0031349 76 47 0,000 0,16468634 0,17856482 ! endosome transport GO:0016197 108 47 0,000 0,16468634 0,17848439 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,16468634 0,17840403 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,16468634 0,17832374 ! JNK cascade GO:0007254 91 47 0,000 0,16468634 0,17824352 ! methylation GO:0032259 90 47 0,000 0,16468634 0,17816337 ! mitochondrial transport GO:0006839 82 48 0,000 0,16788092 0,18153775 ! Notch signaling pathway GO:0007219 96 48 0,000 0,16788092 0,1814562 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,16788092 0,18137472 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,16788092 0,18129331 ! activation of caspase activity GO:0006919 84 48 0,000 0,16788092 0,18121198 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,16788092 0,18113072 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,16788092 0,18104953 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,16788092 0,18096842 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,17106339 0,1843164 ! regulation of action potential GO:0001508 95 49 0,000 0,17106339 0,1842339 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,17106339 0,18415147 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,17106339 0,18406911 ! regulation of ion transport GO:0043269 77 49 0,000 0,17106339 0,18398682 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,17106339 0,18390461 ! peptide metabolic process GO:0006518 76 49 0,000 0,17106339 0,18382248 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,17106339 0,18374041 ! endocrine system development GO:0035270 104 49 0,000 0,17106339 0,18365842 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,17106339 0,18357651 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,17106339 0,18349466 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,17106339 0,18341289 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,17106339 0,18333119 ! neuromuscular process GO:0050905 99 50 0,000 0,1742338 0,18664582 ! regulation of ossification GO:0030278 117 50 0,000 0,1742338 0,18656276 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,1742338 0,18647977 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,17739218 0,18977572 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,17739218 0,18969137 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,17739218 0,1896071 ! chromatin remodeling GO:0006338 109 51 0,000 0,17739218 0,18952291 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,17739218 0,18943879 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,17739218 0,18935474 ! amino acid activation GO:0043038 92 52 0,000 0,18053859 0,19262787 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,18053859 0,19254249 ! synapse organization GO:0050808 85 52 0,000 0,18053859 0,19245718 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,18367307 0,19571187 ! RNA catabolic process GO:0006401 93 53 0,000 0,18367307 0,19562523 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,18367307 0,19553867 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,18367307 0,19545219 ! cell maturation GO:0048469 100 53 0,000 0,18367307 0,19536578 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,18679566 0,19859936 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,18679566 0,19851164 ! cell recognition GO:0008037 85 54 0,000 0,18679566 0,198424 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,18679566 0,19833643 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,18679566 0,19824894 ! chloride transport GO:0006821 90 55 0,000 0,18990641 0,20146156 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,18990641 0,20137277 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,18990641 0,20128406 ! gastrulation GO:0007369 112 55 0,000 0,18990641 0,20119543 ! RNA elongation GO:0006354 79 55 0,000 0,18990641 0,20110688 ! sensory perception of smell GO:0007608 80 56 0,000 0,19300536 0,20429868 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,19300536 0,20420884 ! proton transport GO:0015992 94 56 0,000 0,19300536 0,20411908 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,19609257 0,20729293 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,19609257 0,20720189 ! hydrogen transport GO:0006818 97 58 0,000 0,19916806 0,21035924 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,19916806 0,21026694 ! adult behavior GO:0030534 99 58 0,000 0,19916806 0,21017472 ! positive regulation of secretion GO:0051047 95 59 0,000 0,20223189 0,2133143 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,20223189 0,21322083 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,20223189 0,21312743 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,20223189 0,21303412 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,20223189 0,21294089 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,2052841 0,21606017 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,2052841 0,2159657 ! regulation of heart contraction GO:0008016 110 60 0,000 0,2052841 0,2158713 ! camera-type eye development GO:0043010 116 60 0,000 0,2052841 0,215777 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,2052841 0,21568277 ! kidney development GO:0001822 122 60 0,000 0,2052841 0,21558863 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,20832473 0,21868644 ! tRNA processing GO:0008033 89 61 0,000 0,20832473 0,21859106 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,20832473 0,21849578 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,21135383 0,22157618 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,21135383 0,22147967 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,21437145 0,22454406 ! detection of external stimulus GO:0009581 91 63 0,000 0,21437145 0,22444634 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,21437145 0,22434872 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,21737761 0,22739588 ! cell redox homeostasis GO:0045454 102 64 0,000 0,21737761 0,22729706 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,21737761 0,22719832 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,21737761 0,22709967 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,21737761 0,2270011 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,22037237 0,2300286 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,22037237 0,22992885 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,22335577 0,23294061 ! actin filament organization GO:0007015 148 66 0,000 0,22335577 0,23283969 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,22335577 0,23273884 ! extracellular matrix organization GO:0030198 133 66 0,000 0,22335577 0,23263809 ! secondary metabolic process GO:0019748 116 66 0,000 0,22335577 0,23253743 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,22632786 0,23552977 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,22632786 0,23542794 ! chromosome segregation GO:0007059 113 67 0,000 0,22632786 0,2353262 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,22632786 0,23522455 ! hexose catabolic process GO:0019320 104 67 0,000 0,22632786 0,23512298 ! adaptive immune response GO:0002250 119 67 0,000 0,22632786 0,2350215 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,22632786 0,23492011 ! amino acid transport GO:0006865 125 68 0,000 0,22928867 0,2378907 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,22928867 0,23778816 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,22928867 0,23768571 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,22928867 0,23758335 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,22928867 0,23748107 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,23223824 0,24043253 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,23223824 0,24032912 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,23223824 0,2402258 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,23223824 0,24012257 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,23223824 0,24001942 ! appendage morphogenesis GO:0035107 135 70 0,000 0,23517663 0,2429519 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,23810386 0,24587034 ! appendage development GO:0048736 136 71 0,000 0,23810386 0,24576486 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,23810386 0,24565948 ! B cell activation GO:0042113 160 71 0,000 0,23810386 0,24555418 ! acute inflammatory response GO:0002526 113 72 0,000 0,24101999 0,24845506 ! regulation of caspase activity GO:0043281 122 72 0,000 0,24101999 0,24834865 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,24101999 0,24824234 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,24101999 0,24813612 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,24392506 0,25101954 ! axon guidance GO:0007411 139 73 0,000 0,24392506 0,25091223 ! fertilization GO:0009566 90 73 0,000 0,24392506 0,250805 ! transition metal ion transport GO:0000041 126 74 0,000 0,2468191 0,25367226 ! neurotransmitter transport GO:0006836 123 74 0,000 0,2468191 0,25356395 ! meiosis GO:0007126 121 74 0,000 0,2468191 0,25345572 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,2468191 0,2533476 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,2468191 0,25323956 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,2468191 0,25313161 ! eye development GO:0001654 143 74 0,000 0,2468191 0,25302376 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,24970216 0,25587028 ! meiotic cell cycle GO:0051321 122 75 0,000 0,24970216 0,25576135 ! rhythmic process GO:0048511 128 75 0,000 0,24970216 0,25565251 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,24970216 0,25554377 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,25257429 0,25837318 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,25257429 0,25826338 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,25257429 0,25815367 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,25543551 0,26096723 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,25543551 0,26085646 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,25828587 0,26365541 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,25828587 0,2635436 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,26112542 0,266328 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,26112542 0,26621515 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,26395419 0,26898508 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,26395419 0,2688712 ! digestion GO:0007586 112 81 0,000 0,26677222 0,27162673 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,26677222 0,27151183 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,26957956 0,27425303 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,26957956 0,27413711 ! response to drug GO:0042493 143 82 0,000 0,26957956 0,2740213 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,26957956 0,27390558 ! regulation of lyase activity GO:0051339 160 83 0,000 0,27237624 0,27663032 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,27516231 0,27934199 ! negative regulation of growth GO:0045926 155 84 0,000 0,27516231 0,27922417 ! regulation of ligase activity GO:0051340 142 84 0,000 0,27516231 0,27910645 ! response to unfolded protein GO:0006986 131 85 0,000 0,2779378 0,28180292 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,2779378 0,28168422 ! amine biosynthetic process GO:0009309 138 86 0,000 0,28070275 0,28436666 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,28070275 0,28424698 ! alcohol catabolic process GO:0046164 130 86 0,000 0,28070275 0,2841274 ! amine transport GO:0015837 155 86 0,000 0,28070275 0,28400792 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,28345721 0,28667426 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of protein transport GO:0051223 154 87 0,000 0,28345721 0,2865538 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,28620122 0,28920627 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,28620122 0,28908486 ! cellular defense response GO:0006968 114 89 0,000 0,2889348 0,29172351 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,29165801 0,29434949 ! sterol metabolic process GO:0016125 152 91 0,000 0,29437088 0,29696283 ! response to protein stimulus GO:0051789 149 91 0,000 0,29437088 0,29683836 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,29437088 0,29671401 ! regulation of defense response GO:0031347 149 92 0,000 0,29707345 0,2993127 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,29707345 0,29918741 ! vitamin metabolic process GO:0006766 139 92 0,000 0,29707345 0,29906223 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,29976576 0,30164635 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,29976576 0,30152024 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,30244784 0,30409089 ! female pregnancy GO:0007565 164 94 0,000 0,30244784 0,30396387 ! transcription initiation GO:0006352 153 94 0,000 0,30244784 0,30383696 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,3077815 0,30906606 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,3077815 0,30893713 ! detection of stimulus GO:0051606 151 96 0,000 0,3077815 0,30880829 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,31043315 0,31133896 ! hormone metabolic process GO:0042445 157 97 0,000 0,31043315 0,31120923 ! regulation of protein localization GO:0032880 176 97 0,000 0,31043315 0,31107962 ! response to virus GO:0009615 160 98 0,000 0,31307473 0,31359608 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,31307473 0,31346558 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,31307473 0,31333519 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,31570627 0,31583754 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,31570627 0,31570627