pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1091-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nucleosome disassembly GO:0006337 14 8 3,000 1,739E-09 4,249E-06 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! regulation of histone modification GO:0031056 14 9 3,000 3,125E-09 3,818E-06 ! cellular macromolecular complex disassembly GO:0034623 44 21 3,000 1,454E-07 1,184E-04 ! macromolecular complex disassembly GO:0032984 54 26 3,000 3,601E-07 2,199E-04 ! regulation of chromosome organization GO:0033044 49 27 3,000 4,22E-07 2,062E-04 ! negative regulation of protein modification process GO:0031400 66 28 3,000 4,914E-07 2,001E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 6,332E-07 2,21E-04 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 1,352E-06 4,13E-04 ! nucleosome assembly GO:0006334 126 87 4,000 1,731E-06 4,698E-04 ! chromatin assembly GO:0031497 128 88 4,000 1,832E-06 4,475E-04 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 2,000 1,857E-06 4,123E-04 ! protein-DNA complex assembly GO:0065004 134 92 4,000 2,283E-06 4,648E-04 ! zymogen activation GO:0031638 18 12 2,000 2,471E-06 4,644E-04 ! nucleosome organization GO:0034728 143 95 4,000 2,676E-06 4,669E-04 ! cellular component disassembly GO:0022411 89 48 3,000 4,511E-06 7,347E-04 ! positive regulation of oxidoreductase activity GO:0051353 22 15 2,000 5,086E-06 7,766E-04 ! endothelial cell migration GO:0043542 31 17 2,000 7,576E-06 1,089E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 2,229E-05 3,025E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 2,854E-05 3,67E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 3,206E-05 3,916E-03 ! negative regulation of organelle organization GO:0010639 181 80 3,000 3,469E-05 4,036E-03 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 3,584E-05 3,98E-03 ! response to hypoxia GO:0001666 178 81 3,000 3,643E-05 3,87E-03 ! somitogenesis GO:0001756 52 29 2,000 3,991E-05 4,063E-03 ! response to oxygen levels GO:0070482 183 83 3,000 4,01E-05 3,919E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 4,894E-05 4,598E-03 ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 5,106E-05 4,62E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 5,106E-05 4,455E-03 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 5,106E-05 4,302E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 5,106E-05 4,158E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 5,106E-05 4,024E-03 ! mRNA transcription GO:0009299 10 5 1,000 5,106E-05 3,898E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 5,106E-05 3,78E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 5,106E-05 3,669E-03 ! collagen metabolic process GO:0032963 49 32 2,000 5,391E-05 3,763E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 2,000 7,079E-05 4,804E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 7,648E-05 5,05E-03 ! embryonic hemopoiesis GO:0035162 16 6 1,000 7,648E-05 4,917E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 7,648E-05 4,791E-03 ! interaction with symbiont GO:0051702 14 6 1,000 7,648E-05 4,671E-03 ! oxygen homeostasis GO:0032364 10 6 1,000 7,648E-05 4,557E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 7,648E-05 4,449E-03 ! tissue remodeling GO:0048771 78 37 2,000 8,377E-05 4,759E-03 ! glycogen metabolic process GO:0005977 63 38 2,000 9,08E-05 5,041E-03 ! glucan metabolic process GO:0044042 64 39 2,000 9,82E-05 5,331E-03 GO:0006073|cellular glucan metabolic process, ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,069E-04 5,678E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,069E-04 5,558E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,069E-04 5,442E-03 GO:0043489|RNA stabilization, ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 1,069E-04 5,331E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 1,069E-04 5,224E-03 ! multicellular organismal metabolic process GO:0044236 64 41 2,000 1,142E-04 5,469E-03 ! segmentation GO:0035282 78 43 2,000 1,317E-04 6,189E-03 ! energy reserve metabolic process GO:0006112 76 44 2,000 1,411E-04 6,506E-03 ! male meiosis GO:0007140 9 8 1,000 1,423E-04 6,44E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,423E-04 6,323E-03 ! hemoglobin metabolic process GO:0020027 14 8 1,000 1,423E-04 6,21E-03 ! ER overload response GO:0006983 13 8 1,000 1,423E-04 6,101E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,423E-04 5,996E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,423E-04 5,894E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,423E-04 5,796E-03 ! gas homeostasis GO:0033483 14 8 1,000 1,423E-04 5,701E-03 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 1,000 1,423E-04 5,609E-03 ! negative regulation of DNA replication initiation GO:0032297 10 8 1,000 1,423E-04 5,52E-03 GO:0000076|DNA replication checkpoint, ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,613E-04 6,155E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,827E-04 6,868E-03 ! induction of positive chemotaxis GO:0050930 17 9 1,000 1,827E-04 6,764E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 1,827E-04 6,663E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,827E-04 6,565E-03 ! mitochondrion localization GO:0051646 18 9 1,000 1,827E-04 6,47E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 2,281E-04 7,961E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 2,281E-04 7,848E-03 ! lung alveolus development GO:0048286 26 10 1,000 2,281E-04 7,739E-03 ! glucan biosynthetic process GO:0009250 14 10 1,000 2,281E-04 7,633E-03 GO:0005978|glycogen biosynthetic process, ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 1,000 2,281E-04 7,53E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 2,281E-04 7,43E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 2,281E-04 7,332E-03 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 2,281E-04 7,237E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 2,281E-04 7,144E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of angiogenesis GO:0045765 125 54 2,000 2,6E-04 8,042E-03 ! regulation of cell shape GO:0008360 142 54 2,000 2,6E-04 7,941E-03 ! response to UV GO:0009411 120 55 2,000 2,746E-04 8,282E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,784E-04 8,293E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 2,784E-04 8,194E-03 ! blood vessel remodeling GO:0001974 30 11 1,000 2,784E-04 8,096E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,784E-04 8,001E-03 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 2,784E-04 7,908E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 2,784E-04 7,817E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 3,053E-04 8,474E-03 ! regulation of bone remodeling GO:0046850 143 57 2,000 3,053E-04 8,379E-03 ! positive regulation of cell migration GO:0030335 137 58 2,000 3,214E-04 8,724E-03 ! cellular polysaccharide metabolic process GO:0044264 93 58 2,000 3,214E-04 8,628E-03 ! regulation of tissue remodeling GO:0034103 146 58 2,000 3,214E-04 8,534E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 3,336E-04 8,762E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 3,336E-04 8,669E-03 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 3,336E-04 8,578E-03 GO:0050927|positive regulation of positive chemotaxis, ! histone acetylation GO:0016573 27 12 1,000 3,336E-04 8,488E-03 ! regulation of hormone metabolic process GO:0032350 28 12 1,000 3,336E-04 8,401E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,336E-04 8,315E-03 ! regulation of leukocyte migration GO:0002685 29 12 1,000 3,336E-04 8,231E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 3,336E-04 8,149E-03 ! embryonic placenta development GO:0001892 21 12 1,000 3,336E-04 8,068E-03 ! regulation of homeostatic process GO:0032844 148 62 2,000 3,913E-04 9,373E-03 ! regulation of chemokine production GO:0032642 18 13 1,000 3,936E-04 9,336E-03 ! positive regulation of cell growth GO:0030307 24 13 1,000 3,936E-04 9,246E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 3,936E-04 9,158E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 3,936E-04 9,072E-03 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 3,936E-04 8,987E-03 ! regulation of mRNA stability GO:0043488 32 13 1,000 3,936E-04 8,904E-03 ! positive regulation of cell motion GO:0051272 157 65 2,000 4,498E-04 0,01008051 ! regulation of RNA stability GO:0043487 33 14 1,000 4,585E-04 0,0101837 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 5,283E-04 0,01162734 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 5,283E-04 0,01152353 ! muscle maintenance GO:0046716 26 15 1,000 5,283E-04 0,01142155 ! cell killing GO:0001906 32 15 1,000 5,283E-04 0,01132136 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 5,283E-04 0,01122291 ! lung development GO:0030324 165 69 2,000 5,36E-04 0,01128767 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 6,029E-04 0,01258829 ! positive regulation of cell size GO:0045793 29 16 1,000 6,029E-04 0,01248161 ! heterophilic cell adhesion GO:0007157 43 16 1,000 6,029E-04 0,01237672 ! DNA replication initiation GO:0006270 28 16 1,000 6,029E-04 0,01227359 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 6,029E-04 0,01217215 ! respiratory tube development GO:0030323 171 72 2,000 6,071E-04 0,01215696 ! respiratory system development GO:0060541 175 74 2,000 6,577E-04 0,01306339 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 6,823E-04 0,01344145 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 6,823E-04 0,01333392 ! heart looping GO:0001947 34 18 1,000 7,664E-04 0,01485961 ! response to retinoic acid GO:0032526 31 18 1,000 7,664E-04 0,0147426 ! cell-substrate junction assembly GO:0007044 56 18 1,000 7,664E-04 0,01462743 ! neural crest cell migration GO:0001755 41 18 1,000 7,664E-04 0,01451404 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 7,664E-04 0,01440239 ! memory GO:0007613 34 19 1,000 8,553E-04 0,0159503 ! pigmentation during development GO:0048066 42 19 1,000 8,553E-04 0,01582947 ! response to vitamin A GO:0033189 32 19 1,000 8,553E-04 0,01571045 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 8,553E-04 0,01559321 ! peptide cross-linking GO:0018149 39 19 1,000 8,553E-04 0,0154777 ! positive regulation of angiogenesis GO:0045766 50 20 1,000 9,489E-04 0,01704577 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 9,489E-04 0,01692135 ! protein amino acid acetylation GO:0006473 41 20 1,000 9,489E-04 0,01679873 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 9,489E-04 0,01667788 ! response to vitamin GO:0033273 36 20 1,000 9,489E-04 0,01655875 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 9,489E-04 0,01644131 GO:0010675|regulation of cellular carbohydrate metabolic process, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 9,489E-04 0,01632553 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 9,489E-04 0,01621136 ! binding of sperm to zona pellucida GO:0007339 22 20 1,000 9,489E-04 0,01609878 ! digestion GO:0007586 130 84 2,000 9,511E-04 0,01602401 ! negative regulation of growth GO:0045926 168 85 2,000 9,843E-04 0,01646953 ! lipid phosphorylation GO:0046834 43 21 1,000 1,047E-03 0,01740451 ! collagen catabolic process GO:0030574 29 21 1,000 1,047E-03 0,01728691 ! sperm-egg recognition GO:0035036 23 21 1,000 1,047E-03 0,01717089 ! cellular response to starvation GO:0009267 37 22 1,000 1,15E-03 0,01873435 ! positive regulation of locomotion GO:0040017 44 22 1,000 1,15E-03 0,01861028 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of intracellular transport GO:0032388 42 22 1,000 1,15E-03 0,01848784 ! peptidyl-serine modification GO:0018209 50 22 1,000 1,15E-03 0,01836701 ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,15E-03 0,01824774 ! regulation of chemotaxis GO:0050920 45 23 1,000 1,258E-03 0,01982735 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 1,258E-03 0,01970026 ! cell-cell recognition GO:0009988 28 23 1,000 1,258E-03 0,01957478 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 1,276E-03 0,01973483 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 1,37E-03 0,02105456 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 1,37E-03 0,02092297 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,37E-03 0,02079301 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 1,484E-03 0,02237611 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 1,487E-03 0,02229083 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,487E-03 0,02215491 ! leukocyte adhesion GO:0007159 55 25 1,000 1,487E-03 0,02202063 ! vasculogenesis GO:0001570 49 25 1,000 1,487E-03 0,02188798 ! negative regulation of DNA replication GO:0008156 45 25 1,000 1,487E-03 0,02175691 ! regulation of behavior GO:0050795 48 25 1,000 1,487E-03 0,02162741 ! interaction with host GO:0051701 66 25 1,000 1,487E-03 0,02149943 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 1,609E-03 0,02311987 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 1,609E-03 0,02298466 ! neural crest cell development GO:0014032 59 26 1,000 1,609E-03 0,02285103 GO:0014033|neural crest cell differentiation, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 1,609E-03 0,02271895 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 1,000 1,735E-03 0,02435944 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 1,735E-03 0,02422024 ! multicellular organismal catabolic process GO:0044243 38 27 1,000 1,735E-03 0,02408263 ! response to starvation GO:0042594 47 27 1,000 1,735E-03 0,02394657 ! cellular response to oxidative stress GO:0034599 43 27 1,000 1,735E-03 0,02381204 ! cellular response to nutrient levels GO:0031669 45 27 1,000 1,735E-03 0,02367901 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 1,866E-03 0,02532138 ! protein amino acid acylation GO:0043543 59 28 1,000 1,866E-03 0,02518148 ! sperm motility GO:0030317 37 28 1,000 1,866E-03 0,02504312 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 2,001E-03 0,02671172 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 2,001E-03 0,02656654 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 2,001E-03 0,02642294 ! acute-phase response GO:0006953 50 30 1,000 2,141E-03 0,02811655 ! regulation of B cell activation GO:0050864 55 30 1,000 2,141E-03 0,02796619 ! cell junction assembly GO:0034329 85 31 1,000 2,285E-03 0,02969202 ! iron ion homeostasis GO:0055072 60 31 1,000 2,285E-03 0,02953492 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 1,000 2,434E-03 0,03129189 ! positive regulation of catabolic process GO:0009896 72 32 1,000 2,434E-03 0,03112806 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 2,587E-03 0,03291513 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 2,744E-03 0,03473984 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 2,907E-03 0,03660133 ! placenta development GO:0001890 53 35 1,000 2,907E-03 0,03641363 ! embryonic organ development GO:0048568 67 36 1,000 3,073E-03 0,03830236 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 3,244E-03 0,04022617 ! cell junction organization GO:0034330 96 37 1,000 3,244E-03 0,04002301 ! DNA integrity checkpoint GO:0031570 82 38 1,000 3,419E-03 0,04197229 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 3,419E-03 0,04176243 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 3,419E-03 0,04155466 ! carbohydrate homeostasis GO:0033500 59 39 1,000 3,598E-03 0,04351982 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 3,598E-03 0,04330544 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mesenchymal cell development GO:0014031 94 41 1,000 3,97E-03 0,04754708 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of intracellular protein transport GO:0033157 86 42 1,000 4,163E-03 0,04960776 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 4,359E-03 0,05169888 GO:0090047|positive regulation of transcription regulator activity, ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 4,359E-03 0,05144913 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 4,56E-03 0,05356101 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 4,765E-03 0,05570194 ! maintenance of location in cell GO:0051651 101 45 1,000 4,765E-03 0,0554367 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 4,975E-03 0,05759701 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 4,975E-03 0,05732532 ! polysaccharide biosynthetic process GO:0000271 79 46 1,000 4,975E-03 0,05705619 ! pigmentation GO:0043473 103 46 1,000 4,975E-03 0,05678957 ! positive regulation of protein transport GO:0051222 80 46 1,000 4,975E-03 0,05652543 ! response to insulin stimulus GO:0032868 98 47 1,000 5,188E-03 0,05867791 ! positive regulation of DNA binding GO:0043388 83 48 1,000 5,406E-03 0,06085733 ! vascular process in circulatory system GO:0003018 85 48 1,000 5,406E-03 0,06057816 ! JNK cascade GO:0007254 106 49 1,000 5,627E-03 0,06277513 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 5,627E-03 0,06248979 ! regulation of ossification GO:0030278 123 50 1,000 5,853E-03 0,06470372 ! positive regulation of cytokine production GO:0001819 94 50 1,000 5,853E-03 0,06441226 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 6,083E-03 0,06664259 ! positive regulation of binding GO:0051099 88 52 1,000 6,317E-03 0,06889747 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 6,317E-03 0,06859126 ! histone modification GO:0016570 104 52 1,000 6,317E-03 0,06828775 ! positive regulation of growth GO:0045927 96 53 1,000 6,555E-03 0,07054926 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 6,555E-03 0,07023983 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 1,000 6,555E-03 0,06993311 ! covalent chromatin modification GO:0016569 115 54 1,000 6,797E-03 0,07220085 ! cell recognition GO:0008037 98 55 1,000 7,044E-03 0,07449147 ! regulation of DNA replication GO:0006275 105 56 1,000 7,294E-03 0,07680447 ! heart morphogenesis GO:0003007 105 57 1,000 7,548E-03 0,07913935 ! regulation of intracellular transport GO:0032386 108 57 1,000 7,548E-03 0,07880115 ! maintenance of location GO:0051235 124 58 1,000 7,806E-03 0,08114885 ! lipid modification GO:0030258 112 60 1,000 8,334E-03 0,08627058 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 8,604E-03 0,08868831 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 9,437E-03 0,09686447 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 9,437E-03 0,09645917 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,01030397 0,10488579 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 0,01030397 0,10445058 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,01060065 0,10701397 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! adaptive immune response GO:0002250 126 68 1,000 0,01060065 0,10657358 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,01060065 0,1061368 ! negative regulation of cell size GO:0045792 144 69 1,000 0,01090109 0,10869939 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 0,01090109 0,10825752 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,01090109 0,10781923 ! single fertilization GO:0007338 83 69 1,000 0,01090109 0,10738448 ! negative regulation of kinase activity GO:0033673 145 70 1,000 0,01120526 0,10993758 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01134315 0,11084526 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01134315 0,11040364 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01134315 0,10996553 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01134315 0,10953089 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01134315 0,10909966 ! neuron fate determination GO:0048664 7 5 0,000 0,01134315 0,10867182 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01134315 0,10824732 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01134315 0,10782612 ! polyol transport GO:0015791 12 5 0,000 0,01134315 0,10740819 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01134315 0,10699349 ! response to superoxide GO:0000303 10 5 0,000 0,01134315 0,10658198 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01134315 0,10617362 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01134315 0,10576837 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01134315 0,10536621 ! female meiosis GO:0007143 10 5 0,000 0,01134315 0,1049671 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01134315 0,104571 ! hypothalamus development GO:0021854 9 5 0,000 0,01134315 0,10417787 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01134315 0,10378769 ! cobalt ion transport GO:0006824 11 5 0,000 0,01134315 0,10340043 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01134315 0,10301604 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01134315 0,1026345 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01134315 0,10225577 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01134315 0,10187983 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01134315 0,10150665 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01134315 0,10113618 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01134315 0,10076841 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01134315 0,10040331 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01134315 0,10004085 ! transposition GO:0032196 9 5 0,000 0,01134315 0,09968099 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01134315 0,09932371 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01134315 0,09896898 ! negative chemotaxis GO:0050919 16 5 0,000 0,01134315 0,09861678 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01134315 0,09826707 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01134315 0,09791984 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01134315 0,09757505 ! behavioral response to pain GO:0048266 10 5 0,000 0,01134315 0,09723268 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01134315 0,09689271 ! Notch receptor processing GO:0007220 11 5 0,000 0,01134315 0,0965551 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01134315 0,09621984 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01134315 0,0958869 ! micturition GO:0060073 9 5 0,000 0,01134315 0,09555626 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01134315 0,09522788 ! copulation GO:0007620 9 5 0,000 0,01134315 0,09490176 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01134315 0,09457786 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01134315 0,09425617 ! bioluminescence GO:0008218 9 5 0,000 0,01134315 0,09393666 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01134315 0,0936193 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01134315 0,09330409 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01134315 0,09299099 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01134315 0,09267998 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01134315 0,09237105 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01134315 0,09206417 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01134315 0,09175932 ! grooming behavior GO:0007625 6 5 0,000 0,01134315 0,09145648 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01134315 0,09115564 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01134315 0,09085677 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01134315 0,09055985 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01134315 0,09026487 ! response to protozoan GO:0001562 13 5 0,000 0,01134315 0,0899718 ! lymph vessel development GO:0001945 10 5 0,000 0,01134315 0,08968063 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01134315 0,08939134 ! endochondral ossification GO:0001958 17 5 0,000 0,01134315 0,0891039 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01134315 0,08881831 ! single strand break repair GO:0000012 8 5 0,000 0,01134315 0,08853455 ! parathyroid gland development GO:0060017 14 5 0,000 0,01134315 0,08825259 ! anagen GO:0042640 7 5 0,000 0,01134315 0,08797243 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01134315 0,08769403 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01134315 0,08741739 ! cytokine secretion GO:0050663 15 5 0,000 0,01134315 0,0871425 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01134315 0,08686932 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01134315 0,08659786 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01134315 0,08632808 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01134315 0,08605998 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01134315 0,08579354 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01134315 0,08552875 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01134315 0,08526558 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01134315 0,08500403 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01134315 0,08474408 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01134315 0,08448571 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01134315 0,08422892 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01134315 0,08397368 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01134315 0,08371998 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01134315 0,08346781 ! microvillus organization GO:0032528 8 5 0,000 0,01134315 0,08321716 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01134315 0,08296801 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01134315 0,08272034 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01134315 0,08247415 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01134315 0,08222942 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01134315 0,08198614 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01134315 0,08174429 ! polyol catabolic process GO:0046174 9 5 0,000 0,01134315 0,08150387 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01134315 0,08126485 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01134315 0,08102723 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01134315 0,080791 ! muscle cell migration GO:0014812 8 5 0,000 0,01134315 0,08055615 ! mitochondrial fission GO:0000266 8 5 0,000 0,01134315 0,08032265 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01134315 0,0800905 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01134315 0,07985969 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01134315 0,07963021 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01134315 0,07940205 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01134315 0,07917518 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01134315 0,07894961 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01134315 0,07872532 ! monocyte activation GO:0042117 10 5 0,000 0,01134315 0,07850231 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01134315 0,07828055 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01134315 0,07806004 ! response to food GO:0032094 6 5 0,000 0,01134315 0,07784077 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01134315 0,07762273 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01134315 0,07740591 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01134315 0,07719029 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01134315 0,07697587 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01134315 0,07676264 ! forebrain neuron development GO:0021884 13 5 0,000 0,01134315 0,07655059 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01134315 0,07633971 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01134315 0,07612998 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01134315 0,07592141 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01134315 0,07571397 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01134315 0,07550767 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01134315 0,07530248 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01134315 0,07509841 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01134315 0,07489544 ! lipid glycosylation GO:0030259 7 5 0,000 0,01134315 0,07469357 ! nucleobase transport GO:0015851 6 5 0,000 0,01134315 0,07449278 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01134315 0,07429307 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01134315 0,07409442 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01134315 0,07389684 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01134315 0,0737003 ! basic amino acid transport GO:0015802 12 5 0,000 0,01134315 0,07350481 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01134315 0,07331035 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01134315 0,07311692 ! actin nucleation GO:0045010 11 5 0,000 0,01134315 0,07292451 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01134315 0,07273311 ! depurination GO:0045007 5 5 0,000 0,01134315 0,07254271 ! depyrimidination GO:0045008 10 5 0,000 0,01134315 0,0723533 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01134315 0,07216488 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01134315 0,07197744 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01134315 0,07179097 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01134315 0,07160546 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01134315 0,07142091 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01134315 0,07123731 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01134315 0,07105465 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01134315 0,07087293 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01134315 0,07069213 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01134315 0,07051225 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01134315 0,07033328 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01134315 0,07015523 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01134315 0,06997807 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01134315 0,0698018 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01134315 0,06962642 ! response to arsenic GO:0046685 11 5 0,000 0,01134315 0,06945192 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01134315 0,06927829 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01134315 0,06910552 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01134315 0,06893362 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01134315 0,06876257 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01134315 0,06859236 ! response to mercury ion GO:0046689 8 5 0,000 0,01134315 0,068423 ! response to cadmium ion GO:0046686 7 5 0,000 0,01134315 0,06825447 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01134315 0,06808677 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01134315 0,06791989 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01134315 0,06775382 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01134315 0,06758857 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01134315 0,06742412 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01134315 0,06726047 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01134315 0,06709761 ! decidualization GO:0046697 11 5 0,000 0,01134315 0,06693554 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01134315 0,06677425 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01134315 0,06661374 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01134315 0,06645399 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01134315 0,06629501 ! embryonic cleavage GO:0040016 6 5 0,000 0,01134315 0,06613679 ! peroxisome fission GO:0016559 5 5 0,000 0,01134315 0,06597932 ! histone demethylation GO:0016577 13 5 0,000 0,01134315 0,0658226 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01134315 0,06566662 ! mitotic recombination GO:0006312 9 5 0,000 0,01134315 0,06551138 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01134315 0,06535687 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01134315 0,06520309 ! metaphase plate congression GO:0051310 7 5 0,000 0,01134315 0,06505003 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01134315 0,06489769 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01134315 0,06474606 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01134315 0,06459514 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01134315 0,06444492 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01134315 0,06429539 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01134315 0,06414656 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01134315 0,06399842 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01134315 0,06385095 ! B cell homeostasis GO:0001782 13 5 0,000 0,01134315 0,06370417 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01134315 0,06355806 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01134315 0,06341262 ! metaphase GO:0051323 11 5 0,000 0,01134315 0,06326784 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01134315 0,06312372 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01134315 0,06298026 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01134315 0,06283745 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01134315 0,06269528 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01134315 0,06255376 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01134315 0,06241287 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01134315 0,06227262 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01134315 0,06213299 ! response to redox state GO:0051775 6 5 0,000 0,01134315 0,06199399 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01134315 0,06185561 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01134315 0,06171785 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01134315 0,0615807 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01134315 0,06144416 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01134315 0,06130822 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01134315 0,06117288 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01134315 0,06103814 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01134315 0,06090399 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01134315 0,06077043 ! striatum development GO:0021756 14 5 0,000 0,01134315 0,06063745 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01134315 0,06050505 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01134315 0,06037323 ! glial cell migration GO:0008347 10 5 0,000 0,01134315 0,06024199 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01134315 0,06011131 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01134315 0,0599812 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01134315 0,05985165 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01134315 0,05972266 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01134315 0,05959422 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01134315 0,05946634 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01134315 0,059339 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01134315 0,05921221 ! neuroprotection GO:0043526 8 5 0,000 0,01134315 0,05908596 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01134315 0,05896024 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01134315 0,05883506 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01134315 0,05871041 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01134315 0,05858629 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01134315 0,05846269 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01134315 0,05833961 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01134315 0,05821705 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01134315 0,058095 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01134315 0,05797346 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01134315 0,05785243 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01134315 0,0577319 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01134315 0,05761188 ! spindle assembly GO:0051225 6 5 0,000 0,01134315 0,05749235 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01134315 0,05737332 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01134315 0,05725478 ! protein palmitoylation GO:0018345 12 5 0,000 0,01134315 0,05713673 ! drug metabolic process GO:0017144 7 5 0,000 0,01134315 0,05701916 ! stem cell division GO:0017145 11 5 0,000 0,01134315 0,05690208 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01134315 0,05678548 ! organ regeneration GO:0031100 7 5 0,000 0,01134315 0,05666935 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01134315 0,0565537 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01134315 0,05643852 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,01151316 0,05716799 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,01182476 0,05859614 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,01182476 0,05847752 ! acute inflammatory response GO:0002526 118 74 1,000 0,012459 0,06148959 ! negative regulation of transferase activity GO:0051348 155 74 1,000 0,012459 0,06136562 ! organelle localization GO:0051640 155 74 1,000 0,012459 0,06124214 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01278161 0,06270173 GO:0090046|regulation of transcription regulator activity, ! cell-matrix adhesion GO:0007160 181 76 1,000 0,01310784 0,06417325 ! learning or memory GO:0007611 161 76 1,000 0,01310784 0,06404491 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01343769 0,06552549 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,01343769 0,06539496 ! regulation of catabolic process GO:0009894 173 77 1,000 0,01343769 0,06526495 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01359648 0,06590517 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01359648 0,06577467 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01359648 0,06564468 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01359648 0,0655152 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01359648 0,06538623 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01359648 0,06525777 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01359648 0,06512982 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01359648 0,06500236 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01359648 0,0648754 ! response to oxygen radical GO:0000305 11 6 0,000 0,01359648 0,06474894 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01359648 0,06462297 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01359648 0,06449749 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01359648 0,06437249 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01359648 0,06424798 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01359648 0,06412395 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01359648 0,0640004 ! forebrain regionalization GO:0021871 9 6 0,000 0,01359648 0,06387732 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01359648 0,06375472 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01359648 0,06363258 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01359648 0,06351091 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01359648 0,06338971 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01359648 0,06326897 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01359648 0,06314868 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01359648 0,06302886 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01359648 0,06290948 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01359648 0,06279056 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01359648 0,06267209 ! malate metabolic process GO:0006108 13 6 0,000 0,01359648 0,06255406 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01359648 0,06243648 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01359648 0,06231934 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01359648 0,06220263 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01359648 0,06208637 ! protein refolding GO:0042026 15 6 0,000 0,01359648 0,06197054 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01359648 0,06185513 ! opsonization GO:0008228 8 6 0,000 0,01359648 0,06174016 ! mating behavior GO:0007617 7 6 0,000 0,01359648 0,06162562 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01359648 0,06151149 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01359648 0,06139779 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01359648 0,06128451 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01359648 0,06117165 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01359648 0,0610592 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01359648 0,06094717 ! toxin metabolic process GO:0009404 11 6 0,000 0,01359648 0,06083554 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01359648 0,06072433 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01359648 0,06061352 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01359648 0,06050311 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01359648 0,0603931 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01359648 0,0602835 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01359648 0,06017429 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01359648 0,06006547 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01359648 0,05995705 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01359648 0,05984902 ! thymic T cell selection GO:0045061 16 6 0,000 0,01359648 0,05974138 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01359648 0,05963412 ! protein lipoylation GO:0009249 10 6 0,000 0,01359648 0,05952725 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01359648 0,05942076 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01359648 0,05931466 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01359648 0,05920892 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01359648 0,05910357 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01359648 0,05899859 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01359648 0,05889398 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01359648 0,05878975 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01359648 0,05868588 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01359648 0,05858238 ! hyperosmotic response GO:0006972 10 6 0,000 0,01359648 0,05847924 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01359648 0,05837646 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01359648 0,05827405 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01359648 0,05817199 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01359648 0,05807029 ! urea metabolic process GO:0019627 7 6 0,000 0,01359648 0,05796895 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01359648 0,05786796 ! neutrophil activation GO:0042119 7 6 0,000 0,01359648 0,05776732 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01359648 0,05766703 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01359648 0,05756708 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01359648 0,05746749 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01359648 0,05736823 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01359648 0,05726932 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01359648 0,05717075 ! neuron apoptosis GO:0051402 15 6 0,000 0,01359648 0,05707252 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01359648 0,05697463 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01359648 0,05687707 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01359648 0,05677984 ! carnitine transport GO:0015879 10 6 0,000 0,01359648 0,05668295 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01359648 0,05658638 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01359648 0,05649015 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01359648 0,05639424 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01359648 0,05629866 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01359648 0,0562034 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01359648 0,05610846 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01359648 0,05601384 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01359648 0,05591954 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01359648 0,05582556 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01359648 0,05573189 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01359648 0,05563854 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01359648 0,0555455 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01359648 0,05545277 ! response to UV-C GO:0010225 14 6 0,000 0,01359648 0,05536034 ! astrocyte development GO:0014002 16 6 0,000 0,01359648 0,05526823 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01359648 0,05517642 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01359648 0,05508492 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01359648 0,05499372 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01359648 0,05490282 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01359648 0,05481222 ! response to copper ion GO:0046688 10 6 0,000 0,01359648 0,05472192 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01359648 0,05463192 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01359648 0,05454221 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01359648 0,0544528 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01359648 0,05436368 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01359648 0,05427485 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01359648 0,05418631 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01359648 0,05409806 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01359648 0,05401009 ! hair follicle maturation GO:0048820 8 6 0,000 0,01359648 0,05392241 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01359648 0,05383502 ! Schwann cell development GO:0014044 15 6 0,000 0,01359648 0,05374791 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01359648 0,05366108 ! response to pheromone GO:0019236 6 6 0,000 0,01359648 0,05357453 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01359648 0,05348826 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01359648 0,05340226 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01359648 0,05331654 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01359648 0,0532311 ! subpallium development GO:0021544 15 6 0,000 0,01359648 0,05314593 ! neural tube patterning GO:0021532 8 6 0,000 0,01359648 0,05306103 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01359648 0,05297641 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01359648 0,05289205 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01359648 0,05280796 ! G2 phase GO:0051319 16 6 0,000 0,01359648 0,05272414 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01359648 0,05264058 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01359648 0,05255729 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01359648 0,05247426 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01359648 0,05239149 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01359648 0,05230899 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01359648 0,05222674 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01359648 0,05214475 ! receptor internalization GO:0031623 11 6 0,000 0,01359648 0,05206302 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01359648 0,05198154 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01359648 0,05190032 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01359648 0,05181936 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01359648 0,05173864 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01359648 0,05165818 ! protein deubiquitination GO:0016579 16 6 0,000 0,01359648 0,05157796 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01359648 0,051498 ! protein destabilization GO:0031648 9 6 0,000 0,01359648 0,05141828 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01359648 0,05133881 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01359648 0,05125958 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01359648 0,0511806 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01359648 0,05110186 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01359648 0,05102336 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01359648 0,0509451 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01359648 0,05086709 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01359648 0,05078931 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01359648 0,05071177 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01359648 0,05063446 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01359648 0,05055739 ! neural plate development GO:0001840 9 6 0,000 0,01359648 0,05048056 ! catecholamine transport GO:0051937 9 6 0,000 0,01359648 0,05040396 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01359648 0,05032759 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01359648 0,05025145 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01359648 0,05017554 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01359648 0,05009986 ! maternal placenta development GO:0001893 12 6 0,000 0,01359648 0,05002441 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01359648 0,04994918 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01359648 0,04987418 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01359648 0,04979941 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01359648 0,04972486 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01359648 0,04965053 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01359648 0,04957643 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01359648 0,04950254 GO:0055081|anion homeostasis, ! fertilization GO:0009566 99 78 1,000 0,01377113 0,0500638 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,01377113 0,04998941 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,01410815 0,05113682 ! protein oligomerization GO:0051259 149 79 1,000 0,01410815 0,05106106 ! meiosis GO:0007126 143 81 1,000 0,01479286 0,05345999 GO:0051327|M phase of meiotic cell cycle, ! cell-substrate adhesion GO:0031589 189 82 1,000 0,01514051 0,05463554 ! meiotic cell cycle GO:0051321 144 82 1,000 0,01514051 0,05455496 ! tRNA transcription GO:0009304 17 7 0,000 0,01584474 0,05700841 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01584474 0,05692457 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01584474 0,05684098 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01584474 0,05675764 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01584474 0,05667454 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01584474 0,05659168 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01584474 0,05650906 ! sleep GO:0030431 16 7 0,000 0,01584474 0,05642669 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01584474 0,05634455 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01584474 0,05626266 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01584474 0,056181 ! prostate gland development GO:0030850 14 7 0,000 0,01584474 0,05609958 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01584474 0,05601839 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01584474 0,05593744 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01584474 0,05585672 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01584474 0,05577624 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01584474 0,05569598 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01584474 0,05561596 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01584474 0,05553617 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01584474 0,0554566 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01584474 0,05537726 ! glycolipid transport GO:0046836 11 7 0,000 0,01584474 0,05529815 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01584474 0,05521927 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,01584474 0,05514061 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01584474 0,05506217 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01584474 0,05498396 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01584474 0,05490597 ! pericardium development GO:0060039 16 7 0,000 0,01584474 0,0548282 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01584474 0,05475065 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01584474 0,05467332 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01584474 0,0545962 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01584474 0,05451931 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01584474 0,05444263 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01584474 0,05436616 ! lipoprotein transport GO:0042953 14 7 0,000 0,01584474 0,05428991 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01584474 0,05421388 ! rhythmic behavior GO:0007622 17 7 0,000 0,01584474 0,05413805 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01584474 0,05406244 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01584474 0,05398704 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01584474 0,05391185 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01584474 0,05383687 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01584474 0,05376209 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01584474 0,05368753 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01584474 0,05361317 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01584474 0,05353901 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01584474 0,05346507 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01584474 0,05339132 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01584474 0,05331778 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01584474 0,05324444 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01584474 0,0531713 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01584474 0,05309836 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01584474 0,05302563 ! spinal cord patterning GO:0021511 14 7 0,000 0,01584474 0,05295309 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01584474 0,05288075 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01584474 0,05280861 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01584474 0,05273666 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01584474 0,05266491 ! adrenal gland development GO:0030325 17 7 0,000 0,01584474 0,05259335 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01584474 0,05252199 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01584474 0,05245082 ! ovulation GO:0030728 10 7 0,000 0,01584474 0,05237985 ! adenohypophysis development GO:0021984 11 7 0,000 0,01584474 0,05230906 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01584474 0,05223847 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01584474 0,05216807 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01584474 0,05209786 ! microtubule nucleation GO:0007020 21 7 0,000 0,01584474 0,05202783 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01584474 0,051958 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01584474 0,05188835 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01584474 0,05181889 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01584474 0,05174961 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01584474 0,05168052 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01584474 0,05161161 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01584474 0,05154289 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01584474 0,05147435 ! galactose metabolic process GO:0006012 13 7 0,000 0,01584474 0,05140599 ! vesicle fusion GO:0006906 20 7 0,000 0,01584474 0,05133781 ! response to dietary excess GO:0002021 8 7 0,000 0,01584474 0,05126981 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01584474 0,05120199 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01584474 0,05113436 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01584474 0,0510669 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01584474 0,05099961 ! organ growth GO:0035265 15 7 0,000 0,01584474 0,05093251 ! nucleoside transport GO:0015858 11 7 0,000 0,01584474 0,05086558 ! nucleoside salvage GO:0043174 11 7 0,000 0,01584474 0,05079883 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01584474 0,05073225 ! male sex determination GO:0030238 15 7 0,000 0,01584474 0,05066585 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01584474 0,05059962 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01584474 0,05053356 ! parturition GO:0007567 16 7 0,000 0,01584474 0,05046768 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01584474 0,05040196 ! rRNA modification GO:0000154 14 7 0,000 0,01584474 0,05033642 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01584474 0,05027105 ! spindle checkpoint GO:0031577 16 7 0,000 0,01584474 0,05020585 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01584474 0,05014081 ! monocyte differentiation GO:0030224 16 7 0,000 0,01584474 0,05007595 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01584474 0,05001125 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01584474 0,04994672 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01584474 0,04988236 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01584474 0,04981816 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01584474 0,04975412 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01584474 0,04969025 ! fibrinolysis GO:0042730 11 7 0,000 0,01584474 0,04962655 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01584474 0,04956301 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01584474 0,04949963 ! eating behavior GO:0042755 8 7 0,000 0,01584474 0,04943641 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01584474 0,04937335 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01584474 0,04931046 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01584474 0,04924772 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01584474 0,04918514 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01584474 0,04912273 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01584474 0,04906047 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01584474 0,04899836 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01584474 0,04893642 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01584474 0,04887463 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01584474 0,048813 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01584474 0,04875152 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01584474 0,0486902 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01584474 0,04862903 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01584474 0,04856801 ! histone ubiquitination GO:0016574 9 7 0,000 0,01584474 0,04850715 ! regulation of meiosis GO:0040020 12 7 0,000 0,01584474 0,04844644 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01584474 0,04838588 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01584474 0,04832548 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01584474 0,04826522 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01584474 0,04820512 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01584474 0,04814516 ! transcription termination GO:0006353 14 7 0,000 0,01584474 0,04808535 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01584474 0,04802569 ! anaphase GO:0051322 18 7 0,000 0,01584474 0,04796618 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01584474 0,04790682 ! axonal fasciculation GO:0007413 19 7 0,000 0,01584474 0,0478476 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01584474 0,04778853 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01584474 0,0477296 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01584474 0,04767082 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01584474 0,04761219 ! diuresis GO:0030146 12 7 0,000 0,01584474 0,04755369 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01584474 0,04749535 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01584474 0,04743714 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01584474 0,04737908 ! antibiotic transport GO:0042891 9 7 0,000 0,01584474 0,04732116 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01584474 0,04726338 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01584474 0,04720574 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01584474 0,04714824 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01584474 0,04709089 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01584474 0,04703367 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01584474 0,04697659 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01584474 0,04691965 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01584474 0,04686284 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01584474 0,04680618 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01584474 0,04674965 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01584474 0,04669325 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01584474 0,046637 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01584474 0,04658088 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01584474 0,04652489 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01584474 0,04646904 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01584474 0,04641332 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01584474 0,04635773 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01584474 0,04630228 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01584474 0,04624696 ! muscle adaptation GO:0043500 13 7 0,000 0,01584474 0,04619178 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01584474 0,04613672 ! retina homeostasis GO:0001895 12 7 0,000 0,01584474 0,04608179 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01584474 0,046027 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01584474 0,04597234 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01584474 0,0459178 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01584474 0,0458634 ! response to nutrient GO:0007584 135 84 1,000 0,01584632 0,04581367 ! regulation of ligase activity GO:0051340 147 84 1,000 0,01584632 0,04575951 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,01620444 0,04673842 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,01656601 0,04772497 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 1,000 0,01693103 0,04871909 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 167 89 1,000 0,01767131 0,05078943 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01808794 0,05192579 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01808794 0,05186484 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,01808794 0,05180404 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01808794 0,05174338 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01808794 0,05168286 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01808794 0,05162248 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01808794 0,05156224 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01808794 0,05150215 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01808794 0,05144219 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01808794 0,05138238 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01808794 0,0513227 ! meiotic prophase I GO:0007128 14 8 0,000 0,01808794 0,05126316 ! response to zinc ion GO:0010043 12 8 0,000 0,01808794 0,05120376 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01808794 0,05114449 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01808794 0,05108537 ! oligopeptide transport GO:0006857 16 8 0,000 0,01808794 0,05102638 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01808794 0,05096752 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01808794 0,05090881 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01808794 0,05085022 ! signal peptide processing GO:0006465 12 8 0,000 0,01808794 0,05079177 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01808794 0,05073346 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01808794 0,05067528 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01808794 0,05061723 ! succinate metabolic process GO:0006105 17 8 0,000 0,01808794 0,05055932 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01808794 0,05050154 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01808794 0,05044389 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01808794 0,05038637 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01808794 0,05032898 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01808794 0,05027172 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01808794 0,05021459 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01808794 0,0501576 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01808794 0,05010073 ! reflex GO:0060004 17 8 0,000 0,01808794 0,05004399 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01808794 0,04998738 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01808794 0,0499309 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01808794 0,04987454 ! pigment granule organization GO:0048753 17 8 0,000 0,01808794 0,04981831 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01808794 0,04976221 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01808794 0,04970624 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01808794 0,04965039 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01808794 0,04959466 ! histidine catabolic process GO:0006548 10 8 0,000 0,01808794 0,04953906 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01808794 0,04948359 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01808794 0,04942824 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01808794 0,04937301 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01808794 0,04931791 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01808794 0,04926292 ! melanin metabolic process GO:0006582 17 8 0,000 0,01808794 0,04920807 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01808794 0,04915333 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01808794 0,04909872 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01808794 0,04904422 ! macrophage activation GO:0042116 13 8 0,000 0,01808794 0,04898985 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01808794 0,0489356 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01808794 0,04888146 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01808794 0,04882745 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01808794 0,04877356 ! purine salvage GO:0043101 12 8 0,000 0,01808794 0,04871978 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01808794 0,04866613 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01808794 0,04861259 ! osteoblast development GO:0002076 17 8 0,000 0,01808794 0,04855917 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01808794 0,04850587 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01808794 0,04845268 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01808794 0,04839961 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01808794 0,04834666 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01808794 0,04829382 ! response to UV-B GO:0010224 17 8 0,000 0,01808794 0,0482411 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01808794 0,04818849 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01808794 0,048136 ! intermediate filament organization GO:0045109 12 8 0,000 0,01808794 0,04808362 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01808794 0,04803135 ! cellular extravasation GO:0045123 13 8 0,000 0,01808794 0,0479792 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01808794 0,04792716 ! response to antibiotic GO:0046677 11 8 0,000 0,01808794 0,04787524 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01808794 0,04782342 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01808794 0,04777172 ! DNA topological change GO:0006265 12 8 0,000 0,01808794 0,04772013 ! response to tropane GO:0014073 15 8 0,000 0,01808794 0,04766866 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01808794 0,04761729 ! melanosome transport GO:0032402 13 8 0,000 0,01808794 0,04756603 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01808794 0,04751489 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01808794 0,04746385 ! mast cell activation GO:0045576 14 8 0,000 0,01808794 0,04741292 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01808794 0,0473621 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01808794 0,0473114 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01808794 0,0472608 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01808794 0,0472103 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01808794 0,04715992 ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01808794 0,04710964 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01808794 0,04705947 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01808794 0,04700941 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01808794 0,04695945 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01808794 0,0469096 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01808794 0,04685986 ! response to tumor cell GO:0002347 16 8 0,000 0,01808794 0,04681022 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01808794 0,04676068 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01808794 0,04671125 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01808794 0,04666193 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01808794 0,0466127 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01808794 0,04656359 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01808794 0,04651457 ! hormone catabolic process GO:0042447 17 8 0,000 0,01808794 0,04646566 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01808794 0,04641685 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01808794 0,04636815 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01808794 0,04631954 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01808794 0,04627104 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01808794 0,04622264 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01808794 0,04617434 ! adult feeding behavior GO:0008343 10 8 0,000 0,01808794 0,04612614 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01808794 0,04607804 ! ATP catabolic process GO:0006200 11 8 0,000 0,01808794 0,04603005 ! blastocyst growth GO:0001832 19 8 0,000 0,01808794 0,04598215 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01808794 0,04593435 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01808794 0,04588665 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01808794 0,04583905 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01808794 0,04579155 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01808794 0,04574414 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01808794 0,04569684 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01808794 0,04564963 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01808794 0,04560252 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01808794 0,04555551 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01808794 0,04550859 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01808794 0,04546177 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01808794 0,04541505 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01808794 0,04536842 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01808794 0,04532189 ! protein prenylation GO:0018342 21 8 0,000 0,01808794 0,04527545 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01808794 0,04522911 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01808794 0,04518287 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01808794 0,04513671 ! ossification GO:0001503 205 91 1,000 0,01842514 0,04593125 ! bone development GO:0060348 206 92 1,000 0,0188071 0,04683562 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,0188071 0,04678792 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,01919239 0,04769787 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,01919239 0,0476494 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,019581 0,04856486 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,01997292 0,04948665 ! axon extension GO:0048675 16 9 0,000 0,02032609 0,05031068 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02032609 0,05025976 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02032609 0,05020894 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02032609 0,05015822 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02032609 0,05010761 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02032609 0,0500571 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02032609 0,05000669 ! reproductive behavior GO:0019098 22 9 0,000 0,02032609 0,04995638 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02032609 0,04990617 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02032609 0,04985607 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02032609 0,04980606 ! UTP metabolic process GO:0046051 10 9 0,000 0,02032609 0,04975615 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02032609 0,04970635 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02032609 0,04965664 ! artery development GO:0060840 25 9 0,000 0,02032609 0,04960704 GO:0048844|artery morphogenesis, ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02032609 0,04955753 ! equilibrioception GO:0050957 20 9 0,000 0,02032609 0,04950812 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02032609 0,04945881 ! chemosensory behavior GO:0007635 21 9 0,000 0,02032609 0,04940959 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02032609 0,04936048 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02032609 0,04931146 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02032609 0,04926254 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02032609 0,04921372 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02032609 0,04916499 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02032609 0,04911636 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02032609 0,04906783 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02032609 0,04901939 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02032609 0,04897105 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02032609 0,0489228 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02032609 0,04887465 ! protein targeting to ER GO:0045047 25 9 0,000 0,02032609 0,04882659 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02032609 0,04877863 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02032609 0,04873076 ! T cell selection GO:0045058 27 9 0,000 0,02032609 0,04868298 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02032609 0,0486353 ! glycine catabolic process GO:0006546 15 9 0,000 0,02032609 0,04858771 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02032609 0,04854022 ! endosome organization GO:0007032 20 9 0,000 0,02032609 0,04849281 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02032609 0,0484455 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02032609 0,04839829 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02032609 0,04835116 ! mannose metabolic process GO:0006013 13 9 0,000 0,02032609 0,04830413 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02032609 0,04825718 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02032609 0,04821033 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02032609 0,04816357 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02032609 0,0481169 ! receptor clustering GO:0043113 20 9 0,000 0,02032609 0,04807032 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02032609 0,04802383 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02032609 0,04797743 ! retinol metabolic process GO:0042572 20 9 0,000 0,02032609 0,04793112 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02032609 0,0478849 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02032609 0,04783877 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02032609 0,04779273 ! macrophage differentiation GO:0030225 15 9 0,000 0,02032609 0,04774677 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02032609 0,04770091 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02032609 0,04765513 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02032609 0,04760944 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02032609 0,04756383 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02032609 0,04751832 ! response to amine stimulus GO:0014075 13 9 0,000 0,02032609 0,04747289 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02032609 0,04742755 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02032609 0,04738229 ! erythrocyte development GO:0048821 17 9 0,000 0,02032609 0,04733712 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02032609 0,04729204 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02032609 0,04724704 ! renal water homeostasis GO:0003091 15 9 0,000 0,02032609 0,04720213 ! postreplication repair GO:0006301 25 9 0,000 0,02032609 0,04715731 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02032609 0,04711256 ! icosanoid secretion GO:0032309 15 9 0,000 0,02032609 0,04706791 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02032609 0,04702334 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02032609 0,04697885 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02032609 0,04693444 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02032609 0,04689013 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02032609 0,04684589 ! sterol catabolic process GO:0016127 14 9 0,000 0,02032609 0,04680174 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02032609 0,04675767 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02032609 0,04671368 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02032609 0,04666978 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02032609 0,04662596 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02032609 0,04658222 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02032609 0,04653856 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02032609 0,04649498 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02032609 0,04645149 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02032609 0,04640808 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02032609 0,04636475 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02032609 0,04632149 ! purine base metabolic process GO:0006144 25 9 0,000 0,02032609 0,04627832 ! pigment granule transport GO:0051904 17 9 0,000 0,02032609 0,04623524 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02032609 0,04619223 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02032609 0,0461493 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02032609 0,04610645 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02032609 0,04606368 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02032609 0,04602098 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02032609 0,04597837 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,02076659 0,04693134 ! regulation of protein localization GO:0032880 188 97 1,000 0,02076659 0,04688796 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,02198146 0,04958513 GO:0060538|skeletal muscle organ development, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,0225592 0,05084145 ! regulation of developmental growth GO:0048638 16 10 0,000 0,0225592 0,05079459 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,0225592 0,05074782 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0225592 0,05070113 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,0225592 0,05065453 ! associative learning GO:0008306 21 10 0,000 0,0225592 0,05060802 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0225592 0,05056159 ! phosphate transport GO:0006817 24 10 0,000 0,0225592 0,05051524 ! cell volume homeostasis GO:0006884 17 10 0,000 0,0225592 0,05046899 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,0225592 0,05042281 ! CTP metabolic process GO:0046036 11 10 0,000 0,0225592 0,05037672 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,0225592 0,05033071 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0225592 0,05028479 ! GTP metabolic process GO:0046039 11 10 0,000 0,0225592 0,05023895 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,0225592 0,0501932 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,0225592 0,05014753 ! social behavior GO:0035176 29 10 0,000 0,0225592 0,05010194 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,0225592 0,05005643 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,0225592 0,05001101 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,0225592 0,04996567 ! androgen metabolic process GO:0008209 17 10 0,000 0,0225592 0,04992041 ! phospholipid efflux GO:0033700 19 10 0,000 0,0225592 0,04987523 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0225592 0,04983014 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,0225592 0,04978512 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,0225592 0,04974019 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,0225592 0,04969534 ! pathogenesis GO:0009405 17 10 0,000 0,0225592 0,04965057 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0225592 0,04960588 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,0225592 0,04956127 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,0225592 0,04951674 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,0225592 0,04947229 ! endoderm development GO:0007492 18 10 0,000 0,0225592 0,04942792 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,0225592 0,04938363 ! arginine catabolic process GO:0006527 17 10 0,000 0,0225592 0,04933942 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0225592 0,04929529 ! proline metabolic process GO:0006560 13 10 0,000 0,0225592 0,04925123 ! phosphagen metabolic process GO:0006599 17 10 0,000 0,0225592 0,04920726 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,0225592 0,04916336 ! V(D)J recombination GO:0033151 34 10 0,000 0,0225592 0,04911955 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,0225592 0,04907581 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,0225592 0,04903215 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,0225592 0,04898856 ! B cell proliferation GO:0042100 19 10 0,000 0,0225592 0,04894505 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,0225592 0,04890163 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,0225592 0,04885827 ! multicellular organism growth GO:0035264 19 10 0,000 0,0225592 0,048815 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,0225592 0,0487718 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,0225592 0,04872868 ! ruffle organization GO:0031529 17 10 0,000 0,0225592 0,04868563 ! epithelial cell development GO:0002064 21 10 0,000 0,0225592 0,04864266 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,0225592 0,04859976 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0225592 0,04855694 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,0225592 0,0485142 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,0225592 0,04847153 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,0225592 0,04842894 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,0225592 0,04838642 ! motor axon guidance GO:0008045 22 10 0,000 0,0225592 0,04834398 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0225592 0,04830161 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0225592 0,04825931 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0225592 0,04821709 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,0225592 0,04817494 ! segment specification GO:0007379 15 10 0,000 0,0225592 0,04813287 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,0225592 0,04809087 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,0225592 0,04804894 ! blastoderm segmentation GO:0007350 19 10 0,000 0,0225592 0,04800708 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,0225592 0,0479653 ! response to dsRNA GO:0043331 23 10 0,000 0,0225592 0,04792359 ! DNA ligation GO:0006266 18 10 0,000 0,0225592 0,04788196 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,0225592 0,04784039 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0225592 0,0477989 ! melanosome localization GO:0032400 16 10 0,000 0,0225592 0,04775748 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,0225592 0,04771613 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,0225592 0,04767485 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,0225592 0,04763365 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0225592 0,04759251 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,0225592 0,04755145 ! induction of an organ GO:0001759 17 10 0,000 0,0225592 0,04751046 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,0225592 0,04746954 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,0225592 0,04742868 ! protein sumoylation GO:0016925 17 10 0,000 0,0225592 0,0473879 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0225592 0,04734719 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0225592 0,04730655 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0225592 0,04726598 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,0225592 0,04722548 ! salivary gland development GO:0007431 28 10 0,000 0,0225592 0,04718504 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,0225592 0,04714468 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,0225592 0,04710439 ! midbrain development GO:0030901 14 10 0,000 0,0225592 0,04706416 ! musculoskeletal movement GO:0050881 16 10 0,000 0,0225592 0,047024 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,0225592 0,04698391 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,0225592 0,04694389 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,0225592 0,04690394 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,0225592 0,04686406 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,0225592 0,04682424 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0225592 0,04678449 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0225592 0,04674481 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,0225592 0,0467052 ! detection of calcium ion GO:0005513 24 10 0,000 0,0225592 0,04666565 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0225592 0,04662617 ! blastocyst formation GO:0001825 18 10 0,000 0,0225592 0,04658676 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,0225592 0,04654741 ! cerebellar cortex development GO:0021695 16 10 0,000 0,0225592 0,04650813 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,0225592 0,04646891 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0225592 0,04642977 ! response to nicotine GO:0035094 20 10 0,000 0,0225592 0,04639068 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,0225592 0,04635167 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02478729 0,05088684 ! respiratory burst GO:0045730 17 11 0,000 0,02478729 0,05084411 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02478729 0,05080146 ! neuron fate specification GO:0048665 18 11 0,000 0,02478729 0,05075888 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02478729 0,05071636 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02478729 0,05067392 ! thyroid gland development GO:0030878 26 11 0,000 0,02478729 0,05063155 ! synapsis GO:0007129 14 11 0,000 0,02478729 0,05058926 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02478729 0,05054703 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02478729 0,05050487 ! response to pain GO:0048265 27 11 0,000 0,02478729 0,05046278 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02478729 0,05042077 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02478729 0,05037882 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02478729 0,05033694 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,02478729 0,05029513 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02478729 0,05025339 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02478729 0,05021172 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02478729 0,05017012 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02478729 0,05012859 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02478729 0,05008713 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02478729 0,05004573 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02478729 0,05000441 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02478729 0,04996315 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02478729 0,04992196 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02478729 0,04988084 ! UV protection GO:0009650 20 11 0,000 0,02478729 0,04983979 ! adult heart development GO:0007512 16 11 0,000 0,02478729 0,0497988 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02478729 0,04975788 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02478729 0,04971703 ! macroautophagy GO:0016236 19 11 0,000 0,02478729 0,04967624 ! temperature homeostasis GO:0001659 18 11 0,000 0,02478729 0,04963552 ! behavioral fear response GO:0001662 27 11 0,000 0,02478729 0,04959487 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02478729 0,04955429 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02478729 0,04951377 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02478729 0,04947332 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02478729 0,04943293 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02478729 0,04939261 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02478729 0,04935235 ! regulation of organ growth GO:0046620 14 11 0,000 0,02478729 0,04931217 ! pigment granule localization GO:0051875 20 11 0,000 0,02478729 0,04927204 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02478729 0,04923198 ! vasoconstriction GO:0042310 20 11 0,000 0,02478729 0,04919199 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02478729 0,04915206 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02478729 0,0491122 ! embryonic axis specification GO:0000578 19 11 0,000 0,02478729 0,0490724 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02478729 0,04903266 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02478729 0,04899299 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02478729 0,04895339 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02478729 0,04891384 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02478729 0,04887437 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02478729 0,04883495 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02478729 0,0487956 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02478729 0,04875631 ! prophase GO:0051324 17 11 0,000 0,02478729 0,04871709 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02478729 0,04867793 ! nucleosome positioning GO:0016584 15 11 0,000 0,02478729 0,04863883 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02478729 0,04859979 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02478729 0,04856082 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02478729 0,04852191 ! apical protein localization GO:0045176 18 11 0,000 0,02478729 0,04848306 ! acid secretion GO:0046717 20 11 0,000 0,02478729 0,04844427 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02478729 0,04840555 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02478729 0,04836688 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02478729 0,04832828 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02478729 0,04828974 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02478729 0,04825127 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02478729 0,04821285 ! cholesterol efflux GO:0033344 21 11 0,000 0,02478729 0,04817449 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02478729 0,0481362 ! oocyte development GO:0048599 20 11 0,000 0,02478729 0,04809797 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02478729 0,04805979 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02478729 0,04802168 ! embryonic gut development GO:0048566 19 11 0,000 0,02478729 0,04798363 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02478729 0,04794564 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02478729 0,0479077 ! activation of innate immune response GO:0002218 16 11 0,000 0,02478729 0,04786983 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02478729 0,04783202 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02478729 0,04779427 ! lysogeny GO:0030069 22 11 0,000 0,02478729 0,04775658 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02478729 0,04771894 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02478729 0,04768137 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02478729 0,04764385 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02478729 0,0476064 ! nucleus localization GO:0051647 22 11 0,000 0,02478729 0,047569 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02701035 0,05179458 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02701035 0,05175395 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02701035 0,05171339 ! virus-host interaction GO:0019048 30 12 0,000 0,02701035 0,0516729 ! mating GO:0007618 17 12 0,000 0,02701035 0,05163247 ! protein complex disassembly GO:0043241 28 12 0,000 0,02701035 0,0515921 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02701035 0,05155179 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02701035 0,05151155 ! hippocampus development GO:0021766 29 12 0,000 0,02701035 0,05147137 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,02701035 0,05143125 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02701035 0,05139119 ! T cell proliferation GO:0042098 32 12 0,000 0,02701035 0,0513512 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02701035 0,05131127 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02701035 0,0512714 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02701035 0,05123159 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02701035 0,05119185 ! drug transport GO:0015893 16 12 0,000 0,02701035 0,05115216 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02701035 0,05111254 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02701035 0,05107298 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02701035 0,05103348 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02701035 0,05099404 ! focal adhesion formation GO:0048041 37 12 0,000 0,02701035 0,05095466 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02701035 0,05091535 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02701035 0,05087609 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02701035 0,0508369 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02701035 0,05079776 ! lipid digestion GO:0044241 21 12 0,000 0,02701035 0,05075869 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02701035 0,05071967 ! entry into host cell GO:0030260 34 12 0,000 0,02701035 0,05068071 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02701035 0,05064182 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02701035 0,05060298 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02701035 0,05056421 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02701035 0,05052549 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02701035 0,05048683 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02701035 0,05044823 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02701035 0,0504097 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02701035 0,05037121 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02701035 0,05033279 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02701035 0,05029443 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02701035 0,05025612 ! cranial nerve development GO:0021545 23 12 0,000 0,02701035 0,05021788 ! fucose catabolic process GO:0019317 25 12 0,000 0,02701035 0,05017969 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02701035 0,05014156 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02701035 0,05010349 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02701035 0,05006547 ! T cell homeostasis GO:0043029 28 12 0,000 0,02701035 0,05002751 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02701035 0,04998961 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02701035 0,04995177 ! oocyte differentiation GO:0009994 21 12 0,000 0,02701035 0,04991399 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02701035 0,04987626 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02701035 0,04983859 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02701035 0,04980097 GO:0042130|negative regulation of T cell proliferation, ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02701035 0,04976342 ! defense response to fungus GO:0050832 15 12 0,000 0,02701035 0,04972592 ! developmental induction GO:0031128 22 12 0,000 0,02701035 0,04968847 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 0,000 0,02701035 0,04965108 ! response to cold GO:0009409 17 12 0,000 0,02701035 0,04961375 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02701035 0,04957648 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02701035 0,04953926 ! localization within membrane GO:0051668 26 12 0,000 0,02701035 0,04950209 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02922841 0,053527 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02922841 0,0534869 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02922841 0,05344687 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02922841 0,05340689 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02922841 0,05336698 ! peroxisomal transport GO:0043574 28 13 0,000 0,02922841 0,05332712 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02922841 0,05328732 ! cartilage condensation GO:0001502 22 13 0,000 0,02922841 0,05324759 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02922841 0,05320791 ! organelle fusion GO:0048284 36 13 0,000 0,02922841 0,05316829 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02922841 0,05312873 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02922841 0,05308923 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02922841 0,05304979 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02922841 0,0530104 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02922841 0,05297108 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02922841 0,05293181 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02922841 0,0528926 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02922841 0,05285345 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02922841 0,05281436 ! methionine metabolic process GO:0006555 31 13 0,000 0,02922841 0,05277533 ! plasma membrane organization GO:0007009 27 13 0,000 0,02922841 0,05273635 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02922841 0,05269743 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02922841 0,05265857 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02922841 0,05261976 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02922841 0,05258101 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02922841 0,05254232 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02922841 0,05250369 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02922841 0,05246511 ! exocrine system development GO:0035272 34 13 0,000 0,02922841 0,05242659 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02922841 0,05238813 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02922841 0,05234972 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02922841 0,05231137 ! L-glutamate transport GO:0015813 30 13 0,000 0,02922841 0,05227307 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02922841 0,05223483 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02922841 0,05219665 ! protein homotetramerization GO:0051289 24 13 0,000 0,02922841 0,05215852 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02922841 0,05212045 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02922841 0,05208243 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02922841 0,05204447 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02922841 0,05200657 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02922841 0,05196872 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02922841 0,05193092 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02922841 0,05189318 ! histone methylation GO:0016571 29 13 0,000 0,02922841 0,05185549 ! chromatin silencing GO:0006342 29 13 0,000 0,02922841 0,05181786 ! gland morphogenesis GO:0022612 31 13 0,000 0,02922841 0,05178029 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02922841 0,05174276 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02922841 0,0517053 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02922841 0,05166788 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02922841 0,05163052 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02922841 0,05159322 ! spleen development GO:0048536 24 13 0,000 0,02922841 0,05155597 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02922841 0,05151877 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02922841 0,05148163 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02922841 0,05144454 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02922841 0,0514075 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02922841 0,05137051 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02922841 0,05133358 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02922841 0,05129671 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02922841 0,05125988 ! insulin secretion GO:0030073 24 13 0,000 0,02922841 0,05122311 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02922841 0,05118639 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02922841 0,05114972 ! acrosome reaction GO:0007340 19 13 0,000 0,02922841 0,05111311 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02922841 0,05107655 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02922841 0,05104004 ! rRNA transcription GO:0009303 28 14 0,000 0,03144148 0,05486538 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03144148 0,05482622 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03144148 0,05478712 ! water transport GO:0006833 21 14 0,000 0,03144148 0,05474807 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,03144148 0,05470907 ! non-recombinational repair GO:0000726 29 14 0,000 0,03144148 0,05467013 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,03144148 0,05463125 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03144148 0,05459242 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,03144148 0,05455365 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03144148 0,05451493 ! lipid localization GO:0010876 32 14 0,000 0,03144148 0,05447627 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,03144148 0,05443766 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03144148 0,05439911 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03144148 0,05436061 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03144148 0,05432216 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03144148 0,05428377 ! arginine metabolic process GO:0006525 21 14 0,000 0,03144148 0,05424544 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03144148 0,05420716 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03144148 0,05416893 ! regulation of heart rate GO:0002027 25 14 0,000 0,03144148 0,05413075 ! fear response GO:0042596 34 14 0,000 0,03144148 0,05409263 ! organic alcohol transport GO:0015850 29 14 0,000 0,03144148 0,05405457 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03144148 0,05401655 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03144148 0,05397859 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03144148 0,05394069 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03144148 0,05390283 ! bone mineralization GO:0030282 18 14 0,000 0,03144148 0,05386503 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03144148 0,05382729 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03144148 0,05378959 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03144148 0,05375195 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03144148 0,05371436 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03144148 0,05367683 ! regulation of cellular pH GO:0030641 27 14 0,000 0,03144148 0,05363934 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03144148 0,05360191 ! ribosome assembly GO:0042255 18 14 0,000 0,03144148 0,05356453 ! cerebellum development GO:0021549 23 14 0,000 0,03144148 0,0535272 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03144148 0,05348993 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03144148 0,05345271 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03144148 0,05341553 ! response to gamma radiation GO:0010332 30 14 0,000 0,03144148 0,05337841 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03144148 0,05334135 ! NADP metabolic process GO:0006739 24 14 0,000 0,03144148 0,05330433 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03144148 0,05326736 ! oxygen transport GO:0015671 22 14 0,000 0,03144148 0,05323045 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03144148 0,05319359 ! male genitalia development GO:0030539 26 14 0,000 0,03144148 0,05315677 ! regulation of axon extension GO:0030516 43 14 0,000 0,03144148 0,05312001 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,03144148 0,0530833 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03144148 0,05304664 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,03144148 0,05301003 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03364957 0,05669372 ! lactation GO:0007595 30 15 0,000 0,03364957 0,05665464 ! reproductive cellular process GO:0048610 22 15 0,000 0,03364957 0,05661563 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03364957 0,05657666 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,03364957 0,05653775 ! superoxide anion generation GO:0042554 22 15 0,000 0,03364957 0,05649889 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,03364957 0,05646009 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,03364957 0,05642134 ! copper ion transport GO:0006825 22 15 0,000 0,03364957 0,05638264 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,03364957 0,056344 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,03364957 0,0563054 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,03364957 0,05626686 ! sulfate transport GO:0008272 27 15 0,000 0,03364957 0,05622838 ! response to cAMP GO:0051591 25 15 0,000 0,03364957 0,05618994 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,03364957 0,05615156 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,03364957 0,05611323 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,03364957 0,05607496 ! response to hexose stimulus GO:0009746 25 15 0,000 0,03364957 0,05603673 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,03364957 0,05599856 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,03364957 0,05596044 ! vesicle coating GO:0006901 38 15 0,000 0,03364957 0,05592237 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,03364957 0,05588436 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,03364957 0,05584639 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,03364957 0,05580848 ! regulation of exocytosis GO:0017157 26 15 0,000 0,03364957 0,05577062 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,03364957 0,05573281 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,03364957 0,05569505 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,03364957 0,05565734 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,03364957 0,05561968 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,03364957 0,05558208 ! regulation of vasodilation GO:0042312 27 15 0,000 0,03364957 0,05554452 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,03364957 0,05550701 ! histone deacetylation GO:0016575 24 15 0,000 0,03364957 0,05546956 ! water homeostasis GO:0030104 28 15 0,000 0,03364957 0,05543216 ! cofactor transport GO:0051181 30 15 0,000 0,03364957 0,0553948 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03364957 0,0553575 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,03364957 0,05532025 ! intestinal absorption GO:0050892 31 15 0,000 0,03364957 0,05528305 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03364957 0,05524589 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,03364957 0,05520879 ! heme biosynthetic process GO:0006783 33 15 0,000 0,03364957 0,05517174 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,03364957 0,05513473 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,03364957 0,05509778 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,03364957 0,05506088 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,03364957 0,05502402 ! actin filament polymerization GO:0030041 27 15 0,000 0,03364957 0,05498722 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,03364957 0,05495046 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03585268 0,05850908 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03585268 0,05847002 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03585268 0,05843102 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03585268 0,05839206 ! bone remodeling GO:0046849 28 16 0,000 0,03585268 0,05835316 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03585268 0,05831431 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03585268 0,05827551 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03585268 0,05823676 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03585268 0,05819807 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03585268 0,05815942 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03585268 0,05812083 ! startle response GO:0001964 28 16 0,000 0,03585268 0,05808229 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03585268 0,0580438 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03585268 0,05800536 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03585268 0,05796697 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03585268 0,05792863 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03585268 0,05789035 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03585268 0,05785211 ! pituitary gland development GO:0021983 30 16 0,000 0,03585268 0,05781392 ! response to osmotic stress GO:0006970 27 16 0,000 0,03585268 0,05777579 ! lysosomal transport GO:0007041 31 16 0,000 0,03585268 0,0577377 ! fructose metabolic process GO:0006000 25 16 0,000 0,03585268 0,05769967 ! L-amino acid transport GO:0015807 33 16 0,000 0,03585268 0,05766168 ! stem cell development GO:0048864 46 16 0,000 0,03585268 0,05762375 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03585268 0,05758586 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03585268 0,05754802 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03585268 0,05751024 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03585268 0,0574725 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03585268 0,05743482 ! axon cargo transport GO:0008088 46 16 0,000 0,03585268 0,05739718 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03585268 0,05735959 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03585268 0,05732205 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,03585268 0,05728456 ! neuron recognition GO:0008038 40 16 0,000 0,03585268 0,05724712 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03585268 0,05720973 ! tissue regeneration GO:0042246 27 16 0,000 0,03585268 0,05717238 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03585268 0,05713509 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03585268 0,05709784 ! biomineral formation GO:0031214 22 16 0,000 0,03585268 0,05706065 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03585268 0,0570235 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03585268 0,0569864 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03585268 0,05694935 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03585268 0,05691234 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03585268 0,05687539 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03585268 0,05683848 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03585268 0,05680162 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03585268 0,0567648 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03585268 0,05672804 ! peptide hormone processing GO:0016486 27 16 0,000 0,03585268 0,05669132 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03805083 0,06012819 ! metencephalon development GO:0022037 32 17 0,000 0,03805083 0,06008932 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03805083 0,0600505 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03805083 0,06001173 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03805083 0,05997302 ! signal complex assembly GO:0007172 47 17 0,000 0,03805083 0,05993435 ! filopodium assembly GO:0046847 42 17 0,000 0,03805083 0,05989573 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03805083 0,05985717 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03805083 0,05981865 ! glial cell development GO:0021782 28 17 0,000 0,03805083 0,05978018 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03805083 0,05974176 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03805083 0,05970339 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03805083 0,05966507 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,03805083 0,0596268 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03805083 0,05958858 ! myoblast differentiation GO:0045445 50 17 0,000 0,03805083 0,0595504 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03805083 0,05951228 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03805083 0,0594742 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03805083 0,05943617 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03805083 0,0593982 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03805083 0,05936027 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03805083 0,05932239 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03805083 0,05928455 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03805083 0,05924677 ! membrane budding GO:0006900 42 17 0,000 0,03805083 0,05920903 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03805083 0,05917134 ! regulation of protein binding GO:0043393 33 17 0,000 0,03805083 0,0591337 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03805083 0,05909611 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03805083 0,05905856 ! genitalia development GO:0048806 32 17 0,000 0,03805083 0,05902107 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03805083 0,05898362 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03805083 0,05894621 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03805083 0,05890886 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03805083 0,05887155 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03805083 0,05883429 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03805083 0,05879708 ! steroid catabolic process GO:0006706 34 17 0,000 0,03805083 0,05875991 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03805083 0,05872279 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03805083 0,05868572 ! gas transport GO:0015669 26 17 0,000 0,03805083 0,05864869 ! organic cation transport GO:0015695 32 17 0,000 0,03805083 0,05861171 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03805083 0,05857478 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03805083 0,0585379 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,04024403 0,06187298 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,04024403 0,06183407 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04024403 0,0617952 ! limbic system development GO:0021761 40 18 0,000 0,04024403 0,06175639 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04024403 0,06171762 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04024403 0,0616789 ! adult walking behavior GO:0007628 36 18 0,000 0,04024403 0,06164023 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04024403 0,06160161 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04024403 0,06156304 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04024403 0,06152451 ! centrosome cycle GO:0007098 26 18 0,000 0,04024403 0,06148603 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04024403 0,06144761 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,04024403 0,06140923 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,04024403 0,06137089 ! glycine metabolic process GO:0006544 30 18 0,000 0,04024403 0,06133261 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04024403 0,06129437 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,04024403 0,06125618 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,04024403 0,06121804 ! DNA integration GO:0015074 32 18 0,000 0,04024403 0,06117994 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,04024403 0,0611419 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,04024403 0,0611039 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,04024403 0,06106594 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04024403 0,06102804 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04024403 0,06099018 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04024403 0,06095237 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,04024403 0,0609146 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04024403 0,06087689 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,04024403 0,06083921 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,04024403 0,06080159 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04024403 0,06076401 ! detection of bacterium GO:0016045 22 18 0,000 0,04024403 0,06072648 ! nerve development GO:0021675 34 18 0,000 0,04024403 0,06068899 ! defense response to virus GO:0051607 43 18 0,000 0,04024403 0,06065155 ! microspike assembly GO:0030035 46 18 0,000 0,04024403 0,06061416 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04024403 0,06057681 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,04024403 0,06053951 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,04243229 0,06379206 ! positive regulation of translation GO:0045727 31 19 0,000 0,04243229 0,06375283 ! negative regulation of defense response GO:0031348 27 19 0,000 0,04243229 0,06371364 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,04243229 0,06367451 ! neuron maturation GO:0042551 46 19 0,000 0,04243229 0,06363542 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,04243229 0,06359638 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,04243229 0,06355739 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,04243229 0,06351844 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,04243229 0,06347954 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,04243229 0,0634407 ! inositol metabolic process GO:0006020 33 19 0,000 0,04243229 0,06340189 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04243229 0,06336314 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,04243229 0,06332443 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,04243229 0,06328577 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,04243229 0,06324716 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,04243229 0,0632086 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,04243229 0,06317008 ! cerebral cortex development GO:0021987 40 19 0,000 0,04243229 0,06313161 ! heme metabolic process GO:0042168 40 19 0,000 0,04243229 0,06309318 ! neuromuscular junction development GO:0007528 43 19 0,000 0,04243229 0,0630548 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,04243229 0,06301647 ! response to fungus GO:0009620 26 19 0,000 0,04243229 0,06297819 ! protein export from nucleus GO:0006611 40 19 0,000 0,04243229 0,06293995 ! heart process GO:0003015 32 19 0,000 0,04243229 0,06290176 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,04243229 0,06286361 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,04243229 0,06282551 ! visual learning GO:0008542 38 19 0,000 0,04243229 0,06278746 ! cellular pigmentation GO:0033059 37 19 0,000 0,04243229 0,06274945 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,04243229 0,06271149 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,04243229 0,06267358 ! vitamin transport GO:0051180 31 19 0,000 0,04243229 0,06263571 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,04243229 0,06259788 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,04243229 0,06256011 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,04243229 0,06252237 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,04243229 0,06248469 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,04243229 0,06244705 ! cilium assembly GO:0042384 38 19 0,000 0,04243229 0,06240945 ! peptide hormone secretion GO:0030072 32 19 0,000 0,04243229 0,0623719 ! protein secretion GO:0009306 45 20 0,000 0,04461563 0,06554178 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04461563 0,06550239 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04461563 0,06546305 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04461563 0,06542376 ! skin development GO:0043588 42 20 0,000 0,04461563 0,06538451 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04461563 0,06534531 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04461563 0,06530616 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04461563 0,06526706 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04461563 0,065228 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04461563 0,06518899 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04461563 0,06515002 ! response to alkaloid GO:0043279 38 20 0,000 0,04461563 0,0651111 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04461563 0,06507223 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,04461563 0,0650334 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,04461563 0,06499462 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04461563 0,06495589 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04461563 0,0649172 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04461563 0,06487856 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,04461563 0,06483997 ! body fluid secretion GO:0007589 33 20 0,000 0,04461563 0,06480142 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04461563 0,06476291 ! peptide secretion GO:0002790 38 20 0,000 0,04461563 0,06472446 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04461563 0,06468604 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,04461563 0,06464768 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04461563 0,06460936 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04461563 0,06457108 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04461563 0,06453285 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04461563 0,06449467 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04461563 0,06445653 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04461563 0,06441843 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04461563 0,06438038 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04461563 0,06434238 ! regulation of glucose import GO:0046324 30 20 0,000 0,04461563 0,06430442 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04461563 0,0642665 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04461563 0,06422863 ! negative regulation of translation GO:0017148 32 20 0,000 0,04461563 0,0641908 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04461563 0,06415302 ! regulation of cell killing GO:0031341 46 21 0,000 0,04679405 0,0672458 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04679405 0,06720627 ! hormone secretion GO:0046879 39 21 0,000 0,04679405 0,06716678 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04679405 0,06712734 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04679405 0,06708795 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04679405 0,0670486 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04679405 0,0670093 ! ovarian follicle development GO:0001541 39 21 0,000 0,04679405 0,06697004 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04679405 0,06693083 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,04679405 0,06689167 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04679405 0,06685255 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04679405 0,06681348 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04679405 0,06677445 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04679405 0,06673547 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04679405 0,06669653 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,04679405 0,06665764 ! sensory perception of pain GO:0019233 33 21 0,000 0,04679405 0,0666188 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04679405 0,06658 ! diencephalon development GO:0021536 36 21 0,000 0,04679405 0,06654125 ! collagen fibril organization GO:0030199 62 21 0,000 0,04679405 0,06650254 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04679405 0,06646387 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04679405 0,06642525 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04679405 0,06638668 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04679405 0,06634815 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,04679405 0,06630966 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04679405 0,06627122 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04679405 0,06623283 ! actin filament-based movement GO:0030048 47 21 0,000 0,04679405 0,06619448 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,04679405 0,06615617 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04896756 0,06918898 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04896756 0,06914899 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04896756 0,06910904 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04896756 0,06906914 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04896756 0,06902929 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04896756 0,06898948 ! microtubule-based transport GO:0010970 59 22 0,000 0,04896756 0,06894971 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04896756 0,06890999 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04896756 0,06887032 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,04896756 0,0688307 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,04896756 0,06879112 ! vacuolar transport GO:0007034 41 22 0,000 0,04896756 0,06875158 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04896756 0,06871209 ! fucose metabolic process GO:0006004 44 22 0,000 0,04896756 0,06867265 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04896756 0,06863325 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04896756 0,06859389 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04896756 0,06855459 ! ureteric bud development GO:0001657 50 22 0,000 0,04896756 0,06851532 ! cell aging GO:0007569 48 22 0,000 0,04896756 0,0684761 ! stem cell differentiation GO:0048863 57 22 0,000 0,04896756 0,06843693 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04896756 0,0683978 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04896756 0,06835871 ! cytolysis GO:0019835 27 22 0,000 0,04896756 0,06831968 ! renal system process GO:0003014 42 22 0,000 0,04896756 0,06828068 ! vasodilation GO:0042311 40 22 0,000 0,04896756 0,06824173 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04896756 0,06820282 ! G1 phase GO:0051318 44 22 0,000 0,04896756 0,06816396 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04896756 0,06812514 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04896756 0,06808637 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04896756 0,06804764 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04896756 0,06800895 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04896756 0,06797031 ! sarcomere organization GO:0045214 32 22 0,000 0,04896756 0,06793172 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04896756 0,06789316 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04896756 0,06785465 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04896756 0,06781619 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04896756 0,06777776 ! gut development GO:0048565 44 22 0,000 0,04896756 0,06773938 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04896756 0,06770105 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04896756 0,06766276 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04896756 0,06762451 ! protein stabilization GO:0050821 41 22 0,000 0,04896756 0,0675863 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,05113618 0,07053963 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,05113618 0,07049982 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,05113618 0,07046006 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,05113618 0,07042034 ! gluconeogenesis GO:0006094 38 23 0,000 0,05113618 0,07038067 ! glycerol metabolic process GO:0006071 40 23 0,000 0,05113618 0,07034104 ! viral genome replication GO:0019079 44 23 0,000 0,05113618 0,07030145 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,05113618 0,07026191 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,05113618 0,07022242 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,05113618 0,07018297 ! regeneration GO:0031099 42 23 0,000 0,05113618 0,07014356 ! axis specification GO:0009798 43 23 0,000 0,05113618 0,0701042 ! visual behavior GO:0007632 46 23 0,000 0,05113618 0,07006488 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,05113618 0,07002561 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,05113618 0,06998638 ! response to ethanol GO:0045471 47 23 0,000 0,05113618 0,06994719 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,05113618 0,06990805 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,05113618 0,06986895 ! peroxisome organization GO:0007031 43 23 0,000 0,05113618 0,0698299 ! lysosome organization GO:0007040 47 23 0,000 0,05113618 0,06979088 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,05113618 0,06975192 ! vesicle targeting GO:0006903 49 23 0,000 0,05113618 0,06971299 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,05113618 0,06967411 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,05113618 0,06963528 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,05113618 0,06959648 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,05113618 0,06955773 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,05113618 0,06951902 ! DNA modification GO:0006304 36 23 0,000 0,05113618 0,06948036 ! fatty acid transport GO:0015908 47 23 0,000 0,05113618 0,06944174 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,05113618 0,06940316 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,05113618 0,06936462 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,05113618 0,06932613 ! hormone transport GO:0009914 41 23 0,000 0,05113618 0,06928768 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,05113618 0,06924927 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,05113618 0,06921091 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,05113618 0,06917258 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,05329991 0,07205959 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,05329991 0,07201974 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,05329991 0,07197992 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,05329991 0,07194016 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,05329991 0,07190043 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,05329991 0,07186075 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,05329991 0,07182112 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,05329991 0,07178152 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,05329991 0,07174197 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,05329991 0,07170247 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,05329991 0,07166301 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,05329991 0,07162359 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,05329991 0,07158421 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,05329991 0,07154488 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,05329991 0,07150559 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,05329991 0,07146635 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,05329991 0,07142714 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,05329991 0,07138798 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,05329991 0,07134887 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,05329991 0,07130979 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,05329991 0,07127076 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,05329991 0,07123177 ! membrane depolarization GO:0051899 45 24 0,000 0,05329991 0,07119283 ! pallium development GO:0021543 56 24 0,000 0,05329991 0,07115393 ! oogenesis GO:0048477 44 24 0,000 0,05329991 0,07111506 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,05329991 0,07107625 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,05329991 0,07103747 ! platelet activation GO:0030168 41 24 0,000 0,05329991 0,07099874 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,05329991 0,07096005 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,05329991 0,0709214 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,05329991 0,07088279 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,05329991 0,07084422 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,05329991 0,0708057 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,05329991 0,07076722 ! regulation of amine transport GO:0051952 41 24 0,000 0,05329991 0,07072878 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,05329991 0,07069038 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,05545877 0,07351372 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,05545877 0,07347385 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,05545877 0,07343403 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,05545877 0,07339425 ! phototransduction GO:0007602 37 25 0,000 0,05545877 0,07335451 ! keratinization GO:0031424 37 25 0,000 0,05545877 0,07331482 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,05545877 0,07327516 ! vacuole organization GO:0007033 49 25 0,000 0,05545877 0,07323556 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,05545877 0,07319599 ! receptor metabolic process GO:0043112 53 25 0,000 0,05545877 0,07315647 ! chromosome condensation GO:0030261 48 25 0,000 0,05545877 0,07311699 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,05545877 0,07307755 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,05545877 0,07303816 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,05545877 0,0729988 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,05545877 0,07295949 ! immunoglobulin production GO:0002377 62 25 0,000 0,05545877 0,07292023 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,05545877 0,072881 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,05545877 0,07284182 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,05545877 0,07280268 ! liver development GO:0001889 55 25 0,000 0,05545877 0,07276358 ! protein tetramerization GO:0051262 57 25 0,000 0,05545877 0,07272452 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05761277 0,07550858 ! myelination GO:0042552 50 26 0,000 0,05761277 0,07546809 ! initiation of viral infection GO:0019059 60 26 0,000 0,05761277 0,07542765 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05761277 0,07538725 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05761277 0,07534689 ! molting cycle process GO:0022404 52 26 0,000 0,05761277 0,07530658 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05761277 0,07526631 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,05761277 0,07522608 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05761277 0,07518589 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05761277 0,07514575 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,05761277 0,07510565 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05761277 0,0750656 ! digestive system process GO:0022600 49 26 0,000 0,05761277 0,07502558 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05761277 0,07498561 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,05761277 0,07494568 ! osteoblast differentiation GO:0001649 63 26 0,000 0,05761277 0,0749058 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05761277 0,07486595 ! negative regulation of cell development GO:0010721 83 26 0,000 0,05761277 0,07482615 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05761277 0,07478639 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05761277 0,07474668 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05761277 0,074707 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05761277 0,07466737 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,05761277 0,07462778 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,05761277 0,07458823 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05761277 0,07454873 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05761277 0,07450926 ! blastocyst development GO:0001824 50 26 0,000 0,05761277 0,07446984 ! telomere organization GO:0032200 46 26 0,000 0,05761277 0,07443046 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05761277 0,07439112 ! neural tube closure GO:0001843 58 26 0,000 0,05761277 0,07435182 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05761277 0,07431256 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05761277 0,07427335 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05761277 0,07423417 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,05976192 0,07696276 ! embryonic pattern specification GO:0009880 49 27 0,000 0,05976192 0,07692221 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,05976192 0,07688171 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,05976192 0,07684124 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,05976192 0,07680082 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,05976192 0,07676044 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,05976192 0,0767201 ! iron ion transport GO:0006826 65 27 0,000 0,05976192 0,07667981 ! superoxide metabolic process GO:0006801 41 27 0,000 0,05976192 0,07663956 ! tube lumen formation GO:0035148 59 27 0,000 0,05976192 0,07659935 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,05976192 0,07655918 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,05976192 0,07651906 ! response to toxin GO:0009636 49 27 0,000 0,05976192 0,07647897 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,05976192 0,07643893 ! leukocyte proliferation GO:0070661 59 27 0,000 0,05976192 0,07639893 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,05976192 0,07635897 ! neuron fate commitment GO:0048663 52 28 0,000 0,06190622 0,07905745 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,06190622 0,07901614 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,06190622 0,07897488 ! vesicle docking GO:0048278 55 28 0,000 0,06190622 0,07893366 ! circadian rhythm GO:0007623 56 28 0,000 0,06190622 0,07889249 ! dendrite development GO:0016358 67 28 0,000 0,06190622 0,07885135 ! fat cell differentiation GO:0045444 57 28 0,000 0,06190622 0,07881026 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,06190622 0,07876922 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,06190622 0,07872821 ! base-excision repair GO:0006284 41 28 0,000 0,06190622 0,07868725 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,06190622 0,07864633 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,06190622 0,07860546 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,06190622 0,07856462 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,06190622 0,07852383 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,06190622 0,07848308 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,06190622 0,07844237 ! glutathione metabolic process GO:0006749 42 28 0,000 0,06190622 0,07840171 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,06190622 0,07836109 ! lipid oxidation GO:0034440 48 28 0,000 0,06190622 0,07832051 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,06190622 0,07827997 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,06190622 0,07823947 ! translational initiation GO:0006413 66 29 0,000 0,0640457 0,08090157 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,0640457 0,08085976 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,0640457 0,08081799 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,0640457 0,08077627 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,0640457 0,08073459 ! primary neural tube formation GO:0014020 61 29 0,000 0,0640457 0,08069295 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,0640457 0,08065136 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,0640457 0,08060981 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,0640457 0,0805683 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,0640457 0,08052683 ! synaptogenesis GO:0007416 46 29 0,000 0,0640457 0,08048541 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,0640457 0,08044403 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,0640457 0,08040269 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,0640457 0,08036139 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,0640457 0,08032014 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,06618035 0,08295464 ! phenol metabolic process GO:0018958 56 30 0,000 0,06618035 0,0829121 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,06618035 0,0828696 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,06618035 0,08282715 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,06618035 0,08278474 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,06618035 0,08274237 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,06618035 0,08270005 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,06618035 0,08265777 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,06618035 0,08261553 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,06618035 0,08257334 ! myofibril assembly GO:0030239 50 30 0,000 0,06618035 0,08253119 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,06618035 0,08248908 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,06618035 0,08244702 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,06618035 0,08240499 ! cell fate determination GO:0001709 64 30 0,000 0,06618035 0,08236301 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,06618035 0,08232108 ! phospholipid transport GO:0015914 65 30 0,000 0,06618035 0,08227918 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,06618035 0,08223733 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,06618035 0,08219552 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,06618035 0,08215376 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,06618035 0,08211204 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,06618035 0,08207035 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,06618035 0,08202872 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,0683102 0,08462567 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,0683102 0,08458277 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,0683102 0,08453993 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,0683102 0,08449712 ! regulation of innate immune response GO:0045088 57 31 0,000 0,0683102 0,08445436 ! ovulation cycle process GO:0022602 55 31 0,000 0,0683102 0,08441164 ! peptide transport GO:0015833 60 31 0,000 0,0683102 0,08436897 ! male gonad development GO:0008584 56 31 0,000 0,0683102 0,08432633 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,0683102 0,08428374 ! detection of light stimulus GO:0009583 44 31 0,000 0,0683102 0,0842412 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,0683102 0,0841987 ! natural killer cell activation GO:0030101 50 31 0,000 0,0683102 0,08415624 ! ensheathment of neurons GO:0007272 64 31 0,000 0,0683102 0,08411382 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,0683102 0,08407144 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,0683102 0,08402911 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,0683102 0,08398682 ! eye morphogenesis GO:0048592 65 31 0,000 0,0683102 0,08394457 ! response to heat GO:0009408 54 31 0,000 0,0683102 0,08390237 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,0683102 0,08386021 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,07043525 0,08642557 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,07043525 0,08638218 ! spindle organization GO:0007051 50 32 0,000 0,07043525 0,08633884 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,07043525 0,08629554 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,07043525 0,08625229 ! metanephros development GO:0001656 81 32 0,000 0,07043525 0,08620907 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,07043525 0,0861659 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,07043525 0,08612278 ! muscle cell development GO:0055001 52 32 0,000 0,07043525 0,08607969 ! mesoderm formation GO:0001707 73 32 0,000 0,07043525 0,08603665 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,07043525 0,08599366 ! ovulation cycle GO:0042698 57 32 0,000 0,07043525 0,0859507 ! peripheral nervous system development GO:0007422 68 32 0,000 0,07043525 0,08590779 ! BMP signaling pathway GO:0030509 71 32 0,000 0,07043525 0,08586492 ! hindbrain development GO:0030902 65 32 0,000 0,07043525 0,0858221 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,07043525 0,08577932 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,07043525 0,08573658 ! gene silencing GO:0016458 71 32 0,000 0,07043525 0,08569388 ! regulation of pH GO:0006885 56 33 0,000 0,07255551 0,08822952 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,07255551 0,08818563 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,07255551 0,08814177 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,07255551 0,08809797 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,07255551 0,0880542 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,07255551 0,08801048 ! response to ionizing radiation GO:0010212 74 33 0,000 0,07255551 0,0879668 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,07255551 0,08792317 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,07255551 0,08787958 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,07255551 0,08783603 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,07255551 0,08779253 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,07255551 0,08774906 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,07255551 0,08770565 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,07255551 0,08766227 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,07467099 0,09017362 ! glial cell differentiation GO:0010001 67 34 0,000 0,07467099 0,09012907 ! post-embryonic development GO:0009791 76 34 0,000 0,07467099 0,09008456 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,07467099 0,0900401 ! cholesterol transport GO:0030301 62 34 0,000 0,07467099 0,08999568 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,07467099 0,0899513 ! spliceosome assembly GO:0000245 75 34 0,000 0,07467099 0,08990697 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,07467099 0,08986268 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,07467099 0,08981843 ! formation of primary germ layer GO:0001704 76 34 0,000 0,07467099 0,08977423 ! cell fate specification GO:0001708 56 34 0,000 0,07467099 0,08973007 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,07467099 0,08968596 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,07467099 0,08964189 ! adult locomotory behavior GO:0008344 62 34 0,000 0,07467099 0,08959786 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,07678171 0,09208529 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,07678171 0,0920401 ! negative regulation of secretion GO:0051048 68 35 0,000 0,07678171 0,09199496 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,07678171 0,09194987 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,07678171 0,09190482 ! membrane docking GO:0022406 69 35 0,000 0,07678171 0,09185981 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,07678171 0,09181484 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,07678171 0,09176993 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,07678171 0,09172505 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,07678171 0,09168022 ! ceramide metabolic process GO:0006672 72 35 0,000 0,07678171 0,09163543 ! telencephalon development GO:0021537 81 35 0,000 0,07678171 0,09159069 ! sterol transport GO:0015918 63 35 0,000 0,07678171 0,09154599 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,07678171 0,09150133 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,07678171 0,09145672 ! vesicle localization GO:0051648 70 35 0,000 0,07678171 0,09141215 ! regulation of muscle development GO:0048634 82 36 0,000 0,07888768 0,09387365 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,07888768 0,09382794 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,07888768 0,09378229 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,07888768 0,09373667 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,07888768 0,0936911 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,07888768 0,09364558 ! positive regulation of cell development GO:0010720 85 36 0,000 0,07888768 0,0936001 ! protein targeting to membrane GO:0006612 75 36 0,000 0,07888768 0,09355466 ! regulation of proteolysis GO:0030162 77 36 0,000 0,07888768 0,09350927 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,07888768 0,09346392 ! aerobic respiration GO:0009060 56 36 0,000 0,07888768 0,09341861 ! cytokine production GO:0001816 68 36 0,000 0,07888768 0,09337335 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,07888768 0,09332813 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,07888768 0,09328296 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,0809889 0,09572128 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,0809889 0,09567499 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,0809889 0,09562875 ! sister chromatid segregation GO:0000819 65 37 0,000 0,0809889 0,09558255 ! odontogenesis GO:0042476 74 37 0,000 0,0809889 0,0955364 ! actomyosin structure organization GO:0031032 68 37 0,000 0,0809889 0,09549029 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,0809889 0,09544422 ! female gonad development GO:0008585 71 37 0,000 0,0809889 0,09539821 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,0809889 0,09535223 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,0809889 0,0953063 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,0809889 0,09526041 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,0809889 0,09521457 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,08308538 0,09763232 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,08308538 0,09758538 ! meiosis I GO:0007127 74 38 0,000 0,08308538 0,09753849 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,08308538 0,09749164 ! organic anion transport GO:0015711 82 38 0,000 0,08308538 0,09744483 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,08308538 0,09739808 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,08308538 0,09735136 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,08308538 0,09730469 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,08308538 0,09725807 ! regulation of protein stability GO:0031647 77 38 0,000 0,08308538 0,09721149 ! spermatid development GO:0007286 69 38 0,000 0,08308538 0,09716495 ! pigment metabolic process GO:0042440 87 38 0,000 0,08308538 0,09711846 ! neural tube formation GO:0001841 79 38 0,000 0,08308538 0,09707202 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,08517714 0,09946834 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,08517714 0,09942081 ! negative regulation of binding GO:0051100 71 39 0,000 0,08517714 0,09937334 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,08517714 0,0993259 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,08517714 0,09927851 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,08517714 0,09923117 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,08517714 0,09918387 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,08517714 0,09913662 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,08517714 0,09908941 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,08726419 0,10146903 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,08726419 0,10142075 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,08726419 0,10137253 ! learning GO:0007612 82 40 0,000 0,08726419 0,10132435 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,08726419 0,10127621 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,08726419 0,10122812 ! lipid homeostasis GO:0055088 75 40 0,000 0,08726419 0,10118008 ! mismatch repair GO:0006298 58 40 0,000 0,08726419 0,10113208 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,08726419 0,10108413 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,08726419 0,10103622 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,08726419 0,10098836 ! RNA export from nucleus GO:0006405 61 41 0,000 0,08934654 0,10334924 ! mRNA catabolic process GO:0006402 79 41 0,000 0,08934654 0,10330033 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,08934654 0,10325146 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,08934654 0,10320264 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,08934654 0,10315387 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,08934654 0,10310515 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,08934654 0,10305647 ! gliogenesis GO:0042063 91 41 0,000 0,08934654 0,10300783 ! feeding behavior GO:0007631 69 41 0,000 0,08934654 0,10295924 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,08934654 0,1029107 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,08934654 0,1028622 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,08934654 0,10281375 ! spermatid differentiation GO:0048515 73 41 0,000 0,08934654 0,10276535 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,08934654 0,10271699 ! RNA modification GO:0009451 64 41 0,000 0,08934654 0,10266867 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,09142419 0,10500672 ! ear morphogenesis GO:0042471 64 42 0,000 0,09142419 0,10495738 ! organic ether metabolic process GO:0018904 59 42 0,000 0,09142419 0,10490808 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,09142419 0,10485883 ! T cell differentiation GO:0030217 93 42 0,000 0,09142419 0,10480962 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,09142419 0,10476046 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,09142419 0,10471135 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,09142419 0,10466228 ! regulation of protein secretion GO:0050708 77 42 0,000 0,09142419 0,10461326 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,09142419 0,10456428 ! cytokinesis GO:0000910 84 42 0,000 0,09142419 0,10451535 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,09142419 0,10446646 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,09349716 0,10678521 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,09349716 0,10673531 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,09349716 0,10668546 ! regulation of tube size GO:0035150 76 43 0,000 0,09349716 0,10663565 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,09349716 0,10658589 ! glucose transport GO:0015758 66 43 0,000 0,09349716 0,10653618 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,09349716 0,10648651 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,09349716 0,10643689 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,09349716 0,10638732 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,09349716 0,10633779 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,09349716 0,10628831 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,09349716 0,10623887 ! ion transmembrane transport GO:0034220 79 43 0,000 0,09349716 0,10618948 ! neuron migration GO:0001764 85 43 0,000 0,09349716 0,10614014 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,09556546 0,10843773 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,09556546 0,10838739 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,09556546 0,10833709 ! hexose transport GO:0008645 68 44 0,000 0,09556546 0,10828684 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,09556546 0,10823664 ! striated muscle contraction GO:0006941 85 44 0,000 0,09556546 0,10818648 ! phagocytosis GO:0006909 105 44 0,000 0,09556546 0,10813637 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,09556546 0,10808631 ! double-strand break repair GO:0006302 85 44 0,000 0,09556546 0,10803629 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,0976291 0,11031818 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,0976291 0,11026718 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,0976291 0,11021622 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,0976291 0,11016531 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,0976291 0,11011445 ! biopolymer methylation GO:0043414 91 45 0,000 0,0976291 0,11006364 ! B cell differentiation GO:0030183 124 45 0,000 0,0976291 0,11001287 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,0976291 0,10996215 ! female gamete generation GO:0007292 71 45 0,000 0,0976291 0,10991147 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,0976291 0,10986085 ! polyol metabolic process GO:0019751 77 45 0,000 0,0976291 0,10981027 ! developmental growth GO:0048589 88 45 0,000 0,0976291 0,10975973 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,09968809 0,112023 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,09968809 0,1119715 ! glycolysis GO:0006096 71 46 0,000 0,09968809 0,11192004 ! leukocyte migration GO:0050900 75 46 0,000 0,09968809 0,11186863 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,09968809 0,11181727 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,09968809 0,11176595 ! cell growth GO:0016049 90 46 0,000 0,09968809 0,11171468 ! neural tube development GO:0021915 91 47 0,000 0,10174244 0,1139646 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,10174244 0,11391237 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,10379216 0,11615403 ! positive regulation of defense response GO:0031349 88 48 0,000 0,10379216 0,11610084 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,10379216 0,11604771 ! mitochondrial transport GO:0006839 94 48 0,000 0,10379216 0,11599462 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,10379216 0,11594158 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,10379216 0,11588859 ! endosome transport GO:0016197 127 48 0,000 0,10379216 0,11583565 ! male sex differentiation GO:0046661 93 48 0,000 0,10379216 0,11578276 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,10379216 0,11572992 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,10379216 0,11567712 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,10379216 0,11562437 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,10379216 0,11557167 ! methylation GO:0032259 97 48 0,000 0,10379216 0,11551902 ! response to calcium ion GO:0051592 94 49 0,000 0,10583726 0,11774154 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,10583726 0,11768795 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,10583726 0,11763441 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,10583726 0,11758091 ! protein homooligomerization GO:0051260 84 49 0,000 0,10583726 0,11752746 ! regulation of action potential GO:0001508 102 50 0,000 0,10787775 0,11973891 ! regulation of ion transport GO:0043269 86 50 0,000 0,10787775 0,11968453 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,10787775 0,1196302 ! endocrine system development GO:0035270 109 50 0,000 0,10787775 0,11957592 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,10787775 0,1195217 ! activation of caspase activity GO:0006919 95 50 0,000 0,10787775 0,11946752 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,10787775 0,11941338 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,10787775 0,1193593 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,10787775 0,11930527 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,10787775 0,11925128 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,10991364 0,12144687 ! viral infectious cycle GO:0019058 104 51 0,000 0,10991364 0,12139196 ! peptide metabolic process GO:0006518 80 51 0,000 0,10991364 0,12133711 ! response to temperature stimulus GO:0009266 84 51 0,000 0,10991364 0,1212823 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,10991364 0,12122755 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,10991364 0,12117284 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,11194494 0,12335656 ! Notch signaling pathway GO:0007219 111 52 0,000 0,11194494 0,12330094 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,11194494 0,12324538 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,11194494 0,12318986 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,11194494 0,12313439 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,11194494 0,12307898 ! excretion GO:0007588 87 52 0,000 0,11194494 0,12302361 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,11194494 0,1229683 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,11194494 0,12291303 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,11194494 0,12285781 ! amino acid activation GO:0043038 98 52 0,000 0,11194494 0,12280264 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,11397166 0,12496983 ! inner ear development GO:0048839 89 53 0,000 0,11397166 0,12491376 ! chromatin remodeling GO:0006338 122 53 0,000 0,11397166 0,12485775 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,11397166 0,12480178 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,11397166 0,12474587 ! vesicle organization GO:0016050 127 53 0,000 0,11397166 0,12469 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,11397166 0,12463419 ! synapse organization GO:0050808 102 53 0,000 0,11397166 0,12457842 ! regulation of translational initiation GO:0006446 87 54 0,000 0,11599382 0,12673207 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,11599382 0,12667541 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,11599382 0,12661881 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,11599382 0,12656226 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,11599382 0,12650576 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,11599382 0,12644931 ! membrane fusion GO:0006944 122 54 0,000 0,11599382 0,12639291 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,11599382 0,12633656 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,11599382 0,12628026 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,11599382 0,12622401 ! RNA catabolic process GO:0006401 103 55 0,000 0,11801142 0,12836237 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,11801142 0,12830525 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,11801142 0,12824817 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,11801142 0,12819115 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,11801142 0,12813417 ! cell maturation GO:0048469 107 55 0,000 0,11801142 0,12807725 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,11801142 0,12802038 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,11801142 0,12796355 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,12002446 0,13008863 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,12002446 0,13003094 ! glucose catabolic process GO:0006007 88 56 0,000 0,12002446 0,1299733 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,12002446 0,12991571 ! RNA elongation GO:0006354 90 56 0,000 0,12002446 0,12985818 ! chloride transport GO:0006821 102 57 0,000 0,12203297 0,1319728 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,12203297 0,1319144 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,12203297 0,13185606 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,12203297 0,13179777 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,12203297 0,13173953 ! regulation of actin filament length GO:0030832 118 58 0,000 0,12403696 0,13384377 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,12403696 0,13378467 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,12403696 0,13372563 ! aging GO:0007568 112 58 0,000 0,12403696 0,13366665 ! gastrulation GO:0007369 122 58 0,000 0,12403696 0,13360771 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,12403696 0,13354883 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,12403696 0,13348999 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,12403696 0,13343121 ! nuclear export GO:0051168 110 59 0,000 0,12603642 0,13552244 ! establishment of organelle localization GO:0051656 122 59 0,000 0,12603642 0,13546281 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,12803138 0,13754646 ! DNA catabolic process GO:0006308 94 60 0,000 0,12803138 0,137486 ! regulation of endocytosis GO:0030100 104 60 0,000 0,12803138 0,1374256 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,12803138 0,13736524 ! adult behavior GO:0030534 104 60 0,000 0,12803138 0,13730494 ! kidney development GO:0001822 133 60 0,000 0,12803138 0,13724469 ! positive regulation of secretion GO:0051047 110 61 0,000 0,13002184 0,13931726 ! regulation of cellular component size GO:0032535 125 61 0,000 0,13002184 0,13925618 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,13002184 0,13919516 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,13002184 0,13913419 ! regulation of heart contraction GO:0008016 123 61 0,000 0,13002184 0,13907327 ! camera-type eye development GO:0043010 126 61 0,000 0,13002184 0,13901241 ! proton transport GO:0015992 117 61 0,000 0,13002184 0,1389516 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,13002184 0,13889084 ! viral reproductive process GO:0022415 132 62 0,000 0,13200781 0,14095065 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,13200781 0,14088907 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,13200781 0,14082754 ! tRNA processing GO:0008033 102 62 0,000 0,13200781 0,14076607 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,1339893 0,1428167 ! regulation of mitosis GO:0007088 112 63 0,000 0,1339893 0,14275441 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,1339893 0,14269218 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,1339893 0,14263001 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,1339893 0,14256789 ! hydrogen transport GO:0006818 121 64 0,000 0,13596633 0,14460851 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,13596633 0,14454558 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,13596633 0,14448271 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,1379389 0,1465151 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,1379389 0,14645142 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,1379389 0,1463878 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,1379389 0,14632424 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,1379389 0,14626073 ! ear development GO:0043583 114 66 0,000 0,13990702 0,14828323 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,13990702 0,14821893 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,13990702 0,14815468 ! gonad development GO:0008406 115 66 0,000 0,13990702 0,14809049 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,13990702 0,14802635 ! activation of MAPK activity GO:0000187 124 67 0,000 0,1418707 0,15003901 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,1418707 0,14997409 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,1418707 0,14990922 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,1418707 0,14984441 ! secondary metabolic process GO:0019748 125 67 0,000 0,1418707 0,14977966 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,1418707 0,14971496 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,14382996 0,151717 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,14382996 0,15165152 ! hexose catabolic process GO:0019320 113 68 0,000 0,14382996 0,1515861 ! extracellular matrix organization GO:0030198 146 68 0,000 0,14382996 0,15152073 ! detection of external stimulus GO:0009581 102 68 0,000 0,14382996 0,15145542 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,14382996 0,15139017 ! viral reproduction GO:0016032 142 68 0,000 0,14382996 0,15132497 ! regulation of lipase activity GO:0060191 137 68 0,000 0,14382996 0,15125983 ! cell projection assembly GO:0030031 138 68 0,000 0,14382996 0,15119474 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,14578479 0,15318376 ! urogenital system development GO:0001655 149 69 0,000 0,14578479 0,1531179 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,14578479 0,1530521 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,14578479 0,15298636 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,14578479 0,15292067 ! developmental maturation GO:0021700 128 69 0,000 0,14578479 0,15285504 ! cell redox homeostasis GO:0045454 114 70 0,000 0,14773522 0,15483361 ! germ cell development GO:0007281 133 70 0,000 0,14773522 0,15476721 ! activation of immune response GO:0002253 120 70 0,000 0,14773522 0,15470088 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,14773522 0,15463459 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,14968125 0,15660441 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,14968125 0,15653737 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,14968125 0,15647039 ! appendage morphogenesis GO:0035107 150 72 0,000 0,15162289 0,1584323 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,15162289 0,15836457 ! actin filament organization GO:0007015 167 72 0,000 0,15162289 0,15829689 ! B cell activation GO:0042113 179 72 0,000 0,15162289 0,15822927 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,15162289 0,15816171 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,15162289 0,1580942 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,15162289 0,15802676 ! appendage development GO:0048736 151 73 0,000 0,15356015 0,15997759 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,15356015 0,1599094 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,15356015 0,15984127 ! regulation of immune effector process GO:0002697 156 73 0,000 0,15356015 0,15977319 ! amino acid transport GO:0006865 148 74 0,000 0,15549304 0,16171541 ! regulation of caspase activity GO:0043281 136 74 0,000 0,15549304 0,1616466 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,15549304 0,16157784 ! transition metal ion transport GO:0000041 143 75 0,000 0,15742158 0,16351229 ! reproductive structure development GO:0048608 131 75 0,000 0,15742158 0,1634428 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,15742158 0,16337337 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,15742158 0,163304 ! eye development GO:0001654 155 75 0,000 0,15742158 0,16323468 ! axon guidance GO:0007411 162 75 0,000 0,15742158 0,16316543 ! rhythmic process GO:0048511 142 75 0,000 0,15742158 0,16309623 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,15934576 0,16501979 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,15934576 0,16494987 ! regulation of blood pressure GO:0008217 134 76 0,000 0,15934576 0,16488 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,15934576 0,1648102 ! amine catabolic process GO:0009310 136 77 0,000 0,1612656 0,16672529 ! neurotransmitter transport GO:0006836 142 77 0,000 0,1612656 0,16665477 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,1612656 0,1665843 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,1612656 0,16651389 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,1612656 0,16644354 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,1612656 0,16637326 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,16318112 0,16827837 ! antigen processing and presentation GO:0019882 117 78 0,000 0,16318112 0,16820737 ! blood coagulation GO:0007596 151 79 0,000 0,16509231 0,17010565 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,16509231 0,17003394 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,16509231 0,16996229 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,16509231 0,16989069 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,16509231 0,16981916 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,16699919 0,17170834 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,16699919 0,1716361 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,16699919 0,17156393 ! muscle cell differentiation GO:0042692 178 81 0,000 0,16890177 0,17344557 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,16890177 0,1733727 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,16890177 0,17329988 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,17080005 0,17517403 ! protein import into nucleus GO:0006606 174 82 0,000 0,17080005 0,17510052 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,17269406 0,17696795 ! exocytosis GO:0006887 153 83 0,000 0,17269406 0,17689375 ! response to drug GO:0042493 149 83 0,000 0,17269406 0,17681961 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,17269406 0,17674553 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,17269406 0,17667152 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,17269406 0,17659757 ! nuclear import GO:0051170 177 83 0,000 0,17269406 0,17652368 ! inorganic anion transport GO:0015698 156 83 0,000 0,17269406 0,17644985 ! response to metal ion GO:0010038 158 84 0,000 0,17458379 0,1783061 ! T cell activation GO:0042110 189 84 0,000 0,17458379 0,17823159 ! hemostasis GO:0007599 165 85 0,000 0,17646926 0,1800812 ! negative regulation of transport GO:0051051 164 85 0,000 0,17646926 0,18000601 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,17646926 0,17993089 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,17646926 0,17985582 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,17646926 0,17978082 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,17646926 0,17970588 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,17835047 0,18154592 ! regulation of lyase activity GO:0051339 169 86 0,000 0,17835047 0,18147031 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,18022744 0,18330377 ! mitochondrion organization GO:0007005 159 87 0,000 0,18022744 0,18322749 ! alcohol catabolic process GO:0046164 142 87 0,000 0,18022744 0,18315127 ! cellular respiration GO:0045333 143 88 0,000 0,18210018 0,18497744 ! amine biosynthetic process GO:0009309 146 88 0,000 0,18210018 0,18490056 ! sensory perception of smell GO:0007608 117 88 0,000 0,18210018 0,18482374 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,18210018 0,18474698 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,18396869 0,18656518 ! tube morphogenesis GO:0035239 194 89 0,000 0,18396869 0,18648776 ! cellular defense response GO:0006968 123 89 0,000 0,18396869 0,18641041 ! protein localization in nucleus GO:0034504 192 89 0,000 0,18396869 0,18633313 ! regulation of neurological system process GO:0031644 175 89 0,000 0,18396869 0,18625591 ! response to inorganic substance GO:0010035 173 90 0,000 0,18583298 0,18806544 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,18583298 0,18798757 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,18583298 0,18790976 ! response to unfolded protein GO:0006986 139 90 0,000 0,18583298 0,18783201 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,18583298 0,18775433 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,18769307 0,18955526 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 220 91 0,000 0,18769307 0,18947693 ! defense response to bacterium GO:0042742 112 91 0,000 0,18769307 0,18939867 ! amine transport GO:0015837 181 93 0,000 0,19140066 0,19306021 ! vitamin metabolic process GO:0006766 153 93 0,000 0,19140066 0,19298053 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,19324819 0,19476292 ! female pregnancy GO:0007565 166 94 0,000 0,19324819 0,1946826 ! sterol metabolic process GO:0016125 166 94 0,000 0,19324819 0,19460236 ! regulation of membrane potential GO:0042391 179 94 0,000 0,19324819 0,19452217 ! regulation of defense response GO:0031347 171 95 0,000 0,19509154 0,1962968 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,19509154 0,19621599 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,19509154 0,19613524 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,19509154 0,19605456 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,19509154 0,19597394 ! sex differentiation GO:0007548 171 96 0,000 0,19693073 0,19774015 ! response to protein stimulus GO:0051789 158 96 0,000 0,19693073 0,19765891 ! regulation of T cell activation GO:0050863 175 96 0,000 0,19693073 0,19757773 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,19876578 0,19933694 ! transcription initiation GO:0006352 171 97 0,000 0,19876578 0,19925515 ! leukocyte differentiation GO:0002521 232 98 0,000 0,20059668 0,20100807 ! forebrain development GO:0030900 210 98 0,000 0,20059668 0,20092566 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,20059668 0,20084331 ! mRNA transport GO:0051028 185 100 0,000 0,20424609 0,20441344 ! positive regulation of immune response GO:0050778 175 100 0,000 0,20424609 0,20432973 ! hormone metabolic process GO:0042445 171 100 0,000 0,20424609 0,20424609