pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1064-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! myeloid leukocyte differentiation GO:0002573 40 23 4,000 7,263E-09 1,747E-05 ! regulation of DNA metabolic process GO:0051052 178 97 6,000 1,873E-08 2,253E-05 ! establishment of organelle localization GO:0051656 109 59 5,000 2,55E-08 2,045E-05 ! organelle localization GO:0051640 136 74 5,000 1,011E-07 6,082E-05 ! regulation of survival gene product expression GO:0045884 33 17 3,000 1,801E-07 8,666E-05 ! nuclear migration GO:0007097 12 6 2,000 5,302E-07 2,126E-04 ! establishment of spindle localization GO:0051293 12 6 2,000 5,302E-07 1,822E-04 GO:0051653|spindle localization, ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 5,302E-07 1,595E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of DNA replication GO:0006275 101 56 4,000 7,622E-07 2,038E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 9,258E-07 2,228E-04 ! macrophage differentiation GO:0030225 11 7 2,000 9,258E-07 2,025E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,478E-06 2,964E-04 ! myeloid cell differentiation GO:0030099 111 65 4,000 1,613E-06 2,986E-04 ! positive regulation of survival gene product expression GO:0045885 23 10 2,000 3,154E-06 5,42E-04 ! nucleus localization GO:0051647 19 11 2,000 4,327E-06 6,94E-04 ! establishment or maintenance of cell polarity GO:0007163 83 37 3,000 4,772E-06 7,176E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 5,756E-06 8,147E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 1,054E-05 1,409E-03 ! leukocyte differentiation GO:0002521 202 96 4,000 1,109E-05 1,404E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 1,155E-05 1,389E-03 ! isoprenoid biosynthetic process GO:0008299 32 15 2,000 1,183E-05 1,355E-03 ! interphase GO:0051325 213 98 4,000 1,226E-05 1,341E-03 ! filopodium assembly GO:0046847 32 16 2,000 1,452E-05 1,519E-03 ! microspike assembly GO:0030035 36 17 2,000 1,76E-05 1,764E-03 ! cytokine-mediated signaling pathway GO:0019221 97 59 3,000 3,126E-05 3,008E-03 ! cholesterol biosynthetic process GO:0006695 37 21 2,000 3,412E-05 3,157E-03 ! positive regulation of B cell activation GO:0050871 38 22 2,000 3,942E-05 3,513E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 5,849E-05 5,026E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 7,406E-05 6,144E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 7,406E-05 5,939E-03 ! regulation of transcription factor activity GO:0051090 126 74 3,000 7,634E-05 5,925E-03 GO:0090046|regulation of transcription regulator activity, ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 8,976E-05 6,749E-03 ! lipoprotein particle clearance GO:0034381 10 5 1,000 8,976E-05 6,545E-03 ! response to protozoan GO:0001562 10 5 1,000 8,976E-05 6,352E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 8,976E-05 6,171E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 8,976E-05 5,999E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 8,976E-05 5,837E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 8,976E-05 5,684E-03 ! lipoprotein catabolic process GO:0042159 11 5 1,000 8,976E-05 5,538E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 8,976E-05 5,399E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 8,976E-05 5,268E-03 ! metaphase GO:0051323 8 5 1,000 8,976E-05 5,142E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 9,211E-05 5,154E-03 ! sterol biosynthetic process GO:0016126 52 29 2,000 9,211E-05 5,037E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 1,021E-04 5,46E-03 ! cholesterol metabolic process GO:0008203 136 82 3,000 1,139E-04 5,959E-03 ! spindle organization GO:0007051 46 32 2,000 1,242E-04 6,359E-03 ! neuron remodeling GO:0016322 15 6 1,000 1,344E-04 6,736E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 1,000 1,344E-04 6,598E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 1,344E-04 6,466E-03 ! regulation of collagen metabolic process GO:0010712 9 6 1,000 1,344E-04 6,34E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 1,344E-04 6,218E-03 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 1,000 1,344E-04 6,1E-03 ! neutrophil homeostasis GO:0001780 10 6 1,000 1,344E-04 5,987E-03 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 1,344E-04 5,879E-03 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 1,000 1,344E-04 5,774E-03 ! organ or tissue specific immune response GO:0002251 7 6 1,000 1,344E-04 5,672E-03 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 2,000 1,492E-04 6,19E-03 ! regulation of DNA binding GO:0051101 155 88 3,000 1,498E-04 6,109E-03 ! sterol metabolic process GO:0016125 152 91 3,000 1,705E-04 6,838E-03 ! mitotic sister chromatid segregation GO:0000070 57 36 2,000 1,773E-04 6,991E-03 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 2,000 1,773E-04 6,879E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,878E-04 7,171E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,878E-04 7,059E-03 ! coenzyme A metabolic process GO:0015936 12 7 1,000 1,878E-04 6,95E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 1,878E-04 6,845E-03 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 1,878E-04 6,743E-03 ! defense response to Gram-negative bacterium GO:0050829 9 7 1,000 1,878E-04 6,644E-03 ! meiosis I GO:0007127 65 37 2,000 1,925E-04 6,711E-03 ! sister chromatid segregation GO:0000819 58 37 2,000 1,925E-04 6,616E-03 ! isoprenoid metabolic process GO:0006720 66 38 2,000 2,085E-04 7,066E-03 ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 2,085E-04 6,968E-03 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 2,000 2,431E-04 8,014E-03 ! cytokinesis GO:0000910 72 40 2,000 2,431E-04 7,905E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 2,499E-04 8,016E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 2,499E-04 7,91E-03 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 1,000 2,499E-04 7,807E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 2,499E-04 7,707E-03 ! myeloid cell homeostasis GO:0002262 13 8 1,000 2,499E-04 7,61E-03 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 2,499E-04 7,515E-03 GO:0000076|DNA replication checkpoint, ! positive regulation of transcription factor activity GO:0051091 62 42 2,000 2,813E-04 8,355E-03 GO:0090047|positive regulation of transcription regulator activity, ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 3,206E-04 9,407E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 3,206E-04 9,294E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,206E-04 9,183E-03 ! intestinal cholesterol absorption GO:0030299 16 9 1,000 3,206E-04 9,075E-03 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 3,206E-04 8,97E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 3,206E-04 8,867E-03 ! regulation of JAK-STAT cascade GO:0046425 70 45 2,000 3,454E-04 9,444E-03 ! leukocyte migration GO:0050900 68 45 2,000 3,454E-04 9,338E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 3,454E-04 9,234E-03 ! pigmentation GO:0043473 100 46 2,000 3,687E-04 9,749E-03 ! positive regulation of DNA binding GO:0043388 73 47 2,000 3,93E-04 0,01027755 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4E-04 0,01034793 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4E-04 0,01023784 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 1,000 4E-04 0,01013008 GO:0007520|myoblast fusion, ! COPI coating of Golgi vesicle GO:0048205 19 10 1,000 4E-04 0,01002456 GO:0048200|Golgi transport vesicle coating, ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 4E-04 9,921E-03 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 4E-04 9,82E-03 ! polyamine biosynthetic process GO:0006596 12 10 1,000 4E-04 9,721E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 4E-04 9,624E-03 GO:0045685|regulation of glial cell differentiation, ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 4E-04 9,528E-03 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 4E-04 9,435E-03 ! salivary gland development GO:0007431 27 10 1,000 4E-04 9,343E-03 ! positive regulation of acute inflammatory response GO:0002675 16 10 1,000 4E-04 9,253E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 4E-04 9,165E-03 ! establishment of cell polarity GO:0030010 16 10 1,000 4E-04 9,079E-03 ! cellular component disassembly GO:0022411 86 48 2,000 4,183E-04 9,405E-03 ! regulation of inflammatory response GO:0050727 75 48 2,000 4,183E-04 9,318E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 4,183E-04 9,233E-03 ! regulation of cell projection organization GO:0031344 121 50 2,000 4,719E-04 0,01032241 ! regulation of gene expression, epigenetic GO:0040029 105 50 2,000 4,719E-04 0,01022941 ! Golgi vesicle budding GO:0048194 22 11 1,000 4,879E-04 0,01048126 ! detection of mechanical stimulus GO:0050982 22 11 1,000 4,879E-04 0,01038851 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 4,879E-04 0,01029738 ! syncytium formation GO:0006949 18 11 1,000 4,879E-04 0,01020784 ! lipid digestion GO:0044241 18 11 1,000 4,879E-04 0,01011984 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 4,879E-04 0,01003334 ! DNA methylation GO:0006306 19 11 1,000 4,879E-04 9,948E-03 GO:0006305|DNA alkylation, ! neuroblast proliferation GO:0007405 24 11 1,000 4,879E-04 9,865E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 4,879E-04 9,783E-03 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 4,879E-04 9,702E-03 ! germ cell migration GO:0008354 25 11 1,000 4,879E-04 9,622E-03 ! defense response to Gram-positive bacterium GO:0050830 13 11 1,000 4,879E-04 9,544E-03 ! positive regulation of binding GO:0051099 78 51 2,000 5,003E-04 9,708E-03 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 5,003E-04 9,63E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 5,003E-04 9,554E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! covalent chromatin modification GO:0016569 101 52 2,000 5,298E-04 0,01003717 ! regulation of B cell proliferation GO:0030888 20 12 1,000 5,843E-04 0,01098368 ! hippocampus development GO:0021766 26 12 1,000 5,843E-04 0,01089854 ! polyamine metabolic process GO:0006595 17 12 1,000 5,843E-04 0,0108147 ! membrane protein proteolysis GO:0033619 25 12 1,000 5,843E-04 0,01073215 GO:0006509|membrane protein ectodomain proteolysis, ! entry into host cell GO:0030260 32 12 1,000 5,843E-04 0,01065085 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 5,843E-04 0,01057076 ! gland morphogenesis GO:0022612 29 12 1,000 5,843E-04 0,01049188 ! peptidyl-lysine modification GO:0018205 21 12 1,000 5,843E-04 0,01041416 ! regulation of chemokine production GO:0032642 18 13 1,000 6,892E-04 0,01219313 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 6,892E-04 0,01210413 ! endocrine pancreas development GO:0031018 22 13 1,000 6,892E-04 0,01201642 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 6,892E-04 0,01192997 ! exocrine system development GO:0035272 32 13 1,000 6,892E-04 0,01184475 ! chromatin silencing GO:0006342 26 13 1,000 6,892E-04 0,01176075 ! regulation of acute inflammatory response GO:0002673 21 13 1,000 6,892E-04 0,01167793 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 6,892E-04 0,01159626 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 6,892E-04 0,01151573 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 8,025E-04 0,01331614 ! myotube differentiation GO:0014902 25 14 1,000 8,025E-04 0,01322494 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 1,000 8,025E-04 0,01313497 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 8,025E-04 0,01304622 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 8,025E-04 0,01295866 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 8,025E-04 0,01287227 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 8,025E-04 0,01278703 ! intestinal absorption GO:0050892 25 14 1,000 8,025E-04 0,0127029 ! regulation of RNA stability GO:0043487 32 14 1,000 8,025E-04 0,01261987 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 8,025E-04 0,01253793 ! regulation of protein complex assembly GO:0043254 117 61 2,000 8,46E-04 0,01313266 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 8,46E-04 0,01304848 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 9,242E-04 0,01416252 ! vesicle coating GO:0006901 33 15 1,000 9,242E-04 0,01407288 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 9,242E-04 0,01398437 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 9,294E-04 0,01397659 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,054E-03 0,0157526 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 1,054E-03 0,01565536 ! DNA replication initiation GO:0006270 27 16 1,000 1,054E-03 0,01555932 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 1,054E-03 0,01546444 ! negative regulation of inflammatory response GO:0050728 22 16 1,000 1,054E-03 0,01537072 ! defense response to virus GO:0051607 37 16 1,000 1,054E-03 0,01527812 ! cell projection assembly GO:0030031 120 66 2,000 1,064E-03 0,01533002 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 1,112E-03 0,0159184 ! chromosome segregation GO:0007059 113 67 2,000 1,112E-03 0,0158242 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 1,112E-03 0,01573112 ! negative regulation of kinase activity GO:0033673 131 68 2,000 1,16E-03 0,01632536 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 1,192E-03 0,01667837 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 1,192E-03 0,01658196 ! endothelial cell migration GO:0043542 28 17 1,000 1,192E-03 0,01648666 ! limbic system development GO:0021761 36 17 1,000 1,192E-03 0,01639245 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 1,192E-03 0,01629931 ! membrane budding GO:0006900 37 17 1,000 1,192E-03 0,01620723 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 1,192E-03 0,01611617 ! neuron maturation GO:0042551 42 18 1,000 1,339E-03 0,017994 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 1,339E-03 0,01789404 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,339E-03 0,01779517 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 1,000 1,339E-03 0,0176974 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 1,339E-03 0,01760069 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 1,339E-03 0,01750504 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 1,369E-03 0,01780196 ! negative regulation of transferase activity GO:0051348 140 72 2,000 1,369E-03 0,01770626 ! meiosis GO:0007126 121 74 2,000 1,481E-03 0,01905929 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of translation GO:0045727 30 19 1,000 1,493E-03 0,01911059 ! negative regulation of defense response GO:0031348 25 19 1,000 1,493E-03 0,01900948 ! lipid phosphorylation GO:0046834 35 19 1,000 1,493E-03 0,01890943 ! mitotic chromosome condensation GO:0007076 34 19 1,000 1,493E-03 0,01881043 ! pigmentation during development GO:0048066 41 19 1,000 1,493E-03 0,01871246 ! plasma membrane fusion GO:0045026 28 19 1,000 1,493E-03 0,0186155 ! peptide cross-linking GO:0018149 37 19 1,000 1,493E-03 0,01851955 ! visual learning GO:0008542 36 19 1,000 1,493E-03 0,01842457 ! G1 phase GO:0051318 40 19 1,000 1,493E-03 0,01833057 ! peptide hormone secretion GO:0030072 31 19 1,000 1,493E-03 0,01823752 ! meiotic cell cycle GO:0051321 122 75 2,000 1,54E-03 0,01870973 ! steroid biosynthetic process GO:0006694 131 76 2,000 1,599E-03 0,01933864 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,656E-03 0,01992078 ! response to alkaloid GO:0043279 38 20 1,000 1,656E-03 0,01982167 ! pancreas development GO:0031016 35 20 1,000 1,656E-03 0,01972354 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,656E-03 0,01962638 ! peptide secretion GO:0002790 35 20 1,000 1,656E-03 0,01953017 ! actin filament-based movement GO:0030048 43 20 1,000 1,656E-03 0,01943491 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 1,661E-03 0,01939664 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 1,788E-03 0,02077696 ! hormone secretion GO:0046879 38 21 1,000 1,827E-03 0,02112932 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 1,827E-03 0,02102823 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 1,827E-03 0,02092809 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 1,827E-03 0,02082891 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 1,827E-03 0,02073066 ! DNA modification GO:0006304 34 21 1,000 1,827E-03 0,02063333 ! positive regulation of locomotion GO:0040017 39 21 1,000 1,827E-03 0,02053691 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 41 21 1,000 1,827E-03 0,02044139 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 1,827E-03 0,02034676 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 1,827E-03 0,02025299 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 1,92E-03 0,02119326 GO:0045937|positive regulation of phosphate metabolic process, ! response to drug GO:0042493 143 82 2,000 1,989E-03 0,02185008 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 2,005E-03 0,02193138 ! regulation of chemotaxis GO:0050920 40 22 1,000 2,005E-03 0,02183215 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 2,005E-03 0,0217338 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 2,005E-03 0,02163634 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 2,005E-03 0,02153975 ! apoptotic nuclear changes GO:0030262 32 22 1,000 2,005E-03 0,02144402 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 2,005E-03 0,02134914 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 2,005E-03 0,02125509 ! negative regulation of transport GO:0051051 153 84 2,000 2,131E-03 0,02248318 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,192E-03 0,0230308 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 2,192E-03 0,02293067 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 2,192E-03 0,0228314 ! protein amino acid O-linked glycosylation GO:0006493 42 23 1,000 2,192E-03 0,02273299 ! visual behavior GO:0007632 42 23 1,000 2,192E-03 0,02263543 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 2,192E-03 0,02253869 ! purine ribonucleoside metabolic process GO:0046128 34 23 1,000 2,192E-03 0,02244278 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 1,000 2,192E-03 0,02234769 ! regulation of interleukin-6 production GO:0032675 29 23 1,000 2,192E-03 0,02225339 ! platelet activation GO:0030168 37 23 1,000 2,192E-03 0,02215989 ! hormone transport GO:0009914 40 23 1,000 2,192E-03 0,02206717 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 2,192E-03 0,02197523 ! positive regulation of cell activation GO:0050867 145 85 2,000 2,204E-03 0,02200074 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 154 87 2,000 2,355E-03 0,02341062 GO:0070201|regulation of establishment of protein localization, ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,387E-03 0,02363058 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 2,387E-03 0,02353373 ! digestive system process GO:0022600 39 24 1,000 2,387E-03 0,02343768 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 2,387E-03 0,0233424 ! regulation of behavior GO:0050795 43 24 1,000 2,387E-03 0,0232479 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 2,387E-03 0,02315416 ! lymphocyte proliferation GO:0046651 48 24 1,000 2,387E-03 0,02306117 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,387E-03 0,02296892 ! pallium development GO:0021543 49 24 1,000 2,387E-03 0,02287742 ! leukocyte homeostasis GO:0001776 44 24 1,000 2,387E-03 0,02278663 ! positive regulation of protein modification process GO:0031401 136 88 2,000 2,433E-03 0,02313282 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 2,589E-03 0,02452488 ! negative regulation of DNA replication GO:0008156 42 25 1,000 2,589E-03 0,0244287 ! chromosome condensation GO:0030261 45 25 1,000 2,589E-03 0,02433328 ! negative regulation of cell development GO:0010721 73 25 1,000 2,589E-03 0,02423859 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 2,589E-03 0,02414465 ! somitogenesis GO:0001756 43 25 1,000 2,589E-03 0,02405142 ! positive regulation of protein secretion GO:0050714 36 25 1,000 2,589E-03 0,02395892 ! regulation of defense response GO:0031347 149 92 2,000 2,76E-03 0,02543954 ! initiation of viral infection GO:0019059 57 26 1,000 2,799E-03 0,02570687 ! macromolecular complex disassembly GO:0032984 53 26 1,000 2,799E-03 0,02560913 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 2,799E-03 0,02551213 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 2,799E-03 0,02541585 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,799E-03 0,0253203 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,799E-03 0,02522547 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 2,799E-03 0,02513135 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 2,799E-03 0,02503792 ! positive regulation of nuclear division GO:0051785 40 26 1,000 2,799E-03 0,02494519 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 1,000 2,799E-03 0,02485314 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 2,799E-03 0,02476177 ! leukocyte proliferation GO:0070661 52 26 1,000 2,799E-03 0,02467107 GO:0032943|mononuclear cell proliferation, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 3,017E-03 0,02649548 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 3,017E-03 0,02639914 ! protein amino acid acylation GO:0043543 55 27 1,000 3,017E-03 0,02630349 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 3,017E-03 0,02620853 ! regulation of protein localization GO:0032880 176 97 2,000 3,205E-03 0,0277389 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 3,243E-03 0,02796734 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 3,243E-03 0,02786746 ! skeletal muscle tissue development GO:0007519 186 99 2,000 3,395E-03 0,02906771 GO:0060538|skeletal muscle organ development, ! cellular iron ion homeostasis GO:0006879 51 29 1,000 3,477E-03 0,02966122 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 3,477E-03 0,02955641 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 3,477E-03 0,02945234 ! cell cycle arrest GO:0007050 213 100 2,000 3,492E-03 0,02948214 ! acute-phase response GO:0006953 49 30 1,000 3,718E-03 0,03127404 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 3,966E-03 0,03324916 ! cholesterol homeostasis GO:0042632 53 31 1,000 3,966E-03 0,03313371 GO:0055092|sterol homeostasis, ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 3,966E-03 0,03301906 ! peptide transport GO:0015833 55 31 1,000 3,966E-03 0,0329052 ! iron ion homeostasis GO:0055072 54 31 1,000 3,966E-03 0,03279212 ! myeloid leukocyte activation GO:0002274 49 31 1,000 3,966E-03 0,03267982 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 3,966E-03 0,03256829 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 4,222E-03 0,03455358 ! response to mechanical stimulus GO:0009612 57 32 1,000 4,222E-03 0,03443645 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 4,222E-03 0,03432011 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 4,222E-03 0,03420455 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 4,222E-03 0,03408977 ! gene silencing GO:0016458 65 32 1,000 4,222E-03 0,03397576 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 4,222E-03 0,0338625 ! cholesterol transport GO:0030301 56 32 1,000 4,222E-03 0,03375 ! sterol transport GO:0015918 57 33 1,000 4,486E-03 0,03573838 ! leukocyte chemotaxis GO:0030595 50 33 1,000 4,486E-03 0,03562043 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 69 33 1,000 4,486E-03 0,03550326 ! establishment of vesicle localization GO:0051650 61 33 1,000 4,486E-03 0,03538686 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 4,757E-03 0,03740234 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 4,757E-03 0,03728051 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 5,035E-03 0,03933446 ! negative regulation of secretion GO:0051048 63 35 1,000 5,035E-03 0,03920717 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 5,035E-03 0,03908069 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 5,035E-03 0,03895503 ! telencephalon development GO:0021537 68 35 1,000 5,035E-03 0,03883018 ! vesicle localization GO:0051648 64 35 1,000 5,035E-03 0,03870612 ! maintenance of protein location in cell GO:0032507 86 36 1,000 5,321E-03 0,04077254 ! DNA integrity checkpoint GO:0031570 75 36 1,000 5,321E-03 0,0406431 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 5,321E-03 0,04051448 ! negative regulation of DNA binding GO:0043392 68 37 1,000 5,614E-03 0,04261101 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 5,614E-03 0,04247701 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 5,914E-03 0,04460892 ! nucleus organization GO:0006997 67 38 1,000 5,914E-03 0,04446952 ! lipid homeostasis GO:0055088 67 38 1,000 5,914E-03 0,04433098 ! learning GO:0007612 77 39 1,000 6,222E-03 0,0464911 ! ear morphogenesis GO:0042471 60 39 1,000 6,222E-03 0,04634716 ! segmentation GO:0035282 67 39 1,000 6,222E-03 0,04620412 ! Rho protein signal transduction GO:0007266 74 39 1,000 6,222E-03 0,04606195 ! regulation of hormone secretion GO:0046883 62 40 1,000 6,537E-03 0,04824309 ! negative regulation of binding GO:0051100 72 40 1,000 6,537E-03 0,04809555 ! ribonucleoside metabolic process GO:0009119 55 40 1,000 6,537E-03 0,04794892 ! maintenance of protein location GO:0045185 91 40 1,000 6,537E-03 0,04780318 ! regulation of T cell proliferation GO:0042129 71 41 1,000 6,858E-03 0,05000447 ! keratinocyte differentiation GO:0030216 62 41 1,000 6,858E-03 0,0498534 ! regulation of T cell differentiation GO:0045580 70 41 1,000 6,858E-03 0,04970324 ! response to reactive oxygen species GO:0000302 67 42 1,000 7,187E-03 0,05193006 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 7,187E-03 0,05177458 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 7,187E-03 0,05162003 ! regulation of protein secretion GO:0050708 71 42 1,000 7,187E-03 0,0514664 ! epithelial cell differentiation GO:0030855 79 43 1,000 7,523E-03 0,0537117 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 7,523E-03 0,05355279 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 7,523E-03 0,05339482 ! biopolymer methylation GO:0043414 84 44 1,000 7,866E-03 0,05566403 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 7,866E-03 0,0555008 ! maintenance of location in cell GO:0051651 97 44 1,000 7,866E-03 0,05533851 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 8,216E-03 0,05763086 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 8,573E-03 0,05995808 ! epidermal cell differentiation GO:0009913 68 46 1,000 8,573E-03 0,05978429 ! response to insulin stimulus GO:0032868 95 46 1,000 8,573E-03 0,0596115 ! positive regulation of protein transport GO:0051222 72 46 1,000 8,573E-03 0,05943971 ! positive regulation of defense response GO:0031349 76 47 1,000 8,936E-03 0,06178232 ! regulation of adaptive immune response GO:0002819 84 47 1,000 8,936E-03 0,0616053 ! methylation GO:0032259 90 47 1,000 8,936E-03 0,06142928 ! positive regulation of cell cycle GO:0045787 89 48 1,000 9,306E-03 0,06379284 ! activation of caspase activity GO:0006919 84 48 1,000 9,306E-03 0,06361161 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 9,306E-03 0,06343141 ! endocrine system development GO:0035270 104 49 1,000 9,684E-03 0,06581522 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 9,684E-03 0,06562983 ! detection of abiotic stimulus GO:0009582 74 49 1,000 9,684E-03 0,06544548 ! regulation of ossification GO:0030278 117 50 1,000 0,01006735 0,06784889 ! histone modification GO:0016570 91 50 1,000 0,01006735 0,06765937 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,01006735 0,0674709 ! viral infectious cycle GO:0019058 99 51 1,000 0,01045784 0,06989326 ! chromatin remodeling GO:0006338 109 51 1,000 0,01045784 0,06969965 ! vesicle organization GO:0016050 107 51 1,000 0,01045784 0,06950711 ! regulation of cell shape GO:0008360 125 51 1,000 0,01045784 0,06931563 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01085497 0,07175013 ! membrane fusion GO:0006944 110 52 1,000 0,01085497 0,07155355 ! cell maturation GO:0048469 100 53 1,000 0,01125868 0,07401195 ! response to UV GO:0009411 104 53 1,000 0,01125868 0,07381028 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,01166893 0,07629197 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,01166893 0,07608522 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01208569 0,07858964 GO:0010952|positive regulation of peptidase activity, ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01250891 0,08112246 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,01250891 0,08090439 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,01293855 0,08345883 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01293855 0,08323567 ! muscle fiber development GO:0048747 112 57 1,000 0,01293855 0,08301371 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,01293855 0,08279293 ! lipid modification GO:0030258 97 57 1,000 0,01293855 0,08257332 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,01293855 0,08235487 ! maintenance of location GO:0051235 118 57 1,000 0,01293855 0,08213758 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01337456 0,08468209 ! positive regulation of secretion GO:0051047 95 59 1,000 0,01381691 0,08725326 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,01381691 0,08702485 ! DNA catabolic process GO:0006308 86 59 1,000 0,01381691 0,08679763 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,01381691 0,0865716 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,01426556 0,08915048 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,01426556 0,08891952 ! kidney development GO:0001822 122 60 1,000 0,01426556 0,08868976 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01501772 0,09312532 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01501772 0,09288592 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01501772 0,09264775 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01501772 0,0924108 ! neuron fate determination GO:0048664 7 5 0,000 0,01501772 0,09217506 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01501772 0,09194052 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01501772 0,09170717 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01501772 0,091475 ! polyol transport GO:0015791 12 5 0,000 0,01501772 0,091244 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01501772 0,09101417 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01501772 0,09078549 ! response to superoxide GO:0000303 10 5 0,000 0,01501772 0,09055795 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01501772 0,09033156 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01501772 0,09010629 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01501772 0,08988215 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01501772 0,08965912 ! female meiosis GO:0007143 7 5 0,000 0,01501772 0,08943719 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01501772 0,08921635 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01501772 0,08899661 ! cobalt ion transport GO:0006824 11 5 0,000 0,01501772 0,08877795 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01501772 0,08856035 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01501772 0,08834382 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01501772 0,08812835 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01501772 0,08791393 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01501772 0,08770054 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01501772 0,08748819 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01501772 0,08727687 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01501772 0,08706656 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01501772 0,08685727 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01501772 0,08664898 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01501772 0,08644168 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01501772 0,08623538 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01501772 0,08603006 ! negative chemotaxis GO:0050919 14 5 0,000 0,01501772 0,08582571 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01501772 0,08562233 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01501772 0,08541991 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01501772 0,08521845 ! behavioral response to pain GO:0048266 9 5 0,000 0,01501772 0,08501794 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01501772 0,08481837 ! Notch receptor processing GO:0007220 8 5 0,000 0,01501772 0,08461973 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01501772 0,08442202 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01501772 0,08422523 ! micturition GO:0060073 9 5 0,000 0,01501772 0,08402936 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01501772 0,08383439 ! copulation GO:0007620 9 5 0,000 0,01501772 0,08364033 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01501772 0,08344717 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01501772 0,08325489 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01501772 0,0830635 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01501772 0,08287299 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01501772 0,08268335 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01501772 0,08249457 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01501772 0,08230666 ! grooming behavior GO:0007625 6 5 0,000 0,01501772 0,0821196 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01501772 0,08193339 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01501772 0,08174802 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01501772 0,08156348 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01501772 0,08137978 ! lymph vessel development GO:0001945 10 5 0,000 0,01501772 0,08119691 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01501772 0,08101485 ! endochondral ossification GO:0001958 16 5 0,000 0,01501772 0,08083361 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01501772 0,08065318 ! parathyroid gland development GO:0060017 13 5 0,000 0,01501772 0,08047355 ! anagen GO:0042640 6 5 0,000 0,01501772 0,08029472 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01501772 0,08011668 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01501772 0,07993943 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01501772 0,07976297 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01501772 0,07958728 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01501772 0,07941236 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01501772 0,07923821 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01501772 0,07906482 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01501772 0,07889219 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01501772 0,07872031 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01501772 0,07854918 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01501772 0,07837879 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01501772 0,07820914 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01501772 0,07804022 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01501772 0,07787203 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01501772 0,07770457 ! histidine catabolic process GO:0006548 6 5 0,000 0,01501772 0,07753782 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01501772 0,07737179 ! microvillus organization GO:0032528 7 5 0,000 0,01501772 0,07720646 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01501772 0,07704184 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01501772 0,07687792 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01501772 0,0767147 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01501772 0,07655217 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01501772 0,07639032 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01501772 0,07622916 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01501772 0,07606868 ! polyol catabolic process GO:0046174 7 5 0,000 0,01501772 0,07590887 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01501772 0,07574974 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01501772 0,07559126 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01501772 0,07543345 ! muscle cell migration GO:0014812 8 5 0,000 0,01501772 0,0752763 ! mitochondrial fission GO:0000266 8 5 0,000 0,01501772 0,0751198 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01501772 0,07496395 ! mRNA transcription GO:0009299 9 5 0,000 0,01501772 0,07480874 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01501772 0,07465418 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01501772 0,07450026 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01501772 0,07434696 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01501772 0,0741943 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01501772 0,07404226 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01501772 0,07389085 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01501772 0,07374005 ! response to food GO:0032094 6 5 0,000 0,01501772 0,07358987 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01501772 0,07344029 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01501772 0,07329133 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01501772 0,07314296 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01501772 0,0729952 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01501772 0,07284803 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01501772 0,07270146 ! forebrain neuron development GO:0021884 13 5 0,000 0,01501772 0,07255547 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01501772 0,07241007 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01501772 0,07226525 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01501772 0,07212101 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01501772 0,07197734 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01501772 0,07183424 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01501772 0,07169171 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01501772 0,07154975 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01501772 0,07140835 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01501772 0,0712675 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01501772 0,07112721 ! basic amino acid transport GO:0015802 11 5 0,000 0,01501772 0,07098747 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01501772 0,07084828 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01501772 0,07070964 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01501772 0,07057153 ! depyrimidination GO:0045008 10 5 0,000 0,01501772 0,07043396 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01501772 0,07029693 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01501772 0,07016043 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01501772 0,07002446 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01501772 0,06988902 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01501772 0,0697541 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01501772 0,0696197 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01501772 0,06948581 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01501772 0,06935244 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01501772 0,06921959 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01501772 0,06908723 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01501772 0,06895539 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01501772 0,06882405 ! response to arsenic GO:0046685 10 5 0,000 0,01501772 0,0686932 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01501772 0,06856285 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01501772 0,068433 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01501772 0,06830364 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01501772 0,06817476 ! response to cadmium ion GO:0046686 7 5 0,000 0,01501772 0,06804637 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01501772 0,06791847 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01501772 0,06779104 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01501772 0,06766409 ! decidualization GO:0046697 11 5 0,000 0,01501772 0,06753761 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01501772 0,06741161 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01501772 0,06728608 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01501772 0,06716101 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01501772 0,06703641 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01501772 0,06691227 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01501772 0,06678858 ! neural tube patterning GO:0021532 7 5 0,000 0,01501772 0,06666536 ! embryonic cleavage GO:0040016 6 5 0,000 0,01501772 0,06654259 ! peroxisome fission GO:0016559 5 5 0,000 0,01501772 0,06642026 ! histone demethylation GO:0016577 10 5 0,000 0,01501772 0,06629839 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01501772 0,06617697 ! mitotic recombination GO:0006312 9 5 0,000 0,01501772 0,06605598 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01501772 0,06593544 ! metaphase plate congression GO:0051310 7 5 0,000 0,01501772 0,06581534 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01501772 0,06569568 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01501772 0,06557645 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01501772 0,06545765 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01501772 0,06533928 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01501772 0,06522134 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01501772 0,06510383 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01501772 0,06498673 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01501772 0,06487006 ! plasminogen activation GO:0031639 5 5 0,000 0,01501772 0,06475381 ! B cell homeostasis GO:0001782 13 5 0,000 0,01501772 0,06463797 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01501772 0,06452254 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01501772 0,06440753 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01501772 0,06429292 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01501772 0,06417873 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01501772 0,06406494 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01501772 0,06395155 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01501772 0,06383856 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01501772 0,06372597 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01501772 0,06361377 ! response to redox state GO:0051775 5 5 0,000 0,01501772 0,06350197 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01501772 0,06339057 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01501772 0,06327955 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01501772 0,06316892 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01501772 0,06305868 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01501772 0,06294882 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01501772 0,06283935 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01501772 0,06273025 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01501772 0,06262153 ! striatum development GO:0021756 9 5 0,000 0,01501772 0,06251319 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01501772 0,06240522 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01501772 0,06229763 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01501772 0,0621904 ! glial cell migration GO:0008347 11 5 0,000 0,01501772 0,06208355 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01501772 0,06197706 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01501772 0,06187093 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01501772 0,06176517 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01501772 0,06165977 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01501772 0,06155473 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01501772 0,06145004 ! neuroprotection GO:0043526 6 5 0,000 0,01501772 0,06134571 ! neural plate development GO:0001840 8 5 0,000 0,01501772 0,06124174 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01501772 0,06113811 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01501772 0,06103484 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01501772 0,06093191 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01501772 0,06082933 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01501772 0,0607271 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01501772 0,06062521 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01501772 0,06052366 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01501772 0,06042245 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01501772 0,06032158 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01501772 0,06022104 ! spindle assembly GO:0051225 6 5 0,000 0,01501772 0,06012084 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01501772 0,06002097 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01501772 0,05992143 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01501772 0,05982222 ! drug metabolic process GO:0017144 6 5 0,000 0,01501772 0,05972334 ! stem cell division GO:0017145 11 5 0,000 0,01501772 0,05962479 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01501772 0,05952656 ! organ regeneration GO:0031100 7 5 0,000 0,01501772 0,05942866 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01501772 0,05933107 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01501772 0,05923381 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01501772 0,05913686 ! ear development GO:0043583 103 62 1,000 0,01518157 0,05968441 ! viral reproductive process GO:0022415 126 62 1,000 0,01518157 0,05958704 ! gonad development GO:0008406 98 62 1,000 0,01518157 0,05948999 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,01518157 0,05939326 ! regulation of mitosis GO:0007088 105 63 1,000 0,01564885 0,06112198 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,01564885 0,06102291 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,01564885 0,06092417 ! positive regulation of cell motion GO:0051272 146 64 1,000 0,01612227 0,06266587 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,01660177 0,06442558 ! actin filament organization GO:0007015 148 66 1,000 0,01708732 0,06620306 ! developmental maturation GO:0021700 116 66 1,000 0,01708732 0,06609662 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,01757889 0,06788893 ! lung development GO:0030324 144 67 1,000 0,01757889 0,06778013 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,01757889 0,06767168 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,01757889 0,06756358 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01799438 0,06905021 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01799438 0,06894026 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01799438 0,06883066 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01799438 0,0687214 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01799438 0,06861249 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01799438 0,06850393 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01799438 0,06839571 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01799438 0,06828783 ! sleep GO:0030431 13 6 0,000 0,01799438 0,06818029 ! response to oxygen radical GO:0000305 11 6 0,000 0,01799438 0,06807309 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01799438 0,06796622 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01799438 0,06785969 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01799438 0,0677535 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01799438 0,06764763 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01799438 0,0675421 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01799438 0,06743689 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01799438 0,06733201 ! forebrain regionalization GO:0021871 8 6 0,000 0,01799438 0,06722746 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01799438 0,06712323 ! male meiosis GO:0007140 7 6 0,000 0,01799438 0,06701932 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01799438 0,06691574 ! response to zinc ion GO:0010043 9 6 0,000 0,01799438 0,06681248 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01799438 0,06670953 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01799438 0,0666069 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01799438 0,06650458 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01799438 0,06640258 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01799438 0,06630089 ! malate metabolic process GO:0006108 11 6 0,000 0,01799438 0,06619952 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01799438 0,06609845 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01799438 0,06599769 ! protein refolding GO:0042026 15 6 0,000 0,01799438 0,06589724 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01799438 0,06579709 ! opsonization GO:0008228 8 6 0,000 0,01799438 0,06569724 ! mating behavior GO:0007617 7 6 0,000 0,01799438 0,0655977 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01799438 0,06549846 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01799438 0,06539952 ! equilibrioception GO:0050957 14 6 0,000 0,01799438 0,06530088 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01799438 0,06520254 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01799438 0,06510449 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01799438 0,06500673 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01799438 0,06490927 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01799438 0,0648121 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01799438 0,06471522 ! toxin metabolic process GO:0009404 11 6 0,000 0,01799438 0,06461863 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01799438 0,06452233 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01799438 0,06442632 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01799438 0,06433059 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01799438 0,06423514 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01799438 0,06413998 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01799438 0,06404509 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01799438 0,06395049 ! thymic T cell selection GO:0045061 12 6 0,000 0,01799438 0,06385617 ! protein lipoylation GO:0009249 10 6 0,000 0,01799438 0,06376213 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01799438 0,06366836 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01799438 0,06357487 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01799438 0,06348165 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01799438 0,0633887 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01799438 0,06329603 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01799438 0,06320363 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01799438 0,06311149 ! response to pH GO:0009268 10 6 0,000 0,01799438 0,06301963 ! hyperosmotic response GO:0006972 9 6 0,000 0,01799438 0,06292803 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01799438 0,0628367 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01799438 0,06274563 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01799438 0,06265482 ! urea metabolic process GO:0019627 7 6 0,000 0,01799438 0,06256428 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01799438 0,062474 ! neutrophil activation GO:0042119 8 6 0,000 0,01799438 0,06238398 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01799438 0,06229422 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01799438 0,06220472 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01799438 0,06211547 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01799438 0,06202648 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01799438 0,06193775 ! neuron apoptosis GO:0051402 9 6 0,000 0,01799438 0,06184926 ! nucleoside salvage GO:0043174 9 6 0,000 0,01799438 0,06176103 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01799438 0,06167305 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01799438 0,06158533 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01799438 0,06149785 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01799438 0,06141062 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01799438 0,06132363 ! carnitine transport GO:0015879 10 6 0,000 0,01799438 0,06123689 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01799438 0,0611504 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01799438 0,06106415 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01799438 0,06097815 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01799438 0,06089238 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01799438 0,06080686 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01799438 0,06072158 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01799438 0,06063653 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01799438 0,06055173 ! neural nucleus development GO:0048857 14 6 0,000 0,01799438 0,06046716 ! response to UV-C GO:0010225 11 6 0,000 0,01799438 0,06038282 ! astrocyte development GO:0014002 15 6 0,000 0,01799438 0,06029872 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01799438 0,06021486 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01799438 0,06013123 ! interaction with symbiont GO:0051702 13 6 0,000 0,01799438 0,06004783 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01799438 0,05996466 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01799438 0,05988172 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01799438 0,05979901 ! response to copper ion GO:0046688 10 6 0,000 0,01799438 0,05971653 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01799438 0,05963428 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01799438 0,05955225 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01799438 0,05947044 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01799438 0,05938887 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01799438 0,05930751 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01799438 0,05922638 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01799438 0,05914547 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01799438 0,05906478 ! hair follicle maturation GO:0048820 7 6 0,000 0,01799438 0,05898431 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01799438 0,05890406 ! Schwann cell development GO:0014044 15 6 0,000 0,01799438 0,05882403 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01799438 0,05874421 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01799438 0,05866461 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01799438 0,05858523 ! subpallium development GO:0021544 10 6 0,000 0,01799438 0,05850606 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01799438 0,0584271 ! histone ubiquitination GO:0016574 8 6 0,000 0,01799438 0,05834836 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01799438 0,05826983 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01799438 0,05819151 ! G2 phase GO:0051319 16 6 0,000 0,01799438 0,0581134 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01799438 0,0580355 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01799438 0,05795781 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01799438 0,05788033 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01799438 0,05780305 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01799438 0,05772598 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01799438 0,05764911 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01799438 0,05757245 ! receptor internalization GO:0031623 10 6 0,000 0,01799438 0,05749599 ! protein deubiquitination GO:0016579 14 6 0,000 0,01799438 0,05741974 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01799438 0,05734369 ! protein destabilization GO:0031648 9 6 0,000 0,01799438 0,05726784 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01799438 0,05719218 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01799438 0,05711673 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01799438 0,05704148 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01799438 0,05696643 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01799438 0,05689157 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01799438 0,05681691 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01799438 0,05674244 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01799438 0,05666817 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01799438 0,0565941 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01799438 0,05652021 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01799438 0,05644652 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01799438 0,05637303 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01799438 0,05629972 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01799438 0,0562266 ! catecholamine transport GO:0051937 9 6 0,000 0,01799438 0,05615368 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01799438 0,05608094 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01799438 0,05600839 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01799438 0,05593603 ! maternal placenta development GO:0001893 12 6 0,000 0,01799438 0,05586385 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01799438 0,05579186 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01799438 0,05572006 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01799438 0,05564844 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01799438 0,055577 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01799438 0,05550575 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01799438 0,05543468 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01799438 0,05536379 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,01807642 0,05554517 ! viral reproduction GO:0016032 134 68 1,000 0,01807642 0,05547432 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,01857988 0,05694675 ! negative regulation of cell size GO:0045792 134 69 1,000 0,01857988 0,0568743 ! urogenital system development GO:0001655 137 69 1,000 0,01857988 0,05680203 ! respiratory tube development GO:0030323 150 70 1,000 0,01908924 0,05828516 ! reproductive structure development GO:0048608 113 71 1,000 0,01960444 0,05978237 ! humoral immune response GO:0006959 109 71 1,000 0,01960444 0,0597067 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,01960444 0,05963122 ! regulation of immune effector process GO:0002697 137 71 1,000 0,01960444 0,05955592 ! acute inflammatory response GO:0002526 113 72 1,000 0,02012546 0,06106162 ! regulation of caspase activity GO:0043281 122 72 1,000 0,02012546 0,06098471 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02012546 0,060908 ! respiratory system development GO:0060541 153 72 1,000 0,02012546 0,06083148 ! learning or memory GO:0007611 147 73 1,000 0,02065225 0,06234545 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,02065225 0,06226732 ! tRNA transcription GO:0009304 14 7 0,000 0,02096215 0,06312258 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02096215 0,06304367 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02096215 0,06296497 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02096215 0,06288646 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02096215 0,06280814 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02096215 0,06273002 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02096215 0,0626521 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02096215 0,06257436 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02096215 0,06249682 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02096215 0,06241948 ! prostate gland development GO:0030850 13 7 0,000 0,02096215 0,06234232 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02096215 0,06226535 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02096215 0,06218858 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02096215 0,06211199 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02096215 0,06203559 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02096215 0,06195938 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02096215 0,06188336 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02096215 0,06180752 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02096215 0,06173187 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02096215 0,0616564 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02096215 0,06158112 ! glycolipid transport GO:0046836 10 7 0,000 0,02096215 0,06150602 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02096215 0,06143111 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02096215 0,06135637 ! neuron adhesion GO:0007158 12 7 0,000 0,02096215 0,06128182 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02096215 0,06120745 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02096215 0,06113326 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02096215 0,06105925 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02096215 0,06098541 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02096215 0,06091176 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02096215 0,06083828 ! mRNA stabilization GO:0048255 18 7 0,000 0,02096215 0,06076498 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02096215 0,06069186 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02096215 0,06061892 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02096215 0,06054614 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02096215 0,06047355 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02096215 0,06040112 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02096215 0,06032887 ! lipoprotein transport GO:0042953 14 7 0,000 0,02096215 0,0602568 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02096215 0,06018489 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02096215 0,06011316 ! rhythmic behavior GO:0007622 15 7 0,000 0,02096215 0,06004159 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02096215 0,0599702 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02096215 0,05989898 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02096215 0,05982792 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02096215 0,05975704 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02096215 0,05968632 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02096215 0,05961577 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02096215 0,05954538 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02096215 0,05947516 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02096215 0,05940511 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02096215 0,05933522 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02096215 0,0592655 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02096215 0,05919594 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02096215 0,05912654 ! spinal cord patterning GO:0021511 13 7 0,000 0,02096215 0,0590573 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02096215 0,05898823 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02096215 0,05891932 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02096215 0,05885057 ! adrenal gland development GO:0030325 17 7 0,000 0,02096215 0,05878198 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02096215 0,05871355 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02096215 0,05864528 ! ovulation GO:0030728 9 7 0,000 0,02096215 0,05857716 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02096215 0,05850921 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02096215 0,05844141 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02096215 0,05837377 ! microtubule nucleation GO:0007020 20 7 0,000 0,02096215 0,05830629 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02096215 0,05823896 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02096215 0,05817178 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02096215 0,05810477 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02096215 0,0580379 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02096215 0,05797119 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02096215 0,05790464 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02096215 0,05783823 ! galactose metabolic process GO:0006012 13 7 0,000 0,02096215 0,05777198 ! vesicle fusion GO:0006906 17 7 0,000 0,02096215 0,05770588 ! response to dietary excess GO:0002021 8 7 0,000 0,02096215 0,05763993 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02096215 0,05757413 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02096215 0,05750848 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02096215 0,05744298 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02096215 0,05737763 ! organ growth GO:0035265 15 7 0,000 0,02096215 0,05731243 ! purine salvage GO:0043101 10 7 0,000 0,02096215 0,05724738 ! nucleoside transport GO:0015858 8 7 0,000 0,02096215 0,05718247 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02096215 0,05711771 ! parturition GO:0007567 14 7 0,000 0,02096215 0,0570531 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02096215 0,05698863 ! rRNA modification GO:0000154 14 7 0,000 0,02096215 0,05692431 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02096215 0,05686013 ! spindle checkpoint GO:0031577 15 7 0,000 0,02096215 0,0567961 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02096215 0,05673221 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02096215 0,05666847 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02096215 0,05660487 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02096215 0,05654141 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02096215 0,05647809 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02096215 0,05641492 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02096215 0,05635189 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02096215 0,05628899 ! fibrinolysis GO:0042730 10 7 0,000 0,02096215 0,05622624 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02096215 0,05616363 ! eating behavior GO:0042755 7 7 0,000 0,02096215 0,05610115 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02096215 0,05603882 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02096215 0,05597662 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02096215 0,05591456 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02096215 0,05585264 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02096215 0,05579086 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02096215 0,05572921 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02096215 0,0556677 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02096215 0,05560633 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02096215 0,05554509 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02096215 0,05548398 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02096215 0,05542301 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02096215 0,05536217 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02096215 0,05530147 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02096215 0,0552409 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02096215 0,05518046 ! regulation of meiosis GO:0040020 12 7 0,000 0,02096215 0,05512015 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02096215 0,05505998 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02096215 0,05499993 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02096215 0,05494002 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02096215 0,05488024 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02096215 0,05482058 ! transcription termination GO:0006353 13 7 0,000 0,02096215 0,05476106 ! response to tumor cell GO:0002347 13 7 0,000 0,02096215 0,05470167 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02096215 0,0546424 ! anaphase GO:0051322 17 7 0,000 0,02096215 0,05458327 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02096215 0,05452426 ! axonal fasciculation GO:0007413 18 7 0,000 0,02096215 0,05446538 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02096215 0,05440662 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02096215 0,05434799 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02096215 0,05428949 ! diuresis GO:0030146 12 7 0,000 0,02096215 0,05423112 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02096215 0,05417287 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02096215 0,05411474 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02096215 0,05405674 ! antibiotic transport GO:0042891 9 7 0,000 0,02096215 0,05399886 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02096215 0,05394111 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02096215 0,05388348 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02096215 0,05382597 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02096215 0,05376859 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02096215 0,05371133 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02096215 0,05365419 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02096215 0,05359717 ! lymph node development GO:0048535 10 7 0,000 0,02096215 0,05354027 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02096215 0,0534835 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02096215 0,05342684 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02096215 0,0533703 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02096215 0,05331389 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02096215 0,05325759 ! adult feeding behavior GO:0008343 9 7 0,000 0,02096215 0,05320141 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02096215 0,05314535 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02096215 0,05308941 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02096215 0,05303358 ! muscle adaptation GO:0043500 14 7 0,000 0,02096215 0,05297788 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02096215 0,05292228 ! retina homeostasis GO:0001895 12 7 0,000 0,02096215 0,05286681 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02096215 0,05281145 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02096215 0,05275621 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02096215 0,05270108 ! protein prenylation GO:0018342 18 7 0,000 0,02096215 0,05264607 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02096215 0,05259118 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02096215 0,05253639 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,02118478 0,0530391 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,02118478 0,05298397 ! eye development GO:0001654 143 74 1,000 0,02118478 0,05292895 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,02226688 0,0555748 ! defense response to bacterium GO:0042742 89 76 1,000 0,02226688 0,05551721 ! blood coagulation GO:0007596 146 78 1,000 0,02337145 0,05821089 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,02337145 0,05815069 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,02337145 0,05809062 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02392105 0,0593953 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02392105 0,05933407 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,02392105 0,05927296 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02392105 0,05921198 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02392105 0,05915113 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02392105 0,0590904 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02392105 0,05902979 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02392105 0,05896931 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02392105 0,05890895 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02392105 0,05884872 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02392105 0,05878861 ! meiotic prophase I GO:0007128 13 8 0,000 0,02392105 0,05872862 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02392105 0,05866875 ! oligopeptide transport GO:0006857 15 8 0,000 0,02392105 0,05860901 ! UTP metabolic process GO:0046051 8 8 0,000 0,02392105 0,05854939 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02392105 0,05848989 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02392105 0,05843051 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02392105 0,05837125 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02392105 0,05831211 ! succinate metabolic process GO:0006105 14 8 0,000 0,02392105 0,05825309 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02392105 0,05819418 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02392105 0,0581354 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02392105 0,05807674 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02392105 0,05801819 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02392105 0,05795977 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02392105 0,05790146 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02392105 0,05784326 ! reflex GO:0060004 16 8 0,000 0,02392105 0,05778519 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02392105 0,05772723 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02392105 0,05766939 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02392105 0,05761166 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02392105 0,05755405 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02392105 0,05749655 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02392105 0,05743917 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02392105 0,0573819 ! pigment granule organization GO:0048753 16 8 0,000 0,02392105 0,05732475 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02392105 0,05726771 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02392105 0,05721078 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02392105 0,05715397 ! histidine metabolic process GO:0006547 16 8 0,000 0,02392105 0,05709727 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02392105 0,05704068 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02392105 0,05698421 ! glycine catabolic process GO:0006546 13 8 0,000 0,02392105 0,05692784 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02392105 0,05687159 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02392105 0,05681545 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,02392105 0,05675942 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02392105 0,0567035 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02392105 0,05664769 ! melanin metabolic process GO:0006582 15 8 0,000 0,02392105 0,05659198 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02392105 0,05653639 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02392105 0,05648091 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02392105 0,05642554 ! macrophage activation GO:0042116 12 8 0,000 0,02392105 0,05637027 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02392105 0,05631512 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02392105 0,05626007 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02392105 0,05620513 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02392105 0,05615029 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02392105 0,05609556 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02392105 0,05604094 ! osteoblast development GO:0002076 16 8 0,000 0,02392105 0,05598643 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02392105 0,05593202 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02392105 0,05587772 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02392105 0,05582352 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02392105 0,05576943 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02392105 0,05571544 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02392105 0,05566156 ! response to UV-B GO:0010224 16 8 0,000 0,02392105 0,05560778 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02392105 0,0555541 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02392105 0,05550053 ! intermediate filament organization GO:0045109 12 8 0,000 0,02392105 0,05544706 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02392105 0,05539369 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02392105 0,05534043 ! cellular extravasation GO:0045123 12 8 0,000 0,02392105 0,05528727 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02392105 0,05523421 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02392105 0,05518125 ! response to antibiotic GO:0046677 11 8 0,000 0,02392105 0,0551284 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02392105 0,05507564 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02392105 0,05502299 ! DNA topological change GO:0006265 12 8 0,000 0,02392105 0,05497044 ! response to tropane GO:0014073 15 8 0,000 0,02392105 0,05491798 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02392105 0,05486563 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02392105 0,05481338 ! melanosome transport GO:0032402 13 8 0,000 0,02392105 0,05476123 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02392105 0,05470917 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02392105 0,05465722 ! mast cell activation GO:0045576 14 8 0,000 0,02392105 0,05460536 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02392105 0,0545536 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02392105 0,05450194 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02392105 0,05445038 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02392105 0,05439891 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02392105 0,05434754 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02392105 0,05429627 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02392105 0,0542451 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02392105 0,05419402 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02392105 0,05414304 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02392105 0,05409215 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02392105 0,05404136 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02392105 0,05399066 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02392105 0,05394006 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02392105 0,05388956 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02392105 0,05383915 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02392105 0,05378883 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02392105 0,05373861 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02392105 0,05368848 ! hormone catabolic process GO:0042447 17 8 0,000 0,02392105 0,05363844 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02392105 0,0535885 GO:0010828|positive regulation of glucose transport, ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02392105 0,05353865 ! ATP catabolic process GO:0006200 11 8 0,000 0,02392105 0,05348889 ! blastocyst growth GO:0001832 19 8 0,000 0,02392105 0,05343923 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02392105 0,05338966 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02392105 0,05334017 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02392105 0,05329079 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02392105 0,05324149 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02392105 0,05319228 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02392105 0,05314317 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02392105 0,05309414 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02392105 0,05304521 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02392105 0,05299636 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02392105 0,05294761 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02392105 0,05289894 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02392105 0,05285037 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02392105 0,05280188 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02392105 0,05275348 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02392105 0,05270517 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02392105 0,05265695 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02393208 0,05263306 ! muscle cell differentiation GO:0042692 159 80 1,000 0,0244982 0,05382892 ! T cell activation GO:0042110 168 81 1,000 0,02506979 0,0550346 ! response to hypoxia GO:0001666 171 81 1,000 0,02506979 0,05498444 ! digestion GO:0007586 112 81 1,000 0,02506979 0,05493436 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,02506979 0,05488437 ! response to nutrient GO:0007584 125 82 1,000 0,02564682 0,05609659 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,02564682 0,05604564 ! response to oxygen levels GO:0070482 176 83 1,000 0,02622923 0,05726637 ! hemostasis GO:0007599 158 84 1,000 0,02681701 0,05849657 ! negative regulation of growth GO:0045926 155 84 1,000 0,02681701 0,05844359 ! regulation of developmental growth GO:0048638 15 9 0,000 0,02687111 0,05850849 ! axon extension GO:0048675 15 9 0,000 0,02687111 0,05845559 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02687111 0,05840278 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02687111 0,05835007 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02687111 0,05829746 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02687111 0,05824494 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02687111 0,05819251 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02687111 0,05814018 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02687111 0,05808794 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02687111 0,0580358 ! phosphate transport GO:0006817 19 9 0,000 0,02687111 0,05798375 ! reproductive behavior GO:0019098 19 9 0,000 0,02687111 0,05793179 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02687111 0,05787993 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02687111 0,05782816 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02687111 0,05777648 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02687111 0,05772489 ! GTP metabolic process GO:0046039 9 9 0,000 0,02687111 0,0576734 ! RNA methylation GO:0001510 15 9 0,000 0,02687111 0,057622 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02687111 0,05757068 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02687111 0,05751947 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02687111 0,05746834 ! artery development GO:0060840 24 9 0,000 0,02687111 0,0574173 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02687111 0,05736635 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02687111 0,0573155 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02687111 0,05726473 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02687111 0,05721405 ! chemosensory behavior GO:0007635 20 9 0,000 0,02687111 0,05716346 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02687111 0,05711297 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02687111 0,05706256 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02687111 0,05701224 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02687111 0,05696201 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02687111 0,05691187 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02687111 0,05686181 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02687111 0,05681184 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02687111 0,05676197 ! protein targeting to ER GO:0045047 22 9 0,000 0,02687111 0,05671217 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02687111 0,05666247 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02687111 0,05661285 ! T cell selection GO:0045058 23 9 0,000 0,02687111 0,05656332 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02687111 0,05651388 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02687111 0,05646452 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02687111 0,05641525 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02687111 0,05636607 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02687111 0,05631697 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02687111 0,05626795 ! mannose metabolic process GO:0006013 13 9 0,000 0,02687111 0,05621903 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02687111 0,05617018 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02687111 0,05612142 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02687111 0,05607275 ! receptor clustering GO:0043113 18 9 0,000 0,02687111 0,05602416 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02687111 0,05597565 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02687111 0,05592723 ! ruffle organization GO:0031529 15 9 0,000 0,02687111 0,05587889 ! retinol metabolic process GO:0042572 18 9 0,000 0,02687111 0,05583064 ! behavioral fear response GO:0001662 22 9 0,000 0,02687111 0,05578247 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02687111 0,05573438 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02687111 0,05568637 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02687111 0,05563845 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02687111 0,05559061 ! protein heterooligomerization GO:0051291 16 9 0,000 0,02687111 0,05554285 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02687111 0,05549517 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02687111 0,05544758 ! segment specification GO:0007379 13 9 0,000 0,02687111 0,05540007 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02687111 0,05535264 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02687111 0,05530529 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02687111 0,05525802 ! response to amine stimulus GO:0014075 13 9 0,000 0,02687111 0,05521083 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02687111 0,05516372 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02687111 0,05511669 ! erythrocyte development GO:0048821 15 9 0,000 0,02687111 0,05506974 ! gas homeostasis GO:0033483 16 9 0,000 0,02687111 0,05502288 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02687111 0,05497609 ! renal water homeostasis GO:0003091 14 9 0,000 0,02687111 0,05492938 ! postreplication repair GO:0006301 22 9 0,000 0,02687111 0,05488275 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02687111 0,0548362 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02687111 0,05478973 ! icosanoid secretion GO:0032309 15 9 0,000 0,02687111 0,05474334 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02687111 0,05469702 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02687111 0,05465079 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02687111 0,05460463 ! regulation of cell division GO:0051302 15 9 0,000 0,02687111 0,05455855 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02687111 0,05451255 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02687111 0,05446662 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02687111 0,05442077 ! sterol catabolic process GO:0016127 11 9 0,000 0,02687111 0,054375 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02687111 0,05432931 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02687111 0,05428369 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02687111 0,05423815 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02687111 0,05419269 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02687111 0,0541473 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02687111 0,05410199 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02687111 0,05405675 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02687111 0,05401159 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02687111 0,05396651 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02687111 0,0539215 ! purine base metabolic process GO:0006144 21 9 0,000 0,02687111 0,05387657 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02687111 0,05383171 ! pigment granule transport GO:0051904 17 9 0,000 0,02687111 0,05378692 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02687111 0,05374221 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02687111 0,05369757 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02687111 0,05365301 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02687111 0,05360852 ! mitochondrion localization GO:0051646 15 9 0,000 0,02687111 0,05356411 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,0274101 0,05459329 ! amine biosynthetic process GO:0009309 138 86 1,000 0,02800847 0,05573894 ! chromatin assembly GO:0031497 124 86 1,000 0,02800847 0,05569288 ! mitochondrion organization GO:0007005 148 86 1,000 0,02800847 0,05564689 ! gland development GO:0048732 206 88 1,000 0,02922092 0,05800786 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02981234 0,05913313 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02981234 0,05908443 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02981234 0,0590358 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02981234 0,05898725 ! synapsis GO:0007129 13 10 0,000 0,02981234 0,05893878 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02981234 0,05889039 ! N-glycan processing GO:0006491 20 10 0,000 0,02981234 0,05884208 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02981234 0,05879385 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02981234 0,05874569 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02981234 0,05869762 ! social behavior GO:0035176 24 10 0,000 0,02981234 0,05864963 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02981234 0,05860171 ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02981234 0,05855387 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02981234 0,05850611 ! androgen metabolic process GO:0008209 17 10 0,000 0,02981234 0,05845843 ! phospholipid efflux GO:0033700 16 10 0,000 0,02981234 0,05841082 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02981234 0,0583633 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02981234 0,05831585 ! lung alveolus development GO:0048286 26 10 0,000 0,02981234 0,05826847 ! pathogenesis GO:0009405 13 10 0,000 0,02981234 0,05822118 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02981234 0,05817396 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02981234 0,05812682 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02981234 0,05807975 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02981234 0,05803276 ! endoderm development GO:0007492 16 10 0,000 0,02981234 0,05798585 ! arginine catabolic process GO:0006527 13 10 0,000 0,02981234 0,05793901 ! proline metabolic process GO:0006560 13 10 0,000 0,02981234 0,05789225 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02981234 0,05784556 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02981234 0,05779895 ! V(D)J recombination GO:0033151 28 10 0,000 0,02981234 0,05775241 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02981234 0,05770595 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02981234 0,05765956 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02981234 0,05761325 ! B cell proliferation GO:0042100 18 10 0,000 0,02981234 0,05756701 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02981234 0,05752084 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02981234 0,05747475 ! multicellular organism growth GO:0035264 18 10 0,000 0,02981234 0,05742874 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02981234 0,05738279 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02981234 0,05733692 ! epithelial cell development GO:0002064 20 10 0,000 0,02981234 0,05729113 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02981234 0,0572454 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02981234 0,05719975 ! macroautophagy GO:0016236 17 10 0,000 0,02981234 0,05715418 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02981234 0,05710867 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02981234 0,05706324 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02981234 0,05701788 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02981234 0,05697259 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02981234 0,05692737 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02981234 0,05688223 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02981234 0,05683716 ! brain morphogenesis GO:0048854 23 10 0,000 0,02981234 0,05679216 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02981234 0,05674722 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02981234 0,05670237 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02981234 0,05665758 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02981234 0,05661286 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02981234 0,05656821 ! response to dsRNA GO:0043331 20 10 0,000 0,02981234 0,05652363 ! DNA ligation GO:0006266 19 10 0,000 0,02981234 0,05647913 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02981234 0,05643469 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02981234 0,05639032 ! melanosome localization GO:0032400 16 10 0,000 0,02981234 0,05634603 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02981234 0,0563018 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02981234 0,05625764 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02981234 0,05621355 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02981234 0,05616953 ! mRNA cleavage GO:0006379 17 10 0,000 0,02981234 0,05612558 ! protein sumoylation GO:0016925 15 10 0,000 0,02981234 0,0560817 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02981234 0,05603788 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02981234 0,05599414 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02981234 0,05595046 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02981234 0,05590685 ! prophase GO:0051324 15 10 0,000 0,02981234 0,05586331 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02981234 0,05581984 ! apical protein localization GO:0045176 15 10 0,000 0,02981234 0,05577643 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02981234 0,05573309 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 13 10 0,000 0,02981234 0,05568982 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02981234 0,05564662 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02981234 0,05560348 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02981234 0,05556041 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02981234 0,05551741 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02981234 0,05547447 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02981234 0,0554316 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02981234 0,0553888 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02981234 0,05534606 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02981234 0,05530339 ! oocyte development GO:0048599 17 10 0,000 0,02981234 0,05526078 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02981234 0,05521824 ! blastocyst formation GO:0001825 17 10 0,000 0,02981234 0,05517576 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02981234 0,05513335 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02981234 0,05509101 ! activation of innate immune response GO:0002218 12 10 0,000 0,02981234 0,05504873 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02981234 0,05500651 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02981234 0,05496436 ! response to nicotine GO:0035094 20 10 0,000 0,02981234 0,05492228 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02981234 0,05488025 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02981234 0,0548383 ! localization within membrane GO:0051668 20 10 0,000 0,02981234 0,0547964 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,02983492 0,05479604 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,02983492 0,05475424 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,03045405 0,05584791 ! sex differentiation GO:0007548 145 90 1,000 0,03045405 0,05580537 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,03045405 0,0557629 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,03234193 0,05917466 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,03234193 0,0591297 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03274478 0,05982077 ! respiratory burst GO:0045730 17 11 0,000 0,03274478 0,05977538 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03274478 0,05973006 ! neuron fate specification GO:0048665 17 11 0,000 0,03274478 0,05968481 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03274478 0,05963963 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03274478 0,05959452 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03274478 0,05954947 ! thyroid gland development GO:0030878 26 11 0,000 0,03274478 0,05950449 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,03274478 0,05945959 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03274478 0,05941474 ! response to pain GO:0048265 24 11 0,000 0,03274478 0,05936997 ! T cell proliferation GO:0042098 26 11 0,000 0,03274478 0,05932526 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03274478 0,05928063 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03274478 0,05923605 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03274478 0,05919155 ! bone resorption GO:0045453 16 11 0,000 0,03274478 0,05914711 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03274478 0,05910274 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03274478 0,05905843 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03274478 0,0590142 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03274478 0,05897002 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03274478 0,05892592 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03274478 0,05888188 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03274478 0,0588379 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03274478 0,05879399 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,03274478 0,05875015 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03274478 0,05870637 ! UV protection GO:0009650 19 11 0,000 0,03274478 0,05866266 ! adult heart development GO:0007512 14 11 0,000 0,03274478 0,05861901 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03274478 0,05857543 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03274478 0,05853191 ! temperature homeostasis GO:0001659 17 11 0,000 0,03274478 0,05848846 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03274478 0,05844507 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03274478 0,05840174 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03274478 0,05835848 ! regulation of organ growth GO:0046620 13 11 0,000 0,03274478 0,05831529 ! pigment granule localization GO:0051875 20 11 0,000 0,03274478 0,05827215 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03274478 0,05822908 ! vasoconstriction GO:0042310 18 11 0,000 0,03274478 0,05818608 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03274478 0,05814314 ! embryonic axis specification GO:0000578 18 11 0,000 0,03274478 0,05810026 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03274478 0,05805744 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03274478 0,05801469 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03274478 0,057972 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03274478 0,05792938 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03274478 0,05788681 ! zymogen activation GO:0031638 15 11 0,000 0,03274478 0,05784431 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03274478 0,05780187 ! nucleosome positioning GO:0016584 15 11 0,000 0,03274478 0,0577595 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03274478 0,05771718 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03274478 0,05767493 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03274478 0,05763274 ! acid secretion GO:0046717 18 11 0,000 0,03274478 0,05759061 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03274478 0,05754854 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03274478 0,05750653 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03274478 0,05746459 ! oocyte differentiation GO:0009994 18 11 0,000 0,03274478 0,05742271 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03274478 0,05738088 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03274478 0,05733912 ! cholesterol efflux GO:0033344 19 11 0,000 0,03274478 0,05729742 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03274478 0,05725578 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03274478 0,0572142 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03274478 0,05717268 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 15 11 0,000 0,03274478 0,05713122 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03274478 0,05708982 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03274478 0,05704848 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03274478 0,0570072 ! defense response to fungus GO:0050832 13 11 0,000 0,03274478 0,05696598 ! developmental induction GO:0031128 19 11 0,000 0,03274478 0,05692482 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03274478 0,05688372 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03274478 0,05684268 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03274478 0,0568017 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03274478 0,05676077 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03274478 0,05671991 ! regulation of embryonic development GO:0045995 27 11 0,000 0,03274478 0,0566791 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03274478 0,05663835 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,03298126 0,05700639 ! transcription initiation GO:0006352 153 94 1,000 0,03298126 0,05696547 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03298126 0,05692461 ! forebrain development GO:0030900 188 95 1,000 0,03362554 0,05799502 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,03362554 0,05795348 ! detection of stimulus GO:0051606 151 96 1,000 0,03427475 0,0590301 ! response to virus GO:0009615 160 98 1,000 0,0355878 0,06124768 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03566846 0,06134262 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03566846 0,0612988 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03566846 0,06125505 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,03566846 0,06121135 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03566846 0,06116773 ! virus-host interaction GO:0019048 29 12 0,000 0,03566846 0,06112416 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03566846 0,06108065 ! cartilage condensation GO:0001502 20 12 0,000 0,03566846 0,06103721 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03566846 0,06099383 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03566846 0,06095051 ! protein complex disassembly GO:0043241 27 12 0,000 0,03566846 0,06090725 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03566846 0,06086406 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03566846 0,06082092 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03566846 0,06077785 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03566846 0,06073483 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03566846 0,06069188 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03566846 0,06064899 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03566846 0,06060616 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03566846 0,06056339 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03566846 0,06052068 ! drug transport GO:0015893 16 12 0,000 0,03566846 0,06047803 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03566846 0,06043544 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03566846 0,06039291 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03566846 0,06035044 ! focal adhesion formation GO:0048041 35 12 0,000 0,03566846 0,06030802 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03566846 0,06026567 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03566846 0,06022338 ! forebrain cell migration GO:0021885 21 12 0,000 0,03566846 0,06018115 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03566846 0,06013898 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03566846 0,06009686 ! fear response GO:0042596 26 12 0,000 0,03566846 0,06005481 ! monoamine transport GO:0015844 18 12 0,000 0,03566846 0,06001281 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03566846 0,05997087 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03566846 0,05992899 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03566846 0,05988717 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03566846 0,05984541 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03566846 0,05980371 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03566846 0,05976206 ! protein homotetramerization GO:0051289 21 12 0,000 0,03566846 0,05972047 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03566846 0,05967894 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03566846 0,05963747 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03566846 0,05959605 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03566846 0,0595547 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03566846 0,0595134 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03566846 0,05947215 ! cranial nerve development GO:0021545 20 12 0,000 0,03566846 0,05943097 ! fucose catabolic process GO:0019317 22 12 0,000 0,03566846 0,05938984 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03566846 0,05934877 ! histone methylation GO:0016571 26 12 0,000 0,03566846 0,05930775 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03566846 0,05926679 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03566846 0,05922589 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03566846 0,05918505 ! T cell homeostasis GO:0043029 25 12 0,000 0,03566846 0,05914426 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03566846 0,05910353 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03566846 0,05906285 ! spleen development GO:0048536 22 12 0,000 0,03566846 0,05902223 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03566846 0,05898166 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03566846 0,05894115 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03566846 0,0589007 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03566846 0,0588603 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03566846 0,05881996 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,03566846 0,05877967 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03566846 0,05873944 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03566846 0,05869926 ! response to cold GO:0009409 17 12 0,000 0,03566846 0,05865914 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03566846 0,05861907 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03566846 0,05857906 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,03625157 0,0594961 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0385834 0,06327993 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,0385834 0,06323682 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,0385834 0,06319378 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,0385834 0,06315079 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,0385834 0,06310786 ! lipid localization GO:0010876 28 13 0,000 0,0385834 0,06306498 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,0385834 0,06302217 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,0385834 0,06297941 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,0385834 0,06293672 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,0385834 0,06289408 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,0385834 0,06285149 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,0385834 0,06280897 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,0385834 0,0627665 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0385834 0,06272409 ! methionine metabolic process GO:0006555 27 13 0,000 0,0385834 0,06268174 ! plasma membrane organization GO:0007009 24 13 0,000 0,0385834 0,06263944 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,0385834 0,06259721 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,0385834 0,06255502 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,0385834 0,0625129 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,0385834 0,06247083 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,0385834 0,06242882 ! response to X-ray GO:0010165 25 13 0,000 0,0385834 0,06238687 ! cytokine metabolic process GO:0042107 22 13 0,000 0,0385834 0,06234497 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,0385834 0,06230313 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,0385834 0,06226134 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,0385834 0,06221961 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,0385834 0,06217793 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,0385834 0,06213632 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,0385834 0,06209475 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,0385834 0,06205325 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,0385834 0,06201179 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,0385834 0,0619704 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,0385834 0,06192906 ! regulation of cellular pH GO:0030641 22 13 0,000 0,0385834 0,06188777 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0385834 0,06184654 ! ribosome assembly GO:0042255 17 13 0,000 0,0385834 0,06180536 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,0385834 0,06176424 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,0385834 0,06172318 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,0385834 0,06168216 ! regulation of epidermis development GO:0045682 19 13 0,000 0,0385834 0,06164121 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,0385834 0,0616003 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,0385834 0,06155945 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,0385834 0,06151866 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0385834 0,06147792 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,0385834 0,06143723 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,0385834 0,0613966 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,0385834 0,06135602 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,0385834 0,06131549 ! embryonic placenta development GO:0001892 23 13 0,000 0,0385834 0,06127502 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,0385834 0,0612346 ! insulin secretion GO:0030073 23 13 0,000 0,0385834 0,06119424 ! actin filament polymerization GO:0030041 24 13 0,000 0,0385834 0,06115392 ! acrosome reaction GO:0007340 18 13 0,000 0,0385834 0,06111366 ! rRNA transcription GO:0009303 25 14 0,000 0,04148962 0,0656737 ! lactation GO:0007595 26 14 0,000 0,04148962 0,06563052 ! reproductive cellular process GO:0048610 20 14 0,000 0,04148962 0,0655874 ! tRNA modification GO:0006400 20 14 0,000 0,04148962 0,06554434 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04148962 0,06550133 ! regulation of S phase GO:0033261 23 14 0,000 0,04148962 0,06545838 ! water transport GO:0006833 21 14 0,000 0,04148962 0,06541548 GO:0042044|fluid transport, ! non-recombinational repair GO:0000726 25 14 0,000 0,04148962 0,06537264 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04148962 0,06532986 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04148962 0,06528713 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04148962 0,06524446 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04148962 0,06520185 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04148962 0,06515929 ! palate development GO:0060021 31 14 0,000 0,04148962 0,06511678 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04148962 0,06507433 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04148962 0,06503194 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04148962 0,0649896 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04148962 0,06494732 ! arginine metabolic process GO:0006525 17 14 0,000 0,04148962 0,06490509 ! regulation of heart rate GO:0002027 24 14 0,000 0,04148962 0,06486292 ! organic alcohol transport GO:0015850 29 14 0,000 0,04148962 0,0648208 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04148962 0,06477873 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04148962 0,06473672 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04148962 0,06469477 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04148962 0,06465287 ! L-amino acid transport GO:0015807 30 14 0,000 0,04148962 0,06461102 ! bone mineralization GO:0030282 17 14 0,000 0,04148962 0,06456923 ! stem cell development GO:0048864 43 14 0,000 0,04148962 0,06452749 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04148962 0,06448581 ! cerebellum development GO:0021549 21 14 0,000 0,04148962 0,06444417 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04148962 0,0644026 ! response to gamma radiation GO:0010332 28 14 0,000 0,04148962 0,06436107 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04148962 0,0643196 ! cofactor transport GO:0051181 26 14 0,000 0,04148962 0,06427819 ! NADP metabolic process GO:0006739 24 14 0,000 0,04148962 0,06423683 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04148962 0,06419552 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04148962 0,06415426 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04148962 0,06411306 ! oxygen transport GO:0015671 21 14 0,000 0,04148962 0,0640719 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04148962 0,06403081 ! male genitalia development GO:0030539 24 14 0,000 0,04148962 0,06398976 ! regulation of axon extension GO:0030516 37 14 0,000 0,04148962 0,06394877 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04148962 0,06390783 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04438715 0,06832725 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04438715 0,06828356 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04438715 0,06823993 ! superoxide anion generation GO:0042554 20 15 0,000 0,04438715 0,06819635 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04438715 0,06815283 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04438715 0,06810937 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04438715 0,06806596 ! copper ion transport GO:0006825 20 15 0,000 0,04438715 0,06802261 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04438715 0,06797931 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04438715 0,06793606 ! sulfate transport GO:0008272 23 15 0,000 0,04438715 0,06789287 ! response to cAMP GO:0051591 22 15 0,000 0,04438715 0,06784974 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04438715 0,06780666 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04438715 0,06776364 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04438715 0,06772067 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! response to hexose stimulus GO:0009746 22 15 0,000 0,04438715 0,06767775 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04438715 0,06763489 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04438715 0,06759208 ! pituitary gland development GO:0021983 29 15 0,000 0,04438715 0,06754933 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04438715 0,06750663 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04438715 0,06746399 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,04438715 0,0674214 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04438715 0,06737886 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,04438715 0,06733638 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04438715 0,06729395 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04438715 0,06725157 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04438715 0,06720925 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04438715 0,06716698 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04438715 0,06712476 ! histone deacetylation GO:0016575 20 15 0,000 0,04438715 0,0670826 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04438715 0,06704048 ! tissue regeneration GO:0042246 26 15 0,000 0,04438715 0,06699843 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04438715 0,06695642 ! water homeostasis GO:0030104 27 15 0,000 0,04438715 0,06691447 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04438715 0,06687257 ! muscle maintenance GO:0046716 26 15 0,000 0,04438715 0,06683072 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04438715 0,06678893 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04438715 0,06674718 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04438715 0,06670549 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04438715 0,06666385 ! cell killing GO:0001906 29 15 0,000 0,04438715 0,06662227 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04438715 0,06658073 ! detection of bacterium GO:0016045 18 15 0,000 0,04438715 0,06653925 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04438715 0,06649782 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04438715 0,06645644 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04438715 0,06641511 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04438715 0,06637383 ! peptide hormone processing GO:0016486 23 15 0,000 0,04438715 0,0663326 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04727602 0,07060591 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,04727602 0,07056211 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04727602 0,07051836 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04727602 0,07047467 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04727602 0,07043103 ! bone remodeling GO:0046849 27 16 0,000 0,04727602 0,07038745 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04727602 0,07034392 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04727602 0,07030044 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04727602 0,07025702 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04727602 0,07021365 ! startle response GO:0001964 28 16 0,000 0,04727602 0,07017034 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04727602 0,07012707 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04727602 0,07008387 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04727602 0,07004071 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04727602 0,06999761 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04727602 0,06995456 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04727602 0,06991156 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04727602 0,06986862 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04727602 0,06982573 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04727602 0,06978289 ! response to osmotic stress GO:0006970 25 16 0,000 0,04727602 0,06974011 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04727602 0,06969737 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04727602 0,06965469 ! fructose metabolic process GO:0006000 25 16 0,000 0,04727602 0,06961206 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04727602 0,06956949 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04727602 0,06952696 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04727602 0,06948449 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04727602 0,06944207 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04727602 0,0693997 ! axon cargo transport GO:0008088 43 16 0,000 0,04727602 0,06935739 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04727602 0,06931512 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04727602 0,06927291 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04727602 0,06923074 ! neuron recognition GO:0008038 35 16 0,000 0,04727602 0,06918863 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04727602 0,06914657 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04727602 0,06910456 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04727602 0,06906261 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04727602 0,0690207 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04727602 0,06897884 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04727602 0,06893704 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04727602 0,06889528 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04727602 0,06885358 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04727602 0,06881193 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,04727602 0,06877032 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04727602 0,06872877 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05015626 0,07287195 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05015626 0,07282797 ! metencephalon development GO:0022037 30 17 0,000 0,05015626 0,07278405 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05015626 0,07274018 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05015626 0,07269636 ! signal complex assembly GO:0007172 41 17 0,000 0,05015626 0,07265259 ! inositol metabolic process GO:0006020 28 17 0,000 0,05015626 0,07260888 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05015626 0,07256522 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05015626 0,07252161 ! glial cell development GO:0021782 27 17 0,000 0,05015626 0,07247805 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05015626 0,07243455 ! adult walking behavior GO:0007628 33 17 0,000 0,05015626 0,07239109 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05015626 0,07234769 ! heart looping GO:0001947 30 17 0,000 0,05015626 0,07230435 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05015626 0,07226105 ! myoblast differentiation GO:0045445 45 17 0,000 0,05015626 0,07221781 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05015626 0,07217461 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,05015626 0,07213147 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05015626 0,07208838 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05015626 0,07204535 ! glycine metabolic process GO:0006544 28 17 0,000 0,05015626 0,07200236 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,05015626 0,07195942 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05015626 0,07191654 ! NAD metabolic process GO:0019674 29 17 0,000 0,05015626 0,07187371 ! DNA integration GO:0015074 29 17 0,000 0,05015626 0,07183092 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05015626 0,07178819 ! regulation of protein binding GO:0043393 33 17 0,000 0,05015626 0,07174551 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05015626 0,07170288 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05015626 0,0716603 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05015626 0,07161778 ! genitalia development GO:0048806 30 17 0,000 0,05015626 0,0715753 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05015626 0,07153287 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05015626 0,07149049 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05015626 0,07144817 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05015626 0,07140589 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05015626 0,07136366 ! steroid catabolic process GO:0006706 31 17 0,000 0,05015626 0,07132149 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05015626 0,07127936 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05015626 0,07123728 ! gas transport GO:0015669 25 17 0,000 0,05015626 0,07119525 ! organic cation transport GO:0015695 31 17 0,000 0,05015626 0,07115327 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05015626 0,07111135 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05015626 0,07106947 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05015626 0,07102764 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05015626 0,07098585 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05015626 0,07094412 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05302788 0,07496185 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05302788 0,07491783 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05302788 0,07487387 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05302788 0,07482995 ! memory GO:0007613 31 18 0,000 0,05302788 0,07478609 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05302788 0,07474228 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05302788 0,07469852 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05302788 0,07465481 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05302788 0,07461115 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,05302788 0,07456755 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05302788 0,07452399 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05302788 0,07448049 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05302788 0,07443703 ! response to retinoic acid GO:0032526 26 18 0,000 0,05302788 0,07439363 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05302788 0,07435028 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05302788 0,07430697 ! response to fungus GO:0009620 21 18 0,000 0,05302788 0,07426372 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05302788 0,07422052 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05302788 0,07417737 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05302788 0,07413427 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05302788 0,07409122 ! vitamin transport GO:0051180 27 18 0,000 0,05302788 0,07404821 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05302788 0,07400526 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05302788 0,07396236 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05302788 0,07391951 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,05302788 0,07387671 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05302788 0,07383395 ! nerve development GO:0021675 28 18 0,000 0,05302788 0,07379125 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05302788 0,0737486 ! protein secretion GO:0009306 39 19 0,000 0,05589091 0,07768546 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05589091 0,07764061 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05589091 0,07759581 ! skin development GO:0043588 36 19 0,000 0,05589091 0,07755106 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05589091 0,07750636 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05589091 0,07746171 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05589091 0,07741712 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05589091 0,07737257 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05589091 0,07732808 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,05589091 0,07728364 ! cerebral cortex development GO:0021987 36 19 0,000 0,05589091 0,07723925 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05589091 0,07719491 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05589091 0,07715062 ! heme metabolic process GO:0042168 36 19 0,000 0,05589091 0,07710638 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05589091 0,0770622 ! neuromuscular junction development GO:0007528 34 19 0,000 0,05589091 0,07701806 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05589091 0,07697397 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,05589091 0,07692994 ! protein export from nucleus GO:0006611 36 19 0,000 0,05589091 0,07688595 ! heart process GO:0003015 30 19 0,000 0,05589091 0,07684202 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05589091 0,07679813 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05589091 0,0767543 ! cellular pigmentation GO:0033059 36 19 0,000 0,05589091 0,07671051 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05589091 0,07666678 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05589091 0,0766231 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05589091 0,07657946 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05589091 0,07653587 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05589091 0,07649234 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05589091 0,07644885 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05589091 0,07640542 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05589091 0,07636203 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05589091 0,07631869 ! cilium assembly GO:0042384 37 19 0,000 0,05589091 0,0762754 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05874538 0,08012551 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,05874538 0,08008011 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05874538 0,08003476 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05874538 0,07998947 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05874538 0,07994423 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,05874538 0,07989904 ! cAMP metabolic process GO:0046058 36 20 0,000 0,05874538 0,0798539 ! response to vitamin GO:0033273 31 20 0,000 0,05874538 0,07980881 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05874538 0,07976377 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,05874538 0,07971878 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05874538 0,07967384 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05874538 0,07962895 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05874538 0,07958412 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05874538 0,07953933 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05874538 0,0794946 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05874538 0,07944991 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,05874538 0,07940528 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,05874538 0,07936069 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05874538 0,07931616 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05874538 0,07927167 ! body fluid secretion GO:0007589 31 20 0,000 0,05874538 0,07922724 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05874538 0,07918285 ! stem cell differentiation GO:0048863 53 20 0,000 0,05874538 0,07913852 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05874538 0,07909423 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05874538 0,07905 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05874538 0,07900581 ! sensory perception of pain GO:0019233 30 20 0,000 0,05874538 0,07896167 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05874538 0,07891758 ! diencephalon development GO:0021536 34 20 0,000 0,05874538 0,07887355 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05874538 0,07882956 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05874538 0,07878562 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05874538 0,07874172 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,05874538 0,07869788 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05874538 0,07865409 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05874538 0,07861034 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05874538 0,07856664 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05874538 0,078523 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05874538 0,0784794 ! regulation of glucose import GO:0046324 29 20 0,000 0,05874538 0,07843585 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,05874538 0,07839234 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05874538 0,07834889 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,05874538 0,07830548 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05874538 0,07826212 ! negative regulation of translation GO:0017148 29 20 0,000 0,05874538 0,07821881 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05874538 0,07817555 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,05874538 0,07813234 ! regulation of cell killing GO:0031341 42 21 0,000 0,06159132 0,08187222 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06159132 0,08182701 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06159132 0,08178185 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06159132 0,08173675 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06159132 0,08169169 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06159132 0,08164668 ! axis specification GO:0009798 38 21 0,000 0,06159132 0,08160172 ! ovarian follicle development GO:0001541 35 21 0,000 0,06159132 0,08155681 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06159132 0,08151195 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06159132 0,08146714 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06159132 0,08142237 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06159132 0,08137766 ! cell aging GO:0007569 44 21 0,000 0,06159132 0,081333 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06159132 0,08128838 ! cytolysis GO:0019835 24 21 0,000 0,06159132 0,08124382 ! vasodilation GO:0042311 39 21 0,000 0,06159132 0,0811993 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06159132 0,08115483 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06159132 0,08111041 ! oogenesis GO:0048477 36 21 0,000 0,06159132 0,08106604 ! collagen fibril organization GO:0030199 59 21 0,000 0,06159132 0,08102172 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06159132 0,08097744 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06159132 0,08093322 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06159132 0,08088904 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06159132 0,08084491 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06159132 0,08080083 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06159132 0,0807568 ! collagen catabolic process GO:0030574 28 21 0,000 0,06159132 0,08071281 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06159132 0,08066887 ! gut development GO:0048565 39 21 0,000 0,06159132 0,08062498 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06442875 0,0842934 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06442875 0,08424759 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06442875 0,08420183 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06442875 0,08415612 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06442875 0,08411045 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06442875 0,08406484 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06442875 0,08401928 ! regeneration GO:0031099 41 22 0,000 0,06442875 0,08397376 ! keratinization GO:0031424 28 22 0,000 0,06442875 0,0839283 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06442875 0,08388288 ! sensory perception of taste GO:0050909 28 22 0,000 0,06442875 0,08383752 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,06442875 0,0837922 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06442875 0,08374693 ! vacuolar transport GO:0007034 36 22 0,000 0,06442875 0,08370171 ! lysosome organization GO:0007040 41 22 0,000 0,06442875 0,08365654 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06442875 0,08361142 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06442875 0,08356634 ! fucose metabolic process GO:0006004 39 22 0,000 0,06442875 0,08352132 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06442875 0,08347634 ! ureteric bud development GO:0001657 43 22 0,000 0,06442875 0,08343141 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06442875 0,08338653 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06442875 0,0833417 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06442875 0,08329692 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,06442875 0,08325218 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06442875 0,0832075 ! sarcomere organization GO:0045214 30 22 0,000 0,06442875 0,08316286 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06442875 0,08311827 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06442875 0,08307372 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06442875 0,08302923 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,06442875 0,08298478 ! protein stabilization GO:0050821 39 22 0,000 0,06442875 0,08294038 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,06725769 0,08653583 ! gluconeogenesis GO:0006094 33 23 0,000 0,06725769 0,08648958 ! viral genome replication GO:0019079 41 23 0,000 0,06725769 0,08644338 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06725769 0,08639722 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06725769 0,08635112 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06725769 0,08630507 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06725769 0,08625906 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06725769 0,08621311 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06725769 0,0861672 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06725769 0,08612134 ! response to ethanol GO:0045471 46 23 0,000 0,06725769 0,08607553 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06725769 0,08602977 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,06725769 0,08598406 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06725769 0,0859384 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06725769 0,08589278 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,06725769 0,08584721 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,06725769 0,0858017 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06725769 0,08575623 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06725769 0,0857108 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06725769 0,08566543 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06725769 0,08562011 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06725769 0,08557483 ! fatty acid transport GO:0015908 44 23 0,000 0,06725769 0,0855296 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06725769 0,08548442 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06725769 0,08543928 ! cell-cell recognition GO:0009988 25 23 0,000 0,06725769 0,0853942 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06725769 0,08534916 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06725769 0,08530416 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,06725769 0,08525922 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06725769 0,08521432 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,07007817 0,08874109 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07007817 0,08869441 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,07007817 0,08864778 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07007817 0,0886012 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07007817 0,08855466 ! vesicle docking GO:0048278 47 24 0,000 0,07007817 0,08850818 ! spinal cord development GO:0021510 47 24 0,000 0,07007817 0,08846174 ! vacuole organization GO:0007033 43 24 0,000 0,07007817 0,08841535 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07007817 0,08836901 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07007817 0,08832272 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07007817 0,08827648 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07007817 0,08823029 ! membrane depolarization GO:0051899 39 24 0,000 0,07007817 0,08818414 ! pentose metabolic process GO:0019321 35 24 0,000 0,07007817 0,08813804 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,07007817 0,08809199 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07007817 0,08804599 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07007817 0,08800004 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07007817 0,08795413 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07007817 0,08790828 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07007817 0,08786247 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07007817 0,08781671 ! regulation of amine transport GO:0051952 40 24 0,000 0,07007817 0,08777099 ! protein tetramerization GO:0051262 52 24 0,000 0,07007817 0,08772533 ! myelination GO:0042552 45 25 0,000 0,07289022 0,09119805 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07289022 0,09115065 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07289022 0,0911033 ! phototransduction GO:0007602 33 25 0,000 0,07289022 0,091056 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07289022 0,09100875 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,07289022 0,09096154 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,07289022 0,09091439 ! sperm motility GO:0030317 31 25 0,000 0,07289022 0,09086728 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07289022 0,09082023 ! receptor metabolic process GO:0043112 46 25 0,000 0,07289022 0,09077322 ! response to starvation GO:0042594 42 25 0,000 0,07289022 0,09072626 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07289022 0,09067935 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,07289022 0,09063248 ! neural crest cell development GO:0014032 54 25 0,000 0,07289022 0,09058567 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07289022 0,0905389 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,07289022 0,09049219 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07289022 0,09044552 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07289022 0,0903989 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,07289022 0,09035232 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07289022 0,0903058 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,07289022 0,09025932 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07289022 0,09021289 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07289022 0,09016651 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,07289022 0,09012017 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07289022 0,09007389 ! telomere organization GO:0032200 43 25 0,000 0,07289022 0,09002765 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07289022 0,08998146 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07289022 0,08993531 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07569385 0,0933467 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07569385 0,09329888 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07569385 0,0932511 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07569385 0,09320338 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07569385 0,09315571 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07569385 0,09310808 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07569385 0,0930605 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07569385 0,09301297 ! molting cycle process GO:0022404 50 26 0,000 0,07569385 0,09296549 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07569385 0,09291806 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07569385 0,09287068 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,07569385 0,09282335 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,07569385 0,09277606 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07569385 0,09272882 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07569385 0,09268163 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07569385 0,09263449 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07569385 0,09258739 ! blastocyst development GO:0001824 49 26 0,000 0,07569385 0,09254035 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07569385 0,09249335 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07569385 0,0924464 ! neuron fate commitment GO:0048663 48 27 0,000 0,0784891 0,09581166 ! iron ion transport GO:0006826 59 27 0,000 0,0784891 0,09576307 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,0784891 0,09571453 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0784891 0,09566605 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0784891 0,09561761 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0784891 0,09556922 ! fat cell differentiation GO:0045444 50 27 0,000 0,0784891 0,09552088 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0784891 0,09547259 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0784891 0,09542434 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0784891 0,09537615 ! autophagy GO:0006914 41 27 0,000 0,0784891 0,095328 ! male gonad development GO:0008584 44 27 0,000 0,0784891 0,09527991 ! response to toxin GO:0009636 47 27 0,000 0,0784891 0,09523186 ! primary neural tube formation GO:0014020 51 27 0,000 0,0784891 0,09518386 ! base-excision repair GO:0006284 41 27 0,000 0,0784891 0,09513591 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0784891 0,095088 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0784891 0,09504015 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0784891 0,09499234 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0784891 0,09494458 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0784891 0,09489687 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,0784891 0,09484921 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08127599 0,09816769 ! circadian rhythm GO:0007623 50 28 0,000 0,08127599 0,09811843 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08127599 0,09806922 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,08127599 0,09802007 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,08127599 0,09797096 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08127599 0,0979219 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,08127599 0,09787289 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08127599 0,09782393 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08127599 0,09777502 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08127599 0,09772615 ! synaptogenesis GO:0007416 42 28 0,000 0,08127599 0,09767734 ! lipid oxidation GO:0034440 43 28 0,000 0,08127599 0,09762857 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08127599 0,09757986 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08127599 0,09753119 ! translational initiation GO:0006413 65 29 0,000 0,08405454 0,10081517 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08405454 0,10076494 ! regulation of pH GO:0006885 43 29 0,000 0,08405454 0,10071476 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08405454 0,10066462 ! catechol metabolic process GO:0009712 54 29 0,000 0,08405454 0,10061454 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08405454 0,10056451 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08405454 0,10051453 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08405454 0,10046459 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08405454 0,10041471 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08405454 0,10036488 ! cell fate determination GO:0001709 60 29 0,000 0,08405454 0,10031509 ! detection of light stimulus GO:0009583 38 29 0,000 0,08405454 0,10026536 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,08405454 0,10021567 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08405454 0,10016604 ! tissue homeostasis GO:0001894 48 29 0,000 0,08405454 0,10011645 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,08405454 0,10006691 ! phenol metabolic process GO:0018958 55 30 0,000 0,08682478 0,10331376 ! zinc ion transport GO:0006829 45 30 0,000 0,08682478 0,10326269 ! membrane docking GO:0022406 61 30 0,000 0,08682478 0,10321168 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08682478 0,10316071 ! cell junction assembly GO:0034329 78 30 0,000 0,08682478 0,10310979 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08682478 0,10305892 ! myofibril assembly GO:0030239 47 30 0,000 0,08682478 0,1030081 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,08682478 0,10295733 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,08682478 0,10290662 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,08682478 0,10285595 ! phospholipid transport GO:0015914 51 30 0,000 0,08682478 0,10280533 ! ensheathment of neurons GO:0007272 57 30 0,000 0,08682478 0,10275476 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,08682478 0,10270424 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08682478 0,10265377 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,08682478 0,10260336 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,08682478 0,10255299 ! eye morphogenesis GO:0048592 60 30 0,000 0,08682478 0,10250266 ! response to heat GO:0009408 50 30 0,000 0,08682478 0,10245239 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,08958674 0,10565965 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,08958674 0,10560789 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,08958674 0,10555617 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,08958674 0,1055045 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,08958674 0,10545288 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,08958674 0,10540132 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,08958674 0,1053498 ! ovulation cycle process GO:0022602 49 31 0,000 0,08958674 0,10529834 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,08958674 0,10524692 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,08958674 0,10519556 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,08958674 0,10514424 ! mesoderm formation GO:0001707 69 31 0,000 0,08958674 0,10509298 ! natural killer cell activation GO:0030101 45 31 0,000 0,08958674 0,10504176 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,08958674 0,1049906 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,08958674 0,10493948 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,08958674 0,10488842 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09234043 0,10805986 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09234043 0,10800733 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09234043 0,10795485 ! spliceosome assembly GO:0000245 67 32 0,000 0,09234043 0,10790242 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09234043 0,10785004 ! metanephros development GO:0001656 74 32 0,000 0,09234043 0,10779771 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09234043 0,10774543 ! response to ionizing radiation GO:0010212 65 32 0,000 0,09234043 0,1076932 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,09234043 0,10764103 ! muscle cell development GO:0055001 49 32 0,000 0,09234043 0,1075889 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,09234043 0,10753683 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09234043 0,1074848 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09234043 0,10743282 ! ovulation cycle GO:0042698 51 32 0,000 0,09234043 0,1073809 ! peripheral nervous system development GO:0007422 64 32 0,000 0,09234043 0,10732902 ! BMP signaling pathway GO:0030509 64 32 0,000 0,09234043 0,1072772 ! hindbrain development GO:0030902 61 32 0,000 0,09234043 0,10722542 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09234043 0,1071737 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,09234043 0,10712203 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,09508589 0,11025381 ! post-embryonic development GO:0009791 69 33 0,000 0,09508589 0,1102007 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,09508589 0,11014764 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09508589 0,11009463 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,09508589 0,11004168 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09508589 0,10998877 ! formation of primary germ layer GO:0001704 72 33 0,000 0,09508589 0,10993592 ! cell fate specification GO:0001708 52 33 0,000 0,09508589 0,10988312 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09508589 0,10983036 ! adult locomotory behavior GO:0008344 59 33 0,000 0,09508589 0,10977766 ! glial cell differentiation GO:0010001 63 34 0,000 0,09782313 0,11288367 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,09782313 0,11282955 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,09782313 0,11277549 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,09782313 0,11272148 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,09782313 0,11266752 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,09782313 0,11261361 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,09782313 0,11255976 ! mismatch repair GO:0006298 46 34 0,000 0,09782313 0,11250595 ! spermatid development GO:0007286 63 34 0,000 0,09782313 0,1124522 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,09782313 0,1123985 ! placenta development GO:0001890 53 34 0,000 0,09782313 0,11234484 ! regulation of muscle development GO:0048634 70 35 0,000 0,10055218 0,11542393 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10055218 0,11536888 ! odontogenesis GO:0042476 66 35 0,000 0,10055218 0,11531389 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10055218 0,11525896 ! female gonad development GO:0008585 58 35 0,000 0,10055218 0,11520407 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10055218 0,11514924 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,10055218 0,11509446 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,10055218 0,11503973 ! cytokine production GO:0001816 59 35 0,000 0,10055218 0,11498505 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,10055218 0,11493043 ! neural tube formation GO:0001841 67 35 0,000 0,10055218 0,11487586 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,10327307 0,11792834 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10327307 0,11787239 ! cell junction organization GO:0034330 86 36 0,000 0,10327307 0,1178165 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10327307 0,11776067 ! positive regulation of cell development GO:0010720 80 36 0,000 0,10327307 0,11770488 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10327307 0,11764915 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10327307 0,11759347 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10327307 0,11753785 ! aerobic respiration GO:0009060 55 36 0,000 0,10327307 0,11748227 ! embryonic organ development GO:0048568 57 36 0,000 0,10327307 0,11742675 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10327307 0,11737128 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,10327307 0,11731587 ! RNA export from nucleus GO:0006405 56 37 0,000 0,10598582 0,12034067 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,10598582 0,1202839 ! actomyosin structure organization GO:0031032 62 37 0,000 0,10598582 0,12022719 ! organic anion transport GO:0015711 68 37 0,000 0,10598582 0,12017054 ! tissue remodeling GO:0048771 76 37 0,000 0,10598582 0,12011393 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,10598582 0,12005738 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,10598582 0,12000088 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,10598582 0,11994444 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,10598582 0,11988805 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,10598582 0,11983171 ! glycogen metabolic process GO:0005977 61 37 0,000 0,10598582 0,11977542 ! pigment metabolic process GO:0042440 80 37 0,000 0,10598582 0,11971919 ! spermatid differentiation GO:0048515 66 37 0,000 0,10598582 0,11966301 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,10869045 0,12265911 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,10869045 0,1226016 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,10869045 0,12254415 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,10869045 0,12248675 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,10869045 0,12242941 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,10869045 0,12237212 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,10869045 0,12231488 GO:0046660|female sex differentiation, ! nucleotide catabolic process GO:0009166 61 38 0,000 0,10869045 0,1222577 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,10869045 0,12220057 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,10869045 0,12214349 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,10869045 0,12208647 ! glucan metabolic process GO:0044042 62 38 0,000 0,10869045 0,1220295 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,11138699 0,12499864 ! mammary gland development GO:0030879 86 39 0,000 0,11138699 0,12494037 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11138699 0,12488215 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11138699 0,12482398 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11138699 0,12476587 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11138699 0,12470781 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,11138699 0,12464981 ! RNA modification GO:0009451 57 39 0,000 0,11138699 0,12459186 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11138699 0,12453396 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11407546 0,12748051 ! feeding behavior GO:0007631 59 40 0,000 0,11407546 0,12742133 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,11407546 0,1273622 ! mesenchymal cell development GO:0014031 87 40 0,000 0,11407546 0,12730313 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,11675588 0,13023396 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,11675588 0,13017361 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,11675588 0,13011332 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,11675588 0,13005308 ! gliogenesis GO:0042063 88 41 0,000 0,11675588 0,1299929 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,11675588 0,12993277 ! T cell differentiation GO:0030217 81 41 0,000 0,11675588 0,1298727 ! female gamete generation GO:0007292 61 41 0,000 0,11675588 0,12981268 ! polyol metabolic process GO:0019751 66 41 0,000 0,11675588 0,12975272 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,11675588 0,12969282 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,11942828 0,13260012 ! regulation of tube size GO:0035150 71 42 0,000 0,11942828 0,13253895 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,11942828 0,13247785 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,11942828 0,1324168 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,11942828 0,1323558 ! neuron migration GO:0001764 79 42 0,000 0,11942828 0,13229487 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,11942828 0,13223399 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,12209269 0,1351219 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,12209269 0,13505978 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,12209269 0,13499771 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,12209269 0,1349357 ! glucose transport GO:0015758 65 43 0,000 0,12209269 0,13487374 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12209269 0,13481185 ! neural tube development GO:0021915 77 43 0,000 0,12209269 0,13475001 ! striated muscle contraction GO:0006941 77 43 0,000 0,12209269 0,13468822 ! phagocytosis GO:0006909 90 43 0,000 0,12209269 0,1346265 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12209269 0,13456483 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,12474912 0,13742967 ! hexose transport GO:0008645 67 44 0,000 0,12474912 0,13736677 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,12474912 0,13730393 ! male sex differentiation GO:0046661 76 44 0,000 0,12474912 0,13724115 ! double-strand break repair GO:0006302 81 44 0,000 0,12474912 0,13717842 ! B cell differentiation GO:0030183 107 44 0,000 0,12474912 0,13711576 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,12474912 0,13705315 ! developmental growth GO:0048589 82 44 0,000 0,12474912 0,13699059 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,12739761 0,13983515 ! glycolysis GO:0006096 65 45 0,000 0,12739761 0,13977138 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,12739761 0,13970768 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,12739761 0,13964403 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,12739761 0,13958044 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,12739761 0,13951691 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,12739761 0,13945343 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,12739761 0,13939001 ! cell growth GO:0016049 84 45 0,000 0,12739761 0,13932666 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13003816 0,14214985 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,13003816 0,1420853 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,13003816 0,1420208 ! response to calcium ion GO:0051592 81 47 0,000 0,13267082 0,1448303 ! endosome transport GO:0016197 108 47 0,000 0,13267082 0,14476462 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,13267082 0,144699 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,13267082 0,14463343 ! JNK cascade GO:0007254 91 47 0,000 0,13267082 0,14456793 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,13267082 0,14450248 ! protein homooligomerization GO:0051260 76 47 0,000 0,13267082 0,1444371 ! mitochondrial transport GO:0006839 82 48 0,000 0,13529559 0,14722804 ! Notch signaling pathway GO:0007219 96 48 0,000 0,13529559 0,14716148 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,13529559 0,14709498 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,13529559 0,14702854 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,13529559 0,14696216 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,13529559 0,14689584 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,13791251 0,1496696 ! regulation of action potential GO:0001508 95 49 0,000 0,13791251 0,14960212 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,13791251 0,1495347 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,13791251 0,14946734 ! regulation of ion transport GO:0043269 77 49 0,000 0,13791251 0,14940004 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,13791251 0,14933281 ! peptide metabolic process GO:0006518 76 49 0,000 0,13791251 0,14926563 ! response to temperature stimulus GO:0009266 76 49 0,000 0,13791251 0,14919851 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,13791251 0,14913146 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,13791251 0,14906446 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,13791251 0,14899753 ! neuromuscular process GO:0050905 99 50 0,000 0,14052159 0,15174818 ! inner ear development GO:0048839 79 50 0,000 0,14052159 0,15168011 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,14052159 0,15161209 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,14312287 0,15434945 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,14312287 0,1542803 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,14312287 0,15421121 ! excretion GO:0007588 83 51 0,000 0,14312287 0,15414218 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,14312287 0,15407321 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,14312287 0,1540043 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,14312287 0,15393546 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,14571636 0,15665485 ! positive regulation of growth GO:0045927 90 52 0,000 0,14571636 0,15658488 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,14571636 0,15651498 ! amino acid activation GO:0043038 92 52 0,000 0,14571636 0,15644514 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,14571636 0,15637536 ! synapse organization GO:0050808 85 52 0,000 0,14571636 0,15630564 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,14830208 0,15900838 ! RNA catabolic process GO:0006401 93 53 0,000 0,14830208 0,15893755 ! regulation of translational initiation GO:0006446 82 53 0,000 0,14830208 0,15886679 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,14830208 0,15879609 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,14830208 0,15872545 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,14830208 0,15865487 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,14830208 0,15858436 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,14830208 0,15851391 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,15088007 0,1611978 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,15088007 0,16112625 ! cell recognition GO:0008037 85 54 0,000 0,15088007 0,16105476 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,15088007 0,16098334 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,15088007 0,16091198 ! chloride transport GO:0006821 90 55 0,000 0,15345033 0,16358064 ! glucose catabolic process GO:0006007 82 55 0,000 0,15345033 0,16350819 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,15345033 0,16343581 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,15345033 0,16336349 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,15345033 0,16329124 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,15345033 0,16321905 ! aging GO:0007568 103 55 0,000 0,15345033 0,16314693 ! gastrulation GO:0007369 112 55 0,000 0,15345033 0,16307487 ! heart morphogenesis GO:0003007 97 55 0,000 0,15345033 0,16300287 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,15345033 0,16293093 ! RNA elongation GO:0006354 79 55 0,000 0,15345033 0,16285906 ! nuclear export GO:0051168 97 55 0,000 0,15345033 0,16278726 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,15345033 0,16271551 ! regulation of actin filament length GO:0030832 105 56 0,000 0,1560129 0,16535993 ! sensory perception of smell GO:0007608 80 56 0,000 0,1560129 0,16528712 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,1560129 0,16521437 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,1560129 0,16514168 ! proton transport GO:0015992 94 56 0,000 0,1560129 0,16506906 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,1585678 0,16769852 ! hydrogen transport GO:0006818 97 58 0,000 0,16111505 0,17031758 ! regulation of endocytosis GO:0030100 91 58 0,000 0,16111505 0,17024278 ! adult behavior GO:0030534 99 58 0,000 0,16111505 0,17016805 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,16111505 0,17009338 ! regulation of cellular component size GO:0032535 109 59 0,000 0,16365468 0,17269875 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,16365468 0,17262304 GO:0032313|regulation of Rab GTPase activity, ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,16618669 0,175217 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,16618669 0,17514025 ! regulation of heart contraction GO:0008016 110 60 0,000 0,16618669 0,17506357 ! camera-type eye development GO:0043010 116 60 0,000 0,16618669 0,17498695 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,16618669 0,17491041 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,16871113 0,17748972 ! mesoderm development GO:0007498 119 61 0,000 0,16871113 0,17741214 ! tRNA processing GO:0008033 89 61 0,000 0,16871113 0,17733464 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,16871113 0,1772572 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,17122801 0,17982304 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,17373735 0,18237874 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,17373735 0,1822992 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,17623918 0,18484371 ! cell redox homeostasis GO:0045454 102 64 0,000 0,17623918 0,18476316 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,17623918 0,18468269 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,17623918 0,18460229 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,17623918 0,18452196 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,17873351 0,18705212 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,17873351 0,1869708 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,17873351 0,18688954 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,18122038 0,18940757 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,18122038 0,18932533 ! extracellular matrix organization GO:0030198 133 66 0,000 0,18122038 0,18924315 ! secondary metabolic process GO:0019748 116 66 0,000 0,18122038 0,18916105 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,18369979 0,19166596 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,18369979 0,19158288 ! activation of MAPK activity GO:0000187 115 67 0,000 0,18369979 0,19149987 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,18369979 0,19141693 ! hexose catabolic process GO:0019320 104 67 0,000 0,18369979 0,19133407 ! adaptive immune response GO:0002250 119 67 0,000 0,18369979 0,19125128 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,18369979 0,19116856 ! amino acid transport GO:0006865 125 68 0,000 0,18617178 0,19365729 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,18617178 0,1935736 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,18617178 0,19348998 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 0,000 0,18617178 0,19340644 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,18617178 0,19332297 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,18617178 0,19323956 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,18863637 0,19571328 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,18863637 0,19562893 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,18863637 0,19554464 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,18863637 0,19546043 ! antigen processing and presentation GO:0019882 104 69 0,000 0,18863637 0,19537628 ! appendage morphogenesis GO:0035107 135 70 0,000 0,19109358 0,19783612 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,19354342 0,20028622 ! appendage development GO:0048736 136 71 0,000 0,19354342 0,20020012 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 0,000 0,19354342 0,20011408 ! carbohydrate transport GO:0008643 110 72 0,000 0,19598593 0,20255247 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,19598593 0,2024655 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,19598593 0,2023786 ! regulation of blood pressure GO:0008217 125 73 0,000 0,19842112 0,20480532 ! axon guidance GO:0007411 139 73 0,000 0,19842112 0,2047175 ! fertilization GO:0009566 90 73 0,000 0,19842112 0,20462975 ! transition metal ion transport GO:0000041 126 74 0,000 0,20084901 0,20704487 ! neurotransmitter transport GO:0006836 123 74 0,000 0,20084901 0,2069562 ! exocytosis GO:0006887 133 74 0,000 0,20084901 0,2068676 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,20084901 0,20677908 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,20326963 0,20918167 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,20326963 0,20909223 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,20326963 0,20900288 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,20326963 0,2089136 ! rhythmic process GO:0048511 128 75 0,000 0,20326963 0,2088244 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,20326963 0,20873527 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,205683 0,21112342 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,205683 0,21103339 ! regulation of catabolic process GO:0009894 161 76 0,000 0,205683 0,21094344 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,20808914 0,21332019 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,20808914 0,21322933 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,20808914 0,21313856 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,21048807 0,21550396 ! protein oligomerization GO:0051259 139 78 0,000 0,21048807 0,2154123 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,21287982 0,21776736 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,21287982 0,21767482 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,21287982 0,21758235 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,21287982 0,21748995 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,21287982 0,21739764 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,21526439 0,21973956 ! response to metal ion GO:0010038 140 80 0,000 0,21526439 0,21964637 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,21526439 0,21955326 ! protein import into nucleus GO:0006606 158 80 0,000 0,21526439 0,21946023 ! inorganic anion transport GO:0015698 138 80 0,000 0,21526439 0,21936727 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,21764183 0,22169612 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,21764183 0,2216023 ! nuclear import GO:0051170 161 81 0,000 0,21764183 0,22150856 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,22001214 0,2238263 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,22001214 0,2237317 ! regulation of lyase activity GO:0051339 160 83 0,000 0,22237534 0,22603932 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,22473147 0,2283378 ! regulation of ligase activity GO:0051340 142 84 0,000 0,22473147 0,22824141 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,22473147 0,22814511 ! response to unfolded protein GO:0006986 131 85 0,000 0,22708053 0,23043263 ! nucleosome assembly GO:0006334 122 85 0,000 0,22708053 0,23033548 ! response to inorganic substance GO:0010035 153 86 0,000 0,22942256 0,23261301 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,22942256 0,23251502 ! tube morphogenesis GO:0035239 176 86 0,000 0,22942256 0,23241712 ! alcohol catabolic process GO:0046164 130 86 0,000 0,22942256 0,2323193 ! amine transport GO:0015837 155 86 0,000 0,22942256 0,23222157 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,23175756 0,23448641 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,23175756 0,23438785 ! protein localization in nucleus GO:0034504 176 87 0,000 0,23175756 0,23428937 ! cellular respiration GO:0045333 135 88 0,000 0,23408557 0,23654342 ! regulation of neurological system process GO:0031644 148 88 0,000 0,23408557 0,23644411 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,23408557 0,23634489 ! cellular defense response GO:0006968 114 89 0,000 0,2364066 0,2385882 ! ossification GO:0001503 188 90 0,000 0,23872067 0,24082261 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,23872067 0,24072168 ! bone development GO:0060348 189 91 0,000 0,24102781 0,24294634 ! response to protein stimulus GO:0051789 149 91 0,000 0,24102781 0,2428446 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,24102781 0,24274295 ! nucleosome organization GO:0034728 138 92 0,000 0,24332803 0,24495701 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,24332803 0,24485456 ! vitamin metabolic process GO:0006766 139 92 0,000 0,24332803 0,24475219 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,24562136 0,2469557 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,24562136 0,24685254 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,24562136 0,24674947 ! regulation of membrane potential GO:0042391 164 93 0,000 0,24562136 0,24664649 ! female pregnancy GO:0007565 164 94 0,000 0,24790781 0,24883863 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,25246017 0,25330241 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,25246017 0,25319682 ! positive regulation of immune response GO:0050778 156 96 0,000 0,25246017 0,25309132 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,25472613 0,25525658 ! protein ubiquitination GO:0016567 217 97 0,000 0,25472613 0,25515032 ! hormone metabolic process GO:0042445 157 97 0,000 0,25472613 0,25504414 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,25698528 0,25719908 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,25698528 0,25709214 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,25923767 0,25923767