pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1064-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! myeloid leukocyte differentiation GO:0002573 46 25 4,000 6,584E-09 1,608E-05 ! regulation of DNA metabolic process GO:0051052 188 97 6,000 8,844E-09 1,08E-05 ! establishment of organelle localization GO:0051656 122 59 5,000 1,33E-08 1,083E-05 ! organelle localization GO:0051640 155 74 5,000 5,292E-08 3,232E-05 ! regulation of survival gene product expression GO:0045884 38 17 3,000 1,157E-07 5,655E-05 ! nuclear migration GO:0007097 13 6 2,000 3,796E-07 1,546E-04 ! establishment of spindle localization GO:0051293 16 6 2,000 3,796E-07 1,325E-04 GO:0051653|spindle localization, ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 3,796E-07 1,159E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of DNA replication GO:0006275 105 56 4,000 4,431E-07 1,203E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 1,059E-06 2,586E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 1,059E-06 2,351E-04 ! myeloid cell differentiation GO:0030099 126 67 4,000 1,094E-06 2,228E-04 ! macrophage differentiation GO:0030225 15 9 2,000 1,585E-06 2,979E-04 ! positive regulation of survival gene product expression GO:0045885 26 10 2,000 2,26E-06 3,943E-04 ! nucleus localization GO:0051647 22 11 2,000 3,101E-06 5,051E-04 ! regulation of cell projection assembly GO:0060491 33 12 2,000 4,127E-06 6,301E-04 ! establishment or maintenance of cell polarity GO:0007163 96 41 3,000 4,686E-06 6,734E-04 ! leukocyte differentiation GO:0002521 232 98 4,000 7,203E-06 9,776E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 7,203E-06 9,261E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 7,474E-06 9,129E-04 ! isoprenoid biosynthetic process GO:0008299 34 16 2,000 1,042E-05 1,212E-03 ! filopodium assembly GO:0046847 42 17 2,000 1,263E-05 1,403E-03 ! microspike assembly GO:0030035 46 18 2,000 1,513E-05 1,607E-03 ! cytokine-mediated signaling pathway GO:0019221 112 61 3,000 2,317E-05 2,359E-03 ! cholesterol biosynthetic process GO:0006695 39 22 2,000 2,833E-05 2,768E-03 ! positive regulation of B cell activation GO:0050871 42 22 2,000 2,833E-05 2,662E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 4,206E-05 3,805E-03 ! regulation of transcription factor activity GO:0051090 137 75 3,000 5,243E-05 4,574E-03 GO:0090046|regulation of transcription regulator activity, ! positive regulation of cell projection organization GO:0031346 66 27 2,000 5,328E-05 4,488E-03 ! regulation of chromosome organization GO:0033044 49 27 2,000 5,328E-05 4,338E-03 ! regulation of collagen biosynthetic process GO:0032965 7 5 1,000 7,181E-05 5,659E-03 ! lipoprotein particle clearance GO:0034381 10 5 1,000 7,181E-05 5,482E-03 ! response to protozoan GO:0001562 13 5 1,000 7,181E-05 5,316E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 7,181E-05 5,16E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 7,181E-05 5,012E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 7,181E-05 4,873E-03 ! lipoprotein catabolic process GO:0042159 11 5 1,000 7,181E-05 4,741E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 7,181E-05 4,617E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 7,181E-05 4,498E-03 ! metaphase GO:0051323 11 5 1,000 7,181E-05 4,386E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 7,352E-05 4,381E-03 ! sterol biosynthetic process GO:0016126 56 30 2,000 7,352E-05 4,276E-03 ! regulation of B cell activation GO:0050864 55 30 2,000 7,352E-05 4,177E-03 ! cholesterol metabolic process GO:0008203 148 85 3,000 8,556E-05 4,75E-03 ! spindle organization GO:0007051 50 32 2,000 8,946E-05 4,857E-03 ! regulation of DNA binding GO:0051101 167 89 3,000 1,023E-04 5,434E-03 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 1,075E-04 5,589E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 1,000 1,075E-04 5,472E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 1,075E-04 5,361E-03 ! regulation of collagen metabolic process GO:0010712 10 6 1,000 1,075E-04 5,254E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 1,075E-04 5,151E-03 GO:0045686|negative regulation of glial cell differentiation, ! neutrophil homeostasis GO:0001780 11 6 1,000 1,075E-04 5,052E-03 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 1,075E-04 4,956E-03 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 1,000 1,075E-04 4,864E-03 ! organ or tissue specific immune response GO:0002251 8 6 1,000 1,075E-04 4,776E-03 ! sterol metabolic process GO:0016125 166 94 3,000 1,265E-04 5,518E-03 ! mitotic sister chromatid segregation GO:0000070 63 36 2,000 1,278E-04 5,476E-03 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 2,000 1,278E-04 5,382E-03 ! sister chromatid segregation GO:0000819 65 37 2,000 1,388E-04 5,746E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,503E-04 6,118E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,503E-04 6,018E-03 ! neuron remodeling GO:0016322 16 7 1,000 1,503E-04 5,921E-03 ! monocyte differentiation GO:0030224 16 7 1,000 1,503E-04 5,827E-03 ! coenzyme A metabolic process GO:0015936 12 7 1,000 1,503E-04 5,736E-03 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 1,000 1,503E-04 5,648E-03 ! defense response to Gram-negative bacterium GO:0050829 10 7 1,000 1,503E-04 5,562E-03 ! meiosis I GO:0007127 74 38 2,000 1,504E-04 5,483E-03 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 2,000 1,504E-04 5,403E-03 ! isoprenoid metabolic process GO:0006720 70 39 2,000 1,626E-04 5,757E-03 ! positive regulation of leukocyte proliferation GO:0070665 70 39 2,000 1,626E-04 5,675E-03 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 2E-04 6,882E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 2E-04 6,786E-03 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 1,000 2E-04 6,693E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 2E-04 6,603E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 1,000 2E-04 6,515E-03 GO:0002688|regulation of leukocyte chemotaxis, ! myeloid cell homeostasis GO:0002262 15 8 1,000 2E-04 6,429E-03 ! negative regulation of DNA replication initiation GO:0032297 10 8 1,000 2E-04 6,346E-03 GO:0000076|DNA replication checkpoint, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 2,000 2,03E-04 6,36E-03 ! cytokinesis GO:0000910 84 42 2,000 2,03E-04 6,279E-03 ! positive regulation of transcription factor activity GO:0051091 71 43 2,000 2,179E-04 6,653E-03 GO:0090047|positive regulation of transcription regulator activity, ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 2,495E-04 7,525E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 1,000 2,567E-04 7,648E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 2,567E-04 7,555E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 2,567E-04 7,466E-03 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 2,567E-04 7,378E-03 ! regulation of telomere maintenance GO:0032204 17 9 1,000 2,567E-04 7,292E-03 ! leukocyte migration GO:0050900 75 46 2,000 2,664E-04 7,481E-03 ! pigmentation GO:0043473 103 46 2,000 2,664E-04 7,396E-03 ! regulation of JAK-STAT cascade GO:0046425 76 48 2,000 3,023E-04 8,299E-03 ! cellular component disassembly GO:0022411 89 48 2,000 3,023E-04 8,207E-03 ! positive regulation of DNA binding GO:0043388 83 48 2,000 3,023E-04 8,117E-03 ! regulation of inflammatory response GO:0050727 84 48 2,000 3,023E-04 8,029E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 3,203E-04 8,414E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 3,203E-04 8,324E-03 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 1,000 3,203E-04 8,237E-03 GO:0007520|myoblast fusion, ! COPI coating of Golgi vesicle GO:0048205 23 10 1,000 3,203E-04 8,151E-03 GO:0048200|Golgi transport vesicle coating, ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 3,203E-04 8,067E-03 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 3,203E-04 7,985E-03 ! polyamine biosynthetic process GO:0006596 13 10 1,000 3,203E-04 7,904E-03 ! intestinal cholesterol absorption GO:0030299 19 10 1,000 3,203E-04 7,825E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 3,203E-04 7,748E-03 GO:0045685|regulation of glial cell differentiation, ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 3,203E-04 7,672E-03 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 3,203E-04 7,597E-03 ! salivary gland development GO:0007431 28 10 1,000 3,203E-04 7,524E-03 ! positive regulation of acute inflammatory response GO:0002675 18 10 1,000 3,203E-04 7,452E-03 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 3,214E-04 7,408E-03 ! regulation of gene expression, epigenetic GO:0040029 116 50 2,000 3,413E-04 7,792E-03 ! regulation of cell projection organization GO:0031344 135 51 2,000 3,619E-04 8,187E-03 ! positive regulation of binding GO:0051099 88 52 2,000 3,833E-04 8,591E-03 ! Golgi vesicle budding GO:0048194 26 11 1,000 3,908E-04 8,679E-03 ! detection of mechanical stimulus GO:0050982 22 11 1,000 3,908E-04 8,601E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 3,908E-04 8,524E-03 ! syncytium formation GO:0006949 20 11 1,000 3,908E-04 8,449E-03 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 3,908E-04 8,375E-03 ! DNA methylation GO:0006306 19 11 1,000 3,908E-04 8,302E-03 GO:0006305|DNA alkylation, ! neuroblast proliferation GO:0007405 25 11 1,000 3,908E-04 8,23E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 3,908E-04 8,16E-03 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 1,000 3,908E-04 8,091E-03 ! germ cell migration GO:0008354 26 11 1,000 3,908E-04 8,023E-03 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 2,000 4,055E-04 8,256E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 4,055E-04 8,188E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! covalent chromatin modification GO:0016569 115 54 2,000 4,285E-04 8,581E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 4,681E-04 9,298E-03 ! hippocampus development GO:0021766 29 12 1,000 4,681E-04 9,223E-03 ! polyamine metabolic process GO:0006595 18 12 1,000 4,681E-04 9,149E-03 ! lipid digestion GO:0044241 21 12 1,000 4,681E-04 9,076E-03 ! entry into host cell GO:0030260 34 12 1,000 4,681E-04 9,005E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 4,681E-04 8,935E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 4,681E-04 8,865E-03 ! regulation of leukocyte migration GO:0002685 29 12 1,000 4,681E-04 8,797E-03 ! defense response to Gram-positive bacterium GO:0050830 14 12 1,000 4,681E-04 8,73E-03 ! establishment of cell polarity GO:0030010 21 12 1,000 4,681E-04 8,664E-03 ! regulation of chemokine production GO:0032642 18 13 1,000 5,523E-04 0,01014422 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 1,000 5,523E-04 0,01006852 ! endocrine pancreas development GO:0031018 25 13 1,000 5,523E-04 9,994E-03 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 5,523E-04 9,92E-03 ! exocrine system development GO:0035272 34 13 1,000 5,523E-04 9,848E-03 ! membrane protein proteolysis GO:0033619 33 13 1,000 5,523E-04 9,777E-03 GO:0006509|membrane protein ectodomain proteolysis, ! chromatin silencing GO:0006342 29 13 1,000 5,523E-04 9,706E-03 ! gland morphogenesis GO:0022612 31 13 1,000 5,523E-04 9,637E-03 ! regulation of acute inflammatory response GO:0002673 24 13 1,000 5,523E-04 9,569E-03 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 1,000 5,523E-04 9,501E-03 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 5,523E-04 9,435E-03 ! myotube differentiation GO:0014902 26 14 1,000 6,432E-04 0,01091164 ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 1,000 6,432E-04 0,01083639 ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 6,432E-04 0,01076216 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 1,000 6,432E-04 0,01068895 ! regulation of T-helper 2 type immune response GO:0002828 25 14 1,000 6,432E-04 0,01061673 ! regulation of RNA stability GO:0043487 33 14 1,000 6,432E-04 0,01054548 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 6,432E-04 0,01047517 ! regulation of protein complex assembly GO:0043254 132 63 2,000 6,741E-04 0,01090674 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 7,059E-04 0,01134569 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 7,408E-04 0,0118289 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 1,000 7,408E-04 0,01175209 ! vesicle coating GO:0006901 38 15 1,000 7,408E-04 0,01167627 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 7,408E-04 0,01160142 ! intestinal absorption GO:0050892 31 15 1,000 7,408E-04 0,01152753 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 7,723E-04 0,0119412 ! chromosome segregation GO:0007059 127 67 2,000 8,069E-04 0,01239811 ! cell projection assembly GO:0030031 138 68 2,000 8,425E-04 0,01286415 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 8,452E-04 0,01282441 ! DNA replication initiation GO:0006270 28 16 1,000 8,452E-04 0,01274525 ! negative regulation of inflammatory response GO:0050728 24 16 1,000 8,452E-04 0,01266706 ! regulation of T-helper cell differentiation GO:0045622 30 16 1,000 8,452E-04 0,01258982 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 8,791E-04 0,01301593 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 8,791E-04 0,01293752 ! negative regulation of kinase activity GO:0033673 145 70 2,000 9,167E-04 0,0134097 ! negative regulation of hormone secretion GO:0046888 26 17 1,000 9,562E-04 0,01390425 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 9,562E-04 0,01382197 ! endothelial cell migration GO:0043542 31 17 1,000 9,562E-04 0,01374067 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 1,000 9,562E-04 0,01366031 ! membrane budding GO:0006900 42 17 1,000 9,562E-04 0,01358089 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 1,000 9,562E-04 0,01350239 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 9,562E-04 0,01342479 ! positive regulation of anti-apoptosis GO:0045768 47 18 1,000 1,074E-03 0,01499019 ! limbic system development GO:0021761 40 18 1,000 1,074E-03 0,01490502 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 1,000 1,074E-03 0,01482081 ! regulation of immunoglobulin production GO:0002637 49 18 1,000 1,074E-03 0,01473755 ! defense response to virus GO:0051607 43 18 1,000 1,074E-03 0,01465521 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 1,077E-03 0,01461866 ! negative regulation of transferase activity GO:0051348 155 74 2,000 1,077E-03 0,01453789 ! positive regulation of translation GO:0045727 31 19 1,000 1,198E-03 0,01608105 ! negative regulation of defense response GO:0031348 27 19 1,000 1,198E-03 0,01599318 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 1,198E-03 0,01590626 ! neuron maturation GO:0042551 46 19 1,000 1,198E-03 0,01582028 ! mitotic chromosome condensation GO:0007076 37 19 1,000 1,198E-03 0,01573523 ! pigmentation during development GO:0048066 42 19 1,000 1,198E-03 0,01565108 ! peptide cross-linking GO:0018149 39 19 1,000 1,198E-03 0,01556783 ! visual learning GO:0008542 38 19 1,000 1,198E-03 0,01548546 ! peptide hormone secretion GO:0030072 32 19 1,000 1,198E-03 0,01540396 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 1,254E-03 0,01604255 ! steroid biosynthetic process GO:0006694 146 79 2,000 1,301E-03 0,01655667 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,329E-03 0,01681986 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 1,000 1,329E-03 0,01673316 ! protein amino acid acetylation GO:0006473 41 20 1,000 1,329E-03 0,01664735 ! response to alkaloid GO:0043279 38 20 1,000 1,329E-03 0,01656241 ! pancreas development GO:0031016 40 20 1,000 1,329E-03 0,01647834 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 1,329E-03 0,01639511 ! peptide secretion GO:0002790 38 20 1,000 1,329E-03 0,01631273 ! meiosis GO:0007126 143 81 2,000 1,398E-03 0,01708214 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 2,000 1,398E-03 0,01699715 ! meiotic cell cycle GO:0051321 144 82 2,000 1,449E-03 0,01752112 ! hormone secretion GO:0046879 39 21 1,000 1,466E-03 0,01764354 ! lipid phosphorylation GO:0046834 43 21 1,000 1,466E-03 0,01755705 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 1,466E-03 0,0174714 ! plasma membrane fusion GO:0045026 33 21 1,000 1,466E-03 0,01738659 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 1,466E-03 0,0173026 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 1,466E-03 0,01721941 ! positive regulation of inflammatory response GO:0050729 41 21 1,000 1,466E-03 0,01713702 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 1,466E-03 0,01705542 ! actin filament-based movement GO:0030048 47 21 1,000 1,466E-03 0,01697459 ! response to drug GO:0042493 149 83 2,000 1,5E-03 0,01728701 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 1,5E-03 0,01720585 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of transport GO:0051051 164 85 2,000 1,606E-03 0,01833793 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 1,000 1,61E-03 0,01829247 ! apoptotic nuclear changes GO:0030262 34 22 1,000 1,61E-03 0,01820778 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 1,000 1,61E-03 0,01812388 ! positive regulation of locomotion GO:0040017 44 22 1,000 1,61E-03 0,01804074 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 1,000 1,61E-03 0,01795836 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 1,61E-03 0,01787673 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 1,61E-03 0,01779584 ! positive regulation of cell activation GO:0050867 161 86 2,000 1,661E-03 0,01828042 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 2,000 1,717E-03 0,01881174 GO:0070201|regulation of establishment of protein localization, ! positive regulation of DNA replication GO:0045740 44 23 1,000 1,76E-03 0,01919588 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 1,76E-03 0,01911057 ! regulation of anti-apoptosis GO:0045767 62 23 1,000 1,76E-03 0,01902601 ! regulation of chemotaxis GO:0050920 45 23 1,000 1,76E-03 0,01894219 ! visual behavior GO:0007632 46 23 1,000 1,76E-03 0,01885911 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 1,76E-03 0,01877676 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 1,76E-03 0,01869512 ! vesicle targeting GO:0006903 49 23 1,000 1,76E-03 0,01861419 ! regulation of interleukin-6 production GO:0032675 31 23 1,000 1,76E-03 0,01853395 ! DNA modification GO:0006304 36 23 1,000 1,76E-03 0,01845441 ! hormone transport GO:0009914 41 23 1,000 1,76E-03 0,01837554 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 1,76E-03 0,01829735 ! positive regulation of protein modification process GO:0031401 156 90 2,000 1,892E-03 0,01958688 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 1,917E-03 0,01975755 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 1,917E-03 0,01967454 ! protein amino acid O-linked glycosylation GO:0006493 45 24 1,000 1,917E-03 0,01959222 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 1,917E-03 0,01951058 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 1,917E-03 0,01942962 ! purine ribonucleoside metabolic process GO:0046128 38 24 1,000 1,917E-03 0,01934934 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 1,000 1,917E-03 0,01926971 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,917E-03 0,01919074 ! pallium development GO:0021543 56 24 1,000 1,917E-03 0,01911241 ! platelet activation GO:0030168 41 24 1,000 1,917E-03 0,01903471 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 2,08E-03 0,02056997 ! negative regulation of DNA replication GO:0008156 45 25 1,000 2,08E-03 0,02048703 ! chromosome condensation GO:0030261 48 25 1,000 2,08E-03 0,02040475 ! regulation of behavior GO:0050795 48 25 1,000 2,08E-03 0,02032313 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 2,08E-03 0,02024216 ! interaction with host GO:0051701 66 25 1,000 2,08E-03 0,02016184 ! lymphocyte proliferation GO:0046651 55 25 1,000 2,08E-03 0,02008214 ! positive regulation of protein secretion GO:0050714 41 25 1,000 2,08E-03 0,02000308 ! leukocyte homeostasis GO:0001776 50 25 1,000 2,08E-03 0,01992464 ! regulation of defense response GO:0031347 171 95 2,000 2,208E-03 0,02106848 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 2,249E-03 0,02137946 ! initiation of viral infection GO:0019059 60 26 1,000 2,249E-03 0,02129659 ! macromolecular complex disassembly GO:0032984 54 26 1,000 2,249E-03 0,02121437 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 2,249E-03 0,02113277 ! digestive system process GO:0022600 49 26 1,000 2,249E-03 0,0210518 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 2,249E-03 0,02097145 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 2,249E-03 0,02089171 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of cell development GO:0010721 83 26 1,000 2,249E-03 0,02081258 GO:0050768|negative regulation of neurogenesis, ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 2,249E-03 0,02073404 ! positive regulation of nuclear division GO:0051785 41 26 1,000 2,249E-03 0,02065609 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 2,249E-03 0,02057873 ! regulation of protein localization GO:0032880 188 97 2,000 2,343E-03 0,02135413 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 2,425E-03 0,02202108 ! cellular response to oxidative stress GO:0034599 43 27 1,000 2,425E-03 0,02193952 ! leukocyte proliferation GO:0070661 59 27 1,000 2,425E-03 0,02185856 GO:0032943|mononuclear cell proliferation, ! skeletal muscle tissue development GO:0007519 223 100 2,000 2,554E-03 0,02294089 GO:0060538|skeletal muscle organ development, ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 2,607E-03 0,02332654 ! protein amino acid acylation GO:0043543 59 28 1,000 2,607E-03 0,02324141 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 2,607E-03 0,02315689 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 2,607E-03 0,02307299 ! group transfer coenzyme metabolic process GO:0006752 53 28 1,000 2,607E-03 0,0229897 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 2,795E-03 0,02456066 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 2,795E-03 0,02447263 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 2,795E-03 0,02438523 ! somitogenesis GO:0001756 52 29 1,000 2,795E-03 0,02429845 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 2,795E-03 0,02421228 ! acute-phase response GO:0006953 50 30 1,000 2,989E-03 0,02580473 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 2,989E-03 0,02571387 GO:0043433|negative regulation of transcription factor activity, ! peptide transport GO:0015833 60 31 1,000 3,19E-03 0,02734277 ! iron ion homeostasis GO:0055072 60 31 1,000 3,19E-03 0,02724717 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 3,19E-03 0,02715223 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 1,000 3,396E-03 0,02881122 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 3,396E-03 0,02871153 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 3,396E-03 0,02861253 ! response to mechanical stimulus GO:0009612 60 32 1,000 3,396E-03 0,0285142 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 3,396E-03 0,02841655 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 3,396E-03 0,02831956 ! myeloid leukocyte activation GO:0002274 53 32 1,000 3,396E-03 0,02822324 ! gene silencing GO:0016458 71 32 1,000 3,396E-03 0,02812757 ! negative regulation of response to external stimulus GO:0032102 50 33 1,000 3,609E-03 0,0297888 ! cholesterol homeostasis GO:0042632 60 33 1,000 3,609E-03 0,0296885 GO:0055092|sterol homeostasis, ! leukocyte chemotaxis GO:0030595 55 33 1,000 3,609E-03 0,02958887 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 74 33 1,000 3,609E-03 0,02948991 ! establishment of vesicle localization GO:0051650 67 33 1,000 3,609E-03 0,02939161 ! cholesterol transport GO:0030301 62 34 1,000 3,828E-03 0,0310703 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 3,828E-03 0,03096742 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 3,828E-03 0,03086522 ! negative regulation of secretion GO:0051048 68 35 1,000 4,053E-03 0,03257099 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 4,053E-03 0,0324642 ! telencephalon development GO:0021537 81 35 1,000 4,053E-03 0,03235811 ! sterol transport GO:0015918 63 35 1,000 4,053E-03 0,03225271 ! biogenic amine biosynthetic process GO:0042401 65 35 1,000 4,053E-03 0,03214799 ! vesicle localization GO:0051648 70 35 1,000 4,053E-03 0,03204396 ! negative regulation of DNA binding GO:0043392 67 36 1,000 4,284E-03 0,03376021 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 4,521E-03 0,03551232 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 4,521E-03 0,03539849 ! maintenance of protein location in cell GO:0032507 89 37 1,000 4,521E-03 0,0352854 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 4,521E-03 0,03517303 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 4,764E-03 0,03694443 ! DNA integrity checkpoint GO:0031570 82 38 1,000 4,764E-03 0,03682751 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 4,764E-03 0,03671134 ! negative regulation of binding GO:0051100 71 39 1,000 5,012E-03 0,03850653 ! learning GO:0007612 82 40 1,000 5,267E-03 0,04033541 ! nucleus organization GO:0006997 73 40 1,000 5,267E-03 0,04020937 ! lipid homeostasis GO:0055088 75 40 1,000 5,267E-03 0,0400841 ! Rho protein signal transduction GO:0007266 88 40 1,000 5,267E-03 0,03995962 ! regulation of hormone secretion GO:0046883 69 41 1,000 5,527E-03 0,0418055 ! maintenance of protein location GO:0045185 95 41 1,000 5,527E-03 0,04167647 ! ear morphogenesis GO:0042471 64 42 1,000 5,794E-03 0,04354933 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 5,794E-03 0,04341574 ! ribonucleoside metabolic process GO:0009119 64 42 1,000 5,794E-03 0,04328297 ! regulation of T cell differentiation GO:0045580 78 42 1,000 5,794E-03 0,04315101 ! regulation of protein secretion GO:0050708 77 42 1,000 5,794E-03 0,04301985 ! epithelial cell differentiation GO:0030855 83 43 1,000 6,065E-03 0,04490299 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 6,065E-03 0,04476733 ! regulation of T cell proliferation GO:0042129 80 43 1,000 6,065E-03 0,04463249 ! segmentation GO:0035282 78 43 1,000 6,065E-03 0,04449846 ! response to reactive oxygen species GO:0000302 75 44 1,000 6,343E-03 0,04639659 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 6,343E-03 0,04625809 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 6,627E-03 0,04818118 ! keratinocyte differentiation GO:0030216 81 45 1,000 6,627E-03 0,04803821 ! biopolymer methylation GO:0043414 91 45 1,000 6,627E-03 0,04789608 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 6,627E-03 0,04775479 ! maintenance of location in cell GO:0051651 101 45 1,000 6,627E-03 0,04761434 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 6,916E-03 0,0495459 ! positive regulation of protein transport GO:0051222 80 46 1,000 6,916E-03 0,04940103 ! response to insulin stimulus GO:0032868 98 47 1,000 7,21E-03 0,0513563 ! positive regulation of cell cycle GO:0045787 96 48 1,000 7,511E-03 0,05334004 ! positive regulation of defense response GO:0031349 88 48 1,000 7,511E-03 0,05318543 ! regulation of adaptive immune response GO:0002819 92 48 1,000 7,511E-03 0,05303172 ! methylation GO:0032259 97 48 1,000 7,511E-03 0,05287889 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 7,817E-03 0,05487461 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 7,817E-03 0,05471738 ! endocrine system development GO:0035270 109 50 1,000 8,128E-03 0,05673516 ! activation of caspase activity GO:0006919 95 50 1,000 8,128E-03 0,05657352 ! regulation of ossification GO:0030278 123 50 1,000 8,128E-03 0,0564128 ! epidermal cell differentiation GO:0009913 87 50 1,000 8,128E-03 0,05625299 ! positive regulation of cytokine production GO:0001819 94 50 1,000 8,128E-03 0,05609409 ! viral infectious cycle GO:0019058 104 51 1,000 8,445E-03 0,05811753 ! detection of abiotic stimulus GO:0009582 80 51 1,000 8,445E-03 0,05795427 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 8,768E-03 0,05999869 ! histone modification GO:0016570 104 52 1,000 8,768E-03 0,0598311 ! chromatin remodeling GO:0006338 122 53 1,000 9,096E-03 0,061896 ! vesicle organization GO:0016050 127 53 1,000 9,096E-03 0,06172407 ! regulation of angiogenesis GO:0045765 125 54 1,000 9,429E-03 0,06380897 ! membrane fusion GO:0006944 122 54 1,000 9,429E-03 0,0636327 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 9,429E-03 0,06345741 ! regulation of cell shape GO:0008360 142 54 1,000 9,429E-03 0,06328307 ! cell maturation GO:0048469 107 55 1,000 9,768E-03 0,06537693 ! response to UV GO:0009411 120 55 1,000 9,768E-03 0,06519831 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,01011184 0,06731122 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 0,01046126 0,06944801 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,01046126 0,06925981 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,01046126 0,06907262 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 1,000 0,01046126 0,06888644 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,01046126 0,06870126 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,01081599 0,07084038 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,01081599 0,07065097 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,01081599 0,07046257 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 1,000 0,01081599 0,07027517 ! maintenance of location GO:0051235 124 58 1,000 0,01081599 0,07008876 ! lipid modification GO:0030258 112 60 1,000 0,01154121 0,07459042 ! DNA catabolic process GO:0006308 94 60 1,000 0,01154121 0,07439361 ! kidney development GO:0001822 133 60 1,000 0,01154121 0,07419784 ! positive regulation of secretion GO:0051047 110 61 1,000 0,01191165 0,07637836 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 0,01191165 0,07617841 ! viral reproductive process GO:0022415 132 62 1,000 0,01228726 0,07837539 ! nucleoside metabolic process GO:0009116 91 62 1,000 0,01228726 0,07817129 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,01228726 0,07796824 ! regulation of mitosis GO:0007088 112 63 1,000 0,01266802 0,08017608 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,01266802 0,0799689 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,01305389 0,08219241 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01343239 0,08435817 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01343239 0,08414187 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01343239 0,08392667 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01343239 0,08371257 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01343239 0,08349956 ! neuron fate determination GO:0048664 7 5 0,000 0,01343239 0,08328764 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01343239 0,08307678 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01343239 0,08286699 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01343239 0,08265826 ! polyol transport GO:0015791 12 5 0,000 0,01343239 0,08245057 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01343239 0,08224393 ! response to superoxide GO:0000303 10 5 0,000 0,01343239 0,08203832 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01343239 0,08183374 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01343239 0,08163017 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01343239 0,08142761 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01343239 0,08122606 ! female meiosis GO:0007143 10 5 0,000 0,01343239 0,0810255 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01343239 0,08082593 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01343239 0,08062734 ! hypothalamus development GO:0021854 9 5 0,000 0,01343239 0,08042973 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01343239 0,08023308 ! cobalt ion transport GO:0006824 11 5 0,000 0,01343239 0,08003739 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01343239 0,07984265 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01343239 0,07964886 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01343239 0,079456 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01343239 0,07926408 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01343239 0,07907308 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01343239 0,078883 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01343239 0,07869383 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01343239 0,07850557 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! transposition GO:0032196 9 5 0,000 0,01343239 0,07831821 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01343239 0,07813174 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01343239 0,07794615 ! negative chemotaxis GO:0050919 16 5 0,000 0,01343239 0,07776144 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01343239 0,07757761 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01343239 0,07739464 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01343239 0,07721254 ! behavioral response to pain GO:0048266 10 5 0,000 0,01343239 0,07703129 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01343239 0,07685089 ! Notch receptor processing GO:0007220 11 5 0,000 0,01343239 0,07667133 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01343239 0,07649261 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01343239 0,07631472 ! micturition GO:0060073 9 5 0,000 0,01343239 0,07613765 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01343239 0,07596141 ! copulation GO:0007620 9 5 0,000 0,01343239 0,07578598 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01343239 0,07561136 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01343239 0,07543754 ! bioluminescence GO:0008218 9 5 0,000 0,01343239 0,07526452 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01343239 0,07509229 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01343239 0,07492084 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01343239 0,07475018 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01343239 0,07458029 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01343239 0,07441118 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01343239 0,07424283 ! grooming behavior GO:0007625 6 5 0,000 0,01343239 0,07407523 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01343239 0,0739084 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01343239 0,07374231 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01343239 0,07357697 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01343239 0,07341237 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01343239 0,0732485 ! lymph vessel development GO:0001945 10 5 0,000 0,01343239 0,07308536 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01343239 0,07292295 ! endochondral ossification GO:0001958 17 5 0,000 0,01343239 0,07276126 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01343239 0,07260029 ! single strand break repair GO:0000012 8 5 0,000 0,01343239 0,07244002 ! parathyroid gland development GO:0060017 14 5 0,000 0,01343239 0,07228046 ! anagen GO:0042640 7 5 0,000 0,01343239 0,0721216 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01343239 0,07196344 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01343239 0,07180597 ! cytokine secretion GO:0050663 15 5 0,000 0,01343239 0,07164919 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01343239 0,07149309 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01343239 0,07133767 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01343239 0,07118293 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01343239 0,07102885 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01343239 0,07087544 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01343239 0,07072269 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01343239 0,0705706 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01343239 0,07041916 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01343239 0,07026837 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01343239 0,07011822 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01343239 0,06996872 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01343239 0,06981985 ! microvillus organization GO:0032528 8 5 0,000 0,01343239 0,06967161 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01343239 0,069524 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01343239 0,06937702 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01343239 0,06923065 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01343239 0,0690849 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01343239 0,06893977 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01343239 0,06879524 ! polyol catabolic process GO:0046174 9 5 0,000 0,01343239 0,06865132 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01343239 0,06850799 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01343239 0,06836527 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01343239 0,06822314 ! muscle cell migration GO:0014812 8 5 0,000 0,01343239 0,0680816 ! mitochondrial fission GO:0000266 8 5 0,000 0,01343239 0,06794064 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01343239 0,06780027 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01343239 0,06766047 ! mRNA transcription GO:0009299 10 5 0,000 0,01343239 0,06752125 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01343239 0,06738261 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01343239 0,06724453 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01343239 0,06710701 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01343239 0,06697006 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01343239 0,06683366 ! monocyte activation GO:0042117 10 5 0,000 0,01343239 0,06669782 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01343239 0,06656253 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01343239 0,06642779 ! response to food GO:0032094 6 5 0,000 0,01343239 0,06629359 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01343239 0,06615994 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01343239 0,06602682 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01343239 0,06589423 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01343239 0,06576218 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01343239 0,06563066 ! forebrain neuron development GO:0021884 13 5 0,000 0,01343239 0,06549966 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01343239 0,06536918 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01343239 0,06523922 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01343239 0,06510978 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01343239 0,06498085 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01343239 0,06485243 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01343239 0,06472451 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01343239 0,0645971 ! lipid glycosylation GO:0030259 7 5 0,000 0,01343239 0,06447019 ! nucleobase transport GO:0015851 6 5 0,000 0,01343239 0,06434378 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01343239 0,06421786 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01343239 0,06409244 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01343239 0,0639675 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01343239 0,06384305 ! basic amino acid transport GO:0015802 12 5 0,000 0,01343239 0,06371909 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01343239 0,0635956 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01343239 0,06347259 ! actin nucleation GO:0045010 11 5 0,000 0,01343239 0,06335006 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01343239 0,06322799 ! depurination GO:0045007 5 5 0,000 0,01343239 0,0631064 ! depyrimidination GO:0045008 10 5 0,000 0,01343239 0,06298528 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01343239 0,06286461 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01343239 0,06274441 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01343239 0,06262467 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01343239 0,06250539 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01343239 0,06238656 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01343239 0,06226818 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01343239 0,06215024 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01343239 0,06203276 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01343239 0,06191571 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01343239 0,06179911 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01343239 0,06168295 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01343239 0,06156722 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01343239 0,06145193 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01343239 0,06133706 ! response to arsenic GO:0046685 11 5 0,000 0,01343239 0,06122263 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01343239 0,06110862 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01343239 0,06099504 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01343239 0,06088187 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01343239 0,06076913 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01343239 0,0606568 ! response to mercury ion GO:0046689 8 5 0,000 0,01343239 0,06054489 ! response to cadmium ion GO:0046686 7 5 0,000 0,01343239 0,06043339 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01343239 0,0603223 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01343239 0,06021161 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01343239 0,06010133 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01343239 0,05999146 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01343239 0,05988199 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01343239 0,05977291 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01343239 0,05966423 ! decidualization GO:0046697 11 5 0,000 0,01343239 0,05955595 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01343239 0,05944806 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01343239 0,05934056 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01343239 0,05923345 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01343239 0,05912672 ! embryonic cleavage GO:0040016 6 5 0,000 0,01343239 0,05902038 ! peroxisome fission GO:0016559 5 5 0,000 0,01343239 0,05891441 ! histone demethylation GO:0016577 13 5 0,000 0,01343239 0,05880883 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01343239 0,05870363 ! mitotic recombination GO:0006312 9 5 0,000 0,01343239 0,0585988 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01343239 0,05849435 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01343239 0,05839026 ! metaphase plate congression GO:0051310 7 5 0,000 0,01343239 0,05828655 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01343239 0,05818321 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01343239 0,05808023 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01343239 0,05797761 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01343239 0,05787536 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01343239 0,05777347 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01343239 0,05767193 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01343239 0,05757075 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01343239 0,05746993 ! B cell homeostasis GO:0001782 13 5 0,000 0,01343239 0,05736946 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01343239 0,05726933 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01343239 0,05716956 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01343239 0,05707014 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01343239 0,05697106 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01343239 0,05687232 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01343239 0,05677393 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01343239 0,05667587 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01343239 0,05657815 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01343239 0,05648077 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01343239 0,05638373 ! response to redox state GO:0051775 6 5 0,000 0,01343239 0,05628701 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01343239 0,05619063 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01343239 0,05609458 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01343239 0,05599885 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01343239 0,05590346 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01343239 0,05580838 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01343239 0,05571363 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01343239 0,0556192 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01343239 0,05552509 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01343239 0,0554313 ! striatum development GO:0021756 14 5 0,000 0,01343239 0,05533782 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01343239 0,05524466 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01343239 0,05515181 ! glial cell migration GO:0008347 10 5 0,000 0,01343239 0,05505928 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01343239 0,05496705 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01343239 0,05487513 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01343239 0,05478352 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01343239 0,05469221 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01343239 0,05460121 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01343239 0,05451051 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01343239 0,05442011 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01343239 0,05433001 ! neuroprotection GO:0043526 8 5 0,000 0,01343239 0,05424021 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01343239 0,05415071 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01343239 0,0540615 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01343239 0,05397258 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01343239 0,05388396 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01343239 0,05379562 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01343239 0,05370758 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01343239 0,05361982 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01343239 0,05353235 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01343239 0,05344516 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01343239 0,05335826 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01343239 0,05327164 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01343239 0,0531853 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01343239 0,05309924 ! spindle assembly GO:0051225 6 5 0,000 0,01343239 0,05301346 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01343239 0,05292795 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01343239 0,05284272 ! protein palmitoylation GO:0018345 12 5 0,000 0,01343239 0,05275776 ! drug metabolic process GO:0017144 7 5 0,000 0,01343239 0,05267308 ! stem cell division GO:0017145 11 5 0,000 0,01343239 0,05258867 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01343239 0,05250453 ! organ regeneration GO:0031100 7 5 0,000 0,01343239 0,05242065 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01343239 0,05233705 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01343239 0,05225371 ! positive regulation of cell motion GO:0051272 157 65 1,000 0,01344485 0,05221904 ! ear development GO:0043583 114 66 1,000 0,01384087 0,05367182 ! regulation of cytokine biosynthetic process GO:0042035 108 66 1,000 0,01384087 0,05358676 ! gonad development GO:0008406 115 66 1,000 0,01384087 0,05350197 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,01384087 0,05341745 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,01424191 0,05487854 ! detection of external stimulus GO:0009581 102 68 1,000 0,01464796 0,05635426 ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,01464796 0,05626566 ! viral reproduction GO:0016032 142 68 1,000 0,01464796 0,05617733 ! negative regulation of cell size GO:0045792 144 69 1,000 0,01505897 0,0576631 ! lung development GO:0030324 165 69 1,000 0,01505897 0,05757286 ! urogenital system development GO:0001655 149 69 1,000 0,01505897 0,0574829 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,01505897 0,05739323 ! developmental maturation GO:0021700 128 69 1,000 0,01505897 0,05730383 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,01589578 0,06039407 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,01589578 0,06030029 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01609736 0,06097032 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01609736 0,06087594 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01609736 0,06078185 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01609736 0,06068805 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01609736 0,06059454 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01609736 0,06050132 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01609736 0,06040839 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01609736 0,06031573 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01609736 0,06022337 ! response to oxygen radical GO:0000305 11 6 0,000 0,01609736 0,06013128 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01609736 0,06003948 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01609736 0,05994796 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01609736 0,05985671 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01609736 0,05976574 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01609736 0,05967505 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01609736 0,05958463 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01609736 0,05949449 ! forebrain regionalization GO:0021871 9 6 0,000 0,01609736 0,05940462 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01609736 0,05931502 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01609736 0,05922569 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01609736 0,05913663 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01609736 0,05904784 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01609736 0,05895931 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01609736 0,05887105 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01609736 0,05878305 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01609736 0,05869531 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01609736 0,05860784 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01609736 0,05852062 ! malate metabolic process GO:0006108 13 6 0,000 0,01609736 0,05843367 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01609736 0,05834697 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01609736 0,05826053 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01609736 0,05817435 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01609736 0,05808842 ! protein refolding GO:0042026 15 6 0,000 0,01609736 0,05800274 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01609736 0,05791732 ! opsonization GO:0008228 8 6 0,000 0,01609736 0,05783215 ! mating behavior GO:0007617 7 6 0,000 0,01609736 0,05774722 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01609736 0,05766255 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01609736 0,05757812 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01609736 0,05749395 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01609736 0,05741001 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01609736 0,05732632 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01609736 0,05724288 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01609736 0,05715968 ! toxin metabolic process GO:0009404 11 6 0,000 0,01609736 0,05707672 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01609736 0,056994 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01609736 0,05691152 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01609736 0,05682928 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01609736 0,05674727 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01609736 0,0566655 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01609736 0,05658397 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01609736 0,05650267 ! thymic T cell selection GO:0045061 16 6 0,000 0,01609736 0,05642161 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01609736 0,05634077 ! protein lipoylation GO:0009249 10 6 0,000 0,01609736 0,05626017 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01609736 0,0561798 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01609736 0,05609966 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01609736 0,05601974 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01609736 0,05594006 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01609736 0,0558606 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01609736 0,05578136 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01609736 0,05570235 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! response to pH GO:0009268 10 6 0,000 0,01609736 0,05562356 ! hyperosmotic response GO:0006972 10 6 0,000 0,01609736 0,055545 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01609736 0,05546666 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01609736 0,05538853 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01609736 0,05531063 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01609736 0,05523295 ! urea metabolic process GO:0019627 7 6 0,000 0,01609736 0,05515548 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01609736 0,05507823 ! neutrophil activation GO:0042119 7 6 0,000 0,01609736 0,0550012 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01609736 0,05492438 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01609736 0,05484778 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01609736 0,05477139 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01609736 0,05469521 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01609736 0,05461925 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01609736 0,05454349 ! neuron apoptosis GO:0051402 15 6 0,000 0,01609736 0,05446795 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01609736 0,05439261 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01609736 0,05431748 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01609736 0,05424256 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01609736 0,05416785 ! carnitine transport GO:0015879 10 6 0,000 0,01609736 0,05409334 GO:0015838|betaine transport, ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01609736 0,05401904 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01609736 0,05394494 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01609736 0,05387104 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01609736 0,05379734 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01609736 0,05372385 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01609736 0,05365056 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01609736 0,05357746 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01609736 0,05350457 ! neural nucleus development GO:0048857 19 6 0,000 0,01609736 0,05343187 ! response to UV-C GO:0010225 14 6 0,000 0,01609736 0,05335937 ! astrocyte development GO:0014002 16 6 0,000 0,01609736 0,05328707 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01609736 0,05321496 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01609736 0,05314305 ! interaction with symbiont GO:0051702 14 6 0,000 0,01609736 0,05307133 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01609736 0,05299981 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01609736 0,05292848 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01609736 0,05285734 ! response to copper ion GO:0046688 10 6 0,000 0,01609736 0,05278639 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01609736 0,05271563 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01609736 0,05264506 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01609736 0,05257468 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01609736 0,05250448 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01609736 0,05243448 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01609736 0,05236466 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01609736 0,05229503 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01609736 0,05222558 ! hair follicle maturation GO:0048820 8 6 0,000 0,01609736 0,05215631 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01609736 0,05208723 ! Schwann cell development GO:0014044 15 6 0,000 0,01609736 0,05201833 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01609736 0,05194962 ! response to pheromone GO:0019236 6 6 0,000 0,01609736 0,05188108 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01609736 0,05181273 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01609736 0,05174455 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01609736 0,05167656 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01609736 0,05160874 ! subpallium development GO:0021544 15 6 0,000 0,01609736 0,0515411 ! neural tube patterning GO:0021532 8 6 0,000 0,01609736 0,05147364 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01609736 0,05140635 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01609736 0,05133924 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01609736 0,05127231 ! G2 phase GO:0051319 16 6 0,000 0,01609736 0,05120555 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01609736 0,05113896 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01609736 0,05107254 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01609736 0,0510063 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01609736 0,05094023 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01609736 0,05087433 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01609736 0,0508086 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01609736 0,05074304 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01609736 0,05067765 ! receptor internalization GO:0031623 11 6 0,000 0,01609736 0,05061243 ! plasminogen activation GO:0031639 9 6 0,000 0,01609736 0,05054738 ! protein deubiquitination GO:0016579 16 6 0,000 0,01609736 0,05048249 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01609736 0,05041777 ! protein destabilization GO:0031648 9 6 0,000 0,01609736 0,05035321 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01609736 0,05028882 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01609736 0,0502246 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01609736 0,05016053 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01609736 0,05009664 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01609736 0,0500329 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01609736 0,04996933 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01609736 0,04990591 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01609736 0,04984266 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01609736 0,04977957 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01609736 0,04971664 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01609736 0,04965386 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01609736 0,04959125 ! neural plate development GO:0001840 9 6 0,000 0,01609736 0,04952879 ! catecholamine transport GO:0051937 9 6 0,000 0,01609736 0,04946649 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01609736 0,04940435 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01609736 0,04934236 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01609736 0,04928052 ! maternal placenta development GO:0001893 12 6 0,000 0,01609736 0,04921885 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01609736 0,04915732 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01609736 0,04909595 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01609736 0,04903474 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01609736 0,04897367 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01609736 0,04891276 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01609736 0,048852 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01609736 0,04879139 GO:0055081|anion homeostasis, ! respiratory tube development GO:0030323 171 72 1,000 0,01632152 0,0494095 ! actin filament organization GO:0007015 167 72 1,000 0,01632152 0,04934835 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,01632152 0,04928735 ! humoral immune response GO:0006959 115 73 1,000 0,01675211 0,0505252 ! regulation of immune effector process GO:0002697 156 73 1,000 0,01675211 0,0504629 ! acute inflammatory response GO:0002526 118 74 1,000 0,01718753 0,05171076 ! regulation of caspase activity GO:0043281 136 74 1,000 0,01718753 0,05164715 ! respiratory system development GO:0060541 175 74 1,000 0,01718753 0,0515837 ! reproductive structure development GO:0048608 131 75 1,000 0,01762774 0,05283996 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,01762774 0,05277521 ! eye development GO:0001654 155 75 1,000 0,01762774 0,05271061 ! learning or memory GO:0007611 161 76 1,000 0,01807272 0,05397513 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01852244 0,05525068 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,01852244 0,0551833 ! tRNA transcription GO:0009304 17 7 0,000 0,01875521 0,05580875 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01875521 0,05574086 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01875521 0,05567313 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01875521 0,05560556 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01875521 0,05553816 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01875521 0,05547093 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01875521 0,05540385 ! sleep GO:0030431 16 7 0,000 0,01875521 0,05533694 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01875521 0,05527019 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01875521 0,0552036 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01875521 0,05513717 ! prostate gland development GO:0030850 14 7 0,000 0,01875521 0,0550709 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01875521 0,05500478 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01875521 0,05493883 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01875521 0,05487304 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01875521 0,0548074 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01875521 0,05474192 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01875521 0,05467659 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01875521 0,05461142 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01875521 0,05454641 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01875521 0,05448155 ! glycolipid transport GO:0046836 11 7 0,000 0,01875521 0,05441685 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01875521 0,0543523 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01875521 0,0542879 ! neuron adhesion GO:0007158 14 7 0,000 0,01875521 0,05422365 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01875521 0,05415956 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01875521 0,05409561 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01875521 0,05403182 ! mRNA stabilization GO:0048255 18 7 0,000 0,01875521 0,05396818 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01875521 0,05390469 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01875521 0,05384135 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01875521 0,05377815 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01875521 0,05371511 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01875521 0,05365221 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01875521 0,05358946 ! lipoprotein transport GO:0042953 14 7 0,000 0,01875521 0,05352685 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01875521 0,05346439 ! rhythmic behavior GO:0007622 17 7 0,000 0,01875521 0,05340208 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01875521 0,05333991 GO:0042069|regulation of catecholamine metabolic process, ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01875521 0,05327789 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01875521 0,05321601 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01875521 0,05315428 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01875521 0,05309268 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01875521 0,05303123 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01875521 0,05296992 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01875521 0,05290876 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01875521 0,05284773 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01875521 0,05278685 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01875521 0,0527261 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01875521 0,0526655 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01875521 0,05260503 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01875521 0,05254471 ! spinal cord patterning GO:0021511 14 7 0,000 0,01875521 0,05248452 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01875521 0,05242447 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01875521 0,05236455 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01875521 0,05230478 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01875521 0,05224514 ! adrenal gland development GO:0030325 17 7 0,000 0,01875521 0,05218563 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01875521 0,05212626 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01875521 0,05206703 ! ovulation GO:0030728 10 7 0,000 0,01875521 0,05200793 ! adenohypophysis development GO:0021984 11 7 0,000 0,01875521 0,05194896 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01875521 0,05189013 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01875521 0,05183143 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01875521 0,05177286 ! microtubule nucleation GO:0007020 21 7 0,000 0,01875521 0,05171443 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01875521 0,05165613 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01875521 0,05159796 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01875521 0,05153992 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01875521 0,05148201 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01875521 0,05142423 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01875521 0,05136658 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01875521 0,05130905 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01875521 0,05125166 ! galactose metabolic process GO:0006012 13 7 0,000 0,01875521 0,0511944 ! vesicle fusion GO:0006906 20 7 0,000 0,01875521 0,05113726 ! response to dietary excess GO:0002021 8 7 0,000 0,01875521 0,05108025 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01875521 0,05102337 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01875521 0,05096661 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01875521 0,05090998 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01875521 0,05085348 ! organ growth GO:0035265 15 7 0,000 0,01875521 0,0507971 ! nucleoside transport GO:0015858 11 7 0,000 0,01875521 0,05074085 ! nucleoside salvage GO:0043174 11 7 0,000 0,01875521 0,05068472 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01875521 0,05062871 ! male sex determination GO:0030238 15 7 0,000 0,01875521 0,05057283 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01875521 0,05051707 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01875521 0,05046144 ! parturition GO:0007567 16 7 0,000 0,01875521 0,05040592 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01875521 0,05035053 ! rRNA modification GO:0000154 14 7 0,000 0,01875521 0,05029526 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01875521 0,05024012 ! spindle checkpoint GO:0031577 16 7 0,000 0,01875521 0,05018509 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01875521 0,05013018 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01875521 0,05007539 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01875521 0,05002073 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01875521 0,04996618 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01875521 0,04991175 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01875521 0,04985744 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01875521 0,04980324 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01875521 0,04974917 ! fibrinolysis GO:0042730 11 7 0,000 0,01875521 0,04969521 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01875521 0,04964137 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01875521 0,04958765 ! eating behavior GO:0042755 8 7 0,000 0,01875521 0,04953404 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01875521 0,04948055 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01875521 0,04942717 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01875521 0,04937391 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01875521 0,04932076 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01875521 0,04926773 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01875521 0,04921481 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01875521 0,049162 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01875521 0,04910931 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01875521 0,04905673 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01875521 0,04900426 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01875521 0,04895191 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01875521 0,04889966 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01875521 0,04884753 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01875521 0,04879551 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01875521 0,0487436 ! histone ubiquitination GO:0016574 9 7 0,000 0,01875521 0,0486918 ! regulation of meiosis GO:0040020 12 7 0,000 0,01875521 0,04864011 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01875521 0,04858853 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01875521 0,04853706 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01875521 0,0484857 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01875521 0,04843445 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01875521 0,0483833 ! transcription termination GO:0006353 14 7 0,000 0,01875521 0,04833226 ! anaphase GO:0051322 18 7 0,000 0,01875521 0,04828133 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01875521 0,04823051 ! axonal fasciculation GO:0007413 19 7 0,000 0,01875521 0,0481798 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01875521 0,04812919 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01875521 0,04807868 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01875521 0,04802829 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01875521 0,04797799 ! diuresis GO:0030146 12 7 0,000 0,01875521 0,04792781 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01875521 0,04787773 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01875521 0,04782775 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01875521 0,04777788 ! antibiotic transport GO:0042891 9 7 0,000 0,01875521 0,04772811 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01875521 0,04767844 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01875521 0,04762888 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01875521 0,04757942 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01875521 0,04753007 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01875521 0,04748081 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01875521 0,04743166 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01875521 0,04738261 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01875521 0,04733366 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01875521 0,04728481 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01875521 0,04723607 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01875521 0,04718742 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01875521 0,04713887 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01875521 0,04709043 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01875521 0,04704208 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01875521 0,04699383 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01875521 0,04694568 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01875521 0,04689763 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01875521 0,04684968 ! muscle adaptation GO:0043500 13 7 0,000 0,01875521 0,04680182 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01875521 0,04675407 ! retina homeostasis GO:0001895 12 7 0,000 0,01875521 0,04670641 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01875521 0,04665884 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01875521 0,04661138 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01875521 0,04656401 ! lipoprotein metabolic process GO:0042157 147 78 1,000 0,01897686 0,04706647 ! blood coagulation GO:0007596 151 79 1,000 0,01943597 0,04815626 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,01943597 0,04810747 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,01989973 0,04920551 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,01989973 0,04915575 ! muscle cell differentiation GO:0042692 178 81 1,000 0,02036812 0,05026193 ! response to hypoxia GO:0001666 178 81 1,000 0,02036812 0,05021121 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,0208411 0,05132541 ! response to oxygen levels GO:0070482 183 83 1,000 0,02131866 0,05244862 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02140596 0,05261042 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02140596 0,05255754 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,02140596 0,05250477 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02140596 0,05245211 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02140596 0,05239955 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02140596 0,0523471 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02140596 0,05229475 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02140596 0,05224251 ! male meiosis GO:0007140 9 8 0,000 0,02140596 0,05219037 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02140596 0,05213834 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02140596 0,05208641 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02140596 0,05203458 ! meiotic prophase I GO:0007128 14 8 0,000 0,02140596 0,05198286 ! response to zinc ion GO:0010043 12 8 0,000 0,02140596 0,05193123 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02140596 0,05187972 ! oligopeptide transport GO:0006857 16 8 0,000 0,02140596 0,0518283 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02140596 0,05177698 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02140596 0,05172577 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02140596 0,05167466 ! signal peptide processing GO:0006465 12 8 0,000 0,02140596 0,05162365 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02140596 0,05157274 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02140596 0,05152192 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02140596 0,05147121 ! succinate metabolic process GO:0006105 17 8 0,000 0,02140596 0,0514206 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02140596 0,05137009 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02140596 0,05131968 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02140596 0,05126937 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02140596 0,05121915 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02140596 0,05116903 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02140596 0,05111902 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02140596 0,0510691 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02140596 0,05101927 ! reflex GO:0060004 17 8 0,000 0,02140596 0,05096955 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02140596 0,05091992 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02140596 0,05087038 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02140596 0,05082095 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02140596 0,05077161 ! pigment granule organization GO:0048753 17 8 0,000 0,02140596 0,05072236 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02140596 0,05067321 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02140596 0,05062416 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02140596 0,0505752 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02140596 0,05052633 ! histidine catabolic process GO:0006548 10 8 0,000 0,02140596 0,05047756 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02140596 0,05042888 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02140596 0,0503803 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02140596 0,05033181 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,02140596 0,05028342 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02140596 0,05023511 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02140596 0,0501869 ! melanin metabolic process GO:0006582 17 8 0,000 0,02140596 0,05013879 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02140596 0,05009076 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02140596 0,05004283 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02140596 0,04999498 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02140596 0,04994723 ! macrophage activation GO:0042116 13 8 0,000 0,02140596 0,04989957 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02140596 0,04985201 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02140596 0,04980453 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02140596 0,04975714 ! purine salvage GO:0043101 12 8 0,000 0,02140596 0,04970984 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02140596 0,04966263 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02140596 0,04961552 ! osteoblast development GO:0002076 17 8 0,000 0,02140596 0,04956849 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02140596 0,04952155 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02140596 0,0494747 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02140596 0,04942793 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02140596 0,04938126 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02140596 0,04933467 ! response to UV-B GO:0010224 17 8 0,000 0,02140596 0,04928817 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02140596 0,04924176 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02140596 0,04919544 ! intermediate filament organization GO:0045109 12 8 0,000 0,02140596 0,0491492 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02140596 0,04910305 ! cellular extravasation GO:0045123 13 8 0,000 0,02140596 0,04905699 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02140596 0,04901102 ! response to antibiotic GO:0046677 11 8 0,000 0,02140596 0,04896512 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02140596 0,04891932 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02140596 0,0488736 ! DNA topological change GO:0006265 12 8 0,000 0,02140596 0,04882797 ! response to tropane GO:0014073 15 8 0,000 0,02140596 0,04878242 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02140596 0,04873696 ! melanosome transport GO:0032402 13 8 0,000 0,02140596 0,04869158 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02140596 0,04864628 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02140596 0,04860107 ! mast cell activation GO:0045576 14 8 0,000 0,02140596 0,04855595 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02140596 0,0485109 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02140596 0,04846594 ! gas homeostasis GO:0033483 14 8 0,000 0,02140596 0,04842107 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02140596 0,04837628 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02140596 0,04833157 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02140596 0,04828694 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02140596 0,04824239 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02140596 0,04819793 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02140596 0,04815355 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02140596 0,04810925 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02140596 0,04806503 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02140596 0,04802089 ! response to tumor cell GO:0002347 16 8 0,000 0,02140596 0,04797684 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02140596 0,04793286 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,02140596 0,04788897 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02140596 0,04784515 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02140596 0,04780142 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02140596 0,04775777 ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02140596 0,04771419 ! hormone catabolic process GO:0042447 17 8 0,000 0,02140596 0,0476707 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02140596 0,04762728 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02140596 0,04758394 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02140596 0,04754068 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02140596 0,04749751 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02140596 0,0474544 GO:0010828|positive regulation of glucose transport, ! adult feeding behavior GO:0008343 10 8 0,000 0,02140596 0,04741138 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02140596 0,04736844 ! ATP catabolic process GO:0006200 11 8 0,000 0,02140596 0,04732557 ! blastocyst growth GO:0001832 19 8 0,000 0,02140596 0,04728278 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02140596 0,04724007 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02140596 0,04719743 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02140596 0,04715487 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02140596 0,04711239 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02140596 0,04706999 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02140596 0,04702766 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02140596 0,0469854 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02140596 0,04694323 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02140596 0,04690112 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02140596 0,0468591 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02140596 0,04681715 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02140596 0,04677527 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02140596 0,04673347 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02140596 0,04669174 ! protein prenylation GO:0018342 21 8 0,000 0,02140596 0,04665009 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02140596 0,04660851 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02140596 0,04656701 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02140596 0,04652558 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02140596 0,04648423 ! T cell activation GO:0042110 189 84 1,000 0,02180075 0,0472995 ! response to nutrient GO:0007584 135 84 1,000 0,02180075 0,04725753 ! digestion GO:0007586 130 84 1,000 0,02180075 0,04721564 ! hemostasis GO:0007599 165 85 1,000 0,02228736 0,04822678 ! negative regulation of growth GO:0045926 168 85 1,000 0,02228736 0,0481841 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,02228736 0,0481415 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,02228736 0,04809897 ! mitochondrion organization GO:0007005 159 87 1,000 0,02327402 0,05018397 ! amine biosynthetic process GO:0009309 146 88 1,000 0,02377402 0,05121687 ! chromatin assembly GO:0031497 128 88 1,000 0,02377402 0,05117174 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,02377402 0,0511267 ! axon extension GO:0048675 16 9 0,000 0,02404962 0,05167389 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02404962 0,05162848 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02404962 0,05158315 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02404962 0,0515379 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02404962 0,05149273 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02404962 0,05144764 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02404962 0,05140263 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02404962 0,0513577 ! reproductive behavior GO:0019098 22 9 0,000 0,02404962 0,05131285 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02404962 0,05126807 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02404962 0,05122337 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02404962 0,05117875 ! UTP metabolic process GO:0046051 10 9 0,000 0,02404962 0,05113421 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02404962 0,05108975 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02404962 0,05104536 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02404962 0,05100105 ! artery development GO:0060840 25 9 0,000 0,02404962 0,05095682 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02404962 0,05091266 ! regulation of glycolysis GO:0006110 20 9 0,000 0,02404962 0,05086858 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02404962 0,05082458 ! equilibrioception GO:0050957 20 9 0,000 0,02404962 0,05078065 ! chemosensory behavior GO:0007635 21 9 0,000 0,02404962 0,0507368 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02404962 0,05069302 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02404962 0,05064932 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02404962 0,05060569 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02404962 0,05056214 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02404962 0,05051867 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02404962 0,05047527 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02404962 0,05043194 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02404962 0,05038869 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02404962 0,05034551 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02404962 0,05030241 ! protein targeting to ER GO:0045047 25 9 0,000 0,02404962 0,05025938 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02404962 0,05021642 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02404962 0,05017354 ! T cell selection GO:0045058 27 9 0,000 0,02404962 0,05013072 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02404962 0,05008799 ! glycine catabolic process GO:0006546 15 9 0,000 0,02404962 0,05004532 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02404962 0,05000273 ! endosome organization GO:0007032 20 9 0,000 0,02404962 0,04996021 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02404962 0,04991777 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02404962 0,04987539 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02404962 0,04983309 ! mannose metabolic process GO:0006013 13 9 0,000 0,02404962 0,04979086 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02404962 0,0497487 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02404962 0,04970661 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02404962 0,04966459 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02404962 0,04962264 ! receptor clustering GO:0043113 20 9 0,000 0,02404962 0,04958077 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02404962 0,04953896 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02404962 0,04949723 ! retinol metabolic process GO:0042572 20 9 0,000 0,02404962 0,04945556 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02404962 0,04941397 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02404962 0,04937245 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02404962 0,04933099 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02404962 0,04928961 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02404962 0,04924829 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02404962 0,04920704 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02404962 0,04916587 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02404962 0,04912476 ! response to amine stimulus GO:0014075 13 9 0,000 0,02404962 0,04908372 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02404962 0,04904275 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02404962 0,04900184 ! erythrocyte development GO:0048821 17 9 0,000 0,02404962 0,04896101 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02404962 0,04892024 ! renal water homeostasis GO:0003091 15 9 0,000 0,02404962 0,04887954 ! postreplication repair GO:0006301 25 9 0,000 0,02404962 0,04883891 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02404962 0,04879835 ! icosanoid secretion GO:0032309 15 9 0,000 0,02404962 0,04875785 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02404962 0,04871742 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02404962 0,04867706 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02404962 0,04863676 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02404962 0,04859653 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02404962 0,04855637 ! sterol catabolic process GO:0016127 14 9 0,000 0,02404962 0,04851628 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02404962 0,04847625 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02404962 0,04843628 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02404962 0,04839638 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02404962 0,04835655 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02404962 0,04831678 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02404962 0,04827708 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02404962 0,04823745 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02404962 0,04819788 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02404962 0,04815837 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02404962 0,04811893 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02404962 0,04807955 ! purine base metabolic process GO:0006144 25 9 0,000 0,02404962 0,04804024 ! pigment granule transport GO:0051904 17 9 0,000 0,02404962 0,04800099 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02404962 0,0479618 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02404962 0,04792268 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02404962 0,04788363 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02404962 0,04784463 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02404962 0,0478057 ! mitochondrion localization GO:0051646 18 9 0,000 0,02404962 0,04776684 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,0247872 0,04919181 ! gland development GO:0048732 220 91 1,000 0,02530033 0,0501694 ! defense response to bacterium GO:0042742 112 91 1,000 0,02530033 0,05012871 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,02581779 0,05111252 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,02581779 0,05107113 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,02633954 0,05206109 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,02633954 0,052019 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02668621 0,05266107 ! regulation of developmental growth GO:0048638 16 10 0,000 0,02668621 0,05261856 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02668621 0,05257613 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02668621 0,05253376 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02668621 0,05249147 ! associative learning GO:0008306 21 10 0,000 0,02668621 0,05244924 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02668621 0,05240707 ! phosphate transport GO:0006817 24 10 0,000 0,02668621 0,05236498 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02668621 0,05232295 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02668621 0,05228099 ! CTP metabolic process GO:0046036 11 10 0,000 0,02668621 0,0522391 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02668621 0,05219728 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02668621 0,05215552 ! GTP metabolic process GO:0046039 11 10 0,000 0,02668621 0,05211383 ! elastic fiber assembly GO:0048251 17 10 0,000 0,02668621 0,0520722 ! social behavior GO:0035176 29 10 0,000 0,02668621 0,05203065 ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02668621 0,05198915 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02668621 0,05194773 ! androgen metabolic process GO:0008209 17 10 0,000 0,02668621 0,05190637 ! phospholipid efflux GO:0033700 19 10 0,000 0,02668621 0,05186508 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02668621 0,05182385 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02668621 0,05178268 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02668621 0,05174159 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02668621 0,05170055 ! lung alveolus development GO:0048286 26 10 0,000 0,02668621 0,05165959 ! pathogenesis GO:0009405 17 10 0,000 0,02668621 0,05161869 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02668621 0,05157785 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02668621 0,05153707 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02668621 0,05149637 ! endoderm development GO:0007492 18 10 0,000 0,02668621 0,05145572 ! arginine catabolic process GO:0006527 17 10 0,000 0,02668621 0,05141514 ! proline metabolic process GO:0006560 13 10 0,000 0,02668621 0,05137463 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02668621 0,05133417 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02668621 0,05129378 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 34 10 0,000 0,02668621 0,05125346 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02668621 0,0512132 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02668621 0,051173 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02668621 0,05113286 ! B cell proliferation GO:0042100 19 10 0,000 0,02668621 0,05109279 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02668621 0,05105278 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02668621 0,05101283 ! multicellular organism growth GO:0035264 19 10 0,000 0,02668621 0,05097295 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02668621 0,05093312 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02668621 0,05089336 ! ruffle organization GO:0031529 17 10 0,000 0,02668621 0,05085367 ! epithelial cell development GO:0002064 21 10 0,000 0,02668621 0,05081403 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02668621 0,05077445 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02668621 0,05073494 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02668621 0,05069549 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02668621 0,0506561 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02668621 0,05061677 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02668621 0,0505775 ! motor axon guidance GO:0008045 22 10 0,000 0,02668621 0,05053829 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02668621 0,05049915 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02668621 0,05046006 ! protein heterooligomerization GO:0051291 17 10 0,000 0,02668621 0,05042104 ! brain morphogenesis GO:0048854 23 10 0,000 0,02668621 0,05038207 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02668621 0,05034317 ! segment specification GO:0007379 15 10 0,000 0,02668621 0,05030432 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02668621 0,05026554 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02668621 0,05022681 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02668621 0,05018814 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02668621 0,05014954 ! response to dsRNA GO:0043331 23 10 0,000 0,02668621 0,05011099 ! DNA ligation GO:0006266 18 10 0,000 0,02668621 0,0500725 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02668621 0,05003408 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02668621 0,04999571 ! melanosome localization GO:0032400 16 10 0,000 0,02668621 0,04995739 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02668621 0,04991914 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02668621 0,04988095 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02668621 0,04984281 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02668621 0,04980474 ! induction of an organ GO:0001759 17 10 0,000 0,02668621 0,04976672 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02668621 0,04972876 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02668621 0,04969085 ! protein sumoylation GO:0016925 17 10 0,000 0,02668621 0,04965301 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02668621 0,04961522 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02668621 0,04957749 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02668621 0,04953982 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02668621 0,0495022 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02668621 0,04946464 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 14 10 0,000 0,02668621 0,04942714 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02668621 0,0493897 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02668621 0,04935231 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02668621 0,04931498 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02668621 0,0492777 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02668621 0,04924048 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02668621 0,04920332 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02668621 0,04916621 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02668621 0,04912916 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02668621 0,04909217 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,02668621 0,04905523 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,02668621 0,04901835 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02668621 0,04898152 ! blastocyst formation GO:0001825 18 10 0,000 0,02668621 0,04894474 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02668621 0,04890803 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02668621 0,04887136 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02668621 0,04883476 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02668621 0,0487982 ! response to nicotine GO:0035094 20 10 0,000 0,02668621 0,04876171 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02668621 0,04872526 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02668621 0,04868887 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,02739585 0,04994631 ! sex differentiation GO:0007548 171 96 1,000 0,02793034 0,0508828 ! regulation of T cell activation GO:0050863 175 96 1,000 0,02793034 0,05084488 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,02846903 0,05178693 ! transcription initiation GO:0006352 171 97 1,000 0,02846903 0,0517484 ! forebrain development GO:0030900 210 98 1,000 0,02901189 0,05269595 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02931575 0,0532083 ! respiratory burst GO:0045730 17 11 0,000 0,02931575 0,0531688 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02931575 0,05312935 ! neuron fate specification GO:0048665 18 11 0,000 0,02931575 0,05308997 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02931575 0,05305064 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02931575 0,05301138 ! thyroid gland development GO:0030878 26 11 0,000 0,02931575 0,05297217 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,02931575 0,05293302 ! synapsis GO:0007129 14 11 0,000 0,02931575 0,05289392 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02931575 0,05285489 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02931575 0,05281591 ! response to pain GO:0048265 27 11 0,000 0,02931575 0,05277699 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02931575 0,05273812 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02931575 0,05269932 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02931575 0,05266057 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02931575 0,05262187 ! bone resorption GO:0045453 16 11 0,000 0,02931575 0,05258324 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02931575 0,05254466 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02931575 0,05250614 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02931575 0,05246767 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02931575 0,05242926 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02931575 0,05239091 GO:0009075|histidine family amino acid metabolic process, ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02931575 0,05235261 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02931575 0,05231437 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02931575 0,05227618 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02931575 0,05223805 ! UV protection GO:0009650 20 11 0,000 0,02931575 0,05219998 ! adult heart development GO:0007512 16 11 0,000 0,02931575 0,05216196 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02931575 0,052124 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02931575 0,05208609 ! macroautophagy GO:0016236 19 11 0,000 0,02931575 0,05204823 ! temperature homeostasis GO:0001659 18 11 0,000 0,02931575 0,05201044 ! behavioral fear response GO:0001662 27 11 0,000 0,02931575 0,05197269 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02931575 0,051935 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02931575 0,05189737 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02931575 0,05185979 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02931575 0,05182226 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02931575 0,05178479 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02931575 0,05174738 ! regulation of organ growth GO:0046620 14 11 0,000 0,02931575 0,05171001 ! pigment granule localization GO:0051875 20 11 0,000 0,02931575 0,05167271 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02931575 0,05163545 ! vasoconstriction GO:0042310 20 11 0,000 0,02931575 0,05159825 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02931575 0,0515611 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02931575 0,05152401 ! embryonic axis specification GO:0000578 19 11 0,000 0,02931575 0,05148697 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02931575 0,05144998 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02931575 0,05141304 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02931575 0,05137616 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02931575 0,05133933 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02931575 0,05130256 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02931575 0,05126583 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02931575 0,05122916 ! prophase GO:0051324 17 11 0,000 0,02931575 0,05119254 ! nucleosome positioning GO:0016584 15 11 0,000 0,02931575 0,05115598 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02931575 0,05111946 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02931575 0,051083 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02931575 0,05104659 ! apical protein localization GO:0045176 18 11 0,000 0,02931575 0,05101023 ! acid secretion GO:0046717 20 11 0,000 0,02931575 0,05097393 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02931575 0,05093767 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02931575 0,05090147 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02931575 0,05086532 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02931575 0,05082922 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02931575 0,05079317 ! cholesterol efflux GO:0033344 21 11 0,000 0,02931575 0,05075717 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02931575 0,05072122 ! oocyte development GO:0048599 20 11 0,000 0,02931575 0,05068533 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02931575 0,05064948 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 19 11 0,000 0,02931575 0,05061369 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02931575 0,05057794 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02931575 0,05054225 ! activation of innate immune response GO:0002218 16 11 0,000 0,02931575 0,05050661 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02931575 0,05047101 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02931575 0,05043547 ! lysogeny GO:0030069 22 11 0,000 0,02931575 0,05039998 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02931575 0,05036454 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02931575 0,05032914 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02931575 0,0502938 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02931575 0,0502585 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,03193826 0,0547161 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,03193826 0,05467776 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,03193826 0,05463947 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,03193826 0,05460123 ! virus-host interaction GO:0019048 30 12 0,000 0,03193826 0,05456305 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,03193826 0,05452492 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03193826 0,05448685 ! protein complex disassembly GO:0043241 28 12 0,000 0,03193826 0,05444882 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03193826 0,05441085 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,03193826 0,05437294 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,03193826 0,05433507 ! T cell proliferation GO:0042098 32 12 0,000 0,03193826 0,05429726 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03193826 0,0542595 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,03193826 0,0542218 ! ventral spinal cord development GO:0021517 25 12 0,000 0,03193826 0,05418414 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,03193826 0,05414654 ! drug transport GO:0015893 16 12 0,000 0,03193826 0,05410899 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,03193826 0,05407149 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,03193826 0,05403405 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,03193826 0,05399665 ! focal adhesion formation GO:0048041 37 12 0,000 0,03193826 0,05395931 ! mitotic spindle organization GO:0007052 23 12 0,000 0,03193826 0,05392202 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,03193826 0,05388478 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,03193826 0,05384759 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,03193826 0,05381046 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,03193826 0,05377337 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03193826 0,05373634 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,03193826 0,05369936 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,03193826 0,05366242 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03193826 0,05362554 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,03193826 0,05358871 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,03193826 0,05355193 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,03193826 0,0535152 ! snRNA metabolic process GO:0016073 30 12 0,000 0,03193826 0,05347852 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,03193826 0,05344189 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,03193826 0,05340531 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03193826 0,05336879 ! cranial nerve development GO:0021545 23 12 0,000 0,03193826 0,05333231 ! fucose catabolic process GO:0019317 25 12 0,000 0,03193826 0,05329588 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,03193826 0,0532595 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,03193826 0,05322317 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03193826 0,05318689 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,03193826 0,05315066 ! zymogen activation GO:0031638 18 12 0,000 0,03193826 0,05311448 ! T cell homeostasis GO:0043029 28 12 0,000 0,03193826 0,05307834 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,03193826 0,05304226 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,03193826 0,05300623 ! oocyte differentiation GO:0009994 21 12 0,000 0,03193826 0,05297024 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,03193826 0,0529343 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,03193826 0,05289842 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,03193826 0,05286258 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,03193826 0,05282679 ! defense response to fungus GO:0050832 15 12 0,000 0,03193826 0,05279104 ! developmental induction GO:0031128 22 12 0,000 0,03193826 0,05275535 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,03193826 0,05271971 ! lamellipodium assembly GO:0030032 24 12 0,000 0,03193826 0,05268411 ! response to cold GO:0009409 17 12 0,000 0,03193826 0,05264856 ! regulation of synapse organization GO:0050807 18 12 0,000 0,03193826 0,05261306 ! localization within membrane GO:0051668 26 12 0,000 0,03193826 0,0525776 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03455376 0,056845 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03455376 0,05680675 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03455376 0,05676855 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03455376 0,0567304 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03455376 0,0566923 ! peroxisomal transport GO:0043574 28 13 0,000 0,03455376 0,05665425 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03455376 0,05661625 ! cartilage condensation GO:0001502 22 13 0,000 0,03455376 0,0565783 ! organelle fusion GO:0048284 36 13 0,000 0,03455376 0,05654041 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03455376 0,05650256 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,03455376 0,05646477 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,03455376 0,05642703 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,03455376 0,05638933 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03455376 0,05635169 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03455376 0,0563141 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03455376 0,05627655 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03455376 0,05623906 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03455376 0,05620162 ! methionine metabolic process GO:0006555 31 13 0,000 0,03455376 0,05616422 ! plasma membrane organization GO:0007009 27 13 0,000 0,03455376 0,05612688 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03455376 0,05608959 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03455376 0,05605234 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03455376 0,05601515 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,03455376 0,055978 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,03455376 0,05594091 ! cytokine metabolic process GO:0042107 24 13 0,000 0,03455376 0,05590386 ! asymmetric protein localization GO:0008105 24 13 0,000 0,03455376 0,05586686 ! monoamine transport GO:0015844 21 13 0,000 0,03455376 0,05582991 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,03455376 0,05579301 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,03455376 0,05575616 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03455376 0,05571936 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03455376 0,05568261 ! protein homotetramerization GO:0051289 24 13 0,000 0,03455376 0,0556459 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03455376 0,05560924 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03455376 0,05557263 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,03455376 0,05553607 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,03455376 0,05549956 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03455376 0,05546309 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03455376 0,05542668 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,03455376 0,05539031 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03455376 0,05535399 ! histone methylation GO:0016571 29 13 0,000 0,03455376 0,05531771 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,03455376 0,05528149 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03455376 0,05524531 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,03455376 0,05520918 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,03455376 0,05517309 ! spleen development GO:0048536 24 13 0,000 0,03455376 0,05513705 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,03455376 0,05510106 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03455376 0,05506512 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,03455376 0,05502922 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03455376 0,05499337 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,03455376 0,05495757 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03455376 0,05492181 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03455376 0,0548861 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03455376 0,05485044 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03455376 0,05481482 ! insulin secretion GO:0030073 24 13 0,000 0,03455376 0,05477925 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03455376 0,05474373 ! acrosome reaction GO:0007340 19 13 0,000 0,03455376 0,05470825 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03455376 0,05467282 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03455376 0,05463743 ! rRNA transcription GO:0009303 28 14 0,000 0,03716226 0,05872407 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03716226 0,05868611 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03716226 0,0586482 ! water transport GO:0006833 21 14 0,000 0,03716226 0,05861034 GO:0042044|fluid transport, ! non-recombinational repair GO:0000726 29 14 0,000 0,03716226 0,05857252 GO:0006303|double-strand break repair via nonhomologous end joining, ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03716226 0,05853476 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,03716226 0,05849704 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03716226 0,05845938 ! lipid localization GO:0010876 32 14 0,000 0,03716226 0,05842176 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,03716226 0,05838419 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03716226 0,05834666 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03716226 0,05830919 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03716226 0,05827177 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03716226 0,05823439 ! arginine metabolic process GO:0006525 21 14 0,000 0,03716226 0,05819706 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03716226 0,05815978 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03716226 0,05812254 ! regulation of heart rate GO:0002027 25 14 0,000 0,03716226 0,05808536 ! fear response GO:0042596 34 14 0,000 0,03716226 0,05804822 ! organic alcohol transport GO:0015850 29 14 0,000 0,03716226 0,05801112 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03716226 0,05797408 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03716226 0,05793708 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03716226 0,05790013 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03716226 0,05786323 ! bone mineralization GO:0030282 18 14 0,000 0,03716226 0,05782638 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03716226 0,05778957 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03716226 0,05775281 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03716226 0,05771609 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03716226 0,05767942 ! regulation of cellular pH GO:0030641 27 14 0,000 0,03716226 0,0576428 ! ribosome assembly GO:0042255 18 14 0,000 0,03716226 0,05760622 ! cerebellum development GO:0021549 23 14 0,000 0,03716226 0,0575697 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03716226 0,05753321 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03716226 0,05749678 ! response to gamma radiation GO:0010332 30 14 0,000 0,03716226 0,05746039 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03716226 0,05742404 ! NADP metabolic process GO:0006739 24 14 0,000 0,03716226 0,05738774 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03716226 0,05735149 ! oxygen transport GO:0015671 22 14 0,000 0,03716226 0,05731528 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03716226 0,05727912 ! male genitalia development GO:0030539 26 14 0,000 0,03716226 0,05724301 ! regulation of axon extension GO:0030516 43 14 0,000 0,03716226 0,05720694 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03716226 0,05717091 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,03716226 0,05713493 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0397638 0,0610962 ! lactation GO:0007595 30 15 0,000 0,0397638 0,0610578 ! reproductive cellular process GO:0048610 22 15 0,000 0,0397638 0,06101944 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0397638 0,06098114 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,0397638 0,06094288 ! superoxide anion generation GO:0042554 22 15 0,000 0,0397638 0,06090467 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,0397638 0,06086651 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,0397638 0,0608284 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,0397638 0,06079033 ! copper ion transport GO:0006825 22 15 0,000 0,0397638 0,06075232 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,0397638 0,06071435 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,0397638 0,06067642 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,0397638 0,06063855 ! sulfate transport GO:0008272 27 15 0,000 0,0397638 0,06060072 ! response to cAMP GO:0051591 25 15 0,000 0,0397638 0,06056294 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,0397638 0,0605252 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,0397638 0,06048752 ! response to hexose stimulus GO:0009746 25 15 0,000 0,0397638 0,06044988 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,0397638 0,06041228 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,0397638 0,06037474 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,0397638 0,06033724 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,0397638 0,06029978 ! regulation of exocytosis GO:0017157 26 15 0,000 0,0397638 0,06026238 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,0397638 0,06022502 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,0397638 0,0601877 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,0397638 0,06015043 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,0397638 0,06011321 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,0397638 0,06007604 ! regulation of vasodilation GO:0042312 27 15 0,000 0,0397638 0,06003891 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,0397638 0,06000182 ! histone deacetylation GO:0016575 24 15 0,000 0,0397638 0,05996479 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0397638 0,05992779 ! water homeostasis GO:0030104 28 15 0,000 0,0397638 0,05989085 ! cofactor transport GO:0051181 30 15 0,000 0,0397638 0,05985394 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0397638 0,05981709 ! muscle maintenance GO:0046716 26 15 0,000 0,0397638 0,05978028 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,0397638 0,05974351 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0397638 0,05970679 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,0397638 0,05967012 ! heme biosynthetic process GO:0006783 33 15 0,000 0,0397638 0,05963349 ! cell killing GO:0001906 32 15 0,000 0,0397638 0,0595969 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,0397638 0,05956036 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,0397638 0,05952387 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,0397638 0,05948742 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,0397638 0,05945101 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,0397638 0,05941465 ! actin filament polymerization GO:0030041 27 15 0,000 0,0397638 0,05937833 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,0397638 0,05934206 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,04235837 0,06317552 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,04235837 0,06313697 ! positive regulation of cell size GO:0045793 29 16 0,000 0,04235837 0,06309848 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,04235837 0,06306002 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,04235837 0,06302162 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,04235837 0,06298326 ! bone remodeling GO:0046849 28 16 0,000 0,04235837 0,06294495 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,04235837 0,06290669 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04235837 0,06286847 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,04235837 0,0628303 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,04235837 0,06279217 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,04235837 0,06275409 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,04235837 0,06271606 ! startle response GO:0001964 28 16 0,000 0,04235837 0,06267807 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,04235837 0,06264013 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,04235837 0,06260224 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,04235837 0,06256439 ! protein polyubiquitination GO:0000209 41 16 0,000 0,04235837 0,06252659 ! glutamate metabolic process GO:0006536 25 16 0,000 0,04235837 0,06248883 ! pituitary gland development GO:0021983 30 16 0,000 0,04235837 0,06245112 ! response to osmotic stress GO:0006970 27 16 0,000 0,04235837 0,06241345 ! lysosomal transport GO:0007041 31 16 0,000 0,04235837 0,06237583 ! fructose metabolic process GO:0006000 25 16 0,000 0,04235837 0,06233825 ! L-amino acid transport GO:0015807 33 16 0,000 0,04235837 0,06230072 ! stem cell development GO:0048864 46 16 0,000 0,04235837 0,06226324 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04235837 0,0622258 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04235837 0,0621884 ! intermediate filament-based process GO:0045103 36 16 0,000 0,04235837 0,06215105 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,04235837 0,06211375 ! negative regulation of immune response GO:0050777 38 16 0,000 0,04235837 0,06207649 ! axon cargo transport GO:0008088 46 16 0,000 0,04235837 0,06203927 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,04235837 0,0620021 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,04235837 0,06196497 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,04235837 0,06192789 ! neuron recognition GO:0008038 40 16 0,000 0,04235837 0,06189085 ! mRNA splice site selection GO:0006376 44 16 0,000 0,04235837 0,06185386 ! tissue regeneration GO:0042246 27 16 0,000 0,04235837 0,06181691 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,04235837 0,06178 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,04235837 0,06174314 ! biomineral formation GO:0031214 22 16 0,000 0,04235837 0,06170632 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,04235837 0,06166955 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,04235837 0,06163282 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04235837 0,06159613 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,04235837 0,06155949 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,04235837 0,06152289 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,04235837 0,06148633 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,04235837 0,06144982 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04235837 0,06141335 ! peptide hormone processing GO:0016486 27 16 0,000 0,04235837 0,06137693 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,04494601 0,06508779 ! metencephalon development GO:0022037 32 17 0,000 0,04494601 0,06504923 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,04494601 0,06501072 ! signal complex assembly GO:0007172 47 17 0,000 0,04494601 0,06497225 ! gene silencing by RNA GO:0031047 38 17 0,000 0,04494601 0,06493383 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,04494601 0,06489545 ! glial cell development GO:0021782 28 17 0,000 0,04494601 0,06485712 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,04494601 0,06481883 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,04494601 0,06478059 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,04494601 0,06474239 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,04494601 0,06470424 ! myoblast differentiation GO:0045445 50 17 0,000 0,04494601 0,06466614 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,04494601 0,06462808 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,04494601 0,06459006 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,04494601 0,06455209 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,04494601 0,06451416 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,04494601 0,06447628 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,04494601 0,06443844 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,04494601 0,06440065 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,04494601 0,0643629 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,04494601 0,06432519 ! regulation of protein binding GO:0043393 33 17 0,000 0,04494601 0,06428753 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,04494601 0,06424991 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,04494601 0,06421234 ! genitalia development GO:0048806 32 17 0,000 0,04494601 0,06417481 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,04494601 0,06413732 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,04494601 0,06409988 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,04494601 0,06406249 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,04494601 0,06402513 ! steroid catabolic process GO:0006706 34 17 0,000 0,04494601 0,06398782 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,04494601 0,06395055 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,04494601 0,06391333 ! gas transport GO:0015669 26 17 0,000 0,04494601 0,06387615 ! organic cation transport GO:0015695 32 17 0,000 0,04494601 0,06383901 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,04494601 0,06380192 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,04494601 0,06376487 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,04494601 0,06372786 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,04752673 0,06734791 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04752673 0,06730887 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04752673 0,06726987 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04752673 0,06723092 ! adult walking behavior GO:0007628 36 18 0,000 0,04752673 0,06719201 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04752673 0,06715315 ! heart looping GO:0001947 34 18 0,000 0,04752673 0,06711433 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04752673 0,06707556 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04752673 0,06703683 ! centrosome cycle GO:0007098 26 18 0,000 0,04752673 0,06699815 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04752673 0,06695951 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,04752673 0,06692092 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,04752673 0,06688237 ! glycine metabolic process GO:0006544 30 18 0,000 0,04752673 0,06684387 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04752673 0,06680541 ! response to retinoic acid GO:0032526 31 18 0,000 0,04752673 0,06676699 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,04752673 0,06672862 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,04752673 0,06669029 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,04752673 0,06665201 ! DNA integration GO:0015074 32 18 0,000 0,04752673 0,06661377 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,04752673 0,06657557 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,04752673 0,06653742 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04752673 0,06649931 ! neural crest cell migration GO:0001755 41 18 0,000 0,04752673 0,06646124 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04752673 0,06642322 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04752673 0,06638525 GO:0046466|membrane lipid catabolic process, ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04752673 0,06634731 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,04752673 0,06630942 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,04752673 0,06627157 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,04752673 0,06623377 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04752673 0,06619601 ! detection of bacterium GO:0016045 22 18 0,000 0,04752673 0,06615829 ! nerve development GO:0021675 34 18 0,000 0,04752673 0,06612061 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04752673 0,06608298 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,04752673 0,06604539 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,05010054 0,06958251 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,05010054 0,06954297 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,05010054 0,06950348 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,05010054 0,06946404 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,05010054 0,06942463 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,05010054 0,06938528 ! inositol metabolic process GO:0006020 33 19 0,000 0,05010054 0,06934597 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05010054 0,0693067 ! memory GO:0007613 34 19 0,000 0,05010054 0,06926748 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,05010054 0,0692283 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,05010054 0,06918916 GO:0042744|hydrogen peroxide catabolic process, ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,05010054 0,06915007 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,05010054 0,06911103 ! cerebral cortex development GO:0021987 40 19 0,000 0,05010054 0,06907203 ! response to vitamin A GO:0033189 32 19 0,000 0,05010054 0,06903307 ! heme metabolic process GO:0042168 40 19 0,000 0,05010054 0,06899415 ! neuromuscular junction development GO:0007528 43 19 0,000 0,05010054 0,06895528 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,05010054 0,06891646 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,05010054 0,06887768 ! response to fungus GO:0009620 26 19 0,000 0,05010054 0,06883894 ! protein export from nucleus GO:0006611 40 19 0,000 0,05010054 0,06880024 ! heart process GO:0003015 32 19 0,000 0,05010054 0,06876159 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,05010054 0,06872298 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,05010054 0,06868442 ! cellular pigmentation GO:0033059 37 19 0,000 0,05010054 0,06864589 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,05010054 0,06860742 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,05010054 0,06856898 ! vitamin transport GO:0051180 31 19 0,000 0,05010054 0,06853059 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,05010054 0,06849224 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,05010054 0,06845393 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,05010054 0,06841567 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,05010054 0,06837745 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,05010054 0,06833927 ! cilium assembly GO:0042384 38 19 0,000 0,05010054 0,06830113 ! protein secretion GO:0009306 45 20 0,000 0,05266748 0,07176054 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,05266748 0,07172054 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,05266748 0,07168059 ! positive regulation of ossification GO:0045778 50 20 0,000 0,05266748 0,07164067 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,05266748 0,07160081 ! skin development GO:0043588 42 20 0,000 0,05266748 0,07156099 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,05266748 0,07152121 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,05266748 0,07148147 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,05266748 0,07144178 ! response to vitamin GO:0033273 36 20 0,000 0,05266748 0,07140214 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,05266748 0,07136254 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,05266748 0,07132298 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,05266748 0,07128346 ! bile acid metabolic process GO:0008206 34 20 0,000 0,05266748 0,07124399 ! retinoid metabolic process GO:0001523 34 20 0,000 0,05266748 0,07120457 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,05266748 0,07116518 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,05266748 0,07112584 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,05266748 0,07108655 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,05266748 0,0710473 ! actin filament bundle formation GO:0051017 47 20 0,000 0,05266748 0,07100809 ! body fluid secretion GO:0007589 33 20 0,000 0,05266748 0,07096892 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,05266748 0,0709298 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,05266748 0,07089072 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,05266748 0,07085168 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,05266748 0,07081269 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,05266748 0,07077374 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,05266748 0,07073483 ! cell-cell junction organization GO:0045216 43 20 0,000 0,05266748 0,07069596 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,05266748 0,07065714 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,05266748 0,07061836 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,05266748 0,07057962 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,05266748 0,07054093 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,05266748 0,07050227 ! regulation of glucose import GO:0046324 30 20 0,000 0,05266748 0,07046366 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,05266748 0,0704251 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,05266748 0,07038657 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,05266748 0,07034809 ! negative regulation of translation GO:0017148 32 20 0,000 0,05266748 0,07030965 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,05266748 0,07027125 ! regulation of cell killing GO:0031341 46 21 0,000 0,05522755 0,07364678 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,05522755 0,0736066 ! cAMP metabolic process GO:0046058 41 21 0,000 0,05522755 0,07356647 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,05522755 0,07352638 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,05522755 0,07348633 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,05522755 0,07344633 ! ovarian follicle development GO:0001541 39 21 0,000 0,05522755 0,07340637 ! smooth muscle contraction GO:0006939 48 21 0,000 0,05522755 0,07336645 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,05522755 0,07332658 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,05522755 0,07328675 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,05522755 0,07324696 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,05522755 0,07320722 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,05522755 0,07316752 ! sensory perception of pain GO:0019233 33 21 0,000 0,05522755 0,07312786 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,05522755 0,07308825 ! diencephalon development GO:0021536 36 21 0,000 0,05522755 0,07304867 ! collagen fibril organization GO:0030199 62 21 0,000 0,05522755 0,07300915 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,05522755 0,07296966 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,05522755 0,07293022 ! collagen catabolic process GO:0030574 29 21 0,000 0,05522755 0,07289082 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,05522755 0,07285146 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,05522755 0,07281214 ! sperm-egg recognition GO:0035036 23 21 0,000 0,05522755 0,07277287 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,05522755 0,07273364 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,05778077 0,07605519 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,05778077 0,07601423 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,05778077 0,07597332 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,05778077 0,07593245 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,05778077 0,07589163 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 59 22 0,000 0,05778077 0,07585085 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,05778077 0,07581011 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,05778077 0,07576942 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,05778077 0,07572877 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,05778077 0,07568816 ! cellular response to starvation GO:0009267 37 22 0,000 0,05778077 0,0756476 ! vacuolar transport GO:0007034 41 22 0,000 0,05778077 0,07560708 ! central nervous system neuron development GO:0021954 47 22 0,000 0,05778077 0,07556661 ! fucose metabolic process GO:0006004 44 22 0,000 0,05778077 0,07552618 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,05778077 0,07548579 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,05778077 0,07544544 ! ureteric bud development GO:0001657 50 22 0,000 0,05778077 0,07540514 ! cell aging GO:0007569 48 22 0,000 0,05778077 0,07536488 ! stem cell differentiation GO:0048863 57 22 0,000 0,05778077 0,07532467 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,05778077 0,07528449 ! cytolysis GO:0019835 27 22 0,000 0,05778077 0,07524436 ! renal system process GO:0003014 42 22 0,000 0,05778077 0,07520428 ! vasodilation GO:0042311 40 22 0,000 0,05778077 0,07516423 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,05778077 0,07512423 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,05778077 0,07508427 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,05778077 0,07504435 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,05778077 0,07500448 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,05778077 0,07496465 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,05778077 0,07492486 ! sarcomere organization GO:0045214 32 22 0,000 0,05778077 0,07488511 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,05778077 0,0748454 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,05778077 0,07480574 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,05778077 0,07476612 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,05778077 0,07472654 ! gut development GO:0048565 44 22 0,000 0,05778077 0,074687 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,05778077 0,0746475 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,05778077 0,07460805 ! protein stabilization GO:0050821 41 22 0,000 0,05778077 0,07456864 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,06032717 0,07781376 ! gluconeogenesis GO:0006094 38 23 0,000 0,06032717 0,0777727 ! glycerol metabolic process GO:0006071 40 23 0,000 0,06032717 0,07773168 ! viral genome replication GO:0019079 44 23 0,000 0,06032717 0,07769071 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,06032717 0,07764977 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,06032717 0,07760888 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,06032717 0,07756804 ! regeneration GO:0031099 42 23 0,000 0,06032717 0,07752723 ! axis specification GO:0009798 43 23 0,000 0,06032717 0,07748647 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,06032717 0,07744575 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,06032717 0,07740508 ! response to ethanol GO:0045471 47 23 0,000 0,06032717 0,07736445 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,06032717 0,07732386 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,06032717 0,07728331 ! peroxisome organization GO:0007031 43 23 0,000 0,06032717 0,0772428 ! lysosome organization GO:0007040 47 23 0,000 0,06032717 0,07720234 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,06032717 0,07716192 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,06032717 0,07712154 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,06032717 0,07708121 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,06032717 0,07704091 ! fatty acid transport GO:0015908 47 23 0,000 0,06032717 0,07700066 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,06032717 0,07696045 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,06032717 0,07692029 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,06032717 0,07688016 ! cell-cell recognition GO:0009988 28 23 0,000 0,06032717 0,07684008 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,06032717 0,07680004 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,06032717 0,07676004 GO:0006099|tricarboxylic acid cycle, ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,06286675 0,07994975 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,06286675 0,07990816 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,06286675 0,0798666 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,06286675 0,07982509 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,06286675 0,07978362 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,06286675 0,0797422 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,06286675 0,07970082 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,06286675 0,07965948 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,06286675 0,07961818 ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,06286675 0,07957693 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,06286675 0,07953572 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,06286675 0,07949455 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,06286675 0,07945343 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,06286675 0,07941235 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,06286675 0,07937131 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,06286675 0,07933031 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,06286675 0,07928935 ! membrane depolarization GO:0051899 45 24 0,000 0,06286675 0,07924844 ! oogenesis GO:0048477 44 24 0,000 0,06286675 0,07920757 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,06286675 0,07916674 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,06286675 0,07912595 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,06286675 0,07908521 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,06286675 0,07904451 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,06286675 0,07900385 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,06286675 0,07896323 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,06286675 0,07892265 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,06286675 0,07888211 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,06286675 0,07884162 ! regulation of amine transport GO:0051952 41 24 0,000 0,06286675 0,07880117 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,06286675 0,07876076 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,06539954 0,0818919 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,06539954 0,08184994 ! leukocyte adhesion GO:0007159 55 25 0,000 0,06539954 0,08180803 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,06539954 0,08176617 ! phototransduction GO:0007602 37 25 0,000 0,06539954 0,08172434 ! keratinization GO:0031424 37 25 0,000 0,06539954 0,08168256 ! vasculogenesis GO:0001570 49 25 0,000 0,06539954 0,08164082 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,06539954 0,08159913 ! vacuole organization GO:0007033 49 25 0,000 0,06539954 0,08155747 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,06539954 0,08151586 ! receptor metabolic process GO:0043112 53 25 0,000 0,06539954 0,08147429 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,06539954 0,08143277 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,06539954 0,08139128 ! immunoglobulin production GO:0002377 62 25 0,000 0,06539954 0,08134984 GO:0002440|production of molecular mediator of immune response, ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,06539954 0,08130844 ! liver development GO:0001889 55 25 0,000 0,06539954 0,08126708 ! protein tetramerization GO:0051262 57 25 0,000 0,06539954 0,08122577 ! myelination GO:0042552 50 26 0,000 0,06792556 0,0843202 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,06792556 0,08427737 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,06792556 0,08423459 ! molting cycle process GO:0022404 52 26 0,000 0,06792556 0,08419186 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein amino acid alkylation GO:0008213 59 26 0,000 0,06792556 0,08414916 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,06792556 0,08410651 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,06792556 0,08406391 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,06792556 0,08402134 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,06792556 0,08397882 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,06792556 0,08393634 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,06792556 0,08389391 ! osteoblast differentiation GO:0001649 63 26 0,000 0,06792556 0,08385152 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,06792556 0,08380917 ! neural crest cell development GO:0014032 59 26 0,000 0,06792556 0,08376686 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,06792556 0,0837246 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,06792556 0,08368238 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,06792556 0,0836402 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,06792556 0,08359806 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,06792556 0,08355597 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,06792556 0,08351392 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,06792556 0,08347191 ! blastocyst development GO:0001824 50 26 0,000 0,06792556 0,08342994 ! telomere organization GO:0032200 46 26 0,000 0,06792556 0,08338802 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,06792556 0,08334613 ! neural tube closure GO:0001843 58 26 0,000 0,06792556 0,08330429 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,06792556 0,08326249 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,06792556 0,08322074 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,06792556 0,08317902 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,07044483 0,0862208 ! embryonic pattern specification GO:0009880 49 27 0,000 0,07044483 0,08617762 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,07044483 0,08613449 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,07044483 0,0860914 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,07044483 0,08604835 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,07044483 0,08600535 ! iron ion transport GO:0006826 65 27 0,000 0,07044483 0,08596239 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,07044483 0,08591947 ! superoxide metabolic process GO:0006801 41 27 0,000 0,07044483 0,0858766 ! tube lumen formation GO:0035148 59 27 0,000 0,07044483 0,08583377 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,07044483 0,08579098 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,07044483 0,08574824 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,07044483 0,08570553 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,07044483 0,08566287 ! response to starvation GO:0042594 47 27 0,000 0,07044483 0,08562025 ! response to toxin GO:0009636 49 27 0,000 0,07044483 0,08557768 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,07044483 0,08553514 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,07044483 0,08549265 ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,07044483 0,0854502 ! neuron fate commitment GO:0048663 52 28 0,000 0,07295735 0,088454 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,07295735 0,08841012 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,07295735 0,08836629 ! vesicle docking GO:0048278 55 28 0,000 0,07295735 0,0883225 ! circadian rhythm GO:0007623 56 28 0,000 0,07295735 0,08827875 ! dendrite development GO:0016358 67 28 0,000 0,07295735 0,08823505 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,07295735 0,08819139 ! fat cell differentiation GO:0045444 57 28 0,000 0,07295735 0,08814778 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,07295735 0,0881042 ! sperm motility GO:0030317 37 28 0,000 0,07295735 0,08806067 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,07295735 0,08801719 ! base-excision repair GO:0006284 41 28 0,000 0,07295735 0,08797374 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,07295735 0,08793034 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,07295735 0,08788698 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,07295735 0,08784367 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,07295735 0,0878004 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,07295735 0,08775717 ! glutathione metabolic process GO:0006749 42 28 0,000 0,07295735 0,08771398 ! lipid oxidation GO:0034440 48 28 0,000 0,07295735 0,08767083 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,07295735 0,08762773 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,07295735 0,08758467 ! translational initiation GO:0006413 66 29 0,000 0,07546315 0,09054837 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,07546315 0,09050392 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,07546315 0,09045951 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,07546315 0,09041514 ! autophagy GO:0006914 47 29 0,000 0,07546315 0,09037082 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,07546315 0,09032655 ! primary neural tube formation GO:0014020 61 29 0,000 0,07546315 0,09028231 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,07546315 0,09023812 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,07546315 0,09019397 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,07546315 0,09014987 ! synaptogenesis GO:0007416 46 29 0,000 0,07546315 0,09010581 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,07546315 0,09006179 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,07546315 0,09001781 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,07546315 0,08997388 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,07796225 0,09290819 ! phenol metabolic process GO:0018958 56 30 0,000 0,07796225 0,09286289 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,07796225 0,09281763 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,07796225 0,09277242 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,07796225 0,09272725 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,07796225 0,09268213 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,07796225 0,09263705 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,07796225 0,09259202 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,07796225 0,09254703 ! myofibril assembly GO:0030239 50 30 0,000 0,07796225 0,09250208 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,07796225 0,09245717 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,07796225 0,09241231 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,07796225 0,0923675 ! cell fate determination GO:0001709 64 30 0,000 0,07796225 0,09232272 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,07796225 0,09227799 ! phospholipid transport GO:0015914 65 30 0,000 0,07796225 0,09223331 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,07796225 0,09218866 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,07796225 0,09214406 ! tissue homeostasis GO:0001894 50 30 0,000 0,07796225 0,09209951 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,07796225 0,09205499 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,08045467 0,09495205 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,08045467 0,0949062 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,08045467 0,0948604 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,08045467 0,09481464 ! cell junction assembly GO:0034329 85 31 0,000 0,08045467 0,09476892 ! regulation of innate immune response GO:0045088 57 31 0,000 0,08045467 0,09472325 ! ovulation cycle process GO:0022602 55 31 0,000 0,08045467 0,09467763 ! male gonad development GO:0008584 56 31 0,000 0,08045467 0,09463204 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,08045467 0,0945865 ! detection of light stimulus GO:0009583 44 31 0,000 0,08045467 0,09454101 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,08045467 0,09449555 ! natural killer cell activation GO:0030101 50 31 0,000 0,08045467 0,09445014 ! ensheathment of neurons GO:0007272 64 31 0,000 0,08045467 0,09440478 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,08045467 0,09435946 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,08045467 0,09431418 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,08045467 0,09426894 ! eye morphogenesis GO:0048592 65 31 0,000 0,08045467 0,09422375 ! response to heat GO:0009408 54 31 0,000 0,08045467 0,09417861 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,08045467 0,0941335 ! collagen metabolic process GO:0032963 49 32 0,000 0,08294041 0,09699542 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,08294041 0,09694901 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,08294041 0,09690265 ! metanephros development GO:0001656 81 32 0,000 0,08294041 0,09685632 ! muscle cell development GO:0055001 52 32 0,000 0,08294041 0,09681005 ! mesoderm formation GO:0001707 73 32 0,000 0,08294041 0,09676382 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,08294041 0,09671763 ! ovulation cycle GO:0042698 57 32 0,000 0,08294041 0,09667148 ! peripheral nervous system development GO:0007422 68 32 0,000 0,08294041 0,09662538 ! BMP signaling pathway GO:0030509 71 32 0,000 0,08294041 0,09657933 ! hindbrain development GO:0030902 65 32 0,000 0,08294041 0,09653332 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,08294041 0,09648735 ! regulation of pH GO:0006885 56 33 0,000 0,08541951 0,09932407 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,08541951 0,09927682 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,08541951 0,09922961 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,08541951 0,09918245 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,08541951 0,09913533 ! response to ionizing radiation GO:0010212 74 33 0,000 0,08541951 0,09908826 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,08541951 0,09904123 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,08541951 0,09899424 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,08541951 0,09894731 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,08541951 0,09890041 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,08789198 0,10171487 ! glial cell differentiation GO:0010001 67 34 0,000 0,08789198 0,10166671 ! post-embryonic development GO:0009791 76 34 0,000 0,08789198 0,1016186 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,08789198 0,10157053 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,08789198 0,10152251 ! spliceosome assembly GO:0000245 75 34 0,000 0,08789198 0,10147453 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,08789198 0,10142659 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,08789198 0,10137871 ! formation of primary germ layer GO:0001704 76 34 0,000 0,08789198 0,10133086 ! cell fate specification GO:0001708 56 34 0,000 0,08789198 0,10128307 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,08789198 0,10123531 ! adult locomotory behavior GO:0008344 62 34 0,000 0,08789198 0,10118761 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,09035783 0,10397747 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,09035783 0,10392852 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,09035783 0,10387961 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,09035783 0,10383075 ! membrane docking GO:0022406 69 35 0,000 0,09035783 0,10378193 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,09035783 0,10373316 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,09035783 0,10368444 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,09035783 0,10363576 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,09035783 0,10358713 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,09035783 0,10353854 ! ceramide metabolic process GO:0006672 72 35 0,000 0,09035783 0,10349 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,09035783 0,10344151 ! placenta development GO:0001890 53 35 0,000 0,09035783 0,10339306 ! regulation of muscle development GO:0048634 82 36 0,000 0,09281708 0,10615737 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,09281708 0,10610769 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,09281708 0,10605806 ! positive regulation of cell development GO:0010720 85 36 0,000 0,09281708 0,10600848 ! protein targeting to membrane GO:0006612 75 36 0,000 0,09281708 0,10595894 ! regulation of proteolysis GO:0030162 77 36 0,000 0,09281708 0,10590945 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,09281708 0,10586001 ! aerobic respiration GO:0009060 56 36 0,000 0,09281708 0,10581061 ! cytokine production GO:0001816 68 36 0,000 0,09281708 0,10576126 ! embryonic organ development GO:0048568 67 36 0,000 0,09281708 0,10571195 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,09281708 0,10566269 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,09281708 0,10561348 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,09526976 0,10835382 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,09526976 0,1083034 ! odontogenesis GO:0042476 74 37 0,000 0,09526976 0,10825303 ! actomyosin structure organization GO:0031032 68 37 0,000 0,09526976 0,1082027 ! cell junction organization GO:0034330 96 37 0,000 0,09526976 0,10815242 ! tissue remodeling GO:0048771 78 37 0,000 0,09526976 0,10810219 ! female gonad development GO:0008585 71 37 0,000 0,09526976 0,108052 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,09526976 0,10800186 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,09526976 0,10795177 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,09526976 0,10790172 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,09771587 0,11062088 ! organic anion transport GO:0015711 82 38 0,000 0,09771587 0,11056965 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,09771587 0,11051846 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,09771587 0,11046731 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,09771587 0,11041622 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,09771587 0,11036517 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,09771587 0,11031417 ! regulation of protein stability GO:0031647 77 38 0,000 0,09771587 0,11026322 ! spermatid development GO:0007286 69 38 0,000 0,09771587 0,11021231 ! glycogen metabolic process GO:0005977 63 38 0,000 0,09771587 0,11016145 ! pigment metabolic process GO:0042440 87 38 0,000 0,09771587 0,11011064 ! neural tube formation GO:0001841 79 38 0,000 0,09771587 0,11005987 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,10015544 0,11275564 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,10015544 0,1127037 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,10015544 0,11265181 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,10015544 0,11259997 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,10015544 0,11254817 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,10015544 0,11249643 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,10015544 0,11244473 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,10015544 0,11239308 ! glucan metabolic process GO:0044042 64 39 0,000 0,10015544 0,11234147 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,10258848 0,11501774 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,10258848 0,11496498 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,10258848 0,11491226 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,10258848 0,1148596 GO:0046660|female sex differentiation, ! mismatch repair GO:0006298 58 40 0,000 0,10258848 0,11480698 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,10258848 0,11475442 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,10258848 0,1147019 ! RNA export from nucleus GO:0006405 61 41 0,000 0,10501501 0,11736123 ! mRNA catabolic process GO:0006402 79 41 0,000 0,10501501 0,11730757 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,10501501 0,11725396 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,10501501 0,11720039 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,10501501 0,11714688 ! gliogenesis GO:0042063 91 41 0,000 0,10501501 0,11709341 ! feeding behavior GO:0007631 69 41 0,000 0,10501501 0,11703999 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,10501501 0,11698662 ! mesenchymal cell development GO:0014031 94 41 0,000 0,10501501 0,1169333 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,10501501 0,11688003 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,10501501 0,1168268 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,10501501 0,11677363 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,10501501 0,1167205 ! RNA modification GO:0009451 64 41 0,000 0,10501501 0,11666742 ! organic ether metabolic process GO:0018904 59 42 0,000 0,10743504 0,11930173 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,10743504 0,11924753 ! T cell differentiation GO:0030217 93 42 0,000 0,10743504 0,11919337 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,10743504 0,11913927 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,10743504 0,11908521 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,10743504 0,11903121 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,1098486 0,12165011 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,1098486 0,12159499 ! regulation of tube size GO:0035150 76 43 0,000 0,1098486 0,12153992 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,1098486 0,1214849 ! glucose transport GO:0015758 66 43 0,000 0,1098486 0,12142993 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,1098486 0,12137501 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,1098486 0,12132013 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,1098486 0,12126531 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,1098486 0,12121054 ! ion transmembrane transport GO:0034220 79 43 0,000 0,1098486 0,12115582 ! neuron migration GO:0001764 85 43 0,000 0,1098486 0,12110114 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,1098486 0,12104652 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,11225571 0,12364323 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,11225571 0,12358751 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,11225571 0,12353184 ! hexose transport GO:0008645 68 44 0,000 0,11225571 0,12347622 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,11225571 0,12342065 ! striated muscle contraction GO:0006941 85 44 0,000 0,11225571 0,12336513 ! phagocytosis GO:0006909 105 44 0,000 0,11225571 0,12330966 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,11225571 0,12325424 ! double-strand break repair GO:0006302 85 44 0,000 0,11225571 0,12319887 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,11465637 0,12577705 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,11465637 0,1257206 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,11465637 0,1256642 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! B cell differentiation GO:0030183 124 45 0,000 0,11465637 0,12560785 ! female gamete generation GO:0007292 71 45 0,000 0,11465637 0,12555155 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,11465637 0,1254953 ! polyol metabolic process GO:0019751 77 45 0,000 0,11465637 0,1254391 ! developmental growth GO:0048589 88 45 0,000 0,11465637 0,12538295 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,1170506 0,1279439 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,1170506 0,12788668 ! glycolysis GO:0006096 71 46 0,000 0,1170506 0,12782951 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,1170506 0,1277724 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,1170506 0,12771533 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,1170506 0,12765831 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,1170506 0,12760135 ! cell growth GO:0016049 90 46 0,000 0,1170506 0,12754443 ! neural tube development GO:0021915 91 47 0,000 0,11943843 0,13008831 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,11943843 0,13003034 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,12181987 0,13256389 ! mitochondrial transport GO:0006839 94 48 0,000 0,12181987 0,13250487 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,12181987 0,1324459 ! endosome transport GO:0016197 127 48 0,000 0,12181987 0,13238698 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,12181987 0,13232812 ! male sex differentiation GO:0046661 93 48 0,000 0,12181987 0,13226931 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,12181987 0,13221055 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,12181987 0,13215184 ! response to calcium ion GO:0051592 94 49 0,000 0,12419493 0,13466854 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,12419493 0,13460879 ! JNK cascade GO:0007254 106 49 0,000 0,12419493 0,1345491 ! protein homooligomerization GO:0051260 84 49 0,000 0,12419493 0,13448946 ! regulation of action potential GO:0001508 102 50 0,000 0,12656364 0,13699379 ! regulation of ion transport GO:0043269 86 50 0,000 0,12656364 0,13693312 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,12656364 0,1368725 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,12656364 0,13681194 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,12656364 0,13675143 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,12656364 0,13669097 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,12892601 0,13918084 ! peptide metabolic process GO:0006518 80 51 0,000 0,12892601 0,13911936 ! response to temperature stimulus GO:0009266 84 51 0,000 0,12892601 0,13905794 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,12892601 0,13899658 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,13128205 0,14147422 ! Notch signaling pathway GO:0007219 111 52 0,000 0,13128205 0,14141184 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,13128205 0,14134952 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,13128205 0,14128725 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,13128205 0,14122504 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,13128205 0,14116288 ! excretion GO:0007588 87 52 0,000 0,13128205 0,14110077 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,13128205 0,14103872 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,13128205 0,14097673 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,13128205 0,14091479 ! amino acid activation GO:0043038 98 52 0,000 0,13128205 0,1408529 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,13363179 0,14331101 ! positive regulation of growth GO:0045927 96 53 0,000 0,13363179 0,14324812 ! inner ear development GO:0048839 89 53 0,000 0,13363179 0,14318529 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,13363179 0,14312252 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,13363179 0,1430598 ! cartilage development GO:0051216 99 53 0,000 0,13363179 0,14299714 ! synapse organization GO:0050808 102 53 0,000 0,13363179 0,14293453 ! regulation of translational initiation GO:0006446 87 54 0,000 0,13597524 0,14537747 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,13597524 0,14531387 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,13597524 0,14525033 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,13597524 0,14518685 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,13597524 0,14512342 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,13597524 0,14506005 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,13597524 0,14499673 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,13597524 0,14493347 ! RNA catabolic process GO:0006401 103 55 0,000 0,13831242 0,14736033 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,13831242 0,14729609 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,13831242 0,14723191 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,13831242 0,14716779 ! cell recognition GO:0008037 98 55 0,000 0,13831242 0,14710372 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,13831242 0,1470397 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,13831242 0,14697574 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,13831242 0,14691184 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,14064334 0,14932276 ! glucose catabolic process GO:0006007 88 56 0,000 0,14064334 0,14925789 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,14064334 0,14919308 ! RNA elongation GO:0006354 90 56 0,000 0,14064334 0,14912833 ! chloride transport GO:0006821 102 57 0,000 0,14296802 0,15152749 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,14296802 0,15146178 ! heart morphogenesis GO:0003007 105 57 0,000 0,14296802 0,15139613 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,14296802 0,15133053 ! regulation of actin filament length GO:0030832 118 58 0,000 0,14528647 0,153718 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,14528647 0,15365145 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,14528647 0,15358497 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,14528647 0,15351854 ! aging GO:0007568 112 58 0,000 0,14528647 0,15345216 ! gastrulation GO:0007369 122 58 0,000 0,14528647 0,15338585 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,14528647 0,15331959 ! nuclear export GO:0051168 110 59 0,000 0,14759872 0,15569244 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,14990478 0,15805671 ! regulation of endocytosis GO:0030100 104 60 0,000 0,14990478 0,15798852 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,14990478 0,15792039 ! adult behavior GO:0030534 104 60 0,000 0,14990478 0,15785232 ! regulation of cellular component size GO:0032535 125 61 0,000 0,15220467 0,16020509 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,15220467 0,16013609 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,15220467 0,16006716 ! regulation of heart contraction GO:0008016 123 61 0,000 0,15220467 0,15999828 ! camera-type eye development GO:0043010 126 61 0,000 0,15220467 0,15992946 ! proton transport GO:0015992 117 61 0,000 0,15220467 0,15986071 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,1544984 0,16220008 ! tRNA processing GO:0008033 102 62 0,000 0,1544984 0,16213041 ! mesoderm development GO:0007498 128 63 0,000 0,15678598 0,16446035 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,15678598 0,16438977 ! hydrogen transport GO:0006818 121 64 0,000 0,15906745 0,16671033 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,15906745 0,16663884 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,15906745 0,16656741 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,1613428 0,16887766 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,1613428 0,16880533 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,1613428 0,16873307 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,1613428 0,16866087 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,1613428 0,16858873 ! activation of MAPK activity GO:0000187 124 67 0,000 0,16587524 0,17325063 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,16587524 0,17317659 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,16587524 0,17310261 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,16587524 0,1730287 ! secondary metabolic process GO:0019748 125 67 0,000 0,16587524 0,17295485 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,16813237 0,17523352 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,16813237 0,17515879 ! hexose catabolic process GO:0019320 113 68 0,000 0,16813237 0,17508413 ! extracellular matrix organization GO:0030198 146 68 0,000 0,16813237 0,17500953 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,16813237 0,174935 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 137 68 0,000 0,16813237 0,17486052 ! adaptive immune response GO:0002250 126 68 0,000 0,16813237 0,17478612 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,16813237 0,17471177 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,17038345 0,17697566 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,17038345 0,17690045 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,17038345 0,1768253 ! single fertilization GO:0007338 83 69 0,000 0,17038345 0,17675022 ! cell redox homeostasis GO:0045454 114 70 0,000 0,1726285 0,17900315 ! germ cell development GO:0007281 133 70 0,000 0,1726285 0,1789272 ! activation of immune response GO:0002253 120 70 0,000 0,1726285 0,17885132 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,1726285 0,17877551 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,17486754 0,18101754 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,17486754 0,18094087 ! appendage morphogenesis GO:0035107 150 72 0,000 0,17710058 0,18317388 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,17710058 0,18309637 ! B cell activation GO:0042113 179 72 0,000 0,17710058 0,18301891 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,17710058 0,18294153 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,17710058 0,18286421 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,17710058 0,18278695 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,17710058 0,18270976 ! appendage development GO:0048736 151 73 0,000 0,17932764 0,18492926 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,17932764 0,18485123 ! amino acid transport GO:0006865 148 74 0,000 0,18154874 0,18706182 ! transition metal ion transport GO:0000041 143 75 0,000 0,18376389 0,18926441 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,18376389 0,18918465 ! axon guidance GO:0007411 162 75 0,000 0,18376389 0,18910496 ! rhythmic process GO:0048511 142 75 0,000 0,18376389 0,18902534 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,1859731 0,19121729 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,1859731 0,19113685 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,1859731 0,19105647 ! regulation of blood pressure GO:0008217 134 76 0,000 0,1859731 0,19097616 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,1859731 0,19089592 ! amine catabolic process GO:0009310 136 77 0,000 0,1881764 0,19307642 ! neurotransmitter transport GO:0006836 142 77 0,000 0,1881764 0,19299536 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,1881764 0,19291437 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,1881764 0,19283345 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,1881764 0,1927526 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,1881764 0,19267181 ! regulation of catabolic process GO:0009894 173 77 0,000 0,1881764 0,1925911 ! antigen processing and presentation GO:0019882 117 78 0,000 0,1903738 0,19475845 ! fertilization GO:0009566 99 78 0,000 0,1903738 0,19467693 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,19256531 0,19683558 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,19256531 0,19675326 ! protein oligomerization GO:0051259 149 79 0,000 0,19256531 0,19667101 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,19256531 0,19658882 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,19475095 0,19873708 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,19475095 0,1986541 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,19693073 0,20079373 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,19910468 0,20292563 ! protein import into nucleus GO:0006606 174 82 0,000 0,19910468 0,20284101 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,2012728 0,20496434 ! exocytosis GO:0006887 153 83 0,000 0,2012728 0,20487894 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,2012728 0,20479361 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,2012728 0,20470835 ! nuclear import GO:0051170 177 83 0,000 0,2012728 0,20462316 ! inorganic anion transport GO:0015698 156 83 0,000 0,2012728 0,20453804 ! response to metal ion GO:0010038 158 84 0,000 0,20343512 0,20664947 ! regulation of ligase activity GO:0051340 147 84 0,000 0,20343512 0,20656359 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,20559164 0,20866654 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,20559164 0,20857989 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,20774238 0,2106744 ! regulation of lyase activity GO:0051339 169 86 0,000 0,20774238 0,21058698 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,20988736 0,21267309 ! alcohol catabolic process GO:0046164 142 87 0,000 0,20988736 0,21258492 ! nucleosome assembly GO:0006334 126 87 0,000 0,20988736 0,21249682 ! cellular respiration GO:0045333 143 88 0,000 0,21202659 0,21457372 ! sensory perception of smell GO:0007608 117 88 0,000 0,21202659 0,21448487 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,2141601 0,21655344 ! tube morphogenesis GO:0035239 194 89 0,000 0,2141601 0,21646385 ! cellular defense response GO:0006968 123 89 0,000 0,2141601 0,21637432 ! protein localization in nucleus GO:0034504 192 89 0,000 0,2141601 0,21628488 ! regulation of neurological system process GO:0031644 175 89 0,000 0,2141601 0,2161955 ! response to inorganic substance GO:0010035 173 90 0,000 0,21628788 0,21825332 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,21628788 0,21816321 ! response to unfolded protein GO:0006986 139 90 0,000 0,21628788 0,21807317 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,21840997 0,22012192 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,21840997 0,22003115 ! bone development GO:0060348 206 92 0,000 0,22052636 0,22207168 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,22263709 0,22410482 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,22263709 0,22401252 ! vitamin metabolic process GO:0006766 153 93 0,000 0,22263709 0,2239203 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,22474216 0,22594448 ! female pregnancy GO:0007565 166 94 0,000 0,22474216 0,22585154 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,22474216 0,22575867 ! regulation of membrane potential GO:0042391 179 94 0,000 0,22474216 0,22566588 ! nucleosome organization GO:0034728 143 95 0,000 0,22684159 0,22768036 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,22684159 0,22758686 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,22684159 0,22749343 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,22684159 0,22740008 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,22684159 0,22730681 ! response to protein stimulus GO:0051789 158 96 0,000 0,22893539 0,22931085 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,23310618 0,23339278 ! mRNA transport GO:0051028 185 100 0,000 0,23725464 0,23744903 ! positive regulation of immune response GO:0050778 175 100 0,000 0,23725464 0,23735179 ! hormone metabolic process GO:0042445 171 100 0,000 0,23725464 0,23725464