pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1034-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 1,186E-10 2,854E-07 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 4,000 7,628E-10 9,176E-07 ! natural killer cell mediated immunity GO:0002228 18 10 3,000 4,939E-09 3,961E-06 GO:0042267|natural killer cell mediated cytotoxicity, ! leukocyte mediated cytotoxicity GO:0001909 26 12 3,000 1,16E-08 6,979E-06 ! protein oligomerization GO:0051259 139 78 5,000 2,39E-08 1,15E-05 ! cell killing GO:0001906 29 15 3,000 3,183E-08 1,277E-05 ! positive regulation of vasoconstriction GO:0045907 9 5 2,000 1,097E-07 3,772E-05 ! inactivation of MAPK activity GO:0000188 39 21 3,000 1,382E-07 4,155E-05 ! nuclear migration GO:0007097 12 6 2,000 2,191E-07 5,857E-05 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 2,191E-07 5,272E-05 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of microtubule polymerization GO:0031116 13 6 2,000 2,191E-07 4,792E-05 ! regulation of protein complex assembly GO:0043254 117 61 4,000 2,725E-07 5,463E-05 ! regulation of lipid metabolic process GO:0019216 115 63 4,000 3,208E-07 5,938E-05 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 3,828E-07 6,579E-05 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 2,000 3,828E-07 6,14E-05 ! macrophage differentiation GO:0030225 11 7 2,000 3,828E-07 5,757E-05 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 2,000 3,828E-07 5,418E-05 ! regulation of microtubule polymerization GO:0031113 15 7 2,000 3,828E-07 5,117E-05 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 4,377E-07 5,543E-05 ! negative regulation of kinase activity GO:0033673 131 68 4,000 4,717E-07 5,674E-05 ! establishment of nucleus localization GO:0040023 16 8 2,000 6,115E-07 7,006E-05 ! negative regulation of transferase activity GO:0051348 140 72 4,000 6,287E-07 6,876E-05 ! spindle organization GO:0007051 46 32 3,000 8,147E-07 8,523E-05 ! negative regulation of MAP kinase activity GO:0043407 69 32 3,000 8,147E-07 8,168E-05 ! regulation of epithelial cell differentiation GO:0030856 14 9 2,000 9,158E-07 8,814E-05 ! gas homeostasis GO:0033483 16 9 2,000 9,158E-07 8,475E-05 ! regulation of peptidase activity GO:0052547 134 79 4,000 1E-06 8,915E-05 ! negative regulation of MAPKKK cascade GO:0043409 20 10 2,000 1,306E-06 1,122E-04 ! nucleus localization GO:0051647 19 11 2,000 1,793E-06 1,488E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 2,387E-06 1,914E-04 ! gland morphogenesis GO:0022612 29 12 2,000 2,387E-06 1,853E-04 ! lipid localization GO:0010876 28 13 2,000 3,098E-06 2,329E-04 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 25 13 2,000 3,098E-06 2,259E-04 ! protein homooligomerization GO:0051260 76 47 3,000 3,939E-06 2,788E-04 ! regulation of vasodilation GO:0042312 26 15 2,000 4,913E-06 3,377E-04 ! filopodium assembly GO:0046847 32 16 2,000 6,036E-06 4,034E-04 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 2,000 6,036E-06 3,925E-04 ! response to UV GO:0009411 104 53 3,000 6,402E-06 4,053E-04 ! positive regulation of protein complex assembly GO:0031334 32 17 2,000 7,318E-06 4,515E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 7,318E-06 4,402E-04 ! microspike assembly GO:0030035 36 17 2,000 7,318E-06 4,294E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 8,578E-06 4,914E-04 ! regulation of fatty acid metabolic process GO:0019217 38 20 2,000 1,221E-05 6,831E-04 ! lymphocyte mediated immunity GO:0002449 114 64 3,000 1,363E-05 7,455E-04 ! regulation of vasoconstriction GO:0019229 39 21 2,000 1,422E-05 7,604E-04 ! cell projection assembly GO:0030031 120 66 3,000 1,541E-05 8,062E-04 ! negative regulation of cell growth GO:0030308 132 67 3,000 1,636E-05 8,377E-04 ! positive regulation of cytoskeleton organization GO:0051495 48 22 2,000 1,644E-05 8,24E-04 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 1,644E-05 8,072E-04 ! negative regulation of cell size GO:0045792 134 69 3,000 1,839E-05 8,851E-04 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 1,888E-05 8,905E-04 ! membrane depolarization GO:0051899 39 24 2,000 2,154E-05 9,965E-04 ! protein tetramerization GO:0051262 52 24 2,000 2,154E-05 9,777E-04 ! leukocyte mediated immunity GO:0002443 128 74 3,000 2,428E-05 1,082E-03 ! vasculogenesis GO:0001570 46 25 2,000 2,443E-05 1,069E-03 ! regulation of smooth muscle contraction GO:0006940 43 25 2,000 2,443E-05 1,05E-03 ! interaction with host GO:0051701 62 25 2,000 2,443E-05 1,031E-03 ! regulation of blood coagulation GO:0030193 40 25 2,000 2,443E-05 1,014E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 2,758E-05 1,125E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 2,758E-05 1,106E-03 ! regulation of cellular ketone metabolic process GO:0010565 44 26 2,000 2,758E-05 1,088E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 3,097E-05 1,202E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 3,097E-05 1,183E-03 ! response to hypoxia GO:0001666 171 81 3,000 3,469E-05 1,304E-03 ! response to oxygen levels GO:0070482 176 83 3,000 3,818E-05 1,413E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 3,857E-05 1,406E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 3,857E-05 1,385E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 3,857E-05 1,365E-03 ! regulation of coagulation GO:0050818 46 29 2,000 3,857E-05 1,345E-03 ! negative regulation of growth GO:0045926 155 84 3,000 4,002E-05 1,376E-03 ! negative regulation of protein kinase cascade GO:0010741 68 30 2,000 4,278E-05 1,45E-03 ! cholesterol homeostasis GO:0042632 53 31 2,000 4,729E-05 1,58E-03 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 43 31 2,000 4,729E-05 1,559E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 5,001E-05 1,626E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 5,001E-05 1,604E-03 ! microvillus organization GO:0032528 7 5 1,000 5,001E-05 1,583E-03 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 5,001E-05 1,563E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 5,001E-05 1,543E-03 ! cholesterol transport GO:0030301 56 32 2,000 5,21E-05 1,587E-03 ! sterol transport GO:0015918 57 33 2,000 5,722E-05 1,721E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 6,265E-05 1,861E-03 ! leukocyte differentiation GO:0002521 202 96 3,000 6,752E-05 1,981E-03 ! neutral lipid metabolic process GO:0006638 50 35 2,000 6,842E-05 1,983E-03 GO:0006639|acylglycerol metabolic process, ! regulation of microtubule-based process GO:0032886 78 35 2,000 6,842E-05 1,96E-03 ! male sex determination GO:0030238 15 6 1,000 7,491E-05 2,12E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 7,491E-05 2,096E-03 ! skeletal muscle tissue development GO:0007519 186 99 3,000 7,612E-05 2,105E-03 GO:0060538|skeletal muscle organ development, ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 8,096E-05 2,213E-03 ! tissue remodeling GO:0048771 76 37 2,000 8,096E-05 2,189E-03 ! glycerol ether metabolic process GO:0006662 53 37 2,000 8,096E-05 2,164E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 8,096E-05 2,141E-03 ! lipid homeostasis GO:0055088 67 38 2,000 8,776E-05 2,295E-03 ! mammary gland development GO:0030879 86 39 2,000 9,492E-05 2,456E-03 ! organic ether metabolic process GO:0018904 55 39 2,000 9,492E-05 2,429E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 1,047E-04 2,652E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,047E-04 2,624E-03 ! vesicle fusion GO:0006906 17 7 1,000 1,047E-04 2,597E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,047E-04 2,571E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,047E-04 2,545E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,047E-04 2,52E-03 ! response to tumor cell GO:0002347 13 7 1,000 1,047E-04 2,495E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,047E-04 2,47E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,394E-04 3,257E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,394E-04 3,225E-03 ! ER overload response GO:0006983 12 8 1,000 1,394E-04 3,195E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,394E-04 3,165E-03 ! regulation of JAK-STAT cascade GO:0046425 70 45 2,000 1,46E-04 3,282E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 1,46E-04 3,252E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,559E-04 3,441E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 1,559E-04 3,41E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 1,559E-04 3,379E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 1,79E-04 3,845E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,79E-04 3,811E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 1,79E-04 3,778E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,79E-04 3,745E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 1,79E-04 3,713E-03 ! regulation of cell projection organization GO:0031344 121 50 2,000 2E-04 4,112E-03 ! vesicle organization GO:0016050 107 51 2,000 2,121E-04 4,325E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 2,234E-04 4,517E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,234E-04 4,479E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,234E-04 4,442E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,234E-04 4,406E-03 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 2,234E-04 4,37E-03 ! regulation of muscle contraction GO:0006937 81 52 2,000 2,248E-04 4,361E-03 ! regulation of protein polymerization GO:0032271 103 53 2,000 2,379E-04 4,578E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,727E-04 5,207E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,727E-04 5,166E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 2,727E-04 5,125E-03 ! nitric oxide metabolic process GO:0046209 15 11 1,000 2,727E-04 5,085E-03 GO:0006809|nitric oxide biosynthetic process, ! regulation of embryonic development GO:0045995 27 11 1,000 2,727E-04 5,046E-03 ! regulation of DNA replication GO:0006275 101 56 2,000 2,801E-04 5,144E-03 ! positive regulation of organelle organization GO:0010638 100 56 2,000 2,801E-04 5,106E-03 ! positive regulation of cell migration GO:0030335 126 57 2,000 2,952E-04 5,34E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 3,267E-04 5,866E-03 ! virus-host interaction GO:0019048 29 12 1,000 3,267E-04 5,823E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 3,267E-04 5,78E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 3,267E-04 5,738E-03 ! entry into host cell GO:0030260 32 12 1,000 3,267E-04 5,696E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 3,267E-04 5,655E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,267E-04 5,615E-03 ! establishment of organelle localization GO:0051656 109 59 2,000 3,269E-04 5,578E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 3,436E-04 5,821E-03 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 3,607E-04 6,07E-03 ! viral reproductive process GO:0022415 126 62 2,000 3,785E-04 6,324E-03 ! organelle fusion GO:0048284 32 13 1,000 3,856E-04 6,398E-03 ! plasma membrane organization GO:0007009 24 13 1,000 3,856E-04 6,354E-03 ! Golgi organization GO:0007030 24 13 1,000 3,856E-04 6,311E-03 ! response to X-ray GO:0010165 25 13 1,000 3,856E-04 6,268E-03 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 3,856E-04 6,226E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 3,856E-04 6,184E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 3,856E-04 6,143E-03 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,856E-04 6,103E-03 ! positive regulation of cell motion GO:0051272 146 64 2,000 4,156E-04 6,536E-03 ! myeloid cell differentiation GO:0030099 111 65 2,000 4,35E-04 6,796E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 4,492E-04 6,972E-03 ! response to gamma radiation GO:0010332 28 14 1,000 4,492E-04 6,927E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 4,492E-04 6,883E-03 ! viral reproduction GO:0016032 134 68 2,000 4,967E-04 7,564E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 5,175E-04 7,831E-03 ! G1/S transition checkpoint GO:0031575 40 15 1,000 5,175E-04 7,782E-03 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 5,175E-04 7,734E-03 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 5,637E-04 8,373E-03 ! regulation of caspase activity GO:0043281 122 72 2,000 5,873E-04 8,669E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 5,906E-04 8,664E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 5,906E-04 8,612E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 5,906E-04 8,56E-03 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 6,363E-04 9,167E-03 ! organelle localization GO:0051640 136 74 2,000 6,363E-04 9,113E-03 ! signal complex assembly GO:0007172 41 17 1,000 6,683E-04 9,515E-03 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 7,508E-04 0,01062588 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 7,508E-04 0,01056374 ! lipid phosphorylation GO:0046834 35 19 1,000 8,379E-04 0,01172079 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 8,582E-04 0,01193483 ! protein amino acid acetylation GO:0006473 39 20 1,000 9,296E-04 0,01285465 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 9,296E-04 0,01278119 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 9,296E-04 0,01270857 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 9,296E-04 0,01263677 ! cellular response to starvation GO:0009267 33 20 1,000 9,296E-04 0,01256578 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 9,296E-04 0,01249558 ! cell aging GO:0007569 44 21 1,000 1,026E-03 0,01371417 ! gland development GO:0048732 206 88 2,000 1,053E-03 0,01399917 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 1,127E-03 0,01489807 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 1,127E-03 0,01481666 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 1,127E-03 0,01473614 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 1,127E-03 0,01465648 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,127E-03 0,01457769 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,127E-03 0,01449973 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,232E-03 0,01577318 ! sex determination GO:0007530 47 23 1,000 1,232E-03 0,01568972 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 1,232E-03 0,01560715 ! platelet activation GO:0030168 37 23 1,000 1,232E-03 0,01552543 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 1,235E-03 0,015481 ! regulation of membrane potential GO:0042391 164 93 2,000 1,235E-03 0,01540079 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 1,235E-03 0,0153214 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 1,314E-03 0,01620658 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 1,343E-03 0,01648074 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,343E-03 0,01639708 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,343E-03 0,01631427 ! vesicle docking GO:0048278 47 24 1,000 1,343E-03 0,01623229 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 1,343E-03 0,01615112 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,343E-03 0,01607077 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 1,395E-03 0,01661156 ! interphase GO:0051325 213 98 2,000 1,436E-03 0,01702433 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,457E-03 0,01718628 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 1,457E-03 0,01710245 ! negative regulation of DNA replication GO:0008156 42 25 1,000 1,457E-03 0,01701943 ! response to starvation GO:0042594 42 25 1,000 1,457E-03 0,01693721 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,457E-03 0,01685578 ! negative regulation of cell development GO:0010721 73 25 1,000 1,457E-03 0,01677513 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 1,457E-03 0,01669525 ! cellular response to nutrient levels GO:0031669 41 25 1,000 1,457E-03 0,01661612 ! cell cycle arrest GO:0007050 213 100 2,000 1,522E-03 0,01727534 ! initiation of viral infection GO:0019059 57 26 1,000 1,576E-03 0,01780582 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,576E-03 0,01772262 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 1,576E-03 0,01764018 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 1,576E-03 0,01755852 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 1,576E-03 0,0174776 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 1,7E-03 0,01876188 ! protein amino acid acylation GO:0043543 55 27 1,000 1,7E-03 0,01867621 ! mitochondrial membrane organization GO:0007006 57 27 1,000 1,7E-03 0,01859131 ! response to toxin GO:0009636 47 27 1,000 1,7E-03 0,01850719 ! base-excision repair GO:0006284 41 27 1,000 1,7E-03 0,01842382 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,828E-03 0,01972332 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 1,828E-03 0,01963527 ! regulation of pH GO:0006885 43 29 1,000 1,961E-03 0,02096546 ! membrane docking GO:0022406 61 30 1,000 2,098E-03 0,02233106 ! regulation of B cell activation GO:0050864 50 30 1,000 2,098E-03 0,02223269 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 1,000 2,385E-03 0,02516582 ! response to ionizing radiation GO:0010212 65 32 1,000 2,385E-03 0,02505593 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 2,385E-03 0,02494699 ! positive regulation of catabolic process GO:0009896 64 32 1,000 2,385E-03 0,02483899 ! DNA damage checkpoint GO:0000077 71 33 1,000 2,535E-03 0,02628925 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 2,535E-03 0,02617643 ! xenobiotic metabolic process GO:0006805 51 34 1,000 2,689E-03 0,02765333 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 2,848E-03 0,02916203 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 2,848E-03 0,02903847 ! calcium-mediated signaling GO:0019722 62 35 1,000 2,848E-03 0,02891594 ! DNA integrity checkpoint GO:0031570 75 36 1,000 3,011E-03 0,03044393 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 3,179E-03 0,03200235 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 3,351E-03 0,03359063 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 3,351E-03 0,03345125 ! carbohydrate homeostasis GO:0033500 53 38 1,000 3,351E-03 0,03331302 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 3,351E-03 0,03317593 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! segmentation GO:0035282 67 39 1,000 3,527E-03 0,03477532 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 3,527E-03 0,03463338 ! T cell differentiation GO:0030217 81 41 1,000 3,891E-03 0,03805915 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 4,08E-03 0,03974252 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 4,08E-03 0,03958227 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 4,08E-03 0,03942331 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 4,273E-03 0,04112123 ! double-strand break repair GO:0006302 81 44 1,000 4,47E-03 0,04284547 ! B cell differentiation GO:0030183 107 44 1,000 4,47E-03 0,04267545 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 4,876E-03 0,04637094 ! positive regulation of protein transport GO:0051222 72 46 1,000 4,876E-03 0,04618838 ! positive regulation of DNA binding GO:0043388 73 47 1,000 5,085E-03 0,0479823 ! JNK cascade GO:0007254 91 47 1,000 5,085E-03 0,04779487 ! positive regulation of cell cycle GO:0045787 89 48 1,000 5,299E-03 0,04960679 ! mitochondrial transport GO:0006839 82 48 1,000 5,299E-03 0,04941451 ! activation of caspase activity GO:0006919 84 48 1,000 5,299E-03 0,04922372 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 5,299E-03 0,0490344 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 5,516E-03 0,05085125 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 5,516E-03 0,05065716 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 5,516E-03 0,05046455 ! histone modification GO:0016570 91 50 1,000 5,738E-03 0,05229218 ! positive regulation of binding GO:0051099 78 51 1,000 5,963E-03 0,05414256 ! viral infectious cycle GO:0019058 99 51 1,000 5,963E-03 0,05393901 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 5,963E-03 0,05373699 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! membrane fusion GO:0006944 110 52 1,000 6,193E-03 0,05559723 ! positive regulation of growth GO:0045927 90 52 1,000 6,193E-03 0,05539055 ! covalent chromatin modification GO:0016569 101 52 1,000 6,193E-03 0,0551854 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 6,426E-03 0,05705509 ! activation of phospholipase C activity GO:0007202 103 54 1,000 6,664E-03 0,05894615 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 1,000 6,905E-03 0,06085815 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 6,905E-03 0,06063604 ! aging GO:0007568 103 55 1,000 6,905E-03 0,06041555 ! heart morphogenesis GO:0003007 97 55 1,000 6,905E-03 0,06019665 ! nucleotide-excision repair GO:0006289 83 56 1,000 7,151E-03 0,06211068 ! lipid modification GO:0030258 97 57 1,000 7,4E-03 0,06404481 ! regulation of phospholipase activity GO:0010517 106 57 1,000 7,4E-03 0,06381526 ! regulation of intracellular transport GO:0032386 101 57 1,000 7,4E-03 0,06358735 ! positive regulation of lipase activity GO:0060193 108 58 1,000 7,653E-03 0,06552892 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 8,171E-03 0,06971594 ! fatty acid biosynthetic process GO:0006633 124 66 1,000 9,817E-03 0,0834595 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01010414 0,08560061 ! lung development GO:0030324 144 67 1,000 0,01010414 0,08530025 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01010414 0,085002 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01039528 0,08714649 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,01069011 0,08930696 ! respiratory tube development GO:0030323 150 70 1,000 0,01098862 0,09148311 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01123918 0,09324647 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01123918 0,09292603 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01123918 0,09260779 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01123918 0,09229173 ! neuron fate determination GO:0048664 7 5 0,000 0,01123918 0,09197781 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01123918 0,09166602 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01123918 0,09135634 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01123918 0,09104874 ! polyol transport GO:0015791 12 5 0,000 0,01123918 0,09074321 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01123918 0,09043972 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01123918 0,09013825 ! response to superoxide GO:0000303 10 5 0,000 0,01123918 0,08983879 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01123918 0,08954131 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01123918 0,0892458 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01123918 0,08895222 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01123918 0,08866058 ! female meiosis GO:0007143 7 5 0,000 0,01123918 0,08837084 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01123918 0,08808298 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01123918 0,087797 ! cobalt ion transport GO:0006824 11 5 0,000 0,01123918 0,08751287 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01123918 0,08723057 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01123918 0,08695008 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01123918 0,0866714 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01123918 0,08639449 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01123918 0,08611935 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01123918 0,08584596 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01123918 0,08557429 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01123918 0,08530434 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01123918 0,08503609 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01123918 0,08476952 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01123918 0,08450461 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01123918 0,08424136 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01123918 0,08397974 ! negative chemotaxis GO:0050919 14 5 0,000 0,01123918 0,08371974 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01123918 0,08346135 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01123918 0,08320454 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01123918 0,08294931 ! behavioral response to pain GO:0048266 9 5 0,000 0,01123918 0,08269565 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01123918 0,08244352 ! Notch receptor processing GO:0007220 8 5 0,000 0,01123918 0,08219294 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01123918 0,08194387 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01123918 0,0816963 ! micturition GO:0060073 9 5 0,000 0,01123918 0,08145023 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01123918 0,08120563 ! copulation GO:0007620 9 5 0,000 0,01123918 0,0809625 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01123918 0,08072082 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01123918 0,08048058 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01123918 0,08024177 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01123918 0,08000437 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01123918 0,07976837 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01123918 0,07953375 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01123918 0,07930052 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01123918 0,07906864 ! grooming behavior GO:0007625 6 5 0,000 0,01123918 0,07883812 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01123918 0,07860894 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01123918 0,07838109 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01123918 0,07815455 ! response to protozoan GO:0001562 10 5 0,000 0,01123918 0,07792933 ! lymph vessel development GO:0001945 10 5 0,000 0,01123918 0,07770539 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01123918 0,07748274 ! endochondral ossification GO:0001958 16 5 0,000 0,01123918 0,07726136 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01123918 0,07704124 ! parathyroid gland development GO:0060017 13 5 0,000 0,01123918 0,07682237 ! anagen GO:0042640 6 5 0,000 0,01123918 0,07660475 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01123918 0,07638835 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01123918 0,07617317 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01123918 0,0759592 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01123918 0,07574643 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01123918 0,07553485 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01123918 0,07532445 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01123918 0,07511521 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01123918 0,07490714 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01123918 0,07470021 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01123918 0,07449442 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01123918 0,07428977 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01123918 0,07408624 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01123918 0,07388381 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01123918 0,0736825 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01123918 0,07348227 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01123918 0,07328313 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01123918 0,07308507 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01123918 0,07288808 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01123918 0,07269214 ! histidine catabolic process GO:0006548 6 5 0,000 0,01123918 0,07249725 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01123918 0,07230341 ! valine metabolic process GO:0006573 10 5 0,000 0,01123918 0,0721106 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01123918 0,07191882 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01123918 0,07172805 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01123918 0,0715383 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01123918 0,07134954 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01123918 0,07116178 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01123918 0,070975 ! polyol catabolic process GO:0046174 7 5 0,000 0,01123918 0,0707892 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01123918 0,07060438 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01123918 0,07042051 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01123918 0,0702376 ! muscle cell migration GO:0014812 8 5 0,000 0,01123918 0,07005564 ! mitochondrial fission GO:0000266 8 5 0,000 0,01123918 0,06987461 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01123918 0,06969453 ! mRNA transcription GO:0009299 9 5 0,000 0,01123918 0,06951536 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01123918 0,06933712 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01123918 0,06915978 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01123918 0,06898336 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01123918 0,06880783 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01123918 0,06863319 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01123918 0,06845943 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01123918 0,06828656 ! response to food GO:0032094 6 5 0,000 0,01123918 0,06811455 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01123918 0,06794341 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01123918 0,06777312 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01123918 0,06760369 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01123918 0,0674351 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01123918 0,06726735 ! forebrain neuron development GO:0021884 13 5 0,000 0,01123918 0,06710044 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01123918 0,06693435 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01123918 0,06676908 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01123918 0,06660462 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01123918 0,06644097 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01123918 0,06627813 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01123918 0,06611608 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01123918 0,06595482 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01123918 0,06579435 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01123918 0,06563465 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01123918 0,06547573 ! basic amino acid transport GO:0015802 11 5 0,000 0,01123918 0,06531757 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01123918 0,06516018 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01123918 0,06500355 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01123918 0,06484766 ! depyrimidination GO:0045008 10 5 0,000 0,01123918 0,06469253 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01123918 0,06453813 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01123918 0,06438447 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01123918 0,06423153 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01123918 0,06407933 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01123918 0,06392784 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01123918 0,06377707 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01123918 0,063627 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01123918 0,06347764 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01123918 0,06332898 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01123918 0,06318102 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01123918 0,06303374 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01123918 0,06288715 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01123918 0,06274124 ! response to arsenic GO:0046685 10 5 0,000 0,01123918 0,06259601 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01123918 0,06245145 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01123918 0,06230755 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01123918 0,06216431 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01123918 0,06202173 ! response to cadmium ion GO:0046686 7 5 0,000 0,01123918 0,06187981 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01123918 0,06173853 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01123918 0,0615979 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01123918 0,0614579 ! decidualization GO:0046697 11 5 0,000 0,01123918 0,06131854 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01123918 0,06117981 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01123918 0,06104171 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01123918 0,06090423 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01123918 0,06076736 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01123918 0,06063111 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01123918 0,06049547 ! neural tube patterning GO:0021532 7 5 0,000 0,01123918 0,06036044 ! embryonic cleavage GO:0040016 6 5 0,000 0,01123918 0,060226 ! peroxisome fission GO:0016559 5 5 0,000 0,01123918 0,06009217 ! histone demethylation GO:0016577 10 5 0,000 0,01123918 0,05995893 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01123918 0,05982627 ! mitotic recombination GO:0006312 9 5 0,000 0,01123918 0,05969421 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01123918 0,05956272 ! metaphase plate congression GO:0051310 7 5 0,000 0,01123918 0,05943182 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01123918 0,05930148 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01123918 0,05917172 ! enteric nervous system development GO:0048484 8 5 0,000 0,01123918 0,05904252 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01123918 0,05891389 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01123918 0,05878582 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01123918 0,0586583 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01123918 0,05853133 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01123918 0,05840492 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01123918 0,05827904 ! plasminogen activation GO:0031639 5 5 0,000 0,01123918 0,05815371 ! B cell homeostasis GO:0001782 13 5 0,000 0,01123918 0,05802892 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01123918 0,05790466 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01123918 0,05778093 ! metaphase GO:0051323 8 5 0,000 0,01123918 0,05765773 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01123918 0,05753506 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01123918 0,0574129 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01123918 0,05729126 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01123918 0,05717014 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01123918 0,05704953 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01123918 0,05692942 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01123918 0,05680982 ! response to redox state GO:0051775 5 5 0,000 0,01123918 0,05669073 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01123918 0,05657213 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01123918 0,05645402 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01123918 0,05633641 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01123918 0,05621928 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01123918 0,05610265 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01123918 0,05598649 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01123918 0,05587082 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01123918 0,05575562 ! striatum development GO:0021756 9 5 0,000 0,01123918 0,0556409 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01123918 0,05552664 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01123918 0,05541286 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01123918 0,05529954 ! glial cell migration GO:0008347 11 5 0,000 0,01123918 0,05518669 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01123918 0,05507429 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01123918 0,05496235 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01123918 0,05485086 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01123918 0,05473983 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01123918 0,05462924 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01123918 0,0545191 ! neuroprotection GO:0043526 6 5 0,000 0,01123918 0,05440941 ! neural plate development GO:0001840 8 5 0,000 0,01123918 0,05430015 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01123918 0,05419133 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01123918 0,05408295 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01123918 0,053975 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01123918 0,05386748 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01123918 0,05376039 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01123918 0,05365372 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01123918 0,05354748 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01123918 0,05344165 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01123918 0,05333624 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01123918 0,05323125 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01123918 0,05312667 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01123918 0,0530225 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01123918 0,05291874 ! drug metabolic process GO:0017144 6 5 0,000 0,01123918 0,05281538 ! stem cell division GO:0017145 11 5 0,000 0,01123918 0,05271243 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,01123918 0,05260988 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01123918 0,05250772 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01123918 0,05240596 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01123918 0,0523046 ! B cell activation GO:0042113 160 71 1,000 0,01129079 0,05244332 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0115966 0,05375998 ! respiratory system development GO:0060541 153 72 1,000 0,0115966 0,0536566 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01221909 0,05642829 GO:0090046|regulation of transcription regulator activity, ! cell-matrix adhesion GO:0007160 163 75 1,000 0,01253573 0,05777964 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,01253573 0,05766916 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,01285595 0,0590294 ! regulation of catabolic process GO:0009894 161 76 1,000 0,01285595 0,05891697 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01317972 0,06028593 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01347204 0,06150612 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01347204 0,06138963 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01347204 0,06127358 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01347204 0,06115797 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01347204 0,0610428 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01347204 0,06092806 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01347204 0,06081374 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01347204 0,06069986 ! sleep GO:0030431 13 6 0,000 0,01347204 0,0605864 ! response to oxygen radical GO:0000305 11 6 0,000 0,01347204 0,06047337 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01347204 0,06036076 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01347204 0,06024856 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01347204 0,06013678 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01347204 0,06002542 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01347204 0,05991446 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01347204 0,05980392 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01347204 0,05969379 ! forebrain regionalization GO:0021871 8 6 0,000 0,01347204 0,05958405 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01347204 0,05947473 ! male meiosis GO:0007140 7 6 0,000 0,01347204 0,0593658 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01347204 0,05925727 ! response to zinc ion GO:0010043 9 6 0,000 0,01347204 0,05914913 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01347204 0,05904139 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01347204 0,05893405 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01347204 0,05882709 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01347204 0,05872052 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01347204 0,05861433 ! malate metabolic process GO:0006108 11 6 0,000 0,01347204 0,05850853 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01347204 0,05840311 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01347204 0,05829807 ! protein refolding GO:0042026 15 6 0,000 0,01347204 0,0581934 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01347204 0,05808911 ! opsonization GO:0008228 8 6 0,000 0,01347204 0,0579852 ! mating behavior GO:0007617 7 6 0,000 0,01347204 0,05788165 ! neuron remodeling GO:0016322 15 6 0,000 0,01347204 0,05777848 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01347204 0,05767567 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01347204 0,05757322 ! equilibrioception GO:0050957 14 6 0,000 0,01347204 0,05747114 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01347204 0,05736943 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01347204 0,05726807 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01347204 0,05716706 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01347204 0,05706642 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01347204 0,05696613 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01347204 0,05686619 ! toxin metabolic process GO:0009404 11 6 0,000 0,01347204 0,05676659 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01347204 0,05666735 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01347204 0,05656846 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01347204 0,05646991 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01347204 0,0563717 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01347204 0,05627383 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01347204 0,0561763 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01347204 0,05607911 ! thymic T cell selection GO:0045061 12 6 0,000 0,01347204 0,05598225 ! protein lipoylation GO:0009249 10 6 0,000 0,01347204 0,05588573 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01347204 0,05578954 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01347204 0,05569369 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01347204 0,05559816 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01347204 0,05550295 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01347204 0,05540808 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01347204 0,05531352 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01347204 0,05521929 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01347204 0,05512538 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01347204 0,05503179 ! hyperosmotic response GO:0006972 9 6 0,000 0,01347204 0,05493852 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01347204 0,05484556 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01347204 0,05475291 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01347204 0,05466058 ! urea metabolic process GO:0019627 7 6 0,000 0,01347204 0,05456856 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01347204 0,05447685 ! neutrophil activation GO:0042119 8 6 0,000 0,01347204 0,05438545 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01347204 0,05429435 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01347204 0,05420355 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01347204 0,05411306 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01347204 0,05402288 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01347204 0,05393299 ! neuron apoptosis GO:0051402 9 6 0,000 0,01347204 0,0538434 ! nucleoside salvage GO:0043174 9 6 0,000 0,01347204 0,05375411 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01347204 0,05366511 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01347204 0,05357641 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01347204 0,053488 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01347204 0,05339988 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01347204 0,05331205 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01347204 0,05322451 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01347204 0,05313725 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01347204 0,05305029 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01347204 0,0529636 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01347204 0,0528772 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01347204 0,05279108 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01347204 0,05270524 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01347204 0,05261968 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01347204 0,0525344 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01347204 0,05244939 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01347204 0,05236466 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01347204 0,0522802 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01347204 0,05219602 ! neural nucleus development GO:0048857 14 6 0,000 0,01347204 0,0521121 ! response to UV-C GO:0010225 11 6 0,000 0,01347204 0,05202845 ! astrocyte development GO:0014002 15 6 0,000 0,01347204 0,05194507 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01347204 0,05186196 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01347204 0,05177911 ! interaction with symbiont GO:0051702 13 6 0,000 0,01347204 0,05169653 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01347204 0,05161421 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01347204 0,05153216 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01347204 0,05145036 ! response to copper ion GO:0046688 10 6 0,000 0,01347204 0,05136882 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01347204 0,05128754 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01347204 0,05120652 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01347204 0,05112575 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01347204 0,05104524 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01347204 0,05096498 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01347204 0,05088497 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01347204 0,05080521 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01347204 0,05072571 ! hair follicle maturation GO:0048820 7 6 0,000 0,01347204 0,05064645 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01347204 0,05056743 ! Schwann cell development GO:0014044 15 6 0,000 0,01347204 0,05048867 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01347204 0,05041015 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01347204 0,05033187 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01347204 0,05025384 ! subpallium development GO:0021544 10 6 0,000 0,01347204 0,05017605 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01347204 0,05009849 ! histone ubiquitination GO:0016574 8 6 0,000 0,01347204 0,05002118 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01347204 0,04994411 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01347204 0,04986727 ! G2 phase GO:0051319 16 6 0,000 0,01347204 0,04979067 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01347204 0,0497143 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01347204 0,04963817 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01347204 0,04956227 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01347204 0,0494866 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01347204 0,04941117 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01347204 0,04933596 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01347204 0,04926098 ! receptor internalization GO:0031623 10 6 0,000 0,01347204 0,04918623 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01347204 0,04911171 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01347204 0,04903741 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01347204 0,04896333 ! protein deubiquitination GO:0016579 14 6 0,000 0,01347204 0,04888948 ! protein destabilization GO:0031648 9 6 0,000 0,01347204 0,04881585 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01347204 0,04874244 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01347204 0,04866926 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01347204 0,04859629 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01347204 0,04852354 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01347204 0,04845101 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01347204 0,04837869 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01347204 0,0483066 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01347204 0,04823471 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01347204 0,04816304 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01347204 0,04809158 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01347204 0,04802033 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01347204 0,0479493 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01347204 0,04787847 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01347204 0,04780785 ! catecholamine transport GO:0051937 9 6 0,000 0,01347204 0,04773745 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01347204 0,04766724 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01347204 0,04759725 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01347204 0,04752746 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01347204 0,04745787 ! maternal placenta development GO:0001893 12 6 0,000 0,01347204 0,04738849 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01347204 0,04731931 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01347204 0,04725033 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01347204 0,04718155 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01347204 0,04711297 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01347204 0,04704459 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01347204 0,04697641 ! blood coagulation GO:0007596 146 78 1,000 0,01350703 0,04703025 GO:0050817|coagulation, ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01383786 0,04811255 ! protein import into nucleus GO:0006606 158 80 1,000 0,0141722 0,0492039 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01451002 0,05030419 GO:0045937|positive regulation of phosphate metabolic process, ! T cell activation GO:0042110 168 81 1,000 0,01451002 0,05023181 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,01451002 0,05015964 ! nuclear import GO:0051170 161 81 1,000 0,01451002 0,05008768 ! response to drug GO:0042493 143 82 1,000 0,01485132 0,05119236 ! hemostasis GO:0007599 158 84 1,000 0,01554426 0,05350427 ! tRNA transcription GO:0009304 14 7 0,000 0,01569993 0,05396289 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01569993 0,05388591 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01569993 0,05380915 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01569993 0,0537326 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01569993 0,05365628 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01569993 0,05358017 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01569993 0,05350428 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01569993 0,0534286 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01569993 0,05335314 ! prostate gland development GO:0030850 13 7 0,000 0,01569993 0,05327789 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01569993 0,05320285 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01569993 0,05312802 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01569993 0,0530534 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01569993 0,05297899 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01569993 0,05290479 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01569993 0,0528308 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01569993 0,05275701 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01569993 0,05268343 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01569993 0,05261006 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01569993 0,05253689 ! glycolipid transport GO:0046836 10 7 0,000 0,01569993 0,05246392 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01569993 0,05239115 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01569993 0,05231859 ! neuron adhesion GO:0007158 12 7 0,000 0,01569993 0,05224623 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01569993 0,05217406 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01569993 0,0521021 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01569993 0,05203033 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01569993 0,05195876 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01569993 0,05188739 ! mRNA stabilization GO:0048255 18 7 0,000 0,01569993 0,05181622 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01569993 0,05174523 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01569993 0,05167445 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01569993 0,05160385 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01569993 0,05153345 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01569993 0,05146324 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01569993 0,05139323 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01569993 0,0513234 ! lipoprotein transport GO:0042953 14 7 0,000 0,01569993 0,05125376 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01569993 0,05118431 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01569993 0,05111505 ! rhythmic behavior GO:0007622 15 7 0,000 0,01569993 0,05104597 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01569993 0,05097709 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01569993 0,05090838 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01569993 0,05083987 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01569993 0,05077153 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01569993 0,05070338 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01569993 0,05063542 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01569993 0,05056763 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01569993 0,05050003 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01569993 0,05043261 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01569993 0,05036536 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01569993 0,0502983 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01569993 0,05023141 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01569993 0,0501647 ! spinal cord patterning GO:0021511 13 7 0,000 0,01569993 0,05009817 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01569993 0,05003182 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01569993 0,04996564 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01569993 0,04989963 ! adrenal gland development GO:0030325 17 7 0,000 0,01569993 0,0498338 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01569993 0,04976814 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01569993 0,04970266 ! ovulation GO:0030728 9 7 0,000 0,01569993 0,04963735 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01569993 0,04957221 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01569993 0,04950724 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01569993 0,04944244 ! microtubule nucleation GO:0007020 20 7 0,000 0,01569993 0,04937781 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01569993 0,04931334 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01569993 0,04924905 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01569993 0,04918492 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01569993 0,04912096 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01569993 0,04905717 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01569993 0,04899354 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01569993 0,04893008 ! galactose metabolic process GO:0006012 13 7 0,000 0,01569993 0,04886678 ! response to dietary excess GO:0002021 8 7 0,000 0,01569993 0,04880365 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01569993 0,04874067 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01569993 0,04867786 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01569993 0,04861521 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01569993 0,04855273 ! organ growth GO:0035265 15 7 0,000 0,01569993 0,0484904 ! purine salvage GO:0043101 10 7 0,000 0,01569993 0,04842823 ! nucleoside transport GO:0015858 8 7 0,000 0,01569993 0,04836622 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01569993 0,04830438 ! parturition GO:0007567 14 7 0,000 0,01569993 0,04824268 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01569993 0,04818115 ! rRNA modification GO:0000154 14 7 0,000 0,01569993 0,04811977 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01569993 0,04805855 ! spindle checkpoint GO:0031577 15 7 0,000 0,01569993 0,04799749 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01569993 0,04793658 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01569993 0,04787582 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01569993 0,04781522 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01569993 0,04775477 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01569993 0,04769447 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01569993 0,04763433 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01569993 0,04757433 ! fibrinolysis GO:0042730 10 7 0,000 0,01569993 0,04751449 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01569993 0,0474548 ! eating behavior GO:0042755 7 7 0,000 0,01569993 0,04739526 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01569993 0,04733587 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01569993 0,04727662 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01569993 0,04721753 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01569993 0,04715858 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01569993 0,04709978 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01569993 0,04704112 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01569993 0,04698261 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01569993 0,04692425 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01569993 0,04686603 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01569993 0,04680796 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01569993 0,04675003 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01569993 0,04669224 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01569993 0,04663459 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01569993 0,04657709 ! regulation of meiosis GO:0040020 12 7 0,000 0,01569993 0,04651973 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01569993 0,04646251 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01569993 0,04640543 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01569993 0,04634849 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01569993 0,04629169 ! transcription termination GO:0006353 13 7 0,000 0,01569993 0,04623503 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01569993 0,04617851 ! anaphase GO:0051322 17 7 0,000 0,01569993 0,04612213 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01569993 0,04606588 ! axonal fasciculation GO:0007413 18 7 0,000 0,01569993 0,04600977 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01569993 0,0459538 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01569993 0,04589796 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01569993 0,04584226 ! diuresis GO:0030146 12 7 0,000 0,01569993 0,04578669 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01569993 0,04573126 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01569993 0,04567596 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01569993 0,0456208 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01569993 0,04556577 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01569993 0,04551087 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01569993 0,0454561 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01569993 0,04540147 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01569993 0,04534696 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01569993 0,04529259 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01569993 0,04523835 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01569993 0,04518424 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01569993 0,04513025 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01569993 0,0450764 ! lymph node development GO:0048535 10 7 0,000 0,01569993 0,04502267 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01569993 0,04496907 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01569993 0,0449156 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01569993 0,04486226 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01569993 0,04480904 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01569993 0,04475595 ! adult feeding behavior GO:0008343 9 7 0,000 0,01569993 0,04470298 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01569993 0,04465014 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01569993 0,04459743 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01569993 0,04454484 ! muscle adaptation GO:0043500 14 7 0,000 0,01569993 0,04449237 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01569993 0,04444003 ! retina homeostasis GO:0001895 12 7 0,000 0,01569993 0,0443878 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01569993 0,04433571 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01569993 0,04428373 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01569993 0,04423188 ! protein prenylation GO:0018342 18 7 0,000 0,01569993 0,04418014 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01569993 0,04412853 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,01589587 0,04462713 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 148 86 1,000 0,01625088 0,04557065 ! protein localization in nucleus GO:0034504 176 87 1,000 0,01660928 0,04652145 ! regulation of protein transport GO:0051223 154 87 1,000 0,01660928 0,04646735 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,01697105 0,04742433 ! cellular defense response GO:0006968 114 89 1,000 0,01733617 0,04838844 ! ossification GO:0001503 188 90 1,000 0,01770464 0,04935962 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01792286 0,04991017 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01792286 0,04985247 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01792286 0,04979491 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01792286 0,04973747 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01792286 0,04968017 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01792286 0,049623 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01792286 0,04956596 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01792286 0,04950906 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01792286 0,04945228 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01792286 0,04939564 ! meiotic prophase I GO:0007128 13 8 0,000 0,01792286 0,04933912 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01792286 0,04928273 ! oligopeptide transport GO:0006857 15 8 0,000 0,01792286 0,04922647 ! UTP metabolic process GO:0046051 8 8 0,000 0,01792286 0,04917034 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01792286 0,04911434 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01792286 0,04905846 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01792286 0,04900272 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01792286 0,04894709 ! succinate metabolic process GO:0006105 14 8 0,000 0,01792286 0,0488916 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01792286 0,04883623 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01792286 0,04878098 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01792286 0,04872586 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01792286 0,04867087 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01792286 0,048616 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01792286 0,04856125 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01792286 0,04850662 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01792286 0,04845212 ! reflex GO:0060004 16 8 0,000 0,01792286 0,04839774 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01792286 0,04834349 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01792286 0,04828935 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01792286 0,04823534 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01792286 0,04818144 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01792286 0,04812767 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01792286 0,04807401 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01792286 0,04802048 ! pigment granule organization GO:0048753 16 8 0,000 0,01792286 0,04796706 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01792286 0,04791377 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01792286 0,04786059 ! histidine metabolic process GO:0006547 16 8 0,000 0,01792286 0,04780753 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01792286 0,04775458 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01792286 0,04770176 ! glycine catabolic process GO:0006546 13 8 0,000 0,01792286 0,04764905 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01792286 0,04759646 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01792286 0,04754398 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01792286 0,04749162 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01792286 0,04743937 ! melanin metabolic process GO:0006582 15 8 0,000 0,01792286 0,04738724 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01792286 0,04733522 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01792286 0,04728332 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01792286 0,04723153 ! macrophage activation GO:0042116 12 8 0,000 0,01792286 0,04717986 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01792286 0,04712829 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01792286 0,04707684 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01792286 0,04702551 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01792286 0,04697428 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01792286 0,04692317 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01792286 0,04687216 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01792286 0,04682127 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01792286 0,04677049 ! osteoblast development GO:0002076 16 8 0,000 0,01792286 0,04671982 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01792286 0,04666925 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01792286 0,0466188 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01792286 0,04656846 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01792286 0,04651822 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01792286 0,04646809 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01792286 0,04641807 ! response to UV-B GO:0010224 16 8 0,000 0,01792286 0,04636816 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01792286 0,04631836 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01792286 0,04626866 ! intermediate filament organization GO:0045109 12 8 0,000 0,01792286 0,04621907 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01792286 0,04616958 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01792286 0,0461202 ! cellular extravasation GO:0045123 12 8 0,000 0,01792286 0,04607093 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01792286 0,04602176 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01792286 0,0459727 ! response to antibiotic GO:0046677 11 8 0,000 0,01792286 0,04592374 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01792286 0,04587488 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01792286 0,04582613 ! DNA topological change GO:0006265 12 8 0,000 0,01792286 0,04577748 ! response to tropane GO:0014073 15 8 0,000 0,01792286 0,04572894 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01792286 0,0456805 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01792286 0,04563216 ! melanosome transport GO:0032402 13 8 0,000 0,01792286 0,04558392 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01792286 0,04553579 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01792286 0,04548775 ! mast cell activation GO:0045576 14 8 0,000 0,01792286 0,04543982 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01792286 0,04539199 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01792286 0,04534426 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01792286 0,04529663 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01792286 0,0452491 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01792286 0,04520167 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01792286 0,04515433 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01792286 0,0451071 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01792286 0,04505997 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01792286 0,04501293 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01792286 0,044966 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01792286 0,04491916 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01792286 0,04487241 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01792286 0,04482577 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01792286 0,04477922 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01792286 0,04473277 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01792286 0,04468641 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01792286 0,04464015 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01792286 0,04459399 ! hormone catabolic process GO:0042447 17 8 0,000 0,01792286 0,04454792 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01792286 0,04450195 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01792286 0,04445607 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01792286 0,04441029 ! ATP catabolic process GO:0006200 11 8 0,000 0,01792286 0,0443646 ! blastocyst growth GO:0001832 19 8 0,000 0,01792286 0,044319 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01792286 0,0442735 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01792286 0,04422809 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01792286 0,04418278 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01792286 0,04413755 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01792286 0,04409242 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01792286 0,04404738 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01792286 0,04400244 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01792286 0,04395758 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01792286 0,04391282 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01792286 0,04386815 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01792286 0,04382357 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01792286 0,04377908 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01792286 0,04373467 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01792286 0,04369036 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01792286 0,04364614 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01792286 0,04360201 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01792286 0,04355797 ! bone development GO:0060348 189 91 1,000 0,01807642 0,04388685 ! axon extension GO:0048675 15 9 0,000 0,02014084 0,04884965 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02014084 0,04880046 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02014084 0,04875136 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02014084 0,04870237 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02014084 0,04865347 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02014084 0,04860467 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02014084 0,04855597 ! phosphate transport GO:0006817 19 9 0,000 0,02014084 0,04850736 ! reproductive behavior GO:0019098 19 9 0,000 0,02014084 0,04845886 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02014084 0,04841045 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02014084 0,04836213 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02014084 0,04831391 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02014084 0,04826579 ! GTP metabolic process GO:0046039 9 9 0,000 0,02014084 0,04821777 ! RNA methylation GO:0001510 15 9 0,000 0,02014084 0,04816984 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02014084 0,048122 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02014084 0,04807426 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02014084 0,04802662 ! artery development GO:0060840 24 9 0,000 0,02014084 0,04797907 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02014084 0,04793161 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02014084 0,04788425 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02014084 0,04783698 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02014084 0,0477898 ! chemosensory behavior GO:0007635 20 9 0,000 0,02014084 0,04774272 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02014084 0,04769572 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02014084 0,04764883 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02014084 0,04760202 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02014084 0,04755531 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02014084 0,04750868 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02014084 0,04746215 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02014084 0,04741571 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02014084 0,04736936 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02014084 0,0473231 ! protein targeting to ER GO:0045047 22 9 0,000 0,02014084 0,04727693 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02014084 0,04723085 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02014084 0,04718486 ! T cell selection GO:0045058 23 9 0,000 0,02014084 0,04713897 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02014084 0,04709315 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02014084 0,04704743 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02014084 0,0470018 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02014084 0,04695626 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02014084 0,0469108 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02014084 0,04686543 ! mannose metabolic process GO:0006013 13 9 0,000 0,02014084 0,04682015 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02014084 0,04677496 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02014084 0,04672985 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02014084 0,04668483 ! receptor clustering GO:0043113 18 9 0,000 0,02014084 0,0466399 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02014084 0,04659505 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02014084 0,04655029 ! ruffle organization GO:0031529 15 9 0,000 0,02014084 0,04650562 ! retinol metabolic process GO:0042572 18 9 0,000 0,02014084 0,04646103 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02014084 0,04641653 ! behavioral fear response GO:0001662 22 9 0,000 0,02014084 0,04637211 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02014084 0,04632778 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02014084 0,04628353 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02014084 0,04623937 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02014084 0,04619529 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02014084 0,04615129 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02014084 0,04610738 ! segment specification GO:0007379 13 9 0,000 0,02014084 0,04606355 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02014084 0,04601981 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02014084 0,04597614 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02014084 0,04593257 ! response to amine stimulus GO:0014075 13 9 0,000 0,02014084 0,04588907 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02014084 0,04584565 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02014084 0,04580232 ! erythrocyte development GO:0048821 15 9 0,000 0,02014084 0,04575907 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02014084 0,0457159 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02014084 0,04567281 ! renal water homeostasis GO:0003091 14 9 0,000 0,02014084 0,04562981 ! postreplication repair GO:0006301 22 9 0,000 0,02014084 0,04558688 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02014084 0,04554404 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02014084 0,04550127 ! icosanoid secretion GO:0032309 15 9 0,000 0,02014084 0,04545859 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02014084 0,04541599 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02014084 0,04537346 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02014084 0,04533102 ! regulation of cell division GO:0051302 15 9 0,000 0,02014084 0,04528865 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02014084 0,04524636 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02014084 0,04520416 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02014084 0,04516203 ! sterol catabolic process GO:0016127 11 9 0,000 0,02014084 0,04511998 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02014084 0,04507801 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02014084 0,04503611 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02014084 0,0449943 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02014084 0,04495256 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02014084 0,0449109 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02014084 0,04486931 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02014084 0,0448278 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02014084 0,04478637 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02014084 0,04474502 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02014084 0,04470374 ! purine base metabolic process GO:0006144 21 9 0,000 0,02014084 0,04466254 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02014084 0,04462141 ! pigment granule transport GO:0051904 17 9 0,000 0,02014084 0,04458036 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02014084 0,04453939 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02014084 0,04449849 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02014084 0,04445767 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02014084 0,04441692 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02014084 0,04437624 ! mitochondrion localization GO:0051646 15 9 0,000 0,02014084 0,04433564 ! regulation of protein localization GO:0032880 176 97 1,000 0,02037595 0,04481218 ! response to virus GO:0009615 160 98 1,000 0,02077052 0,04563824 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02235389 0,04907249 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02235389 0,04902776 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02235389 0,0489831 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02235389 0,04893853 ! synapsis GO:0007129 13 10 0,000 0,02235389 0,04889404 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02235389 0,04884963 ! N-glycan processing GO:0006491 20 10 0,000 0,02235389 0,04880531 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02235389 0,04876106 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02235389 0,04871689 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02235389 0,0486728 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02235389 0,0486288 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02235389 0,04858487 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02235389 0,04854102 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02235389 0,04849725 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02235389 0,04845356 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02235389 0,04840994 ! androgen metabolic process GO:0008209 17 10 0,000 0,02235389 0,04836641 ! phospholipid efflux GO:0033700 16 10 0,000 0,02235389 0,04832295 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02235389 0,04827958 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02235389 0,04823628 ! lung alveolus development GO:0048286 26 10 0,000 0,02235389 0,04819305 ! pathogenesis GO:0009405 13 10 0,000 0,02235389 0,04814991 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02235389 0,04810684 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02235389 0,04806385 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02235389 0,04802094 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02235389 0,0479781 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02235389 0,04793534 ! endoderm development GO:0007492 16 10 0,000 0,02235389 0,04789265 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02235389 0,04785004 ! arginine catabolic process GO:0006527 13 10 0,000 0,02235389 0,04780751 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02235389 0,04776505 ! proline metabolic process GO:0006560 13 10 0,000 0,02235389 0,04772267 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02235389 0,04768036 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02235389 0,04763813 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02235389 0,04759597 ! V(D)J recombination GO:0033151 28 10 0,000 0,02235389 0,04755389 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02235389 0,04751188 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02235389 0,04746994 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02235389 0,04742808 ! B cell proliferation GO:0042100 18 10 0,000 0,02235389 0,0473863 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02235389 0,04734458 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02235389 0,04730294 ! multicellular organism growth GO:0035264 18 10 0,000 0,02235389 0,04726138 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02235389 0,04721988 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02235389 0,04717846 ! epithelial cell development GO:0002064 20 10 0,000 0,02235389 0,04713711 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02235389 0,04709584 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02235389 0,04705463 ! macroautophagy GO:0016236 17 10 0,000 0,02235389 0,0470135 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02235389 0,04697244 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02235389 0,04693146 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02235389 0,04689054 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02235389 0,04684969 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02235389 0,04680892 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02235389 0,04676822 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02235389 0,04672758 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02235389 0,04668702 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02235389 0,04664653 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02235389 0,04660611 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02235389 0,04656576 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02235389 0,04652547 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02235389 0,04648526 ! response to dsRNA GO:0043331 20 10 0,000 0,02235389 0,04644512 ! DNA ligation GO:0006266 19 10 0,000 0,02235389 0,04640505 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02235389 0,04636504 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02235389 0,04632511 ! melanosome localization GO:0032400 16 10 0,000 0,02235389 0,04628524 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02235389 0,04624544 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02235389 0,04620571 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02235389 0,04616605 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02235389 0,04612646 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02235389 0,04608693 ! mRNA cleavage GO:0006379 17 10 0,000 0,02235389 0,04604747 ! protein sumoylation GO:0016925 15 10 0,000 0,02235389 0,04600808 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02235389 0,04596876 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02235389 0,0459295 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02235389 0,04589031 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02235389 0,04585119 ! salivary gland development GO:0007431 27 10 0,000 0,02235389 0,04581214 ! prophase GO:0051324 15 10 0,000 0,02235389 0,04577315 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02235389 0,04573422 ! apical protein localization GO:0045176 15 10 0,000 0,02235389 0,04569537 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02235389 0,04565658 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02235389 0,04561785 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02235389 0,04557919 ! midbrain development GO:0030901 13 10 0,000 0,02235389 0,0455406 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02235389 0,04550207 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02235389 0,04546361 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02235389 0,04542521 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02235389 0,04538688 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02235389 0,04534861 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02235389 0,0453104 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02235389 0,04527226 ! detection of calcium ion GO:0005513 23 10 0,000 0,02235389 0,04523419 ! oocyte development GO:0048599 17 10 0,000 0,02235389 0,04519617 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02235389 0,04515823 ! blastocyst formation GO:0001825 17 10 0,000 0,02235389 0,04512034 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02235389 0,04508252 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02235389 0,04504476 ! activation of innate immune response GO:0002218 12 10 0,000 0,02235389 0,04500707 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02235389 0,04496944 ! response to nicotine GO:0035094 20 10 0,000 0,02235389 0,04493187 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02235389 0,04489436 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02235389 0,04485692 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02235389 0,04481954 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02456201 0,04920582 ! respiratory burst GO:0045730 17 11 0,000 0,02456201 0,04916488 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02456201 0,04912401 ! neuron fate specification GO:0048665 17 11 0,000 0,02456201 0,04908321 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02456201 0,04904248 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02456201 0,04900182 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02456201 0,04896122 ! thyroid gland development GO:0030878 26 11 0,000 0,02456201 0,04892069 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02456201 0,04888022 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02456201 0,04883983 ! response to pain GO:0048265 24 11 0,000 0,02456201 0,0487995 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02456201 0,04875923 ! T cell proliferation GO:0042098 26 11 0,000 0,02456201 0,04871904 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02456201 0,0486789 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02456201 0,04863884 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02456201 0,04859884 ! bone resorption GO:0045453 16 11 0,000 0,02456201 0,04855891 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02456201 0,04851904 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02456201 0,04847924 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02456201 0,0484395 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02456201 0,04839983 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02456201 0,04836022 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02456201 0,04832068 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02456201 0,0482812 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02456201 0,04824179 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02456201 0,04820244 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,02456201 0,04816315 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02456201 0,04812393 ! UV protection GO:0009650 19 11 0,000 0,02456201 0,04808478 ! adult heart development GO:0007512 14 11 0,000 0,02456201 0,04804568 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02456201 0,04800665 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02456201 0,04796769 ! temperature homeostasis GO:0001659 17 11 0,000 0,02456201 0,04792878 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02456201 0,04788994 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02456201 0,04785117 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02456201 0,04781245 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02456201 0,0477738 ! regulation of organ growth GO:0046620 13 11 0,000 0,02456201 0,04773521 ! pigment granule localization GO:0051875 20 11 0,000 0,02456201 0,04769668 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02456201 0,04765822 ! vasoconstriction GO:0042310 18 11 0,000 0,02456201 0,04761981 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02456201 0,04758147 ! embryonic axis specification GO:0000578 18 11 0,000 0,02456201 0,04754319 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02456201 0,04750498 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02456201 0,04746682 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02456201 0,04742872 ! DNA methylation GO:0006306 19 11 0,000 0,02456201 0,04739069 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02456201 0,04735272 ! zymogen activation GO:0031638 15 11 0,000 0,02456201 0,0473148 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02456201 0,04727695 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02456201 0,04723916 ! nucleosome positioning GO:0016584 15 11 0,000 0,02456201 0,04720143 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02456201 0,04716376 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02456201 0,04712615 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02456201 0,0470886 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02456201 0,04705111 ! acid secretion GO:0046717 18 11 0,000 0,02456201 0,04701368 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02456201 0,0469763 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02456201 0,04693899 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02456201 0,04690174 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02456201 0,04686454 ! oocyte differentiation GO:0009994 18 11 0,000 0,02456201 0,04682741 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02456201 0,04679033 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02456201 0,04675331 ! cholesterol efflux GO:0033344 19 11 0,000 0,02456201 0,04671636 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02456201 0,04667945 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02456201 0,04664261 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02456201 0,04660583 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02456201 0,0465691 ! embryonic gut development GO:0048566 15 11 0,000 0,02456201 0,04653243 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02456201 0,04649582 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02456201 0,04645927 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02456201 0,04642277 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02456201 0,04638633 ! defense response to fungus GO:0050832 13 11 0,000 0,02456201 0,04634995 ! developmental induction GO:0031128 19 11 0,000 0,02456201 0,04631363 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02456201 0,04627736 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02456201 0,04624115 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02456201 0,046205 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02456201 0,0461689 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02456201 0,04613286 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02456201 0,04609687 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02676522 0,0501926 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02676522 0,05015351 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02676522 0,05011448 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02676522 0,05007551 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02676522 0,0500366 ! cartilage condensation GO:0001502 20 12 0,000 0,02676522 0,04999776 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02676522 0,04995897 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02676522 0,04992024 ! protein complex disassembly GO:0043241 27 12 0,000 0,02676522 0,04988157 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02676522 0,04984296 ! hippocampus development GO:0021766 26 12 0,000 0,02676522 0,04980441 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02676522 0,04976593 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02676522 0,0497275 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02676522 0,04968913 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02676522 0,04965082 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02676522 0,04961256 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02676522 0,04957437 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02676522 0,04953624 ! drug transport GO:0015893 16 12 0,000 0,02676522 0,04949816 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02676522 0,04946014 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02676522 0,04942219 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02676522 0,04938429 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02676522 0,04934644 ! focal adhesion formation GO:0048041 35 12 0,000 0,02676522 0,04930866 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02676522 0,04927093 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02676522 0,04923326 ! forebrain cell migration GO:0021885 21 12 0,000 0,02676522 0,04919565 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02676522 0,0491581 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02676522 0,0491206 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02676522 0,04908316 ! fear response GO:0042596 26 12 0,000 0,02676522 0,04904578 ! monoamine transport GO:0015844 18 12 0,000 0,02676522 0,04900845 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02676522 0,04897119 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02676522 0,04893397 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02676522 0,04889682 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02676522 0,04885972 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02676522 0,04882268 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02676522 0,04878569 ! protein homotetramerization GO:0051289 21 12 0,000 0,02676522 0,04874876 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02676522 0,04871188 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02676522 0,04867506 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02676522 0,0486383 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02676522 0,04860159 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02676522 0,04856494 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02676522 0,04852834 ! cranial nerve development GO:0021545 20 12 0,000 0,02676522 0,0484918 ! fucose catabolic process GO:0019317 22 12 0,000 0,02676522 0,04845531 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02676522 0,04841888 ! histone methylation GO:0016571 26 12 0,000 0,02676522 0,0483825 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02676522 0,04834618 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02676522 0,04830991 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02676522 0,04827369 ! T cell homeostasis GO:0043029 25 12 0,000 0,02676522 0,04823753 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02676522 0,04820143 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02676522 0,04816538 ! spleen development GO:0048536 22 12 0,000 0,02676522 0,04812938 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02676522 0,04809343 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02676522 0,04805754 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02676522 0,04802171 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02676522 0,04798592 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02676522 0,04795019 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02676522 0,04791452 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02676522 0,04787889 ! response to cold GO:0009409 17 12 0,000 0,02676522 0,04784332 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02676522 0,0478078 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02676522 0,04777234 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02896352 0,05165769 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02896352 0,05161943 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02896352 0,05158122 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02896352 0,05154307 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02896352 0,05150497 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02896352 0,05146693 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02896352 0,05142895 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02896352 0,05139102 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02896352 0,05135315 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02896352 0,05131534 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02896352 0,05127758 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02896352 0,05123987 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02896352 0,05120223 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02896352 0,05116463 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02896352 0,05112709 ! methionine metabolic process GO:0006555 27 13 0,000 0,02896352 0,05108961 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02896352 0,05105218 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02896352 0,05101481 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02896352 0,05097749 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02896352 0,05094023 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02896352 0,05090302 ! exocrine system development GO:0035272 32 13 0,000 0,02896352 0,05086586 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02896352 0,05082876 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02896352 0,05079171 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02896352 0,05075472 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02896352 0,05071778 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02896352 0,05068089 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02896352 0,05064406 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02896352 0,05060728 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02896352 0,05057056 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02896352 0,05053389 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02896352 0,05049727 ! ribosome assembly GO:0042255 17 13 0,000 0,02896352 0,0504607 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02896352 0,05042419 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02896352 0,05038773 ! chromatin silencing GO:0006342 26 13 0,000 0,02896352 0,05035132 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02896352 0,05031497 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02896352 0,05027867 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02896352 0,05024242 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02896352 0,05020622 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02896352 0,05017007 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02896352 0,05013398 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02896352 0,05009794 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02896352 0,05006195 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02896352 0,05002601 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02896352 0,04999012 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02896352 0,04995429 ! embryonic placenta development GO:0001892 23 13 0,000 0,02896352 0,0499185 ! insulin secretion GO:0030073 23 13 0,000 0,02896352 0,04988277 ! actin filament polymerization GO:0030041 24 13 0,000 0,02896352 0,04984709 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02896352 0,04981146 ! acrosome reaction GO:0007340 18 13 0,000 0,02896352 0,04977588 ! rRNA transcription GO:0009303 25 14 0,000 0,03115693 0,05350719 ! lactation GO:0007595 26 14 0,000 0,03115693 0,05346903 ! reproductive cellular process GO:0048610 20 14 0,000 0,03115693 0,05343092 ! tRNA modification GO:0006400 20 14 0,000 0,03115693 0,05339286 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03115693 0,05335486 ! regulation of S phase GO:0033261 23 14 0,000 0,03115693 0,05331691 ! water transport GO:0006833 21 14 0,000 0,03115693 0,05327902 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03115693 0,05324118 ! non-recombinational repair GO:0000726 25 14 0,000 0,03115693 0,05320339 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03115693 0,05316566 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03115693 0,05312798 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03115693 0,05309035 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03115693 0,05305278 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03115693 0,05301526 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03115693 0,05297779 ! palate development GO:0060021 31 14 0,000 0,03115693 0,05294038 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03115693 0,05290302 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03115693 0,05286571 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03115693 0,05282846 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03115693 0,05279125 ! arginine metabolic process GO:0006525 17 14 0,000 0,03115693 0,0527541 ! regulation of heart rate GO:0002027 24 14 0,000 0,03115693 0,052717 ! organic alcohol transport GO:0015850 29 14 0,000 0,03115693 0,05267996 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03115693 0,05264296 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03115693 0,05260602 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03115693 0,05256913 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03115693 0,05253229 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03115693 0,0524955 ! L-amino acid transport GO:0015807 30 14 0,000 0,03115693 0,05245877 ! bone mineralization GO:0030282 17 14 0,000 0,03115693 0,05242208 ! stem cell development GO:0048864 43 14 0,000 0,03115693 0,05238545 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03115693 0,05234887 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03115693 0,05231234 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03115693 0,05227586 ! cerebellum development GO:0021549 21 14 0,000 0,03115693 0,05223943 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03115693 0,05220305 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03115693 0,05216672 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03115693 0,05213044 ! cofactor transport GO:0051181 26 14 0,000 0,03115693 0,05209422 ! NADP metabolic process GO:0006739 24 14 0,000 0,03115693 0,05205804 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03115693 0,05202191 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03115693 0,05198584 ! intestinal absorption GO:0050892 25 14 0,000 0,03115693 0,05194981 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03115693 0,05191384 ! oxygen transport GO:0015671 21 14 0,000 0,03115693 0,05187791 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03115693 0,05184203 ! male genitalia development GO:0030539 24 14 0,000 0,03115693 0,05180621 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03115693 0,05177043 ! regulation of axon extension GO:0030516 37 14 0,000 0,03115693 0,0517347 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03115693 0,05169902 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03334546 0,05529234 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03334546 0,05525426 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03334546 0,05521623 ! superoxide anion generation GO:0042554 20 15 0,000 0,03334546 0,05517826 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03334546 0,05514033 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03334546 0,05510246 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03334546 0,05506464 ! copper ion transport GO:0006825 20 15 0,000 0,03334546 0,05502687 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03334546 0,05498916 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03334546 0,0549515 ! sulfate transport GO:0008272 23 15 0,000 0,03334546 0,05491388 ! response to cAMP GO:0051591 22 15 0,000 0,03334546 0,05487632 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03334546 0,05483881 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03334546 0,05480135 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03334546 0,05476395 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03334546 0,05472659 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03334546 0,05468929 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03334546 0,05465203 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03334546 0,05461483 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03334546 0,05457768 ! pituitary gland development GO:0021983 29 15 0,000 0,03334546 0,05454057 ! vesicle coating GO:0006901 33 15 0,000 0,03334546 0,05450352 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03334546 0,05446652 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03334546 0,05442957 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03334546 0,05439267 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03334546 0,05435582 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03334546 0,05431901 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03334546 0,05428226 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03334546 0,05424556 ! histone deacetylation GO:0016575 20 15 0,000 0,03334546 0,05420891 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03334546 0,0541723 ! tissue regeneration GO:0042246 26 15 0,000 0,03334546 0,05413575 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03334546 0,05409925 ! water homeostasis GO:0030104 27 15 0,000 0,03334546 0,05406279 ! muscle maintenance GO:0046716 26 15 0,000 0,03334546 0,05402639 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03334546 0,05399003 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03334546 0,05395372 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03334546 0,05391746 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03334546 0,05388125 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03334546 0,05384509 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03334546 0,05380898 ! detection of bacterium GO:0016045 18 15 0,000 0,03334546 0,05377291 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,03334546 0,05373689 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03334546 0,05370093 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03334546 0,05366501 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03334546 0,05362913 ! peptide hormone processing GO:0016486 23 15 0,000 0,03334546 0,05359331 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03552912 0,0570648 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03552912 0,05702673 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03552912 0,05698871 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03552912 0,05695074 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03552912 0,05691283 ! bone remodeling GO:0046849 27 16 0,000 0,03552912 0,05687496 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03552912 0,05683715 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03552912 0,05679938 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03552912 0,05676166 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03552912 0,056724 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03552912 0,05668638 ! startle response GO:0001964 28 16 0,000 0,03552912 0,05664882 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03552912 0,0566113 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03552912 0,05657384 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03552912 0,05653642 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03552912 0,05649905 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03552912 0,05646174 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03552912 0,05642447 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03552912 0,05638725 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03552912 0,05635008 ! response to osmotic stress GO:0006970 25 16 0,000 0,03552912 0,05631296 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03552912 0,05627588 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03552912 0,05623886 ! fructose metabolic process GO:0006000 25 16 0,000 0,03552912 0,05620189 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03552912 0,05616496 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03552912 0,05612808 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03552912 0,05609125 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03552912 0,05605447 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03552912 0,05601774 ! axon cargo transport GO:0008088 43 16 0,000 0,03552912 0,05598105 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03552912 0,05594442 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03552912 0,05590783 ! DNA replication initiation GO:0006270 27 16 0,000 0,03552912 0,05587129 ! neuron recognition GO:0008038 35 16 0,000 0,03552912 0,05583479 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03552912 0,05579835 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03552912 0,05576195 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03552912 0,0557256 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03552912 0,05568929 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03552912 0,05565304 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03552912 0,05561683 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03552912 0,05558067 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03552912 0,05554455 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03552912 0,05550849 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03552912 0,05547246 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03552912 0,05543649 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03552912 0,05540056 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,03552912 0,05536468 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03770792 0,05872185 ! metencephalon development GO:0022037 30 17 0,000 0,03770792 0,05868387 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03770792 0,05864593 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03770792 0,05860805 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03770792 0,05857021 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03770792 0,05853242 ! endothelial cell migration GO:0043542 28 17 0,000 0,03770792 0,05849469 ! inositol metabolic process GO:0006020 28 17 0,000 0,03770792 0,058457 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03770792 0,05841935 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03770792 0,05838176 ! glial cell development GO:0021782 27 17 0,000 0,03770792 0,05834422 ! limbic system development GO:0021761 36 17 0,000 0,03770792 0,05830672 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03770792 0,05826927 ! adult walking behavior GO:0007628 33 17 0,000 0,03770792 0,05823187 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03770792 0,05819452 ! heart looping GO:0001947 30 17 0,000 0,03770792 0,05815722 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03770792 0,05811996 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03770792 0,05808275 ! myoblast differentiation GO:0045445 45 17 0,000 0,03770792 0,05804559 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03770792 0,05800848 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03770792 0,05797141 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03770792 0,05793439 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03770792 0,05789742 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03770792 0,0578605 ! glycine metabolic process GO:0006544 28 17 0,000 0,03770792 0,05782362 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03770792 0,05778679 ! NAD metabolic process GO:0019674 29 17 0,000 0,03770792 0,05775 ! membrane budding GO:0006900 37 17 0,000 0,03770792 0,05771327 ! DNA integration GO:0015074 29 17 0,000 0,03770792 0,05767658 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03770792 0,05763993 ! regulation of protein binding GO:0043393 33 17 0,000 0,03770792 0,05760334 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03770792 0,05756679 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03770792 0,05753028 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03770792 0,05749383 ! genitalia development GO:0048806 30 17 0,000 0,03770792 0,05745741 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03770792 0,05742105 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03770792 0,05738473 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03770792 0,05734846 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03770792 0,05731223 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03770792 0,05727605 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03770792 0,05723991 ! steroid catabolic process GO:0006706 31 17 0,000 0,03770792 0,05720382 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03770792 0,05716777 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03770792 0,05713177 ! gas transport GO:0015669 25 17 0,000 0,03770792 0,05709582 ! organic cation transport GO:0015695 31 17 0,000 0,03770792 0,05705991 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03770792 0,05702405 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03770792 0,05698823 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03770792 0,05695245 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03770792 0,05691672 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03770792 0,05688104 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03988187 0,06012267 ! neuron maturation GO:0042551 42 18 0,000 0,03988187 0,06008502 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03988187 0,06004742 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03988187 0,06000987 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03988187 0,05997236 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03988187 0,0599349 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03988187 0,05989749 ! memory GO:0007613 31 18 0,000 0,03988187 0,05986012 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03988187 0,0598228 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03988187 0,05978553 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03988187 0,05974831 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03988187 0,05971113 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03988187 0,05967399 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03988187 0,0596369 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03988187 0,05959986 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03988187 0,05956287 ! response to retinoic acid GO:0032526 26 18 0,000 0,03988187 0,05952592 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03988187 0,05948901 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03988187 0,05945215 ! response to fungus GO:0009620 21 18 0,000 0,03988187 0,05941534 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03988187 0,05937858 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03988187 0,05934185 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03988187 0,05930518 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03988187 0,05926855 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03988187 0,05923196 ! vitamin transport GO:0051180 27 18 0,000 0,03988187 0,05919542 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03988187 0,05915893 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03988187 0,05912248 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03988187 0,05908607 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03988187 0,05904971 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03988187 0,05901339 ! nerve development GO:0021675 28 18 0,000 0,03988187 0,05897712 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03988187 0,0589409 ! protein secretion GO:0009306 39 19 0,000 0,04205098 0,06210844 ! positive regulation of translation GO:0045727 30 19 0,000 0,04205098 0,06207034 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04205098 0,06203228 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04205098 0,06199427 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04205098 0,06195631 ! skin development GO:0043588 36 19 0,000 0,04205098 0,06191839 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04205098 0,06188052 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04205098 0,0618427 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04205098 0,06180492 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04205098 0,06176719 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04205098 0,0617295 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04205098 0,06169186 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04205098 0,06165427 ! cerebral cortex development GO:0021987 36 19 0,000 0,04205098 0,06161672 ! pigmentation during development GO:0048066 41 19 0,000 0,04205098 0,06157922 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04205098 0,06154176 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04205098 0,06150435 ! heme metabolic process GO:0042168 36 19 0,000 0,04205098 0,06146698 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04205098 0,06142966 ! neuromuscular junction development GO:0007528 34 19 0,000 0,04205098 0,06139239 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04205098 0,06135516 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04205098 0,06131797 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04205098 0,06128083 ! peptide cross-linking GO:0018149 37 19 0,000 0,04205098 0,06124374 ! protein export from nucleus GO:0006611 36 19 0,000 0,04205098 0,06120669 ! heart process GO:0003015 30 19 0,000 0,04205098 0,06116968 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04205098 0,06113272 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04205098 0,06109581 ! visual learning GO:0008542 36 19 0,000 0,04205098 0,06105894 ! cellular pigmentation GO:0033059 36 19 0,000 0,04205098 0,06102211 ! G1 phase GO:0051318 40 19 0,000 0,04205098 0,06098533 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04205098 0,06094859 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04205098 0,06091189 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04205098 0,06087524 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04205098 0,06083864 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04205098 0,06080208 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04205098 0,06076556 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04205098 0,06072909 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04205098 0,06069266 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04205098 0,06065627 ! cilium assembly GO:0042384 37 19 0,000 0,04205098 0,06061993 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04205098 0,06058363 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04421526 0,06366362 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04421526 0,06362555 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04421526 0,06358752 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04421526 0,06354953 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04421526 0,06351159 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04421526 0,0634737 ! response to vitamin GO:0033273 31 20 0,000 0,04421526 0,06343585 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04421526 0,06339804 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04421526 0,06336028 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04421526 0,06332257 ! response to alkaloid GO:0043279 38 20 0,000 0,04421526 0,0632849 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04421526 0,06324727 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04421526 0,06320969 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04421526 0,06317216 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04421526 0,06313467 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04421526 0,06309722 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04421526 0,06305982 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04421526 0,06302246 ! body fluid secretion GO:0007589 31 20 0,000 0,04421526 0,06298515 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04421526 0,06294788 ! peptide secretion GO:0002790 35 20 0,000 0,04421526 0,06291065 ! stem cell differentiation GO:0048863 53 20 0,000 0,04421526 0,06287347 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04421526 0,06283634 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04421526 0,06279924 ! sensory perception of pain GO:0019233 30 20 0,000 0,04421526 0,06276219 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04421526 0,06272519 ! diencephalon development GO:0021536 34 20 0,000 0,04421526 0,06268822 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04421526 0,06265131 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04421526 0,06261443 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04421526 0,0625776 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04421526 0,06254081 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04421526 0,06250406 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04421526 0,06246736 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04421526 0,0624307 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04421526 0,06239409 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04421526 0,06235751 ! regulation of glucose import GO:0046324 29 20 0,000 0,04421526 0,06232098 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04421526 0,06228449 ! actin filament-based movement GO:0030048 43 20 0,000 0,04421526 0,06224805 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04421526 0,06221165 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,04421526 0,06217529 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04421526 0,06213897 ! negative regulation of translation GO:0017148 29 20 0,000 0,04421526 0,06210269 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04421526 0,06206646 ! regulation of cell killing GO:0031341 42 21 0,000 0,04637472 0,06505982 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04637472 0,0650219 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04637472 0,06498403 ! hormone secretion GO:0046879 38 21 0,000 0,04637472 0,06494621 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04637472 0,06490843 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04637472 0,06487069 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04637472 0,064833 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04637472 0,06479535 ! axis specification GO:0009798 38 21 0,000 0,04637472 0,06475774 ! ovarian follicle development GO:0001541 35 21 0,000 0,04637472 0,06472018 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04637472 0,06468266 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04637472 0,06464518 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04637472 0,06460775 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04637472 0,06457036 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04637472 0,06453302 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04637472 0,06449571 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04637472 0,06445845 ! cytolysis GO:0019835 24 21 0,000 0,04637472 0,06442124 ! vasodilation GO:0042311 39 21 0,000 0,04637472 0,06438407 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04637472 0,06434693 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04637472 0,06430985 ! oogenesis GO:0048477 36 21 0,000 0,04637472 0,0642728 ! DNA modification GO:0006304 34 21 0,000 0,04637472 0,0642358 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04637472 0,06419884 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04637472 0,06416192 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04637472 0,06412505 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04637472 0,06408822 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04637472 0,06405143 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04637472 0,06401468 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04637472 0,06397797 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04637472 0,06394131 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04637472 0,06390469 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04637472 0,06386811 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04637472 0,06383157 ! collagen catabolic process GO:0030574 28 21 0,000 0,04637472 0,06379507 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04637472 0,06375862 ! gut development GO:0048565 39 21 0,000 0,04637472 0,06372221 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04852938 0,0666448 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04852938 0,06660678 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04852938 0,06656881 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04852938 0,06653088 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04852938 0,06649299 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04852938 0,06645514 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04852938 0,06641734 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04852938 0,06637958 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04852938 0,06634187 ! regeneration GO:0031099 41 22 0,000 0,04852938 0,06630419 ! keratinization GO:0031424 28 22 0,000 0,04852938 0,06626656 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04852938 0,06622898 ! sensory perception of taste GO:0050909 28 22 0,000 0,04852938 0,06619143 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04852938 0,06615393 ! vacuolar transport GO:0007034 36 22 0,000 0,04852938 0,06611647 ! lysosome organization GO:0007040 41 22 0,000 0,04852938 0,06607905 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04852938 0,06604168 ! fucose metabolic process GO:0006004 39 22 0,000 0,04852938 0,06600435 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04852938 0,06596705 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04852938 0,06592981 ! ureteric bud development GO:0001657 43 22 0,000 0,04852938 0,0658926 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04852938 0,06585544 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04852938 0,06581831 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04852938 0,06578123 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04852938 0,06574419 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04852938 0,0657072 ! sarcomere organization GO:0045214 30 22 0,000 0,04852938 0,06567024 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04852938 0,06563333 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04852938 0,06559645 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04852938 0,06555962 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04852938 0,06552283 ! protein stabilization GO:0050821 39 22 0,000 0,04852938 0,06548608 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05067924 0,06834879 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,05067924 0,0683105 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05067924 0,06827225 ! gluconeogenesis GO:0006094 33 23 0,000 0,05067924 0,06823405 ! viral genome replication GO:0019079 41 23 0,000 0,05067924 0,06819589 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05067924 0,06815777 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,05067924 0,06811969 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05067924 0,06808166 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05067924 0,06804366 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05067924 0,06800571 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05067924 0,06796781 ! visual behavior GO:0007632 42 23 0,000 0,05067924 0,06792994 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,05067924 0,06789212 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05067924 0,06785434 ! response to ethanol GO:0045471 46 23 0,000 0,05067924 0,0678166 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,05067924 0,0677789 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,05067924 0,06774125 ! peroxisome organization GO:0007031 37 23 0,000 0,05067924 0,06770364 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05067924 0,06766606 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05067924 0,06762853 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05067924 0,06759105 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05067924 0,0675536 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,05067924 0,06751619 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,05067924 0,06747883 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05067924 0,06744151 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05067924 0,06740423 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05067924 0,06736699 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,05067924 0,06732979 ! fatty acid transport GO:0015908 44 23 0,000 0,05067924 0,06729263 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,05067924 0,06725551 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05067924 0,06721844 ! hormone transport GO:0009914 40 23 0,000 0,05067924 0,0671814 ! cell-cell recognition GO:0009988 25 23 0,000 0,05067924 0,06714441 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05067924 0,06710746 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05067924 0,06707054 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,05067924 0,06703367 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,05067924 0,06699684 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05067924 0,06696005 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05282431 0,06975592 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05282431 0,06971766 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05282431 0,06967944 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05282431 0,06964126 ! spinal cord development GO:0021510 47 24 0,000 0,05282431 0,06960312 ! vacuole organization GO:0007033 43 24 0,000 0,05282431 0,06956502 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05282431 0,06952696 ! digestive system process GO:0022600 39 24 0,000 0,05282431 0,06948895 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05282431 0,06945098 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05282431 0,06941305 ! regulation of behavior GO:0050795 43 24 0,000 0,05282431 0,06937516 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05282431 0,06933731 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05282431 0,0692995 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05282431 0,06926174 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05282431 0,06922401 ! pallium development GO:0021543 49 24 0,000 0,05282431 0,06918633 ! pentose metabolic process GO:0019321 35 24 0,000 0,05282431 0,06914869 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05282431 0,06911109 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05282431 0,06907353 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05282431 0,06903601 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05282431 0,06899853 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05282431 0,06896109 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05282431 0,06892369 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05282431 0,06888634 ! regulation of amine transport GO:0051952 40 24 0,000 0,05282431 0,06884902 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05496461 0,07159981 ! myelination GO:0042552 45 25 0,000 0,05496461 0,07156106 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05496461 0,07152236 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05496461 0,0714837 ! phototransduction GO:0007602 33 25 0,000 0,05496461 0,07144508 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05496461 0,0714065 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,05496461 0,07136797 ! receptor metabolic process GO:0043112 46 25 0,000 0,05496461 0,07132947 ! chromosome condensation GO:0030261 45 25 0,000 0,05496461 0,07129102 ! osteoblast differentiation GO:0001649 60 25 0,000 0,05496461 0,07125261 ! neural crest cell development GO:0014032 54 25 0,000 0,05496461 0,07121424 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05496461 0,07117591 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05496461 0,07113763 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05496461 0,07109938 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05496461 0,07106117 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,05496461 0,07102301 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05496461 0,07098489 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,05496461 0,07094681 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05496461 0,07090876 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05496461 0,07087076 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05496461 0,0708328 ! telomere organization GO:0032200 43 25 0,000 0,05496461 0,07079488 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05496461 0,07075701 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05496461 0,07071917 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05710014 0,07342754 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05710014 0,07338832 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05710014 0,07334914 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05710014 0,07331 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05710014 0,0732709 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05710014 0,07323184 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05710014 0,07319283 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05710014 0,07315385 ! molting cycle process GO:0022404 50 26 0,000 0,05710014 0,07311492 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05710014 0,07307603 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,05710014 0,07303718 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,05710014 0,07299837 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,05710014 0,0729596 GO:0051297|centrosome organization, ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05710014 0,07292088 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,05710014 0,07288219 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05710014 0,07284355 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,05710014 0,07280495 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05710014 0,07276638 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,05710014 0,07272786 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05710014 0,07268938 ! blastocyst development GO:0001824 49 26 0,000 0,05710014 0,07265094 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05710014 0,07261254 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05710014 0,07257419 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05710014 0,07253587 ! neuron fate commitment GO:0048663 48 27 0,000 0,05923091 0,07520295 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,05923091 0,07516328 ! iron ion transport GO:0006826 59 27 0,000 0,05923091 0,07512366 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,05923091 0,07508408 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,05923091 0,07504454 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,05923091 0,07500504 ! fat cell differentiation GO:0045444 50 27 0,000 0,05923091 0,07496559 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,05923091 0,07492617 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,05923091 0,0748868 ! autophagy GO:0006914 41 27 0,000 0,05923091 0,07484747 ! male gonad development GO:0008584 44 27 0,000 0,05923091 0,07480818 ! primary neural tube formation GO:0014020 51 27 0,000 0,05923091 0,07476893 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,05923091 0,07472972 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,05923091 0,07469056 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,05923091 0,07465143 ! glutathione metabolic process GO:0006749 39 27 0,000 0,05923091 0,07461235 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,05923091 0,0745733 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,05923091 0,0745343 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,05923091 0,07449534 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,05923091 0,07445642 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06135695 0,07708868 ! circadian rhythm GO:0007623 50 28 0,000 0,06135695 0,07704844 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06135695 0,07700825 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,06135695 0,0769681 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,06135695 0,07692799 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06135695 0,07688792 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06135695 0,0768479 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06135695 0,07680792 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,06135695 0,07676797 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,06135695 0,07672807 ! synaptogenesis GO:0007416 42 28 0,000 0,06135695 0,07668821 ! lipid oxidation GO:0034440 43 28 0,000 0,06135695 0,0766484 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,06135695 0,07660862 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,06135695 0,07656889 ! translational initiation GO:0006413 65 29 0,000 0,06347824 0,07917504 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06347824 0,07913402 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,06347824 0,07909304 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06347824 0,0790521 ! catechol metabolic process GO:0009712 54 29 0,000 0,06347824 0,0790112 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,06347824 0,07897035 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,06347824 0,07892954 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,06347824 0,07888877 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,06347824 0,07884804 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,06347824 0,07880736 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,06347824 0,07876671 ! cell fate determination GO:0001709 60 29 0,000 0,06347824 0,07872611 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06347824 0,07868555 ! detection of light stimulus GO:0009583 38 29 0,000 0,06347824 0,07864503 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,06347824 0,07860456 ! tissue homeostasis GO:0001894 48 29 0,000 0,06347824 0,07856412 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,06559482 0,08114197 ! zinc ion transport GO:0006829 45 30 0,000 0,06559482 0,08110027 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,06559482 0,08105862 ! cell junction assembly GO:0034329 78 30 0,000 0,06559482 0,08101701 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06559482 0,08097544 ! acute-phase response GO:0006953 49 30 0,000 0,06559482 0,08093391 ! myofibril assembly GO:0030239 47 30 0,000 0,06559482 0,08089243 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06559482 0,08085099 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06559482 0,08080959 ! phospholipid transport GO:0015914 51 30 0,000 0,06559482 0,08076824 ! ensheathment of neurons GO:0007272 57 30 0,000 0,06559482 0,08072692 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06559482 0,08068565 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,06559482 0,08064442 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,06559482 0,08060323 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06559482 0,08056209 ! eye morphogenesis GO:0048592 60 30 0,000 0,06559482 0,08052099 ! response to heat GO:0009408 50 30 0,000 0,06559482 0,08047993 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06770668 0,08302868 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06770668 0,08298638 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06770668 0,08294413 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06770668 0,08290192 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06770668 0,08285975 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06770668 0,08281763 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06770668 0,08277554 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,06770668 0,0827335 ! ovulation cycle process GO:0022602 49 31 0,000 0,06770668 0,08269151 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06770668 0,08264955 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,06770668 0,08260764 ! peptide transport GO:0015833 55 31 0,000 0,06770668 0,08256577 ! iron ion homeostasis GO:0055072 54 31 0,000 0,06770668 0,08252395 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,06770668 0,08248216 ! mesoderm formation GO:0001707 69 31 0,000 0,06770668 0,08244042 ! natural killer cell activation GO:0030101 45 31 0,000 0,06770668 0,08239872 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06770668 0,08235706 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06770668 0,08231545 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06770668 0,08227387 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06770668 0,08223234 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06770668 0,08219085 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06981384 0,08470605 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,06981384 0,08466335 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,06981384 0,0846207 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06981384 0,08457809 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06981384 0,08453553 ! spliceosome assembly GO:0000245 67 32 0,000 0,06981384 0,084493 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,06981384 0,08445052 ! metanephros development GO:0001656 74 32 0,000 0,06981384 0,08440809 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,06981384 0,08436569 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,06981384 0,08432334 ! muscle cell development GO:0055001 49 32 0,000 0,06981384 0,08428103 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06981384 0,08423876 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,06981384 0,08419654 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06981384 0,08415435 ! ovulation cycle GO:0042698 51 32 0,000 0,06981384 0,08411221 ! peripheral nervous system development GO:0007422 64 32 0,000 0,06981384 0,08407012 ! BMP signaling pathway GO:0030509 64 32 0,000 0,06981384 0,08402806 ! hindbrain development GO:0030902 61 32 0,000 0,06981384 0,08398605 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,06981384 0,08394407 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06981384 0,08390214 ! gene silencing GO:0016458 65 32 0,000 0,06981384 0,08386026 ! post-embryonic development GO:0009791 69 33 0,000 0,0719163 0,08634263 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0719163 0,08629956 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0719163 0,08625654 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0719163 0,08621356 ! formation of primary germ layer GO:0001704 72 33 0,000 0,0719163 0,08617063 ! cell fate specification GO:0001708 52 33 0,000 0,0719163 0,08612774 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,0719163 0,08608489 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0719163 0,08604208 ! adult locomotory behavior GO:0008344 59 33 0,000 0,0719163 0,08599932 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,0719163 0,08595659 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,0719163 0,08591391 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,07401408 0,08837612 ! glial cell differentiation GO:0010001 63 34 0,000 0,07401408 0,08833229 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07401408 0,08828849 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07401408 0,08824474 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,07401408 0,08820103 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,07401408 0,08815737 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,07401408 0,08811375 ! mismatch repair GO:0006298 46 34 0,000 0,07401408 0,08807017 ! spermatid development GO:0007286 63 34 0,000 0,07401408 0,08802664 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,07401408 0,08798315 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07401408 0,0879397 ! placenta development GO:0001890 53 34 0,000 0,07401408 0,08789629 ! regulation of muscle development GO:0048634 70 35 0,000 0,07610719 0,0903374 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,07610719 0,09029286 ! negative regulation of secretion GO:0051048 63 35 0,000 0,07610719 0,09024835 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,07610719 0,0902039 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,07610719 0,09015948 ! odontogenesis GO:0042476 66 35 0,000 0,07610719 0,09011511 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,07610719 0,09007079 ! female gonad development GO:0008585 58 35 0,000 0,07610719 0,0900265 ! telencephalon development GO:0021537 68 35 0,000 0,07610719 0,08998227 ! cytokine production GO:0001816 59 35 0,000 0,07610719 0,08993807 ! neural tube formation GO:0001841 67 35 0,000 0,07610719 0,08989392 ! vesicle localization GO:0051648 64 35 0,000 0,07610719 0,08984981 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,07819564 0,09227009 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,07819564 0,09222486 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,07819564 0,09217968 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,07819564 0,09213453 ! cell junction organization GO:0034330 86 36 0,000 0,07819564 0,09208944 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,07819564 0,09204438 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,07819564 0,09199937 ! positive regulation of cell development GO:0010720 80 36 0,000 0,07819564 0,09195441 ! regulation of proteolysis GO:0030162 72 36 0,000 0,07819564 0,09190949 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,07819564 0,09186461 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,07819564 0,09181977 ! aerobic respiration GO:0009060 55 36 0,000 0,07819564 0,09177498 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,07819564 0,09173024 ! embryonic organ development GO:0048568 57 36 0,000 0,07819564 0,09168554 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,07819564 0,09164088 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,07819564 0,09159626 ! RNA export from nucleus GO:0006405 56 37 0,000 0,08027944 0,0939914 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,08027944 0,09394569 ! meiosis I GO:0007127 65 37 0,000 0,08027944 0,09390002 ! sister chromatid segregation GO:0000819 58 37 0,000 0,08027944 0,09385439 ! actomyosin structure organization GO:0031032 62 37 0,000 0,08027944 0,09380881 ! organic anion transport GO:0015711 68 37 0,000 0,08027944 0,09376327 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,08027944 0,09371777 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,08027944 0,09367232 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,08027944 0,09362692 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,08027944 0,09358156 ! glycogen metabolic process GO:0005977 61 37 0,000 0,08027944 0,09353624 ! pigment metabolic process GO:0042440 80 37 0,000 0,08027944 0,09349096 ! spermatid differentiation GO:0048515 66 37 0,000 0,08027944 0,09344573 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,0823586 0,09581953 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,0823586 0,09577321 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,0823586 0,09572695 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,0823586 0,09568073 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,0823586 0,09563455 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,0823586 0,09558841 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,0823586 0,09554232 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,0823586 0,09549628 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,0823586 0,09545028 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,0823586 0,09540432 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,0823586 0,09535841 ! glucan metabolic process GO:0044042 62 38 0,000 0,0823586 0,09531255 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,08443312 0,09766639 ! learning GO:0007612 77 39 0,000 0,08443312 0,09761946 ! ear morphogenesis GO:0042471 60 39 0,000 0,08443312 0,09757257 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,08443312 0,09752573 ! ion transmembrane transport GO:0034220 66 39 0,000 0,08443312 0,09747893 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,08443312 0,09743218 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,08443312 0,09738547 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,08443312 0,09733881 ! RNA modification GO:0009451 57 39 0,000 0,08443312 0,09729219 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,08650302 0,09962962 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,08650302 0,09958195 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08650302 0,09953433 ! feeding behavior GO:0007631 59 40 0,000 0,08650302 0,09948675 ! negative regulation of binding GO:0051100 72 40 0,000 0,08650302 0,09943921 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,08650302 0,09939173 ! mesenchymal cell development GO:0014031 87 40 0,000 0,08650302 0,09934428 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08650302 0,09929689 ! maintenance of protein location GO:0045185 91 40 0,000 0,08650302 0,09924953 ! cytokinesis GO:0000910 72 40 0,000 0,08650302 0,09920223 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08856832 0,10152233 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08856832 0,10147398 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08856832 0,10142569 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08856832 0,10137743 ! gliogenesis GO:0042063 88 41 0,000 0,08856832 0,10132923 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,08856832 0,10128107 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,08856832 0,10123295 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,08856832 0,10118488 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,08856832 0,10113686 ! female gamete generation GO:0007292 61 41 0,000 0,08856832 0,10108888 ! polyol metabolic process GO:0019751 66 41 0,000 0,08856832 0,10104095 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,08856832 0,10099307 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,09062901 0,10329388 ! regulation of tube size GO:0035150 71 42 0,000 0,09062901 0,10324498 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,09062901 0,10319611 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,09062901 0,1031473 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,09062901 0,10309853 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,09062901 0,10304981 ! neuron migration GO:0001764 79 42 0,000 0,09062901 0,10300113 ! regulation of protein secretion GO:0050708 71 42 0,000 0,09062901 0,1029525 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,09062901 0,10290391 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,09268511 0,10518885 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,09268511 0,10513926 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,09268511 0,10508971 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,09268511 0,10504021 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,09268511 0,10499076 ! glucose transport GO:0015758 65 43 0,000 0,09268511 0,10494135 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,09268511 0,10489199 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,09268511 0,10484267 ! neural tube development GO:0021915 77 43 0,000 0,09268511 0,10479341 ! striated muscle contraction GO:0006941 77 43 0,000 0,09268511 0,10474418 ! phagocytosis GO:0006909 90 43 0,000 0,09268511 0,10469501 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,09268511 0,10464588 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,09473663 0,10691197 ! hexose transport GO:0008645 67 44 0,000 0,09473663 0,10686185 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,09473663 0,10681177 ! male sex differentiation GO:0046661 76 44 0,000 0,09473663 0,10676175 ! biopolymer methylation GO:0043414 84 44 0,000 0,09473663 0,10671176 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,09473663 0,10666183 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,09473663 0,10661194 ! developmental growth GO:0048589 82 44 0,000 0,09473663 0,1065621 ! maintenance of location in cell GO:0051651 97 44 0,000 0,09473663 0,1065123 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09678358 0,10876286 ! glycolysis GO:0006096 65 45 0,000 0,09678358 0,10871209 ! leukocyte migration GO:0050900 68 45 0,000 0,09678358 0,10866136 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,09678358 0,10861067 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,09678358 0,10856004 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,09678358 0,10850945 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09678358 0,10845891 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09678358 0,10840842 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09678358 0,10835797 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09678358 0,10830758 ! cell growth GO:0016049 84 45 0,000 0,09678358 0,10825722 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,09882597 0,11049037 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,09882597 0,11043905 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,09882597 0,11038778 ! pigmentation GO:0043473 100 46 0,000 0,09882597 0,11033655 ! positive regulation of defense response GO:0031349 76 47 0,000 0,1008638 0,11255951 ! response to calcium ion GO:0051592 81 47 0,000 0,1008638 0,11250733 ! endosome transport GO:0016197 108 47 0,000 0,1008638 0,1124552 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,1008638 0,11240311 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,1008638 0,11235107 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,1008638 0,11229908 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,1008638 0,11224714 ! methylation GO:0032259 90 47 0,000 0,1008638 0,11219524 ! Notch signaling pathway GO:0007219 96 48 0,000 0,1028971 0,11440408 ! cellular component disassembly GO:0022411 86 48 0,000 0,1028971 0,11435124 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,1028971 0,11429844 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,1028971 0,1142457 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,1028971 0,114193 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,1028971 0,11414035 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,1028971 0,11408775 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,1028971 0,1140352 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,10492587 0,11623004 ! regulation of action potential GO:0001508 95 49 0,000 0,10492587 0,11617655 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,10492587 0,11612311 ! regulation of ion transport GO:0043269 77 49 0,000 0,10492587 0,11606972 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,10492587 0,11601638 ! peptide metabolic process GO:0006518 76 49 0,000 0,10492587 0,11596309 ! response to temperature stimulus GO:0009266 76 49 0,000 0,10492587 0,11590984 ! endocrine system development GO:0035270 104 49 0,000 0,10492587 0,11585665 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,10492587 0,1158035 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,10492587 0,11575041 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,10492587 0,11569736 ! neuromuscular process GO:0050905 99 50 0,000 0,10695012 0,11787539 ! regulation of ossification GO:0030278 117 50 0,000 0,10695012 0,11782142 ! inner ear development GO:0048839 79 50 0,000 0,10695012 0,1177675 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,10695012 0,11771362 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,10695012 0,1176598 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,10695012 0,11760602 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,10896985 0,11977225 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,10896985 0,11971756 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,10896985 0,11966292 ! excretion GO:0007588 83 51 0,000 0,10896985 0,11960833 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,10896985 0,11955379 ! chromatin remodeling GO:0006338 109 51 0,000 0,10896985 0,1194993 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,10896985 0,11944486 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,10896985 0,11939047 ! regulation of cell shape GO:0008360 125 51 0,000 0,10896985 0,11933612 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,10896985 0,11928183 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,11098509 0,12143252 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,11098509 0,12137733 ! amino acid activation GO:0043038 92 52 0,000 0,11098509 0,12132218 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,11098509 0,12126708 ! synapse organization GO:0050808 85 52 0,000 0,11098509 0,12121204 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,11299583 0,12335207 ! RNA catabolic process GO:0006401 93 53 0,000 0,11299583 0,12329613 ! regulation of translational initiation GO:0006446 82 53 0,000 0,11299583 0,12324024 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,11299583 0,1231844 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,11299583 0,12312861 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,11299583 0,12307287 ! cell maturation GO:0048469 100 53 0,000 0,11299583 0,12301718 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,11500209 0,12514475 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,11500209 0,12508817 ! cell recognition GO:0008037 85 54 0,000 0,11500209 0,12503165 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,11500209 0,12497517 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,11500209 0,12491875 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,11500209 0,12486238 ! chloride transport GO:0006821 90 55 0,000 0,11700388 0,1269785 ! glucose catabolic process GO:0006007 82 55 0,000 0,11700388 0,12692126 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,11700388 0,12686406 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,11700388 0,12680691 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,11700388 0,12674982 ! gastrulation GO:0007369 112 55 0,000 0,11700388 0,12669277 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,11700388 0,12663578 ! RNA elongation GO:0006354 79 55 0,000 0,11700388 0,12657884 ! nuclear export GO:0051168 97 55 0,000 0,11700388 0,12652195 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,11700388 0,12646511 ! regulation of actin filament length GO:0030832 105 56 0,000 0,11900121 0,1285662 ! sensory perception of smell GO:0007608 80 56 0,000 0,11900121 0,12850849 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,11900121 0,12845084 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,11900121 0,12839324 ! proton transport GO:0015992 94 56 0,000 0,11900121 0,12833569 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,12099409 0,13042643 ! muscle fiber development GO:0048747 112 57 0,000 0,12099409 0,13036802 ! maintenance of location GO:0051235 118 57 0,000 0,12099409 0,13030966 ! hydrogen transport GO:0006818 97 58 0,000 0,12298253 0,13239193 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,12298253 0,13233272 ! regulation of endocytosis GO:0030100 91 58 0,000 0,12298253 0,13227356 ! adult behavior GO:0030534 99 58 0,000 0,12298253 0,13221446 ! positive regulation of secretion GO:0051047 95 59 0,000 0,12496653 0,1342874 ! regulation of cellular component size GO:0032535 109 59 0,000 0,12496653 0,13422745 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,12496653 0,13416755 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,12496653 0,13410771 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,12496653 0,13404792 ! DNA catabolic process GO:0006308 86 59 0,000 0,12496653 0,13398818 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,12496653 0,1339285 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,12694612 0,13598947 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,12694612 0,13592895 ! regulation of heart contraction GO:0008016 110 60 0,000 0,12694612 0,13586848 ! camera-type eye development GO:0043010 116 60 0,000 0,12694612 0,13580807 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,12694612 0,13574771 ! kidney development GO:0001822 122 60 0,000 0,12694612 0,13568741 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,12892128 0,13773739 ! mesoderm development GO:0007498 119 61 0,000 0,12892128 0,13767626 ! tRNA processing GO:0008033 89 61 0,000 0,12892128 0,13761518 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,12892128 0,13755415 ! ear development GO:0043583 103 62 0,000 0,13089205 0,13959498 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,13089205 0,13953313 ! gonad development GO:0008406 98 62 0,000 0,13089205 0,13947134 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,13089205 0,13940959 ! regulation of mitosis GO:0007088 105 63 0,000 0,13285842 0,14144131 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,13285842 0,14137876 ! detection of external stimulus GO:0009581 91 63 0,000 0,13285842 0,14131625 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,13285842 0,14125381 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,13285842 0,14119142 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,13482041 0,14321321 ! cell redox homeostasis GO:0045454 102 64 0,000 0,13482041 0,14315001 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,13482041 0,14308686 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,13482041 0,14302377 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,13677803 0,14503655 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,13677803 0,14497266 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,13677803 0,14490882 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,13677803 0,14484504 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,13873128 0,14684886 ! actin filament organization GO:0007015 148 66 0,000 0,13873128 0,14678428 ! extracellular matrix organization GO:0030198 133 66 0,000 0,13873128 0,14671976 ! secondary metabolic process GO:0019748 116 66 0,000 0,13873128 0,1466553 ! developmental maturation GO:0021700 116 66 0,000 0,13873128 0,14659089 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,14068018 0,14858494 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,14068018 0,14851975 ! chromosome segregation GO:0007059 113 67 0,000 0,14068018 0,14845461 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,14068018 0,14838952 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,14068018 0,1483245 ! hexose catabolic process GO:0019320 104 67 0,000 0,14068018 0,14825953 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,14068018 0,14819462 ! adaptive immune response GO:0002250 119 67 0,000 0,14068018 0,14812976 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,14068018 0,14806496 ! amino acid transport GO:0006865 125 68 0,000 0,14262473 0,15004595 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,14262473 0,14998037 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,14262473 0,14991485 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,14262473 0,14984938 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,14262473 0,14978398 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,14262473 0,14971863 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,14456494 0,15168916 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,14456494 0,15162304 ! urogenital system development GO:0001655 137 69 0,000 0,14456494 0,15155697 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,14456494 0,15149096 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,14456494 0,15142501 ! antigen processing and presentation GO:0019882 104 69 0,000 0,14456494 0,15135912 ! appendage morphogenesis GO:0035107 135 70 0,000 0,14650083 0,15331927 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,1484324 0,1552732 ! reproductive structure development GO:0048608 113 71 0,000 0,1484324 0,15520572 ! appendage development GO:0048736 136 71 0,000 0,1484324 0,1551383 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,1484324 0,15507093 ! regulation of immune effector process GO:0002697 137 71 0,000 0,1484324 0,15500363 ! acute inflammatory response GO:0002526 113 72 0,000 0,15035967 0,15694809 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,15035967 0,15688003 ! carbohydrate transport GO:0008643 110 72 0,000 0,15035967 0,15681203 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,15035967 0,15674409 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,15035967 0,1566762 ! learning or memory GO:0007611 147 73 0,000 0,15228263 0,15861126 ! regulation of blood pressure GO:0008217 125 73 0,000 0,15228263 0,15854263 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,15228263 0,15847406 ! axon guidance GO:0007411 139 73 0,000 0,15228263 0,15840554 ! fertilization GO:0009566 90 73 0,000 0,15228263 0,15833709 ! transition metal ion transport GO:0000041 126 74 0,000 0,15420131 0,16026279 ! neurotransmitter transport GO:0006836 123 74 0,000 0,15420131 0,16019359 ! meiosis GO:0007126 121 74 0,000 0,15420131 0,16012445 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,15420131 0,16005537 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,15420131 0,15998635 ! eye development GO:0001654 143 74 0,000 0,15420131 0,1599174 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,15611571 0,161833 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,15611571 0,16176331 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,15611571 0,16169367 ! meiotic cell cycle GO:0051321 122 75 0,000 0,15611571 0,1616241 ! rhythmic process GO:0048511 128 75 0,000 0,15611571 0,16155458 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,15802584 0,16346095 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,15802584 0,16339071 ! defense response to bacterium GO:0042742 89 76 0,000 0,15802584 0,16332052 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,15802584 0,1632504 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,15993171 0,16514837 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,15993171 0,16507752 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,15993171 0,16500673 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,16183333 0,16689713 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,16183333 0,16682562 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,16183333 0,16675417 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,16373071 0,16863702 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,16373071 0,16856486 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,16373071 0,16849277 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,16373071 0,16842073 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,16373071 0,16834875 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,16562385 0,17022255 ! response to metal ion GO:0010038 140 80 0,000 0,16562385 0,17014987 ! muscle cell differentiation GO:0042692 159 80 0,000 0,16562385 0,17007725 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,16562385 0,17000469 ! inorganic anion transport GO:0015698 138 80 0,000 0,16562385 0,16993219 ! digestion GO:0007586 112 81 0,000 0,16751278 0,17179699 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,16751278 0,17172379 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,16751278 0,17165066 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,16939749 0,17350803 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,16939749 0,17343419 ! response to nutrient GO:0007584 125 82 0,000 0,16939749 0,17336042 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,16939749 0,17328672 ! regulation of lyase activity GO:0051339 160 83 0,000 0,17127799 0,17513593 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,1731543 0,17697929 ! negative regulation of transport GO:0051051 153 84 0,000 0,1731543 0,17690414 ! regulation of ligase activity GO:0051340 142 84 0,000 0,1731543 0,17682905 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,1731543 0,17675403 ! response to unfolded protein GO:0006986 131 85 0,000 0,17502643 0,17858931 ! nucleosome assembly GO:0006334 122 85 0,000 0,17502643 0,1785136 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,17502643 0,17843796 ! amine biosynthetic process GO:0009309 138 86 0,000 0,17689437 0,18026593 ! response to inorganic substance GO:0010035 153 86 0,000 0,17689437 0,18018961 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,17689437 0,18011336 ! chromatin assembly GO:0031497 124 86 0,000 0,17689437 0,18003717 ! tube morphogenesis GO:0035239 176 86 0,000 0,17689437 0,17996104 ! alcohol catabolic process GO:0046164 130 86 0,000 0,17689437 0,17988498 ! amine transport GO:0015837 155 86 0,000 0,17689437 0,17980898 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,17875815 0,18162674 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,17875815 0,18155007 ! cellular respiration GO:0045333 135 88 0,000 0,18061778 0,18336134 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,18061778 0,183284 ! regulation of neurological system process GO:0031644 148 88 0,000 0,18061778 0,18320673 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,18061778 0,18312953 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,18247325 0,18493287 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,18247325 0,18485501 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,18432458 0,18665191 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,18432458 0,18657339 ! sex differentiation GO:0007548 145 90 0,000 0,18432458 0,18649493 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,18432458 0,18641654 ! sterol metabolic process GO:0016125 152 91 0,000 0,18617178 0,18820559 ! response to protein stimulus GO:0051789 149 91 0,000 0,18617178 0,18812655 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,18617178 0,18804757 ! regulation of defense response GO:0031347 149 92 0,000 0,18801486 0,18982953 ! nucleosome organization GO:0034728 138 92 0,000 0,18801486 0,1897499 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,18801486 0,18967034 ! vitamin metabolic process GO:0006766 139 92 0,000 0,18801486 0,18959085 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,18985383 0,19136503 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,18985383 0,19128489 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,18985383 0,19120482 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,19168869 0,19297197 ! female pregnancy GO:0007565 164 94 0,000 0,19168869 0,19289126 ! transcription initiation GO:0006352 153 94 0,000 0,19168869 0,19281062 ! regulation of T cell activation GO:0050863 158 94 0,000 0,19168869 0,19273005 ! forebrain development GO:0030900 188 95 0,000 0,19351946 0,19448949 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,19351946 0,19440828 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,19534615 0,19616145 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,19534615 0,19607961 ! positive regulation of immune response GO:0050778 156 96 0,000 0,19534615 0,19599784 ! detection of stimulus GO:0051606 151 96 0,000 0,19534615 0,19591614 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,19716875 0,19766167 ! protein ubiquitination GO:0016567 217 97 0,000 0,19716875 0,19757935 ! hormone metabolic process GO:0042445 157 97 0,000 0,19716875 0,19749709 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,19898729 0,19923571 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,19898729 0,19915284 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,20080177 0,20088526 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,20080177 0,20080177