pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1034-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 7,724E-11 1,887E-07 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 4,000 5,874E-10 7,175E-07 ! natural killer cell mediated immunity GO:0002228 19 10 3,000 3,219E-09 2,622E-06 GO:0042267|natural killer cell mediated cytotoxicity, ! leukocyte mediated cytotoxicity GO:0001909 28 12 3,000 7,565E-09 4,621E-06 ! protein oligomerization GO:0051259 149 79 5,000 1,381E-08 6,748E-06 ! cell killing GO:0001906 32 15 3,000 2,077E-08 8,455E-06 ! positive regulation of vasoconstriction GO:0045907 10 5 2,000 7,946E-08 2,773E-05 ! inactivation of MAPK activity GO:0000188 45 22 3,000 1,101E-07 3,362E-05 ! nuclear migration GO:0007097 13 6 2,000 1,587E-07 4,308E-05 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 1,587E-07 3,877E-05 GO:0031272|regulation of pseudopodium assembly, ! regulation of protein complex assembly GO:0043254 132 63 4,000 1,9E-07 4,219E-05 ! regulation of lipid metabolic process GO:0019216 132 66 4,000 2,404E-07 4,894E-05 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 2,000 2,773E-07 5,211E-05 ! positive regulation of microtubule polymerization GO:0031116 15 7 2,000 2,773E-07 4,839E-05 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 3,009E-07 4,9E-05 ! negative regulation of kinase activity GO:0033673 145 70 4,000 3,235E-07 4,939E-05 ! negative regulation of transferase activity GO:0051348 155 74 4,000 4,279E-07 6,149E-05 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 4,43E-07 6,013E-05 ! gas homeostasis GO:0033483 14 8 2,000 4,43E-07 5,697E-05 ! establishment of nucleus localization GO:0040023 18 8 2,000 4,43E-07 5,412E-05 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 2,000 4,43E-07 5,154E-05 ! regulation of microtubule polymerization GO:0031113 17 8 2,000 4,43E-07 4,92E-05 ! spindle organization GO:0007051 50 32 3,000 5,33E-07 5,662E-05 ! regulation of epithelial cell differentiation GO:0030856 18 9 2,000 6,636E-07 6,755E-05 ! macrophage differentiation GO:0030225 15 9 2,000 6,636E-07 6,485E-05 ! negative regulation of MAP kinase activity GO:0043407 78 34 3,000 6,853E-07 6,439E-05 ! regulation of peptidase activity GO:0052547 150 82 4,000 7,157E-07 6,476E-05 ! negative regulation of MAPKKK cascade GO:0043409 20 10 2,000 9,466E-07 8,259E-05 ! nucleus localization GO:0051647 22 11 2,000 1,3E-06 1,095E-04 ! regulation of cell projection assembly GO:0060491 33 12 2,000 1,73E-06 1,409E-04 ! gland morphogenesis GO:0022612 31 13 2,000 2,246E-06 1,77E-04 ! lipid localization GO:0010876 32 14 2,000 2,855E-06 2,179E-04 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 27 14 2,000 2,855E-06 2,113E-04 ! protein homooligomerization GO:0051260 84 49 3,000 3,06E-06 2,199E-04 ! regulation of vasodilation GO:0042312 27 15 2,000 3,563E-06 2,487E-04 ! response to UV GO:0009411 120 55 3,000 4,881E-06 3,312E-04 ! filopodium assembly GO:0046847 42 17 2,000 5,31E-06 3,506E-04 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 2,000 5,31E-06 3,414E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 5,635E-06 3,53E-04 ! positive regulation of protein complex assembly GO:0031334 34 18 2,000 6,363E-06 3,886E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 6,363E-06 3,791E-04 ! microspike assembly GO:0030035 46 18 2,000 6,363E-06 3,701E-04 ! regulation of fatty acid metabolic process GO:0019217 45 20 2,000 8,863E-06 5,035E-04 ! lymphocyte mediated immunity GO:0002449 122 65 3,000 9,542E-06 5,298E-04 ! regulation of vasoconstriction GO:0019229 40 21 2,000 1,033E-05 5,605E-04 ! negative regulation of cell growth GO:0030308 142 67 3,000 1,077E-05 5,719E-04 ! cell projection assembly GO:0030031 138 68 3,000 1,142E-05 5,939E-04 ! negative regulation of cell size GO:0045792 144 69 3,000 1,211E-05 6,163E-04 ! positive regulation of cytoskeleton organization GO:0051495 52 24 2,000 1,564E-05 7,8E-04 ! membrane depolarization GO:0051899 45 24 2,000 1,564E-05 7,644E-04 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 2,000 1,564E-05 7,494E-04 ! leukocyte mediated immunity GO:0002443 136 75 3,000 1,687E-05 7,926E-04 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 1,775E-05 8,183E-04 ! vasculogenesis GO:0001570 49 25 2,000 1,775E-05 8,031E-04 ! interaction with host GO:0051701 66 25 2,000 1,775E-05 7,885E-04 ! protein tetramerization GO:0051262 57 25 2,000 1,775E-05 7,744E-04 ! regulation of smooth muscle contraction GO:0006940 48 26 2,000 2,004E-05 8,588E-04 ! regulation of cellular ketone metabolic process GO:0010565 51 26 2,000 2,004E-05 8,44E-04 ! regulation of blood coagulation GO:0030193 46 26 2,000 2,004E-05 8,297E-04 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 2,251E-05 9,165E-04 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 2,251E-05 9,015E-04 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 2,251E-05 8,87E-04 ! response to hypoxia GO:0001666 178 81 3,000 2,288E-05 8,873E-04 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 2,517E-05 9,61E-04 ! response to oxygen levels GO:0070482 183 83 3,000 2,52E-05 9,47E-04 ! negative regulation of growth GO:0045926 168 85 3,000 2,768E-05 1,024E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 3,111E-05 1,134E-03 ! negative regulation of protein kinase cascade GO:0010741 72 30 2,000 3,111E-05 1,118E-03 ! regulation of coagulation GO:0050818 52 30 2,000 3,111E-05 1,101E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 3,439E-05 1,2E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 2,000 3,439E-05 1,183E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 4,03E-05 1,368E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 4,03E-05 1,349E-03 ! microvillus organization GO:0032528 8 5 1,000 4,03E-05 1,331E-03 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 4,03E-05 1,313E-03 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 1,000 4,03E-05 1,296E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 4,03E-05 1,279E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 4,03E-05 1,262E-03 ! cholesterol homeostasis GO:0042632 60 33 2,000 4,162E-05 1,287E-03 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 2,000 4,162E-05 1,271E-03 ! cholesterol transport GO:0030301 62 34 2,000 4,559E-05 1,375E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 4,559E-05 1,358E-03 ! leukocyte differentiation GO:0002521 232 98 3,000 4,841E-05 1,425E-03 ! sterol transport GO:0015918 63 35 2,000 4,979E-05 1,448E-03 ! skeletal muscle tissue development GO:0007519 223 100 3,000 5,239E-05 1,506E-03 GO:0060538|skeletal muscle organ development, ! tissue remodeling GO:0048771 78 37 2,000 5,893E-05 1,674E-03 ! regulation of microtubule-based process GO:0032886 86 37 2,000 5,893E-05 1,655E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 6,038E-05 1,676E-03 ! neutral lipid metabolic process GO:0006638 54 38 2,000 6,389E-05 1,754E-03 GO:0006639|acylglycerol metabolic process, ! cellular response to insulin stimulus GO:0032869 85 38 2,000 6,389E-05 1,734E-03 ! mammary gland development GO:0030879 93 40 2,000 7,461E-05 2,003E-03 ! lipid homeostasis GO:0055088 75 40 2,000 7,461E-05 1,981E-03 ! glycerol ether metabolic process GO:0006662 57 40 2,000 7,461E-05 1,96E-03 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 8,038E-05 2,089E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 8,442E-05 2,171E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 8,442E-05 2,148E-03 ! vesicle fusion GO:0006906 20 7 1,000 8,442E-05 2,126E-03 ! male sex determination GO:0030238 15 7 1,000 8,442E-05 2,104E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 8,442E-05 2,083E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 8,442E-05 2,062E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 8,442E-05 2,042E-03 ! organic ether metabolic process GO:0018904 59 42 2,000 8,644E-05 2,07E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 1,064E-04 2,523E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,124E-04 2,641E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,124E-04 2,615E-03 ! ER overload response GO:0006983 13 8 1,000 1,124E-04 2,591E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,124E-04 2,567E-03 ! response to tumor cell GO:0002347 16 8 1,000 1,124E-04 2,543E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 1,124E-04 2,519E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,136E-04 2,524E-03 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 1,136E-04 2,501E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 1,212E-04 2,644E-03 ! regulation of JAK-STAT cascade GO:0046425 76 48 2,000 1,291E-04 2,791E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,443E-04 3,093E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 1,443E-04 3,066E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,443E-04 3,04E-03 ! regulation of cell projection organization GO:0031344 135 51 2,000 1,548E-04 3,232E-03 ! vesicle organization GO:0016050 127 53 2,000 1,736E-04 3,594E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 1,802E-04 3,699E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,802E-04 3,668E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,802E-04 3,638E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 1,802E-04 3,608E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 1,802E-04 3,579E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,802E-04 3,55E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of muscle contraction GO:0006937 94 54 2,000 1,835E-04 3,587E-03 ! regulation of protein polymerization GO:0032271 117 55 2,000 1,938E-04 3,759E-03 ! regulation of DNA replication GO:0006275 105 56 2,000 2,045E-04 3,934E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,199E-04 4,198E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,199E-04 4,165E-03 ! regulation of intracellular pH GO:0051453 21 11 1,000 2,199E-04 4,133E-03 ! nitric oxide metabolic process GO:0046209 17 11 1,000 2,199E-04 4,102E-03 GO:0006809|nitric oxide biosynthetic process, ! regulation of embryonic development GO:0045995 35 11 1,000 2,199E-04 4,071E-03 ! positive regulation of cell migration GO:0030335 137 58 2,000 2,27E-04 4,17E-03 ! positive regulation of organelle organization GO:0010638 108 58 2,000 2,27E-04 4,139E-03 ! establishment of organelle localization GO:0051656 122 59 2,000 2,388E-04 4,322E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 2,636E-04 4,735E-03 ! virus-host interaction GO:0019048 30 12 1,000 2,636E-04 4,7E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 2,636E-04 4,666E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 2,636E-04 4,633E-03 ! entry into host cell GO:0030260 34 12 1,000 2,636E-04 4,599E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 2,636E-04 4,567E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,636E-04 4,535E-03 ! localization within membrane GO:0051668 26 12 1,000 2,636E-04 4,503E-03 ! viral reproductive process GO:0022415 132 62 2,000 2,766E-04 4,693E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 3,039E-04 5,12E-03 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 3,039E-04 5,084E-03 ! organelle fusion GO:0048284 36 13 1,000 3,111E-04 5,17E-03 ! plasma membrane organization GO:0007009 27 13 1,000 3,111E-04 5,135E-03 ! Golgi organization GO:0007030 25 13 1,000 3,111E-04 5,101E-03 ! response to X-ray GO:0010165 28 13 1,000 3,111E-04 5,067E-03 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 3,111E-04 5,033E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 3,111E-04 5E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 3,111E-04 4,967E-03 ! positive regulation of cell motion GO:0051272 157 65 2,000 3,181E-04 5,046E-03 ! myeloid cell differentiation GO:0030099 126 67 2,000 3,479E-04 5,483E-03 ! regulation of cellular pH GO:0030641 27 14 1,000 3,625E-04 5,676E-03 ! response to gamma radiation GO:0010332 30 14 1,000 3,625E-04 5,64E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 3,625E-04 5,604E-03 ! viral reproduction GO:0016032 142 68 2,000 3,634E-04 5,583E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 4,177E-04 6,378E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 4,177E-04 6,338E-03 ! G1/S transition checkpoint GO:0031575 37 15 1,000 4,177E-04 6,299E-03 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 4,177E-04 6,26E-03 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 4,299E-04 6,405E-03 ! regulation of caspase activity GO:0043281 136 74 2,000 4,66E-04 6,899E-03 ! organelle localization GO:0051640 155 74 2,000 4,66E-04 6,858E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,767E-04 6,974E-03 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 4,767E-04 6,932E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,767E-04 6,891E-03 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 5,235E-04 7,523E-03 ! signal complex assembly GO:0007172 47 17 1,000 5,396E-04 7,709E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 6,062E-04 8,611E-03 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 6,987E-04 9,867E-03 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 7,509E-04 0,01054241 ! protein amino acid acetylation GO:0006473 41 20 1,000 7,509E-04 0,01048217 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 7,509E-04 0,01042261 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 7,509E-04 0,01036373 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 7,509E-04 0,0103055 ! lipid phosphorylation GO:0046834 43 21 1,000 8,288E-04 0,01131183 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 8,288E-04 0,01124898 ! gland development GO:0048732 220 91 2,000 8,52E-04 0,01149979 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 9,075E-04 0,01218087 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 9,105E-04 0,01215509 ! cellular response to starvation GO:0009267 37 22 1,000 9,105E-04 0,01208903 ! cell aging GO:0007569 48 22 1,000 9,105E-04 0,01202369 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 9,105E-04 0,01195904 ! positive regulation of B cell activation GO:0050871 42 22 1,000 9,105E-04 0,01189509 ! regulation of membrane potential GO:0042391 179 94 2,000 9,36E-04 0,01216325 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 9,651E-04 0,01247536 ! positive regulation of DNA replication GO:0045740 44 23 1,000 9,959E-04 0,01280547 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 9,959E-04 0,01273842 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 9,959E-04 0,01267208 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 1,025E-03 0,01297577 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 1,056E-03 0,01329729 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 1,085E-03 0,01359359 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 1,085E-03 0,01352423 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 1,085E-03 0,01345558 ! sex determination GO:0007530 48 24 1,000 1,085E-03 0,01338762 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,085E-03 0,01332035 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 1,085E-03 0,01325375 ! platelet activation GO:0030168 41 24 1,000 1,085E-03 0,01318781 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 1,178E-03 0,01424494 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 1,178E-03 0,01417477 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,178E-03 0,01410529 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 1,178E-03 0,01403648 ! negative regulation of DNA replication GO:0008156 45 25 1,000 1,178E-03 0,01396834 ! initiation of viral infection GO:0019059 60 26 1,000 1,274E-03 0,01503956 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 1,274E-03 0,01496725 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 1,274E-03 0,01489564 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 1,274E-03 0,01482471 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 1,274E-03 0,01475445 ! negative regulation of cell development GO:0010721 83 26 1,000 1,274E-03 0,01468485 GO:0050768|negative regulation of neurogenesis, ! mitochondrial membrane organization GO:0007006 60 27 1,000 1,374E-03 0,01576453 ! response to starvation GO:0042594 47 27 1,000 1,374E-03 0,01569086 ! response to toxin GO:0009636 49 27 1,000 1,374E-03 0,01561788 ! cellular response to oxidative stress GO:0034599 43 27 1,000 1,374E-03 0,01554558 ! cellular response to nutrient levels GO:0031669 45 27 1,000 1,374E-03 0,01547394 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 1,478E-03 0,0165661 ! protein amino acid acylation GO:0043543 59 28 1,000 1,478E-03 0,01649045 ! vesicle docking GO:0048278 55 28 1,000 1,478E-03 0,0164155 ! base-excision repair GO:0006284 41 28 1,000 1,478E-03 0,01634122 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 1,478E-03 0,01626761 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 1,586E-03 0,01737151 ! somitogenesis GO:0001756 52 29 1,000 1,586E-03 0,01729396 ! regulation of B cell activation GO:0050864 55 30 1,000 1,697E-03 0,01842276 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 1,93E-03 0,02085858 ! positive regulation of catabolic process GO:0009896 72 32 1,000 1,93E-03 0,02076669 ! regulation of pH GO:0006885 56 33 1,000 2,051E-03 0,02198075 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 2,051E-03 0,02188476 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 1,000 2,051E-03 0,02178961 ! response to ionizing radiation GO:0010212 74 33 1,000 2,051E-03 0,02169528 ! DNA damage checkpoint GO:0000077 78 35 1,000 2,306E-03 0,02427931 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 2,306E-03 0,02417511 ! membrane docking GO:0022406 69 35 1,000 2,306E-03 0,0240718 ! calcium-mediated signaling GO:0019722 67 35 1,000 2,306E-03 0,02396936 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 2,438E-03 0,02523876 ! xenobiotic metabolic process GO:0006805 55 37 1,000 2,574E-03 0,02653369 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 2,714E-03 0,02785366 ! DNA integrity checkpoint GO:0031570 82 38 1,000 2,714E-03 0,02773712 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 2,856E-03 0,02907658 ! carbohydrate homeostasis GO:0033500 59 39 1,000 2,856E-03 0,02895593 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 2,856E-03 0,02883628 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 3,153E-03 0,03169632 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 3,306E-03 0,03310147 ! T cell differentiation GO:0030217 93 42 1,000 3,306E-03 0,03296636 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 3,306E-03 0,03283235 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 3,463E-03 0,03424975 GO:0090047|positive regulation of transcription regulator activity, ! segmentation GO:0035282 78 43 1,000 3,463E-03 0,03411165 ! response to reactive oxygen species GO:0000302 75 44 1,000 3,623E-03 0,03554604 ! double-strand break repair GO:0006302 85 44 1,000 3,623E-03 0,03540385 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 3,787E-03 0,03685477 ! B cell differentiation GO:0030183 124 45 1,000 3,787E-03 0,03670852 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 3,954E-03 0,03817553 ! positive regulation of protein transport GO:0051222 80 46 1,000 3,954E-03 0,03802523 ! positive regulation of cell cycle GO:0045787 96 48 1,000 4,298E-03 0,04117184 ! mitochondrial transport GO:0006839 94 48 1,000 4,298E-03 0,04101101 ! positive regulation of DNA binding GO:0043388 83 48 1,000 4,298E-03 0,04085143 ! JNK cascade GO:0007254 106 49 1,000 4,475E-03 0,04236938 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 4,475E-03 0,04220579 ! activation of caspase activity GO:0006919 95 50 1,000 4,655E-03 0,04373816 ! viral infectious cycle GO:0019058 104 51 1,000 4,839E-03 0,04528985 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 4,839E-03 0,04511698 ! positive regulation of binding GO:0051099 88 52 1,000 5,026E-03 0,04668231 ! unsaturated fatty acid metabolic process GO:0033559 98 52 1,000 5,026E-03 0,04650549 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 5,026E-03 0,04633 ! histone modification GO:0016570 104 52 1,000 5,026E-03 0,04615582 ! positive regulation of growth GO:0045927 96 53 1,000 5,216E-03 0,04772392 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 5,216E-03 0,04754584 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 1,000 5,216E-03 0,04736909 ! activation of phospholipase C activity GO:0007202 110 54 1,000 5,409E-03 0,04894492 GO:0010863|positive regulation of phospholipase C activity, ! membrane fusion GO:0006944 122 54 1,000 5,409E-03 0,04876431 ! covalent chromatin modification GO:0016569 115 54 1,000 5,409E-03 0,04858503 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 5,606E-03 0,05016828 ! positive regulation of caspase activity GO:0043280 108 57 1,000 6,01E-03 0,05358157 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 6,01E-03 0,05338672 ! heart morphogenesis GO:0003007 105 57 1,000 6,01E-03 0,05319329 ! nucleotide-excision repair GO:0006289 91 57 1,000 6,01E-03 0,05300126 ! regulation of intracellular transport GO:0032386 108 57 1,000 6,01E-03 0,05281061 ! aging GO:0007568 112 58 1,000 6,216E-03 0,05442967 ! positive regulation of lipase activity GO:0060193 115 58 1,000 6,216E-03 0,05423527 ! lipid modification GO:0030258 112 60 1,000 6,639E-03 0,05771678 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 7,074E-03 0,06128385 ! activation of MAPK activity GO:0000187 124 67 1,000 8,218E-03 0,07093794 ! fatty acid biosynthetic process GO:0006633 139 67 1,000 8,218E-03 0,07068816 ! regulation of lipase activity GO:0060191 137 68 1,000 8,456E-03 0,07248029 ! lung development GO:0030324 165 69 1,000 8,697E-03 0,07428616 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 8,697E-03 0,07402732 ! cell cycle checkpoint GO:0000075 145 71 1,000 9,188E-03 0,0779381 ! respiratory tube development GO:0030323 171 72 1,000 9,438E-03 0,07978368 ! B cell activation GO:0042113 179 72 1,000 9,438E-03 0,07950856 ! respiratory system development GO:0060541 175 74 1,000 9,948E-03 0,08351282 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01008791 0,08439985 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01008791 0,0841118 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01008791 0,0838257 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01008791 0,08354155 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01008791 0,08325931 ! neuron fate determination GO:0048664 7 5 0,000 0,01008791 0,08297898 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01008791 0,08270053 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01008791 0,08242394 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01008791 0,08214919 ! polyol transport GO:0015791 12 5 0,000 0,01008791 0,08187627 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01008791 0,08160516 ! response to superoxide GO:0000303 10 5 0,000 0,01008791 0,08133583 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01008791 0,08106828 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01008791 0,08080248 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01008791 0,08053842 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01008791 0,08027608 ! female meiosis GO:0007143 10 5 0,000 0,01008791 0,08001545 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01008791 0,0797565 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01008791 0,07949922 ! hypothalamus development GO:0021854 9 5 0,000 0,01008791 0,07924359 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01008791 0,07898961 ! cobalt ion transport GO:0006824 11 5 0,000 0,01008791 0,07873724 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01008791 0,07848649 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01008791 0,07823732 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01008791 0,07798974 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01008791 0,07774371 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01008791 0,07749924 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01008791 0,07725629 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01008791 0,07701487 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01008791 0,07677494 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01008791 0,07653651 ! transposition GO:0032196 9 5 0,000 0,01008791 0,07629956 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01008791 0,07606407 ! negative chemotaxis GO:0050919 16 5 0,000 0,01008791 0,07583002 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01008791 0,07559741 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01008791 0,07536623 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01008791 0,07513645 ! behavioral response to pain GO:0048266 10 5 0,000 0,01008791 0,07490808 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01008791 0,07468108 ! Notch receptor processing GO:0007220 11 5 0,000 0,01008791 0,07445546 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01008791 0,0742312 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01008791 0,07400828 ! micturition GO:0060073 9 5 0,000 0,01008791 0,0737867 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01008791 0,07356644 ! copulation GO:0007620 9 5 0,000 0,01008791 0,07334749 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01008791 0,07312984 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01008791 0,07291348 ! bioluminescence GO:0008218 9 5 0,000 0,01008791 0,0726984 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01008791 0,07248458 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01008791 0,07227202 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01008791 0,07206069 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01008791 0,0718506 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01008791 0,07164174 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01008791 0,07143408 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01008791 0,07122762 ! grooming behavior GO:0007625 6 5 0,000 0,01008791 0,07102236 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01008791 0,07081827 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01008791 0,07061535 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01008791 0,07041359 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01008791 0,07021298 ! response to protozoan GO:0001562 13 5 0,000 0,01008791 0,07001351 ! lymph vessel development GO:0001945 10 5 0,000 0,01008791 0,06981518 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01008791 0,06961796 ! endochondral ossification GO:0001958 17 5 0,000 0,01008791 0,06942185 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01008791 0,06922685 ! single strand break repair GO:0000012 8 5 0,000 0,01008791 0,06903293 ! parathyroid gland development GO:0060017 14 5 0,000 0,01008791 0,0688401 ! anagen GO:0042640 7 5 0,000 0,01008791 0,06864835 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01008791 0,06845766 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01008791 0,06826803 ! cytokine secretion GO:0050663 15 5 0,000 0,01008791 0,06807944 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01008791 0,06789189 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01008791 0,06770538 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01008791 0,06751988 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01008791 0,0673354 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01008791 0,06715193 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01008791 0,06696945 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01008791 0,06678796 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01008791 0,06660745 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01008791 0,06642792 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01008791 0,06624935 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01008791 0,06607174 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01008791 0,06589507 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01008791 0,06571935 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01008791 0,06554457 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01008791 0,06537071 ! valine metabolic process GO:0006573 12 5 0,000 0,01008791 0,06519777 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01008791 0,06502574 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01008791 0,06485462 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01008791 0,0646844 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01008791 0,06451507 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01008791 0,06434662 ! polyol catabolic process GO:0046174 9 5 0,000 0,01008791 0,06417906 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01008791 0,06401236 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01008791 0,06384652 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01008791 0,06368154 ! muscle cell migration GO:0014812 8 5 0,000 0,01008791 0,06351742 ! mitochondrial fission GO:0000266 8 5 0,000 0,01008791 0,06335413 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01008791 0,06319169 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01008791 0,06303007 ! mRNA transcription GO:0009299 10 5 0,000 0,01008791 0,06286928 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01008791 0,06270931 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01008791 0,06255015 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01008791 0,06239179 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01008791 0,06223424 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01008791 0,06207747 ! monocyte activation GO:0042117 10 5 0,000 0,01008791 0,0619215 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01008791 0,06176631 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01008791 0,06161189 ! response to food GO:0032094 6 5 0,000 0,01008791 0,06145825 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01008791 0,06130537 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01008791 0,06115324 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01008791 0,06100187 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01008791 0,06085125 ! forebrain neuron development GO:0021884 13 5 0,000 0,01008791 0,06070137 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01008791 0,06055223 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01008791 0,06040382 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01008791 0,06025613 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01008791 0,06010916 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01008791 0,05996291 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01008791 0,05981737 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01008791 0,05967254 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01008791 0,0595284 ! lipid glycosylation GO:0030259 7 5 0,000 0,01008791 0,05938496 ! nucleobase transport GO:0015851 6 5 0,000 0,01008791 0,0592422 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01008791 0,05910014 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01008791 0,05895875 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01008791 0,05881804 ! basic amino acid transport GO:0015802 12 5 0,000 0,01008791 0,05867799 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01008791 0,05853862 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01008791 0,0583999 ! actin nucleation GO:0045010 11 5 0,000 0,01008791 0,05826184 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01008791 0,05812443 ! depurination GO:0045007 5 5 0,000 0,01008791 0,05798766 ! depyrimidination GO:0045008 10 5 0,000 0,01008791 0,05785154 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01008791 0,05771606 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01008791 0,05758121 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01008791 0,05744699 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01008791 0,05731339 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01008791 0,05718041 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01008791 0,05704805 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01008791 0,0569163 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01008791 0,05678515 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01008791 0,05665461 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01008791 0,05652467 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01008791 0,05639533 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01008791 0,05626657 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01008791 0,0561384 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01008791 0,05601081 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01008791 0,0558838 ! response to arsenic GO:0046685 11 5 0,000 0,01008791 0,05575737 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01008791 0,05563151 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01008791 0,05550621 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01008791 0,05538148 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01008791 0,0552573 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01008791 0,05513368 ! response to mercury ion GO:0046689 8 5 0,000 0,01008791 0,05501062 ! response to cadmium ion GO:0046686 7 5 0,000 0,01008791 0,0548881 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01008791 0,05476613 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01008791 0,05464469 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01008791 0,0545238 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01008791 0,05440344 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01008791 0,05428361 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01008791 0,0541643 ! decidualization GO:0046697 11 5 0,000 0,01008791 0,05404552 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01008791 0,05392726 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01008791 0,05380951 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01008791 0,05369228 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01008791 0,05357556 ! embryonic cleavage GO:0040016 6 5 0,000 0,01008791 0,05345934 ! peroxisome fission GO:0016559 5 5 0,000 0,01008791 0,05334363 ! histone demethylation GO:0016577 13 5 0,000 0,01008791 0,05322842 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01008791 0,0531137 ! mitotic recombination GO:0006312 9 5 0,000 0,01008791 0,05299948 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01008791 0,05288575 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01008791 0,0527725 ! metaphase plate congression GO:0051310 7 5 0,000 0,01008791 0,05265974 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01008791 0,05254746 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01008791 0,05243565 ! enteric nervous system development GO:0048484 8 5 0,000 0,01008791 0,05232433 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01008791 0,05221347 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01008791 0,05210308 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01008791 0,05199316 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01008791 0,0518837 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01008791 0,0517747 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01008791 0,05166616 ! B cell homeostasis GO:0001782 13 5 0,000 0,01008791 0,05155807 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01008791 0,05145043 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01008791 0,05134324 ! metaphase GO:0051323 11 5 0,000 0,01008791 0,0512365 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01008791 0,0511302 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01008791 0,05102434 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01008791 0,05091892 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01008791 0,05081393 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01008791 0,05070938 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01008791 0,05060525 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01008791 0,05050155 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01008791 0,05039828 ! response to redox state GO:0051775 6 5 0,000 0,01008791 0,05029542 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01008791 0,05019299 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01008791 0,05009097 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01008791 0,04998937 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01008791 0,04988817 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01008791 0,04978739 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01008791 0,04968701 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01008791 0,04958704 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01008791 0,04948746 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01008791 0,04938829 ! striatum development GO:0021756 14 5 0,000 0,01008791 0,04928951 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01008791 0,04919113 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01008791 0,04909314 ! glial cell migration GO:0008347 10 5 0,000 0,01008791 0,04899554 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01008791 0,04889833 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01008791 0,0488015 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01008791 0,04870505 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01008791 0,04860899 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01008791 0,0485133 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01008791 0,04841799 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01008791 0,04832305 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01008791 0,04822849 ! neuroprotection GO:0043526 8 5 0,000 0,01008791 0,04813429 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01008791 0,04804046 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01008791 0,047947 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01008791 0,0478539 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01008791 0,04776116 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01008791 0,04766878 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01008791 0,04757675 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01008791 0,04748508 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01008791 0,04739376 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01008791 0,0473028 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01008791 0,04721218 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01008791 0,04712191 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01008791 0,04703198 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01008791 0,04694239 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01008791 0,04685315 ! protein palmitoylation GO:0018345 12 5 0,000 0,01008791 0,04676425 ! drug metabolic process GO:0017144 7 5 0,000 0,01008791 0,04667568 ! stem cell division GO:0017145 11 5 0,000 0,01008791 0,04658744 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,01008791 0,04649954 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01008791 0,04641197 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01008791 0,04632473 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01020696 0,0467835 GO:0090046|regulation of transcription regulator activity, ! cell-matrix adhesion GO:0007160 181 76 1,000 0,01046921 0,04789564 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,01046921 0,04780611 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01073442 0,04892574 ! regulation of catabolic process GO:0009894 173 77 1,000 0,01073442 0,04883463 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,0110026 0,04996163 ! blood coagulation GO:0007596 151 79 1,000 0,01127373 0,0510978 GO:0050817|coagulation, ! steroid biosynthetic process GO:0006694 146 79 1,000 0,01127373 0,05100317 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,01182476 0,05339722 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01209341 0,05450961 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01209341 0,05440922 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01209341 0,05430921 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01209341 0,05420956 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01209341 0,05411027 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01209341 0,05401135 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01209341 0,05391279 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01209341 0,05381459 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01209341 0,05371674 ! response to oxygen radical GO:0000305 11 6 0,000 0,01209341 0,05361925 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01209341 0,05352212 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01209341 0,05342533 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01209341 0,0533289 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01209341 0,05323281 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01209341 0,05313706 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01209341 0,05304167 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01209341 0,05294661 ! forebrain regionalization GO:0021871 9 6 0,000 0,01209341 0,05285189 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01209341 0,05275751 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01209341 0,05266347 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01209341 0,05256976 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01209341 0,05247639 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01209341 0,05238335 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01209341 0,05229063 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01209341 0,05219825 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01209341 0,05210619 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01209341 0,05201445 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01209341 0,05192304 ! malate metabolic process GO:0006108 13 6 0,000 0,01209341 0,05183194 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01209341 0,05174117 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01209341 0,05165071 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01209341 0,05156057 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01209341 0,05147075 ! protein refolding GO:0042026 15 6 0,000 0,01209341 0,05138123 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01209341 0,05129203 ! opsonization GO:0008228 8 6 0,000 0,01209341 0,05120313 ! mating behavior GO:0007617 7 6 0,000 0,01209341 0,05111455 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01209341 0,05102627 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01209341 0,05093829 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01209341 0,05085062 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01209341 0,05076324 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01209341 0,05067617 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01209341 0,0505894 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01209341 0,05050292 ! toxin metabolic process GO:0009404 11 6 0,000 0,01209341 0,05041674 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01209341 0,05033085 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01209341 0,05024525 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01209341 0,05015995 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01209341 0,05007493 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01209341 0,0499902 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01209341 0,04990576 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01209341 0,0498216 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01209341 0,04973772 ! thymic T cell selection GO:0045061 16 6 0,000 0,01209341 0,04965413 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01209341 0,04957082 ! protein lipoylation GO:0009249 10 6 0,000 0,01209341 0,04948779 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01209341 0,04940503 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01209341 0,04932255 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01209341 0,04924035 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01209341 0,04915842 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01209341 0,04907676 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01209341 0,04899537 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01209341 0,04891425 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01209341 0,0488334 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01209341 0,04875282 ! hyperosmotic response GO:0006972 10 6 0,000 0,01209341 0,0486725 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01209341 0,04859245 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01209341 0,04851266 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01209341 0,04843313 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01209341 0,04835386 ! urea metabolic process GO:0019627 7 6 0,000 0,01209341 0,04827485 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01209341 0,0481961 ! neutrophil activation GO:0042119 7 6 0,000 0,01209341 0,0481176 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01209341 0,04803936 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01209341 0,04796138 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01209341 0,04788364 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01209341 0,04780616 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01209341 0,04772893 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01209341 0,04765195 ! neuron apoptosis GO:0051402 15 6 0,000 0,01209341 0,04757521 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01209341 0,04749873 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01209341 0,04742248 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01209341 0,04734649 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01209341 0,04727073 ! carnitine transport GO:0015879 10 6 0,000 0,01209341 0,04719522 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01209341 0,04711995 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01209341 0,04704492 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01209341 0,04697012 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01209341 0,04689557 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01209341 0,04682125 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01209341 0,04674716 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01209341 0,04667331 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01209341 0,0465997 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01209341 0,04652631 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01209341 0,04645316 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01209341 0,04638023 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01209341 0,04630754 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01209341 0,04623507 ! response to UV-C GO:0010225 14 6 0,000 0,01209341 0,04616282 ! astrocyte development GO:0014002 16 6 0,000 0,01209341 0,04609081 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01209341 0,04601902 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01209341 0,04594745 ! interaction with symbiont GO:0051702 14 6 0,000 0,01209341 0,0458761 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01209341 0,04580497 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01209341 0,04573407 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01209341 0,04566338 ! response to copper ion GO:0046688 10 6 0,000 0,01209341 0,04559291 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01209341 0,04552266 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01209341 0,04545263 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01209341 0,04538281 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01209341 0,0453132 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01209341 0,04524381 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01209341 0,04517463 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01209341 0,04510566 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01209341 0,0450369 ! hair follicle maturation GO:0048820 8 6 0,000 0,01209341 0,04496835 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01209341 0,04490001 ! Schwann cell development GO:0014044 15 6 0,000 0,01209341 0,04483188 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01209341 0,04476395 ! response to pheromone GO:0019236 6 6 0,000 0,01209341 0,04469623 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01209341 0,04462871 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01209341 0,0445614 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01209341 0,04449429 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01209341 0,04442738 ! subpallium development GO:0021544 15 6 0,000 0,01209341 0,04436067 ! neural tube patterning GO:0021532 8 6 0,000 0,01209341 0,04429416 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01209341 0,04422786 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01209341 0,04416175 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01209341 0,04409583 ! G2 phase GO:0051319 16 6 0,000 0,01209341 0,04403012 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01209341 0,0439646 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01209341 0,04389927 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01209341 0,04383414 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01209341 0,0437692 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01209341 0,04370445 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01209341 0,04363989 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01209341 0,04357553 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01209341 0,04351135 ! receptor internalization GO:0031623 11 6 0,000 0,01209341 0,04344736 ! plasminogen activation GO:0031639 9 6 0,000 0,01209341 0,04338357 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01209341 0,04331995 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01209341 0,04325653 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01209341 0,04319329 ! protein deubiquitination GO:0016579 16 6 0,000 0,01209341 0,04313023 ! protein destabilization GO:0031648 9 6 0,000 0,01209341 0,04306736 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01209341 0,04300467 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01209341 0,04294216 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01209341 0,04287984 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01209341 0,04281769 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01209341 0,04275573 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01209341 0,04269394 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01209341 0,04263233 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01209341 0,0425709 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01209341 0,04250965 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01209341 0,04244857 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01209341 0,04238767 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01209341 0,04232695 ! neural plate development GO:0001840 9 6 0,000 0,01209341 0,04226639 ! catecholamine transport GO:0051937 9 6 0,000 0,01209341 0,04220601 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01209341 0,0421458 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01209341 0,04208577 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01209341 0,0420259 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01209341 0,0419662 ! maternal placenta development GO:0001893 12 6 0,000 0,01209341 0,04190668 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01209341 0,04184732 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01209341 0,04178813 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01209341 0,04172911 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01209341 0,04167025 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01209341 0,04161156 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01209341 0,04155303 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01209341 0,04149467 GO:0055081|anion homeostasis, ! cell-substrate adhesion GO:0031589 189 82 1,000 0,01210465 0,04147498 ! protein import into nucleus GO:0006606 174 82 1,000 0,01210465 0,04141689 ! response to drug GO:0042493 149 83 1,000 0,01238743 0,04232518 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,01238743 0,04226607 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,01238743 0,04220712 ! T cell activation GO:0042110 189 84 1,000 0,0126731 0,04312032 ! hemostasis GO:0007599 165 85 1,000 0,01296164 0,04404074 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,01325304 0,0449683 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 159 87 1,000 0,01354728 0,04590293 ! regulation of protein transport GO:0051223 165 87 1,000 0,01354728 0,04583935 GO:0070201|regulation of establishment of protein localization, ! tRNA transcription GO:0009304 17 7 0,000 0,01409491 0,04762638 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01409491 0,04756059 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01409491 0,04749499 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01409491 0,04742957 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01409491 0,04736433 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01409491 0,04729927 ! sleep GO:0030431 16 7 0,000 0,01409491 0,04723439 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01409491 0,04716969 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01409491 0,04710516 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01409491 0,04704081 ! prostate gland development GO:0030850 14 7 0,000 0,01409491 0,04697663 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01409491 0,04691263 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01409491 0,0468488 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01409491 0,04678515 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01409491 0,04672167 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01409491 0,04665836 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01409491 0,04659522 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01409491 0,04653226 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01409491 0,04646946 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01409491 0,04640683 ! glycolipid transport GO:0046836 11 7 0,000 0,01409491 0,04634437 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01409491 0,04628208 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01409491 0,04621996 ! neuron adhesion GO:0007158 14 7 0,000 0,01409491 0,046158 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01409491 0,04609621 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01409491 0,04603459 ! mRNA stabilization GO:0048255 18 7 0,000 0,01409491 0,04597312 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01409491 0,04591183 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01409491 0,04585069 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01409491 0,04578972 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01409491 0,04572891 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01409491 0,04566826 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01409491 0,04560777 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01409491 0,04554745 ! lipoprotein transport GO:0042953 14 7 0,000 0,01409491 0,04548728 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01409491 0,04542727 ! rhythmic behavior GO:0007622 17 7 0,000 0,01409491 0,04536742 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01409491 0,04530772 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01409491 0,04524819 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01409491 0,04518881 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01409491 0,04512958 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01409491 0,04507051 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01409491 0,04501159 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01409491 0,04495283 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01409491 0,04489422 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01409491 0,04483577 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01409491 0,04477746 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01409491 0,04471931 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01409491 0,04466131 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01409491 0,04460346 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01409491 0,04454576 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01409491 0,0444882 ! spinal cord patterning GO:0021511 14 7 0,000 0,01409491 0,0444308 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01409491 0,04437354 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01409491 0,04431644 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01409491 0,04425947 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01409491 0,04420266 ! adrenal gland development GO:0030325 17 7 0,000 0,01409491 0,04414599 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01409491 0,04408946 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01409491 0,04403308 ! ovulation GO:0030728 10 7 0,000 0,01409491 0,04397685 ! adenohypophysis development GO:0021984 11 7 0,000 0,01409491 0,04392075 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01409491 0,0438648 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01409491 0,043809 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01409491 0,04375333 ! microtubule nucleation GO:0007020 21 7 0,000 0,01409491 0,0436978 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01409491 0,04364242 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01409491 0,04358718 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01409491 0,04353207 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01409491 0,04347711 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01409491 0,04342228 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01409491 0,04336759 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01409491 0,04331304 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01409491 0,04325863 ! galactose metabolic process GO:0006012 13 7 0,000 0,01409491 0,04320435 ! response to dietary excess GO:0002021 8 7 0,000 0,01409491 0,04315021 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01409491 0,04309621 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01409491 0,04304234 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01409491 0,0429886 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01409491 0,042935 ! organ growth GO:0035265 15 7 0,000 0,01409491 0,04288153 ! nucleoside transport GO:0015858 11 7 0,000 0,01409491 0,0428282 ! nucleoside salvage GO:0043174 11 7 0,000 0,01409491 0,04277499 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01409491 0,04272192 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01409491 0,04266898 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01409491 0,04261618 ! parturition GO:0007567 16 7 0,000 0,01409491 0,0425635 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01409491 0,04251095 ! rRNA modification GO:0000154 14 7 0,000 0,01409491 0,04245853 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01409491 0,04240624 ! spindle checkpoint GO:0031577 16 7 0,000 0,01409491 0,04235408 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01409491 0,04230205 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01409491 0,04225015 ! monocyte differentiation GO:0030224 16 7 0,000 0,01409491 0,04219837 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01409491 0,04214672 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01409491 0,0420952 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01409491 0,0420438 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01409491 0,04199252 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01409491 0,04194138 ! fibrinolysis GO:0042730 11 7 0,000 0,01409491 0,04189035 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01409491 0,04183945 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01409491 0,04178868 ! eating behavior GO:0042755 8 7 0,000 0,01409491 0,04173802 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01409491 0,04168749 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01409491 0,04163709 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01409491 0,0415868 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01409491 0,04153663 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01409491 0,04148659 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01409491 0,04143667 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01409491 0,04138686 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01409491 0,04133718 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01409491 0,04128761 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01409491 0,04123817 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01409491 0,04118884 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01409491 0,04113963 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01409491 0,04109054 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01409491 0,04104156 ! histone ubiquitination GO:0016574 9 7 0,000 0,01409491 0,0409927 ! regulation of meiosis GO:0040020 12 7 0,000 0,01409491 0,04094396 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01409491 0,04089533 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01409491 0,04084682 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01409491 0,04079842 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01409491 0,04075014 ! transcription termination GO:0006353 14 7 0,000 0,01409491 0,04070197 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01409491 0,04065392 ! anaphase GO:0051322 18 7 0,000 0,01409491 0,04060598 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01409491 0,04055815 ! axonal fasciculation GO:0007413 19 7 0,000 0,01409491 0,04051044 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01409491 0,04046283 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01409491 0,04041534 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01409491 0,04036796 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01409491 0,04032069 ! diuresis GO:0030146 12 7 0,000 0,01409491 0,04027353 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01409491 0,04022648 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01409491 0,04017955 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01409491 0,04013272 ! antibiotic transport GO:0042891 9 7 0,000 0,01409491 0,040086 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01409491 0,04003938 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01409491 0,03999288 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01409491 0,03994649 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01409491 0,0399002 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01409491 0,03985402 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01409491 0,03980794 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01409491 0,03976197 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01409491 0,03971611 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01409491 0,03967036 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01409491 0,03962471 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01409491 0,03957916 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01409491 0,03953372 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01409491 0,03948838 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01409491 0,03944315 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01409491 0,03939802 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01409491 0,03935299 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01409491 0,03930807 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01409491 0,03926325 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01409491 0,03921853 ! muscle adaptation GO:0043500 13 7 0,000 0,01409491 0,03917391 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01409491 0,0391294 ! retina homeostasis GO:0001895 12 7 0,000 0,01409491 0,03908498 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01409491 0,03904067 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01409491 0,03899646 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01409491 0,03895234 ! regulation of DNA binding GO:0051101 167 89 1,000 0,01414426 0,03904454 ! protein localization in nucleus GO:0034504 192 89 1,000 0,01414426 0,03900048 ! cellular defense response GO:0006968 123 89 1,000 0,01414426 0,03895651 ! ossification GO:0001503 205 91 1,000 0,01475247 0,04058591 ! bone development GO:0060348 206 92 1,000 0,01506076 0,04138744 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01609241 0,04417277 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01609241 0,04412319 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01609241 0,04407373 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01609241 0,04402437 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01609241 0,04397513 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01609241 0,04392599 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01609241 0,04387697 ! male meiosis GO:0007140 9 8 0,000 0,01609241 0,04382805 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01609241 0,04377925 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01609241 0,04373055 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01609241 0,04368196 ! meiotic prophase I GO:0007128 14 8 0,000 0,01609241 0,04363348 ! response to zinc ion GO:0010043 12 8 0,000 0,01609241 0,0435851 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01609241 0,04353684 ! oligopeptide transport GO:0006857 16 8 0,000 0,01609241 0,04348868 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01609241 0,04344062 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01609241 0,04339267 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01609241 0,04334483 ! signal peptide processing GO:0006465 12 8 0,000 0,01609241 0,0432971 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01609241 0,04324946 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01609241 0,04320194 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01609241 0,04315452 ! succinate metabolic process GO:0006105 17 8 0,000 0,01609241 0,0431072 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01609241 0,04305998 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01609241 0,04301287 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01609241 0,04296586 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01609241 0,04291896 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01609241 0,04287215 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01609241 0,04282545 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01609241 0,04277885 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01609241 0,04273235 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01609241 0,04268595 ! reflex GO:0060004 17 8 0,000 0,01609241 0,04263966 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01609241 0,04259346 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01609241 0,04254736 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01609241 0,04250137 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01609241 0,04245547 ! pigment granule organization GO:0048753 17 8 0,000 0,01609241 0,04240967 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01609241 0,04236397 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01609241 0,04231837 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01609241 0,04227286 ! histidine catabolic process GO:0006548 10 8 0,000 0,01609241 0,04222746 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01609241 0,04218215 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01609241 0,04213694 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01609241 0,04209182 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01609241 0,04204681 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01609241 0,04200188 ! melanin metabolic process GO:0006582 17 8 0,000 0,01609241 0,04195706 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01609241 0,04191233 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01609241 0,04186769 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01609241 0,04182315 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01609241 0,04177871 ! macrophage activation GO:0042116 13 8 0,000 0,01609241 0,04173436 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01609241 0,0416901 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01609241 0,04164594 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01609241 0,04160187 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01609241 0,04155789 ! purine salvage GO:0043101 12 8 0,000 0,01609241 0,04151401 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01609241 0,04147021 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01609241 0,04142652 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01609241 0,04138291 ! osteoblast development GO:0002076 17 8 0,000 0,01609241 0,04133939 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01609241 0,04129597 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01609241 0,04125264 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01609241 0,0412094 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01609241 0,04116624 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01609241 0,04112318 ! response to UV-B GO:0010224 17 8 0,000 0,01609241 0,04108021 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01609241 0,04103733 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01609241 0,04099454 ! intermediate filament organization GO:0045109 12 8 0,000 0,01609241 0,04095184 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01609241 0,04090922 ! cellular extravasation GO:0045123 13 8 0,000 0,01609241 0,0408667 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01609241 0,04082426 ! response to antibiotic GO:0046677 11 8 0,000 0,01609241 0,04078191 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01609241 0,04073965 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01609241 0,04069748 ! DNA topological change GO:0006265 12 8 0,000 0,01609241 0,04065539 ! response to tropane GO:0014073 15 8 0,000 0,01609241 0,04061339 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01609241 0,04057148 ! melanosome transport GO:0032402 13 8 0,000 0,01609241 0,04052965 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01609241 0,04048791 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01609241 0,04044626 ! mast cell activation GO:0045576 14 8 0,000 0,01609241 0,04040469 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01609241 0,04036321 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01609241 0,04032181 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01609241 0,0402805 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01609241 0,04023927 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01609241 0,04019812 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01609241 0,04015706 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01609241 0,04011608 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01609241 0,04007519 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01609241 0,04003438 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01609241 0,03999366 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01609241 0,03995301 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01609241 0,03991245 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01609241 0,03987197 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01609241 0,03983157 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01609241 0,03979126 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01609241 0,03975102 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01609241 0,03971087 ! hormone catabolic process GO:0042447 17 8 0,000 0,01609241 0,0396708 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01609241 0,03963081 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01609241 0,0395909 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01609241 0,03955107 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01609241 0,03951132 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01609241 0,03947165 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01609241 0,03943206 ! adult feeding behavior GO:0008343 10 8 0,000 0,01609241 0,03939255 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01609241 0,03935312 ! ATP catabolic process GO:0006200 11 8 0,000 0,01609241 0,03931376 ! blastocyst growth GO:0001832 19 8 0,000 0,01609241 0,03927449 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01609241 0,03923529 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01609241 0,03919617 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01609241 0,03915713 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01609241 0,03911817 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01609241 0,03907929 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01609241 0,03904048 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01609241 0,03900175 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01609241 0,0389631 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01609241 0,03892452 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01609241 0,03888602 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01609241 0,03884759 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01609241 0,03880924 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01609241 0,03877097 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01609241 0,03873277 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01609241 0,03869465 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01609241 0,0386566 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01609241 0,03861863 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01609241 0,03858073 ! regulation of protein localization GO:0032880 188 97 1,000 0,01664355 0,03986293 ! axon extension GO:0048675 16 9 0,000 0,01808592 0,04327513 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01808592 0,04323279 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01808592 0,04319052 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01808592 0,04314835 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01808592 0,04310625 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01808592 0,04306424 ! reproductive behavior GO:0019098 22 9 0,000 0,01808592 0,0430223 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01808592 0,04298045 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01808592 0,04293868 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01808592 0,042897 ! UTP metabolic process GO:0046051 10 9 0,000 0,01808592 0,04285539 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01808592 0,04281386 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01808592 0,04277242 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01808592 0,04273105 ! artery development GO:0060840 25 9 0,000 0,01808592 0,04268976 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01808592 0,04264856 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01808592 0,04260743 ! equilibrioception GO:0050957 20 9 0,000 0,01808592 0,04256638 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01808592 0,04252542 ! chemosensory behavior GO:0007635 21 9 0,000 0,01808592 0,04248453 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01808592 0,04244371 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01808592 0,04240298 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01808592 0,04236233 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01808592 0,04232175 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01808592 0,04228125 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01808592 0,04224083 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01808592 0,04220048 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01808592 0,04216022 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01808592 0,04212003 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01808592 0,04207991 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01808592 0,04203987 ! protein targeting to ER GO:0045047 25 9 0,000 0,01808592 0,04199991 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01808592 0,04196003 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01808592 0,04192021 ! T cell selection GO:0045058 27 9 0,000 0,01808592 0,04188048 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01808592 0,04184082 ! glycine catabolic process GO:0006546 15 9 0,000 0,01808592 0,04180124 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01808592 0,04176173 ! endosome organization GO:0007032 20 9 0,000 0,01808592 0,04172229 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01808592 0,04168293 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01808592 0,04164364 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01808592 0,04160443 ! mannose metabolic process GO:0006013 13 9 0,000 0,01808592 0,04156529 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01808592 0,04152623 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01808592 0,04148724 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01808592 0,04144832 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01808592 0,04140947 ! receptor clustering GO:0043113 20 9 0,000 0,01808592 0,0413707 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01808592 0,041332 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01808592 0,04129337 ! retinol metabolic process GO:0042572 20 9 0,000 0,01808592 0,04125481 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01808592 0,04121633 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01808592 0,04117792 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01808592 0,04113958 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01808592 0,04110131 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01808592 0,04106311 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01808592 0,04102498 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01808592 0,04098693 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01808592 0,04094894 ! response to amine stimulus GO:0014075 13 9 0,000 0,01808592 0,04091102 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01808592 0,04087318 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01808592 0,0408354 ! erythrocyte development GO:0048821 17 9 0,000 0,01808592 0,0407977 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01808592 0,04076006 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01808592 0,04072249 ! renal water homeostasis GO:0003091 15 9 0,000 0,01808592 0,040685 ! postreplication repair GO:0006301 25 9 0,000 0,01808592 0,04064757 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01808592 0,04061021 ! icosanoid secretion GO:0032309 15 9 0,000 0,01808592 0,04057292 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01808592 0,04053569 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01808592 0,04049854 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01808592 0,04046145 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01808592 0,04042443 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01808592 0,04038748 ! sterol catabolic process GO:0016127 14 9 0,000 0,01808592 0,0403506 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01808592 0,04031378 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01808592 0,04027703 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01808592 0,04024035 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01808592 0,04020374 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01808592 0,04016719 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01808592 0,04013071 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01808592 0,04009429 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01808592 0,04005794 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01808592 0,04002165 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01808592 0,03998544 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01808592 0,03994928 ! purine base metabolic process GO:0006144 25 9 0,000 0,01808592 0,03991319 ! pigment granule transport GO:0051904 17 9 0,000 0,01808592 0,03987717 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01808592 0,03984121 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01808592 0,03980532 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01808592 0,03976949 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01808592 0,03973373 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01808592 0,03969803 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01808592 0,03966239 ! mitochondrion localization GO:0051646 18 9 0,000 0,01808592 0,03962682 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02007545 0,04394652 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02007545 0,04390718 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02007545 0,04386791 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02007545 0,0438287 ! associative learning GO:0008306 21 10 0,000 0,02007545 0,04378957 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02007545 0,04375051 ! phosphate transport GO:0006817 24 10 0,000 0,02007545 0,04371151 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02007545 0,04367259 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02007545 0,04363374 ! CTP metabolic process GO:0046036 11 10 0,000 0,02007545 0,04359495 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02007545 0,04355623 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02007545 0,04351759 ! GTP metabolic process GO:0046039 11 10 0,000 0,02007545 0,04347901 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02007545 0,0434405 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02007545 0,04340205 ! social behavior GO:0035176 29 10 0,000 0,02007545 0,04336368 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02007545 0,04332537 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02007545 0,04328713 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02007545 0,04324896 ! androgen metabolic process GO:0008209 17 10 0,000 0,02007545 0,04321085 ! phospholipid efflux GO:0033700 19 10 0,000 0,02007545 0,04317282 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02007545 0,04313485 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02007545 0,04309694 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02007545 0,0430591 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02007545 0,04302133 ! lung alveolus development GO:0048286 26 10 0,000 0,02007545 0,04298363 ! pathogenesis GO:0009405 17 10 0,000 0,02007545 0,04294599 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02007545 0,04290842 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02007545 0,04287091 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02007545 0,04283347 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02007545 0,04279609 ! endoderm development GO:0007492 18 10 0,000 0,02007545 0,04275878 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02007545 0,04272153 ! arginine catabolic process GO:0006527 17 10 0,000 0,02007545 0,04268435 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02007545 0,04264723 ! proline metabolic process GO:0006560 13 10 0,000 0,02007545 0,04261018 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02007545 0,04257319 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02007545 0,04253627 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02007545 0,04249941 ! V(D)J recombination GO:0033151 34 10 0,000 0,02007545 0,04246261 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02007545 0,04242588 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02007545 0,04238921 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02007545 0,04235261 ! B cell proliferation GO:0042100 19 10 0,000 0,02007545 0,04231606 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02007545 0,04227959 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02007545 0,04224317 ! multicellular organism growth GO:0035264 19 10 0,000 0,02007545 0,04220681 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02007545 0,04217052 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02007545 0,04213429 ! ruffle organization GO:0031529 17 10 0,000 0,02007545 0,04209813 ! epithelial cell development GO:0002064 21 10 0,000 0,02007545 0,04206202 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02007545 0,04202598 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02007545 0,04199 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02007545 0,04195408 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02007545 0,04191822 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02007545 0,04188242 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02007545 0,04184669 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,02007545 0,04181101 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02007545 0,0417754 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02007545 0,04173985 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02007545 0,04170435 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02007545 0,04166892 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02007545 0,04163355 ! segment specification GO:0007379 15 10 0,000 0,02007545 0,04159823 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02007545 0,04156298 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02007545 0,04152779 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02007545 0,04149266 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02007545 0,04145758 ! response to dsRNA GO:0043331 23 10 0,000 0,02007545 0,04142257 ! DNA ligation GO:0006266 18 10 0,000 0,02007545 0,04138761 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02007545 0,04135271 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02007545 0,04131788 ! melanosome localization GO:0032400 16 10 0,000 0,02007545 0,0412831 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02007545 0,04124838 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02007545 0,04121371 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02007545 0,04117911 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02007545 0,04114456 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02007545 0,04111007 ! induction of an organ GO:0001759 17 10 0,000 0,02007545 0,04107564 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02007545 0,04104127 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02007545 0,04100696 ! protein sumoylation GO:0016925 17 10 0,000 0,02007545 0,0409727 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02007545 0,0409385 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02007545 0,04090435 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02007545 0,04087027 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02007545 0,04083624 ! salivary gland development GO:0007431 28 10 0,000 0,02007545 0,04080226 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02007545 0,04076834 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02007545 0,04073448 ! midbrain development GO:0030901 14 10 0,000 0,02007545 0,04070068 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02007545 0,04066693 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02007545 0,04063324 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02007545 0,0405996 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02007545 0,04056602 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02007545 0,04053249 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02007545 0,04049902 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02007545 0,04046561 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02007545 0,04043225 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02007545 0,04039894 ! detection of calcium ion GO:0005513 24 10 0,000 0,02007545 0,04036569 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02007545 0,0403325 ! blastocyst formation GO:0001825 18 10 0,000 0,02007545 0,04029936 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02007545 0,04026627 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02007545 0,04023324 ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02007545 0,04020026 ! response to nicotine GO:0035094 20 10 0,000 0,02007545 0,04016734 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02007545 0,04013447 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02007545 0,04010165 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,022061 0,04403188 ! respiratory burst GO:0045730 17 11 0,000 0,022061 0,04399593 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,022061 0,04396005 ! neuron fate specification GO:0048665 18 11 0,000 0,022061 0,04392422 ! telencephalon cell migration GO:0022029 23 11 0,000 0,022061 0,04388845 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,022061 0,04385274 ! thyroid gland development GO:0030878 26 11 0,000 0,022061 0,04381709 ! synapsis GO:0007129 14 11 0,000 0,022061 0,04378149 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,022061 0,04374596 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,022061 0,04371048 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,022061 0,04367506 ! response to pain GO:0048265 27 11 0,000 0,022061 0,04363969 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,022061 0,04360439 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,022061 0,04356913 ! blood vessel remodeling GO:0001974 30 11 0,000 0,022061 0,04353394 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,022061 0,04349881 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,022061 0,04346373 ! bone resorption GO:0045453 16 11 0,000 0,022061 0,0434287 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,022061 0,04339374 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,022061 0,04335883 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,022061 0,04332397 ! melanocyte differentiation GO:0030318 20 11 0,000 0,022061 0,04328917 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,022061 0,04325443 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,022061 0,04321974 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,022061 0,04318511 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,022061 0,04315054 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,022061 0,04311602 ! UV protection GO:0009650 20 11 0,000 0,022061 0,04308155 ! adult heart development GO:0007512 16 11 0,000 0,022061 0,04304714 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,022061 0,04301279 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,022061 0,04297848 ! macroautophagy GO:0016236 19 11 0,000 0,022061 0,04294424 ! temperature homeostasis GO:0001659 18 11 0,000 0,022061 0,04291005 ! behavioral fear response GO:0001662 27 11 0,000 0,022061 0,04287591 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,022061 0,04284183 ! negative regulation of ossification GO:0030279 27 11 0,000 0,022061 0,0428078 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,022061 0,04277383 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,022061 0,0427399 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,022061 0,04270604 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,022061 0,04267222 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,022061 0,04263847 ! regulation of organ growth GO:0046620 14 11 0,000 0,022061 0,04260476 ! pigment granule localization GO:0051875 20 11 0,000 0,022061 0,04257111 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,022061 0,04253751 ! vasoconstriction GO:0042310 20 11 0,000 0,022061 0,04250396 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,022061 0,04247046 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,022061 0,04243702 ! embryonic axis specification GO:0000578 19 11 0,000 0,022061 0,04240363 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,022061 0,0423703 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,022061 0,04233701 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,022061 0,04230378 ! DNA methylation GO:0006306 19 11 0,000 0,022061 0,0422706 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,022061 0,04223748 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,022061 0,0422044 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,022061 0,04217138 ! prophase GO:0051324 17 11 0,000 0,022061 0,0421384 ! neuroblast proliferation GO:0007405 25 11 0,000 0,022061 0,04210548 ! nucleosome positioning GO:0016584 15 11 0,000 0,022061 0,04207262 ! regulation of isotype switching GO:0045191 24 11 0,000 0,022061 0,0420398 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,022061 0,04200703 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,022061 0,04197431 ! apical protein localization GO:0045176 18 11 0,000 0,022061 0,04194165 ! acid secretion GO:0046717 20 11 0,000 0,022061 0,04190904 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,022061 0,04187647 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,022061 0,04184396 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,022061 0,0418115 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,022061 0,04177909 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,022061 0,04174672 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,022061 0,04171441 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,022061 0,04168215 ! cholesterol efflux GO:0033344 21 11 0,000 0,022061 0,04164994 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,022061 0,04161778 ! oocyte development GO:0048599 20 11 0,000 0,022061 0,04158566 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,022061 0,0415536 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,022061 0,04152159 ! embryonic gut development GO:0048566 19 11 0,000 0,022061 0,04148962 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,022061 0,04145771 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,022061 0,04142584 ! activation of innate immune response GO:0002218 16 11 0,000 0,022061 0,04139402 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,022061 0,04136226 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,022061 0,04133054 ! lysogeny GO:0030069 22 11 0,000 0,022061 0,04129887 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,022061 0,04126724 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,022061 0,04123567 ! sequestering of metal ion GO:0051238 15 11 0,000 0,022061 0,04120414 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02404258 0,04487092 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02404258 0,04483666 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02404258 0,04480246 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02404258 0,04476831 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02404258 0,04473422 ! protein complex disassembly GO:0043241 28 12 0,000 0,02404258 0,04470017 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02404258 0,04466618 ! hippocampus development GO:0021766 29 12 0,000 0,02404258 0,04463224 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02404258 0,04459835 ! T cell proliferation GO:0042098 32 12 0,000 0,02404258 0,04456451 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02404258 0,04453073 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02404258 0,04449699 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02404258 0,04446331 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02404258 0,04442967 ! drug transport GO:0015893 16 12 0,000 0,02404258 0,04439609 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02404258 0,04436256 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02404258 0,04432908 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02404258 0,04429565 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02404258 0,04426227 ! focal adhesion formation GO:0048041 37 12 0,000 0,02404258 0,04422894 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02404258 0,04419566 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02404258 0,04416243 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02404258 0,04412925 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02404258 0,04409612 ! lipid digestion GO:0044241 21 12 0,000 0,02404258 0,04406304 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02404258 0,04403001 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02404258 0,04399703 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02404258 0,04396409 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02404258 0,04393121 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02404258 0,04389838 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02404258 0,04386559 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02404258 0,04383286 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02404258 0,04380017 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02404258 0,04376753 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02404258 0,04373494 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02404258 0,0437024 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02404258 0,04366991 ! cranial nerve development GO:0021545 23 12 0,000 0,02404258 0,04363747 ! fucose catabolic process GO:0019317 25 12 0,000 0,02404258 0,04360507 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02404258 0,04357272 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02404258 0,04354042 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02404258 0,04350817 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02404258 0,04347596 ! zymogen activation GO:0031638 18 12 0,000 0,02404258 0,04344381 ! T cell homeostasis GO:0043029 28 12 0,000 0,02404258 0,0434117 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02404258 0,04337964 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02404258 0,04334762 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02404258 0,04331566 ! oocyte differentiation GO:0009994 21 12 0,000 0,02404258 0,04328374 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02404258 0,04325186 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02404258 0,04322004 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02404258 0,04318826 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02404258 0,04315652 ! defense response to fungus GO:0050832 15 12 0,000 0,02404258 0,04312484 ! developmental induction GO:0031128 22 12 0,000 0,02404258 0,0430932 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02404258 0,0430616 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02404258 0,04303006 ! response to cold GO:0009409 17 12 0,000 0,02404258 0,04299856 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02404258 0,0429671 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02404258 0,04293569 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02602021 0,04643343 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02602021 0,04639954 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02602021 0,04636569 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02602021 0,0463319 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02602021 0,04629815 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02602021 0,04626446 ! peroxisomal transport GO:0043574 28 13 0,000 0,02602021 0,04623081 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02602021 0,04619721 ! cartilage condensation GO:0001502 22 13 0,000 0,02602021 0,04616366 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02602021 0,04613016 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02602021 0,04609671 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02602021 0,04606331 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02602021 0,04602995 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02602021 0,04599665 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02602021 0,04596339 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02602021 0,04593018 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02602021 0,04589701 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02602021 0,0458639 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02602021 0,04583083 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02602021 0,04579781 ! methionine metabolic process GO:0006555 31 13 0,000 0,02602021 0,04576484 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02602021 0,04573192 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02602021 0,04569904 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02602021 0,04566621 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,02602021 0,04563343 ! exocrine system development GO:0035272 34 13 0,000 0,02602021 0,04560069 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02602021 0,045568 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02602021 0,04553536 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02602021 0,04550277 ! L-glutamate transport GO:0015813 30 13 0,000 0,02602021 0,04547022 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02602021 0,04543772 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02602021 0,04540526 ! protein homotetramerization GO:0051289 24 13 0,000 0,02602021 0,04537285 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02602021 0,04534049 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02602021 0,04530817 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02602021 0,0452759 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02602021 0,04524368 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02602021 0,0452115 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02602021 0,04517936 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02602021 0,04514728 ! histone methylation GO:0016571 29 13 0,000 0,02602021 0,04511523 ! chromatin silencing GO:0006342 29 13 0,000 0,02602021 0,04508324 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02602021 0,04505129 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02602021 0,04501938 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02602021 0,04498752 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02602021 0,0449557 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02602021 0,04492393 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02602021 0,04489221 ! spleen development GO:0048536 24 13 0,000 0,02602021 0,04486052 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02602021 0,04482889 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02602021 0,0447973 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02602021 0,04476575 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02602021 0,04473425 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02602021 0,04470279 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02602021 0,04467137 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02602021 0,04464 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02602021 0,04460868 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02602021 0,04457739 ! insulin secretion GO:0030073 24 13 0,000 0,02602021 0,04454616 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02602021 0,04451496 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02602021 0,04448381 ! acrosome reaction GO:0007340 19 13 0,000 0,02602021 0,0444527 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02602021 0,04442164 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02602021 0,04439062 ! rRNA transcription GO:0009303 28 14 0,000 0,02799388 0,04772439 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02799388 0,04769111 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02799388 0,04765787 ! water transport GO:0006833 21 14 0,000 0,02799388 0,04762468 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02799388 0,04759154 ! non-recombinational repair GO:0000726 29 14 0,000 0,02799388 0,04755845 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02799388 0,0475254 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02799388 0,04749239 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02799388 0,04745943 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02799388 0,04742652 ! palate development GO:0060021 32 14 0,000 0,02799388 0,04739366 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02799388 0,04736083 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02799388 0,04732806 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02799388 0,04729533 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02799388 0,04726264 ! arginine metabolic process GO:0006525 21 14 0,000 0,02799388 0,04723 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02799388 0,04719741 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02799388 0,04716486 ! regulation of heart rate GO:0002027 25 14 0,000 0,02799388 0,04713235 ! fear response GO:0042596 34 14 0,000 0,02799388 0,04709989 ! organic alcohol transport GO:0015850 29 14 0,000 0,02799388 0,04706748 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02799388 0,04703511 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02799388 0,04700278 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02799388 0,0469705 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02799388 0,04693826 ! bone mineralization GO:0030282 18 14 0,000 0,02799388 0,04690607 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02799388 0,04687392 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02799388 0,04684181 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02799388 0,04680975 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02799388 0,04677773 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02799388 0,04674576 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02799388 0,04671383 ! ribosome assembly GO:0042255 18 14 0,000 0,02799388 0,04668194 ! cerebellum development GO:0021549 23 14 0,000 0,02799388 0,0466501 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02799388 0,0466183 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02799388 0,04658654 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02799388 0,04655483 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02799388 0,04652316 ! NADP metabolic process GO:0006739 24 14 0,000 0,02799388 0,04649153 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02799388 0,04645995 ! oxygen transport GO:0015671 22 14 0,000 0,02799388 0,04642841 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02799388 0,04639691 ! male genitalia development GO:0030539 26 14 0,000 0,02799388 0,04636545 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02799388 0,04633404 ! regulation of axon extension GO:0030516 43 14 0,000 0,02799388 0,04630267 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02799388 0,04627134 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02996361 0,04949364 ! lactation GO:0007595 30 15 0,000 0,02996361 0,0494602 ! reproductive cellular process GO:0048610 22 15 0,000 0,02996361 0,0494268 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02996361 0,04939345 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02996361 0,04936014 ! superoxide anion generation GO:0042554 22 15 0,000 0,02996361 0,04932688 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02996361 0,04929366 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02996361 0,04926049 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02996361 0,04922736 ! copper ion transport GO:0006825 22 15 0,000 0,02996361 0,04919428 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02996361 0,04916124 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02996361 0,04912825 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02996361 0,0490953 ! sulfate transport GO:0008272 27 15 0,000 0,02996361 0,04906239 ! response to cAMP GO:0051591 25 15 0,000 0,02996361 0,04902953 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02996361 0,04899671 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02996361 0,04896394 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02996361 0,04893121 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02996361 0,04889852 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02996361 0,04886588 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02996361 0,04883328 ! vesicle coating GO:0006901 38 15 0,000 0,02996361 0,04880073 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02996361 0,04876822 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02996361 0,04873575 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02996361 0,04870332 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02996361 0,04867094 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02996361 0,0486386 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02996361 0,0486063 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02996361 0,04857405 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02996361 0,04854184 ! histone deacetylation GO:0016575 24 15 0,000 0,02996361 0,04850967 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02996361 0,04847754 ! water homeostasis GO:0030104 28 15 0,000 0,02996361 0,04844546 ! cofactor transport GO:0051181 30 15 0,000 0,02996361 0,04841342 ! muscle maintenance GO:0046716 26 15 0,000 0,02996361 0,04838142 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02996361 0,04834947 ! intestinal absorption GO:0050892 31 15 0,000 0,02996361 0,04831755 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02996361 0,04828568 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02996361 0,04825385 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02996361 0,04822206 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02996361 0,04819032 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,02996361 0,04815861 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02996361 0,04812695 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02996361 0,04809533 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02996361 0,04806375 ! actin filament polymerization GO:0030041 27 15 0,000 0,02996361 0,04803221 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02996361 0,04800072 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,0319294 0,05111633 ! positive regulation of cell size GO:0045793 29 16 0,000 0,0319294 0,05108286 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,0319294 0,05104942 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,0319294 0,05101604 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,0319294 0,05098269 ! bone remodeling GO:0046849 28 16 0,000 0,0319294 0,05094939 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,0319294 0,05091614 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,0319294 0,05088292 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,0319294 0,05084975 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,0319294 0,05081663 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,0319294 0,05078354 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,0319294 0,0507505 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,0319294 0,0507175 ! startle response GO:0001964 28 16 0,000 0,0319294 0,05068455 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,0319294 0,05065164 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,0319294 0,05061877 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,0319294 0,05058594 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,0319294 0,05055316 ! protein polyubiquitination GO:0000209 41 16 0,000 0,0319294 0,05052041 ! glutamate metabolic process GO:0006536 25 16 0,000 0,0319294 0,05048772 ! pituitary gland development GO:0021983 30 16 0,000 0,0319294 0,05045506 ! response to osmotic stress GO:0006970 27 16 0,000 0,0319294 0,05042244 ! lysosomal transport GO:0007041 31 16 0,000 0,0319294 0,05038987 ! fructose metabolic process GO:0006000 25 16 0,000 0,0319294 0,05035734 ! L-amino acid transport GO:0015807 33 16 0,000 0,0319294 0,05032485 ! stem cell development GO:0048864 46 16 0,000 0,0319294 0,05029241 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0319294 0,05026 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0319294 0,05022764 ! intermediate filament-based process GO:0045103 36 16 0,000 0,0319294 0,05019532 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,0319294 0,05016304 ! negative regulation of immune response GO:0050777 38 16 0,000 0,0319294 0,0501308 ! axon cargo transport GO:0008088 46 16 0,000 0,0319294 0,0500986 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,0319294 0,05006644 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,0319294 0,05003433 ! DNA replication initiation GO:0006270 28 16 0,000 0,0319294 0,05000226 ! neuron recognition GO:0008038 40 16 0,000 0,0319294 0,04997022 ! mRNA splice site selection GO:0006376 44 16 0,000 0,0319294 0,04993823 ! tissue regeneration GO:0042246 27 16 0,000 0,0319294 0,04990628 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,0319294 0,04987437 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,0319294 0,04984251 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,0319294 0,04981068 ! biomineral formation GO:0031214 22 16 0,000 0,0319294 0,04977889 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,0319294 0,04974714 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,0319294 0,04971544 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,0319294 0,04968377 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0319294 0,04965215 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,0319294 0,04962056 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,0319294 0,04958901 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,0319294 0,04955751 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,0319294 0,04952604 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,0319294 0,04949462 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03389126 0,05250244 ! metencephalon development GO:0022037 32 17 0,000 0,03389126 0,05246917 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03389126 0,05243594 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03389126 0,05240275 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03389126 0,05236961 ! endothelial cell migration GO:0043542 31 17 0,000 0,03389126 0,05233651 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03389126 0,05230344 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03389126 0,05227042 ! glial cell development GO:0021782 28 17 0,000 0,03389126 0,05223745 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03389126 0,05220451 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03389126 0,05217161 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03389126 0,05213876 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03389126 0,05210595 ! myoblast differentiation GO:0045445 50 17 0,000 0,03389126 0,05207318 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03389126 0,05204045 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03389126 0,05200776 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03389126 0,05197511 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03389126 0,0519425 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03389126 0,05190994 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03389126 0,05187741 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03389126 0,05184493 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03389126 0,05181249 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03389126 0,05178008 ! membrane budding GO:0006900 42 17 0,000 0,03389126 0,05174772 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03389126 0,0517154 ! regulation of protein binding GO:0043393 33 17 0,000 0,03389126 0,05168312 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03389126 0,05165088 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03389126 0,05161867 ! genitalia development GO:0048806 32 17 0,000 0,03389126 0,05158651 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03389126 0,05155439 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03389126 0,05152231 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03389126 0,05149027 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03389126 0,05145827 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03389126 0,05142631 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03389126 0,05139438 ! steroid catabolic process GO:0006706 34 17 0,000 0,03389126 0,0513625 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03389126 0,05133066 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03389126 0,05129886 ! gas transport GO:0015669 26 17 0,000 0,03389126 0,05126709 ! organic cation transport GO:0015695 32 17 0,000 0,03389126 0,05123537 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03389126 0,05120368 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03389126 0,05117204 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03389126 0,05114043 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,0358492 0,05406149 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,0358492 0,05402813 ! limbic system development GO:0021761 40 18 0,000 0,0358492 0,05399483 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0358492 0,05396156 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,0358492 0,05392833 ! adult walking behavior GO:0007628 36 18 0,000 0,0358492 0,05389514 ! patterning of blood vessels GO:0001569 43 18 0,000 0,0358492 0,053862 ! heart looping GO:0001947 34 18 0,000 0,0358492 0,05382889 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,0358492 0,05379583 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,0358492 0,0537628 ! centrosome cycle GO:0007098 26 18 0,000 0,0358492 0,05372982 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,0358492 0,05369688 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,0358492 0,05366397 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,0358492 0,05363111 ! glycine metabolic process GO:0006544 30 18 0,000 0,0358492 0,05359829 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0358492 0,05356551 ! response to retinoic acid GO:0032526 31 18 0,000 0,0358492 0,05353277 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,0358492 0,05350007 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,0358492 0,0534674 ! DNA integration GO:0015074 32 18 0,000 0,0358492 0,05343478 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,0358492 0,0534022 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,0358492 0,05336966 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,0358492 0,05333715 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,0358492 0,05330469 ! neural crest cell migration GO:0001755 41 18 0,000 0,0358492 0,05327227 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,0358492 0,05323988 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,0358492 0,05320754 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,0358492 0,05317523 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,0358492 0,05314297 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,0358492 0,05311074 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,0358492 0,05307855 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,0358492 0,0530464 ! detection of bacterium GO:0016045 22 18 0,000 0,0358492 0,05301429 ! nerve development GO:0021675 34 18 0,000 0,0358492 0,05298222 ! defense response to virus GO:0051607 43 18 0,000 0,0358492 0,05295019 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,0358492 0,05291819 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,0358492 0,05288624 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03780323 0,05573525 ! positive regulation of translation GO:0045727 31 19 0,000 0,03780323 0,05570163 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03780323 0,05566805 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,03780323 0,05563452 ! neuron maturation GO:0042551 46 19 0,000 0,03780323 0,05560102 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03780323 0,05556757 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,03780323 0,05553416 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03780323 0,05550078 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03780323 0,05546745 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03780323 0,05543415 ! inositol metabolic process GO:0006020 33 19 0,000 0,03780323 0,0554009 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03780323 0,05536769 ! memory GO:0007613 34 19 0,000 0,03780323 0,05533451 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03780323 0,05530138 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03780323 0,05526828 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03780323 0,05523523 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03780323 0,05520221 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,03780323 0,05516924 ! cerebral cortex development GO:0021987 40 19 0,000 0,03780323 0,0551363 ! pigmentation during development GO:0048066 42 19 0,000 0,03780323 0,0551034 ! response to vitamin A GO:0033189 32 19 0,000 0,03780323 0,05507054 ! heme metabolic process GO:0042168 40 19 0,000 0,03780323 0,05503772 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03780323 0,05500494 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03780323 0,0549722 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03780323 0,0549395 ! response to fungus GO:0009620 26 19 0,000 0,03780323 0,05490684 ! peptide cross-linking GO:0018149 39 19 0,000 0,03780323 0,05487421 ! protein export from nucleus GO:0006611 40 19 0,000 0,03780323 0,05484163 ! heart process GO:0003015 32 19 0,000 0,03780323 0,05480908 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,03780323 0,05477657 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03780323 0,0547441 ! visual learning GO:0008542 38 19 0,000 0,03780323 0,05471167 ! cellular pigmentation GO:0033059 37 19 0,000 0,03780323 0,05467928 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03780323 0,05464692 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03780323 0,05461461 ! vitamin transport GO:0051180 31 19 0,000 0,03780323 0,05458233 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03780323 0,05455009 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03780323 0,05451789 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,03780323 0,05448572 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03780323 0,0544536 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03780323 0,05442151 ! cilium assembly GO:0042384 38 19 0,000 0,03780323 0,05438946 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03780323 0,05435745 ! protein secretion GO:0009306 45 20 0,000 0,03975336 0,05712791 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,03975336 0,05709433 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,03975336 0,05706078 ! positive regulation of ossification GO:0045778 50 20 0,000 0,03975336 0,05702728 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,03975336 0,05699381 ! skin development GO:0043588 42 20 0,000 0,03975336 0,05696038 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,03975336 0,056927 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,03975336 0,05689365 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,03975336 0,05686034 ! response to vitamin GO:0033273 36 20 0,000 0,03975336 0,05682707 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,03975336 0,05679383 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,03975336 0,05676064 ! bile acid metabolic process GO:0008206 34 20 0,000 0,03975336 0,05672749 ! response to alkaloid GO:0043279 38 20 0,000 0,03975336 0,05669437 ! retinoid metabolic process GO:0001523 34 20 0,000 0,03975336 0,05666129 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,03975336 0,05662825 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,03975336 0,05659525 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,03975336 0,05656229 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,03975336 0,05652937 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,03975336 0,05649648 ! actin filament bundle formation GO:0051017 47 20 0,000 0,03975336 0,05646364 ! body fluid secretion GO:0007589 33 20 0,000 0,03975336 0,05643083 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,03975336 0,05639806 ! peptide secretion GO:0002790 38 20 0,000 0,03975336 0,05636532 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,03975336 0,05633263 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,03975336 0,05629997 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,03975336 0,05626736 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,03975336 0,05623477 ! cell-cell junction organization GO:0045216 43 20 0,000 0,03975336 0,05620223 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,03975336 0,05616973 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,03975336 0,05613726 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,03975336 0,05610483 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,03975336 0,05607243 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,03975336 0,05604008 ! regulation of glucose import GO:0046324 30 20 0,000 0,03975336 0,05600776 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,03975336 0,05597548 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,03975336 0,05594323 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,03975336 0,05591103 ! negative regulation of translation GO:0017148 32 20 0,000 0,03975336 0,05587886 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,03975336 0,05584673 ! regulation of cell killing GO:0031341 46 21 0,000 0,04169959 0,05854718 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04169959 0,05851355 ! hormone secretion GO:0046879 39 21 0,000 0,04169959 0,05847996 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04169959 0,05844641 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04169959 0,05841289 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04169959 0,05837942 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04169959 0,05834598 ! ovarian follicle development GO:0001541 39 21 0,000 0,04169959 0,05831259 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04169959 0,05827923 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04169959 0,0582459 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04169959 0,05821262 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04169959 0,05817938 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04169959 0,05814617 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04169959 0,058113 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04169959 0,05807987 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,04169959 0,05804677 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04169959 0,05801372 ! diencephalon development GO:0021536 36 21 0,000 0,04169959 0,0579807 ! collagen fibril organization GO:0030199 62 21 0,000 0,04169959 0,05794772 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04169959 0,05791477 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04169959 0,05788187 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04169959 0,057849 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04169959 0,05781617 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,04169959 0,05778337 ! collagen catabolic process GO:0030574 29 21 0,000 0,04169959 0,05775062 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04169959 0,0577179 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04169959 0,05768521 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04169959 0,05765257 ! actin filament-based movement GO:0030048 47 21 0,000 0,04169959 0,05761996 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04364192 0,06026977 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04364192 0,06023571 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04364192 0,0602017 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04364192 0,06016773 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04364192 0,06013379 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04364192 0,0600999 ! microtubule-based transport GO:0010970 59 22 0,000 0,04364192 0,06006604 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04364192 0,06003222 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04364192 0,05999843 ! vacuolar transport GO:0007034 41 22 0,000 0,04364192 0,05996469 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04364192 0,05993098 ! fucose metabolic process GO:0006004 44 22 0,000 0,04364192 0,05989731 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04364192 0,05986368 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04364192 0,05983009 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04364192 0,05979653 ! ureteric bud development GO:0001657 50 22 0,000 0,04364192 0,05976301 ! stem cell differentiation GO:0048863 57 22 0,000 0,04364192 0,05972953 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04364192 0,05969609 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04364192 0,05966268 ! cytolysis GO:0019835 27 22 0,000 0,04364192 0,05962932 ! renal system process GO:0003014 42 22 0,000 0,04364192 0,05959598 ! vasodilation GO:0042311 40 22 0,000 0,04364192 0,05956269 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04364192 0,05952943 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04364192 0,05949621 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,04364192 0,05946303 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04364192 0,05942989 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04364192 0,05939678 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04364192 0,05936371 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04364192 0,05933067 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04364192 0,05929767 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04364192 0,05926471 ! sarcomere organization GO:0045214 32 22 0,000 0,04364192 0,05923179 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04364192 0,0591989 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04364192 0,05916605 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04364192 0,05913323 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04364192 0,05910045 ! gut development GO:0048565 44 22 0,000 0,04364192 0,05906771 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04364192 0,059035 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04364192 0,05900233 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04364192 0,0589697 ! protein stabilization GO:0050821 41 22 0,000 0,04364192 0,0589371 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,04558038 0,06152092 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,04558038 0,06148695 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,04558038 0,06145301 ! gluconeogenesis GO:0006094 38 23 0,000 0,04558038 0,06141912 ! glycerol metabolic process GO:0006071 40 23 0,000 0,04558038 0,06138526 ! viral genome replication GO:0019079 44 23 0,000 0,04558038 0,06135144 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,04558038 0,06131765 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,04558038 0,06128391 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,04558038 0,0612502 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,04558038 0,06121653 ! regeneration GO:0031099 42 23 0,000 0,04558038 0,06118289 ! axis specification GO:0009798 43 23 0,000 0,04558038 0,06114929 ! visual behavior GO:0007632 46 23 0,000 0,04558038 0,06111573 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,04558038 0,06108221 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,04558038 0,06104872 ! response to ethanol GO:0045471 47 23 0,000 0,04558038 0,06101527 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,04558038 0,06098185 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,04558038 0,06094847 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,04558038 0,06091513 ! peroxisome organization GO:0007031 43 23 0,000 0,04558038 0,06088183 ! lysosome organization GO:0007040 47 23 0,000 0,04558038 0,06084856 ! vesicle targeting GO:0006903 49 23 0,000 0,04558038 0,06081532 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,04558038 0,06078213 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,04558038 0,06074897 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,04558038 0,06071585 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,04558038 0,06068276 ! DNA modification GO:0006304 36 23 0,000 0,04558038 0,06064971 ! fatty acid transport GO:0015908 47 23 0,000 0,04558038 0,06061669 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,04558038 0,06058371 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,04558038 0,06055077 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,04558038 0,06051786 ! hormone transport GO:0009914 41 23 0,000 0,04558038 0,06048499 ! cell-cell recognition GO:0009988 28 23 0,000 0,04558038 0,06045215 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,04558038 0,06041935 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,04558038 0,06038658 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,04558038 0,06035385 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,04751496 0,06288139 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,04751496 0,06284734 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,04751496 0,06281333 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,04751496 0,06277936 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,04751496 0,06274543 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,04751496 0,06271153 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,04751496 0,06267767 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,04751496 0,06264384 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,04751496 0,06261005 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,04751496 0,0625763 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,04751496 0,06254259 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,04751496 0,06250891 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,04751496 0,06247526 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,04751496 0,06244166 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,04751496 0,06240809 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,04751496 0,06237455 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,04751496 0,06234105 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,04751496 0,06230759 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,04751496 0,06227416 ! pallium development GO:0021543 56 24 0,000 0,04751496 0,06224077 ! oogenesis GO:0048477 44 24 0,000 0,04751496 0,06220742 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,04751496 0,0621741 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,04751496 0,06214081 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,04751496 0,06210756 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,04751496 0,06207435 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,04751496 0,06204118 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,04751496 0,06200803 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,04751496 0,06197493 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,04751496 0,06194186 ! regulation of amine transport GO:0051952 41 24 0,000 0,04751496 0,06190882 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,04944567 0,06439007 ! leukocyte adhesion GO:0007159 55 25 0,000 0,04944567 0,06435576 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,04944567 0,0643215 ! phototransduction GO:0007602 37 25 0,000 0,04944567 0,06428726 ! keratinization GO:0031424 37 25 0,000 0,04944567 0,06425307 ! vacuole organization GO:0007033 49 25 0,000 0,04944567 0,06421891 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,04944567 0,06418479 ! receptor metabolic process GO:0043112 53 25 0,000 0,04944567 0,0641507 ! chromosome condensation GO:0030261 48 25 0,000 0,04944567 0,06411665 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,04944567 0,06408264 ! regulation of behavior GO:0050795 48 25 0,000 0,04944567 0,06404866 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,04944567 0,06401472 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,04944567 0,06398081 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,04944567 0,06394694 ! immunoglobulin production GO:0002377 62 25 0,000 0,04944567 0,06391311 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,04944567 0,06387931 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,04944567 0,06384554 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,04944567 0,06381182 ! liver development GO:0001889 55 25 0,000 0,04944567 0,06377813 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05137252 0,06622853 ! myelination GO:0042552 50 26 0,000 0,05137252 0,0661936 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05137252 0,06615871 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05137252 0,06612385 ! molting cycle process GO:0022404 52 26 0,000 0,05137252 0,06608903 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05137252 0,06605425 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05137252 0,0660195 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05137252 0,06598479 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05137252 0,06595012 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05137252 0,06591548 ! digestive system process GO:0022600 49 26 0,000 0,05137252 0,06588088 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05137252 0,06584631 ! osteoblast differentiation GO:0001649 63 26 0,000 0,05137252 0,06581178 ! neural crest cell development GO:0014032 59 26 0,000 0,05137252 0,06577729 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05137252 0,06574284 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05137252 0,06570842 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05137252 0,06567403 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05137252 0,06563968 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05137252 0,06560537 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,05137252 0,06557109 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05137252 0,06553685 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,05137252 0,06550265 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05137252 0,06546848 ! blastocyst development GO:0001824 50 26 0,000 0,05137252 0,06543434 ! telomere organization GO:0032200 46 26 0,000 0,05137252 0,06540025 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05137252 0,06536618 ! neural tube closure GO:0001843 58 26 0,000 0,05137252 0,06533216 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05137252 0,06529817 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05137252 0,06526421 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05137252 0,06523029 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,05329552 0,06763687 ! embryonic pattern specification GO:0009880 49 27 0,000 0,05329552 0,06760175 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,05329552 0,06756667 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,05329552 0,06753162 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,05329552 0,06749661 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,05329552 0,06746164 ! iron ion transport GO:0006826 65 27 0,000 0,05329552 0,0674267 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,05329552 0,0673918 ! superoxide metabolic process GO:0006801 41 27 0,000 0,05329552 0,06735694 ! tube lumen formation GO:0035148 59 27 0,000 0,05329552 0,06732211 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,05329552 0,06728732 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,05329552 0,06725257 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,05329552 0,06721785 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,05329552 0,06718316 ! leukocyte proliferation GO:0070661 59 27 0,000 0,05329552 0,06714851 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,05329552 0,0671139 ! neuron fate commitment GO:0048663 52 28 0,000 0,05521468 0,06949483 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,05521468 0,06945905 ! circadian rhythm GO:0007623 56 28 0,000 0,05521468 0,0694233 ! dendrite development GO:0016358 67 28 0,000 0,05521468 0,06938759 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,05521468 0,06935191 ! fat cell differentiation GO:0045444 57 28 0,000 0,05521468 0,06931627 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,05521468 0,06928067 ! sperm motility GO:0030317 37 28 0,000 0,05521468 0,06924511 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,05521468 0,06920958 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,05521468 0,06917409 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,05521468 0,06913863 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,05521468 0,06910321 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,05521468 0,06906783 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,05521468 0,06903248 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,05521468 0,06899717 ! glutathione metabolic process GO:0006749 42 28 0,000 0,05521468 0,0689619 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,05521468 0,06892666 ! lipid oxidation GO:0034440 48 28 0,000 0,05521468 0,06889146 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,05521468 0,06885629 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,05521468 0,06882116 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,05713 0,07117216 ! translational initiation GO:0006413 66 29 0,000 0,05713 0,07113588 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,05713 0,07109964 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,05713 0,07106344 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,05713 0,07102728 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,05713 0,07099115 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,05713 0,07095506 ! primary neural tube formation GO:0014020 61 29 0,000 0,05713 0,070919 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,05713 0,07088299 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,05713 0,070847 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,05713 0,07081106 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,05713 0,07077515 ! synaptogenesis GO:0007416 46 29 0,000 0,05713 0,07073928 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,05713 0,07070344 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,05713 0,07066764 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,05713 0,07063188 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,05713 0,07059616 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,0590415 0,07292132 ! phenol metabolic process GO:0018958 56 30 0,000 0,0590415 0,07288447 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,0590415 0,07284766 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,0590415 0,07281089 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,0590415 0,07277415 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,0590415 0,07273746 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,0590415 0,07270079 ! acute-phase response GO:0006953 50 30 0,000 0,0590415 0,07266417 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,0590415 0,07262758 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,0590415 0,07259103 ! myofibril assembly GO:0030239 50 30 0,000 0,0590415 0,07255451 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,0590415 0,07251804 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,0590415 0,07248159 ! cell fate determination GO:0001709 64 30 0,000 0,0590415 0,07244519 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,0590415 0,07240882 ! phospholipid transport GO:0015914 65 30 0,000 0,0590415 0,07237249 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,0590415 0,0723362 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,0590415 0,07229994 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,0590415 0,07226371 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,0590415 0,07222753 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,0590415 0,07219138 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06094917 0,07448665 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06094917 0,07444941 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06094917 0,0744122 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06094917 0,07437503 ! cell junction assembly GO:0034329 85 31 0,000 0,06094917 0,0743379 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06094917 0,0743008 ! ovulation cycle process GO:0022602 55 31 0,000 0,06094917 0,07426375 ! peptide transport GO:0015833 60 31 0,000 0,06094917 0,07422673 ! male gonad development GO:0008584 56 31 0,000 0,06094917 0,07418974 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06094917 0,0741528 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,06094917 0,07411588 ! detection of light stimulus GO:0009583 44 31 0,000 0,06094917 0,07407901 ! natural killer cell activation GO:0030101 50 31 0,000 0,06094917 0,07404217 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06094917 0,07400537 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06094917 0,07396861 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,06094917 0,07393188 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06094917 0,07389519 ! eye morphogenesis GO:0048592 65 31 0,000 0,06094917 0,07385854 ! response to heat GO:0009408 54 31 0,000 0,06094917 0,07382192 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,06094917 0,07378534 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,06285302 0,07605247 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,06285302 0,07601482 ! collagen metabolic process GO:0032963 49 32 0,000 0,06285302 0,07597721 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,06285302 0,07593963 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,06285302 0,07590209 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,06285302 0,07586459 ! metanephros development GO:0001656 81 32 0,000 0,06285302 0,07582713 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,06285302 0,0757897 ! muscle cell development GO:0055001 52 32 0,000 0,06285302 0,07575231 ! mesoderm formation GO:0001707 73 32 0,000 0,06285302 0,07571496 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,06285302 0,07567764 ! ovulation cycle GO:0042698 57 32 0,000 0,06285302 0,07564036 ! peripheral nervous system development GO:0007422 68 32 0,000 0,06285302 0,07560312 ! BMP signaling pathway GO:0030509 71 32 0,000 0,06285302 0,07556591 ! hindbrain development GO:0030902 65 32 0,000 0,06285302 0,07552874 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,06285302 0,07549161 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,06285302 0,07545451 ! gene silencing GO:0016458 71 32 0,000 0,06285302 0,07541745 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,06475307 0,07765918 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,06475307 0,07762108 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,06475307 0,07758301 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,06475307 0,07754498 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,06475307 0,07750699 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,06475307 0,07746903 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,06475307 0,07743111 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,06475307 0,07739323 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,06475307 0,07735538 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,06664932 0,07958177 ! glial cell differentiation GO:0010001 67 34 0,000 0,06664932 0,07954289 ! post-embryonic development GO:0009791 76 34 0,000 0,06664932 0,07950405 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,06664932 0,07946525 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,06664932 0,07942649 ! spliceosome assembly GO:0000245 75 34 0,000 0,06664932 0,07938776 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,06664932 0,07934907 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,06664932 0,07931042 ! formation of primary germ layer GO:0001704 76 34 0,000 0,06664932 0,07927181 ! cell fate specification GO:0001708 56 34 0,000 0,06664932 0,07923324 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,06664932 0,0791947 ! adult locomotory behavior GO:0008344 62 34 0,000 0,06664932 0,0791562 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,06854178 0,08136423 ! negative regulation of secretion GO:0051048 68 35 0,000 0,06854178 0,08132471 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,06854178 0,08128523 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,06854178 0,08124579 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,06854178 0,08120639 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,06854178 0,08116703 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,06854178 0,0811277 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,06854178 0,08108842 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,06854178 0,08104917 ! ceramide metabolic process GO:0006672 72 35 0,000 0,06854178 0,08100996 ! telencephalon development GO:0021537 81 35 0,000 0,06854178 0,08097078 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,06854178 0,08093165 ! placenta development GO:0001890 53 35 0,000 0,06854178 0,08089255 ! vesicle localization GO:0051648 70 35 0,000 0,06854178 0,08085349 ! regulation of muscle development GO:0048634 82 36 0,000 0,07043046 0,08304132 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,07043046 0,08300126 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,07043046 0,08296124 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,07043046 0,08292126 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,07043046 0,08288132 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,07043046 0,08284141 ! positive regulation of cell development GO:0010720 85 36 0,000 0,07043046 0,08280155 ! protein targeting to membrane GO:0006612 75 36 0,000 0,07043046 0,08276172 ! regulation of proteolysis GO:0030162 77 36 0,000 0,07043046 0,08272193 ! aerobic respiration GO:0009060 56 36 0,000 0,07043046 0,08268218 ! cytokine production GO:0001816 68 36 0,000 0,07043046 0,08264247 ! embryonic organ development GO:0048568 67 36 0,000 0,07043046 0,08260279 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,07043046 0,08256315 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,07043046 0,08252356 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,07231536 0,08469148 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,07231536 0,0846509 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,07231536 0,08461036 ! sister chromatid segregation GO:0000819 65 37 0,000 0,07231536 0,08456985 ! odontogenesis GO:0042476 74 37 0,000 0,07231536 0,08452939 ! actomyosin structure organization GO:0031032 68 37 0,000 0,07231536 0,08448896 ! cell junction organization GO:0034330 96 37 0,000 0,07231536 0,08444858 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,07231536 0,08440823 ! female gonad development GO:0008585 71 37 0,000 0,07231536 0,08436792 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,07231536 0,08432765 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,07231536 0,08428742 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,07231536 0,08424722 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,07419649 0,08639753 ! meiosis I GO:0007127 74 38 0,000 0,07419649 0,08635637 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,07419649 0,08631525 ! organic anion transport GO:0015711 82 38 0,000 0,07419649 0,08627417 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,07419649 0,08623312 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,07419649 0,08619212 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,07419649 0,08615115 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,07419649 0,08611023 ! regulation of protein stability GO:0031647 77 38 0,000 0,07419649 0,08606934 ! spermatid development GO:0007286 69 38 0,000 0,07419649 0,08602849 ! glycogen metabolic process GO:0005977 63 38 0,000 0,07419649 0,08598768 ! pigment metabolic process GO:0042440 87 38 0,000 0,07419649 0,08594691 ! neural tube formation GO:0001841 79 38 0,000 0,07419649 0,08590617 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,07607386 0,0880381 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,07607386 0,08799642 ! negative regulation of binding GO:0051100 71 39 0,000 0,07607386 0,08795477 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,07607386 0,08791317 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,07607386 0,0878716 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,07607386 0,08783007 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,07607386 0,08778859 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,07607386 0,08774714 ! glucan metabolic process GO:0044042 64 39 0,000 0,07607386 0,08770573 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,07794747 0,08982343 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,07794747 0,08978108 ! learning GO:0007612 82 40 0,000 0,07794747 0,08973877 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,07794747 0,0896965 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,07794747 0,08965427 ! mismatch repair GO:0006298 58 40 0,000 0,07794747 0,08961208 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,07794747 0,08956993 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,07794747 0,08952782 ! RNA export from nucleus GO:0006405 61 41 0,000 0,07981734 0,09163241 ! mRNA catabolic process GO:0006402 79 41 0,000 0,07981734 0,09158937 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,07981734 0,09154637 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,07981734 0,09150341 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,07981734 0,09146049 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,07981734 0,09141761 ! gliogenesis GO:0042063 91 41 0,000 0,07981734 0,09137477 ! feeding behavior GO:0007631 69 41 0,000 0,07981734 0,09133197 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,07981734 0,09128921 ! mesenchymal cell development GO:0014031 94 41 0,000 0,07981734 0,0912465 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,07981734 0,09120382 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,07981734 0,09116118 ! spermatid differentiation GO:0048515 73 41 0,000 0,07981734 0,09111858 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,07981734 0,09107602 ! RNA modification GO:0009451 64 41 0,000 0,07981734 0,0910335 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,08168347 0,09311839 ! ear morphogenesis GO:0042471 64 42 0,000 0,08168347 0,09307496 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,08168347 0,09303157 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,08168347 0,09298822 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,08168347 0,09294491 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,08168347 0,09290164 ! regulation of protein secretion GO:0050708 77 42 0,000 0,08168347 0,09285841 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,08168347 0,09281522 ! cytokinesis GO:0000910 84 42 0,000 0,08168347 0,09277207 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,08354586 0,09484319 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,08354586 0,09479914 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,08354586 0,09475513 ! regulation of tube size GO:0035150 76 43 0,000 0,08354586 0,09471116 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,08354586 0,09466723 ! glucose transport GO:0015758 66 43 0,000 0,08354586 0,09462334 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,08354586 0,09457949 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,08354586 0,09453569 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,08354586 0,09449192 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,08354586 0,09444819 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,08354586 0,09440451 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,08354586 0,09436086 ! ion transmembrane transport GO:0034220 79 43 0,000 0,08354586 0,09431726 ! neuron migration GO:0001764 85 43 0,000 0,08354586 0,09427369 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,08354586 0,09423017 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,08540454 0,09628209 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,08540454 0,09623768 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,08540454 0,09619331 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,08540454 0,09614898 ! hexose transport GO:0008645 68 44 0,000 0,08540454 0,09610469 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,08540454 0,09606044 ! striated muscle contraction GO:0006941 85 44 0,000 0,08540454 0,09601624 ! phagocytosis GO:0006909 105 44 0,000 0,08540454 0,09597207 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,08540454 0,09592795 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,08725949 0,09796642 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,08725949 0,09792142 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,08725949 0,09787646 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,08725949 0,09783154 ! biopolymer methylation GO:0043414 91 45 0,000 0,08725949 0,09778667 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,08725949 0,09774183 ! female gamete generation GO:0007292 71 45 0,000 0,08725949 0,09769704 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,08725949 0,09765228 ! polyol metabolic process GO:0019751 77 45 0,000 0,08725949 0,09760757 ! developmental growth GO:0048589 88 45 0,000 0,08725949 0,0975629 ! maintenance of location in cell GO:0051651 101 45 0,000 0,08725949 0,09751827 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,08911073 0,09954162 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,08911073 0,09949613 ! glycolysis GO:0006096 71 46 0,000 0,08911073 0,09945067 ! leukocyte migration GO:0050900 75 46 0,000 0,08911073 0,09940526 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,08911073 0,09935989 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,08911073 0,09931456 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,08911073 0,09926928 ! pigmentation GO:0043473 103 46 0,000 0,08911073 0,09922403 ! cell growth GO:0016049 90 46 0,000 0,08911073 0,09917883 ! neural tube development GO:0021915 91 47 0,000 0,09095828 0,10118901 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,09095828 0,10114295 ! positive regulation of defense response GO:0031349 88 48 0,000 0,09280212 0,10314631 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,09280212 0,1030994 ! cellular component disassembly GO:0022411 89 48 0,000 0,09280212 0,10305254 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,09280212 0,10300572 ! endosome transport GO:0016197 127 48 0,000 0,09280212 0,10295894 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,09280212 0,1029122 ! male sex differentiation GO:0046661 93 48 0,000 0,09280212 0,10286551 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,09280212 0,10281886 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,09280212 0,10277225 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,09280212 0,10272568 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,09280212 0,10267916 ! methylation GO:0032259 97 48 0,000 0,09280212 0,10263268 ! response to calcium ion GO:0051592 94 49 0,000 0,09464228 0,1046204 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,09464228 0,10457308 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,09464228 0,10452581 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,09464228 0,10447858 ! regulation of action potential GO:0001508 102 50 0,000 0,09647876 0,10645782 ! regulation of ion transport GO:0043269 86 50 0,000 0,09647876 0,10640975 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,09647876 0,10636173 ! endocrine system development GO:0035270 109 50 0,000 0,09647876 0,10631376 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,09647876 0,10626583 ! regulation of ossification GO:0030278 123 50 0,000 0,09647876 0,10621794 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,09647876 0,10617009 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,09647876 0,10612229 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,09647876 0,10607453 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,09647876 0,10602681 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,09647876 0,10597914 ! peptide metabolic process GO:0006518 80 51 0,000 0,09831156 0,10794388 ! response to temperature stimulus GO:0009266 84 51 0,000 0,09831156 0,10789539 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,09831156 0,10784694 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,09831156 0,10779854 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,1001407 0,10975492 ! Notch signaling pathway GO:0007219 111 52 0,000 0,1001407 0,10970571 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,1001407 0,10965653 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,1001407 0,1096074 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,1001407 0,10955832 ! excretion GO:0007588 87 52 0,000 0,1001407 0,10950928 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,1001407 0,10946028 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,1001407 0,10941133 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,1001407 0,10936242 ! amino acid activation GO:0043038 98 52 0,000 0,1001407 0,10931355 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,10196618 0,11125653 ! inner ear development GO:0048839 89 53 0,000 0,10196618 0,11120686 ! chromatin remodeling GO:0006338 122 53 0,000 0,10196618 0,11115724 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,10196618 0,11110766 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,10196618 0,11105812 ! cartilage development GO:0051216 99 53 0,000 0,10196618 0,11100863 ! synapse organization GO:0050808 102 53 0,000 0,10196618 0,11095918 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,103788 0,1128914 ! regulation of translational initiation GO:0006446 87 54 0,000 0,103788 0,11284116 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,103788 0,11279097 ! neuromuscular process GO:0050905 107 54 0,000 0,103788 0,11274081 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,103788 0,11269071 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,103788 0,11264064 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,103788 0,11259063 ! regulation of cell shape GO:0008360 142 54 0,000 0,103788 0,11254065 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,103788 0,11249072 ! RNA catabolic process GO:0006401 103 55 0,000 0,10560618 0,1144106 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,10560618 0,11435989 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,10560618 0,11430922 ! cell recognition GO:0008037 98 55 0,000 0,10560618 0,1142586 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,10560618 0,11420802 ! cell maturation GO:0048469 107 55 0,000 0,10560618 0,11415748 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,10560618 0,11410699 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,10742073 0,11601629 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,10742073 0,11596502 ! glucose catabolic process GO:0006007 88 56 0,000 0,10742073 0,1159138 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,10742073 0,11586262 ! RNA elongation GO:0006354 90 56 0,000 0,10742073 0,11581149 ! chloride transport GO:0006821 102 57 0,000 0,10923164 0,11771191 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,10923164 0,11766001 ! muscle fiber development GO:0048747 131 57 0,000 0,10923164 0,11760815 ! regulation of actin filament length GO:0030832 118 58 0,000 0,11103893 0,11950137 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,11103893 0,11944875 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,11103893 0,11939618 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,11103893 0,11934365 ! gastrulation GO:0007369 122 58 0,000 0,11103893 0,11929117 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,11103893 0,11923873 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,11103893 0,11918634 ! maintenance of location GO:0051235 124 58 0,000 0,11103893 0,119134 ! nuclear export GO:0051168 110 59 0,000 0,11284261 0,12101602 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,11464267 0,12289252 ! DNA catabolic process GO:0006308 94 60 0,000 0,11464267 0,12283862 ! regulation of endocytosis GO:0030100 104 60 0,000 0,11464267 0,12278477 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,11464267 0,12273096 ! adult behavior GO:0030534 104 60 0,000 0,11464267 0,1226772 ! kidney development GO:0001822 133 60 0,000 0,11464267 0,12262349 ! positive regulation of secretion GO:0051047 110 61 0,000 0,11643914 0,12449051 ! regulation of cellular component size GO:0032535 125 61 0,000 0,11643914 0,12443605 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,11643914 0,12438164 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,11643914 0,12432728 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,11643914 0,12427296 ! regulation of heart contraction GO:0008016 123 61 0,000 0,11643914 0,12421869 ! camera-type eye development GO:0043010 126 61 0,000 0,11643914 0,12416447 ! proton transport GO:0015992 117 61 0,000 0,11643914 0,1241103 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,11643914 0,12405618 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,11823201 0,12591142 ! tRNA processing GO:0008033 102 62 0,000 0,11823201 0,12585655 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,11823201 0,12580174 ! regulation of mitosis GO:0007088 112 63 0,000 0,12002129 0,12764998 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,12002129 0,12759443 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,12002129 0,12753893 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,12002129 0,12748348 ! hydrogen transport GO:0006818 121 64 0,000 0,12180699 0,12932398 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,12180699 0,1292678 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,12180699 0,12921167 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,12358912 0,13104523 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,12358912 0,13098838 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,12358912 0,13093158 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,12358912 0,13087482 ! ear development GO:0043583 114 66 0,000 0,12536768 0,13270071 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,12536768 0,13264324 ! gonad development GO:0008406 115 66 0,000 0,12536768 0,13258582 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,12536768 0,13252845 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,12714268 0,1343467 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,12714268 0,13428862 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,12714268 0,13423058 ! secondary metabolic process GO:0019748 125 67 0,000 0,12714268 0,1341726 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,12891413 0,13598326 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,12891413 0,13592457 ! hexose catabolic process GO:0019320 113 68 0,000 0,12891413 0,13586593 ! extracellular matrix organization GO:0030198 146 68 0,000 0,12891413 0,13580734 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,12891413 0,1357488 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,12891413 0,13569031 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,12891413 0,13563188 ! adaptive immune response GO:0002250 126 68 0,000 0,12891413 0,13557349 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,12891413 0,13551516 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,13068204 0,1373145 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,13068204 0,13725547 ! urogenital system development GO:0001655 149 69 0,000 0,13068204 0,13719648 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,13068204 0,13713755 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,13068204 0,13707867 ! developmental maturation GO:0021700 128 69 0,000 0,13068204 0,13701983 ! single fertilization GO:0007338 83 69 0,000 0,13068204 0,13696105 ! cell redox homeostasis GO:0045454 114 70 0,000 0,1324464 0,13875067 ! germ cell development GO:0007281 133 70 0,000 0,1324464 0,1386912 ! activation of immune response GO:0002253 120 70 0,000 0,1324464 0,13863177 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,1324464 0,1385724 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,13420724 0,14035457 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,13420724 0,14029451 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,13420724 0,14023451 ! appendage morphogenesis GO:0035107 150 72 0,000 0,13596455 0,14201 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,13596455 0,14194931 ! actin filament organization GO:0007015 167 72 0,000 0,13596455 0,14188868 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,13596455 0,14182809 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,13596455 0,14176756 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,13596455 0,14170708 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,13596455 0,14164665 ! appendage development GO:0048736 151 73 0,000 0,13771834 0,14341258 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,13771834 0,14335147 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,13771834 0,14329042 ! regulation of immune effector process GO:0002697 156 73 0,000 0,13771834 0,14322942 ! acute inflammatory response GO:0002526 118 74 0,000 0,13946862 0,14498802 ! amino acid transport GO:0006865 148 74 0,000 0,13946862 0,14492635 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,13946862 0,14486473 ! transition metal ion transport GO:0000041 143 75 0,000 0,1412154 0,14661676 ! reproductive structure development GO:0048608 131 75 0,000 0,1412154 0,14655447 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,1412154 0,14649224 ! eye development GO:0001654 155 75 0,000 0,1412154 0,14643006 ! axon guidance GO:0007411 162 75 0,000 0,1412154 0,14636794 ! rhythmic process GO:0048511 142 75 0,000 0,1412154 0,14630586 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,14295868 0,1480492 ! learning or memory GO:0007611 161 76 0,000 0,14295868 0,14798647 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,14295868 0,14792379 ! regulation of blood pressure GO:0008217 134 76 0,000 0,14295868 0,14786116 ! amine catabolic process GO:0009310 136 77 0,000 0,14469848 0,14959728 ! neurotransmitter transport GO:0006836 142 77 0,000 0,14469848 0,149534 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,14469848 0,14947077 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,14469848 0,1494076 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,14469848 0,14934448 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,14469848 0,14928141 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,14643479 0,15100894 ! antigen processing and presentation GO:0019882 117 78 0,000 0,14643479 0,15094523 ! fertilization GO:0009566 99 78 0,000 0,14643479 0,15088156 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,14816762 0,15260266 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,14816762 0,15253835 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,14816762 0,15247409 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,14816762 0,15240989 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,14989699 0,15412388 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,14989699 0,15405904 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,14989699 0,15399426 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,14989699 0,15392952 ! meiosis GO:0007126 143 81 0,000 0,15162289 0,15563644 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,15162289 0,15557107 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,15162289 0,15550576 ! meiotic cell cycle GO:0051321 144 82 0,000 0,15334534 0,15720632 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,15506434 0,15890192 ! exocytosis GO:0006887 153 83 0,000 0,15506434 0,15883529 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,15506434 0,15876872 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,15506434 0,15870221 ! inorganic anion transport GO:0015698 156 83 0,000 0,15506434 0,15863575 ! response to metal ion GO:0010038 158 84 0,000 0,15677989 0,16032368 ! response to nutrient GO:0007584 135 84 0,000 0,15677989 0,1602566 ! digestion GO:0007586 130 84 0,000 0,15677989 0,16018958 ! regulation of ligase activity GO:0051340 147 84 0,000 0,15677989 0,16012261 ! negative regulation of transport GO:0051051 164 85 0,000 0,15849202 0,16180359 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,15849202 0,161736 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,15849202 0,16166847 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,15849202 0,161601 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,15849202 0,16153358 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,16020071 0,16320698 ! regulation of lyase activity GO:0051339 169 86 0,000 0,16020071 0,16313895 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,16190598 0,1648068 ! alcohol catabolic process GO:0046164 142 87 0,000 0,16190598 0,16473816 ! nucleosome assembly GO:0006334 126 87 0,000 0,16190598 0,16466957 ! cellular respiration GO:0045333 143 88 0,000 0,16360784 0,16633123 ! amine biosynthetic process GO:0009309 146 88 0,000 0,16360784 0,16626204 ! sensory perception of smell GO:0007608 117 88 0,000 0,16360784 0,16619291 ! chromatin assembly GO:0031497 128 88 0,000 0,16360784 0,16612384 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,16360784 0,16605482 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,16530629 0,167709 ! tube morphogenesis GO:0035239 194 89 0,000 0,16530629 0,16763938 ! regulation of neurological system process GO:0031644 175 89 0,000 0,16530629 0,16756982 ! response to inorganic substance GO:0010035 173 90 0,000 0,16700134 0,16921786 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,16700134 0,16914771 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,16700134 0,16907761 ! response to unfolded protein GO:0006986 139 90 0,000 0,16700134 0,16900757 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,16700134 0,16893758 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,16869299 0,17057822 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,16869299 0,17050765 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,17038126 0,17214285 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,17038126 0,17207169 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,17206614 0,17370148 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,17206614 0,17362973 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,17206614 0,17355805 ! vitamin metabolic process GO:0006766 153 93 0,000 0,17206614 0,17348642 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,17374765 0,17510954 ! female pregnancy GO:0007565 166 94 0,000 0,17374765 0,17503733 ! sterol metabolic process GO:0016125 166 94 0,000 0,17374765 0,17496518 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,17374765 0,17489309 ! regulation of defense response GO:0031347 171 95 0,000 0,1754258 0,17650956 ! nucleosome organization GO:0034728 143 95 0,000 0,1754258 0,1764369 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,1754258 0,17636429 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,1754258 0,17629174 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,1754258 0,17621925 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,1754258 0,17614682 ! sex differentiation GO:0007548 171 96 0,000 0,17710058 0,17775543 ! response to protein stimulus GO:0051789 158 96 0,000 0,17710058 0,17768243 ! regulation of T cell activation GO:0050863 175 96 0,000 0,17710058 0,17760949 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,17877201 0,17921215 ! transcription initiation GO:0006352 171 97 0,000 0,17877201 0,17913864 ! forebrain development GO:0030900 210 98 0,000 0,18044009 0,18073601 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,18044009 0,18066194 ! mRNA transport GO:0051028 185 100 0,000 0,18376623 0,18391679 ! positive regulation of immune response GO:0050778 175 100 0,000 0,18376623 0,18384148 ! hormone metabolic process GO:0042445 171 100 0,000 0,18376623 0,18376623