pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1021-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 4,000 1,768E-10 4,319E-07 ! lipid localization GO:0010876 32 14 3,000 5,876E-09 7,177E-06 GO:0019915|lipid storage, ! positive regulation of vasoconstriction GO:0045907 10 5 2,000 3,901E-08 3,177E-05 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 2,000 1,362E-07 8,32E-05 ! positive regulation of microtubule polymerization GO:0031116 15 7 2,000 1,362E-07 6,656E-05 ! gas homeostasis GO:0033483 14 8 2,000 2,177E-07 8,864E-05 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 2,000 2,177E-07 7,598E-05 ! regulation of microtubule polymerization GO:0031113 17 8 2,000 2,177E-07 6,648E-05 ! regulation of epithelial cell differentiation GO:0030856 18 9 2,000 3,262E-07 8,854E-05 ! tissue remodeling GO:0048771 78 37 3,000 3,772E-07 9,215E-05 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 4,211E-07 9,352E-05 ! negative regulation of MAPKKK cascade GO:0043409 20 10 2,000 4,655E-07 9,476E-05 ! response to insulin stimulus GO:0032868 98 47 3,000 1,007E-06 1,892E-04 ! gland morphogenesis GO:0022612 31 13 2,000 1,106E-06 1,929E-04 ! positive regulation of protein polymerization GO:0032273 27 14 2,000 1,405E-06 2,289E-04 ! regulation of vasodilation GO:0042312 27 15 2,000 1,755E-06 2,679E-04 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 2,000 2,617E-06 3,76E-04 ! positive regulation of protein complex assembly GO:0031334 34 18 2,000 3,136E-06 4,257E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 3,136E-06 4,033E-04 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 2,000 3,136E-06 3,831E-04 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 3,514E-06 4,088E-04 ! regulation of carbohydrate metabolic process GO:0006109 37 20 2,000 4,372E-06 4,855E-04 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of fatty acid metabolic process GO:0019217 45 20 2,000 4,372E-06 4,644E-04 ! regulation of vasoconstriction GO:0019229 40 21 2,000 5,095E-06 5,186E-04 ! inactivation of MAPK activity GO:0000188 45 22 2,000 5,892E-06 5,758E-04 ! positive regulation of cytoskeleton organization GO:0051495 52 24 2,000 7,726E-06 7,26E-04 ! membrane depolarization GO:0051899 45 24 2,000 7,726E-06 6,991E-04 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 2,000 7,726E-06 6,741E-04 ! protein oligomerization GO:0051259 149 79 3,000 8,162E-06 6,876E-04 ! vasculogenesis GO:0001570 49 25 2,000 8,77E-06 7,142E-04 ! regulation of smooth muscle contraction GO:0006940 48 26 2,000 9,903E-06 7,804E-04 ! regulation of cellular ketone metabolic process GO:0010565 51 26 2,000 9,903E-06 7,56E-04 ! regulation of blood coagulation GO:0030193 46 26 2,000 9,903E-06 7,331E-04 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 1,092E-05 7,847E-04 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 1,113E-05 7,767E-04 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 1,113E-05 7,552E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 1,387E-05 9,158E-04 ! negative regulation of protein kinase cascade GO:0010741 72 30 2,000 1,539E-05 9,896E-04 ! regulation of coagulation GO:0050818 52 30 2,000 1,539E-05 9,642E-04 ! negative regulation of multicellular organismal process GO:0051241 174 95 3,000 1,697E-05 1,036E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 2,000 1,702E-05 1,014E-03 ! cholesterol homeostasis GO:0042632 60 33 2,000 2,062E-05 1,199E-03 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 2,000 2,062E-05 1,171E-03 ! cholesterol transport GO:0030301 62 34 2,000 2,258E-05 1,254E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 2,258E-05 1,226E-03 ! sterol transport GO:0015918 63 35 2,000 2,467E-05 1,31E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,519E-05 1,309E-03 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 1,000 2,519E-05 1,282E-03 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! regulation of glycogen metabolic process GO:0070873 10 5 1,000 2,519E-05 1,256E-03 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,519E-05 1,231E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 2,519E-05 1,207E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 2,519E-05 1,183E-03 ! regulation of microtubule-based process GO:0032886 86 37 2,000 2,923E-05 1,347E-03 ! neutral lipid metabolic process GO:0006638 54 38 2,000 3,169E-05 1,434E-03 GO:0006639|acylglycerol metabolic process, ! mammary gland development GO:0030879 93 40 2,000 3,704E-05 1,645E-03 ! lipid homeostasis GO:0055088 75 40 2,000 3,704E-05 1,616E-03 ! glycerol ether metabolic process GO:0006662 57 40 2,000 3,704E-05 1,587E-03 ! cellular anion homeostasis GO:0030002 11 6 1,000 3,774E-05 1,59E-03 GO:0055081|anion homeostasis, ! organic ether metabolic process GO:0018904 59 42 2,000 4,294E-05 1,778E-03 ! vesicle fusion GO:0006906 20 7 1,000 5,279E-05 2,149E-03 ! male sex determination GO:0030238 15 7 1,000 5,279E-05 2,114E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 1,000 5,279E-05 2,08E-03 ! regulation of JAK-STAT cascade GO:0046425 76 48 2,000 6,425E-05 2,491E-03 ! protein homooligomerization GO:0051260 84 49 2,000 6,836E-05 2,609E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 7,031E-05 2,643E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 7,031E-05 2,603E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 7,031E-05 2,564E-03 ! vesicle organization GO:0016050 127 53 2,000 8,652E-05 3,108E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 9,03E-05 3,197E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 9,03E-05 3,152E-03 ! microtubule bundle formation GO:0001578 22 9 1,000 9,03E-05 3,107E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 9,03E-05 3,064E-03 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 9,03E-05 3,022E-03 ! regulation of muscle contraction GO:0006937 94 54 2,000 9,151E-05 3,021E-03 ! regulation of protein polymerization GO:0032271 117 55 2,000 9,668E-05 3,149E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 1,128E-04 3,625E-03 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 1,128E-04 3,578E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 1,128E-04 3,532E-03 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 1,000 1,128E-04 3,487E-03 ! regulation of fat cell differentiation GO:0045598 18 10 1,000 1,128E-04 3,444E-03 ! induction of an organ GO:0001759 17 10 1,000 1,128E-04 3,401E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,128E-04 3,36E-03 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of cell migration GO:0030335 137 58 2,000 1,133E-04 3,335E-03 ! positive regulation of organelle organization GO:0010638 108 58 2,000 1,133E-04 3,296E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,377E-04 3,957E-03 ! negative regulation of ossification GO:0030279 27 11 1,000 1,377E-04 3,911E-03 ! negative regulation of glucose import GO:0046325 18 11 1,000 1,377E-04 3,866E-03 GO:0010829|negative regulation of glucose transport, ! regulation of embryonic development GO:0045995 35 11 1,000 1,377E-04 3,822E-03 ! regulation of protein complex assembly GO:0043254 132 63 2,000 1,45E-04 3,981E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 1,52E-04 4,125E-03 ! positive regulation of cell motion GO:0051272 157 65 2,000 1,591E-04 4,272E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,65E-04 4,383E-03 ! virus-host interaction GO:0019048 30 12 1,000 1,65E-04 4,336E-03 ! developmental induction GO:0031128 22 12 1,000 1,65E-04 4,289E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 1,65E-04 4,244E-03 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 1,665E-04 4,238E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 1,9E-04 4,786E-03 ! organelle fusion GO:0048284 36 13 1,000 1,949E-04 4,857E-03 ! plasma membrane organization GO:0007009 27 13 1,000 1,949E-04 4,808E-03 ! Golgi organization GO:0007030 25 13 1,000 1,949E-04 4,76E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,949E-04 4,713E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! nucleoside triphosphate catabolic process GO:0009143 22 13 1,000 1,949E-04 4,667E-03 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 1,949E-04 4,622E-03 ! negative regulation of kinase activity GO:0033673 145 70 2,000 1,983E-04 4,658E-03 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 2,156E-04 5,016E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 1,000 2,271E-04 5,234E-03 ! negative regulation of transferase activity GO:0051348 155 74 2,000 2,338E-04 5,338E-03 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 2,618E-04 5,921E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,988E-04 6,698E-03 ! bone remodeling GO:0046849 28 16 1,000 2,988E-04 6,637E-03 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 2,988E-04 6,577E-03 ! response to hypoxia GO:0001666 178 81 2,000 3,053E-04 6,659E-03 ! regulation of peptidase activity GO:0052547 150 82 2,000 3,165E-04 6,842E-03 ! response to oxygen levels GO:0070482 183 83 2,000 3,28E-04 7,029E-03 ! cilium assembly GO:0042384 38 19 1,000 4,245E-04 9,019E-03 ! ossification GO:0001503 205 91 2,000 4,297E-04 9,051E-03 ! gland development GO:0048732 220 91 2,000 4,297E-04 8,973E-03 ! bone development GO:0060348 206 92 2,000 4,437E-04 9,187E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 4,58E-04 9,402E-03 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 4,712E-04 9,593E-03 ! regulation of glucose import GO:0046324 30 20 1,000 4,712E-04 9,514E-03 GO:0010827|regulation of glucose transport, ! regulation of membrane potential GO:0042391 179 94 2,000 4,726E-04 9,463E-03 ! lipid phosphorylation GO:0046834 43 21 1,000 5,203E-04 0,01033407 ! skeletal muscle tissue development GO:0007519 223 100 2,000 5,662E-04 0,01115498 GO:0060538|skeletal muscle organ development, ! positive regulation of DNA replication GO:0045740 44 23 1,000 6,255E-04 0,01222568 ! regulation of bone mineralization GO:0030500 54 23 1,000 6,255E-04 0,01212865 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 6,817E-04 0,01311356 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 6,817E-04 0,01301111 ! sex determination GO:0007530 48 24 1,000 6,817E-04 0,01291025 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 6,817E-04 0,01281094 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 6,817E-04 0,01271315 ! platelet activation GO:0030168 41 24 1,000 6,817E-04 0,01261684 ! interaction with host GO:0051701 66 25 1,000 7,402E-04 0,01359683 ! regulation of biomineral formation GO:0070167 56 25 1,000 7,402E-04 0,01349536 ! protein tetramerization GO:0051262 57 25 1,000 7,402E-04 0,0133954 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 8,011E-04 0,01439015 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 8,011E-04 0,01428511 GO:0045936|negative regulation of phosphate metabolic process, ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 9,298E-04 0,01646037 ! vesicle docking GO:0048278 55 28 1,000 9,298E-04 0,01634195 ! negative regulation of protein modification process GO:0031400 66 28 1,000 9,298E-04 0,01622522 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 9,298E-04 0,01611015 ! positive regulation of catabolic process GO:0009896 72 32 1,000 1,215E-03 0,02090414 ! cell fate specification GO:0001708 56 34 1,000 1,371E-03 0,02343 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 1,371E-03 0,02326729 ! membrane docking GO:0022406 69 35 1,000 1,453E-03 0,02448205 ! calcium-mediated signaling GO:0019722 67 35 1,000 1,453E-03 0,02431436 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 1,712E-03 0,02844441 ! carbohydrate homeostasis GO:0033500 59 39 1,000 1,802E-03 0,02974876 GO:0042593|glucose homeostasis, ! nucleotide catabolic process GO:0009166 70 39 1,000 1,802E-03 0,02954911 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 2,393E-03 0,0389743 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 2,499E-03 0,04043446 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 2,499E-03 0,04016844 ! cell growth GO:0016049 90 46 1,000 2,499E-03 0,0399059 ! positive regulation of cell cycle GO:0045787 96 48 1,000 2,718E-03 0,04312056 ! regulation of ossification GO:0030278 123 50 1,000 2,946E-03 0,04643104 ! positive regulation of growth GO:0045927 96 53 1,000 3,304E-03 0,05173578 ! activation of phospholipase C activity GO:0007202 110 54 1,000 3,427E-03 0,05332865 GO:0010863|positive regulation of phospholipase C activity, ! membrane fusion GO:0006944 122 54 1,000 3,427E-03 0,05299113 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 3,553E-03 0,05458889 ! response to UV GO:0009411 120 55 1,000 3,553E-03 0,05424771 ! regulation of DNA replication GO:0006275 105 56 1,000 3,681E-03 0,05585011 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 3,811E-03 0,05746474 ! heart morphogenesis GO:0003007 105 57 1,000 3,811E-03 0,0571122 ! regulation of bone remodeling GO:0046850 143 57 1,000 3,811E-03 0,05676395 ! regulation of phospholipase activity GO:0010517 113 57 1,000 3,811E-03 0,05641993 ! regulation of tissue remodeling GO:0034103 146 58 1,000 3,943E-03 0,05802335 ! positive regulation of lipase activity GO:0060193 115 58 1,000 3,943E-03 0,0576759 ! maintenance of location GO:0051235 124 58 1,000 3,943E-03 0,05733259 ! lipid modification GO:0030258 112 60 1,000 4,213E-03 0,06090228 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 4,351E-03 0,06253221 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 4,351E-03 0,06216652 ! viral reproductive process GO:0022415 132 62 1,000 4,492E-03 0,06379979 ! negative regulation of cell growth GO:0030308 142 67 1,000 5,225E-03 0,07378578 ! activation of MAPK activity GO:0000187 124 67 1,000 5,225E-03 0,07336172 ! viral reproduction GO:0016032 142 68 1,000 5,378E-03 0,07507591 ! regulation of lipase activity GO:0060191 137 68 1,000 5,378E-03 0,07464935 ! cell projection assembly GO:0030031 138 68 1,000 5,378E-03 0,0742276 ! negative regulation of cell size GO:0045792 144 69 1,000 5,533E-03 0,07593604 ! lung development GO:0030324 165 69 1,000 5,533E-03 0,07551181 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 5,533E-03 0,0750923 ! respiratory tube development GO:0030323 171 72 1,000 6,01E-03 0,08111243 ! respiratory system development GO:0060541 175 74 1,000 6,337E-03 0,08506848 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 6,844E-03 0,09137022 ! regulation of catabolic process GO:0009894 173 77 1,000 6,844E-03 0,09087364 ! blood coagulation GO:0007596 151 79 1,000 7,192E-03 0,09497565 GO:0050817|coagulation, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 7,548E-03 0,09913693 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 7,911E-03 0,10335583 GO:0045937|positive regulation of phosphate metabolic process, ! inorganic anion transport GO:0015698 156 83 1,000 7,911E-03 0,10280607 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 7,993E-03 0,10331697 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 7,993E-03 0,1027732 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 7,993E-03 0,10223512 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 7,993E-03 0,10170265 ! positive regulation of helicase activity GO:0051096 12 5 0,000 7,993E-03 0,10117569 ! neuron fate determination GO:0048664 7 5 0,000 7,993E-03 0,10065416 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,993E-03 0,10013799 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 7,993E-03 0,09962708 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 7,993E-03 0,09912136 ! polyol transport GO:0015791 12 5 0,000 7,993E-03 0,09862075 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 7,993E-03 0,09812517 ! response to superoxide GO:0000303 10 5 0,000 7,993E-03 0,09763454 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,993E-03 0,0971488 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 7,993E-03 0,09666786 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 7,993E-03 0,09619166 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 7,993E-03 0,09572014 ! female meiosis GO:0007143 10 5 0,000 7,993E-03 0,09525321 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 7,993E-03 0,09479082 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 7,993E-03 0,09433289 ! hypothalamus development GO:0021854 9 5 0,000 7,993E-03 0,09387936 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 7,993E-03 0,09343018 ! cobalt ion transport GO:0006824 11 5 0,000 7,993E-03 0,09298528 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 7,993E-03 0,09254459 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 7,993E-03 0,09210806 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 7,993E-03 0,09167562 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 7,993E-03 0,09124723 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 7,993E-03 0,09082283 ! embryonic camera-type eye development GO:0031076 12 5 0,000 7,993E-03 0,09040235 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 7,993E-03 0,08998575 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,993E-03 0,08957297 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 7,993E-03 0,08916396 ! transposition GO:0032196 9 5 0,000 7,993E-03 0,08875867 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 7,993E-03 0,08835705 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 7,993E-03 0,08795904 ! negative chemotaxis GO:0050919 16 5 0,000 7,993E-03 0,08756461 ! positive regulation of histone modification GO:0031058 6 5 0,000 7,993E-03 0,0871737 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 7,993E-03 0,08678626 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 7,993E-03 0,08640225 ! behavioral response to pain GO:0048266 10 5 0,000 7,993E-03 0,08602162 ! clathrin coat assembly GO:0048268 15 5 0,000 7,993E-03 0,08564433 ! Notch receptor processing GO:0007220 11 5 0,000 7,993E-03 0,08527034 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,993E-03 0,0848996 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 7,993E-03 0,08453207 ! micturition GO:0060073 9 5 0,000 7,993E-03 0,08416771 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 7,993E-03 0,08380647 ! copulation GO:0007620 9 5 0,000 7,993E-03 0,08344832 ! glial cell fate commitment GO:0021781 14 5 0,000 7,993E-03 0,08309323 ! protein maturation by protein folding GO:0022417 14 5 0,000 7,993E-03 0,08274114 ! bioluminescence GO:0008218 9 5 0,000 7,993E-03 0,08239202 ! spermidine metabolic process GO:0008216 7 5 0,000 7,993E-03 0,08204583 ! regulation of potassium ion transport GO:0043266 10 5 0,000 7,993E-03 0,08170254 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 7,993E-03 0,08136212 ! apoptotic cell clearance GO:0043277 23 5 0,000 7,993E-03 0,08102451 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 7,993E-03 0,0806897 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 7,993E-03 0,08035765 ! lipoprotein particle clearance GO:0034381 10 5 0,000 7,993E-03 0,08002831 ! grooming behavior GO:0007625 6 5 0,000 7,993E-03 0,07970166 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 7,993E-03 0,07937767 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 7,993E-03 0,07905631 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 7,993E-03 0,07873753 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,993E-03 0,07842132 ! response to protozoan GO:0001562 13 5 0,000 7,993E-03 0,07810763 ! lymph vessel development GO:0001945 10 5 0,000 7,993E-03 0,07779645 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 7,993E-03 0,07748773 ! endochondral ossification GO:0001958 17 5 0,000 7,993E-03 0,07718145 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 7,993E-03 0,07687759 ! single strand break repair GO:0000012 8 5 0,000 7,993E-03 0,07657611 ! parathyroid gland development GO:0060017 14 5 0,000 7,993E-03 0,07627698 ! anagen GO:0042640 7 5 0,000 7,993E-03 0,07598019 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 7,993E-03 0,07568569 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 7,993E-03 0,07539347 ! cytokine secretion GO:0050663 15 5 0,000 7,993E-03 0,07510349 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 7,993E-03 0,07481574 ! ceramide catabolic process GO:0046514 7 5 0,000 7,993E-03 0,07453018 ! skeletal myofibril assembly GO:0014866 12 5 0,000 7,993E-03 0,0742468 ! smooth muscle tissue development GO:0048745 32 5 0,000 7,993E-03 0,07396556 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 7,993E-03 0,07368644 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 7,993E-03 0,07340943 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 7,993E-03 0,07313449 ! cardiac muscle fiber development GO:0048739 12 5 0,000 7,993E-03 0,0728616 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 7,993E-03 0,07259074 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 7,993E-03 0,07232188 ! neutrophil mediated immunity GO:0002446 7 5 0,000 7,993E-03 0,07205501 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 7,993E-03 0,0717901 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 7,993E-03 0,07152714 ! glycine biosynthetic process GO:0006545 7 5 0,000 7,993E-03 0,07126609 ! microvillus organization GO:0032528 8 5 0,000 7,993E-03 0,07100694 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 7,993E-03 0,07074967 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 7,993E-03 0,07049425 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 7,993E-03 0,07024068 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 7,993E-03 0,06998892 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 7,993E-03 0,06973896 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 7,993E-03 0,06949078 ! polyol catabolic process GO:0046174 9 5 0,000 7,993E-03 0,06924435 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 7,993E-03 0,06899967 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 7,993E-03 0,06875672 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 7,993E-03 0,06851547 ! muscle cell migration GO:0014812 8 5 0,000 7,993E-03 0,0682759 ! mitochondrial fission GO:0000266 8 5 0,000 7,993E-03 0,06803801 ! sister chromatid cohesion GO:0007062 15 5 0,000 7,993E-03 0,06780176 ! response to tumor necrosis factor GO:0034612 10 5 0,000 7,993E-03 0,06756716 ! mRNA transcription GO:0009299 10 5 0,000 7,993E-03 0,06733417 ! nerve growth factor processing GO:0032455 9 5 0,000 7,993E-03 0,06710278 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 7,993E-03 0,06687297 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 7,993E-03 0,06664474 ! anaerobic glycolysis GO:0019642 6 5 0,000 7,993E-03 0,06641805 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 7,993E-03 0,06619291 ! monocyte activation GO:0042117 10 5 0,000 7,993E-03 0,06596928 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 7,993E-03 0,06574716 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 7,993E-03 0,06552654 ! response to food GO:0032094 6 5 0,000 7,993E-03 0,06530738 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 7,993E-03 0,06508969 ! positive regulation of transporter activity GO:0032411 8 5 0,000 7,993E-03 0,06487345 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,993E-03 0,06465864 ! forebrain neuron development GO:0021884 13 5 0,000 7,993E-03 0,06444524 ! lipoprotein catabolic process GO:0042159 11 5 0,000 7,993E-03 0,06423325 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 7,993E-03 0,06402265 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 7,993E-03 0,06381342 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 7,993E-03 0,06360556 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,993E-03 0,06339905 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 7,993E-03 0,06319388 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 7,993E-03 0,06299003 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 7,993E-03 0,06278749 ! lipid glycosylation GO:0030259 7 5 0,000 7,993E-03 0,06258624 ! nucleobase transport GO:0015851 6 5 0,000 7,993E-03 0,06238629 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,993E-03 0,0621876 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 7,993E-03 0,06199018 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 7,993E-03 0,06179401 ! basic amino acid transport GO:0015802 12 5 0,000 7,993E-03 0,06159908 ! cellular glucose homeostasis GO:0001678 6 5 0,000 7,993E-03 0,06140537 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 7,993E-03 0,06121288 ! actin nucleation GO:0045010 11 5 0,000 7,993E-03 0,06102159 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,993E-03 0,06083149 ! depurination GO:0045007 5 5 0,000 7,993E-03 0,06064257 ! depyrimidination GO:0045008 10 5 0,000 7,993E-03 0,06045482 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 7,993E-03 0,06026823 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,993E-03 0,06008279 ! G2/M transition checkpoint GO:0031576 8 5 0,000 7,993E-03 0,05989849 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 7,993E-03 0,05971531 ! zinc ion homeostasis GO:0055069 9 5 0,000 7,993E-03 0,05953326 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 7,993E-03 0,0593523 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 7,993E-03 0,05917245 ! forebrain morphogenesis GO:0048853 13 5 0,000 7,993E-03 0,05899368 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 7,993E-03 0,05881599 ! activated T cell proliferation GO:0050798 16 5 0,000 7,993E-03 0,05863936 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 7,993E-03 0,0584638 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 7,993E-03 0,05828928 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 7,993E-03 0,0581158 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,993E-03 0,05794335 ! gamma-delta T cell activation GO:0046629 6 5 0,000 7,993E-03 0,05777192 ! response to arsenic GO:0046685 11 5 0,000 7,993E-03 0,0576015 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 7,993E-03 0,05743208 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 7,993E-03 0,05726366 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 7,993E-03 0,05709622 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 7,993E-03 0,05692976 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 7,993E-03 0,05676427 ! response to mercury ion GO:0046689 8 5 0,000 7,993E-03 0,05659973 ! response to cadmium ion GO:0046686 7 5 0,000 7,993E-03 0,05643615 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 7,993E-03 0,05627351 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 7,993E-03 0,0561118 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 7,993E-03 0,05595103 ! bile acid biosynthetic process GO:0006699 7 5 0,000 7,993E-03 0,05579117 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 7,993E-03 0,05563222 ! ganglioside catabolic process GO:0006689 12 5 0,000 7,993E-03 0,05547417 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 7,993E-03 0,05531702 ! decidualization GO:0046697 11 5 0,000 7,993E-03 0,05516076 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 7,993E-03 0,05500537 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 7,993E-03 0,05485086 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 7,993E-03 0,05469722 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 7,993E-03 0,05454444 ! embryonic cleavage GO:0040016 6 5 0,000 7,993E-03 0,0543925 ! peroxisome fission GO:0016559 5 5 0,000 7,993E-03 0,05424141 ! histone demethylation GO:0016577 13 5 0,000 7,993E-03 0,05409116 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 7,993E-03 0,05394173 ! mitotic recombination GO:0006312 9 5 0,000 7,993E-03 0,05379313 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 7,993E-03 0,05364535 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 7,993E-03 0,05349838 ! metaphase plate congression GO:0051310 7 5 0,000 7,993E-03 0,05335221 ! regulation of sterol transport GO:0032371 7 5 0,000 7,993E-03 0,05320683 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 7,993E-03 0,05306225 ! enteric nervous system development GO:0048484 8 5 0,000 7,993E-03 0,05291845 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 7,993E-03 0,05277543 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 7,993E-03 0,05263317 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 7,993E-03 0,05249169 ! muscle cell proliferation GO:0033002 12 5 0,000 7,993E-03 0,05235096 ! skeletal muscle regeneration GO:0043403 8 5 0,000 7,993E-03 0,05221098 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 7,993E-03 0,05207175 ! B cell homeostasis GO:0001782 13 5 0,000 7,993E-03 0,05193327 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 7,993E-03 0,05179551 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 7,993E-03 0,05165849 ! metaphase GO:0051323 11 5 0,000 7,993E-03 0,05152218 ! melatonin biosynthetic process GO:0030187 7 5 0,000 7,993E-03 0,0513866 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 7,993E-03 0,05125173 ! cellular response to nutrient GO:0031670 8 5 0,000 7,993E-03 0,05111756 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 7,993E-03 0,05098409 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 7,993E-03 0,05085132 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 7,993E-03 0,05071924 ! regulation of hair follicle development GO:0051797 10 5 0,000 7,993E-03 0,05058784 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 7,993E-03 0,05045713 ! response to redox state GO:0051775 6 5 0,000 7,993E-03 0,05032708 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 7,993E-03 0,05019771 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 7,993E-03 0,05006899 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 7,993E-03 0,04994094 ! brown fat cell differentiation GO:0050873 7 5 0,000 7,993E-03 0,04981354 ! regulation of telomerase activity GO:0051972 7 5 0,000 7,993E-03 0,04968679 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,993E-03 0,04956068 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 7,993E-03 0,04943521 ! porphyrin catabolic process GO:0006787 12 5 0,000 7,993E-03 0,04931037 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 7,993E-03 0,04918617 ! striatum development GO:0021756 14 5 0,000 7,993E-03 0,04906258 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 7,993E-03 0,04893962 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 7,993E-03 0,04881727 ! glial cell migration GO:0008347 10 5 0,000 7,993E-03 0,04869553 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 7,993E-03 0,0485744 ! neural plate morphogenesis GO:0001839 7 5 0,000 7,993E-03 0,04845387 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 7,993E-03 0,04833393 ! somatic stem cell maintenance GO:0035019 15 5 0,000 7,993E-03 0,04821459 ! T cell activation during immune response GO:0002286 9 5 0,000 7,993E-03 0,04809583 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 7,993E-03 0,04797766 ! negative regulation of lipase activity GO:0060192 8 5 0,000 7,993E-03 0,04786007 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 7,993E-03 0,04774305 ! neuroprotection GO:0043526 8 5 0,000 7,993E-03 0,0476266 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 7,993E-03 0,04751072 ! regulation of sensory perception GO:0051931 8 5 0,000 7,993E-03 0,04739541 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 7,993E-03 0,04728065 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 7,993E-03 0,04716644 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 7,993E-03 0,04705279 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 7,993E-03 0,04693968 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 7,993E-03 0,04682712 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 7,993E-03 0,04671509 ! sequestering of calcium ion GO:0051208 7 5 0,000 7,993E-03 0,0466036 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 7,993E-03 0,04649264 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 7,993E-03 0,0463822 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 7,993E-03 0,04627229 ! spindle assembly GO:0051225 6 5 0,000 7,993E-03 0,0461629 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 7,993E-03 0,04605403 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 7,993E-03 0,04594567 ! protein palmitoylation GO:0018345 12 5 0,000 7,993E-03 0,04583781 ! drug metabolic process GO:0017144 7 5 0,000 7,993E-03 0,04573046 ! stem cell division GO:0017145 11 5 0,000 7,993E-03 0,04562362 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 7,993E-03 0,04551727 ! carnitine metabolic process GO:0009437 8 5 0,000 7,993E-03 0,04541141 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 7,993E-03 0,04530605 ! hemostasis GO:0007599 165 85 1,000 8,283E-03 0,04683932 ! negative regulation of transport GO:0051051 164 85 1,000 8,283E-03 0,04673115 ! negative regulation of growth GO:0045926 168 85 1,000 8,283E-03 0,04662347 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 9,584E-03 0,05382494 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 9,584E-03 0,05370149 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 9,584E-03 0,0535786 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 9,584E-03 0,05345627 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 9,584E-03 0,05333451 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 9,584E-03 0,05321329 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 9,584E-03 0,05309263 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 9,584E-03 0,05297251 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 9,584E-03 0,05285293 ! response to oxygen radical GO:0000305 11 6 0,000 9,584E-03 0,05273389 ! positive regulation of axon extension GO:0045773 13 6 0,000 9,584E-03 0,05261539 ! myoblast cell fate commitment GO:0048625 18 6 0,000 9,584E-03 0,05249742 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 9,584E-03 0,05237997 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 9,584E-03 0,05226305 ! regulation of interferon-beta production GO:0032648 8 6 0,000 9,584E-03 0,05214665 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 9,584E-03 0,05203077 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 9,584E-03 0,05191541 ! forebrain regionalization GO:0021871 9 6 0,000 9,584E-03 0,05180055 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 9,584E-03 0,0516862 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 9,584E-03 0,05157235 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 9,584E-03 0,05145901 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 9,584E-03 0,05134616 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 9,584E-03 0,0512338 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 9,584E-03 0,05112194 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 9,584E-03 0,05101056 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 9,584E-03 0,05089967 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 9,584E-03 0,05078926 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 9,584E-03 0,05067932 ! malate metabolic process GO:0006108 13 6 0,000 9,584E-03 0,05056987 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 9,584E-03 0,05046088 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 9,584E-03 0,05035236 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 9,584E-03 0,05024431 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 9,584E-03 0,05013672 ! protein refolding GO:0042026 15 6 0,000 9,584E-03 0,05002959 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 9,584E-03 0,04992292 ! opsonization GO:0008228 8 6 0,000 9,584E-03 0,0498167 ! mating behavior GO:0007617 7 6 0,000 9,584E-03 0,04971093 ! erythrocyte maturation GO:0043249 8 6 0,000 9,584E-03 0,04960561 ! embryonic hemopoiesis GO:0035162 16 6 0,000 9,584E-03 0,04950074 ! protein amino acid dealkylation GO:0008214 15 6 0,000 9,584E-03 0,0493963 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 9,584E-03 0,04929231 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 9,584E-03 0,04918876 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 9,584E-03 0,04908564 ! response to interferon-gamma GO:0034341 16 6 0,000 9,584E-03 0,04898295 ! toxin metabolic process GO:0009404 11 6 0,000 9,584E-03 0,04888068 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 9,584E-03 0,04877885 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 9,584E-03 0,04867744 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 9,584E-03 0,04857645 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 9,584E-03 0,04847588 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 9,584E-03 0,04837572 ! cGMP-mediated signaling GO:0019934 14 6 0,000 9,584E-03 0,04827598 ! dorsal spinal cord development GO:0021516 10 6 0,000 9,584E-03 0,04817664 ! activation of MAPKKK activity GO:0000185 12 6 0,000 9,584E-03 0,04807772 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 9,584E-03 0,0479792 ! thymic T cell selection GO:0045061 16 6 0,000 9,584E-03 0,04788108 ! sphingoid catabolic process GO:0046521 8 6 0,000 9,584E-03 0,04778336 ! protein lipoylation GO:0009249 10 6 0,000 9,584E-03 0,04768604 ! transepithelial chloride transport GO:0030321 12 6 0,000 9,584E-03 0,04758912 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 9,584E-03 0,04749259 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 9,584E-03 0,04739645 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 9,584E-03 0,0473007 ! glutamate catabolic process GO:0006538 12 6 0,000 9,584E-03 0,04720534 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 9,584E-03 0,04711036 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 9,584E-03 0,04701576 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 9,584E-03 0,04692154 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 9,584E-03 0,0468277 ! hyperosmotic response GO:0006972 10 6 0,000 9,584E-03 0,04673423 ! L-serine biosynthetic process GO:0006564 7 6 0,000 9,584E-03 0,04664113 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 9,584E-03 0,04654841 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 9,584E-03 0,04645605 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 9,584E-03 0,04636406 ! urea metabolic process GO:0019627 7 6 0,000 9,584E-03 0,04627243 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 9,584E-03 0,04618116 ! neutrophil activation GO:0042119 7 6 0,000 9,584E-03 0,04609025 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 9,584E-03 0,0459997 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 9,584E-03 0,04590951 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 9,584E-03 0,04581966 ! paraxial mesoderm development GO:0048339 16 6 0,000 9,584E-03 0,04573017 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 9,584E-03 0,04564103 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 9,584E-03 0,04555223 ! neuron apoptosis GO:0051402 15 6 0,000 9,584E-03 0,04546378 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 9,584E-03 0,04537567 ! T cell mediated immunity GO:0002456 17 6 0,000 9,584E-03 0,04528791 ! negative regulation of platelet activation GO:0010544 9 6 0,000 9,584E-03 0,04520048 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 9,584E-03 0,04511339 ! carnitine transport GO:0015879 10 6 0,000 9,584E-03 0,04502663 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,584E-03 0,04494021 ! positive regulation of exocytosis GO:0045921 11 6 0,000 9,584E-03 0,04485412 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 9,584E-03 0,04476835 ! early endosome to late endosome transport GO:0045022 16 6 0,000 9,584E-03 0,04468292 ! 5S class rRNA transcription GO:0042791 13 6 0,000 9,584E-03 0,04459781 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 9,584E-03 0,04451302 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 9,584E-03 0,04442855 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 9,584E-03 0,04434441 ! sodium ion homeostasis GO:0055078 12 6 0,000 9,584E-03 0,04426058 ! establishment of spindle localization GO:0051293 16 6 0,000 9,584E-03 0,04417707 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 9,584E-03 0,04409388 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 9,584E-03 0,04401099 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 9,584E-03 0,04392842 ! response to UV-C GO:0010225 14 6 0,000 9,584E-03 0,04384616 ! astrocyte development GO:0014002 16 6 0,000 9,584E-03 0,0437642 ! protein targeting to lysosome GO:0006622 12 6 0,000 9,584E-03 0,04368255 ! purine base biosynthetic process GO:0009113 17 6 0,000 9,584E-03 0,04360121 ! interaction with symbiont GO:0051702 14 6 0,000 9,584E-03 0,04352016 ! regulation of dendrite development GO:0050773 16 6 0,000 9,584E-03 0,04343942 ! peptidyl-arginine modification GO:0018195 13 6 0,000 9,584E-03 0,04335898 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 9,584E-03 0,04327883 ! response to copper ion GO:0046688 10 6 0,000 9,584E-03 0,04319898 ! response to exogenous dsRNA GO:0043330 13 6 0,000 9,584E-03 0,04311943 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 9,584E-03 0,04304016 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,584E-03 0,04296119 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 9,584E-03 0,04288251 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 9,584E-03 0,04280411 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 9,584E-03 0,042726 ! regulation of dopamine secretion GO:0014059 14 6 0,000 9,584E-03 0,04264817 ! nucleoside catabolic process GO:0009164 10 6 0,000 9,584E-03 0,04257063 ! hair follicle maturation GO:0048820 8 6 0,000 9,584E-03 0,04249337 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 9,584E-03 0,04241639 ! Schwann cell development GO:0014044 15 6 0,000 9,584E-03 0,04233969 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 9,584E-03 0,04226326 ! response to pheromone GO:0019236 6 6 0,000 9,584E-03 0,04218711 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 9,584E-03 0,04211124 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 9,584E-03 0,04203563 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 9,584E-03 0,0419603 ! base conversion or substitution editing GO:0016553 6 6 0,000 9,584E-03 0,04188524 ! subpallium development GO:0021544 15 6 0,000 9,584E-03 0,04181044 ! neural tube patterning GO:0021532 8 6 0,000 9,584E-03 0,04173591 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 9,584E-03 0,04166165 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 9,584E-03 0,04158765 ! maintenance of organ identity GO:0048496 9 6 0,000 9,584E-03 0,04151392 ! G2 phase GO:0051319 16 6 0,000 9,584E-03 0,04144044 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 9,584E-03 0,04136722 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 9,584E-03 0,04129426 ! oxygen homeostasis GO:0032364 10 6 0,000 9,584E-03 0,04122156 ! establishment of planar polarity GO:0001736 7 6 0,000 9,584E-03 0,04114912 ! regulation of mast cell activation GO:0033003 13 6 0,000 9,584E-03 0,04107693 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 9,584E-03 0,04100499 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 9,584E-03 0,0409333 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 9,584E-03 0,04086186 ! receptor internalization GO:0031623 11 6 0,000 9,584E-03 0,04079068 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 9,584E-03 0,04071974 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 9,584E-03 0,04064904 ! neutrophil homeostasis GO:0001780 11 6 0,000 9,584E-03 0,04057859 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,584E-03 0,04050839 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 9,584E-03 0,04043842 ! protein deubiquitination GO:0016579 16 6 0,000 9,584E-03 0,0403687 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 9,584E-03 0,04029922 ! protein destabilization GO:0031648 9 6 0,000 9,584E-03 0,04022998 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 9,584E-03 0,04016097 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 9,584E-03 0,04009221 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 9,584E-03 0,04002367 ! regulation of viral transcription GO:0046782 11 6 0,000 9,584E-03 0,03995537 ! progesterone metabolic process GO:0042448 12 6 0,000 9,584E-03 0,03988731 ! negative regulation of axon extension GO:0030517 24 6 0,000 9,584E-03 0,03981947 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 9,584E-03 0,03975186 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 9,584E-03 0,03968449 ! triglyceride catabolic process GO:0019433 10 6 0,000 9,584E-03 0,03961734 ! determination of adult lifespan GO:0008340 17 6 0,000 9,584E-03 0,03955042 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 9,584E-03 0,03948372 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 9,584E-03 0,03941725 ! neural plate development GO:0001840 9 6 0,000 9,584E-03 0,03935101 ! catecholamine transport GO:0051937 9 6 0,000 9,584E-03 0,03928498 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 9,584E-03 0,03921918 ! sensory cilium assembly GO:0035058 10 6 0,000 9,584E-03 0,03915359 ! organ or tissue specific immune response GO:0002251 8 6 0,000 9,584E-03 0,03908823 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 9,584E-03 0,03902308 ! maternal placenta development GO:0001893 12 6 0,000 9,584E-03 0,03895815 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 9,584E-03 0,03889344 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 9,584E-03 0,03882894 ! negative regulation of B cell activation GO:0050869 14 6 0,000 9,584E-03 0,03876465 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 9,584E-03 0,03870058 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 9,584E-03 0,03863671 ! positive regulation of coagulation GO:0050820 13 6 0,000 9,584E-03 0,03857306 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,0106706 0,04287544 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,01088178 0,04365219 ! tRNA transcription GO:0009304 17 7 0,000 0,0111726 0,04474535 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,0111726 0,04467212 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,0111726 0,04459912 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0111726 0,04452637 ! regulation of helicase activity GO:0051095 16 7 0,000 0,0111726 0,04445385 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,0111726 0,04438157 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,0111726 0,04430952 ! sleep GO:0030431 16 7 0,000 0,0111726 0,0442377 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0111726 0,04416612 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,0111726 0,04409477 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0111726 0,04402365 ! prostate gland development GO:0030850 14 7 0,000 0,0111726 0,04395276 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,0111726 0,0438821 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0111726 0,04381166 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0111726 0,04374145 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,0111726 0,04367146 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0111726 0,0436017 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,0111726 0,04353216 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,0111726 0,04346284 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0111726 0,04339374 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,0111726 0,04332486 ! glycolipid transport GO:0046836 11 7 0,000 0,0111726 0,0432562 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0111726 0,04318776 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,0111726 0,04311953 ! neuron adhesion GO:0007158 14 7 0,000 0,0111726 0,04305152 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,0111726 0,04298372 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0111726 0,04291614 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,0111726 0,04284876 ! mRNA stabilization GO:0048255 18 7 0,000 0,0111726 0,0427816 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,0111726 0,04271465 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,0111726 0,04264791 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,0111726 0,04258138 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,0111726 0,04251505 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,0111726 0,04244893 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,0111726 0,04238302 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0111726 0,04231731 ! lipoprotein transport GO:0042953 14 7 0,000 0,0111726 0,0422518 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,0111726 0,0421865 ! rhythmic behavior GO:0007622 17 7 0,000 0,0111726 0,04212139 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,0111726 0,04205649 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,0111726 0,04199179 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,0111726 0,04192729 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,0111726 0,04186298 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0111726 0,04179887 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,0111726 0,04173496 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0111726 0,04167124 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,0111726 0,04160772 ! mechanosensory behavior GO:0007638 16 7 0,000 0,0111726 0,04154439 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,0111726 0,04148125 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,0111726 0,04141831 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,0111726 0,04135555 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,0111726 0,04129299 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0111726 0,04123061 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0111726 0,04116842 ! spinal cord patterning GO:0021511 14 7 0,000 0,0111726 0,04110642 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,0111726 0,04104461 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,0111726 0,04098298 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0111726 0,04092153 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,0111726 0,04086027 ! adrenal gland development GO:0030325 17 7 0,000 0,0111726 0,0407992 ! cysteine metabolic process GO:0006534 13 7 0,000 0,0111726 0,0407383 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,0111726 0,04067759 ! ovulation GO:0030728 10 7 0,000 0,0111726 0,04061706 ! adenohypophysis development GO:0021984 11 7 0,000 0,0111726 0,04055671 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,0111726 0,04049653 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,0111726 0,04043654 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,0111726 0,04037672 ! microtubule nucleation GO:0007020 21 7 0,000 0,0111726 0,04031708 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0111726 0,04025762 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,0111726 0,04019833 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0111726 0,04013921 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,0111726 0,04008027 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,0111726 0,0400215 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0111726 0,0399629 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,0111726 0,03990448 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,0111726 0,03984622 ! galactose metabolic process GO:0006012 13 7 0,000 0,0111726 0,03978814 ! response to dietary excess GO:0002021 8 7 0,000 0,0111726 0,03973022 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0111726 0,03967248 ! intracellular pH reduction GO:0051452 13 7 0,000 0,0111726 0,0396149 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0111726 0,03955748 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,0111726 0,03950024 ! organ growth GO:0035265 15 7 0,000 0,0111726 0,03944316 ! nucleoside transport GO:0015858 11 7 0,000 0,0111726 0,03938624 ! nucleoside salvage GO:0043174 11 7 0,000 0,0111726 0,03932949 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,0111726 0,0392729 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,0111726 0,03921647 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,0111726 0,03916021 ! parturition GO:0007567 16 7 0,000 0,0111726 0,0391041 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,0111726 0,03904816 ! rRNA modification GO:0000154 14 7 0,000 0,0111726 0,03899238 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,0111726 0,03893675 ! spindle checkpoint GO:0031577 16 7 0,000 0,0111726 0,03888129 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,0111726 0,03882598 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,0111726 0,03877083 ! monocyte differentiation GO:0030224 16 7 0,000 0,0111726 0,03871583 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,0111726 0,038661 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0111726 0,03860631 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,0111726 0,03855178 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,0111726 0,03849741 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,0111726 0,03844319 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0111726 0,03838912 ! fibrinolysis GO:0042730 11 7 0,000 0,0111726 0,0383352 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,0111726 0,03828144 ! eating behavior GO:0042755 8 7 0,000 0,0111726 0,03822782 ! B cell lineage commitment GO:0002326 21 7 0,000 0,0111726 0,03817435 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0111726 0,03812104 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,0111726 0,03806787 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,0111726 0,03801485 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0111726 0,03796198 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,0111726 0,03790925 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0111726 0,03785668 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,0111726 0,03780424 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,0111726 0,03775195 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,0111726 0,03769981 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,0111726 0,03764781 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0111726 0,03759595 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,0111726 0,03754424 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0111726 0,03749267 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0111726 0,03744124 ! histone ubiquitination GO:0016574 9 7 0,000 0,0111726 0,03738995 ! regulation of meiosis GO:0040020 12 7 0,000 0,0111726 0,0373388 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,0111726 0,03728779 ! T cell lineage commitment GO:0002360 16 7 0,000 0,0111726 0,03723692 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,0111726 0,03718619 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0111726 0,0371356 ! membrane to membrane docking GO:0022614 14 7 0,000 0,0111726 0,03708514 ! transcription termination GO:0006353 14 7 0,000 0,0111726 0,03703482 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0111726 0,03698464 ! anaphase GO:0051322 18 7 0,000 0,0111726 0,03693459 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,0111726 0,03688468 ! axonal fasciculation GO:0007413 19 7 0,000 0,0111726 0,0368349 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,0111726 0,03678526 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,0111726 0,03673575 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,0111726 0,03668638 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,0111726 0,03663713 ! diuresis GO:0030146 12 7 0,000 0,0111726 0,03658802 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0111726 0,03653904 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0111726 0,03649019 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0111726 0,03644147 ! antibiotic transport GO:0042891 9 7 0,000 0,0111726 0,03639288 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0111726 0,03634443 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,0111726 0,03629609 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,0111726 0,03624789 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,0111726 0,03619982 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,0111726 0,03615187 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,0111726 0,03610405 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,0111726 0,03605636 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0111726 0,03600879 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0111726 0,03596135 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,0111726 0,03591403 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,0111726 0,03586684 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,0111726 0,03581977 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,0111726 0,03577282 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,0111726 0,035726 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,0111726 0,0356793 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,0111726 0,03563272 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,0111726 0,03558626 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,0111726 0,03553993 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0111726 0,03549371 ! muscle adaptation GO:0043500 13 7 0,000 0,0111726 0,03544761 ! embryonic heart tube development GO:0035050 14 7 0,000 0,0111726 0,03540164 ! retina homeostasis GO:0001895 12 7 0,000 0,0111726 0,03535578 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,0111726 0,03531004 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,0111726 0,03526442 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,0111726 0,03521892 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01275864 0,0401667 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01275864 0,04011501 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01275864 0,04006345 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01275864 0,04001202 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01275864 0,03996072 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01275864 0,03990956 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01275864 0,03985852 ! male meiosis GO:0007140 9 8 0,000 0,01275864 0,03980762 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01275864 0,03975684 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01275864 0,03970619 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01275864 0,03965568 ! meiotic prophase I GO:0007128 14 8 0,000 0,01275864 0,03960529 ! response to zinc ion GO:0010043 12 8 0,000 0,01275864 0,03955503 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01275864 0,0395049 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01275864 0,03945489 ! oligopeptide transport GO:0006857 16 8 0,000 0,01275864 0,03940501 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01275864 0,03935526 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01275864 0,03930563 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01275864 0,03925612 ! signal peptide processing GO:0006465 12 8 0,000 0,01275864 0,03920675 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01275864 0,03915749 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01275864 0,03910836 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01275864 0,03905935 ! succinate metabolic process GO:0006105 17 8 0,000 0,01275864 0,03901047 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01275864 0,0389617 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01275864 0,03891306 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01275864 0,03886454 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01275864 0,03881614 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01275864 0,03876786 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01275864 0,03871971 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01275864 0,03867167 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01275864 0,03862375 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01275864 0,03857594 ! reflex GO:0060004 17 8 0,000 0,01275864 0,03852826 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01275864 0,0384807 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01275864 0,03843325 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01275864 0,03838592 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01275864 0,0383387 ! pigment granule organization GO:0048753 17 8 0,000 0,01275864 0,0382916 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01275864 0,03824462 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01275864 0,03819775 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01275864 0,038151 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01275864 0,03810436 ! histidine catabolic process GO:0006548 10 8 0,000 0,01275864 0,03805783 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01275864 0,03801142 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01275864 0,03796512 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01275864 0,03791893 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01275864 0,03787286 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01275864 0,0378269 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01275864 0,03778105 ! melanin metabolic process GO:0006582 17 8 0,000 0,01275864 0,03773531 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01275864 0,03768968 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01275864 0,03764416 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01275864 0,03759875 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01275864 0,03755345 ! macrophage activation GO:0042116 13 8 0,000 0,01275864 0,03750826 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01275864 0,03746318 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01275864 0,0374182 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01275864 0,03737334 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01275864 0,03732858 ! purine salvage GO:0043101 12 8 0,000 0,01275864 0,03728393 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01275864 0,03723938 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01275864 0,03719494 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01275864 0,03715061 ! osteoblast development GO:0002076 17 8 0,000 0,01275864 0,03710638 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01275864 0,03706226 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01275864 0,03701825 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01275864 0,03697433 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01275864 0,03693052 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01275864 0,03688682 ! response to UV-B GO:0010224 17 8 0,000 0,01275864 0,03684322 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01275864 0,03679972 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01275864 0,03675632 ! intermediate filament organization GO:0045109 12 8 0,000 0,01275864 0,03671303 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01275864 0,03666984 ! cellular extravasation GO:0045123 13 8 0,000 0,01275864 0,03662675 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01275864 0,03658376 ! response to antibiotic GO:0046677 11 8 0,000 0,01275864 0,03654087 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01275864 0,03649808 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01275864 0,0364554 ! DNA topological change GO:0006265 12 8 0,000 0,01275864 0,03641281 ! response to tropane GO:0014073 15 8 0,000 0,01275864 0,03637032 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01275864 0,03632793 ! melanosome transport GO:0032402 13 8 0,000 0,01275864 0,03628564 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01275864 0,03624345 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01275864 0,03620135 ! mast cell activation GO:0045576 14 8 0,000 0,01275864 0,03615935 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01275864 0,03611745 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01275864 0,03607565 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01275864 0,03603395 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01275864 0,03599234 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01275864 0,03595082 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01275864 0,0359094 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01275864 0,03586808 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01275864 0,03582685 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01275864 0,03578572 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01275864 0,03574468 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01275864 0,03570374 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01275864 0,03566289 ! response to tumor cell GO:0002347 16 8 0,000 0,01275864 0,03562213 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01275864 0,03558146 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01275864 0,03554089 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01275864 0,03550041 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01275864 0,03546003 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01275864 0,03541973 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01275864 0,03537953 ! hormone catabolic process GO:0042447 17 8 0,000 0,01275864 0,03533941 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01275864 0,03529939 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01275864 0,03525946 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01275864 0,03521962 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01275864 0,03517987 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01275864 0,03514021 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01275864 0,03510063 ! adult feeding behavior GO:0008343 10 8 0,000 0,01275864 0,03506115 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01275864 0,03502176 ! ATP catabolic process GO:0006200 11 8 0,000 0,01275864 0,03498245 ! blastocyst growth GO:0001832 19 8 0,000 0,01275864 0,03494323 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01275864 0,0349041 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01275864 0,03486506 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01275864 0,0348261 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01275864 0,03478724 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01275864 0,03474845 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01275864 0,03470976 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01275864 0,03467115 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01275864 0,03463263 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01275864 0,03459419 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01275864 0,03455583 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01275864 0,03451757 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01275864 0,03447938 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01275864 0,03444129 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01275864 0,03440327 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01275864 0,03436534 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01275864 0,03432749 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01275864 0,03428973 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01275864 0,03425205 ! axon extension GO:0048675 16 9 0,000 0,01434218 0,03846098 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01434218 0,03841881 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01434218 0,03837673 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01434218 0,03833474 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01434218 0,03829285 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01434218 0,03825104 ! reproductive behavior GO:0019098 22 9 0,000 0,01434218 0,03820933 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01434218 0,03816771 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01434218 0,03812618 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01434218 0,03808474 ! UTP metabolic process GO:0046051 10 9 0,000 0,01434218 0,03804338 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01434218 0,03800212 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01434218 0,03796095 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01434218 0,03791987 ! artery development GO:0060840 25 9 0,000 0,01434218 0,03787887 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01434218 0,03783797 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01434218 0,03779715 ! equilibrioception GO:0050957 20 9 0,000 0,01434218 0,03775642 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01434218 0,03771578 ! chemosensory behavior GO:0007635 21 9 0,000 0,01434218 0,03767522 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01434218 0,03763475 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01434218 0,03759437 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01434218 0,03755408 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01434218 0,03751387 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01434218 0,03747375 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01434218 0,03743371 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01434218 0,03739376 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01434218 0,0373539 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01434218 0,03731412 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01434218 0,03727442 ! protein targeting to ER GO:0045047 25 9 0,000 0,01434218 0,03723481 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01434218 0,03719528 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01434218 0,03715584 ! T cell selection GO:0045058 27 9 0,000 0,01434218 0,03711648 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01434218 0,0370772 ! glycine catabolic process GO:0006546 15 9 0,000 0,01434218 0,03703801 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01434218 0,0369989 ! endosome organization GO:0007032 20 9 0,000 0,01434218 0,03695987 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01434218 0,03692092 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01434218 0,03688206 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01434218 0,03684328 ! mannose metabolic process GO:0006013 13 9 0,000 0,01434218 0,03680458 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01434218 0,03676596 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01434218 0,03672742 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01434218 0,03668896 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01434218 0,03665058 ! receptor clustering GO:0043113 20 9 0,000 0,01434218 0,03661228 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01434218 0,03657407 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01434218 0,03653593 ! retinol metabolic process GO:0042572 20 9 0,000 0,01434218 0,03649787 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01434218 0,03645989 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01434218 0,03642199 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01434218 0,03638417 ! macrophage differentiation GO:0030225 15 9 0,000 0,01434218 0,03634643 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01434218 0,03630876 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01434218 0,03627118 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01434218 0,03623367 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01434218 0,03619624 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01434218 0,03615888 ! response to amine stimulus GO:0014075 13 9 0,000 0,01434218 0,0361216 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01434218 0,0360844 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01434218 0,03604728 ! erythrocyte development GO:0048821 17 9 0,000 0,01434218 0,03601023 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01434218 0,03597326 ! renal water homeostasis GO:0003091 15 9 0,000 0,01434218 0,03593637 ! postreplication repair GO:0006301 25 9 0,000 0,01434218 0,03589955 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01434218 0,0358628 ! icosanoid secretion GO:0032309 15 9 0,000 0,01434218 0,03582613 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01434218 0,03578954 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01434218 0,03575302 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01434218 0,03571657 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01434218 0,0356802 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01434218 0,0356439 ! sterol catabolic process GO:0016127 14 9 0,000 0,01434218 0,03560768 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01434218 0,03557153 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01434218 0,03553545 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01434218 0,03549945 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01434218 0,03546352 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01434218 0,03542766 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01434218 0,03539188 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01434218 0,03535616 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01434218 0,03532052 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01434218 0,03528495 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01434218 0,03524945 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01434218 0,03521403 ! purine base metabolic process GO:0006144 25 9 0,000 0,01434218 0,03517867 ! pigment granule transport GO:0051904 17 9 0,000 0,01434218 0,03514339 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01434218 0,03510817 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01434218 0,03507303 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01434218 0,03503796 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01434218 0,03500295 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01434218 0,03496802 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01434218 0,03493316 ! mitochondrion localization GO:0051646 18 9 0,000 0,01434218 0,03489836 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01592323 0,03870692 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01592323 0,03866844 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01592323 0,03863004 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01592323 0,03859172 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01592323 0,03855347 ! associative learning GO:0008306 21 10 0,000 0,01592323 0,0385153 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01592323 0,0384772 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01592323 0,03843918 ! phosphate transport GO:0006817 24 10 0,000 0,01592323 0,03840124 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01592323 0,03836337 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01592323 0,03832557 ! CTP metabolic process GO:0046036 11 10 0,000 0,01592323 0,03828785 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01592323 0,0382502 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01592323 0,03821263 ! GTP metabolic process GO:0046039 11 10 0,000 0,01592323 0,03817513 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01592323 0,0381377 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01592323 0,03810035 ! social behavior GO:0035176 29 10 0,000 0,01592323 0,03806307 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01592323 0,03802586 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01592323 0,03798872 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01592323 0,03795166 ! androgen metabolic process GO:0008209 17 10 0,000 0,01592323 0,03791467 ! phospholipid efflux GO:0033700 19 10 0,000 0,01592323 0,03787775 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01592323 0,03784091 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01592323 0,03780413 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01592323 0,03776743 ! lung alveolus development GO:0048286 26 10 0,000 0,01592323 0,0377308 ! pathogenesis GO:0009405 17 10 0,000 0,01592323 0,03769424 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01592323 0,03765775 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01592323 0,03762133 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01592323 0,03758498 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01592323 0,0375487 ! endoderm development GO:0007492 18 10 0,000 0,01592323 0,03751249 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01592323 0,03747635 ! arginine catabolic process GO:0006527 17 10 0,000 0,01592323 0,03744028 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01592323 0,03740428 ! proline metabolic process GO:0006560 13 10 0,000 0,01592323 0,03736835 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01592323 0,03733249 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01592323 0,0372967 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01592323 0,03726097 ! V(D)J recombination GO:0033151 34 10 0,000 0,01592323 0,03722531 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01592323 0,03718973 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01592323 0,03715421 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01592323 0,03711875 ! B cell proliferation GO:0042100 19 10 0,000 0,01592323 0,03708337 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01592323 0,03704805 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01592323 0,0370128 ! multicellular organism growth GO:0035264 19 10 0,000 0,01592323 0,03697762 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01592323 0,0369425 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01592323 0,03690745 ! ruffle organization GO:0031529 17 10 0,000 0,01592323 0,03687247 ! epithelial cell development GO:0002064 21 10 0,000 0,01592323 0,03683755 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01592323 0,0368027 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01592323 0,03676791 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01592323 0,0367332 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01592323 0,03669854 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01592323 0,03666395 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01592323 0,03662943 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01592323 0,03659497 ! motor axon guidance GO:0008045 22 10 0,000 0,01592323 0,03656058 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01592323 0,03652625 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01592323 0,03649198 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01592323 0,03645778 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01592323 0,03642365 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01592323 0,03638957 ! segment specification GO:0007379 15 10 0,000 0,01592323 0,03635556 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01592323 0,03632162 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01592323 0,03628774 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01592323 0,03625392 ! response to dsRNA GO:0043331 23 10 0,000 0,01592323 0,03622016 ! DNA ligation GO:0006266 18 10 0,000 0,01592323 0,03618647 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01592323 0,03615284 ! melanosome localization GO:0032400 16 10 0,000 0,01592323 0,03611927 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01592323 0,03608576 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01592323 0,03605232 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01592323 0,03601894 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01592323 0,03598562 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01592323 0,03595236 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01592323 0,03591916 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01592323 0,03588603 ! protein sumoylation GO:0016925 17 10 0,000 0,01592323 0,03585295 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01592323 0,03581994 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01592323 0,03578699 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01592323 0,03575409 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01592323 0,03572126 ! salivary gland development GO:0007431 28 10 0,000 0,01592323 0,03568849 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01592323 0,03565578 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01592323 0,03562313 ! midbrain development GO:0030901 14 10 0,000 0,01592323 0,03559053 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01592323 0,035558 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01592323 0,03552553 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01592323 0,03549311 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01592323 0,03546076 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01592323 0,03542846 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01592323 0,03539623 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01592323 0,03536405 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01592323 0,03533193 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01592323 0,03529987 ! detection of calcium ion GO:0005513 24 10 0,000 0,01592323 0,03526786 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01592323 0,03523592 ! blastocyst formation GO:0001825 18 10 0,000 0,01592323 0,03520403 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01592323 0,0351722 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01592323 0,03514043 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01592323 0,03510871 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01592323 0,03507705 ! response to nicotine GO:0035094 20 10 0,000 0,01592323 0,03504545 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01592323 0,03501391 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01592323 0,03498242 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01750179 0,03841587 ! respiratory burst GO:0045730 17 11 0,000 0,01750179 0,03838139 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01750179 0,03834696 ! neuron fate specification GO:0048665 18 11 0,000 0,01750179 0,0383126 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01750179 0,0382783 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01750179 0,03824406 ! thyroid gland development GO:0030878 26 11 0,000 0,01750179 0,03820989 ! synapsis GO:0007129 14 11 0,000 0,01750179 0,03817577 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01750179 0,03814172 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01750179 0,03810772 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01750179 0,03807379 ! response to pain GO:0048265 27 11 0,000 0,01750179 0,03803991 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01750179 0,0380061 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01750179 0,03797235 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01750179 0,03793865 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01750179 0,03790502 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01750179 0,03787145 ! bone resorption GO:0045453 16 11 0,000 0,01750179 0,03783793 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01750179 0,03780448 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01750179 0,03777108 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01750179 0,03773774 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01750179 0,03770447 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01750179 0,03767125 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01750179 0,03763808 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01750179 0,03760498 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01750179 0,03757194 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01750179 0,03753895 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01750179 0,03750602 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01750179 0,03747315 ! UV protection GO:0009650 20 11 0,000 0,01750179 0,03744034 ! adult heart development GO:0007512 16 11 0,000 0,01750179 0,03740758 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01750179 0,03737488 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01750179 0,03734224 ! macroautophagy GO:0016236 19 11 0,000 0,01750179 0,03730965 ! temperature homeostasis GO:0001659 18 11 0,000 0,01750179 0,03727713 ! behavioral fear response GO:0001662 27 11 0,000 0,01750179 0,03724465 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01750179 0,03721224 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01750179 0,03717988 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01750179 0,03714758 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01750179 0,03711533 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01750179 0,03708314 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01750179 0,03705101 ! regulation of organ growth GO:0046620 14 11 0,000 0,01750179 0,03701893 ! pigment granule localization GO:0051875 20 11 0,000 0,01750179 0,03698691 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01750179 0,03695494 ! vasoconstriction GO:0042310 20 11 0,000 0,01750179 0,03692303 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01750179 0,03689117 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01750179 0,03685937 ! embryonic axis specification GO:0000578 19 11 0,000 0,01750179 0,03682762 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01750179 0,03679592 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01750179 0,03676429 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01750179 0,0367327 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01750179 0,03670117 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01750179 0,03666969 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01750179 0,03663827 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01750179 0,0366069 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01750179 0,03657559 ! prophase GO:0051324 17 11 0,000 0,01750179 0,03654433 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01750179 0,03651312 ! nucleosome positioning GO:0016584 15 11 0,000 0,01750179 0,03648197 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01750179 0,03645086 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01750179 0,03641982 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01750179 0,03638882 ! apical protein localization GO:0045176 18 11 0,000 0,01750179 0,03635788 ! acid secretion GO:0046717 20 11 0,000 0,01750179 0,03632699 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01750179 0,03629615 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01750179 0,03626536 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01750179 0,03623463 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01750179 0,03620395 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01750179 0,03617332 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01750179 0,03614274 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01750179 0,03611222 ! cholesterol efflux GO:0033344 21 11 0,000 0,01750179 0,03608174 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01750179 0,03605132 ! oocyte development GO:0048599 20 11 0,000 0,01750179 0,03602095 ! germ cell migration GO:0008354 26 11 0,000 0,01750179 0,03599063 ! embryonic gut development GO:0048566 19 11 0,000 0,01750179 0,03596036 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01750179 0,03593014 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01750179 0,03589997 ! activation of innate immune response GO:0002218 16 11 0,000 0,01750179 0,03586985 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01750179 0,03583979 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01750179 0,03580977 ! lysogeny GO:0030069 22 11 0,000 0,01750179 0,0357798 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01750179 0,03574989 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01750179 0,03572002 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01750179 0,0356902 ! nucleus localization GO:0051647 22 11 0,000 0,01750179 0,03566044 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01907785 0,03883933 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01907785 0,03880699 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01907785 0,03877471 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,01907785 0,03874247 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01907785 0,0387103 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01907785 0,03867817 ! protein complex disassembly GO:0043241 28 12 0,000 0,01907785 0,0386461 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01907785 0,03861408 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01907785 0,03858212 ! hippocampus development GO:0021766 29 12 0,000 0,01907785 0,0385502 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,01907785 0,03851834 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01907785 0,03848654 ! T cell proliferation GO:0042098 32 12 0,000 0,01907785 0,03845478 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01907785 0,03842308 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01907785 0,03839143 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01907785 0,03835983 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01907785 0,03832829 ! drug transport GO:0015893 16 12 0,000 0,01907785 0,03829679 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01907785 0,03826535 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01907785 0,03823396 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01907785 0,03820262 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01907785 0,03817133 ! focal adhesion formation GO:0048041 37 12 0,000 0,01907785 0,0381401 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01907785 0,03810891 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01907785 0,03807777 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01907785 0,03804669 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01907785 0,03801566 ! lipid digestion GO:0044241 21 12 0,000 0,01907785 0,03798468 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01907785 0,03795374 ! entry into host cell GO:0030260 34 12 0,000 0,01907785 0,03792286 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01907785 0,03789203 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01907785 0,03786125 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01907785 0,03783052 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01907785 0,03779983 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01907785 0,0377692 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01907785 0,03773862 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01907785 0,03770809 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01907785 0,0376776 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01907785 0,03764717 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01907785 0,03761678 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01907785 0,03758645 ! cranial nerve development GO:0021545 23 12 0,000 0,01907785 0,03755616 ! fucose catabolic process GO:0019317 25 12 0,000 0,01907785 0,03752592 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01907785 0,03749573 ! histone acetylation GO:0016573 27 12 0,000 0,01907785 0,03746559 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01907785 0,0374355 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01907785 0,03740545 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01907785 0,03737546 ! zymogen activation GO:0031638 18 12 0,000 0,01907785 0,03734551 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01907785 0,03731561 ! T cell homeostasis GO:0043029 28 12 0,000 0,01907785 0,03728576 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01907785 0,03725595 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01907785 0,0372262 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01907785 0,03719649 ! oocyte differentiation GO:0009994 21 12 0,000 0,01907785 0,03716682 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01907785 0,03713721 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01907785 0,03710764 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01907785 0,03707812 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01907785 0,03704865 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01907785 0,03701922 ! defense response to fungus GO:0050832 15 12 0,000 0,01907785 0,03698984 ! embryonic placenta development GO:0001892 21 12 0,000 0,01907785 0,0369605 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01907785 0,03693122 ! response to cold GO:0009409 17 12 0,000 0,01907785 0,03690198 ! establishment of cell polarity GO:0030010 21 12 0,000 0,01907785 0,03687278 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01907785 0,03684363 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02065144 0,03985107 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02065144 0,03981962 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02065144 0,03978822 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02065144 0,03975686 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02065144 0,03972556 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02065144 0,0396943 ! peroxisomal transport GO:0043574 28 13 0,000 0,02065144 0,0396631 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02065144 0,03963194 ! cartilage condensation GO:0001502 22 13 0,000 0,02065144 0,03960083 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02065144 0,03956977 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02065144 0,03953876 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02065144 0,0395078 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02065144 0,03947689 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02065144 0,03944602 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02065144 0,0394152 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02065144 0,03938443 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02065144 0,03935371 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02065144 0,03932304 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02065144 0,03929241 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02065144 0,03926184 ! methionine metabolic process GO:0006555 31 13 0,000 0,02065144 0,03923131 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02065144 0,03920082 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02065144 0,03917039 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02065144 0,03914 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02065144 0,03910966 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02065144 0,03907937 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02065144 0,03904912 ! exocrine system development GO:0035272 34 13 0,000 0,02065144 0,03901892 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02065144 0,03898876 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02065144 0,03895866 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02065144 0,0389286 ! L-glutamate transport GO:0015813 30 13 0,000 0,02065144 0,03889858 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02065144 0,03886861 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02065144 0,03883869 ! protein homotetramerization GO:0051289 24 13 0,000 0,02065144 0,03880882 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02065144 0,03877899 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02065144 0,0387492 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02065144 0,03871946 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02065144 0,03868977 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02065144 0,03866012 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02065144 0,03863052 ! histone methylation GO:0016571 29 13 0,000 0,02065144 0,03860096 ! chromatin silencing GO:0006342 29 13 0,000 0,02065144 0,03857145 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02065144 0,03854199 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02065144 0,03851257 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02065144 0,03848319 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02065144 0,03845386 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02065144 0,03842457 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02065144 0,03839533 ! spleen development GO:0048536 24 13 0,000 0,02065144 0,03836613 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02065144 0,03833698 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02065144 0,03830787 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02065144 0,0382788 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02065144 0,03824978 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02065144 0,0382208 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02065144 0,03819187 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02065144 0,03816298 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02065144 0,03813413 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02065144 0,03810533 ! insulin secretion GO:0030073 24 13 0,000 0,02065144 0,03807657 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02065144 0,03804786 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02065144 0,03801919 ! acrosome reaction GO:0007340 19 13 0,000 0,02065144 0,03799056 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02065144 0,03796197 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02065144 0,03793343 ! rRNA transcription GO:0009303 28 14 0,000 0,02222254 0,04078863 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02222254 0,04075801 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02222254 0,04072743 ! water transport GO:0006833 21 14 0,000 0,02222254 0,0406969 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02222254 0,04066642 ! non-recombinational repair GO:0000726 29 14 0,000 0,02222254 0,04063598 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02222254 0,04060558 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02222254 0,04057524 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02222254 0,04054493 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02222254 0,04051468 ! palate development GO:0060021 32 14 0,000 0,02222254 0,04048446 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02222254 0,0404543 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02222254 0,04042417 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02222254 0,0403941 ! arginine metabolic process GO:0006525 21 14 0,000 0,02222254 0,04036406 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02222254 0,04033408 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02222254 0,04030413 ! regulation of heart rate GO:0002027 25 14 0,000 0,02222254 0,04027423 ! fear response GO:0042596 34 14 0,000 0,02222254 0,04024438 ! organic alcohol transport GO:0015850 29 14 0,000 0,02222254 0,04021457 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02222254 0,0401848 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02222254 0,04015508 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02222254 0,0401254 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02222254 0,04009576 ! bone mineralization GO:0030282 18 14 0,000 0,02222254 0,04006617 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02222254 0,04003663 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02222254 0,04000712 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02222254 0,03997766 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02222254 0,03994825 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02222254 0,03991887 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02222254 0,03988954 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02222254 0,03986025 ! ribosome assembly GO:0042255 18 14 0,000 0,02222254 0,03983101 ! cerebellum development GO:0021549 23 14 0,000 0,02222254 0,03980181 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02222254 0,03977265 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02222254 0,03974353 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02222254 0,03971446 ! response to gamma radiation GO:0010332 30 14 0,000 0,02222254 0,03968543 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02222254 0,03965644 ! NADP metabolic process GO:0006739 24 14 0,000 0,02222254 0,03962749 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02222254 0,03959859 ! oxygen transport GO:0015671 22 14 0,000 0,02222254 0,03956973 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02222254 0,03954091 ! male genitalia development GO:0030539 26 14 0,000 0,02222254 0,03951213 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02222254 0,03948339 ! regulation of axon extension GO:0030516 43 14 0,000 0,02222254 0,0394547 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02222254 0,03942605 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02222254 0,03939743 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02379117 0,0421478 ! lactation GO:0007595 30 15 0,000 0,02379117 0,04211726 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,02379117 0,04208676 ! reproductive cellular process GO:0048610 22 15 0,000 0,02379117 0,04205631 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02379117 0,0420259 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02379117 0,04199554 ! superoxide anion generation GO:0042554 22 15 0,000 0,02379117 0,04196521 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02379117 0,04193494 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02379117 0,0419047 ! copper ion transport GO:0006825 22 15 0,000 0,02379117 0,04187451 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02379117 0,04184436 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02379117 0,04181426 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02379117 0,0417842 ! sulfate transport GO:0008272 27 15 0,000 0,02379117 0,04175418 ! response to cAMP GO:0051591 25 15 0,000 0,02379117 0,04172421 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02379117 0,04169428 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02379117 0,04166439 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02379117 0,04163454 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02379117 0,04160474 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02379117 0,04157498 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02379117 0,04154526 ! vesicle coating GO:0006901 38 15 0,000 0,02379117 0,04151559 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02379117 0,04148595 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02379117 0,04145636 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02379117 0,04142681 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02379117 0,04139731 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02379117 0,04136784 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02379117 0,04133842 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02379117 0,04130904 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02379117 0,0412797 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02379117 0,04125041 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02379117 0,04122115 ! histone deacetylation GO:0016575 24 15 0,000 0,02379117 0,04119194 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02379117 0,04116276 ! water homeostasis GO:0030104 28 15 0,000 0,02379117 0,04113363 ! cofactor transport GO:0051181 30 15 0,000 0,02379117 0,04110454 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02379117 0,04107549 ! muscle maintenance GO:0046716 26 15 0,000 0,02379117 0,04104648 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02379117 0,04101752 ! intestinal absorption GO:0050892 31 15 0,000 0,02379117 0,04098859 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02379117 0,0409597 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02379117 0,04093086 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02379117 0,04090206 ! cell killing GO:0001906 32 15 0,000 0,02379117 0,04087329 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02379117 0,04084457 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,02379117 0,04081589 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02379117 0,04078724 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02379117 0,04075864 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02379117 0,04073008 ! actin filament polymerization GO:0030041 27 15 0,000 0,02379117 0,04070156 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02379117 0,04067307 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02535732 0,04332024 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02535732 0,04328996 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02535732 0,04325973 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02535732 0,04322954 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02535732 0,0431994 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02535732 0,04316929 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,02535732 0,04313923 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02535732 0,04310921 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02535732 0,04307923 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02535732 0,0430493 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02535732 0,0430194 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,02535732 0,04298955 ! startle response GO:0001964 28 16 0,000 0,02535732 0,04295973 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02535732 0,04292996 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02535732 0,04290023 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02535732 0,04287054 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02535732 0,0428409 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02535732 0,04281129 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02535732 0,04278172 ! pituitary gland development GO:0021983 30 16 0,000 0,02535732 0,0427522 ! response to osmotic stress GO:0006970 27 16 0,000 0,02535732 0,04272271 ! lysosomal transport GO:0007041 31 16 0,000 0,02535732 0,04269327 ! fructose metabolic process GO:0006000 25 16 0,000 0,02535732 0,04266387 ! L-amino acid transport GO:0015807 33 16 0,000 0,02535732 0,04263451 ! stem cell development GO:0048864 46 16 0,000 0,02535732 0,04260518 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02535732 0,0425759 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02535732 0,04254666 ! intermediate filament-based process GO:0045103 36 16 0,000 0,02535732 0,04251746 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02535732 0,0424883 ! negative regulation of immune response GO:0050777 38 16 0,000 0,02535732 0,04245918 ! axon cargo transport GO:0008088 46 16 0,000 0,02535732 0,04243009 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02535732 0,04240105 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02535732 0,04237205 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,02535732 0,04234309 ! DNA replication initiation GO:0006270 28 16 0,000 0,02535732 0,04231416 ! neuron recognition GO:0008038 40 16 0,000 0,02535732 0,04228528 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02535732 0,04225644 ! tissue regeneration GO:0042246 27 16 0,000 0,02535732 0,04222763 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02535732 0,04219887 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02535732 0,04217014 ! biomineral formation GO:0031214 22 16 0,000 0,02535732 0,04214145 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02535732 0,04211281 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02535732 0,0420842 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02535732 0,04205563 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02535732 0,04202709 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02535732 0,0419986 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02535732 0,04197015 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02535732 0,04194173 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02535732 0,04191335 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02535732 0,04188501 ! peptide hormone processing GO:0016486 27 16 0,000 0,02535732 0,04185671 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02692101 0,04440785 ! metencephalon development GO:0022037 32 17 0,000 0,02692101 0,04437788 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02692101 0,04434796 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,02692101 0,04431807 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02692101 0,04428823 ! signal complex assembly GO:0007172 47 17 0,000 0,02692101 0,04425843 ! filopodium assembly GO:0046847 42 17 0,000 0,02692101 0,04422866 ! endothelial cell migration GO:0043542 31 17 0,000 0,02692101 0,04419894 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02692101 0,04416926 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02692101 0,04413961 ! glial cell development GO:0021782 28 17 0,000 0,02692101 0,04411001 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02692101 0,04408044 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02692101 0,04405092 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02692101 0,04402143 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02692101 0,04399199 ! myoblast differentiation GO:0045445 50 17 0,000 0,02692101 0,04396258 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02692101 0,04393321 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02692101 0,04390389 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02692101 0,0438746 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02692101 0,04384535 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02692101 0,04381614 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02692101 0,04378696 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02692101 0,04375783 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02692101 0,04372874 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02692101 0,04369968 ! membrane budding GO:0006900 42 17 0,000 0,02692101 0,04367066 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02692101 0,04364169 ! regulation of protein binding GO:0043393 33 17 0,000 0,02692101 0,04361275 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02692101 0,04358384 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02692101 0,04355498 ! genitalia development GO:0048806 32 17 0,000 0,02692101 0,04352616 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02692101 0,04349737 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02692101 0,04346862 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02692101 0,04343991 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02692101 0,04341124 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02692101 0,0433826 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02692101 0,043354 ! steroid catabolic process GO:0006706 34 17 0,000 0,02692101 0,04332544 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02692101 0,04329692 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02692101 0,04326843 ! gas transport GO:0015669 26 17 0,000 0,02692101 0,04323999 ! organic cation transport GO:0015695 32 17 0,000 0,02692101 0,04321158 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02692101 0,0431832 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02692101 0,04315487 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02692101 0,04312657 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02848223 0,0455977 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02848223 0,04556784 ! limbic system development GO:0021761 40 18 0,000 0,02848223 0,04553801 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02848223 0,04550823 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02848223 0,04547849 ! adult walking behavior GO:0007628 36 18 0,000 0,02848223 0,04544878 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02848223 0,04541912 ! heart looping GO:0001947 34 18 0,000 0,02848223 0,04538949 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02848223 0,0453599 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02848223 0,04533035 ! centrosome cycle GO:0007098 26 18 0,000 0,02848223 0,04530084 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02848223 0,04527136 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02848223 0,04524193 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02848223 0,04521253 ! glycine metabolic process GO:0006544 30 18 0,000 0,02848223 0,04518317 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02848223 0,04515385 ! response to retinoic acid GO:0032526 31 18 0,000 0,02848223 0,04512457 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02848223 0,04509532 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02848223 0,04506612 ! DNA integration GO:0015074 32 18 0,000 0,02848223 0,04503695 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02848223 0,04500782 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02848223 0,04497872 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02848223 0,04494967 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02848223 0,04492065 ! neural crest cell migration GO:0001755 41 18 0,000 0,02848223 0,04489167 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02848223 0,04486272 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02848223 0,04483382 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02848223 0,04480495 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02848223 0,04477612 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02848223 0,04474732 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02848223 0,04471856 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02848223 0,04468984 ! detection of bacterium GO:0016045 22 18 0,000 0,02848223 0,04466116 ! nerve development GO:0021675 34 18 0,000 0,02848223 0,04463251 ! defense response to virus GO:0051607 43 18 0,000 0,02848223 0,0446039 ! microspike assembly GO:0030035 46 18 0,000 0,02848223 0,04457533 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02848223 0,04454679 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,02848223 0,04451829 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03004099 0,04692464 ! positive regulation of translation GO:0045727 31 19 0,000 0,03004099 0,04689466 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03004099 0,04686471 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,03004099 0,0468348 ! neuron maturation GO:0042551 46 19 0,000 0,03004099 0,04680493 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03004099 0,0467751 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,03004099 0,04674531 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03004099 0,04671555 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03004099 0,04668584 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03004099 0,04665616 ! inositol metabolic process GO:0006020 33 19 0,000 0,03004099 0,04662652 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03004099 0,04659691 ! memory GO:0007613 34 19 0,000 0,03004099 0,04656734 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03004099 0,04653782 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03004099 0,04650832 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03004099 0,04647887 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03004099 0,04644945 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,03004099 0,04642007 ! cerebral cortex development GO:0021987 40 19 0,000 0,03004099 0,04639073 ! pigmentation during development GO:0048066 42 19 0,000 0,03004099 0,04636142 ! response to vitamin A GO:0033189 32 19 0,000 0,03004099 0,04633216 ! heme metabolic process GO:0042168 40 19 0,000 0,03004099 0,04630292 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03004099 0,04627373 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03004099 0,04624457 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03004099 0,04621545 ! response to fungus GO:0009620 26 19 0,000 0,03004099 0,04618637 ! peptide cross-linking GO:0018149 39 19 0,000 0,03004099 0,04615732 ! protein export from nucleus GO:0006611 40 19 0,000 0,03004099 0,04612831 ! heart process GO:0003015 32 19 0,000 0,03004099 0,04609933 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,03004099 0,04607039 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03004099 0,04604149 ! visual learning GO:0008542 38 19 0,000 0,03004099 0,04601262 ! cellular pigmentation GO:0033059 37 19 0,000 0,03004099 0,04598379 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03004099 0,045955 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03004099 0,04592624 ! vitamin transport GO:0051180 31 19 0,000 0,03004099 0,04589752 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03004099 0,04586883 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03004099 0,04584018 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,03004099 0,04581157 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03004099 0,04578299 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03004099 0,04575445 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03004099 0,04572594 ! protein secretion GO:0009306 45 20 0,000 0,03159729 0,04806487 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,03159729 0,04803496 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,03159729 0,04800509 ! positive regulation of ossification GO:0045778 50 20 0,000 0,03159729 0,04797525 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,03159729 0,04794546 ! skin development GO:0043588 42 20 0,000 0,03159729 0,04791569 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,03159729 0,04788597 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,03159729 0,04785628 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,03159729 0,04782663 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,03159729 0,04779702 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,03159729 0,04776744 ! response to vitamin GO:0033273 36 20 0,000 0,03159729 0,0477379 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,03159729 0,0477084 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,03159729 0,04767893 ! bile acid metabolic process GO:0008206 34 20 0,000 0,03159729 0,0476495 ! response to alkaloid GO:0043279 38 20 0,000 0,03159729 0,0476201 ! retinoid metabolic process GO:0001523 34 20 0,000 0,03159729 0,04759074 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,03159729 0,04756142 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,03159729 0,04753213 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,03159729 0,04750288 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,03159729 0,04747367 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,03159729 0,04744449 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,03159729 0,04741535 ! actin filament bundle formation GO:0051017 47 20 0,000 0,03159729 0,04738624 ! body fluid secretion GO:0007589 33 20 0,000 0,03159729 0,04735717 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,03159729 0,04732813 ! peptide secretion GO:0002790 38 20 0,000 0,03159729 0,04729913 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,03159729 0,04727017 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,03159729 0,04724124 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,03159729 0,04721234 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,03159729 0,04718349 ! cell-cell junction organization GO:0045216 43 20 0,000 0,03159729 0,04715466 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,03159729 0,04712588 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,03159729 0,04709712 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,03159729 0,0470684 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,03159729 0,04703972 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,03159729 0,04701107 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,03159729 0,04698246 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,03159729 0,04695388 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,03159729 0,04692534 ! negative regulation of translation GO:0017148 32 20 0,000 0,03159729 0,04689683 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,03159729 0,04686836 ! regulation of cell killing GO:0031341 46 21 0,000 0,03315114 0,04914335 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,03315114 0,04911355 ! hormone secretion GO:0046879 39 21 0,000 0,03315114 0,04908378 ! cAMP metabolic process GO:0046058 41 21 0,000 0,03315114 0,04905405 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,03315114 0,04902436 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,03315114 0,0489947 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,03315114 0,04896508 ! ovarian follicle development GO:0001541 39 21 0,000 0,03315114 0,04893549 ! smooth muscle contraction GO:0006939 48 21 0,000 0,03315114 0,04890594 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,03315114 0,04887643 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,03315114 0,04884695 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,03315114 0,0488175 ! plasma membrane fusion GO:0045026 33 21 0,000 0,03315114 0,0487881 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,03315114 0,04875872 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,03315114 0,04872939 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,03315114 0,04870008 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,03315114 0,04867082 ! diencephalon development GO:0021536 36 21 0,000 0,03315114 0,04864158 ! collagen fibril organization GO:0030199 62 21 0,000 0,03315114 0,04861239 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,03315114 0,04858323 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,03315114 0,0485541 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,03315114 0,04852501 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,03315114 0,04849595 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,03315114 0,04846693 ! collagen catabolic process GO:0030574 29 21 0,000 0,03315114 0,04843794 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,03315114 0,04840899 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,03315114 0,04838007 ! sperm-egg recognition GO:0035036 23 21 0,000 0,03315114 0,04835119 ! actin filament-based movement GO:0030048 47 21 0,000 0,03315114 0,04832234 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,03315114 0,04829352 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,03470254 0,05052343 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,03470254 0,05049333 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,03470254 0,05046328 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,03470254 0,05043326 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,03470254 0,05040328 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,03470254 0,05037333 ! microtubule-based transport GO:0010970 59 22 0,000 0,03470254 0,05034341 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,03470254 0,05031354 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,03470254 0,05028369 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,03470254 0,05025389 ! cellular response to starvation GO:0009267 37 22 0,000 0,03470254 0,05022412 ! vacuolar transport GO:0007034 41 22 0,000 0,03470254 0,05019438 ! central nervous system neuron development GO:0021954 47 22 0,000 0,03470254 0,05016468 ! fucose metabolic process GO:0006004 44 22 0,000 0,03470254 0,05013501 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,03470254 0,05010538 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,03470254 0,05007579 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,03470254 0,05004623 ! ureteric bud development GO:0001657 50 22 0,000 0,03470254 0,0500167 ! cell aging GO:0007569 48 22 0,000 0,03470254 0,04998721 ! stem cell differentiation GO:0048863 57 22 0,000 0,03470254 0,04995775 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,03470254 0,04992833 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,03470254 0,04989895 ! cytolysis GO:0019835 27 22 0,000 0,03470254 0,04986959 ! renal system process GO:0003014 42 22 0,000 0,03470254 0,04984028 ! vasodilation GO:0042311 40 22 0,000 0,03470254 0,04981099 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,03470254 0,04978174 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,03470254 0,04975253 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,03470254 0,04972335 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,03470254 0,0496942 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,03470254 0,04966509 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,03470254 0,04963601 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,03470254 0,04960697 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,03470254 0,04957796 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,03470254 0,04954898 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,03470254 0,04952004 ! sarcomere organization GO:0045214 32 22 0,000 0,03470254 0,04949113 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,03470254 0,04946226 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,03470254 0,04943342 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,03470254 0,04940461 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,03470254 0,04937583 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,03470254 0,04934709 ! gut development GO:0048565 44 22 0,000 0,03470254 0,04931839 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,03470254 0,04928971 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,03470254 0,04926107 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,03470254 0,04923247 ! protein stabilization GO:0050821 41 22 0,000 0,03470254 0,04920389 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,0362515 0,0513703 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,0362515 0,05134052 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,0362515 0,05131078 ! gluconeogenesis GO:0006094 38 23 0,000 0,0362515 0,05128107 ! glycerol metabolic process GO:0006071 40 23 0,000 0,0362515 0,05125139 ! viral genome replication GO:0019079 44 23 0,000 0,0362515 0,05122175 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,0362515 0,05119214 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,0362515 0,05116257 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,0362515 0,05113303 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,0362515 0,05110352 ! regeneration GO:0031099 42 23 0,000 0,0362515 0,05107405 ! axis specification GO:0009798 43 23 0,000 0,0362515 0,05104461 ! visual behavior GO:0007632 46 23 0,000 0,0362515 0,05101521 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,0362515 0,05098584 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,0362515 0,0509565 ! response to ethanol GO:0045471 47 23 0,000 0,0362515 0,0509272 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,0362515 0,05089793 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,0362515 0,0508687 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,0362515 0,0508395 ! peroxisome organization GO:0007031 43 23 0,000 0,0362515 0,05081033 ! lysosome organization GO:0007040 47 23 0,000 0,0362515 0,05078119 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,0362515 0,05075209 ! vesicle targeting GO:0006903 49 23 0,000 0,0362515 0,05072303 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,0362515 0,05069399 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,0362515 0,05066499 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,0362515 0,05063602 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,0362515 0,05060709 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,0362515 0,05057819 ! DNA modification GO:0006304 36 23 0,000 0,0362515 0,05054932 ! fatty acid transport GO:0015908 47 23 0,000 0,0362515 0,05052048 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,0362515 0,05049168 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,0362515 0,05046291 ! hormone transport GO:0009914 41 23 0,000 0,0362515 0,05043417 ! cell-cell recognition GO:0009988 28 23 0,000 0,0362515 0,05040547 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,0362515 0,05037679 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,0362515 0,05034815 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,0362515 0,05031955 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,03779801 0,05243642 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,03779801 0,05240666 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,03779801 0,05237693 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,03779801 0,05234724 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,03779801 0,05231758 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,03779801 0,05228796 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,03779801 0,05225837 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,03779801 0,05222881 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,03779801 0,05219928 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,03779801 0,05216979 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,03779801 0,05214034 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,03779801 0,05211091 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,03779801 0,05208152 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,03779801 0,05205216 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,03779801 0,05202284 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,03779801 0,05199354 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,03779801 0,05196428 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,03779801 0,05193506 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,03779801 0,05190586 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,03779801 0,0518767 ! pallium development GO:0021543 56 24 0,000 0,03779801 0,05184758 ! oogenesis GO:0048477 44 24 0,000 0,03779801 0,05181848 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,03779801 0,05178942 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,03779801 0,05176039 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,03779801 0,05173139 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,03779801 0,05170243 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,03779801 0,05167349 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,03779801 0,05164459 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,03779801 0,05161573 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,03779801 0,05158689 ! regulation of amine transport GO:0051952 41 24 0,000 0,03779801 0,05155809 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,03934208 0,05363432 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,03934208 0,05360441 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,03934208 0,05357453 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,03934208 0,05354468 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,03934208 0,05351487 ! leukocyte adhesion GO:0007159 55 25 0,000 0,03934208 0,05348509 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,03934208 0,05345534 ! phototransduction GO:0007602 37 25 0,000 0,03934208 0,05342563 ! keratinization GO:0031424 37 25 0,000 0,03934208 0,05339595 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,03934208 0,0533663 ! vacuole organization GO:0007033 49 25 0,000 0,03934208 0,05333669 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,03934208 0,0533071 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,03934208 0,05327755 ! receptor metabolic process GO:0043112 53 25 0,000 0,03934208 0,05324804 ! chromosome condensation GO:0030261 48 25 0,000 0,03934208 0,05321855 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,03934208 0,0531891 ! regulation of behavior GO:0050795 48 25 0,000 0,03934208 0,05315968 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,03934208 0,0531303 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,03934208 0,05310094 ! immunoglobulin production GO:0002377 62 25 0,000 0,03934208 0,05307162 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,03934208 0,05304233 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,03934208 0,05301308 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,03934208 0,05298385 ! liver development GO:0001889 55 25 0,000 0,03934208 0,05295466 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,04088372 0,05499941 ! myelination GO:0042552 50 26 0,000 0,04088372 0,05496914 ! initiation of viral infection GO:0019059 60 26 0,000 0,04088372 0,05493891 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,04088372 0,0549087 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,04088372 0,05487853 ! molting cycle process GO:0022404 52 26 0,000 0,04088372 0,0548484 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,04088372 0,05481829 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,04088372 0,05478822 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,04088372 0,05475819 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,04088372 0,05472818 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,04088372 0,05469821 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,04088372 0,05466827 ! digestive system process GO:0022600 49 26 0,000 0,04088372 0,05463837 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,04088372 0,05460849 ! osteoblast differentiation GO:0001649 63 26 0,000 0,04088372 0,05457865 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,04088372 0,05454884 ! neural crest cell development GO:0014032 59 26 0,000 0,04088372 0,05451907 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,04088372 0,05448932 ! negative regulation of cell development GO:0010721 83 26 0,000 0,04088372 0,05445961 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,04088372 0,05442994 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,04088372 0,05440029 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,04088372 0,05437068 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,04088372 0,05434109 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,04088372 0,05431155 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,04088372 0,05428203 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,04088372 0,05425254 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,04088372 0,05422309 ! blastocyst development GO:0001824 50 26 0,000 0,04088372 0,05419367 ! telomere organization GO:0032200 46 26 0,000 0,04088372 0,05416428 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,04088372 0,05413492 ! neural tube closure GO:0001843 58 26 0,000 0,04088372 0,0541056 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,04088372 0,0540763 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,04088372 0,05404704 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,04088372 0,05401781 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,04242293 0,0560212 ! embryonic pattern specification GO:0009880 49 27 0,000 0,04242293 0,05599093 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,04242293 0,0559607 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,04242293 0,0559305 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,04242293 0,05590033 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,04242293 0,0558702 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,04242293 0,0558401 ! iron ion transport GO:0006826 65 27 0,000 0,04242293 0,05581003 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,04242293 0,05577999 ! superoxide metabolic process GO:0006801 41 27 0,000 0,04242293 0,05574998 ! tube lumen formation GO:0035148 59 27 0,000 0,04242293 0,05572001 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,04242293 0,05569007 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,04242293 0,05566016 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,04242293 0,05563028 ! response to starvation GO:0042594 47 27 0,000 0,04242293 0,05560044 ! response to toxin GO:0009636 49 27 0,000 0,04242293 0,05557063 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,04242293 0,05554085 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,04242293 0,0555111 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,04242293 0,05548138 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,04242293 0,0554517 ! leukocyte proliferation GO:0070661 59 27 0,000 0,04242293 0,05542204 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,04242293 0,05539242 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,04395971 0,05736836 ! neuron fate commitment GO:0048663 52 28 0,000 0,04395971 0,05733774 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,04395971 0,05730714 ! protein amino acid acylation GO:0043543 59 28 0,000 0,04395971 0,05727658 ! circadian rhythm GO:0007623 56 28 0,000 0,04395971 0,05724604 ! dendrite development GO:0016358 67 28 0,000 0,04395971 0,05721555 ! fat cell differentiation GO:0045444 57 28 0,000 0,04395971 0,05718508 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,04395971 0,05715465 ! sperm motility GO:0030317 37 28 0,000 0,04395971 0,05712424 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,04395971 0,05709388 ! base-excision repair GO:0006284 41 28 0,000 0,04395971 0,05706354 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,04395971 0,05703323 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,04395971 0,05700296 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,04395971 0,05697272 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,04395971 0,05694251 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,04395971 0,05691234 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,04395971 0,05688219 ! glutathione metabolic process GO:0006749 42 28 0,000 0,04395971 0,05685208 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,04395971 0,056822 ! lipid oxidation GO:0034440 48 28 0,000 0,04395971 0,05679195 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,04395971 0,05676193 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,04395971 0,05673195 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,04549407 0,05868111 ! translational initiation GO:0006413 66 29 0,000 0,04549407 0,05865014 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,04549407 0,05861921 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,04549407 0,05858831 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,04549407 0,05855744 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,04549407 0,0585266 ! autophagy GO:0006914 47 29 0,000 0,04549407 0,0584958 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,04549407 0,05846503 ! primary neural tube formation GO:0014020 61 29 0,000 0,04549407 0,05843429 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,04549407 0,05840358 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,04549407 0,05837291 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,04549407 0,05834227 ! somitogenesis GO:0001756 52 29 0,000 0,04549407 0,05831166 ! synaptogenesis GO:0007416 46 29 0,000 0,04549407 0,05828108 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,04549407 0,05825053 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,04549407 0,05822002 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,04549407 0,05818954 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,04549407 0,05815909 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,04702601 0,06008606 ! phenol metabolic process GO:0018958 56 30 0,000 0,04702601 0,06005465 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,04702601 0,06002327 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,04702601 0,05999193 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,04702601 0,05996062 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,04702601 0,05992934 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,04702601 0,0598981 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,04702601 0,05986688 ! acute-phase response GO:0006953 50 30 0,000 0,04702601 0,0598357 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,04702601 0,05980455 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,04702601 0,05977344 ! myofibril assembly GO:0030239 50 30 0,000 0,04702601 0,05974235 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,04702601 0,0597113 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,04702601 0,05968028 ! cell fate determination GO:0001709 64 30 0,000 0,04702601 0,0596493 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,04702601 0,05961834 ! phospholipid transport GO:0015914 65 30 0,000 0,04702601 0,05958742 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,04702601 0,05955653 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,04702601 0,05952567 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,04702601 0,05949485 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,04702601 0,05946405 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,04702601 0,05943329 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,04702601 0,05940256 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,04855554 0,06130293 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,04855554 0,06127127 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,04855554 0,06123964 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,04855554 0,06120804 ! cell junction assembly GO:0034329 85 31 0,000 0,04855554 0,06117647 ! regulation of innate immune response GO:0045088 57 31 0,000 0,04855554 0,06114494 ! ovulation cycle process GO:0022602 55 31 0,000 0,04855554 0,06111343 ! peptide transport GO:0015833 60 31 0,000 0,04855554 0,06108196 ! male gonad development GO:0008584 56 31 0,000 0,04855554 0,06105053 ! iron ion homeostasis GO:0055072 60 31 0,000 0,04855554 0,06101912 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,04855554 0,06098775 ! detection of light stimulus GO:0009583 44 31 0,000 0,04855554 0,06095641 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,04855554 0,0609251 ! natural killer cell activation GO:0030101 50 31 0,000 0,04855554 0,06089383 ! ensheathment of neurons GO:0007272 64 31 0,000 0,04855554 0,06086258 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,04855554 0,06083137 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,04855554 0,06080019 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,04855554 0,06076904 ! eye morphogenesis GO:0048592 65 31 0,000 0,04855554 0,06073793 ! response to heat GO:0009408 54 31 0,000 0,04855554 0,06070684 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,04855554 0,06067579 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,05008265 0,0625521 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,05008265 0,06252014 ! collagen metabolic process GO:0032963 49 32 0,000 0,05008265 0,06248821 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,05008265 0,06245631 ! spindle organization GO:0007051 50 32 0,000 0,05008265 0,06242444 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,05008265 0,06239261 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,05008265 0,06236081 ! metanephros development GO:0001656 81 32 0,000 0,05008265 0,06232904 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,05008265 0,06229731 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,05008265 0,0622656 ! muscle cell development GO:0055001 52 32 0,000 0,05008265 0,06223393 ! mesoderm formation GO:0001707 73 32 0,000 0,05008265 0,06220229 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,05008265 0,06217069 ! ovulation cycle GO:0042698 57 32 0,000 0,05008265 0,06213911 ! peripheral nervous system development GO:0007422 68 32 0,000 0,05008265 0,06210757 ! BMP signaling pathway GO:0030509 71 32 0,000 0,05008265 0,06207606 ! hindbrain development GO:0030902 65 32 0,000 0,05008265 0,06204458 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,05008265 0,06201313 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,05008265 0,06198172 ! gene silencing GO:0016458 71 32 0,000 0,05008265 0,06195033 ! regulation of pH GO:0006885 56 33 0,000 0,05160735 0,06380403 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,05160735 0,06377176 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,05160735 0,06373952 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,05160735 0,06370731 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,05160735 0,06367513 ! response to ionizing radiation GO:0010212 74 33 0,000 0,05160735 0,06364299 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,05160735 0,06361088 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,05160735 0,0635788 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,05160735 0,06354675 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,05160735 0,06351474 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,05160735 0,06348276 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,05160735 0,06345081 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,05160735 0,06341889 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,05312965 0,06525678 ! glial cell differentiation GO:0010001 67 34 0,000 0,05312965 0,06522399 ! post-embryonic development GO:0009791 76 34 0,000 0,05312965 0,06519123 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,05312965 0,0651585 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,05312965 0,06512581 ! spliceosome assembly GO:0000245 75 34 0,000 0,05312965 0,06509315 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,05312965 0,06506052 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,05312965 0,06502793 ! formation of primary germ layer GO:0001704 76 34 0,000 0,05312965 0,06499536 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,05312965 0,06496283 ! adult locomotory behavior GO:0008344 62 34 0,000 0,05312965 0,06493033 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,05464955 0,06675443 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,05464955 0,06672107 ! negative regulation of secretion GO:0051048 68 35 0,000 0,05464955 0,06668774 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,05464955 0,06665444 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,05464955 0,06662118 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,05464955 0,06658796 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,05464955 0,06655476 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,05464955 0,0665216 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,05464955 0,06648847 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,05464955 0,06645538 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,05464955 0,06642231 ! ceramide metabolic process GO:0006672 72 35 0,000 0,05464955 0,06638929 ! telencephalon development GO:0021537 81 35 0,000 0,05464955 0,06635629 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,05464955 0,06632332 ! placenta development GO:0001890 53 35 0,000 0,05464955 0,06629039 ! vesicle localization GO:0051648 70 35 0,000 0,05464955 0,06625749 ! regulation of muscle development GO:0048634 82 36 0,000 0,05616705 0,06806355 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,05616705 0,0680298 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,05616705 0,06799609 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,05616705 0,06796241 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,05616705 0,06792877 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,05616705 0,06789516 ! positive regulation of cell development GO:0010720 85 36 0,000 0,05616705 0,06786158 ! protein targeting to membrane GO:0006612 75 36 0,000 0,05616705 0,06782803 ! regulation of proteolysis GO:0030162 77 36 0,000 0,05616705 0,06779452 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,05616705 0,06776104 ! aerobic respiration GO:0009060 56 36 0,000 0,05616705 0,0677276 ! cytokine production GO:0001816 68 36 0,000 0,05616705 0,06769418 ! embryonic organ development GO:0048568 67 36 0,000 0,05616705 0,0676608 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,05616705 0,06762746 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,05616705 0,06759414 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,05768216 0,06938332 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,05768216 0,06934917 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,05768216 0,06931506 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,05768216 0,06928098 ! sister chromatid segregation GO:0000819 65 37 0,000 0,05768216 0,06924694 ! odontogenesis GO:0042476 74 37 0,000 0,05768216 0,06921293 ! actomyosin structure organization GO:0031032 68 37 0,000 0,05768216 0,06917895 ! cell junction organization GO:0034330 96 37 0,000 0,05768216 0,069145 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,05768216 0,06911109 ! female gonad development GO:0008585 71 37 0,000 0,05768216 0,06907722 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,05768216 0,06904337 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,05768216 0,06900956 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,05768216 0,06897578 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,05919488 0,07075005 ! meiosis I GO:0007127 74 38 0,000 0,05919488 0,07071545 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,05919488 0,07068089 ! organic anion transport GO:0015711 82 38 0,000 0,05919488 0,07064636 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,05919488 0,07061186 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,05919488 0,0705774 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,05919488 0,07054297 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,05919488 0,07050858 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,05919488 0,07047422 ! regulation of protein stability GO:0031647 77 38 0,000 0,05919488 0,07043989 ! spermatid development GO:0007286 69 38 0,000 0,05919488 0,0704056 ! glycogen metabolic process GO:0005977 63 38 0,000 0,05919488 0,07037133 ! pigment metabolic process GO:0042440 87 38 0,000 0,05919488 0,07033711 ! neural tube formation GO:0001841 79 38 0,000 0,05919488 0,07030291 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,06070521 0,07206163 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,06070521 0,07202663 ! negative regulation of binding GO:0051100 71 39 0,000 0,06070521 0,07199167 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,06070521 0,07195674 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,06070521 0,07192184 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,06070521 0,07188698 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,06070521 0,07185215 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,06070521 0,07181735 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,06070521 0,07178259 ! glucan metabolic process GO:0044042 64 39 0,000 0,06070521 0,07174786 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,06221316 0,07349457 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,06221316 0,07345904 ! learning GO:0007612 82 40 0,000 0,06221316 0,07342356 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,06221316 0,0733881 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,06221316 0,07335268 ! mismatch repair GO:0006298 58 40 0,000 0,06221316 0,0733173 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,06221316 0,07328195 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,06221316 0,07324663 ! RNA export from nucleus GO:0006405 61 41 0,000 0,06371874 0,07498308 ! mRNA catabolic process GO:0006402 79 41 0,000 0,06371874 0,07494698 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,06371874 0,07491091 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,06371874 0,07487488 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,06371874 0,07483888 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,06371874 0,07480292 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,06371874 0,07476699 ! gliogenesis GO:0042063 91 41 0,000 0,06371874 0,0747311 ! feeding behavior GO:0007631 69 41 0,000 0,06371874 0,07469524 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,06371874 0,07465941 ! mesenchymal cell development GO:0014031 94 41 0,000 0,06371874 0,07462362 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,06371874 0,07458787 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,06371874 0,07455214 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,06371874 0,07451646 ! spermatid differentiation GO:0048515 73 41 0,000 0,06371874 0,0744808 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,06371874 0,07444518 ! RNA modification GO:0009451 64 41 0,000 0,06371874 0,0744096 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,06522194 0,07612861 ! ear morphogenesis GO:0042471 64 42 0,000 0,06522194 0,07609226 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,06522194 0,07605594 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,06522194 0,07601965 ! T cell differentiation GO:0030217 93 42 0,000 0,06522194 0,0759834 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,06522194 0,07594718 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,06522194 0,075911 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,06522194 0,07587485 ! regulation of protein secretion GO:0050708 77 42 0,000 0,06522194 0,07583874 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,06522194 0,07580266 ! cytokinesis GO:0000910 84 42 0,000 0,06522194 0,07576661 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,06522194 0,0757306 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,06672276 0,07743644 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,06672276 0,07739967 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,06672276 0,07736294 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,06672276 0,07732624 ! regulation of tube size GO:0035150 76 43 0,000 0,06672276 0,07728957 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,06672276 0,07725294 ! glucose transport GO:0015758 66 43 0,000 0,06672276 0,07721635 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,06672276 0,07717979 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,06672276 0,07714326 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,06672276 0,07710677 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,06672276 0,07707031 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,06672276 0,07703389 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,06672276 0,0769975 ! segmentation GO:0035282 78 43 0,000 0,06672276 0,07696115 ! ion transmembrane transport GO:0034220 79 43 0,000 0,06672276 0,07692483 ! neuron migration GO:0001764 85 43 0,000 0,06672276 0,07688854 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,06672276 0,07685229 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,06822122 0,07854121 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,06822122 0,07850421 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,06822122 0,07846725 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,06822122 0,07843033 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,06822122 0,07839344 ! hexose transport GO:0008645 68 44 0,000 0,06822122 0,07835658 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,06822122 0,07831976 ! striated muscle contraction GO:0006941 85 44 0,000 0,06822122 0,07828297 ! phagocytosis GO:0006909 105 44 0,000 0,06822122 0,07824622 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,06822122 0,0782095 ! double-strand break repair GO:0006302 85 44 0,000 0,06822122 0,07817282 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,06971732 0,0798497 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,06971732 0,07981228 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,06971732 0,0797749 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,06971732 0,07973755 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,06971732 0,07970024 ! biopolymer methylation GO:0043414 91 45 0,000 0,06971732 0,07966296 ! B cell differentiation GO:0030183 124 45 0,000 0,06971732 0,07962571 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,06971732 0,07958851 ! female gamete generation GO:0007292 71 45 0,000 0,06971732 0,07955133 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,06971732 0,07951419 ! polyol metabolic process GO:0019751 77 45 0,000 0,06971732 0,07947709 ! developmental growth GO:0048589 88 45 0,000 0,06971732 0,07944002 ! maintenance of location in cell GO:0051651 101 45 0,000 0,06971732 0,07940299 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,07121105 0,08106645 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,07121105 0,08102869 ! glycolysis GO:0006096 71 46 0,000 0,07121105 0,08099097 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,07121105 0,08095328 ! leukocyte migration GO:0050900 75 46 0,000 0,07121105 0,08091563 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,07121105 0,08087801 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,07121105 0,08084043 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,07121105 0,08080288 ! pigmentation GO:0043473 103 46 0,000 0,07121105 0,08076537 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,07121105 0,08072789 ! neural tube development GO:0021915 91 47 0,000 0,07270243 0,08238035 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,07270243 0,08234216 ! positive regulation of defense response GO:0031349 88 48 0,000 0,07419146 0,08398968 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,07419146 0,08395078 ! mitochondrial transport GO:0006839 94 48 0,000 0,07419146 0,08391191 ! cellular component disassembly GO:0022411 89 48 0,000 0,07419146 0,08387308 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,07419146 0,08383429 ! endosome transport GO:0016197 127 48 0,000 0,07419146 0,08379553 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,07419146 0,08375681 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,07419146 0,08371812 ! male sex differentiation GO:0046661 93 48 0,000 0,07419146 0,08367947 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,07419146 0,08364085 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,07419146 0,08360227 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,07419146 0,08356373 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,07419146 0,08352522 ! methylation GO:0032259 97 48 0,000 0,07419146 0,08348675 ! response to calcium ion GO:0051592 94 49 0,000 0,07567813 0,08512048 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,07567813 0,08508131 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,07567813 0,08504217 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,07567813 0,08500307 ! JNK cascade GO:0007254 106 49 0,000 0,07567813 0,08496401 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,07567813 0,08492498 ! regulation of action potential GO:0001508 102 50 0,000 0,07716247 0,08655092 ! regulation of ion transport GO:0043269 86 50 0,000 0,07716247 0,0865112 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,07716247 0,08647152 ! endocrine system development GO:0035270 109 50 0,000 0,07716247 0,08643187 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,07716247 0,08639226 ! activation of caspase activity GO:0006919 95 50 0,000 0,07716247 0,08635268 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,07716247 0,08631314 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,07716247 0,08627364 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,07716247 0,08623417 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,07716247 0,08619474 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,07716247 0,08615535 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,07864446 0,08776994 ! viral infectious cycle GO:0019058 104 51 0,000 0,07864446 0,08772986 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,07864446 0,08768982 ! peptide metabolic process GO:0006518 80 51 0,000 0,07864446 0,08764982 ! response to temperature stimulus GO:0009266 84 51 0,000 0,07864446 0,08760985 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,07864446 0,08756992 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,07864446 0,08753002 ! positive regulation of binding GO:0051099 88 52 0,000 0,08012411 0,08913624 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,08012411 0,08909567 ! Notch signaling pathway GO:0007219 111 52 0,000 0,08012411 0,08905514 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,08012411 0,08901464 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,08012411 0,08897418 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,08012411 0,08893375 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,08012411 0,08889337 ! excretion GO:0007588 87 52 0,000 0,08012411 0,08885302 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,08012411 0,0888127 ! histone modification GO:0016570 104 52 0,000 0,08012411 0,08877242 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,08012411 0,08873218 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,08012411 0,08869198 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,08012411 0,08865181 ! amino acid activation GO:0043038 98 52 0,000 0,08012411 0,08861168 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,08160142 0,09020465 ! inner ear development GO:0048839 89 53 0,000 0,08160142 0,09016385 ! chromatin remodeling GO:0006338 122 53 0,000 0,08160142 0,09012309 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,08160142 0,09008237 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,08160142 0,09004168 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,08160142 0,09000103 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,08160142 0,08996041 ! cartilage development GO:0051216 99 53 0,000 0,08160142 0,08991984 ! synapse organization GO:0050808 102 53 0,000 0,08160142 0,0898793 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,08307641 0,09146267 ! regulation of translational initiation GO:0006446 87 54 0,000 0,08307641 0,09142147 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,08307641 0,09138031 ! neuromuscular process GO:0050905 107 54 0,000 0,08307641 0,09133918 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,08307641 0,0912981 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,08307641 0,09125704 ! covalent chromatin modification GO:0016569 115 54 0,000 0,08307641 0,09121603 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,08307641 0,09117505 ! regulation of cell shape GO:0008360 142 54 0,000 0,08307641 0,09113411 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,08307641 0,09109321 ! RNA catabolic process GO:0006401 103 55 0,000 0,08454907 0,09266638 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,08454907 0,09262483 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,08454907 0,09258331 ! cell recognition GO:0008037 98 55 0,000 0,08454907 0,09254183 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,08454907 0,09250039 ! cell maturation GO:0048469 107 55 0,000 0,08454907 0,09245898 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,08454907 0,09241762 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,0860194 0,09398274 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,0860194 0,09394072 ! glucose catabolic process GO:0006007 88 56 0,000 0,0860194 0,09389875 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,0860194 0,09385681 ! RNA elongation GO:0006354 90 56 0,000 0,0860194 0,09381491 ! chloride transport GO:0006821 102 57 0,000 0,08748742 0,09537339 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,08748742 0,09533085 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,08748742 0,09528835 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,08748742 0,09524588 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,08748742 0,09520346 ! regulation of actin filament length GO:0030832 118 58 0,000 0,08895311 0,09675532 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,08895311 0,09671226 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,08895311 0,09666924 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,08895311 0,09662626 ! aging GO:0007568 112 58 0,000 0,08895311 0,09658331 ! gastrulation GO:0007369 122 58 0,000 0,08895311 0,09654041 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,08895311 0,09649754 ! nuclear export GO:0051168 110 59 0,000 0,0904165 0,0980415 ! establishment of organelle localization GO:0051656 122 59 0,000 0,0904165 0,09799801 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,09187757 0,09953743 ! DNA catabolic process GO:0006308 94 60 0,000 0,09187757 0,09949331 ! regulation of endocytosis GO:0030100 104 60 0,000 0,09187757 0,09944923 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,09187757 0,09940519 ! adult behavior GO:0030534 104 60 0,000 0,09187757 0,09936118 ! kidney development GO:0001822 133 60 0,000 0,09187757 0,09931722 ! positive regulation of secretion GO:0051047 110 61 0,000 0,09333634 0,10084949 ! regulation of cellular component size GO:0032535 125 61 0,000 0,09333634 0,1008049 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,09333634 0,10076036 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,09333634 0,10071585 ! regulation of heart contraction GO:0008016 123 61 0,000 0,09333634 0,10067139 ! camera-type eye development GO:0043010 126 61 0,000 0,09333634 0,10062696 ! proton transport GO:0015992 117 61 0,000 0,09333634 0,10058257 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,09479281 0,10210707 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,09479281 0,10206207 ! tRNA processing GO:0008033 102 62 0,000 0,09479281 0,10201711 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,09479281 0,10197219 ! regulation of mitosis GO:0007088 112 63 0,000 0,09624698 0,10349092 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,09624698 0,10344539 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,09624698 0,1033999 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,09624698 0,10335445 ! hydrogen transport GO:0006818 121 64 0,000 0,09769885 0,10486744 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,09769885 0,10482139 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,09769885 0,10477537 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,09914843 0,10628329 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,09914843 0,10623668 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,09914843 0,1061901 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,09914843 0,10614357 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,09914843 0,10609708 ! ear development GO:0043583 114 66 0,000 0,10059573 0,10759867 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,10059573 0,10755158 ! gonad development GO:0008406 115 66 0,000 0,10059573 0,10750453 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,10059573 0,10745753 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,10204074 0,10895346 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,10204074 0,10890586 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,10204074 0,10885831 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,10204074 0,10881079 ! secondary metabolic process GO:0019748 125 67 0,000 0,10204074 0,10876332 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,10204074 0,10871588 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,10348347 0,11020493 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,10348347 0,11015691 ! hexose catabolic process GO:0019320 113 68 0,000 0,10348347 0,11010893 ! extracellular matrix organization GO:0030198 146 68 0,000 0,10348347 0,110061 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,10348347 0,1100131 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,10348347 0,10996525 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,10348347 0,10991744 ! adaptive immune response GO:0002250 126 68 0,000 0,10348347 0,10986967 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,10348347 0,10982194 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,10492392 0,11130227 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,10492392 0,11125396 ! urogenital system development GO:0001655 149 69 0,000 0,10492392 0,1112057 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,10492392 0,11115747 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,10492392 0,11110929 ! developmental maturation GO:0021700 128 69 0,000 0,10492392 0,11106115 ! single fertilization GO:0007338 83 69 0,000 0,10492392 0,11101305 ! cell redox homeostasis GO:0045454 114 70 0,000 0,10636209 0,11248597 ! germ cell development GO:0007281 133 70 0,000 0,10636209 0,1124373 ! activation of immune response GO:0002253 120 70 0,000 0,10636209 0,11238867 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,10636209 0,11234008 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,107798 0,11380748 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,107798 0,11375832 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,107798 0,1137092 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,107798 0,11366013 ! appendage morphogenesis GO:0035107 150 72 0,000 0,10923164 0,11512205 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,10923164 0,1150724 ! actin filament organization GO:0007015 167 72 0,000 0,10923164 0,1150228 ! B cell activation GO:0042113 179 72 0,000 0,10923164 0,11497324 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,10923164 0,11492373 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,10923164 0,11487426 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,10923164 0,11482483 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,10923164 0,11477544 ! appendage development GO:0048736 151 73 0,000 0,11066302 0,11622947 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,11066302 0,11617952 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,11066302 0,11612962 ! regulation of immune effector process GO:0002697 156 73 0,000 0,11066302 0,11607976 ! acute inflammatory response GO:0002526 118 74 0,000 0,11209214 0,11752836 ! amino acid transport GO:0006865 148 74 0,000 0,11209214 0,11747794 ! regulation of caspase activity GO:0043281 136 74 0,000 0,11209214 0,11742757 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,11209214 0,11737723 ! organelle localization GO:0051640 155 74 0,000 0,11209214 0,11732694 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,113519 0,11876955 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,113519 0,11871871 ! reproductive structure development GO:0048608 131 75 0,000 0,113519 0,11866791 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,113519 0,11861715 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,113519 0,11856644 ! eye development GO:0001654 155 75 0,000 0,113519 0,11851577 ! axon guidance GO:0007411 162 75 0,000 0,113519 0,11846515 ! rhythmic process GO:0048511 142 75 0,000 0,113519 0,11841456 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,1149436 0,11984943 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,1149436 0,1197983 ! learning or memory GO:0007611 161 76 0,000 0,1149436 0,11974722 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,1149436 0,11969617 ! regulation of blood pressure GO:0008217 134 76 0,000 0,1149436 0,11964517 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,1149436 0,11959422 ! amine catabolic process GO:0009310 136 77 0,000 0,11636596 0,12102258 ! neurotransmitter transport GO:0006836 142 77 0,000 0,11636596 0,12097108 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,11636596 0,12091963 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,11636596 0,12086822 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,11636596 0,12081685 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,11636596 0,12076553 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,11636596 0,12071425 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,11778608 0,12213556 ! antigen processing and presentation GO:0019882 117 78 0,000 0,11778608 0,12208374 ! fertilization GO:0009566 99 78 0,000 0,11778608 0,12203197 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,11778608 0,12198024 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,11920395 0,12339629 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,11920395 0,12334402 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,11920395 0,1232918 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,11920395 0,12323963 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,11920395 0,1231875 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,12061958 0,12459773 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,12061958 0,12454507 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,12061958 0,12449245 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,12061958 0,12443988 ! meiosis GO:0007126 143 81 0,000 0,12203297 0,12584489 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,12203297 0,1257918 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,12203297 0,12573874 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,12344414 0,12713914 ! protein import into nucleus GO:0006606 174 82 0,000 0,12344414 0,12708556 ! meiotic cell cycle GO:0051321 144 82 0,000 0,12344414 0,12703203 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,12485307 0,12842781 ! exocytosis GO:0006887 153 83 0,000 0,12485307 0,12837376 ! response to drug GO:0042493 149 83 0,000 0,12485307 0,12831976 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,12485307 0,12826579 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,12485307 0,12821188 ! nuclear import GO:0051170 177 83 0,000 0,12485307 0,12815801 ! response to metal ion GO:0010038 158 84 0,000 0,12625978 0,12954752 ! T cell activation GO:0042110 189 84 0,000 0,12625978 0,12949314 ! response to nutrient GO:0007584 135 84 0,000 0,12625978 0,1294388 ! digestion GO:0007586 130 84 0,000 0,12625978 0,1293845 ! regulation of ligase activity GO:0051340 147 84 0,000 0,12625978 0,12933025 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,12766427 0,13071409 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,12766427 0,13065933 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,12766427 0,13060462 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,12766427 0,13054995 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,12906655 0,13192869 ! regulation of lyase activity GO:0051339 169 86 0,000 0,12906655 0,13187351 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,12906655 0,13181838 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,1304666 0,13319261 ! mitochondrion organization GO:0007005 159 87 0,000 0,1304666 0,13313697 ! alcohol catabolic process GO:0046164 142 87 0,000 0,1304666 0,13308138 ! nucleosome assembly GO:0006334 126 87 0,000 0,1304666 0,13302584 ! regulation of protein transport GO:0051223 165 87 0,000 0,1304666 0,13297034 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,13186445 0,13433897 ! amine biosynthetic process GO:0009309 146 88 0,000 0,13186445 0,13428297 ! sensory perception of smell GO:0007608 117 88 0,000 0,13186445 0,13422702 ! chromatin assembly GO:0031497 128 88 0,000 0,13186445 0,13417111 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,13186445 0,13411526 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,13326009 0,13547831 ! regulation of DNA binding GO:0051101 167 89 0,000 0,13326009 0,13542196 ! tube morphogenesis GO:0035239 194 89 0,000 0,13326009 0,13536565 ! cellular defense response GO:0006968 123 89 0,000 0,13326009 0,13530939 ! protein localization in nucleus GO:0034504 192 89 0,000 0,13326009 0,13525317 ! regulation of neurological system process GO:0031644 175 89 0,000 0,13326009 0,13519701 ! response to inorganic substance GO:0010035 173 90 0,000 0,13465352 0,13655398 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,13465352 0,13649732 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,13465352 0,13644071 ! response to unfolded protein GO:0006986 139 90 0,000 0,13465352 0,13638414 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,13465352 0,13632762 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,13604475 0,13767909 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,13604475 0,13762208 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,13743379 0,13896968 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,13743379 0,13891218 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,13882063 0,14025591 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,13882063 0,14019793 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,13882063 0,14014 ! vitamin metabolic process GO:0006766 153 93 0,000 0,13882063 0,14008211 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,14020528 0,14142093 ! female pregnancy GO:0007565 166 94 0,000 0,14020528 0,14136256 ! sterol metabolic process GO:0016125 166 94 0,000 0,14020528 0,14130424 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,14020528 0,14124597 ! regulation of defense response GO:0031347 171 95 0,000 0,14158774 0,1425799 ! nucleosome organization GO:0034728 143 95 0,000 0,14158774 0,14252116 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,14158774 0,14246246 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,14158774 0,14240381 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,14158774 0,1423452 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,14158774 0,14228665 ! sex differentiation GO:0007548 171 96 0,000 0,14296802 0,14361467 ! response to protein stimulus GO:0051789 158 96 0,000 0,14296802 0,14355564 ! regulation of T cell activation GO:0050863 175 96 0,000 0,14296802 0,14349666 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,14434612 0,14482035 ! transcription initiation GO:0006352 171 97 0,000 0,14434612 0,1447609 ! regulation of protein localization GO:0032880 188 97 0,000 0,14434612 0,1447015 ! leukocyte differentiation GO:0002521 232 98 0,000 0,14572204 0,14602089 ! forebrain development GO:0030900 210 98 0,000 0,14572204 0,14596102 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,14572204 0,1459012 ! mRNA transport GO:0051028 185 100 0,000 0,14846736 0,14858901 ! positive regulation of immune response GO:0050778 175 100 0,000 0,14846736 0,14852816 ! hormone metabolic process GO:0042445 171 100 0,000 0,14846736 0,14846736