pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1017-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 3,000 4,911E-08 1,2E-04 ! positive regulation of protein polymerization GO:0032273 27 14 2,000 1,815E-06 2,216E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 3,317E-06 2,701E-03 ! signal complex assembly GO:0007172 47 17 2,000 3,377E-06 2,063E-03 ! positive regulation of protein complex assembly GO:0031334 34 18 2,000 4,048E-06 1,978E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 4,048E-06 1,648E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 5,245E-06 1,831E-03 ! positive regulation of cytoskeleton organization GO:0051495 52 24 2,000 9,965E-06 3,043E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 1,435E-05 3,894E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 1,605E-05 3,921E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 1,788E-05 3,971E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,984E-05 6,074E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,984E-05 5,607E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 2,984E-05 5,206E-03 ! negative regulation of T cell mediated immunity GO:0002710 15 5 1,000 2,984E-05 4,859E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! protein insertion into membrane GO:0051205 17 5 1,000 2,984E-05 4,556E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 2,984E-05 4,288E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 4,082E-05 5,54E-03 ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 4,47E-05 5,748E-03 ! myoblast cell fate commitment GO:0048625 18 6 1,000 4,47E-05 5,46E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 6,251E-05 7,272E-03 ! vesicle fusion GO:0006906 20 7 1,000 6,251E-05 6,942E-03 ! male sex determination GO:0030238 15 7 1,000 6,251E-05 6,64E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 1,000 6,251E-05 6,363E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 6,251E-05 6,109E-03 ! cell growth GO:0016049 90 46 2,000 7,272E-05 6,833E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 7,758E-05 7,02E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 8,326E-05 7,264E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 8,326E-05 7,014E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 8,326E-05 6,78E-03 ! gas homeostasis GO:0033483 14 8 1,000 8,326E-05 6,561E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 8,326E-05 6,356E-03 ! lymph node development GO:0048535 11 8 1,000 8,326E-05 6,164E-03 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 1,000 8,326E-05 5,982E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 8,326E-05 5,811E-03 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 8,326E-05 5,65E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,069E-04 7,06E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 1,069E-04 6,874E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 1,069E-04 6,698E-03 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 20 9 1,000 1,069E-04 6,53E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,069E-04 6,371E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 1,069E-04 6,22E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 1,000 1,069E-04 6,075E-03 GO:0002820|negative regulation of adaptive immune response, ! regulation of protein polymerization GO:0032271 117 55 2,000 1,243E-04 6,9E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 1,335E-04 7,248E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 1,335E-04 7,09E-03 ! induction of an organ GO:0001759 17 10 1,000 1,335E-04 6,94E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,335E-04 6,795E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,335E-04 6,656E-03 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of immune effector process GO:0002698 23 10 1,000 1,335E-04 6,523E-03 ! positive regulation of organelle organization GO:0010638 108 58 2,000 1,456E-04 6,976E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,63E-04 7,657E-03 ! regulation of embryonic development GO:0045995 35 11 1,000 1,63E-04 7,513E-03 ! regulation of protein complex assembly GO:0043254 132 63 2,000 1,863E-04 8,426E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 1,952E-04 8,669E-03 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 1,952E-04 8,515E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,954E-04 8,373E-03 ! virus-host interaction GO:0019048 30 12 1,000 1,954E-04 8,229E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,954E-04 8,09E-03 ! focal adhesion formation GO:0048041 37 12 1,000 1,954E-04 7,955E-03 ! developmental induction GO:0031128 22 12 1,000 1,954E-04 7,824E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 1,000 1,954E-04 7,698E-03 ! localization within membrane GO:0051668 26 12 1,000 1,954E-04 7,576E-03 ! organelle fusion GO:0048284 36 13 1,000 2,306E-04 8,804E-03 ! plasma membrane organization GO:0007009 27 13 1,000 2,306E-04 8,668E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,306E-04 8,537E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,306E-04 8,409E-03 ! gland morphogenesis GO:0022612 31 13 1,000 2,306E-04 8,286E-03 ! positive regulation of T cell activation GO:0050870 124 68 2,000 2,336E-04 8,271E-03 ! lipid localization GO:0010876 32 14 1,000 2,688E-04 9,38E-03 GO:0019915|lipid storage, ! regulation of vasodilation GO:0042312 27 15 1,000 3,098E-04 0,01065866 ! regulation of T cell mediated immunity GO:0002709 36 15 1,000 3,098E-04 0,01051062 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 1,000 3,098E-04 0,01036664 ! cell-matrix adhesion GO:0007160 181 76 2,000 3,245E-04 0,01071145 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 3,502E-04 0,01140864 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,536E-04 0,01136713 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 3,536E-04 0,01121951 ! pituitary gland development GO:0021983 30 16 1,000 3,536E-04 0,01107567 ! negative regulation of immune response GO:0050777 38 16 1,000 3,536E-04 0,01093547 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 3,536E-04 0,01079878 ! protein oligomerization GO:0051259 149 79 2,000 3,636E-04 0,01096693 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 4,003E-04 0,0119267 ! myoblast differentiation GO:0045445 50 17 1,000 4,003E-04 0,011783 ! cell-substrate adhesion GO:0031589 189 82 2,000 4,057E-04 0,01179918 ! T cell activation GO:0042110 189 84 2,000 4,354E-04 0,01251462 ! cell-substrate junction assembly GO:0007044 56 18 1,000 4,499E-04 0,01277909 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 4,499E-04 0,0126322 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 4,508E-04 0,01251471 ! positive regulation of cell activation GO:0050867 161 86 2,000 4,665E-04 0,01280547 GO:0002696|positive regulation of leukocyte activation, ! gland development GO:0048732 220 91 2,000 5,504E-04 0,01493926 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 5,574E-04 0,01496384 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 5,574E-04 0,01480119 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 5,574E-04 0,01464204 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 5,574E-04 0,01448627 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 1,000 5,574E-04 0,01433378 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 5,864E-04 0,01492322 ! regulation of cell killing GO:0031341 46 21 1,000 6,154E-04 0,01549853 ! lipid phosphorylation GO:0046834 43 21 1,000 6,154E-04 0,01534038 ! regulation of vasoconstriction GO:0019229 40 21 1,000 6,154E-04 0,01518542 ! diencephalon development GO:0021536 36 21 1,000 6,154E-04 0,01503357 ! regulation of T cell activation GO:0050863 175 96 2,000 6,433E-04 0,01555997 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 6,63E-04 0,01587947 ! hindlimb morphogenesis GO:0035137 47 22 1,000 6,762E-04 0,01603724 ! inactivation of MAPK activity GO:0000188 45 22 1,000 6,762E-04 0,01588304 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 6,762E-04 0,01573177 ! skeletal muscle tissue development GO:0007519 223 100 2,000 7,244E-04 0,01669596 GO:0060538|skeletal muscle organ development, ! positive regulation of DNA replication GO:0045740 44 23 1,000 7,397E-04 0,01688899 ! regulation of DNA recombination GO:0000018 51 23 1,000 7,397E-04 0,01673261 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 7,397E-04 0,0165791 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 8,061E-04 0,01790176 ! membrane depolarization GO:0051899 45 24 1,000 8,061E-04 0,01774048 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 8,061E-04 0,01758208 ! sex determination GO:0007530 48 24 1,000 8,061E-04 0,01742649 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 8,061E-04 0,01727362 ! platelet activation GO:0030168 41 24 1,000 8,061E-04 0,01712342 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 8,061E-04 0,0169758 ! vasculogenesis GO:0001570 49 25 1,000 8,752E-04 0,01827372 ! interaction with host GO:0051701 66 25 1,000 8,752E-04 0,01811885 ! protein tetramerization GO:0051262 57 25 1,000 8,752E-04 0,0179666 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 9,47E-04 0,01927995 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 9,47E-04 0,01912061 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 9,47E-04 0,01896389 ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 9,47E-04 0,01880971 ! regulation of blood coagulation GO:0030193 46 26 1,000 9,47E-04 0,01865802 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 1,022E-03 0,01996702 ! cellular response to oxidative stress GO:0034599 43 27 1,000 1,022E-03 0,01980855 ! vesicle docking GO:0048278 55 28 1,000 1,099E-03 0,02114057 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 1,099E-03 0,02097541 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 1,099E-03 0,02081281 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 1,262E-03 0,02371371 ! regulation of coagulation GO:0050818 52 30 1,000 1,262E-03 0,02353269 ! cell junction assembly GO:0034329 85 31 1,000 1,347E-03 0,02493706 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 1,347E-03 0,02474956 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 1,436E-03 0,02617314 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 1,436E-03 0,02597926 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 1,436E-03 0,02578824 ! positive regulation of catabolic process GO:0009896 72 32 1,000 1,436E-03 0,0256 ! cholesterol homeostasis GO:0042632 60 33 1,000 1,527E-03 0,0270238 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 1,527E-03 0,02682939 ! cholesterol transport GO:0030301 62 34 1,000 1,62E-03 0,02827087 ! cell fate specification GO:0001708 56 34 1,000 1,62E-03 0,02807037 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 1,62E-03 0,02787269 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 1,62E-03 0,02767778 ! membrane docking GO:0022406 69 35 1,000 1,716E-03 0,02911868 ! sterol transport GO:0015918 63 35 1,000 1,716E-03 0,02891786 ! calcium-mediated signaling GO:0019722 67 35 1,000 1,716E-03 0,0287198 ! cell junction organization GO:0034330 96 37 1,000 1,917E-03 0,03185664 ! tissue remodeling GO:0048771 78 37 1,000 1,917E-03 0,0316414 ! regulation of microtubule-based process GO:0032886 86 37 1,000 1,917E-03 0,03142904 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 2,021E-03 0,032917 ! neutral lipid metabolic process GO:0006638 54 38 1,000 2,021E-03 0,032699 GO:0006639|acylglycerol metabolic process, ! carbohydrate homeostasis GO:0033500 59 39 1,000 2,128E-03 0,0342014 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 1,000 2,128E-03 0,03397786 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 2,128E-03 0,03375722 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 93 40 1,000 2,237E-03 0,03526511 ! lipid homeostasis GO:0055088 75 40 1,000 2,237E-03 0,03503905 ! glycerol ether metabolic process GO:0006662 57 40 1,000 2,237E-03 0,03481587 ! organic ether metabolic process GO:0018904 59 42 1,000 2,464E-03 0,03810262 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 2,464E-03 0,03786298 ! T cell differentiation GO:0030217 93 42 1,000 2,464E-03 0,03762634 ! regulation of leukocyte mediated immunity GO:0002703 84 42 1,000 2,464E-03 0,03739264 ! regulation of T cell differentiation GO:0045580 78 42 1,000 2,464E-03 0,03716182 ! regulation of T cell proliferation GO:0042129 80 43 1,000 2,582E-03 0,0386921 ! response to reactive oxygen species GO:0000302 75 44 1,000 2,701E-03 0,0402423 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 2,824E-03 0,04181193 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 2,824E-03 0,04156005 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 2,949E-03 0,04314061 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 2,949E-03 0,04288382 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 2,949E-03 0,04263007 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 2,949E-03 0,04237931 ! positive regulation of protein transport GO:0051222 80 46 1,000 2,949E-03 0,04213148 ! positive regulation of cell cycle GO:0045787 96 48 1,000 3,207E-03 0,0455481 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 3,207E-03 0,04528482 ! regulation of adaptive immune response GO:0002819 92 48 1,000 3,207E-03 0,04502456 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 3,34E-03 0,04662003 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 3,34E-03 0,04635515 ! protein homooligomerization GO:0051260 84 49 1,000 3,34E-03 0,04609325 ! endocrine system development GO:0035270 109 50 1,000 3,475E-03 0,04769064 ! negative regulation of immune system process GO:0002683 101 51 1,000 3,613E-03 0,04930466 ! positive regulation of growth GO:0045927 96 53 1,000 3,896E-03 0,05287316 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 3,896E-03 0,05258105 ! vesicle organization GO:0016050 127 53 1,000 3,896E-03 0,05229214 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 3,896E-03 0,05200639 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 1,000 3,896E-03 0,05172375 ! regulation of muscle contraction GO:0006937 94 54 1,000 4,041E-03 0,05336303 ! membrane fusion GO:0006944 122 54 1,000 4,041E-03 0,05307613 ! activation of phospholipase C activity GO:0007202 110 54 1,000 4,041E-03 0,0527923 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 4,189E-03 0,05443211 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 4,189E-03 0,05414411 ! response to UV GO:0009411 120 55 1,000 4,189E-03 0,05385914 ! skeletal muscle fiber development GO:0048741 130 56 1,000 4,339E-03 0,05549937 ! regulation of DNA replication GO:0006275 105 56 1,000 4,339E-03 0,05521031 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 4,492E-03 0,05685785 ! muscle fiber development GO:0048747 131 57 1,000 4,492E-03 0,05656477 ! heart morphogenesis GO:0003007 105 57 1,000 4,492E-03 0,05627469 ! regulation of intracellular transport GO:0032386 108 57 1,000 4,492E-03 0,05598757 ! regulation of phospholipase activity GO:0010517 113 57 1,000 4,492E-03 0,05570337 ! regulation of actin filament length GO:0030832 118 58 1,000 4,647E-03 0,05733723 ! positive regulation of lipase activity GO:0060193 115 58 1,000 4,647E-03 0,0570491 ! lipid modification GO:0030258 112 60 1,000 4,965E-03 0,06064583 ! regulation of cellular component size GO:0032535 125 61 1,000 5,127E-03 0,06231995 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 5,127E-03 0,06201143 ! viral reproductive process GO:0022415 132 62 1,000 5,292E-03 0,06369158 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 5,977E-03 0,07157182 ! activation of MAPK activity GO:0000187 124 67 1,000 6,154E-03 0,07333217 ! viral reproduction GO:0016032 142 68 1,000 6,333E-03 0,07510364 ! regulation of lipase activity GO:0060191 137 68 1,000 6,333E-03 0,07474082 ! cell projection assembly GO:0030031 138 68 1,000 6,333E-03 0,07438149 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 6,515E-03 0,0761502 ! lung development GO:0030324 165 69 1,000 6,515E-03 0,07578758 ! homeostasis of number of cells GO:0048872 131 69 1,000 6,515E-03 0,0754284 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 6,515E-03 0,07507261 ! negative regulation of kinase activity GO:0033673 145 70 1,000 6,699E-03 0,07683194 ! appendage morphogenesis GO:0035107 150 72 1,000 7,074E-03 0,08075723 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 1,000 7,074E-03 0,08038161 ! actin filament organization GO:0007015 167 72 1,000 7,074E-03 0,08000947 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 7,074E-03 0,07964077 ! appendage development GO:0048736 151 73 1,000 7,265E-03 0,0814176 GO:0060173|limb development, ! regulation of immune effector process GO:0002697 156 73 1,000 7,265E-03 0,08104583 ! negative regulation of transferase activity GO:0051348 155 74 1,000 7,459E-03 0,08282596 ! respiratory system development GO:0060541 175 74 1,000 7,459E-03 0,08245119 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 7,853E-03 0,08641458 ! lymphocyte differentiation GO:0030098 193 76 1,000 7,853E-03 0,08602707 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 8,053E-03 0,08782877 ! regulation of catabolic process GO:0009894 173 77 1,000 8,053E-03 0,08743842 ! blood coagulation GO:0007596 151 79 1,000 8,461E-03 0,09145861 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 1,000 8,461E-03 0,09105571 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 8,692E-03 0,09313079 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 8,692E-03 0,0927241 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 8,692E-03 0,09232095 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 8,692E-03 0,0919213 ! positive regulation of helicase activity GO:0051096 12 5 0,000 8,692E-03 0,09152508 ! neuron fate determination GO:0048664 7 5 0,000 8,692E-03 0,09113227 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,692E-03 0,09074282 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 8,692E-03 0,09035668 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 8,692E-03 0,08997381 ! polyol transport GO:0015791 12 5 0,000 8,692E-03 0,08959417 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 8,692E-03 0,08921773 ! response to superoxide GO:0000303 10 5 0,000 8,692E-03 0,08884443 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,692E-03 0,08847425 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 8,692E-03 0,08810713 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 8,692E-03 0,08774306 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 8,692E-03 0,08738197 ! female meiosis GO:0007143 10 5 0,000 8,692E-03 0,08702385 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 8,692E-03 0,08666865 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 8,692E-03 0,08631634 ! hypothalamus development GO:0021854 9 5 0,000 8,692E-03 0,08596688 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 8,692E-03 0,08562024 ! cobalt ion transport GO:0006824 11 5 0,000 8,692E-03 0,08527638 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 8,692E-03 0,08493528 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 8,692E-03 0,08459689 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 8,692E-03 0,08426119 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 8,692E-03 0,08392814 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 8,692E-03 0,08359771 ! embryonic camera-type eye development GO:0031076 12 5 0,000 8,692E-03 0,08326988 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 8,692E-03 0,08294461 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,692E-03 0,08262187 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 8,692E-03 0,08230163 ! transposition GO:0032196 9 5 0,000 8,692E-03 0,08198386 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 8,692E-03 0,08166854 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 8,692E-03 0,08135563 ! negative chemotaxis GO:0050919 16 5 0,000 8,692E-03 0,08104511 ! positive regulation of histone modification GO:0031058 6 5 0,000 8,692E-03 0,08073696 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 8,692E-03 0,08043113 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 8,692E-03 0,08012762 ! behavioral response to pain GO:0048266 10 5 0,000 8,692E-03 0,07982639 ! clathrin coat assembly GO:0048268 15 5 0,000 8,692E-03 0,07952741 ! Notch receptor processing GO:0007220 11 5 0,000 8,692E-03 0,07923067 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,692E-03 0,07893613 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 8,692E-03 0,07864378 ! micturition GO:0060073 9 5 0,000 8,692E-03 0,07835358 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 8,692E-03 0,07806551 ! copulation GO:0007620 9 5 0,000 8,692E-03 0,07777956 ! glial cell fate commitment GO:0021781 14 5 0,000 8,692E-03 0,07749569 ! protein maturation by protein folding GO:0022417 14 5 0,000 8,692E-03 0,07721389 ! bioluminescence GO:0008218 9 5 0,000 8,692E-03 0,07693413 ! spermidine metabolic process GO:0008216 7 5 0,000 8,692E-03 0,07665639 ! regulation of potassium ion transport GO:0043266 10 5 0,000 8,692E-03 0,07638065 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 8,692E-03 0,07610688 ! apoptotic cell clearance GO:0043277 23 5 0,000 8,692E-03 0,07583507 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 8,692E-03 0,07556519 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 8,692E-03 0,07529723 ! lipoprotein particle clearance GO:0034381 10 5 0,000 8,692E-03 0,07503116 ! grooming behavior GO:0007625 6 5 0,000 8,692E-03 0,07476697 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 8,692E-03 0,07450463 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 8,692E-03 0,07424412 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 8,692E-03 0,07398543 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,692E-03 0,07372854 ! response to protozoan GO:0001562 13 5 0,000 8,692E-03 0,07347342 ! lymph vessel development GO:0001945 10 5 0,000 8,692E-03 0,07322007 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 8,692E-03 0,07296845 ! endochondral ossification GO:0001958 17 5 0,000 8,692E-03 0,07271856 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 8,692E-03 0,07247037 ! single strand break repair GO:0000012 8 5 0,000 8,692E-03 0,07222388 ! parathyroid gland development GO:0060017 14 5 0,000 8,692E-03 0,07197905 ! anagen GO:0042640 7 5 0,000 8,692E-03 0,07173588 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 8,692E-03 0,07149434 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 8,692E-03 0,07125443 ! cytokine secretion GO:0050663 15 5 0,000 8,692E-03 0,07101612 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 8,692E-03 0,0707794 ! ceramide catabolic process GO:0046514 7 5 0,000 8,692E-03 0,07054425 ! skeletal myofibril assembly GO:0014866 12 5 0,000 8,692E-03 0,07031066 ! smooth muscle tissue development GO:0048745 32 5 0,000 8,692E-03 0,07007861 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 8,692E-03 0,06984809 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 8,692E-03 0,06961908 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 8,692E-03 0,06939157 ! cardiac muscle fiber development GO:0048739 12 5 0,000 8,692E-03 0,06916554 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 8,692E-03 0,06894097 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 8,692E-03 0,06871786 ! neutrophil mediated immunity GO:0002446 7 5 0,000 8,692E-03 0,06849619 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 8,692E-03 0,06827595 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 8,692E-03 0,06805711 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 8,692E-03 0,06783968 ! glycine biosynthetic process GO:0006545 7 5 0,000 8,692E-03 0,06762363 ! microvillus organization GO:0032528 8 5 0,000 8,692E-03 0,06740895 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 8,692E-03 0,06719563 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 8,692E-03 0,06698366 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 8,692E-03 0,06677302 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 8,692E-03 0,0665637 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 8,692E-03 0,06635569 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 8,692E-03 0,06614897 ! polyol catabolic process GO:0046174 9 5 0,000 8,692E-03 0,06594354 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 8,692E-03 0,06573938 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 8,692E-03 0,06553648 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 8,692E-03 0,06533483 ! muscle cell migration GO:0014812 8 5 0,000 8,692E-03 0,06513442 ! mitochondrial fission GO:0000266 8 5 0,000 8,692E-03 0,06493523 ! sister chromatid cohesion GO:0007062 15 5 0,000 8,692E-03 0,06473725 ! response to tumor necrosis factor GO:0034612 10 5 0,000 8,692E-03 0,06454048 ! mRNA transcription GO:0009299 10 5 0,000 8,692E-03 0,06434491 ! nerve growth factor processing GO:0032455 9 5 0,000 8,692E-03 0,06415051 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 8,692E-03 0,06395729 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 8,692E-03 0,06376522 ! anaerobic glycolysis GO:0019642 6 5 0,000 8,692E-03 0,06357431 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 8,692E-03 0,06338454 ! monocyte activation GO:0042117 10 5 0,000 8,692E-03 0,06319589 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 8,692E-03 0,06300837 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 8,692E-03 0,06282195 ! response to food GO:0032094 6 5 0,000 8,692E-03 0,06263664 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 8,692E-03 0,06245241 ! positive regulation of transporter activity GO:0032411 8 5 0,000 8,692E-03 0,06226927 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 8,692E-03 0,06208719 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,692E-03 0,06190618 ! forebrain neuron development GO:0021884 13 5 0,000 8,692E-03 0,06172622 ! lipoprotein catabolic process GO:0042159 11 5 0,000 8,692E-03 0,0615473 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 8,692E-03 0,06136942 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 8,692E-03 0,06119256 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 8,692E-03 0,06101672 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,692E-03 0,06084189 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 8,692E-03 0,06066806 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 8,692E-03 0,06049521 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 8,692E-03 0,06032335 ! lipid glycosylation GO:0030259 7 5 0,000 8,692E-03 0,06015246 ! nucleobase transport GO:0015851 6 5 0,000 8,692E-03 0,05998254 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,692E-03 0,05981358 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 8,692E-03 0,05964556 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 8,692E-03 0,05947849 ! basic amino acid transport GO:0015802 12 5 0,000 8,692E-03 0,05931234 ! cellular glucose homeostasis GO:0001678 6 5 0,000 8,692E-03 0,05914713 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 8,692E-03 0,05898283 ! actin nucleation GO:0045010 11 5 0,000 8,692E-03 0,05881944 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,692E-03 0,05865696 ! depurination GO:0045007 5 5 0,000 8,692E-03 0,05849537 ! depyrimidination GO:0045008 10 5 0,000 8,692E-03 0,05833467 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 8,692E-03 0,05817485 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,692E-03 0,0580159 ! G2/M transition checkpoint GO:0031576 8 5 0,000 8,692E-03 0,05785782 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 8,692E-03 0,0577006 ! zinc ion homeostasis GO:0055069 9 5 0,000 8,692E-03 0,05754423 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 8,692E-03 0,0573887 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 8,692E-03 0,05723401 ! forebrain morphogenesis GO:0048853 13 5 0,000 8,692E-03 0,05708016 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 8,692E-03 0,05692713 ! activated T cell proliferation GO:0050798 16 5 0,000 8,692E-03 0,05677492 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 8,692E-03 0,05662352 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 8,692E-03 0,05647292 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 8,692E-03 0,05632313 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,692E-03 0,05617413 ! gamma-delta T cell activation GO:0046629 6 5 0,000 8,692E-03 0,05602591 ! response to arsenic GO:0046685 11 5 0,000 8,692E-03 0,05587847 ! mast cell degranulation GO:0043303 7 5 0,000 8,692E-03 0,05573181 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 8,692E-03 0,05558591 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 8,692E-03 0,05544078 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 8,692E-03 0,0552964 ! response to mercury ion GO:0046689 8 5 0,000 8,692E-03 0,05515278 ! response to cadmium ion GO:0046686 7 5 0,000 8,692E-03 0,05500989 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 8,692E-03 0,05486775 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 8,692E-03 0,05472634 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 8,692E-03 0,05458565 ! bile acid biosynthetic process GO:0006699 7 5 0,000 8,692E-03 0,05444569 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 8,692E-03 0,05430644 ! ganglioside catabolic process GO:0006689 12 5 0,000 8,692E-03 0,05416791 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 8,692E-03 0,05403007 ! decidualization GO:0046697 11 5 0,000 8,692E-03 0,05389294 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 8,692E-03 0,0537565 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 8,692E-03 0,05362076 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 8,692E-03 0,05348569 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 8,692E-03 0,05335131 ! embryonic cleavage GO:0040016 6 5 0,000 8,692E-03 0,05321759 ! peroxisome fission GO:0016559 5 5 0,000 8,692E-03 0,05308455 ! histone demethylation GO:0016577 13 5 0,000 8,692E-03 0,05295217 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 8,692E-03 0,05282045 ! mitotic recombination GO:0006312 9 5 0,000 8,692E-03 0,05268938 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 8,692E-03 0,05255896 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 8,692E-03 0,05242918 ! metaphase plate congression GO:0051310 7 5 0,000 8,692E-03 0,05230005 ! regulation of sterol transport GO:0032371 7 5 0,000 8,692E-03 0,05217155 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 8,692E-03 0,05204368 ! enteric nervous system development GO:0048484 8 5 0,000 8,692E-03 0,05191643 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 8,692E-03 0,0517898 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 8,692E-03 0,05166379 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 8,692E-03 0,0515384 ! muscle cell proliferation GO:0033002 12 5 0,000 8,692E-03 0,05141361 ! skeletal muscle regeneration GO:0043403 8 5 0,000 8,692E-03 0,05128942 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 8,692E-03 0,05116583 ! B cell homeostasis GO:0001782 13 5 0,000 8,692E-03 0,05104284 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 8,692E-03 0,05092043 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 8,692E-03 0,05079861 ! metaphase GO:0051323 11 5 0,000 8,692E-03 0,05067737 ! melatonin biosynthetic process GO:0030187 7 5 0,000 8,692E-03 0,05055671 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 8,692E-03 0,05043663 ! cellular response to nutrient GO:0031670 8 5 0,000 8,692E-03 0,05031711 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 8,692E-03 0,05019815 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 8,692E-03 0,05007976 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 8,692E-03 0,04996193 ! regulation of hair follicle development GO:0051797 10 5 0,000 8,692E-03 0,04984465 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 8,692E-03 0,04972791 ! response to redox state GO:0051775 6 5 0,000 8,692E-03 0,04961173 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 8,692E-03 0,04949608 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 8,692E-03 0,04938098 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 8,692E-03 0,0492664 ! brown fat cell differentiation GO:0050873 7 5 0,000 8,692E-03 0,04915236 ! regulation of telomerase activity GO:0051972 7 5 0,000 8,692E-03 0,04903884 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,692E-03 0,04892585 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 8,692E-03 0,04881338 ! porphyrin catabolic process GO:0006787 12 5 0,000 8,692E-03 0,04870142 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 8,692E-03 0,04858998 ! striatum development GO:0021756 14 5 0,000 8,692E-03 0,04847904 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 8,692E-03 0,04836861 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 8,692E-03 0,04825868 ! glial cell migration GO:0008347 10 5 0,000 8,692E-03 0,04814925 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 8,692E-03 0,04804032 ! neural plate morphogenesis GO:0001839 7 5 0,000 8,692E-03 0,04793187 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 8,692E-03 0,04782392 ! somatic stem cell maintenance GO:0035019 15 5 0,000 8,692E-03 0,04771645 ! T cell activation during immune response GO:0002286 9 5 0,000 8,692E-03 0,04760946 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 8,692E-03 0,04750295 ! negative regulation of lipase activity GO:0060192 8 5 0,000 8,692E-03 0,04739692 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 8,692E-03 0,04729136 ! neuroprotection GO:0043526 8 5 0,000 8,692E-03 0,04718627 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 8,692E-03 0,04708164 ! regulation of sensory perception GO:0051931 8 5 0,000 8,692E-03 0,04697748 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 8,692E-03 0,04687377 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 8,692E-03 0,04677053 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 8,692E-03 0,04666774 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 8,692E-03 0,04656539 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 8,692E-03 0,0464635 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 8,692E-03 0,04636205 ! sequestering of calcium ion GO:0051208 7 5 0,000 8,692E-03 0,04626104 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 8,692E-03 0,04616048 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 8,692E-03 0,04606035 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 8,692E-03 0,04596065 ! spindle assembly GO:0051225 6 5 0,000 8,692E-03 0,04586138 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 8,692E-03 0,04576254 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 8,692E-03 0,04566413 ! protein palmitoylation GO:0018345 12 5 0,000 8,692E-03 0,04556614 ! drug metabolic process GO:0017144 7 5 0,000 8,692E-03 0,04546856 ! stem cell division GO:0017145 11 5 0,000 8,692E-03 0,04537141 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 8,692E-03 0,04527467 ! carnitine metabolic process GO:0009437 8 5 0,000 8,692E-03 0,04517834 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 8,692E-03 0,04508242 ! muscle cell differentiation GO:0042692 178 81 1,000 8,878E-03 0,04594894 ! response to hypoxia GO:0001666 178 81 1,000 8,878E-03 0,0458518 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 8,878E-03 0,04575506 ! regulation of peptidase activity GO:0052547 150 82 1,000 9,089E-03 0,04674804 ! response to oxygen levels GO:0070482 183 83 1,000 9,303E-03 0,0477484 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 9,303E-03 0,0476483 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 9,303E-03 0,04754862 ! hemostasis GO:0007599 165 85 1,000 9,738E-03 0,04966703 ! regulation of protein transport GO:0051223 165 87 1,000 0,01018196 0,05182195 GO:0070201|regulation of establishment of protein localization, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0104211 0,05292878 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0104211 0,05281897 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,0104211 0,05270961 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,0104211 0,05260071 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0104211 0,05249225 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,0104211 0,05238424 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,0104211 0,05227668 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,0104211 0,05216955 ! response to oxygen radical GO:0000305 11 6 0,000 0,0104211 0,05206287 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,0104211 0,05195662 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,0104211 0,0518508 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,0104211 0,05174541 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0104211 0,05164045 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0104211 0,05153591 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,0104211 0,0514318 ! forebrain regionalization GO:0021871 9 6 0,000 0,0104211 0,05132811 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0104211 0,05122483 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0104211 0,05112197 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,0104211 0,05101952 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0104211 0,05091748 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,0104211 0,05081585 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,0104211 0,05071462 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0104211 0,0506138 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,0104211 0,05051338 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,0104211 0,05041335 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0104211 0,05031372 ! malate metabolic process GO:0006108 13 6 0,000 0,0104211 0,05021448 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,0104211 0,05011563 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,0104211 0,05001717 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,0104211 0,0499191 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,0104211 0,04982141 ! protein refolding GO:0042026 15 6 0,000 0,0104211 0,0497241 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0104211 0,04962718 ! opsonization GO:0008228 8 6 0,000 0,0104211 0,04953063 ! mating behavior GO:0007617 7 6 0,000 0,0104211 0,04943445 ! erythrocyte maturation GO:0043249 8 6 0,000 0,0104211 0,04933865 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,0104211 0,04924321 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,0104211 0,04914815 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,0104211 0,04905345 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,0104211 0,04895912 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0104211 0,04886515 ! response to interferon-gamma GO:0034341 16 6 0,000 0,0104211 0,04877154 ! toxin metabolic process GO:0009404 11 6 0,000 0,0104211 0,04867828 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0104211 0,04858538 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,0104211 0,04849284 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,0104211 0,04840065 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,0104211 0,04830881 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,0104211 0,04821731 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,0104211 0,04812617 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,0104211 0,04803536 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0104211 0,0479449 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,0104211 0,04785478 ! thymic T cell selection GO:0045061 16 6 0,000 0,0104211 0,04776499 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,0104211 0,04767555 ! protein lipoylation GO:0009249 10 6 0,000 0,0104211 0,04758643 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,0104211 0,04749765 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,0104211 0,0474092 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0104211 0,04732108 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,0104211 0,04723329 ! glutamate catabolic process GO:0006538 12 6 0,000 0,0104211 0,04714582 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,0104211 0,04705867 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0104211 0,04697185 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,0104211 0,04688534 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0104211 0,04679916 ! hyperosmotic response GO:0006972 10 6 0,000 0,0104211 0,04671329 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,0104211 0,04662773 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,0104211 0,04654249 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,0104211 0,04645756 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0104211 0,04637294 ! urea metabolic process GO:0019627 7 6 0,000 0,0104211 0,04628862 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0104211 0,04620461 ! neutrophil activation GO:0042119 7 6 0,000 0,0104211 0,04612091 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0104211 0,04603751 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,0104211 0,04595441 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0104211 0,04587161 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,0104211 0,0457891 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,0104211 0,0457069 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0104211 0,04562498 ! neuron apoptosis GO:0051402 15 6 0,000 0,0104211 0,04554337 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0104211 0,04546204 ! T cell mediated immunity GO:0002456 17 6 0,000 0,0104211 0,045381 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0104211 0,04530025 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,0104211 0,04521979 ! carnitine transport GO:0015879 10 6 0,000 0,0104211 0,04513961 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0104211 0,04505972 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,0104211 0,04498011 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,0104211 0,04490078 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,0104211 0,04482173 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,0104211 0,04474296 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0104211 0,04466446 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,0104211 0,04458624 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,0104211 0,04450829 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,0104211 0,04443061 ! establishment of spindle localization GO:0051293 16 6 0,000 0,0104211 0,04435321 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,0104211 0,04427607 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0104211 0,0441992 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,0104211 0,0441226 ! response to UV-C GO:0010225 14 6 0,000 0,0104211 0,04404627 ! astrocyte development GO:0014002 16 6 0,000 0,0104211 0,04397019 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,0104211 0,04389438 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0104211 0,04381883 ! interaction with symbiont GO:0051702 14 6 0,000 0,0104211 0,04374354 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0104211 0,04366851 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,0104211 0,04359374 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,0104211 0,04351922 ! response to copper ion GO:0046688 10 6 0,000 0,0104211 0,04344495 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,0104211 0,04337094 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,0104211 0,04329718 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0104211 0,04322367 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,0104211 0,04315041 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0104211 0,0430774 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,0104211 0,04300463 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0104211 0,04293211 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,0104211 0,04285983 ! hair follicle maturation GO:0048820 8 6 0,000 0,0104211 0,0427878 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0104211 0,04271601 ! Schwann cell development GO:0014044 15 6 0,000 0,0104211 0,04264446 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,0104211 0,04257315 ! response to pheromone GO:0019236 6 6 0,000 0,0104211 0,04250207 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,0104211 0,04243124 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,0104211 0,04236063 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,0104211 0,04229027 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,0104211 0,04222014 ! subpallium development GO:0021544 15 6 0,000 0,0104211 0,04215023 ! neural tube patterning GO:0021532 8 6 0,000 0,0104211 0,04208056 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,0104211 0,04201112 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,0104211 0,04194191 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0104211 0,04187293 ! G2 phase GO:0051319 16 6 0,000 0,0104211 0,04180417 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,0104211 0,04173564 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,0104211 0,04166733 ! oxygen homeostasis GO:0032364 10 6 0,000 0,0104211 0,04159925 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0104211 0,04153139 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,0104211 0,04146375 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0104211 0,04139633 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,0104211 0,04132913 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0104211 0,04126214 ! receptor internalization GO:0031623 11 6 0,000 0,0104211 0,04119537 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,0104211 0,04112882 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,0104211 0,04106249 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,0104211 0,04099636 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0104211 0,04093045 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,0104211 0,04086475 ! protein deubiquitination GO:0016579 16 6 0,000 0,0104211 0,04079927 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,0104211 0,04073399 ! protein destabilization GO:0031648 9 6 0,000 0,0104211 0,04066892 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,0104211 0,04060405 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0104211 0,0405394 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,0104211 0,04047495 ! regulation of viral transcription GO:0046782 11 6 0,000 0,0104211 0,0404107 ! progesterone metabolic process GO:0042448 12 6 0,000 0,0104211 0,04034666 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,0104211 0,04028282 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,0104211 0,04021918 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,0104211 0,04015574 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0104211 0,04009251 ! determination of adult lifespan GO:0008340 17 6 0,000 0,0104211 0,04002947 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,0104211 0,03996663 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0104211 0,03990398 ! neural plate development GO:0001840 9 6 0,000 0,0104211 0,03984154 ! catecholamine transport GO:0051937 9 6 0,000 0,0104211 0,03977928 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,0104211 0,03971723 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0104211 0,03965536 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,0104211 0,03959369 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,0104211 0,03953221 ! maternal placenta development GO:0001893 12 6 0,000 0,0104211 0,03947092 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,0104211 0,03940982 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0104211 0,0393489 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,0104211 0,03928818 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,0104211 0,03922764 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,0104211 0,03916729 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,0104211 0,03910713 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,0104211 0,03904715 GO:0055081|anion homeostasis, ! ossification GO:0001503 205 91 1,000 0,01109589 0,04151189 ! bone development GO:0060348 206 92 1,000 0,01132984 0,04232232 ! regulation of membrane potential GO:0042391 179 94 1,000 0,01180424 0,04402711 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,01204468 0,0448554 ! tRNA transcription GO:0009304 17 7 0,000 0,01214753 0,04516958 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01214753 0,04510093 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01214753 0,04503249 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01214753 0,04496426 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01214753 0,04489624 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01214753 0,04482842 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01214753 0,0447608 ! sleep GO:0030431 16 7 0,000 0,01214753 0,04469339 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01214753 0,04462618 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01214753 0,04455918 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01214753 0,04449237 ! prostate gland development GO:0030850 14 7 0,000 0,01214753 0,04442577 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01214753 0,04435936 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01214753 0,04429315 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01214753 0,04422714 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01214753 0,04416133 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01214753 0,04409571 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01214753 0,04403028 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01214753 0,04396505 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01214753 0,04390002 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01214753 0,04383517 ! glycolipid transport GO:0046836 11 7 0,000 0,01214753 0,04377052 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01214753 0,04370606 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01214753 0,04364178 ! neuron adhesion GO:0007158 14 7 0,000 0,01214753 0,0435777 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01214753 0,0435138 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01214753 0,04345009 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01214753 0,04338657 ! mRNA stabilization GO:0048255 18 7 0,000 0,01214753 0,04332323 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01214753 0,04326008 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01214753 0,04319711 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01214753 0,04313432 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01214753 0,04307171 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01214753 0,04300929 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01214753 0,04294705 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01214753 0,04288499 ! lipoprotein transport GO:0042953 14 7 0,000 0,01214753 0,0428231 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01214753 0,0427614 ! rhythmic behavior GO:0007622 17 7 0,000 0,01214753 0,04269987 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01214753 0,04263852 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01214753 0,04257735 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01214753 0,04251635 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01214753 0,04245552 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01214753 0,04239487 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01214753 0,0423344 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01214753 0,04227409 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01214753 0,04221396 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01214753 0,04215399 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01214753 0,0420942 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01214753 0,04203458 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01214753 0,04197512 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01214753 0,04191584 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01214753 0,04185672 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01214753 0,04179776 ! spinal cord patterning GO:0021511 14 7 0,000 0,01214753 0,04173898 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01214753 0,04168035 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01214753 0,0416219 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01214753 0,0415636 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01214753 0,04150547 ! adrenal gland development GO:0030325 17 7 0,000 0,01214753 0,0414475 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01214753 0,0413897 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01214753 0,04133205 ! ovulation GO:0030728 10 7 0,000 0,01214753 0,04127456 ! adenohypophysis development GO:0021984 11 7 0,000 0,01214753 0,04121724 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01214753 0,04116007 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01214753 0,04110306 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01214753 0,04104621 ! microtubule nucleation GO:0007020 21 7 0,000 0,01214753 0,04098952 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01214753 0,04093298 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01214753 0,0408766 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01214753 0,04082037 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01214753 0,0407643 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01214753 0,04070838 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01214753 0,04065262 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01214753 0,04059701 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01214753 0,04054155 ! galactose metabolic process GO:0006012 13 7 0,000 0,01214753 0,04048624 ! response to dietary excess GO:0002021 8 7 0,000 0,01214753 0,04043108 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01214753 0,04037607 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01214753 0,04032121 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01214753 0,0402665 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01214753 0,04021194 ! organ growth GO:0035265 15 7 0,000 0,01214753 0,04015753 ! nucleoside transport GO:0015858 11 7 0,000 0,01214753 0,04010326 ! nucleoside salvage GO:0043174 11 7 0,000 0,01214753 0,04004914 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01214753 0,03999516 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01214753 0,03994133 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01214753 0,03988765 ! parturition GO:0007567 16 7 0,000 0,01214753 0,03983411 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01214753 0,03978071 ! rRNA modification GO:0000154 14 7 0,000 0,01214753 0,03972746 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01214753 0,03967435 ! spindle checkpoint GO:0031577 16 7 0,000 0,01214753 0,03962138 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01214753 0,03956855 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01214753 0,03951586 ! monocyte differentiation GO:0030224 16 7 0,000 0,01214753 0,03946331 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01214753 0,03941091 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01214753 0,03935864 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01214753 0,03930651 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01214753 0,03925451 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01214753 0,03920266 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01214753 0,03915094 ! fibrinolysis GO:0042730 11 7 0,000 0,01214753 0,03909936 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01214753 0,03904791 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01214753 0,0389966 ! eating behavior GO:0042755 8 7 0,000 0,01214753 0,03894542 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01214753 0,03889438 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01214753 0,03884347 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01214753 0,03879269 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01214753 0,03874205 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01214753 0,03869154 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01214753 0,03864116 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01214753 0,03859091 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01214753 0,03854079 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01214753 0,03849081 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01214753 0,03844095 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01214753 0,03839122 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01214753 0,03834162 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01214753 0,03829214 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01214753 0,0382428 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01214753 0,03819358 ! histone ubiquitination GO:0016574 9 7 0,000 0,01214753 0,03814449 ! regulation of meiosis GO:0040020 12 7 0,000 0,01214753 0,03809552 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01214753 0,03804668 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01214753 0,03799797 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01214753 0,03794938 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01214753 0,03790091 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01214753 0,03785257 ! transcription termination GO:0006353 14 7 0,000 0,01214753 0,03780435 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01214753 0,03775625 ! anaphase GO:0051322 18 7 0,000 0,01214753 0,03770827 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01214753 0,03766042 ! axonal fasciculation GO:0007413 19 7 0,000 0,01214753 0,03761269 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01214753 0,03756508 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01214753 0,03751759 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01214753 0,03747022 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01214753 0,03742297 ! diuresis GO:0030146 12 7 0,000 0,01214753 0,03737583 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01214753 0,03732882 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01214753 0,03728192 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01214753 0,03723515 ! antibiotic transport GO:0042891 9 7 0,000 0,01214753 0,03718849 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01214753 0,03714194 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01214753 0,03709551 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01214753 0,0370492 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01214753 0,03700301 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01214753 0,03695693 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01214753 0,03691096 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01214753 0,03686511 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01214753 0,03681937 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01214753 0,03677374 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01214753 0,03672823 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01214753 0,03668283 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01214753 0,03663755 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01214753 0,03659237 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01214753 0,0365473 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01214753 0,03650235 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01214753 0,03645751 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01214753 0,03641277 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01214753 0,03636815 ! muscle adaptation GO:0043500 13 7 0,000 0,01214753 0,03632364 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01214753 0,03627923 ! retina homeostasis GO:0001895 12 7 0,000 0,01214753 0,03623493 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01214753 0,03619075 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01214753 0,03614666 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01214753 0,03610269 ! regulation of protein localization GO:0032880 188 97 1,000 0,01253198 0,03720003 ! leukocyte differentiation GO:0002521 232 98 1,000 0,01277883 0,03788676 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,01277883 0,03784083 ! forebrain development GO:0030900 210 98 1,000 0,01277883 0,03779502 ! mRNA transport GO:0051028 185 100 1,000 0,0132789 0,03922653 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,013871 0,04092614 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,013871 0,04087677 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,013871 0,04082752 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,013871 0,04077839 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,013871 0,04072938 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,013871 0,04068048 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,013871 0,0406317 ! male meiosis GO:0007140 9 8 0,000 0,013871 0,04058304 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,013871 0,0405345 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,013871 0,04048607 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,013871 0,04043776 ! meiotic prophase I GO:0007128 14 8 0,000 0,013871 0,04038956 ! response to zinc ion GO:0010043 12 8 0,000 0,013871 0,04034148 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,013871 0,04029351 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,013871 0,04024566 ! oligopeptide transport GO:0006857 16 8 0,000 0,013871 0,04019791 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,013871 0,04015029 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,013871 0,04010277 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,013871 0,04005537 ! signal peptide processing GO:0006465 12 8 0,000 0,013871 0,04000808 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,013871 0,0399609 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,013871 0,03991383 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,013871 0,03986687 ! succinate metabolic process GO:0006105 17 8 0,000 0,013871 0,03982003 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,013871 0,03977329 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,013871 0,03972666 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,013871 0,03968014 ! estrogen metabolic process GO:0008210 17 8 0,000 0,013871 0,03963373 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,013871 0,03958743 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,013871 0,03954124 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,013871 0,03949515 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,013871 0,03944918 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,013871 0,0394033 ! reflex GO:0060004 17 8 0,000 0,013871 0,03935754 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,013871 0,03931188 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,013871 0,03926633 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,013871 0,03922088 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,013871 0,03917554 ! pigment granule organization GO:0048753 17 8 0,000 0,013871 0,0391303 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,013871 0,03908517 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,013871 0,03904014 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,013871 0,03899521 ! astrocyte differentiation GO:0048708 19 8 0,000 0,013871 0,03895039 ! histidine catabolic process GO:0006548 10 8 0,000 0,013871 0,03890567 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,013871 0,03886106 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,013871 0,03881654 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,013871 0,03877213 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,013871 0,03872782 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,013871 0,03868361 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,013871 0,0386395 ! melanin metabolic process GO:0006582 17 8 0,000 0,013871 0,03859549 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,013871 0,03855158 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,013871 0,03850777 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,013871 0,03846407 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,013871 0,03842046 ! macrophage activation GO:0042116 13 8 0,000 0,013871 0,03837694 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,013871 0,03833353 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,013871 0,03829022 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,013871 0,038247 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,013871 0,03820388 ! purine salvage GO:0043101 12 8 0,000 0,013871 0,03816086 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,013871 0,03811793 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,013871 0,0380751 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,013871 0,03803237 ! osteoblast development GO:0002076 17 8 0,000 0,013871 0,03798973 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,013871 0,03794719 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,013871 0,03790474 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,013871 0,03786239 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,013871 0,03782014 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,013871 0,03777797 ! response to UV-B GO:0010224 17 8 0,000 0,013871 0,0377359 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,013871 0,03769393 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,013871 0,03765205 ! intermediate filament organization GO:0045109 12 8 0,000 0,013871 0,03761026 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,013871 0,03756856 ! cellular extravasation GO:0045123 13 8 0,000 0,013871 0,03752696 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,013871 0,03748544 ! response to antibiotic GO:0046677 11 8 0,000 0,013871 0,03744402 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,013871 0,0374027 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,013871 0,03736146 ! DNA topological change GO:0006265 12 8 0,000 0,013871 0,03732031 ! response to tropane GO:0014073 15 8 0,000 0,013871 0,03727925 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,013871 0,03723829 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,013871 0,03719741 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,013871 0,03715662 ! mast cell activation GO:0045576 14 8 0,000 0,013871 0,03711593 ! multicellular organismal aging GO:0010259 20 8 0,000 0,013871 0,03707532 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,013871 0,0370348 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,013871 0,03699437 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,013871 0,03695403 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,013871 0,03691377 ! nucleosome disassembly GO:0006337 14 8 0,000 0,013871 0,0368736 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,013871 0,03683352 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,013871 0,03679353 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,013871 0,03675362 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,013871 0,0367138 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,013871 0,03667407 ! intracellular lipid transport GO:0032365 16 8 0,000 0,013871 0,03663442 ! response to tumor cell GO:0002347 16 8 0,000 0,013871 0,03659486 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,013871 0,03655538 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,013871 0,03651599 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,013871 0,03647669 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,013871 0,03643746 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,013871 0,03639833 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,013871 0,03635927 ! hormone catabolic process GO:0042447 17 8 0,000 0,013871 0,0363203 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,013871 0,03628142 GO:0046479|glycosphingolipid catabolic process, ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,013871 0,03624261 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,013871 0,03620389 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,013871 0,03616525 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,013871 0,0361267 ! adult feeding behavior GO:0008343 10 8 0,000 0,013871 0,03608822 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,013871 0,03604983 ! ATP catabolic process GO:0006200 11 8 0,000 0,013871 0,03601152 ! blastocyst growth GO:0001832 19 8 0,000 0,013871 0,03597329 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,013871 0,03593515 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,013871 0,03589708 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,013871 0,03585909 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,013871 0,03582119 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,013871 0,03578336 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,013871 0,03574561 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,013871 0,03570795 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,013871 0,03567036 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,013871 0,03563285 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,013871 0,03559542 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,013871 0,03555807 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,013871 0,0355208 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,013871 0,0354836 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,013871 0,03544649 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,013871 0,03540945 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,013871 0,03537249 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,013871 0,0353356 ! axon extension GO:0048675 16 9 0,000 0,0155915 0,03967713 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,0155915 0,03963584 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0155915 0,03959464 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,0155915 0,03955353 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,0155915 0,03951249 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,0155915 0,03947155 ! reproductive behavior GO:0019098 22 9 0,000 0,0155915 0,03943069 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0155915 0,03938991 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,0155915 0,03934922 ! UTP metabolic process GO:0046051 10 9 0,000 0,0155915 0,03930861 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,0155915 0,03926809 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,0155915 0,03922765 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,0155915 0,03918729 ! artery development GO:0060840 25 9 0,000 0,0155915 0,03914701 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,0155915 0,03910682 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,0155915 0,03906671 ! equilibrioception GO:0050957 20 9 0,000 0,0155915 0,03902669 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,0155915 0,03898674 ! chemosensory behavior GO:0007635 21 9 0,000 0,0155915 0,03894688 ! microtubule bundle formation GO:0001578 22 9 0,000 0,0155915 0,03890709 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0155915 0,03886739 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,0155915 0,03882777 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0155915 0,03878823 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,0155915 0,03874877 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,0155915 0,03870939 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,0155915 0,0386701 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,0155915 0,03863088 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0155915 0,03859174 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0155915 0,03855268 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,0155915 0,0385137 ! protein targeting to ER GO:0045047 25 9 0,000 0,0155915 0,03847479 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,0155915 0,03843597 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,0155915 0,03839722 ! T cell selection GO:0045058 27 9 0,000 0,0155915 0,03835855 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,0155915 0,03831996 ! glycine catabolic process GO:0006546 15 9 0,000 0,0155915 0,03828145 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,0155915 0,03824302 ! endosome organization GO:0007032 20 9 0,000 0,0155915 0,03820466 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0155915 0,03816638 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,0155915 0,03812817 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0155915 0,03809004 ! mannose metabolic process GO:0006013 13 9 0,000 0,0155915 0,03805199 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,0155915 0,03801402 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,0155915 0,03797612 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,0155915 0,03793829 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,0155915 0,03790054 ! receptor clustering GO:0043113 20 9 0,000 0,0155915 0,03786287 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,0155915 0,03782527 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0155915 0,03778774 ! retinol metabolic process GO:0042572 20 9 0,000 0,0155915 0,03775029 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,0155915 0,03771292 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,0155915 0,03767561 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,0155915 0,03763838 ! macrophage differentiation GO:0030225 15 9 0,000 0,0155915 0,03760123 ! oligodendrocyte development GO:0014003 11 9 0,000 0,0155915 0,03756415 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,0155915 0,03752714 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0155915 0,0374902 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,0155915 0,03745334 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0155915 0,03741655 ! response to amine stimulus GO:0014075 13 9 0,000 0,0155915 0,03737983 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0155915 0,03734318 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,0155915 0,03730661 ! erythrocyte development GO:0048821 17 9 0,000 0,0155915 0,0372701 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0155915 0,03723367 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,0155915 0,03719731 ! renal water homeostasis GO:0003091 15 9 0,000 0,0155915 0,03716102 ! postreplication repair GO:0006301 25 9 0,000 0,0155915 0,0371248 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,0155915 0,03708865 ! icosanoid secretion GO:0032309 15 9 0,000 0,0155915 0,03705257 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0155915 0,03701656 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,0155915 0,03698063 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,0155915 0,03694476 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,0155915 0,03690896 ! sterol catabolic process GO:0016127 14 9 0,000 0,0155915 0,03687323 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0155915 0,03683757 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,0155915 0,03680198 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,0155915 0,03676645 ! S phase GO:0051320 10 9 0,000 0,0155915 0,036731 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,0155915 0,03669561 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,0155915 0,03666029 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,0155915 0,03662504 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,0155915 0,03658986 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,0155915 0,03655475 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0155915 0,0365197 ! purine base metabolic process GO:0006144 25 9 0,000 0,0155915 0,03648472 ! pigment granule transport GO:0051904 17 9 0,000 0,0155915 0,0364498 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,0155915 0,03641496 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,0155915 0,03638018 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,0155915 0,03634546 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0155915 0,03631081 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,0155915 0,03627623 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,0155915 0,03624172 ! mitochondrion localization GO:0051646 18 9 0,000 0,0155915 0,03620727 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01730906 0,04015768 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01730906 0,04011958 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01730906 0,04008155 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01730906 0,04004359 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01730906 0,04000571 ! associative learning GO:0008306 21 10 0,000 0,01730906 0,03996789 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01730906 0,03993015 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01730906 0,03989248 ! phosphate transport GO:0006817 24 10 0,000 0,01730906 0,03985488 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01730906 0,03981736 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01730906 0,0397799 ! CTP metabolic process GO:0046036 11 10 0,000 0,01730906 0,03974251 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01730906 0,03970519 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01730906 0,03966795 ! GTP metabolic process GO:0046039 11 10 0,000 0,01730906 0,03963077 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01730906 0,03959366 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01730906 0,03955663 ! social behavior GO:0035176 29 10 0,000 0,01730906 0,03951966 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01730906 0,03948276 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01730906 0,03944593 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01730906 0,03940916 ! androgen metabolic process GO:0008209 17 10 0,000 0,01730906 0,03937247 ! phospholipid efflux GO:0033700 19 10 0,000 0,01730906 0,03933584 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01730906 0,03929929 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01730906 0,0392628 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01730906 0,03922637 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01730906 0,03919002 ! lung alveolus development GO:0048286 26 10 0,000 0,01730906 0,03915373 ! pathogenesis GO:0009405 17 10 0,000 0,01730906 0,03911751 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01730906 0,03908136 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01730906 0,03904527 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01730906 0,03900925 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01730906 0,0389733 ! endoderm development GO:0007492 18 10 0,000 0,01730906 0,03893741 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01730906 0,03890159 ! arginine catabolic process GO:0006527 17 10 0,000 0,01730906 0,03886584 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01730906 0,03883015 ! proline metabolic process GO:0006560 13 10 0,000 0,01730906 0,03879452 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01730906 0,03875897 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01730906 0,03872347 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01730906 0,03868804 ! V(D)J recombination GO:0033151 34 10 0,000 0,01730906 0,03865268 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01730906 0,03861738 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01730906 0,03858215 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01730906 0,03854698 ! B cell proliferation GO:0042100 19 10 0,000 0,01730906 0,03851187 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01730906 0,03847683 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01730906 0,03844185 ! multicellular organism growth GO:0035264 19 10 0,000 0,01730906 0,03840693 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01730906 0,03837208 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01730906 0,03833729 ! ruffle organization GO:0031529 17 10 0,000 0,01730906 0,03830257 ! epithelial cell development GO:0002064 21 10 0,000 0,01730906 0,0382679 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01730906 0,0382333 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01730906 0,03819876 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01730906 0,03816429 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01730906 0,03812988 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01730906 0,03809552 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01730906 0,03806124 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01730906 0,03802701 ! motor axon guidance GO:0008045 22 10 0,000 0,01730906 0,03799284 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01730906 0,03795874 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01730906 0,03792469 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01730906 0,03789071 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01730906 0,03785679 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01730906 0,03782293 ! segment specification GO:0007379 15 10 0,000 0,01730906 0,03778913 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01730906 0,03775539 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01730906 0,03772171 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01730906 0,03768809 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01730906 0,03765453 ! response to dsRNA GO:0043331 23 10 0,000 0,01730906 0,03762103 ! DNA ligation GO:0006266 18 10 0,000 0,01730906 0,03758758 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01730906 0,0375542 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01730906 0,03752088 ! melanosome localization GO:0032400 16 10 0,000 0,01730906 0,03748762 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01730906 0,03745441 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01730906 0,03742127 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01730906 0,03738818 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01730906 0,03735515 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01730906 0,03732218 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01730906 0,03728927 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01730906 0,03725642 ! protein sumoylation GO:0016925 17 10 0,000 0,01730906 0,03722362 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01730906 0,03719088 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01730906 0,0371582 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01730906 0,03712558 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01730906 0,03709301 ! salivary gland development GO:0007431 28 10 0,000 0,01730906 0,0370605 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01730906 0,03702805 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01730906 0,03699565 ! midbrain development GO:0030901 14 10 0,000 0,01730906 0,03696331 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01730906 0,03693103 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01730906 0,03689881 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01730906 0,03686664 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01730906 0,03683452 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01730906 0,03680246 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01730906 0,03677046 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01730906 0,03673852 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01730906 0,03670663 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01730906 0,03667479 ! detection of calcium ion GO:0005513 24 10 0,000 0,01730906 0,03664301 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01730906 0,03661128 ! blastocyst formation GO:0001825 18 10 0,000 0,01730906 0,03657961 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01730906 0,036548 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01730906 0,03651644 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01730906 0,03648493 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01730906 0,03645348 ! response to nicotine GO:0035094 20 10 0,000 0,01730906 0,03642208 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01730906 0,03639073 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01902367 0,03996115 ! respiratory burst GO:0045730 17 11 0,000 0,01902367 0,03992682 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01902367 0,03989255 ! neuron fate specification GO:0048665 18 11 0,000 0,01902367 0,03985833 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01902367 0,03982418 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01902367 0,03979008 ! thyroid gland development GO:0030878 26 11 0,000 0,01902367 0,03975605 ! synapsis GO:0007129 14 11 0,000 0,01902367 0,03972207 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01902367 0,03968814 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01902367 0,03965428 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01902367 0,03962047 ! response to pain GO:0048265 27 11 0,000 0,01902367 0,03958673 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01902367 0,03955304 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01902367 0,0395194 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01902367 0,03948583 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01902367 0,03945231 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01902367 0,03941884 ! bone resorption GO:0045453 16 11 0,000 0,01902367 0,03938544 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01902367 0,03935209 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01902367 0,0393188 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01902367 0,03928556 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01902367 0,03925238 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01902367 0,03921925 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01902367 0,03918619 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01902367 0,03915317 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01902367 0,03912022 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01902367 0,03908731 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01902367 0,03905447 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01902367 0,03902168 ! UV protection GO:0009650 20 11 0,000 0,01902367 0,03898894 ! adult heart development GO:0007512 16 11 0,000 0,01902367 0,03895626 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01902367 0,03892363 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01902367 0,03889106 ! macroautophagy GO:0016236 19 11 0,000 0,01902367 0,03885854 ! temperature homeostasis GO:0001659 18 11 0,000 0,01902367 0,03882608 ! behavioral fear response GO:0001662 27 11 0,000 0,01902367 0,03879367 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01902367 0,03876131 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01902367 0,03872901 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01902367 0,03869677 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01902367 0,03866457 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01902367 0,03863243 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01902367 0,03860035 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01902367 0,03856831 ! regulation of organ growth GO:0046620 14 11 0,000 0,01902367 0,03853633 ! pigment granule localization GO:0051875 20 11 0,000 0,01902367 0,0385044 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01902367 0,03847253 ! vasoconstriction GO:0042310 20 11 0,000 0,01902367 0,03844071 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01902367 0,03840894 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01902367 0,03837722 ! embryonic axis specification GO:0000578 19 11 0,000 0,01902367 0,03834556 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01902367 0,03831395 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01902367 0,03828239 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01902367 0,03825088 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01902367 0,03821942 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01902367 0,03818802 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01902367 0,03815666 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01902367 0,03812536 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01902367 0,03809411 ! prophase GO:0051324 17 11 0,000 0,01902367 0,03806291 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01902367 0,03803176 ! nucleosome positioning GO:0016584 15 11 0,000 0,01902367 0,03800067 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01902367 0,03796962 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01902367 0,03793863 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01902367 0,03790768 ! apical protein localization GO:0045176 18 11 0,000 0,01902367 0,03787679 ! acid secretion GO:0046717 20 11 0,000 0,01902367 0,03784594 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01902367 0,03781515 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01902367 0,0377844 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01902367 0,03775371 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01902367 0,03772307 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01902367 0,03769247 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01902367 0,03766193 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01902367 0,03763143 ! cholesterol efflux GO:0033344 21 11 0,000 0,01902367 0,03760098 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01902367 0,03757059 ! oocyte development GO:0048599 20 11 0,000 0,01902367 0,03754024 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01902367 0,03750994 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01902367 0,03747969 ! embryonic gut development GO:0048566 19 11 0,000 0,01902367 0,03744949 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01902367 0,03741934 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01902367 0,03738923 ! activation of innate immune response GO:0002218 16 11 0,000 0,01902367 0,03735918 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01902367 0,03732917 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01902367 0,03729921 ! lysogeny GO:0030069 22 11 0,000 0,01902367 0,0372693 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01902367 0,03723944 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01902367 0,03720962 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01902367 0,03717985 ! nucleus localization GO:0051647 22 11 0,000 0,01902367 0,03715013 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02073533 0,04046039 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02073533 0,0404281 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02073533 0,04039586 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,02073533 0,04036367 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02073533 0,04033154 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02073533 0,04029945 ! protein complex disassembly GO:0043241 28 12 0,000 0,02073533 0,04026742 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02073533 0,04023543 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02073533 0,0402035 ! hippocampus development GO:0021766 29 12 0,000 0,02073533 0,04017162 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02073533 0,04013979 ! T cell proliferation GO:0042098 32 12 0,000 0,02073533 0,040108 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02073533 0,04007627 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02073533 0,04004459 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02073533 0,04001296 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02073533 0,03998138 ! drug transport GO:0015893 16 12 0,000 0,02073533 0,03994985 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02073533 0,03991837 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02073533 0,03988694 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02073533 0,03985555 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02073533 0,03982422 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02073533 0,03979294 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02073533 0,0397617 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02073533 0,03973052 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02073533 0,03969938 ! lipid digestion GO:0044241 21 12 0,000 0,02073533 0,03966829 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02073533 0,03963725 ! entry into host cell GO:0030260 34 12 0,000 0,02073533 0,03960626 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02073533 0,03957532 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02073533 0,03954443 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02073533 0,03951358 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02073533 0,03948278 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02073533 0,03945203 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02073533 0,03942133 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02073533 0,03939068 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02073533 0,03936007 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02073533 0,03932951 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02073533 0,039299 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02073533 0,03926853 ! cranial nerve development GO:0021545 23 12 0,000 0,02073533 0,03923812 ! fucose catabolic process GO:0019317 25 12 0,000 0,02073533 0,03920775 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02073533 0,03917742 ! histone acetylation GO:0016573 27 12 0,000 0,02073533 0,03914715 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02073533 0,03911692 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02073533 0,03908674 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02073533 0,0390566 ! zymogen activation GO:0031638 18 12 0,000 0,02073533 0,03902651 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02073533 0,03899647 ! T cell homeostasis GO:0043029 28 12 0,000 0,02073533 0,03896647 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02073533 0,03893652 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02073533 0,03890661 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02073533 0,03887675 ! oocyte differentiation GO:0009994 21 12 0,000 0,02073533 0,03884694 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02073533 0,03881717 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02073533 0,03878745 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02073533 0,03875777 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02073533 0,03872814 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02073533 0,03869856 ! defense response to fungus GO:0050832 15 12 0,000 0,02073533 0,03866902 ! embryonic placenta development GO:0001892 21 12 0,000 0,02073533 0,03863952 ! response to cold GO:0009409 17 12 0,000 0,02073533 0,03861007 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02073533 0,03858066 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02073533 0,0385513 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02244405 0,04169644 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02244405 0,04166476 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02244405 0,04163312 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02244405 0,04160154 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02244405 0,04157 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02244405 0,0415385 ! peroxisomal transport GO:0043574 28 13 0,000 0,02244405 0,04150706 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02244405 0,04147566 ! cartilage condensation GO:0001502 22 13 0,000 0,02244405 0,04144431 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02244405 0,04141301 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02244405 0,04138175 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02244405 0,04135055 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02244405 0,04131939 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02244405 0,04128827 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02244405 0,0412572 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02244405 0,04122618 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02244405 0,04119521 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02244405 0,04116428 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02244405 0,0411334 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02244405 0,04110257 ! methionine metabolic process GO:0006555 31 13 0,000 0,02244405 0,04107178 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02244405 0,04104104 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02244405 0,04101034 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02244405 0,04097969 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02244405 0,04094908 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02244405 0,04091853 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02244405 0,04088801 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02244405 0,04085754 ! exocrine system development GO:0035272 34 13 0,000 0,02244405 0,04082712 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02244405 0,04079674 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02244405 0,04076641 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02244405 0,04073613 ! L-glutamate transport GO:0015813 30 13 0,000 0,02244405 0,04070588 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02244405 0,04067569 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02244405 0,04064553 ! protein homotetramerization GO:0051289 24 13 0,000 0,02244405 0,04061543 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02244405 0,04058536 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02244405 0,04055534 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02244405 0,04052537 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02244405 0,04049544 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02244405 0,04046555 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02244405 0,04043571 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02244405 0,04040591 ! histone methylation GO:0016571 29 13 0,000 0,02244405 0,04037616 ! chromatin silencing GO:0006342 29 13 0,000 0,02244405 0,04034645 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02244405 0,04031678 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02244405 0,04028716 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02244405 0,04025758 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02244405 0,04022804 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02244405 0,04019855 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02244405 0,0401691 ! spleen development GO:0048536 24 13 0,000 0,02244405 0,0401397 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02244405 0,04011033 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02244405 0,04008101 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02244405 0,04005173 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02244405 0,0400225 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02244405 0,03999331 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02244405 0,03996416 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02244405 0,03993505 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02244405 0,03990599 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02244405 0,03987696 ! insulin secretion GO:0030073 24 13 0,000 0,02244405 0,03984798 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02244405 0,03981904 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02244405 0,03979015 ! acrosome reaction GO:0007340 19 13 0,000 0,02244405 0,03976129 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02244405 0,03973248 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02244405 0,03970371 ! rRNA transcription GO:0009303 28 14 0,000 0,02414985 0,04269036 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02414985 0,04265949 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02414985 0,04262867 ! water transport GO:0006833 21 14 0,000 0,02414985 0,04259789 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02414985 0,04256715 ! non-recombinational repair GO:0000726 29 14 0,000 0,02414985 0,04253646 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02414985 0,04250582 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02414985 0,04247521 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02414985 0,04244466 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02414985 0,04241414 ! palate development GO:0060021 32 14 0,000 0,02414985 0,04238367 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02414985 0,04235325 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02414985 0,04232286 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02414985 0,04229253 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02414985 0,04226223 ! arginine metabolic process GO:0006525 21 14 0,000 0,02414985 0,04223198 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02414985 0,04220177 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02414985 0,0421716 ! regulation of heart rate GO:0002027 25 14 0,000 0,02414985 0,04214148 ! fear response GO:0042596 34 14 0,000 0,02414985 0,0421114 ! organic alcohol transport GO:0015850 29 14 0,000 0,02414985 0,04208136 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02414985 0,04205137 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02414985 0,04202142 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02414985 0,04199151 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02414985 0,04196164 ! bone mineralization GO:0030282 18 14 0,000 0,02414985 0,04193182 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02414985 0,04190204 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02414985 0,0418723 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02414985 0,0418426 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02414985 0,04181295 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02414985 0,04178334 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02414985 0,04175377 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02414985 0,04172424 ! ribosome assembly GO:0042255 18 14 0,000 0,02414985 0,04169475 ! cerebellum development GO:0021549 23 14 0,000 0,02414985 0,04166531 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02414985 0,0416359 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02414985 0,04160654 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02414985 0,04157722 ! response to gamma radiation GO:0010332 30 14 0,000 0,02414985 0,04154794 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02414985 0,0415187 ! NADP metabolic process GO:0006739 24 14 0,000 0,02414985 0,0414895 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02414985 0,04146035 ! oxygen transport GO:0015671 22 14 0,000 0,02414985 0,04143123 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02414985 0,04140216 ! male genitalia development GO:0030539 26 14 0,000 0,02414985 0,04137312 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02414985 0,04134413 ! regulation of axon extension GO:0030516 43 14 0,000 0,02414985 0,04131518 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02414985 0,04128627 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02414985 0,04125739 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02585271 0,04413569 ! lactation GO:0007595 30 15 0,000 0,02585271 0,04410486 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,02585271 0,04407409 ! reproductive cellular process GO:0048610 22 15 0,000 0,02585271 0,04404335 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02585271 0,04401266 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02585271 0,04398201 ! superoxide anion generation GO:0042554 22 15 0,000 0,02585271 0,0439514 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02585271 0,04392084 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02585271 0,04389032 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02585271 0,04385984 ! copper ion transport GO:0006825 22 15 0,000 0,02585271 0,0438294 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02585271 0,04379901 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02585271 0,04376865 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02585271 0,04373834 ! sulfate transport GO:0008272 27 15 0,000 0,02585271 0,04370807 ! response to cAMP GO:0051591 25 15 0,000 0,02585271 0,04367785 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02585271 0,04364766 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02585271 0,04361752 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02585271 0,04358742 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02585271 0,04355736 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02585271 0,04352734 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02585271 0,04349736 ! vesicle coating GO:0006901 38 15 0,000 0,02585271 0,04346742 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02585271 0,04343753 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02585271 0,04340767 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02585271 0,04337786 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02585271 0,04334809 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02585271 0,04331836 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02585271 0,04328867 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02585271 0,04325902 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02585271 0,04322941 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02585271 0,04319984 ! histone deacetylation GO:0016575 24 15 0,000 0,02585271 0,04317031 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02585271 0,04314082 ! water homeostasis GO:0030104 28 15 0,000 0,02585271 0,04311138 ! cofactor transport GO:0051181 30 15 0,000 0,02585271 0,04308197 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02585271 0,0430526 ! muscle maintenance GO:0046716 26 15 0,000 0,02585271 0,04302327 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02585271 0,04299399 ! intestinal absorption GO:0050892 31 15 0,000 0,02585271 0,04296474 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02585271 0,04293553 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02585271 0,04290636 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02585271 0,04287723 ! cell killing GO:0001906 32 15 0,000 0,02585271 0,04284815 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02585271 0,0428191 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,02585271 0,04279009 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02585271 0,04276111 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02585271 0,04273218 ! actin filament polymerization GO:0030041 27 15 0,000 0,02585271 0,04270329 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02585271 0,04267444 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02755265 0,04544978 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02755265 0,04541911 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02755265 0,04538848 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02755265 0,0453579 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02755265 0,04532735 ! bone remodeling GO:0046849 28 16 0,000 0,02755265 0,04529685 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02755265 0,04526639 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,02755265 0,04523597 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02755265 0,04520559 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02755265 0,04517525 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02755265 0,04514495 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02755265 0,04511469 ! startle response GO:0001964 28 16 0,000 0,02755265 0,04508447 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02755265 0,0450543 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02755265 0,04502416 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02755265 0,04499406 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02755265 0,04496401 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02755265 0,04493399 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02755265 0,04490401 ! response to osmotic stress GO:0006970 27 16 0,000 0,02755265 0,04487408 ! lysosomal transport GO:0007041 31 16 0,000 0,02755265 0,04484418 ! fructose metabolic process GO:0006000 25 16 0,000 0,02755265 0,04481433 ! L-amino acid transport GO:0015807 33 16 0,000 0,02755265 0,04478451 ! stem cell development GO:0048864 46 16 0,000 0,02755265 0,04475473 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02755265 0,04472499 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02755265 0,0446953 ! intermediate filament-based process GO:0045103 36 16 0,000 0,02755265 0,04466564 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02755265 0,04463602 ! axon cargo transport GO:0008088 46 16 0,000 0,02755265 0,04460644 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02755265 0,0445769 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02755265 0,0445474 ! DNA replication initiation GO:0006270 28 16 0,000 0,02755265 0,04451793 ! neuron recognition GO:0008038 40 16 0,000 0,02755265 0,04448851 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02755265 0,04445913 ! tissue regeneration GO:0042246 27 16 0,000 0,02755265 0,04442978 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02755265 0,04440047 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02755265 0,0443712 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02755265 0,04434197 ! biomineral formation GO:0031214 22 16 0,000 0,02755265 0,04431278 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02755265 0,04428363 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02755265 0,04425451 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02755265 0,04422544 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02755265 0,0441964 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02755265 0,0441674 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02755265 0,04413844 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02755265 0,04410951 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02755265 0,04408063 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02755265 0,04405178 ! peptide hormone processing GO:0016486 27 16 0,000 0,02755265 0,04402297 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02924967 0,04670388 ! metencephalon development GO:0022037 32 17 0,000 0,02924967 0,04667338 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02924967 0,04664291 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,02924967 0,04661248 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02924967 0,0465821 ! filopodium assembly GO:0046847 42 17 0,000 0,02924967 0,04655175 ! endothelial cell migration GO:0043542 31 17 0,000 0,02924967 0,04652144 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02924967 0,04649118 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02924967 0,04646095 ! glial cell development GO:0021782 28 17 0,000 0,02924967 0,04643076 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02924967 0,04640061 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02924967 0,0463705 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02924967 0,04634043 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02924967 0,04631039 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02924967 0,0462804 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02924967 0,04625045 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02924967 0,04622053 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02924967 0,04619065 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02924967 0,04616081 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02924967 0,04613101 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02924967 0,04610125 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02924967 0,04607153 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02924967 0,04604184 ! membrane budding GO:0006900 42 17 0,000 0,02924967 0,04601219 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02924967 0,04598259 ! regulation of protein binding GO:0043393 33 17 0,000 0,02924967 0,04595301 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02924967 0,04592348 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02924967 0,04589399 ! genitalia development GO:0048806 32 17 0,000 0,02924967 0,04586453 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02924967 0,04583511 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02924967 0,04580573 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02924967 0,04577639 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02924967 0,04574708 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02924967 0,04571781 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02924967 0,04568858 ! steroid catabolic process GO:0006706 34 17 0,000 0,02924967 0,04565939 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02924967 0,04563023 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02924967 0,04560111 ! gas transport GO:0015669 26 17 0,000 0,02924967 0,04557203 ! organic cation transport GO:0015695 32 17 0,000 0,02924967 0,04554298 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02924967 0,04551397 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02924967 0,045485 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02924967 0,04545607 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03094377 0,04805826 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03094377 0,04802773 ! limbic system development GO:0021761 40 18 0,000 0,03094377 0,04799723 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03094377 0,04796678 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03094377 0,04793636 ! adult walking behavior GO:0007628 36 18 0,000 0,03094377 0,04790598 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03094377 0,04787564 ! heart looping GO:0001947 34 18 0,000 0,03094377 0,04784534 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03094377 0,04781508 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03094377 0,04778485 ! centrosome cycle GO:0007098 26 18 0,000 0,03094377 0,04775467 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03094377 0,04772452 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03094377 0,04769441 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03094377 0,04766434 ! glycine metabolic process GO:0006544 30 18 0,000 0,03094377 0,0476343 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03094377 0,04760431 ! response to retinoic acid GO:0032526 31 18 0,000 0,03094377 0,04757435 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03094377 0,04754443 ! DNA integration GO:0015074 32 18 0,000 0,03094377 0,04751454 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03094377 0,0474847 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03094377 0,04745489 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03094377 0,04742512 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,03094377 0,04739539 ! neural crest cell migration GO:0001755 41 18 0,000 0,03094377 0,04736569 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03094377 0,04733603 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03094377 0,04730641 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03094377 0,04727682 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03094377 0,04724727 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,03094377 0,04721776 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,03094377 0,04718829 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03094377 0,04715885 ! detection of bacterium GO:0016045 22 18 0,000 0,03094377 0,04712945 ! nerve development GO:0021675 34 18 0,000 0,03094377 0,04710009 ! defense response to virus GO:0051607 43 18 0,000 0,03094377 0,04707076 ! microspike assembly GO:0030035 46 18 0,000 0,03094377 0,04704147 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03094377 0,04701221 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,03094377 0,046983 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03263497 0,04952002 ! positive regulation of translation GO:0045727 31 19 0,000 0,03263497 0,04948928 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03263497 0,04945858 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,03263497 0,04942792 ! neuron maturation GO:0042551 46 19 0,000 0,03263497 0,0493973 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03263497 0,04936671 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,03263497 0,04933616 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03263497 0,04930565 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03263497 0,04927518 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03263497 0,04924474 ! inositol metabolic process GO:0006020 33 19 0,000 0,03263497 0,04921434 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03263497 0,04918398 ! memory GO:0007613 34 19 0,000 0,03263497 0,04915366 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03263497 0,04912337 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03263497 0,04909313 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03263497 0,04906291 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03263497 0,04903274 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,03263497 0,0490026 ! cerebral cortex development GO:0021987 40 19 0,000 0,03263497 0,0489725 ! pigmentation during development GO:0048066 42 19 0,000 0,03263497 0,04894244 ! response to vitamin A GO:0033189 32 19 0,000 0,03263497 0,04891241 ! heme metabolic process GO:0042168 40 19 0,000 0,03263497 0,04888243 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03263497 0,04885247 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03263497 0,04882256 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03263497 0,04879268 ! response to fungus GO:0009620 26 19 0,000 0,03263497 0,04876284 ! peptide cross-linking GO:0018149 39 19 0,000 0,03263497 0,04873303 ! protein export from nucleus GO:0006611 40 19 0,000 0,03263497 0,04870326 ! heart process GO:0003015 32 19 0,000 0,03263497 0,04867353 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,03263497 0,04864383 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03263497 0,04861417 ! visual learning GO:0008542 38 19 0,000 0,03263497 0,04858454 ! cellular pigmentation GO:0033059 37 19 0,000 0,03263497 0,04855495 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03263497 0,0485254 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03263497 0,04849589 ! vitamin transport GO:0051180 31 19 0,000 0,03263497 0,0484664 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03263497 0,04843696 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03263497 0,04840755 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,03263497 0,04837818 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03263497 0,04834884 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03263497 0,04831954 ! cilium assembly GO:0042384 38 19 0,000 0,03263497 0,04829027 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03263497 0,04826104 ! protein secretion GO:0009306 45 20 0,000 0,03432327 0,050727 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,03432327 0,05069633 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,03432327 0,0506657 ! positive regulation of ossification GO:0045778 50 20 0,000 0,03432327 0,05063511 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,03432327 0,05060455 ! skin development GO:0043588 42 20 0,000 0,03432327 0,05057403 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,03432327 0,05054354 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,03432327 0,05051309 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,03432327 0,05048268 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,03432327 0,05045231 ! response to vitamin GO:0033273 36 20 0,000 0,03432327 0,05042197 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,03432327 0,05039167 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,03432327 0,0503614 ! bile acid metabolic process GO:0008206 34 20 0,000 0,03432327 0,05033117 ! response to alkaloid GO:0043279 38 20 0,000 0,03432327 0,05030098 ! retinoid metabolic process GO:0001523 34 20 0,000 0,03432327 0,05027083 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,03432327 0,05024071 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,03432327 0,05021062 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,03432327 0,05018057 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,03432327 0,05015056 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,03432327 0,05012058 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,03432327 0,05009064 ! actin filament bundle formation GO:0051017 47 20 0,000 0,03432327 0,05006074 ! body fluid secretion GO:0007589 33 20 0,000 0,03432327 0,05003087 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,03432327 0,05000104 ! peptide secretion GO:0002790 38 20 0,000 0,03432327 0,04997124 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,03432327 0,04994148 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,03432327 0,04991175 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,03432327 0,04988206 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,03432327 0,0498524 ! cell-cell junction organization GO:0045216 43 20 0,000 0,03432327 0,04982278 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,03432327 0,04979319 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,03432327 0,04976364 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,03432327 0,04973413 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,03432327 0,04970465 ! regulation of glucose import GO:0046324 30 20 0,000 0,03432327 0,0496752 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,03432327 0,04964579 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,03432327 0,04961641 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,03432327 0,04958707 ! negative regulation of translation GO:0017148 32 20 0,000 0,03432327 0,04955776 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,03432327 0,04952849 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,03600866 0,05192984 ! hormone secretion GO:0046879 39 21 0,000 0,03600866 0,05189921 ! cAMP metabolic process GO:0046058 41 21 0,000 0,03600866 0,05186861 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,03600866 0,05183804 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,03600866 0,05180751 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,03600866 0,05177702 ! ovarian follicle development GO:0001541 39 21 0,000 0,03600866 0,05174656 ! smooth muscle contraction GO:0006939 48 21 0,000 0,03600866 0,05171614 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,03600866 0,05168576 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,03600866 0,05165541 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,03600866 0,05162509 ! plasma membrane fusion GO:0045026 33 21 0,000 0,03600866 0,05159481 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,03600866 0,05156457 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,03600866 0,05153436 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,03600866 0,05150419 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,03600866 0,05147405 ! collagen fibril organization GO:0030199 62 21 0,000 0,03600866 0,05144395 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,03600866 0,05141388 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,03600866 0,05138385 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,03600866 0,05135386 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,03600866 0,05132389 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,03600866 0,05129397 ! collagen catabolic process GO:0030574 29 21 0,000 0,03600866 0,05126408 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,03600866 0,05123422 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,03600866 0,0512044 ! sperm-egg recognition GO:0035036 23 21 0,000 0,03600866 0,05117461 ! actin filament-based movement GO:0030048 47 21 0,000 0,03600866 0,05114486 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,03600866 0,05111514 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,03769116 0,05347242 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,03769116 0,05344138 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,03769116 0,05341039 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,03769116 0,05337942 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,03769116 0,0533485 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,03769116 0,05331761 ! microtubule-based transport GO:0010970 59 22 0,000 0,03769116 0,05328675 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,03769116 0,05325593 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,03769116 0,05322515 ! cellular response to starvation GO:0009267 37 22 0,000 0,03769116 0,0531944 ! vacuolar transport GO:0007034 41 22 0,000 0,03769116 0,05316369 ! central nervous system neuron development GO:0021954 47 22 0,000 0,03769116 0,05313301 ! fucose metabolic process GO:0006004 44 22 0,000 0,03769116 0,05310237 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,03769116 0,05307176 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,03769116 0,05304119 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,03769116 0,05301065 ! ureteric bud development GO:0001657 50 22 0,000 0,03769116 0,05298015 ! cell aging GO:0007569 48 22 0,000 0,03769116 0,05294969 ! stem cell differentiation GO:0048863 57 22 0,000 0,03769116 0,05291926 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,03769116 0,05288886 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,03769116 0,0528585 ! cytolysis GO:0019835 27 22 0,000 0,03769116 0,05282817 ! renal system process GO:0003014 42 22 0,000 0,03769116 0,05279788 ! vasodilation GO:0042311 40 22 0,000 0,03769116 0,05276762 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,03769116 0,0527374 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,03769116 0,05270721 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,03769116 0,05267706 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,03769116 0,05264694 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,03769116 0,05261686 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,03769116 0,05258681 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,03769116 0,05255679 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,03769116 0,05252681 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,03769116 0,05249687 ! sarcomere organization GO:0045214 32 22 0,000 0,03769116 0,05246695 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,03769116 0,05243708 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,03769116 0,05240723 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,03769116 0,05237742 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,03769116 0,05234764 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,03769116 0,0523179 ! gut development GO:0048565 44 22 0,000 0,03769116 0,05228819 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,03769116 0,05225852 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,03769116 0,05222887 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,03769116 0,05219927 ! protein stabilization GO:0050821 41 22 0,000 0,03769116 0,05216969 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,03937077 0,05446364 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,03937077 0,05443282 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,03937077 0,05440203 ! gluconeogenesis GO:0006094 38 23 0,000 0,03937077 0,05437128 ! glycerol metabolic process GO:0006071 40 23 0,000 0,03937077 0,05434056 ! viral genome replication GO:0019079 44 23 0,000 0,03937077 0,05430988 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,03937077 0,05427923 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,03937077 0,05424862 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,03937077 0,05421804 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,03937077 0,05418749 ! regeneration GO:0031099 42 23 0,000 0,03937077 0,05415698 ! axis specification GO:0009798 43 23 0,000 0,03937077 0,0541265 ! visual behavior GO:0007632 46 23 0,000 0,03937077 0,05409606 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,03937077 0,05406565 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 0,000 0,03937077 0,05403528 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,03937077 0,05400494 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,03937077 0,05397463 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,03937077 0,05394436 ! peroxisome organization GO:0007031 43 23 0,000 0,03937077 0,05391412 ! lysosome organization GO:0007040 47 23 0,000 0,03937077 0,05388392 ! vesicle targeting GO:0006903 49 23 0,000 0,03937077 0,05385375 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,03937077 0,05382361 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,03937077 0,05379351 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,03937077 0,05376344 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,03937077 0,0537334 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,03937077 0,0537034 ! DNA modification GO:0006304 36 23 0,000 0,03937077 0,05367343 ! fatty acid transport GO:0015908 47 23 0,000 0,03937077 0,0536435 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,03937077 0,0536136 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,03937077 0,05358373 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,03937077 0,05355389 ! hormone transport GO:0009914 41 23 0,000 0,03937077 0,05352409 ! cell-cell recognition GO:0009988 28 23 0,000 0,03937077 0,05349432 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,03937077 0,05346459 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,03937077 0,05343489 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,03937077 0,05340522 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0410475 0,05564874 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0410475 0,05561788 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,0410475 0,05558705 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,0410475 0,05555625 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0410475 0,05552549 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0410475 0,05549476 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0410475 0,05546407 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0410475 0,05543341 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,0410475 0,05540278 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,0410475 0,05537219 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0410475 0,05534163 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0410475 0,05531111 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0410475 0,05528062 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,0410475 0,05525016 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0410475 0,05521973 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0410475 0,05518934 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0410475 0,05515899 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,0410475 0,05512866 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0410475 0,05509837 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0410475 0,05506812 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0410475 0,05503789 ! pallium development GO:0021543 56 24 0,000 0,0410475 0,0550077 ! oogenesis GO:0048477 44 24 0,000 0,0410475 0,05497754 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0410475 0,05494742 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0410475 0,05491733 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0410475 0,05488727 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0410475 0,05485724 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0410475 0,05482725 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0410475 0,05479729 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0410475 0,05476736 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0410475 0,05473747 ! regulation of amine transport GO:0051952 41 24 0,000 0,0410475 0,0547076 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,04272135 0,05690744 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,04272135 0,05687643 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,04272135 0,05684545 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,04272135 0,05681451 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,04272135 0,05678359 ! leukocyte adhesion GO:0007159 55 25 0,000 0,04272135 0,05675272 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,04272135 0,05672187 ! phototransduction GO:0007602 37 25 0,000 0,04272135 0,05669106 ! keratinization GO:0031424 37 25 0,000 0,04272135 0,05666029 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,04272135 0,05662954 ! vacuole organization GO:0007033 49 25 0,000 0,04272135 0,05659883 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,04272135 0,05656816 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,04272135 0,05653751 ! receptor metabolic process GO:0043112 53 25 0,000 0,04272135 0,0565069 ! chromosome condensation GO:0030261 48 25 0,000 0,04272135 0,05647632 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,04272135 0,05644578 ! regulation of behavior GO:0050795 48 25 0,000 0,04272135 0,05641527 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,04272135 0,05638479 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,04272135 0,05635435 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,04272135 0,05632393 ! immunoglobulin production GO:0002377 62 25 0,000 0,04272135 0,05629355 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,04272135 0,05626321 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,04272135 0,05623289 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,04272135 0,05620261 ! liver development GO:0001889 55 25 0,000 0,04272135 0,05617236 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,04439232 0,05833805 ! myelination GO:0042552 50 26 0,000 0,04439232 0,05830668 ! initiation of viral infection GO:0019059 60 26 0,000 0,04439232 0,05827535 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,04439232 0,05824406 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,04439232 0,05821279 ! molting cycle process GO:0022404 52 26 0,000 0,04439232 0,05818156 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,04439232 0,05815037 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,04439232 0,0581192 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,04439232 0,05808807 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,04439232 0,05805698 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,04439232 0,05802591 ! digestive system process GO:0022600 49 26 0,000 0,04439232 0,05799488 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,04439232 0,05796389 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,04439232 0,05793292 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 63 26 0,000 0,04439232 0,05790199 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,04439232 0,0578711 ! neural crest cell development GO:0014032 59 26 0,000 0,04439232 0,05784023 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,04439232 0,0578094 ! negative regulation of cell development GO:0010721 83 26 0,000 0,04439232 0,0577786 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,04439232 0,05774783 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,04439232 0,0577171 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,04439232 0,0576864 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,04439232 0,05765573 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,04439232 0,0576251 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,04439232 0,05759449 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,04439232 0,05756392 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,04439232 0,05753339 ! blastocyst development GO:0001824 50 26 0,000 0,04439232 0,05750288 ! telomere organization GO:0032200 46 26 0,000 0,04439232 0,05747241 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,04439232 0,05744197 ! neural tube closure GO:0001843 58 26 0,000 0,04439232 0,05741156 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,04439232 0,05738118 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,04439232 0,05735084 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,04439232 0,05732052 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,04606042 0,059443 ! embryonic pattern specification GO:0009880 49 27 0,000 0,04606042 0,05941162 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,04606042 0,05938027 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,04606042 0,05934895 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,04606042 0,05931766 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,04606042 0,05928641 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,04606042 0,05925519 ! iron ion transport GO:0006826 65 27 0,000 0,04606042 0,059224 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,04606042 0,05919285 ! superoxide metabolic process GO:0006801 41 27 0,000 0,04606042 0,05916173 ! tube lumen formation GO:0035148 59 27 0,000 0,04606042 0,05913064 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,04606042 0,05909958 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,04606042 0,05906856 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,04606042 0,05903757 ! response to starvation GO:0042594 47 27 0,000 0,04606042 0,05900661 ! response to toxin GO:0009636 49 27 0,000 0,04606042 0,05897569 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,04606042 0,05894479 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,04606042 0,05891393 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,04606042 0,0588831 ! leukocyte proliferation GO:0070661 59 27 0,000 0,04606042 0,05885231 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,04606042 0,05882154 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,04772566 0,06091629 ! neuron fate commitment GO:0048663 52 28 0,000 0,04772566 0,06088448 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,04772566 0,06085271 ! protein amino acid acylation GO:0043543 59 28 0,000 0,04772566 0,06082096 ! circadian rhythm GO:0007623 56 28 0,000 0,04772566 0,06078925 ! dendrite development GO:0016358 67 28 0,000 0,04772566 0,06075757 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,04772566 0,06072593 ! fat cell differentiation GO:0045444 57 28 0,000 0,04772566 0,06069432 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,04772566 0,06066274 ! sperm motility GO:0030317 37 28 0,000 0,04772566 0,06063119 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,04772566 0,06059968 ! base-excision repair GO:0006284 41 28 0,000 0,04772566 0,0605682 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,04772566 0,06053675 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,04772566 0,06050534 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,04772566 0,06047395 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,04772566 0,0604426 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,04772566 0,06041129 ! glutathione metabolic process GO:0006749 42 28 0,000 0,04772566 0,06038 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,04772566 0,06034875 ! lipid oxidation GO:0034440 48 28 0,000 0,04772566 0,06031753 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,04772566 0,06028634 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,04772566 0,06025519 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,04938804 0,06232178 ! translational initiation GO:0006413 66 29 0,000 0,04938804 0,06228961 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,04938804 0,06225747 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,04938804 0,06222536 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,04938804 0,06219329 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,04938804 0,06216124 ! autophagy GO:0006914 47 29 0,000 0,04938804 0,06212923 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,04938804 0,06209726 ! primary neural tube formation GO:0014020 61 29 0,000 0,04938804 0,06206532 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,04938804 0,06203341 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,04938804 0,06200153 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,04938804 0,06196968 ! somitogenesis GO:0001756 52 29 0,000 0,04938804 0,06193787 ! synaptogenesis GO:0007416 46 29 0,000 0,04938804 0,06190609 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,04938804 0,06187435 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,04938804 0,06184263 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,04938804 0,06181095 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,04938804 0,0617793 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,05104756 0,06382251 ! phenol metabolic process GO:0018958 56 30 0,000 0,05104756 0,06378987 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,05104756 0,06375725 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,05104756 0,06372467 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,05104756 0,06369213 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,05104756 0,06365962 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,05104756 0,06362714 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,05104756 0,06359469 ! acute-phase response GO:0006953 50 30 0,000 0,05104756 0,06356228 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,05104756 0,0635299 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,05104756 0,06349755 ! myofibril assembly GO:0030239 50 30 0,000 0,05104756 0,06346524 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,05104756 0,06343295 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,05104756 0,06340071 ! cell fate determination GO:0001709 64 30 0,000 0,05104756 0,06336849 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,05104756 0,06333631 ! phospholipid transport GO:0015914 65 30 0,000 0,05104756 0,06330416 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,05104756 0,06327204 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,05104756 0,06323995 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,05104756 0,0632079 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,05104756 0,06317588 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,05104756 0,06314389 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,05104756 0,06311194 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,05270423 0,06512718 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,05270423 0,06509426 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,05270423 0,06506136 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,05270423 0,0650285 ! regulation of innate immune response GO:0045088 57 31 0,000 0,05270423 0,06499568 ! ovulation cycle process GO:0022602 55 31 0,000 0,05270423 0,06496288 ! peptide transport GO:0015833 60 31 0,000 0,05270423 0,06493012 ! male gonad development GO:0008584 56 31 0,000 0,05270423 0,0648974 ! iron ion homeostasis GO:0055072 60 31 0,000 0,05270423 0,0648647 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,05270423 0,06483204 ! detection of light stimulus GO:0009583 44 31 0,000 0,05270423 0,06479941 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,05270423 0,06476682 ! natural killer cell activation GO:0030101 50 31 0,000 0,05270423 0,06473426 ! ensheathment of neurons GO:0007272 64 31 0,000 0,05270423 0,06470173 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,05270423 0,06466923 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,05270423 0,06463677 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,05270423 0,06460433 ! eye morphogenesis GO:0048592 65 31 0,000 0,05270423 0,06457193 ! response to heat GO:0009408 54 31 0,000 0,05270423 0,06453957 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,05270423 0,06450723 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,05435806 0,06649811 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,05435806 0,06646483 ! collagen metabolic process GO:0032963 49 32 0,000 0,05435806 0,06643158 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,05435806 0,06639837 ! spindle organization GO:0007051 50 32 0,000 0,05435806 0,06636518 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,05435806 0,06633204 ! metanephros development GO:0001656 81 32 0,000 0,05435806 0,06629892 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,05435806 0,06626584 ! muscle cell development GO:0055001 52 32 0,000 0,05435806 0,06623279 ! mesoderm formation GO:0001707 73 32 0,000 0,05435806 0,06619977 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,05435806 0,06616678 ! ovulation cycle GO:0042698 57 32 0,000 0,05435806 0,06613383 ! peripheral nervous system development GO:0007422 68 32 0,000 0,05435806 0,06610091 ! BMP signaling pathway GO:0030509 71 32 0,000 0,05435806 0,06606803 ! hindbrain development GO:0030902 65 32 0,000 0,05435806 0,06603517 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,05435806 0,06600235 ! gene silencing GO:0016458 71 32 0,000 0,05435806 0,06596957 ! regulation of pH GO:0006885 56 33 0,000 0,05600904 0,06793947 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,05600904 0,06790575 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,05600904 0,06787207 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,05600904 0,06783842 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,05600904 0,0678048 ! response to ionizing radiation GO:0010212 74 33 0,000 0,05600904 0,06777122 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,05600904 0,06773767 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,05600904 0,06770415 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,05600904 0,06767067 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,05600904 0,06763722 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,05600904 0,0676038 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,05600904 0,06757042 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,05600904 0,06753706 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,05765719 0,06949014 ! glial cell differentiation GO:0010001 67 34 0,000 0,05765719 0,06945588 ! post-embryonic development GO:0009791 76 34 0,000 0,05765719 0,06942165 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,05765719 0,06938745 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,05765719 0,06935328 ! spliceosome assembly GO:0000245 75 34 0,000 0,05765719 0,06931915 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,05765719 0,06928506 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,05765719 0,06925099 ! formation of primary germ layer GO:0001704 76 34 0,000 0,05765719 0,06921696 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,05765719 0,06918297 ! adult locomotory behavior GO:0008344 62 34 0,000 0,05765719 0,069149 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,05930251 0,07108736 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,05930251 0,07105249 ! negative regulation of secretion GO:0051048 68 35 0,000 0,05930251 0,07101766 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,05930251 0,07098287 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,05930251 0,07094811 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,05930251 0,07091338 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,05930251 0,07087869 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,05930251 0,07084403 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,05930251 0,0708094 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,05930251 0,07077481 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,05930251 0,07074025 ! ceramide metabolic process GO:0006672 72 35 0,000 0,05930251 0,07070573 ! telencephalon development GO:0021537 81 35 0,000 0,05930251 0,07067124 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,05930251 0,07063678 ! placenta development GO:0001890 53 35 0,000 0,05930251 0,07060236 ! vesicle localization GO:0051648 70 35 0,000 0,05930251 0,07056797 ! regulation of muscle development GO:0048634 82 36 0,000 0,060945 0,07248717 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,060945 0,07245189 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,060945 0,07241665 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,060945 0,07238145 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,060945 0,07234628 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,060945 0,07231114 ! positive regulation of cell development GO:0010720 85 36 0,000 0,060945 0,07227604 ! protein targeting to membrane GO:0006612 75 36 0,000 0,060945 0,07224097 ! regulation of proteolysis GO:0030162 77 36 0,000 0,060945 0,07220594 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,060945 0,07217094 ! aerobic respiration GO:0009060 56 36 0,000 0,060945 0,07213597 ! cytokine production GO:0001816 68 36 0,000 0,060945 0,07210104 ! embryonic organ development GO:0048568 67 36 0,000 0,060945 0,07206614 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,060945 0,07203127 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,060945 0,07199644 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,06258467 0,07389771 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,06258467 0,07386201 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,06258467 0,07382634 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,06258467 0,07379071 ! sister chromatid segregation GO:0000819 65 37 0,000 0,06258467 0,07375512 ! odontogenesis GO:0042476 74 37 0,000 0,06258467 0,07371955 ! actomyosin structure organization GO:0031032 68 37 0,000 0,06258467 0,07368403 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,06258467 0,07364853 ! female gonad development GO:0008585 71 37 0,000 0,06258467 0,07361307 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,06258467 0,07357765 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,06258467 0,07354226 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,06258467 0,0735069 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,06422153 0,07539317 ! meiosis I GO:0007127 74 38 0,000 0,06422153 0,07535696 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,06422153 0,07532078 ! organic anion transport GO:0015711 82 38 0,000 0,06422153 0,07528464 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,06422153 0,07524853 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,06422153 0,07521246 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,06422153 0,07517642 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,06422153 0,07514042 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,06422153 0,07510445 ! regulation of protein stability GO:0031647 77 38 0,000 0,06422153 0,07506851 ! spermatid development GO:0007286 69 38 0,000 0,06422153 0,07503261 ! glycogen metabolic process GO:0005977 63 38 0,000 0,06422153 0,07499674 ! pigment metabolic process GO:0042440 87 38 0,000 0,06422153 0,07496091 ! neural tube formation GO:0001841 79 38 0,000 0,06422153 0,07492511 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,06585557 0,07679482 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,06585557 0,07675818 ! negative regulation of binding GO:0051100 71 39 0,000 0,06585557 0,07672158 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,06585557 0,07668501 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,06585557 0,07664848 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,06585557 0,07661198 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,06585557 0,07657551 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,06585557 0,07653908 ! glucan metabolic process GO:0044042 64 39 0,000 0,06585557 0,07650269 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,0674868 0,07836039 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,0674868 0,07832316 ! learning GO:0007612 82 40 0,000 0,0674868 0,07828597 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,0674868 0,07824882 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,0674868 0,0782117 ! mismatch repair GO:0006298 58 40 0,000 0,0674868 0,07817461 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,0674868 0,07813756 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,0674868 0,07810055 ! RNA export from nucleus GO:0006405 61 41 0,000 0,06911523 0,07994721 ! mRNA catabolic process GO:0006402 79 41 0,000 0,06911523 0,07990938 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,06911523 0,07987158 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,06911523 0,07983381 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,06911523 0,07979608 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,06911523 0,07975839 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,06911523 0,07972073 ! gliogenesis GO:0042063 91 41 0,000 0,06911523 0,07968311 ! feeding behavior GO:0007631 69 41 0,000 0,06911523 0,07964552 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,06911523 0,07960797 ! mesenchymal cell development GO:0014031 94 41 0,000 0,06911523 0,07957046 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,06911523 0,07953298 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,06911523 0,07949553 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,06911523 0,07945812 ! spermatid differentiation GO:0048515 73 41 0,000 0,06911523 0,07942075 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,06911523 0,07938341 ! RNA modification GO:0009451 64 41 0,000 0,06911523 0,07934611 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,07074087 0,08117423 ! ear morphogenesis GO:0042471 64 42 0,000 0,07074087 0,08113612 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,07074087 0,08109805 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,07074087 0,08106001 ! regulation of protein secretion GO:0050708 77 42 0,000 0,07074087 0,081022 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,07074087 0,08098404 ! cytokinesis GO:0000910 84 42 0,000 0,07074087 0,08094611 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,07074087 0,08090821 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,07236371 0,08272557 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,07236371 0,08268687 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,07236371 0,08264822 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,07236371 0,08260959 ! regulation of tube size GO:0035150 76 43 0,000 0,07236371 0,08257101 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,07236371 0,08253246 ! glucose transport GO:0015758 66 43 0,000 0,07236371 0,08249395 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,07236371 0,08245547 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,07236371 0,08241703 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,07236371 0,08237863 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,07236371 0,08234026 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,07236371 0,08230192 ! segmentation GO:0035282 78 43 0,000 0,07236371 0,08226363 ! ion transmembrane transport GO:0034220 79 43 0,000 0,07236371 0,08222536 ! neuron migration GO:0001764 85 43 0,000 0,07236371 0,08218714 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,07236371 0,08214895 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,07398376 0,08394906 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,07398376 0,08391008 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,07398376 0,08387115 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,07398376 0,08383224 ! hexose transport GO:0008645 68 44 0,000 0,07398376 0,08379338 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,07398376 0,08375455 ! striated muscle contraction GO:0006941 85 44 0,000 0,07398376 0,08371576 ! phagocytosis GO:0006909 105 44 0,000 0,07398376 0,083677 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,07398376 0,08363828 ! double-strand break repair GO:0006302 85 44 0,000 0,07398376 0,08359959 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,07560103 0,08538757 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,07560103 0,08534811 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,07560103 0,08530869 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,07560103 0,0852693 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,07560103 0,08522995 ! biopolymer methylation GO:0043414 91 45 0,000 0,07560103 0,08519064 ! B cell differentiation GO:0030183 124 45 0,000 0,07560103 0,08515136 ! female gamete generation GO:0007292 71 45 0,000 0,07560103 0,08511212 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,07560103 0,08507292 ! polyol metabolic process GO:0019751 77 45 0,000 0,07560103 0,08503375 ! developmental growth GO:0048589 88 45 0,000 0,07560103 0,08499462 ! maintenance of location in cell GO:0051651 101 45 0,000 0,07560103 0,08495552 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,07721551 0,08672989 ! glycolysis GO:0006096 71 46 0,000 0,07721551 0,08669003 ! leukocyte migration GO:0050900 75 46 0,000 0,07721551 0,08665021 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,07721551 0,08661042 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,07721551 0,08657067 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,07721551 0,08653096 ! pigmentation GO:0043473 103 46 0,000 0,07721551 0,08649129 ! neural tube development GO:0021915 91 47 0,000 0,07882723 0,08825615 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,07882723 0,08821572 ! positive regulation of defense response GO:0031349 88 48 0,000 0,08043617 0,08997508 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,08043617 0,0899339 ! mitochondrial transport GO:0006839 94 48 0,000 0,08043617 0,08989276 ! cellular component disassembly GO:0022411 89 48 0,000 0,08043617 0,08985166 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,08043617 0,08981059 ! endosome transport GO:0016197 127 48 0,000 0,08043617 0,08976956 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,08043617 0,08972857 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,08043617 0,08968762 ! male sex differentiation GO:0046661 93 48 0,000 0,08043617 0,0896467 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,08043617 0,08960582 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,08043617 0,08956498 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,08043617 0,08952418 ! methylation GO:0032259 97 48 0,000 0,08043617 0,08948341 ! response to calcium ion GO:0051592 94 49 0,000 0,08204235 0,09122871 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,08204235 0,0911872 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,08204235 0,09114573 ! JNK cascade GO:0007254 106 49 0,000 0,08204235 0,0911043 ! regulation of action potential GO:0001508 102 50 0,000 0,08364577 0,09284263 ! regulation of ion transport GO:0043269 86 50 0,000 0,08364577 0,09280046 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,08364577 0,09275834 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,08364577 0,09271625 ! activation of caspase activity GO:0006919 95 50 0,000 0,08364577 0,0926742 ! regulation of ossification GO:0030278 123 50 0,000 0,08364577 0,09263219 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,08364577 0,09259022 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,08364577 0,09254829 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,08364577 0,09250639 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,08364577 0,09246453 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,08364577 0,09242271 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,08524644 0,09414875 ! viral infectious cycle GO:0019058 104 51 0,000 0,08524644 0,09410621 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,08524644 0,09406371 ! peptide metabolic process GO:0006518 80 51 0,000 0,08524644 0,09402124 ! response to temperature stimulus GO:0009266 84 51 0,000 0,08524644 0,09397881 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,08524644 0,09393642 ! positive regulation of binding GO:0051099 88 52 0,000 0,08684435 0,09565408 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,08684435 0,09561097 ! Notch signaling pathway GO:0007219 111 52 0,000 0,08684435 0,0955679 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,08684435 0,09552487 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,08684435 0,09548188 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,08684435 0,09543893 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,08684435 0,09539602 ! excretion GO:0007588 87 52 0,000 0,08684435 0,09535314 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,08684435 0,09531031 ! histone modification GO:0016570 104 52 0,000 0,08684435 0,09526751 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,08684435 0,09522475 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,08684435 0,09518203 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,08684435 0,09513935 ! amino acid activation GO:0043038 98 52 0,000 0,08684435 0,0950967 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,08843952 0,09680006 ! inner ear development GO:0048839 89 53 0,000 0,08843952 0,09675671 ! chromatin remodeling GO:0006338 122 53 0,000 0,08843952 0,0967134 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,08843952 0,09667013 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,08843952 0,09662689 ! synapse organization GO:0050808 102 53 0,000 0,08843952 0,0965837 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,09003194 0,09827883 ! regulation of translational initiation GO:0006446 87 54 0,000 0,09003194 0,09823494 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,09003194 0,09819108 ! neuromuscular process GO:0050905 107 54 0,000 0,09003194 0,09814727 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,09003194 0,09810349 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,09003194 0,09805975 ! covalent chromatin modification GO:0016569 115 54 0,000 0,09003194 0,09801606 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,09003194 0,0979724 ! regulation of cell shape GO:0008360 142 54 0,000 0,09003194 0,09792878 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,09003194 0,09788519 ! RNA catabolic process GO:0006401 103 55 0,000 0,09162163 0,09956923 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,09162163 0,09952496 ! cell recognition GO:0008037 98 55 0,000 0,09162163 0,09948073 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,09162163 0,09943653 ! cell maturation GO:0048469 107 55 0,000 0,09162163 0,09939238 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,09162163 0,09934826 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,09320858 0,10102421 ! glucose catabolic process GO:0006007 88 56 0,000 0,09320858 0,10097941 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,09320858 0,10093465 ! RNA elongation GO:0006354 90 56 0,000 0,09320858 0,10088993 ! chloride transport GO:0006821 102 57 0,000 0,09479281 0,10255927 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,09479281 0,10251387 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,09479281 0,10246851 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 0,000 0,09479281 0,10242319 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,09637432 0,10408596 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,09637432 0,10403997 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,09637432 0,10399402 ! aging GO:0007568 112 58 0,000 0,09637432 0,1039481 ! gastrulation GO:0007369 122 58 0,000 0,09637432 0,10390223 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,09637432 0,1038564 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,09637432 0,10381061 ! maintenance of location GO:0051235 124 58 0,000 0,09637432 0,10376485 ! nuclear export GO:0051168 110 59 0,000 0,0979531 0,10541825 ! establishment of organelle localization GO:0051656 122 59 0,000 0,0979531 0,10537183 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,09952917 0,10702015 ! DNA catabolic process GO:0006308 94 60 0,000 0,09952917 0,10697306 ! regulation of endocytosis GO:0030100 104 60 0,000 0,09952917 0,10692602 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,09952917 0,10687902 ! adult behavior GO:0030534 104 60 0,000 0,09952917 0,10683206 ! kidney development GO:0001822 133 60 0,000 0,09952917 0,10678514 ! positive regulation of secretion GO:0051047 110 61 0,000 0,10110254 0,10842559 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,10110254 0,10837801 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,10110254 0,10833048 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,10110254 0,10828299 ! regulation of heart contraction GO:0008016 123 61 0,000 0,10110254 0,10823554 ! camera-type eye development GO:0043010 126 61 0,000 0,10110254 0,10818813 ! proton transport GO:0015992 117 61 0,000 0,10110254 0,10814076 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,10267319 0,1097727 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,10267319 0,10972468 ! tRNA processing GO:0008033 102 62 0,000 0,10267319 0,1096767 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,10267319 0,10962876 ! regulation of mitosis GO:0007088 112 63 0,000 0,10424115 0,11125432 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,10424115 0,11120573 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,10424115 0,11115719 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,10424115 0,1111087 ! hydrogen transport GO:0006818 121 64 0,000 0,10580641 0,1127279 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,10580641 0,11267876 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,10580641 0,11262966 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,10736898 0,11424322 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,10736898 0,11419348 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,10736898 0,11414379 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,10736898 0,11409414 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,10736898 0,11404453 ! ear development GO:0043583 114 66 0,000 0,10892887 0,11565112 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,10892887 0,11560088 ! gonad development GO:0008406 115 66 0,000 0,10892887 0,11555068 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,10892887 0,11550053 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,11048607 0,11710085 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,11048607 0,11705007 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,11048607 0,11699933 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,11048607 0,11694864 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,11048607 0,11689799 ! secondary metabolic process GO:0019748 125 67 0,000 0,11048607 0,11684739 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,11048607 0,11679683 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,11204059 0,11838891 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,11204059 0,11833773 ! hexose catabolic process GO:0019320 113 68 0,000 0,11204059 0,11828659 ! extracellular matrix organization GO:0030198 146 68 0,000 0,11204059 0,11823549 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,11204059 0,11818444 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,11204059 0,11813343 ! adaptive immune response GO:0002250 126 68 0,000 0,11204059 0,11808247 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,11204059 0,11803155 ! negative regulation of cell size GO:0045792 144 69 0,000 0,11359244 0,1196148 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,11359244 0,11956327 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,11359244 0,11951177 ! urogenital system development GO:0001655 149 69 0,000 0,11359244 0,11946033 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,11359244 0,11940892 ! developmental maturation GO:0021700 128 69 0,000 0,11359244 0,11935757 ! single fertilization GO:0007338 83 69 0,000 0,11359244 0,11930625 ! cell redox homeostasis GO:0045454 114 70 0,000 0,11514163 0,12088139 ! germ cell development GO:0007281 133 70 0,000 0,11514163 0,12082947 ! activation of immune response GO:0002253 120 70 0,000 0,11514163 0,12077759 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,11514163 0,12072575 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,11668815 0,12229478 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,11668815 0,12224234 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,11668815 0,12218995 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,11668815 0,12213759 ! carbohydrate transport GO:0008643 114 72 0,000 0,11823201 0,12370055 ! B cell activation GO:0042113 179 72 0,000 0,11823201 0,1236476 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,11823201 0,12359469 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,11823201 0,12354183 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,11823201 0,12348901 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,11823201 0,12343624 ! humoral immune response GO:0006959 115 73 0,000 0,11977321 0,12499186 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,11977321 0,12493849 ! acute inflammatory response GO:0002526 118 74 0,000 0,12131177 0,12648939 ! amino acid transport GO:0006865 148 74 0,000 0,12131177 0,12643543 ! regulation of caspase activity GO:0043281 136 74 0,000 0,12131177 0,12638151 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,12131177 0,12632764 ! organelle localization GO:0051640 155 74 0,000 0,12131177 0,12627381 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,12284767 0,12781809 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,12284767 0,12776367 ! reproductive structure development GO:0048608 131 75 0,000 0,12284767 0,1277093 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,12284767 0,12765498 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,12284767 0,12760071 ! eye development GO:0001654 155 75 0,000 0,12284767 0,12754648 ! axon guidance GO:0007411 162 75 0,000 0,12284767 0,1274923 ! rhythmic process GO:0048511 142 75 0,000 0,12284767 0,12743816 ! learning or memory GO:0007611 161 76 0,000 0,12438094 0,12897395 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,12438094 0,12891924 ! regulation of blood pressure GO:0008217 134 76 0,000 0,12438094 0,12886456 ! amine catabolic process GO:0009310 136 77 0,000 0,12591157 0,13039507 ! neurotransmitter transport GO:0006836 142 77 0,000 0,12591157 0,13033982 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,12591157 0,13028461 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,12591157 0,13022945 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,12591157 0,13017434 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,12591157 0,13011928 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,12591157 0,13006426 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,12743957 0,13158701 ! antigen processing and presentation GO:0019882 117 78 0,000 0,12743957 0,13153142 ! fertilization GO:0009566 99 78 0,000 0,12743957 0,13147587 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,12896494 0,13299339 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,12896494 0,13293727 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,12896494 0,13288121 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,12896494 0,13282519 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,13048768 0,13433688 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,13048768 0,13428029 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,13048768 0,13422375 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,13048768 0,13416726 ! meiosis GO:0007126 143 81 0,000 0,13200781 0,13567315 GO:0051327|M phase of meiotic cell cycle, ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,13200781 0,1356161 ! protein import into nucleus GO:0006606 174 82 0,000 0,13352532 0,13711743 ! meiotic cell cycle GO:0051321 144 82 0,000 0,13352532 0,13705981 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,13504022 0,1385566 ! exocytosis GO:0006887 153 83 0,000 0,13504022 0,13849843 ! response to drug GO:0042493 149 83 0,000 0,13504022 0,13844031 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,13504022 0,13838224 ! nuclear import GO:0051170 177 83 0,000 0,13504022 0,13832422 ! inorganic anion transport GO:0015698 156 83 0,000 0,13504022 0,13826625 ! response to metal ion GO:0010038 158 84 0,000 0,13655252 0,1397561 ! response to nutrient GO:0007584 135 84 0,000 0,13655252 0,13969757 ! digestion GO:0007586 130 84 0,000 0,13655252 0,1396391 ! regulation of ligase activity GO:0051340 147 84 0,000 0,13655252 0,13958067 ! negative regulation of transport GO:0051051 164 85 0,000 0,13806221 0,14106482 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,13806221 0,14100585 ! negative regulation of growth GO:0045926 168 85 0,000 0,13806221 0,14094692 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,13806221 0,14088805 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,13806221 0,14082922 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,13806221 0,14077044 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,13956931 0,14224773 ! regulation of lyase activity GO:0051339 169 86 0,000 0,13956931 0,14218842 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,14107381 0,14366124 ! mitochondrion organization GO:0007005 159 87 0,000 0,14107381 0,14360138 ! alcohol catabolic process GO:0046164 142 87 0,000 0,14107381 0,14354158 ! nucleosome assembly GO:0006334 126 87 0,000 0,14107381 0,14348182 ! cellular respiration GO:0045333 143 88 0,000 0,14257573 0,14494902 ! amine biosynthetic process GO:0009309 146 88 0,000 0,14257573 0,14488873 ! sensory perception of smell GO:0007608 117 88 0,000 0,14257573 0,14482848 ! chromatin assembly GO:0031497 128 88 0,000 0,14257573 0,14476829 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,14257573 0,14470814 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,14407506 0,14616917 ! regulation of DNA binding GO:0051101 167 89 0,000 0,14407506 0,1461085 ! tube morphogenesis GO:0035239 194 89 0,000 0,14407506 0,14604787 ! cellular defense response GO:0006968 123 89 0,000 0,14407506 0,1459873 ! protein localization in nucleus GO:0034504 192 89 0,000 0,14407506 0,14592677 ! regulation of neurological system process GO:0031644 175 89 0,000 0,14407506 0,1458663 ! response to inorganic substance GO:0010035 173 90 0,000 0,14557181 0,1473206 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,14557181 0,1472596 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,14557181 0,14719865 ! response to unfolded protein GO:0006986 139 90 0,000 0,14557181 0,14713775 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,14557181 0,1470769 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,14706599 0,1485251 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,14706599 0,14846372 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,14855759 0,14990756 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,14855759 0,14984567 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,15004663 0,15128515 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,15004663 0,15122274 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,15004663 0,15116038 ! vitamin metabolic process GO:0006766 153 93 0,000 0,15004663 0,15109807 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,15153311 0,15253209 ! female pregnancy GO:0007565 166 94 0,000 0,15153311 0,15246927 ! sterol metabolic process GO:0016125 166 94 0,000 0,15153311 0,1524065 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,15153311 0,15234378 ! regulation of defense response GO:0031347 171 95 0,000 0,15301703 0,15377236 ! nucleosome organization GO:0034728 143 95 0,000 0,15301703 0,15370913 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,15301703 0,15364595 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,15301703 0,15358283 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,15301703 0,15351976 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,15301703 0,15345674 ! sex differentiation GO:0007548 171 96 0,000 0,1544984 0,15487878 ! response to protein stimulus GO:0051789 158 96 0,000 0,1544984 0,15481525 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,15597721 0,15623302 ! transcription initiation GO:0006352 171 97 0,000 0,15597721 0,15616899 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,15745349 0,15758249 ! positive regulation of immune response GO:0050778 175 100 0,000 0,16039841 0,1604641 ! hormone metabolic process GO:0042445 171 100 0,000 0,16039841 0,16039841