pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1013-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein import into nucleus, translocation GO:0000060 46 24 2,000 1,199E-05 0,02884163 ! protein import into nucleus GO:0006606 158 80 3,000 1,526E-05 0,01835864 ! nuclear import GO:0051170 161 81 3,000 1,603E-05 0,01285715 ! protein localization in nucleus GO:0034504 176 87 3,000 2,127E-05 0,01279475 ! DNA damage checkpoint GO:0000077 71 33 2,000 3,193E-05 0,01536593 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,384E-05 0,01356838 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,384E-05 0,01163004 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 3,384E-05 0,01017628 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,384E-05 9,046E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,384E-05 8,141E-03 ! DNA integrity checkpoint GO:0031570 75 36 2,000 4,162E-05 9,104E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 4,162E-05 8,346E-03 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 4,905E-05 9,078E-03 ! male meiosis GO:0007140 7 6 1,000 5,069E-05 8,712E-03 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 1,000 5,069E-05 8,131E-03 ! phototransduction, visible light GO:0007603 9 6 1,000 5,069E-05 7,623E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 5,069E-05 7,175E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 7,089E-05 9,475E-03 ! SMAD protein complex assembly GO:0007183 12 7 1,000 7,089E-05 8,976E-03 ! mRNA stabilization GO:0048255 18 7 1,000 7,089E-05 8,528E-03 GO:0043489|RNA stabilization, ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 7,089E-05 8,122E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 7,089E-05 7,752E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 7,089E-05 7,415E-03 ! response to tumor cell GO:0002347 13 7 1,000 7,089E-05 7,106E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 9,44E-05 9,085E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 9,44E-05 8,736E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 9,44E-05 8,412E-03 ! ER overload response GO:0006983 12 8 1,000 9,44E-05 8,112E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 9,44E-05 7,832E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 9,44E-05 7,571E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 9,44E-05 7,327E-03 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,212E-04 9,115E-03 ! motor axon guidance GO:0008045 16 9 1,000 1,212E-04 8,839E-03 ! response to UV GO:0009411 104 53 2,000 1,335E-04 9,45E-03 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 1,514E-04 0,01040466 ! lung alveolus development GO:0048286 26 10 1,000 1,514E-04 0,01011564 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,514E-04 9,842E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 1,514E-04 9,583E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,514E-04 9,338E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,514E-04 9,104E-03 ! localization within membrane GO:0051668 20 10 1,000 1,514E-04 8,882E-03 ! regulation of DNA replication GO:0006275 101 56 2,000 1,574E-04 9,017E-03 ! positive regulation of cell migration GO:0030335 126 57 2,000 1,659E-04 9,284E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,848E-04 0,01010356 ! blood vessel remodeling GO:0001974 29 11 1,000 1,848E-04 9,879E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,848E-04 9,664E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,848E-04 9,459E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,848E-04 9,262E-03 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 1,933E-04 9,491E-03 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 2,215E-04 0,01065662 GO:0050927|positive regulation of positive chemotaxis, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,215E-04 0,01044767 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 2,234E-04 0,01033714 ! positive regulation of cell motion GO:0051272 146 64 2,000 2,341E-04 0,0106269 ! response to X-ray GO:0010165 25 13 1,000 2,614E-04 0,01164736 ! regulation of cellular pH GO:0030641 22 13 1,000 2,614E-04 0,01143559 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,614E-04 0,01123138 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,614E-04 0,01103434 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 2,801E-04 0,01161942 ! cell cycle checkpoint GO:0000075 137 69 2,000 2,924E-04 0,01192598 ! response to gamma radiation GO:0010332 28 14 1,000 3,046E-04 0,01221513 ! protein-chromophore linkage GO:0018298 19 14 1,000 3,046E-04 0,01201488 ! regulation of RNA stability GO:0043487 32 14 1,000 3,046E-04 0,01182109 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 3,046E-04 0,01163346 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,511E-04 0,01319771 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 3,511E-04 0,01299467 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,511E-04 0,01279778 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 4,007E-04 0,01439054 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 4,007E-04 0,01417891 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,007E-04 0,01397342 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,007E-04 0,0137738 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,536E-04 0,01537208 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 4,536E-04 0,01515858 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,536E-04 0,01495093 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 5,69E-04 0,01850033 ! G1 phase GO:0051318 40 19 1,000 5,69E-04 0,01825366 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 6,315E-04 0,0199911 ! cellular response to starvation GO:0009267 33 20 1,000 6,315E-04 0,01973148 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 6,315E-04 0,01947851 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 6,315E-04 0,01923195 ! cell aging GO:0007569 44 21 1,000 6,971E-04 0,02096562 ! positive regulation of locomotion GO:0040017 39 21 1,000 6,971E-04 0,02070679 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 7,466E-04 0,02190752 ! regulation of chemotaxis GO:0050920 40 22 1,000 7,659E-04 0,0222021 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 7,659E-04 0,02193779 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 7,659E-04 0,0216797 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 7,932E-04 0,02219219 ! interphase GO:0051325 213 98 2,000 8,172E-04 0,02260016 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 8,379E-04 0,02290762 ! regulation of behavior GO:0050795 43 24 1,000 9,129E-04 0,02467988 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 9,129E-04 0,02440566 ! protein tetramerization GO:0051262 52 24 1,000 9,129E-04 0,02413746 ! vasculogenesis GO:0001570 46 25 1,000 9,911E-04 0,02592026 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 9,911E-04 0,02564155 ! response to starvation GO:0042594 42 25 1,000 9,911E-04 0,02536876 ! negative regulation of cell development GO:0010721 73 25 1,000 9,911E-04 0,02510172 GO:0050768|negative regulation of neurogenesis, ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 9,911E-04 0,02484025 ! phototransduction GO:0007602 33 25 1,000 9,911E-04 0,02458416 ! negative regulation of DNA replication GO:0008156 42 25 1,000 9,911E-04 0,0243333 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 9,911E-04 0,02408751 ! cellular response to nutrient levels GO:0031669 41 25 1,000 9,911E-04 0,02384664 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 1,072E-03 0,02554759 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 1,157E-03 0,02728833 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 1,157E-03 0,02702339 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 1,157E-03 0,02676355 ! mitochondrial membrane organization GO:0007006 57 27 1,000 1,157E-03 0,02650866 ! base-excision repair GO:0006284 41 27 1,000 1,157E-03 0,02625858 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 1,000 1,244E-03 0,0279808 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,244E-03 0,02772172 ! regulation of pH GO:0006885 43 29 1,000 1,335E-03 0,02946686 ! detection of light stimulus GO:0009583 38 29 1,000 1,335E-03 0,02919898 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 1,335E-03 0,02893593 ! response to ionizing radiation GO:0010212 65 32 1,000 1,625E-03 0,03490962 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 1,728E-03 0,03678912 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 1,942E-03 0,04099597 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 1,942E-03 0,04063949 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 1,942E-03 0,04028915 ! calcium-mediated signaling GO:0019722 62 35 1,000 1,942E-03 0,03994479 ! tissue remodeling GO:0048771 76 37 1,000 2,169E-03 0,04422692 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 2,169E-03 0,04385527 ! T cell differentiation GO:0030217 81 41 1,000 2,658E-03 0,0532916 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 2,92E-03 0,05806237 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 2,92E-03 0,05758645 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 2,92E-03 0,05711826 ! double-strand break repair GO:0006302 81 44 1,000 3,055E-03 0,05928503 ! B cell differentiation GO:0030183 107 44 1,000 3,055E-03 0,05881075 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 3,194E-03 0,06098506 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 3,194E-03 0,06050487 ! cell growth GO:0016049 84 45 1,000 3,194E-03 0,06003217 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 3,335E-03 0,06220035 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 3,335E-03 0,06172188 ! vascular process in circulatory system GO:0003018 80 47 1,000 3,479E-03 0,06389693 ! positive regulation of cell cycle GO:0045787 89 48 1,000 3,626E-03 0,06609129 ! mitochondrial transport GO:0006839 82 48 1,000 3,626E-03 0,06559436 ! activation of caspase activity GO:0006919 84 48 1,000 3,626E-03 0,06510485 ! detection of abiotic stimulus GO:0009582 74 49 1,000 3,776E-03 0,06729242 ! chromatin remodeling GO:0006338 109 51 1,000 4,084E-03 0,07224888 ! regulation of cell shape GO:0008360 125 51 1,000 4,084E-03 0,07172152 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 4,403E-03 0,07677106 ! activation of phospholipase C activity GO:0007202 103 54 1,000 4,567E-03 0,07905623 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 1,000 4,734E-03 0,08135675 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 4,734E-03 0,08077976 ! aging GO:0007568 103 55 1,000 4,734E-03 0,08021088 ! nucleotide-excision repair GO:0006289 83 56 1,000 4,903E-03 0,08250189 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 5,076E-03 0,08480738 ! regulation of bone remodeling GO:0046850 137 57 1,000 5,076E-03 0,0842225 ! regulation of phospholipase activity GO:0010517 106 57 1,000 5,076E-03 0,08364564 ! regulation of tissue remodeling GO:0034103 140 58 1,000 5,251E-03 0,0859415 ! positive regulation of lipase activity GO:0060193 108 58 1,000 5,251E-03 0,08536081 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 5,609E-03 0,09057385 ! regulation of homeostatic process GO:0032844 134 62 1,000 5,978E-03 0,09589255 ! detection of external stimulus GO:0009581 91 63 1,000 6,167E-03 0,09826398 ! negative regulation of cell growth GO:0030308 132 67 1,000 6,949E-03 0,10998988 ! lung development GO:0030324 144 67 1,000 6,949E-03 0,10927099 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 6,949E-03 0,10856144 ! adaptive immune response GO:0002250 119 67 1,000 6,949E-03 0,10786104 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of lipase activity GO:0060191 130 68 1,000 7,151E-03 0,11028628 ! negative regulation of cell size GO:0045792 134 69 1,000 7,355E-03 0,11272119 ! respiratory tube development GO:0030323 150 70 1,000 7,563E-03 0,11516545 ! B cell activation GO:0042113 160 71 1,000 7,773E-03 0,11761871 ! regulation of caspase activity GO:0043281 122 72 1,000 7,985E-03 0,12008066 ! respiratory system development GO:0060541 153 72 1,000 7,985E-03 0,11933482 ! axon guidance GO:0007411 139 73 1,000 8,201E-03 0,1217945 ! meiosis GO:0007126 121 74 1,000 8,418E-03 0,12426234 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 8,418E-03 0,12350464 ! meiotic cell cycle GO:0051321 122 75 1,000 8,639E-03 0,12596992 ! lymphocyte differentiation GO:0030098 167 75 1,000 8,639E-03 0,12521106 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 9,263E-03 0,13345632 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 9,263E-03 0,13266194 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 9,263E-03 0,13187695 ! positive regulation of helicase activity GO:0051096 11 5 0,000 9,263E-03 0,13110121 ! neuron fate determination GO:0048664 7 5 0,000 9,263E-03 0,13033453 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,263E-03 0,12957678 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 9,263E-03 0,12882778 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 9,263E-03 0,12808739 ! polyol transport GO:0015791 12 5 0,000 9,263E-03 0,12735546 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 9,263E-03 0,12663185 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 9,263E-03 0,12591641 ! response to superoxide GO:0000303 10 5 0,000 9,263E-03 0,12520902 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 9,263E-03 0,12450953 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 9,263E-03 0,12381781 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 9,263E-03 0,12313373 ! female meiosis GO:0007143 7 5 0,000 9,263E-03 0,12245717 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 9,263E-03 0,12178801 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 9,263E-03 0,12112612 ! cobalt ion transport GO:0006824 11 5 0,000 9,263E-03 0,12047138 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 9,263E-03 0,11982368 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 9,263E-03 0,11918292 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 9,263E-03 0,11854896 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 9,263E-03 0,11792172 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 9,263E-03 0,11730108 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 9,263E-03 0,11668694 ! embryonic camera-type eye development GO:0031076 10 5 0,000 9,263E-03 0,11607919 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 9,263E-03 0,11547775 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 9,263E-03 0,1148825 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 9,263E-03 0,11429336 ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,263E-03 0,11371023 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 9,263E-03 0,11313302 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 9,263E-03 0,11256164 ! negative chemotaxis GO:0050919 14 5 0,000 9,263E-03 0,11199601 ! positive regulation of histone modification GO:0031058 5 5 0,000 9,263E-03 0,11143603 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 9,263E-03 0,11088162 ! sensory perception of bitter taste GO:0050913 7 5 0,000 9,263E-03 0,1103327 ! behavioral response to pain GO:0048266 9 5 0,000 9,263E-03 0,10978919 ! clathrin coat assembly GO:0048268 14 5 0,000 9,263E-03 0,10925101 ! Notch receptor processing GO:0007220 8 5 0,000 9,263E-03 0,10871807 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,263E-03 0,10819032 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 9,263E-03 0,10766766 ! micturition GO:0060073 9 5 0,000 9,263E-03 0,10715003 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 9,263E-03 0,10663735 ! copulation GO:0007620 9 5 0,000 9,263E-03 0,10612955 ! glial cell fate commitment GO:0021781 13 5 0,000 9,263E-03 0,10562657 ! protein maturation by protein folding GO:0022417 13 5 0,000 9,263E-03 0,10512833 ! spermidine metabolic process GO:0008216 7 5 0,000 9,263E-03 0,10463477 ! regulation of potassium ion transport GO:0043266 10 5 0,000 9,263E-03 0,10414582 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 9,263E-03 0,10366142 ! apoptotic cell clearance GO:0043277 20 5 0,000 9,263E-03 0,10318151 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 9,263E-03 0,10270602 ! lipoprotein particle clearance GO:0034381 10 5 0,000 9,263E-03 0,10223489 ! grooming behavior GO:0007625 6 5 0,000 9,263E-03 0,10176806 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 9,263E-03 0,10130548 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 9,263E-03 0,10084708 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,263E-03 0,10039282 ! response to protozoan GO:0001562 10 5 0,000 9,263E-03 0,09994262 ! positive regulation of glycolysis GO:0045821 14 5 0,000 9,263E-03 0,09949645 ! lymph vessel development GO:0001945 10 5 0,000 9,263E-03 0,09905425 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 9,263E-03 0,09861595 ! endochondral ossification GO:0001958 16 5 0,000 9,263E-03 0,09818152 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 9,263E-03 0,0977509 ! parathyroid gland development GO:0060017 13 5 0,000 9,263E-03 0,09732404 ! anagen GO:0042640 6 5 0,000 9,263E-03 0,09690089 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 9,263E-03 0,09648141 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 9,263E-03 0,09606554 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 9,263E-03 0,09565324 ! dorsal spinal cord development GO:0021516 7 5 0,000 9,263E-03 0,09524447 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 9,263E-03 0,09483917 ! sphingoid catabolic process GO:0046521 6 5 0,000 9,263E-03 0,09443731 ! skeletal myofibril assembly GO:0014866 10 5 0,000 9,263E-03 0,09403884 ! smooth muscle tissue development GO:0048745 28 5 0,000 9,263E-03 0,09364372 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 9,263E-03 0,09325191 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 9,263E-03 0,09286336 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 9,263E-03 0,09247803 ! cardiac muscle fiber development GO:0048739 10 5 0,000 9,263E-03 0,09209589 ! transepithelial chloride transport GO:0030321 9 5 0,000 9,263E-03 0,09171689 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 9,263E-03 0,09134101 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 9,263E-03 0,09096819 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 9,263E-03 0,0905984 ! neutrophil mediated immunity GO:0002446 7 5 0,000 9,263E-03 0,0902316 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 9,263E-03 0,08986776 ! histidine catabolic process GO:0006548 6 5 0,000 9,263E-03 0,08950685 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 9,263E-03 0,08914882 ! microvillus organization GO:0032528 7 5 0,000 9,263E-03 0,08879365 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 9,263E-03 0,08844129 ! L-serine biosynthetic process GO:0006564 6 5 0,000 9,263E-03 0,08809172 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 9,263E-03 0,0877449 ! tryptophan metabolic process GO:0006568 9 5 0,000 9,263E-03 0,08740081 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 9,263E-03 0,0870594 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 9,263E-03 0,08672064 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 9,263E-03 0,08638452 ! polyol catabolic process GO:0046174 7 5 0,000 9,263E-03 0,08605099 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 9,263E-03 0,08572002 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 9,263E-03 0,08539159 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 9,263E-03 0,08506567 ! muscle cell migration GO:0014812 8 5 0,000 9,263E-03 0,08474223 ! mitochondrial fission GO:0000266 8 5 0,000 9,263E-03 0,08442123 ! sister chromatid cohesion GO:0007062 12 5 0,000 9,263E-03 0,08410266 ! mRNA transcription GO:0009299 9 5 0,000 9,263E-03 0,08378649 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 9,263E-03 0,08347268 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 9,263E-03 0,08316121 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 9,263E-03 0,08285206 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 9,263E-03 0,0825452 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 9,263E-03 0,08224061 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 9,263E-03 0,08193825 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 9,263E-03 0,08163811 ! response to food GO:0032094 6 5 0,000 9,263E-03 0,08134017 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 9,263E-03 0,08104438 ! positive regulation of transporter activity GO:0032411 8 5 0,000 9,263E-03 0,08075074 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 9,263E-03 0,08045923 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,263E-03 0,0801698 ! paraxial mesoderm development GO:0048339 14 5 0,000 9,263E-03 0,07988246 ! forebrain neuron development GO:0021884 13 5 0,000 9,263E-03 0,07959716 ! lipoprotein catabolic process GO:0042159 11 5 0,000 9,263E-03 0,0793139 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 9,263E-03 0,07903264 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 9,263E-03 0,07875338 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,263E-03 0,07847608 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 9,263E-03 0,07820072 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 9,263E-03 0,07792729 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,263E-03 0,07765577 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 9,263E-03 0,07738613 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 9,263E-03 0,07711836 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 9,263E-03 0,07685243 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 9,263E-03 0,07658833 ! basic amino acid transport GO:0015802 11 5 0,000 9,263E-03 0,07632605 ! cellular glucose homeostasis GO:0001678 5 5 0,000 9,263E-03 0,07606555 ! early endosome to late endosome transport GO:0045022 12 5 0,000 9,263E-03 0,07580682 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,263E-03 0,07554985 ! depyrimidination GO:0045008 10 5 0,000 9,263E-03 0,07529461 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 9,263E-03 0,0750411 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,263E-03 0,07478928 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 9,263E-03 0,07453915 ! zinc ion homeostasis GO:0055069 8 5 0,000 9,263E-03 0,07429068 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 9,263E-03 0,07404387 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 9,263E-03 0,07379869 ! forebrain morphogenesis GO:0048853 13 5 0,000 9,263E-03 0,07355513 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 9,263E-03 0,07331318 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 9,263E-03 0,0730728 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 9,263E-03 0,072834 ! peptidyl-arginine modification GO:0018195 9 5 0,000 9,263E-03 0,07259676 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 9,263E-03 0,07236106 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,263E-03 0,07212688 ! response to arsenic GO:0046685 10 5 0,000 9,263E-03 0,07189421 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 9,263E-03 0,07166304 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 9,263E-03 0,07143335 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 9,263E-03 0,07120513 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 9,263E-03 0,07097836 ! response to cadmium ion GO:0046686 7 5 0,000 9,263E-03 0,07075303 ! bile acid biosynthetic process GO:0006699 6 5 0,000 9,263E-03 0,07052913 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 9,263E-03 0,07030664 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 9,263E-03 0,07008555 ! decidualization GO:0046697 11 5 0,000 9,263E-03 0,06986585 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 9,263E-03 0,06964752 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 9,263E-03 0,06943055 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 9,263E-03 0,06921492 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 9,263E-03 0,06900064 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 9,263E-03 0,06878767 ! base conversion or substitution editing GO:0016553 5 5 0,000 9,263E-03 0,06857602 ! neural tube patterning GO:0021532 7 5 0,000 9,263E-03 0,06836566 ! embryonic cleavage GO:0040016 6 5 0,000 9,263E-03 0,06815659 ! peroxisome fission GO:0016559 5 5 0,000 9,263E-03 0,0679488 ! histone demethylation GO:0016577 10 5 0,000 9,263E-03 0,06774227 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 9,263E-03 0,06753699 ! mitotic recombination GO:0006312 9 5 0,000 9,263E-03 0,06733295 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 9,263E-03 0,06713014 ! metaphase plate congression GO:0051310 7 5 0,000 9,263E-03 0,06692854 ! regulation of sterol transport GO:0032371 7 5 0,000 9,263E-03 0,06672816 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 9,263E-03 0,06652897 ! enteric nervous system development GO:0048484 8 5 0,000 9,263E-03 0,06633097 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 9,263E-03 0,06613414 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 9,263E-03 0,06593848 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 9,263E-03 0,06574397 ! muscle cell proliferation GO:0033002 11 5 0,000 9,263E-03 0,0655506 ! skeletal muscle regeneration GO:0043403 8 5 0,000 9,263E-03 0,06535837 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 9,263E-03 0,06516727 ! plasminogen activation GO:0031639 5 5 0,000 9,263E-03 0,06497728 ! B cell homeostasis GO:0001782 13 5 0,000 9,263E-03 0,06478839 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 9,263E-03 0,0646006 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 9,263E-03 0,06441389 ! metaphase GO:0051323 8 5 0,000 9,263E-03 0,06422826 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 9,263E-03 0,06404369 ! cellular response to nutrient GO:0031670 8 5 0,000 9,263E-03 0,06386019 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 9,263E-03 0,06367773 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 9,263E-03 0,06349631 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 9,263E-03 0,06331592 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 9,263E-03 0,06313656 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 9,263E-03 0,06295821 ! response to redox state GO:0051775 5 5 0,000 9,263E-03 0,06278086 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 9,263E-03 0,06260451 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 9,263E-03 0,06242915 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 9,263E-03 0,06225476 ! regulation of telomerase activity GO:0051972 6 5 0,000 9,263E-03 0,06208135 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,263E-03 0,0619089 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 9,263E-03 0,06173741 ! porphyrin catabolic process GO:0006787 12 5 0,000 9,263E-03 0,06156687 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 9,263E-03 0,06139726 ! striatum development GO:0021756 9 5 0,000 9,263E-03 0,06122859 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 9,263E-03 0,06106084 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 9,263E-03 0,060894 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 9,263E-03 0,06072808 ! glial cell migration GO:0008347 11 5 0,000 9,263E-03 0,06056306 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 9,263E-03 0,06039893 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 9,263E-03 0,06023569 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 9,263E-03 0,06007333 ! somatic stem cell maintenance GO:0035019 15 5 0,000 9,263E-03 0,05991184 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 9,263E-03 0,05975122 ! negative regulation of lipase activity GO:0060192 8 5 0,000 9,263E-03 0,05959146 ! neuroprotection GO:0043526 6 5 0,000 9,263E-03 0,05943255 ! neural plate development GO:0001840 8 5 0,000 9,263E-03 0,05927448 ! regulation of sensory perception GO:0051931 7 5 0,000 9,263E-03 0,05911726 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 9,263E-03 0,05896086 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 9,263E-03 0,05880529 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 9,263E-03 0,05865054 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 9,263E-03 0,0584966 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 9,263E-03 0,05834347 ! sequestering of calcium ion GO:0051208 7 5 0,000 9,263E-03 0,05819114 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 9,263E-03 0,0580396 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 9,263E-03 0,05788885 ! spindle assembly GO:0051225 6 5 0,000 9,263E-03 0,05773887 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 9,263E-03 0,05758968 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 9,263E-03 0,05744125 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 9,263E-03 0,05729359 ! drug metabolic process GO:0017144 6 5 0,000 9,263E-03 0,05714668 ! stem cell division GO:0017145 11 5 0,000 9,263E-03 0,05700053 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 9,263E-03 0,05685512 ! organ regeneration GO:0031100 7 5 0,000 9,263E-03 0,05671045 ! carnitine metabolic process GO:0009437 7 5 0,000 9,263E-03 0,05656651 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 9,263E-03 0,0564233 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 9,263E-03 0,05628082 ! protein oligomerization GO:0051259 139 78 1,000 9,315E-03 0,05645583 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 9,546E-03 0,05770828 ! regulation of peptidase activity GO:0052547 134 79 1,000 9,546E-03 0,05756365 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 9,546E-03 0,05741974 ! T cell activation GO:0042110 168 81 1,000 0,01001498 0,06008989 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01001498 0,05994041 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,01001498 0,05979168 ! response to drug GO:0042493 143 82 1,000 0,01025321 0,06106242 ! response to oxygen levels GO:0070482 176 83 1,000 0,01049394 0,06234179 ! negative regulation of growth GO:0045926 155 84 1,000 0,01073717 0,06362965 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01110567 0,06565173 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01110567 0,06549081 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01110567 0,06533069 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01110567 0,06517135 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01110567 0,06501278 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01110567 0,06485498 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01110567 0,06469795 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01110567 0,06454167 ! sleep GO:0030431 13 6 0,000 0,01110567 0,06438615 ! response to oxygen radical GO:0000305 11 6 0,000 0,01110567 0,06423138 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01110567 0,06407734 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01110567 0,06392405 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01110567 0,06377149 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01110567 0,06361965 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01110567 0,06346853 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01110567 0,06331813 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01110567 0,06316845 ! forebrain regionalization GO:0021871 8 6 0,000 0,01110567 0,06301946 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01110567 0,06287118 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01110567 0,0627236 ! response to zinc ion GO:0010043 9 6 0,000 0,01110567 0,0625767 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01110567 0,0624305 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01110567 0,06228497 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01110567 0,06214012 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01110567 0,06199595 ! malate metabolic process GO:0006108 11 6 0,000 0,01110567 0,06185244 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01110567 0,06170959 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 15 6 0,000 0,01110567 0,0615674 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01110567 0,06142587 ! opsonization GO:0008228 8 6 0,000 0,01110567 0,06128498 ! mating behavior GO:0007617 7 6 0,000 0,01110567 0,06114474 ! neuron remodeling GO:0016322 15 6 0,000 0,01110567 0,06100514 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01110567 0,06086618 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01110567 0,06072785 ! equilibrioception GO:0050957 14 6 0,000 0,01110567 0,06059014 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01110567 0,06045306 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01110567 0,0603166 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01110567 0,06018075 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01110567 0,06004551 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01110567 0,05991088 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01110567 0,05977685 ! toxin metabolic process GO:0009404 11 6 0,000 0,01110567 0,05964342 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01110567 0,05951058 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01110567 0,05937834 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01110567 0,05924668 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01110567 0,0591156 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01110567 0,0589851 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01110567 0,05885518 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01110567 0,05872583 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01110567 0,05859704 ! thymic T cell selection GO:0045061 12 6 0,000 0,01110567 0,05846882 ! protein lipoylation GO:0009249 10 6 0,000 0,01110567 0,05834116 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01110567 0,05821406 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01110567 0,05808751 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01110567 0,0579615 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01110567 0,05783604 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01110567 0,05771113 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01110567 0,05758675 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01110567 0,05746291 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01110567 0,0573396 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01110567 0,05721681 ! hyperosmotic response GO:0006972 9 6 0,000 0,01110567 0,05709456 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01110567 0,05697282 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01110567 0,0568516 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01110567 0,0567309 ! urea metabolic process GO:0019627 7 6 0,000 0,01110567 0,0566107 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01110567 0,05649102 ! neutrophil activation GO:0042119 8 6 0,000 0,01110567 0,05637184 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01110567 0,05625316 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01110567 0,05613498 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01110567 0,0560173 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01110567 0,05590011 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01110567 0,05578341 ! neuron apoptosis GO:0051402 9 6 0,000 0,01110567 0,05566719 ! nucleoside salvage GO:0043174 9 6 0,000 0,01110567 0,05555146 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01110567 0,05543621 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01110567 0,05532143 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01110567 0,05520713 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01110567 0,0550933 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01110567 0,05497994 ! carnitine transport GO:0015879 10 6 0,000 0,01110567 0,05486705 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01110567 0,05475462 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01110567 0,05464264 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01110567 0,05453113 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01110567 0,05442007 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01110567 0,05430946 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01110567 0,0541993 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01110567 0,05408958 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01110567 0,05398031 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01110567 0,05387148 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01110567 0,05376308 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01110567 0,05365513 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01110567 0,0535476 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01110567 0,05344051 ! neural nucleus development GO:0048857 14 6 0,000 0,01110567 0,05333384 ! response to UV-C GO:0010225 11 6 0,000 0,01110567 0,05322759 ! astrocyte development GO:0014002 15 6 0,000 0,01110567 0,05312177 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01110567 0,05301637 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01110567 0,05291139 ! interaction with symbiont GO:0051702 13 6 0,000 0,01110567 0,05280682 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01110567 0,05270267 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01110567 0,05259892 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01110567 0,05249558 ! response to copper ion GO:0046688 10 6 0,000 0,01110567 0,05239265 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01110567 0,05229012 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01110567 0,05218799 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01110567 0,05208626 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01110567 0,05198493 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01110567 0,05188399 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01110567 0,05178344 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01110567 0,05168327 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01110567 0,0515835 ! hair follicle maturation GO:0048820 7 6 0,000 0,01110567 0,05148411 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01110567 0,0513851 ! Schwann cell development GO:0014044 15 6 0,000 0,01110567 0,05128647 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01110567 0,05118822 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01110567 0,05109035 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01110567 0,05099285 ! subpallium development GO:0021544 10 6 0,000 0,01110567 0,05089572 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01110567 0,05079896 ! histone ubiquitination GO:0016574 8 6 0,000 0,01110567 0,05070257 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01110567 0,05060654 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01110567 0,05051087 ! G2 phase GO:0051319 16 6 0,000 0,01110567 0,05041557 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01110567 0,05032063 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01110567 0,05022604 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01110567 0,05013181 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01110567 0,05003793 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01110567 0,0499444 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01110567 0,04985122 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01110567 0,04975838 ! receptor internalization GO:0031623 10 6 0,000 0,01110567 0,0496659 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01110567 0,04957375 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01110567 0,04948195 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01110567 0,04939049 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01110567 0,04929936 ! protein deubiquitination GO:0016579 14 6 0,000 0,01110567 0,04920857 ! protein destabilization GO:0031648 9 6 0,000 0,01110567 0,04911811 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01110567 0,04902799 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01110567 0,04893819 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01110567 0,04884872 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01110567 0,04875958 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01110567 0,04867077 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01110567 0,04858228 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01110567 0,04849411 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01110567 0,04840625 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01110567 0,04831872 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01110567 0,0482315 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01110567 0,0481446 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01110567 0,04805801 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01110567 0,04797173 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01110567 0,04788576 ! catecholamine transport GO:0051937 9 6 0,000 0,01110567 0,04780009 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01110567 0,04771474 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01110567 0,04762968 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01110567 0,04754493 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01110567 0,04746048 ! maternal placenta development GO:0001893 12 6 0,000 0,01110567 0,04737633 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01110567 0,04729248 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01110567 0,04720893 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01110567 0,04712567 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01110567 0,0470427 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01110567 0,04696002 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01110567 0,04687764 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01110567 0,04679554 ! mitochondrion organization GO:0007005 148 86 1,000 0,01123109 0,04724126 ! cellular defense response GO:0006968 114 89 1,000 0,01199045 0,05034734 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,01199045 0,05025963 ! ossification GO:0001503 188 90 1,000 0,01224847 0,05125184 ! bone development GO:0060348 189 91 1,000 0,01250891 0,05225075 ! tRNA transcription GO:0009304 14 7 0,000 0,01294481 0,05397782 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01294481 0,05388443 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01294481 0,05379137 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01294481 0,05369862 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01294481 0,0536062 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01294481 0,05351409 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01294481 0,0534223 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01294481 0,05333083 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01294481 0,05323966 ! prostate gland development GO:0030850 13 7 0,000 0,01294481 0,05314881 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01294481 0,05305827 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01294481 0,05296803 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01294481 0,0528781 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01294481 0,05278848 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01294481 0,05269916 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01294481 0,05261014 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01294481 0,05252142 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01294481 0,052433 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01294481 0,05234488 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01294481 0,05225705 ! glycolipid transport GO:0046836 10 7 0,000 0,01294481 0,05216952 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01294481 0,05208228 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01294481 0,05199533 ! neuron adhesion GO:0007158 12 7 0,000 0,01294481 0,05190867 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01294481 0,0518223 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01294481 0,05173622 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01294481 0,05165042 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01294481 0,0515649 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01294481 0,05147967 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01294481 0,05139472 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01294481 0,05131005 ! pericardium development GO:0060039 14 7 0,000 0,01294481 0,05122566 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01294481 0,05114155 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01294481 0,05105771 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01294481 0,05097414 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01294481 0,05089085 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01294481 0,05080783 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01294481 0,05072509 ! lipoprotein transport GO:0042953 14 7 0,000 0,01294481 0,05064261 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01294481 0,05056039 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01294481 0,05047845 ! rhythmic behavior GO:0007622 15 7 0,000 0,01294481 0,05039677 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01294481 0,05031535 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01294481 0,0502342 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01294481 0,0501533 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01294481 0,05007267 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01294481 0,0499923 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01294481 0,04991218 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01294481 0,04983232 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01294481 0,04975272 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01294481 0,04967337 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01294481 0,04959427 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01294481 0,04951543 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01294481 0,04943683 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01294481 0,04935848 ! spinal cord patterning GO:0021511 13 7 0,000 0,01294481 0,04928038 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01294481 0,04920253 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01294481 0,04912492 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01294481 0,04904756 ! adrenal gland development GO:0030325 17 7 0,000 0,01294481 0,04897044 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01294481 0,04889357 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01294481 0,04881693 ! ovulation GO:0030728 9 7 0,000 0,01294481 0,04874054 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01294481 0,04866438 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01294481 0,04858846 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01294481 0,04851278 ! microtubule nucleation GO:0007020 20 7 0,000 0,01294481 0,04843733 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01294481 0,04836212 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01294481 0,04828714 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01294481 0,04821239 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01294481 0,04813787 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01294481 0,04806358 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01294481 0,04798953 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01294481 0,0479157 ! galactose metabolic process GO:0006012 13 7 0,000 0,01294481 0,04784209 ! vesicle fusion GO:0006906 17 7 0,000 0,01294481 0,04776872 ! response to dietary excess GO:0002021 8 7 0,000 0,01294481 0,04769556 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01294481 0,04762263 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01294481 0,04754993 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01294481 0,04747744 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01294481 0,04740518 ! organ growth GO:0035265 15 7 0,000 0,01294481 0,04733313 ! purine salvage GO:0043101 10 7 0,000 0,01294481 0,04726131 ! nucleoside transport GO:0015858 8 7 0,000 0,01294481 0,0471897 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01294481 0,04711831 ! parturition GO:0007567 14 7 0,000 0,01294481 0,04704713 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01294481 0,04697617 ! rRNA modification GO:0000154 14 7 0,000 0,01294481 0,04690543 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01294481 0,04683489 ! spindle checkpoint GO:0031577 15 7 0,000 0,01294481 0,04676457 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01294481 0,04669446 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01294481 0,04662455 ! macrophage differentiation GO:0030225 11 7 0,000 0,01294481 0,04655486 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01294481 0,04648538 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01294481 0,0464161 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01294481 0,04634703 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01294481 0,04627816 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01294481 0,0462095 ! fibrinolysis GO:0042730 10 7 0,000 0,01294481 0,04614104 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01294481 0,04607278 ! eating behavior GO:0042755 7 7 0,000 0,01294481 0,04600473 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01294481 0,04593688 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01294481 0,04586922 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01294481 0,04580177 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01294481 0,04573451 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01294481 0,04566745 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01294481 0,04560059 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01294481 0,04553392 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01294481 0,04546745 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01294481 0,04540117 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01294481 0,04533508 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01294481 0,04526919 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01294481 0,04520349 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01294481 0,04513797 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01294481 0,04507265 ! regulation of meiosis GO:0040020 12 7 0,000 0,01294481 0,04500752 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01294481 0,04494257 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01294481 0,04487781 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01294481 0,04481324 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01294481 0,04474885 ! transcription termination GO:0006353 13 7 0,000 0,01294481 0,04468465 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01294481 0,04462063 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01294481 0,0445568 ! anaphase GO:0051322 17 7 0,000 0,01294481 0,04449315 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01294481 0,04442968 ! axonal fasciculation GO:0007413 18 7 0,000 0,01294481 0,04436639 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01294481 0,04430328 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01294481 0,04424034 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01294481 0,04417759 ! diuresis GO:0030146 12 7 0,000 0,01294481 0,04411502 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01294481 0,04405262 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01294481 0,0439904 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01294481 0,04392835 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01294481 0,04386648 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01294481 0,04380479 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01294481 0,04374326 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01294481 0,04368191 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01294481 0,04362073 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01294481 0,04355972 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01294481 0,04349889 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01294481 0,04343822 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01294481 0,04337772 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01294481 0,04331739 ! lymph node development GO:0048535 10 7 0,000 0,01294481 0,04325723 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01294481 0,04319723 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01294481 0,0431374 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01294481 0,04307773 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01294481 0,04301824 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01294481 0,0429589 ! adult feeding behavior GO:0008343 9 7 0,000 0,01294481 0,04289973 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01294481 0,04284072 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01294481 0,04278187 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01294481 0,04272319 ! muscle adaptation GO:0043500 14 7 0,000 0,01294481 0,04266466 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01294481 0,0426063 ! retina homeostasis GO:0001895 12 7 0,000 0,01294481 0,04254809 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01294481 0,04249004 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01294481 0,04243216 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01294481 0,04237443 ! protein prenylation GO:0018342 18 7 0,000 0,01294481 0,04231685 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01294481 0,04225943 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01294481 0,04220217 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01294481 0,04214506 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,01303704 0,04238801 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,01303704 0,04233081 ! leukocyte differentiation GO:0002521 202 96 1,000 0,01384723 0,04490087 ! detection of stimulus GO:0051606 151 96 1,000 0,01384723 0,04484043 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01478058 0,04779848 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01478058 0,04773432 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01478058 0,04767033 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01478058 0,04760652 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01478058 0,04754287 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01478058 0,0474794 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01478058 0,04741609 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01478058 0,04735296 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01478058 0,04728999 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01478058 0,04722718 ! meiotic prophase I GO:0007128 13 8 0,000 0,01478058 0,04716455 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01478058 0,04710208 ! oligopeptide transport GO:0006857 15 8 0,000 0,01478058 0,04703977 ! UTP metabolic process GO:0046051 8 8 0,000 0,01478058 0,04697763 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01478058 0,04691566 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01478058 0,04685385 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01478058 0,0467922 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01478058 0,04673071 ! succinate metabolic process GO:0006105 14 8 0,000 0,01478058 0,04666938 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01478058 0,04660822 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01478058 0,04654721 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01478058 0,04648637 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01478058 0,04642568 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01478058 0,04636515 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01478058 0,04630478 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01478058 0,04624456 ! reflex GO:0060004 16 8 0,000 0,01478058 0,04618451 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01478058 0,0461246 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01478058 0,04606486 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01478058 0,04600526 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01478058 0,04594583 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01478058 0,04588654 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01478058 0,04582741 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01478058 0,04576843 ! pigment granule organization GO:0048753 16 8 0,000 0,01478058 0,0457096 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01478058 0,04565092 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01478058 0,0455924 ! histidine metabolic process GO:0006547 16 8 0,000 0,01478058 0,04553402 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01478058 0,04547579 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01478058 0,04541771 ! glycine catabolic process GO:0006546 13 8 0,000 0,01478058 0,04535978 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01478058 0,045302 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01478058 0,04524436 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01478058 0,04518687 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01478058 0,04512953 ! melanin metabolic process GO:0006582 15 8 0,000 0,01478058 0,04507233 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01478058 0,04501528 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01478058 0,04495837 ! macrophage activation GO:0042116 12 8 0,000 0,01478058 0,0449016 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01478058 0,04484498 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01478058 0,0447885 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01478058 0,04473216 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01478058 0,04467597 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01478058 0,04461991 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01478058 0,044564 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01478058 0,04450822 ! osteoblast development GO:0002076 16 8 0,000 0,01478058 0,04445259 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01478058 0,04439709 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01478058 0,04434173 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01478058 0,04428651 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01478058 0,04423143 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01478058 0,04417648 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01478058 0,04412167 ! response to UV-B GO:0010224 16 8 0,000 0,01478058 0,044067 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01478058 0,04401246 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01478058 0,04395806 ! intermediate filament organization GO:0045109 12 8 0,000 0,01478058 0,04390379 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01478058 0,04384965 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01478058 0,04379565 ! cellular extravasation GO:0045123 12 8 0,000 0,01478058 0,04374178 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01478058 0,04368805 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01478058 0,04363444 ! response to antibiotic GO:0046677 11 8 0,000 0,01478058 0,04358097 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01478058 0,04352762 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01478058 0,04347441 ! DNA topological change GO:0006265 12 8 0,000 0,01478058 0,04342133 ! response to tropane GO:0014073 15 8 0,000 0,01478058 0,04336838 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01478058 0,04331555 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01478058 0,04326286 ! melanosome transport GO:0032402 13 8 0,000 0,01478058 0,04321029 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,01478058 0,04315785 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01478058 0,04310554 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01478058 0,04305335 ! mast cell activation GO:0045576 14 8 0,000 0,01478058 0,04300129 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01478058 0,04294936 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01478058 0,04289755 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01478058 0,04284587 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01478058 0,04279431 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01478058 0,04274287 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01478058 0,04269156 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01478058 0,04264037 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01478058 0,0425893 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01478058 0,04253836 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01478058 0,04248754 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01478058 0,04243684 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01478058 0,04238626 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01478058 0,0423358 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01478058 0,04228546 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01478058 0,04223524 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01478058 0,04218514 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01478058 0,04213515 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01478058 0,04208529 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01478058 0,04203554 ! hormone catabolic process GO:0042447 17 8 0,000 0,01478058 0,04198591 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01478058 0,0419364 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01478058 0,04188701 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01478058 0,04183773 ! ATP catabolic process GO:0006200 11 8 0,000 0,01478058 0,04178857 ! blastocyst growth GO:0001832 19 8 0,000 0,01478058 0,04173952 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01478058 0,04169059 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01478058 0,04164177 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01478058 0,04159306 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01478058 0,04154447 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01478058 0,041496 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01478058 0,04144763 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01478058 0,04139938 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01478058 0,04135124 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01478058 0,04130322 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01478058 0,0412553 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01478058 0,0412075 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01478058 0,0411598 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01478058 0,04111222 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01478058 0,04106475 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01478058 0,04101738 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01478058 0,04097013 ! cell cycle arrest GO:0007050 213 100 1,000 0,01496066 0,04142157 ! regulation of developmental growth GO:0048638 15 9 0,000 0,016613 0,04594353 ! axon extension GO:0048675 15 9 0,000 0,016613 0,04589078 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,016613 0,04583815 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,016613 0,04578565 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,016613 0,04573326 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,016613 0,04568099 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,016613 0,04562885 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,016613 0,04557682 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,016613 0,04552491 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,016613 0,04547312 ! phosphate transport GO:0006817 19 9 0,000 0,016613 0,04542144 ! reproductive behavior GO:0019098 19 9 0,000 0,016613 0,04536988 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,016613 0,04531844 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,016613 0,04526712 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,016613 0,04521591 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,016613 0,04516482 ! GTP metabolic process GO:0046039 9 9 0,000 0,016613 0,04511385 ! RNA methylation GO:0001510 15 9 0,000 0,016613 0,04506299 ! elastic fiber assembly GO:0048251 15 9 0,000 0,016613 0,04501224 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,016613 0,04496161 ! artery development GO:0060840 24 9 0,000 0,016613 0,04491109 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,016613 0,04486068 ! regulation of glycolysis GO:0006110 21 9 0,000 0,016613 0,04481039 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,016613 0,04476021 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,016613 0,04471014 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,016613 0,04466019 ! chemosensory behavior GO:0007635 20 9 0,000 0,016613 0,04461034 ! microtubule bundle formation GO:0001578 21 9 0,000 0,016613 0,04456061 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,016613 0,04451099 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,016613 0,04446148 ! leukocyte degranulation GO:0043299 16 9 0,000 0,016613 0,04441208 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,016613 0,04436278 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,016613 0,0443136 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,016613 0,04426453 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,016613 0,04421556 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,016613 0,04416671 ! protein targeting to ER GO:0045047 22 9 0,000 0,016613 0,04411796 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,016613 0,04406931 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,016613 0,04402078 ! T cell selection GO:0045058 23 9 0,000 0,016613 0,04397235 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,016613 0,04392403 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,016613 0,04387582 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,016613 0,04382771 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,016613 0,0437797 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,016613 0,0437318 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,016613 0,04368401 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,016613 0,04363632 ! mannose metabolic process GO:0006013 13 9 0,000 0,016613 0,04358873 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,016613 0,04354125 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,016613 0,04349387 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,016613 0,0434466 ! receptor clustering GO:0043113 18 9 0,000 0,016613 0,04339942 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,016613 0,04335235 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,016613 0,04330538 ! ruffle organization GO:0031529 15 9 0,000 0,016613 0,04325852 ! retinol metabolic process GO:0042572 18 9 0,000 0,016613 0,04321175 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,016613 0,04316508 ! behavioral fear response GO:0001662 22 9 0,000 0,016613 0,04311852 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,016613 0,04307206 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,016613 0,04302569 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,016613 0,04297943 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,016613 0,04293326 ! oligodendrocyte development GO:0014003 10 9 0,000 0,016613 0,0428872 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,016613 0,04284123 ! segment specification GO:0007379 13 9 0,000 0,016613 0,04279536 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,016613 0,04274959 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,016613 0,04270392 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,016613 0,04265834 ! response to amine stimulus GO:0014075 13 9 0,000 0,016613 0,04261287 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,016613 0,04256748 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,016613 0,0425222 ! erythrocyte development GO:0048821 15 9 0,000 0,016613 0,04247701 ! gas homeostasis GO:0033483 16 9 0,000 0,016613 0,04243192 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,016613 0,04238692 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,016613 0,04234202 ! renal water homeostasis GO:0003091 14 9 0,000 0,016613 0,04229722 ! postreplication repair GO:0006301 22 9 0,000 0,016613 0,0422525 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,016613 0,04220789 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,016613 0,04216336 ! icosanoid secretion GO:0032309 15 9 0,000 0,016613 0,04211893 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,016613 0,0420746 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,016613 0,04203036 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,016613 0,04198621 ! regulation of cell division GO:0051302 15 9 0,000 0,016613 0,04194215 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,016613 0,04189818 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,016613 0,04185431 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,016613 0,04181053 ! sterol catabolic process GO:0016127 11 9 0,000 0,016613 0,04176684 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,016613 0,04172324 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,016613 0,04167974 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,016613 0,04163632 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,016613 0,041593 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,016613 0,04154976 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,016613 0,04150661 ! musculoskeletal movement GO:0050881 14 9 0,000 0,016613 0,04146356 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,016613 0,04142059 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,016613 0,04137771 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,016613 0,04133492 ! purine base metabolic process GO:0006144 21 9 0,000 0,016613 0,04129222 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,016613 0,04124961 ! pigment granule transport GO:0051904 17 9 0,000 0,016613 0,04120708 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,016613 0,04116464 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,016613 0,04112229 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,016613 0,04108003 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,016613 0,04103785 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,016613 0,04099576 ! mitochondrion localization GO:0051646 15 9 0,000 0,016613 0,04095376 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01844207 0,04541619 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01844207 0,04536975 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01844207 0,0453234 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01844207 0,04527716 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01844207 0,045231 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01844207 0,04518494 ! synapsis GO:0007129 13 10 0,000 0,01844207 0,04513898 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01844207 0,0450931 ! N-glycan processing GO:0006491 20 10 0,000 0,01844207 0,04504732 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01844207 0,04500164 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01844207 0,04495604 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01844207 0,04491054 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01844207 0,04486513 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01844207 0,04481981 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01844207 0,04477458 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01844207 0,04472945 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01844207 0,0446844 ! androgen metabolic process GO:0008209 17 10 0,000 0,01844207 0,04463945 ! phospholipid efflux GO:0033700 16 10 0,000 0,01844207 0,04459459 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01844207 0,04454981 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01844207 0,04450513 ! pathogenesis GO:0009405 13 10 0,000 0,01844207 0,04446053 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01844207 0,04441603 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01844207 0,04437161 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01844207 0,04432729 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01844207 0,04428305 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01844207 0,0442389 ! endoderm development GO:0007492 16 10 0,000 0,01844207 0,04419483 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01844207 0,04415086 ! arginine catabolic process GO:0006527 13 10 0,000 0,01844207 0,04410697 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01844207 0,04406317 ! proline metabolic process GO:0006560 13 10 0,000 0,01844207 0,04401946 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01844207 0,04397583 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01844207 0,04393229 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01844207 0,04388884 ! V(D)J recombination GO:0033151 28 10 0,000 0,01844207 0,04384547 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01844207 0,04380218 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01844207 0,04375899 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01844207 0,04371588 ! B cell proliferation GO:0042100 18 10 0,000 0,01844207 0,04367285 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01844207 0,0436299 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01844207 0,04358705 ! multicellular organism growth GO:0035264 18 10 0,000 0,01844207 0,04354427 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01844207 0,04350158 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01844207 0,04345897 ! epithelial cell development GO:0002064 20 10 0,000 0,01844207 0,04341645 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01844207 0,04337401 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01844207 0,04333165 ! macroautophagy GO:0016236 17 10 0,000 0,01844207 0,04328938 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01844207 0,04324719 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01844207 0,04320508 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01844207 0,04316305 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01844207 0,0431211 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01844207 0,04307924 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01844207 0,04303745 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01844207 0,04299575 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01844207 0,04295413 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01844207 0,04291259 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01844207 0,04287112 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01844207 0,04282974 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01844207 0,04278844 ! response to dsRNA GO:0043331 20 10 0,000 0,01844207 0,04274722 ! DNA ligation GO:0006266 19 10 0,000 0,01844207 0,04270608 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01844207 0,04266501 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01844207 0,04262403 ! melanosome localization GO:0032400 16 10 0,000 0,01844207 0,04258312 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01844207 0,04254229 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01844207 0,04250155 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01844207 0,04246087 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01844207 0,04242028 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01844207 0,04237976 ! mRNA cleavage GO:0006379 17 10 0,000 0,01844207 0,04233933 ! protein sumoylation GO:0016925 15 10 0,000 0,01844207 0,04229896 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01844207 0,04225868 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01844207 0,04221847 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01844207 0,04217834 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01844207 0,04213828 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01844207 0,0420983 ! salivary gland development GO:0007431 27 10 0,000 0,01844207 0,0420584 ! prophase GO:0051324 15 10 0,000 0,01844207 0,04201857 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01844207 0,04197882 ! apical protein localization GO:0045176 15 10 0,000 0,01844207 0,04193914 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01844207 0,04189954 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01844207 0,04186001 ! midbrain development GO:0030901 13 10 0,000 0,01844207 0,04182056 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01844207 0,04178118 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01844207 0,04174188 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01844207 0,04170264 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01844207 0,04166349 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01844207 0,0416244 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01844207 0,04158539 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01844207 0,04154645 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01844207 0,04150759 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01844207 0,0414688 ! oocyte development GO:0048599 17 10 0,000 0,01844207 0,04143008 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01844207 0,04139143 ! blastocyst formation GO:0001825 17 10 0,000 0,01844207 0,04135285 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01844207 0,04131435 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01844207 0,04127592 ! activation of innate immune response GO:0002218 12 10 0,000 0,01844207 0,04123756 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01844207 0,04119927 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01844207 0,04116105 ! response to nicotine GO:0035094 20 10 0,000 0,01844207 0,0411229 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01844207 0,04108483 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01844207 0,04104682 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,0202678 0,04506869 ! respiratory burst GO:0045730 17 11 0,000 0,0202678 0,04502707 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0202678 0,04498553 ! neuron fate specification GO:0048665 17 11 0,000 0,0202678 0,04494407 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0202678 0,04490269 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0202678 0,04486138 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0202678 0,04482015 ! thyroid gland development GO:0030878 26 11 0,000 0,0202678 0,04477899 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0202678 0,04473791 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0202678 0,0446969 ! response to pain GO:0048265 24 11 0,000 0,0202678 0,04465597 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0202678 0,04461511 ! T cell proliferation GO:0042098 26 11 0,000 0,0202678 0,04457433 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,0202678 0,04453362 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,0202678 0,04449299 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,0202678 0,04445243 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0202678 0,04441195 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0202678 0,04437154 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0202678 0,0443312 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0202678 0,04429093 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0202678 0,04425074 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0202678 0,04421062 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0202678 0,04417058 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0202678 0,04413061 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0202678 0,0440907 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,0202678 0,04405088 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0202678 0,04401112 ! UV protection GO:0009650 19 11 0,000 0,0202678 0,04397143 ! adult heart development GO:0007512 14 11 0,000 0,0202678 0,04393182 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0202678 0,04389228 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0202678 0,0438528 ! temperature homeostasis GO:0001659 17 11 0,000 0,0202678 0,0438134 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0202678 0,04377407 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0202678 0,04373482 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,0202678 0,04369563 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0202678 0,04365651 ! regulation of organ growth GO:0046620 13 11 0,000 0,0202678 0,04361746 ! pigment granule localization GO:0051875 20 11 0,000 0,0202678 0,04357848 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0202678 0,04353957 ! vasoconstriction GO:0042310 18 11 0,000 0,0202678 0,04350073 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0202678 0,04346196 ! embryonic axis specification GO:0000578 18 11 0,000 0,0202678 0,04342326 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0202678 0,04338463 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0202678 0,04334606 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0202678 0,04330757 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0202678 0,04326914 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0202678 0,04323078 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0202678 0,04319249 ! zymogen activation GO:0031638 15 11 0,000 0,0202678 0,04315426 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0202678 0,04311611 ! neuroblast proliferation GO:0007405 24 11 0,000 0,0202678 0,04307802 ! nucleosome positioning GO:0016584 15 11 0,000 0,0202678 0,04304 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0202678 0,04300204 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0202678 0,04296416 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0202678 0,04292634 ! acid secretion GO:0046717 18 11 0,000 0,0202678 0,04288858 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0202678 0,0428509 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0202678 0,04281327 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0202678 0,04277572 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0202678 0,04273823 ! oocyte differentiation GO:0009994 18 11 0,000 0,0202678 0,0427008 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0202678 0,04266345 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,0202678 0,04262615 ! cholesterol efflux GO:0033344 19 11 0,000 0,0202678 0,04258892 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0202678 0,04255176 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0202678 0,04251466 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0202678 0,04247763 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,0202678 0,04244066 ! embryonic gut development GO:0048566 15 11 0,000 0,0202678 0,04240376 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0202678 0,04236691 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0202678 0,04233014 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0202678 0,04229343 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0202678 0,04225678 ! defense response to fungus GO:0050832 13 11 0,000 0,0202678 0,04222019 ! developmental induction GO:0031128 19 11 0,000 0,0202678 0,04218367 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,0202678 0,04214721 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0202678 0,04211081 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0202678 0,04207448 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0202678 0,04203821 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0202678 0,042002 ! regulation of embryonic development GO:0045995 27 11 0,000 0,0202678 0,04196585 ! nucleus localization GO:0051647 19 11 0,000 0,0202678 0,04192977 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0202678 0,04189374 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02209019 0,04562146 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02209019 0,04558233 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02209019 0,04554327 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02209019 0,04550428 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02209019 0,04546535 ! virus-host interaction GO:0019048 29 12 0,000 0,02209019 0,0454265 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02209019 0,0453877 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02209019 0,04534898 ! cartilage condensation GO:0001502 20 12 0,000 0,02209019 0,04531032 ! mating GO:0007618 17 12 0,000 0,02209019 0,04527172 ! protein complex disassembly GO:0043241 27 12 0,000 0,02209019 0,04523319 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02209019 0,04519473 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02209019 0,04515633 ! hippocampus development GO:0021766 26 12 0,000 0,02209019 0,045118 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,02209019 0,04507973 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02209019 0,04504153 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02209019 0,04500339 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02209019 0,04496531 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02209019 0,0449273 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02209019 0,04488936 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02209019 0,04485148 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02209019 0,04481366 ! drug transport GO:0015893 16 12 0,000 0,02209019 0,04477591 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02209019 0,04473822 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02209019 0,04470059 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02209019 0,04466303 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02209019 0,04462552 ! focal adhesion formation GO:0048041 35 12 0,000 0,02209019 0,04458809 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02209019 0,04455071 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02209019 0,0445134 ! forebrain cell migration GO:0021885 21 12 0,000 0,02209019 0,04447615 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02209019 0,04443896 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02209019 0,04440184 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02209019 0,04436477 ! entry into host cell GO:0030260 32 12 0,000 0,02209019 0,04432777 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02209019 0,04429083 ! monoamine transport GO:0015844 18 12 0,000 0,02209019 0,04425395 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02209019 0,04421714 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02209019 0,04418038 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02209019 0,04414369 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02209019 0,04410705 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02209019 0,04407048 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02209019 0,04403397 ! protein homotetramerization GO:0051289 21 12 0,000 0,02209019 0,04399752 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02209019 0,04396112 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02209019 0,04392479 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02209019 0,04388852 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02209019 0,04385231 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02209019 0,04381616 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02209019 0,04378007 ! cranial nerve development GO:0021545 20 12 0,000 0,02209019 0,04374403 ! fucose catabolic process GO:0019317 22 12 0,000 0,02209019 0,04370806 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02209019 0,04367214 ! histone acetylation GO:0016573 26 12 0,000 0,02209019 0,04363629 ! histone methylation GO:0016571 26 12 0,000 0,02209019 0,04360049 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02209019 0,04356475 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02209019 0,04352907 ! gland morphogenesis GO:0022612 29 12 0,000 0,02209019 0,04349345 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02209019 0,04345789 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02209019 0,04342239 ! T cell homeostasis GO:0043029 25 12 0,000 0,02209019 0,04338694 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02209019 0,04335155 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02209019 0,04331622 ! spleen development GO:0048536 22 12 0,000 0,02209019 0,04328094 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02209019 0,04324573 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02209019 0,04321057 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02209019 0,04317547 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02209019 0,04314042 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02209019 0,04310543 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02209019 0,0430705 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02209019 0,04303563 ! response to cold GO:0009409 17 12 0,000 0,02209019 0,04300081 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02209019 0,04296605 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02209019 0,04293134 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02390926 0,04642911 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02390926 0,04639167 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02390926 0,04635429 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02390926 0,04631696 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02390926 0,0462797 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02390926 0,0462425 ! lipid localization GO:0010876 28 13 0,000 0,02390926 0,04620536 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02390926 0,04616827 ! organelle fusion GO:0048284 32 13 0,000 0,02390926 0,04613125 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02390926 0,04609429 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02390926 0,04605738 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02390926 0,04602054 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02390926 0,04598375 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02390926 0,04594702 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02390926 0,04591035 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02390926 0,04587374 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02390926 0,04583719 ! methionine metabolic process GO:0006555 27 13 0,000 0,02390926 0,04580069 ! plasma membrane organization GO:0007009 24 13 0,000 0,02390926 0,04576426 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02390926 0,04572788 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02390926 0,04569156 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02390926 0,04565529 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02390926 0,04561909 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02390926 0,04558294 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02390926 0,04554685 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02390926 0,04551081 ! exocrine system development GO:0035272 32 13 0,000 0,02390926 0,04547484 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02390926 0,04543892 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02390926 0,04540305 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02390926 0,04536725 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02390926 0,0453315 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02390926 0,0452958 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02390926 0,04526017 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02390926 0,04522458 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02390926 0,04518906 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02390926 0,04515359 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02390926 0,04511817 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02390926 0,04508281 ! ribosome assembly GO:0042255 17 13 0,000 0,02390926 0,04504751 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02390926 0,04501226 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02390926 0,04497707 ! chromatin silencing GO:0006342 26 13 0,000 0,02390926 0,04494193 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02390926 0,04490685 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02390926 0,04487182 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02390926 0,04483684 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02390926 0,04480192 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02390926 0,04476706 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02390926 0,04473225 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02390926 0,04469749 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02390926 0,04466279 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02390926 0,04462814 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02390926 0,04459354 ! embryonic placenta development GO:0001892 23 13 0,000 0,02390926 0,044559 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02390926 0,04452451 ! insulin secretion GO:0030073 23 13 0,000 0,02390926 0,04449008 ! actin filament polymerization GO:0030041 24 13 0,000 0,02390926 0,0444557 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02390926 0,04442137 ! acrosome reaction GO:0007340 18 13 0,000 0,02390926 0,04438709 ! rRNA transcription GO:0009303 25 14 0,000 0,025725 0,04772116 ! lactation GO:0007595 26 14 0,000 0,025725 0,04768439 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,025725 0,04764769 ! reproductive cellular process GO:0048610 20 14 0,000 0,025725 0,04761103 ! tRNA modification GO:0006400 20 14 0,000 0,025725 0,04757444 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,025725 0,0475379 ! regulation of S phase GO:0033261 23 14 0,000 0,025725 0,04750142 ! water transport GO:0006833 21 14 0,000 0,025725 0,04746499 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,025725 0,04742862 ! non-recombinational repair GO:0000726 25 14 0,000 0,025725 0,0473923 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,025725 0,04735604 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,025725 0,04731983 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,025725 0,04728369 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,025725 0,04724759 ! RNA polyadenylation GO:0043631 30 14 0,000 0,025725 0,04721155 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,025725 0,04717557 ! palate development GO:0060021 31 14 0,000 0,025725 0,04713964 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,025725 0,04710376 ! regulated secretory pathway GO:0045055 23 14 0,000 0,025725 0,04706794 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,025725 0,04703218 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,025725 0,04699646 ! arginine metabolic process GO:0006525 17 14 0,000 0,025725 0,04696081 ! regulation of heart rate GO:0002027 24 14 0,000 0,025725 0,0469252 ! organic alcohol transport GO:0015850 29 14 0,000 0,025725 0,04688965 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,025725 0,04685416 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,025725 0,04681872 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,025725 0,04678333 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,025725 0,04674799 ! neutral amino acid transport GO:0015804 26 14 0,000 0,025725 0,04671271 ! L-amino acid transport GO:0015807 30 14 0,000 0,025725 0,04667748 ! bone mineralization GO:0030282 17 14 0,000 0,025725 0,04664231 ! stem cell development GO:0048864 43 14 0,000 0,025725 0,04660719 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,025725 0,04657212 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,025725 0,0465371 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,025725 0,04650214 ! cerebellum development GO:0021549 21 14 0,000 0,025725 0,04646723 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,025725 0,04643237 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,025725 0,04639756 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,025725 0,0463628 ! cofactor transport GO:0051181 26 14 0,000 0,025725 0,0463281 ! NADP metabolic process GO:0006739 24 14 0,000 0,025725 0,04629345 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,025725 0,04625885 ! intestinal absorption GO:0050892 25 14 0,000 0,025725 0,0462243 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,025725 0,04618981 ! oxygen transport GO:0015671 21 14 0,000 0,025725 0,04615536 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,025725 0,04612097 ! male genitalia development GO:0030539 24 14 0,000 0,025725 0,04608663 ! regulation of axon extension GO:0030516 37 14 0,000 0,025725 0,04605234 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,025725 0,0460181 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02753742 0,04922365 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02753742 0,04918711 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02753742 0,04915062 ! superoxide anion generation GO:0042554 20 15 0,000 0,02753742 0,04911419 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02753742 0,0490778 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02753742 0,04904148 ! copper ion transport GO:0006825 20 15 0,000 0,02753742 0,0490052 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02753742 0,04896898 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02753742 0,04893282 ! sulfate transport GO:0008272 23 15 0,000 0,02753742 0,04889671 ! response to cAMP GO:0051591 22 15 0,000 0,02753742 0,04886065 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02753742 0,04882464 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02753742 0,04878869 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02753742 0,04875279 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02753742 0,04871694 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02753742 0,04868114 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02753742 0,0486454 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02753742 0,04860971 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02753742 0,04857407 ! pituitary gland development GO:0021983 29 15 0,000 0,02753742 0,04853849 ! vesicle coating GO:0006901 33 15 0,000 0,02753742 0,04850295 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02753742 0,04846747 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02753742 0,04843204 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02753742 0,04839667 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02753742 0,04836134 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02753742 0,04832607 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02753742 0,04829084 ! regulation of vasodilation GO:0042312 26 15 0,000 0,02753742 0,04825567 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02753742 0,04822055 ! histone deacetylation GO:0016575 20 15 0,000 0,02753742 0,04818548 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02753742 0,04815046 ! tissue regeneration GO:0042246 26 15 0,000 0,02753742 0,04811549 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02753742 0,04808058 ! water homeostasis GO:0030104 27 15 0,000 0,02753742 0,04804571 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02753742 0,0480109 ! muscle maintenance GO:0046716 26 15 0,000 0,02753742 0,04797613 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02753742 0,04794142 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02753742 0,04790675 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02753742 0,04787214 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02753742 0,04783757 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02753742 0,04780306 ! cell killing GO:0001906 29 15 0,000 0,02753742 0,04776859 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02753742 0,04773418 ! detection of bacterium GO:0016045 18 15 0,000 0,02753742 0,04769981 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,02753742 0,04766549 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02753742 0,04763123 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02753742 0,04759701 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02753742 0,04756284 ! peptide hormone processing GO:0016486 23 15 0,000 0,02753742 0,04752872 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02934653 0,05061488 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02934653 0,05057863 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02934653 0,05054242 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02934653 0,05050627 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02934653 0,05047016 ! bone remodeling GO:0046849 27 16 0,000 0,02934653 0,05043411 ! filopodium assembly GO:0046847 32 16 0,000 0,02934653 0,05039812 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02934653 0,05036217 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02934653 0,05032627 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02934653 0,05029043 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02934653 0,05025463 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02934653 0,05021889 ! startle response GO:0001964 28 16 0,000 0,02934653 0,0501832 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02934653 0,05014756 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02934653 0,05011197 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02934653 0,05007643 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02934653 0,05004094 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02934653 0,0500055 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02934653 0,04997011 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02934653 0,04993477 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02934653 0,04989948 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02934653 0,04986424 ! response to osmotic stress GO:0006970 25 16 0,000 0,02934653 0,04982905 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02934653 0,04979391 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02934653 0,04975882 ! fructose metabolic process GO:0006000 25 16 0,000 0,02934653 0,04972378 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02934653 0,04968878 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02934653 0,04965384 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02934653 0,04961895 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02934653 0,0495841 ! axon cargo transport GO:0008088 43 16 0,000 0,02934653 0,04954931 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02934653 0,04951456 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02934653 0,04947986 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,02934653 0,04944521 ! DNA replication initiation GO:0006270 27 16 0,000 0,02934653 0,04941061 ! neuron recognition GO:0008038 35 16 0,000 0,02934653 0,04937606 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02934653 0,04934155 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02934653 0,0493071 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02934653 0,04927269 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02934653 0,04923833 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02934653 0,04920401 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02934653 0,04916975 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02934653 0,04913553 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02934653 0,04910136 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02934653 0,04906724 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02934653 0,04903317 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02934653 0,04899914 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,02934653 0,04896516 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03115234 0,05194216 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,03115234 0,05190619 ! metencephalon development GO:0022037 30 17 0,000 0,03115234 0,05187026 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03115234 0,05183439 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03115234 0,05179857 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03115234 0,0517628 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03115234 0,05172708 ! signal complex assembly GO:0007172 41 17 0,000 0,03115234 0,0516914 ! endothelial cell migration GO:0043542 28 17 0,000 0,03115234 0,05165578 ! inositol metabolic process GO:0006020 28 17 0,000 0,03115234 0,0516202 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03115234 0,05158467 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03115234 0,0515492 ! glial cell development GO:0021782 27 17 0,000 0,03115234 0,05151377 ! limbic system development GO:0021761 36 17 0,000 0,03115234 0,05147839 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03115234 0,05144306 ! adult walking behavior GO:0007628 33 17 0,000 0,03115234 0,05140777 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03115234 0,05137254 ! heart looping GO:0001947 30 17 0,000 0,03115234 0,05133735 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03115234 0,05130221 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03115234 0,05126712 ! myoblast differentiation GO:0045445 45 17 0,000 0,03115234 0,05123208 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03115234 0,05119708 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03115234 0,05116214 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03115234 0,05112724 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03115234 0,05109239 ! glycine metabolic process GO:0006544 28 17 0,000 0,03115234 0,05105758 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03115234 0,05102283 ! NAD metabolic process GO:0019674 29 17 0,000 0,03115234 0,05098812 ! membrane budding GO:0006900 37 17 0,000 0,03115234 0,05095345 ! DNA integration GO:0015074 29 17 0,000 0,03115234 0,05091884 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03115234 0,05088427 ! regulation of protein binding GO:0043393 33 17 0,000 0,03115234 0,05084975 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03115234 0,05081528 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03115234 0,05078085 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03115234 0,05074647 ! genitalia development GO:0048806 30 17 0,000 0,03115234 0,05071213 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03115234 0,05067784 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03115234 0,0506436 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03115234 0,05060941 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03115234 0,05057526 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03115234 0,05054115 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03115234 0,0505071 ! steroid catabolic process GO:0006706 31 17 0,000 0,03115234 0,05047309 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03115234 0,05043912 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03115234 0,0504052 ! gas transport GO:0015669 25 17 0,000 0,03115234 0,05037133 ! organic cation transport GO:0015695 31 17 0,000 0,03115234 0,0503375 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03115234 0,05030371 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03115234 0,05026997 ! microspike assembly GO:0030035 36 17 0,000 0,03115234 0,05023628 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03115234 0,05020263 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03115234 0,05016903 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03295485 0,05303636 ! neuron maturation GO:0042551 42 18 0,000 0,03295485 0,05300091 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03295485 0,05296551 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03295485 0,05293015 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,03295485 0,05289484 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03295485 0,05285958 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03295485 0,05282436 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03295485 0,05278919 ! memory GO:0007613 31 18 0,000 0,03295485 0,05275407 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03295485 0,05271899 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03295485 0,05268396 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03295485 0,05264898 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03295485 0,05261404 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03295485 0,05257915 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03295485 0,05254431 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03295485 0,05250951 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03295485 0,05247476 ! response to retinoic acid GO:0032526 26 18 0,000 0,03295485 0,05244006 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03295485 0,0524054 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03295485 0,05237078 ! response to fungus GO:0009620 21 18 0,000 0,03295485 0,05233621 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03295485 0,05230169 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03295485 0,05226721 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03295485 0,05223278 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03295485 0,0521984 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03295485 0,05216406 ! vitamin transport GO:0051180 27 18 0,000 0,03295485 0,05212976 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03295485 0,05209551 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03295485 0,0520613 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03295485 0,05202714 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03295485 0,05199303 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,03295485 0,05195895 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03295485 0,05192493 ! nerve development GO:0021675 28 18 0,000 0,03295485 0,05189095 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03295485 0,05185701 ! protein secretion GO:0009306 39 19 0,000 0,03475406 0,05465247 ! positive regulation of translation GO:0045727 30 19 0,000 0,03475406 0,05461677 ! negative regulation of defense response GO:0031348 25 19 0,000 0,03475406 0,05458112 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,03475406 0,05454551 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,03475406 0,05450996 ! skin development GO:0043588 36 19 0,000 0,03475406 0,05447444 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,03475406 0,05443898 ! lipid phosphorylation GO:0046834 35 19 0,000 0,03475406 0,05440356 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03475406 0,05436819 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,03475406 0,05433286 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,03475406 0,05429758 ! bile acid metabolic process GO:0008206 29 19 0,000 0,03475406 0,05426234 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,03475406 0,05422715 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,03475406 0,05419201 ! cerebral cortex development GO:0021987 36 19 0,000 0,03475406 0,05415691 ! pigmentation during development GO:0048066 41 19 0,000 0,03475406 0,05412186 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,03475406 0,05408685 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,03475406 0,05405189 ! heme metabolic process GO:0042168 36 19 0,000 0,03475406 0,05401697 ! actin filament bundle formation GO:0051017 42 19 0,000 0,03475406 0,0539821 ! neuromuscular junction development GO:0007528 34 19 0,000 0,03475406 0,05394727 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,03475406 0,05391249 ! plasma membrane fusion GO:0045026 28 19 0,000 0,03475406 0,05387775 ! peptide cross-linking GO:0018149 37 19 0,000 0,03475406 0,05384306 ! protein export from nucleus GO:0006611 36 19 0,000 0,03475406 0,05380841 ! heart process GO:0003015 30 19 0,000 0,03475406 0,05377381 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,03475406 0,05373925 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,03475406 0,05370474 ! visual learning GO:0008542 36 19 0,000 0,03475406 0,05367026 ! cellular pigmentation GO:0033059 36 19 0,000 0,03475406 0,05363584 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,03475406 0,05360146 ! cell-cell junction organization GO:0045216 35 19 0,000 0,03475406 0,05356712 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,03475406 0,05353282 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,03475406 0,05349857 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,03475406 0,05346437 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,03475406 0,05343021 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,03475406 0,05339609 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,03475406 0,05336201 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,03475406 0,05332798 ! cilium assembly GO:0042384 37 19 0,000 0,03475406 0,05329399 ! peptide hormone secretion GO:0030072 31 19 0,000 0,03475406 0,05326005 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03654999 0,05597662 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03654999 0,05594101 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03654999 0,05590545 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03654999 0,05586993 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03654999 0,05583446 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03654999 0,05579903 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,03654999 0,05576365 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03654999 0,05572831 ! response to vitamin GO:0033273 31 20 0,000 0,03654999 0,05569301 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03654999 0,05565777 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,03654999 0,05562256 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03654999 0,0555874 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03654999 0,05555229 ! response to alkaloid GO:0043279 38 20 0,000 0,03654999 0,05551722 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03654999 0,05548219 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03654999 0,05544721 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03654999 0,05541227 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03654999 0,05537737 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03654999 0,05534252 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,03654999 0,05530772 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03654999 0,05527295 ! body fluid secretion GO:0007589 31 20 0,000 0,03654999 0,05523823 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03654999 0,05520356 ! peptide secretion GO:0002790 35 20 0,000 0,03654999 0,05516893 ! stem cell differentiation GO:0048863 53 20 0,000 0,03654999 0,05513434 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03654999 0,05509979 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,03654999 0,05506529 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03654999 0,05503083 ! sensory perception of pain GO:0019233 30 20 0,000 0,03654999 0,05499642 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03654999 0,05496204 ! diencephalon development GO:0021536 34 20 0,000 0,03654999 0,05492771 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03654999 0,05489343 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03654999 0,05485918 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03654999 0,05482498 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,03654999 0,05479082 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03654999 0,05475671 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03654999 0,05472263 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03654999 0,0546886 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,03654999 0,05465461 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03654999 0,05462066 ! regulation of glucose import GO:0046324 29 20 0,000 0,03654999 0,05458676 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03654999 0,0545529 ! actin filament-based movement GO:0030048 43 20 0,000 0,03654999 0,05451908 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03654999 0,0544853 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03654999 0,05445156 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03654999 0,05441787 ! negative regulation of translation GO:0017148 29 20 0,000 0,03654999 0,05438421 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03654999 0,0543506 ! regulation of cell killing GO:0031341 42 21 0,000 0,03834263 0,05698108 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03834263 0,05694591 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03834263 0,05691078 ! hormone secretion GO:0046879 38 21 0,000 0,03834263 0,05687569 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03834263 0,05684065 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03834263 0,05680565 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,03834263 0,05677069 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03834263 0,05673578 ! axis specification GO:0009798 38 21 0,000 0,03834263 0,0567009 ! ovarian follicle development GO:0001541 35 21 0,000 0,03834263 0,05666608 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,03834263 0,05663129 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03834263 0,05659655 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03834263 0,05656185 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03834263 0,05652719 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03834263 0,05649257 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03834263 0,056458 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03834263 0,05642347 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03834263 0,05638898 ! cytolysis GO:0019835 24 21 0,000 0,03834263 0,05635453 ! vasodilation GO:0042311 39 21 0,000 0,03834263 0,05632013 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03834263 0,05628577 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,03834263 0,05625145 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03834263 0,05621717 ! oogenesis GO:0048477 36 21 0,000 0,03834263 0,05618293 ! DNA modification GO:0006304 34 21 0,000 0,03834263 0,05614873 ! collagen fibril organization GO:0030199 59 21 0,000 0,03834263 0,05611458 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03834263 0,05608047 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,03834263 0,0560464 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03834263 0,05601237 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03834263 0,05597838 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03834263 0,05594443 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03834263 0,05591053 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,03834263 0,05587666 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03834263 0,05584284 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03834263 0,05580906 ! collagen catabolic process GO:0030574 28 21 0,000 0,03834263 0,05577531 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03834263 0,05574161 ! gut development GO:0048565 39 21 0,000 0,03834263 0,05570795 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,040132 0,05827253 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,040132 0,05823739 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,040132 0,05820228 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,040132 0,05816722 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,040132 0,0581322 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,040132 0,05809723 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,040132 0,05806229 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,040132 0,0580274 ! regeneration GO:0031099 41 22 0,000 0,040132 0,05799255 ! keratinization GO:0031424 28 22 0,000 0,040132 0,05795774 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,040132 0,05792297 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,040132 0,05788824 ! sensory perception of taste GO:0050909 28 22 0,000 0,040132 0,05785356 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,040132 0,05781892 ! vacuolar transport GO:0007034 36 22 0,000 0,040132 0,05778431 ! lysosome organization GO:0007040 41 22 0,000 0,040132 0,05774975 ! central nervous system neuron development GO:0021954 46 22 0,000 0,040132 0,05771524 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,040132 0,05768076 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,040132 0,05764632 ! fucose metabolic process GO:0006004 39 22 0,000 0,040132 0,05761193 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,040132 0,05757757 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,040132 0,05754326 ! ureteric bud development GO:0001657 43 22 0,000 0,040132 0,05750899 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,040132 0,05747476 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,040132 0,05744056 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,040132 0,05740641 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,040132 0,05737231 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,040132 0,05733824 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,040132 0,05730421 ! sarcomere organization GO:0045214 30 22 0,000 0,040132 0,05727022 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,040132 0,05723627 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,040132 0,05720236 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,040132 0,0571685 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,040132 0,05713467 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,040132 0,05710088 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,040132 0,05706713 ! protein stabilization GO:0050821 39 22 0,000 0,040132 0,05703343 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,0419181 0,05953656 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,0419181 0,05950144 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,0419181 0,05946636 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,0419181 0,05943131 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,0419181 0,05939631 ! gluconeogenesis GO:0006094 33 23 0,000 0,0419181 0,05936135 ! viral genome replication GO:0019079 41 23 0,000 0,0419181 0,05932644 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0419181 0,05929156 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0419181 0,05925672 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,0419181 0,05922193 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0419181 0,05918717 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,0419181 0,05915246 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0419181 0,05911778 ! visual behavior GO:0007632 42 23 0,000 0,0419181 0,05908315 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,0419181 0,05904856 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,0419181 0,05901401 ! response to ethanol GO:0045471 46 23 0,000 0,0419181 0,0589795 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,0419181 0,05894503 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,0419181 0,0589106 ! peroxisome organization GO:0007031 37 23 0,000 0,0419181 0,05887621 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0419181 0,05884186 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,0419181 0,05880755 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,0419181 0,05877328 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0419181 0,05873905 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,0419181 0,05870485 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,0419181 0,0586707 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,0419181 0,05863659 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0419181 0,05860252 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0419181 0,05856849 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0419181 0,0585345 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0419181 0,05850055 ! fatty acid transport GO:0015908 44 23 0,000 0,0419181 0,05846663 ! platelet activation GO:0030168 37 23 0,000 0,0419181 0,05843276 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,0419181 0,05839892 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0419181 0,05836513 ! hormone transport GO:0009914 40 23 0,000 0,0419181 0,05833137 ! cell-cell recognition GO:0009988 25 23 0,000 0,0419181 0,05829765 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0419181 0,05826397 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0419181 0,05823034 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,0419181 0,05819673 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0419181 0,05816317 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,0419181 0,05812965 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,04370093 0,06056707 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,04370093 0,0605322 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,04370093 0,06049737 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,04370093 0,06046259 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,04370093 0,06042784 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,04370093 0,06039313 ! vesicle docking GO:0048278 47 24 0,000 0,04370093 0,06035846 ! spinal cord development GO:0021510 47 24 0,000 0,04370093 0,06032383 ! vacuole organization GO:0007033 43 24 0,000 0,04370093 0,06028924 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,04370093 0,06025469 ! digestive system process GO:0022600 39 24 0,000 0,04370093 0,06022018 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,04370093 0,06018571 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,04370093 0,06015128 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,04370093 0,06011689 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,04370093 0,06008254 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,04370093 0,06004822 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,04370093 0,06001395 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,04370093 0,05997971 ! membrane depolarization GO:0051899 39 24 0,000 0,04370093 0,05994552 ! pallium development GO:0021543 49 24 0,000 0,04370093 0,05991136 ! pentose metabolic process GO:0019321 35 24 0,000 0,04370093 0,05987724 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,04370093 0,05984316 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,04370093 0,05980912 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,04370093 0,05977512 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,04370093 0,05974116 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,04370093 0,05970723 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,04370093 0,05967335 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,04370093 0,0596395 ! regulation of amine transport GO:0051952 40 24 0,000 0,04370093 0,05960569 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,0454805 0,06199779 ! myelination GO:0042552 45 25 0,000 0,0454805 0,06196268 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,0454805 0,06192761 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,0454805 0,06189259 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,0454805 0,0618576 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,0454805 0,06182265 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,0454805 0,06178774 ! receptor metabolic process GO:0043112 46 25 0,000 0,0454805 0,06175288 ! chromosome condensation GO:0030261 45 25 0,000 0,0454805 0,06171805 ! osteoblast differentiation GO:0001649 60 25 0,000 0,0454805 0,06168326 ! neural crest cell development GO:0014032 54 25 0,000 0,0454805 0,0616485 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,0454805 0,06161379 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,0454805 0,06157912 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,0454805 0,06154449 ! interaction with host GO:0051701 62 25 0,000 0,0454805 0,06150989 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,0454805 0,06147533 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,0454805 0,06144082 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,0454805 0,06140634 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,0454805 0,0613719 ! immunoglobulin production GO:0002377 55 25 0,000 0,0454805 0,0613375 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,0454805 0,06130313 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,0454805 0,06126881 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,0454805 0,06123452 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,0454805 0,06120028 ! telomere organization GO:0032200 43 25 0,000 0,0454805 0,06116607 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,0454805 0,0611319 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,0454805 0,06109776 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,04725683 0,06344862 ! embryonic pattern specification GO:0009880 44 26 0,000 0,04725683 0,06341323 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,04725683 0,06337789 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,04725683 0,06334258 ! initiation of viral infection GO:0019059 57 26 0,000 0,04725683 0,06330731 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,04725683 0,06327208 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,04725683 0,06323689 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,04725683 0,06320174 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,04725683 0,06316663 ! molting cycle process GO:0022404 50 26 0,000 0,04725683 0,06313155 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,04725683 0,06309652 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,04725683 0,06306152 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,04725683 0,06302657 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,04725683 0,06299165 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,04725683 0,06295677 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,04725683 0,06292193 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,04725683 0,06288713 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,04725683 0,06285236 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,04725683 0,06281764 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,04725683 0,06278295 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,04725683 0,0627483 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,04725683 0,06271369 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,04725683 0,06267912 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,04725683 0,06264459 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,04725683 0,06261009 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,04725683 0,06257563 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,04725683 0,06254121 ! blastocyst development GO:0001824 49 26 0,000 0,04725683 0,06250683 ! leukocyte proliferation GO:0070661 52 26 0,000 0,04725683 0,06247249 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,04725683 0,06243818 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,04725683 0,06240391 ! neuron fate commitment GO:0048663 48 27 0,000 0,0490299 0,06470979 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,0490299 0,06467431 ! iron ion transport GO:0006826 59 27 0,000 0,0490299 0,06463887 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0490299 0,06460348 ! protein amino acid acylation GO:0043543 55 27 0,000 0,0490299 0,06456812 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0490299 0,06453279 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0490299 0,06449751 ! fat cell differentiation GO:0045444 50 27 0,000 0,0490299 0,06446227 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0490299 0,06442706 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0490299 0,06439189 ! autophagy GO:0006914 41 27 0,000 0,0490299 0,06435676 ! male gonad development GO:0008584 44 27 0,000 0,0490299 0,06432167 ! response to toxin GO:0009636 47 27 0,000 0,0490299 0,06428662 ! primary neural tube formation GO:0014020 51 27 0,000 0,0490299 0,0642516 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0490299 0,06421663 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0490299 0,06418169 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,0490299 0,06414679 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0490299 0,06411193 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0490299 0,0640771 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0490299 0,06404232 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0490299 0,06400757 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,0490299 0,06397286 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05079974 0,06624616 ! circadian rhythm GO:0007623 50 28 0,000 0,05079974 0,06621028 ! dendrite development GO:0016358 59 28 0,000 0,05079974 0,06617443 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,05079974 0,06613862 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05079974 0,06610285 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05079974 0,06606712 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05079974 0,06603143 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,05079974 0,06599577 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,05079974 0,06596016 ! synaptogenesis GO:0007416 42 28 0,000 0,05079974 0,06592458 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,05079974 0,06588904 ! lipid oxidation GO:0034440 43 28 0,000 0,05079974 0,06585354 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05079974 0,06581808 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,05079974 0,06578265 ! translational initiation GO:0006413 65 29 0,000 0,05256634 0,06803368 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,05256634 0,0679971 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,05256634 0,06796056 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,05256634 0,06792406 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,05256634 0,0678876 ! catechol metabolic process GO:0009712 54 29 0,000 0,05256634 0,06785118 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,05256634 0,0678148 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,05256634 0,06777846 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,05256634 0,06774216 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,05256634 0,06770589 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,05256634 0,06766967 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,05256634 0,06763348 ! cell fate determination GO:0001709 60 29 0,000 0,05256634 0,06759733 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,05256634 0,06756122 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,05256634 0,06752515 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,05256634 0,06748912 ! tissue homeostasis GO:0001894 48 29 0,000 0,05256634 0,06745312 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,05256634 0,06741717 ! phenol metabolic process GO:0018958 55 30 0,000 0,05432971 0,0696416 ! zinc ion transport GO:0006829 45 30 0,000 0,05432971 0,06960451 ! membrane docking GO:0022406 61 30 0,000 0,05432971 0,06956747 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,05432971 0,06953047 ! cell junction assembly GO:0034329 78 30 0,000 0,05432971 0,0694935 ! regulation of innate immune response GO:0045088 51 30 0,000 0,05432971 0,06945658 ! acute-phase response GO:0006953 49 30 0,000 0,05432971 0,06941969 ! myofibril assembly GO:0030239 47 30 0,000 0,05432971 0,06938284 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,05432971 0,06934604 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,05432971 0,06930927 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,05432971 0,06927254 ! phospholipid transport GO:0015914 51 30 0,000 0,05432971 0,06923585 ! ensheathment of neurons GO:0007272 57 30 0,000 0,05432971 0,06919919 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,05432971 0,06916258 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,05432971 0,06912601 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,05432971 0,06908947 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,05432971 0,06905297 ! eye morphogenesis GO:0048592 60 30 0,000 0,05432971 0,06901651 ! regulation of B cell activation GO:0050864 50 30 0,000 0,05432971 0,06898009 ! response to heat GO:0009408 50 30 0,000 0,05432971 0,06894371 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,05608985 0,07113979 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,05608985 0,07110231 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,05608985 0,07106487 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,05608985 0,07102747 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,05608985 0,0709901 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,05608985 0,07095278 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,05608985 0,0709155 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,05608985 0,07087825 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,05608985 0,07084104 ! ovulation cycle process GO:0022602 49 31 0,000 0,05608985 0,07080388 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,05608985 0,07076675 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,05608985 0,07072966 ! peptide transport GO:0015833 55 31 0,000 0,05608985 0,07069261 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,05608985 0,0706556 ! iron ion homeostasis GO:0055072 54 31 0,000 0,05608985 0,07061862 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,05608985 0,07058169 ! mesoderm formation GO:0001707 69 31 0,000 0,05608985 0,07054479 ! natural killer cell activation GO:0030101 45 31 0,000 0,05608985 0,07050794 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,05608985 0,07047112 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,05608985 0,07043434 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,05608985 0,07039759 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,05608985 0,07036089 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,05608985 0,07032423 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,05784678 0,07248925 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,05784678 0,07245152 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,05784678 0,07241382 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,05784678 0,07237616 ! cholesterol transport GO:0030301 56 32 0,000 0,05784678 0,07233854 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,05784678 0,07230097 ! spliceosome assembly GO:0000245 67 32 0,000 0,05784678 0,07226343 ! spindle organization GO:0007051 46 32 0,000 0,05784678 0,07222593 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,05784678 0,07218847 ! metanephros development GO:0001656 74 32 0,000 0,05784678 0,07215104 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,05784678 0,07211366 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,05784678 0,07207631 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,05784678 0,07203901 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,05784678 0,07200174 ! muscle cell development GO:0055001 49 32 0,000 0,05784678 0,07196451 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,05784678 0,07192732 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,05784678 0,07189017 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,05784678 0,07185305 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,05784678 0,07181598 ! ovulation cycle GO:0042698 51 32 0,000 0,05784678 0,07177894 ! peripheral nervous system development GO:0007422 64 32 0,000 0,05784678 0,07174194 ! BMP signaling pathway GO:0030509 64 32 0,000 0,05784678 0,07170498 ! hindbrain development GO:0030902 61 32 0,000 0,05784678 0,07166805 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,05784678 0,07163117 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,05784678 0,07159432 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,05784678 0,07155751 ! gene silencing GO:0016458 65 32 0,000 0,05784678 0,07152074 ! post-embryonic development GO:0009791 69 33 0,000 0,0596005 0,07365116 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0596005 0,07361335 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0596005 0,07357558 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0596005 0,07353785 ! formation of primary germ layer GO:0001704 72 33 0,000 0,0596005 0,07350016 ! cell fate specification GO:0001708 52 33 0,000 0,0596005 0,0734625 ! sterol transport GO:0015918 57 33 0,000 0,0596005 0,07342489 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,0596005 0,07338731 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0596005 0,07334977 ! adult locomotory behavior GO:0008344 59 33 0,000 0,0596005 0,07331227 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,0596005 0,07327481 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,0596005 0,07323739 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,06135101 0,07534994 ! glial cell differentiation GO:0010001 63 34 0,000 0,06135101 0,0753115 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,06135101 0,07527309 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,06135101 0,07523473 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,06135101 0,0751964 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,06135101 0,07515811 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,06135101 0,07511986 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,06135101 0,07508165 ! mismatch repair GO:0006298 46 34 0,000 0,06135101 0,07504348 ! spermatid development GO:0007286 63 34 0,000 0,06135101 0,07500535 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,06135101 0,07496726 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,06135101 0,0749292 ! placenta development GO:0001890 53 34 0,000 0,06135101 0,07489119 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,06135101 0,07485321 ! regulation of muscle development GO:0048634 70 35 0,000 0,06309832 0,07694605 ! negative regulation of secretion GO:0051048 63 35 0,000 0,06309832 0,07690707 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,06309832 0,07686813 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,06309832 0,07682923 ! odontogenesis GO:0042476 66 35 0,000 0,06309832 0,07679037 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,06309832 0,07675155 ! female gonad development GO:0008585 58 35 0,000 0,06309832 0,07671277 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,06309832 0,07667402 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,06309832 0,07663532 ! cytokine production GO:0001816 59 35 0,000 0,06309832 0,07659665 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,06309832 0,07655802 ! neural tube formation GO:0001841 67 35 0,000 0,06309832 0,07651944 ! vesicle localization GO:0051648 64 35 0,000 0,06309832 0,07648089 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,06484244 0,07855534 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,06484244 0,07851581 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,06484244 0,07847631 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,06484244 0,07843686 ! cell junction organization GO:0034330 86 36 0,000 0,06484244 0,07839744 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,06484244 0,07835806 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,06484244 0,07831873 ! positive regulation of cell development GO:0010720 80 36 0,000 0,06484244 0,07827943 ! regulation of proteolysis GO:0030162 72 36 0,000 0,06484244 0,07824017 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,06484244 0,07820096 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,06484244 0,07816178 ! aerobic respiration GO:0009060 55 36 0,000 0,06484244 0,07812264 ! embryonic organ development GO:0048568 57 36 0,000 0,06484244 0,07808354 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,06484244 0,07804447 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,06484244 0,07800545 ! RNA export from nucleus GO:0006405 56 37 0,000 0,06658336 0,08005976 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,06658336 0,08001977 ! meiosis I GO:0007127 65 37 0,000 0,06658336 0,07997982 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,06658336 0,07993991 ! sister chromatid segregation GO:0000819 58 37 0,000 0,06658336 0,07990004 ! actomyosin structure organization GO:0031032 62 37 0,000 0,06658336 0,07986021 ! organic anion transport GO:0015711 68 37 0,000 0,06658336 0,07982042 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,06658336 0,07978067 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,06658336 0,07974095 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,06658336 0,07970128 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,06658336 0,07966165 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,06658336 0,07962206 ! glycogen metabolic process GO:0005977 61 37 0,000 0,06658336 0,0795825 ! pigment metabolic process GO:0042440 80 37 0,000 0,06658336 0,07954299 ! spermatid differentiation GO:0048515 66 37 0,000 0,06658336 0,07950351 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,06658336 0,07946408 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,06832111 0,08149756 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,06832111 0,08145718 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,06832111 0,08141683 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,06832111 0,08137653 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,06832111 0,08133626 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,06832111 0,08129604 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,06832111 0,08125585 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,06832111 0,08121571 ! lipid homeostasis GO:0055088 67 38 0,000 0,06832111 0,0811756 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,06832111 0,08113553 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,06832111 0,0810955 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,06832111 0,08105552 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,06832111 0,08101557 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,06832111 0,08097566 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,06832111 0,08093579 ! glucan metabolic process GO:0044042 62 38 0,000 0,06832111 0,08089596 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,07005567 0,08290898 ! mammary gland development GO:0030879 86 39 0,000 0,07005567 0,08286822 ! learning GO:0007612 77 39 0,000 0,07005567 0,0828275 ! ear morphogenesis GO:0042471 60 39 0,000 0,07005567 0,08278681 ! organic ether metabolic process GO:0018904 55 39 0,000 0,07005567 0,08274617 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,07005567 0,08270557 ! segmentation GO:0035282 67 39 0,000 0,07005567 0,08266501 ! ion transmembrane transport GO:0034220 66 39 0,000 0,07005567 0,08262449 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,07005567 0,082584 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,07005567 0,08254356 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,07005567 0,08250316 ! RNA modification GO:0009451 57 39 0,000 0,07005567 0,0824628 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,07005567 0,08242247 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,07178707 0,08441823 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,07178707 0,08437699 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,07178707 0,08433579 ! feeding behavior GO:0007631 59 40 0,000 0,07178707 0,08429463 ! negative regulation of binding GO:0051100 72 40 0,000 0,07178707 0,08425351 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,07178707 0,08421243 ! mesenchymal cell development GO:0014031 87 40 0,000 0,07178707 0,08417139 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,07178707 0,08413039 ! maintenance of protein location GO:0045185 91 40 0,000 0,07178707 0,08408943 ! cytokinesis GO:0000910 72 40 0,000 0,07178707 0,08404851 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,0735153 0,08603006 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,0735153 0,08598824 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,0735153 0,08594646 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,0735153 0,08590471 ! gliogenesis GO:0042063 88 41 0,000 0,0735153 0,08586301 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,0735153 0,08582135 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,0735153 0,08577973 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,0735153 0,08573815 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,0735153 0,08569661 ! female gamete generation GO:0007292 61 41 0,000 0,0735153 0,08565511 ! polyol metabolic process GO:0019751 66 41 0,000 0,0735153 0,08561365 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,0735153 0,08557223 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,07524037 0,08753787 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,07524037 0,08749556 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,07524037 0,08745329 ! regulation of tube size GO:0035150 71 42 0,000 0,07524037 0,08741107 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,07524037 0,08736888 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,07524037 0,08732673 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,07524037 0,08728463 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,07524037 0,08724256 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,07524037 0,08720054 ! neuron migration GO:0001764 79 42 0,000 0,07524037 0,08715856 ! regulation of protein secretion GO:0050708 71 42 0,000 0,07524037 0,08711661 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,07524037 0,08707471 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,07696228 0,08902464 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,07696228 0,08898186 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,07696228 0,08893912 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,07696228 0,08889642 ! glucose transport GO:0015758 65 43 0,000 0,07696228 0,08885376 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,07696228 0,08881115 ! neural tube development GO:0021915 77 43 0,000 0,07696228 0,08876857 ! striated muscle contraction GO:0006941 77 43 0,000 0,07696228 0,08872604 ! phagocytosis GO:0006909 90 43 0,000 0,07696228 0,08868355 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,07696228 0,08864109 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,07868104 0,09057732 ! hexose transport GO:0008645 67 44 0,000 0,07868104 0,090534 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,07868104 0,09049072 ! male sex differentiation GO:0046661 76 44 0,000 0,07868104 0,09044749 ! biopolymer methylation GO:0043414 84 44 0,000 0,07868104 0,09040429 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,07868104 0,09036114 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,07868104 0,09031803 ! developmental growth GO:0048589 82 44 0,000 0,07868104 0,09027496 ! maintenance of location in cell GO:0051651 97 44 0,000 0,07868104 0,09023193 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,08039666 0,09215549 ! glycolysis GO:0006096 65 45 0,000 0,08039666 0,09211161 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,08039666 0,09206776 ! leukocyte migration GO:0050900 68 45 0,000 0,08039666 0,09202396 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,08039666 0,09198021 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,08039666 0,09193649 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,08039666 0,09189281 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,08039666 0,09184918 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,08039666 0,09180559 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,08039666 0,09176204 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,08210915 0,09367217 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,08210915 0,09362778 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,08210915 0,09358342 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,08210915 0,09353911 ! pigmentation GO:0043473 100 46 0,000 0,08210915 0,09349484 ! response to insulin stimulus GO:0032868 95 46 0,000 0,08210915 0,09345062 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,08210915 0,09340643 ! positive regulation of defense response GO:0031349 76 47 0,000 0,0838185 0,09530591 ! response to calcium ion GO:0051592 81 47 0,000 0,0838185 0,09526089 ! endosome transport GO:0016197 108 47 0,000 0,0838185 0,09521591 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,0838185 0,09517098 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,0838185 0,09512609 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,0838185 0,09508124 ! JNK cascade GO:0007254 91 47 0,000 0,0838185 0,09503643 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,0838185 0,09499166 ! methylation GO:0032259 90 47 0,000 0,0838185 0,09494694 ! protein homooligomerization GO:0051260 76 47 0,000 0,0838185 0,09490226 ! Notch signaling pathway GO:0007219 96 48 0,000 0,08552472 0,09678856 ! cellular component disassembly GO:0022411 86 48 0,000 0,08552472 0,09674306 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,08552472 0,09669759 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,08552472 0,09665217 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,08552472 0,0966068 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,08552472 0,09656146 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,08552472 0,09651617 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,08552472 0,09647092 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,08552472 0,09642572 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,08722782 0,09829983 ! regulation of action potential GO:0001508 95 49 0,000 0,08722782 0,09825381 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,08722782 0,09820784 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,08722782 0,0981619 ! regulation of ion transport GO:0043269 77 49 0,000 0,08722782 0,09811601 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,08722782 0,09807016 ! peptide metabolic process GO:0006518 76 49 0,000 0,08722782 0,09802436 ! response to temperature stimulus GO:0009266 76 49 0,000 0,08722782 0,09797859 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,08722782 0,09793287 ! endocrine system development GO:0035270 104 49 0,000 0,08722782 0,0978872 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,08722782 0,09784156 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,08722782 0,09779597 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,08722782 0,09775042 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,08892781 0,09960909 ! neuromuscular process GO:0050905 99 50 0,000 0,08892781 0,09956274 ! regulation of ossification GO:0030278 117 50 0,000 0,08892781 0,09951643 ! inner ear development GO:0048839 79 50 0,000 0,08892781 0,09947016 ! histone modification GO:0016570 91 50 0,000 0,08892781 0,09942394 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,08892781 0,09937776 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,08892781 0,09933162 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,08892781 0,09928553 ! positive regulation of binding GO:0051099 78 51 0,000 0,09062469 0,10113312 ! viral infectious cycle GO:0019058 99 51 0,000 0,09062469 0,10108623 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,09062469 0,10103939 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,09062469 0,10099259 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,09062469 0,10094584 ! excretion GO:0007588 83 51 0,000 0,09062469 0,10089912 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,09062469 0,10085245 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,09062469 0,10080583 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,09062469 0,10075925 ! vesicle organization GO:0016050 107 51 0,000 0,09062469 0,10071271 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,09062469 0,10066621 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,09062469 0,10061975 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,09231847 0,10245306 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,09231847 0,10240582 ! membrane fusion GO:0006944 110 52 0,000 0,09231847 0,10235863 ! positive regulation of growth GO:0045927 90 52 0,000 0,09231847 0,10231148 ! covalent chromatin modification GO:0016569 101 52 0,000 0,09231847 0,10226438 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,09231847 0,10221732 ! amino acid activation GO:0043038 92 52 0,000 0,09231847 0,1021703 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,09231847 0,10212332 ! synapse organization GO:0050808 85 52 0,000 0,09231847 0,10207639 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,09400914 0,10389802 ! RNA catabolic process GO:0006401 93 53 0,000 0,09400914 0,10385032 ! regulation of translational initiation GO:0006446 82 53 0,000 0,09400914 0,10380266 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,09400914 0,10375504 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,09400914 0,10370747 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,09400914 0,10365994 ! cell maturation GO:0048469 100 53 0,000 0,09400914 0,10361246 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,09400914 0,10356502 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,09569672 0,10537589 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,09569672 0,10532768 ! cell recognition GO:0008037 85 54 0,000 0,09569672 0,10527952 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,09569672 0,10523141 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,09569672 0,10518333 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,09569672 0,10513531 ! chloride transport GO:0006821 90 55 0,000 0,09738122 0,10693711 ! glucose catabolic process GO:0006007 82 55 0,000 0,09738122 0,10688833 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,09738122 0,10683959 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,09738122 0,10679089 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,09738122 0,10674224 ! gastrulation GO:0007369 112 55 0,000 0,09738122 0,10669363 ! heart morphogenesis GO:0003007 97 55 0,000 0,09738122 0,10664507 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,09738122 0,10659655 ! RNA elongation GO:0006354 79 55 0,000 0,09738122 0,10654807 ! nuclear export GO:0051168 97 55 0,000 0,09738122 0,10649964 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,09738122 0,10645126 ! regulation of actin filament length GO:0030832 105 56 0,000 0,09906263 0,1082401 ! sensory perception of smell GO:0007608 80 56 0,000 0,09906263 0,10819096 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,09906263 0,10814188 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,09906263 0,10809283 ! proton transport GO:0015992 94 56 0,000 0,09906263 0,10804383 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,09906263 0,10799488 ! muscle fiber development GO:0048747 112 57 0,000 0,10074097 0,10977481 ! lipid modification GO:0030258 97 57 0,000 0,10074097 0,10972511 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,10074097 0,10967546 ! maintenance of location GO:0051235 118 57 0,000 0,10074097 0,10962586 ! hydrogen transport GO:0006818 97 58 0,000 0,10241624 0,11139849 ! regulation of endocytosis GO:0030100 91 58 0,000 0,10241624 0,11134815 ! adult behavior GO:0030534 99 58 0,000 0,10241624 0,11129786 ! positive regulation of secretion GO:0051047 95 59 0,000 0,10408844 0,11306401 ! regulation of cellular component size GO:0032535 109 59 0,000 0,10408844 0,11301299 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,10408844 0,11296201 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,10408844 0,11291108 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,10408844 0,1128602 ! DNA catabolic process GO:0006308 86 59 0,000 0,10408844 0,11280936 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,10408844 0,11275857 ! establishment of organelle localization GO:0051656 109 59 0,000 0,10408844 0,11270782 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,10575758 0,11446367 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,10575758 0,1144122 ! regulation of heart contraction GO:0008016 110 60 0,000 0,10575758 0,11436078 ! camera-type eye development GO:0043010 116 60 0,000 0,10575758 0,1143094 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,10575758 0,11425808 ! kidney development GO:0001822 122 60 0,000 0,10575758 0,11420679 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,10742367 0,11595394 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,10742367 0,11590195 ! mesoderm development GO:0007498 119 61 0,000 0,10742367 0,11585 ! tRNA processing GO:0008033 89 61 0,000 0,10742367 0,11579809 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,10742367 0,11574623 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,10742367 0,11569442 ! ear development GO:0043583 103 62 0,000 0,1090867 0,11743293 ! viral reproductive process GO:0022415 126 62 0,000 0,1090867 0,11738042 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,1090867 0,11732794 ! gonad development GO:0008406 98 62 0,000 0,1090867 0,11727552 ! regulation of mitosis GO:0007088 105 63 0,000 0,1107467 0,11900695 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,1107467 0,11895382 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,1107467 0,11890074 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,1107467 0,11884771 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,11240366 0,12057209 ! cell redox homeostasis GO:0045454 102 64 0,000 0,11240366 0,12051836 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,11240366 0,12046467 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,11240366 0,12041104 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,11240366 0,12035745 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,11405758 0,12207408 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,11405758 0,1220198 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,11405758 0,12196557 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,11405758 0,12191139 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,11405758 0,12185725 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,11570848 0,12356618 ! actin filament organization GO:0007015 148 66 0,000 0,11570848 0,12351136 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,11570848 0,12345658 ! extracellular matrix organization GO:0030198 133 66 0,000 0,11570848 0,12340186 ! secondary metabolic process GO:0019748 116 66 0,000 0,11570848 0,12334719 ! developmental maturation GO:0021700 116 66 0,000 0,11570848 0,12329256 ! cell projection assembly GO:0030031 120 66 0,000 0,11570848 0,12323798 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,11735635 0,12493778 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,11735635 0,12488252 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,11735635 0,12482732 ! activation of MAPK activity GO:0000187 115 67 0,000 0,11735635 0,12477216 ! chromosome segregation GO:0007059 113 67 0,000 0,11735635 0,12471704 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,11735635 0,12466198 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,11735635 0,12460697 ! hexose catabolic process GO:0019320 104 67 0,000 0,11735635 0,124552 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,11735635 0,12449708 ! activation of immune response GO:0002253 105 67 0,000 0,11735635 0,12444222 ! amino acid transport GO:0006865 125 68 0,000 0,11900121 0,1261308 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,11900121 0,12607526 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,11900121 0,12601977 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,11900121 0,12596433 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,11900121 0,12590894 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,11900121 0,12585359 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,11900121 0,1257983 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,12064306 0,12747791 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,12064306 0,12742195 ! urogenital system development GO:0001655 137 69 0,000 0,12064306 0,12736604 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,12064306 0,12731018 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,12064306 0,12725437 ! antigen processing and presentation GO:0019882 104 69 0,000 0,12064306 0,1271986 ! appendage morphogenesis GO:0035107 135 70 0,000 0,12228191 0,12887003 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,12391775 0,13053683 ! reproductive structure development GO:0048608 113 71 0,000 0,12391775 0,1304797 ! appendage development GO:0048736 136 71 0,000 0,12391775 0,13042262 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,12391775 0,13036559 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,12391775 0,13030861 ! regulation of immune effector process GO:0002697 137 71 0,000 0,12391775 0,13025169 ! acute inflammatory response GO:0002526 113 72 0,000 0,1255506 0,13191037 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,1255506 0,13185279 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,1255506 0,13179527 ! carbohydrate transport GO:0008643 110 72 0,000 0,1255506 0,13173779 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,1255506 0,13168036 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,1255506 0,13162298 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,1255506 0,13156566 ! learning or memory GO:0007611 147 73 0,000 0,12718046 0,13321558 ! regulation of blood pressure GO:0008217 125 73 0,000 0,12718046 0,13315761 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,12718046 0,13309969 ! fertilization GO:0009566 90 73 0,000 0,12718046 0,13304182 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,12880734 0,13468512 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,12880734 0,13462661 ! neurotransmitter transport GO:0006836 123 74 0,000 0,12880734 0,13456815 ! exocytosis GO:0006887 133 74 0,000 0,12880734 0,13450975 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,12880734 0,13445139 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,12880734 0,13439309 ! eye development GO:0001654 143 74 0,000 0,12880734 0,13433483 ! organelle localization GO:0051640 136 74 0,000 0,12880734 0,13427663 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,13043124 0,13591059 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,13043124 0,13585176 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,13043124 0,13579297 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,13043124 0,13573424 ! rhythmic process GO:0048511 128 75 0,000 0,13043124 0,13567556 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,13205216 0,13730229 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,13205216 0,13724298 ! defense response to bacterium GO:0042742 89 76 0,000 0,13205216 0,13718372 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,13205216 0,13712452 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,13205216 0,13706536 ! regulation of catabolic process GO:0009894 161 76 0,000 0,13205216 0,13700626 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,13367012 0,13862514 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,13367012 0,13856541 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,13367012 0,13850573 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,13367012 0,13844611 ! blood coagulation GO:0007596 146 78 0,000 0,13528512 0,14005852 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,13528512 0,13999828 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,13528512 0,13993809 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,13528512 0,13987795 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,13689716 0,14148392 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,13689716 0,14142317 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,13689716 0,14136247 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,13689716 0,14130183 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,13850624 0,14290138 ! response to metal ion GO:0010038 140 80 0,000 0,13850624 0,14284013 ! muscle cell differentiation GO:0042692 159 80 0,000 0,13850624 0,14277893 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,13850624 0,14271778 ! inorganic anion transport GO:0015698 138 80 0,000 0,13850624 0,14265669 ! digestion GO:0007586 112 81 0,000 0,14011238 0,14424921 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,14011238 0,14418751 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,14011238 0,14412586 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,14011238 0,14406427 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,14171558 0,14565045 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,14171558 0,14558826 ! response to nutrient GO:0007584 125 82 0,000 0,14171558 0,14552612 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,14171558 0,14546403 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,14171558 0,145402 ! regulation of lyase activity GO:0051339 160 83 0,000 0,14331585 0,14698121 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,14491318 0,14855608 ! hemostasis GO:0007599 158 84 0,000 0,14491318 0,14849281 ! negative regulation of transport GO:0051051 153 84 0,000 0,14491318 0,14842959 ! regulation of ligase activity GO:0051340 142 84 0,000 0,14491318 0,14836643 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,14491318 0,14830332 ! response to unfolded protein GO:0006986 131 85 0,000 0,14650759 0,14987128 ! nucleosome assembly GO:0006334 122 85 0,000 0,14650759 0,14980759 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,14650759 0,14974395 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,14650759 0,14968037 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,14809908 0,1512421 ! response to inorganic substance GO:0010035 153 86 0,000 0,14809908 0,15117793 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,14809908 0,15111382 ! chromatin assembly GO:0031497 124 86 0,000 0,14809908 0,15104976 ! tube morphogenesis GO:0035239 176 86 0,000 0,14809908 0,15098575 ! alcohol catabolic process GO:0046164 130 86 0,000 0,14809908 0,1509218 ! amine transport GO:0015837 155 86 0,000 0,14809908 0,15085791 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,14968765 0,15241155 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,14968765 0,15234708 ! regulation of protein transport GO:0051223 154 87 0,000 0,14968765 0,15228266 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,15127332 0,15383077 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,15127332 0,15376578 ! regulation of DNA binding GO:0051101 155 88 0,000 0,15127332 0,15370084 ! gland development GO:0048732 206 88 0,000 0,15127332 0,15363596 ! regulation of neurological system process GO:0031644 148 88 0,000 0,15127332 0,15357114 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,15127332 0,15350637 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,15285608 0,1550471 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,15443594 0,15658359 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,15443594 0,15651763 ! sex differentiation GO:0007548 145 90 0,000 0,15443594 0,15645173 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,15443594 0,15638588 ! sterol metabolic process GO:0016125 152 91 0,000 0,1560129 0,1579163 ! response to protein stimulus GO:0051789 149 91 0,000 0,1560129 0,15784989 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,1560129 0,15778354 ! regulation of defense response GO:0031347 149 92 0,000 0,15758698 0,15930852 ! nucleosome organization GO:0034728 138 92 0,000 0,15758698 0,15924161 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,15758698 0,15917476 ! vitamin metabolic process GO:0006766 139 92 0,000 0,15758698 0,15910796 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,15915818 0,16062692 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,15915818 0,16055957 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,15915818 0,16049228 ! regulation of membrane potential GO:0042391 164 93 0,000 0,15915818 0,16042504 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,16072649 0,161938 ! female pregnancy GO:0007565 164 94 0,000 0,16072649 0,16187021 ! transcription initiation GO:0006352 153 94 0,000 0,16072649 0,16180249 ! regulation of T cell activation GO:0050863 158 94 0,000 0,16072649 0,16173481 ! forebrain development GO:0030900 188 95 0,000 0,16229194 0,16324181 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,16229194 0,16317359 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,16385451 0,16467584 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,16385451 0,16460708 ! positive regulation of immune response GO:0050778 156 96 0,000 0,16385451 0,16453838 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,16541423 0,16603531 ! protein ubiquitination GO:0016567 217 97 0,000 0,16541423 0,16596607 ! hormone metabolic process GO:0042445 157 97 0,000 0,16541423 0,16589689 ! regulation of protein localization GO:0032880 176 97 0,000 0,16541423 0,16582776 ! response to virus GO:0009615 160 98 0,000 0,16697108 0,16731879 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,16697108 0,16724913 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,16697108 0,16717953 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,16852508 0,16866529 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,16852508 0,16859516 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,16852508 0,16852508 GO:0060538|skeletal muscle organ development,