pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1007-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 3,000 8,143E-10 1,873E-06 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 3,000 3,374E-08 3,88E-05 ! regulation of vascular endothelial growth factor production GO:0010574 19 11 3,000 5,287E-08 4,053E-05 ! regulation of JAK-STAT cascade GO:0046425 61 42 4,000 4,297E-07 2,471E-04 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 3,000 6,074E-07 2,794E-04 ! positive regulation of muscle hypertrophy GO:0014742 9 6 2,000 9,286E-07 3,56E-04 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of epidermal cell differentiation GO:0045604 7 6 2,000 9,286E-07 3,051E-04 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 3,000 1,373E-06 3,946E-04 ! cytokine-mediated signaling pathway GO:0019221 76 54 4,000 1,545E-06 3,947E-04 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 2,000 1,621E-06 3,728E-04 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of epidermis development GO:0045684 11 7 2,000 1,621E-06 3,389E-04 ! UTP metabolic process GO:0046051 8 8 2,000 2,586E-06 4,957E-04 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! regulation of muscle hypertrophy GO:0014743 11 8 2,000 2,586E-06 4,576E-04 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of Notch signaling pathway GO:0008593 18 8 2,000 2,586E-06 4,249E-04 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 3,000 3,13E-06 4,8E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 4,000 3,347E-06 4,812E-04 ! regulation of muscle adaptation GO:0043502 12 9 2,000 3,87E-06 5,235E-04 ! CTP metabolic process GO:0046036 9 9 2,000 3,87E-06 4,944E-04 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 2,000 3,87E-06 4,684E-04 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 3,000 5,438E-06 6,254E-04 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 2,000 5,514E-06 6,039E-04 ! positive regulation of acute inflammatory response GO:0002675 14 10 2,000 5,514E-06 5,764E-04 ! positive regulation of phosphorylation GO:0042327 102 70 4,000 5,651E-06 5,651E-04 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 4,000 6,496E-06 6,226E-04 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of JAK-STAT cascade GO:0046427 45 34 3,000 6,975E-06 6,417E-04 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 3,000 9,851E-06 8,715E-04 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 2,000 1,006E-05 8,566E-04 ! regulation of epidermis development GO:0045682 17 12 2,000 1,006E-05 8,26E-04 ! regulation of epithelial cell proliferation GO:0050678 71 39 3,000 1,22E-05 9,677E-04 ! regulation of acute inflammatory response GO:0002673 19 13 2,000 1,304E-05 9,996E-04 ! positive regulation of response to external stimulus GO:0032103 65 40 3,000 1,352E-05 1,003E-03 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 2,000 1,655E-05 1,19E-03 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 2,000 2,063E-05 1,438E-03 ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 2,000 2,533E-05 1,713E-03 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 2,000 2,533E-05 1,664E-03 ! regulation of response to external stimulus GO:0032101 139 96 4,000 2,653E-05 1,695E-03 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 3,000 2,816E-05 1,751E-03 ! positive regulation of cytokine production GO:0001819 73 48 3,000 2,816E-05 1,704E-03 ! positive regulation of anti-apoptosis GO:0045768 29 18 2,000 3,672E-05 2,165E-03 ! regulation of bone remodeling GO:0046850 90 53 3,000 4,18E-05 2,404E-03 ! somatic diversification of immunoglobulins GO:0016445 29 19 2,000 4,349E-05 2,439E-03 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 2,000 4,349E-05 2,381E-03 ! regulation of tissue remodeling GO:0034103 91 54 3,000 4,502E-05 2,408E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 5,103E-05 2,667E-03 ! positive regulation of inflammatory response GO:0050729 30 20 2,000 5,103E-05 2,608E-03 ! positive regulation of osteoblast differentiation GO:0045669 33 20 2,000 5,103E-05 2,551E-03 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 2,000 5,937E-05 2,906E-03 GO:0016444|somatic cell DNA recombination, ! immunoglobulin production GO:0002377 33 21 2,000 5,937E-05 2,845E-03 GO:0002440|production of molecular mediator of immune response, ! positive regulation of adaptive immune response GO:0002821 31 21 2,000 5,937E-05 2,787E-03 ! response to cytokine stimulus GO:0034097 47 21 2,000 5,937E-05 2,731E-03 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 2,000 5,937E-05 2,678E-03 ! regulation of anti-apoptosis GO:0045767 36 22 2,000 6,857E-05 3,033E-03 ! vasculogenesis GO:0001570 33 22 2,000 6,857E-05 2,976E-03 ! somatic diversification of immune receptors GO:0002200 35 23 2,000 7,865E-05 3,35E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 3,000 8,801E-05 3,681E-03 ! regulation of endothelial cell proliferation GO:0001936 46 24 2,000 8,965E-05 3,682E-03 ! regulation of osteoblast differentiation GO:0045667 37 24 2,000 8,965E-05 3,617E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,31E-04 5,195E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 1,000 1,31E-04 5,107E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 1,000 1,31E-04 5,022E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 1,31E-04 4,939E-03 ! early endosome to late endosome transport GO:0045022 11 5 1,000 1,31E-04 4,86E-03 ! glial cell migration GO:0008347 10 5 1,000 1,31E-04 4,783E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 1,31E-04 4,708E-03 ! spindle assembly GO:0051225 5 5 1,000 1,31E-04 4,635E-03 ! organ regeneration GO:0031100 7 5 1,000 1,31E-04 4,565E-03 ! positive regulation of microtubule polymerization GO:0031116 9 5 1,000 1,31E-04 4,497E-03 ! response to hypoxia GO:0001666 132 72 3,000 1,394E-04 4,716E-03 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 2,000 1,436E-04 4,787E-03 ! response to oxygen levels GO:0070482 137 74 3,000 1,551E-04 5,095E-03 ! positive regulation of T cell proliferation GO:0042102 44 29 2,000 1,597E-04 5,175E-03 ! mismatch repair GO:0006298 34 29 2,000 1,597E-04 5,103E-03 ! regulation of DNA binding GO:0051101 119 77 3,000 1,809E-04 5,7E-03 ! positive regulation of protein modification process GO:0031401 107 78 3,000 1,902E-04 5,91E-03 ! prostate gland development GO:0030850 9 6 1,000 1,96E-04 6,012E-03 ! establishment of chromosome localization GO:0051303 9 6 1,000 1,96E-04 5,933E-03 GO:0050000|chromosome localization, ! axonal fasciculation GO:0007413 9 6 1,000 1,96E-04 5,856E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 1,96E-04 5,781E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 1,000 1,96E-04 5,707E-03 ! regulation of microtubule polymerization GO:0031113 11 6 1,000 1,96E-04 5,636E-03 ! male meiosis GO:0007140 7 6 1,000 1,96E-04 5,567E-03 ! meiotic prophase I GO:0007128 9 6 1,000 1,96E-04 5,499E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 1,96E-04 5,432E-03 ! mRNA stabilization GO:0048255 15 6 1,000 1,96E-04 5,368E-03 GO:0043489|RNA stabilization, ! negative regulation of DNA recombination GO:0045910 9 6 1,000 1,96E-04 5,305E-03 ! gas homeostasis GO:0033483 11 6 1,000 1,96E-04 5,243E-03 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 2,000 2,361E-04 6,24E-03 ! mRNA catabolic process GO:0006402 48 34 2,000 2,582E-04 6,749E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,738E-04 7,076E-03 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 1,000 2,738E-04 6,997E-03 ! T-helper 1 type immune response GO:0042088 11 7 1,000 2,738E-04 6,92E-03 ! vesicle fusion GO:0006906 15 7 1,000 2,738E-04 6,845E-03 ! glycogen metabolic process GO:0005977 48 35 2,000 2,817E-04 6,967E-03 ! positive regulation of leukocyte proliferation GO:0070665 50 35 2,000 2,817E-04 6,892E-03 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 3,000 2,895E-04 7,01E-03 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 3,000 3,025E-04 7,247E-03 ! tissue remodeling GO:0048771 62 36 2,000 3,065E-04 7,267E-03 ! glucan metabolic process GO:0044042 49 36 2,000 3,065E-04 7,193E-03 GO:0006073|cellular glucan metabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 3,000 3,159E-04 7,338E-03 ! ribonucleoside metabolic process GO:0009119 48 37 2,000 3,327E-04 7,651E-03 ! regulation of T cell proliferation GO:0042129 58 38 2,000 3,602E-04 8,204E-03 ! axon extension GO:0048675 11 8 1,000 3,642E-04 8,213E-03 ! induction of positive chemotaxis GO:0050930 14 8 1,000 3,642E-04 8,133E-03 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 1,000 3,642E-04 8,055E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 3,642E-04 7,978E-03 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 3,642E-04 7,903E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 3,642E-04 7,829E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 3,642E-04 7,756E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 3,642E-04 7,685E-03 ! prophase GO:0051324 11 8 1,000 3,642E-04 7,615E-03 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 3,642E-04 7,547E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 3,642E-04 7,479E-03 ! cell growth GO:0016049 61 39 2,000 3,893E-04 7,923E-03 ! regulation of binding GO:0051098 151 95 3,000 4,051E-04 8,174E-03 ! energy reserve metabolic process GO:0006112 59 41 2,000 4,517E-04 9,033E-03 ! positive regulation of DNA binding GO:0043388 57 41 2,000 4,517E-04 8,956E-03 ! regulation of epithelial cell differentiation GO:0030856 13 9 1,000 4,672E-04 9,184E-03 ! lung alveolus development GO:0048286 17 9 1,000 4,672E-04 9,106E-03 ! receptor clustering GO:0043113 15 9 1,000 4,672E-04 9,029E-03 ! postreplication repair GO:0006301 11 9 1,000 4,672E-04 8,954E-03 ! regulation of RNA splicing GO:0043484 14 9 1,000 4,672E-04 8,88E-03 ! positive regulation of protein polymerization GO:0032273 15 9 1,000 4,672E-04 8,807E-03 ! localization within membrane GO:0051668 15 9 1,000 4,672E-04 8,736E-03 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 3,000 4,922E-04 9,13E-03 ! positive regulation of binding GO:0051099 59 43 2,000 5,202E-04 9,571E-03 ! regulation of inflammatory response GO:0050727 60 44 2,000 5,568E-04 0,01016354 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 5,568E-04 0,01008351 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 5,826E-04 0,01046829 ! blood vessel remodeling GO:0001974 21 10 1,000 5,826E-04 0,01038714 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 5,826E-04 0,01030724 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 5,826E-04 0,01022856 ! regulation of bone resorption GO:0045124 24 10 1,000 5,826E-04 0,01015107 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 5,826E-04 0,01007474 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 5,826E-04 1E-02 ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 5,826E-04 9,925E-03 ! positive regulation of cell cycle GO:0045787 77 45 2,000 5,95E-04 0,01006255 ! RNA catabolic process GO:0006401 64 45 2,000 5,95E-04 9,989E-03 ! positive regulation of defense response GO:0031349 59 45 2,000 5,95E-04 9,917E-03 ! regulation of ossification GO:0030278 71 46 2,000 6,349E-04 0,01050484 ! regulation of adaptive immune response GO:0002819 72 46 2,000 6,349E-04 0,01042981 ! response to UV GO:0009411 75 46 2,000 6,349E-04 0,01035584 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 6,764E-04 0,01095543 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 7,104E-04 0,01142546 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 7,104E-04 0,01134612 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 7,104E-04 0,01126787 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 7,104E-04 0,01119069 ! plasma membrane organization GO:0007009 18 11 1,000 7,104E-04 0,01111456 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 7,104E-04 0,01103946 ! temperature homeostasis GO:0001659 16 11 1,000 7,104E-04 0,01096537 ! regulation of leukocyte migration GO:0002685 24 11 1,000 7,104E-04 0,01089227 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 1,000 7,104E-04 0,01082014 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cellular polysaccharide metabolic process GO:0044264 63 48 2,000 7,196E-04 0,01088858 ! non-recombinational repair GO:0000726 19 12 1,000 8,504E-04 0,0127842 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 1,000 8,504E-04 0,01270119 ! immunoglobulin production during immune response GO:0002381 20 12 1,000 8,504E-04 0,01261925 ! histone acetylation GO:0016573 23 12 1,000 8,504E-04 0,01253835 ! gland morphogenesis GO:0022612 23 12 1,000 8,504E-04 0,01245849 ! peptidyl-lysine modification GO:0018205 18 12 1,000 8,504E-04 0,01237964 ! regulation of mRNA stability GO:0043488 27 12 1,000 8,504E-04 0,01230178 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 8,504E-04 0,0122249 ! positive regulation of cell migration GO:0030335 92 51 2,000 8,597E-04 0,01228102 ! positive regulation of organelle organization GO:0010638 82 51 2,000 8,597E-04 0,01220521 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,003E-03 0,01414825 ! positive regulation of protein complex assembly GO:0031334 19 13 1,000 1,003E-03 0,01406198 ! lipid localization GO:0010876 24 13 1,000 1,003E-03 0,01397675 GO:0019915|lipid storage, ! organelle fusion GO:0048284 28 13 1,000 1,003E-03 0,01389256 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 1,003E-03 0,01380937 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 1,003E-03 0,01372717 ! regulation of RNA stability GO:0043487 28 13 1,000 1,003E-03 0,01364594 ! nucleoside metabolic process GO:0009116 69 55 2,000 1,072E-03 0,01450055 ! positive regulation of cell motion GO:0051272 99 56 2,000 1,13E-03 0,01519215 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,167E-03 0,0156057 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 1,167E-03 0,0155155 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 1,000 1,167E-03 0,01542633 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 1,000 1,167E-03 0,01533818 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! lung development GO:0030324 94 59 2,000 1,314E-03 0,01717603 ! negative regulation of hormone secretion GO:0046888 20 15 1,000 1,343E-03 0,01745667 ! lipid phosphorylation GO:0046834 23 15 1,000 1,343E-03 0,0173586 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 1,000 1,343E-03 0,01726162 ! regulation of vasodilation GO:0042312 24 15 1,000 1,343E-03 0,01716573 ! neuron recognition GO:0008038 22 15 1,000 1,343E-03 0,01707089 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 1,343E-03 0,01697709 ! respiratory tube development GO:0030323 99 62 2,000 1,517E-03 0,01906837 ! protein amino acid acetylation GO:0006473 28 16 1,000 1,532E-03 0,01914627 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 1,000 1,532E-03 0,01904277 ! oogenesis GO:0048477 23 16 1,000 1,532E-03 0,01894039 ! regulation of transcription factor activity GO:0051090 97 63 2,000 1,589E-03 0,01954263 GO:0090046|regulation of transcription regulator activity, ! respiratory system development GO:0060541 100 64 2,000 1,663E-03 0,02034173 ! adaptive immune response GO:0002250 94 64 2,000 1,663E-03 0,0202341 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! signal complex assembly GO:0007172 29 17 1,000 1,732E-03 0,02096435 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 1,732E-03 0,02085459 ! inactivation of MAPK activity GO:0000188 27 17 1,000 1,732E-03 0,02074598 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 1,732E-03 0,02063848 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 1,732E-03 0,0205321 ! sensory perception of pain GO:0019233 23 17 1,000 1,732E-03 0,02042681 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 1,732E-03 0,02032259 ! regulation of MAPKKK cascade GO:0043408 101 65 2,000 1,739E-03 0,02029889 ! positive regulation of T cell activation GO:0050870 94 65 2,000 1,739E-03 0,02019637 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 1,944E-03 0,0224652 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 1,944E-03 0,02235288 ! positive regulation of cytoskeleton organization GO:0051495 33 18 1,000 1,944E-03 0,02224167 ! somitogenesis GO:0001756 24 18 1,000 1,944E-03 0,02213156 ! reciprocal meiotic recombination GO:0007131 31 19 1,000 2,167E-03 0,02455546 ! regeneration GO:0031099 32 19 1,000 2,167E-03 0,02443509 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 2,167E-03 0,02431589 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 2,167E-03 0,02419786 ! regulation of interleukin-2 production GO:0032663 31 19 1,000 2,167E-03 0,02408096 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 2,167E-03 0,02396518 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 2,167E-03 0,02385052 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 2,167E-03 0,02373694 ! protein stabilization GO:0050821 26 19 1,000 2,167E-03 0,02362445 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 2,402E-03 0,02606406 ! positive regulation of locomotion GO:0040017 35 20 1,000 2,402E-03 0,02594169 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of transport GO:0051051 116 73 2,000 2,425E-03 0,02606025 ! positive regulation of lymphocyte activation GO:0051251 108 74 2,000 2,521E-03 0,02696495 ! protein amino acid acylation GO:0043543 37 21 1,000 2,649E-03 0,02820762 ! regulation of chemotaxis GO:0050920 36 21 1,000 2,649E-03 0,02807763 ! vesicle docking GO:0048278 27 21 1,000 2,649E-03 0,02794883 ! regulation of DNA recombination GO:0000018 40 21 1,000 2,649E-03 0,02782121 ! regulation of vasoconstriction GO:0019229 31 21 1,000 2,649E-03 0,02769475 ! platelet activation GO:0030168 28 21 1,000 2,649E-03 0,02756944 ! tRNA metabolic process GO:0006399 95 76 2,000 2,719E-03 0,0281741 ! gland development GO:0048732 148 77 2,000 2,822E-03 0,02910919 ! regulation of smooth muscle contraction GO:0006940 36 22 1,000 2,907E-03 0,02984982 ! regulation of behavior GO:0050795 38 22 1,000 2,907E-03 0,02971715 ! membrane depolarization GO:0051899 35 22 1,000 2,907E-03 0,02958566 ! regulation of blood coagulation GO:0030193 34 22 1,000 2,907E-03 0,02945533 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 3,176E-03 0,03204354 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 3,176E-03 0,03190361 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 1,000 3,176E-03 0,0317649 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! negative regulation of catabolic process GO:0009895 34 23 1,000 3,176E-03 0,03162739 ! positive regulation of cell activation GO:0050867 120 81 2,000 3,258E-03 0,03229809 GO:0002696|positive regulation of leukocyte activation, ! insulin receptor signaling pathway GO:0008286 40 24 1,000 3,457E-03 0,034126 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 1,000 3,457E-03 0,03398016 ! receptor metabolic process GO:0043112 37 24 1,000 3,457E-03 0,03383556 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 1,000 3,457E-03 0,03369219 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 3,457E-03 0,03355003 ! regulation of defense response GO:0031347 117 84 2,000 3,61E-03 0,03488821 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 3,733E-03 0,03592006 ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 3,749E-03 0,03592691 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 3,749E-03 0,03577783 ! positive regulation of nuclear division GO:0051785 39 25 1,000 3,749E-03 0,03562999 GO:0045840|positive regulation of mitosis, ! skeletal muscle tissue development GO:0007519 123 87 2,000 3,985E-03 0,03771707 GO:0060538|skeletal muscle organ development, ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 4,052E-03 0,03819278 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 4,052E-03 0,03803689 ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 4,052E-03 0,03788227 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 4,052E-03 0,0377289 ! regulation of coagulation GO:0050818 39 26 1,000 4,052E-03 0,03757677 ! regulation of T cell activation GO:0050863 128 89 2,000 4,247E-03 0,03923284 ! membrane docking GO:0022406 39 27 1,000 4,366E-03 0,04016363 ! acute-phase response GO:0006953 42 27 1,000 4,366E-03 0,04000362 ! respiratory gaseous exchange GO:0007585 47 27 1,000 4,366E-03 0,03984488 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 4,366E-03 0,03968739 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 1,000 4,366E-03 0,03953114 ! positive regulation of immune response GO:0050778 121 92 2,000 4,66E-03 0,04203531 ! DNA recombination GO:0006310 146 92 2,000 4,66E-03 0,04187111 ! cholesterol homeostasis GO:0042632 46 28 1,000 4,69E-03 0,04197619 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 34 28 1,000 4,69E-03 0,04181349 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 4,69E-03 0,04165205 ! sterol biosynthetic process GO:0016126 40 28 1,000 4,69E-03 0,04149185 ! polysaccharide metabolic process GO:0005976 129 93 2,000 4,803E-03 0,04232821 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 5,026E-03 0,04412125 ! response to light stimulus GO:0009416 153 96 2,000 5,248E-03 0,04589365 ! cholesterol transport GO:0030301 46 30 1,000 5,372E-03 0,04680447 GO:0015918|sterol transport, ! spindle organization GO:0007051 37 30 1,000 5,372E-03 0,04662785 ! regulation of microtubule-based process GO:0032886 58 30 1,000 5,372E-03 0,04645255 ! calcium ion transport GO:0006816 167 99 2,000 5,716E-03 0,04924208 ! negative regulation of secretion GO:0051048 49 31 1,000 5,729E-03 0,04916991 ! mammary gland development GO:0030879 57 31 1,000 5,729E-03 0,04898712 ! maintenance of protein location in cell GO:0032507 60 31 1,000 5,729E-03 0,04880568 ! segmentation GO:0035282 41 31 1,000 5,729E-03 0,04862559 ! divalent metal ion transport GO:0070838 171 100 2,000 5,878E-03 0,04970312 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 6,097E-03 0,05136647 ! meiosis I GO:0007127 52 32 1,000 6,097E-03 0,051179 ! neutral lipid metabolic process GO:0006638 41 32 1,000 6,097E-03 0,0509929 GO:0006639|acylglycerol metabolic process, ! regulation of protein stability GO:0031647 48 32 1,000 6,097E-03 0,05080814 ! calcium-mediated signaling GO:0019722 50 32 1,000 6,097E-03 0,05062472 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 6,475E-03 0,05357098 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of DNA binding GO:0043392 54 33 1,000 6,475E-03 0,05337897 ! lipid homeostasis GO:0055088 55 33 1,000 6,475E-03 0,05318833 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 6,864E-03 0,05617939 ! glycerol ether metabolic process GO:0006662 44 34 1,000 6,864E-03 0,05598018 ! neuron migration GO:0001764 46 34 1,000 6,864E-03 0,05578237 ! female gamete generation GO:0007292 43 34 1,000 6,864E-03 0,05558595 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 6,864E-03 0,05539091 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 7,263E-03 0,05840523 ! maintenance of protein location GO:0045185 65 35 1,000 7,263E-03 0,05820173 ! protein homooligomerization GO:0051260 52 35 1,000 7,263E-03 0,05799964 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 7,672E-03 0,0610554 GO:0090047|positive regulation of transcription regulator activity, ! regulation of hormone secretion GO:0046883 48 36 1,000 7,672E-03 0,06084486 ! negative regulation of binding GO:0051100 58 36 1,000 7,672E-03 0,06063577 ! organic ether metabolic process GO:0018904 46 36 1,000 7,672E-03 0,06042812 ! amino acid activation GO:0043038 52 37 1,000 8,091E-03 0,0635139 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! gliogenesis GO:0042063 71 38 1,000 8,521E-03 0,06665785 ! maintenance of location in cell GO:0051651 69 38 1,000 8,521E-03 0,06643189 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 9,41E-03 0,07311545 ! double-strand break repair GO:0006302 67 40 1,000 9,41E-03 0,07286927 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 9,41E-03 0,07262475 ! positive regulation of protein transport GO:0051222 55 40 1,000 9,41E-03 0,07238185 ! endosome transport GO:0016197 71 41 1,000 9,869E-03 0,07566252 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,01033822 0,07899635 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 1,000 0,01033822 0,07873477 ! regulation of cell shape GO:0008360 78 42 1,000 0,01033822 0,07847492 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 0,01081715 0,08184025 ! tRNA processing GO:0008033 49 43 1,000 0,01081715 0,08157193 ! vesicle organization GO:0016050 79 43 1,000 0,01081715 0,08130535 ! response to insulin stimulus GO:0032868 63 43 1,000 0,01081715 0,08104051 ! regulation of translational initiation GO:0006446 64 45 1,000 0,01180391 0,08814607 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,01180391 0,08786081 ! cell recognition GO:0008037 58 45 1,000 0,01180391 0,08757739 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,01180391 0,08729579 ! histone modification GO:0016570 68 46 1,000 0,01231159 0,09075854 ! covalent chromatin modification GO:0016569 75 47 1,000 0,01282871 0,0942685 ! regulation of protein polymerization GO:0032271 71 47 1,000 0,01282871 0,09396828 ! regulation of muscle contraction GO:0006937 69 48 1,000 0,0133552 0,09751414 ! immunoglobulin mediated immune response GO:0016064 66 48 1,000 0,0133552 0,09720555 GO:0019724|B cell mediated immunity, ! regulation of angiogenesis GO:0045765 94 49 1,000 0,01389097 0,10078622 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 1,000 0,01389097 0,10046928 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,01389097 0,10015433 ! maintenance of location GO:0051235 84 49 1,000 0,01389097 0,09984135 ! membrane fusion GO:0006944 80 50 1,000 0,01443596 0,10343523 ! lipid modification GO:0030258 73 50 1,000 0,01443596 0,103114 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 0,01499009 0,10674061 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,01499009 0,10641116 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,01499009 0,10608374 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,0155533 0,10973188 ! establishment of organelle localization GO:0051656 85 52 1,000 0,0155533 0,10939631 ! regulation of protein complex assembly GO:0043254 81 54 1,000 0,01670664 0,11715025 ! regulation of mitosis GO:0007088 84 54 1,000 0,01670664 0,11679417 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,01670664 0,11644025 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,01670664 0,11608847 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,01789542 0,12397431 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,01789542 0,12360202 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01817307 0,12514392 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01817307 0,12477035 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01817307 0,12439901 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01817307 0,12402988 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01817307 0,12366292 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01817307 0,12329814 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01817307 0,12293549 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01817307 0,12257498 ! sleep GO:0030431 11 5 0,000 0,01817307 0,12221657 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01817307 0,12186026 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01817307 0,12150601 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01817307 0,12115382 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01817307 0,12080366 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01817307 0,12045553 ! tongue development GO:0043586 6 5 0,000 0,01817307 0,12010939 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01817307 0,11976524 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01817307 0,11942305 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01817307 0,11908281 ! cobalt ion transport GO:0006824 9 5 0,000 0,01817307 0,11874451 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01817307 0,11840812 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01817307 0,11807364 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01817307 0,11774104 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01817307 0,1174103 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01817307 0,11708142 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01817307 0,11675438 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01817307 0,11642916 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01817307 0,11610574 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01817307 0,11578412 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01817307 0,11546428 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01817307 0,11514619 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01817307 0,11482986 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01817307 0,11451525 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01817307 0,11420237 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01817307 0,11389119 ! malate metabolic process GO:0006108 7 5 0,000 0,01817307 0,11358171 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01817307 0,1132739 ! behavioral response to pain GO:0048266 7 5 0,000 0,01817307 0,11296775 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01817307 0,11266326 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01817307 0,1123604 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01817307 0,11205916 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01817307 0,11175954 ! mating behavior GO:0007617 6 5 0,000 0,01817307 0,11146151 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01817307 0,11116507 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01817307 0,11087021 ! rhythmic behavior GO:0007622 12 5 0,000 0,01817307 0,1105769 ! copulation GO:0007620 7 5 0,000 0,01817307 0,11028514 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01817307 0,10999492 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01817307 0,10970622 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01817307 0,10941903 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01817307 0,10913334 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01817307 0,10884914 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01817307 0,10856641 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01817307 0,10828515 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01817307 0,10800534 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01817307 0,10772698 ! response to protozoan GO:0001562 9 5 0,000 0,01817307 0,10745005 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,01817307 0,10717453 ! lymph vessel development GO:0001945 7 5 0,000 0,01817307 0,10690043 ! endochondral ossification GO:0001958 12 5 0,000 0,01817307 0,10662772 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01817307 0,10635641 ! parathyroid gland development GO:0060017 8 5 0,000 0,01817307 0,10608647 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01817307 0,10581789 ! anagen GO:0042640 6 5 0,000 0,01817307 0,10555068 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01817307 0,10528481 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01817307 0,10502027 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01817307 0,10475706 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01817307 0,10449517 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01817307 0,10423458 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01817307 0,10397529 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01817307 0,10371729 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01817307 0,10346056 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01817307 0,10320511 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01817307 0,10295091 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01817307 0,10269796 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01817307 0,10244624 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01817307 0,10219577 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01817307 0,10194651 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01817307 0,10169846 ! ovulation GO:0030728 6 5 0,000 0,01817307 0,10145162 ! microvillus organization GO:0032528 7 5 0,000 0,01817307 0,10120598 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01817307 0,10096152 ! response to pH GO:0009268 9 5 0,000 0,01817307 0,10071824 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01817307 0,10047612 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01817307 0,10023517 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01817307 0,09999538 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01817307 0,09975673 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01817307 0,09951921 ! polyol catabolic process GO:0046174 7 5 0,000 0,01817307 0,09928282 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01817307 0,09904755 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01817307 0,0988134 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01817307 0,09858035 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01817307 0,0983484 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01817307 0,09811753 ! urea metabolic process GO:0019627 6 5 0,000 0,01817307 0,09788775 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01817307 0,09765904 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01817307 0,09743139 ! neutrophil activation GO:0042119 5 5 0,000 0,01817307 0,09720481 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01817307 0,09697928 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01817307 0,09675479 ! response to food GO:0032094 5 5 0,000 0,01817307 0,09653133 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01817307 0,09630891 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01817307 0,09608751 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01817307 0,09586713 ! forebrain neuron development GO:0021884 7 5 0,000 0,01817307 0,09564775 ! melanosome organization GO:0032438 7 5 0,000 0,01817307 0,09542938 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01817307 0,095212 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01817307 0,09499561 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01817307 0,0947802 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01817307 0,09456576 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01817307 0,0943523 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01817307 0,09413979 ! nucleoside transport GO:0015858 6 5 0,000 0,01817307 0,09392824 ! nucleoside salvage GO:0043174 7 5 0,000 0,01817307 0,09371764 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01817307 0,09350798 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01817307 0,09329926 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01817307 0,09309147 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01817307 0,0928846 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01817307 0,09267864 ! depyrimidination GO:0045008 8 5 0,000 0,01817307 0,0924736 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01817307 0,09226947 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01817307 0,09206623 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01817307 0,09186389 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01817307 0,09166243 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01817307 0,09146186 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01817307 0,09126216 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01817307 0,09106333 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01817307 0,09086537 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01817307 0,09066826 ! monocyte differentiation GO:0030224 8 5 0,000 0,01817307 0,09047201 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01817307 0,0902766 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01817307 0,09008204 ! centrosome duplication GO:0051298 5 5 0,000 0,01817307 0,08988832 ! response to UV-C GO:0010225 6 5 0,000 0,01817307 0,08969542 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01817307 0,08950336 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01817307 0,08931211 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01817307 0,08912168 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01817307 0,08893206 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01817307 0,08874324 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01817307 0,08855523 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01817307 0,08836801 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01817307 0,08818158 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01817307 0,08799593 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01817307 0,08781107 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01817307 0,08762698 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01817307 0,08744366 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01817307 0,0872611 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01817307 0,08707931 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01817307 0,08689827 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01817307 0,08671798 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01817307 0,08653844 ! neural tube patterning GO:0021532 6 5 0,000 0,01817307 0,08635964 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01817307 0,08618158 ! histone demethylation GO:0016577 9 5 0,000 0,01817307 0,08600426 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01817307 0,08582765 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01817307 0,08565178 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01817307 0,08547662 ! enteric nervous system development GO:0048484 8 5 0,000 0,01817307 0,08530218 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01817307 0,08512845 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01817307 0,08495542 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01817307 0,0847831 ! transcription termination GO:0006353 8 5 0,000 0,01817307 0,08461147 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01817307 0,08444054 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01817307 0,0842703 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01817307 0,08410074 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,01817307 0,08393186 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01817307 0,08376366 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01817307 0,08359614 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01817307 0,08342928 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01817307 0,08326308 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01817307 0,08309755 ! apical protein localization GO:0045176 6 5 0,000 0,01817307 0,08293267 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01817307 0,08276845 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01817307 0,08260488 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01817307 0,08244195 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01817307 0,08227966 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01817307 0,08211801 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01817307 0,081957 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01817307 0,08179661 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01817307 0,08163685 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01817307 0,08147772 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01817307 0,0813192 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01817307 0,0811613 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01817307 0,08100401 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01817307 0,08084733 ! neural plate development GO:0001840 6 5 0,000 0,01817307 0,08069125 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01817307 0,08053578 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01817307 0,0803809 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01817307 0,08022662 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01817307 0,08007293 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01817307 0,07991982 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01817307 0,07976731 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01817307 0,07961537 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01817307 0,07946401 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01817307 0,07931322 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01817307 0,07916301 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01817307 0,07901336 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01817307 0,07886428 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01817307 0,07871576 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01817307 0,0785678 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01817307 0,07842039 GO:0055081|anion homeostasis, ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,01850292 0,07969424 ! chromosome segregation GO:0007059 83 57 1,000 0,01850292 0,07954528 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,01850292 0,07939687 ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,01911907 0,08188802 ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,01911907 0,08173581 ! actin filament organization GO:0007015 95 59 1,000 0,0197438 0,08424998 ! nucleoside monophosphate metabolic process GO:0009123 95 59 1,000 0,0197438 0,08409396 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,02037704 0,08663065 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,02037704 0,08647082 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,02037704 0,08631157 ! meiosis GO:0007126 96 61 1,000 0,02101871 0,08886589 GO:0051327|M phase of meiotic cell cycle, ! urogenital system development GO:0001655 101 61 1,000 0,02101871 0,08870283 ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,02101871 0,08854037 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 0,02166877 0,09111181 ! meiotic cell cycle GO:0051321 97 62 1,000 0,02166877 0,09094555 ! organelle localization GO:0051640 96 62 1,000 0,02166877 0,09077989 ! tRNA transcription GO:0009304 11 6 0,000 0,02176848 0,09103182 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02176848 0,09086661 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02176848 0,090702 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02176848 0,09053798 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02176848 0,09037455 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02176848 0,09021172 ! regulation of helicase activity GO:0051095 11 6 0,000 0,02176848 0,09004947 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02176848 0,0898878 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02176848 0,08972671 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02176848 0,0895662 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02176848 0,08940626 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02176848 0,08924689 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02176848 0,08908808 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02176848 0,08892985 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02176848 0,08877217 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02176848 0,08861505 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02176848 0,08845849 GO:0046463|acylglycerol biosynthetic process, ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02176848 0,08830248 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02176848 0,08814701 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02176848 0,0879921 ! neuron adhesion GO:0007158 9 6 0,000 0,02176848 0,08783773 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02176848 0,08768389 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02176848 0,0875306 ! signal peptide processing GO:0006465 8 6 0,000 0,02176848 0,08737784 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02176848 0,08722562 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02176848 0,08707392 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02176848 0,08692275 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02176848 0,0867721 ! opsonization GO:0008228 8 6 0,000 0,02176848 0,08662198 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02176848 0,08647237 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02176848 0,08632328 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02176848 0,0861747 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02176848 0,08602664 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02176848 0,08587908 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02176848 0,08573203 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02176848 0,08558548 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02176848 0,08543943 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02176848 0,08529387 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02176848 0,08514882 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02176848 0,08500425 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02176848 0,08486018 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02176848 0,08471659 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02176848 0,08457349 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02176848 0,08443087 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02176848 0,08428873 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02176848 0,08414706 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02176848 0,08400588 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02176848 0,08386516 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02176848 0,08372492 ! thymic T cell selection GO:0045061 12 6 0,000 0,02176848 0,08358515 ! protein lipoylation GO:0009249 10 6 0,000 0,02176848 0,08344584 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02176848 0,08330699 ! pigment granule organization GO:0048753 11 6 0,000 0,02176848 0,08316861 ! drug transport GO:0015893 6 6 0,000 0,02176848 0,08303069 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02176848 0,08289322 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02176848 0,0827562 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02176848 0,08261964 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02176848 0,08248353 ! histidine metabolic process GO:0006547 6 6 0,000 0,02176848 0,08234787 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02176848 0,08221265 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02176848 0,08207787 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02176848 0,08194354 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02176848 0,08180965 ! adenohypophysis development GO:0021984 10 6 0,000 0,02176848 0,08167619 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02176848 0,08154317 ! hyperosmotic response GO:0006972 8 6 0,000 0,02176848 0,08141057 ! microtubule nucleation GO:0007020 10 6 0,000 0,02176848 0,08127841 ! ER overload response GO:0006983 7 6 0,000 0,02176848 0,08114668 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02176848 0,08101538 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02176848 0,0808845 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02176848 0,08075404 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02176848 0,080624 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02176848 0,08049438 ! response to dietary excess GO:0002021 7 6 0,000 0,02176848 0,08036517 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02176848 0,08023638 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02176848 0,08010801 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02176848 0,07998004 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02176848 0,07985248 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02176848 0,07972532 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02176848 0,07959857 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02176848 0,07947223 ! neuron apoptosis GO:0051402 8 6 0,000 0,02176848 0,07934628 ! organic alcohol transport GO:0015850 9 6 0,000 0,02176848 0,07922073 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02176848 0,07909558 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02176848 0,07897083 ! male sex determination GO:0030238 9 6 0,000 0,02176848 0,07884646 ! carnitine transport GO:0015879 8 6 0,000 0,02176848 0,07872249 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02176848 0,07859891 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02176848 0,07847571 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02176848 0,0783529 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02176848 0,07823047 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02176848 0,07810843 ! parturition GO:0007567 12 6 0,000 0,02176848 0,07798677 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02176848 0,07786548 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02176848 0,07774457 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02176848 0,07762404 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02176848 0,07750388 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02176848 0,07738409 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02176848 0,07726467 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02176848 0,07714561 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02176848 0,07702693 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02176848 0,07690861 ! macrophage differentiation GO:0030225 10 6 0,000 0,02176848 0,07679065 ! astrocyte development GO:0014002 14 6 0,000 0,02176848 0,07667305 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02176848 0,07655582 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02176848 0,07643894 ! interaction with symbiont GO:0051702 8 6 0,000 0,02176848 0,07632241 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02176848 0,07620625 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02176848 0,07609043 ! eating behavior GO:0042755 6 6 0,000 0,02176848 0,07597497 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02176848 0,07585985 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02176848 0,07574509 ! response to copper ion GO:0046688 9 6 0,000 0,02176848 0,07563067 ! DNA topological change GO:0006265 8 6 0,000 0,02176848 0,0755166 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02176848 0,07540287 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02176848 0,07528948 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02176848 0,07517643 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02176848 0,07506372 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02176848 0,07495135 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02176848 0,07483932 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02176848 0,07472762 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02176848 0,07461625 ! hair follicle maturation GO:0048820 7 6 0,000 0,02176848 0,07450521 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02176848 0,07439451 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02176848 0,07428413 ! Schwann cell development GO:0014044 14 6 0,000 0,02176848 0,07417408 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02176848 0,07406435 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02176848 0,07395495 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02176848 0,07384588 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02176848 0,07373712 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02176848 0,07362868 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02176848 0,07352056 ! histone ubiquitination GO:0016574 7 6 0,000 0,02176848 0,07341276 ! regulation of meiosis GO:0040020 10 6 0,000 0,02176848 0,07330528 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02176848 0,0731981 GO:0000085|G2 phase of mitotic cell cycle, ! regulation of cell division GO:0051302 8 6 0,000 0,02176848 0,07309125 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02176848 0,0729847 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02176848 0,07287846 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02176848 0,07277253 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02176848 0,07266691 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02176848 0,0725616 ! receptor internalization GO:0031623 9 6 0,000 0,02176848 0,07245659 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02176848 0,07235188 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02176848 0,07224748 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02176848 0,07214338 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02176848 0,07203957 ! protein deubiquitination GO:0016579 8 6 0,000 0,02176848 0,07193607 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02176848 0,07183286 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02176848 0,07172995 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02176848 0,07162733 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02176848 0,071525 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02176848 0,07142297 ! midbrain development GO:0030901 6 6 0,000 0,02176848 0,07132123 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02176848 0,07121978 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02176848 0,07111861 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02176848 0,07101774 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02176848 0,07091714 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02176848 0,07081684 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02176848 0,07071681 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02176848 0,07061707 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02176848 0,07051761 ! adult feeding behavior GO:0008343 6 6 0,000 0,02176848 0,07041843 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02176848 0,07031953 ! blastocyst growth GO:0001832 15 6 0,000 0,02176848 0,0702209 ! pigment granule transport GO:0051904 12 6 0,000 0,02176848 0,07012255 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02176848 0,07002448 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02176848 0,06992668 ! catecholamine transport GO:0051937 7 6 0,000 0,02176848 0,06982915 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02176848 0,0697319 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02176848 0,06963491 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02176848 0,0695382 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02176848 0,06944175 ! protein prenylation GO:0018342 10 6 0,000 0,02176848 0,06934557 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02176848 0,06924966 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02176848 0,06915401 ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,02232712 0,07083087 ! regulation of lipase activity GO:0060191 109 63 1,000 0,02232712 0,07073331 ! reproductive structure development GO:0048608 90 65 1,000 0,02366848 0,07487965 ! B cell activation GO:0042113 104 65 1,000 0,02366848 0,07477679 ! protein oligomerization GO:0051259 100 65 1,000 0,02366848 0,07467422 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02535093 0,07987278 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02535093 0,07976351 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02535093 0,07965455 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02535093 0,07954588 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02535093 0,0794375 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02535093 0,07932943 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02535093 0,07922164 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02535093 0,07911415 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02535093 0,07900695 ! reproductive behavior GO:0019098 12 7 0,000 0,02535093 0,07890004 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02535093 0,07879342 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,02535093 0,07868708 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02535093 0,07858104 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02535093 0,07847527 ! oligopeptide transport GO:0006857 11 7 0,000 0,02535093 0,0783698 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02535093 0,0782646 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02535093 0,07815969 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,02535093 0,07805506 ! pericardium development GO:0060039 8 7 0,000 0,02535093 0,07795071 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02535093 0,07784663 ! fibril organization GO:0043206 13 7 0,000 0,02535093 0,07774284 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02535093 0,07763932 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02535093 0,07753607 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02535093 0,0774331 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02535093 0,07733041 ! lipoprotein transport GO:0042953 9 7 0,000 0,02535093 0,07722798 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02535093 0,07712583 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02535093 0,07702395 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02535093 0,07692233 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02535093 0,07682099 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02535093 0,07671991 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02535093 0,07661909 ! chemosensory behavior GO:0007635 9 7 0,000 0,02535093 0,07651854 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02535093 0,07641825 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02535093 0,07631823 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02535093 0,07621847 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02535093 0,07611897 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02535093 0,07601972 ! reflex GO:0060004 12 7 0,000 0,02535093 0,07592074 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02535093 0,07582201 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02535093 0,07572354 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02535093 0,07562533 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02535093 0,07552737 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02535093 0,07542966 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02535093 0,07533221 ! spinal cord patterning GO:0021511 7 7 0,000 0,02535093 0,075235 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02535093 0,07513805 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02535093 0,07504135 ! adrenal gland development GO:0030325 17 7 0,000 0,02535093 0,07494489 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02535093 0,07484869 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02535093 0,07475273 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02535093 0,07465701 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02535093 0,07456154 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02535093 0,07446632 ! endosome organization GO:0007032 10 7 0,000 0,02535093 0,07437134 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02535093 0,0742766 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02535093 0,0741821 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02535093 0,07408784 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02535093 0,07399382 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02535093 0,07390004 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02535093 0,07380649 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02535093 0,07371318 ! galactose metabolic process GO:0006012 10 7 0,000 0,02535093 0,07362011 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02535093 0,07352727 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02535093 0,07343467 ! organ growth GO:0035265 11 7 0,000 0,02535093 0,0733423 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02535093 0,07325016 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,02535093 0,07315825 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02535093 0,07306658 ! retinol metabolic process GO:0042572 9 7 0,000 0,02535093 0,07297513 ! behavioral fear response GO:0001662 13 7 0,000 0,02535093 0,07288391 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02535093 0,07279292 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02535093 0,07270215 ! rRNA modification GO:0000154 12 7 0,000 0,02535093 0,07261162 ! protein heterooligomerization GO:0051291 10 7 0,000 0,02535093 0,0725213 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02535093 0,07243121 ! response to UV-B GO:0010224 11 7 0,000 0,02535093 0,07234135 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,02535093 0,07225171 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02535093 0,07216229 ! intermediate filament organization GO:0045109 11 7 0,000 0,02535093 0,07207309 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02535093 0,07198411 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02535093 0,07189535 ! fibrinolysis GO:0042730 9 7 0,000 0,02535093 0,07180681 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,02535093 0,07171848 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02535093 0,07163038 ! B cell lineage commitment GO:0002326 17 7 0,000 0,02535093 0,07154249 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02535093 0,07145481 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02535093 0,07136735 ! response to tropane GO:0014073 13 7 0,000 0,02535093 0,07128011 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02535093 0,07119307 ! melanosome localization GO:0032400 10 7 0,000 0,02535093 0,07110625 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02535093 0,07101964 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02535093 0,07093325 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02535093 0,07084706 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02535093 0,07076108 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02535093 0,07067531 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02535093 0,07058974 ! mast cell activation GO:0045576 9 7 0,000 0,02535093 0,07050439 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02535093 0,07041924 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02535093 0,07033429 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02535093 0,07024955 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02535093 0,07016502 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02535093 0,07008068 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,02535093 0,06999655 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,02535093 0,06991262 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02535093 0,0698289 ! T cell lineage commitment GO:0002360 12 7 0,000 0,02535093 0,06974537 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02535093 0,06966204 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02535093 0,06957891 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02535093 0,06949598 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02535093 0,06941325 ! response to tumor cell GO:0002347 12 7 0,000 0,02535093 0,06933071 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02535093 0,06924837 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02535093 0,06916623 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02535093 0,06908427 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02535093 0,06900252 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02535093 0,06892096 ! diuresis GO:0030146 12 7 0,000 0,02535093 0,06883958 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02535093 0,06875841 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02535093 0,06867742 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02535093 0,06859662 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02535093 0,06851601 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02535093 0,0684356 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02535093 0,06835537 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02535093 0,06827533 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02535093 0,06819547 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02535093 0,0681158 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02535093 0,06803632 ! lymph node development GO:0048535 9 7 0,000 0,02535093 0,06795703 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02535093 0,06787791 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,02535093 0,06779899 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02535093 0,06772024 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02535093 0,06764168 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02535093 0,0675633 ! ATP catabolic process GO:0006200 10 7 0,000 0,02535093 0,0674851 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02535093 0,06740708 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02535093 0,06732925 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02535093 0,06725159 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02535093 0,06717411 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02535093 0,06709681 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02535093 0,06701969 ! muscle adaptation GO:0043500 12 7 0,000 0,02535093 0,06694274 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02535093 0,06686597 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02535093 0,06678938 ! retina homeostasis GO:0001895 9 7 0,000 0,02535093 0,06671296 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02535093 0,06663672 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02535093 0,06656065 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,02535093 0,06648475 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02535093 0,06640903 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02535093 0,06633348 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02535093 0,0662581 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02535093 0,06618289 ! acute inflammatory response GO:0002526 92 68 1,000 0,02574113 0,06712539 ! regulation of catabolic process GO:0009894 106 70 1,000 0,02716253 0,07075179 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,02788493 0,07255129 ! steroid biosynthetic process GO:0006694 94 71 1,000 0,02788493 0,07246931 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,02861504 0,07428283 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02892046 0,07499103 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02892046 0,07490659 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,02892046 0,07482233 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02892046 0,07473826 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02892046 0,07465437 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02892046 0,07457068 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02892046 0,07448718 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02892046 0,07440386 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02892046 0,07432072 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,02892046 0,07423778 ! phosphate transport GO:0006817 10 8 0,000 0,02892046 0,07415501 ! N-glycan processing GO:0006491 12 8 0,000 0,02892046 0,07407244 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02892046 0,07399004 ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02892046 0,07390783 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02892046 0,0738258 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02892046 0,07374396 ! succinate metabolic process GO:0006105 14 8 0,000 0,02892046 0,07366229 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,02892046 0,0735808 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02892046 0,0734995 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02892046 0,07341837 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02892046 0,07333743 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02892046 0,07325666 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02892046 0,07317607 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02892046 0,07309566 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02892046 0,07301542 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02892046 0,07293536 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02892046 0,07285547 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02892046 0,07277576 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02892046 0,07269623 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02892046 0,07261686 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02892046 0,07253767 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02892046 0,07245866 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02892046 0,07237981 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02892046 0,07230114 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02892046 0,07222264 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02892046 0,0721443 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02892046 0,07206614 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02892046 0,07198815 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02892046 0,07191032 ! melanin metabolic process GO:0006582 12 8 0,000 0,02892046 0,07183266 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02892046 0,07175518 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02892046 0,07167785 ! macrophage activation GO:0042116 12 8 0,000 0,02892046 0,0716007 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02892046 0,07152371 ! multicellular organism growth GO:0035264 14 8 0,000 0,02892046 0,07144688 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02892046 0,07137022 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02892046 0,07129373 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02892046 0,0712174 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02892046 0,07114123 ! ruffle organization GO:0031529 11 8 0,000 0,02892046 0,07106522 ! osteoblast development GO:0002076 13 8 0,000 0,02892046 0,07098938 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02892046 0,0709137 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02892046 0,07083818 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02892046 0,07076282 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02892046 0,07068762 GO:0007351|tripartite regional subdivision, ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02892046 0,07061258 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02892046 0,0705377 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02892046 0,07046297 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02892046 0,07038841 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02892046 0,070314 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02892046 0,07023975 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02892046 0,07016566 ! segment specification GO:0007379 10 8 0,000 0,02892046 0,07009173 ! cellular extravasation GO:0045123 11 8 0,000 0,02892046 0,07001794 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02892046 0,06994432 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02892046 0,06987085 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02892046 0,06979753 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,02892046 0,06972437 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02892046 0,06965136 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02892046 0,0695785 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02892046 0,0695058 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02892046 0,06943324 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02892046 0,06936084 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02892046 0,06928859 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02892046 0,06921649 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02892046 0,06914454 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02892046 0,06907274 ! icosanoid secretion GO:0032309 12 8 0,000 0,02892046 0,06900109 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,02892046 0,06892958 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02892046 0,06885823 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02892046 0,06878702 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02892046 0,06871596 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02892046 0,06864504 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02892046 0,06857428 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02892046 0,06850365 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02892046 0,06843318 ! sterol catabolic process GO:0016127 9 8 0,000 0,02892046 0,06836284 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02892046 0,06829266 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02892046 0,06822261 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02892046 0,06815271 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02892046 0,06808296 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02892046 0,06801334 ! S phase GO:0051320 8 8 0,000 0,02892046 0,06794387 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02892046 0,06787454 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02892046 0,06780535 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02892046 0,0677363 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02892046 0,06766739 ! hormone catabolic process GO:0042447 13 8 0,000 0,02892046 0,06759863 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02892046 0,06753 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02892046 0,06746151 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02892046 0,06739316 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02892046 0,06732495 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02892046 0,06725687 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02892046 0,06718894 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02892046 0,06712114 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02892046 0,06705348 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02892046 0,06698595 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02892046 0,06691856 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02892046 0,0668513 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02892046 0,06678418 ! regulation of embryonic development GO:0045995 16 8 0,000 0,02892046 0,0667172 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02892046 0,06665035 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02892046 0,06658363 ! protein import into nucleus GO:0006606 118 74 1,000 0,03009813 0,0692257 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,03009813 0,06915655 ! blood coagulation GO:0007596 116 75 1,000 0,03085099 0,07081564 GO:0050817|coagulation, ! nuclear import GO:0051170 121 75 1,000 0,03085099 0,07074504 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,0316113 0,07241633 ! regulation of protein transport GO:0051223 114 76 1,000 0,0316113 0,07234427 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,03237901 0,07402755 ! sex differentiation GO:0007548 105 77 1,000 0,03237901 0,07395404 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03247712 0,07410453 ! regulation of developmental growth GO:0048638 13 9 0,000 0,03247712 0,07403109 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,03247712 0,07395779 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03247712 0,07388464 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03247712 0,07381163 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03247712 0,07373876 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03247712 0,07366604 GO:0010469|regulation of receptor activity, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03247712 0,07359347 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03247712 0,07352103 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03247712 0,07344874 ! social behavior GO:0035176 14 9 0,000 0,03247712 0,07337659 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03247712 0,07330458 ! artery development GO:0060840 19 9 0,000 0,03247712 0,07323271 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03247712 0,07316099 ! regulation of glycolysis GO:0006110 15 9 0,000 0,03247712 0,0730894 ! response to pain GO:0048265 16 9 0,000 0,03247712 0,07301795 ! protein complex disassembly GO:0043241 17 9 0,000 0,03247712 0,07294665 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03247712 0,07287548 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03247712 0,07280445 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03247712 0,07273356 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03247712 0,07266281 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,03247712 0,07259219 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03247712 0,07252172 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03247712 0,07245137 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03247712 0,07238117 ! protein targeting to ER GO:0045047 19 9 0,000 0,03247712 0,0723111 ! T cell selection GO:0045058 18 9 0,000 0,03247712 0,07224117 ! endoderm development GO:0007492 12 9 0,000 0,03247712 0,07217137 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03247712 0,07210171 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03247712 0,07203218 ! arginine catabolic process GO:0006527 10 9 0,000 0,03247712 0,07196278 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03247712 0,07189352 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03247712 0,07182439 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03247712 0,0717554 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03247712 0,07168653 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,03247712 0,0716178 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03247712 0,0715492 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03247712 0,07148073 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03247712 0,0714124 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03247712 0,07134419 ! mannose metabolic process GO:0006013 9 9 0,000 0,03247712 0,07127611 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03247712 0,07120817 ! epithelial cell development GO:0002064 10 9 0,000 0,03247712 0,07114035 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03247712 0,07107266 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03247712 0,0710051 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03247712 0,07093767 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03247712 0,07087037 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03247712 0,07080319 ! motor axon guidance GO:0008045 14 9 0,000 0,03247712 0,07073614 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03247712 0,07066922 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03247712 0,07060243 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03247712 0,07053576 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03247712 0,07046921 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03247712 0,0704028 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03247712 0,0703365 ! DNA ligation GO:0006266 14 9 0,000 0,03247712 0,07027034 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03247712 0,07020429 ! response to amine stimulus GO:0014075 13 9 0,000 0,03247712 0,07013837 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03247712 0,07007258 ! erythrocyte development GO:0048821 11 9 0,000 0,03247712 0,0700069 ! renal water homeostasis GO:0003091 14 9 0,000 0,03247712 0,06994136 ! mRNA cleavage GO:0006379 13 9 0,000 0,03247712 0,06987593 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03247712 0,06981062 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03247712 0,06974544 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03247712 0,06968038 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03247712 0,06961544 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03247712 0,06955062 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03247712 0,06948592 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03247712 0,06942135 ! acid secretion GO:0046717 14 9 0,000 0,03247712 0,06935689 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03247712 0,06929255 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03247712 0,06922833 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03247712 0,06916423 ! purine base metabolic process GO:0006144 18 9 0,000 0,03247712 0,06910025 ! oocyte differentiation GO:0009994 12 9 0,000 0,03247712 0,06903638 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03247712 0,06897264 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03247712 0,06890901 ! spleen development GO:0048536 15 9 0,000 0,03247712 0,0688455 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03247712 0,06878211 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03247712 0,06871883 ! detection of calcium ion GO:0005513 13 9 0,000 0,03247712 0,06865567 ! blastocyst formation GO:0001825 12 9 0,000 0,03247712 0,06859262 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03247712 0,06852969 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03247712 0,06846688 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03247712 0,06840418 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03247712 0,0683416 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03247712 0,06827913 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03247712 0,06821677 ! prepulse inhibition GO:0060134 14 9 0,000 0,03247712 0,06815453 ! embryonic placenta development GO:0001892 12 9 0,000 0,03247712 0,0680924 ! insulin secretion GO:0030073 17 9 0,000 0,03247712 0,06803039 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03247712 0,06796849 ! response to nicotine GO:0035094 16 9 0,000 0,03247712 0,0679067 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03247712 0,06784502 ! nucleus localization GO:0051647 15 9 0,000 0,03247712 0,06778345 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03247712 0,067722 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,03315405 0,06907093 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,03393635 0,07063675 ! regulation of lyase activity GO:0051339 133 79 1,000 0,03393635 0,07057288 ! ATP biosynthetic process GO:0006754 118 79 1,000 0,03393635 0,07050913 ! protein localization in nucleus GO:0034504 133 80 1,000 0,03472586 0,07208437 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,03552252 0,07367159 ! hemostasis GO:0007599 125 81 1,000 0,03552252 0,07360522 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,03552252 0,07353897 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03602095 0,07450377 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03602095 0,07443683 ! neuron fate specification GO:0048665 11 10 0,000 0,03602095 0,07437001 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03602095 0,07430331 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03602095 0,07423673 ! thyroid gland development GO:0030878 19 10 0,000 0,03602095 0,07417027 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,03602095 0,07410393 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03602095 0,07403771 ! synapsis GO:0007129 13 10 0,000 0,03602095 0,0739716 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03602095 0,07390561 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03602095 0,07383974 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03602095 0,07377399 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03602095 0,07370836 ! sulfate transport GO:0008272 12 10 0,000 0,03602095 0,07364284 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03602095 0,07357744 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03602095 0,07351215 ! androgen metabolic process GO:0008209 13 10 0,000 0,03602095 0,07344698 ! phospholipid efflux GO:0033700 16 10 0,000 0,03602095 0,07338192 ! hippocampus development GO:0021766 19 10 0,000 0,03602095 0,07331698 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03602095 0,07325216 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03602095 0,07318745 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03602095 0,07312285 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03602095 0,07305837 ! pathogenesis GO:0009405 13 10 0,000 0,03602095 0,072994 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03602095 0,07292975 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03602095 0,0728656 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03602095 0,07280158 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03602095 0,07273766 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03602095 0,07267385 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03602095 0,07261016 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03602095 0,07254658 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03602095 0,07248311 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03602095 0,07241975 ! response to X-ray GO:0010165 16 10 0,000 0,03602095 0,0723565 ! B cell proliferation GO:0042100 14 10 0,000 0,03602095 0,07229336 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03602095 0,07223033 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03602095 0,07216742 ! forebrain cell migration GO:0021885 17 10 0,000 0,03602095 0,07210461 ! lipid digestion GO:0044241 15 10 0,000 0,03602095 0,07204191 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03602095 0,07197932 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03602095 0,07191683 ! UV protection GO:0009650 14 10 0,000 0,03602095 0,07185446 ! entry into host cell GO:0030260 20 10 0,000 0,03602095 0,07179219 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03602095 0,07173004 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03602095 0,07166799 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03602095 0,07160604 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,03602095 0,07154421 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03602095 0,07148248 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03602095 0,07142086 ! regulation of organ growth GO:0046620 11 10 0,000 0,03602095 0,07135934 ! response to dsRNA GO:0043331 18 10 0,000 0,03602095 0,07129793 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03602095 0,07123662 ! embryonic axis specification GO:0000578 12 10 0,000 0,03602095 0,07117542 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03602095 0,07111433 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03602095 0,07105334 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03602095 0,07099245 ! cranial nerve development GO:0021545 12 10 0,000 0,03602095 0,07093167 ! fucose catabolic process GO:0019317 16 10 0,000 0,03602095 0,07087099 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03602095 0,07081042 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03602095 0,07074995 ! protein sumoylation GO:0016925 12 10 0,000 0,03602095 0,07068958 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03602095 0,07062932 ! zymogen activation GO:0031638 14 10 0,000 0,03602095 0,07056916 ! salivary gland development GO:0007431 22 10 0,000 0,03602095 0,0705091 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03602095 0,07044914 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03602095 0,07038929 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03602095 0,07032954 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03602095 0,07026988 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03602095 0,07021033 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03602095 0,07015088 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03602095 0,07009153 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,03602095 0,07003228 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03602095 0,06997314 ! detection of bacterium GO:0016045 10 10 0,000 0,03602095 0,06991409 ! embryonic gut development GO:0048566 11 10 0,000 0,03602095 0,06985514 ! activation of innate immune response GO:0002218 10 10 0,000 0,03602095 0,06979629 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03602095 0,06973754 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03602095 0,06967888 ! developmental induction GO:0031128 13 10 0,000 0,03602095 0,06962033 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03602095 0,06956187 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03602095 0,06950352 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03602095 0,06944526 ! ossification GO:0001503 134 82 1,000 0,03632626 0,06997521 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,03713703 0,07147712 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,03795475 0,07298991 ! sterol metabolic process GO:0016125 120 84 1,000 0,03795475 0,07292894 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,03877939 0,07445124 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,03877939 0,07438915 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,03877939 0,07432716 ! regulation of protein localization GO:0032880 132 85 1,000 0,03877939 0,07426527 ! regulation of membrane potential GO:0042391 128 85 1,000 0,03877939 0,07420348 ! rRNA transcription GO:0009303 17 11 0,000 0,03955201 0,07561898 ! respiratory burst GO:0045730 14 11 0,000 0,03955201 0,07555617 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03955201 0,07549347 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03955201 0,07543087 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03955201 0,07536837 ! virus-host interaction GO:0019048 17 11 0,000 0,03955201 0,07530598 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03955201 0,0752437 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03955201 0,07518151 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03955201 0,07511943 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03955201 0,07505745 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03955201 0,07499557 ! mating GO:0007618 14 11 0,000 0,03955201 0,0749338 ! T cell proliferation GO:0042098 20 11 0,000 0,03955201 0,07487212 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03955201 0,07481055 ! bone resorption GO:0045453 16 11 0,000 0,03955201 0,07474908 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03955201 0,07468771 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03955201 0,07462644 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03955201 0,07456527 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,03955201 0,0745042 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03955201 0,07444323 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03955201 0,07438236 ! syncytium formation GO:0006949 15 11 0,000 0,03955201 0,07432159 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03955201 0,07426092 ! focal adhesion formation GO:0048041 24 11 0,000 0,03955201 0,07420035 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03955201 0,07413988 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03955201 0,0740795 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,03955201 0,07401923 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,03955201 0,07395905 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03955201 0,07389897 ! adult heart development GO:0007512 11 11 0,000 0,03955201 0,07383898 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03955201 0,0737791 ! L-glutamate transport GO:0015813 16 11 0,000 0,03955201 0,07371931 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03955201 0,07365962 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03955201 0,07360002 ! stem cell development GO:0048864 29 11 0,000 0,03955201 0,07354052 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03955201 0,07348112 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03955201 0,07342181 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03955201 0,0733626 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03955201 0,07330349 ! vasoconstriction GO:0042310 15 11 0,000 0,03955201 0,07324447 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03955201 0,07318554 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03955201 0,07312671 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03955201 0,07306797 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03955201 0,07300933 ! ribosome assembly GO:0042255 13 11 0,000 0,03955201 0,07295078 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03955201 0,07289233 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03955201 0,07283397 ! chromatin silencing GO:0006342 19 11 0,000 0,03955201 0,0727757 ! nucleosome positioning GO:0016584 13 11 0,000 0,03955201 0,07271753 ! T cell homeostasis GO:0043029 20 11 0,000 0,03955201 0,07265945 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03955201 0,07260146 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03955201 0,07254356 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03955201 0,07248576 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03955201 0,07242805 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03955201 0,07237043 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03955201 0,0723129 ! oxygen transport GO:0015671 15 11 0,000 0,03955201 0,07225546 ! male genitalia development GO:0030539 13 11 0,000 0,03955201 0,07219812 ! cholesterol efflux GO:0033344 19 11 0,000 0,03955201 0,07214086 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03955201 0,0720837 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03955201 0,07202663 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03955201 0,07196964 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03955201 0,07191275 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03955201 0,07185595 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03955201 0,07179923 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,03955201 0,07174261 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,03955201 0,07168607 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03955201 0,07162963 ! lysogeny GO:0030069 18 11 0,000 0,03955201 0,07157327 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03955201 0,071517 ! acrosome reaction GO:0007340 13 11 0,000 0,03955201 0,07146082 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03955201 0,07140473 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,03961086 0,07145489 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 0,03961086 0,07139889 ! interphase GO:0051325 159 88 1,000 0,0412941 0,07437465 ! reproductive developmental process GO:0003006 127 89 1,000 0,04214575 0,07584916 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,04214575 0,07578986 ! lactation GO:0007595 20 12 0,000 0,04307034 0,07739201 ! reproductive cellular process GO:0048610 14 12 0,000 0,04307034 0,0773316 ! tRNA modification GO:0006400 14 12 0,000 0,04307034 0,07727128 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,04307034 0,07721105 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,04307034 0,07715092 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,04307034 0,07709088 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,04307034 0,07703093 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,04307034 0,07697108 ! phospholipid catabolic process GO:0009395 14 12 0,000 0,04307034 0,07691132 ! peroxisomal transport GO:0043574 21 12 0,000 0,04307034 0,07685165 ! cartilage condensation GO:0001502 18 12 0,000 0,04307034 0,07679208 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,04307034 0,07673259 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,04307034 0,0766732 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,04307034 0,0766139 ! heart looping GO:0001947 15 12 0,000 0,04307034 0,0765547 ! palate development GO:0060021 15 12 0,000 0,04307034 0,07649558 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,04307034 0,07643656 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,04307034 0,07637762 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,04307034 0,07631878 ! arginine metabolic process GO:0006525 13 12 0,000 0,04307034 0,07626003 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,04307034 0,07620137 ! methionine metabolic process GO:0006555 13 12 0,000 0,04307034 0,0761428 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,04307034 0,07608431 ! Golgi organization GO:0007030 18 12 0,000 0,04307034 0,07602592 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,04307034 0,07596762 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,04307034 0,07590941 ! monoamine transport GO:0015844 13 12 0,000 0,04307034 0,07585128 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04307034 0,07579325 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,04307034 0,0757353 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,04307034 0,07567745 ! L-amino acid transport GO:0015807 20 12 0,000 0,04307034 0,07561968 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,04307034 0,075562 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,04307034 0,0755044 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,04307034 0,0754469 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,04307034 0,07538948 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,04307034 0,07533215 ! cerebellum development GO:0021549 13 12 0,000 0,04307034 0,07527491 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,04307034 0,07521775 ! histone methylation GO:0016571 15 12 0,000 0,04307034 0,07516068 ! autonomic nervous system development GO:0048483 23 12 0,000 0,04307034 0,0751037 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,04307034 0,0750468 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,04307034 0,07498999 ! response to gamma radiation GO:0010332 20 12 0,000 0,04307034 0,07493327 ! intestinal absorption GO:0050892 19 12 0,000 0,04307034 0,07487663 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,04307034 0,07482007 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,04307034 0,07476361 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,04307034 0,07470722 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,04307034 0,07465092 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,04307034 0,07459471 ! microspike assembly GO:0030035 23 12 0,000 0,04307034 0,07453858 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,04307034 0,07448254 ! response to cold GO:0009409 14 12 0,000 0,04307034 0,07442658 ! ATP metabolic process GO:0046034 137 91 1,000 0,04386881 0,07574945 ! response to virus GO:0009615 122 91 1,000 0,04386881 0,07569262 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,04474011 0,07713812 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,04474011 0,07708034 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,04561784 0,07853371 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,04561784 0,07847497 ! electron transport chain GO:0022900 123 94 1,000 0,04650195 0,07993609 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04657598 0,08000354 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04657598 0,07994384 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,04657598 0,07988422 ! water transport GO:0006833 17 13 0,000 0,04657598 0,0798247 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04657598 0,07976526 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04657598 0,07970591 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04657598 0,07964665 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04657598 0,07958748 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04657598 0,07952839 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04657598 0,0794694 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,04657598 0,07941049 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,04657598 0,07935166 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04657598 0,07929293 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04657598 0,07923428 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04657598 0,07917572 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04657598 0,07911724 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04657598 0,07905885 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04657598 0,07900055 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04657598 0,07894233 ! NAD metabolic process GO:0019674 21 13 0,000 0,04657598 0,0788842 ! exocrine system development GO:0035272 27 13 0,000 0,04657598 0,07882616 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04657598 0,07876819 ! bone mineralization GO:0030282 15 13 0,000 0,04657598 0,07871032 ! regulation of exocytosis GO:0017157 17 13 0,000 0,04657598 0,07865253 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,04657598 0,07859482 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04657598 0,0785372 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04657598 0,07847967 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,04657598 0,07842221 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,04657598 0,07836485 ! genitalia development GO:0048806 15 13 0,000 0,04657598 0,07830756 ! regulation of cellular pH GO:0030641 20 13 0,000 0,04657598 0,07825036 ! cellular pigmentation GO:0033059 24 13 0,000 0,04657598 0,07819324 ! tissue regeneration GO:0042246 21 13 0,000 0,04657598 0,07813621 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04657598 0,07807926 ! cofactor transport GO:0051181 19 13 0,000 0,04657598 0,07802239 ! NADP metabolic process GO:0006739 18 13 0,000 0,04657598 0,07796561 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04657598 0,07790891 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04657598 0,07785229 ! gas transport GO:0015669 18 13 0,000 0,04657598 0,07779575 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04657598 0,07773929 ! regulation of axon extension GO:0030516 23 13 0,000 0,04657598 0,07768292 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04657598 0,07762663 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04657598 0,07757042 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04657598 0,07751429 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04657598 0,07745824 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04657598 0,07740227 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04657598 0,07734639 ! angiogenesis GO:0001525 149 95 1,000 0,04739238 0,07864536 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,04828907 0,0800756 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,04919197 0,08151407 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,05006897 0,08290758 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,05006897 0,08284794 ! superoxide anion generation GO:0042554 18 14 0,000 0,05006897 0,08278838 ! neuron maturation GO:0042551 21 14 0,000 0,05006897 0,0827289 ! regulation of S phase GO:0033261 18 14 0,000 0,05006897 0,08266952 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,05006897 0,08261021 ! myotube differentiation GO:0014902 21 14 0,000 0,05006897 0,08255099 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,05006897 0,08249186 ! inositol metabolic process GO:0006020 20 14 0,000 0,05006897 0,08243281 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,05006897 0,08237384 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,05006897 0,08231496 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,05006897 0,08225617 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,05006897 0,08219746 ! gene silencing by RNA GO:0031047 20 14 0,000 0,05006897 0,08213883 ! response to cAMP GO:0051591 19 14 0,000 0,05006897 0,08208028 ! limbic system development GO:0021761 25 14 0,000 0,05006897 0,08202182 ! startle response GO:0001964 21 14 0,000 0,05006897 0,08196344 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,05006897 0,08190515 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,05006897 0,08184693 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,05006897 0,0817888 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,05006897 0,08173076 ! glycine metabolic process GO:0006544 22 14 0,000 0,05006897 0,08167279 ! pituitary gland development GO:0021983 23 14 0,000 0,05006897 0,08161491 ! cellular response to starvation GO:0009267 21 14 0,000 0,05006897 0,08155711 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,05006897 0,08149939 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,05006897 0,08144175 ! regulation of heart rate GO:0002027 23 14 0,000 0,05006897 0,08138419 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,05006897 0,08132672 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,05006897 0,08126933 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,05006897 0,08121201 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,05006897 0,08115478 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,05006897 0,08109763 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,05006897 0,08104056 ! intermediate filament-based process GO:0045103 24 14 0,000 0,05006897 0,08098357 ! axon cargo transport GO:0008088 27 14 0,000 0,05006897 0,08092666 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,05006897 0,08086983 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,05006897 0,08081308 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,05006897 0,08075641 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,05006897 0,08069981 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05006897 0,0806433 ! mRNA splice site selection GO:0006376 26 14 0,000 0,05006897 0,08058687 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,05006897 0,08053051 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,05006897 0,08047424 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,05006897 0,08041804 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,05006897 0,08036192 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,05006897 0,08030588 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,05006897 0,08024992 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,05006897 0,08019404 ! muscle maintenance GO:0046716 19 14 0,000 0,05006897 0,08013823 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,05006897 0,0800825 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,05006897 0,08002685 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,05006897 0,07997127 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,05006897 0,07991578 ! cell killing GO:0001906 20 14 0,000 0,05006897 0,07986036 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,05006897 0,07980501 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,05006897 0,07974975 ! cilium assembly GO:0042384 20 14 0,000 0,05006897 0,07969456 ! peptide hormone secretion GO:0030072 23 14 0,000 0,05006897 0,07963944 ! protein import GO:0017038 156 99 1,000 0,05101617 0,08108997 ! regulation of translation GO:0006417 151 100 1,000 0,05193736 0,08249718 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,05193736 0,08244025 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,05193736 0,08238339 ! protein localization in organelle GO:0033365 161 100 1,000 0,05193736 0,08232662 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,05354937 0,08482338 ! positive regulation of cell size GO:0045793 20 15 0,000 0,05354937 0,084765 ! metencephalon development GO:0022037 19 15 0,000 0,05354937 0,08470671 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05354937 0,08464849 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,05354937 0,08459035 ! skin development GO:0043588 25 15 0,000 0,05354937 0,08453229 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,05354937 0,08447431 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,05354937 0,08441641 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,05354937 0,0843586 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05354937 0,08430085 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05354937 0,08424319 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05354937 0,08418561 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,05354937 0,08412811 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05354937 0,08407068 ! adult walking behavior GO:0007628 25 15 0,000 0,05354937 0,08401333 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05354937 0,08395607 ! myoblast differentiation GO:0045445 27 15 0,000 0,05354937 0,08389888 ! centrosome cycle GO:0007098 16 15 0,000 0,05354937 0,08384176 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05354937 0,08378473 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,05354937 0,08372777 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,05354937 0,08367089 ! cerebral cortex development GO:0021987 29 15 0,000 0,05354937 0,08361409 ! response to osmotic stress GO:0006970 22 15 0,000 0,05354937 0,08355736 ! vesicle coating GO:0006901 25 15 0,000 0,05354937 0,08350071 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,05354937 0,08344414 ! DNA integration GO:0015074 22 15 0,000 0,05354937 0,08338764 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,05354937 0,08333122 ! peptide secretion GO:0002790 27 15 0,000 0,05354937 0,08327488 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05354937 0,08321861 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,05354937 0,08316242 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,05354937 0,08310631 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05354937 0,08305027 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,05354937 0,08299431 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05354937 0,08293842 ! biomineral formation GO:0031214 18 15 0,000 0,05354937 0,0828826 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05354937 0,08282687 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,05354937 0,0827712 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05354937 0,08271561 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05354937 0,0826601 ! organic cation transport GO:0015695 19 15 0,000 0,05354937 0,08260466 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05354937 0,0825493 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05354937 0,082494 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,05354937 0,08243879 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,05354937 0,08238364 ! defense response to virus GO:0051607 27 15 0,000 0,05354937 0,08232858 ! peptide hormone processing GO:0016486 19 15 0,000 0,05354937 0,08227358 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,05354937 0,08221866 ! protein secretion GO:0009306 27 16 0,000 0,05701721 0,08748472 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,05701721 0,08742639 ! hormone secretion GO:0046879 25 16 0,000 0,05701721 0,08736815 ! bone remodeling GO:0046849 24 16 0,000 0,05701721 0,08730998 ! endothelial cell migration GO:0043542 22 16 0,000 0,05701721 0,08725189 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,05701721 0,08719388 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05701721 0,08713594 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,05701721 0,08707808 ! glial cell development GO:0021782 24 16 0,000 0,05701721 0,0870203 ! patterning of blood vessels GO:0001569 24 16 0,000 0,05701721 0,08696259 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,05701721 0,08690496 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,05701721 0,08684741 ! protein polyubiquitination GO:0000209 26 16 0,000 0,05701721 0,08678993 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,05701721 0,08673253 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,05701721 0,08667521 GO:0030968|endoplasmic reticulum unfolded protein response, ! fructose metabolic process GO:0006000 20 16 0,000 0,05701721 0,08661796 ! regulation of protein binding GO:0043393 27 16 0,000 0,05701721 0,08656079 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,05701721 0,08650369 ! protein export from nucleus GO:0006611 24 16 0,000 0,05701721 0,08644667 ! negative regulation of immune response GO:0050777 28 16 0,000 0,05701721 0,08638972 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,05701721 0,08633284 ! DNA replication initiation GO:0006270 25 16 0,000 0,05701721 0,08627605 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,05701721 0,08621932 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,05701721 0,08616268 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,05701721 0,0861061 ! diencephalon development GO:0021536 25 16 0,000 0,05701721 0,0860496 ! neural crest cell migration GO:0001755 24 16 0,000 0,05701721 0,08599317 ! G1 phase GO:0051318 27 16 0,000 0,05701721 0,08593682 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,05701721 0,08588054 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,05701721 0,08582434 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,05701721 0,08576821 ! steroid catabolic process GO:0006706 22 16 0,000 0,05701721 0,08571215 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,05701721 0,08565617 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,05701721 0,08560026 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,05701721 0,08554442 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,05701721 0,08548865 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,05701721 0,08543296 ! sperm-egg recognition GO:0035036 16 16 0,000 0,05701721 0,08537734 GO:0007339|binding of sperm to zona pellucida, ! nerve development GO:0021675 18 16 0,000 0,05701721 0,08532179 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,05701721 0,08526631 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,05701721 0,08521091 ! negative regulation of translation GO:0017148 22 16 0,000 0,05701721 0,08515558 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,06047255 0,09025754 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,06047255 0,090199 ! negative regulation of defense response GO:0031348 19 17 0,000 0,06047255 0,09014055 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,06047255 0,09008217 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,06047255 0,09002386 ! glycerol metabolic process GO:0006071 20 17 0,000 0,06047255 0,08996563 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,06047255 0,08990748 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,06047255 0,0898494 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,06047255 0,08979139 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,06047255 0,08973346 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,06047255 0,08967561 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,06047255 0,08961782 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,06047255 0,08956012 ! memory GO:0007613 25 17 0,000 0,06047255 0,08950249 ! keratinization GO:0031424 17 17 0,000 0,06047255 0,08944493 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,06047255 0,08938744 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,06047255 0,08933003 ! retinoid metabolic process GO:0001523 22 17 0,000 0,06047255 0,0892727 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,06047255 0,08921544 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,06047255 0,08915825 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,06047255 0,08910113 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,06047255 0,08904409 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,06047255 0,08898712 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,06047255 0,08893022 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,06047255 0,0888734 ! membrane budding GO:0006900 29 17 0,000 0,06047255 0,08881664 ! heme metabolic process GO:0042168 27 17 0,000 0,06047255 0,08875996 ! actin filament bundle formation GO:0051017 26 17 0,000 0,06047255 0,08870336 ! neuromuscular junction development GO:0007528 23 17 0,000 0,06047255 0,08864682 ! body fluid secretion GO:0007589 27 17 0,000 0,06047255 0,08859036 ! stem cell differentiation GO:0048863 36 17 0,000 0,06047255 0,08853397 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,06047255 0,08847765 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,06047255 0,0884214 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,06047255 0,08836523 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,06047255 0,08830912 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,06047255 0,08825309 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,06047255 0,08819712 ! synaptogenesis GO:0007416 24 17 0,000 0,06047255 0,08814123 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,06047255 0,08808541 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,06047255 0,08802966 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,06047255 0,08797398 ! cell-cell junction organization GO:0045216 25 17 0,000 0,06047255 0,08791837 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,06047255 0,08786283 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,06047255 0,08780736 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,06047255 0,08775196 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,06047255 0,08769664 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,06047255 0,08764138 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,06391542 0,09257271 ! positive regulation of translation GO:0045727 28 18 0,000 0,06391542 0,09251446 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,06391542 0,09245627 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,06391542 0,09239816 ! cAMP metabolic process GO:0046058 33 18 0,000 0,06391542 0,09234012 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,06391542 0,09228215 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,06391542 0,09222426 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,06391542 0,09216644 ! axis specification GO:0009798 26 18 0,000 0,06391542 0,09210869 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,06391542 0,09205101 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,06391542 0,09199341 ! pancreas development GO:0031016 26 18 0,000 0,06391542 0,09193588 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,06391542 0,09187842 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,06391542 0,09182103 ! glutamine metabolic process GO:0006541 23 18 0,000 0,06391542 0,09176371 ! response to retinoic acid GO:0032526 25 18 0,000 0,06391542 0,09170647 ! pigmentation during development GO:0048066 31 18 0,000 0,06391542 0,0916493 ! central nervous system neuron development GO:0021954 30 18 0,000 0,06391542 0,09159219 ! fucose metabolic process GO:0006004 26 18 0,000 0,06391542 0,09153516 ! response to fungus GO:0009620 19 18 0,000 0,06391542 0,0914782 ! peptide cross-linking GO:0018149 31 18 0,000 0,06391542 0,09142131 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,06391542 0,09136449 ! heart process GO:0003015 27 18 0,000 0,06391542 0,09130775 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,06391542 0,09125107 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,06391542 0,09119446 ! visual learning GO:0008542 35 18 0,000 0,06391542 0,09113792 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,06391542 0,09108146 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,06391542 0,09102506 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,06391542 0,09096873 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,06391542 0,09091247 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,06391542 0,09085629 ! vitamin transport GO:0051180 24 18 0,000 0,06391542 0,09080017 ! hormone transport GO:0009914 27 18 0,000 0,06391542 0,09074412 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,06391542 0,09068814 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,06391542 0,09063223 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,06391542 0,09057638 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,06391542 0,09052061 ! cell-cell recognition GO:0009988 20 18 0,000 0,06391542 0,0904649 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,06391542 0,09040927 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,06391542 0,0903537 ! regulation of glucose import GO:0046324 21 18 0,000 0,06391542 0,0902982 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,06391542 0,09024277 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,06391542 0,0901874 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,06391542 0,09013211 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,06391542 0,09007688 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,06734587 0,09485334 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,06734587 0,09479529 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,06734587 0,09473731 ! positive regulation of ossification GO:0045778 30 19 0,000 0,06734587 0,09467941 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,06734587 0,09462157 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,06734587 0,0945638 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,06734587 0,09450611 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,06734587 0,09444848 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,06734587 0,09439093 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,06734587 0,09433344 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,06734587 0,09427602 ! response to alkaloid GO:0043279 32 19 0,000 0,06734587 0,09421868 ! sensory perception of taste GO:0050909 23 19 0,000 0,06734587 0,0941614 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,06734587 0,0941042 ! smooth muscle contraction GO:0006939 36 19 0,000 0,06734587 0,09404706 ! peroxisome organization GO:0007031 29 19 0,000 0,06734587 0,09398999 ! digestive system process GO:0022600 30 19 0,000 0,06734587 0,093933 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,06734587 0,09387607 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,06734587 0,09381921 ! response to vitamin A GO:0033189 26 19 0,000 0,06734587 0,09376241 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,06734587 0,09370569 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,06734587 0,09364904 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,06734587 0,09359245 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,06734587 0,09353594 ! response to starvation GO:0042594 30 19 0,000 0,06734587 0,09347949 ! sex determination GO:0007530 29 19 0,000 0,06734587 0,09342311 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,06734587 0,09336679 ! plasma membrane fusion GO:0045026 23 19 0,000 0,06734587 0,09331055 ! cytolysis GO:0019835 20 19 0,000 0,06734587 0,09325437 ! renal system process GO:0003014 35 19 0,000 0,06734587 0,09319826 ! vasodilation GO:0042311 33 19 0,000 0,06734587 0,09314222 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,06734587 0,09308624 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,06734587 0,09303034 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,06734587 0,0929745 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,06734587 0,09291872 ! sarcomere organization GO:0045214 23 19 0,000 0,06734587 0,09286302 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,06734587 0,09280738 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,06734587 0,0927518 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,06734587 0,0926963 GO:0043450|alkene biosynthetic process, ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,06734587 0,09264085 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,07076395 0,09728457 ! iron ion transport GO:0006826 37 20 0,000 0,07076395 0,09722645 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,07076395 0,09716841 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,07076395 0,09711043 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,07076395 0,09705252 ! response to vitamin GO:0033273 29 20 0,000 0,07076395 0,09699469 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,07076395 0,09693692 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,07076395 0,09687922 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,07076395 0,09682158 ! spinal cord development GO:0021510 31 20 0,000 0,07076395 0,09676402 ! response to ethanol GO:0045471 37 20 0,000 0,07076395 0,09670653 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,07076395 0,0966491 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,07076395 0,09659174 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,07076395 0,09653445 ! chromosome condensation GO:0030261 31 20 0,000 0,07076395 0,09647723 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,07076395 0,09642007 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,07076395 0,09636299 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,07076395 0,09630597 ! pallium development GO:0021543 38 20 0,000 0,07076395 0,09624901 ! DNA modification GO:0006304 28 20 0,000 0,07076395 0,09619213 ! collagen fibril organization GO:0030199 45 20 0,000 0,07076395 0,09613531 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,07076395 0,09607856 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,07076395 0,09602188 ! collagen catabolic process GO:0030574 25 20 0,000 0,07076395 0,09596526 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,07076395 0,09590871 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,07076395 0,09585223 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,07076395 0,09579581 ! alditol metabolic process GO:0019400 24 20 0,000 0,07076395 0,09573946 ! actin filament-based movement GO:0030048 34 20 0,000 0,07076395 0,09568318 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,07416969 0,10022932 ! regulation of cell killing GO:0031341 34 21 0,000 0,07416969 0,10017046 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,07416969 0,10011168 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,07416969 0,10005296 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,07416969 0,09999431 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,07416969 0,09993573 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,07416969 0,09987722 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,07416969 0,09981878 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,07416969 0,09976041 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,07416969 0,0997021 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,07416969 0,09964386 ! phototransduction GO:0007602 25 21 0,000 0,07416969 0,0995857 ! dendrite development GO:0016358 35 21 0,000 0,07416969 0,09952759 ! visual behavior GO:0007632 39 21 0,000 0,07416969 0,09946956 ! ovarian follicle development GO:0001541 30 21 0,000 0,07416969 0,09941159 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,07416969 0,0993537 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,07416969 0,09929587 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,07416969 0,0992381 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,07416969 0,0991804 ! cell aging GO:0007569 32 21 0,000 0,07416969 0,09912278 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,07416969 0,09906521 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,07416969 0,09900772 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,07416969 0,09895029 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,07416969 0,09889293 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,07416969 0,09883563 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,07416969 0,0987784 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,07416969 0,09872124 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,07416969 0,09866414 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,07416969 0,09860711 ! fatty acid transport GO:0015908 30 21 0,000 0,07416969 0,09855014 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,07416969 0,09849324 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,07416969 0,09843641 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,07416969 0,09837964 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,07416969 0,09832294 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,07416969 0,0982663 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,07416969 0,09820973 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,07416969 0,09815322 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,07416969 0,09809678 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,07416969 0,0980404 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,07416969 0,09798409 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,07416969 0,09792784 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,07756315 0,10234954 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,07756315 0,10229085 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,07756315 0,10223223 ! viral genome replication GO:0019079 29 22 0,000 0,07756315 0,10217368 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,07756315 0,10211519 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,07756315 0,10205678 ! leukocyte adhesion GO:0007159 38 22 0,000 0,07756315 0,10199843 ! molting cycle process GO:0022404 40 22 0,000 0,07756315 0,10194014 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,07756315 0,10188192 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,07756315 0,10182377 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,07756315 0,10176568 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,07756315 0,10170767 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,07756315 0,10164971 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,07756315 0,10159183 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,07756315 0,101534 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,07756315 0,10147625 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 37 22 0,000 0,07756315 0,10141856 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,07756315 0,10136093 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,07756315 0,10130338 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,07756315 0,10124588 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,07756315 0,10118845 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,07756315 0,10113109 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,07756315 0,10107379 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,07756315 0,10101656 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,07756315 0,10095939 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,07756315 0,10090229 ! blastocyst development GO:0001824 37 22 0,000 0,07756315 0,10084525 ! neural tube closure GO:0001843 33 22 0,000 0,07756315 0,10078827 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,07756315 0,10073136 ! protein tetramerization GO:0051262 39 22 0,000 0,07756315 0,10067452 ! neuron fate commitment GO:0048663 32 23 0,000 0,08094436 0,10500397 ! embryonic pattern specification GO:0009880 31 23 0,000 0,08094436 0,10494478 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,08094436 0,10488565 ! myelination GO:0042552 35 23 0,000 0,08094436 0,10482659 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,08094436 0,1047676 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,08094436 0,10470868 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,08094436 0,10464982 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,08094436 0,10459103 ! vesicle targeting GO:0006903 32 23 0,000 0,08094436 0,1045323 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,08094436 0,10447364 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,08094436 0,10441505 ! osteoblast differentiation GO:0001649 40 23 0,000 0,08094436 0,10435652 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,08094436 0,10429806 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,08094436 0,10423966 ! interaction with host GO:0051701 37 23 0,000 0,08094436 0,10418133 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,08094436 0,10412306 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,08094436 0,10406486 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,08094436 0,10400672 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,08094436 0,10394865 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,08094436 0,10389064 ! glycolipid metabolic process GO:0006664 36 23 0,000 0,08094436 0,1038327 ! cell fate determination GO:0001709 45 23 0,000 0,08094436 0,10377482 ! pentose metabolic process GO:0019321 31 23 0,000 0,08094436 0,10371701 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,08094436 0,10365926 ! spermatid development GO:0007286 33 23 0,000 0,08094436 0,10360158 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,08094436 0,10354396 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,08094436 0,1034864 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,08094436 0,10342891 ! telomere organization GO:0032200 32 23 0,000 0,08094436 0,10337148 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,08094436 0,10331411 ! regulation of amine transport GO:0051952 38 23 0,000 0,08094436 0,10325681 ! liver development GO:0001889 40 23 0,000 0,08094436 0,10319957 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,08431337 0,10743532 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,08431337 0,10737583 ! initiation of viral infection GO:0019059 42 24 0,000 0,08431337 0,10731641 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,08431337 0,10725706 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,08431337 0,10719777 ! superoxide metabolic process GO:0006801 32 24 0,000 0,08431337 0,10713854 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,08431337 0,10707938 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,08431337 0,10702029 ! sperm motility GO:0030317 27 24 0,000 0,08431337 0,10696126 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,08431337 0,10690229 ! vacuole organization GO:0007033 39 24 0,000 0,08431337 0,10684339 ! neural crest cell development GO:0014032 39 24 0,000 0,08431337 0,10678456 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,08431337 0,10672579 ! primary neural tube formation GO:0014020 35 24 0,000 0,08431337 0,10666708 ! negative regulation of cell development GO:0010721 56 24 0,000 0,08431337 0,10660844 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,08431337 0,10654987 ! base-excision repair GO:0006284 31 24 0,000 0,08431337 0,10649136 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,08431337 0,10643291 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,08431337 0,10637452 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,08431337 0,1063162 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,08431337 0,10625795 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,08767023 0,110428 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,08767023 0,11036755 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,08767023 0,11030718 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,08767023 0,11024687 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,08767023 0,11018662 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,08767023 0,11012644 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,08767023 0,11006633 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 43 25 0,000 0,08767023 0,11000628 ! male gonad development GO:0008584 33 25 0,000 0,08767023 0,1099463 ! iron ion homeostasis GO:0055072 39 25 0,000 0,08767023 0,10988639 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,08767023 0,10982654 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,08767023 0,10976675 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,08767023 0,10970703 ! phospholipid transport GO:0015914 35 25 0,000 0,08767023 0,10964737 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,08767023 0,10958778 ! detection of light stimulus GO:0009583 30 25 0,000 0,08767023 0,10952826 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,08767023 0,10946879 ! leukocyte proliferation GO:0070661 39 25 0,000 0,08767023 0,1094094 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,08767023 0,10935007 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,09101496 0,11346039 ! translational initiation GO:0006413 43 26 0,000 0,09101496 0,11339893 ! regulation of pH GO:0006885 36 26 0,000 0,09101496 0,11333753 ! circadian rhythm GO:0007623 42 26 0,000 0,09101496 0,1132762 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,09101496 0,11321494 ! post-embryonic development GO:0009791 42 26 0,000 0,09101496 0,11315374 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,09101496 0,11309261 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,09101496 0,11303154 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,09101496 0,11297054 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,09101496 0,11290961 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,09101496 0,11284874 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,09101496 0,11278794 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,09434763 0,1168549 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,09434763 0,11679201 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,09434763 0,11672918 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,09434763 0,11666643 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,09434763 0,11660374 ! catechol metabolic process GO:0009712 43 27 0,000 0,09434763 0,11654111 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,09434763 0,11647856 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,09434763 0,11641607 ! myofibril assembly GO:0030239 36 27 0,000 0,09434763 0,11635365 GO:0055002|striated muscle cell development, ! response to ionizing radiation GO:0010212 47 27 0,000 0,09434763 0,11629129 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,09434763 0,11622901 ! natural killer cell activation GO:0030101 35 27 0,000 0,09434763 0,11616679 ! lipid oxidation GO:0034440 38 27 0,000 0,09434763 0,11610463 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,09434763 0,11604254 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,09434763 0,11598052 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,09434763 0,11591857 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,09434763 0,11585668 ! gene silencing GO:0016458 41 27 0,000 0,09434763 0,11579485 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,09766827 0,11980641 ! phenol metabolic process GO:0018958 44 28 0,000 0,09766827 0,11974255 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,09766827 0,11967876 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,09766827 0,11961503 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,09766827 0,11955137 ! cell junction assembly GO:0034329 56 28 0,000 0,09766827 0,11948778 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,09766827 0,11942426 ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,09766827 0,1193608 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,09766827 0,11929741 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,09766827 0,11923409 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,09766827 0,11917083 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,09766827 0,11910765 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,09766827 0,11904453 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,09766827 0,11898147 ! mesoderm formation GO:0001707 46 28 0,000 0,09766827 0,11891849 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,09766827 0,11885557 ! ensheathment of neurons GO:0007272 43 28 0,000 0,09766827 0,11879271 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,09766827 0,11872993 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,09766827 0,11866721 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,09766827 0,11860455 ! neural tube formation GO:0001841 41 28 0,000 0,09766827 0,11854197 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,09766827 0,11847944 ! placenta development GO:0001890 37 28 0,000 0,09766827 0,11841699 ! regulation of B cell activation GO:0050864 42 28 0,000 0,09766827 0,1183546 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,10097692 0,12229959 ! regulation of innate immune response GO:0045088 38 29 0,000 0,10097692 0,12223522 ! ovulation cycle process GO:0022602 41 29 0,000 0,10097692 0,12217092 ! protein targeting to membrane GO:0006612 53 29 0,000 0,10097692 0,12210669 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,10097692 0,12204253 ! muscle cell development GO:0055001 38 29 0,000 0,10097692 0,12197843 ! formation of primary germ layer GO:0001704 48 29 0,000 0,10097692 0,1219144 ! telencephalon development GO:0021537 52 29 0,000 0,10097692 0,12185043 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,10097692 0,12178654 ! eye morphogenesis GO:0048592 51 29 0,000 0,10097692 0,12172271 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,10097692 0,12165894 ! tissue homeostasis GO:0001894 42 29 0,000 0,10097692 0,12159525 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,10427363 0,1254994 ! collagen metabolic process GO:0032963 40 30 0,000 0,10427363 0,12543376 ! organic anion transport GO:0015711 51 30 0,000 0,10427363 0,1253682 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,10427363 0,1253027 ! spliceosome assembly GO:0000245 49 30 0,000 0,10427363 0,12523726 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,10427363 0,1251719 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,10427363 0,1251066 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,10427363 0,12504138 ! ceramide metabolic process GO:0006672 43 30 0,000 0,10427363 0,12497622 ! ovulation cycle GO:0042698 43 30 0,000 0,10427363 0,12491112 ! hindbrain development GO:0030902 45 30 0,000 0,10427363 0,1248461 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,10427363 0,12478114 ! adult locomotory behavior GO:0008344 47 30 0,000 0,10427363 0,12471626 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,10427363 0,12465143 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,10427363 0,12458668 ! response to heat GO:0009408 41 30 0,000 0,10427363 0,12452199 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,10427363 0,12445737 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,10427363 0,12439282 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,10755844 0,1282449 ! glial cell differentiation GO:0010001 55 31 0,000 0,10755844 0,12817846 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,10755844 0,12811208 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,10755844 0,12804577 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,10755844 0,12797952 ! odontogenesis GO:0042476 50 31 0,000 0,10755844 0,12791335 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,10755844 0,12784725 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,10755844 0,12778121 ! metanephros development GO:0001656 58 31 0,000 0,10755844 0,12771524 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,10755844 0,12764934 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,10755844 0,12758351 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,10755844 0,12751774 ! cell fate specification GO:0001708 37 31 0,000 0,10755844 0,12745205 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,10755844 0,12738642 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,10755844 0,12732085 ! RNA modification GO:0009451 40 31 0,000 0,10755844 0,12725536 ! regulation of muscle development GO:0048634 48 32 0,000 0,11083139 0,13106026 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,11083139 0,13099291 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,11083139 0,13092563 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,11083139 0,13085842 ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,11083139 0,13079128 ! peripheral nervous system development GO:0007422 53 32 0,000 0,11083139 0,13072421 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,11083139 0,1306572 ! cytokine production GO:0001816 44 32 0,000 0,11083139 0,13059027 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,11083139 0,1305234 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,11083139 0,1304566 ! vesicle localization GO:0051648 47 32 0,000 0,11083139 0,13038987 ! RNA export from nucleus GO:0006405 44 33 0,000 0,11409253 0,13415788 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,11409253 0,13408933 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,11409253 0,13402084 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,11409253 0,13395243 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,11409253 0,13388409 ! sister chromatid segregation GO:0000819 46 33 0,000 0,11409253 0,13381582 ! ear morphogenesis GO:0042471 42 33 0,000 0,11409253 0,13374761 ! actomyosin structure organization GO:0031032 43 33 0,000 0,11409253 0,13367948 ! cell junction organization GO:0034330 63 33 0,000 0,11409253 0,13361141 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,11409253 0,13354342 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,11409253 0,13347549 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,11409253 0,13340763 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,11409253 0,13333984 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,11409253 0,13327213 ! female gonad development GO:0008585 49 33 0,000 0,11409253 0,13320447 ! positive regulation of cell development GO:0010720 54 33 0,000 0,11409253 0,13313689 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,11409253 0,13306938 ! regulation of proteolysis GO:0030162 50 33 0,000 0,11409253 0,13300193 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,11409253 0,13293456 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,11409253 0,13286725 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,11409253 0,13280001 ! cytokinesis GO:0000910 52 33 0,000 0,11409253 0,13273283 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,11734189 0,13644406 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,11734189 0,13637511 ! feeding behavior GO:0007631 45 34 0,000 0,11734189 0,13630623 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,11734189 0,13623743 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,11734189 0,13616869 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,11734189 0,13610002 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,11734189 0,13603142 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,11734189 0,13596289 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,11734189 0,13589443 ! polyol metabolic process GO:0019751 44 34 0,000 0,11734189 0,13582604 ! aerobic respiration GO:0009060 47 34 0,000 0,11734189 0,13575772 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,11734189 0,13568946 ! embryonic organ development GO:0048568 45 34 0,000 0,11734189 0,13562128 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,11734189 0,13555316 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,12057951 0,13922334 ! Notch signaling pathway GO:0007219 56 35 0,000 0,12057951 0,13915348 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,12057951 0,13908369 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,12057951 0,13901398 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,12057951 0,13894433 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,12057951 0,13887475 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,12057951 0,13880525 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,12057951 0,13873581 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,12057951 0,13866644 ! pigment metabolic process GO:0042440 61 35 0,000 0,12057951 0,13859714 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,12380545 0,14223403 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,12380545 0,14216302 ! neural tube development GO:0021915 50 36 0,000 0,12380545 0,14209208 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,12380545 0,14202122 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,12380545 0,14195042 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,12380545 0,14187969 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,12380545 0,14180903 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,12701974 0,14541832 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,12701974 0,14534597 ! learning GO:0007612 67 37 0,000 0,12701974 0,14527369 ! ion transmembrane transport GO:0034220 56 37 0,000 0,12701974 0,14520149 ! regulation of protein secretion GO:0050708 51 37 0,000 0,12701974 0,14512936 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,12701974 0,1450573 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,13022242 0,14864097 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,13022242 0,14856724 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,13022242 0,14849358 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,13022242 0,14842 ! phagocytosis GO:0006909 60 38 0,000 0,13022242 0,14834649 ! mesenchymal cell development GO:0014031 64 38 0,000 0,13022242 0,14827305 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,13022242 0,14819968 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,13341353 0,15175624 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,13341353 0,15168123 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,13341353 0,15160628 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,13341353 0,15153142 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,13341353 0,15145662 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,13341353 0,1513819 ! male sex differentiation GO:0046661 53 39 0,000 0,13341353 0,15130726 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,13341353 0,15123269 ! chromatin remodeling GO:0006338 68 39 0,000 0,13341353 0,15115819 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,13341353 0,15108376 ! JNK cascade GO:0007254 54 39 0,000 0,13341353 0,15100941 ! developmental growth GO:0048589 62 39 0,000 0,13341353 0,15093513 ! synapse organization GO:0050808 55 39 0,000 0,13341353 0,15086092 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,13659312 0,15438043 ! response to calcium ion GO:0051592 58 40 0,000 0,13659312 0,1543046 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,13659312 0,15422885 ! regulation of tube size GO:0035150 60 40 0,000 0,13659312 0,15415317 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,13659312 0,15407757 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,13659312 0,15400204 ! peptide metabolic process GO:0006518 56 40 0,000 0,13659312 0,15392659 ! inner ear development GO:0048839 57 40 0,000 0,13659312 0,15385121 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,13659312 0,1537759 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,13659312 0,15370067 ! B cell differentiation GO:0030183 62 40 0,000 0,13659312 0,15362551 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,13659312 0,15355042 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,13659312 0,15347541 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,13976122 0,1569584 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,13976122 0,1568818 ! glucose transport GO:0015758 52 41 0,000 0,13976122 0,15680527 ! striated muscle contraction GO:0006941 62 41 0,000 0,13976122 0,15672882 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,13976122 0,15665244 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,13976122 0,15657613 ! biopolymer methylation GO:0043414 62 41 0,000 0,13976122 0,1564999 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,13976122 0,15642375 ! mitochondrial transport GO:0006839 60 42 0,000 0,14291788 0,15987895 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,14291788 0,15980122 ! cellular component disassembly GO:0022411 64 42 0,000 0,14291788 0,15972358 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,14291788 0,159646 ! hexose transport GO:0008645 54 42 0,000 0,14291788 0,1595685 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,14291788 0,15949108 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,14291788 0,15941373 ! excretion GO:0007588 63 42 0,000 0,14291788 0,15933646 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,14291788 0,15925926 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,14291788 0,15918214 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,14291788 0,15910509 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,14606313 0,16252792 ! leukocyte migration GO:0050900 60 43 0,000 0,14606313 0,16244933 ! neuromuscular process GO:0050905 79 43 0,000 0,14606313 0,16237081 ! activation of caspase activity GO:0006919 65 43 0,000 0,14606313 0,16229237 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,14606313 0,16221401 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,14606313 0,16213572 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,14606313 0,1620575 ! methylation GO:0032259 64 43 0,000 0,14606313 0,16197937 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,14919703 0,16537502 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,14919703 0,16529536 ! glycolysis GO:0006096 53 44 0,000 0,14919703 0,16521577 ! regulation of action potential GO:0001508 71 44 0,000 0,14919703 0,16513627 ! regulation of ion transport GO:0043269 57 44 0,000 0,14919703 0,16505683 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,14919703 0,16497748 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,14919703 0,1648982 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,14919703 0,164819 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,14919703 0,16473987 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,14919703 0,16466083 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,14919703 0,16458185 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,1523196 0,16794586 ! cell maturation GO:0048469 60 45 0,000 0,1523196 0,16786539 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,15543089 0,17121218 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,15543089 0,17113022 ! cell redox homeostasis GO:0045454 63 46 0,000 0,15543089 0,17104834 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,15543089 0,17096654 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,15853093 0,17429309 ! viral infectious cycle GO:0019058 71 47 0,000 0,15853093 0,17420982 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,15853093 0,17412662 ! endocrine system development GO:0035270 83 47 0,000 0,15853093 0,17404351 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,15853093 0,17396047 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,15853093 0,17387751 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,15853093 0,17379464 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,15853093 0,17371184 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,15853093 0,17362912 ! chloride transport GO:0006821 67 48 0,000 0,16161978 0,17692789 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,16161978 0,17684372 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,16161978 0,17675962 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,16161978 0,17667561 ! gastrulation GO:0007369 73 48 0,000 0,16161978 0,17659168 ! heart morphogenesis GO:0003007 65 48 0,000 0,16161978 0,17650783 ! regulation of DNA replication GO:0006275 75 48 0,000 0,16161978 0,17642406 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,16161978 0,17634037 ! regulation of endocytosis GO:0030100 63 48 0,000 0,16161978 0,17625675 ! nuclear export GO:0051168 69 48 0,000 0,16161978 0,17617322 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,16161978 0,17608976 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,16469746 0,17935803 ! sensory perception of smell GO:0007608 61 49 0,000 0,16469746 0,17927315 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,16469746 0,17918835 ! RNA elongation GO:0006354 62 49 0,000 0,16469746 0,17910362 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,16469746 0,17901898 ! germ cell development GO:0007281 68 49 0,000 0,16469746 0,17893442 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,16469746 0,17884994 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,16469746 0,17876553 ! cartilage development GO:0051216 70 49 0,000 0,16469746 0,17868121 ! regulation of actin filament length GO:0030832 72 50 0,000 0,16776402 0,18192233 ! ear development GO:0043583 72 50 0,000 0,16776402 0,18183659 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,16776402 0,18175094 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,16776402 0,18166537 ! positive regulation of growth GO:0045927 67 50 0,000 0,16776402 0,18157988 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,16776402 0,18149447 ! proton transport GO:0015992 75 50 0,000 0,16776402 0,18140915 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,16776402 0,1813239 ! positive regulation of secretion GO:0051047 71 51 0,000 0,1708195 0,18453962 ! hydrogen transport GO:0006818 77 51 0,000 0,1708195 0,18445298 ! muscle fiber development GO:0048747 74 51 0,000 0,1708195 0,18436643 ! adult behavior GO:0030534 80 51 0,000 0,1708195 0,18427995 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,1708195 0,18419356 ! transition metal ion transport GO:0000041 74 52 0,000 0,17386394 0,1873885 ! regulation of cellular component size GO:0032535 74 52 0,000 0,17386394 0,18730073 ! aging GO:0007568 79 52 0,000 0,17386394 0,18721304 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,17386394 0,18712544 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,17386394 0,18703791 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,17689737 0,19021222 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,17689737 0,19012334 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,17689737 0,19003454 ! kidney development GO:0001822 90 53 0,000 0,17689737 0,18994582 ! single fertilization GO:0007338 59 53 0,000 0,17689737 0,18985718 ! cell projection assembly GO:0030031 76 53 0,000 0,17689737 0,18976863 ! amino acid transport GO:0006865 84 54 0,000 0,17991983 0,19292104 ! glucose catabolic process GO:0006007 66 54 0,000 0,17991983 0,19283114 ! DNA catabolic process GO:0006308 67 54 0,000 0,17991983 0,19274132 ! detection of external stimulus GO:0009581 66 54 0,000 0,17991983 0,19265159 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,17991983 0,19256195 ! exocytosis GO:0006887 74 55 0,000 0,18293138 0,19569403 ! mesoderm development GO:0007498 76 55 0,000 0,18293138 0,19560305 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,18293138 0,19551216 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,18593203 0,19862688 ! carbohydrate transport GO:0008643 74 57 0,000 0,18892183 0,20172712 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,18892183 0,20163351 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,18892183 0,20153999 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,18892183 0,20144656 ! camera-type eye development GO:0043010 88 57 0,000 0,18892183 0,20135321 ! secondary metabolic process GO:0019748 84 57 0,000 0,18892183 0,20125994 ! developmental maturation GO:0021700 75 57 0,000 0,18892183 0,20116677 ! gonad development GO:0008406 79 57 0,000 0,18892183 0,20107368 ! viral reproductive process GO:0022415 87 58 0,000 0,19190083 0,20414982 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,19190083 0,20405544 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,19190083 0,20396114 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,19486906 0,20702024 ! activation of MAPK activity GO:0000187 84 59 0,000 0,19486906 0,20692467 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,19486906 0,20682918 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,19782655 0,20987134 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,19782655 0,20977458 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,19782655 0,20967791 ! regulation of heart contraction GO:0008016 91 60 0,000 0,19782655 0,20958133 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,19782655 0,20948483 ! fertilization GO:0009566 68 60 0,000 0,19782655 0,20938843 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,20077334 0,2124097 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,20077334 0,21231204 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,20077334 0,21221447 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,20077334 0,21211699 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,20077334 0,2120196 ! extracellular matrix organization GO:0030198 103 61 0,000 0,20077334 0,2119223 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,20077334 0,21182509 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,20077334 0,21172797 ! amine catabolic process GO:0009310 90 62 0,000 0,20370948 0,21472585 ! neurotransmitter transport GO:0006836 81 62 0,000 0,20370948 0,21462749 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,20370948 0,21452922 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,20370948 0,21443104 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,20370948 0,21433294 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,20663501 0,21731162 ! viral reproduction GO:0016032 92 63 0,000 0,20663501 0,2172123 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,20954995 0,22017582 ! negative regulation of cell size GO:0045792 108 64 0,000 0,20954995 0,22007529 ! appendage morphogenesis GO:0035107 93 64 0,000 0,20954995 0,21997484 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,20954995 0,21987449 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,20954995 0,21977423 ! hexose catabolic process GO:0019320 82 64 0,000 0,20954995 0,21967406 ! regulation of caspase activity GO:0043281 97 65 0,000 0,21245435 0,22261731 ! appendage development GO:0048736 94 65 0,000 0,21245435 0,22251594 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,21245435 0,22241465 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,21245435 0,22231346 ! defense response to bacterium GO:0042742 73 65 0,000 0,21245435 0,22221237 ! activation of immune response GO:0002253 83 65 0,000 0,21245435 0,22211136 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,21534824 0,22503451 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,21534824 0,22493231 ! antigen processing and presentation GO:0019882 96 66 0,000 0,21534824 0,22483021 ! axon guidance GO:0007411 99 66 0,000 0,21534824 0,2247282 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,21534824 0,22462628 ! regulation of immune effector process GO:0002697 101 66 0,000 0,21534824 0,22452446 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,21823166 0,22742765 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,21823166 0,22732465 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,21823166 0,22722174 ! learning or memory GO:0007611 123 68 0,000 0,22110466 0,23010892 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,22110466 0,23000484 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,22110466 0,22990086 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,22110466 0,22979698 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,22110466 0,22969318 ! rhythmic process GO:0048511 105 68 0,000 0,22110466 0,22958948 ! inorganic anion transport GO:0015698 93 68 0,000 0,22110466 0,22948588 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,22396725 0,23235214 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,22396725 0,23224738 ! response to drug GO:0042493 108 69 0,000 0,22396725 0,23214272 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,22396725 0,23203815 ! response to metal ion GO:0010038 103 70 0,000 0,2268195 0,23488737 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,2268195 0,23478166 ! humoral immune response GO:0006959 86 70 0,000 0,2268195 0,23467604 ! eye development GO:0001654 111 70 0,000 0,2268195 0,23457052 ! amine transport GO:0015837 101 70 0,000 0,2268195 0,2344651 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,2268195 0,23435977 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,22966142 0,23718961 ! muscle cell differentiation GO:0042692 104 71 0,000 0,22966142 0,23708315 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,22966142 0,23697679 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,22966142 0,23687052 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,22966142 0,23676435 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,23249306 0,23957618 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,23249306 0,23946889 ! regulation of blood pressure GO:0008217 107 73 0,000 0,23531445 0,24226644 ! tube morphogenesis GO:0035239 118 73 0,000 0,23531445 0,24215805 ! mitochondrion organization GO:0007005 104 73 0,000 0,23531445 0,24204975 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,23531445 0,24194155 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,23531445 0,24183344 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,23812563 0,2446132 ! digestion GO:0007586 97 74 0,000 0,23812563 0,244504 ! response to inorganic substance GO:0010035 115 75 0,000 0,24092664 0,24726965 ! negative regulation of growth GO:0045926 123 75 0,000 0,24092664 0,24715936 ! response to nutrient GO:0007584 104 75 0,000 0,24092664 0,24704916 ! regulation of ligase activity GO:0051340 114 75 0,000 0,24092664 0,24693907 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,24092664 0,24682908 ! amine biosynthetic process GO:0009309 97 76 0,000 0,24371751 0,24957715 ! response to unfolded protein GO:0006986 99 76 0,000 0,24371751 0,24946608 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,24649828 0,2522002 ! protein ubiquitination GO:0016567 125 77 0,000 0,24649828 0,25208806 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,24649828 0,25197602 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,24649828 0,25186408 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,24649828 0,25175224 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,24926899 0,25446901 ! cellular respiration GO:0045333 107 79 0,000 0,25202966 0,25717312 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,25202966 0,25705908 ! T cell activation GO:0042110 134 79 0,000 0,25202966 0,25694513 ! chromatin assembly GO:0031497 102 80 0,000 0,25478034 0,25963438 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,25478034 0,25951939 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,25478034 0,25940451 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,25478034 0,25928973 ! forebrain development GO:0030900 131 80 0,000 0,25478034 0,25917505 ! mRNA transport GO:0051028 121 81 0,000 0,25752107 0,26184724 ! response to protein stimulus GO:0051789 111 81 0,000 0,25752107 0,26173153 ! regulation of neurological system process GO:0031644 122 81 0,000 0,25752107 0,26161592 ! vitamin metabolic process GO:0006766 103 81 0,000 0,25752107 0,26150042 ! detection of stimulus GO:0051606 108 82 0,000 0,26025187 0,26415679 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,26297278 0,26680079 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,26297278 0,26668315 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,26568384 0,26931372 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,26838508 0,27193202 ! rRNA metabolic process GO:0016072 107 85 0,000 0,26838508 0,27181228 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,26838508 0,27169265 ! cell cycle arrest GO:0007050 150 86 0,000 0,27107654 0,27429655 ! nucleosome organization GO:0034728 114 87 0,000 0,27375826 0,2768883 ! cellular defense response GO:0006968 102 87 0,000 0,27375826 0,27676659 ! female pregnancy GO:0007565 130 87 0,000 0,27375826 0,27664499 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,27375826 0,27652349 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,27643026 0,27909991 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,27643026 0,27897745 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,27643026 0,27885509 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,27643026 0,27873284 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,27909258 0,28129402 ! leukocyte differentiation GO:0002521 143 90 0,000 0,28174526 0,28384324 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,28174526 0,28371896 ! hormone metabolic process GO:0042445 121 90 0,000 0,28174526 0,2835948 ! RNA localization GO:0006403 135 91 0,000 0,28438834 0,28613 ! cell fate commitment GO:0045165 141 92 0,000 0,28702183 0,28865335 ! sulfur metabolic process GO:0006790 118 92 0,000 0,28702183 0,28852719 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,28964579 0,29103771 ! response to oxidative stress GO:0006979 141 94 0,000 0,29226024 0,29353649 ! carboxylic acid transport GO:0046942 147 95 0,000 0,29486522 0,29602357 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,29746076 0,29849901 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,29746076 0,29836883 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,29746076 0,29823877 ! protein maturation GO:0051604 129 96 0,000 0,29746076 0,29810882 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,30004689 0,30056962 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! extracellular structure organization GO:0043062 156 99 0,000 0,30519107 0,30558967 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,30519107 0,30545669 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,30774919 0,30788305 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,30774919 0,30774919