pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1007-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 3,000 3,394E-10 8,167E-07 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 3,000 1,41E-08 1,696E-05 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 3,000 2,21E-08 1,773E-05 ! regulation of JAK-STAT cascade GO:0046425 70 45 4,000 2,115E-07 1,272E-04 ! regulation of keratinocyte differentiation GO:0045616 6 5 2,000 2,4E-07 1,155E-04 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 4,781E-07 1,917E-04 ! positive regulation of muscle hypertrophy GO:0014742 10 6 2,000 4,79E-07 1,647E-04 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 3,000 8,213E-07 2,47E-04 ! regulation of epidermal cell differentiation GO:0045604 8 7 2,000 8,366E-07 2,236E-04 ! cytokine-mediated signaling pathway GO:0019221 97 59 4,000 8,393E-07 2,019E-04 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 2,000 1,336E-06 2,921E-04 GO:0016446|somatic hypermutation of immunoglobulin genes, ! UTP metabolic process GO:0046051 8 8 2,000 1,336E-06 2,678E-04 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! regulation of muscle hypertrophy GO:0014743 12 8 2,000 1,336E-06 2,472E-04 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of epidermis development GO:0045684 13 8 2,000 1,336E-06 2,295E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 1,59E-06 2,55E-04 ! CTP metabolic process GO:0046036 9 9 2,000 1,999E-06 3,006E-04 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 2,000 1,999E-06 2,83E-04 ! regulation of Notch signaling pathway GO:0008593 22 9 2,000 1,999E-06 2,672E-04 ! regulation of muscle adaptation GO:0043502 14 9 2,000 1,999E-06 2,532E-04 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 3,000 2,016E-06 2,425E-04 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 2,000 2,85E-06 3,265E-04 ! positive regulation of acute inflammatory response GO:0002675 16 10 2,000 2,85E-06 3,117E-04 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 3,000 2,951E-06 3,087E-04 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 3,609E-06 3,618E-04 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 3,000 3,732E-06 3,591E-04 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 4,084E-06 3,779E-04 GO:0045937|positive regulation of phosphate metabolic process, ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 2,000 5,203E-06 4,636E-04 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 3,000 5,738E-06 4,931E-04 ! regulation of acute inflammatory response GO:0002673 21 13 2,000 6,75E-06 5,6E-04 ! regulation of epidermis development GO:0045682 19 13 2,000 6,75E-06 5,413E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 7,697E-06 5,974E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 7,697E-06 5,787E-04 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 2,000 8,572E-06 6,25E-04 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 2,000 1,069E-05 7,567E-04 ! positive regulation of cytokine production GO:0001819 86 50 3,000 1,414E-05 9,721E-04 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 3,000 1,531E-05 1,023E-03 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 2,000 1,591E-05 1,035E-03 ! positive regulation of anti-apoptosis GO:0045768 39 18 2,000 1,905E-05 1,206E-03 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 2,000 2,258E-05 1,393E-03 ! regulation of bone remodeling GO:0046850 137 57 3,000 2,388E-05 1,436E-03 ! regulation of tissue remodeling GO:0034103 140 58 3,000 2,559E-05 1,502E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,651E-05 1,519E-03 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 2,000 2,651E-05 1,483E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 3,086E-05 1,688E-03 ! positive regulation of osteoblast differentiation GO:0045669 49 21 2,000 3,086E-05 1,65E-03 ! response to cytokine stimulus GO:0034097 63 21 2,000 3,086E-05 1,614E-03 ! positive regulation of adaptive immune response GO:0002821 39 22 2,000 3,566E-05 1,825E-03 ! somatic diversification of immunoglobulins GO:0016445 50 22 2,000 3,566E-05 1,787E-03 ! regulation of anti-apoptosis GO:0045767 53 23 2,000 4,092E-05 2,009E-03 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 2,000 4,092E-05 1,969E-03 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 2,000 4,667E-05 2,202E-03 GO:0016444|somatic cell DNA recombination, ! vasculogenesis GO:0001570 46 25 2,000 5,292E-05 2,449E-03 ! immunoglobulin production GO:0002377 55 25 2,000 5,292E-05 2,402E-03 GO:0002440|production of molecular mediator of immune response, ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 5,97E-05 2,66E-03 ! regulation of osteoblast differentiation GO:0045667 65 26 2,000 5,97E-05 2,611E-03 ! somatic diversification of immune receptors GO:0002200 56 26 2,000 5,97E-05 2,565E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 6,015E-05 2,539E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 8,393E-05 3,482E-03 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 1,000 8,393E-05 3,423E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 8,393E-05 3,366E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 8,393E-05 3,31E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 8,393E-05 3,257E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 8,393E-05 3,205E-03 ! metaphase plate congression GO:0051310 7 5 1,000 8,393E-05 3,155E-03 ! glial cell migration GO:0008347 11 5 1,000 8,393E-05 3,107E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 8,393E-05 3,06E-03 ! spindle assembly GO:0051225 6 5 1,000 8,393E-05 3,014E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 8,393E-05 2,97E-03 ! organ regeneration GO:0031100 7 5 1,000 8,393E-05 2,927E-03 ! response to hypoxia GO:0001666 171 81 3,000 9,535E-05 3,277E-03 ! positive regulation of T cell proliferation GO:0042102 52 31 2,000 1,021E-04 3,461E-03 ! response to oxygen levels GO:0070482 176 83 3,000 1,048E-04 3,504E-03 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 2,000 1,124E-04 3,706E-03 ! male meiosis GO:0007140 7 6 1,000 1,257E-04 4,085E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 1,000 1,257E-04 4,031E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 1,257E-04 3,978E-03 ! positive regulation of protein modification process GO:0031401 136 88 3,000 1,316E-04 4,111E-03 ! regulation of DNA binding GO:0051101 155 88 3,000 1,316E-04 4,059E-03 ! mismatch repair GO:0006298 46 34 2,000 1,351E-04 4,114E-03 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 2,000 1,351E-04 4,063E-03 ! tissue remodeling GO:0048771 76 37 2,000 1,743E-04 5,177E-03 ! glycogen metabolic process GO:0005977 61 37 2,000 1,743E-04 5,114E-03 ! prostate gland development GO:0030850 13 7 1,000 1,756E-04 5,09E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,756E-04 5,029E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 1,756E-04 4,97E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,756E-04 4,912E-03 GO:0043489|RNA stabilization, ! vesicle fusion GO:0006906 17 7 1,000 1,756E-04 4,856E-03 ! negative regulation of DNA recombination GO:0045910 15 7 1,000 1,756E-04 4,801E-03 ! axonal fasciculation GO:0007413 18 7 1,000 1,756E-04 4,747E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 1,756E-04 4,694E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 1,756E-04 4,642E-03 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 3,000 1,841E-04 4,816E-03 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 1,888E-04 4,885E-03 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 2,000 1,888E-04 4,834E-03 GO:0006073|cellular glucan metabolic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 3,000 1,916E-04 4,854E-03 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 3,000 1,994E-04 4,996E-03 ! mRNA catabolic process GO:0006402 71 39 2,000 2,041E-04 5,064E-03 ! ribonucleoside metabolic process GO:0009119 55 40 2,000 2,202E-04 5,407E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,337E-04 5,679E-03 ! meiotic prophase I GO:0007128 13 8 1,000 2,337E-04 5,622E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 2,337E-04 5,566E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,337E-04 5,512E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,337E-04 5,458E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 2,337E-04 5,406E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 2,337E-04 5,354E-03 ! establishment of chromosome localization GO:0051303 12 8 1,000 2,337E-04 5,304E-03 GO:0050000|chromosome localization, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 2,337E-04 5,254E-03 ! regulation of T cell proliferation GO:0042129 71 41 2,000 2,371E-04 5,282E-03 ! energy reserve metabolic process GO:0006112 74 43 2,000 2,734E-04 6,034E-03 ! axon extension GO:0048675 15 9 1,000 2,999E-04 6,559E-03 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 2,999E-04 6,499E-03 ! induction of positive chemotaxis GO:0050930 15 9 1,000 2,999E-04 6,441E-03 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 1,000 2,999E-04 6,384E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 2,999E-04 6,328E-03 ! receptor clustering GO:0043113 18 9 1,000 2,999E-04 6,273E-03 ! gas homeostasis GO:0033483 16 9 1,000 2,999E-04 6,219E-03 ! postreplication repair GO:0006301 22 9 1,000 2,999E-04 6,166E-03 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 2,999E-04 6,114E-03 ! cell growth GO:0016049 84 45 2,000 3,13E-04 6,328E-03 ! positive regulation of defense response GO:0031349 76 47 2,000 3,561E-04 7,141E-03 ! positive regulation of DNA binding GO:0043388 73 47 2,000 3,561E-04 7,082E-03 ! regulation of adaptive immune response GO:0002819 84 47 2,000 3,561E-04 7,024E-03 ! lung alveolus development GO:0048286 26 10 1,000 3,741E-04 7,318E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 3,741E-04 7,259E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 3,741E-04 7,201E-03 ! prophase GO:0051324 15 10 1,000 3,741E-04 7,144E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 3,741E-04 7,087E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 3,741E-04 7,032E-03 ! localization within membrane GO:0051668 20 10 1,000 3,741E-04 6,977E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,791E-04 7,016E-03 ! regulation of inflammatory response GO:0050727 75 48 2,000 3,791E-04 6,963E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 3,791E-04 6,91E-03 ! regulation of ossification GO:0030278 117 50 2,000 4,278E-04 7,739E-03 ! positive regulation of binding GO:0051099 78 51 2,000 4,536E-04 8,144E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 4,536E-04 8,083E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 4,564E-04 8,074E-03 ! blood vessel remodeling GO:0001974 29 11 1,000 4,564E-04 8,015E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 4,564E-04 7,957E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 4,564E-04 7,899E-03 ! temperature homeostasis GO:0001659 17 11 1,000 4,564E-04 7,843E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 4,564E-04 7,787E-03 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 1,000 4,564E-04 7,733E-03 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! RNA catabolic process GO:0006401 93 53 2,000 5,081E-04 8,548E-03 ! response to UV GO:0009411 104 53 2,000 5,081E-04 8,489E-03 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 5,466E-04 9,07E-03 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 5,466E-04 9,008E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 5,466E-04 8,946E-03 ! drug transport GO:0015893 16 12 1,000 5,466E-04 8,886E-03 ! immunoglobulin production during immune response GO:0002381 23 12 1,000 5,466E-04 8,826E-03 ! histone acetylation GO:0016573 26 12 1,000 5,466E-04 8,767E-03 ! gland morphogenesis GO:0022612 29 12 1,000 5,466E-04 8,709E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 5,466E-04 8,652E-03 ! regulation of RNA splicing GO:0043484 20 12 1,000 5,466E-04 8,596E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 5,466E-04 8,54E-03 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 5,666E-04 8,795E-03 ! positive regulation of organelle organization GO:0010638 100 56 2,000 5,974E-04 9,214E-03 ! positive regulation of cell migration GO:0030335 126 57 2,000 6,293E-04 9,643E-03 ! lipid localization GO:0010876 28 13 1,000 6,448E-04 9,818E-03 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 6,448E-04 9,756E-03 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 1,000 6,448E-04 9,695E-03 ! plasma membrane organization GO:0007009 24 13 1,000 6,448E-04 9,635E-03 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 6,448E-04 9,576E-03 ! regulation of mRNA stability GO:0043488 31 13 1,000 6,448E-04 9,517E-03 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 6,448E-04 9,459E-03 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 6,448E-04 9,402E-03 ! nucleoside metabolic process GO:0009116 81 60 2,000 7,313E-04 0,01059954 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 7,508E-04 0,01081668 ! non-recombinational repair GO:0000726 25 14 1,000 7,508E-04 0,01075229 GO:0006303|double-strand break repair via nonhomologous end joining, ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 7,508E-04 0,01068867 ! regulation of RNA stability GO:0043487 32 14 1,000 7,508E-04 0,0106258 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 8,646E-04 0,01216569 ! regulation of vasodilation GO:0042312 26 15 1,000 8,646E-04 0,01209496 ! positive regulation of cell motion GO:0051272 146 64 2,000 8,829E-04 0,0122793 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 9,863E-04 0,01363799 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 1,000 9,863E-04 0,01356005 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 9,863E-04 0,01348301 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 9,863E-04 0,01340683 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 9,863E-04 0,01333151 ! neuron recognition GO:0008038 35 16 1,000 9,863E-04 0,01325704 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 9,863E-04 0,01318339 ! lung development GO:0030324 144 67 2,000 1,009E-03 0,01340973 ! positive regulation of T cell activation GO:0050870 109 67 2,000 1,009E-03 0,01333606 ! adaptive immune response GO:0002250 119 67 2,000 1,009E-03 0,01326318 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 1,116E-03 0,01458862 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 1,116E-03 0,01450976 ! signal complex assembly GO:0007172 41 17 1,000 1,116E-03 0,01443175 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 1,116E-03 0,01435458 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 1,116E-03 0,01427822 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 1,116E-03 0,01420268 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,116E-03 0,01412793 ! respiratory tube development GO:0030323 150 70 2,000 1,145E-03 0,01442944 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 1,194E-03 0,01495608 ! respiratory system development GO:0060541 153 72 2,000 1,243E-03 0,01549288 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,253E-03 0,01553667 ! regulation of transcription factor activity GO:0051090 126 74 2,000 1,345E-03 0,01659692 GO:0090046|regulation of transcription regulator activity, ! positive regulation of angiogenesis GO:0045766 44 19 1,000 1,397E-03 0,01715471 ! lipid phosphorylation GO:0046834 35 19 1,000 1,397E-03 0,01706763 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 1,397E-03 0,01698143 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 1,397E-03 0,0168961 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 1,508E-03 0,01814567 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 1,55E-03 0,01855139 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,55E-03 0,01845955 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,55E-03 0,01836861 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 1,55E-03 0,01827857 ! regulation of interleukin-2 production GO:0032663 35 20 1,000 1,55E-03 0,01818941 ! sensory perception of pain GO:0019233 30 20 1,000 1,55E-03 0,01810111 ! reciprocal meiotic recombination GO:0007131 39 21 1,000 1,71E-03 0,01987208 ! inactivation of MAPK activity GO:0000188 39 21 1,000 1,71E-03 0,01977654 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 1,71E-03 0,01968192 ! regulation of vasoconstriction GO:0019229 39 21 1,000 1,71E-03 0,0195882 ! oogenesis GO:0048477 36 21 1,000 1,71E-03 0,01949536 ! positive regulation of locomotion GO:0040017 39 21 1,000 1,71E-03 0,0194034 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 40 22 1,000 1,877E-03 0,02120326 ! regeneration GO:0031099 41 22 1,000 1,877E-03 0,02110418 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 1,877E-03 0,02100602 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,877E-03 0,02090877 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,877E-03 0,02081241 ! protein stabilization GO:0050821 39 22 1,000 1,877E-03 0,02071694 ! negative regulation of transport GO:0051051 153 84 2,000 1,936E-03 0,02127065 ! positive regulation of cell activation GO:0050867 145 85 2,000 2,003E-03 0,0219026 GO:0002696|positive regulation of leukocyte activation, ! regulation of DNA recombination GO:0000018 48 23 1,000 2,052E-03 0,02233955 ! platelet activation GO:0030168 37 23 1,000 2,052E-03 0,02223892 ! negative regulation of catabolic process GO:0009895 50 23 1,000 2,052E-03 0,02213919 ! gland development GO:0048732 206 88 2,000 2,211E-03 0,02374983 ! vesicle docking GO:0048278 47 24 1,000 2,234E-03 0,0238918 ! regulation of behavior GO:0050795 43 24 1,000 2,234E-03 0,02378608 ! membrane depolarization GO:0051899 39 24 1,000 2,234E-03 0,0236813 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,234E-03 0,02357743 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 2,424E-03 0,02546739 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 2,424E-03 0,02535666 ! receptor metabolic process GO:0043112 46 25 1,000 2,424E-03 0,02524689 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 2,424E-03 0,02513807 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 2,424E-03 0,02503018 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 1,000 2,424E-03 0,02492321 ! regulation of blood coagulation GO:0030193 40 25 1,000 2,424E-03 0,02481715 ! regulation of defense response GO:0031347 149 92 2,000 2,509E-03 0,02558139 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 2,587E-03 0,02626743 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 2,621E-03 0,02649607 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 2,621E-03 0,02638521 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 2,621E-03 0,02627527 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 2,621E-03 0,02616625 ! positive regulation of nuclear division GO:0051785 40 26 1,000 2,621E-03 0,02605812 GO:0045840|positive regulation of mitosis, ! regulation of T cell activation GO:0050863 158 94 2,000 2,667E-03 0,02640801 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 2,825E-03 0,02785923 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,825E-03 0,02774551 ! protein amino acid acylation GO:0043543 55 27 1,000 2,825E-03 0,02763273 ! positive regulation of immune response GO:0050778 156 96 2,000 2,831E-03 0,02757708 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 1,000 3,037E-03 0,02946244 ! skeletal muscle tissue development GO:0007519 186 99 2,000 3,088E-03 0,02984187 GO:0060538|skeletal muscle organ development, ! respiratory gaseous exchange GO:0007585 57 29 1,000 3,256E-03 0,03133226 ! sterol biosynthetic process GO:0016126 52 29 1,000 3,256E-03 0,03120743 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 3,256E-03 0,03108359 ! regulation of coagulation GO:0050818 46 29 1,000 3,256E-03 0,03096073 ! membrane docking GO:0022406 61 30 1,000 3,482E-03 0,03297907 ! acute-phase response GO:0006953 49 30 1,000 3,482E-03 0,03284974 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 3,482E-03 0,03272142 ! cholesterol homeostasis GO:0042632 53 31 1,000 3,715E-03 0,03477603 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 43 31 1,000 3,715E-03 0,03464124 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 3,715E-03 0,03450749 GO:0043433|negative regulation of transcription factor activity, ! cholesterol transport GO:0030301 56 32 1,000 3,955E-03 0,03659705 ! spindle organization GO:0007051 46 32 1,000 3,955E-03 0,03645683 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 3,955E-03 0,03631769 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 3,955E-03 0,0361796 ! sterol transport GO:0015918 57 33 1,000 4,202E-03 0,0382953 ! negative regulation of protein transport GO:0051224 69 33 1,000 4,202E-03 0,03815079 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 4,717E-03 0,04266845 ! negative regulation of secretion GO:0051048 63 35 1,000 4,717E-03 0,04250865 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 4,717E-03 0,04235003 ! neutral lipid metabolic process GO:0006638 50 35 1,000 4,717E-03 0,0421926 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 4,717E-03 0,04203633 ! regulation of microtubule-based process GO:0032886 78 35 1,000 4,717E-03 0,04188121 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 4,985E-03 0,04409826 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 4,985E-03 0,04393673 ! meiosis I GO:0007127 65 37 1,000 5,26E-03 0,04619043 ! negative regulation of DNA binding GO:0043392 68 37 1,000 5,26E-03 0,04602246 ! glycerol ether metabolic process GO:0006662 53 37 1,000 5,26E-03 0,04585571 ! regulation of protein stability GO:0031647 73 37 1,000 5,26E-03 0,04569017 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 5,26E-03 0,04552582 ! lipid homeostasis GO:0055088 67 38 1,000 5,542E-03 0,04779232 ! mammary gland development GO:0030879 86 39 1,000 5,831E-03 0,05010095 ! organic ether metabolic process GO:0018904 55 39 1,000 5,831E-03 0,04992266 ! segmentation GO:0035282 67 39 1,000 5,831E-03 0,04974562 ! regulation of hormone secretion GO:0046883 62 40 1,000 6,126E-03 0,05208024 ! negative regulation of binding GO:0051100 72 40 1,000 6,126E-03 0,05189686 ! maintenance of protein location GO:0045185 91 40 1,000 6,126E-03 0,05171476 ! gliogenesis GO:0042063 88 41 1,000 6,428E-03 0,05407441 ! female gamete generation GO:0007292 61 41 1,000 6,428E-03 0,053886 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 6,736E-03 0,0562774 GO:0090047|positive regulation of transcription regulator activity, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 6,736E-03 0,05608267 ! neuron migration GO:0001764 79 42 1,000 6,736E-03 0,05588928 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 6,736E-03 0,05569722 ! double-strand break repair GO:0006302 81 44 1,000 7,374E-03 0,06075624 ! maintenance of location in cell GO:0051651 97 44 1,000 7,374E-03 0,06054888 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 7,702E-03 0,06303045 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 7,702E-03 0,06281679 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 8,037E-03 0,06532678 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 8,037E-03 0,06510683 ! response to insulin stimulus GO:0032868 95 46 1,000 8,037E-03 0,06488835 ! positive regulation of protein transport GO:0051222 72 46 1,000 8,037E-03 0,06467133 ! endosome transport GO:0016197 108 47 1,000 8,378E-03 0,06719351 ! vascular process in circulatory system GO:0003018 80 47 1,000 8,378E-03 0,06697028 ! protein homooligomerization GO:0051260 76 47 1,000 8,378E-03 0,06674852 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 9,08E-03 0,07210223 GO:0019724|B cell mediated immunity, ! histone modification GO:0016570 91 50 1,000 9,441E-03 0,07471836 ! vesicle organization GO:0016050 107 51 1,000 9,808E-03 0,07736707 ! regulation of cell shape GO:0008360 125 51 1,000 9,808E-03 0,07711424 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01018064 0,079787 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,01018064 0,07952795 ! membrane fusion GO:0006944 110 52 1,000 0,01018064 0,07927058 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01018064 0,07901487 ! amino acid activation GO:0043038 92 52 1,000 0,01018064 0,0787608 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! regulation of translational initiation GO:0006446 82 53 1,000 0,01055995 0,08143347 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,01055995 0,0811733 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,01055995 0,08091479 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01094546 0,08360244 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 1,000 0,01094546 0,08333788 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01133711 0,08604761 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,01133711 0,08577702 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,01213872 0,0915541 ! lipid modification GO:0030258 97 57 1,000 0,01213872 0,09126799 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01213872 0,09098367 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,01213872 0,09070111 ! maintenance of location GO:0051235 118 57 1,000 0,01213872 0,0904203 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01254859 0,09318494 ! establishment of organelle localization GO:0051656 109 59 1,000 0,01296447 0,09597696 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,0133863 0,09879583 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,0133863 0,0984937 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,01381406 0,10133116 ! tRNA processing GO:0008033 89 61 1,000 0,01381406 0,10102316 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,01381406 0,10071703 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,0142477 0,10356483 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01452552 0,10526627 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01452552 0,10495015 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01452552 0,10463593 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01452552 0,10432358 ! neuron fate determination GO:0048664 7 5 0,000 0,01452552 0,1040131 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01452552 0,10370445 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01452552 0,10339763 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01452552 0,10309263 ! polyol transport GO:0015791 12 5 0,000 0,01452552 0,10278941 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01452552 0,10248798 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01452552 0,10218831 ! response to superoxide GO:0000303 10 5 0,000 0,01452552 0,10189038 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01452552 0,10159419 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01452552 0,10129971 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01452552 0,10100694 ! female meiosis GO:0007143 7 5 0,000 0,01452552 0,10071585 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01452552 0,10042644 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01452552 0,10013868 ! cobalt ion transport GO:0006824 11 5 0,000 0,01452552 0,09985257 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01452552 0,09956809 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01452552 0,09928523 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01452552 0,09900397 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01452552 0,0987243 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01452552 0,0984462 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01452552 0,09816966 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01452552 0,09789468 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01452552 0,09762123 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01452552 0,09734931 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01452552 0,09707889 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01452552 0,09680997 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01452552 0,09654254 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01452552 0,09627659 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01452552 0,09601209 ! negative chemotaxis GO:0050919 14 5 0,000 0,01452552 0,09574904 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01452552 0,09548743 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01452552 0,09522725 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01452552 0,09496848 ! behavioral response to pain GO:0048266 9 5 0,000 0,01452552 0,09471111 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01452552 0,09445514 ! Notch receptor processing GO:0007220 8 5 0,000 0,01452552 0,09420054 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01452552 0,09394731 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01452552 0,09369544 ! micturition GO:0060073 9 5 0,000 0,01452552 0,09344492 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01452552 0,09319573 ! copulation GO:0007620 9 5 0,000 0,01452552 0,09294787 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01452552 0,09270133 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01452552 0,09245609 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01452552 0,09221214 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01452552 0,09196948 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01452552 0,09172809 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01452552 0,09148796 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01452552 0,09124909 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01452552 0,09101146 ! grooming behavior GO:0007625 6 5 0,000 0,01452552 0,09077507 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01452552 0,0905399 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01452552 0,09030594 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01452552 0,0900732 ! response to protozoan GO:0001562 10 5 0,000 0,01452552 0,08984165 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01452552 0,08961128 ! lymph vessel development GO:0001945 10 5 0,000 0,01452552 0,0893821 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01452552 0,08915408 ! endochondral ossification GO:0001958 16 5 0,000 0,01452552 0,08892723 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01452552 0,08870152 ! parathyroid gland development GO:0060017 13 5 0,000 0,01452552 0,08847696 ! anagen GO:0042640 6 5 0,000 0,01452552 0,08825354 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01452552 0,08803124 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01452552 0,08781005 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01452552 0,08758998 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01452552 0,087371 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01452552 0,08715312 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01452552 0,08693632 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01452552 0,0867206 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01452552 0,08650594 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01452552 0,08629235 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01452552 0,0860798 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01452552 0,08586831 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01452552 0,08565784 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01452552 0,08544841 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01452552 0,08524 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01452552 0,0850326 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01452552 0,08482622 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01452552 0,08462082 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01452552 0,08441643 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01452552 0,08421301 ! histidine catabolic process GO:0006548 6 5 0,000 0,01452552 0,08401058 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01452552 0,08380911 ! microvillus organization GO:0032528 7 5 0,000 0,01452552 0,08360861 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01452552 0,08340907 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01452552 0,08321048 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01452552 0,08301283 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01452552 0,08281612 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01452552 0,08262033 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01452552 0,08242547 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01452552 0,08223153 ! polyol catabolic process GO:0046174 7 5 0,000 0,01452552 0,0820385 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01452552 0,08184637 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01452552 0,08165514 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01452552 0,0814648 ! muscle cell migration GO:0014812 8 5 0,000 0,01452552 0,08127535 ! mitochondrial fission GO:0000266 8 5 0,000 0,01452552 0,08108678 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01452552 0,08089908 ! mRNA transcription GO:0009299 9 5 0,000 0,01452552 0,08071224 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01452552 0,08052627 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01452552 0,08034115 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01452552 0,08015688 GO:0051489|regulation of filopodium assembly, ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01452552 0,07997346 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01452552 0,07979087 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01452552 0,07960911 ! response to food GO:0032094 6 5 0,000 0,01452552 0,07942818 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01452552 0,07924807 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01452552 0,07906878 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01452552 0,07889029 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01452552 0,07871261 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01452552 0,07853573 ! forebrain neuron development GO:0021884 13 5 0,000 0,01452552 0,07835964 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01452552 0,07818434 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01452552 0,07800982 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01452552 0,07783608 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01452552 0,07766311 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01452552 0,07749091 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01452552 0,07731947 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01452552 0,07714879 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01452552 0,07697886 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01452552 0,07680967 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01452552 0,07664123 ! basic amino acid transport GO:0015802 11 5 0,000 0,01452552 0,07647352 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01452552 0,07630655 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01452552 0,07614031 ! depyrimidination GO:0045008 10 5 0,000 0,01452552 0,07597478 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01452552 0,07580998 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01452552 0,07564589 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01452552 0,07548251 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01452552 0,07531983 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01452552 0,07515785 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01452552 0,07499657 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01452552 0,07483598 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01452552 0,07467607 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01452552 0,07451685 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01452552 0,0743583 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01452552 0,07420043 ! response to arsenic GO:0046685 10 5 0,000 0,01452552 0,07404322 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01452552 0,07388668 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01452552 0,0737308 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01452552 0,07357558 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01452552 0,07342101 ! response to cadmium ion GO:0046686 7 5 0,000 0,01452552 0,07326709 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01452552 0,07311381 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01452552 0,07296117 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01452552 0,07280917 ! decidualization GO:0046697 11 5 0,000 0,01452552 0,0726578 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01452552 0,07250706 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01452552 0,07235694 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01452552 0,07220744 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01452552 0,07205856 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01452552 0,07191029 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01452552 0,07176263 ! neural tube patterning GO:0021532 7 5 0,000 0,01452552 0,07161557 ! embryonic cleavage GO:0040016 6 5 0,000 0,01452552 0,07146912 ! peroxisome fission GO:0016559 5 5 0,000 0,01452552 0,07132327 ! histone demethylation GO:0016577 10 5 0,000 0,01452552 0,07117801 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01452552 0,07103333 ! mitotic recombination GO:0006312 9 5 0,000 0,01452552 0,07088925 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01452552 0,07074575 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01452552 0,07060283 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01452552 0,07046049 ! enteric nervous system development GO:0048484 8 5 0,000 0,01452552 0,07031871 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01452552 0,07017751 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01452552 0,07003687 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01452552 0,0698968 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01452552 0,06975729 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01452552 0,06961833 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01452552 0,06947992 ! plasminogen activation GO:0031639 5 5 0,000 0,01452552 0,06934206 ! B cell homeostasis GO:0001782 13 5 0,000 0,01452552 0,06920475 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01452552 0,06906799 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01452552 0,06893176 ! metaphase GO:0051323 8 5 0,000 0,01452552 0,06879606 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01452552 0,0686609 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01452552 0,06852628 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01452552 0,06839217 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01452552 0,06825859 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01452552 0,06812554 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01452552 0,067993 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01452552 0,06786097 ! response to redox state GO:0051775 5 5 0,000 0,01452552 0,06772946 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01452552 0,06759845 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01452552 0,06746795 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01452552 0,06733796 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01452552 0,06720846 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01452552 0,06707946 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01452552 0,06695096 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01452552 0,06682295 ! striatum development GO:0021756 9 5 0,000 0,01452552 0,06669542 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01452552 0,06656838 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01452552 0,06644183 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01452552 0,06631575 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01452552 0,06619015 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01452552 0,06606503 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01452552 0,06594038 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01452552 0,0658162 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01452552 0,06569248 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01452552 0,06556923 ! neuroprotection GO:0043526 6 5 0,000 0,01452552 0,06544644 ! neural plate development GO:0001840 8 5 0,000 0,01452552 0,06532411 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01452552 0,06520224 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01452552 0,06508082 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01452552 0,06495985 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01452552 0,06483933 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01452552 0,06471926 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01452552 0,06459963 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01452552 0,06448044 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01452552 0,0643617 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01452552 0,06424338 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01452552 0,06412551 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01452552 0,06400806 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01452552 0,06389104 ! drug metabolic process GO:0017144 6 5 0,000 0,01452552 0,06377445 ! stem cell division GO:0017145 11 5 0,000 0,01452552 0,06365829 GO:0048103|somatic stem cell division, ! carnitine metabolic process GO:0009437 7 5 0,000 0,01452552 0,06354255 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01452552 0,06342722 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01452552 0,06331232 ! regulation of mitosis GO:0007088 105 63 1,000 0,01468719 0,06390121 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,01468719 0,06378586 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,01468719 0,06367093 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,01513248 0,06548337 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,01558356 0,06731425 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,01604037 0,0691633 ! actin filament organization GO:0007015 148 66 1,000 0,01604037 0,06903957 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,01650288 0,07090343 ! chromosome segregation GO:0007059 113 67 1,000 0,01650288 0,07077704 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,01697105 0,07265542 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01697105 0,07252637 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01740549 0,07425109 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01740549 0,07411967 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01740549 0,07398872 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01740549 0,07385823 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01740549 0,0737282 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01740549 0,07359862 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01740549 0,0734695 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01740549 0,07334083 ! sleep GO:0030431 13 6 0,000 0,01740549 0,07321262 ! response to oxygen radical GO:0000305 11 6 0,000 0,01740549 0,07308485 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01740549 0,07295752 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01740549 0,07283064 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01740549 0,07270419 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01740549 0,07257819 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01740549 0,07245262 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01740549 0,07232749 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01740549 0,07220279 ! forebrain regionalization GO:0021871 8 6 0,000 0,01740549 0,07207851 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01740549 0,07195467 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01740549 0,07183125 ! response to zinc ion GO:0010043 9 6 0,000 0,01740549 0,07170825 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01740549 0,07158567 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01740549 0,07146351 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01740549 0,07134177 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01740549 0,07122044 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01740549 0,07109952 ! malate metabolic process GO:0006108 11 6 0,000 0,01740549 0,07097901 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01740549 0,07085891 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01740549 0,07073922 ! protein refolding GO:0042026 15 6 0,000 0,01740549 0,07061993 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01740549 0,07050104 ! opsonization GO:0008228 8 6 0,000 0,01740549 0,07038255 ! mating behavior GO:0007617 7 6 0,000 0,01740549 0,07026446 ! neuron remodeling GO:0016322 15 6 0,000 0,01740549 0,07014676 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01740549 0,07002946 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01740549 0,06991255 ! equilibrioception GO:0050957 14 6 0,000 0,01740549 0,06979603 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01740549 0,06967989 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01740549 0,06956415 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01740549 0,06944878 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01740549 0,0693338 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01740549 0,0692192 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01740549 0,06910498 ! toxin metabolic process GO:0009404 11 6 0,000 0,01740549 0,06899113 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01740549 0,06887766 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01740549 0,06876456 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01740549 0,06865183 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01740549 0,06853947 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01740549 0,06842748 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01740549 0,06831585 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01740549 0,06820459 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01740549 0,06809368 ! thymic T cell selection GO:0045061 12 6 0,000 0,01740549 0,06798314 ! protein lipoylation GO:0009249 10 6 0,000 0,01740549 0,06787296 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01740549 0,06776313 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01740549 0,06765366 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01740549 0,06754454 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01740549 0,06743577 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01740549 0,06732736 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01740549 0,06721929 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01740549 0,06711156 ! response to pH GO:0009268 10 6 0,000 0,01740549 0,06700419 ! hyperosmotic response GO:0006972 9 6 0,000 0,01740549 0,06689715 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01740549 0,06679046 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01740549 0,0666841 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01740549 0,06657809 ! urea metabolic process GO:0019627 7 6 0,000 0,01740549 0,06647241 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01740549 0,06636706 ! neutrophil activation GO:0042119 8 6 0,000 0,01740549 0,06626205 ! regulation of appetite GO:0032098 9 6 0,000 0,01740549 0,06615737 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01740549 0,06605302 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01740549 0,065949 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01740549 0,06584531 ! neuron apoptosis GO:0051402 9 6 0,000 0,01740549 0,06574194 ! nucleoside salvage GO:0043174 9 6 0,000 0,01740549 0,0656389 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01740549 0,06553618 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01740549 0,06543378 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01740549 0,06533169 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01740549 0,06522993 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01740549 0,06512849 ! carnitine transport GO:0015879 10 6 0,000 0,01740549 0,06502735 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01740549 0,06492654 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01740549 0,06482603 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01740549 0,06472584 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01740549 0,06462595 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01740549 0,06452637 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01740549 0,0644271 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01740549 0,06432814 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01740549 0,06422947 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01740549 0,06413111 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01740549 0,06403305 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01740549 0,06393529 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01740549 0,06383783 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01740549 0,06374066 ! neural nucleus development GO:0048857 14 6 0,000 0,01740549 0,06364379 ! response to UV-C GO:0010225 11 6 0,000 0,01740549 0,06354722 ! astrocyte development GO:0014002 15 6 0,000 0,01740549 0,06345093 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01740549 0,06335494 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01740549 0,06325924 ! interaction with symbiont GO:0051702 13 6 0,000 0,01740549 0,06316383 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01740549 0,0630687 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01740549 0,06297386 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01740549 0,0628793 ! response to copper ion GO:0046688 10 6 0,000 0,01740549 0,06278503 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01740549 0,06269104 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01740549 0,06259733 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01740549 0,0625039 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01740549 0,06241075 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01740549 0,06231788 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01740549 0,06222528 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01740549 0,06213296 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01740549 0,06204091 ! hair follicle maturation GO:0048820 7 6 0,000 0,01740549 0,06194914 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01740549 0,06185763 ! Schwann cell development GO:0014044 15 6 0,000 0,01740549 0,0617664 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01740549 0,06167543 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01740549 0,06158473 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01740549 0,0614943 ! subpallium development GO:0021544 10 6 0,000 0,01740549 0,06140413 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01740549 0,06131423 ! histone ubiquitination GO:0016574 8 6 0,000 0,01740549 0,06122459 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01740549 0,06113521 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01740549 0,06104609 ! G2 phase GO:0051319 16 6 0,000 0,01740549 0,06095723 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01740549 0,06086863 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01740549 0,06078028 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01740549 0,0606922 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01740549 0,06060436 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01740549 0,06051679 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01740549 0,06042946 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01740549 0,06034239 ! receptor internalization GO:0031623 10 6 0,000 0,01740549 0,06025556 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01740549 0,06016899 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01740549 0,06008266 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01740549 0,05999658 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01740549 0,05991075 ! protein deubiquitination GO:0016579 14 6 0,000 0,01740549 0,05982517 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01740549 0,05973982 ! protein destabilization GO:0031648 9 6 0,000 0,01740549 0,05965472 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01740549 0,05956987 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01740549 0,05948525 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01740549 0,05940087 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01740549 0,05931674 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01740549 0,05923284 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01740549 0,05914918 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01740549 0,05906575 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01740549 0,05898256 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01740549 0,0588996 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01740549 0,05881688 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01740549 0,05873438 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01740549 0,05865212 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01740549 0,05857009 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01740549 0,05848829 ! catecholamine transport GO:0051937 9 6 0,000 0,01740549 0,05840672 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01740549 0,05832537 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01740549 0,05824425 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01740549 0,05816336 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01740549 0,05808269 ! maternal placenta development GO:0001893 12 6 0,000 0,01740549 0,05800224 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01740549 0,05792201 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01740549 0,05784201 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01740549 0,05776223 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01740549 0,05768267 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01740549 0,05760332 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01740549 0,0575242 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,01744485 0,05757519 ! urogenital system development GO:0001655 137 69 1,000 0,01744485 0,05749632 ! reproductive structure development GO:0048608 113 71 1,000 0,01840919 0,06059168 ! B cell activation GO:0042113 160 71 1,000 0,01840919 0,06050891 ! acute inflammatory response GO:0002526 113 72 1,000 0,01889966 0,06203627 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01889966 0,06195175 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,01889966 0,06186747 ! meiosis GO:0007126 121 74 1,000 0,01989702 0,06504378 GO:0051327|M phase of meiotic cell cycle, ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,01989702 0,06495553 ! organelle localization GO:0051640 136 74 1,000 0,01989702 0,06486751 ! tRNA transcription GO:0009304 14 7 0,000 0,02027715 0,06601734 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02027715 0,06592812 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02027715 0,06583915 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02027715 0,06575042 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02027715 0,06566193 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02027715 0,06557367 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02027715 0,06548565 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02027715 0,06539787 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02027715 0,06531032 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02027715 0,06522301 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02027715 0,06513593 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02027715 0,06504908 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02027715 0,06496246 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02027715 0,06487608 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02027715 0,06478992 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02027715 0,06470399 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02027715 0,06461829 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02027715 0,06453282 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02027715 0,06444757 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02027715 0,06436255 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02027715 0,06427775 ! glycolipid transport GO:0046836 10 7 0,000 0,02027715 0,06419317 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02027715 0,06410882 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02027715 0,06402469 ! neuron adhesion GO:0007158 12 7 0,000 0,02027715 0,06394077 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02027715 0,06385708 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02027715 0,06377361 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02027715 0,06369035 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02027715 0,06360732 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02027715 0,06352449 ! pericardium development GO:0060039 14 7 0,000 0,02027715 0,06344189 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02027715 0,0633595 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02027715 0,06327732 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02027715 0,06319535 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02027715 0,0631136 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02027715 0,06303206 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02027715 0,06295072 ! lipoprotein transport GO:0042953 14 7 0,000 0,02027715 0,0628696 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02027715 0,06278869 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02027715 0,06270798 ! rhythmic behavior GO:0007622 15 7 0,000 0,02027715 0,06262749 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02027715 0,06254719 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02027715 0,06246711 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02027715 0,06238723 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02027715 0,06230755 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02027715 0,06222808 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02027715 0,0621488 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02027715 0,06206973 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02027715 0,06199087 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02027715 0,0619122 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02027715 0,06183373 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02027715 0,06175546 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02027715 0,06167738 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02027715 0,06159951 ! spinal cord patterning GO:0021511 13 7 0,000 0,02027715 0,06152183 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02027715 0,06144435 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02027715 0,06136706 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02027715 0,06128996 ! adrenal gland development GO:0030325 17 7 0,000 0,02027715 0,06121306 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02027715 0,06113635 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02027715 0,06105984 ! ovulation GO:0030728 9 7 0,000 0,02027715 0,06098351 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02027715 0,06090738 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02027715 0,06083144 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02027715 0,06075568 ! microtubule nucleation GO:0007020 20 7 0,000 0,02027715 0,06068011 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02027715 0,06060473 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02027715 0,06052954 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02027715 0,06045454 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02027715 0,06037972 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02027715 0,06030508 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02027715 0,06023063 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02027715 0,06015636 ! galactose metabolic process GO:0006012 13 7 0,000 0,02027715 0,06008228 ! response to dietary excess GO:0002021 8 7 0,000 0,02027715 0,06000838 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02027715 0,05993466 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02027715 0,05986112 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02027715 0,05978776 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02027715 0,05971458 ! organ growth GO:0035265 15 7 0,000 0,02027715 0,05964158 ! purine salvage GO:0043101 10 7 0,000 0,02027715 0,05956876 ! nucleoside transport GO:0015858 8 7 0,000 0,02027715 0,05949611 ! parturition GO:0007567 14 7 0,000 0,02027715 0,05942364 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02027715 0,05935135 ! rRNA modification GO:0000154 14 7 0,000 0,02027715 0,05927924 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02027715 0,0592073 ! spindle checkpoint GO:0031577 15 7 0,000 0,02027715 0,05913553 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02027715 0,05906394 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02027715 0,05899252 ! macrophage differentiation GO:0030225 11 7 0,000 0,02027715 0,05892127 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02027715 0,05885019 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02027715 0,05877929 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02027715 0,05870856 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02027715 0,05863799 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02027715 0,0585676 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02027715 0,05849738 ! fibrinolysis GO:0042730 10 7 0,000 0,02027715 0,05842732 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02027715 0,05835743 ! eating behavior GO:0042755 7 7 0,000 0,02027715 0,05828771 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02027715 0,05821815 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02027715 0,05814876 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02027715 0,05807954 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02027715 0,05801048 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02027715 0,05794158 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02027715 0,05787285 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02027715 0,05780428 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02027715 0,05773587 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02027715 0,05766763 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02027715 0,05759954 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02027715 0,05753162 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02027715 0,05746385 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02027715 0,05739625 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02027715 0,0573288 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02027715 0,05726152 ! regulation of meiosis GO:0040020 12 7 0,000 0,02027715 0,05719439 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02027715 0,05712741 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02027715 0,0570606 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02027715 0,05699394 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02027715 0,05692743 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02027715 0,05686109 ! transcription termination GO:0006353 13 7 0,000 0,02027715 0,05679489 ! response to tumor cell GO:0002347 13 7 0,000 0,02027715 0,05672885 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02027715 0,05666296 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02027715 0,05659723 ! anaphase GO:0051322 17 7 0,000 0,02027715 0,05653165 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02027715 0,05646622 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02027715 0,05640094 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02027715 0,05633581 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02027715 0,05627083 ! diuresis GO:0030146 12 7 0,000 0,02027715 0,056206 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02027715 0,05614132 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02027715 0,05607679 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02027715 0,05601241 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02027715 0,05594818 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02027715 0,05588409 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02027715 0,05582015 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02027715 0,05575636 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02027715 0,05569271 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02027715 0,0556292 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02027715 0,05556584 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02027715 0,05550263 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02027715 0,05543956 ! lymph node development GO:0048535 10 7 0,000 0,02027715 0,05537663 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02027715 0,05531384 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02027715 0,0552512 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02027715 0,0551887 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02027715 0,05512634 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02027715 0,05506412 ! adult feeding behavior GO:0008343 9 7 0,000 0,02027715 0,05500204 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02027715 0,0549401 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02027715 0,0548783 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02027715 0,05481664 ! muscle adaptation GO:0043500 14 7 0,000 0,02027715 0,05475512 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02027715 0,05469373 ! retina homeostasis GO:0001895 12 7 0,000 0,02027715 0,05463249 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02027715 0,05457138 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02027715 0,0545104 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02027715 0,05444957 ! protein prenylation GO:0018342 18 7 0,000 0,02027715 0,05438886 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02027715 0,0543283 ! meiotic cell cycle GO:0051321 122 75 1,000 0,02040383 0,05460692 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,02091603 0,05591551 ! regulation of catabolic process GO:0009894 161 76 1,000 0,02091603 0,05585346 ! blood coagulation GO:0007596 146 78 1,000 0,02195641 0,05856666 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 1,000 0,02195641 0,0585018 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02248453 0,05984268 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,02301789 0,06119453 ! protein import into nucleus GO:0006606 158 80 1,000 0,02301789 0,06112698 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0231405 0,06138483 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0231405 0,06131723 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0231405 0,06124977 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0231405 0,06118246 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0231405 0,0611153 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0231405 0,06104829 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0231405 0,06098143 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0231405 0,06091471 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0231405 0,06084813 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0231405 0,06078171 ! oligopeptide transport GO:0006857 15 8 0,000 0,0231405 0,06071542 ! signal peptide processing GO:0006465 12 8 0,000 0,0231405 0,06064928 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0231405 0,06058329 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0231405 0,06051744 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0231405 0,06045173 ! succinate metabolic process GO:0006105 14 8 0,000 0,0231405 0,06038616 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0231405 0,06032074 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0231405 0,06025546 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0231405 0,06019032 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0231405 0,06012532 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0231405 0,06006046 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0231405 0,05999574 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0231405 0,05993115 ! reflex GO:0060004 16 8 0,000 0,0231405 0,05986671 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0231405 0,05980241 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0231405 0,05973824 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0231405 0,05967422 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0231405 0,05961032 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0231405 0,05954657 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0231405 0,05948295 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0231405 0,05941947 ! pigment granule organization GO:0048753 16 8 0,000 0,0231405 0,05935612 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0231405 0,05929291 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0231405 0,05922983 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0231405 0,05916689 ! histidine metabolic process GO:0006547 16 8 0,000 0,0231405 0,05910408 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0231405 0,0590414 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0231405 0,05897886 ! glycine catabolic process GO:0006546 13 8 0,000 0,0231405 0,05891645 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0231405 0,05885417 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0231405 0,05879202 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,0231405 0,05873 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0231405 0,05866812 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0231405 0,05860636 ! melanin metabolic process GO:0006582 15 8 0,000 0,0231405 0,05854473 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0231405 0,05848324 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0231405 0,05842187 ! macrophage activation GO:0042116 12 8 0,000 0,0231405 0,05836063 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0231405 0,05829952 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0231405 0,05823854 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0231405 0,05817768 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0231405 0,05811695 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0231405 0,05805635 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0231405 0,05799588 ! osteoblast development GO:0002076 16 8 0,000 0,0231405 0,05793553 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0231405 0,0578753 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0231405 0,05781521 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0231405 0,05775523 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0231405 0,05769538 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0231405 0,05763565 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0231405 0,05757605 ! response to UV-B GO:0010224 16 8 0,000 0,0231405 0,05751657 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0231405 0,05745722 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0231405 0,05739798 ! intermediate filament organization GO:0045109 12 8 0,000 0,0231405 0,05733887 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0231405 0,05727988 ! cellular extravasation GO:0045123 12 8 0,000 0,0231405 0,05722101 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0231405 0,05716226 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0231405 0,05710363 ! response to antibiotic GO:0046677 11 8 0,000 0,0231405 0,05704513 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0231405 0,05698674 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0231405 0,05692847 ! DNA topological change GO:0006265 12 8 0,000 0,0231405 0,05687032 ! response to tropane GO:0014073 15 8 0,000 0,0231405 0,05681229 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0231405 0,05675438 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,0231405 0,05669658 ! melanosome transport GO:0032402 13 8 0,000 0,0231405 0,0566389 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0231405 0,05658134 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0231405 0,0565239 ! mast cell activation GO:0045576 14 8 0,000 0,0231405 0,05646657 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0231405 0,05640936 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0231405 0,05635227 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0231405 0,05629529 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0231405 0,05623843 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0231405 0,05618168 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0231405 0,05612504 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0231405 0,05606852 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0231405 0,05601212 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0231405 0,05595582 ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0231405 0,05589964 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0231405 0,05584357 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0231405 0,05578762 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0231405 0,05573177 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0231405 0,05567604 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0231405 0,05562042 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0231405 0,05556491 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0231405 0,05550951 ! hormone catabolic process GO:0042447 17 8 0,000 0,0231405 0,05545423 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0231405 0,05539905 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0231405 0,05534398 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0231405 0,05528902 ! ATP catabolic process GO:0006200 11 8 0,000 0,0231405 0,05523417 ! blastocyst growth GO:0001832 19 8 0,000 0,0231405 0,05517943 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0231405 0,05512479 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0231405 0,05507027 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0231405 0,05501585 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0231405 0,05496154 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0231405 0,05490734 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0231405 0,05485324 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0231405 0,05479925 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0231405 0,05474537 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0231405 0,05469159 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0231405 0,05463792 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0231405 0,05458436 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0231405 0,05453089 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0231405 0,05447754 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0231405 0,05442428 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0231405 0,05437114 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0231405 0,05431809 ! nuclear import GO:0051170 161 81 1,000 0,02355646 0,05524058 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,02410019 0,05646062 ! response to drug GO:0042493 143 82 1,000 0,02410019 0,0564057 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,02410019 0,05635088 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,02410019 0,05629617 ! regulation of lyase activity GO:0051339 160 83 1,000 0,02464906 0,05752245 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,02520304 0,05875824 ! hemostasis GO:0007599 158 84 1,000 0,02520304 0,05870136 ! regulation of developmental growth GO:0048638 15 9 0,000 0,02599558 0,06048875 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02599558 0,06043031 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02599558 0,06037198 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02599558 0,06031376 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02599558 0,06025565 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02599558 0,06019766 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02599558 0,06013978 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02599558 0,06008201 ! phosphate transport GO:0006817 19 9 0,000 0,02599558 0,06002435 ! reproductive behavior GO:0019098 19 9 0,000 0,02599558 0,0599668 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02599558 0,05990936 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02599558 0,05985203 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02599558 0,05979481 ! RNA methylation GO:0001510 15 9 0,000 0,02599558 0,0597377 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02599558 0,05968069 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02599558 0,0596238 ! artery development GO:0060840 24 9 0,000 0,02599558 0,05956702 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02599558 0,05951034 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02599558 0,05945377 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02599558 0,05939731 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02599558 0,05934096 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02599558 0,05928471 ! chemosensory behavior GO:0007635 20 9 0,000 0,02599558 0,05922857 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02599558 0,05917253 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02599558 0,0591166 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02599558 0,05906078 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02599558 0,05900506 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02599558 0,05894945 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02599558 0,05889394 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02599558 0,05883854 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02599558 0,05878324 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02599558 0,05872804 ! protein targeting to ER GO:0045047 22 9 0,000 0,02599558 0,05867295 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02599558 0,05861796 ! T cell selection GO:0045058 23 9 0,000 0,02599558 0,05856308 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02599558 0,0585083 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02599558 0,05845361 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02599558 0,05839904 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02599558 0,05834456 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02599558 0,05829018 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02599558 0,05823591 ! mannose metabolic process GO:0006013 13 9 0,000 0,02599558 0,05818174 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02599558 0,05812767 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02599558 0,05807369 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02599558 0,05801982 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02599558 0,05796605 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02599558 0,05791238 ! ruffle organization GO:0031529 15 9 0,000 0,02599558 0,0578588 ! retinol metabolic process GO:0042572 18 9 0,000 0,02599558 0,05780533 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02599558 0,05775196 ! behavioral fear response GO:0001662 22 9 0,000 0,02599558 0,05769868 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02599558 0,0576455 GO:0007351|tripartite regional subdivision, ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02599558 0,05759242 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02599558 0,05753944 ! protein heterooligomerization GO:0051291 16 9 0,000 0,02599558 0,05748655 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02599558 0,05743376 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02599558 0,05738107 ! segment specification GO:0007379 13 9 0,000 0,02599558 0,05732848 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02599558 0,05727598 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02599558 0,05722358 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02599558 0,05717127 ! response to amine stimulus GO:0014075 13 9 0,000 0,02599558 0,05711906 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02599558 0,05706694 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02599558 0,05701492 ! erythrocyte development GO:0048821 15 9 0,000 0,02599558 0,05696299 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02599558 0,05691116 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02599558 0,05685943 ! renal water homeostasis GO:0003091 14 9 0,000 0,02599558 0,05680778 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02599558 0,05675623 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02599558 0,05670478 ! icosanoid secretion GO:0032309 15 9 0,000 0,02599558 0,05665341 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02599558 0,05660214 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02599558 0,05655097 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02599558 0,05649988 ! regulation of cell division GO:0051302 15 9 0,000 0,02599558 0,05644889 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02599558 0,05639799 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02599558 0,05634718 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02599558 0,05629646 ! sterol catabolic process GO:0016127 11 9 0,000 0,02599558 0,05624583 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02599558 0,0561953 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02599558 0,05614485 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02599558 0,0560945 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02599558 0,05604424 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02599558 0,05599406 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02599558 0,05594398 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02599558 0,05589398 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02599558 0,05584408 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02599558 0,05579426 ! purine base metabolic process GO:0006144 21 9 0,000 0,02599558 0,05574453 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02599558 0,0556949 ! pigment granule transport GO:0051904 17 9 0,000 0,02599558 0,05564534 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02599558 0,05559588 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02599558 0,05554651 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02599558 0,05549722 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02599558 0,05544802 ! mitochondrion localization GO:0051646 15 9 0,000 0,02599558 0,05539891 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,02689524 0,05726544 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,02689524 0,05721481 ! regulation of protein transport GO:0051223 154 87 1,000 0,02689524 0,05716426 GO:0070201|regulation of establishment of protein localization, ! ATP biosynthetic process GO:0006754 159 88 1,000 0,02746929 0,05833284 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,02804827 0,05950983 ! ossification GO:0001503 188 90 1,000 0,02863216 0,06069514 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,02863216 0,06064171 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,02863216 0,06058837 ! sex differentiation GO:0007548 145 90 1,000 0,02863216 0,06053513 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02884241 0,06092611 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02884241 0,06087267 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02884241 0,06081932 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02884241 0,06076606 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02884241 0,0607129 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02884241 0,06065983 ! synapsis GO:0007129 13 10 0,000 0,02884241 0,06060685 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02884241 0,06055396 ! N-glycan processing GO:0006491 20 10 0,000 0,02884241 0,06050117 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02884241 0,06044847 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02884241 0,06039586 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02884241 0,06034334 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02884241 0,06029092 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02884241 0,06023858 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02884241 0,06018633 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02884241 0,06013418 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02884241 0,06008212 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02884241 0,06003014 ! androgen metabolic process GO:0008209 17 10 0,000 0,02884241 0,05997826 ! phospholipid efflux GO:0033700 16 10 0,000 0,02884241 0,05992646 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02884241 0,05987476 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02884241 0,05982314 ! pathogenesis GO:0009405 13 10 0,000 0,02884241 0,05977161 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02884241 0,05972017 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02884241 0,05966882 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02884241 0,05961756 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02884241 0,05956639 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02884241 0,0595153 ! endoderm development GO:0007492 16 10 0,000 0,02884241 0,0594643 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02884241 0,05941339 ! arginine catabolic process GO:0006527 13 10 0,000 0,02884241 0,05936257 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02884241 0,05931183 ! proline metabolic process GO:0006560 13 10 0,000 0,02884241 0,05926118 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02884241 0,05921062 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02884241 0,05916014 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02884241 0,05910975 ! V(D)J recombination GO:0033151 28 10 0,000 0,02884241 0,05905944 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02884241 0,05900922 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02884241 0,05895909 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02884241 0,05890903 ! B cell proliferation GO:0042100 18 10 0,000 0,02884241 0,05885907 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02884241 0,05880919 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02884241 0,05875939 ! multicellular organism growth GO:0035264 18 10 0,000 0,02884241 0,05870968 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02884241 0,05866005 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02884241 0,05861051 ! epithelial cell development GO:0002064 20 10 0,000 0,02884241 0,05856105 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02884241 0,05851167 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02884241 0,05846238 ! macroautophagy GO:0016236 17 10 0,000 0,02884241 0,05841317 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02884241 0,05836404 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02884241 0,05831499 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02884241 0,05826603 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02884241 0,05821715 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02884241 0,05816835 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02884241 0,05811963 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02884241 0,058071 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02884241 0,05802244 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02884241 0,05797397 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02884241 0,05792558 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02884241 0,05787727 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02884241 0,05782904 ! response to dsRNA GO:0043331 20 10 0,000 0,02884241 0,05778089 ! DNA ligation GO:0006266 19 10 0,000 0,02884241 0,05773281 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02884241 0,05768482 ! melanosome localization GO:0032400 16 10 0,000 0,02884241 0,05763691 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02884241 0,05758908 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02884241 0,05754133 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02884241 0,05749366 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02884241 0,05744606 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02884241 0,05739855 ! mRNA cleavage GO:0006379 17 10 0,000 0,02884241 0,05735111 ! protein sumoylation GO:0016925 15 10 0,000 0,02884241 0,05730375 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02884241 0,05725647 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02884241 0,05720927 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02884241 0,05716214 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02884241 0,0571151 ! salivary gland development GO:0007431 27 10 0,000 0,02884241 0,05706813 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02884241 0,05702124 ! apical protein localization GO:0045176 15 10 0,000 0,02884241 0,05697442 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02884241 0,05692768 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 13 10 0,000 0,02884241 0,05688102 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02884241 0,05683443 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02884241 0,05678792 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02884241 0,05674149 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02884241 0,05669513 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02884241 0,05664885 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02884241 0,05660265 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02884241 0,05655651 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02884241 0,05651046 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02884241 0,05646448 ! oocyte development GO:0048599 17 10 0,000 0,02884241 0,05641857 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02884241 0,05637274 ! blastocyst formation GO:0001825 17 10 0,000 0,02884241 0,05632698 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02884241 0,0562813 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02884241 0,05623569 ! activation of innate immune response GO:0002218 12 10 0,000 0,02884241 0,05619016 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02884241 0,0561447 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02884241 0,05609931 ! response to nicotine GO:0035094 20 10 0,000 0,02884241 0,05605399 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02884241 0,05600875 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02884241 0,05596358 ! bone development GO:0060348 189 91 1,000 0,02922092 0,05665232 ! sterol metabolic process GO:0016125 152 91 1,000 0,02922092 0,0566067 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,03041291 0,05886843 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,03041291 0,05882111 ! regulation of membrane potential GO:0042391 164 93 1,000 0,03041291 0,05877386 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,03162398 0,06106525 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03168102 0,06112632 ! respiratory burst GO:0045730 17 11 0,000 0,03168102 0,06107734 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03168102 0,06102844 ! neuron fate specification GO:0048665 17 11 0,000 0,03168102 0,06097962 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03168102 0,06093088 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03168102 0,06088221 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03168102 0,06083362 ! thyroid gland development GO:0030878 26 11 0,000 0,03168102 0,06078511 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03168102 0,06073667 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03168102 0,06068832 ! response to pain GO:0048265 24 11 0,000 0,03168102 0,06064004 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03168102 0,06059183 ! T cell proliferation GO:0042098 26 11 0,000 0,03168102 0,06054371 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03168102 0,06049566 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,03168102 0,06044768 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03168102 0,06039978 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03168102 0,06035196 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03168102 0,06030421 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03168102 0,06025654 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03168102 0,06020895 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03168102 0,06016143 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03168102 0,06011398 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03168102 0,06006661 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03168102 0,06001931 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,03168102 0,05997209 ! lipid digestion GO:0044241 18 11 0,000 0,03168102 0,05992494 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03168102 0,05987787 ! UV protection GO:0009650 19 11 0,000 0,03168102 0,05983087 ! adult heart development GO:0007512 14 11 0,000 0,03168102 0,05978394 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03168102 0,05973709 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03168102 0,05969031 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03168102 0,0596436 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03168102 0,05959697 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03168102 0,05955041 ! regulation of organ growth GO:0046620 13 11 0,000 0,03168102 0,05950392 ! pigment granule localization GO:0051875 20 11 0,000 0,03168102 0,05945751 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03168102 0,05941117 ! vasoconstriction GO:0042310 18 11 0,000 0,03168102 0,0593649 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03168102 0,0593187 ! embryonic axis specification GO:0000578 18 11 0,000 0,03168102 0,05927257 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03168102 0,05922652 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03168102 0,05918053 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03168102 0,05913462 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03168102 0,05908878 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03168102 0,05904301 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03168102 0,05899731 ! zymogen activation GO:0031638 15 11 0,000 0,03168102 0,05895168 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03168102 0,05890613 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03168102 0,05886064 ! nucleosome positioning GO:0016584 15 11 0,000 0,03168102 0,05881522 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03168102 0,05876987 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03168102 0,0587246 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03168102 0,05867939 ! acid secretion GO:0046717 18 11 0,000 0,03168102 0,05863425 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03168102 0,05858918 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03168102 0,05854418 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03168102 0,05849925 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03168102 0,05845439 ! oocyte differentiation GO:0009994 18 11 0,000 0,03168102 0,0584096 ! thymus development GO:0048538 27 11 0,000 0,03168102 0,05836487 ! cholesterol efflux GO:0033344 19 11 0,000 0,03168102 0,05832022 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03168102 0,05827563 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03168102 0,05823111 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03168102 0,05818666 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03168102 0,05814228 ! embryonic gut development GO:0048566 15 11 0,000 0,03168102 0,05809796 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03168102 0,05805371 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03168102 0,05800953 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03168102 0,05796542 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03168102 0,05792137 ! defense response to fungus GO:0050832 13 11 0,000 0,03168102 0,05787739 ! developmental induction GO:0031128 19 11 0,000 0,03168102 0,05783348 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03168102 0,05778963 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03168102 0,05774585 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03168102 0,05770214 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03168102 0,05765849 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03168102 0,05761491 ! regulation of embryonic development GO:0045995 27 11 0,000 0,03168102 0,05757139 ! nucleus localization GO:0051647 19 11 0,000 0,03168102 0,05752794 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03168102 0,05748456 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,03285389 0,05956779 ! regulation of protein localization GO:0032880 176 97 1,000 0,03285389 0,05952294 ! response to virus GO:0009615 160 98 1,000 0,03347582 0,06060409 ! interphase GO:0051325 213 98 1,000 0,03347582 0,06055852 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,03410237 0,06164561 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03451142 0,06233819 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03451142 0,06229143 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03451142 0,06224473 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,03451142 0,06219811 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03451142 0,06215155 ! virus-host interaction GO:0019048 29 12 0,000 0,03451142 0,06210507 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,03451142 0,06205865 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03451142 0,0620123 ! cartilage condensation GO:0001502 20 12 0,000 0,03451142 0,06196602 ! mating GO:0007618 17 12 0,000 0,03451142 0,06191982 ! protein complex disassembly GO:0043241 27 12 0,000 0,03451142 0,06187368 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03451142 0,0618276 ! hippocampus development GO:0021766 26 12 0,000 0,03451142 0,0617816 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03451142 0,06173567 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03451142 0,0616898 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03451142 0,061644 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03451142 0,06159827 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03451142 0,06155261 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03451142 0,06150702 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03451142 0,06146149 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03451142 0,06141603 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03451142 0,06137064 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03451142 0,06132531 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03451142 0,06128005 ! focal adhesion formation GO:0048041 35 12 0,000 0,03451142 0,06123486 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03451142 0,06118974 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03451142 0,06114468 ! forebrain cell migration GO:0021885 21 12 0,000 0,03451142 0,06109969 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03451142 0,06105476 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03451142 0,0610099 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03451142 0,0609651 ! entry into host cell GO:0030260 32 12 0,000 0,03451142 0,06092038 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03451142 0,06087571 ! monoamine transport GO:0015844 18 12 0,000 0,03451142 0,06083112 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03451142 0,06078658 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03451142 0,06074212 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03451142 0,06069771 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03451142 0,06065338 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03451142 0,0606091 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03451142 0,0605649 ! protein homotetramerization GO:0051289 21 12 0,000 0,03451142 0,06052075 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03451142 0,06047667 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03451142 0,06043266 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03451142 0,06038871 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03451142 0,06034482 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03451142 0,060301 ! cranial nerve development GO:0021545 20 12 0,000 0,03451142 0,06025724 ! fucose catabolic process GO:0019317 22 12 0,000 0,03451142 0,06021354 GO:0042355|L-fucose catabolic process, ! histone methylation GO:0016571 26 12 0,000 0,03451142 0,06016991 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03451142 0,06012634 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03451142 0,06008283 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03451142 0,06003939 ! T cell homeostasis GO:0043029 25 12 0,000 0,03451142 0,05999601 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03451142 0,05995269 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03451142 0,05990943 ! spleen development GO:0048536 22 12 0,000 0,03451142 0,05986624 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03451142 0,05982311 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03451142 0,05978004 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03451142 0,05973703 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03451142 0,05969408 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,03451142 0,0596512 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03451142 0,05960838 ! response to cold GO:0009409 17 12 0,000 0,03451142 0,05956562 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03451142 0,05952292 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03451142 0,05948028 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03733364 0,06429831 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03733364 0,06425232 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03733364 0,06420639 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03733364 0,06416053 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03733364 0,06411473 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03733364 0,064069 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03733364 0,06402333 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03733364 0,06397773 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03733364 0,0639322 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03733364 0,06388673 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03733364 0,06384132 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03733364 0,06379598 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03733364 0,0637507 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03733364 0,06370549 ! methionine metabolic process GO:0006555 27 13 0,000 0,03733364 0,06366034 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03733364 0,06361525 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03733364 0,06357023 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03733364 0,06352527 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03733364 0,06348038 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03733364 0,06343555 ! response to X-ray GO:0010165 25 13 0,000 0,03733364 0,06339078 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03733364 0,06334608 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03733364 0,06330144 ! exocrine system development GO:0035272 32 13 0,000 0,03733364 0,06325686 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,03733364 0,06321234 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03733364 0,06316789 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03733364 0,0631235 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03733364 0,06307917 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03733364 0,0630349 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03733364 0,0629907 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03733364 0,06294656 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03733364 0,06290248 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03733364 0,06285846 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03733364 0,0628145 ! regulation of cellular pH GO:0030641 22 13 0,000 0,03733364 0,06277061 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03733364 0,06272677 ! ribosome assembly GO:0042255 17 13 0,000 0,03733364 0,062683 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03733364 0,06263929 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03733364 0,06259564 ! chromatin silencing GO:0006342 26 13 0,000 0,03733364 0,06255205 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03733364 0,06250852 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03733364 0,06246505 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03733364 0,06242164 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03733364 0,06237829 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03733364 0,062335 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03733364 0,06229177 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03733364 0,06224861 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03733364 0,0622055 ! embryonic placenta development GO:0001892 23 13 0,000 0,03733364 0,06216245 ! insulin secretion GO:0030073 23 13 0,000 0,03733364 0,06211946 ! actin filament polymerization GO:0030041 24 13 0,000 0,03733364 0,06207653 ! acrosome reaction GO:0007340 18 13 0,000 0,03733364 0,06203366 ! rRNA transcription GO:0009303 25 14 0,000 0,04014771 0,06666348 ! lactation GO:0007595 26 14 0,000 0,04014771 0,0666175 ! reproductive cellular process GO:0048610 20 14 0,000 0,04014771 0,06657159 ! tRNA modification GO:0006400 20 14 0,000 0,04014771 0,06652574 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04014771 0,06647996 ! regulation of S phase GO:0033261 23 14 0,000 0,04014771 0,06643424 ! water transport GO:0006833 21 14 0,000 0,04014771 0,06638858 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04014771 0,06634298 ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04014771 0,06629745 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04014771 0,06625198 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04014771 0,06620657 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04014771 0,06616122 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04014771 0,06611593 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04014771 0,06607071 ! palate development GO:0060021 31 14 0,000 0,04014771 0,06602555 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04014771 0,06598045 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04014771 0,06593541 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04014771 0,06589044 ! arginine metabolic process GO:0006525 17 14 0,000 0,04014771 0,06584552 ! regulation of heart rate GO:0002027 24 14 0,000 0,04014771 0,06580067 ! organic alcohol transport GO:0015850 29 14 0,000 0,04014771 0,06575588 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04014771 0,06571114 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04014771 0,06566647 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04014771 0,06562186 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04014771 0,06557731 ! L-amino acid transport GO:0015807 30 14 0,000 0,04014771 0,06553282 ! bone mineralization GO:0030282 17 14 0,000 0,04014771 0,06548839 ! stem cell development GO:0048864 43 14 0,000 0,04014771 0,06544402 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04014771 0,06539972 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04014771 0,06535547 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04014771 0,06531128 ! cerebellum development GO:0021549 21 14 0,000 0,04014771 0,06526715 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04014771 0,06522308 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04014771 0,06517907 ! response to gamma radiation GO:0010332 28 14 0,000 0,04014771 0,06513512 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04014771 0,06509123 ! cofactor transport GO:0051181 26 14 0,000 0,04014771 0,06504739 ! NADP metabolic process GO:0006739 24 14 0,000 0,04014771 0,06500362 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04014771 0,06495991 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04014771 0,06491625 ! intestinal absorption GO:0050892 25 14 0,000 0,04014771 0,06487265 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04014771 0,06482911 ! oxygen transport GO:0015671 21 14 0,000 0,04014771 0,06478563 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04014771 0,06474221 ! male genitalia development GO:0030539 24 14 0,000 0,04014771 0,06469885 ! regulation of axon extension GO:0030516 37 14 0,000 0,04014771 0,06465554 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,04014771 0,06461229 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04014771 0,0645691 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04295364 0,06903571 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04295364 0,06898962 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04295364 0,0689436 ! superoxide anion generation GO:0042554 20 15 0,000 0,04295364 0,06889764 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04295364 0,06885174 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04295364 0,0688059 ! copper ion transport GO:0006825 20 15 0,000 0,04295364 0,06876012 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04295364 0,0687144 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04295364 0,06866874 ! sulfate transport GO:0008272 23 15 0,000 0,04295364 0,06862314 ! response to cAMP GO:0051591 22 15 0,000 0,04295364 0,06857761 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04295364 0,06853213 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04295364 0,06848672 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04295364 0,06844136 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04295364 0,06839607 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04295364 0,06835083 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04295364 0,06830565 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04295364 0,06826054 ! pituitary gland development GO:0021983 29 15 0,000 0,04295364 0,06821548 ! vesicle coating GO:0006901 33 15 0,000 0,04295364 0,06817049 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04295364 0,06812555 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04295364 0,06808067 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,04295364 0,06803585 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04295364 0,06799109 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,04295364 0,06794639 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04295364 0,06790174 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04295364 0,06785716 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04295364 0,06781264 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04295364 0,06776817 ! histone deacetylation GO:0016575 20 15 0,000 0,04295364 0,06772376 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04295364 0,06767941 ! tissue regeneration GO:0042246 26 15 0,000 0,04295364 0,06763512 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04295364 0,06759088 ! water homeostasis GO:0030104 27 15 0,000 0,04295364 0,0675467 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04295364 0,06750258 ! muscle maintenance GO:0046716 26 15 0,000 0,04295364 0,06745852 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04295364 0,06741452 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04295364 0,06737057 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04295364 0,06732668 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04295364 0,06728285 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04295364 0,06723907 ! cell killing GO:0001906 29 15 0,000 0,04295364 0,06719535 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04295364 0,06715169 ! detection of bacterium GO:0016045 18 15 0,000 0,04295364 0,06710809 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04295364 0,06706454 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04295364 0,06702105 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04295364 0,06697761 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04295364 0,06693423 ! peptide hormone processing GO:0016486 23 15 0,000 0,04295364 0,06689091 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04575146 0,07120182 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,04575146 0,0711558 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04575146 0,07110983 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04575146 0,07106392 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04575146 0,07101808 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04575146 0,07097229 ! bone remodeling GO:0046849 27 16 0,000 0,04575146 0,07092656 ! filopodium assembly GO:0046847 32 16 0,000 0,04575146 0,07088089 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04575146 0,07083528 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04575146 0,07078972 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04575146 0,07074423 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04575146 0,07069879 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04575146 0,07065341 ! startle response GO:0001964 28 16 0,000 0,04575146 0,07060809 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04575146 0,07056283 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04575146 0,07051763 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04575146 0,07047248 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04575146 0,0704274 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04575146 0,07038236 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04575146 0,07033739 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04575146 0,07029248 ! response to osmotic stress GO:0006970 25 16 0,000 0,04575146 0,07024762 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04575146 0,07020282 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04575146 0,07015807 ! fructose metabolic process GO:0006000 25 16 0,000 0,04575146 0,07011339 ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04575146 0,07006876 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04575146 0,07002419 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04575146 0,06997967 ! axon cargo transport GO:0008088 43 16 0,000 0,04575146 0,06993521 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04575146 0,06989081 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04575146 0,06984646 ! DNA replication initiation GO:0006270 27 16 0,000 0,04575146 0,06980217 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04575146 0,06975793 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04575146 0,06971375 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04575146 0,06966963 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04575146 0,06962557 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04575146 0,06958155 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04575146 0,0695376 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04575146 0,0694937 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04575146 0,06944985 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04575146 0,06940606 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04575146 0,06936233 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,04575146 0,06931865 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04575146 0,06927503 ! defense response to virus GO:0051607 37 16 0,000 0,04575146 0,06923146 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0485412 0,07340674 ! metencephalon development GO:0022037 30 17 0,000 0,0485412 0,07336063 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,0485412 0,07331458 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0485412 0,07326859 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0485412 0,07322265 ! endothelial cell migration GO:0043542 28 17 0,000 0,0485412 0,07317677 ! inositol metabolic process GO:0006020 28 17 0,000 0,0485412 0,07313095 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0485412 0,07308519 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0485412 0,07303948 ! glial cell development GO:0021782 27 17 0,000 0,0485412 0,07299383 ! limbic system development GO:0021761 36 17 0,000 0,0485412 0,07294824 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0485412 0,0729027 ! adult walking behavior GO:0007628 33 17 0,000 0,0485412 0,07285722 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0485412 0,0728118 ! heart looping GO:0001947 30 17 0,000 0,0485412 0,07276643 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0485412 0,07272112 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,0485412 0,07267587 ! myoblast differentiation GO:0045445 45 17 0,000 0,0485412 0,07263068 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0485412 0,07258554 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,0485412 0,07254045 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0485412 0,07249542 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0485412 0,07245045 ! glycine metabolic process GO:0006544 28 17 0,000 0,0485412 0,07240553 ! NAD metabolic process GO:0019674 29 17 0,000 0,0485412 0,07236067 ! membrane budding GO:0006900 37 17 0,000 0,0485412 0,07231587 ! DNA integration GO:0015074 29 17 0,000 0,0485412 0,07227112 ! regulation of protein binding GO:0043393 33 17 0,000 0,0485412 0,07222642 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0485412 0,07218178 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0485412 0,0721372 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0485412 0,07209267 ! genitalia development GO:0048806 30 17 0,000 0,0485412 0,0720482 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,0485412 0,07200378 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0485412 0,07195941 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,0485412 0,0719151 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,0485412 0,07187085 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,0485412 0,07182665 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0485412 0,0717825 ! steroid catabolic process GO:0006706 31 17 0,000 0,0485412 0,07173841 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0485412 0,07169437 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,0485412 0,07165038 ! gas transport GO:0015669 25 17 0,000 0,0485412 0,07160645 ! organic cation transport GO:0015695 31 17 0,000 0,0485412 0,07156258 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0485412 0,07151875 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0485412 0,07147499 ! microspike assembly GO:0030035 36 17 0,000 0,0485412 0,07143127 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0485412 0,07138761 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,0485412 0,071344 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05132287 0,07538634 ! neuron maturation GO:0042551 42 18 0,000 0,05132287 0,07534035 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05132287 0,07529441 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05132287 0,07524853 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05132287 0,0752027 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05132287 0,07515693 ! memory GO:0007613 31 18 0,000 0,05132287 0,07511121 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05132287 0,07506555 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05132287 0,07501995 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05132287 0,0749744 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05132287 0,0749289 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,05132287 0,07488346 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05132287 0,07483808 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05132287 0,07479275 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05132287 0,07474748 ! response to retinoic acid GO:0032526 26 18 0,000 0,05132287 0,07470226 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05132287 0,07465709 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05132287 0,07461198 ! response to fungus GO:0009620 21 18 0,000 0,05132287 0,07456693 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05132287 0,07452193 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05132287 0,07447698 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05132287 0,07443209 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05132287 0,07438725 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05132287 0,07434246 ! vitamin transport GO:0051180 27 18 0,000 0,05132287 0,07429773 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05132287 0,07425306 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05132287 0,07420843 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05132287 0,07416386 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05132287 0,07411935 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,05132287 0,07407488 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05132287 0,07403048 ! nerve development GO:0021675 28 18 0,000 0,05132287 0,07398612 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05132287 0,07394182 ! protein secretion GO:0009306 39 19 0,000 0,05409651 0,0778912 ! positive regulation of translation GO:0045727 30 19 0,000 0,05409651 0,07784461 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05409651 0,07779808 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05409651 0,07775161 ! skin development GO:0043588 36 19 0,000 0,05409651 0,07770519 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05409651 0,07765883 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05409651 0,07761252 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05409651 0,07756627 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05409651 0,07752007 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05409651 0,07747393 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05409651 0,07742784 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,05409651 0,0773818 ! cerebral cortex development GO:0021987 36 19 0,000 0,05409651 0,07733583 ! pigmentation during development GO:0048066 41 19 0,000 0,05409651 0,0772899 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05409651 0,07724403 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05409651 0,07719822 ! heme metabolic process GO:0042168 36 19 0,000 0,05409651 0,07715246 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05409651 0,07710675 ! neuromuscular junction development GO:0007528 34 19 0,000 0,05409651 0,0770611 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05409651 0,0770155 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05409651 0,07696996 ! peptide cross-linking GO:0018149 37 19 0,000 0,05409651 0,07692446 ! protein export from nucleus GO:0006611 36 19 0,000 0,05409651 0,07687903 ! heart process GO:0003015 30 19 0,000 0,05409651 0,07683364 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05409651 0,07678832 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05409651 0,07674304 ! visual learning GO:0008542 36 19 0,000 0,05409651 0,07669782 ! cellular pigmentation GO:0033059 36 19 0,000 0,05409651 0,07665265 ! G1 phase GO:0051318 40 19 0,000 0,05409651 0,07660753 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05409651 0,07656247 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05409651 0,07651746 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05409651 0,0764725 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05409651 0,07642759 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05409651 0,07638274 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05409651 0,07633794 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05409651 0,0762932 ! cilium assembly GO:0042384 37 19 0,000 0,05409651 0,0762485 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05409651 0,07620386 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05686212 0,08005282 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05686212 0,080006 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05686212 0,07995924 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05686212 0,07991254 ! cAMP metabolic process GO:0046058 36 20 0,000 0,05686212 0,07986589 ! response to vitamin GO:0033273 31 20 0,000 0,05686212 0,07981929 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05686212 0,07977275 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,05686212 0,07972626 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05686212 0,07967983 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05686212 0,07963345 ! response to alkaloid GO:0043279 38 20 0,000 0,05686212 0,07958712 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05686212 0,07954085 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,05686212 0,07949463 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,05686212 0,07944847 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05686212 0,07940236 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05686212 0,0793563 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05686212 0,0793103 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,05686212 0,07926435 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05686212 0,07921845 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05686212 0,07917261 ! body fluid secretion GO:0007589 31 20 0,000 0,05686212 0,07912682 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05686212 0,07908108 ! peptide secretion GO:0002790 35 20 0,000 0,05686212 0,07903539 ! stem cell differentiation GO:0048863 53 20 0,000 0,05686212 0,07898976 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05686212 0,07894418 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05686212 0,07889865 ! diencephalon development GO:0021536 34 20 0,000 0,05686212 0,07885318 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05686212 0,07880776 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05686212 0,07876239 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05686212 0,07871707 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,05686212 0,0786718 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05686212 0,07862659 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05686212 0,07858143 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05686212 0,07853632 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05686212 0,07849126 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05686212 0,07844625 ! regulation of glucose import GO:0046324 29 20 0,000 0,05686212 0,0784013 GO:0010827|regulation of glucose transport, ! actin filament-based movement GO:0030048 43 20 0,000 0,05686212 0,0783564 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05686212 0,07831154 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,05686212 0,07826674 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05686212 0,07822199 ! negative regulation of translation GO:0017148 29 20 0,000 0,05686212 0,07817729 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05686212 0,07813265 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,05686212 0,07808805 ! regulation of cell killing GO:0031341 42 21 0,000 0,05961974 0,08182835 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05961974 0,0817817 ! hormone secretion GO:0046879 38 21 0,000 0,05961974 0,0817351 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05961974 0,08168856 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05961974 0,08164206 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05961974 0,08159562 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05961974 0,08154923 ! axis specification GO:0009798 38 21 0,000 0,05961974 0,0815029 ! ovarian follicle development GO:0001541 35 21 0,000 0,05961974 0,08145662 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05961974 0,08141039 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05961974 0,08136421 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05961974 0,08131809 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05961974 0,08127201 ! cell aging GO:0007569 44 21 0,000 0,05961974 0,08122599 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05961974 0,08118002 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05961974 0,08113411 ! cytolysis GO:0019835 24 21 0,000 0,05961974 0,08108824 ! vasodilation GO:0042311 39 21 0,000 0,05961974 0,08104243 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05961974 0,08099667 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05961974 0,08095096 ! DNA modification GO:0006304 34 21 0,000 0,05961974 0,0809053 ! collagen fibril organization GO:0030199 59 21 0,000 0,05961974 0,0808597 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05961974 0,08081414 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05961974 0,08076864 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,05961974 0,08072319 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05961974 0,08067779 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05961974 0,08063244 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05961974 0,08058714 ! collagen catabolic process GO:0030574 28 21 0,000 0,05961974 0,08054189 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05961974 0,08049669 ! gut development GO:0048565 39 21 0,000 0,05961974 0,08045154 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06236939 0,08411478 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06236939 0,08406765 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06236939 0,08402058 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06236939 0,08397357 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06236939 0,0839266 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06236939 0,08387969 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06236939 0,08383283 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06236939 0,08378602 ! keratinization GO:0031424 28 22 0,000 0,06236939 0,08373926 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06236939 0,08369256 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06236939 0,08364591 ! sensory perception of taste GO:0050909 28 22 0,000 0,06236939 0,08359931 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,06236939 0,08355276 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06236939 0,08350627 ! vacuolar transport GO:0007034 36 22 0,000 0,06236939 0,08345982 ! lysosome organization GO:0007040 41 22 0,000 0,06236939 0,08341343 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06236939 0,08336709 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06236939 0,0833208 ! fucose metabolic process GO:0006004 39 22 0,000 0,06236939 0,08327456 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06236939 0,08322838 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06236939 0,08318224 ! ureteric bud development GO:0001657 43 22 0,000 0,06236939 0,08313616 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06236939 0,08309012 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06236939 0,08304414 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06236939 0,08299821 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06236939 0,08295233 ! sarcomere organization GO:0045214 30 22 0,000 0,06236939 0,0829065 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,06236939 0,08286072 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06236939 0,08281499 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06236939 0,08276931 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06236939 0,08272368 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,06511109 0,08631256 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06511109 0,08626503 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,06511109 0,08621755 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06511109 0,08617013 ! gluconeogenesis GO:0006094 33 23 0,000 0,06511109 0,08612276 ! viral genome replication GO:0019079 41 23 0,000 0,06511109 0,08607544 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06511109 0,08602817 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06511109 0,08598095 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06511109 0,08593379 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06511109 0,08588667 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06511109 0,08583961 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06511109 0,0857926 ! visual behavior GO:0007632 42 23 0,000 0,06511109 0,08574565 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06511109 0,08569874 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,06511109 0,08565188 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06511109 0,08560508 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,06511109 0,08555833 ! peroxisome organization GO:0007031 37 23 0,000 0,06511109 0,08551162 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06511109 0,08546497 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06511109 0,08541837 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06511109 0,08537182 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06511109 0,08532532 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,06511109 0,08527888 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,06511109 0,08523248 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06511109 0,08518613 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06511109 0,08513983 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06511109 0,08509359 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06511109 0,08504739 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06511109 0,08500124 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06511109 0,08495515 ! fatty acid transport GO:0015908 44 23 0,000 0,06511109 0,0849091 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06511109 0,08486311 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06511109 0,08481716 ! hormone transport GO:0009914 40 23 0,000 0,06511109 0,08477126 ! cell-cell recognition GO:0009988 25 23 0,000 0,06511109 0,08472542 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06511109 0,08467962 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06511109 0,08463387 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06511109 0,08458817 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,06784487 0,08809215 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,06784487 0,08804464 ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,06784487 0,08799717 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,06784487 0,08794976 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06784487 0,0879024 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,06784487 0,08785509 ! spinal cord development GO:0021510 47 24 0,000 0,06784487 0,08780783 ! vacuole organization GO:0007033 43 24 0,000 0,06784487 0,08776062 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06784487 0,08771346 ! digestive system process GO:0022600 39 24 0,000 0,06784487 0,08766636 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06784487 0,0876193 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,06784487 0,08757229 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,06784487 0,08752534 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,06784487 0,08747843 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06784487 0,08743158 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,06784487 0,08738477 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,06784487 0,08733802 ! pallium development GO:0021543 49 24 0,000 0,06784487 0,08729131 ! pentose metabolic process GO:0019321 35 24 0,000 0,06784487 0,08724466 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06784487 0,08719805 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06784487 0,0871515 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06784487 0,08710499 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,06784487 0,08705854 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06784487 0,08701213 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,06784487 0,08696577 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06784487 0,08691947 ! regulation of amine transport GO:0051952 40 24 0,000 0,06784487 0,08687321 ! protein tetramerization GO:0051262 52 24 0,000 0,06784487 0,086827 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,07057074 0,09026752 ! myelination GO:0042552 45 25 0,000 0,07057074 0,09021956 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07057074 0,09017164 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07057074 0,09012378 ! phototransduction GO:0007602 33 25 0,000 0,07057074 0,09007597 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07057074 0,09002821 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,07057074 0,0899805 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,07057074 0,08993284 ! chromosome condensation GO:0030261 45 25 0,000 0,07057074 0,08988523 ! response to starvation GO:0042594 42 25 0,000 0,07057074 0,08983767 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07057074 0,08979017 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,07057074 0,08974271 ! neural crest cell development GO:0014032 54 25 0,000 0,07057074 0,0896953 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07057074 0,08964794 ! negative regulation of cell development GO:0010721 73 25 0,000 0,07057074 0,08960063 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,07057074 0,08955338 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07057074 0,08950617 ! interaction with host GO:0051701 62 25 0,000 0,07057074 0,08945901 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07057074 0,0894119 ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07057074 0,08936484 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07057074 0,08931783 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,07057074 0,08927087 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07057074 0,08922396 ! telomere organization GO:0032200 43 25 0,000 0,07057074 0,0891771 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07057074 0,08913029 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07057074 0,08908353 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07328873 0,09246601 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07328873 0,09241755 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07328873 0,09236914 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07328873 0,09232078 ! initiation of viral infection GO:0019059 57 26 0,000 0,07328873 0,09227247 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07328873 0,09222421 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07328873 0,092176 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07328873 0,09212784 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07328873 0,09207973 ! molting cycle process GO:0022404 50 26 0,000 0,07328873 0,09203167 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07328873 0,09198367 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07328873 0,09193571 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07328873 0,0918878 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,07328873 0,09183994 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,07328873 0,09179213 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,07328873 0,09174437 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,07328873 0,09169667 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07328873 0,09164901 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07328873 0,0916014 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07328873 0,09155384 ! blastocyst development GO:0001824 49 26 0,000 0,07328873 0,09150633 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07328873 0,09145886 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07328873 0,09141145 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07328873 0,09136409 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,07599886 0,09469356 ! neuron fate commitment GO:0048663 48 27 0,000 0,07599886 0,09464455 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,07599886 0,09459559 ! iron ion transport GO:0006826 59 27 0,000 0,07599886 0,09454667 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,07599886 0,09449781 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,07599886 0,094449 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,07599886 0,09440024 ! fat cell differentiation GO:0045444 50 27 0,000 0,07599886 0,09435153 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,07599886 0,09430287 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,07599886 0,09425426 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,07599886 0,0942057 ! autophagy GO:0006914 41 27 0,000 0,07599886 0,09415719 ! male gonad development GO:0008584 44 27 0,000 0,07599886 0,09410873 ! response to toxin GO:0009636 47 27 0,000 0,07599886 0,09406032 ! primary neural tube formation GO:0014020 51 27 0,000 0,07599886 0,09401196 ! base-excision repair GO:0006284 41 27 0,000 0,07599886 0,09396365 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,07599886 0,09391539 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,07599886 0,09386718 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,07599886 0,09381902 ! glutathione metabolic process GO:0006749 39 27 0,000 0,07599886 0,09377091 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,07599886 0,09372284 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,07599886 0,09367483 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,07599886 0,09362686 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,07599886 0,09357895 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,07870116 0,09685677 ! circadian rhythm GO:0007623 50 28 0,000 0,07870116 0,09680726 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,07870116 0,09675779 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,07870116 0,09670837 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,07870116 0,09665901 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,07870116 0,09660969 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,07870116 0,09656042 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,07870116 0,09651121 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,07870116 0,09646204 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,07870116 0,09641293 ! synaptogenesis GO:0007416 42 28 0,000 0,07870116 0,09636386 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,07870116 0,09631485 ! lipid oxidation GO:0034440 43 28 0,000 0,07870116 0,09626588 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,07870116 0,09621697 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,07870116 0,0961681 ! translational initiation GO:0006413 65 29 0,000 0,08139564 0,09941011 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,08139564 0,09935967 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08139564 0,09930929 ! regulation of pH GO:0006885 43 29 0,000 0,08139564 0,09925895 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,08139564 0,09920867 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08139564 0,09915844 ! catechol metabolic process GO:0009712 54 29 0,000 0,08139564 0,09910826 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08139564 0,09905813 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08139564 0,09900805 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08139564 0,09895802 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08139564 0,09890804 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08139564 0,09885811 ! cell fate determination GO:0001709 60 29 0,000 0,08139564 0,09880823 ! detection of light stimulus GO:0009583 38 29 0,000 0,08139564 0,09875841 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,08139564 0,09870863 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08139564 0,0986589 ! tissue homeostasis GO:0001894 48 29 0,000 0,08139564 0,09860922 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,08408234 0,10181283 ! zinc ion transport GO:0006829 45 30 0,000 0,08408234 0,10176162 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08408234 0,10171046 ! cell junction assembly GO:0034329 78 30 0,000 0,08408234 0,10165935 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08408234 0,10160829 ! myofibril assembly GO:0030239 47 30 0,000 0,08408234 0,10155728 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,08408234 0,10150632 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,08408234 0,10145542 ! phospholipid transport GO:0015914 51 30 0,000 0,08408234 0,10140456 ! ensheathment of neurons GO:0007272 57 30 0,000 0,08408234 0,10135376 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,08408234 0,101303 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08408234 0,1012523 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,08408234 0,10120165 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,08408234 0,10115105 ! eye morphogenesis GO:0048592 60 30 0,000 0,08408234 0,1011005 ! regulation of B cell activation GO:0050864 50 30 0,000 0,08408234 0,10105 ! response to heat GO:0009408 50 30 0,000 0,08408234 0,10099955 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,08676126 0,10416546 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,08676126 0,10411351 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,08676126 0,10406161 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,08676126 0,10400976 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,08676126 0,10395796 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,08676126 0,10390622 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,08676126 0,10385452 ! ovulation cycle process GO:0022602 49 31 0,000 0,08676126 0,10380288 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,08676126 0,10375129 ! peptide transport GO:0015833 55 31 0,000 0,08676126 0,10369975 ! iron ion homeostasis GO:0055072 54 31 0,000 0,08676126 0,10364826 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,08676126 0,10359682 ! mesoderm formation GO:0001707 69 31 0,000 0,08676126 0,10354543 ! natural killer cell activation GO:0030101 45 31 0,000 0,08676126 0,10349409 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,08676126 0,10344281 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,08676126 0,10339157 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,08676126 0,10334039 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,08676126 0,10328926 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,08943243 0,10641664 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,08943243 0,10636403 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,08943243 0,10631148 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,08943243 0,10625898 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,08943243 0,10620653 ! spliceosome assembly GO:0000245 67 32 0,000 0,08943243 0,10615414 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,08943243 0,10610179 ! metanephros development GO:0001656 74 32 0,000 0,08943243 0,1060495 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,08943243 0,10599726 ! response to ionizing radiation GO:0010212 65 32 0,000 0,08943243 0,10594507 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,08943243 0,10589293 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,08943243 0,10584084 ! muscle cell development GO:0055001 49 32 0,000 0,08943243 0,10578881 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,08943243 0,10573682 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,08943243 0,10568489 ! ovulation cycle GO:0042698 51 32 0,000 0,08943243 0,10563301 ! peripheral nervous system development GO:0007422 64 32 0,000 0,08943243 0,10558118 ! BMP signaling pathway GO:0030509 64 32 0,000 0,08943243 0,1055294 ! hindbrain development GO:0030902 61 32 0,000 0,08943243 0,10547767 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,08943243 0,10542599 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,08943243 0,10537436 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,08943243 0,10532278 ! gene silencing GO:0016458 65 32 0,000 0,08943243 0,10527125 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,09209589 0,1083534 ! post-embryonic development GO:0009791 69 33 0,000 0,09209589 0,10830044 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,09209589 0,10824753 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09209589 0,10819468 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,09209589 0,10814188 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09209589 0,10808912 ! formation of primary germ layer GO:0001704 72 33 0,000 0,09209589 0,10803642 ! cell fate specification GO:0001708 52 33 0,000 0,09209589 0,10798377 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,09209589 0,10793117 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09209589 0,10787863 ! adult locomotory behavior GO:0008344 59 33 0,000 0,09209589 0,10782613 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,09209589 0,10777369 ! glial cell differentiation GO:0010001 63 34 0,000 0,09475164 0,11082763 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,09475164 0,11077378 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,09475164 0,11071998 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,09475164 0,11066623 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,09475164 0,11061254 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,09475164 0,11055889 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,09475164 0,1105053 ! spermatid development GO:0007286 63 34 0,000 0,09475164 0,11045176 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,09475164 0,11039827 ! placenta development GO:0001890 53 34 0,000 0,09475164 0,11034484 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,09475164 0,11029145 ! regulation of muscle development GO:0048634 70 35 0,000 0,0973997 0,113319 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0973997 0,11326423 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0973997 0,11320951 ! odontogenesis GO:0042476 66 35 0,000 0,0973997 0,11315485 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0973997 0,11310024 ! female gonad development GO:0008585 58 35 0,000 0,0973997 0,11304568 ! telencephalon development GO:0021537 68 35 0,000 0,0973997 0,11299117 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,0973997 0,11293672 ! cytokine production GO:0001816 59 35 0,000 0,0973997 0,11288232 ! neural tube formation GO:0001841 67 35 0,000 0,0973997 0,11282797 ! vesicle localization GO:0051648 64 35 0,000 0,0973997 0,11277367 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,10004011 0,11577514 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10004011 0,11571948 ! cell junction organization GO:0034330 86 36 0,000 0,10004011 0,11566387 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10004011 0,11560832 ! positive regulation of cell development GO:0010720 80 36 0,000 0,10004011 0,11555282 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,10004011 0,11549737 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10004011 0,11544197 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10004011 0,11538663 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10004011 0,11533134 ! aerobic respiration GO:0009060 55 36 0,000 0,10004011 0,11527611 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,10004011 0,11522093 ! embryonic organ development GO:0048568 57 36 0,000 0,10004011 0,1151658 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10004011 0,11511072 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,10004011 0,1150557 ! RNA export from nucleus GO:0006405 56 37 0,000 0,10267289 0,11802722 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,10267289 0,11797085 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,10267289 0,11791454 ! sister chromatid segregation GO:0000819 58 37 0,000 0,10267289 0,11785829 ! actomyosin structure organization GO:0031032 62 37 0,000 0,10267289 0,11780208 ! organic anion transport GO:0015711 68 37 0,000 0,10267289 0,11774593 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,10267289 0,11768984 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,10267289 0,1176338 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,10267289 0,11757781 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,10267289 0,11752187 ! spermatid differentiation GO:0048515 66 37 0,000 0,10267289 0,11746599 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,10529805 0,12041212 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,10529805 0,12035492 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,10529805 0,12029777 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,10529805 0,12024068 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,10529805 0,12018364 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,10529805 0,12012665 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,10529805 0,12006972 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,10529805 0,12001284 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,10529805 0,11995601 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,10529805 0,11989924 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,10529805 0,11984253 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,10529805 0,11978586 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,10529805 0,11972925 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,10529805 0,1196727 ! learning GO:0007612 77 39 0,000 0,10791561 0,12258969 ! ear morphogenesis GO:0042471 60 39 0,000 0,10791561 0,12253184 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,10791561 0,12247404 ! ion transmembrane transport GO:0034220 66 39 0,000 0,10791561 0,1224163 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,10791561 0,12235861 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,10791561 0,12230097 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,10791561 0,12224339 ! RNA modification GO:0009451 57 39 0,000 0,10791561 0,12218587 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,10791561 0,12212839 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11052561 0,12502333 ! feeding behavior GO:0007631 59 40 0,000 0,11052561 0,12496457 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,11052561 0,12490588 ! mesenchymal cell development GO:0014031 87 40 0,000 0,11052561 0,12484724 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 0,000 0,11052561 0,12478865 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,11312805 0,12766703 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,11312805 0,12760717 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,11312805 0,12754737 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,11312805 0,12748763 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,11312805 0,12742795 ! T cell differentiation GO:0030217 81 41 0,000 0,11312805 0,12736832 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,11312805 0,12730875 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,11312805 0,12724923 ! polyol metabolic process GO:0019751 66 41 0,000 0,11312805 0,12718977 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,11312805 0,12713036 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,11572297 0,12998575 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,11572297 0,12992509 ! regulation of tube size GO:0035150 71 42 0,000 0,11572297 0,12986449 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,11572297 0,12980395 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,11572297 0,12974346 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,11572297 0,12968303 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,11572297 0,12962266 ! regulation of protein secretion GO:0050708 71 42 0,000 0,11572297 0,12956234 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,11831038 0,13239757 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,11831038 0,13233602 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,11831038 0,13227453 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,11831038 0,13221309 ! glucose transport GO:0015758 65 43 0,000 0,11831038 0,13215171 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,11831038 0,13209038 ! neural tube development GO:0021915 77 43 0,000 0,11831038 0,13202912 ! striated muscle contraction GO:0006941 77 43 0,000 0,11831038 0,13196791 ! phagocytosis GO:0006909 90 43 0,000 0,11831038 0,13190676 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,11831038 0,13184566 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,12089031 0,13465837 ! hexose transport GO:0008645 67 44 0,000 0,12089031 0,13459606 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,12089031 0,1345338 ! male sex differentiation GO:0046661 76 44 0,000 0,12089031 0,1344716 ! biopolymer methylation GO:0043414 84 44 0,000 0,12089031 0,13440946 ! B cell differentiation GO:0030183 107 44 0,000 0,12089031 0,13434738 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,12089031 0,13428536 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,12089031 0,13422339 ! developmental growth GO:0048589 82 44 0,000 0,12089031 0,13416148 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,12346277 0,13695317 ! glycolysis GO:0006096 65 45 0,000 0,12346277 0,13689006 ! leukocyte migration GO:0050900 68 45 0,000 0,12346277 0,136827 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,12346277 0,13676401 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,12346277 0,13670107 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,12346277 0,13663819 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,12346277 0,13657537 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,12346277 0,1365126 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,12346277 0,1364499 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,12602779 0,13922078 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,12602779 0,13915689 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,12602779 0,13909306 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,12602779 0,13902928 ! pigmentation GO:0043473 100 46 0,000 0,12602779 0,13896556 ! response to calcium ion GO:0051592 81 47 0,000 0,12858539 0,14172077 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,12858539 0,14165588 ! JNK cascade GO:0007254 91 47 0,000 0,12858539 0,14159105 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,12858539 0,14152628 ! methylation GO:0032259 90 47 0,000 0,12858539 0,14146157 ! mitochondrial transport GO:0006839 82 48 0,000 0,13113559 0,1442012 ! Notch signaling pathway GO:0007219 96 48 0,000 0,13113559 0,14413532 ! cellular component disassembly GO:0022411 86 48 0,000 0,13113559 0,14406951 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,13113559 0,14400375 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,13113559 0,14393806 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,13113559 0,14387242 ! activation of caspase activity GO:0006919 84 48 0,000 0,13113559 0,14380685 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,13113559 0,14374133 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,13113559 0,14367588 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,13367841 0,1463952 ! regulation of action potential GO:0001508 95 49 0,000 0,13367841 0,14632859 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,13367841 0,14626205 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,13367841 0,14619557 ! regulation of ion transport GO:0043269 77 49 0,000 0,13367841 0,14612915 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,13367841 0,14606278 ! peptide metabolic process GO:0006518 76 49 0,000 0,13367841 0,14599648 ! response to temperature stimulus GO:0009266 76 49 0,000 0,13367841 0,14593024 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,13367841 0,14586406 ! endocrine system development GO:0035270 104 49 0,000 0,13367841 0,14579794 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,13367841 0,14573188 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,13367841 0,14566587 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,13367841 0,14559993 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,13621387 0,14829438 ! neuromuscular process GO:0050905 99 50 0,000 0,13621387 0,14822731 ! inner ear development GO:0048839 79 50 0,000 0,13621387 0,1481603 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,13621387 0,14809335 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,13621387 0,14802646 ! viral infectious cycle GO:0019058 99 51 0,000 0,138742 0,15070575 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,138742 0,15063775 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,138742 0,1505698 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,138742 0,15050191 ! excretion GO:0007588 83 51 0,000 0,138742 0,15043409 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,138742 0,15036633 ! chromatin remodeling GO:0006338 109 51 0,000 0,138742 0,15029862 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,138742 0,15023098 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,138742 0,1501634 ! positive regulation of growth GO:0045927 90 52 0,000 0,14126281 0,15282298 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,14126281 0,1527543 ! cartilage development GO:0051216 90 52 0,000 0,14126281 0,15268568 ! synapse organization GO:0050808 85 52 0,000 0,14126281 0,15261712 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,14377632 0,15526294 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,14377632 0,15519329 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,14377632 0,15512369 ! cell maturation GO:0048469 100 53 0,000 0,14377632 0,15505416 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,14377632 0,15498469 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,14628257 0,1576157 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,14628257 0,15754515 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,14628257 0,15747466 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,14628257 0,15740423 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,14628257 0,15733387 ! chloride transport GO:0006821 90 55 0,000 0,14878156 0,15995015 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,14878156 0,15987871 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,14878156 0,15980733 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,14878156 0,15973602 ! aging GO:0007568 103 55 0,000 0,14878156 0,15966478 ! gastrulation GO:0007369 112 55 0,000 0,14878156 0,15959359 ! heart morphogenesis GO:0003007 97 55 0,000 0,14878156 0,15952247 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,14878156 0,15945142 ! RNA elongation GO:0006354 79 55 0,000 0,14878156 0,15938042 ! nuclear export GO:0051168 97 55 0,000 0,14878156 0,15930949 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,14878156 0,15923862 ! regulation of actin filament length GO:0030832 105 56 0,000 0,15127332 0,16183352 ! sensory perception of smell GO:0007608 80 56 0,000 0,15127332 0,1617616 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,15127332 0,16168974 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,15127332 0,16161794 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,15127332 0,1615462 ! regulation of DNA replication GO:0006275 101 56 0,000 0,15127332 0,16147453 ! proton transport GO:0015992 94 56 0,000 0,15127332 0,16140293 ! muscle fiber development GO:0048747 112 57 0,000 0,15375786 0,16398112 ! hydrogen transport GO:0006818 97 58 0,000 0,15623522 0,16654937 ! regulation of endocytosis GO:0030100 91 58 0,000 0,15623522 0,16647561 ! adult behavior GO:0030534 99 58 0,000 0,15623522 0,16640192 ! positive regulation of secretion GO:0051047 95 59 0,000 0,1587054 0,16895805 ! regulation of cellular component size GO:0032535 109 59 0,000 0,1587054 0,16888333 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,1587054 0,16880866 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,1587054 0,16873407 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,1587054 0,16865954 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,1587054 0,16858508 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,16116844 0,17112589 ! regulation of heart contraction GO:0008016 110 60 0,000 0,16116844 0,1710504 ! camera-type eye development GO:0043010 116 60 0,000 0,16116844 0,17097498 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,16116844 0,17089963 ! kidney development GO:0001822 122 60 0,000 0,16116844 0,17082434 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,16362434 0,17335102 ! mesoderm development GO:0007498 119 61 0,000 0,16362434 0,17327472 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,16362434 0,17319849 ! ear development GO:0043583 103 62 0,000 0,16607314 0,17571327 ! viral reproductive process GO:0022415 126 62 0,000 0,16607314 0,17563604 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,16607314 0,17555887 ! gonad development GO:0008406 98 62 0,000 0,16607314 0,17548177 ! detection of external stimulus GO:0009581 91 63 0,000 0,16851485 0,17798364 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,16851485 0,17790554 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,16851485 0,17782751 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,17094949 0,18031761 ! cell redox homeostasis GO:0045454 102 64 0,000 0,17094949 0,1802386 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,17094949 0,18015965 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,17094949 0,18008077 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,17337708 0,1825581 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,17337708 0,18247824 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,17337708 0,18239845 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,17337708 0,18231874 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,17579765 0,18478337 ! extracellular matrix organization GO:0030198 133 66 0,000 0,17579765 0,18470268 ! secondary metabolic process GO:0019748 116 66 0,000 0,17579765 0,18462206 ! developmental maturation GO:0021700 116 66 0,000 0,17579765 0,18454151 ! cell projection assembly GO:0030031 120 66 0,000 0,17579765 0,18446103 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,17821121 0,18691202 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,17821121 0,18683057 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,17821121 0,1867492 ! activation of MAPK activity GO:0000187 115 67 0,000 0,17821121 0,1866679 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,17821121 0,18658667 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,17821121 0,18650551 ! hexose catabolic process GO:0019320 104 67 0,000 0,17821121 0,18642442 ! activation of immune response GO:0002253 105 67 0,000 0,17821121 0,1863434 ! amino acid transport GO:0006865 125 68 0,000 0,18061778 0,18877775 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,18061778 0,18869577 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,18061778 0,18861388 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,18061778 0,18853205 ! viral reproduction GO:0016032 134 68 0,000 0,18061778 0,18845029 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,18061778 0,1883686 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,18061778 0,18828699 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,18301738 0,19070585 ! negative regulation of cell size GO:0045792 134 69 0,000 0,18301738 0,1906233 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,18301738 0,19054081 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,18301738 0,1904584 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,18301738 0,19037605 ! antigen processing and presentation GO:0019882 104 69 0,000 0,18301738 0,19029378 ! appendage morphogenesis GO:0035107 135 70 0,000 0,18541003 0,19269829 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,18779576 0,19509352 ! appendage development GO:0048736 136 71 0,000 0,18779576 0,19500932 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,18779576 0,19492519 ! regulation of immune effector process GO:0002697 137 71 0,000 0,18779576 0,19484114 ! regulation of caspase activity GO:0043281 122 72 0,000 0,19017458 0,19722415 ! carbohydrate transport GO:0008643 110 72 0,000 0,19017458 0,19713918 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,19017458 0,19705428 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,19017458 0,19696945 ! learning or memory GO:0007611 147 73 0,000 0,19254651 0,19934032 ! regulation of blood pressure GO:0008217 125 73 0,000 0,19254651 0,19925458 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,19254651 0,19916891 ! axon guidance GO:0007411 139 73 0,000 0,19254651 0,19908332 ! fertilization GO:0009566 90 73 0,000 0,19254651 0,19899781 ! transition metal ion transport GO:0000041 126 74 0,000 0,19491157 0,20135562 ! neurotransmitter transport GO:0006836 123 74 0,000 0,19491157 0,2012692 ! exocytosis GO:0006887 133 74 0,000 0,19491157 0,20118285 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,19491157 0,20109658 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,19491157 0,20101039 ! eye development GO:0001654 143 74 0,000 0,19491157 0,20092426 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,19726978 0,20326813 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,19726978 0,20318112 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,19726978 0,20309418 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,19726978 0,20300731 ! rhythmic process GO:0048511 128 75 0,000 0,19726978 0,20292052 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,19726978 0,2028338 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,19962116 0,20516383 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,19962116 0,20507623 ! defense response to bacterium GO:0042742 89 76 0,000 0,19962116 0,2049887 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,19962116 0,20490125 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,20196574 0,20721943 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,20196574 0,2071311 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,20196574 0,20704285 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,20430352 0,2093502 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,20430352 0,20926108 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,20430352 0,20917203 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,20663453 0,2114686 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,20663453 0,21137869 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,20663453 0,21128886 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,20663453 0,2111991 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,20663453 0,21110942 ! response to metal ion GO:0010038 140 80 0,000 0,2089588 0,2133934 ! muscle cell differentiation GO:0042692 159 80 0,000 0,2089588 0,21330287 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,2089588 0,21321241 ! inorganic anion transport GO:0015698 138 80 0,000 0,2089588 0,21312203 ! T cell activation GO:0042110 168 81 0,000 0,21127632 0,21539442 ! digestion GO:0007586 112 81 0,000 0,21127632 0,21530319 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,21127632 0,21521204 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,21127632 0,21512096 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,21127632 0,21502996 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,21358714 0,21728992 ! response to nutrient GO:0007584 125 82 0,000 0,21358714 0,21719808 ! negative regulation of growth GO:0045926 155 84 0,000 0,21818871 0,22178371 ! regulation of ligase activity GO:0051340 142 84 0,000 0,21818871 0,22169005 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,21818871 0,22159647 ! response to unfolded protein GO:0006986 131 85 0,000 0,22047951 0,22382856 ! nucleosome assembly GO:0006334 122 85 0,000 0,22047951 0,22373416 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,22047951 0,22363984 ! amine biosynthetic process GO:0009309 138 86 0,000 0,22276366 0,22586151 ! response to inorganic substance GO:0010035 153 86 0,000 0,22276366 0,22576637 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,22276366 0,22567131 ! chromatin assembly GO:0031497 124 86 0,000 0,22276366 0,22557634 ! tube morphogenesis GO:0035239 176 86 0,000 0,22276366 0,22548144 ! mitochondrion organization GO:0007005 148 86 0,000 0,22276366 0,22538662 ! alcohol catabolic process GO:0046164 130 86 0,000 0,22276366 0,22529188 ! amine transport GO:0015837 155 86 0,000 0,22276366 0,22519722 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,2250412 0,22740409 ! cellular respiration GO:0045333 135 88 0,000 0,22731214 0,22960244 ! regulation of neurological system process GO:0031644 148 88 0,000 0,22731214 0,22950609 ! cellular defense response GO:0006968 114 89 0,000 0,22957651 0,23169508 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,22957651 0,23159793 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,23183431 0,2337776 ! response to protein stimulus GO:0051789 149 91 0,000 0,23408557 0,23594884 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,23408557 0,23585003 ! nucleosome organization GO:0034728 138 92 0,000 0,2363303 0,23801202 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,2363303 0,23791243 ! vitamin metabolic process GO:0006766 139 92 0,000 0,2363303 0,23781293 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,23856854 0,23996484 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,23856854 0,23986456 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,24080028 0,2420073 ! female pregnancy GO:0007565 164 94 0,000 0,24080028 0,24190626 ! transcription initiation GO:0006352 153 94 0,000 0,24080028 0,24180529 ! forebrain development GO:0030900 188 95 0,000 0,24302556 0,24393805 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,24302556 0,24383632 ! leukocyte differentiation GO:0002521 202 96 0,000 0,2452444 0,24595999 ! mRNA transport GO:0051028 169 96 0,000 0,2452444 0,24585751 ! detection of stimulus GO:0051606 151 96 0,000 0,2452444 0,24575511 ! protein ubiquitination GO:0016567 217 97 0,000 0,2474568 0,24786888 ! hormone metabolic process GO:0042445 157 97 0,000 0,2474568 0,24776573 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,24966279 0,24987049 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,25186238 0,25196711 ! cell cycle arrest GO:0007050 213 100 0,000 0,2540556 0,2540556