pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/1001-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 2,000 8,755E-07 2,106E-03 ! protein sumoylation GO:0016925 15 10 2,000 1,249E-06 1,502E-03 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 2,000 1,249E-06 1,001E-03 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 2,000 1,714E-06 1,031E-03 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 2,000 1,714E-06 8,249E-04 ! regulation of interleukin-1 secretion GO:0050704 16 12 2,000 2,282E-06 9,151E-04 ! regulation of protein secretion GO:0050708 71 42 3,000 2,349E-06 8,074E-04 ! positive regulation of cytokine secretion GO:0050715 26 16 2,000 5,772E-06 1,736E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 6,998E-06 1,871E-03 ! positive regulation of caspase activity GO:0043280 95 55 3,000 7,003E-06 1,685E-03 GO:0010952|positive regulation of peptidase activity, ! regulation of DNA replication GO:0006275 101 56 3,000 7,53E-06 1,647E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 8,084E-06 1,621E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,168E-05 2,161E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 1,285E-05 2,209E-03 ! regulation of cytokine secretion GO:0050707 37 22 2,000 1,572E-05 2,522E-03 ! sex determination GO:0007530 47 23 2,000 1,805E-05 2,714E-03 ! regulation of caspase activity GO:0043281 122 72 3,000 2,053E-05 2,906E-03 ! protein tetramerization GO:0051262 52 24 2,000 2,06E-05 2,753E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 2,289E-05 2,899E-03 ! vasculogenesis GO:0001570 46 25 2,000 2,337E-05 2,811E-03 ! somitogenesis GO:0001756 43 25 2,000 2,337E-05 2,677E-03 ! positive regulation of protein secretion GO:0050714 36 25 2,000 2,337E-05 2,556E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 2,962E-05 3,099E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 2,964E-05 2,972E-03 ! negative regulation of protein kinase cascade GO:0010741 68 30 2,000 4,092E-05 3,939E-03 ! regulation of protein transport GO:0051223 154 87 3,000 4,333E-05 4,01E-03 GO:0070201|regulation of establishment of protein localization, ! negative regulation of bone resorption GO:0045779 10 5 1,000 4,854E-05 4,326E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 4,854E-05 4,171E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 4,854E-05 4,027E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 4,854E-05 3,893E-03 ! microvillus organization GO:0032528 7 5 1,000 4,854E-05 3,768E-03 GO:0030033|microvillus assembly, ! paraxial mesoderm development GO:0048339 14 5 1,000 4,854E-05 3,65E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,854E-05 3,539E-03 ! positive regulation of interleukin-4 production GO:0032753 8 5 1,000 4,854E-05 3,435E-03 GO:0032754|positive regulation of interleukin-5 production, ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 4,854E-05 3,337E-03 ! DNA damage checkpoint GO:0000077 71 33 2,000 5,473E-05 3,658E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 5,627E-05 3,659E-03 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 6,633E-05 4,2E-03 ! regulation of protein localization GO:0032880 176 97 3,000 6,633E-05 4,092E-03 ! DNA integrity checkpoint GO:0031570 75 36 2,000 7,129E-05 4,288E-03 ! male sex determination GO:0030238 15 6 1,000 7,271E-05 4,267E-03 ! regulation of interleukin-5 production GO:0032674 9 6 1,000 7,271E-05 4,165E-03 ! regulation of interleukin-13 production GO:0032656 11 6 1,000 7,271E-05 4,068E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 7,271E-05 3,976E-03 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 8,396E-05 4,489E-03 ! segmentation GO:0035282 67 39 2,000 9,081E-05 4,75E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 1,016E-04 5,204E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,016E-04 5,095E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,016E-04 4,991E-03 GO:0043489|RNA stabilization, ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 1,016E-04 4,891E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,016E-04 4,795E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,016E-04 4,703E-03 ! negative regulation of interferon-gamma production GO:0032689 12 7 1,000 1,016E-04 4,614E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,016E-04 4,529E-03 ! response to tumor cell GO:0002347 13 7 1,000 1,016E-04 4,447E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,016E-04 4,367E-03 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 1,016E-04 4,291E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,353E-04 5,614E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,353E-04 5,519E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,353E-04 5,427E-03 ! ER overload response GO:0006983 12 8 1,000 1,353E-04 5,338E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,353E-04 5,252E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,353E-04 5,169E-03 ! regulation of interleukin-4 production GO:0032673 17 8 1,000 1,353E-04 5,088E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,353E-04 5,01E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 1,492E-04 5,438E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,492E-04 5,357E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,694E-04 5,994E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 1,738E-04 6,059E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,738E-04 5,972E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 1,738E-04 5,888E-03 GO:0010469|regulation of receptor activity, ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,738E-04 5,806E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 1,738E-04 5,727E-03 ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 1,738E-04 5,649E-03 ! motor axon guidance GO:0008045 16 9 1,000 1,738E-04 5,574E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 1,738E-04 5,501E-03 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,738E-04 5,429E-03 ! regulation of cell shape GO:0008360 125 51 2,000 2,03E-04 6,262E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 2,169E-04 6,605E-03 ! lung alveolus development GO:0048286 26 10 1,000 2,169E-04 6,523E-03 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 2,169E-04 6,442E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,169E-04 6,364E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 2,169E-04 6,287E-03 ! apical protein localization GO:0045176 15 10 1,000 2,169E-04 6,212E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 2,169E-04 6,139E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,169E-04 6,068E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,169E-04 5,998E-03 ! localization within membrane GO:0051668 20 10 1,000 2,169E-04 5,93E-03 ! response to UV GO:0009411 104 53 2,000 2,276E-04 6,154E-03 ! negative regulation of muscle development GO:0048635 20 11 1,000 2,647E-04 7,076E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,647E-04 6,998E-03 ! blood vessel remodeling GO:0001974 29 11 1,000 2,647E-04 6,922E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 2,647E-04 6,848E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,647E-04 6,775E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 2,647E-04 6,704E-03 ! negative regulation of tumor necrosis factor production GO:0032720 15 11 1,000 2,647E-04 6,634E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 2,647E-04 6,566E-03 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 2,647E-04 6,499E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 2,647E-04 6,433E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 2,825E-04 6,798E-03 ! positive regulation of secretion GO:0051047 95 59 2,000 3,129E-04 7,454E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 3,172E-04 7,482E-03 ! virus-host interaction GO:0019048 29 12 1,000 3,172E-04 7,409E-03 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 3,172E-04 7,338E-03 GO:0050927|positive regulation of positive chemotaxis, ! hippocampus development GO:0021766 26 12 1,000 3,172E-04 7,268E-03 ! asymmetric protein localization GO:0008105 20 12 1,000 3,172E-04 7,199E-03 ! histone acetylation GO:0016573 26 12 1,000 3,172E-04 7,132E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,172E-04 7,066E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 3,172E-04 7,001E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 3,289E-04 7,193E-03 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 3,289E-04 7,128E-03 ! regulation of homeostatic process GO:0032844 134 62 2,000 3,623E-04 7,783E-03 ! response to X-ray GO:0010165 25 13 1,000 3,743E-04 7,97E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 3,743E-04 7,9E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 3,743E-04 7,831E-03 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,743E-04 7,764E-03 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 3,743E-04 7,697E-03 ! regulation of mRNA stability GO:0043488 31 13 1,000 3,743E-04 7,632E-03 ! regulation of mitosis GO:0007088 105 63 2,000 3,798E-04 7,679E-03 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 3,798E-04 7,615E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 4,361E-04 8,671E-03 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 4,361E-04 8,6E-03 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 4,361E-04 8,53E-03 ! response to gamma radiation GO:0010332 28 14 1,000 4,361E-04 8,461E-03 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 4,361E-04 8,393E-03 ! regulation of RNA stability GO:0043487 32 14 1,000 4,361E-04 8,327E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 4,361E-04 8,261E-03 ! activation of MAPK activity GO:0000187 115 67 2,000 4,553E-04 8,558E-03 ! lung development GO:0030324 144 67 2,000 4,553E-04 8,492E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 4,553E-04 8,427E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 4,756E-04 8,734E-03 ! cell cycle checkpoint GO:0000075 137 69 2,000 4,964E-04 9,048E-03 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 5,024E-04 9,089E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 5,024E-04 9,021E-03 ! G1/S transition checkpoint GO:0031575 40 15 1,000 5,024E-04 8,954E-03 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 5,024E-04 8,889E-03 ! respiratory tube development GO:0030323 150 70 2,000 5,178E-04 9,093E-03 ! respiratory system development GO:0060541 153 72 2,000 5,624E-04 9,804E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 5,734E-04 9,925E-03 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 5,734E-04 9,854E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 5,734E-04 9,784E-03 ! activation of MAPKK activity GO:0000186 35 16 1,000 5,734E-04 9,715E-03 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 5,734E-04 9,647E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 5,734E-04 9,58E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 5,734E-04 9,514E-03 ! limbic system development GO:0021761 36 17 1,000 6,489E-04 0,01069353 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 6,489E-04 0,01062079 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 6,489E-04 0,01054902 ! protein oligomerization GO:0051259 139 78 2,000 7,105E-04 0,01147345 ! response to retinoic acid GO:0032526 26 18 1,000 7,29E-04 0,01169261 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 7,29E-04 0,01161517 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 7,29E-04 0,01153876 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 7,374E-04 0,01159615 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 7,931E-04 0,01239074 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 2,000 7,931E-04 0,0123108 ! response to vitamin A GO:0033189 27 19 1,000 8,136E-04 0,01254755 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 8,136E-04 0,01246763 ! cellular pigmentation GO:0033059 36 19 1,000 8,136E-04 0,01238872 ! G1 phase GO:0051318 40 19 1,000 8,136E-04 0,0123108 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 8,136E-04 0,01223386 ! estrogen receptor signaling pathway GO:0030520 38 19 1,000 8,136E-04 0,01215787 ! response to oxygen levels GO:0070482 176 83 2,000 8,514E-04 0,01264448 ! protein amino acid acetylation GO:0006473 39 20 1,000 9,027E-04 0,01332385 ! response to vitamin GO:0033273 31 20 1,000 9,027E-04 0,0132426 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 9,027E-04 0,01316235 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 9,027E-04 0,01308305 ! cellular response to starvation GO:0009267 33 20 1,000 9,027E-04 0,01300471 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 9,027E-04 0,0129273 ! cell aging GO:0007569 44 21 1,000 9,962E-04 0,01418315 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 9,962E-04 0,01409972 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 9,962E-04 0,01401726 ! positive regulation of locomotion GO:0040017 39 21 1,000 9,962E-04 0,01393577 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of cell morphogenesis GO:0022604 215 89 2,000 1,042E-03 0,01449627 ! regulation of cell cycle process GO:0010564 149 90 2,000 1,077E-03 0,01488636 ! regulation of chemotaxis GO:0050920 40 22 1,000 1,094E-03 0,01504494 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 1,094E-03 0,01495946 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 1,094E-03 0,01487494 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 1,184E-03 0,01599747 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,197E-03 0,01608646 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 1,197E-03 0,01599709 ! negative regulation of cytokine production GO:0001818 40 23 1,000 1,197E-03 0,01590871 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 1,258E-03 0,01663592 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 1,304E-03 0,01714067 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,304E-03 0,01704751 ! regulation of behavior GO:0050795 43 24 1,000 1,304E-03 0,01695536 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 1,304E-03 0,01686421 ! regulation of tumor necrosis factor production GO:0032680 34 24 1,000 1,304E-03 0,01677402 ! pallium development GO:0021543 49 24 1,000 1,304E-03 0,0166848 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,304E-03 0,01659652 ! interphase GO:0051325 213 98 2,000 1,376E-03 0,01742757 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,415E-03 0,0178252 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 1,415E-03 0,01773236 ! negative regulation of DNA replication GO:0008156 42 25 1,000 1,415E-03 0,01764048 ! response to starvation GO:0042594 42 25 1,000 1,415E-03 0,01754955 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,415E-03 0,01745956 ! negative regulation of cell development GO:0010721 73 25 1,000 1,415E-03 0,01737048 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 1,415E-03 0,0172823 ! cellular response to nutrient levels GO:0031669 41 25 1,000 1,415E-03 0,01719502 ! regulation of interferon-gamma production GO:0032649 39 26 1,000 1,531E-03 0,01850775 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 1,531E-03 0,01841521 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 1,531E-03 0,0183236 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 1,531E-03 0,01823289 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 1,531E-03 0,01814307 ! response to estradiol stimulus GO:0032355 40 26 1,000 1,531E-03 0,01805413 ! positive regulation of nuclear division GO:0051785 40 26 1,000 1,531E-03 0,01796606 GO:0045840|positive regulation of mitosis, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 1,651E-03 0,01928148 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 1,651E-03 0,01918833 ! protein amino acid acylation GO:0043543 55 27 1,000 1,651E-03 0,01909608 ! mitochondrial membrane organization GO:0007006 57 27 1,000 1,651E-03 0,01900471 ! autophagy GO:0006914 41 27 1,000 1,651E-03 0,01891421 ! male gonad development GO:0008584 44 27 1,000 1,651E-03 0,01882457 ! base-excision repair GO:0006284 41 27 1,000 1,651E-03 0,01873577 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,775E-03 0,02005348 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 1,775E-03 0,01995977 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 1,775E-03 0,01986693 ! regulation of pH GO:0006885 43 29 1,000 1,904E-03 0,02120933 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 1,904E-03 0,02111159 ! mesoderm formation GO:0001707 69 31 1,000 2,175E-03 0,0239997 ! metanephros development GO:0001656 74 32 1,000 2,316E-03 0,02544628 ! response to ionizing radiation GO:0010212 65 32 1,000 2,316E-03 0,02533062 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 2,316E-03 0,025216 ! positive regulation of catabolic process GO:0009896 64 32 1,000 2,316E-03 0,02510241 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 2,462E-03 0,02656399 ! formation of primary germ layer GO:0001704 72 33 1,000 2,462E-03 0,0264454 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 2,612E-03 0,0279333 ! mesoderm morphogenesis GO:0048332 76 34 1,000 2,612E-03 0,02780971 ! placenta development GO:0001890 53 34 1,000 2,612E-03 0,0276872 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 2,612E-03 0,02756576 ! regulation of muscle development GO:0048634 70 35 1,000 2,767E-03 0,02906707 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 2,767E-03 0,02894069 ! negative regulation of secretion GO:0051048 63 35 1,000 2,767E-03 0,0288154 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 2,767E-03 0,0286912 ! odontogenesis GO:0042476 66 35 1,000 2,767E-03 0,02856806 ! telencephalon development GO:0021537 68 35 1,000 2,767E-03 0,02844598 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 2,767E-03 0,02832493 ! calcium-mediated signaling GO:0019722 62 35 1,000 2,767E-03 0,02820491 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 2,925E-03 0,02969544 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 2,925E-03 0,02957067 ! tissue remodeling GO:0048771 76 37 1,000 3,088E-03 0,03108507 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 3,088E-03 0,03095555 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 3,088E-03 0,03082711 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 3,255E-03 0,03235889 ! carbohydrate homeostasis GO:0033500 53 38 1,000 3,255E-03 0,03222572 GO:0042593|glucose homeostasis, ! mammary gland development GO:0030879 86 39 1,000 3,426E-03 0,03378004 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 3,426E-03 0,03364216 ! T cell differentiation GO:0030217 81 41 1,000 3,78E-03 0,0369715 ! regulation of T cell differentiation GO:0045580 70 41 1,000 3,78E-03 0,03682182 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 3,963E-03 0,03845194 GO:0090047|positive regulation of transcription regulator activity, ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 3,963E-03 0,03829752 ! epithelial cell differentiation GO:0030855 79 43 1,000 4,151E-03 0,03994782 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 4,151E-03 0,03978867 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 4,151E-03 0,03963078 ! male sex differentiation GO:0046661 76 44 1,000 4,342E-03 0,04129473 ! double-strand break repair GO:0006302 81 44 1,000 4,342E-03 0,04113215 ! B cell differentiation GO:0030183 107 44 1,000 4,342E-03 0,04097085 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 4,342E-03 0,04081081 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 4,538E-03 0,04248199 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 4,538E-03 0,04231733 ! cell growth GO:0016049 84 45 1,000 4,538E-03 0,04215394 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 4,737E-03 0,04383779 ! pigmentation GO:0043473 100 46 1,000 4,737E-03 0,04366983 ! response to insulin stimulus GO:0032868 95 46 1,000 4,737E-03 0,04350315 ! positive regulation of DNA binding GO:0043388 73 47 1,000 4,941E-03 0,04519918 ! vascular process in circulatory system GO:0003018 80 47 1,000 4,941E-03 0,04502797 ! regulation of adaptive immune response GO:0002819 84 47 1,000 4,941E-03 0,04485805 ! mitochondrial transport GO:0006839 82 48 1,000 5,148E-03 0,0465658 ! activation of caspase activity GO:0006919 84 48 1,000 5,148E-03 0,0463914 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 5,148E-03 0,0462183 ! histone modification GO:0016570 91 50 1,000 5,575E-03 0,04986339 ! positive regulation of cytokine production GO:0001819 86 50 1,000 5,575E-03 0,04967871 ! positive regulation of binding GO:0051099 78 51 1,000 5,794E-03 0,05144205 ! response to estrogen stimulus GO:0043627 93 51 1,000 5,794E-03 0,05125292 ! positive regulation of growth GO:0045927 90 52 1,000 6,017E-03 0,05303196 ! covalent chromatin modification GO:0016569 101 52 1,000 6,017E-03 0,05283841 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 6,017E-03 0,05264627 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 6,244E-03 0,05443478 ! activation of phospholipase C activity GO:0007202 103 54 1,000 6,475E-03 0,05624396 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 6,71E-03 0,05807342 ! aging GO:0007568 103 55 1,000 6,71E-03 0,05786527 ! gastrulation GO:0007369 112 55 1,000 6,71E-03 0,05765861 ! heart morphogenesis GO:0003007 97 55 1,000 6,71E-03 0,05745342 ! nucleotide-excision repair GO:0006289 83 56 1,000 6,949E-03 0,05928532 ! positive regulation of organelle organization GO:0010638 100 56 1,000 6,949E-03 0,05907584 ! regulation of bone remodeling GO:0046850 137 57 1,000 7,191E-03 0,06092143 ! regulation of phospholipase activity GO:0010517 106 57 1,000 7,191E-03 0,06070767 ! regulation of tissue remodeling GO:0034103 140 58 1,000 7,437E-03 0,06256658 ! positive regulation of lipase activity GO:0060193 108 58 1,000 7,437E-03 0,06234857 ! camera-type eye development GO:0043010 116 60 1,000 7,941E-03 0,06634019 ! kidney development GO:0001822 122 60 1,000 7,941E-03 0,06611064 ! mesoderm development GO:0007498 119 61 1,000 8,198E-03 0,06801887 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 8,198E-03 0,06778512 ! viral reproductive process GO:0022415 126 62 1,000 8,46E-03 0,06970524 ! gonad development GO:0008406 98 62 1,000 8,46E-03 0,06946734 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 9,265E-03 0,07582539 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 9,265E-03 0,07556836 ! cell projection assembly GO:0030031 120 66 1,000 9,541E-03 0,07755594 ! negative regulation of cell growth GO:0030308 132 67 1,000 9,821E-03 0,07955962 ! positive regulation of T cell activation GO:0050870 109 67 1,000 9,821E-03 0,07929265 ! adaptive immune response GO:0002250 119 67 1,000 9,821E-03 0,07902745 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! viral reproduction GO:0016032 134 68 1,000 0,01010414 0,08103524 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01010414 0,08076602 ! negative regulation of cell size GO:0045792 134 69 1,000 0,01039094 0,08278348 ! urogenital system development GO:0001655 137 69 1,000 0,01039094 0,08251027 ! appendage morphogenesis GO:0035107 135 70 1,000 0,01068133 0,08453711 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 1,000 0,01097529 0,08657884 ! appendage development GO:0048736 136 71 1,000 0,01097529 0,0862959 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 1,000 0,01097529 0,0860148 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01107464 0,08651161 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01107464 0,08623164 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01107464 0,08595347 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01107464 0,0856771 ! neuron fate determination GO:0048664 7 5 0,000 0,01107464 0,08540249 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01107464 0,08512964 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01107464 0,08485852 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01107464 0,08458913 ! polyol transport GO:0015791 12 5 0,000 0,01107464 0,08432145 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01107464 0,08405545 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01107464 0,08379112 ! response to superoxide GO:0000303 10 5 0,000 0,01107464 0,08352845 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01107464 0,08326743 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01107464 0,08300803 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01107464 0,08275024 ! female meiosis GO:0007143 7 5 0,000 0,01107464 0,08249405 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01107464 0,08223943 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01107464 0,08198639 ! cobalt ion transport GO:0006824 11 5 0,000 0,01107464 0,0817349 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01107464 0,08148494 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01107464 0,08123651 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01107464 0,08098959 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01107464 0,08074417 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01107464 0,08050023 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01107464 0,08025776 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01107464 0,08001675 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01107464 0,07977718 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01107464 0,07953903 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01107464 0,07930231 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01107464 0,07906699 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01107464 0,07883307 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01107464 0,07860052 ! negative chemotaxis GO:0050919 14 5 0,000 0,01107464 0,07836934 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01107464 0,07813952 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01107464 0,07791104 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01107464 0,0776839 ! behavioral response to pain GO:0048266 9 5 0,000 0,01107464 0,07745807 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01107464 0,07723356 ! Notch receptor processing GO:0007220 8 5 0,000 0,01107464 0,07701034 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01107464 0,07678841 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01107464 0,07656775 ! micturition GO:0060073 9 5 0,000 0,01107464 0,07634836 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01107464 0,07613022 ! copulation GO:0007620 9 5 0,000 0,01107464 0,07591332 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01107464 0,07569766 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01107464 0,07548322 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01107464 0,07526999 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01107464 0,07505796 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01107464 0,07484713 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01107464 0,07463747 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01107464 0,07442899 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01107464 0,07422166 ! grooming behavior GO:0007625 6 5 0,000 0,01107464 0,07401549 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01107464 0,07381046 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01107464 0,07360657 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01107464 0,07340379 ! response to protozoan GO:0001562 10 5 0,000 0,01107464 0,07320213 ! lymph vessel development GO:0001945 10 5 0,000 0,01107464 0,07300158 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01107464 0,07280212 ! endochondral ossification GO:0001958 16 5 0,000 0,01107464 0,07260375 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01107464 0,07240646 ! parathyroid gland development GO:0060017 13 5 0,000 0,01107464 0,07221023 ! anagen GO:0042640 6 5 0,000 0,01107464 0,07201507 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01107464 0,07182096 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01107464 0,07162789 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01107464 0,07143586 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01107464 0,07124486 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01107464 0,07105487 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01107464 0,0708659 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01107464 0,07067792 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01107464 0,07049094 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01107464 0,07030495 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01107464 0,07011994 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01107464 0,0699359 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01107464 0,06975282 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01107464 0,0695707 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01107464 0,06938952 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01107464 0,06920929 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01107464 0,06902999 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01107464 0,06885162 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01107464 0,06867417 ! histidine catabolic process GO:0006548 6 5 0,000 0,01107464 0,06849763 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01107464 0,06832199 ! valine metabolic process GO:0006573 10 5 0,000 0,01107464 0,06814725 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01107464 0,06797341 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01107464 0,06780045 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01107464 0,06762837 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01107464 0,06745716 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01107464 0,06728681 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01107464 0,06711732 ! polyol catabolic process GO:0046174 7 5 0,000 0,01107464 0,06694869 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01107464 0,06678089 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01107464 0,06661394 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01107464 0,06644782 ! muscle cell migration GO:0014812 8 5 0,000 0,01107464 0,06628253 ! mitochondrial fission GO:0000266 8 5 0,000 0,01107464 0,06611806 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01107464 0,0659544 ! mRNA transcription GO:0009299 9 5 0,000 0,01107464 0,06579155 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01107464 0,0656295 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01107464 0,06546825 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01107464 0,06530779 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01107464 0,06514811 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01107464 0,06498921 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01107464 0,06483109 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01107464 0,06467373 ! response to food GO:0032094 6 5 0,000 0,01107464 0,06451713 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01107464 0,0643613 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01107464 0,06420621 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01107464 0,06405187 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01107464 0,06389827 ! forebrain neuron development GO:0021884 13 5 0,000 0,01107464 0,0637454 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01107464 0,06359326 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01107464 0,06344185 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01107464 0,06329116 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01107464 0,06314118 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01107464 0,06299191 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01107464 0,06284334 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01107464 0,06269547 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01107464 0,0625483 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01107464 0,06240182 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01107464 0,06225602 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01107464 0,0621109 ! basic amino acid transport GO:0015802 11 5 0,000 0,01107464 0,06196646 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01107464 0,06182268 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01107464 0,06167958 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01107464 0,06153713 ! depyrimidination GO:0045008 10 5 0,000 0,01107464 0,06139534 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01107464 0,0612542 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01107464 0,06111371 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01107464 0,06097386 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01107464 0,06083465 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01107464 0,06069607 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01107464 0,06055813 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01107464 0,06042081 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01107464 0,06028411 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01107464 0,06014803 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01107464 0,06001256 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01107464 0,0598777 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01107464 0,05974345 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01107464 0,05960979 ! response to arsenic GO:0046685 10 5 0,000 0,01107464 0,05947673 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01107464 0,05934427 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01107464 0,05921239 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01107464 0,0590811 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01107464 0,05895039 ! response to cadmium ion GO:0046686 7 5 0,000 0,01107464 0,05882026 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01107464 0,0586907 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01107464 0,05856171 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01107464 0,05843328 ! decidualization GO:0046697 11 5 0,000 0,01107464 0,05830542 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01107464 0,05817812 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01107464 0,05805137 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01107464 0,05792517 ! protein autoprocessing GO:0016540 7 5 0,000 0,01107464 0,05779952 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01107464 0,05767441 ! neural tube patterning GO:0021532 7 5 0,000 0,01107464 0,05754984 ! embryonic cleavage GO:0040016 6 5 0,000 0,01107464 0,05742581 ! peroxisome fission GO:0016559 5 5 0,000 0,01107464 0,05730232 ! histone demethylation GO:0016577 10 5 0,000 0,01107464 0,05717935 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01107464 0,05705691 ! mitotic recombination GO:0006312 9 5 0,000 0,01107464 0,05693499 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01107464 0,0568136 ! metaphase plate congression GO:0051310 7 5 0,000 0,01107464 0,05669272 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01107464 0,05657235 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01107464 0,05645249 ! enteric nervous system development GO:0048484 8 5 0,000 0,01107464 0,05633314 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01107464 0,0562143 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01107464 0,05609595 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01107464 0,0559781 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01107464 0,05586075 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01107464 0,05574388 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01107464 0,05562751 ! plasminogen activation GO:0031639 5 5 0,000 0,01107464 0,05551162 ! B cell homeostasis GO:0001782 13 5 0,000 0,01107464 0,05539621 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01107464 0,05528128 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01107464 0,05516683 ! metaphase GO:0051323 8 5 0,000 0,01107464 0,05505284 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01107464 0,05493933 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01107464 0,05482629 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01107464 0,05471371 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01107464 0,05460159 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01107464 0,05448993 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01107464 0,05437873 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01107464 0,05426798 ! response to redox state GO:0051775 5 5 0,000 0,01107464 0,05415768 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01107464 0,05404782 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01107464 0,05393841 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01107464 0,05382945 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01107464 0,05372092 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01107464 0,05361283 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01107464 0,05350517 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01107464 0,05339795 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01107464 0,05329115 ! striatum development GO:0021756 9 5 0,000 0,01107464 0,05318478 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01107464 0,05307884 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01107464 0,05297331 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01107464 0,05286821 ! glial cell migration GO:0008347 11 5 0,000 0,01107464 0,05276352 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01107464 0,05265924 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01107464 0,05255538 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01107464 0,05245192 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01107464 0,05234887 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01107464 0,05224623 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01107464 0,05214399 ! neuroprotection GO:0043526 6 5 0,000 0,01107464 0,05204214 ! neural plate development GO:0001840 8 5 0,000 0,01107464 0,0519407 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01107464 0,05183964 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01107464 0,05173898 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01107464 0,05163871 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01107464 0,05153883 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01107464 0,05143934 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01107464 0,05134022 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01107464 0,05124149 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01107464 0,05114314 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01107464 0,05104517 ! spindle assembly GO:0051225 6 5 0,000 0,01107464 0,05094757 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01107464 0,05085034 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01107464 0,05075348 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01107464 0,05065699 ! drug metabolic process GO:0017144 6 5 0,000 0,01107464 0,05056087 ! stem cell division GO:0017145 11 5 0,000 0,01107464 0,05046511 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01107464 0,05036971 ! organ regeneration GO:0031100 7 5 0,000 0,01107464 0,05027467 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01107464 0,05017999 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01107464 0,05008567 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01107464 0,0499917 ! axon guidance GO:0007411 139 73 1,000 0,01157385 0,05214735 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01187842 0,0534196 GO:0090046|regulation of transcription regulator activity, ! eye development GO:0001654 143 74 1,000 0,01187842 0,05331993 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,0121865 0,05460096 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,01249806 0,05589281 ! regulation of catabolic process GO:0009894 161 76 1,000 0,01249806 0,05578912 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01281309 0,05708945 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,01313158 0,05840035 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01327502 0,05892934 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01327502 0,05882082 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01327502 0,05871269 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01327502 0,05860496 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01327502 0,05849763 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01327502 0,05839068 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01327502 0,05828413 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01327502 0,05817797 ! sleep GO:0030431 13 6 0,000 0,01327502 0,05807219 ! response to oxygen radical GO:0000305 11 6 0,000 0,01327502 0,05796679 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01327502 0,05786178 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01327502 0,05775715 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01327502 0,05765289 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01327502 0,05754902 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01327502 0,05744551 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01327502 0,05734238 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01327502 0,05723961 ! forebrain regionalization GO:0021871 8 6 0,000 0,01327502 0,05713722 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01327502 0,05703518 ! male meiosis GO:0007140 7 6 0,000 0,01327502 0,05693352 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01327502 0,05683221 ! response to zinc ion GO:0010043 9 6 0,000 0,01327502 0,05673127 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01327502 0,05663068 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01327502 0,05653045 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01327502 0,05643057 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01327502 0,05633105 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01327502 0,05623187 ! malate metabolic process GO:0006108 11 6 0,000 0,01327502 0,05613305 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01327502 0,05603457 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01327502 0,05593643 ! protein refolding GO:0042026 15 6 0,000 0,01327502 0,05583864 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01327502 0,05574119 ! opsonization GO:0008228 8 6 0,000 0,01327502 0,05564408 ! mating behavior GO:0007617 7 6 0,000 0,01327502 0,05554731 ! neuron remodeling GO:0016322 15 6 0,000 0,01327502 0,05545087 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01327502 0,05535477 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01327502 0,055259 ! equilibrioception GO:0050957 14 6 0,000 0,01327502 0,05516356 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01327502 0,05506845 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01327502 0,05497367 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01327502 0,05487922 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01327502 0,05478508 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01327502 0,05469127 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01327502 0,05459778 ! toxin metabolic process GO:0009404 11 6 0,000 0,01327502 0,05450461 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01327502 0,05441176 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01327502 0,05431922 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01327502 0,054227 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01327502 0,05413509 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01327502 0,05404349 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01327502 0,0539522 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01327502 0,05386122 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01327502 0,05377054 ! thymic T cell selection GO:0045061 12 6 0,000 0,01327502 0,05368017 ! protein lipoylation GO:0009249 10 6 0,000 0,01327502 0,05359011 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01327502 0,05350034 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01327502 0,05341088 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01327502 0,05332171 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01327502 0,05323284 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01327502 0,05314427 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01327502 0,05305599 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01327502 0,052968 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01327502 0,0528803 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01327502 0,0527929 ! hyperosmotic response GO:0006972 9 6 0,000 0,01327502 0,05270578 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01327502 0,05261895 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01327502 0,05253241 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01327502 0,05244615 ! urea metabolic process GO:0019627 7 6 0,000 0,01327502 0,05236017 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01327502 0,05227447 ! neutrophil activation GO:0042119 8 6 0,000 0,01327502 0,05218906 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01327502 0,05210392 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01327502 0,05201906 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01327502 0,05193448 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01327502 0,05185017 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01327502 0,05176613 ! neuron apoptosis GO:0051402 9 6 0,000 0,01327502 0,05168237 ! nucleoside salvage GO:0043174 9 6 0,000 0,01327502 0,05159887 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01327502 0,05151565 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01327502 0,05143269 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01327502 0,05135001 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01327502 0,05126758 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01327502 0,05118542 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01327502 0,05110353 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01327502 0,05102189 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01327502 0,05094052 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01327502 0,0508594 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01327502 0,05077854 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01327502 0,05069794 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01327502 0,0506176 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01327502 0,05053751 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01327502 0,05045767 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01327502 0,05037808 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01327502 0,05029875 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01327502 0,05021966 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01327502 0,05014082 ! neural nucleus development GO:0048857 14 6 0,000 0,01327502 0,05006223 ! response to UV-C GO:0010225 11 6 0,000 0,01327502 0,04998389 ! astrocyte development GO:0014002 15 6 0,000 0,01327502 0,04990579 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01327502 0,04982793 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01327502 0,04975032 ! interaction with symbiont GO:0051702 13 6 0,000 0,01327502 0,04967294 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01327502 0,04959581 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01327502 0,04951892 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01327502 0,04944227 ! response to copper ion GO:0046688 10 6 0,000 0,01327502 0,04936585 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01327502 0,04928967 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01327502 0,04921372 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01327502 0,04913801 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01327502 0,04906252 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01327502 0,04898728 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01327502 0,04891226 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01327502 0,04883747 ! hair follicle maturation GO:0048820 7 6 0,000 0,01327502 0,04876291 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01327502 0,04868857 ! Schwann cell development GO:0014044 15 6 0,000 0,01327502 0,04861446 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01327502 0,04854058 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01327502 0,04846692 ! subpallium development GO:0021544 10 6 0,000 0,01327502 0,04839349 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01327502 0,04832028 ! histone ubiquitination GO:0016574 8 6 0,000 0,01327502 0,04824729 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01327502 0,04817452 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01327502 0,04810196 ! G2 phase GO:0051319 16 6 0,000 0,01327502 0,04802963 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01327502 0,04795751 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01327502 0,04788561 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01327502 0,04781393 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01327502 0,04774246 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01327502 0,0476712 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01327502 0,04760015 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01327502 0,04752932 ! receptor internalization GO:0031623 10 6 0,000 0,01327502 0,0474587 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01327502 0,04738828 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01327502 0,04731808 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01327502 0,04724808 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01327502 0,04717829 ! protein deubiquitination GO:0016579 14 6 0,000 0,01327502 0,04710871 ! protein destabilization GO:0031648 9 6 0,000 0,01327502 0,04703933 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01327502 0,04697015 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01327502 0,04690118 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01327502 0,04683241 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01327502 0,04676384 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01327502 0,04669547 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01327502 0,0466273 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01327502 0,04655933 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01327502 0,04649156 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01327502 0,04642399 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01327502 0,04635661 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01327502 0,04628943 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01327502 0,04622244 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01327502 0,04615564 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01327502 0,04608904 ! catecholamine transport GO:0051937 9 6 0,000 0,01327502 0,04602263 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01327502 0,04595641 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01327502 0,04589038 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01327502 0,04582454 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01327502 0,04575889 ! maternal placenta development GO:0001893 12 6 0,000 0,01327502 0,04569342 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01327502 0,04562815 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01327502 0,04556306 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01327502 0,04549815 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01327502 0,04543343 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01327502 0,0453689 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01327502 0,04530454 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01327502 0,04524037 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,01345351 0,0457838 ! protein import into nucleus GO:0006606 158 80 1,000 0,01377886 0,04682476 ! T cell activation GO:0042110 168 81 1,000 0,01410761 0,04787435 ! nuclear import GO:0051170 161 81 1,000 0,01410761 0,04780692 ! response to drug GO:0042493 143 82 1,000 0,01443975 0,04886364 ! response to nutrient GO:0007584 125 82 1,000 0,01443975 0,04879501 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01443975 0,04872658 ! negative regulation of transport GO:0051051 153 84 1,000 0,01511414 0,05093085 ! negative regulation of growth GO:0045926 155 84 1,000 0,01511414 0,05085962 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,01545635 0,05193853 GO:0002696|positive regulation of leukocyte activation, ! tRNA transcription GO:0009304 14 7 0,000 0,01547058 0,05191384 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01547058 0,05184154 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01547058 0,05176944 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01547058 0,05169754 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01547058 0,05162583 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01547058 0,05155433 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01547058 0,05148302 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01547058 0,05141191 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01547058 0,051341 ! prostate gland development GO:0030850 13 7 0,000 0,01547058 0,05127028 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01547058 0,05119976 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01547058 0,05112943 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01547058 0,0510593 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01547058 0,05098935 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01547058 0,0509196 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01547058 0,05085004 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01547058 0,05078066 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01547058 0,05071148 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01547058 0,05064248 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01547058 0,05057368 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01547058 0,05050506 ! glycolipid transport GO:0046836 10 7 0,000 0,01547058 0,05043662 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01547058 0,05036837 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01547058 0,05030031 ! neuron adhesion GO:0007158 12 7 0,000 0,01547058 0,05023242 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01547058 0,05016473 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01547058 0,05009721 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01547058 0,05002987 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01547058 0,04996272 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01547058 0,04989575 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01547058 0,04982895 ! pericardium development GO:0060039 14 7 0,000 0,01547058 0,04976233 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01547058 0,0496959 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01547058 0,04962963 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01547058 0,04956355 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01547058 0,04949764 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01547058 0,04943191 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01547058 0,04936635 ! lipoprotein transport GO:0042953 14 7 0,000 0,01547058 0,04930096 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01547058 0,04923575 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01547058 0,04917071 ! rhythmic behavior GO:0007622 15 7 0,000 0,01547058 0,04910584 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01547058 0,04904114 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01547058 0,04897661 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01547058 0,04891226 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01547058 0,04884807 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01547058 0,04878404 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01547058 0,04872019 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01547058 0,0486565 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01547058 0,04859298 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01547058 0,04852963 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01547058 0,04846644 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01547058 0,04840342 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01547058 0,04834055 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01547058 0,04827785 ! spinal cord patterning GO:0021511 13 7 0,000 0,01547058 0,04821532 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01547058 0,04815294 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01547058 0,04809073 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01547058 0,04802868 ! adrenal gland development GO:0030325 17 7 0,000 0,01547058 0,04796679 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01547058 0,04790505 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01547058 0,04784348 ! ovulation GO:0030728 9 7 0,000 0,01547058 0,04778206 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01547058 0,0477208 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01547058 0,0476597 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01547058 0,04759875 ! microtubule nucleation GO:0007020 20 7 0,000 0,01547058 0,04753796 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01547058 0,04747733 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01547058 0,04741685 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01547058 0,04735652 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01547058 0,04729635 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01547058 0,04723633 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01547058 0,04717646 ! galactose metabolic process GO:0006012 13 7 0,000 0,01547058 0,04711674 ! vesicle fusion GO:0006906 17 7 0,000 0,01547058 0,04705718 ! response to dietary excess GO:0002021 8 7 0,000 0,01547058 0,04699776 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01547058 0,04693849 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01547058 0,04687938 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01547058 0,04682041 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01547058 0,04676159 ! organ growth GO:0035265 15 7 0,000 0,01547058 0,04670292 ! purine salvage GO:0043101 10 7 0,000 0,01547058 0,04664439 ! nucleoside transport GO:0015858 8 7 0,000 0,01547058 0,04658602 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01547058 0,04652778 ! parturition GO:0007567 14 7 0,000 0,01547058 0,0464697 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01547058 0,04641175 ! rRNA modification GO:0000154 14 7 0,000 0,01547058 0,04635396 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01547058 0,0462963 ! spindle checkpoint GO:0031577 15 7 0,000 0,01547058 0,04623879 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01547058 0,04618142 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01547058 0,0461242 ! macrophage differentiation GO:0030225 11 7 0,000 0,01547058 0,04606711 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01547058 0,04601017 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01547058 0,04595337 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01547058 0,0458967 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01547058 0,04584018 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01547058 0,0457838 ! fibrinolysis GO:0042730 10 7 0,000 0,01547058 0,04572755 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01547058 0,04567144 ! eating behavior GO:0042755 7 7 0,000 0,01547058 0,04561547 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01547058 0,04555964 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01547058 0,04550394 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01547058 0,04544838 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01547058 0,04539296 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01547058 0,04533767 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01547058 0,04528251 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01547058 0,04522749 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01547058 0,0451726 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01547058 0,04511785 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01547058 0,04506323 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01547058 0,04500874 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01547058 0,04495438 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01547058 0,04490015 ! regulation of meiosis GO:0040020 12 7 0,000 0,01547058 0,04484606 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01547058 0,04479209 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01547058 0,04473825 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01547058 0,04468455 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01547058 0,04463097 ! transcription termination GO:0006353 13 7 0,000 0,01547058 0,04457752 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01547058 0,04452419 ! anaphase GO:0051322 17 7 0,000 0,01547058 0,044471 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01547058 0,04441793 ! axonal fasciculation GO:0007413 18 7 0,000 0,01547058 0,04436499 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01547058 0,04431217 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01547058 0,04425948 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01547058 0,04420692 ! diuresis GO:0030146 12 7 0,000 0,01547058 0,04415448 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01547058 0,04410216 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01547058 0,04404997 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01547058 0,0439979 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01547058 0,04394596 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01547058 0,04389413 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01547058 0,04384243 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01547058 0,04379085 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01547058 0,0437394 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01547058 0,04368806 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01547058 0,04363684 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01547058 0,04358574 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01547058 0,04353477 ! lymph node development GO:0048535 10 7 0,000 0,01547058 0,04348391 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01547058 0,04343317 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01547058 0,04338255 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01547058 0,04333204 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01547058 0,04328166 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01547058 0,04323139 ! adult feeding behavior GO:0008343 9 7 0,000 0,01547058 0,04318124 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01547058 0,0431312 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01547058 0,04308128 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01547058 0,04303148 ! muscle adaptation GO:0043500 14 7 0,000 0,01547058 0,04298179 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01547058 0,04293221 ! retina homeostasis GO:0001895 12 7 0,000 0,01547058 0,04288275 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01547058 0,0428334 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01547058 0,04278417 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01547058 0,04273505 ! protein prenylation GO:0018342 18 7 0,000 0,01547058 0,04268604 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01547058 0,04263714 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01547058 0,04258836 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01547058 0,04253969 ! tube morphogenesis GO:0035239 176 86 1,000 0,01580189 0,04340109 ! mitochondrion organization GO:0007005 148 86 1,000 0,01580189 0,0433516 ! protein localization in nucleus GO:0034504 176 87 1,000 0,01615074 0,04425817 ! regulation of DNA binding GO:0051101 155 88 1,000 0,01650288 0,04517169 ! gland development GO:0048732 206 88 1,000 0,01650288 0,04512036 ! ossification GO:0001503 188 90 1,000 0,01721697 0,04701932 ! sex differentiation GO:0007548 145 90 1,000 0,01721697 0,04696601 ! bone development GO:0060348 189 91 1,000 0,01757889 0,04789898 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01766133 0,0480692 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01766133 0,04801488 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01766133 0,04796069 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01766133 0,04790662 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01766133 0,04785267 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01766133 0,04779884 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01766133 0,04774513 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01766133 0,04769155 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01766133 0,04763808 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01766133 0,04758474 ! meiotic prophase I GO:0007128 13 8 0,000 0,01766133 0,04753151 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01766133 0,0474784 ! oligopeptide transport GO:0006857 15 8 0,000 0,01766133 0,04742541 ! UTP metabolic process GO:0046051 8 8 0,000 0,01766133 0,04737254 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01766133 0,04731979 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01766133 0,04726715 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01766133 0,04721463 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01766133 0,04716223 ! succinate metabolic process GO:0006105 14 8 0,000 0,01766133 0,04710994 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01766133 0,04705777 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01766133 0,04700572 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01766133 0,04695378 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01766133 0,04690195 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01766133 0,04685024 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01766133 0,04679865 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01766133 0,04674716 ! reflex GO:0060004 16 8 0,000 0,01766133 0,04669579 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01766133 0,04664453 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01766133 0,04659339 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01766133 0,04654235 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01766133 0,04649143 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01766133 0,04644062 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01766133 0,04638992 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01766133 0,04633933 ! pigment granule organization GO:0048753 16 8 0,000 0,01766133 0,04628886 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01766133 0,04623849 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01766133 0,04618823 ! histidine metabolic process GO:0006547 16 8 0,000 0,01766133 0,04613808 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01766133 0,04608804 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01766133 0,0460381 ! glycine catabolic process GO:0006546 13 8 0,000 0,01766133 0,04598828 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01766133 0,04593856 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01766133 0,04588895 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01766133 0,04583945 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01766133 0,04579005 ! melanin metabolic process GO:0006582 15 8 0,000 0,01766133 0,04574076 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01766133 0,04569158 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01766133 0,0456425 ! macrophage activation GO:0042116 12 8 0,000 0,01766133 0,04559353 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01766133 0,04554466 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01766133 0,0454959 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01766133 0,04544724 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01766133 0,04539869 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01766133 0,04535023 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01766133 0,04530189 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01766133 0,04525364 ! osteoblast development GO:0002076 16 8 0,000 0,01766133 0,0452055 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01766133 0,04515746 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01766133 0,04510952 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01766133 0,04506169 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01766133 0,04501395 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01766133 0,04496632 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01766133 0,04491878 ! response to UV-B GO:0010224 16 8 0,000 0,01766133 0,04487135 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01766133 0,04482402 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01766133 0,04477679 ! intermediate filament organization GO:0045109 12 8 0,000 0,01766133 0,04472965 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01766133 0,04468262 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01766133 0,04463568 ! cellular extravasation GO:0045123 12 8 0,000 0,01766133 0,04458885 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01766133 0,04454211 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01766133 0,04449547 ! response to antibiotic GO:0046677 11 8 0,000 0,01766133 0,04444892 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01766133 0,04440248 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01766133 0,04435613 ! DNA topological change GO:0006265 12 8 0,000 0,01766133 0,04430987 ! response to tropane GO:0014073 15 8 0,000 0,01766133 0,04426372 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01766133 0,04421766 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01766133 0,04417169 ! melanosome transport GO:0032402 13 8 0,000 0,01766133 0,04412583 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,01766133 0,04408005 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01766133 0,04403437 ! mast cell activation GO:0045576 14 8 0,000 0,01766133 0,04398879 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01766133 0,0439433 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01766133 0,0438979 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01766133 0,0438526 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01766133 0,04380739 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01766133 0,04376228 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01766133 0,04371725 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01766133 0,04367232 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01766133 0,04362748 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01766133 0,04358274 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01766133 0,04353808 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01766133 0,04349352 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01766133 0,04344905 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01766133 0,04340467 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01766133 0,04336038 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01766133 0,04331618 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01766133 0,04327207 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01766133 0,04322805 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01766133 0,04318412 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01766133 0,04314027 ! hormone catabolic process GO:0042447 17 8 0,000 0,01766133 0,04309652 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01766133 0,04305286 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01766133 0,04300928 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01766133 0,04296579 ! ATP catabolic process GO:0006200 11 8 0,000 0,01766133 0,04292239 ! blastocyst growth GO:0001832 19 8 0,000 0,01766133 0,04287908 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01766133 0,04283586 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01766133 0,04279272 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01766133 0,04274967 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01766133 0,0427067 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01766133 0,04266383 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01766133 0,04262103 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01766133 0,04257833 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01766133 0,04253571 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01766133 0,04249317 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01766133 0,04245072 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01766133 0,04240835 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01766133 0,04236607 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01766133 0,04232387 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01766133 0,04228176 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01766133 0,04223973 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01766133 0,04219779 ! regulation of T cell activation GO:0050863 158 94 1,000 0,01868396 0,04459683 ! forebrain development GO:0030900 188 95 1,000 0,0190587 0,04544622 ! leukocyte differentiation GO:0002521 202 96 1,000 0,01943661 0,04630147 ! axon extension GO:0048675 15 9 0,000 0,01984728 0,047233 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01984728 0,04718632 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01984728 0,04713974 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01984728 0,04709325 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01984728 0,04704686 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01984728 0,04700055 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01984728 0,04695434 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01984728 0,04690821 ! phosphate transport GO:0006817 19 9 0,000 0,01984728 0,04686218 ! reproductive behavior GO:0019098 19 9 0,000 0,01984728 0,04681623 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01984728 0,04677038 ! CTP metabolic process GO:0046036 9 9 0,000 0,01984728 0,04672462 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01984728 0,04667894 ! GTP metabolic process GO:0046039 9 9 0,000 0,01984728 0,04663336 ! RNA methylation GO:0001510 15 9 0,000 0,01984728 0,04658786 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01984728 0,04654246 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01984728 0,04649714 ! artery development GO:0060840 24 9 0,000 0,01984728 0,04645191 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01984728 0,04640676 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01984728 0,04636171 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01984728 0,04631674 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01984728 0,04627186 ! chemosensory behavior GO:0007635 20 9 0,000 0,01984728 0,04622707 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01984728 0,04618236 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01984728 0,04613774 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01984728 0,0460932 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01984728 0,04604876 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01984728 0,04600439 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01984728 0,04596011 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01984728 0,04591592 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01984728 0,04587181 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01984728 0,04582779 ! protein targeting to ER GO:0045047 22 9 0,000 0,01984728 0,04578385 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01984728 0,04574 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01984728 0,04569623 ! T cell selection GO:0045058 23 9 0,000 0,01984728 0,04565254 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01984728 0,04560894 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01984728 0,04556542 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01984728 0,04552198 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01984728 0,04547863 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01984728 0,04543536 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01984728 0,04539217 ! mannose metabolic process GO:0006013 13 9 0,000 0,01984728 0,04534906 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01984728 0,04530603 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01984728 0,04526309 ! receptor clustering GO:0043113 18 9 0,000 0,01984728 0,04522023 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01984728 0,04517744 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01984728 0,04513474 ! ruffle organization GO:0031529 15 9 0,000 0,01984728 0,04509212 ! retinol metabolic process GO:0042572 18 9 0,000 0,01984728 0,04504958 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01984728 0,04500712 ! behavioral fear response GO:0001662 22 9 0,000 0,01984728 0,04496475 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01984728 0,04492245 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01984728 0,04488022 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01984728 0,04483808 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,01984728 0,04479602 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01984728 0,04475404 ! segment specification GO:0007379 13 9 0,000 0,01984728 0,04471213 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01984728 0,04467031 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01984728 0,04462856 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01984728 0,04458689 ! response to amine stimulus GO:0014075 13 9 0,000 0,01984728 0,0445453 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01984728 0,04450378 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01984728 0,04446235 ! erythrocyte development GO:0048821 15 9 0,000 0,01984728 0,04442099 ! gas homeostasis GO:0033483 16 9 0,000 0,01984728 0,0443797 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01984728 0,0443385 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01984728 0,04429736 ! renal water homeostasis GO:0003091 14 9 0,000 0,01984728 0,04425631 ! postreplication repair GO:0006301 22 9 0,000 0,01984728 0,04421533 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01984728 0,04417443 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01984728 0,0441336 ! icosanoid secretion GO:0032309 15 9 0,000 0,01984728 0,04409285 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01984728 0,04405218 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01984728 0,04401158 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01984728 0,04397105 ! regulation of cell division GO:0051302 15 9 0,000 0,01984728 0,0439306 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01984728 0,04389022 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01984728 0,04384992 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01984728 0,04380969 ! sterol catabolic process GO:0016127 11 9 0,000 0,01984728 0,04376953 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01984728 0,04372945 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01984728 0,04368944 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01984728 0,04364951 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01984728 0,04360964 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01984728 0,04356985 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01984728 0,04353014 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01984728 0,04349049 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01984728 0,04345092 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01984728 0,04341142 ! purine base metabolic process GO:0006144 21 9 0,000 0,01984728 0,04337199 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01984728 0,04333263 ! pigment granule transport GO:0051904 17 9 0,000 0,01984728 0,04329334 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01984728 0,04325413 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01984728 0,04321499 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01984728 0,04317591 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01984728 0,04313691 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01984728 0,04309798 ! mitochondrion localization GO:0051646 15 9 0,000 0,01984728 0,04305912 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,02058919 0,04462845 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 1,000 0,02097961 0,04543379 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02202844 0,04766225 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02202844 0,04761942 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02202844 0,04757668 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02202844 0,04753401 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02202844 0,04749142 ! synapsis GO:0007129 13 10 0,000 0,02202844 0,0474489 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02202844 0,04740646 ! N-glycan processing GO:0006491 20 10 0,000 0,02202844 0,04736409 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02202844 0,0473218 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02202844 0,04727959 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02202844 0,04723745 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02202844 0,04719539 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02202844 0,0471534 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02202844 0,04711148 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02202844 0,04706964 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02202844 0,04702788 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02202844 0,04698619 ! androgen metabolic process GO:0008209 17 10 0,000 0,02202844 0,04694457 ! phospholipid efflux GO:0033700 16 10 0,000 0,02202844 0,04690303 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02202844 0,04686156 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02202844 0,04682016 ! pathogenesis GO:0009405 13 10 0,000 0,02202844 0,04677883 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02202844 0,04673758 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02202844 0,0466964 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02202844 0,0466553 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02202844 0,04661427 ! endoderm development GO:0007492 16 10 0,000 0,02202844 0,0465733 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02202844 0,04653241 ! arginine catabolic process GO:0006527 13 10 0,000 0,02202844 0,0464916 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02202844 0,04645085 ! proline metabolic process GO:0006560 13 10 0,000 0,02202844 0,04641017 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02202844 0,04636957 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02202844 0,04632904 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02202844 0,04628858 ! V(D)J recombination GO:0033151 28 10 0,000 0,02202844 0,04624818 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02202844 0,04620786 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02202844 0,04616761 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02202844 0,04612743 ! B cell proliferation GO:0042100 18 10 0,000 0,02202844 0,04608732 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02202844 0,04604728 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02202844 0,04600731 ! multicellular organism growth GO:0035264 18 10 0,000 0,02202844 0,04596741 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02202844 0,04592757 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02202844 0,04588781 ! epithelial cell development GO:0002064 20 10 0,000 0,02202844 0,04584811 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02202844 0,04580849 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02202844 0,04576893 ! macroautophagy GO:0016236 17 10 0,000 0,02202844 0,04572944 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02202844 0,04569002 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02202844 0,04565066 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02202844 0,04561138 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02202844 0,04557216 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02202844 0,04553301 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02202844 0,04549392 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02202844 0,04545491 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02202844 0,04541596 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02202844 0,04537707 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02202844 0,04533825 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02202844 0,0452995 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02202844 0,04526082 ! response to dsRNA GO:0043331 20 10 0,000 0,02202844 0,0452222 ! DNA ligation GO:0006266 19 10 0,000 0,02202844 0,04518365 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02202844 0,04514516 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02202844 0,04510674 ! melanosome localization GO:0032400 16 10 0,000 0,02202844 0,04506838 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02202844 0,04503009 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02202844 0,04499187 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02202844 0,04495371 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02202844 0,04491561 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02202844 0,04487758 ! mRNA cleavage GO:0006379 17 10 0,000 0,02202844 0,04483961 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02202844 0,04480171 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02202844 0,04476387 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02202844 0,04472609 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02202844 0,04468838 ! salivary gland development GO:0007431 27 10 0,000 0,02202844 0,04465073 ! prophase GO:0051324 15 10 0,000 0,02202844 0,04461315 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02202844 0,04457563 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02202844 0,04453817 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02202844 0,04450077 ! midbrain development GO:0030901 13 10 0,000 0,02202844 0,04446344 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02202844 0,04442617 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02202844 0,04438896 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02202844 0,04435182 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02202844 0,04431473 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02202844 0,04427771 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02202844 0,04424075 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02202844 0,04420385 ! detection of calcium ion GO:0005513 23 10 0,000 0,02202844 0,04416702 ! oocyte development GO:0048599 17 10 0,000 0,02202844 0,04413024 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02202844 0,04409353 ! blastocyst formation GO:0001825 17 10 0,000 0,02202844 0,04405687 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02202844 0,04402028 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02202844 0,04398375 ! activation of innate immune response GO:0002218 12 10 0,000 0,02202844 0,04394728 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02202844 0,04391087 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02202844 0,04387452 ! response to nicotine GO:0035094 20 10 0,000 0,02202844 0,04383823 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02202844 0,043802 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02202844 0,04376583 ! respiratory burst GO:0045730 17 11 0,000 0,02420481 0,04805014 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02420481 0,04801053 ! neuron fate specification GO:0048665 17 11 0,000 0,02420481 0,04797098 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02420481 0,0479315 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02420481 0,04789209 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02420481 0,04785273 ! thyroid gland development GO:0030878 26 11 0,000 0,02420481 0,04781344 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02420481 0,04777422 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02420481 0,04773506 ! response to pain GO:0048265 24 11 0,000 0,02420481 0,04769597 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02420481 0,04765694 ! T cell proliferation GO:0042098 26 11 0,000 0,02420481 0,04761797 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02420481 0,04757907 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,02420481 0,04754022 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02420481 0,04750145 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02420481 0,04746273 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02420481 0,04742408 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02420481 0,0473855 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02420481 0,04734697 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02420481 0,04730851 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02420481 0,04727011 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02420481 0,04723177 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02420481 0,0471935 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,02420481 0,04715528 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02420481 0,04711713 ! UV protection GO:0009650 19 11 0,000 0,02420481 0,04707904 ! adult heart development GO:0007512 14 11 0,000 0,02420481 0,04704101 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02420481 0,04700305 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02420481 0,04696514 ! temperature homeostasis GO:0001659 17 11 0,000 0,02420481 0,0469273 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02420481 0,04688951 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02420481 0,04685179 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02420481 0,04681413 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02420481 0,04677653 ! regulation of organ growth GO:0046620 13 11 0,000 0,02420481 0,04673899 ! pigment granule localization GO:0051875 20 11 0,000 0,02420481 0,0467015 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02420481 0,04666408 ! vasoconstriction GO:0042310 18 11 0,000 0,02420481 0,04662672 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02420481 0,04658942 ! embryonic axis specification GO:0000578 18 11 0,000 0,02420481 0,04655218 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02420481 0,046515 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02420481 0,04647787 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02420481 0,04644081 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02420481 0,04640381 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02420481 0,04636686 GO:0006305|DNA alkylation, ! zymogen activation GO:0031638 15 11 0,000 0,02420481 0,04632997 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02420481 0,04629314 ! nucleosome positioning GO:0016584 15 11 0,000 0,02420481 0,04625637 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02420481 0,04621966 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02420481 0,04618301 ! acid secretion GO:0046717 18 11 0,000 0,02420481 0,04614641 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02420481 0,04610988 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02420481 0,0460734 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02420481 0,04603698 ! oocyte differentiation GO:0009994 18 11 0,000 0,02420481 0,04600061 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02420481 0,04596431 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02420481 0,04592806 ! cholesterol efflux GO:0033344 19 11 0,000 0,02420481 0,04589186 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02420481 0,04585573 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02420481 0,04581965 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02420481 0,04578363 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02420481 0,04574766 ! embryonic gut development GO:0048566 15 11 0,000 0,02420481 0,04571175 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02420481 0,0456759 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02420481 0,04564011 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02420481 0,04560437 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02420481 0,04556868 ! defense response to fungus GO:0050832 13 11 0,000 0,02420481 0,04553305 ! developmental induction GO:0031128 19 11 0,000 0,02420481 0,04549748 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02420481 0,04546196 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02420481 0,0454265 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02420481 0,0453911 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02420481 0,04535574 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02420481 0,04532045 ! nucleus localization GO:0051647 19 11 0,000 0,02420481 0,04528521 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02420481 0,04525002 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02637641 0,04927147 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02637641 0,04923324 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02637641 0,04919508 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02637641 0,04915697 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02637641 0,04911893 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02637641 0,04908094 ! cartilage condensation GO:0001502 20 12 0,000 0,02637641 0,04904301 ! mating GO:0007618 17 12 0,000 0,02637641 0,04900514 ! protein complex disassembly GO:0043241 27 12 0,000 0,02637641 0,04896732 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02637641 0,04892957 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02637641 0,04889187 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,02637641 0,04885424 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02637641 0,04881666 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02637641 0,04877913 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02637641 0,04874167 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02637641 0,04870426 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02637641 0,04866691 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02637641 0,04862962 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02637641 0,04859238 ! drug transport GO:0015893 16 12 0,000 0,02637641 0,0485552 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02637641 0,04851808 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02637641 0,04848102 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02637641 0,04844401 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02637641 0,04840706 ! focal adhesion formation GO:0048041 35 12 0,000 0,02637641 0,04837016 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02637641 0,04833332 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02637641 0,04829654 ! forebrain cell migration GO:0021885 21 12 0,000 0,02637641 0,04825981 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02637641 0,04822314 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02637641 0,04818652 ! entry into host cell GO:0030260 32 12 0,000 0,02637641 0,04814996 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02637641 0,04811346 ! monoamine transport GO:0015844 18 12 0,000 0,02637641 0,04807701 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02637641 0,04804061 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02637641 0,04800428 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02637641 0,04796799 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02637641 0,04793176 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02637641 0,04789559 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02637641 0,04785947 ! protein homotetramerization GO:0051289 21 12 0,000 0,02637641 0,0478234 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02637641 0,04778739 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02637641 0,04775143 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02637641 0,04771553 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02637641 0,04767968 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02637641 0,04764388 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02637641 0,04760814 ! cranial nerve development GO:0021545 20 12 0,000 0,02637641 0,04757245 ! fucose catabolic process GO:0019317 22 12 0,000 0,02637641 0,04753682 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02637641 0,04750124 ! histone methylation GO:0016571 26 12 0,000 0,02637641 0,04746571 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02637641 0,04743023 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02637641 0,04739481 ! gland morphogenesis GO:0022612 29 12 0,000 0,02637641 0,04735944 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02637641 0,04732413 ! T cell homeostasis GO:0043029 25 12 0,000 0,02637641 0,04728886 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02637641 0,04725365 ! spleen development GO:0048536 22 12 0,000 0,02637641 0,04721849 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02637641 0,04718338 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02637641 0,04714833 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02637641 0,04711333 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02637641 0,04707838 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02637641 0,04704348 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02637641 0,04700863 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02637641 0,04697384 ! response to cold GO:0009409 17 12 0,000 0,02637641 0,04693909 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02637641 0,0469044 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02637641 0,04686976 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02854326 0,05068271 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02854326 0,05064533 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02854326 0,05060801 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02854326 0,05057075 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02854326 0,05053354 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02854326 0,05049638 ! lipid localization GO:0010876 28 13 0,000 0,02854326 0,05045928 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02854326 0,05042223 ! organelle fusion GO:0048284 32 13 0,000 0,02854326 0,05038523 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02854326 0,05034829 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02854326 0,05031141 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02854326 0,05027458 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02854326 0,0502378 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02854326 0,05020108 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02854326 0,05016441 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02854326 0,05012779 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02854326 0,05009123 ! methionine metabolic process GO:0006555 27 13 0,000 0,02854326 0,05005472 ! plasma membrane organization GO:0007009 24 13 0,000 0,02854326 0,05001826 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02854326 0,04998186 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02854326 0,04994551 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02854326 0,04990921 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02854326 0,04987297 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02854326 0,04983677 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02854326 0,04980063 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02854326 0,04976455 ! exocrine system development GO:0035272 32 13 0,000 0,02854326 0,04972851 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02854326 0,04969253 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02854326 0,0496566 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02854326 0,04962072 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02854326 0,04958489 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02854326 0,04954912 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02854326 0,04951339 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02854326 0,04947772 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02854326 0,0494421 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02854326 0,04940653 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02854326 0,04937101 ! ribosome assembly GO:0042255 17 13 0,000 0,02854326 0,04933554 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02854326 0,04930013 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02854326 0,04926476 ! chromatin silencing GO:0006342 26 13 0,000 0,02854326 0,04922944 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02854326 0,04919418 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02854326 0,04915897 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02854326 0,0491238 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02854326 0,04908869 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02854326 0,04905362 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02854326 0,04901861 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02854326 0,04898365 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02854326 0,04894873 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02854326 0,04891387 ! embryonic placenta development GO:0001892 23 13 0,000 0,02854326 0,04887906 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02854326 0,04884429 ! insulin secretion GO:0030073 23 13 0,000 0,02854326 0,04880958 ! actin filament polymerization GO:0030041 24 13 0,000 0,02854326 0,04877491 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02854326 0,04874029 ! acrosome reaction GO:0007340 18 13 0,000 0,02854326 0,04870573 ! rRNA transcription GO:0009303 25 14 0,000 0,03070535 0,05235795 ! lactation GO:0007595 26 14 0,000 0,03070535 0,05232087 ! reproductive cellular process GO:0048610 20 14 0,000 0,03070535 0,05228384 ! tRNA modification GO:0006400 20 14 0,000 0,03070535 0,05224686 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03070535 0,05220994 ! regulation of S phase GO:0033261 23 14 0,000 0,03070535 0,05217307 ! water transport GO:0006833 21 14 0,000 0,03070535 0,05213625 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03070535 0,05209948 ! non-recombinational repair GO:0000726 25 14 0,000 0,03070535 0,05206277 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03070535 0,0520261 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03070535 0,05198949 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03070535 0,05195293 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03070535 0,05191642 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03070535 0,05187996 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03070535 0,05184356 ! palate development GO:0060021 31 14 0,000 0,03070535 0,0518072 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03070535 0,05177089 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03070535 0,05173464 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03070535 0,05169844 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03070535 0,05166228 ! arginine metabolic process GO:0006525 17 14 0,000 0,03070535 0,05162618 ! regulation of heart rate GO:0002027 24 14 0,000 0,03070535 0,05159013 ! organic alcohol transport GO:0015850 29 14 0,000 0,03070535 0,05155413 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03070535 0,05151818 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03070535 0,05148228 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03070535 0,05144643 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03070535 0,05141062 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03070535 0,05137487 ! L-amino acid transport GO:0015807 30 14 0,000 0,03070535 0,05133917 ! bone mineralization GO:0030282 17 14 0,000 0,03070535 0,05130352 ! stem cell development GO:0048864 43 14 0,000 0,03070535 0,05126792 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03070535 0,05123236 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03070535 0,05119686 ! cerebellum development GO:0021549 21 14 0,000 0,03070535 0,0511614 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03070535 0,051126 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03070535 0,05109064 ! cofactor transport GO:0051181 26 14 0,000 0,03070535 0,05105533 ! NADP metabolic process GO:0006739 24 14 0,000 0,03070535 0,05102007 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03070535 0,05098486 ! intestinal absorption GO:0050892 25 14 0,000 0,03070535 0,0509497 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03070535 0,05091459 ! oxygen transport GO:0015671 21 14 0,000 0,03070535 0,05087952 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03070535 0,05084451 ! male genitalia development GO:0030539 24 14 0,000 0,03070535 0,05080954 ! regulation of axon extension GO:0030516 37 14 0,000 0,03070535 0,05077462 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03070535 0,05073974 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0328627 0,05426744 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0328627 0,05423021 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0328627 0,05419305 ! superoxide anion generation GO:0042554 20 15 0,000 0,0328627 0,05415593 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0328627 0,05411886 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0328627 0,05408184 ! copper ion transport GO:0006825 20 15 0,000 0,0328627 0,05404488 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0328627 0,05400796 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0328627 0,05397109 ! sulfate transport GO:0008272 23 15 0,000 0,0328627 0,05393428 ! response to cAMP GO:0051591 22 15 0,000 0,0328627 0,05389751 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0328627 0,0538608 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0328627 0,05382413 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0328627 0,05378752 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0328627 0,05375095 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0328627 0,05371444 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0328627 0,05367797 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0328627 0,05364156 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0328627 0,05360519 ! pituitary gland development GO:0021983 29 15 0,000 0,0328627 0,05356887 ! vesicle coating GO:0006901 33 15 0,000 0,0328627 0,0535326 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0328627 0,05349638 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0328627 0,05346021 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0328627 0,05342409 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0328627 0,05338802 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0328627 0,05335199 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0328627 0,05331602 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0328627 0,05328009 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0328627 0,05324421 ! histone deacetylation GO:0016575 20 15 0,000 0,0328627 0,05320838 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0328627 0,0531726 ! tissue regeneration GO:0042246 26 15 0,000 0,0328627 0,05313686 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0328627 0,05310118 ! water homeostasis GO:0030104 27 15 0,000 0,0328627 0,05306554 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0328627 0,05302995 ! muscle maintenance GO:0046716 26 15 0,000 0,0328627 0,05299441 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0328627 0,05295891 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0328627 0,05292346 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0328627 0,05288806 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0328627 0,05285271 ! cell killing GO:0001906 29 15 0,000 0,0328627 0,0528174 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0328627 0,05278214 ! detection of bacterium GO:0016045 18 15 0,000 0,0328627 0,05274693 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0328627 0,05271177 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0328627 0,05267665 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0328627 0,05264158 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0328627 0,05260656 ! peptide hormone processing GO:0016486 23 15 0,000 0,0328627 0,05257158 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03501532 0,05597798 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03501532 0,05594081 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03501532 0,05590369 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03501532 0,05586662 ! bone remodeling GO:0046849 27 16 0,000 0,03501532 0,0558296 ! filopodium assembly GO:0046847 32 16 0,000 0,03501532 0,05579262 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03501532 0,0557557 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03501532 0,05571882 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03501532 0,055682 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03501532 0,05564522 ! startle response GO:0001964 28 16 0,000 0,03501532 0,05560849 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03501532 0,05557181 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03501532 0,05553517 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03501532 0,05549859 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03501532 0,05546205 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03501532 0,05542557 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03501532 0,05538913 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03501532 0,05535273 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03501532 0,05531639 ! response to osmotic stress GO:0006970 25 16 0,000 0,03501532 0,05528009 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03501532 0,05524384 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03501532 0,05520764 ! fructose metabolic process GO:0006000 25 16 0,000 0,03501532 0,05517149 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03501532 0,05513538 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03501532 0,05509932 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03501532 0,05506331 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03501532 0,05502734 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03501532 0,05499142 ! axon cargo transport GO:0008088 43 16 0,000 0,03501532 0,05495555 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03501532 0,05491973 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03501532 0,05488395 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,03501532 0,05484822 ! DNA replication initiation GO:0006270 27 16 0,000 0,03501532 0,05481253 ! neuron recognition GO:0008038 35 16 0,000 0,03501532 0,05477689 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03501532 0,0547413 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03501532 0,05470575 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03501532 0,05467025 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03501532 0,0546348 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03501532 0,05459939 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03501532 0,05456403 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03501532 0,05452871 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03501532 0,05449344 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03501532 0,05445822 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,03501532 0,05442304 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03716322 0,05772415 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,03716322 0,05768691 ! metencephalon development GO:0022037 30 17 0,000 0,03716322 0,05764972 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03716322 0,05761257 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03716322 0,05757547 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03716322 0,05753842 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03716322 0,05750142 ! signal complex assembly GO:0007172 41 17 0,000 0,03716322 0,05746447 ! endothelial cell migration GO:0043542 28 17 0,000 0,03716322 0,05742756 ! inositol metabolic process GO:0006020 28 17 0,000 0,03716322 0,0573907 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03716322 0,05735389 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03716322 0,05731712 ! glial cell development GO:0021782 27 17 0,000 0,03716322 0,0572804 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03716322 0,05724373 ! adult walking behavior GO:0007628 33 17 0,000 0,03716322 0,05720711 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03716322 0,05717053 ! heart looping GO:0001947 30 17 0,000 0,03716322 0,057134 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03716322 0,05709752 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03716322 0,05706108 ! myoblast differentiation GO:0045445 45 17 0,000 0,03716322 0,05702469 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03716322 0,05698834 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03716322 0,05695204 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03716322 0,05691579 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03716322 0,05687959 ! glycine metabolic process GO:0006544 28 17 0,000 0,03716322 0,05684343 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03716322 0,05680731 ! NAD metabolic process GO:0019674 29 17 0,000 0,03716322 0,05677124 ! membrane budding GO:0006900 37 17 0,000 0,03716322 0,05673522 ! DNA integration GO:0015074 29 17 0,000 0,03716322 0,05669925 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03716322 0,05666331 ! regulation of protein binding GO:0043393 33 17 0,000 0,03716322 0,05662743 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03716322 0,05659159 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03716322 0,05655579 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03716322 0,05652004 ! genitalia development GO:0048806 30 17 0,000 0,03716322 0,05648434 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03716322 0,05644868 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03716322 0,05641307 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03716322 0,0563775 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03716322 0,05634197 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03716322 0,05630649 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03716322 0,05627106 ! steroid catabolic process GO:0006706 31 17 0,000 0,03716322 0,05623567 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03716322 0,05620032 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03716322 0,05616502 ! gas transport GO:0015669 25 17 0,000 0,03716322 0,05612976 ! organic cation transport GO:0015695 31 17 0,000 0,03716322 0,05609455 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03716322 0,05605938 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03716322 0,05602425 ! microspike assembly GO:0030035 36 17 0,000 0,03716322 0,05598917 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03716322 0,05595414 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03716322 0,05591914 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03930641 0,05910702 ! neuron maturation GO:0042551 42 18 0,000 0,03930641 0,0590701 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03930641 0,05903323 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03930641 0,0589964 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,03930641 0,05895962 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03930641 0,05892288 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03930641 0,05888619 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03930641 0,05884955 ! memory GO:0007613 31 18 0,000 0,03930641 0,05881295 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03930641 0,0587764 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03930641 0,05873989 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03930641 0,05870343 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03930641 0,05866702 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03930641 0,05863064 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03930641 0,05859432 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03930641 0,05855804 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03930641 0,0585218 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03930641 0,05848561 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03930641 0,05844946 ! response to fungus GO:0009620 21 18 0,000 0,03930641 0,05841336 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03930641 0,0583773 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03930641 0,05834129 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03930641 0,05830532 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03930641 0,0582694 ! vitamin transport GO:0051180 27 18 0,000 0,03930641 0,05823352 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03930641 0,05819768 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03930641 0,05816189 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03930641 0,05812614 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03930641 0,05809044 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03930641 0,05805477 ! nerve development GO:0021675 28 18 0,000 0,03930641 0,05801916 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03930641 0,05798359 ! protein secretion GO:0009306 39 19 0,000 0,0414449 0,06110076 ! positive regulation of translation GO:0045727 30 19 0,000 0,0414449 0,06106334 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0414449 0,06102597 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0414449 0,06098865 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0414449 0,06095137 ! skin development GO:0043588 36 19 0,000 0,0414449 0,06091414 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0414449 0,06087695 ! lipid phosphorylation GO:0046834 35 19 0,000 0,0414449 0,0608398 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0414449 0,06080271 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0414449 0,06076566 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0414449 0,06072865 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0414449 0,06069169 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0414449 0,06065477 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0414449 0,0606179 ! cerebral cortex development GO:0021987 36 19 0,000 0,0414449 0,06058107 ! pigmentation during development GO:0048066 41 19 0,000 0,0414449 0,06054429 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,0414449 0,06050755 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,0414449 0,06047086 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0414449 0,06043421 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0414449 0,0603976 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0414449 0,06036104 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0414449 0,06032453 ! peptide cross-linking GO:0018149 37 19 0,000 0,0414449 0,06028805 ! protein export from nucleus GO:0006611 36 19 0,000 0,0414449 0,06025163 ! heart process GO:0003015 30 19 0,000 0,0414449 0,06021524 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0414449 0,0601789 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0414449 0,06014261 ! visual learning GO:0008542 36 19 0,000 0,0414449 0,06010635 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0414449 0,06007014 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0414449 0,06003398 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0414449 0,05999786 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0414449 0,05996178 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0414449 0,05992575 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0414449 0,05988975 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0414449 0,05985381 ! cilium assembly GO:0042384 37 19 0,000 0,0414449 0,0598179 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0414449 0,05978204 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04357871 0,06282227 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04357871 0,06278465 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04357871 0,06274708 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04357871 0,06270955 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04357871 0,06267207 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,04357871 0,06263463 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04357871 0,06259724 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04357871 0,06255989 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04357871 0,06252258 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04357871 0,06248532 ! response to alkaloid GO:0043279 38 20 0,000 0,04357871 0,06244811 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04357871 0,06241093 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04357871 0,06237381 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04357871 0,06233672 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04357871 0,06229968 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04357871 0,06226269 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04357871 0,06222574 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04357871 0,06218883 ! body fluid secretion GO:0007589 31 20 0,000 0,04357871 0,06215197 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04357871 0,06211515 ! peptide secretion GO:0002790 35 20 0,000 0,04357871 0,06207837 ! stem cell differentiation GO:0048863 53 20 0,000 0,04357871 0,06204164 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04357871 0,06200495 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04357871 0,0619683 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04357871 0,0619317 ! sensory perception of pain GO:0019233 30 20 0,000 0,04357871 0,06189514 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04357871 0,06185862 ! diencephalon development GO:0021536 34 20 0,000 0,04357871 0,06182215 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04357871 0,06178572 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04357871 0,06174933 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04357871 0,06171299 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04357871 0,06167669 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04357871 0,06164043 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04357871 0,06160421 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04357871 0,06156804 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04357871 0,06153191 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04357871 0,06149582 ! regulation of glucose import GO:0046324 29 20 0,000 0,04357871 0,06145977 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04357871 0,06142377 ! actin filament-based movement GO:0030048 43 20 0,000 0,04357871 0,0613878 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04357871 0,06135188 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,04357871 0,06131601 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04357871 0,06128017 ! negative regulation of translation GO:0017148 29 20 0,000 0,04357871 0,06124437 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04357871 0,06120862 ! regulation of cell killing GO:0031341 42 21 0,000 0,04570783 0,06416163 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04570783 0,06412422 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04570783 0,06408685 ! hormone secretion GO:0046879 38 21 0,000 0,04570783 0,06404953 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04570783 0,06401225 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04570783 0,06397501 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04570783 0,06393781 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04570783 0,06390066 ! axis specification GO:0009798 38 21 0,000 0,04570783 0,06386355 ! ovarian follicle development GO:0001541 35 21 0,000 0,04570783 0,06382649 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,04570783 0,06378947 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04570783 0,06375249 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04570783 0,06371555 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04570783 0,06367866 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04570783 0,06364181 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04570783 0,063605 ! cytolysis GO:0019835 24 21 0,000 0,04570783 0,06356823 ! vasodilation GO:0042311 39 21 0,000 0,04570783 0,06353151 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04570783 0,06349483 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,04570783 0,06345819 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04570783 0,06342159 ! oogenesis GO:0048477 36 21 0,000 0,04570783 0,06338504 ! DNA modification GO:0006304 34 21 0,000 0,04570783 0,06334853 ! collagen fibril organization GO:0030199 59 21 0,000 0,04570783 0,06331206 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04570783 0,06327563 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04570783 0,06323924 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04570783 0,0632029 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04570783 0,06316659 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04570783 0,06313033 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04570783 0,06309411 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04570783 0,06305794 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04570783 0,0630218 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04570783 0,0629857 ! collagen catabolic process GO:0030574 28 21 0,000 0,04570783 0,06294965 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04570783 0,06291364 ! gut development GO:0048565 39 21 0,000 0,04570783 0,06287767 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04783228 0,06576256 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04783228 0,065725 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04783228 0,06568749 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04783228 0,06565002 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04783228 0,06561259 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04783228 0,0655752 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04783228 0,06553786 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04783228 0,06550056 ! regeneration GO:0031099 41 22 0,000 0,04783228 0,0654633 ! keratinization GO:0031424 28 22 0,000 0,04783228 0,06542608 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04783228 0,06538891 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04783228 0,06535178 ! sensory perception of taste GO:0050909 28 22 0,000 0,04783228 0,06531469 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04783228 0,06527764 ! vacuolar transport GO:0007034 36 22 0,000 0,04783228 0,06524063 ! lysosome organization GO:0007040 41 22 0,000 0,04783228 0,06520367 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04783228 0,06516675 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04783228 0,06512987 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,04783228 0,06509303 ! fucose metabolic process GO:0006004 39 22 0,000 0,04783228 0,06505623 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04783228 0,06501948 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04783228 0,06498277 ! ureteric bud development GO:0001657 43 22 0,000 0,04783228 0,06494609 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04783228 0,06490946 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04783228 0,06487287 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04783228 0,06483633 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,04783228 0,06479982 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04783228 0,06476335 ! sarcomere organization GO:0045214 30 22 0,000 0,04783228 0,06472693 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04783228 0,06469054 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04783228 0,0646542 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04783228 0,0646179 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04783228 0,06458164 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04783228 0,06454542 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,04783228 0,06450924 ! protein stabilization GO:0050821 39 22 0,000 0,04783228 0,0644731 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,04995208 0,06729267 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,04995208 0,06725501 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,04995208 0,0672174 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,04995208 0,06717982 ! gluconeogenesis GO:0006094 33 23 0,000 0,04995208 0,06714229 ! viral genome replication GO:0019079 41 23 0,000 0,04995208 0,0671048 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04995208 0,06706736 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04995208 0,06702995 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04995208 0,06699259 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04995208 0,06695527 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,04995208 0,06691799 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04995208 0,06688075 ! visual behavior GO:0007632 42 23 0,000 0,04995208 0,06684355 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,04995208 0,06680639 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,04995208 0,06676928 ! response to ethanol GO:0045471 46 23 0,000 0,04995208 0,06673221 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04995208 0,06669517 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,04995208 0,06665818 ! peroxisome organization GO:0007031 37 23 0,000 0,04995208 0,06662123 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04995208 0,06658432 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04995208 0,06654746 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04995208 0,06651063 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04995208 0,06647384 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04995208 0,06643709 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04995208 0,06640039 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04995208 0,06636372 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04995208 0,0663271 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04995208 0,06629052 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04995208 0,06625397 ! fatty acid transport GO:0015908 44 23 0,000 0,04995208 0,06621747 ! platelet activation GO:0030168 37 23 0,000 0,04995208 0,066181 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,04995208 0,06614458 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04995208 0,0661082 ! hormone transport GO:0009914 40 23 0,000 0,04995208 0,06607186 ! cell-cell recognition GO:0009988 25 23 0,000 0,04995208 0,06603555 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04995208 0,06599929 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,04995208 0,06596306 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04995208 0,06592688 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04995208 0,06589074 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,05206723 0,06864315 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05206723 0,06860556 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05206723 0,06856801 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05206723 0,0685305 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05206723 0,06849303 ! vesicle docking GO:0048278 47 24 0,000 0,05206723 0,0684556 ! spinal cord development GO:0021510 47 24 0,000 0,05206723 0,06841821 ! vacuole organization GO:0007033 43 24 0,000 0,05206723 0,06838087 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05206723 0,06834356 ! digestive system process GO:0022600 39 24 0,000 0,05206723 0,0683063 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05206723 0,06826907 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05206723 0,06823189 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05206723 0,06819474 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05206723 0,06815764 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,05206723 0,06812058 ! membrane depolarization GO:0051899 39 24 0,000 0,05206723 0,06808356 ! pentose metabolic process GO:0019321 35 24 0,000 0,05206723 0,06804658 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05206723 0,06800963 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05206723 0,06797273 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05206723 0,06793587 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05206723 0,06789905 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05206723 0,06786227 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05206723 0,06782553 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05206723 0,06778882 ! regulation of amine transport GO:0051952 40 24 0,000 0,05206723 0,06775216 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05417773 0,07046034 ! myelination GO:0042552 45 25 0,000 0,05417773 0,07042227 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05417773 0,07038425 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05417773 0,07034626 ! phototransduction GO:0007602 33 25 0,000 0,05417773 0,07030832 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05417773 0,07027042 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,05417773 0,07023256 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,05417773 0,07019474 ! receptor metabolic process GO:0043112 46 25 0,000 0,05417773 0,07015696 ! chromosome condensation GO:0030261 45 25 0,000 0,05417773 0,07011922 ! osteoblast differentiation GO:0001649 60 25 0,000 0,05417773 0,07008152 ! neural crest cell development GO:0014032 54 25 0,000 0,05417773 0,07004386 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05417773 0,07000624 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05417773 0,06996867 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05417773 0,06993113 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05417773 0,06989363 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,05417773 0,06985618 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05417773 0,06981876 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,05417773 0,06978138 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05417773 0,06974405 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,05417773 0,06970675 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05417773 0,0696695 ! telomere organization GO:0032200 43 25 0,000 0,05417773 0,06963228 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05417773 0,0695951 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05417773 0,06955797 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05628361 0,07222313 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05628361 0,07218463 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05628361 0,07214617 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05628361 0,07210776 ! initiation of viral infection GO:0019059 57 26 0,000 0,05628361 0,07206938 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05628361 0,07203105 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05628361 0,07199275 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05628361 0,0719545 ! molting cycle process GO:0022404 50 26 0,000 0,05628361 0,07191629 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05628361 0,07187812 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,05628361 0,07183998 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,05628361 0,07180189 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,05628361 0,07176384 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,05628361 0,07172583 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,05628361 0,07168786 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,05628361 0,07164993 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,05628361 0,07161204 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05628361 0,07157419 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05628361 0,07153638 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,05628361 0,07149861 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05628361 0,07146088 ! blastocyst development GO:0001824 49 26 0,000 0,05628361 0,07142319 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05628361 0,07138554 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05628361 0,07134793 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05628361 0,07131036 ! neuron fate commitment GO:0048663 48 27 0,000 0,05838487 0,07393368 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,05838487 0,07389479 ! iron ion transport GO:0006826 59 27 0,000 0,05838487 0,07385594 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,05838487 0,07381713 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,05838487 0,07377836 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,05838487 0,07373963 ! fat cell differentiation GO:0045444 50 27 0,000 0,05838487 0,07370094 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,05838487 0,0736623 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,05838487 0,07362369 ! response to toxin GO:0009636 47 27 0,000 0,05838487 0,07358512 ! primary neural tube formation GO:0014020 51 27 0,000 0,05838487 0,0735466 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,05838487 0,07350811 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,05838487 0,07346967 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,05838487 0,07343126 ! glutathione metabolic process GO:0006749 39 27 0,000 0,05838487 0,07339289 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,05838487 0,07335457 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,05838487 0,07331628 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,05838487 0,07327804 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,05838487 0,07323983 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06048152 0,0758304 ! circadian rhythm GO:0007623 50 28 0,000 0,06048152 0,07579091 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06048152 0,07575145 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,06048152 0,07571204 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,06048152 0,07567267 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06048152 0,07563334 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06048152 0,07559405 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06048152 0,0755548 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,06048152 0,07551559 ! synaptogenesis GO:0007416 42 28 0,000 0,06048152 0,07547642 ! lipid oxidation GO:0034440 43 28 0,000 0,06048152 0,07543729 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,06048152 0,07539821 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,06048152 0,07535916 ! translational initiation GO:0006413 65 29 0,000 0,06257357 0,07792547 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,06257357 0,07788516 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06257357 0,07784489 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,06257357 0,07780466 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06257357 0,07776447 ! catechol metabolic process GO:0009712 54 29 0,000 0,06257357 0,07772432 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,06257357 0,07768422 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,06257357 0,07764416 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,06257357 0,07760413 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,06257357 0,07756415 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,06257357 0,07752421 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,06257357 0,07748431 ! cell fate determination GO:0001709 60 29 0,000 0,06257357 0,07744445 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06257357 0,07740464 ! detection of light stimulus GO:0009583 38 29 0,000 0,06257357 0,07736486 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,06257357 0,07732512 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,06257357 0,07728543 ! tissue homeostasis GO:0001894 48 29 0,000 0,06257357 0,07724578 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,06257357 0,07720616 ! phenol metabolic process GO:0018958 55 30 0,000 0,06466104 0,07974088 ! zinc ion transport GO:0006829 45 30 0,000 0,06466104 0,07970003 ! membrane docking GO:0022406 61 30 0,000 0,06466104 0,07965922 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,06466104 0,07961845 ! cell junction assembly GO:0034329 78 30 0,000 0,06466104 0,07957772 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06466104 0,07953704 ! acute-phase response GO:0006953 49 30 0,000 0,06466104 0,0794964 ! myofibril assembly GO:0030239 47 30 0,000 0,06466104 0,0794558 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06466104 0,07941524 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06466104 0,07937472 ! phospholipid transport GO:0015914 51 30 0,000 0,06466104 0,07933424 ! ensheathment of neurons GO:0007272 57 30 0,000 0,06466104 0,07929381 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06466104 0,07925341 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,06466104 0,07921306 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,06466104 0,07917275 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06466104 0,07913248 ! eye morphogenesis GO:0048592 60 30 0,000 0,06466104 0,07909225 ! regulation of B cell activation GO:0050864 50 30 0,000 0,06466104 0,07905206 ! response to heat GO:0009408 50 30 0,000 0,06466104 0,07901191 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06674392 0,08151567 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06674392 0,08147431 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06674392 0,081433 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06674392 0,08139172 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06674392 0,08135049 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06674392 0,0813093 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,06674392 0,08126815 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06674392 0,08122705 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,06674392 0,08118598 ! ovulation cycle process GO:0022602 49 31 0,000 0,06674392 0,08114496 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06674392 0,08110397 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,06674392 0,08106303 ! peptide transport GO:0015833 55 31 0,000 0,06674392 0,08102213 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,06674392 0,08098128 ! iron ion homeostasis GO:0055072 54 31 0,000 0,06674392 0,08094046 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,06674392 0,08089968 ! natural killer cell activation GO:0030101 45 31 0,000 0,06674392 0,08085895 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06674392 0,08081825 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06674392 0,0807776 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06674392 0,08073699 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06674392 0,08069642 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06674392 0,08065589 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06882223 0,08312565 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,06882223 0,08308394 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,06882223 0,08304227 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06882223 0,08300065 ! cholesterol transport GO:0030301 56 32 0,000 0,06882223 0,08295906 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06882223 0,08291752 ! spliceosome assembly GO:0000245 67 32 0,000 0,06882223 0,08287602 ! spindle organization GO:0007051 46 32 0,000 0,06882223 0,08283456 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,06882223 0,08279315 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,06882223 0,08275177 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,06882223 0,08271044 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,06882223 0,08266914 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,06882223 0,08262789 ! muscle cell development GO:0055001 49 32 0,000 0,06882223 0,08258668 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06882223 0,08254551 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,06882223 0,08250438 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06882223 0,08246329 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,06882223 0,08242225 ! ovulation cycle GO:0042698 51 32 0,000 0,06882223 0,08238124 ! peripheral nervous system development GO:0007422 64 32 0,000 0,06882223 0,08234028 ! BMP signaling pathway GO:0030509 64 32 0,000 0,06882223 0,08229935 ! hindbrain development GO:0030902 61 32 0,000 0,06882223 0,08225847 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06882223 0,08221762 ! gene silencing GO:0016458 65 32 0,000 0,06882223 0,08217682 ! post-embryonic development GO:0009791 69 33 0,000 0,07089599 0,08461099 ! protein targeting to membrane GO:0006612 68 33 0,000 0,07089599 0,08456904 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,07089599 0,08452713 ! ceramide metabolic process GO:0006672 64 33 0,000 0,07089599 0,08448526 ! cell fate specification GO:0001708 52 33 0,000 0,07089599 0,08444344 ! sterol transport GO:0015918 57 33 0,000 0,07089599 0,08440166 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,07089599 0,08435991 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,07089599 0,08431821 ! adult locomotory behavior GO:0008344 59 33 0,000 0,07089599 0,08427655 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,07089599 0,08423494 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,07089599 0,08419336 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,07296519 0,08660792 ! glial cell differentiation GO:0010001 63 34 0,000 0,07296519 0,08656521 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,07296519 0,08652255 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07296519 0,08647993 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07296519 0,08643735 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,07296519 0,08639481 ! mismatch repair GO:0006298 46 34 0,000 0,07296519 0,08635231 ! spermatid development GO:0007286 63 34 0,000 0,07296519 0,08630986 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,07296519 0,08626745 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07296519 0,08622508 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,07502986 0,08862142 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,07502986 0,08857794 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,07502986 0,0885345 ! female gonad development GO:0008585 58 35 0,000 0,07502986 0,0884911 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,07502986 0,08844774 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,07502986 0,08840443 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,07502986 0,08836116 ! neural tube formation GO:0001841 67 35 0,000 0,07502986 0,08831793 ! vesicle localization GO:0051648 64 35 0,000 0,07502986 0,08827474 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,07708999 0,09065422 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,07708999 0,09060993 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,07708999 0,09056569 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,07708999 0,09052149 ! cell junction organization GO:0034330 86 36 0,000 0,07708999 0,09047733 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,07708999 0,09043322 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,07708999 0,09038915 ! positive regulation of cell development GO:0010720 80 36 0,000 0,07708999 0,09034512 ! regulation of proteolysis GO:0030162 72 36 0,000 0,07708999 0,09030113 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,07708999 0,09025719 ! aerobic respiration GO:0009060 55 36 0,000 0,07708999 0,09021329 ! embryonic organ development GO:0048568 57 36 0,000 0,07708999 0,09016943 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,07708999 0,09012562 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,07708999 0,09008185 ! RNA export from nucleus GO:0006405 56 37 0,000 0,07914561 0,092439 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,07914561 0,09239415 ! meiosis I GO:0007127 65 37 0,000 0,07914561 0,09234934 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,07914561 0,09230457 ! sister chromatid segregation GO:0000819 58 37 0,000 0,07914561 0,09225985 ! actomyosin structure organization GO:0031032 62 37 0,000 0,07914561 0,09221518 ! organic anion transport GO:0015711 68 37 0,000 0,07914561 0,09217054 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,07914561 0,09212595 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,07914561 0,0920814 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,07914561 0,0920369 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,07914561 0,09199243 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,07914561 0,09194801 ! glycogen metabolic process GO:0005977 61 37 0,000 0,07914561 0,09190364 ! pigment metabolic process GO:0042440 80 37 0,000 0,07914561 0,0918593 ! spermatid differentiation GO:0048515 66 37 0,000 0,07914561 0,09181501 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,08119671 0,09414906 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,08119671 0,09410371 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,08119671 0,0940584 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,08119671 0,09401314 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,08119671 0,09396792 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,08119671 0,09392274 ! lipid homeostasis GO:0055088 67 38 0,000 0,08119671 0,09387761 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,08119671 0,09383251 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,08119671 0,09378747 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,08119671 0,09374246 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,08119671 0,0936975 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,08119671 0,09365259 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,08119671 0,09360771 ! glucan metabolic process GO:0044042 62 38 0,000 0,08119671 0,09356288 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,08324332 0,09587526 ! learning GO:0007612 77 39 0,000 0,08324332 0,09582939 ! ear morphogenesis GO:0042471 60 39 0,000 0,08324332 0,09578356 ! organic ether metabolic process GO:0018904 55 39 0,000 0,08324332 0,09573778 ! ion transmembrane transport GO:0034220 66 39 0,000 0,08324332 0,09569203 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,08324332 0,09564634 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,08324332 0,09560068 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,08324332 0,09555507 ! RNA modification GO:0009451 57 39 0,000 0,08324332 0,0955095 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,08324332 0,09546398 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,08528543 0,09775929 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,08528543 0,09771274 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08528543 0,09766623 ! feeding behavior GO:0007631 59 40 0,000 0,08528543 0,09761977 ! negative regulation of binding GO:0051100 72 40 0,000 0,08528543 0,09757335 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,08528543 0,09752697 ! mesenchymal cell development GO:0014031 87 40 0,000 0,08528543 0,09748064 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08528543 0,09743436 ! maintenance of protein location GO:0045185 91 40 0,000 0,08528543 0,09738811 ! cytokinesis GO:0000910 72 40 0,000 0,08528543 0,09734191 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08732307 0,09962034 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08732307 0,09957313 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08732307 0,09952596 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08732307 0,09947883 ! gliogenesis GO:0042063 88 41 0,000 0,08732307 0,09943175 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,08732307 0,09938472 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,08732307 0,09933773 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,08732307 0,09929078 ! female gamete generation GO:0007292 61 41 0,000 0,08732307 0,09924388 ! polyol metabolic process GO:0019751 66 41 0,000 0,08732307 0,09919702 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,08732307 0,09915021 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,08935623 0,10141089 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,08935623 0,10136308 ! regulation of tube size GO:0035150 71 42 0,000 0,08935623 0,10131531 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,08935623 0,10126758 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,08935623 0,10121991 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,08935623 0,10117227 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,08935623 0,10112469 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,08935623 0,10107714 ! neuron migration GO:0001764 79 42 0,000 0,08935623 0,10102964 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,09138493 0,10327484 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,09138493 0,10322635 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,09138493 0,10317791 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,09138493 0,10312952 ! glucose transport GO:0015758 65 43 0,000 0,09138493 0,10308117 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,09138493 0,10303286 ! neural tube development GO:0021915 77 43 0,000 0,09138493 0,10298461 ! striated muscle contraction GO:0006941 77 43 0,000 0,09138493 0,10293639 ! phagocytosis GO:0006909 90 43 0,000 0,09138493 0,10288822 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,09138493 0,1028401 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,09340917 0,10506894 ! hexose transport GO:0008645 67 44 0,000 0,09340917 0,10501985 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,09340917 0,10497079 ! biopolymer methylation GO:0043414 84 44 0,000 0,09340917 0,10492179 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,09340917 0,10487283 ! developmental growth GO:0048589 82 44 0,000 0,09340917 0,10482391 ! maintenance of location in cell GO:0051651 97 44 0,000 0,09340917 0,10477505 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09542898 0,10699074 ! glycolysis GO:0006096 65 45 0,000 0,09542898 0,1069409 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,09542898 0,10689112 ! leukocyte migration GO:0050900 68 45 0,000 0,09542898 0,10684138 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,09542898 0,10679168 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,09542898 0,10674204 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09542898 0,10669244 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09542898 0,10664288 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09542898 0,10659337 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09542898 0,10654391 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,09744435 0,10874356 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,09744435 0,10869314 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,09744435 0,10864277 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,09744435 0,10859245 ! positive regulation of defense response GO:0031349 76 47 0,000 0,0994553 0,11078215 ! response to calcium ion GO:0051592 81 47 0,000 0,0994553 0,11073089 ! endosome transport GO:0016197 108 47 0,000 0,0994553 0,11067967 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,0994553 0,1106285 ! JNK cascade GO:0007254 91 47 0,000 0,0994553 0,11057738 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,0994553 0,1105263 ! methylation GO:0032259 90 47 0,000 0,0994553 0,11047528 ! protein homooligomerization GO:0051260 76 47 0,000 0,0994553 0,1104243 ! Notch signaling pathway GO:0007219 96 48 0,000 0,10146183 0,11260017 ! cellular component disassembly GO:0022411 86 48 0,000 0,10146183 0,11254826 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,10146183 0,11249639 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,10146183 0,11244457 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,10146183 0,1123928 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,10146183 0,11234108 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,10146183 0,11228941 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,10146183 0,11223778 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,10346396 0,11439995 ! regulation of action potential GO:0001508 95 49 0,000 0,10346396 0,1143474 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,10346396 0,1142949 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,10346396 0,11424245 ! regulation of ion transport GO:0043269 77 49 0,000 0,10346396 0,11419004 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,10346396 0,11413769 ! peptide metabolic process GO:0006518 76 49 0,000 0,10346396 0,11408538 ! response to temperature stimulus GO:0009266 76 49 0,000 0,10346396 0,11403312 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,10346396 0,1139809 ! endocrine system development GO:0035270 104 49 0,000 0,10346396 0,11392874 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,10346396 0,11387662 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,10346396 0,11382455 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,10346396 0,11377253 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,10346396 0,11372056 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,1054617 0,1158634 ! neuromuscular process GO:0050905 99 50 0,000 0,1054617 0,11581052 ! regulation of ossification GO:0030278 117 50 0,000 0,1054617 0,11575769 ! inner ear development GO:0048839 79 50 0,000 0,1054617 0,1157049 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,1054617 0,11565216 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,1054617 0,11559947 ! viral infectious cycle GO:0019058 99 51 0,000 0,10745505 0,11773081 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,10745505 0,11767722 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,10745505 0,11762368 ! excretion GO:0007588 83 51 0,000 0,10745505 0,11757019 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,10745505 0,11751675 ! chromatin remodeling GO:0006338 109 51 0,000 0,10745505 0,11746336 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,10745505 0,11741001 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,10745505 0,11735672 ! vesicle organization GO:0016050 107 51 0,000 0,10745505 0,11730347 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,10745505 0,11725027 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,10745505 0,11719712 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,10944402 0,11931233 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,10944402 0,1192583 ! membrane fusion GO:0006944 110 52 0,000 0,10944402 0,11920431 ! amino acid activation GO:0043038 92 52 0,000 0,10944402 0,11915037 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,10944402 0,11909648 ! synapse organization GO:0050808 85 52 0,000 0,10944402 0,11904264 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,11142863 0,12114654 ! RNA catabolic process GO:0006401 93 53 0,000 0,11142863 0,12109182 ! regulation of translational initiation GO:0006446 82 53 0,000 0,11142863 0,12103715 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,11142863 0,12098253 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,11142863 0,12092796 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,11142863 0,12087344 ! cell maturation GO:0048469 100 53 0,000 0,11142863 0,12081897 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,11142863 0,12076454 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,11340888 0,12285537 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,11340888 0,12280008 ! cell recognition GO:0008037 85 54 0,000 0,11340888 0,12274484 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,11340888 0,12268965 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,11340888 0,12263451 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,11340888 0,12257941 ! chloride transport GO:0006821 90 55 0,000 0,11538479 0,12465909 ! glucose catabolic process GO:0006007 82 55 0,000 0,11538479 0,12460314 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,11538479 0,12454724 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,11538479 0,12449139 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,11538479 0,12443559 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,11538479 0,12437984 ! RNA elongation GO:0006354 79 55 0,000 0,11538479 0,12432414 ! nuclear export GO:0051168 97 55 0,000 0,11538479 0,12426849 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,11538479 0,12421289 ! regulation of actin filament length GO:0030832 105 56 0,000 0,11735635 0,1262788 ! sensory perception of smell GO:0007608 80 56 0,000 0,11735635 0,12622235 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,11735635 0,12616595 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,11735635 0,1261096 ! proton transport GO:0015992 94 56 0,000 0,11735635 0,1260533 ! muscle fiber development GO:0048747 112 57 0,000 0,11932359 0,12810913 ! lipid modification GO:0030258 97 57 0,000 0,11932359 0,12805199 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,11932359 0,1279949 ! maintenance of location GO:0051235 118 57 0,000 0,11932359 0,12793786 ! hydrogen transport GO:0006818 97 58 0,000 0,12128651 0,12998456 ! regulation of endocytosis GO:0030100 91 58 0,000 0,12128651 0,12992669 ! adult behavior GO:0030534 99 58 0,000 0,12128651 0,12986887 ! regulation of cellular component size GO:0032535 109 59 0,000 0,12324512 0,13190736 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,12324512 0,13184871 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,12324512 0,13179011 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,12324512 0,13173157 ! DNA catabolic process GO:0006308 86 59 0,000 0,12324512 0,13167307 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,12324512 0,13161463 ! establishment of organelle localization GO:0051656 109 59 0,000 0,12324512 0,13155623 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,12519943 0,13358307 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,12519943 0,13352386 ! regulation of heart contraction GO:0008016 110 60 0,000 0,12519943 0,1334647 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,12519943 0,13340559 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,12714944 0,13542344 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,12714944 0,13536352 ! tRNA processing GO:0008033 89 61 0,000 0,12714944 0,13530365 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,12714944 0,13524384 ! ear development GO:0043583 103 62 0,000 0,12909518 0,13725276 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,12909518 0,13719213 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,13103664 0,13919388 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,13103664 0,13913246 ! detection of external stimulus GO:0009581 91 63 0,000 0,13103664 0,13907108 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,13103664 0,13900977 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,13297384 0,14100267 ! cell redox homeostasis GO:0045454 102 64 0,000 0,13297384 0,14094055 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,13297384 0,14087849 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,13297384 0,14081648 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,13297384 0,14075453 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,13490678 0,14273778 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,13490678 0,14267504 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,13490678 0,14261235 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,13683548 0,14458768 ! actin filament organization GO:0007015 148 66 0,000 0,13683548 0,14452421 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,13683548 0,1444608 ! extracellular matrix organization GO:0030198 133 66 0,000 0,13683548 0,14439744 ! secondary metabolic process GO:0019748 116 66 0,000 0,13683548 0,14433413 ! developmental maturation GO:0021700 116 66 0,000 0,13683548 0,14427088 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,13875994 0,14623584 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,13875994 0,14617181 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,13875994 0,14610784 ! chromosome segregation GO:0007059 113 67 0,000 0,13875994 0,14604393 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,13875994 0,14598007 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,13875994 0,14591627 ! hexose catabolic process GO:0019320 104 67 0,000 0,13875994 0,14585252 ! activation of immune response GO:0002253 105 67 0,000 0,13875994 0,14578883 ! amino acid transport GO:0006865 125 68 0,000 0,14068018 0,14774182 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,14068018 0,14767736 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,14068018 0,14761295 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,14068018 0,14754861 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,14068018 0,14748431 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,14068018 0,14742008 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,14259619 0,14936284 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,14259619 0,14929784 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,14259619 0,1492329 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,14259619 0,14916802 ! antigen processing and presentation GO:0019882 104 69 0,000 0,14259619 0,14910319 ! amine catabolic process GO:0009310 117 71 0,000 0,14641561 0,15303039 ! humoral immune response GO:0006959 109 71 0,000 0,14641561 0,15296395 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,14641561 0,15289755 ! regulation of immune effector process GO:0002697 137 71 0,000 0,14641561 0,15283122 ! acute inflammatory response GO:0002526 113 72 0,000 0,14831903 0,15475091 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,14831903 0,15468383 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,14831903 0,15461681 ! carbohydrate transport GO:0008643 110 72 0,000 0,14831903 0,15454985 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,14831903 0,15448294 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,14831903 0,15441609 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,14831903 0,15434931 ! learning or memory GO:0007611 147 73 0,000 0,15021827 0,15625818 ! regulation of blood pressure GO:0008217 125 73 0,000 0,15021827 0,15619065 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,15021827 0,15612318 ! fertilization GO:0009566 90 73 0,000 0,15021827 0,15605577 ! transition metal ion transport GO:0000041 126 74 0,000 0,15211334 0,15795628 ! neurotransmitter transport GO:0006836 123 74 0,000 0,15211334 0,15788813 ! meiosis GO:0007126 121 74 0,000 0,15211334 0,15782005 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,15211334 0,15775202 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,15211334 0,15768406 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,15211334 0,15761615 ! organelle localization GO:0051640 136 74 0,000 0,15211334 0,1575483 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,15400424 0,15943813 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,15400424 0,15936955 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,15400424 0,15930103 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,15400424 0,15923258 ! meiotic cell cycle GO:0051321 122 75 0,000 0,15400424 0,15916418 ! rhythmic process GO:0048511 128 75 0,000 0,15400424 0,15909584 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,15589099 0,16097585 ! defense response to bacterium GO:0042742 89 76 0,000 0,15589099 0,16090679 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,15589099 0,16083779 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,15589099 0,16076885 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,15777359 0,16264065 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,15777359 0,16257099 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,15777359 0,1625014 ! blood coagulation GO:0007596 146 78 0,000 0,15965206 0,16436579 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,15965206 0,16429549 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,15965206 0,16422525 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,1615264 0,16608228 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,1615264 0,16601133 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,1615264 0,16594045 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,1615264 0,16586962 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,16339662 0,16771855 ! response to metal ion GO:0010038 140 80 0,000 0,16339662 0,16764703 ! muscle cell differentiation GO:0042692 159 80 0,000 0,16339662 0,16757557 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,16339662 0,16750417 ! inorganic anion transport GO:0015698 138 80 0,000 0,16339662 0,16743283 ! digestion GO:0007586 112 81 0,000 0,16526274 0,16927294 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,16526274 0,16920091 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,16526274 0,16912894 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,16526274 0,16905703 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,16712475 0,17088914 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,16712475 0,17081655 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,16712475 0,17074401 ! regulation of lyase activity GO:0051339 160 83 0,000 0,16898267 0,17256889 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,17083651 0,17438805 ! hemostasis GO:0007599 158 84 0,000 0,17083651 0,1743141 ! regulation of ligase activity GO:0051340 142 84 0,000 0,17083651 0,1742402 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,17083651 0,17416637 ! response to unfolded protein GO:0006986 131 85 0,000 0,17268627 0,17597762 ! nucleosome assembly GO:0006334 122 85 0,000 0,17268627 0,17590312 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,17268627 0,17582868 ! amine biosynthetic process GO:0009309 138 86 0,000 0,17453197 0,17763279 ! response to inorganic substance GO:0010035 153 86 0,000 0,17453197 0,17755768 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,17453197 0,17748264 ! chromatin assembly GO:0031497 124 86 0,000 0,17453197 0,17740766 ! alcohol catabolic process GO:0046164 130 86 0,000 0,17453197 0,17733274 ! amine transport GO:0015837 155 86 0,000 0,17453197 0,17725788 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,17637361 0,1790527 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,17637361 0,17897719 ! cellular respiration GO:0045333 135 88 0,000 0,17821121 0,18076567 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,17821121 0,18068949 ! regulation of neurological system process GO:0031644 148 88 0,000 0,17821121 0,18061338 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,17821121 0,18053733 ! cellular defense response GO:0006968 114 89 0,000 0,18004476 0,18231806 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,18004476 0,18224135 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,18187429 0,18401579 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,18187429 0,18393844 ! sterol metabolic process GO:0016125 152 91 0,000 0,18369979 0,1857066 ! response to protein stimulus GO:0051789 149 91 0,000 0,18369979 0,1856286 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,18369979 0,18555067 ! regulation of defense response GO:0031347 149 92 0,000 0,18552128 0,18731188 ! nucleosome organization GO:0034728 138 92 0,000 0,18552128 0,18723331 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,18552128 0,18715481 ! vitamin metabolic process GO:0006766 139 92 0,000 0,18552128 0,18707637 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,18733877 0,18882995 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,18733877 0,18875087 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,18733877 0,18867187 ! regulation of membrane potential GO:0042391 164 93 0,000 0,18733877 0,18859292 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,18915227 0,19033892 ! female pregnancy GO:0007565 164 94 0,000 0,18915227 0,19025934 ! transcription initiation GO:0006352 153 94 0,000 0,18915227 0,19017984 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,19096177 0,19191897 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,1927673 0,19365266 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,1927673 0,19357184 ! positive regulation of immune response GO:0050778 156 96 0,000 0,1927673 0,19349108 ! detection of stimulus GO:0051606 151 96 0,000 0,1927673 0,19341039 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,19456886 0,19513659 ! protein ubiquitination GO:0016567 217 97 0,000 0,19456886 0,19505528 ! hormone metabolic process GO:0042445 157 97 0,000 0,19456886 0,19497404 ! response to virus GO:0009615 160 98 0,000 0,19636646 0,19669346 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,19636646 0,19661161 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,19636646 0,19652982 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,1981601 0,1982425 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,1981601 0,1981601