pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/10-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 3,000 1,401E-09 3,37E-06 ! BMP signaling pathway GO:0030509 64 32 3,000 2,335E-07 2,809E-04 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 3,000 7,907E-07 6,341E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 1,932E-06 1,162E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 4,811E-06 2,315E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 6,484E-06 2,6E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 3,000 9,212E-06 3,166E-03 ! cell fate determination GO:0001709 60 29 2,000 1,526E-05 4,59E-03 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 2,000 1,694E-05 4,528E-03 ! transcription initiation GO:0006352 153 94 3,000 1,836E-05 4,417E-03 ! hindbrain development GO:0030902 61 32 2,000 2,064E-05 4,515E-03 ! glial cell fate commitment GO:0021781 13 5 1,000 2,693E-05 5,399E-03 ! protein maturation by protein folding GO:0022417 13 5 1,000 2,693E-05 4,983E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 2,958E-05 5,083E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 3,215E-05 5,157E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 4,035E-05 6,067E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! mesenchymal cell development GO:0014031 87 40 2,000 4,074E-05 5,765E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of intracellular protein transport GO:0033157 80 42 2,000 4,722E-05 6,312E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,642E-05 7,145E-03 ! establishment of tissue polarity GO:0007164 8 7 1,000 5,642E-05 6,788E-03 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 1,000 5,642E-05 6,465E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 6,215E-05 6,797E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 6,215E-05 6,501E-03 ! ER overload response GO:0006983 12 8 1,000 7,515E-05 7,534E-03 ! blastocyst growth GO:0001832 19 8 1,000 7,515E-05 7,233E-03 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 2,000 8,476E-05 7,844E-03 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 9,652E-05 8,601E-03 ! RNA elongation GO:0006354 79 55 2,000 1,063E-04 9,133E-03 ! regulation of intracellular transport GO:0032386 101 57 2,000 1,183E-04 9,812E-03 ! midbrain development GO:0030901 13 10 1,000 1,205E-04 9,666E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 1,000 1,472E-04 0,01142089 GO:0046579|positive regulation of Ras protein signal transduction, ! nucleosome positioning GO:0016584 15 11 1,000 1,472E-04 0,01106399 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 1,594E-04 0,01162078 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,764E-04 0,01248253 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 2E-04 0,01374712 ! chromatin silencing GO:0006342 26 13 1,000 2,082E-04 0,01391774 ! stem cell development GO:0048864 43 14 1,000 2,427E-04 0,01578174 GO:0019827|stem cell maintenance, ! embryonic hindlimb morphogenesis GO:0035116 33 15 1,000 2,797E-04 0,01771169 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 3E-04 0,01851051 ! activation of protein kinase activity GO:0032147 147 79 2,000 3,115E-04 0,01873828 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,194E-04 0,0187409 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 3,616E-04 0,02071198 ! epidermis morphogenesis GO:0048730 40 18 1,000 4,063E-04 0,02273496 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 4,063E-04 0,02221825 ! regulation of protein transport GO:0051223 154 87 2,000 4,137E-04 0,02211817 GO:0070201|regulation of establishment of protein localization, ! stem cell differentiation GO:0048863 53 20 1,000 5,035E-04 0,02633571 ! peptidyl-serine modification GO:0018209 43 20 1,000 5,035E-04 0,02577538 ! hindlimb morphogenesis GO:0035137 43 21 1,000 5,559E-04 0,02786548 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 5,559E-04 0,0272968 ! regulation of protein localization GO:0032880 176 97 2,000 5,688E-04 0,027369 ! protein amino acid alkylation GO:0008213 53 25 1,000 7,908E-04 0,03730756 GO:0006479|protein amino acid methylation, ! osteoblast differentiation GO:0001649 60 25 1,000 7,908E-04 0,0365901 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 7,908E-04 0,03589972 ! embryonic pattern specification GO:0009880 44 26 1,000 8,558E-04 0,0381307 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 8,558E-04 0,03743741 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 8,558E-04 0,03676889 ! blastocyst development GO:0001824 49 26 1,000 8,558E-04 0,03612382 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 9,933E-04 0,04120292 ! mesoderm formation GO:0001707 69 31 1,000 1,218E-03 0,04966884 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 1,298E-03 0,05204191 ! gene silencing GO:0016458 65 32 1,000 1,298E-03 0,05118876 ! formation of primary germ layer GO:0001704 72 33 1,000 1,38E-03 0,05355559 ! glial cell differentiation GO:0010001 63 34 1,000 1,465E-03 0,05594029 ! mesoderm morphogenesis GO:0048332 76 34 1,000 1,465E-03 0,05506622 ! glycogen metabolic process GO:0005977 61 37 1,000 1,733E-03 0,06416277 ! glucan metabolic process GO:0044042 62 38 1,000 1,828E-03 0,06663059 GO:0006073|cellular glucan metabolic process, ! response to xenobiotic stimulus GO:0009410 57 39 1,000 1,925E-03 0,06911077 ! gliogenesis GO:0042063 88 41 1,000 2,125E-03 0,07519476 ! keratinocyte differentiation GO:0030216 62 41 1,000 2,125E-03 0,07410498 ! epithelial cell differentiation GO:0030855 79 43 1,000 2,335E-03 0,08026993 ! energy reserve metabolic process GO:0006112 74 43 1,000 2,335E-03 0,07913937 ! biopolymer methylation GO:0043414 84 44 1,000 2,444E-03 0,08166993 ! developmental growth GO:0048589 82 44 1,000 2,444E-03 0,08055116 ! cell growth GO:0016049 84 45 1,000 2,555E-03 0,08307061 ! epidermal cell differentiation GO:0009913 68 46 1,000 2,668E-03 0,08559797 ! methylation GO:0032259 90 47 1,000 2,784E-03 0,08813267 ! protein homooligomerization GO:0051260 76 47 1,000 2,784E-03 0,08698809 ! Notch signaling pathway GO:0007219 96 48 1,000 2,902E-03 0,08951172 ! regulation of ossification GO:0030278 117 50 1,000 3,145E-03 0,09577576 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 3,145E-03 0,09457857 ! chromatin remodeling GO:0006338 109 51 1,000 3,27E-03 0,09712085 ! covalent chromatin modification GO:0016569 101 52 1,000 3,397E-03 0,09966846 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 3,792E-03 0,10992563 ! gastrulation GO:0007369 112 55 1,000 3,792E-03 0,10861699 ! regulation of bone remodeling GO:0046850 137 57 1,000 4,067E-03 0,11511887 ! regulation of tissue remodeling GO:0034103 140 58 1,000 4,208E-03 0,11771939 ! mesoderm development GO:0007498 119 61 1,000 4,644E-03 0,12841889 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 5,256E-03 0,14369547 GO:0035113|embryonic appendage morphogenesis, ! appendage morphogenesis GO:0035107 135 70 1,000 6,07E-03 0,16409575 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 6,239E-03 0,16679991 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 122 72 1,000 6,411E-03 0,16950135 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 6,76E-03 0,1767967 ! protein oligomerization GO:0051259 139 78 1,000 7,485E-03 0,19363228 ! regulation of peptidase activity GO:0052547 134 79 1,000 7,671E-03 0,19634116 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 8,274E-03 0,2095497 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 8,274E-03 0,20736689 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 8,274E-03 0,20522909 ! positive regulation of helicase activity GO:0051096 11 5 0,000 8,274E-03 0,20313491 ! neuron fate determination GO:0048664 7 5 0,000 8,274E-03 0,20108304 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,274E-03 0,19907221 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 8,274E-03 0,1971012 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 8,274E-03 0,19516884 ! polyol transport GO:0015791 12 5 0,000 8,274E-03 0,19327399 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 8,274E-03 0,19141559 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 8,274E-03 0,18959258 ! response to superoxide GO:0000303 10 5 0,000 8,274E-03 0,18780398 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,274E-03 0,1860488 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 8,274E-03 0,18432612 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 8,274E-03 0,18263506 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 8,274E-03 0,18097474 ! female meiosis GO:0007143 7 5 0,000 8,274E-03 0,17934434 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 8,274E-03 0,17774305 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 8,274E-03 0,1761701 ! cobalt ion transport GO:0006824 11 5 0,000 8,274E-03 0,17462475 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 8,274E-03 0,17310627 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 8,274E-03 0,17161398 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 8,274E-03 0,17014719 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 8,274E-03 0,16870527 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 8,274E-03 0,16728757 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 8,274E-03 0,16589351 ! embryonic camera-type eye development GO:0031076 10 5 0,000 8,274E-03 0,16452249 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 8,274E-03 0,16317395 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 8,274E-03 0,16184733 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 8,274E-03 0,16054211 ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,274E-03 0,15925777 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,274E-03 0,15799382 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,274E-03 0,15674977 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 8,274E-03 0,15552517 ! negative chemotaxis GO:0050919 14 5 0,000 8,274E-03 0,15431955 ! positive regulation of histone modification GO:0031058 5 5 0,000 8,274E-03 0,15313247 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 8,274E-03 0,15196352 ! sensory perception of bitter taste GO:0050913 7 5 0,000 8,274E-03 0,15081228 ! behavioral response to pain GO:0048266 9 5 0,000 8,274E-03 0,14967836 ! clathrin coat assembly GO:0048268 14 5 0,000 8,274E-03 0,14856135 ! Notch receptor processing GO:0007220 8 5 0,000 8,274E-03 0,1474609 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,274E-03 0,14637663 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 8,274E-03 0,14530819 ! micturition GO:0060073 9 5 0,000 8,274E-03 0,14425523 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 8,274E-03 0,14321742 ! copulation GO:0007620 9 5 0,000 8,274E-03 0,14219444 ! spermidine metabolic process GO:0008216 7 5 0,000 8,274E-03 0,14118597 ! regulation of potassium ion transport GO:0043266 10 5 0,000 8,274E-03 0,1401917 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 8,274E-03 0,13921134 ! apoptotic cell clearance GO:0043277 20 5 0,000 8,274E-03 0,13824459 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 8,274E-03 0,13729118 ! lipoprotein particle clearance GO:0034381 10 5 0,000 8,274E-03 0,13635083 ! grooming behavior GO:0007625 6 5 0,000 8,274E-03 0,13542327 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 8,274E-03 0,13450825 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 8,274E-03 0,13360551 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,274E-03 0,13271481 ! response to protozoan GO:0001562 10 5 0,000 8,274E-03 0,1318359 ! positive regulation of glycolysis GO:0045821 14 5 0,000 8,274E-03 0,13096856 ! lymph vessel development GO:0001945 10 5 0,000 8,274E-03 0,13011256 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 8,274E-03 0,12926767 ! endochondral ossification GO:0001958 16 5 0,000 8,274E-03 0,12843369 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 8,274E-03 0,12761039 ! parathyroid gland development GO:0060017 13 5 0,000 8,274E-03 0,12679759 ! anagen GO:0042640 6 5 0,000 8,274E-03 0,12599507 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 8,274E-03 0,12520265 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 8,274E-03 0,12442013 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 8,274E-03 0,12364734 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 8,274E-03 0,12288408 ! dorsal spinal cord development GO:0021516 7 5 0,000 8,274E-03 0,12213019 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 8,274E-03 0,1213855 ! sphingoid catabolic process GO:0046521 6 5 0,000 8,274E-03 0,12064983 ! skeletal myofibril assembly GO:0014866 10 5 0,000 8,274E-03 0,11992302 ! smooth muscle tissue development GO:0048745 28 5 0,000 8,274E-03 0,11920492 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 8,274E-03 0,11849537 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 8,274E-03 0,11779421 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 8,274E-03 0,1171013 ! cardiac muscle fiber development GO:0048739 10 5 0,000 8,274E-03 0,1164165 ! transepithelial chloride transport GO:0030321 9 5 0,000 8,274E-03 0,11573966 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 8,274E-03 0,11507064 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 8,274E-03 0,11440932 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 8,274E-03 0,11375555 ! neutrophil mediated immunity GO:0002446 7 5 0,000 8,274E-03 0,11310921 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 8,274E-03 0,11247018 ! histidine catabolic process GO:0006548 6 5 0,000 8,274E-03 0,11183832 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 8,274E-03 0,11121353 ! microvillus organization GO:0032528 7 5 0,000 8,274E-03 0,11059567 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 8,274E-03 0,10998465 ! L-serine biosynthetic process GO:0006564 6 5 0,000 8,274E-03 0,10938034 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,274E-03 0,10878263 ! tryptophan metabolic process GO:0006568 9 5 0,000 8,274E-03 0,10819142 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 8,274E-03 0,1076066 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 8,274E-03 0,10702807 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 8,274E-03 0,10645573 ! polyol catabolic process GO:0046174 7 5 0,000 8,274E-03 0,10588948 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 8,274E-03 0,10532921 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 8,274E-03 0,10477485 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,274E-03 0,10422629 ! muscle cell migration GO:0014812 8 5 0,000 8,274E-03 0,10368344 ! mitochondrial fission GO:0000266 8 5 0,000 8,274E-03 0,10314622 ! sister chromatid cohesion GO:0007062 12 5 0,000 8,274E-03 0,10261454 ! mRNA transcription GO:0009299 9 5 0,000 8,274E-03 0,10208831 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 8,274E-03 0,10156746 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 8,274E-03 0,10105189 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 8,274E-03 0,10054152 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 8,274E-03 0,10003629 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 8,274E-03 0,09953611 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 8,274E-03 0,0990409 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 8,274E-03 0,0985506 ! response to food GO:0032094 6 5 0,000 8,274E-03 0,09806513 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 8,274E-03 0,09758442 ! positive regulation of transporter activity GO:0032411 8 5 0,000 8,274E-03 0,0971084 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 8,274E-03 0,096637 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,274E-03 0,09617015 ! paraxial mesoderm development GO:0048339 14 5 0,000 8,274E-03 0,09570779 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 8,274E-03 0,09524986 ! forebrain neuron development GO:0021884 13 5 0,000 8,274E-03 0,09479629 ! lipoprotein catabolic process GO:0042159 11 5 0,000 8,274E-03 0,09434702 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 8,274E-03 0,09390199 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 8,274E-03 0,09346113 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,274E-03 0,0930244 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 8,274E-03 0,09259173 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 8,274E-03 0,09216306 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,274E-03 0,09173835 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 8,274E-03 0,09131753 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 8,274E-03 0,09090055 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,274E-03 0,09048737 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 8,274E-03 0,09007792 ! basic amino acid transport GO:0015802 11 5 0,000 8,274E-03 0,08967217 ! cellular glucose homeostasis GO:0001678 5 5 0,000 8,274E-03 0,08927005 ! early endosome to late endosome transport GO:0045022 12 5 0,000 8,274E-03 0,08887152 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,274E-03 0,08847654 ! depyrimidination GO:0045008 10 5 0,000 8,274E-03 0,08808505 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 8,274E-03 0,08769701 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,274E-03 0,08731237 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 8,274E-03 0,0869311 ! zinc ion homeostasis GO:0055069 8 5 0,000 8,274E-03 0,08655314 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 8,274E-03 0,08617845 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 8,274E-03 0,08580699 ! forebrain morphogenesis GO:0048853 13 5 0,000 8,274E-03 0,08543872 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 8,274E-03 0,0850736 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 8,274E-03 0,08471158 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 8,274E-03 0,08435263 ! peptidyl-arginine modification GO:0018195 9 5 0,000 8,274E-03 0,08399671 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 8,274E-03 0,08364379 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,274E-03 0,08329381 ! response to arsenic GO:0046685 10 5 0,000 8,274E-03 0,08294676 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 8,274E-03 0,08260258 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 8,274E-03 0,08226125 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 8,274E-03 0,08192272 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 8,274E-03 0,08158697 ! response to cadmium ion GO:0046686 7 5 0,000 8,274E-03 0,08125396 ! bile acid biosynthetic process GO:0006699 6 5 0,000 8,274E-03 0,08092366 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 8,274E-03 0,08059604 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 8,274E-03 0,08027105 ! decidualization GO:0046697 11 5 0,000 8,274E-03 0,07994868 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 8,274E-03 0,07962889 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 8,274E-03 0,07931164 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 8,274E-03 0,07899691 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 8,274E-03 0,07868467 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 8,274E-03 0,07837489 ! base conversion or substitution editing GO:0016553 5 5 0,000 8,274E-03 0,07806753 ! neural tube patterning GO:0021532 7 5 0,000 8,274E-03 0,07776258 ! embryonic cleavage GO:0040016 6 5 0,000 8,274E-03 0,07746001 ! peroxisome fission GO:0016559 5 5 0,000 8,274E-03 0,07715977 ! histone demethylation GO:0016577 10 5 0,000 8,274E-03 0,07686186 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 8,274E-03 0,07656624 ! mitotic recombination GO:0006312 9 5 0,000 8,274E-03 0,07627288 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 8,274E-03 0,07598176 ! metaphase plate congression GO:0051310 7 5 0,000 8,274E-03 0,07569286 ! regulation of sterol transport GO:0032371 7 5 0,000 8,274E-03 0,07540614 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 8,274E-03 0,07512159 ! enteric nervous system development GO:0048484 8 5 0,000 8,274E-03 0,07483918 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 8,274E-03 0,07455888 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 8,274E-03 0,07428068 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 8,274E-03 0,07400454 ! muscle cell proliferation GO:0033002 11 5 0,000 8,274E-03 0,07373045 ! skeletal muscle regeneration GO:0043403 8 5 0,000 8,274E-03 0,07345838 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 8,274E-03 0,07318831 ! plasminogen activation GO:0031639 5 5 0,000 8,274E-03 0,07292022 ! B cell homeostasis GO:0001782 13 5 0,000 8,274E-03 0,07265409 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 8,274E-03 0,0723899 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 8,274E-03 0,07212761 ! metaphase GO:0051323 8 5 0,000 8,274E-03 0,07186723 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 8,274E-03 0,07160871 ! cellular response to nutrient GO:0031670 8 5 0,000 8,274E-03 0,07135205 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 8,274E-03 0,07109722 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 8,274E-03 0,0708442 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 8,274E-03 0,07059298 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 8,274E-03 0,07034354 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 8,274E-03 0,07009585 ! response to redox state GO:0051775 5 5 0,000 8,274E-03 0,0698499 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 8,274E-03 0,06960567 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 8,274E-03 0,06936314 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 8,274E-03 0,0691223 ! regulation of telomerase activity GO:0051972 6 5 0,000 8,274E-03 0,06888312 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,274E-03 0,06864559 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 8,274E-03 0,0684097 ! porphyrin catabolic process GO:0006787 12 5 0,000 8,274E-03 0,06817542 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 8,274E-03 0,06794274 ! striatum development GO:0021756 9 5 0,000 8,274E-03 0,06771164 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 8,274E-03 0,06748211 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 8,274E-03 0,06725413 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 8,274E-03 0,06702768 ! glial cell migration GO:0008347 11 5 0,000 8,274E-03 0,06680276 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 8,274E-03 0,06657934 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 8,274E-03 0,0663574 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 8,274E-03 0,06613695 ! somatic stem cell maintenance GO:0035019 15 5 0,000 8,274E-03 0,06591795 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 8,274E-03 0,0657004 ! negative regulation of lipase activity GO:0060192 8 5 0,000 8,274E-03 0,06548428 ! neuroprotection GO:0043526 6 5 0,000 8,274E-03 0,06526958 ! neural plate development GO:0001840 8 5 0,000 8,274E-03 0,06505628 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 8,274E-03 0,06484437 ! regulation of sensory perception GO:0051931 7 5 0,000 8,274E-03 0,06463384 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 8,274E-03 0,06442466 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 8,274E-03 0,06421684 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 8,274E-03 0,06401036 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 8,274E-03 0,0638052 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 8,274E-03 0,06360135 ! sequestering of calcium ion GO:0051208 7 5 0,000 8,274E-03 0,06339879 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,274E-03 0,06319753 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 8,274E-03 0,06299754 ! spindle assembly GO:0051225 6 5 0,000 8,274E-03 0,06279881 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 8,274E-03 0,06260133 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 8,274E-03 0,06240508 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 8,274E-03 0,06221007 ! drug metabolic process GO:0017144 6 5 0,000 8,274E-03 0,06201627 ! stem cell division GO:0017145 11 5 0,000 8,274E-03 0,06182367 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 8,274E-03 0,06163226 ! organ regeneration GO:0031100 7 5 0,000 8,274E-03 0,06144204 ! carnitine metabolic process GO:0009437 7 5 0,000 8,274E-03 0,06125299 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 8,274E-03 0,0610651 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 8,274E-03 0,06087835 ! nucleosome assembly GO:0006334 122 85 1,000 8,832E-03 0,06478817 ! one-carbon metabolic process GO:0006730 154 85 1,000 8,832E-03 0,06459125 ! chromatin assembly GO:0031497 124 86 1,000 9,033E-03 0,06585933 ! ossification GO:0001503 188 90 1,000 9,856E-03 0,07164548 ! protein-DNA complex assembly GO:0065004 130 90 1,000 9,856E-03 0,07142969 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 9,921E-03 0,07167943 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 9,921E-03 0,07146482 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 9,921E-03 0,0712515 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,921E-03 0,07103944 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 9,921E-03 0,07082864 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 9,921E-03 0,07061909 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 9,921E-03 0,07041077 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 9,921E-03 0,07020368 ! sleep GO:0030431 13 6 0,000 9,921E-03 0,0699978 ! response to oxygen radical GO:0000305 11 6 0,000 9,921E-03 0,06979313 ! positive regulation of axon extension GO:0045773 11 6 0,000 9,921E-03 0,06958965 ! myoblast cell fate commitment GO:0048625 16 6 0,000 9,921E-03 0,06938736 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 9,921E-03 0,06918624 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 9,921E-03 0,06898627 ! regulation of interferon-beta production GO:0032648 8 6 0,000 9,921E-03 0,06878747 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 9,921E-03 0,0685898 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 9,921E-03 0,06839327 ! forebrain regionalization GO:0021871 8 6 0,000 9,921E-03 0,06819786 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 9,921E-03 0,06800356 ! male meiosis GO:0007140 7 6 0,000 9,921E-03 0,06781037 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 9,921E-03 0,06761828 ! response to zinc ion GO:0010043 9 6 0,000 9,921E-03 0,06742726 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 9,921E-03 0,06723733 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 9,921E-03 0,06704846 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 9,921E-03 0,06686065 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 9,921E-03 0,06667389 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 9,921E-03 0,06648816 ! malate metabolic process GO:0006108 11 6 0,000 9,921E-03 0,06630348 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 9,921E-03 0,06611981 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 9,921E-03 0,06593716 ! protein refolding GO:0042026 15 6 0,000 9,921E-03 0,06575551 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 9,921E-03 0,06557487 ! opsonization GO:0008228 8 6 0,000 9,921E-03 0,06539521 ! mating behavior GO:0007617 7 6 0,000 9,921E-03 0,06521653 ! neuron remodeling GO:0016322 15 6 0,000 9,921E-03 0,06503883 ! erythrocyte maturation GO:0043249 7 6 0,000 9,921E-03 0,0648621 ! embryonic hemopoiesis GO:0035162 14 6 0,000 9,921E-03 0,06468632 ! equilibrioception GO:0050957 14 6 0,000 9,921E-03 0,06451149 ! protein amino acid dealkylation GO:0008214 12 6 0,000 9,921E-03 0,0643376 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 9,921E-03 0,06416465 ! photoreceptor cell development GO:0042461 10 6 0,000 9,921E-03 0,06399263 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 9,921E-03 0,06382153 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 9,921E-03 0,06365134 ! response to interferon-gamma GO:0034341 15 6 0,000 9,921E-03 0,06348205 ! toxin metabolic process GO:0009404 11 6 0,000 9,921E-03 0,06331366 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 9,921E-03 0,06314617 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,921E-03 0,06297955 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 9,921E-03 0,06281382 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 9,921E-03 0,06264895 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 9,921E-03 0,06248495 ! cGMP-mediated signaling GO:0019934 13 6 0,000 9,921E-03 0,0623218 ! activation of MAPKKK activity GO:0000185 12 6 0,000 9,921E-03 0,06215951 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 9,921E-03 0,06199805 ! thymic T cell selection GO:0045061 12 6 0,000 9,921E-03 0,06183744 ! protein lipoylation GO:0009249 10 6 0,000 9,921E-03 0,06167765 ! cysteine metabolic process GO:0006534 10 6 0,000 9,921E-03 0,06151869 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 9,921E-03 0,06136054 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,921E-03 0,06120321 ! glutamate catabolic process GO:0006538 10 6 0,000 9,921E-03 0,06104668 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 9,921E-03 0,06089095 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 9,921E-03 0,06073601 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 9,921E-03 0,06058186 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 9,921E-03 0,06042848 ! hyperosmotic response GO:0006972 9 6 0,000 9,921E-03 0,06027589 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 9,921E-03 0,06012406 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 9,921E-03 0,05997299 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 9,921E-03 0,05982268 ! urea metabolic process GO:0019627 7 6 0,000 9,921E-03 0,05967313 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 9,921E-03 0,05952432 ! neutrophil activation GO:0042119 8 6 0,000 9,921E-03 0,05937625 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 9,921E-03 0,05922891 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 9,921E-03 0,0590823 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 9,921E-03 0,05893642 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,921E-03 0,05879126 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 9,921E-03 0,05864681 ! neuron apoptosis GO:0051402 9 6 0,000 9,921E-03 0,05850307 ! nucleoside salvage GO:0043174 9 6 0,000 9,921E-03 0,05836003 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 9,921E-03 0,05821769 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 9,921E-03 0,05807604 ! T cell mediated immunity GO:0002456 16 6 0,000 9,921E-03 0,05793508 ! negative regulation of platelet activation GO:0010544 9 6 0,000 9,921E-03 0,0577948 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 9,921E-03 0,0576552 ! carnitine transport GO:0015879 10 6 0,000 9,921E-03 0,05751627 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 9,921E-03 0,05737801 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,921E-03 0,05724041 ! positive regulation of exocytosis GO:0045921 8 6 0,000 9,921E-03 0,05710347 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 9,921E-03 0,05696719 ! 5S class rRNA transcription GO:0042791 11 6 0,000 9,921E-03 0,05683155 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 9,921E-03 0,05669656 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 9,921E-03 0,05656221 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 9,921E-03 0,05642849 ! sodium ion homeostasis GO:0055078 11 6 0,000 9,921E-03 0,0562954 ! establishment of spindle localization GO:0051293 12 6 0,000 9,921E-03 0,05616294 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 9,921E-03 0,05603111 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 9,921E-03 0,05589989 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 9,921E-03 0,05576928 ! neural nucleus development GO:0048857 14 6 0,000 9,921E-03 0,05563928 ! response to UV-C GO:0010225 11 6 0,000 9,921E-03 0,05550989 ! astrocyte development GO:0014002 15 6 0,000 9,921E-03 0,05538109 ! protein targeting to lysosome GO:0006622 10 6 0,000 9,921E-03 0,0552529 ! purine base biosynthetic process GO:0009113 17 6 0,000 9,921E-03 0,05512529 ! interaction with symbiont GO:0051702 13 6 0,000 9,921E-03 0,05499827 ! regulation of dendrite development GO:0050773 16 6 0,000 9,921E-03 0,05487184 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,921E-03 0,05474599 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 9,921E-03 0,05462071 ! response to copper ion GO:0046688 10 6 0,000 9,921E-03 0,05449601 ! response to exogenous dsRNA GO:0043330 10 6 0,000 9,921E-03 0,05437187 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 9,921E-03 0,0542483 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,921E-03 0,05412529 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,921E-03 0,05400283 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 9,921E-03 0,05388093 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 9,921E-03 0,05375957 ! regulation of dopamine secretion GO:0014059 14 6 0,000 9,921E-03 0,05363877 ! nucleoside catabolic process GO:0009164 7 6 0,000 9,921E-03 0,0535185 ! hair follicle maturation GO:0048820 7 6 0,000 9,921E-03 0,05339877 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 9,921E-03 0,05327958 ! Schwann cell development GO:0014044 15 6 0,000 9,921E-03 0,05316092 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 9,921E-03 0,05304278 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,921E-03 0,05292517 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 9,921E-03 0,05280808 ! subpallium development GO:0021544 10 6 0,000 9,921E-03 0,0526915 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 9,921E-03 0,05257544 ! histone ubiquitination GO:0016574 8 6 0,000 9,921E-03 0,05245989 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 9,921E-03 0,05234485 ! maintenance of organ identity GO:0048496 9 6 0,000 9,921E-03 0,05223031 ! G2 phase GO:0051319 16 6 0,000 9,921E-03 0,05211627 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 9,921E-03 0,05200273 ! establishment of planar polarity GO:0001736 7 6 0,000 9,921E-03 0,05188968 ! regulation of mast cell activation GO:0033003 12 6 0,000 9,921E-03 0,05177712 ! membrane to membrane docking GO:0022614 14 6 0,000 9,921E-03 0,05166505 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 9,921E-03 0,05155346 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 9,921E-03 0,05144235 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 9,921E-03 0,05133172 ! receptor internalization GO:0031623 10 6 0,000 9,921E-03 0,05122157 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 9,921E-03 0,05111189 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 9,921E-03 0,05100267 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,921E-03 0,05089393 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 9,921E-03 0,05078564 ! protein deubiquitination GO:0016579 14 6 0,000 9,921E-03 0,05067782 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 9,921E-03 0,05057045 ! protein destabilization GO:0031648 9 6 0,000 9,921E-03 0,05046353 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 9,921E-03 0,05035707 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 9,921E-03 0,05025105 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,921E-03 0,05014549 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 9,921E-03 0,05004036 ! progesterone metabolic process GO:0042448 10 6 0,000 9,921E-03 0,04993567 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 9,921E-03 0,04983142 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 9,921E-03 0,04972761 ! negative regulation of axon extension GO:0030517 21 6 0,000 9,921E-03 0,04962422 ! removal of superoxide radicals GO:0019430 11 6 0,000 9,921E-03 0,04952127 ! triglyceride catabolic process GO:0019433 10 6 0,000 9,921E-03 0,04941874 ! determination of adult lifespan GO:0008340 15 6 0,000 9,921E-03 0,04931663 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 9,921E-03 0,04921495 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 9,921E-03 0,04911369 ! cerebellar cortex formation GO:0021697 8 6 0,000 9,921E-03 0,04901284 ! catecholamine transport GO:0051937 9 6 0,000 9,921E-03 0,0489124 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 9,921E-03 0,04881237 ! sensory cilium assembly GO:0035058 10 6 0,000 9,921E-03 0,04871276 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,921E-03 0,04861355 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 9,921E-03 0,04851474 ! maternal placenta development GO:0001893 12 6 0,000 9,921E-03 0,04841633 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 9,921E-03 0,04831832 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 9,921E-03 0,04822071 ! negative regulation of B cell activation GO:0050869 13 6 0,000 9,921E-03 0,04812349 ! protein amino acid prenylation GO:0018346 16 6 0,000 9,921E-03 0,04802666 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,921E-03 0,04793022 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 9,921E-03 0,04783417 ! positive regulation of coagulation GO:0050820 12 6 0,000 9,921E-03 0,0477385 ! bone development GO:0060348 189 91 1,000 0,01006735 0,04834741 ! nucleosome organization GO:0034728 138 92 1,000 0,01028024 0,04927145 ! forebrain development GO:0030900 188 95 1,000 0,01093086 0,05228559 ! tRNA transcription GO:0009304 14 7 0,000 0,01156477 0,055208 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01156477 0,05509868 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01156477 0,05498979 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01156477 0,05488133 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01156477 0,05477329 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01156477 0,05466568 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01156477 0,0545585 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01156477 0,05445173 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01156477 0,05434538 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01156477 0,05423944 ! prostate gland development GO:0030850 13 7 0,000 0,01156477 0,05413392 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01156477 0,0540288 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01156477 0,0539241 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01156477 0,05381979 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01156477 0,05371589 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01156477 0,0536124 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01156477 0,05350929 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01156477 0,05340659 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01156477 0,05330428 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01156477 0,05320236 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01156477 0,05310083 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01156477 0,05299968 ! glycolipid transport GO:0046836 10 7 0,000 0,01156477 0,05289892 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01156477 0,05279855 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01156477 0,05269855 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01156477 0,05259893 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01156477 0,05249969 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01156477 0,05240082 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01156477 0,05230232 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01156477 0,05220419 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01156477 0,05210643 ! mRNA stabilization GO:0048255 18 7 0,000 0,01156477 0,05200903 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01156477 0,051912 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01156477 0,05181533 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01156477 0,05171902 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01156477 0,05162307 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01156477 0,05152747 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01156477 0,05143222 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01156477 0,05133733 ! lipoprotein transport GO:0042953 14 7 0,000 0,01156477 0,05124279 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01156477 0,05114859 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01156477 0,05105474 ! rhythmic behavior GO:0007622 15 7 0,000 0,01156477 0,05096123 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01156477 0,05086807 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01156477 0,05077524 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01156477 0,05068276 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01156477 0,05059061 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01156477 0,05049879 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01156477 0,05040731 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01156477 0,05031615 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01156477 0,05022533 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01156477 0,05013483 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01156477 0,05004466 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01156477 0,04995482 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01156477 0,04986529 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01156477 0,04977609 ! spinal cord patterning GO:0021511 13 7 0,000 0,01156477 0,0496872 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01156477 0,04959863 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01156477 0,04951038 ! adrenal gland development GO:0030325 17 7 0,000 0,01156477 0,04942244 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01156477 0,04933481 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01156477 0,04924749 ! ovulation GO:0030728 9 7 0,000 0,01156477 0,04916048 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01156477 0,04907378 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01156477 0,04898738 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01156477 0,04890129 ! microtubule nucleation GO:0007020 20 7 0,000 0,01156477 0,0488155 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01156477 0,04873001 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01156477 0,04864481 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01156477 0,04855992 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01156477 0,04847532 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01156477 0,04839101 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01156477 0,048307 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01156477 0,04822328 ! galactose metabolic process GO:0006012 13 7 0,000 0,01156477 0,04813985 ! vesicle fusion GO:0006906 17 7 0,000 0,01156477 0,04805671 ! response to dietary excess GO:0002021 8 7 0,000 0,01156477 0,04797385 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01156477 0,04789128 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01156477 0,04780899 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01156477 0,04772699 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01156477 0,04764526 ! organ growth GO:0035265 15 7 0,000 0,01156477 0,04756382 ! purine salvage GO:0043101 10 7 0,000 0,01156477 0,04748265 ! nucleoside transport GO:0015858 8 7 0,000 0,01156477 0,04740176 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01156477 0,04732115 ! parturition GO:0007567 14 7 0,000 0,01156477 0,0472408 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01156477 0,04716073 ! rRNA modification GO:0000154 14 7 0,000 0,01156477 0,04708094 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01156477 0,04700141 ! spindle checkpoint GO:0031577 15 7 0,000 0,01156477 0,04692215 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01156477 0,04684315 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01156477 0,04676443 ! macrophage differentiation GO:0030225 11 7 0,000 0,01156477 0,04668596 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01156477 0,04660776 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01156477 0,04652982 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01156477 0,04645214 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01156477 0,04637472 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01156477 0,04629756 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01156477 0,04622065 ! fibrinolysis GO:0042730 10 7 0,000 0,01156477 0,046144 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01156477 0,0460676 ! eating behavior GO:0042755 7 7 0,000 0,01156477 0,04599146 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01156477 0,04591557 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01156477 0,04583992 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01156477 0,04576453 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01156477 0,04568938 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01156477 0,04561448 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01156477 0,04553983 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01156477 0,04546541 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01156477 0,04539125 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01156477 0,04531732 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01156477 0,04524363 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01156477 0,04517018 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01156477 0,04509697 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01156477 0,045024 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01156477 0,04495127 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01156477 0,04487876 ! regulation of meiosis GO:0040020 12 7 0,000 0,01156477 0,04480649 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01156477 0,04473446 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01156477 0,04466265 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01156477 0,04459108 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01156477 0,04451973 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01156477 0,04444862 ! transcription termination GO:0006353 13 7 0,000 0,01156477 0,04437772 ! response to tumor cell GO:0002347 13 7 0,000 0,01156477 0,04430706 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01156477 0,04423662 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01156477 0,0441664 ! anaphase GO:0051322 17 7 0,000 0,01156477 0,04409641 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01156477 0,04402664 ! axonal fasciculation GO:0007413 18 7 0,000 0,01156477 0,04395708 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01156477 0,04388775 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01156477 0,04381864 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01156477 0,04374974 ! diuresis GO:0030146 12 7 0,000 0,01156477 0,04368106 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01156477 0,04361259 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01156477 0,04354434 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01156477 0,0434763 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01156477 0,04340848 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01156477 0,04334086 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01156477 0,04327346 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01156477 0,04320626 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01156477 0,04313928 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01156477 0,0430725 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01156477 0,04300592 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01156477 0,04293956 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01156477 0,04287339 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01156477 0,04280744 ! lymph node development GO:0048535 10 7 0,000 0,01156477 0,04274168 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01156477 0,04267612 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01156477 0,04261077 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01156477 0,04254562 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01156477 0,04248066 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01156477 0,0424159 ! adult feeding behavior GO:0008343 9 7 0,000 0,01156477 0,04235134 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01156477 0,04228698 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01156477 0,04222281 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01156477 0,04215884 ! muscle adaptation GO:0043500 14 7 0,000 0,01156477 0,04209506 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01156477 0,04203147 ! retina homeostasis GO:0001895 12 7 0,000 0,01156477 0,04196807 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01156477 0,04190487 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01156477 0,04184185 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01156477 0,04177903 ! protein prenylation GO:0018342 18 7 0,000 0,01156477 0,04171639 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01156477 0,04165394 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01156477 0,04159168 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01156477 0,0415296 ! cell cycle arrest GO:0007050 213 100 1,000 0,01205462 0,04322418 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01320614 0,04728271 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01320614 0,04721245 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01320614 0,0471424 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01320614 0,04707256 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01320614 0,04700293 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01320614 0,0469335 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01320614 0,04686427 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01320614 0,04679526 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01320614 0,04672644 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01320614 0,04665782 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01320614 0,04658941 ! meiotic prophase I GO:0007128 13 8 0,000 0,01320614 0,0465212 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01320614 0,04645318 ! oligopeptide transport GO:0006857 15 8 0,000 0,01320614 0,04638537 ! UTP metabolic process GO:0046051 8 8 0,000 0,01320614 0,04631775 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01320614 0,04625033 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01320614 0,04618311 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01320614 0,04611608 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01320614 0,04604924 ! succinate metabolic process GO:0006105 14 8 0,000 0,01320614 0,0459826 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01320614 0,04591615 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01320614 0,0458499 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01320614 0,04578383 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01320614 0,04571795 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01320614 0,04565227 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01320614 0,04558677 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01320614 0,04552146 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01320614 0,04545634 ! reflex GO:0060004 16 8 0,000 0,01320614 0,0453914 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01320614 0,04532665 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01320614 0,04526208 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01320614 0,04519769 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01320614 0,04513349 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01320614 0,04506947 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01320614 0,04500564 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01320614 0,04494198 ! pigment granule organization GO:0048753 16 8 0,000 0,01320614 0,0448785 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01320614 0,0448152 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01320614 0,04475208 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01320614 0,04468914 ! histidine metabolic process GO:0006547 16 8 0,000 0,01320614 0,04462637 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01320614 0,04456378 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01320614 0,04450137 ! glycine catabolic process GO:0006546 13 8 0,000 0,01320614 0,04443913 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01320614 0,04437706 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01320614 0,04431517 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01320614 0,04425345 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01320614 0,0441919 ! melanin metabolic process GO:0006582 15 8 0,000 0,01320614 0,04413053 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01320614 0,04406932 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01320614 0,04400828 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01320614 0,04394741 ! macrophage activation GO:0042116 12 8 0,000 0,01320614 0,04388671 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01320614 0,04382618 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01320614 0,04376581 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01320614 0,04370561 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01320614 0,04364557 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01320614 0,0435857 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01320614 0,043526 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01320614 0,04346645 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01320614 0,04340707 ! osteoblast development GO:0002076 16 8 0,000 0,01320614 0,04334786 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01320614 0,0432888 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01320614 0,0432299 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01320614 0,04317117 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01320614 0,04311259 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01320614 0,04305417 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01320614 0,04299591 ! response to UV-B GO:0010224 16 8 0,000 0,01320614 0,04293781 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01320614 0,04287986 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01320614 0,04282207 ! intermediate filament organization GO:0045109 12 8 0,000 0,01320614 0,04276444 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01320614 0,04270696 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01320614 0,04264964 ! cellular extravasation GO:0045123 12 8 0,000 0,01320614 0,04259246 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01320614 0,04253545 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01320614 0,04247858 ! response to antibiotic GO:0046677 11 8 0,000 0,01320614 0,04242187 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01320614 0,0423653 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01320614 0,04230889 ! DNA topological change GO:0006265 12 8 0,000 0,01320614 0,04225263 ! response to tropane GO:0014073 15 8 0,000 0,01320614 0,04219652 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01320614 0,04214055 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01320614 0,04208474 ! melanosome transport GO:0032402 13 8 0,000 0,01320614 0,04202907 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,01320614 0,04197355 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01320614 0,04191818 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01320614 0,04186295 ! mast cell activation GO:0045576 14 8 0,000 0,01320614 0,04180787 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01320614 0,04175293 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01320614 0,04169813 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01320614 0,04164348 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01320614 0,04158898 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01320614 0,04153461 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01320614 0,04148039 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01320614 0,04142631 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01320614 0,04137237 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01320614 0,04131857 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01320614 0,04126491 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01320614 0,04121139 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01320614 0,041158 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01320614 0,04110476 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01320614 0,04105165 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01320614 0,04099868 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01320614 0,04094585 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01320614 0,04089315 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01320614 0,04084059 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01320614 0,04078816 ! hormone catabolic process GO:0042447 17 8 0,000 0,01320614 0,04073587 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01320614 0,04068371 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01320614 0,04063169 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01320614 0,04057979 ! ATP catabolic process GO:0006200 11 8 0,000 0,01320614 0,04052803 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01320614 0,04047641 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01320614 0,04042491 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01320614 0,04037354 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01320614 0,04032231 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01320614 0,0402712 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01320614 0,04022023 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01320614 0,04016938 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01320614 0,04011866 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01320614 0,04006807 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01320614 0,04001761 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01320614 0,03996727 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01320614 0,03991706 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01320614 0,03986697 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01320614 0,03981702 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01320614 0,03976718 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01320614 0,03971747 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01320614 0,03966789 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01484484 0,04453453 ! axon extension GO:0048675 15 9 0,000 0,01484484 0,04447907 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01484484 0,04442375 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01484484 0,04436857 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01484484 0,04431352 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01484484 0,04425861 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01484484 0,04420383 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01484484 0,04414919 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01484484 0,04409469 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01484484 0,04404032 ! phosphate transport GO:0006817 19 9 0,000 0,01484484 0,04398608 ! reproductive behavior GO:0019098 19 9 0,000 0,01484484 0,04393198 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01484484 0,04387801 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01484484 0,04382417 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01484484 0,04377046 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01484484 0,04371689 ! GTP metabolic process GO:0046039 9 9 0,000 0,01484484 0,04366344 ! RNA methylation GO:0001510 15 9 0,000 0,01484484 0,04361013 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01484484 0,04355695 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01484484 0,04350389 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01484484 0,04345097 ! artery development GO:0060840 24 9 0,000 0,01484484 0,04339817 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01484484 0,04334551 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01484484 0,04329297 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01484484 0,04324055 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01484484 0,04318827 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01484484 0,04313611 ! chemosensory behavior GO:0007635 20 9 0,000 0,01484484 0,04308407 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01484484 0,04303216 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01484484 0,04298038 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01484484 0,04292872 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01484484 0,04287719 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01484484 0,04282578 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01484484 0,04277449 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01484484 0,04272332 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01484484 0,04267228 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01484484 0,04262136 ! protein targeting to ER GO:0045047 22 9 0,000 0,01484484 0,04257056 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01484484 0,04251988 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01484484 0,04246932 ! T cell selection GO:0045058 23 9 0,000 0,01484484 0,04241888 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01484484 0,04236856 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01484484 0,04231836 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01484484 0,04226828 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01484484 0,04221832 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01484484 0,04216847 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01484484 0,04211875 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01484484 0,04206914 ! mannose metabolic process GO:0006013 13 9 0,000 0,01484484 0,04201964 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01484484 0,04197027 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01484484 0,04192101 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01484484 0,04187186 ! receptor clustering GO:0043113 18 9 0,000 0,01484484 0,04182283 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01484484 0,04177391 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01484484 0,04172511 ! ruffle organization GO:0031529 15 9 0,000 0,01484484 0,04167643 ! retinol metabolic process GO:0042572 18 9 0,000 0,01484484 0,04162785 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01484484 0,04157939 ! behavioral fear response GO:0001662 22 9 0,000 0,01484484 0,04153104 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01484484 0,04148281 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01484484 0,04143468 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01484484 0,04138667 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01484484 0,04133877 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01484484 0,04129098 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01484484 0,0412433 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01484484 0,04119573 ! segment specification GO:0007379 13 9 0,000 0,01484484 0,04114827 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01484484 0,04110092 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01484484 0,04105367 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01484484 0,04100654 ! response to amine stimulus GO:0014075 13 9 0,000 0,01484484 0,04095951 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01484484 0,0409126 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01484484 0,04086579 ! erythrocyte development GO:0048821 15 9 0,000 0,01484484 0,04081908 ! gas homeostasis GO:0033483 16 9 0,000 0,01484484 0,04077248 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01484484 0,04072599 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01484484 0,04067961 ! renal water homeostasis GO:0003091 14 9 0,000 0,01484484 0,04063333 ! postreplication repair GO:0006301 22 9 0,000 0,01484484 0,04058716 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01484484 0,04054109 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01484484 0,04049512 ! icosanoid secretion GO:0032309 15 9 0,000 0,01484484 0,04044926 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01484484 0,0404035 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01484484 0,04035785 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01484484 0,0403123 ! regulation of cell division GO:0051302 15 9 0,000 0,01484484 0,04026685 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01484484 0,04022151 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01484484 0,04017626 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01484484 0,04013112 ! sterol catabolic process GO:0016127 11 9 0,000 0,01484484 0,04008608 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01484484 0,04004114 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01484484 0,0399963 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01484484 0,03995156 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01484484 0,03990692 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01484484 0,03986238 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01484484 0,03981794 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01484484 0,0397736 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01484484 0,03972936 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01484484 0,03968522 ! purine base metabolic process GO:0006144 21 9 0,000 0,01484484 0,03964117 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01484484 0,03959722 ! pigment granule transport GO:0051904 17 9 0,000 0,01484484 0,03955337 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01484484 0,03950962 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01484484 0,03946596 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01484484 0,0394224 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01484484 0,03937894 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01484484 0,03933557 ! mitochondrion localization GO:0051646 15 9 0,000 0,01484484 0,0392923 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01648088 0,04357472 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01648088 0,04352689 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01648088 0,04347916 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01648088 0,04343154 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01648088 0,04338402 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01648088 0,04333661 ! synapsis GO:0007129 13 10 0,000 0,01648088 0,0432893 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01648088 0,04324209 ! N-glycan processing GO:0006491 20 10 0,000 0,01648088 0,04319499 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01648088 0,04314798 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01648088 0,04310108 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01648088 0,04305429 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01648088 0,04300759 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01648088 0,04296099 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01648088 0,0429145 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01648088 0,04286811 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01648088 0,04282181 ! androgen metabolic process GO:0008209 17 10 0,000 0,01648088 0,04277562 ! phospholipid efflux GO:0033700 16 10 0,000 0,01648088 0,04272952 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01648088 0,04268353 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01648088 0,04263763 ! lung alveolus development GO:0048286 26 10 0,000 0,01648088 0,04259183 ! pathogenesis GO:0009405 13 10 0,000 0,01648088 0,04254614 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01648088 0,04250053 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01648088 0,04245503 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01648088 0,04240962 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01648088 0,04236431 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01648088 0,0423191 ! endoderm development GO:0007492 16 10 0,000 0,01648088 0,04227399 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01648088 0,04222896 ! arginine catabolic process GO:0006527 13 10 0,000 0,01648088 0,04218404 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01648088 0,04213921 ! proline metabolic process GO:0006560 13 10 0,000 0,01648088 0,04209448 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01648088 0,04204984 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01648088 0,04200529 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01648088 0,04196084 ! V(D)J recombination GO:0033151 28 10 0,000 0,01648088 0,04191649 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01648088 0,04187223 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01648088 0,04182806 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01648088 0,04178398 ! B cell proliferation GO:0042100 18 10 0,000 0,01648088 0,04174 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01648088 0,04169611 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01648088 0,04165231 ! multicellular organism growth GO:0035264 18 10 0,000 0,01648088 0,0416086 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01648088 0,04156499 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01648088 0,04152146 ! epithelial cell development GO:0002064 20 10 0,000 0,01648088 0,04147803 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01648088 0,04143469 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01648088 0,04139144 ! macroautophagy GO:0016236 17 10 0,000 0,01648088 0,04134828 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01648088 0,04130521 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01648088 0,04126222 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01648088 0,04121933 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01648088 0,04117653 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01648088 0,04113382 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01648088 0,04109119 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01648088 0,04104865 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01648088 0,0410062 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01648088 0,04096384 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01648088 0,04092157 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01648088 0,04087938 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01648088 0,04083728 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01648088 0,04079527 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01648088 0,04075334 ! response to dsRNA GO:0043331 20 10 0,000 0,01648088 0,0407115 ! DNA ligation GO:0006266 19 10 0,000 0,01648088 0,04066974 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01648088 0,04062807 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01648088 0,04058649 ! melanosome localization GO:0032400 16 10 0,000 0,01648088 0,04054499 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01648088 0,04050357 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01648088 0,04046224 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01648088 0,040421 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01648088 0,04037984 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01648088 0,04033876 ! mRNA cleavage GO:0006379 17 10 0,000 0,01648088 0,04029776 ! protein sumoylation GO:0016925 15 10 0,000 0,01648088 0,04025685 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01648088 0,04021602 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01648088 0,04017528 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01648088 0,04013461 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01648088 0,04009403 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01648088 0,04005353 ! salivary gland development GO:0007431 27 10 0,000 0,01648088 0,04001312 ! prophase GO:0051324 15 10 0,000 0,01648088 0,03997278 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01648088 0,03993253 ! apical protein localization GO:0045176 15 10 0,000 0,01648088 0,03989235 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01648088 0,03985226 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01648088 0,03981225 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01648088 0,03977232 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01648088 0,03973246 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01648088 0,03969269 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01648088 0,039653 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01648088 0,03961338 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01648088 0,03957385 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01648088 0,03953439 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01648088 0,03949502 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01648088 0,03945572 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01648088 0,0394165 ! oocyte development GO:0048599 17 10 0,000 0,01648088 0,03937736 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01648088 0,03933829 ! blastocyst formation GO:0001825 17 10 0,000 0,01648088 0,0392993 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01648088 0,03926039 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01648088 0,03922156 ! activation of innate immune response GO:0002218 12 10 0,000 0,01648088 0,0391828 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01648088 0,03914412 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01648088 0,03910552 ! response to nicotine GO:0035094 20 10 0,000 0,01648088 0,03906699 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01648088 0,03902854 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01648088 0,03899017 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01648088 0,03895186 ! localization within membrane GO:0051668 20 10 0,000 0,01648088 0,03891364 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01811425 0,04272833 ! respiratory burst GO:0045730 17 11 0,000 0,01811425 0,04268648 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01811425 0,04264471 ! neuron fate specification GO:0048665 17 11 0,000 0,01811425 0,04260302 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01811425 0,04256142 ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01811425 0,0425199 ! thyroid gland development GO:0030878 26 11 0,000 0,01811425 0,04247845 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01811425 0,04243709 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01811425 0,04239581 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01811425 0,04235461 ! response to pain GO:0048265 24 11 0,000 0,01811425 0,04231349 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01811425 0,04227245 ! T cell proliferation GO:0042098 26 11 0,000 0,01811425 0,04223149 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01811425 0,0421906 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01811425 0,0421498 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01811425 0,04210908 ! bone resorption GO:0045453 16 11 0,000 0,01811425 0,04206843 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01811425 0,04202786 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01811425 0,04198737 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01811425 0,04194696 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01811425 0,04190663 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01811425 0,04186637 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01811425 0,04182619 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01811425 0,04178609 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01811425 0,04174607 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01811425 0,04170612 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01811425 0,04166625 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01811425 0,04162645 ! lipid digestion GO:0044241 18 11 0,000 0,01811425 0,04158673 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01811425 0,04154709 ! UV protection GO:0009650 19 11 0,000 0,01811425 0,04150752 ! adult heart development GO:0007512 14 11 0,000 0,01811425 0,04146802 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01811425 0,04142861 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01811425 0,04138926 ! temperature homeostasis GO:0001659 17 11 0,000 0,01811425 0,04134999 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01811425 0,0413108 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01811425 0,04127168 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01811425 0,04123263 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01811425 0,04119366 ! regulation of organ growth GO:0046620 13 11 0,000 0,01811425 0,04115476 ! pigment granule localization GO:0051875 20 11 0,000 0,01811425 0,04111594 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01811425 0,04107718 ! vasoconstriction GO:0042310 18 11 0,000 0,01811425 0,04103851 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01811425 0,0409999 ! embryonic axis specification GO:0000578 18 11 0,000 0,01811425 0,04096137 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01811425 0,0409229 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01811425 0,04088452 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01811425 0,0408462 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01811425 0,04080795 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01811425 0,04076978 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01811425 0,04073168 ! zymogen activation GO:0031638 15 11 0,000 0,01811425 0,04069364 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01811425 0,04065568 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01811425 0,04061779 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01811425 0,04057997 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01811425 0,04054223 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01811425 0,04050455 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01811425 0,04046694 ! acid secretion GO:0046717 18 11 0,000 0,01811425 0,0404294 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01811425 0,04039193 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01811425 0,04035453 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01811425 0,0403172 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01811425 0,04027994 ! oocyte differentiation GO:0009994 18 11 0,000 0,01811425 0,04024275 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01811425 0,04020562 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01811425 0,04016857 ! cholesterol efflux GO:0033344 19 11 0,000 0,01811425 0,04013158 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01811425 0,04009466 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01811425 0,04005781 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01811425 0,04002102 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01811425 0,03998431 ! embryonic gut development GO:0048566 15 11 0,000 0,01811425 0,03994766 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01811425 0,03991107 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01811425 0,03987456 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01811425 0,03983811 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01811425 0,03980173 ! defense response to fungus GO:0050832 13 11 0,000 0,01811425 0,03976541 ! developmental induction GO:0031128 19 11 0,000 0,01811425 0,03972916 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01811425 0,03969298 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01811425 0,03965686 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01811425 0,03962081 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01811425 0,03958483 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01811425 0,0395489 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01811425 0,03951305 ! nucleus localization GO:0051647 19 11 0,000 0,01811425 0,03947726 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01811425 0,03944153 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01974497 0,04295334 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01974497 0,04291454 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01974497 0,0428758 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01974497 0,04283714 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01974497 0,04279855 ! virus-host interaction GO:0019048 29 12 0,000 0,01974497 0,04276003 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,01974497 0,04272158 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01974497 0,04268319 ! cartilage condensation GO:0001502 20 12 0,000 0,01974497 0,04264488 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01974497 0,04260663 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01974497 0,04256845 ! protein complex disassembly GO:0043241 27 12 0,000 0,01974497 0,04253034 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01974497 0,0424923 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01974497 0,04245433 ! hippocampus development GO:0021766 26 12 0,000 0,01974497 0,04241642 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01974497 0,04237858 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01974497 0,04234081 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01974497 0,04230311 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01974497 0,04226547 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01974497 0,0422279 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01974497 0,0421904 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01974497 0,04215297 ! drug transport GO:0015893 16 12 0,000 0,01974497 0,0421156 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01974497 0,04207829 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01974497 0,04204105 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01974497 0,04200388 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01974497 0,04196678 ! focal adhesion formation GO:0048041 35 12 0,000 0,01974497 0,04192974 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01974497 0,04189276 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01974497 0,04185585 ! forebrain cell migration GO:0021885 21 12 0,000 0,01974497 0,04181901 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01974497 0,04178223 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01974497 0,04174551 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01974497 0,04170886 ! entry into host cell GO:0030260 32 12 0,000 0,01974497 0,04167227 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01974497 0,04163575 ! monoamine transport GO:0015844 18 12 0,000 0,01974497 0,04159929 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01974497 0,0415629 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01974497 0,04152657 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01974497 0,0414903 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01974497 0,04145409 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01974497 0,04141795 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01974497 0,04138187 ! protein homotetramerization GO:0051289 21 12 0,000 0,01974497 0,04134586 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01974497 0,04130991 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01974497 0,04127402 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01974497 0,04123819 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01974497 0,04120242 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01974497 0,04116672 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01974497 0,04113108 ! cranial nerve development GO:0021545 20 12 0,000 0,01974497 0,04109549 ! fucose catabolic process GO:0019317 22 12 0,000 0,01974497 0,04105998 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01974497 0,04102452 ! histone acetylation GO:0016573 26 12 0,000 0,01974497 0,04098912 ! histone methylation GO:0016571 26 12 0,000 0,01974497 0,04095379 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01974497 0,04091851 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01974497 0,0408833 ! gland morphogenesis GO:0022612 29 12 0,000 0,01974497 0,04084814 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01974497 0,04081305 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01974497 0,04077802 ! T cell homeostasis GO:0043029 25 12 0,000 0,01974497 0,04074305 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01974497 0,04070813 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01974497 0,04067328 ! spleen development GO:0048536 22 12 0,000 0,01974497 0,04063849 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01974497 0,04060375 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01974497 0,04056908 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01974497 0,04053446 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01974497 0,04049991 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01974497 0,04046541 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01974497 0,04043097 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01974497 0,04039659 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01974497 0,04036227 ! response to cold GO:0009409 17 12 0,000 0,01974497 0,04032801 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01974497 0,0402938 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01974497 0,04025965 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02137303 0,04354234 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02137303 0,0435055 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02137303 0,04346873 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02137303 0,04343201 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02137303 0,04339536 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02137303 0,04335877 ! lipid localization GO:0010876 28 13 0,000 0,02137303 0,04332224 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02137303 0,04328578 ! organelle fusion GO:0048284 32 13 0,000 0,02137303 0,04324937 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02137303 0,04321303 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02137303 0,04317675 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02137303 0,04314052 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02137303 0,04310436 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02137303 0,04306826 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02137303 0,04303222 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02137303 0,04299624 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02137303 0,04296032 ! methionine metabolic process GO:0006555 27 13 0,000 0,02137303 0,04292446 ! plasma membrane organization GO:0007009 24 13 0,000 0,02137303 0,04288866 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02137303 0,04285292 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02137303 0,04281724 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02137303 0,04278162 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02137303 0,04274606 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02137303 0,04271055 ! response to X-ray GO:0010165 25 13 0,000 0,02137303 0,04267511 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02137303 0,04263972 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02137303 0,04260439 ! exocrine system development GO:0035272 32 13 0,000 0,02137303 0,04256913 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02137303 0,04253392 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02137303 0,04249876 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02137303 0,04246367 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02137303 0,04242863 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02137303 0,04239366 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02137303 0,04235874 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02137303 0,04232387 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02137303 0,04228907 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02137303 0,04225432 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02137303 0,04221963 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02137303 0,04218499 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02137303 0,04215041 ! ribosome assembly GO:0042255 17 13 0,000 0,02137303 0,04211589 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,02137303 0,04208143 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02137303 0,04204702 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02137303 0,04201267 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02137303 0,04197837 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02137303 0,04194413 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02137303 0,04190995 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02137303 0,04187582 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02137303 0,04184175 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02137303 0,04180773 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02137303 0,04177376 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02137303 0,04173986 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02137303 0,04170601 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02137303 0,04167221 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02137303 0,04163847 ! embryonic placenta development GO:0001892 23 13 0,000 0,02137303 0,04160478 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02137303 0,04157114 ! insulin secretion GO:0030073 23 13 0,000 0,02137303 0,04153756 ! actin filament polymerization GO:0030041 24 13 0,000 0,02137303 0,04150404 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02137303 0,04147057 ! acrosome reaction GO:0007340 18 13 0,000 0,02137303 0,04143715 ! rRNA transcription GO:0009303 25 14 0,000 0,02299844 0,04455253 ! lactation GO:0007595 26 14 0,000 0,02299844 0,04451669 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02299844 0,0444809 ! reproductive cellular process GO:0048610 20 14 0,000 0,02299844 0,04444517 ! tRNA modification GO:0006400 20 14 0,000 0,02299844 0,0444095 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02299844 0,04437389 ! regulation of S phase GO:0033261 23 14 0,000 0,02299844 0,04433833 ! water transport GO:0006833 21 14 0,000 0,02299844 0,04430284 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02299844 0,04426739 ! non-recombinational repair GO:0000726 25 14 0,000 0,02299844 0,04423201 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02299844 0,04419668 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02299844 0,04416141 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02299844 0,04412619 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02299844 0,04409103 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02299844 0,04405592 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02299844 0,04402088 ! palate development GO:0060021 31 14 0,000 0,02299844 0,04398588 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02299844 0,04395095 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02299844 0,04391606 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02299844 0,04388124 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02299844 0,04384647 ! arginine metabolic process GO:0006525 17 14 0,000 0,02299844 0,04381175 ! regulation of heart rate GO:0002027 24 14 0,000 0,02299844 0,04377709 ! organic alcohol transport GO:0015850 29 14 0,000 0,02299844 0,04374248 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02299844 0,04370793 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02299844 0,04367343 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02299844 0,04363899 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02299844 0,0436046 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02299844 0,04357027 ! L-amino acid transport GO:0015807 30 14 0,000 0,02299844 0,04353599 ! bone mineralization GO:0030282 17 14 0,000 0,02299844 0,04350176 ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02299844 0,04346759 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02299844 0,04343347 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02299844 0,04339941 ! cerebellum development GO:0021549 21 14 0,000 0,02299844 0,04336539 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02299844 0,04333143 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02299844 0,04329753 ! response to gamma radiation GO:0010332 28 14 0,000 0,02299844 0,04326368 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02299844 0,04322988 ! cofactor transport GO:0051181 26 14 0,000 0,02299844 0,04319613 ! NADP metabolic process GO:0006739 24 14 0,000 0,02299844 0,04316243 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02299844 0,04312879 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02299844 0,0430952 ! intestinal absorption GO:0050892 25 14 0,000 0,02299844 0,04306167 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02299844 0,04302818 ! oxygen transport GO:0015671 21 14 0,000 0,02299844 0,04299475 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02299844 0,04296137 ! male genitalia development GO:0030539 24 14 0,000 0,02299844 0,04292804 ! regulation of RNA stability GO:0043487 32 14 0,000 0,02299844 0,04289476 ! regulation of axon extension GO:0030516 37 14 0,000 0,02299844 0,04286153 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,02299844 0,04282836 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02299844 0,04279524 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0246212 0,04577945 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0246212 0,0457441 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0246212 0,04570881 ! superoxide anion generation GO:0042554 20 15 0,000 0,0246212 0,04567356 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0246212 0,04563838 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0246212 0,04560324 ! copper ion transport GO:0006825 20 15 0,000 0,0246212 0,04556816 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0246212 0,04553314 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0246212 0,04549817 ! sulfate transport GO:0008272 23 15 0,000 0,0246212 0,04546325 ! response to cAMP GO:0051591 22 15 0,000 0,0246212 0,04542838 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0246212 0,04539357 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0246212 0,04535882 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0246212 0,04532411 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0246212 0,04528946 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0246212 0,04525486 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0246212 0,04522032 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0246212 0,04518582 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0246212 0,04515138 ! pituitary gland development GO:0021983 29 15 0,000 0,0246212 0,04511699 ! vesicle coating GO:0006901 33 15 0,000 0,0246212 0,04508266 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0246212 0,04504837 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0246212 0,04501414 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0246212 0,04497996 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0246212 0,04494584 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0246212 0,04491176 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0246212 0,04487774 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0246212 0,04484376 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0246212 0,04480984 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0246212 0,04477597 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0246212 0,04474215 ! histone deacetylation GO:0016575 20 15 0,000 0,0246212 0,04470839 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0246212 0,04467467 ! tissue regeneration GO:0042246 26 15 0,000 0,0246212 0,044641 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0246212 0,04460739 ! water homeostasis GO:0030104 27 15 0,000 0,0246212 0,04457382 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0246212 0,04454031 ! muscle maintenance GO:0046716 26 15 0,000 0,0246212 0,04450685 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0246212 0,04447343 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0246212 0,04444007 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0246212 0,04440676 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0246212 0,04437349 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0246212 0,04434028 ! cell killing GO:0001906 29 15 0,000 0,0246212 0,04430712 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0246212 0,044274 ! detection of bacterium GO:0016045 18 15 0,000 0,0246212 0,04424094 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0246212 0,04420792 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0246212 0,04417495 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0246212 0,04414204 ! peptide hormone processing GO:0016486 23 15 0,000 0,0246212 0,04410917 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02624133 0,04697666 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02624133 0,04694173 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02624133 0,04690686 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02624133 0,04687203 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02624133 0,04683726 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02624133 0,04680254 ! bone remodeling GO:0046849 27 16 0,000 0,02624133 0,04676787 ! filopodium assembly GO:0046847 32 16 0,000 0,02624133 0,04673326 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02624133 0,04669869 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02624133 0,04666417 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02624133 0,04662971 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02624133 0,0465953 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02624133 0,04656094 ! startle response GO:0001964 28 16 0,000 0,02624133 0,04652662 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02624133 0,04649236 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02624133 0,04645815 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02624133 0,04642399 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02624133 0,04638988 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02624133 0,04635582 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02624133 0,04632181 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02624133 0,04628785 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02624133 0,04625394 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02624133 0,04622008 ! response to osmotic stress GO:0006970 25 16 0,000 0,02624133 0,04618627 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02624133 0,04615251 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02624133 0,04611879 ! fructose metabolic process GO:0006000 25 16 0,000 0,02624133 0,04608513 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02624133 0,04605152 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02624133 0,04601795 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02624133 0,04598443 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02624133 0,04595097 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02624133 0,04591755 ! axon cargo transport GO:0008088 43 16 0,000 0,02624133 0,04588418 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02624133 0,04585086 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02624133 0,04581758 ! DNA replication initiation GO:0006270 27 16 0,000 0,02624133 0,04578436 ! neuron recognition GO:0008038 35 16 0,000 0,02624133 0,04575118 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02624133 0,04571805 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02624133 0,04568497 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02624133 0,04565194 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02624133 0,04561895 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02624133 0,04558601 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02624133 0,04555312 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02624133 0,04552028 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02624133 0,04548748 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02624133 0,04545474 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02624133 0,04542203 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02624133 0,04538938 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02624133 0,04535677 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02624133 0,04532421 ! defense response to virus GO:0051607 37 16 0,000 0,02624133 0,0452917 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02785881 0,04804896 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02785881 0,04801454 ! metencephalon development GO:0022037 30 17 0,000 0,02785881 0,04798017 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02785881 0,04794585 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02785881 0,04791158 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02785881 0,04787736 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02785881 0,04784318 ! signal complex assembly GO:0007172 41 17 0,000 0,02785881 0,04780906 ! endothelial cell migration GO:0043542 28 17 0,000 0,02785881 0,04777498 ! inositol metabolic process GO:0006020 28 17 0,000 0,02785881 0,04774095 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02785881 0,04770697 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02785881 0,04767304 ! glial cell development GO:0021782 27 17 0,000 0,02785881 0,04763916 ! limbic system development GO:0021761 36 17 0,000 0,02785881 0,04760533 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02785881 0,04757154 ! adult walking behavior GO:0007628 33 17 0,000 0,02785881 0,0475378 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02785881 0,04750411 ! heart looping GO:0001947 30 17 0,000 0,02785881 0,04747047 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02785881 0,04743687 ! myoblast differentiation GO:0045445 45 17 0,000 0,02785881 0,04740332 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02785881 0,04736982 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02785881 0,04733637 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02785881 0,04730296 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02785881 0,0472696 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02785881 0,04723629 ! glycine metabolic process GO:0006544 28 17 0,000 0,02785881 0,04720303 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,02785881 0,04716981 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02785881 0,04713664 ! NAD metabolic process GO:0019674 29 17 0,000 0,02785881 0,04710351 ! membrane budding GO:0006900 37 17 0,000 0,02785881 0,04707043 ! DNA integration GO:0015074 29 17 0,000 0,02785881 0,0470374 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02785881 0,04700442 ! regulation of protein binding GO:0043393 33 17 0,000 0,02785881 0,04697148 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02785881 0,04693858 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02785881 0,04690574 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02785881 0,04687294 ! genitalia development GO:0048806 30 17 0,000 0,02785881 0,04684018 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02785881 0,04680747 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02785881 0,04677481 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02785881 0,04674219 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02785881 0,04670962 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02785881 0,04667709 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02785881 0,04664461 ! steroid catabolic process GO:0006706 31 17 0,000 0,02785881 0,04661217 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02785881 0,04657978 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02785881 0,04654743 ! gas transport GO:0015669 25 17 0,000 0,02785881 0,04651513 ! organic cation transport GO:0015695 31 17 0,000 0,02785881 0,04648287 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02785881 0,04645066 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02785881 0,04641849 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02785881 0,04638637 ! microspike assembly GO:0030035 36 17 0,000 0,02785881 0,04635429 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02785881 0,04632225 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02785881 0,04629026 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02947366 0,04893971 ! neuron maturation GO:0042551 42 18 0,000 0,02947366 0,04890595 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02947366 0,04887225 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02947366 0,04883859 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02947366 0,04880498 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02947366 0,04877141 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02947366 0,04873789 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02947366 0,04870442 ! memory GO:0007613 31 18 0,000 0,02947366 0,04867099 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02947366 0,04863761 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02947366 0,04860427 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02947366 0,04857098 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02947366 0,04853774 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02947366 0,04850454 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02947366 0,04847138 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02947366 0,04843827 ! response to retinoic acid GO:0032526 26 18 0,000 0,02947366 0,04840521 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02947366 0,04837219 ! response to fungus GO:0009620 21 18 0,000 0,02947366 0,04833922 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02947366 0,04830629 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02947366 0,04827341 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02947366 0,04824057 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02947366 0,04820777 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02947366 0,04817502 ! vitamin transport GO:0051180 27 18 0,000 0,02947366 0,04814232 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02947366 0,04810966 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02947366 0,04807704 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02947366 0,04804447 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02947366 0,04801194 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02947366 0,04797945 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02947366 0,04794701 ! nerve development GO:0021675 28 18 0,000 0,02947366 0,04791462 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02947366 0,04788226 ! protein secretion GO:0009306 39 19 0,000 0,03108589 0,05046737 ! positive regulation of translation GO:0045727 30 19 0,000 0,03108589 0,05043334 ! negative regulation of defense response GO:0031348 25 19 0,000 0,03108589 0,05039936 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,03108589 0,05036542 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,03108589 0,05033152 ! skin development GO:0043588 36 19 0,000 0,03108589 0,05029768 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,03108589 0,05026387 ! lipid phosphorylation GO:0046834 35 19 0,000 0,03108589 0,05023012 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03108589 0,05019641 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,03108589 0,05016274 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,03108589 0,05012912 ! bile acid metabolic process GO:0008206 29 19 0,000 0,03108589 0,05009554 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,03108589 0,05006201 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,03108589 0,05002852 ! cerebral cortex development GO:0021987 36 19 0,000 0,03108589 0,04999508 ! pigmentation during development GO:0048066 41 19 0,000 0,03108589 0,04996169 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,03108589 0,04992833 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,03108589 0,04989503 ! heme metabolic process GO:0042168 36 19 0,000 0,03108589 0,04986176 ! actin filament bundle formation GO:0051017 42 19 0,000 0,03108589 0,04982854 ! neuromuscular junction development GO:0007528 34 19 0,000 0,03108589 0,04979537 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,03108589 0,04976224 ! plasma membrane fusion GO:0045026 28 19 0,000 0,03108589 0,04972915 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,03108589 0,04969611 ! peptide cross-linking GO:0018149 37 19 0,000 0,03108589 0,04966311 ! protein export from nucleus GO:0006611 36 19 0,000 0,03108589 0,04963016 ! heart process GO:0003015 30 19 0,000 0,03108589 0,04959724 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,03108589 0,04956438 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,03108589 0,04953155 ! visual learning GO:0008542 36 19 0,000 0,03108589 0,04949877 ! cellular pigmentation GO:0033059 36 19 0,000 0,03108589 0,04946603 ! G1 phase GO:0051318 40 19 0,000 0,03108589 0,04943334 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,03108589 0,04940069 ! cell-cell junction organization GO:0045216 35 19 0,000 0,03108589 0,04936808 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,03108589 0,04933552 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,03108589 0,049303 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,03108589 0,04927052 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,03108589 0,04923808 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,03108589 0,04920569 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,03108589 0,04917334 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,03108589 0,04914103 ! cilium assembly GO:0042384 37 19 0,000 0,03108589 0,04910876 ! peptide hormone secretion GO:0030072 31 19 0,000 0,03108589 0,04907654 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03269549 0,05158383 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03269549 0,05155003 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03269549 0,05151627 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03269549 0,05148255 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03269549 0,05144888 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03269549 0,05141525 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03269549 0,05138167 ! response to vitamin GO:0033273 31 20 0,000 0,03269549 0,05134813 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03269549 0,05131464 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,03269549 0,05128119 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03269549 0,05124778 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03269549 0,05121441 ! response to alkaloid GO:0043279 38 20 0,000 0,03269549 0,05118109 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03269549 0,05114781 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03269549 0,05111458 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,03269549 0,05108139 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03269549 0,05104824 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03269549 0,05101514 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03269549 0,05098207 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,03269549 0,05094905 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,03269549 0,05091608 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,03269549 0,05088314 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03269549 0,05085025 ! body fluid secretion GO:0007589 31 20 0,000 0,03269549 0,0508174 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03269549 0,0507846 ! peptide secretion GO:0002790 35 20 0,000 0,03269549 0,05075183 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03269549 0,05071911 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,03269549 0,05068643 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03269549 0,05065379 ! sensory perception of pain GO:0019233 30 20 0,000 0,03269549 0,0506212 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03269549 0,05058864 ! diencephalon development GO:0021536 34 20 0,000 0,03269549 0,05055613 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03269549 0,05052366 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03269549 0,05049123 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03269549 0,05045884 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03269549 0,0504265 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03269549 0,0503942 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03269549 0,05036193 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,03269549 0,05032971 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03269549 0,05029753 ! regulation of glucose import GO:0046324 29 20 0,000 0,03269549 0,05026539 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03269549 0,05023329 ! actin filament-based movement GO:0030048 43 20 0,000 0,03269549 0,05020124 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03269549 0,05016922 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03269549 0,05013725 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03269549 0,05010531 ! negative regulation of translation GO:0017148 29 20 0,000 0,03269549 0,05007342 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03269549 0,05004156 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,03269549 0,05000975 ! regulation of cell killing GO:0031341 42 21 0,000 0,03430246 0,05243439 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03430246 0,0524011 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03430246 0,05236785 ! hormone secretion GO:0046879 38 21 0,000 0,03430246 0,05233464 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03430246 0,05230148 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03430246 0,05226835 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03430246 0,05223527 ! axis specification GO:0009798 38 21 0,000 0,03430246 0,05220223 ! ovarian follicle development GO:0001541 35 21 0,000 0,03430246 0,05216923 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,03430246 0,05213628 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03430246 0,05210336 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03430246 0,05207049 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03430246 0,05203766 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03430246 0,05200487 ! cell aging GO:0007569 44 21 0,000 0,03430246 0,05197212 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03430246 0,05193941 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03430246 0,05190675 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03430246 0,05187412 ! cytolysis GO:0019835 24 21 0,000 0,03430246 0,05184154 ! vasodilation GO:0042311 39 21 0,000 0,03430246 0,05180899 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03430246 0,05177649 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,03430246 0,05174403 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03430246 0,05171161 ! oogenesis GO:0048477 36 21 0,000 0,03430246 0,05167923 ! DNA modification GO:0006304 34 21 0,000 0,03430246 0,05164689 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,03430246 0,05161459 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,03430246 0,05158233 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03430246 0,05155011 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,03430246 0,05151793 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03430246 0,05148579 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03430246 0,0514537 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03430246 0,05142164 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03430246 0,05138962 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03430246 0,05135764 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03430246 0,0513257 ! collagen catabolic process GO:0030574 28 21 0,000 0,03430246 0,0512938 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03430246 0,05126194 ! gut development GO:0048565 39 21 0,000 0,03430246 0,05123012 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,03590683 0,05359294 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,03590683 0,05355972 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,03590683 0,05352653 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,03590683 0,05349339 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,03590683 0,05346029 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,03590683 0,05342723 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,03590683 0,0533942 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,03590683 0,05336122 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,03590683 0,05332829 ! regeneration GO:0031099 41 22 0,000 0,03590683 0,05329539 ! keratinization GO:0031424 28 22 0,000 0,03590683 0,05326253 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,03590683 0,05322971 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,03590683 0,05319694 ! sensory perception of taste GO:0050909 28 22 0,000 0,03590683 0,0531642 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,03590683 0,0531315 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,03590683 0,05309885 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,03590683 0,05306623 ! vacuolar transport GO:0007034 36 22 0,000 0,03590683 0,05303365 ! lysosome organization GO:0007040 41 22 0,000 0,03590683 0,05300112 ! central nervous system neuron development GO:0021954 46 22 0,000 0,03590683 0,05296862 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,03590683 0,05293617 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,03590683 0,05290375 ! fucose metabolic process GO:0006004 39 22 0,000 0,03590683 0,05287137 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,03590683 0,05283904 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,03590683 0,05280674 ! ureteric bud development GO:0001657 43 22 0,000 0,03590683 0,05277448 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,03590683 0,05274226 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,03590683 0,05271008 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,03590683 0,05267794 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,03590683 0,05264584 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,03590683 0,05261378 ! sarcomere organization GO:0045214 30 22 0,000 0,03590683 0,05258175 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,03590683 0,05254977 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,03590683 0,05251783 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,03590683 0,05248592 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,03590683 0,05245405 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,03590683 0,05242222 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,03590683 0,05239043 ! protein stabilization GO:0050821 39 22 0,000 0,03590683 0,05235868 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,03750858 0,0546612 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,03750858 0,05462811 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,03750858 0,05459506 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,03750858 0,05456205 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,03750858 0,05452908 ! gluconeogenesis GO:0006094 33 23 0,000 0,03750858 0,05449616 ! viral genome replication GO:0019079 41 23 0,000 0,03750858 0,05446327 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,03750858 0,05443042 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,03750858 0,05439761 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,03750858 0,05436484 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,03750858 0,05433211 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,03750858 0,05429942 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,03750858 0,05426677 ! visual behavior GO:0007632 42 23 0,000 0,03750858 0,05423415 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,03750858 0,05420158 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,03750858 0,05416905 ! response to ethanol GO:0045471 46 23 0,000 0,03750858 0,05413655 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,03750858 0,0541041 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,03750858 0,05407168 ! peroxisome organization GO:0007031 37 23 0,000 0,03750858 0,0540393 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,03750858 0,05400696 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,03750858 0,05397466 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,03750858 0,0539424 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,03750858 0,05391018 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,03750858 0,05387799 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,03750858 0,05384584 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,03750858 0,05381373 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,03750858 0,05378166 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,03750858 0,05374963 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,03750858 0,05371764 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,03750858 0,05368568 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,03750858 0,05365377 ! fatty acid transport GO:0015908 44 23 0,000 0,03750858 0,05362189 ! platelet activation GO:0030168 37 23 0,000 0,03750858 0,05359004 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,03750858 0,05355824 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,03750858 0,05352647 ! hormone transport GO:0009914 40 23 0,000 0,03750858 0,05349474 ! cell-cell recognition GO:0009988 25 23 0,000 0,03750858 0,05346305 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,03750858 0,0534314 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,03750858 0,05339978 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,03750858 0,0533682 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,03750858 0,05333666 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,03750858 0,05330516 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,03910772 0,05554496 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,03910772 0,05551219 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03910772 0,05547946 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,03910772 0,05544677 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03910772 0,05541412 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03910772 0,0553815 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03910772 0,05534892 ! vesicle docking GO:0048278 47 24 0,000 0,03910772 0,05531638 ! spinal cord development GO:0021510 47 24 0,000 0,03910772 0,05528388 ! vacuole organization GO:0007033 43 24 0,000 0,03910772 0,05525142 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03910772 0,055219 ! digestive system process GO:0022600 39 24 0,000 0,03910772 0,05518661 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03910772 0,05515426 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03910772 0,05512195 ! regulation of behavior GO:0050795 43 24 0,000 0,03910772 0,05508968 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03910772 0,05505744 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03910772 0,05502524 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03910772 0,05499308 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,03910772 0,05496096 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03910772 0,05492888 ! membrane depolarization GO:0051899 39 24 0,000 0,03910772 0,05489683 ! pallium development GO:0021543 49 24 0,000 0,03910772 0,05486482 ! pentose metabolic process GO:0019321 35 24 0,000 0,03910772 0,05483285 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,03910772 0,05480091 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03910772 0,05476902 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03910772 0,05473715 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03910772 0,05470533 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03910772 0,05467354 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03910772 0,05464179 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,03910772 0,05461008 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03910772 0,0545784 ! regulation of amine transport GO:0051952 40 24 0,000 0,03910772 0,05454676 ! protein tetramerization GO:0051262 52 24 0,000 0,03910772 0,05451516 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,04070426 0,05670784 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,04070426 0,05667502 ! myelination GO:0042552 45 25 0,000 0,04070426 0,05664224 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,04070426 0,0566095 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,04070426 0,0565768 ! phototransduction GO:0007602 33 25 0,000 0,04070426 0,05654413 ! vasculogenesis GO:0001570 46 25 0,000 0,04070426 0,05651151 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,04070426 0,05647891 ! sperm motility GO:0030317 31 25 0,000 0,04070426 0,05644636 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,04070426 0,05641385 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,04070426 0,05638137 ! receptor metabolic process GO:0043112 46 25 0,000 0,04070426 0,05634893 ! chromosome condensation GO:0030261 45 25 0,000 0,04070426 0,05631653 ! response to starvation GO:0042594 42 25 0,000 0,04070426 0,05628416 ! neural crest cell development GO:0014032 54 25 0,000 0,04070426 0,05625183 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,04070426 0,05621954 ! negative regulation of cell development GO:0010721 73 25 0,000 0,04070426 0,05618729 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,04070426 0,05615507 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,04070426 0,05612289 ! interaction with host GO:0051701 62 25 0,000 0,04070426 0,05609074 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,04070426 0,05605864 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,04070426 0,05602657 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,04070426 0,05599453 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,04070426 0,05596254 ! immunoglobulin production GO:0002377 55 25 0,000 0,04070426 0,05593058 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,04070426 0,05589865 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,04070426 0,05586676 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,04070426 0,05583491 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,04070426 0,0558031 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,04070426 0,05577132 ! telomere organization GO:0032200 43 25 0,000 0,04070426 0,05573958 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,04070426 0,05570787 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,04070426 0,0556762 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,04229819 0,05782355 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,04229819 0,05779072 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,04229819 0,05775792 ! initiation of viral infection GO:0019059 57 26 0,000 0,04229819 0,05772516 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,04229819 0,05769243 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,04229819 0,05765975 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,04229819 0,0576271 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,04229819 0,05759448 ! molting cycle process GO:0022404 50 26 0,000 0,04229819 0,05756191 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,04229819 0,05752937 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,04229819 0,05749687 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,04229819 0,0574644 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,04229819 0,05743197 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,04229819 0,05739958 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,04229819 0,05736722 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,04229819 0,0573349 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,04229819 0,05730262 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,04229819 0,05727037 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,04229819 0,05723816 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,04229819 0,05720599 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,04229819 0,05717385 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,04229819 0,05714175 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,04229819 0,05710968 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,04229819 0,05707765 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,04229819 0,05704566 ! leukocyte proliferation GO:0070661 52 26 0,000 0,04229819 0,0570137 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,04229819 0,05698178 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,04229819 0,05694989 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,04388954 0,05905941 ! neuron fate commitment GO:0048663 48 27 0,000 0,04388954 0,0590264 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,04388954 0,05899342 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,04388954 0,05896048 ! iron ion transport GO:0006826 59 27 0,000 0,04388954 0,05892758 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,04388954 0,05889471 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,04388954 0,05886189 ! protein amino acid acylation GO:0043543 55 27 0,000 0,04388954 0,05882909 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,04388954 0,05879634 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,04388954 0,05876362 ! fat cell differentiation GO:0045444 50 27 0,000 0,04388954 0,05873094 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,04388954 0,05869829 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,04388954 0,05866568 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,04388954 0,05863311 ! autophagy GO:0006914 41 27 0,000 0,04388954 0,05860057 ! male gonad development GO:0008584 44 27 0,000 0,04388954 0,05856807 ! response to toxin GO:0009636 47 27 0,000 0,04388954 0,0585356 ! primary neural tube formation GO:0014020 51 27 0,000 0,04388954 0,05850317 ! base-excision repair GO:0006284 41 27 0,000 0,04388954 0,05847078 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,04388954 0,05843842 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,04388954 0,0584061 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,04388954 0,05837381 ! glutathione metabolic process GO:0006749 39 27 0,000 0,04388954 0,05834156 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,04388954 0,05830935 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,04388954 0,05827717 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,04388954 0,05824502 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,04388954 0,05821291 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,04547829 0,06028692 ! circadian rhythm GO:0007623 50 28 0,000 0,04547829 0,06025372 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,04547829 0,06022056 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,04547829 0,06018744 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,04547829 0,06015435 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,04547829 0,0601213 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,04547829 0,06008828 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,04547829 0,0600553 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,04547829 0,06002236 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,04547829 0,05998945 ! synaptogenesis GO:0007416 42 28 0,000 0,04547829 0,05995658 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,04547829 0,05992375 ! lipid oxidation GO:0034440 43 28 0,000 0,04547829 0,05989095 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,04547829 0,05985818 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,04547829 0,05982546 ! translational initiation GO:0006413 65 29 0,000 0,04706445 0,06187818 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,04706445 0,06184439 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,04706445 0,06181063 ! regulation of pH GO:0006885 43 29 0,000 0,04706445 0,06177691 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,04706445 0,06174322 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,04706445 0,06170957 ! catechol metabolic process GO:0009712 54 29 0,000 0,04706445 0,06167596 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,04706445 0,06164239 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,04706445 0,06160885 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,04706445 0,06157535 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,04706445 0,06154189 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,04706445 0,06150846 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,04706445 0,06147506 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,04706445 0,06144171 ! detection of light stimulus GO:0009583 38 29 0,000 0,04706445 0,06140839 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,04706445 0,06137511 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,04706445 0,06134186 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,04706445 0,06130865 ! tissue homeostasis GO:0001894 48 29 0,000 0,04706445 0,06127547 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,04706445 0,06124233 ! phenol metabolic process GO:0018958 55 30 0,000 0,04864803 0,06326874 ! zinc ion transport GO:0006829 45 30 0,000 0,04864803 0,06323456 ! membrane docking GO:0022406 61 30 0,000 0,04864803 0,06320041 ! cell junction assembly GO:0034329 78 30 0,000 0,04864803 0,06316631 ! regulation of innate immune response GO:0045088 51 30 0,000 0,04864803 0,06313224 ! acute-phase response GO:0006953 49 30 0,000 0,04864803 0,0630982 ! myofibril assembly GO:0030239 47 30 0,000 0,04864803 0,06306421 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,04864803 0,06303024 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,04864803 0,06299632 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,04864803 0,06296243 ! phospholipid transport GO:0015914 51 30 0,000 0,04864803 0,06292858 ! ensheathment of neurons GO:0007272 57 30 0,000 0,04864803 0,06289477 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,04864803 0,06286099 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,04864803 0,06282725 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,04864803 0,06279354 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,04864803 0,06275987 ! eye morphogenesis GO:0048592 60 30 0,000 0,04864803 0,06272624 ! regulation of B cell activation GO:0050864 50 30 0,000 0,04864803 0,06269264 ! response to heat GO:0009408 50 30 0,000 0,04864803 0,06265908 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,05022903 0,06466081 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,05022903 0,06462623 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,05022903 0,06459169 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,05022903 0,06455719 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,05022903 0,06452272 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,05022903 0,06448829 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,05022903 0,0644539 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,05022903 0,06441954 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,05022903 0,06438522 ! ovulation cycle process GO:0022602 49 31 0,000 0,05022903 0,06435093 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,05022903 0,06431669 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,05022903 0,06428248 ! peptide transport GO:0015833 55 31 0,000 0,05022903 0,0642483 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,05022903 0,06421416 ! iron ion homeostasis GO:0055072 54 31 0,000 0,05022903 0,06418006 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,05022903 0,064146 ! natural killer cell activation GO:0030101 45 31 0,000 0,05022903 0,06411197 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,05022903 0,06407797 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,05022903 0,06404401 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,05022903 0,06401009 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,05022903 0,06397621 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,05022903 0,06394236 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,05180746 0,06591684 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,05180746 0,065882 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,05180746 0,0658472 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,05180746 0,06581243 ! cholesterol transport GO:0030301 56 32 0,000 0,05180746 0,0657777 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,05180746 0,06574301 ! spliceosome assembly GO:0000245 67 32 0,000 0,05180746 0,06570836 ! spindle organization GO:0007051 46 32 0,000 0,05180746 0,06567374 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,05180746 0,06563915 ! metanephros development GO:0001656 74 32 0,000 0,05180746 0,06560461 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,05180746 0,06557009 ! response to ionizing radiation GO:0010212 65 32 0,000 0,05180746 0,06553562 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,05180746 0,06550118 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,05180746 0,06546678 ! muscle cell development GO:0055001 49 32 0,000 0,05180746 0,06543241 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,05180746 0,06539808 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,05180746 0,06536379 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,05180746 0,06532953 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,05180746 0,06529531 ! ovulation cycle GO:0042698 51 32 0,000 0,05180746 0,06526113 ! peripheral nervous system development GO:0007422 64 32 0,000 0,05180746 0,06522698 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,05180746 0,06519286 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,05180746 0,06515878 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,05180746 0,06512474 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,05338332 0,06707063 ! post-embryonic development GO:0009791 69 33 0,000 0,05338332 0,06703563 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,05338332 0,06700066 ! protein targeting to membrane GO:0006612 68 33 0,000 0,05338332 0,06696572 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,05338332 0,06693083 ! ceramide metabolic process GO:0006672 64 33 0,000 0,05338332 0,06689597 ! cell fate specification GO:0001708 52 33 0,000 0,05338332 0,06686114 ! sterol transport GO:0015918 57 33 0,000 0,05338332 0,06682636 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,05338332 0,06679161 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,05338332 0,06675689 ! adult locomotory behavior GO:0008344 59 33 0,000 0,05338332 0,06672221 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,05338332 0,06668757 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,05338332 0,06665296 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,05495661 0,06858174 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,05495661 0,06854619 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,05495661 0,06851067 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,05495661 0,06847519 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,05495661 0,06843975 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,05495661 0,06840434 ! mismatch repair GO:0006298 46 34 0,000 0,05495661 0,06836897 ! spermatid development GO:0007286 63 34 0,000 0,05495661 0,06833364 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,05495661 0,06829834 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,05495661 0,06826308 ! placenta development GO:0001890 53 34 0,000 0,05495661 0,06822786 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,05495661 0,06819267 ! regulation of muscle development GO:0048634 70 35 0,000 0,05652733 0,07010555 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,05652733 0,07006943 ! negative regulation of secretion GO:0051048 63 35 0,000 0,05652733 0,07003335 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,05652733 0,0699973 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,05652733 0,0699613 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,05652733 0,06992533 ! odontogenesis GO:0042476 66 35 0,000 0,05652733 0,06988939 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,05652733 0,0698535 ! female gonad development GO:0008585 58 35 0,000 0,05652733 0,06981764 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,05652733 0,06978182 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,05652733 0,06974603 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,05652733 0,06971028 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,05652733 0,06967457 ! cytokine production GO:0001816 59 35 0,000 0,05652733 0,06963889 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,05652733 0,06960326 ! neural tube formation GO:0001841 67 35 0,000 0,05652733 0,06956765 ! vesicle localization GO:0051648 64 35 0,000 0,05652733 0,06953209 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,0580955 0,07142451 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,0580955 0,07138804 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,0580955 0,07135159 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,0580955 0,07131519 ! cell junction organization GO:0034330 86 36 0,000 0,0580955 0,07127882 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,0580955 0,07124249 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,0580955 0,0712062 ! positive regulation of cell development GO:0010720 80 36 0,000 0,0580955 0,07116995 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,0580955 0,07113373 ! regulation of proteolysis GO:0030162 72 36 0,000 0,0580955 0,07109755 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,0580955 0,0710614 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,0580955 0,07102529 ! aerobic respiration GO:0009060 55 36 0,000 0,0580955 0,07098922 ! embryonic organ development GO:0048568 57 36 0,000 0,0580955 0,07095318 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,0580955 0,07091719 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,0580955 0,07088122 ! RNA export from nucleus GO:0006405 56 37 0,000 0,05966111 0,07275451 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,05966111 0,07271765 ! meiosis I GO:0007127 65 37 0,000 0,05966111 0,07268083 ! sister chromatid segregation GO:0000819 58 37 0,000 0,05966111 0,07264405 ! actomyosin structure organization GO:0031032 62 37 0,000 0,05966111 0,0726073 ! organic anion transport GO:0015711 68 37 0,000 0,05966111 0,0725706 ! tissue remodeling GO:0048771 76 37 0,000 0,05966111 0,07253393 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,05966111 0,07249729 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,05966111 0,0724607 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,05966111 0,07242414 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,05966111 0,07238761 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,05966111 0,07235113 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,05966111 0,07231468 ! pigment metabolic process GO:0042440 80 37 0,000 0,05966111 0,07227827 ! spermatid differentiation GO:0048515 66 37 0,000 0,05966111 0,07224189 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,05966111 0,07220555 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,06122418 0,07406002 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,06122418 0,0740228 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,06122418 0,07398562 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,06122418 0,07394848 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,06122418 0,07391138 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,06122418 0,07387431 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,06122418 0,07383728 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,06122418 0,07380029 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,06122418 0,07376333 ! lipid homeostasis GO:0055088 67 38 0,000 0,06122418 0,07372641 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,06122418 0,07368953 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,06122418 0,07365269 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,06122418 0,07361588 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,06122418 0,07357911 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,06122418 0,07354237 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,06122418 0,07350567 ! mRNA catabolic process GO:0006402 71 39 0,000 0,06278469 0,07534163 ! mammary gland development GO:0030879 86 39 0,000 0,06278469 0,07530408 ! learning GO:0007612 77 39 0,000 0,06278469 0,07526655 ! ear morphogenesis GO:0042471 60 39 0,000 0,06278469 0,07522907 ! organic ether metabolic process GO:0018904 55 39 0,000 0,06278469 0,07519163 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,06278469 0,07515422 ! segmentation GO:0035282 67 39 0,000 0,06278469 0,07511684 ! ion transmembrane transport GO:0034220 66 39 0,000 0,06278469 0,07507951 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,06278469 0,07504221 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,06278469 0,07500495 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,06278469 0,07496773 ! RNA modification GO:0009451 57 39 0,000 0,06278469 0,07493054 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,06434267 0,07675184 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,06434267 0,07671381 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,06434267 0,07667581 ! feeding behavior GO:0007631 59 40 0,000 0,06434267 0,07663785 ! negative regulation of binding GO:0051100 72 40 0,000 0,06434267 0,07659993 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,06434267 0,07656205 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,06434267 0,0765242 ! maintenance of protein location GO:0045185 91 40 0,000 0,06434267 0,07648639 ! cytokinesis GO:0000910 72 40 0,000 0,06434267 0,07644862 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,06589811 0,07825807 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,06589811 0,07821946 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,06589811 0,07818089 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,06589811 0,07814236 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,06589811 0,07810386 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,06589811 0,07806541 ! T cell differentiation GO:0030217 81 41 0,000 0,06589811 0,07802699 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,06589811 0,07798861 ! female gamete generation GO:0007292 61 41 0,000 0,06589811 0,07795027 ! polyol metabolic process GO:0019751 66 41 0,000 0,06589811 0,07791196 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,06589811 0,07787369 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,06745101 0,07966967 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,06745101 0,07963058 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,06745101 0,07959153 ! regulation of tube size GO:0035150 71 42 0,000 0,06745101 0,07955251 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,06745101 0,07951354 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,06745101 0,0794746 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,06745101 0,0794357 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,06745101 0,07939683 ! neuron migration GO:0001764 79 42 0,000 0,06745101 0,07935801 ! regulation of protein secretion GO:0050708 71 42 0,000 0,06745101 0,07931922 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,06745101 0,07928047 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,06900138 0,08106315 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,06900138 0,08102358 ! glucose transport GO:0015758 65 43 0,000 0,06900138 0,08098406 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,06900138 0,08094457 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,06900138 0,08090513 ! neural tube development GO:0021915 77 43 0,000 0,06900138 0,08086572 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,06900138 0,08082635 ! striated muscle contraction GO:0006941 77 43 0,000 0,06900138 0,08078702 ! phagocytosis GO:0006909 90 43 0,000 0,06900138 0,08074772 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,06900138 0,08070847 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,07054923 0,08247883 ! hexose transport GO:0008645 67 44 0,000 0,07054923 0,08243878 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,07054923 0,08239876 ! male sex differentiation GO:0046661 76 44 0,000 0,07054923 0,08235878 ! double-strand break repair GO:0006302 81 44 0,000 0,07054923 0,08231884 ! B cell differentiation GO:0030183 107 44 0,000 0,07054923 0,08227893 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,07054923 0,08223907 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,07054923 0,08219924 ! maintenance of location in cell GO:0051651 97 44 0,000 0,07054923 0,08215946 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,07209455 0,08391848 ! glycolysis GO:0006096 65 45 0,000 0,07209455 0,0838779 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,07209455 0,08383736 ! leukocyte migration GO:0050900 68 45 0,000 0,07209455 0,08379686 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,07209455 0,08375639 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,07209455 0,08371597 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,07209455 0,08367559 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,07209455 0,08363524 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,07209455 0,08359494 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,07209455 0,08355467 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,07209455 0,08351444 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,07209455 0,08347425 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,07363736 0,08521957 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,07363736 0,0851786 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,07363736 0,08513767 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,07363736 0,08509677 ! pigmentation GO:0043473 100 46 0,000 0,07363736 0,08505592 ! response to insulin stimulus GO:0032868 95 46 0,000 0,07363736 0,08501511 ! positive regulation of defense response GO:0031349 76 47 0,000 0,07517765 0,08675176 ! response to calcium ion GO:0051592 81 47 0,000 0,07517765 0,08671018 ! endosome transport GO:0016197 108 47 0,000 0,07517765 0,08666863 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,07517765 0,08662712 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,07517765 0,08658565 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,07517765 0,08654422 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,07517765 0,08650283 ! JNK cascade GO:0007254 91 47 0,000 0,07517765 0,08646148 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,07517765 0,08642017 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,07671543 0,08814581 ! mitochondrial transport GO:0006839 82 48 0,000 0,07671543 0,08810374 ! cellular component disassembly GO:0022411 86 48 0,000 0,07671543 0,0880617 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,07671543 0,08801971 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,07671543 0,08797776 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,07671543 0,08793584 ! activation of caspase activity GO:0006919 84 48 0,000 0,07671543 0,08789397 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,07671543 0,08785213 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,07671543 0,08781034 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,07671543 0,08776858 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,07671543 0,08772687 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,07825071 0,08944 ! regulation of action potential GO:0001508 95 49 0,000 0,07825071 0,08939753 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,07825071 0,0893551 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,07825071 0,08931272 ! regulation of ion transport GO:0043269 77 49 0,000 0,07825071 0,08927037 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,07825071 0,08922806 ! peptide metabolic process GO:0006518 76 49 0,000 0,07825071 0,08918579 ! response to temperature stimulus GO:0009266 76 49 0,000 0,07825071 0,08914356 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,07825071 0,08910138 ! endocrine system development GO:0035270 104 49 0,000 0,07825071 0,08905923 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,07825071 0,08901712 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,07825071 0,08897505 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,07825071 0,08893302 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,07825071 0,08889103 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,07978348 0,09058946 ! neuromuscular process GO:0050905 99 50 0,000 0,07978348 0,09054673 ! inner ear development GO:0048839 79 50 0,000 0,07978348 0,09050404 ! histone modification GO:0016570 91 50 0,000 0,07978348 0,09046139 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,07978348 0,09041878 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,07978348 0,09037621 ! positive regulation of binding GO:0051099 78 51 0,000 0,08131376 0,09206631 ! viral infectious cycle GO:0019058 99 51 0,000 0,08131376 0,092023 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,08131376 0,09197974 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,08131376 0,09193652 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,08131376 0,09189333 ! excretion GO:0007588 83 51 0,000 0,08131376 0,09185019 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,08131376 0,09180709 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,08131376 0,09176403 ! vesicle organization GO:0016050 107 51 0,000 0,08131376 0,09172101 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,08131376 0,09167803 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,08131376 0,09163509 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,08131376 0,09159218 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,08284154 0,09326942 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,08284154 0,0932258 ! membrane fusion GO:0006944 110 52 0,000 0,08284154 0,09318221 ! positive regulation of growth GO:0045927 90 52 0,000 0,08284154 0,09313867 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,08284154 0,09309517 ! amino acid activation GO:0043038 92 52 0,000 0,08284154 0,0930517 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,08284154 0,09300828 ! synapse organization GO:0050808 85 52 0,000 0,08284154 0,0929649 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,08436684 0,09463245 ! RNA catabolic process GO:0006401 93 53 0,000 0,08436684 0,09458835 ! regulation of translational initiation GO:0006446 82 53 0,000 0,08436684 0,0945443 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,08436684 0,09450028 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,08436684 0,09445631 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,08436684 0,09441237 ! cell maturation GO:0048469 100 53 0,000 0,08436684 0,09436848 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,08436684 0,09432463 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,08436684 0,09428082 ! response to UV GO:0009411 104 53 0,000 0,08436684 0,09423705 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,08588964 0,09589349 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,08588964 0,09584902 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,08588964 0,09580458 ! cell recognition GO:0008037 85 54 0,000 0,08588964 0,09576018 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,08588964 0,09571583 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,08588964 0,09567152 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,08588964 0,09562725 ! chloride transport GO:0006821 90 55 0,000 0,08740997 0,09727492 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,08740997 0,09722995 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,08740997 0,09718502 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,08740997 0,09714013 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,08740997 0,09709528 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,08740997 0,09705048 ! aging GO:0007568 103 55 0,000 0,08740997 0,09700571 ! heart morphogenesis GO:0003007 97 55 0,000 0,08740997 0,09696099 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,08740997 0,0969163 ! nuclear export GO:0051168 97 55 0,000 0,08740997 0,09687166 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,08740997 0,09682706 ! regulation of actin filament length GO:0030832 105 56 0,000 0,08892781 0,0984631 ! sensory perception of smell GO:0007608 80 56 0,000 0,08892781 0,09841781 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,08892781 0,09837256 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,08892781 0,09832735 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,08892781 0,09828219 ! regulation of DNA replication GO:0006275 101 56 0,000 0,08892781 0,09823706 ! proton transport GO:0015992 94 56 0,000 0,08892781 0,09819198 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,08892781 0,09814693 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,09044319 0,09977364 ! muscle fiber development GO:0048747 112 57 0,000 0,09044319 0,09972791 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,09044319 0,09968223 ! lipid modification GO:0030258 97 57 0,000 0,09044319 0,09963659 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,09044319 0,09959099 ! maintenance of location GO:0051235 118 57 0,000 0,09044319 0,09954543 ! hydrogen transport GO:0006818 97 58 0,000 0,09195609 0,10116431 ! regulation of endocytosis GO:0030100 91 58 0,000 0,09195609 0,10111807 ! adult behavior GO:0030534 99 58 0,000 0,09195609 0,10107188 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,09195609 0,10102573 ! positive regulation of secretion GO:0051047 95 59 0,000 0,09346652 0,10263827 ! regulation of cellular component size GO:0032535 109 59 0,000 0,09346652 0,10259145 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,09346652 0,10254467 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,09346652 0,10249793 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,09346652 0,10245123 ! DNA catabolic process GO:0006308 86 59 0,000 0,09346652 0,10240458 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,09346652 0,10235797 ! establishment of organelle localization GO:0051656 109 59 0,000 0,09346652 0,1023114 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,0949745 0,1039148 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,0949745 0,10386756 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,0949745 0,10382037 ! regulation of heart contraction GO:0008016 110 60 0,000 0,0949745 0,10377322 ! camera-type eye development GO:0043010 116 60 0,000 0,0949745 0,10372612 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,0949745 0,10367906 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,0949745 0,10363204 ! kidney development GO:0001822 122 60 0,000 0,0949745 0,10358506 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,09648001 0,10517939 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,09648001 0,10513175 ! tRNA processing GO:0008033 89 61 0,000 0,09648001 0,10508416 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,09648001 0,10503661 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,09648001 0,1049891 ! ear development GO:0043583 103 62 0,000 0,09798307 0,10657653 ! viral reproductive process GO:0022415 126 62 0,000 0,09798307 0,10652837 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,09798307 0,10648025 ! gonad development GO:0008406 98 62 0,000 0,09798307 0,10643218 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,09798307 0,10638415 ! regulation of mitosis GO:0007088 105 63 0,000 0,09948368 0,1079647 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,09948368 0,10791603 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,09948368 0,10786739 ! detection of external stimulus GO:0009581 91 63 0,000 0,09948368 0,1078188 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,09948368 0,10777026 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,10098185 0,10934398 ! cell redox homeostasis GO:0045454 102 64 0,000 0,10098185 0,10929479 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,10098185 0,10924565 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,10098185 0,10919655 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,10098185 0,1091475 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,10098185 0,10909848 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,10247757 0,11066474 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,10247757 0,11061509 ! germ cell development GO:0007281 118 65 0,000 0,10247757 0,11056548 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,10247757 0,11051593 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,10397085 0,11207611 ! actin filament organization GO:0007015 148 66 0,000 0,10397085 0,11202592 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,10397085 0,11197577 ! extracellular matrix organization GO:0030198 133 66 0,000 0,10397085 0,11192567 ! secondary metabolic process GO:0019748 116 66 0,000 0,10397085 0,11187561 ! developmental maturation GO:0021700 116 66 0,000 0,10397085 0,1118256 ! cell projection assembly GO:0030031 120 66 0,000 0,10397085 0,11177563 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,1054617 0,11332776 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,1054617 0,11327716 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,1054617 0,11322662 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,1054617 0,11317611 ! activation of MAPK activity GO:0000187 115 67 0,000 0,1054617 0,11312566 ! lung development GO:0030324 144 67 0,000 0,1054617 0,11307524 ! chromosome segregation GO:0007059 113 67 0,000 0,1054617 0,11302488 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,1054617 0,11297455 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,1054617 0,11292428 ! hexose catabolic process GO:0019320 104 67 0,000 0,1054617 0,11287404 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,1054617 0,11282385 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,1054617 0,11277371 ! adaptive immune response GO:0002250 119 67 0,000 0,1054617 0,11272361 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,1054617 0,11267356 ! amino acid transport GO:0006865 125 68 0,000 0,10695012 0,11421304 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,10695012 0,11416237 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,10695012 0,11411174 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,10695012 0,11406116 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,10695012 0,11401062 ! regulation of lipase activity GO:0060191 130 68 0,000 0,10695012 0,11396013 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,10695012 0,11390968 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,10695012 0,11385928 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,1084361 0,11539021 ! negative regulation of cell size GO:0045792 134 69 0,000 0,1084361 0,1153392 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,1084361 0,11528823 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,1084361 0,11523731 ! urogenital system development GO:0001655 137 69 0,000 0,1084361 0,11518643 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,1084361 0,1151356 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,1084361 0,11508481 ! antigen processing and presentation GO:0019882 104 69 0,000 0,1084361 0,11503407 ! respiratory tube development GO:0030323 150 70 0,000 0,10991967 0,11655651 ! amine catabolic process GO:0009310 117 71 0,000 0,11140082 0,11807505 ! reproductive structure development GO:0048608 113 71 0,000 0,11140082 0,11802306 ! humoral immune response GO:0006959 109 71 0,000 0,11140082 0,11797111 ! B cell activation GO:0042113 160 71 0,000 0,11140082 0,11791921 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,11140082 0,11786736 ! regulation of immune effector process GO:0002697 137 71 0,000 0,11140082 0,11781555 ! acute inflammatory response GO:0002526 113 72 0,000 0,11287955 0,11932697 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,11287955 0,11927457 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,11287955 0,11922221 ! carbohydrate transport GO:0008643 110 72 0,000 0,11287955 0,1191699 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,11287955 0,11911763 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,11287955 0,11906541 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,11287955 0,11901323 ! respiratory system development GO:0060541 153 72 0,000 0,11287955 0,1189611 ! learning or memory GO:0007611 147 73 0,000 0,11435587 0,12046419 ! regulation of blood pressure GO:0008217 125 73 0,000 0,11435587 0,12041147 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,11435587 0,1203588 ! axon guidance GO:0007411 139 73 0,000 0,11435587 0,12030617 ! fertilization GO:0009566 90 73 0,000 0,11435587 0,12025359 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,11582978 0,12175031 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,11582978 0,12169714 ! neurotransmitter transport GO:0006836 123 74 0,000 0,11582978 0,12164402 ! meiosis GO:0007126 121 74 0,000 0,11582978 0,12159095 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,11582978 0,12153792 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,11582978 0,12148494 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,11582978 0,121432 ! eye development GO:0001654 143 74 0,000 0,11582978 0,12137912 ! organelle localization GO:0051640 136 74 0,000 0,11582978 0,12132627 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,11730129 0,12281414 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,11730129 0,12276072 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,11730129 0,12270735 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,11730129 0,12265402 ! meiotic cell cycle GO:0051321 122 75 0,000 0,11730129 0,12260074 ! rhythmic process GO:0048511 128 75 0,000 0,11730129 0,1225475 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,11730129 0,12249431 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,1187704 0,12397465 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,1187704 0,12392089 ! defense response to bacterium GO:0042742 89 76 0,000 0,1187704 0,12386717 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,1187704 0,12381351 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,1187704 0,12375988 ! regulation of catabolic process GO:0009894 161 76 0,000 0,1187704 0,12370631 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,12023711 0,12517978 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,12023711 0,12512564 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,12023711 0,12507154 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,12023711 0,12501749 ! blood coagulation GO:0007596 146 78 0,000 0,12170143 0,12648537 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,12170143 0,12643076 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,12170143 0,12637619 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,12316336 0,1278391 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,12316336 0,12778397 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,12316336 0,1277289 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,12316336 0,12767386 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,1246229 0,12913122 ! response to metal ion GO:0010038 140 80 0,000 0,1246229 0,12907564 ! muscle cell differentiation GO:0042692 159 80 0,000 0,1246229 0,1290201 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,1246229 0,1289646 ! protein import into nucleus GO:0006606 158 80 0,000 0,1246229 0,12890916 ! inorganic anion transport GO:0015698 138 80 0,000 0,1246229 0,12885376 ! T cell activation GO:0042110 168 81 0,000 0,12608007 0,1303044 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,12608007 0,13024845 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,12608007 0,13019255 ! digestion GO:0007586 112 81 0,000 0,12608007 0,1301367 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,12608007 0,13008089 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,12608007 0,13002514 ! nuclear import GO:0051170 161 81 0,000 0,12608007 0,12996943 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,12608007 0,12991377 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,12753485 0,13135653 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,12753485 0,13130033 ! response to drug GO:0042493 143 82 0,000 0,12753485 0,13124417 ! response to nutrient GO:0007584 125 82 0,000 0,12753485 0,13118805 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,12753485 0,13113199 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,12753485 0,13107598 ! response to oxygen levels GO:0070482 176 83 0,000 0,12898727 0,13251211 ! regulation of lyase activity GO:0051339 160 83 0,000 0,12898727 0,13245556 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,13043731 0,13388745 ! hemostasis GO:0007599 158 84 0,000 0,13043731 0,13383035 ! negative regulation of transport GO:0051051 153 84 0,000 0,13043731 0,13377331 ! negative regulation of growth GO:0045926 155 84 0,000 0,13043731 0,13371631 ! regulation of ligase activity GO:0051340 142 84 0,000 0,13043731 0,13365936 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,13043731 0,13360246 ! response to unfolded protein GO:0006986 131 85 0,000 0,13188499 0,13502778 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,13188499 0,13497035 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,13333031 0,13639146 ! response to inorganic substance GO:0010035 153 86 0,000 0,13333031 0,1363335 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,13333031 0,13627558 ! tube morphogenesis GO:0035239 176 86 0,000 0,13333031 0,13621772 ! mitochondrion organization GO:0007005 148 86 0,000 0,13333031 0,1361599 ! alcohol catabolic process GO:0046164 130 86 0,000 0,13333031 0,13610213 ! amine transport GO:0015837 155 86 0,000 0,13333031 0,13604441 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,13477327 0,13745845 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,13477327 0,1374002 ! protein localization in nucleus GO:0034504 176 87 0,000 0,13477327 0,13734201 ! cellular respiration GO:0045333 135 88 0,000 0,13621387 0,1387513 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,13621387 0,13869258 ! regulation of DNA binding GO:0051101 155 88 0,000 0,13621387 0,13863391 ! gland development GO:0048732 206 88 0,000 0,13621387 0,1385753 ! regulation of neurological system process GO:0031644 148 88 0,000 0,13621387 0,13851673 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,13621387 0,13845821 ! cellular defense response GO:0006968 114 89 0,000 0,13765212 0,13986107 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,13765212 0,13980203 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,13765212 0,13974304 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,13908803 0,14114121 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,13908803 0,1410817 ! sex differentiation GO:0007548 145 90 0,000 0,13908803 0,14102225 ! sterol metabolic process GO:0016125 152 91 0,000 0,14052159 0,14241573 ! response to protein stimulus GO:0051789 149 91 0,000 0,14052159 0,14235577 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,14052159 0,14229586 ! regulation of defense response GO:0031347 149 92 0,000 0,14195282 0,14368468 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,14195282 0,14362425 ! vitamin metabolic process GO:0006766 139 92 0,000 0,14195282 0,14356388 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,14338171 0,14494806 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,14338171 0,14488718 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,14338171 0,14482636 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,14338171 0,14476558 ! regulation of membrane potential GO:0042391 164 93 0,000 0,14338171 0,14470486 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,14338171 0,14464419 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,14480826 0,14602208 ! female pregnancy GO:0007565 164 94 0,000 0,14480826 0,1459609 ! regulation of T cell activation GO:0050863 158 94 0,000 0,14480826 0,14589978 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,14623249 0,14727307 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,14623249 0,14721145 ! leukocyte differentiation GO:0002521 202 96 0,000 0,14765439 0,14858071 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,14765439 0,14851859 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,14765439 0,14845653 ! positive regulation of immune response GO:0050778 156 96 0,000 0,14765439 0,14839451 ! detection of stimulus GO:0051606 151 96 0,000 0,14765439 0,14833255 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,14907397 0,14969615 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,14907397 0,1496337 ! protein ubiquitination GO:0016567 217 97 0,000 0,14907397 0,1495713 ! hormone metabolic process GO:0042445 157 97 0,000 0,14907397 0,14950895 ! response to virus GO:0009615 160 98 0,000 0,15049124 0,15086747 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,15049124 0,15080463 ! interphase GO:0051325 213 98 0,000 0,15049124 0,15074185 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,15049124 0,15067912 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,15190619 0,15203257 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,15190619 0,15196935 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,15190619 0,15190619 GO:0060538|skeletal muscle organ development,