pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/10-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 3,000 1,557E-09 3,804E-06 ! BMP signaling pathway GO:0030509 71 32 3,000 1,657E-07 2,024E-04 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 3,000 5,617E-07 4,574E-04 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 1,489E-06 9,092E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 3,71E-06 1,813E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 5,001E-06 2,036E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 3,000 6,906E-06 2,41E-03 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 2,000 1,307E-05 3,992E-03 ! cell fate determination GO:0001709 64 30 2,000 1,307E-05 3,548E-03 ! transcription initiation GO:0006352 171 97 3,000 1,484E-05 3,626E-03 ! hindbrain development GO:0030902 65 32 2,000 1,593E-05 3,539E-03 ! glial cell fate commitment GO:0021781 14 5 1,000 2,259E-05 4,599E-03 ! protein maturation by protein folding GO:0022417 14 5 1,000 2,259E-05 4,245E-03 ! ATP-dependent chromatin remodeling GO:0043044 10 5 1,000 2,259E-05 3,942E-03 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 2,483E-05 4,044E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 3,385E-05 5,168E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 3,392E-05 4,874E-03 ! mesenchymal cell development GO:0014031 94 41 2,000 3,392E-05 4,603E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of intracellular protein transport GO:0033157 86 42 2,000 3,649E-05 4,691E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,734E-05 5,783E-03 ! establishment of tissue polarity GO:0007164 8 7 1,000 4,734E-05 5,507E-03 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 1,000 4,734E-05 5,257E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 4,804E-05 5,103E-03 ! positive regulation of protein transport GO:0051222 80 46 2,000 4,804E-05 4,89E-03 ! ER overload response GO:0006983 13 8 1,000 6,306E-05 6,162E-03 ! blastocyst growth GO:0001832 19 8 1,000 6,306E-05 5,925E-03 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 2,000 6,949E-05 6,287E-03 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 8,1E-05 7,067E-03 ! RNA elongation GO:0006354 90 56 2,000 8,679E-05 7,311E-03 ! regulation of intracellular transport GO:0032386 108 57 2,000 9,151E-05 7,452E-03 ! midbrain development GO:0030901 14 10 1,000 1,012E-04 7,971E-03 ! nucleosome positioning GO:0016584 15 11 1,000 1,235E-04 9,429E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 1,417E-04 0,01049276 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,481E-04 0,01063902 ! chromatin silencing GO:0006342 29 13 1,000 1,748E-04 0,01220225 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 1,761E-04 0,0119492 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 1,000 2,038E-04 0,01345332 GO:0046579|positive regulation of Ras protein signal transduction, ! activation of protein kinase activity GO:0032147 170 80 2,000 2,507E-04 0,01611649 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 2,000 2,6E-04 0,01628973 ! embryonic hindlimb morphogenesis GO:0035116 36 16 1,000 2,682E-04 0,01637814 ! stem cell development GO:0048864 46 16 1,000 2,682E-04 0,01597867 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 2,682E-04 0,01559823 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 1,000 3,036E-04 0,01725006 ! regulation of protein transport GO:0051223 165 87 2,000 3,21E-04 0,01782239 GO:0070201|regulation of establishment of protein localization, ! epidermis morphogenesis GO:0048730 43 18 1,000 3,412E-04 0,01852575 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 4,229E-04 0,0224619 ! regulation of protein localization GO:0032880 188 97 2,000 4,417E-04 0,02296123 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 4,67E-04 0,02376872 ! hindlimb morphogenesis GO:0035137 47 22 1,000 5,132E-04 0,02558708 ! stem cell differentiation GO:0048863 57 22 1,000 5,132E-04 0,02507533 ! peptidyl-serine modification GO:0018209 50 22 1,000 5,132E-04 0,02458366 ! protein amino acid alkylation GO:0008213 59 26 1,000 7,192E-04 0,03379039 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 7,192E-04 0,03315284 ! osteoblast differentiation GO:0001649 63 26 1,000 7,192E-04 0,0325389 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 7,192E-04 0,03194728 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 7,192E-04 0,03137679 ! blastocyst development GO:0001824 50 26 1,000 7,192E-04 0,03082632 ! embryonic pattern specification GO:0009880 49 27 1,000 7,76E-04 0,03268659 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 8,959E-04 0,03709531 ! mesoderm formation GO:0001707 73 32 1,000 1,091E-03 0,04443321 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 1,091E-03 0,04370479 ! gene silencing GO:0016458 71 32 1,000 1,091E-03 0,04299988 ! glial cell differentiation GO:0010001 67 34 1,000 1,232E-03 0,04776993 ! formation of primary germ layer GO:0001704 76 34 1,000 1,232E-03 0,04702352 ! mesoderm morphogenesis GO:0048332 80 35 1,000 1,305E-03 0,04905841 ! glycogen metabolic process GO:0005977 63 38 1,000 1,538E-03 0,0569186 ! glucan metabolic process GO:0044042 64 39 1,000 1,619E-03 0,05904239 GO:0006073|cellular glucan metabolic process, ! gliogenesis GO:0042063 91 41 1,000 1,788E-03 0,06425118 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 1,876E-03 0,06642141 ! epithelial cell differentiation GO:0030855 83 43 1,000 1,966E-03 0,06859961 ! energy reserve metabolic process GO:0006112 76 44 1,000 2,057E-03 0,07078524 ! keratinocyte differentiation GO:0030216 81 45 1,000 2,151E-03 0,07297778 ! biopolymer methylation GO:0043414 91 45 1,000 2,151E-03 0,07197808 ! developmental growth GO:0048589 88 45 1,000 2,151E-03 0,0710054 ! cell growth GO:0016049 90 46 1,000 2,246E-03 0,07317202 ! methylation GO:0032259 97 48 1,000 2,443E-03 0,07854485 ! protein homooligomerization GO:0051260 84 49 1,000 2,545E-03 0,08074525 ! regulation of ossification GO:0030278 123 50 1,000 2,648E-03 0,08295071 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 2,648E-03 0,0819007 ! epidermal cell differentiation GO:0009913 87 50 1,000 2,648E-03 0,08087694 ! Notch signaling pathway GO:0007219 111 52 1,000 2,861E-03 0,0862966 ! chromatin remodeling GO:0006338 122 53 1,000 2,971E-03 0,08850115 ! covalent chromatin modification GO:0016569 115 54 1,000 3,082E-03 0,09070964 ! regulation of bone remodeling GO:0046850 143 57 1,000 3,427E-03 0,09967379 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 3,546E-03 0,10192011 ! gastrulation GO:0007369 122 58 1,000 3,546E-03 0,10073499 ! regulation of tissue remodeling GO:0034103 146 58 1,000 3,546E-03 0,09957712 ! mesoderm development GO:0007498 128 63 1,000 4,169E-03 0,11574947 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 4,702E-03 0,12906658 GO:0035113|embryonic appendage morphogenesis, ! appendage morphogenesis GO:0035107 150 72 1,000 5,409E-03 0,14683476 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 151 73 1,000 5,556E-03 0,14916733 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 5,705E-03 0,15149761 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 6,163E-03 0,16188197 ! protein oligomerization GO:0051259 149 79 1,000 6,476E-03 0,16831774 ! regulation of peptidase activity GO:0052547 150 82 1,000 6,961E-03 0,17899877 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 7,574E-03 0,19273228 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 7,574E-03 0,19074535 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 7,574E-03 0,18879897 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 7,574E-03 0,18689191 ! positive regulation of helicase activity GO:0051096 12 5 0,000 7,574E-03 0,18502299 ! neuron fate determination GO:0048664 7 5 0,000 7,574E-03 0,18319108 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,574E-03 0,18139509 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 7,574E-03 0,17963397 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 7,574E-03 0,17790672 ! polyol transport GO:0015791 12 5 0,000 7,574E-03 0,17621237 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 7,574E-03 0,17454999 ! response to superoxide GO:0000303 10 5 0,000 7,574E-03 0,17291868 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,574E-03 0,17131758 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 7,574E-03 0,16974586 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 7,574E-03 0,16820272 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 7,574E-03 0,16668738 ! female meiosis GO:0007143 10 5 0,000 7,574E-03 0,1651991 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 7,574E-03 0,16373716 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 7,574E-03 0,16230087 ! hypothalamus development GO:0021854 9 5 0,000 7,574E-03 0,16088956 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 7,574E-03 0,15950258 ! cobalt ion transport GO:0006824 11 5 0,000 7,574E-03 0,15813931 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 7,574E-03 0,15679914 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 7,574E-03 0,15548151 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 7,574E-03 0,15418583 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 7,574E-03 0,15291156 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 7,574E-03 0,15165819 ! embryonic camera-type eye development GO:0031076 12 5 0,000 7,574E-03 0,1504252 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 7,574E-03 0,14921209 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,574E-03 0,14801839 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 7,574E-03 0,14684364 ! transposition GO:0032196 9 5 0,000 7,574E-03 0,14568739 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 7,574E-03 0,14454921 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 7,574E-03 0,14342868 ! negative chemotaxis GO:0050919 16 5 0,000 7,574E-03 0,14232538 ! positive regulation of histone modification GO:0031058 6 5 0,000 7,574E-03 0,14123892 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 7,574E-03 0,14016893 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 7,574E-03 0,13911503 ! behavioral response to pain GO:0048266 10 5 0,000 7,574E-03 0,13807686 ! clathrin coat assembly GO:0048268 15 5 0,000 7,574E-03 0,13705407 ! Notch receptor processing GO:0007220 11 5 0,000 7,574E-03 0,13604632 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,574E-03 0,13505328 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 7,574E-03 0,13407463 ! micturition GO:0060073 9 5 0,000 7,574E-03 0,13311007 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 7,574E-03 0,13215928 ! copulation GO:0007620 9 5 0,000 7,574E-03 0,13122198 ! bioluminescence GO:0008218 9 5 0,000 7,574E-03 0,13029788 ! spermidine metabolic process GO:0008216 7 5 0,000 7,574E-03 0,12938671 ! regulation of potassium ion transport GO:0043266 10 5 0,000 7,574E-03 0,12848819 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 7,574E-03 0,12760206 ! apoptotic cell clearance GO:0043277 23 5 0,000 7,574E-03 0,12672808 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 7,574E-03 0,12586598 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 7,574E-03 0,12501553 ! lipoprotein particle clearance GO:0034381 10 5 0,000 7,574E-03 0,1241765 ! grooming behavior GO:0007625 6 5 0,000 7,574E-03 0,12334866 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 7,574E-03 0,12253178 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 7,574E-03 0,12172565 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 7,574E-03 0,12093006 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,574E-03 0,1201448 ! response to protozoan GO:0001562 13 5 0,000 7,574E-03 0,11936967 ! positive regulation of glycolysis GO:0045821 13 5 0,000 7,574E-03 0,11860448 ! lymph vessel development GO:0001945 10 5 0,000 7,574E-03 0,11784904 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 7,574E-03 0,11710316 ! endochondral ossification GO:0001958 17 5 0,000 7,574E-03 0,11636666 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 7,574E-03 0,11563937 ! single strand break repair GO:0000012 8 5 0,000 7,574E-03 0,11492111 ! parathyroid gland development GO:0060017 14 5 0,000 7,574E-03 0,11421172 ! anagen GO:0042640 7 5 0,000 7,574E-03 0,11351104 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 7,574E-03 0,1128189 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 7,574E-03 0,11213515 ! cytokine secretion GO:0050663 15 5 0,000 7,574E-03 0,11145963 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 7,574E-03 0,11079221 ! ceramide catabolic process GO:0046514 7 5 0,000 7,574E-03 0,11013273 ! skeletal myofibril assembly GO:0014866 12 5 0,000 7,574E-03 0,10948106 ! smooth muscle tissue development GO:0048745 32 5 0,000 7,574E-03 0,10883705 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 7,574E-03 0,10820058 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 7,574E-03 0,10757151 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 7,574E-03 0,10694971 ! cardiac muscle fiber development GO:0048739 12 5 0,000 7,574E-03 0,10633505 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 7,574E-03 0,10572742 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 7,574E-03 0,1051267 ! neutrophil mediated immunity GO:0002446 7 5 0,000 7,574E-03 0,10453276 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 7,574E-03 0,1039455 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 7,574E-03 0,1033648 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 7,574E-03 0,10279055 ! glycine biosynthetic process GO:0006545 7 5 0,000 7,574E-03 0,10222265 ! microvillus organization GO:0032528 8 5 0,000 7,574E-03 0,10166098 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 7,574E-03 0,10110546 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 7,574E-03 0,10055597 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 7,574E-03 0,10001243 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 7,574E-03 0,09947473 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 7,574E-03 0,09894278 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 7,574E-03 0,09841648 ! polyol catabolic process GO:0046174 9 5 0,000 7,574E-03 0,09789576 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 7,574E-03 0,09738052 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 7,574E-03 0,09687068 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 7,574E-03 0,09636614 ! muscle cell migration GO:0014812 8 5 0,000 7,574E-03 0,09586683 ! mitochondrial fission GO:0000266 8 5 0,000 7,574E-03 0,09537268 ! sister chromatid cohesion GO:0007062 15 5 0,000 7,574E-03 0,09488359 ! response to tumor necrosis factor GO:0034612 10 5 0,000 7,574E-03 0,09439949 ! mRNA transcription GO:0009299 10 5 0,000 7,574E-03 0,0939203 ! nerve growth factor processing GO:0032455 9 5 0,000 7,574E-03 0,09344596 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 7,574E-03 0,09297638 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 7,574E-03 0,0925115 ! anaerobic glycolysis GO:0019642 6 5 0,000 7,574E-03 0,09205124 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 7,574E-03 0,09159554 ! monocyte activation GO:0042117 10 5 0,000 7,574E-03 0,09114433 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 7,574E-03 0,09069754 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 7,574E-03 0,09025512 ! response to food GO:0032094 6 5 0,000 7,574E-03 0,08981699 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 7,574E-03 0,08938309 ! positive regulation of transporter activity GO:0032411 8 5 0,000 7,574E-03 0,08895336 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 7,574E-03 0,08852775 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,574E-03 0,08810619 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 7,574E-03 0,08768862 ! forebrain neuron development GO:0021884 13 5 0,000 7,574E-03 0,087275 ! lipoprotein catabolic process GO:0042159 11 5 0,000 7,574E-03 0,08686525 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 7,574E-03 0,08645934 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 7,574E-03 0,08605721 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 7,574E-03 0,08565879 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,574E-03 0,08526405 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 7,574E-03 0,08487293 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 7,574E-03 0,08448538 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 7,574E-03 0,08410136 ! lipid glycosylation GO:0030259 7 5 0,000 7,574E-03 0,08372081 ! nucleobase transport GO:0015851 6 5 0,000 7,574E-03 0,08334369 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,574E-03 0,08296995 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 7,574E-03 0,08259955 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 7,574E-03 0,08223244 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 7,574E-03 0,08186858 ! basic amino acid transport GO:0015802 12 5 0,000 7,574E-03 0,08150793 ! cellular glucose homeostasis GO:0001678 6 5 0,000 7,574E-03 0,08115043 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 7,574E-03 0,08079607 ! actin nucleation GO:0045010 11 5 0,000 7,574E-03 0,08044478 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,574E-03 0,08009653 ! depurination GO:0045007 5 5 0,000 7,574E-03 0,07975129 ! depyrimidination GO:0045008 10 5 0,000 7,574E-03 0,07940901 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 7,574E-03 0,07906965 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,574E-03 0,07873319 ! G2/M transition checkpoint GO:0031576 8 5 0,000 7,574E-03 0,07839957 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 7,574E-03 0,07806877 ! zinc ion homeostasis GO:0055069 9 5 0,000 7,574E-03 0,07774075 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 7,574E-03 0,07741548 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 7,574E-03 0,07709291 ! forebrain morphogenesis GO:0048853 13 5 0,000 7,574E-03 0,07677303 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 7,574E-03 0,07645578 ! activated T cell proliferation GO:0050798 16 5 0,000 7,574E-03 0,07614115 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 7,574E-03 0,07582909 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 7,574E-03 0,07551959 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 7,574E-03 0,0752126 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,574E-03 0,07490809 ! gamma-delta T cell activation GO:0046629 6 5 0,000 7,574E-03 0,07460604 ! response to arsenic GO:0046685 11 5 0,000 7,574E-03 0,07430642 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 7,574E-03 0,0740092 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 7,574E-03 0,07371434 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 7,574E-03 0,07342182 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 7,574E-03 0,07313162 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 7,574E-03 0,0728437 ! response to mercury ion GO:0046689 8 5 0,000 7,574E-03 0,07255804 ! response to cadmium ion GO:0046686 7 5 0,000 7,574E-03 0,07227461 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 7,574E-03 0,07199338 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 7,574E-03 0,07171434 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 7,574E-03 0,07143745 ! bile acid biosynthetic process GO:0006699 7 5 0,000 7,574E-03 0,07116269 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 7,574E-03 0,07089003 ! ganglioside catabolic process GO:0006689 12 5 0,000 7,574E-03 0,07061946 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 7,574E-03 0,07035095 ! decidualization GO:0046697 11 5 0,000 7,574E-03 0,07008447 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 7,574E-03 0,06982 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 7,574E-03 0,06955752 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 7,574E-03 0,069297 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 7,574E-03 0,06903843 ! embryonic cleavage GO:0040016 6 5 0,000 7,574E-03 0,06878178 ! peroxisome fission GO:0016559 5 5 0,000 7,574E-03 0,06852703 ! histone demethylation GO:0016577 13 5 0,000 7,574E-03 0,06827417 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 7,574E-03 0,06802316 ! mitotic recombination GO:0006312 9 5 0,000 7,574E-03 0,06777399 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 7,574E-03 0,06752664 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 7,574E-03 0,06728109 ! metaphase plate congression GO:0051310 7 5 0,000 7,574E-03 0,06703732 ! regulation of sterol transport GO:0032371 7 5 0,000 7,574E-03 0,0667953 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 7,574E-03 0,06655503 ! enteric nervous system development GO:0048484 8 5 0,000 7,574E-03 0,06631648 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 7,574E-03 0,06607964 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 7,574E-03 0,06584448 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 7,574E-03 0,06561099 ! muscle cell proliferation GO:0033002 12 5 0,000 7,574E-03 0,06537915 ! skeletal muscle regeneration GO:0043403 8 5 0,000 7,574E-03 0,06514894 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 7,574E-03 0,06492035 ! B cell homeostasis GO:0001782 13 5 0,000 7,574E-03 0,06469335 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 7,574E-03 0,06446794 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 7,574E-03 0,06424409 ! metaphase GO:0051323 11 5 0,000 7,574E-03 0,0640218 ! melatonin biosynthetic process GO:0030187 7 5 0,000 7,574E-03 0,06380103 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 7,574E-03 0,06358178 ! cellular response to nutrient GO:0031670 8 5 0,000 7,574E-03 0,06336404 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 7,574E-03 0,06314778 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 7,574E-03 0,06293299 ! regulation of hair follicle development GO:0051797 10 5 0,000 7,574E-03 0,06271966 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 7,574E-03 0,06250777 ! response to redox state GO:0051775 6 5 0,000 7,574E-03 0,0622973 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 7,574E-03 0,06208825 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 7,574E-03 0,0618806 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 7,574E-03 0,06167433 ! brown fat cell differentiation GO:0050873 7 5 0,000 7,574E-03 0,06146943 ! regulation of telomerase activity GO:0051972 7 5 0,000 7,574E-03 0,06126589 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,574E-03 0,06106369 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 7,574E-03 0,06086283 ! porphyrin catabolic process GO:0006787 12 5 0,000 7,574E-03 0,06066328 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 7,574E-03 0,06046503 ! striatum development GO:0021756 14 5 0,000 7,574E-03 0,06026808 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 7,574E-03 0,0600724 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 7,574E-03 0,05987799 ! glial cell migration GO:0008347 10 5 0,000 7,574E-03 0,05968484 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 7,574E-03 0,05949292 ! neural plate morphogenesis GO:0001839 7 5 0,000 7,574E-03 0,05930224 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 7,574E-03 0,05911278 ! somatic stem cell maintenance GO:0035019 15 5 0,000 7,574E-03 0,05892452 ! T cell activation during immune response GO:0002286 9 5 0,000 7,574E-03 0,05873746 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 7,574E-03 0,05855158 ! negative regulation of lipase activity GO:0060192 8 5 0,000 7,574E-03 0,05836687 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 7,574E-03 0,05818333 ! neuroprotection GO:0043526 8 5 0,000 7,574E-03 0,05800094 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 7,574E-03 0,05781968 ! regulation of sensory perception GO:0051931 8 5 0,000 7,574E-03 0,05763956 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 7,574E-03 0,05746056 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 7,574E-03 0,05728266 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 7,574E-03 0,05710586 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 7,574E-03 0,05693015 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 7,574E-03 0,05675552 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 7,574E-03 0,05658195 ! sequestering of calcium ion GO:0051208 7 5 0,000 7,574E-03 0,05640945 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 7,574E-03 0,05623799 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 7,574E-03 0,05606757 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 7,574E-03 0,05589818 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 7,574E-03 0,05572982 ! spindle assembly GO:0051225 6 5 0,000 7,574E-03 0,05556246 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 7,574E-03 0,05539611 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 7,574E-03 0,05523074 ! protein palmitoylation GO:0018345 12 5 0,000 7,574E-03 0,05506637 ! drug metabolic process GO:0017144 7 5 0,000 7,574E-03 0,05490296 ! stem cell division GO:0017145 11 5 0,000 7,574E-03 0,05474053 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 7,574E-03 0,05457905 ! organ regeneration GO:0031100 7 5 0,000 7,574E-03 0,05441853 ! carnitine metabolic process GO:0009437 8 5 0,000 7,574E-03 0,05425894 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 7,574E-03 0,05410029 ! nucleosome assembly GO:0006334 126 87 1,000 7,803E-03 0,05557726 ! chromatin assembly GO:0031497 128 88 1,000 7,977E-03 0,05664961 ! one-carbon metabolic process GO:0006730 167 88 1,000 7,977E-03 0,05648541 ! ossification GO:0001503 205 91 1,000 8,509E-03 0,06007602 ! bone development GO:0060348 206 92 1,000 8,689E-03 0,06117488 ! protein-DNA complex assembly GO:0065004 134 92 1,000 8,689E-03 0,06099909 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 9,082E-03 0,06357083 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 9,082E-03 0,0633892 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 9,082E-03 0,0632086 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 9,082E-03 0,06302903 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 9,082E-03 0,06285048 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 9,082E-03 0,06267294 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 9,082E-03 0,0624964 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 9,082E-03 0,06232084 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 9,082E-03 0,06214628 ! response to oxygen radical GO:0000305 11 6 0,000 9,082E-03 0,06197268 ! positive regulation of axon extension GO:0045773 13 6 0,000 9,082E-03 0,06180006 ! myoblast cell fate commitment GO:0048625 18 6 0,000 9,082E-03 0,06162839 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 9,082E-03 0,06145767 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 9,082E-03 0,0612879 ! regulation of interferon-beta production GO:0032648 8 6 0,000 9,082E-03 0,06111906 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 9,082E-03 0,06095115 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 9,082E-03 0,06078417 ! forebrain regionalization GO:0021871 9 6 0,000 9,082E-03 0,06061809 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 9,082E-03 0,06045292 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 9,082E-03 0,06028864 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 9,082E-03 0,06012526 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 9,082E-03 0,05996276 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 9,082E-03 0,05980113 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 9,082E-03 0,05964038 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 9,082E-03 0,05948048 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 9,082E-03 0,05932144 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 9,082E-03 0,05916325 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 9,082E-03 0,05900591 ! malate metabolic process GO:0006108 13 6 0,000 9,082E-03 0,05884939 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 9,082E-03 0,0586937 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 9,082E-03 0,05853884 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 9,082E-03 0,05838479 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 9,082E-03 0,05823155 ! protein refolding GO:0042026 15 6 0,000 9,082E-03 0,05807911 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 9,082E-03 0,05792747 ! opsonization GO:0008228 8 6 0,000 9,082E-03 0,05777662 ! mating behavior GO:0007617 7 6 0,000 9,082E-03 0,05762655 ! erythrocyte maturation GO:0043249 8 6 0,000 9,082E-03 0,05747725 ! embryonic hemopoiesis GO:0035162 16 6 0,000 9,082E-03 0,05732873 ! protein amino acid dealkylation GO:0008214 15 6 0,000 9,082E-03 0,05718098 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 9,082E-03 0,05703399 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 9,082E-03 0,05688774 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 9,082E-03 0,05674225 ! response to interferon-gamma GO:0034341 16 6 0,000 9,082E-03 0,0565975 ! toxin metabolic process GO:0009404 11 6 0,000 9,082E-03 0,05645349 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 9,082E-03 0,0563102 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 9,082E-03 0,05616765 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 9,082E-03 0,05602581 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 9,082E-03 0,05588469 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 9,082E-03 0,05574427 ! cGMP-mediated signaling GO:0019934 14 6 0,000 9,082E-03 0,05560456 ! dorsal spinal cord development GO:0021516 10 6 0,000 9,082E-03 0,05546555 ! activation of MAPKKK activity GO:0000185 12 6 0,000 9,082E-03 0,05532723 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 9,082E-03 0,0551896 ! thymic T cell selection GO:0045061 16 6 0,000 9,082E-03 0,05505266 ! sphingoid catabolic process GO:0046521 8 6 0,000 9,082E-03 0,05491639 ! protein lipoylation GO:0009249 10 6 0,000 9,082E-03 0,05478079 ! transepithelial chloride transport GO:0030321 12 6 0,000 9,082E-03 0,05464586 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 9,082E-03 0,0545116 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 9,082E-03 0,05437799 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 9,082E-03 0,05424504 ! glutamate catabolic process GO:0006538 12 6 0,000 9,082E-03 0,05411273 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 9,082E-03 0,05398107 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 9,082E-03 0,05385005 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 9,082E-03 0,05371966 ! hyperosmotic response GO:0006972 10 6 0,000 9,082E-03 0,0535899 ! L-serine biosynthetic process GO:0006564 7 6 0,000 9,082E-03 0,05346077 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 9,082E-03 0,05333226 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 9,082E-03 0,05320437 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 9,082E-03 0,05307708 ! urea metabolic process GO:0019627 7 6 0,000 9,082E-03 0,05295041 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 9,082E-03 0,05282433 ! neutrophil activation GO:0042119 7 6 0,000 9,082E-03 0,05269886 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 9,082E-03 0,05257398 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 9,082E-03 0,05244969 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 9,082E-03 0,05232599 ! paraxial mesoderm development GO:0048339 16 6 0,000 9,082E-03 0,05220287 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 9,082E-03 0,05208033 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 9,082E-03 0,05195836 ! neuron apoptosis GO:0051402 15 6 0,000 9,082E-03 0,05183696 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 9,082E-03 0,05171613 ! T cell mediated immunity GO:0002456 17 6 0,000 9,082E-03 0,05159586 ! negative regulation of platelet activation GO:0010544 9 6 0,000 9,082E-03 0,05147615 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 9,082E-03 0,05135699 ! carnitine transport GO:0015879 10 6 0,000 9,082E-03 0,05123838 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,082E-03 0,05112032 ! positive regulation of exocytosis GO:0045921 11 6 0,000 9,082E-03 0,05100281 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 9,082E-03 0,05088583 ! early endosome to late endosome transport GO:0045022 16 6 0,000 9,082E-03 0,05076938 ! 5S class rRNA transcription GO:0042791 13 6 0,000 9,082E-03 0,05065347 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 9,082E-03 0,05053809 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 9,082E-03 0,05042323 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 9,082E-03 0,05030889 ! sodium ion homeostasis GO:0055078 12 6 0,000 9,082E-03 0,05019507 ! establishment of spindle localization GO:0051293 16 6 0,000 9,082E-03 0,05008176 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 9,082E-03 0,04996896 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 9,082E-03 0,04985667 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 9,082E-03 0,04974489 ! response to UV-C GO:0010225 14 6 0,000 9,082E-03 0,0496336 ! astrocyte development GO:0014002 16 6 0,000 9,082E-03 0,04952281 ! protein targeting to lysosome GO:0006622 12 6 0,000 9,082E-03 0,04941252 ! purine base biosynthetic process GO:0009113 17 6 0,000 9,082E-03 0,04930271 ! interaction with symbiont GO:0051702 14 6 0,000 9,082E-03 0,04919339 ! regulation of dendrite development GO:0050773 16 6 0,000 9,082E-03 0,04908456 ! peptidyl-arginine modification GO:0018195 13 6 0,000 9,082E-03 0,0489762 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 9,082E-03 0,04886833 ! response to copper ion GO:0046688 10 6 0,000 9,082E-03 0,04876092 ! response to exogenous dsRNA GO:0043330 13 6 0,000 9,082E-03 0,04865399 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 9,082E-03 0,04854753 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,082E-03 0,04844153 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 9,082E-03 0,04833599 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 9,082E-03 0,04823091 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 9,082E-03 0,04812629 ! regulation of dopamine secretion GO:0014059 14 6 0,000 9,082E-03 0,04802212 ! nucleoside catabolic process GO:0009164 10 6 0,000 9,082E-03 0,0479184 ! hair follicle maturation GO:0048820 8 6 0,000 9,082E-03 0,04781513 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 9,082E-03 0,0477123 ! Schwann cell development GO:0014044 15 6 0,000 9,082E-03 0,04760991 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 9,082E-03 0,04750797 ! response to pheromone GO:0019236 6 6 0,000 9,082E-03 0,04740645 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 9,082E-03 0,04730537 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 9,082E-03 0,04720472 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 9,082E-03 0,0471045 ! base conversion or substitution editing GO:0016553 6 6 0,000 9,082E-03 0,0470047 ! subpallium development GO:0021544 15 6 0,000 9,082E-03 0,04690533 ! neural tube patterning GO:0021532 8 6 0,000 9,082E-03 0,04680637 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 9,082E-03 0,04670783 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 9,082E-03 0,04660971 ! maintenance of organ identity GO:0048496 9 6 0,000 9,082E-03 0,04651199 ! G2 phase GO:0051319 16 6 0,000 9,082E-03 0,04641469 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 9,082E-03 0,04631779 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 9,082E-03 0,04622129 ! oxygen homeostasis GO:0032364 10 6 0,000 9,082E-03 0,0461252 ! establishment of planar polarity GO:0001736 7 6 0,000 9,082E-03 0,0460295 ! regulation of mast cell activation GO:0033003 13 6 0,000 9,082E-03 0,0459342 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 9,082E-03 0,0458393 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 9,082E-03 0,04574478 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 9,082E-03 0,04565066 ! receptor internalization GO:0031623 11 6 0,000 9,082E-03 0,04555692 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 9,082E-03 0,04546357 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 9,082E-03 0,04537059 ! neutrophil homeostasis GO:0001780 11 6 0,000 9,082E-03 0,045278 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,082E-03 0,04518578 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 9,082E-03 0,04509394 ! protein deubiquitination GO:0016579 16 6 0,000 9,082E-03 0,04500248 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 9,082E-03 0,04491138 ! protein destabilization GO:0031648 9 6 0,000 9,082E-03 0,04482065 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 9,082E-03 0,04473028 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 9,082E-03 0,04464028 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 9,082E-03 0,04455064 ! regulation of viral transcription GO:0046782 11 6 0,000 9,082E-03 0,04446136 ! progesterone metabolic process GO:0042448 12 6 0,000 9,082E-03 0,04437244 ! negative regulation of axon extension GO:0030517 24 6 0,000 9,082E-03 0,04428387 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 9,082E-03 0,04419566 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 9,082E-03 0,04410779 ! triglyceride catabolic process GO:0019433 10 6 0,000 9,082E-03 0,04402028 ! determination of adult lifespan GO:0008340 17 6 0,000 9,082E-03 0,04393311 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 9,082E-03 0,04384629 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 9,082E-03 0,0437598 ! neural plate development GO:0001840 9 6 0,000 9,082E-03 0,04367366 ! catecholamine transport GO:0051937 9 6 0,000 9,082E-03 0,04358786 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 9,082E-03 0,04350239 ! sensory cilium assembly GO:0035058 10 6 0,000 9,082E-03 0,04341726 ! organ or tissue specific immune response GO:0002251 8 6 0,000 9,082E-03 0,04333246 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 9,082E-03 0,04324799 ! maternal placenta development GO:0001893 12 6 0,000 9,082E-03 0,04316385 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 9,082E-03 0,04308004 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 9,082E-03 0,04299655 ! negative regulation of B cell activation GO:0050869 14 6 0,000 9,082E-03 0,04291339 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 9,082E-03 0,04283054 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 9,082E-03 0,04274802 ! positive regulation of coagulation GO:0050820 13 6 0,000 9,082E-03 0,04266581 ! cellular anion homeostasis GO:0030002 11 6 0,000 9,082E-03 0,04258392 GO:0055081|anion homeostasis, ! nucleosome organization GO:0034728 143 95 1,000 9,241E-03 0,04325087 ! forebrain development GO:0030900 210 98 1,000 9,809E-03 0,04581955 ! tRNA transcription GO:0009304 17 7 0,000 0,01058725 0,04936001 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01058725 0,049266 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01058725 0,04917233 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01058725 0,04907903 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01058725 0,04898607 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01058725 0,04889347 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01058725 0,04880122 ! sleep GO:0030431 16 7 0,000 0,01058725 0,04870932 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01058725 0,04861776 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01058725 0,04852654 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01058725 0,04843567 ! prostate gland development GO:0030850 14 7 0,000 0,01058725 0,04834514 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01058725 0,04825494 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01058725 0,04816508 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01058725 0,04807555 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01058725 0,04798636 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01058725 0,0478975 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01058725 0,04780896 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01058725 0,04772075 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01058725 0,04763287 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01058725 0,04754531 ! glycolipid transport GO:0046836 11 7 0,000 0,01058725 0,04745807 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01058725 0,04737115 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,01058725 0,04728455 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01058725 0,04719826 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01058725 0,04711229 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01058725 0,04702663 ! mRNA stabilization GO:0048255 18 7 0,000 0,01058725 0,04694128 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01058725 0,04685625 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01058725 0,04677151 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01058725 0,04668709 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01058725 0,04660297 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01058725 0,04651915 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01058725 0,04643563 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01058725 0,04635241 ! lipoprotein transport GO:0042953 14 7 0,000 0,01058725 0,04626949 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01058725 0,04618687 ! rhythmic behavior GO:0007622 17 7 0,000 0,01058725 0,04610454 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01058725 0,0460225 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01058725 0,04594076 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01058725 0,0458593 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01058725 0,04577814 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01058725 0,04569726 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01058725 0,04561666 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01058725 0,04553635 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01058725 0,04545632 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01058725 0,04537657 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01058725 0,04529711 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01058725 0,04521792 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01058725 0,045139 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01058725 0,04506036 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01058725 0,044982 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01058725 0,0449039 ! spinal cord patterning GO:0021511 14 7 0,000 0,01058725 0,04482608 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01058725 0,04474853 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01058725 0,04467124 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01058725 0,04459422 ! adrenal gland development GO:0030325 17 7 0,000 0,01058725 0,04451747 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01058725 0,04444098 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01058725 0,04436475 ! ovulation GO:0030728 10 7 0,000 0,01058725 0,04428878 ! adenohypophysis development GO:0021984 11 7 0,000 0,01058725 0,04421307 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01058725 0,04413762 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01058725 0,04406243 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01058725 0,0439875 ! microtubule nucleation GO:0007020 21 7 0,000 0,01058725 0,04391281 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01058725 0,04383839 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01058725 0,04376421 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01058725 0,04369028 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01058725 0,04361661 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01058725 0,04354318 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01058725 0,04347 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01058725 0,04339706 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01058725 0,04332437 ! galactose metabolic process GO:0006012 13 7 0,000 0,01058725 0,04325192 ! vesicle fusion GO:0006906 20 7 0,000 0,01058725 0,04317971 ! response to dietary excess GO:0002021 8 7 0,000 0,01058725 0,04310775 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01058725 0,04303602 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01058725 0,04296453 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01058725 0,04289328 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01058725 0,04282226 ! organ growth GO:0035265 15 7 0,000 0,01058725 0,04275148 ! nucleoside transport GO:0015858 11 7 0,000 0,01058725 0,04268094 ! nucleoside salvage GO:0043174 11 7 0,000 0,01058725 0,04261062 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01058725 0,04254054 ! male sex determination GO:0030238 15 7 0,000 0,01058725 0,04247069 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01058725 0,04240106 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01058725 0,04233167 ! parturition GO:0007567 16 7 0,000 0,01058725 0,0422625 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01058725 0,04219355 ! rRNA modification GO:0000154 14 7 0,000 0,01058725 0,04212483 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01058725 0,04205634 ! spindle checkpoint GO:0031577 16 7 0,000 0,01058725 0,04198806 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01058725 0,04192001 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01058725 0,04185218 ! monocyte differentiation GO:0030224 16 7 0,000 0,01058725 0,04178457 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01058725 0,04171717 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01058725 0,04165 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01058725 0,04158303 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01058725 0,04151629 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01058725 0,04144976 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01058725 0,04138344 ! fibrinolysis GO:0042730 11 7 0,000 0,01058725 0,04131733 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01058725 0,04125143 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01058725 0,04118574 ! eating behavior GO:0042755 8 7 0,000 0,01058725 0,04112027 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01058725 0,041055 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01058725 0,04098993 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01058725 0,04092508 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01058725 0,04086042 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01058725 0,04079597 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01058725 0,04073173 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01058725 0,04066768 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01058725 0,04060384 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01058725 0,0405402 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01058725 0,04047676 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01058725 0,04041351 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01058725 0,04035046 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01058725 0,04028761 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01058725 0,04022496 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01058725 0,0401625 ! histone ubiquitination GO:0016574 9 7 0,000 0,01058725 0,04010023 ! regulation of meiosis GO:0040020 12 7 0,000 0,01058725 0,04003815 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01058725 0,03997627 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01058725 0,03991458 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01058725 0,03985308 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01058725 0,03979177 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01058725 0,03973064 ! transcription termination GO:0006353 14 7 0,000 0,01058725 0,0396697 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01058725 0,03960895 ! anaphase GO:0051322 18 7 0,000 0,01058725 0,03954839 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01058725 0,03948801 ! axonal fasciculation GO:0007413 19 7 0,000 0,01058725 0,03942782 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01058725 0,0393678 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01058725 0,03930797 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01058725 0,03924833 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01058725 0,03918886 ! diuresis GO:0030146 12 7 0,000 0,01058725 0,03912957 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01058725 0,03907046 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01058725 0,03901153 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01058725 0,03895278 ! antibiotic transport GO:0042891 9 7 0,000 0,01058725 0,03889421 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01058725 0,03883581 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01058725 0,03877758 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01058725 0,03871953 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01058725 0,03866166 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01058725 0,03860395 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01058725 0,03854642 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01058725 0,03848906 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01058725 0,03843187 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01058725 0,03837485 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01058725 0,038318 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01058725 0,03826131 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01058725 0,0382048 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01058725 0,03814845 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01058725 0,03809226 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01058725 0,03803625 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01058725 0,03798039 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01058725 0,0379247 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01058725 0,03786918 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01058725 0,03781381 ! muscle adaptation GO:0043500 13 7 0,000 0,01058725 0,03775861 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01058725 0,03770357 ! retina homeostasis GO:0001895 12 7 0,000 0,01058725 0,03764869 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01058725 0,03759396 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01058725 0,0375394 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01058725 0,037485 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01058725 0,03743075 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,0120907 0,04268438 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,0120907 0,04262278 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,0120907 0,04256137 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,0120907 0,04250013 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,0120907 0,04243906 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,0120907 0,04237818 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0120907 0,04231746 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0120907 0,04225692 ! male meiosis GO:0007140 9 8 0,000 0,0120907 0,04219656 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,0120907 0,04213636 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,0120907 0,04207634 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,0120907 0,04201648 ! meiotic prophase I GO:0007128 14 8 0,000 0,0120907 0,0419568 ! response to zinc ion GO:0010043 12 8 0,000 0,0120907 0,04189729 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,0120907 0,04183794 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0120907 0,04177877 ! oligopeptide transport GO:0006857 16 8 0,000 0,0120907 0,04171976 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,0120907 0,04166091 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,0120907 0,04160224 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,0120907 0,04154373 ! signal peptide processing GO:0006465 12 8 0,000 0,0120907 0,04148538 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,0120907 0,04142719 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,0120907 0,04136917 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0120907 0,04131131 ! succinate metabolic process GO:0006105 17 8 0,000 0,0120907 0,04125362 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,0120907 0,04119608 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,0120907 0,0411387 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0120907 0,04108149 ! estrogen metabolic process GO:0008210 17 8 0,000 0,0120907 0,04102443 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,0120907 0,04096753 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0120907 0,04091079 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,0120907 0,0408542 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0120907 0,04079777 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0120907 0,0407415 ! reflex GO:0060004 17 8 0,000 0,0120907 0,04068538 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0120907 0,04062942 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,0120907 0,04057361 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,0120907 0,04051795 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0120907 0,04046245 ! pigment granule organization GO:0048753 17 8 0,000 0,0120907 0,0404071 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0120907 0,0403519 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,0120907 0,04029685 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,0120907 0,04024195 ! astrocyte differentiation GO:0048708 19 8 0,000 0,0120907 0,0401872 ! histidine catabolic process GO:0006548 10 8 0,000 0,0120907 0,04013259 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0120907 0,04007814 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,0120907 0,04002383 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,0120907 0,03996967 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,0120907 0,03991566 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,0120907 0,03986179 ! melanin metabolic process GO:0006582 17 8 0,000 0,0120907 0,03980807 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,0120907 0,03975449 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,0120907 0,03970106 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,0120907 0,03964777 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0120907 0,03959462 ! macrophage activation GO:0042116 13 8 0,000 0,0120907 0,03954162 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0120907 0,03948875 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0120907 0,03943603 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,0120907 0,03938345 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0120907 0,03933101 ! purine salvage GO:0043101 12 8 0,000 0,0120907 0,03927871 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,0120907 0,03922655 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0120907 0,03917452 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,0120907 0,03912263 ! osteoblast development GO:0002076 17 8 0,000 0,0120907 0,03907088 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,0120907 0,03901927 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,0120907 0,03896779 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,0120907 0,03891645 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,0120907 0,03886525 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0120907 0,03881418 ! response to UV-B GO:0010224 17 8 0,000 0,0120907 0,03876324 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,0120907 0,03871244 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0120907 0,03866177 ! intermediate filament organization GO:0045109 12 8 0,000 0,0120907 0,03861123 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,0120907 0,03856082 ! cellular extravasation GO:0045123 13 8 0,000 0,0120907 0,03851055 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,0120907 0,0384604 ! response to antibiotic GO:0046677 11 8 0,000 0,0120907 0,03841039 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,0120907 0,0383605 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,0120907 0,03831075 ! DNA topological change GO:0006265 12 8 0,000 0,0120907 0,03826113 ! response to tropane GO:0014073 15 8 0,000 0,0120907 0,03821163 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,0120907 0,03816226 ! melanosome transport GO:0032402 13 8 0,000 0,0120907 0,03811302 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,0120907 0,0380639 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,0120907 0,03801491 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0120907 0,03796605 ! mast cell activation GO:0045576 14 8 0,000 0,0120907 0,03791732 ! multicellular organismal aging GO:0010259 20 8 0,000 0,0120907 0,0378687 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,0120907 0,03782022 ! gas homeostasis GO:0033483 14 8 0,000 0,0120907 0,03777185 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,0120907 0,03772361 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,0120907 0,0376755 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,0120907 0,0376275 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0120907 0,03757963 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0120907 0,03753188 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,0120907 0,03748425 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0120907 0,03743674 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,0120907 0,03738935 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,0120907 0,03734208 ! intracellular lipid transport GO:0032365 16 8 0,000 0,0120907 0,03729494 ! response to tumor cell GO:0002347 16 8 0,000 0,0120907 0,0372479 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0120907 0,03720099 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,0120907 0,0371542 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,0120907 0,03710752 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,0120907 0,03706096 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0120907 0,03701452 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,0120907 0,0369682 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,0120907 0,03692199 ! hormone catabolic process GO:0042447 17 8 0,000 0,0120907 0,03687589 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,0120907 0,03682991 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,0120907 0,03678405 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,0120907 0,03673829 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,0120907 0,03669266 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0120907 0,03664713 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,0120907 0,03660172 ! adult feeding behavior GO:0008343 10 8 0,000 0,0120907 0,03655642 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,0120907 0,03651123 ! ATP catabolic process GO:0006200 11 8 0,000 0,0120907 0,03646616 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0120907 0,03642119 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0120907 0,03637634 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,0120907 0,0363316 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0120907 0,03628696 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,0120907 0,03624244 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,0120907 0,03619803 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,0120907 0,03615372 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,0120907 0,03610952 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,0120907 0,03606543 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,0120907 0,03602145 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0120907 0,03597757 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,0120907 0,03593381 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,0120907 0,03589014 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0120907 0,03584659 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,0120907 0,03580314 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,0120907 0,03575979 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0120907 0,03571655 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,0120907 0,03567342 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,0120907 0,03563038 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,0120907 0,03558746 ! axon extension GO:0048675 16 9 0,000 0,01359192 0,03995794 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01359192 0,03990992 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01359192 0,03986201 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01359192 0,03981421 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01359192 0,03976653 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01359192 0,03971896 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01359192 0,03967151 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01359192 0,03962417 ! reproductive behavior GO:0019098 22 9 0,000 0,01359192 0,03957694 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01359192 0,03952982 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01359192 0,03948282 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01359192 0,03943593 ! UTP metabolic process GO:0046051 10 9 0,000 0,01359192 0,03938915 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01359192 0,03934248 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01359192 0,03929592 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01359192 0,03924947 ! artery development GO:0060840 25 9 0,000 0,01359192 0,03920313 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01359192 0,0391569 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01359192 0,03911078 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01359192 0,03906477 ! equilibrioception GO:0050957 20 9 0,000 0,01359192 0,03901886 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01359192 0,03897307 ! chemosensory behavior GO:0007635 21 9 0,000 0,01359192 0,03892738 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01359192 0,03888179 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01359192 0,03883632 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01359192 0,03879095 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01359192 0,03874568 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01359192 0,03870053 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01359192 0,03865547 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01359192 0,03861053 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01359192 0,03856568 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01359192 0,03852094 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01359192 0,03847631 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01359192 0,03843177 ! protein targeting to ER GO:0045047 25 9 0,000 0,01359192 0,03838734 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01359192 0,03834302 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01359192 0,03829879 ! T cell selection GO:0045058 27 9 0,000 0,01359192 0,03825467 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,01359192 0,03821065 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01359192 0,03816673 ! glycine catabolic process GO:0006546 15 9 0,000 0,01359192 0,03812291 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01359192 0,03807919 ! endosome organization GO:0007032 20 9 0,000 0,01359192 0,03803557 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01359192 0,03799205 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01359192 0,03794863 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01359192 0,03790531 ! mannose metabolic process GO:0006013 13 9 0,000 0,01359192 0,03786209 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01359192 0,03781897 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01359192 0,03777594 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01359192 0,03773301 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01359192 0,03769018 ! receptor clustering GO:0043113 20 9 0,000 0,01359192 0,03764745 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01359192 0,03760482 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01359192 0,03756228 ! retinol metabolic process GO:0042572 20 9 0,000 0,01359192 0,03751983 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01359192 0,03747749 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01359192 0,03743523 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01359192 0,03739308 ! macrophage differentiation GO:0030225 15 9 0,000 0,01359192 0,03735101 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01359192 0,03730905 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01359192 0,03726717 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01359192 0,03722539 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01359192 0,03718371 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01359192 0,03714212 ! response to amine stimulus GO:0014075 13 9 0,000 0,01359192 0,03710062 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01359192 0,03705921 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01359192 0,03701789 ! erythrocyte development GO:0048821 17 9 0,000 0,01359192 0,03697667 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01359192 0,03693554 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01359192 0,0368945 ! renal water homeostasis GO:0003091 15 9 0,000 0,01359192 0,03685355 ! postreplication repair GO:0006301 25 9 0,000 0,01359192 0,0368127 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01359192 0,03677193 ! icosanoid secretion GO:0032309 15 9 0,000 0,01359192 0,03673125 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01359192 0,03669066 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01359192 0,03665017 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01359192 0,03660976 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01359192 0,03656944 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01359192 0,03652921 ! sterol catabolic process GO:0016127 14 9 0,000 0,01359192 0,03648907 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01359192 0,03644901 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01359192 0,03640905 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01359192 0,03636917 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01359192 0,03632938 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01359192 0,03628967 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01359192 0,03625006 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01359192 0,03621053 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01359192 0,03617108 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01359192 0,03613172 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01359192 0,03609245 ! purine base metabolic process GO:0006144 25 9 0,000 0,01359192 0,03605326 ! pigment granule transport GO:0051904 17 9 0,000 0,01359192 0,03601416 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01359192 0,03597514 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01359192 0,0359362 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01359192 0,03589735 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01359192 0,03585859 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01359192 0,0358199 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01359192 0,03578131 ! mitochondrion localization GO:0051646 18 9 0,000 0,01359192 0,03574279 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01509089 0,03964198 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01509089 0,0395994 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01509089 0,03955692 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01509089 0,03951452 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01509089 0,03947221 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01509089 0,03942999 ! associative learning GO:0008306 21 10 0,000 0,01509089 0,03938787 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01509089 0,03934583 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01509089 0,03930389 ! phosphate transport GO:0006817 24 10 0,000 0,01509089 0,03926203 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01509089 0,03922026 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01509089 0,03917858 ! CTP metabolic process GO:0046036 11 10 0,000 0,01509089 0,03913699 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01509089 0,03909549 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01509089 0,03905407 ! GTP metabolic process GO:0046039 11 10 0,000 0,01509089 0,03901275 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01509089 0,03897151 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01509089 0,03893035 ! social behavior GO:0035176 29 10 0,000 0,01509089 0,03888929 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01509089 0,03884831 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01509089 0,03880742 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01509089 0,03876661 ! androgen metabolic process GO:0008209 17 10 0,000 0,01509089 0,03872589 ! phospholipid efflux GO:0033700 19 10 0,000 0,01509089 0,03868525 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01509089 0,0386447 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01509089 0,03860424 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01509089 0,03856385 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01509089 0,03852356 ! lung alveolus development GO:0048286 26 10 0,000 0,01509089 0,03848335 ! pathogenesis GO:0009405 17 10 0,000 0,01509089 0,03844322 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01509089 0,03840317 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01509089 0,03836321 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01509089 0,03832333 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01509089 0,03828354 ! endoderm development GO:0007492 18 10 0,000 0,01509089 0,03824382 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01509089 0,03820419 ! arginine catabolic process GO:0006527 17 10 0,000 0,01509089 0,03816464 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01509089 0,03812518 ! proline metabolic process GO:0006560 13 10 0,000 0,01509089 0,03808579 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01509089 0,03804649 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01509089 0,03800726 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01509089 0,03796812 ! V(D)J recombination GO:0033151 34 10 0,000 0,01509089 0,03792906 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01509089 0,03789008 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01509089 0,03785118 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01509089 0,03781235 ! B cell proliferation GO:0042100 19 10 0,000 0,01509089 0,03777361 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01509089 0,03773495 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01509089 0,03769636 ! multicellular organism growth GO:0035264 19 10 0,000 0,01509089 0,03765786 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01509089 0,03761943 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01509089 0,03758109 ! ruffle organization GO:0031529 17 10 0,000 0,01509089 0,03754282 ! epithelial cell development GO:0002064 21 10 0,000 0,01509089 0,03750462 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01509089 0,03746651 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01509089 0,03742847 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01509089 0,03739051 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01509089 0,03735263 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01509089 0,03731482 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01509089 0,03727709 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01509089 0,03723944 ! motor axon guidance GO:0008045 22 10 0,000 0,01509089 0,03720186 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01509089 0,03716436 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01509089 0,03712693 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01509089 0,03708958 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01509089 0,03705231 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01509089 0,03701511 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01509089 0,03697798 ! segment specification GO:0007379 15 10 0,000 0,01509089 0,03694093 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01509089 0,03690395 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01509089 0,03686704 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01509089 0,03683021 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01509089 0,03679346 ! response to dsRNA GO:0043331 23 10 0,000 0,01509089 0,03675677 ! DNA ligation GO:0006266 18 10 0,000 0,01509089 0,03672016 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01509089 0,03668363 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01509089 0,03664716 ! melanosome localization GO:0032400 16 10 0,000 0,01509089 0,03661077 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01509089 0,03657445 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01509089 0,0365382 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01509089 0,03650202 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01509089 0,03646592 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01509089 0,03642989 ! induction of an organ GO:0001759 17 10 0,000 0,01509089 0,03639392 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01509089 0,03635803 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01509089 0,03632221 ! protein sumoylation GO:0016925 17 10 0,000 0,01509089 0,03628646 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01509089 0,03625078 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01509089 0,03621517 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01509089 0,03617963 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01509089 0,03614416 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01509089 0,03610876 ! salivary gland development GO:0007431 28 10 0,000 0,01509089 0,03607343 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01509089 0,03603817 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01509089 0,03600297 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01509089 0,03596785 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01509089 0,03593279 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01509089 0,0358978 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01509089 0,03586288 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01509089 0,03582803 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01509089 0,03579325 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01509089 0,03575853 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01509089 0,03572388 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01509089 0,0356893 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01509089 0,03565478 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01509089 0,03562033 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01509089 0,03558595 ! blastocyst formation GO:0001825 18 10 0,000 0,01509089 0,03555163 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01509089 0,03551738 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01509089 0,0354832 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01509089 0,03544908 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01509089 0,03541503 ! response to nicotine GO:0035094 20 10 0,000 0,01509089 0,03538104 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01509089 0,03534712 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01509089 0,03531326 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01658763 0,03877854 ! respiratory burst GO:0045730 17 11 0,000 0,01658763 0,03874147 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01658763 0,03870447 ! neuron fate specification GO:0048665 18 11 0,000 0,01658763 0,03866753 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01658763 0,03863067 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01658763 0,03859388 ! thyroid gland development GO:0030878 26 11 0,000 0,01658763 0,03855716 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01658763 0,03852051 ! synapsis GO:0007129 14 11 0,000 0,01658763 0,03848393 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01658763 0,03844742 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01658763 0,03841097 ! response to pain GO:0048265 27 11 0,000 0,01658763 0,0383746 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01658763 0,03833829 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01658763 0,03830206 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01658763 0,03826589 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01658763 0,03822979 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01658763 0,03819376 ! bone resorption GO:0045453 16 11 0,000 0,01658763 0,03815779 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01658763 0,0381219 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01658763 0,03808607 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01658763 0,03805031 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01658763 0,03801461 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01658763 0,03797898 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01658763 0,03794342 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01658763 0,03790793 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01658763 0,0378725 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01658763 0,03783714 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01658763 0,03780184 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01658763 0,03776661 ! UV protection GO:0009650 20 11 0,000 0,01658763 0,03773145 ! adult heart development GO:0007512 16 11 0,000 0,01658763 0,03769635 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01658763 0,03766132 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01658763 0,03762635 ! macroautophagy GO:0016236 19 11 0,000 0,01658763 0,03759144 ! temperature homeostasis GO:0001659 18 11 0,000 0,01658763 0,0375566 ! behavioral fear response GO:0001662 27 11 0,000 0,01658763 0,03752183 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01658763 0,03748712 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01658763 0,03745247 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01658763 0,03741789 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01658763 0,03738337 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01658763 0,03734892 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01658763 0,03731453 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01658763 0,0372802 ! regulation of organ growth GO:0046620 14 11 0,000 0,01658763 0,03724593 ! pigment granule localization GO:0051875 20 11 0,000 0,01658763 0,03721173 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01658763 0,03717759 ! vasoconstriction GO:0042310 20 11 0,000 0,01658763 0,03714352 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01658763 0,0371095 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01658763 0,03707555 ! embryonic axis specification GO:0000578 19 11 0,000 0,01658763 0,03704166 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01658763 0,03700783 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01658763 0,03697407 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01658763 0,03694036 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01658763 0,03690672 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01658763 0,03687314 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01658763 0,03683961 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01658763 0,03680615 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01658763 0,03677276 ! prophase GO:0051324 17 11 0,000 0,01658763 0,03673942 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01658763 0,03670614 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01658763 0,03667292 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01658763 0,03663976 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01658763 0,03660666 ! apical protein localization GO:0045176 18 11 0,000 0,01658763 0,03657362 ! acid secretion GO:0046717 20 11 0,000 0,01658763 0,03654065 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01658763 0,03650773 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01658763 0,03647487 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01658763 0,03644206 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01658763 0,03640932 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01658763 0,03637664 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01658763 0,03634401 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01658763 0,03631145 ! cholesterol efflux GO:0033344 21 11 0,000 0,01658763 0,03627894 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01658763 0,03624649 ! oocyte development GO:0048599 20 11 0,000 0,01658763 0,0362141 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01658763 0,03618176 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01658763 0,03614949 ! embryonic gut development GO:0048566 19 11 0,000 0,01658763 0,03611727 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01658763 0,03608511 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01658763 0,036053 ! activation of innate immune response GO:0002218 16 11 0,000 0,01658763 0,03602096 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01658763 0,03598897 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01658763 0,03595703 ! lysogeny GO:0030069 22 11 0,000 0,01658763 0,03592516 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01658763 0,03589334 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01658763 0,03586157 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01658763 0,03582986 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01658763 0,03579821 ! nucleus localization GO:0051647 22 11 0,000 0,01658763 0,03576662 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01808213 0,03895472 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01808213 0,0389204 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01808213 0,03888614 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01808213 0,03885194 ! virus-host interaction GO:0019048 30 12 0,000 0,01808213 0,0388178 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,01808213 0,03878372 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01808213 0,0387497 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01808213 0,03871573 ! protein complex disassembly GO:0043241 28 12 0,000 0,01808213 0,03868183 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01808213 0,03864799 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01808213 0,03861421 ! hippocampus development GO:0021766 29 12 0,000 0,01808213 0,03858048 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01808213 0,03854682 ! T cell proliferation GO:0042098 32 12 0,000 0,01808213 0,03851321 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01808213 0,03847966 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01808213 0,03844617 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01808213 0,03841274 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01808213 0,03837937 ! drug transport GO:0015893 16 12 0,000 0,01808213 0,03834605 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01808213 0,0383128 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01808213 0,0382796 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01808213 0,03824645 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01808213 0,03821337 ! focal adhesion formation GO:0048041 37 12 0,000 0,01808213 0,03818034 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01808213 0,03814737 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01808213 0,03811445 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01808213 0,0380816 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01808213 0,0380488 ! lipid digestion GO:0044241 21 12 0,000 0,01808213 0,03801605 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01808213 0,03798336 ! entry into host cell GO:0030260 34 12 0,000 0,01808213 0,03795073 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01808213 0,03791816 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01808213 0,03788564 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01808213 0,03785317 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01808213 0,03782076 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01808213 0,03778841 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01808213 0,03775611 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01808213 0,03772387 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01808213 0,03769168 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01808213 0,03765955 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01808213 0,03762747 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01808213 0,03759545 ! cranial nerve development GO:0021545 23 12 0,000 0,01808213 0,03756348 ! fucose catabolic process GO:0019317 25 12 0,000 0,01808213 0,03753157 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01808213 0,03749971 ! histone acetylation GO:0016573 27 12 0,000 0,01808213 0,0374679 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01808213 0,03743615 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01808213 0,03740445 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01808213 0,0373728 ! zymogen activation GO:0031638 18 12 0,000 0,01808213 0,03734121 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01808213 0,03730967 ! T cell homeostasis GO:0043029 28 12 0,000 0,01808213 0,03727819 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01808213 0,03724676 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01808213 0,03721538 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01808213 0,03718405 ! oocyte differentiation GO:0009994 21 12 0,000 0,01808213 0,03715278 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01808213 0,03712156 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01808213 0,03709039 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01808213 0,03705927 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01808213 0,03702821 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01808213 0,0369972 ! defense response to fungus GO:0050832 15 12 0,000 0,01808213 0,03696624 ! developmental induction GO:0031128 22 12 0,000 0,01808213 0,03693533 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01808213 0,03690447 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01808213 0,03687367 ! response to cold GO:0009409 17 12 0,000 0,01808213 0,03684291 ! establishment of cell polarity GO:0030010 21 12 0,000 0,01808213 0,03681221 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01808213 0,03678156 ! localization within membrane GO:0051668 26 12 0,000 0,01808213 0,03675096 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01957441 0,03975086 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01957441 0,03971784 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01957441 0,03968488 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01957441 0,03965198 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01957441 0,03961913 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01957441 0,03958633 ! peroxisomal transport GO:0043574 28 13 0,000 0,01957441 0,03955359 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01957441 0,0395209 ! cartilage condensation GO:0001502 22 13 0,000 0,01957441 0,03948826 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01957441 0,03945568 ! organelle fusion GO:0048284 36 13 0,000 0,01957441 0,03942315 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01957441 0,03939068 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01957441 0,03935826 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01957441 0,03932589 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01957441 0,03929358 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01957441 0,03926132 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01957441 0,03922911 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01957441 0,03919695 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01957441 0,03916485 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01957441 0,0391328 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01957441 0,03910081 ! methionine metabolic process GO:0006555 31 13 0,000 0,01957441 0,03906886 ! plasma membrane organization GO:0007009 27 13 0,000 0,01957441 0,03903697 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01957441 0,03900513 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01957441 0,03897334 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01957441 0,0389416 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01957441 0,03890991 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01957441 0,03887828 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01957441 0,0388467 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,01957441 0,03881517 ! exocrine system development GO:0035272 34 13 0,000 0,01957441 0,03878369 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01957441 0,03875226 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01957441 0,03872088 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01957441 0,03868955 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01957441 0,03865827 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01957441 0,03862705 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01957441 0,03859587 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01957441 0,03856475 ! protein homotetramerization GO:0051289 24 13 0,000 0,01957441 0,03853367 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01957441 0,03850264 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01957441 0,03847167 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01957441 0,03844074 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01957441 0,03840987 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01957441 0,03837904 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01957441 0,03834826 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01957441 0,03831754 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01957441 0,03828686 ! histone methylation GO:0016571 29 13 0,000 0,01957441 0,03825623 ! gland morphogenesis GO:0022612 31 13 0,000 0,01957441 0,03822565 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01957441 0,03819512 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01957441 0,03816463 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01957441 0,0381342 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01957441 0,03810381 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01957441 0,03807347 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01957441 0,03804319 ! spleen development GO:0048536 24 13 0,000 0,01957441 0,03801294 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01957441 0,03798275 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01957441 0,03795261 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01957441 0,03792251 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01957441 0,03789246 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01957441 0,03786246 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01957441 0,0378325 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01957441 0,0378026 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01957441 0,03777274 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01957441 0,03774292 ! insulin secretion GO:0030073 24 13 0,000 0,01957441 0,03771316 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01957441 0,03768344 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01957441 0,03765377 ! acrosome reaction GO:0007340 19 13 0,000 0,01957441 0,03762414 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01957441 0,03759456 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01957441 0,03756503 ! rRNA transcription GO:0009303 28 14 0,000 0,02106446 0,04039284 ! regulation of S phase GO:0033261 26 14 0,000 0,02106446 0,04036116 ! water transport GO:0006833 21 14 0,000 0,02106446 0,04032953 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02106446 0,04029795 ! non-recombinational repair GO:0000726 29 14 0,000 0,02106446 0,04026641 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02106446 0,04023493 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02106446 0,0402035 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02106446 0,04017211 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02106446 0,04014078 ! lipid localization GO:0010876 32 14 0,000 0,02106446 0,04010949 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,02106446 0,04007825 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02106446 0,04004706 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02106446 0,04001592 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02106446 0,03998483 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02106446 0,03995379 ! arginine metabolic process GO:0006525 21 14 0,000 0,02106446 0,03992279 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02106446 0,03989184 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02106446 0,03986094 ! regulation of heart rate GO:0002027 25 14 0,000 0,02106446 0,03983009 ! fear response GO:0042596 34 14 0,000 0,02106446 0,03979929 ! organic alcohol transport GO:0015850 29 14 0,000 0,02106446 0,03976853 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02106446 0,03973782 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02106446 0,03970716 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02106446 0,03967654 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02106446 0,03964598 ! bone mineralization GO:0030282 18 14 0,000 0,02106446 0,03961546 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02106446 0,03958498 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02106446 0,03955456 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02106446 0,03952418 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02106446 0,03949384 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02106446 0,03946356 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02106446 0,03943332 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02106446 0,03940312 ! ribosome assembly GO:0042255 18 14 0,000 0,02106446 0,03937297 ! cerebellum development GO:0021549 23 14 0,000 0,02106446 0,03934287 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02106446 0,03931282 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02106446 0,03928281 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02106446 0,03925284 ! response to gamma radiation GO:0010332 30 14 0,000 0,02106446 0,03922293 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02106446 0,03919305 ! NADP metabolic process GO:0006739 24 14 0,000 0,02106446 0,03916323 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02106446 0,03913344 ! oxygen transport GO:0015671 22 14 0,000 0,02106446 0,03910371 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02106446 0,03907401 ! male genitalia development GO:0030539 26 14 0,000 0,02106446 0,03904437 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02106446 0,03901477 ! regulation of axon extension GO:0030516 43 14 0,000 0,02106446 0,03898521 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02106446 0,0389557 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02106446 0,03892623 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,02106446 0,03889681 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02255229 0,04161272 ! lactation GO:0007595 30 15 0,000 0,02255229 0,04158131 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,02255229 0,04154996 ! reproductive cellular process GO:0048610 22 15 0,000 0,02255229 0,04151864 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02255229 0,04148738 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02255229 0,04145616 ! superoxide anion generation GO:0042554 22 15 0,000 0,02255229 0,04142499 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02255229 0,04139387 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02255229 0,04136279 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02255229 0,04133176 ! copper ion transport GO:0006825 22 15 0,000 0,02255229 0,04130078 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02255229 0,04126984 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02255229 0,04123895 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02255229 0,04120811 ! sulfate transport GO:0008272 27 15 0,000 0,02255229 0,04117731 ! response to cAMP GO:0051591 25 15 0,000 0,02255229 0,04114656 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02255229 0,04111585 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02255229 0,04108519 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02255229 0,04105458 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02255229 0,04102401 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02255229 0,04099348 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02255229 0,040963 ! vesicle coating GO:0006901 38 15 0,000 0,02255229 0,04093257 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02255229 0,04090218 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02255229 0,04087184 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02255229 0,04084154 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02255229 0,04081129 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02255229 0,04078108 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02255229 0,04075092 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02255229 0,0407208 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02255229 0,04069072 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02255229 0,04066069 ! regulation of vasodilation GO:0042312 27 15 0,000 0,02255229 0,04063071 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02255229 0,04060077 ! histone deacetylation GO:0016575 24 15 0,000 0,02255229 0,04057087 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02255229 0,04054102 ! water homeostasis GO:0030104 28 15 0,000 0,02255229 0,04051121 ! cofactor transport GO:0051181 30 15 0,000 0,02255229 0,04048144 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02255229 0,04045172 ! muscle maintenance GO:0046716 26 15 0,000 0,02255229 0,04042204 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02255229 0,04039241 ! intestinal absorption GO:0050892 31 15 0,000 0,02255229 0,04036281 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02255229 0,04033327 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02255229 0,04030376 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02255229 0,0402743 ! cell killing GO:0001906 32 15 0,000 0,02255229 0,04024488 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02255229 0,0402155 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02255229 0,04018617 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02255229 0,04015688 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02255229 0,04012763 ! actin filament polymerization GO:0030041 27 15 0,000 0,02255229 0,04009843 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02255229 0,04006927 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,0240379 0,04267775 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,0240379 0,04264676 ! positive regulation of cell size GO:0045793 29 16 0,000 0,0240379 0,04261581 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,0240379 0,0425849 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,0240379 0,04255404 ! bone remodeling GO:0046849 28 16 0,000 0,0240379 0,04252323 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,0240379 0,04249246 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,0240379 0,04246174 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,0240379 0,04243106 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,0240379 0,04240042 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,0240379 0,04236983 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,0240379 0,04233928 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,0240379 0,04230878 ! startle response GO:0001964 28 16 0,000 0,0240379 0,04227832 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,0240379 0,0422479 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,0240379 0,04221753 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,0240379 0,0421872 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,0240379 0,04215691 ! protein polyubiquitination GO:0000209 41 16 0,000 0,0240379 0,04212667 ! glutamate metabolic process GO:0006536 25 16 0,000 0,0240379 0,04209647 ! pituitary gland development GO:0021983 30 16 0,000 0,0240379 0,04206632 ! response to osmotic stress GO:0006970 27 16 0,000 0,0240379 0,04203621 ! lysosomal transport GO:0007041 31 16 0,000 0,0240379 0,04200614 ! fructose metabolic process GO:0006000 25 16 0,000 0,0240379 0,04197611 ! L-amino acid transport GO:0015807 33 16 0,000 0,0240379 0,04194613 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0240379 0,04191619 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0240379 0,04188629 ! intermediate filament-based process GO:0045103 36 16 0,000 0,0240379 0,04185644 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,0240379 0,04182663 ! negative regulation of immune response GO:0050777 38 16 0,000 0,0240379 0,04179686 ! axon cargo transport GO:0008088 46 16 0,000 0,0240379 0,04176713 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,0240379 0,04173744 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,0240379 0,0417078 ! DNA replication initiation GO:0006270 28 16 0,000 0,0240379 0,0416782 ! neuron recognition GO:0008038 40 16 0,000 0,0240379 0,04164864 ! mRNA splice site selection GO:0006376 44 16 0,000 0,0240379 0,04161912 ! tissue regeneration GO:0042246 27 16 0,000 0,0240379 0,04158965 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,0240379 0,04156021 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,0240379 0,04153082 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,0240379 0,04150147 ! biomineral formation GO:0031214 22 16 0,000 0,0240379 0,04147216 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,0240379 0,04144289 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,0240379 0,04141367 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,0240379 0,04138448 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0240379 0,04135534 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,0240379 0,04132624 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,0240379 0,04129717 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,0240379 0,04126815 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,0240379 0,04123917 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,0240379 0,04121023 ! peptide hormone processing GO:0016486 27 16 0,000 0,0240379 0,04118133 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02552129 0,04369202 ! metencephalon development GO:0022037 32 17 0,000 0,02552129 0,04366142 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02552129 0,04363087 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,02552129 0,04360036 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02552129 0,04356989 ! signal complex assembly GO:0007172 47 17 0,000 0,02552129 0,04353946 ! filopodium assembly GO:0046847 42 17 0,000 0,02552129 0,04350908 ! endothelial cell migration GO:0043542 31 17 0,000 0,02552129 0,04347874 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02552129 0,04344844 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02552129 0,04341818 ! glial cell development GO:0021782 28 17 0,000 0,02552129 0,04338797 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02552129 0,04335779 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02552129 0,04332766 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02552129 0,04329758 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,02552129 0,04326753 ! myoblast differentiation GO:0045445 50 17 0,000 0,02552129 0,04323752 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02552129 0,04320756 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02552129 0,04317764 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02552129 0,04314776 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02552129 0,04311792 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02552129 0,04308812 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02552129 0,04305836 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02552129 0,04302865 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02552129 0,04299897 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02552129 0,04296934 ! membrane budding GO:0006900 42 17 0,000 0,02552129 0,04293974 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02552129 0,04291019 ! regulation of protein binding GO:0043393 33 17 0,000 0,02552129 0,04288068 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02552129 0,04285121 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02552129 0,04282178 ! genitalia development GO:0048806 32 17 0,000 0,02552129 0,04279239 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02552129 0,04276304 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02552129 0,04273373 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02552129 0,04270446 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02552129 0,04267523 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02552129 0,04264604 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02552129 0,04261689 ! steroid catabolic process GO:0006706 34 17 0,000 0,02552129 0,04258778 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02552129 0,04255871 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02552129 0,04252968 ! gas transport GO:0015669 26 17 0,000 0,02552129 0,04250069 ! organic cation transport GO:0015695 32 17 0,000 0,02552129 0,04247174 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02552129 0,04244282 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02552129 0,04241395 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02552129 0,04238512 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02700247 0,04481456 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02700247 0,04478413 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02700247 0,04475375 ! limbic system development GO:0021761 40 18 0,000 0,02700247 0,04472341 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02700247 0,04469311 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02700247 0,04466285 ! adult walking behavior GO:0007628 36 18 0,000 0,02700247 0,04463263 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02700247 0,04460245 ! heart looping GO:0001947 34 18 0,000 0,02700247 0,04457232 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02700247 0,04454222 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02700247 0,04451217 ! centrosome cycle GO:0007098 26 18 0,000 0,02700247 0,04448215 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02700247 0,04445218 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02700247 0,04442224 ! glycine metabolic process GO:0006544 30 18 0,000 0,02700247 0,04439235 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02700247 0,04436249 ! response to retinoic acid GO:0032526 31 18 0,000 0,02700247 0,04433268 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02700247 0,04430291 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,02700247 0,04427317 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02700247 0,04424348 ! DNA integration GO:0015074 32 18 0,000 0,02700247 0,04421383 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02700247 0,04418421 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02700247 0,04415464 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02700247 0,0441251 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02700247 0,04409561 ! neural crest cell migration GO:0001755 41 18 0,000 0,02700247 0,04406615 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02700247 0,04403674 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02700247 0,04400736 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02700247 0,04397802 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02700247 0,04394872 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02700247 0,04391946 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02700247 0,04389024 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,02700247 0,04386106 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02700247 0,04383191 ! detection of bacterium GO:0016045 22 18 0,000 0,02700247 0,04380281 ! nerve development GO:0021675 34 18 0,000 0,02700247 0,04377374 ! defense response to virus GO:0051607 43 18 0,000 0,02700247 0,04374471 ! microspike assembly GO:0030035 46 18 0,000 0,02700247 0,04371573 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02700247 0,04368677 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,02700247 0,04365786 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02848144 0,04601862 ! positive regulation of translation GO:0045727 31 19 0,000 0,02848144 0,0459882 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02848144 0,04595783 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,02848144 0,04592749 ! neuron maturation GO:0042551 46 19 0,000 0,02848144 0,0458972 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,02848144 0,04586694 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02848144 0,04583673 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02848144 0,04580655 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02848144 0,04577642 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02848144 0,04574632 ! inositol metabolic process GO:0006020 33 19 0,000 0,02848144 0,04571626 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02848144 0,04568625 ! memory GO:0007613 34 19 0,000 0,02848144 0,04565627 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02848144 0,04562633 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02848144 0,04559643 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02848144 0,04556657 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02848144 0,04553675 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,02848144 0,04550697 ! cerebral cortex development GO:0021987 40 19 0,000 0,02848144 0,04547722 ! pigmentation during development GO:0048066 42 19 0,000 0,02848144 0,04544752 ! response to vitamin A GO:0033189 32 19 0,000 0,02848144 0,04541785 ! heme metabolic process GO:0042168 40 19 0,000 0,02848144 0,04538823 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02848144 0,04535864 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02848144 0,04532909 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02848144 0,04529958 ! response to fungus GO:0009620 26 19 0,000 0,02848144 0,04527011 ! peptide cross-linking GO:0018149 39 19 0,000 0,02848144 0,04524067 ! protein export from nucleus GO:0006611 40 19 0,000 0,02848144 0,04521127 ! heart process GO:0003015 32 19 0,000 0,02848144 0,04518192 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02848144 0,0451526 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02848144 0,04512331 ! visual learning GO:0008542 38 19 0,000 0,02848144 0,04509407 ! cellular pigmentation GO:0033059 37 19 0,000 0,02848144 0,04506486 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02848144 0,0450357 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02848144 0,04500657 ! vitamin transport GO:0051180 31 19 0,000 0,02848144 0,04497747 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02848144 0,04494842 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02848144 0,0449194 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,02848144 0,04489042 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02848144 0,04486148 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02848144 0,04483257 ! cilium assembly GO:0042384 38 19 0,000 0,02848144 0,0448037 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02848144 0,04477487 ! protein secretion GO:0009306 45 20 0,000 0,0299582 0,04706616 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,0299582 0,04703591 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,0299582 0,04700571 ! positive regulation of ossification GO:0045778 50 20 0,000 0,0299582 0,04697553 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,0299582 0,0469454 ! skin development GO:0043588 42 20 0,000 0,0299582 0,04691531 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,0299582 0,04688526 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,0299582 0,04685524 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,0299582 0,04682526 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,0299582 0,04679532 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,0299582 0,04676542 ! response to vitamin GO:0033273 36 20 0,000 0,0299582 0,04673556 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,0299582 0,04670573 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,0299582 0,04667595 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,0299582 0,0466462 ! bile acid metabolic process GO:0008206 34 20 0,000 0,0299582 0,04661649 ! response to alkaloid GO:0043279 38 20 0,000 0,0299582 0,04658681 ! retinoid metabolic process GO:0001523 34 20 0,000 0,0299582 0,04655718 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,0299582 0,04652758 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,0299582 0,04649802 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,0299582 0,0464685 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,0299582 0,04643901 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,0299582 0,04640956 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,0299582 0,04638015 ! body fluid secretion GO:0007589 33 20 0,000 0,0299582 0,04635078 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,0299582 0,04632145 ! peptide secretion GO:0002790 38 20 0,000 0,0299582 0,04629215 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,0299582 0,04626288 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,0299582 0,04623366 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,0299582 0,04620447 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,0299582 0,04617532 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,0299582 0,04614621 ! cell-cell junction organization GO:0045216 43 20 0,000 0,0299582 0,04611713 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,0299582 0,04608809 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,0299582 0,04605908 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,0299582 0,04603012 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,0299582 0,04600118 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,0299582 0,04597229 ! regulation of glucose import GO:0046324 30 20 0,000 0,0299582 0,04594343 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,0299582 0,04591461 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,0299582 0,04588582 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,0299582 0,04585707 ! negative regulation of translation GO:0017148 32 20 0,000 0,0299582 0,04582836 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,0299582 0,04579968 ! regulation of cell killing GO:0031341 46 21 0,000 0,03143276 0,04802391 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,03143276 0,0479939 ! hormone secretion GO:0046879 39 21 0,000 0,03143276 0,04796392 ! lipid phosphorylation GO:0046834 43 21 0,000 0,03143276 0,04793398 ! cAMP metabolic process GO:0046058 41 21 0,000 0,03143276 0,04790408 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,03143276 0,04787421 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,03143276 0,04784438 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,03143276 0,04781459 ! ovarian follicle development GO:0001541 39 21 0,000 0,03143276 0,04778484 ! smooth muscle contraction GO:0006939 48 21 0,000 0,03143276 0,04775512 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,03143276 0,04772544 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,03143276 0,0476958 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,03143276 0,04766619 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,03143276 0,04763662 ! plasma membrane fusion GO:0045026 33 21 0,000 0,03143276 0,04760709 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,03143276 0,04757759 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,03143276 0,04754813 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,03143276 0,04751871 ! sensory perception of pain GO:0019233 33 21 0,000 0,03143276 0,04748932 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,03143276 0,04745997 ! diencephalon development GO:0021536 36 21 0,000 0,03143276 0,04743066 ! collagen fibril organization GO:0030199 62 21 0,000 0,03143276 0,04740138 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,03143276 0,04737214 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,03143276 0,04734293 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,03143276 0,04731376 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,03143276 0,04728463 ! collagen catabolic process GO:0030574 29 21 0,000 0,03143276 0,04725553 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,03143276 0,04722647 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,03143276 0,04719744 ! sperm-egg recognition GO:0035036 23 21 0,000 0,03143276 0,04716845 ! actin filament-based movement GO:0030048 47 21 0,000 0,03143276 0,04713949 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,03143276 0,04711057 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,03290512 0,04928707 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,03290512 0,04925687 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,03290512 0,0492267 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,03290512 0,04919658 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,03290512 0,04916649 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,03290512 0,04913643 ! microtubule-based transport GO:0010970 59 22 0,000 0,03290512 0,04910642 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,03290512 0,04907644 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,03290512 0,0490465 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,03290512 0,04901659 ! cellular response to starvation GO:0009267 37 22 0,000 0,03290512 0,04898672 ! vacuolar transport GO:0007034 41 22 0,000 0,03290512 0,04895689 ! central nervous system neuron development GO:0021954 47 22 0,000 0,03290512 0,04892709 ! fucose metabolic process GO:0006004 44 22 0,000 0,03290512 0,04889733 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,03290512 0,0488676 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,03290512 0,04883791 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,03290512 0,04880826 ! ureteric bud development GO:0001657 50 22 0,000 0,03290512 0,04877865 ! cell aging GO:0007569 48 22 0,000 0,03290512 0,04874906 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,03290512 0,04871952 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,03290512 0,04869001 ! cytolysis GO:0019835 27 22 0,000 0,03290512 0,04866054 ! renal system process GO:0003014 42 22 0,000 0,03290512 0,0486311 ! vasodilation GO:0042311 40 22 0,000 0,03290512 0,0486017 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,03290512 0,04857233 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,03290512 0,048543 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,03290512 0,0485137 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,03290512 0,04848444 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,03290512 0,04845522 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,03290512 0,04842603 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,03290512 0,04839687 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,03290512 0,04836775 ! sarcomere organization GO:0045214 32 22 0,000 0,03290512 0,04833867 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,03290512 0,04830962 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,03290512 0,0482806 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,03290512 0,04825162 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,03290512 0,04822268 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,03290512 0,04819377 ! gut development GO:0048565 44 22 0,000 0,03290512 0,04816489 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,03290512 0,04813605 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,03290512 0,04810725 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,03290512 0,04807847 ! protein stabilization GO:0050821 41 22 0,000 0,03290512 0,04804974 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,03437528 0,05016656 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,03437528 0,05013661 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,03437528 0,05010669 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,03437528 0,05007681 ! gluconeogenesis GO:0006094 38 23 0,000 0,03437528 0,05004697 ! glycerol metabolic process GO:0006071 40 23 0,000 0,03437528 0,05001716 ! viral genome replication GO:0019079 44 23 0,000 0,03437528 0,04998739 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,03437528 0,04995765 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,03437528 0,04992795 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,03437528 0,04989829 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,03437528 0,04986865 ! regeneration GO:0031099 42 23 0,000 0,03437528 0,04983906 ! axis specification GO:0009798 43 23 0,000 0,03437528 0,0498095 ! visual behavior GO:0007632 46 23 0,000 0,03437528 0,04977997 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,03437528 0,04975048 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,03437528 0,04972103 ! response to ethanol GO:0045471 47 23 0,000 0,03437528 0,04969161 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,03437528 0,04966222 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,03437528 0,04963287 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,03437528 0,04960355 ! peroxisome organization GO:0007031 43 23 0,000 0,03437528 0,04957427 ! lysosome organization GO:0007040 47 23 0,000 0,03437528 0,04954502 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,03437528 0,04951581 ! vesicle targeting GO:0006903 49 23 0,000 0,03437528 0,04948663 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,03437528 0,04945749 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,03437528 0,04942838 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,03437528 0,0493993 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,03437528 0,04937026 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,03437528 0,04934125 ! DNA modification GO:0006304 36 23 0,000 0,03437528 0,04931228 ! fatty acid transport GO:0015908 47 23 0,000 0,03437528 0,04928334 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,03437528 0,04925444 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,03437528 0,04922557 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,03437528 0,04919673 ! hormone transport GO:0009914 41 23 0,000 0,03437528 0,04916792 ! cell-cell recognition GO:0009988 28 23 0,000 0,03437528 0,04913915 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,03437528 0,04911042 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,03437528 0,04908172 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,03437528 0,04905305 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,03584325 0,05111796 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,03584325 0,05108814 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,03584325 0,05105835 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,03584325 0,05102859 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,03584325 0,05099887 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,03584325 0,05096919 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,03584325 0,05093954 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,03584325 0,05090992 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,03584325 0,05088034 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,03584325 0,05085079 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,03584325 0,05082128 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,03584325 0,0507918 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,03584325 0,05076236 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,03584325 0,05073295 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,03584325 0,05070357 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,03584325 0,05067423 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,03584325 0,05064492 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,03584325 0,05061564 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,03584325 0,0505864 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,03584325 0,0505572 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,03584325 0,05052802 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,03584325 0,05049888 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,03584325 0,05046978 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,03584325 0,0504407 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,03584325 0,05041167 ! membrane depolarization GO:0051899 45 24 0,000 0,03584325 0,05038266 ! pallium development GO:0021543 56 24 0,000 0,03584325 0,05035369 ! oogenesis GO:0048477 44 24 0,000 0,03584325 0,05032475 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,03584325 0,05029584 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,03584325 0,05026697 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,03584325 0,05023813 ! platelet activation GO:0030168 41 24 0,000 0,03584325 0,05020933 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,03584325 0,05018055 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,03584325 0,05015181 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,03584325 0,0501231 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,03584325 0,05009443 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,03584325 0,05006579 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,03584325 0,05003718 ! regulation of amine transport GO:0051952 41 24 0,000 0,03584325 0,0500086 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,03584325 0,04998006 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,03730903 0,05199427 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,03730903 0,05196463 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,03730903 0,05193502 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,03730903 0,05190544 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,03730903 0,0518759 ! leukocyte adhesion GO:0007159 55 25 0,000 0,03730903 0,05184639 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,03730903 0,05181692 ! phototransduction GO:0007602 37 25 0,000 0,03730903 0,05178748 ! keratinization GO:0031424 37 25 0,000 0,03730903 0,05175807 ! vasculogenesis GO:0001570 49 25 0,000 0,03730903 0,0517287 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,03730903 0,05169935 ! vacuole organization GO:0007033 49 25 0,000 0,03730903 0,05167005 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,03730903 0,05164077 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,03730903 0,05161153 ! receptor metabolic process GO:0043112 53 25 0,000 0,03730903 0,05158232 ! chromosome condensation GO:0030261 48 25 0,000 0,03730903 0,05155315 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,03730903 0,051524 ! regulation of behavior GO:0050795 48 25 0,000 0,03730903 0,05149489 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,03730903 0,05146582 ! interaction with host GO:0051701 66 25 0,000 0,03730903 0,05143677 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,03730903 0,05140776 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,03730903 0,05137878 ! immunoglobulin production GO:0002377 62 25 0,000 0,03730903 0,05134984 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,03730903 0,05132092 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,03730903 0,05129204 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,03730903 0,0512632 ! liver development GO:0001889 55 25 0,000 0,03730903 0,05123438 ! protein tetramerization GO:0051262 57 25 0,000 0,03730903 0,0512056 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,03877262 0,05318446 ! myelination GO:0042552 50 26 0,000 0,03877262 0,05315461 ! initiation of viral infection GO:0019059 60 26 0,000 0,03877262 0,0531248 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,03877262 0,05309502 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,03877262 0,05306527 ! molting cycle process GO:0022404 52 26 0,000 0,03877262 0,05303556 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,03877262 0,05300588 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,03877262 0,05297624 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,03877262 0,05294663 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,03877262 0,05291705 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,03877262 0,0528875 ! digestive system process GO:0022600 49 26 0,000 0,03877262 0,05285799 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,03877262 0,05282851 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,03877262 0,05279906 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,03877262 0,05276965 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,03877262 0,05274026 ! neural crest cell development GO:0014032 59 26 0,000 0,03877262 0,05271092 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,03877262 0,0526816 ! negative regulation of cell development GO:0010721 83 26 0,000 0,03877262 0,05265232 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,03877262 0,05262306 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,03877262 0,05259385 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,03877262 0,05256466 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,03877262 0,05253551 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,03877262 0,05250638 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,03877262 0,05247729 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,03877262 0,05244824 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,03877262 0,05241921 ! telomere organization GO:0032200 46 26 0,000 0,03877262 0,05239022 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,03877262 0,05236126 ! neural tube closure GO:0001843 58 26 0,000 0,03877262 0,05233233 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,03877262 0,05230343 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,03877262 0,05227457 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,03877262 0,05224573 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,04023403 0,05418508 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,04023403 0,05415523 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,04023403 0,0541254 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,04023403 0,05409562 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,04023403 0,05406586 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,04023403 0,05403614 ! iron ion transport GO:0006826 65 27 0,000 0,04023403 0,05400645 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,04023403 0,05397679 ! superoxide metabolic process GO:0006801 41 27 0,000 0,04023403 0,05394717 ! tube lumen formation GO:0035148 59 27 0,000 0,04023403 0,05391757 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,04023403 0,05388801 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,04023403 0,05385848 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,04023403 0,05382899 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,04023403 0,05379953 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,04023403 0,0537701 ! response to starvation GO:0042594 47 27 0,000 0,04023403 0,0537407 ! response to toxin GO:0009636 49 27 0,000 0,04023403 0,05371133 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,04023403 0,053682 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,04023403 0,05365269 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,04023403 0,05362342 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,04023403 0,05359418 ! leukocyte proliferation GO:0070661 59 27 0,000 0,04023403 0,05356498 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,04023403 0,0535358 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,04169326 0,05544727 ! neuron fate commitment GO:0048663 52 28 0,000 0,04169326 0,0554171 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,04169326 0,05538696 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,04169326 0,05535686 ! protein amino acid acylation GO:0043543 59 28 0,000 0,04169326 0,05532679 ! vesicle docking GO:0048278 55 28 0,000 0,04169326 0,05529676 ! circadian rhythm GO:0007623 56 28 0,000 0,04169326 0,05526675 ! dendrite development GO:0016358 67 28 0,000 0,04169326 0,05523678 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,04169326 0,05520684 ! fat cell differentiation GO:0045444 57 28 0,000 0,04169326 0,05517694 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,04169326 0,05514706 ! sperm motility GO:0030317 37 28 0,000 0,04169326 0,05511722 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,04169326 0,05508741 ! base-excision repair GO:0006284 41 28 0,000 0,04169326 0,05505764 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,04169326 0,05502789 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,04169326 0,05499818 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,04169326 0,0549685 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,04169326 0,05493885 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,04169326 0,05490923 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,04169326 0,05487965 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,04169326 0,05485009 ! glutathione metabolic process GO:0006749 42 28 0,000 0,04169326 0,05482057 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,04169326 0,05479108 ! lipid oxidation GO:0034440 48 28 0,000 0,04169326 0,05476163 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,04169326 0,0547322 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,04169326 0,05470281 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,04315031 0,05658411 ! translational initiation GO:0006413 66 29 0,000 0,04315031 0,05655375 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,04315031 0,05652343 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,04315031 0,05649314 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,04315031 0,05646288 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,04315031 0,05643265 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,04315031 0,05640246 ! primary neural tube formation GO:0014020 61 29 0,000 0,04315031 0,0563723 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,04315031 0,05634217 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,04315031 0,05631207 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,04315031 0,05628201 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,04315031 0,05625197 ! somitogenesis GO:0001756 52 29 0,000 0,04315031 0,05622197 ! synaptogenesis GO:0007416 46 29 0,000 0,04315031 0,056192 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,04315031 0,05616207 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,04315031 0,05613216 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,04315031 0,05610229 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,04315031 0,05607245 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,04460518 0,05793219 ! phenol metabolic process GO:0018958 56 30 0,000 0,04460518 0,05790141 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,04460518 0,05787066 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,04460518 0,05783995 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,04460518 0,05780926 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,04460518 0,05777861 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,04460518 0,05774799 ! acute-phase response GO:0006953 50 30 0,000 0,04460518 0,0577174 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,04460518 0,05768685 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,04460518 0,05765633 ! myofibril assembly GO:0030239 50 30 0,000 0,04460518 0,05762584 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,04460518 0,05759538 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,04460518 0,05756495 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,04460518 0,05753456 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,04460518 0,0575042 ! phospholipid transport GO:0015914 65 30 0,000 0,04460518 0,05747387 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,04460518 0,05744357 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,04460518 0,05741331 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,04460518 0,05738307 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,04460518 0,05735287 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,04460518 0,0573227 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,04460518 0,05729256 ! regulation of coagulation GO:0050818 52 30 0,000 0,04460518 0,05726246 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,04605788 0,05909633 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,04605788 0,05906531 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,04605788 0,05903432 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,04605788 0,05900336 ! cell junction assembly GO:0034329 85 31 0,000 0,04605788 0,05897244 ! regulation of innate immune response GO:0045088 57 31 0,000 0,04605788 0,05894155 ! ovulation cycle process GO:0022602 55 31 0,000 0,04605788 0,05891069 ! peptide transport GO:0015833 60 31 0,000 0,04605788 0,05887986 ! male gonad development GO:0008584 56 31 0,000 0,04605788 0,05884907 ! iron ion homeostasis GO:0055072 60 31 0,000 0,04605788 0,0588183 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,04605788 0,05878757 ! detection of light stimulus GO:0009583 44 31 0,000 0,04605788 0,05875687 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,04605788 0,05872621 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,04605788 0,05869557 ! natural killer cell activation GO:0030101 50 31 0,000 0,04605788 0,05866497 ! ensheathment of neurons GO:0007272 64 31 0,000 0,04605788 0,0586344 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,04605788 0,05860386 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,04605788 0,05857335 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,04605788 0,05854288 ! eye morphogenesis GO:0048592 65 31 0,000 0,04605788 0,05851243 ! response to heat GO:0009408 54 31 0,000 0,04605788 0,05848202 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,04605788 0,05845164 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,04750842 0,0602612 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,04750842 0,06022993 ! collagen metabolic process GO:0032963 49 32 0,000 0,04750842 0,06019869 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,04750842 0,06016748 ! spindle organization GO:0007051 50 32 0,000 0,04750842 0,06013631 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,04750842 0,06010516 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,04750842 0,06007405 ! metanephros development GO:0001656 81 32 0,000 0,04750842 0,06004298 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,04750842 0,06001193 ! muscle cell development GO:0055001 52 32 0,000 0,04750842 0,05998092 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,04750842 0,05994993 ! ovulation cycle GO:0042698 57 32 0,000 0,04750842 0,05991898 ! peripheral nervous system development GO:0007422 68 32 0,000 0,04750842 0,05988807 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,04750842 0,05985718 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,04750842 0,05982633 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,04750842 0,0597955 ! regulation of pH GO:0006885 56 33 0,000 0,04895679 0,06158674 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,04895679 0,06155504 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,04895679 0,06152338 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,04895679 0,06149174 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,04895679 0,06146014 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,04895679 0,06142858 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,04895679 0,06139704 ! response to ionizing radiation GO:0010212 74 33 0,000 0,04895679 0,06136554 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,04895679 0,06133407 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,04895679 0,06130264 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,04895679 0,06127123 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,04895679 0,06123986 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,04895679 0,06120852 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,04895679 0,06117721 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,04895679 0,06114593 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,050403 0,06292005 ! post-embryonic development GO:0009791 76 34 0,000 0,050403 0,06288791 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,050403 0,06285581 ! cholesterol transport GO:0030301 62 34 0,000 0,050403 0,06282374 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,050403 0,0627917 ! spliceosome assembly GO:0000245 75 34 0,000 0,050403 0,0627597 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,050403 0,06272773 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,050403 0,06269579 ! cell fate specification GO:0001708 56 34 0,000 0,050403 0,06266388 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,050403 0,06263201 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,050403 0,06260017 ! adult locomotory behavior GO:0008344 62 34 0,000 0,050403 0,06256836 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,050403 0,06253658 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,05184705 0,06429561 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,05184705 0,06426299 ! negative regulation of secretion GO:0051048 68 35 0,000 0,05184705 0,0642304 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,05184705 0,06419784 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,05184705 0,06416532 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,05184705 0,06413283 ! membrane docking GO:0022406 69 35 0,000 0,05184705 0,06410038 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,05184705 0,06406795 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,05184705 0,06403556 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,05184705 0,06400321 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,05184705 0,06397088 ! ceramide metabolic process GO:0006672 72 35 0,000 0,05184705 0,06393859 ! telencephalon development GO:0021537 81 35 0,000 0,05184705 0,06390633 ! sterol transport GO:0015918 63 35 0,000 0,05184705 0,0638741 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,05184705 0,06384191 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,05184705 0,06380975 ! placenta development GO:0001890 53 35 0,000 0,05184705 0,06377762 ! vesicle localization GO:0051648 70 35 0,000 0,05184705 0,06374552 ! regulation of muscle development GO:0048634 82 36 0,000 0,05328895 0,06548536 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,05328895 0,06545244 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,05328895 0,06541955 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,05328895 0,06538669 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,05328895 0,06535386 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,05328895 0,06532107 ! positive regulation of cell development GO:0010720 85 36 0,000 0,05328895 0,06528831 ! protein targeting to membrane GO:0006612 75 36 0,000 0,05328895 0,06525559 ! regulation of proteolysis GO:0030162 77 36 0,000 0,05328895 0,06522289 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,05328895 0,06519023 ! aerobic respiration GO:0009060 56 36 0,000 0,05328895 0,06515761 ! cytokine production GO:0001816 68 36 0,000 0,05328895 0,06512501 ! embryonic organ development GO:0048568 67 36 0,000 0,05328895 0,06509245 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,05328895 0,06505992 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,05328895 0,06502742 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,05472869 0,06675097 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,05472869 0,06671766 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,05472869 0,06668438 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,05472869 0,06665114 ! sister chromatid segregation GO:0000819 65 37 0,000 0,05472869 0,06661793 ! odontogenesis GO:0042476 74 37 0,000 0,05472869 0,06658476 ! actomyosin structure organization GO:0031032 68 37 0,000 0,05472869 0,06655161 ! cell junction organization GO:0034330 96 37 0,000 0,05472869 0,0665185 ! tissue remodeling GO:0048771 78 37 0,000 0,05472869 0,06648542 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,05472869 0,06645238 ! female gonad development GO:0008585 71 37 0,000 0,05472869 0,06641937 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,05472869 0,06638639 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,05472869 0,06635344 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,05472869 0,06632053 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,05616628 0,06802887 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,05616628 0,06799516 ! meiosis I GO:0007127 74 38 0,000 0,05616628 0,06796148 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,05616628 0,06792784 ! organic anion transport GO:0015711 82 38 0,000 0,05616628 0,06789423 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,05616628 0,06786065 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,05616628 0,0678271 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,05616628 0,06779359 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,05616628 0,06776011 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,05616628 0,06772667 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,05616628 0,06769326 ! regulation of protein stability GO:0031647 77 38 0,000 0,05616628 0,06765988 ! spermatid development GO:0007286 69 38 0,000 0,05616628 0,06762653 ! pigment metabolic process GO:0042440 87 38 0,000 0,05616628 0,06759322 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,05616628 0,06755994 ! neural tube formation GO:0001841 79 38 0,000 0,05616628 0,06752669 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,05760173 0,06921841 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,05760173 0,06918438 ! negative regulation of binding GO:0051100 71 39 0,000 0,05760173 0,06915038 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,05760173 0,06911642 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,05760173 0,06908249 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,05760173 0,06904859 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,05760173 0,06901473 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,05760173 0,0689809 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,05760173 0,0689471 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,05760173 0,06891334 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,05760173 0,0688796 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,05903504 0,070559 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,05903504 0,0705245 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,05903504 0,07049003 ! learning GO:0007612 82 40 0,000 0,05903504 0,07045559 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,05903504 0,07042119 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,05903504 0,07038682 ! lipid homeostasis GO:0055088 75 40 0,000 0,05903504 0,07035249 ! mismatch repair GO:0006298 58 40 0,000 0,05903504 0,07031818 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,05903504 0,07028392 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,05903504 0,07024968 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,05903504 0,07021548 ! RNA export from nucleus GO:0006405 61 41 0,000 0,0604662 0,07188269 ! mRNA catabolic process GO:0006402 79 41 0,000 0,0604662 0,07184773 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,0604662 0,0718128 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,0604662 0,07177791 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,0604662 0,07174305 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,0604662 0,07170822 ! feeding behavior GO:0007631 69 41 0,000 0,0604662 0,07167343 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,0604662 0,07163867 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,0604662 0,07160394 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,0604662 0,07156925 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,0604662 0,07153459 ! spermatid differentiation GO:0048515 73 41 0,000 0,0604662 0,07149997 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,0604662 0,07146538 ! RNA modification GO:0009451 64 41 0,000 0,0604662 0,07143082 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,06189523 0,07308364 ! ear morphogenesis GO:0042471 64 42 0,000 0,06189523 0,07304833 ! organic ether metabolic process GO:0018904 59 42 0,000 0,06189523 0,07301306 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,06189523 0,07297782 ! T cell differentiation GO:0030217 93 42 0,000 0,06189523 0,07294262 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,06189523 0,07290745 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,06189523 0,07287231 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,06189523 0,07283721 ! regulation of protein secretion GO:0050708 77 42 0,000 0,06189523 0,07280214 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,06189523 0,07276711 ! cytokinesis GO:0000910 84 42 0,000 0,06189523 0,07273211 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,06332213 0,07437306 GO:0090047|positive regulation of transcription regulator activity, ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,06332213 0,07433732 ! regulation of tube size GO:0035150 76 43 0,000 0,06332213 0,07430161 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,06332213 0,07426594 ! glucose transport GO:0015758 66 43 0,000 0,06332213 0,07423031 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,06332213 0,0741947 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,06332213 0,07415914 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,06332213 0,0741236 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,06332213 0,0740881 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,06332213 0,07405264 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,06332213 0,0740172 ! segmentation GO:0035282 78 43 0,000 0,06332213 0,07398181 ! ion transmembrane transport GO:0034220 79 43 0,000 0,06332213 0,07394644 ! neuron migration GO:0001764 85 43 0,000 0,06332213 0,07391111 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,06332213 0,07387582 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,06474689 0,07550199 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,06474689 0,07546596 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,06474689 0,07542998 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,06474689 0,07539402 ! hexose transport GO:0008645 68 44 0,000 0,06474689 0,0753581 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,06474689 0,07532222 ! striated muscle contraction GO:0006941 85 44 0,000 0,06474689 0,07528637 ! phagocytosis GO:0006909 105 44 0,000 0,06474689 0,07525055 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,06474689 0,07521477 ! double-strand break repair GO:0006302 85 44 0,000 0,06474689 0,07517902 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,06616953 0,07679438 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,06616953 0,07675791 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,06616953 0,07672148 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,06616953 0,07668509 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,06616953 0,07664873 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! B cell differentiation GO:0030183 124 45 0,000 0,06616953 0,0766124 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,06616953 0,07657611 ! female gamete generation GO:0007292 71 45 0,000 0,06616953 0,07653985 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,06616953 0,07650363 ! polyol metabolic process GO:0019751 77 45 0,000 0,06616953 0,07646744 ! maintenance of location in cell GO:0051651 101 45 0,000 0,06616953 0,07643128 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,06759005 0,0780352 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,06759005 0,07799834 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,06759005 0,07796151 ! glycolysis GO:0006096 71 46 0,000 0,06759005 0,07792472 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,06759005 0,07788796 ! leukocyte migration GO:0050900 75 46 0,000 0,06759005 0,07785124 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,06759005 0,07781455 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,06759005 0,0777779 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,06759005 0,07774128 ! pigmentation GO:0043473 103 46 0,000 0,06759005 0,0777047 ! neural tube development GO:0021915 91 47 0,000 0,06900844 0,07929803 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,06900844 0,07926075 ! response to insulin stimulus GO:0032868 98 47 0,000 0,06900844 0,07922351 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,07042472 0,08081145 ! positive regulation of defense response GO:0031349 88 48 0,000 0,07042472 0,08077351 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,07042472 0,08073561 ! mitochondrial transport GO:0006839 94 48 0,000 0,07042472 0,08069774 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,07042472 0,08065991 ! cellular component disassembly GO:0022411 89 48 0,000 0,07042472 0,08062211 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,07042472 0,08058435 ! endosome transport GO:0016197 127 48 0,000 0,07042472 0,08054662 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,07042472 0,08050893 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,07042472 0,08047127 ! male sex differentiation GO:0046661 93 48 0,000 0,07042472 0,08043365 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,07042472 0,08039607 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,07042472 0,08035852 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,07042472 0,080321 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,07042472 0,08028352 ! response to calcium ion GO:0051592 94 49 0,000 0,07183888 0,08185745 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,07183888 0,08181929 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,07183888 0,08178116 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,07183888 0,08174307 ! JNK cascade GO:0007254 106 49 0,000 0,07183888 0,08170502 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,07183888 0,081667 ! regulation of action potential GO:0001508 102 50 0,000 0,07325093 0,08323349 ! regulation of ion transport GO:0043269 86 50 0,000 0,07325093 0,0831948 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,07325093 0,08315614 ! endocrine system development GO:0035270 109 50 0,000 0,07325093 0,08311752 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,07325093 0,08307893 ! activation of caspase activity GO:0006919 95 50 0,000 0,07325093 0,08304038 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,07325093 0,08300186 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,07325093 0,08296338 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,07325093 0,08292494 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,07466087 0,08448194 ! viral infectious cycle GO:0019058 104 51 0,000 0,07466087 0,08444282 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,07466087 0,08440375 ! peptide metabolic process GO:0006518 80 51 0,000 0,07466087 0,08436471 ! response to temperature stimulus GO:0009266 84 51 0,000 0,07466087 0,08432571 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,07466087 0,08428674 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,07466087 0,08424781 ! positive regulation of binding GO:0051099 88 52 0,000 0,0760687 0,08579679 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,0760687 0,0857572 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,0760687 0,08571764 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,0760687 0,08567812 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,0760687 0,08563864 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,0760687 0,08559919 ! excretion GO:0007588 87 52 0,000 0,0760687 0,08555978 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,0760687 0,08552041 ! histone modification GO:0016570 104 52 0,000 0,0760687 0,08548107 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,0760687 0,08544177 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,0760687 0,0854025 ! amino acid activation GO:0043038 98 52 0,000 0,0760687 0,08536327 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,07747444 0,08690085 ! positive regulation of growth GO:0045927 96 53 0,000 0,07747444 0,08686097 ! inner ear development GO:0048839 89 53 0,000 0,07747444 0,08682112 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,07747444 0,08678132 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,07747444 0,08674154 ! vesicle organization GO:0016050 127 53 0,000 0,07747444 0,08670181 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,07747444 0,08666211 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,07747444 0,08662245 ! cartilage development GO:0051216 99 53 0,000 0,07747444 0,08658282 ! synapse organization GO:0050808 102 53 0,000 0,07747444 0,08654323 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,07887807 0,0880709 ! regulation of translational initiation GO:0006446 87 54 0,000 0,07887807 0,08803067 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,07887807 0,08799047 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,07887807 0,08795031 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,07887807 0,08791019 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,07887807 0,0878701 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,07887807 0,08783005 ! membrane fusion GO:0006944 122 54 0,000 0,07887807 0,08779004 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,07887807 0,08775006 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,07887807 0,08771012 ! regulation of cell shape GO:0008360 142 54 0,000 0,07887807 0,08767021 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,07887807 0,08763034 ! RNA catabolic process GO:0006401 103 55 0,000 0,08027961 0,08914686 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,08027961 0,08910635 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,08027961 0,08906589 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,08027961 0,08902546 ! cell recognition GO:0008037 98 55 0,000 0,08027961 0,08898507 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,08027961 0,08894471 ! cell maturation GO:0048469 107 55 0,000 0,08027961 0,08890439 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,08027961 0,08886411 ! response to UV GO:0009411 120 55 0,000 0,08027961 0,08882386 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,08027961 0,08878365 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,08167905 0,09029047 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,08167905 0,09024963 ! glucose catabolic process GO:0006007 88 56 0,000 0,08167905 0,09020883 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,08167905 0,09016807 ! regulation of DNA replication GO:0006275 105 56 0,000 0,08167905 0,09012734 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 0,000 0,08307641 0,09162784 ! chloride transport GO:0006821 102 57 0,000 0,08307641 0,09158649 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,08307641 0,09154518 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,08307641 0,09150391 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,08307641 0,09146267 ! heart morphogenesis GO:0003007 105 57 0,000 0,08307641 0,09142147 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,08307641 0,09138031 ! regulation of actin filament length GO:0030832 118 58 0,000 0,08447168 0,09287323 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,08447168 0,09283145 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,08447168 0,09278971 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,08447168 0,092748 ! aging GO:0007568 112 58 0,000 0,08447168 0,09270634 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,08447168 0,09266471 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,08447168 0,09262312 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,08447168 0,09258156 ! maintenance of location GO:0051235 124 58 0,000 0,08447168 0,09254005 ! nuclear export GO:0051168 110 59 0,000 0,08586486 0,09402414 ! establishment of organelle localization GO:0051656 122 59 0,000 0,08586486 0,09398201 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,08725596 0,09546185 ! lipid modification GO:0030258 112 60 0,000 0,08725596 0,09541912 ! DNA catabolic process GO:0006308 94 60 0,000 0,08725596 0,09537643 ! regulation of endocytosis GO:0030100 104 60 0,000 0,08725596 0,09533377 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,08725596 0,09529116 ! adult behavior GO:0030534 104 60 0,000 0,08725596 0,09524858 ! kidney development GO:0001822 133 60 0,000 0,08725596 0,09520604 ! positive regulation of secretion GO:0051047 110 61 0,000 0,08864499 0,09667844 ! regulation of cellular component size GO:0032535 125 61 0,000 0,08864499 0,0966353 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,08864499 0,0965922 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,08864499 0,09654913 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,08864499 0,09650611 ! regulation of heart contraction GO:0008016 123 61 0,000 0,08864499 0,09646312 ! camera-type eye development GO:0043010 126 61 0,000 0,08864499 0,09642017 ! proton transport GO:0015992 117 61 0,000 0,08864499 0,09637726 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,08864499 0,09633439 ! viral reproductive process GO:0022415 132 62 0,000 0,09003194 0,09779815 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,09003194 0,09775468 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,09003194 0,09771125 ! tRNA processing GO:0008033 102 62 0,000 0,09003194 0,09766786 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,09003194 0,09762451 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,09141682 0,0990822 ! regulation of mitosis GO:0007088 112 63 0,000 0,09141682 0,09903827 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,09141682 0,09899437 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,09141682 0,0989505 ! hydrogen transport GO:0006818 121 64 0,000 0,09279963 0,10040279 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,09279963 0,10035834 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,09279963 0,10031394 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,09279963 0,10026957 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,09279963 0,10022524 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,09418037 0,10167152 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,09418037 0,10162661 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,09418037 0,10158175 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,09418037 0,10153692 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,09418037 0,10149213 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,09418037 0,10144738 ! ear development GO:0043583 114 66 0,000 0,09555906 0,10288708 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,09555906 0,10284175 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,09555906 0,10279647 ! gonad development GO:0008406 115 66 0,000 0,09555906 0,10275122 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,09693568 0,1041856 ! activation of MAPK activity GO:0000187 124 67 0,000 0,09693568 0,10413978 ! chromosome segregation GO:0007059 127 67 0,000 0,09693568 0,10409401 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,09693568 0,10404827 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,09693568 0,10400257 ! secondary metabolic process GO:0019748 125 67 0,000 0,09693568 0,10395692 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,09693568 0,1039113 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,09831024 0,10533856 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,09831024 0,10529238 ! hexose catabolic process GO:0019320 113 68 0,000 0,09831024 0,10524624 ! extracellular matrix organization GO:0030198 146 68 0,000 0,09831024 0,10520014 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,09831024 0,10515408 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,09831024 0,10510806 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,09831024 0,10506209 ! viral reproduction GO:0016032 142 68 0,000 0,09831024 0,10501615 ! regulation of lipase activity GO:0060191 137 68 0,000 0,09831024 0,10497025 ! adaptive immune response GO:0002250 126 68 0,000 0,09831024 0,10492439 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,09831024 0,10487857 ! cell projection assembly GO:0030031 138 68 0,000 0,09831024 0,10483279 ! negative regulation of cell size GO:0045792 144 69 0,000 0,09968276 0,10624999 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,09968276 0,10620365 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,09968276 0,10615736 ! lung development GO:0030324 165 69 0,000 0,09968276 0,1061111 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,09968276 0,10606488 ! urogenital system development GO:0001655 149 69 0,000 0,09968276 0,10601871 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,09968276 0,10597257 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,09968276 0,10592648 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,09968276 0,10588042 ! developmental maturation GO:0021700 128 69 0,000 0,09968276 0,10583441 ! single fertilization GO:0007338 83 69 0,000 0,09968276 0,10578843 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,10105322 0,10719627 ! cell redox homeostasis GO:0045454 114 70 0,000 0,10105322 0,10714975 ! germ cell development GO:0007281 133 70 0,000 0,10105322 0,10710326 ! activation of immune response GO:0002253 120 70 0,000 0,10105322 0,10705681 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,10105322 0,10701041 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,10242163 0,1084125 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,10242163 0,10836555 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,10242163 0,10831864 ! carbohydrate transport GO:0008643 114 72 0,000 0,103788 0,10971618 ! respiratory tube development GO:0030323 171 72 0,000 0,103788 0,10966872 ! actin filament organization GO:0007015 167 72 0,000 0,103788 0,10962131 ! B cell activation GO:0042113 179 72 0,000 0,103788 0,10957394 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,103788 0,1095266 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,103788 0,10947931 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,103788 0,10943206 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,103788 0,10938485 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,103788 0,10933768 ! humoral immune response GO:0006959 115 73 0,000 0,10515233 0,11072722 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,10515233 0,11067951 ! regulation of immune effector process GO:0002697 156 73 0,000 0,10515233 0,11063184 ! acute inflammatory response GO:0002526 118 74 0,000 0,10651462 0,11201688 ! amino acid transport GO:0006865 148 74 0,000 0,10651462 0,11196868 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,10651462 0,11192052 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,10651462 0,11187241 ! respiratory system development GO:0060541 175 74 0,000 0,10651462 0,11182433 ! organelle localization GO:0051640 155 74 0,000 0,10651462 0,1117763 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,10787487 0,11315514 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,10787487 0,11310657 ! reproductive structure development GO:0048608 131 75 0,000 0,10787487 0,11305805 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,10787487 0,11300957 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,10787487 0,11296113 ! eye development GO:0001654 155 75 0,000 0,10787487 0,11291273 ! axon guidance GO:0007411 162 75 0,000 0,10787487 0,11286438 ! rhythmic process GO:0048511 142 75 0,000 0,10787487 0,11281606 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,1092331 0,11418761 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,1092331 0,11413877 ! learning or memory GO:0007611 161 76 0,000 0,1092331 0,11408998 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,1092331 0,11404122 ! regulation of blood pressure GO:0008217 134 76 0,000 0,1092331 0,1139925 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,1092331 0,11394383 ! amine catabolic process GO:0009310 136 77 0,000 0,11058929 0,11530927 ! neurotransmitter transport GO:0006836 142 77 0,000 0,11058929 0,11526008 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,11058929 0,11521093 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,11058929 0,11516182 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,11058929 0,11511275 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,11058929 0,11506373 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,11058929 0,11501474 ! regulation of catabolic process GO:0009894 173 77 0,000 0,11058929 0,1149658 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,11194345 0,11632406 ! antigen processing and presentation GO:0019882 117 78 0,000 0,11194345 0,1162746 ! fertilization GO:0009566 99 78 0,000 0,11194345 0,11622518 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,11194345 0,11617581 ! blood coagulation GO:0007596 151 79 0,000 0,11329559 0,11752915 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,11329559 0,11747926 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,11329559 0,11742942 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,11329559 0,11737962 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,11329559 0,11732986 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,11329559 0,11728014 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,11464572 0,11862748 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,11464572 0,11857726 ! meiosis GO:0007126 143 81 0,000 0,11599382 0,11992082 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,11599382 0,11987009 ! response to hypoxia GO:0001666 178 81 0,000 0,11599382 0,11981941 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,11599382 0,11976877 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,11733991 0,12110747 ! protein import into nucleus GO:0006606 174 82 0,000 0,11733991 0,12105633 ! meiotic cell cycle GO:0051321 144 82 0,000 0,11733991 0,12100523 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,11868398 0,12233965 ! exocytosis GO:0006887 153 83 0,000 0,11868398 0,12228805 ! response to drug GO:0042493 149 83 0,000 0,11868398 0,1222365 ! response to oxygen levels GO:0070482 183 83 0,000 0,11868398 0,12218499 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,11868398 0,12213352 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,11868398 0,12208209 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,11868398 0,12203071 ! nuclear import GO:0051170 177 83 0,000 0,11868398 0,12197937 ! inorganic anion transport GO:0015698 156 83 0,000 0,11868398 0,12192808 ! response to metal ion GO:0010038 158 84 0,000 0,12002605 0,123255 ! T cell activation GO:0042110 189 84 0,000 0,12002605 0,12320321 ! response to nutrient GO:0007584 135 84 0,000 0,12002605 0,12315147 ! digestion GO:0007586 130 84 0,000 0,12002605 0,12309977 ! regulation of ligase activity GO:0051340 147 84 0,000 0,12002605 0,12304811 ! hemostasis GO:0007599 165 85 0,000 0,12136611 0,12436972 ! negative regulation of transport GO:0051051 164 85 0,000 0,12136611 0,12431757 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,12136611 0,12426547 ! negative regulation of growth GO:0045926 168 85 0,000 0,12136611 0,12421341 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,12136611 0,1241614 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,12136611 0,12410942 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,12136611 0,1240575 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,12136611 0,12400561 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,12270417 0,12532036 ! regulation of lyase activity GO:0051339 169 86 0,000 0,12270417 0,12526799 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,12270417 0,12521566 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,12404023 0,12652621 ! mitochondrion organization GO:0007005 159 87 0,000 0,12404023 0,12647341 ! alcohol catabolic process GO:0046164 142 87 0,000 0,12404023 0,12642064 ! cellular respiration GO:0045333 143 88 0,000 0,12537429 0,12772702 ! amine biosynthetic process GO:0009309 146 88 0,000 0,12537429 0,12767378 ! sensory perception of smell GO:0007608 117 88 0,000 0,12537429 0,12762058 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,12670636 0,1289228 ! regulation of DNA binding GO:0051101 167 89 0,000 0,12670636 0,12886912 ! tube morphogenesis GO:0035239 194 89 0,000 0,12670636 0,1288155 ! cellular defense response GO:0006968 123 89 0,000 0,12670636 0,12876191 ! protein localization in nucleus GO:0034504 192 89 0,000 0,12670636 0,12870837 ! regulation of neurological system process GO:0031644 175 89 0,000 0,12670636 0,12865488 ! response to inorganic substance GO:0010035 173 90 0,000 0,12803644 0,1299514 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,12803644 0,12989743 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,12803644 0,12984351 ! response to unfolded protein GO:0006986 139 90 0,000 0,12803644 0,12978963 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,12803644 0,1297358 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,12936452 0,13102717 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 220 91 0,000 0,12936452 0,13097287 ! defense response to bacterium GO:0042742 112 91 0,000 0,12936452 0,13091861 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,13069063 0,13220588 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,13201475 0,13349008 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,13201475 0,13343485 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,13201475 0,13337966 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,13201475 0,13332453 ! vitamin metabolic process GO:0006766 153 93 0,000 0,13201475 0,13326943 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,13333689 0,13454854 ! female pregnancy GO:0007565 166 94 0,000 0,13333689 0,13449299 ! sterol metabolic process GO:0016125 166 94 0,000 0,13333689 0,13443748 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,13333689 0,13438202 ! regulation of membrane potential GO:0042391 179 94 0,000 0,13333689 0,1343266 ! regulation of defense response GO:0031347 171 95 0,000 0,13465705 0,13560065 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,13465705 0,13554478 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,13465705 0,13548895 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,13465705 0,13543317 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,13465705 0,13537744 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,13465705 0,13532175 ! sex differentiation GO:0007548 171 96 0,000 0,13597524 0,13659026 ! response to protein stimulus GO:0051789 158 96 0,000 0,13597524 0,13653412 ! regulation of T cell activation GO:0050863 175 96 0,000 0,13597524 0,13647803 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,13729146 0,13774252 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,13729146 0,13768598 ! leukocyte differentiation GO:0002521 232 98 0,000 0,13860571 0,13894697 ! interphase of mitotic cell cycle GO:0051329 224 98 0,000 0,13860571 0,13888997 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,13860571 0,13883303 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,14122832 0,14140196 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,14122832 0,14134404 ! positive regulation of immune response GO:0050778 175 100 0,000 0,14122832 0,14128615 ! hormone metabolic process GO:0042445 171 100 0,000 0,14122832 0,14122832