pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/75-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! response to estradiol stimulus GO:0032355 7 7 2,000 1,867E-06 3,441E-03 ! MAPKKK cascade GO:0000165 82 81 4,000 1,316E-05 0,012126 ! ectoderm development GO:0007398 99 99 4,000 3,5E-05 0,02150365 ! response to estrogen stimulus GO:0043627 23 23 2,000 9,061E-05 0,0417478 ! JAK-STAT cascade GO:0007259 26 25 2,000 1,171E-04 0,04314786 ! interaction with symbiont GO:0051702 5 5 1,000 1,473E-04 0,0452311 ! positive regulation of axonogenesis GO:0050772 5 5 1,000 1,473E-04 0,03876951 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 1,000 1,473E-04 0,03392332 ! regulation of DNA replication initiation GO:0030174 5 5 1,000 1,473E-04 0,03015406 ! positive regulation of T-helper cell differentiation GO:0045624 5 5 1,000 1,473E-04 0,02713866 GO:0045622|regulation of T-helper cell differentiation, ! pyrimidine base metabolic process GO:0006206 5 5 1,000 1,473E-04 0,02467151 ! B cell receptor signaling pathway GO:0050853 5 5 1,000 1,473E-04 0,02261555 ! mitochondrion localization GO:0051646 5 5 1,000 1,473E-04 0,02087589 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 2,000 1,654E-04 0,02177747 GO:0007254|JNK cascade, ! response to temperature stimulus GO:0009266 30 30 2,000 2,039E-04 0,0250584 ! cartilage condensation GO:0001502 7 6 1,000 2,203E-04 0,02538088 ! response to dsRNA GO:0043331 6 6 1,000 2,203E-04 0,02388788 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 1,000 2,203E-04 0,02256078 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! regulation of T-helper 2 type immune response GO:0002828 6 6 1,000 2,203E-04 0,02137337 ! hair follicle morphogenesis GO:0031069 7 7 1,000 3,077E-04 0,02835775 ! cAMP biosynthetic process GO:0006171 7 7 1,000 3,077E-04 0,02700738 ! cell killing GO:0001906 7 7 1,000 3,077E-04 0,02577977 ! T cell receptor signaling pathway GO:0050852 7 7 1,000 3,077E-04 0,02465891 ! response to steroid hormone stimulus GO:0048545 35 35 2,000 3,245E-04 0,02491931 ! negative regulation of muscle development GO:0048635 8 8 1,000 4,093E-04 0,03017504 ! organelle localization GO:0051640 41 40 2,000 4,835E-04 0,03427221 ! lactation GO:0007595 10 9 1,000 5,25E-04 0,03583572 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 5,25E-04 0,03455588 ! L-glutamate transport GO:0015813 9 9 1,000 5,25E-04 0,0333643 GO:0015800|acidic amino acid transport, ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 1,000 5,25E-04 0,03225215 ! DNA replication initiation GO:0006270 9 9 1,000 5,25E-04 0,03121176 ! estrogen receptor signaling pathway GO:0030520 9 9 1,000 5,25E-04 0,03023639 ! anti-apoptosis GO:0006916 100 99 3,000 5,491E-04 0,03066431 ! cAMP metabolic process GO:0046058 10 10 1,000 6,547E-04 0,03548615 ! epidermis morphogenesis GO:0048730 10 10 1,000 6,547E-04 0,03447226 ! embryo implantation GO:0007566 11 10 1,000 6,547E-04 0,03351469 ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 1,000 6,547E-04 0,03260889 ! regulation of epidermis development GO:0045682 10 10 1,000 6,547E-04 0,03175076 ! nerve development GO:0021675 10 10 1,000 6,547E-04 0,03093664 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 1,000 6,547E-04 0,03016322 ! protein stabilization GO:0050821 10 10 1,000 6,547E-04 0,02942754 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 7,982E-04 0,03502569 ! skin development GO:0043588 11 11 1,000 7,982E-04 0,03421113 ! cellular response to starvation GO:0009267 11 11 1,000 7,982E-04 0,03343361 ! response to lipopolysaccharide GO:0032496 11 11 1,000 7,982E-04 0,03269064 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 1,000 7,982E-04 0,03197997 ! interaction with host GO:0051701 11 11 1,000 7,982E-04 0,03129955 ! regulation of alpha-beta T cell activation GO:0046634 12 12 1,000 9,555E-04 0,03668801 ! regulation of tumor necrosis factor production GO:0032680 12 12 1,000 9,555E-04 0,03593927 ! G1 phase GO:0051318 13 12 1,000 9,555E-04 0,03522049 ! negative regulation of DNA replication GO:0008156 13 13 1,000 1,127E-03 0,04070936 ! nucleobase metabolic process GO:0009112 13 13 1,000 1,127E-03 0,03992649 ! regulation of axonogenesis GO:0050770 14 13 1,000 1,127E-03 0,03917316 ! positive regulation of neurogenesis GO:0050769 13 13 1,000 1,127E-03 0,03844773 ! activation of JUN kinase activity GO:0007257 13 13 1,000 1,127E-03 0,03774868 ! negative regulation of cytokine production GO:0001818 13 13 1,000 1,127E-03 0,0370746 ! telomere organization GO:0032200 13 13 1,000 1,127E-03 0,03642417 GO:0000723|telomere maintenance, ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 1,17E-03 0,03718438 ! regulation of interferon-gamma production GO:0032649 14 14 1,000 1,311E-03 0,04095509 ! regulation of neuron projection development GO:0010975 15 14 1,000 1,311E-03 0,0402725 ! hair cycle GO:0042633 14 14 1,000 1,311E-03 0,0396123 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 1,000 1,311E-03 0,03897339 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 1,000 1,311E-03 0,03835477 GO:0033189|response to vitamin A, ! response to molecule of bacterial origin GO:0002237 14 14 1,000 1,311E-03 0,03775547 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 1,509E-03 0,0427901 ! response to vitamin GO:0033273 15 15 1,000 1,509E-03 0,04214176 ! response to starvation GO:0042594 15 15 1,000 1,509E-03 0,04151278 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 1,000 1,509E-03 0,0409023 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 1,509E-03 0,04030951 GO:0090048|negative regulation of transcription regulator activity, ! vesicle targeting GO:0006903 17 16 1,000 1,721E-03 0,04530014 ! positive regulation of cell development GO:0010720 16 16 1,000 1,721E-03 0,04466211 ! lymphocyte proliferation GO:0046651 16 16 1,000 1,721E-03 0,0440418 ! cellular response to nutrient levels GO:0031669 16 16 1,000 1,721E-03 0,04343849 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 1,721E-03 0,04285149 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 1,000 1,721E-03 0,04228013 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 1,945E-03 0,04717272 ! immune response-activating signal transduction GO:0002757 17 17 1,000 1,945E-03 0,04656009 GO:0002764|immune response-regulating signal transduction, ! regulation of cell projection organization GO:0031344 19 18 1,000 2,183E-03 0,05158363 ! mononuclear cell proliferation GO:0032943 18 18 1,000 2,183E-03 0,05093067 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 1,000 2,183E-03 0,05029404 ! negative regulation of DNA binding GO:0043392 19 18 1,000 2,183E-03 0,04967312 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,183E-03 0,04906735 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 2,183E-03 0,04847618 ! establishment of vesicle localization GO:0051650 19 18 1,000 2,183E-03 0,04789908 ! Ras protein signal transduction GO:0007265 69 67 2,000 2,185E-03 0,04736806 ! response to nutrient levels GO:0031667 69 69 2,000 2,377E-03 0,05093776 ! activation of adenylate cyclase activity GO:0007190 19 19 1,000 2,434E-03 0,05156341 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 2,434E-03 0,05097746 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 2,434E-03 0,05040468 ! positive regulation of T cell differentiation GO:0045582 19 19 1,000 2,434E-03 0,04984463 ! regulation of protein stability GO:0031647 19 19 1,000 2,434E-03 0,04929688 ! response to heat GO:0009408 19 19 1,000 2,434E-03 0,04876105 ! vesicle localization GO:0051648 20 19 1,000 2,434E-03 0,04823673 ! response to extracellular stimulus GO:0009991 72 72 2,000 2,685E-03 0,05263403 ! regulation of muscle development GO:0048634 21 20 1,000 2,698E-03 0,05234131 ! negative regulation of binding GO:0051100 21 20 1,000 2,698E-03 0,05179609 ! cyclic nucleotide metabolic process GO:0009187 20 20 1,000 2,698E-03 0,05126211 ! detection of abiotic stimulus GO:0009582 21 20 1,000 2,698E-03 0,05073903 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 2,698E-03 0,05022651 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 1,000 2,975E-03 0,05482568 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 1,000 2,975E-03 0,05428285 ! organic anion transport GO:0015711 21 21 1,000 2,975E-03 0,05375066 ! DNA integrity checkpoint GO:0031570 21 21 1,000 2,975E-03 0,05322881 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 1,000 2,975E-03 0,052717 ! respiratory gaseous exchange GO:0007585 22 22 1,000 3,264E-03 0,05729777 ! regulation of adaptive immune response GO:0002819 22 22 1,000 3,264E-03 0,05675722 ! detection of external stimulus GO:0009581 23 22 1,000 3,264E-03 0,05622678 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 1,000 3,264E-03 0,05570616 ! cytokine production GO:0001816 22 22 1,000 3,264E-03 0,0551951 ! regulation of immune response GO:0050776 78 78 2,000 3,371E-03 0,05648255 ! regulation of JNK cascade GO:0046328 25 23 1,000 3,567E-03 0,05921927 ! cell projection assembly GO:0030031 25 23 1,000 3,567E-03 0,05869053 ! lymphocyte activation GO:0046649 82 81 2,000 3,751E-03 0,06118346 ! mitochondrial transport GO:0006839 24 24 1,000 3,882E-03 0,06275097 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 3,882E-03 0,06220531 ! positive regulation of cytokine production GO:0001819 25 25 1,000 4,209E-03 0,06686986 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 4,298E-03 0,06769737 ! positive regulation of protein kinase activity GO:0045860 89 86 2,000 4,441E-03 0,06936876 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 4,441E-03 0,06878583 ! regulation of T cell differentiation GO:0045580 26 26 1,000 4,549E-03 0,06985869 ! maintenance of location in cell GO:0051651 27 26 1,000 4,549E-03 0,06928134 ! positive regulation of transferase activity GO:0051347 91 88 2,000 4,738E-03 0,07156917 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 2,000 4,738E-03 0,07098731 ! protein amino acid autophosphorylation GO:0046777 28 28 1,000 5,265E-03 0,07825126 ! cartilage development GO:0051216 29 28 1,000 5,265E-03 0,07762525 ! positive regulation of immune system process GO:0002684 92 92 2,000 5,365E-03 0,07848017 ! DNA-dependent DNA replication GO:0006261 29 29 1,000 5,641E-03 0,08186445 ! epidermis development GO:0008544 94 94 2,000 5,697E-03 0,08203224 ! skeletal system morphogenesis GO:0048705 31 30 1,000 6,03E-03 0,08614391 ! immunoglobulin mediated immune response GO:0016064 30 30 1,000 6,03E-03 0,08548126 GO:0019724|B cell mediated immunity, ! establishment of organelle localization GO:0051656 31 30 1,000 6,03E-03 0,08482873 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 6,398E-03 0,08932363 ! regulation of translational initiation GO:0006446 31 31 1,000 6,43E-03 0,08910017 ! B cell activation GO:0042113 31 31 1,000 6,43E-03 0,08843525 ! aging GO:0007568 32 31 1,000 6,43E-03 0,08778017 ! regulation of DNA replication GO:0006275 32 31 1,000 6,43E-03 0,08713473 ! regulation of heart contraction GO:0008016 31 31 1,000 6,43E-03 0,08649871 ! response to hormone stimulus GO:0009725 102 100 2,000 6,766E-03 0,0903632 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 6,842E-03 0,09071864 ! maintenance of location GO:0051235 33 32 1,000 6,842E-03 0,09007065 ! regulation of cellular response to stress GO:0080135 35 33 1,000 7,266E-03 0,09497233 ! amino acid transport GO:0006865 33 33 1,000 7,266E-03 0,09430351 ! activation of protein kinase activity GO:0032147 35 33 1,000 7,266E-03 0,09364405 ! regulation of neuron differentiation GO:0045664 34 33 1,000 7,266E-03 0,09299374 ! response to metal ion GO:0010038 34 34 1,000 7,701E-03 0,09788813 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 7,701E-03 0,09721766 ! detection of stimulus GO:0051606 36 34 1,000 7,701E-03 0,09655631 ! mesoderm development GO:0007498 35 35 1,000 8,149E-03 0,10147136 ! multicellular organism reproduction GO:0032504 36 35 1,000 8,149E-03 0,10079034 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 1,000 8,149E-03 0,10011841 ! response to inorganic substance GO:0010035 36 36 1,000 8,607E-03 0,10505219 ! female pregnancy GO:0007565 37 36 1,000 8,607E-03 0,10436106 ! activation of immune response GO:0002253 36 36 1,000 8,607E-03 0,10367896 ! coagulation GO:0050817 39 36 1,000 8,607E-03 0,10300572 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 9,077E-03 0,10792885 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 1,000 9,077E-03 0,10723699 GO:0090046|regulation of transcription regulator activity, ! lymphocyte mediated immunity GO:0002449 37 37 1,000 9,077E-03 0,10655396 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 9,077E-03 0,10587956 ! adaptive immune response GO:0002250 37 37 1,000 9,077E-03 0,10521365 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! axon guidance GO:0007411 39 38 1,000 9,558E-03 0,11009917 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 9,558E-03 0,10941533 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,01005068 0,11434201 ! hemostasis GO:0007599 42 39 1,000 0,01005068 0,11364053 ! activation of MAPK activity GO:0000187 39 39 1,000 0,01005068 0,1129476 ! respiratory tube development GO:0030323 40 39 1,000 0,01005068 0,11226307 ! response to unfolded protein GO:0006986 39 39 1,000 0,01005068 0,11158678 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 0,01005068 0,1109186 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,01005068 0,11025837 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,01005068 0,10960595 ! positive regulation of T cell activation GO:0050870 39 39 1,000 0,01005068 0,10896121 ! protein oligomerization GO:0051259 39 39 1,000 0,01005068 0,10832401 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,01055422 0,11308967 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,01055422 0,11243597 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,01106878 0,11723998 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 1,000 0,01106878 0,11657004 ! leukocyte mediated immunity GO:0002443 41 41 1,000 0,01106878 0,11590771 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,01159427 0,12072455 ! response to protein stimulus GO:0051789 42 42 1,000 0,01159427 0,12004633 ! respiratory electron transport chain GO:0022904 43 42 1,000 0,01159427 0,11937568 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,01213062 0,12420405 ! positive regulation of lymphocyte activation GO:0051251 44 44 1,000 0,01267773 0,12908866 ! regulation of DNA binding GO:0051101 47 45 1,000 0,01323551 0,1340277 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,01323551 0,13329531 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,01380388 0,13826388 ! amine transport GO:0015837 47 47 1,000 0,01438276 0,14328339 ! ossification GO:0001503 50 49 1,000 0,01557169 0,15429371 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,01557169 0,15346861 ! response to nutrient GO:0007584 49 49 1,000 0,01557169 0,15265229 ! response to bacterium GO:0009617 50 49 1,000 0,01557169 0,15184461 ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 0,01557169 0,15104543 ! positive regulation of cell activation GO:0050867 49 49 1,000 0,01557169 0,15025461 GO:0002696|positive regulation of leukocyte activation, ! regulation of DNA metabolic process GO:0051052 51 50 1,000 0,01618158 0,15532632 ! T cell activation GO:0042110 51 50 1,000 0,01618158 0,15452152 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,01618158 0,15372501 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,01618158 0,15293668 ! positive regulation of immune response GO:0050778 51 51 1,000 0,01680164 0,15798681 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,01680164 0,15718485 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 1,000 0,01680164 0,15639099 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,01743178 0,16144103 ! regulation of T cell activation GO:0050863 53 53 1,000 0,01807192 0,16653276 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 1,000 0,01938189 0,17771557 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! rRNA transcription GO:0009303 5 5 0,000 0,0194743 0,17767891 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,0194743 0,17680365 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,0194743 0,17593696 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,0194743 0,17507874 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,0194743 0,17422884 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,0194743 0,17338715 ! reproductive cellular process GO:0048610 5 5 0,000 0,0194743 0,17255356 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,0194743 0,17172795 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,0194743 0,17091019 ! prostate gland development GO:0030850 5 5 0,000 0,0194743 0,17010019 ! metencephalon development GO:0022037 5 5 0,000 0,0194743 0,16929783 ! water transport GO:0006833 5 5 0,000 0,0194743 0,16850301 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,0194743 0,16771561 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,0194743 0,16693554 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,0194743 0,16616269 ! glycerol metabolic process GO:0006071 5 5 0,000 0,0194743 0,16539696 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,0194743 0,16463826 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,0194743 0,16388649 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,0194743 0,16314155 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,0194743 0,16240335 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,0194743 0,1616718 ! filopodium assembly GO:0046847 7 5 0,000 0,0194743 0,16094682 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,0194743 0,16022831 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,0194743 0,15951618 ! GTP metabolic process GO:0046039 5 5 0,000 0,0194743 0,15881036 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,0194743 0,15811075 ! mRNA stabilization GO:0048255 5 5 0,000 0,0194743 0,15741728 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,0194743 0,15672987 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,0194743 0,15604844 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,0194743 0,1553729 ! social behavior GO:0035176 5 5 0,000 0,0194743 0,15470319 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,0194743 0,15403923 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,0194743 0,15338094 ! memory GO:0007613 5 5 0,000 0,0194743 0,15272826 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,0194743 0,1520811 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,0194743 0,15143941 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,0194743 0,15080311 ! response to lipid GO:0033993 5 5 0,000 0,0194743 0,15017214 ! erythrocyte maturation GO:0043249 5 5 0,000 0,0194743 0,14954642 ! hippocampus development GO:0021766 6 5 0,000 0,0194743 0,1489259 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,0194743 0,1483105 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,0194743 0,14770017 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,0194743 0,14709484 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,0194743 0,14649445 ! mechanosensory behavior GO:0007638 5 5 0,000 0,0194743 0,14589895 ! heart looping GO:0001947 5 5 0,000 0,0194743 0,14530826 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,0194743 0,14472234 ! response to interferon-gamma GO:0034341 5 5 0,000 0,0194743 0,14414113 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,0194743 0,14356456 ! endocrine pancreas development GO:0031018 5 5 0,000 0,0194743 0,14299259 ! pH reduction GO:0045851 5 5 0,000 0,0194743 0,14242516 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,0194743 0,14186222 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,0194743 0,1413037 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,0194743 0,14074957 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,0194743 0,14019977 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,0194743 0,13965424 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,0194743 0,13911295 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,0194743 0,13857583 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,0194743 0,13804285 ! adrenal gland development GO:0030325 5 5 0,000 0,0194743 0,13751395 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,0194743 0,13698909 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,0194743 0,13646822 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,0194743 0,13595129 ! astrocyte differentiation GO:0048708 5 5 0,000 0,0194743 0,13543827 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,0194743 0,1349291 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,0194743 0,13442375 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,0194743 0,13392217 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,0194743 0,13342431 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,0194743 0,13293015 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,0194743 0,13243963 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,0194743 0,13195272 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,0194743 0,13146938 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,0194743 0,13098956 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,0194743 0,13051324 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,0194743 0,13004036 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,0194743 0,12957091 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,0194743 0,12910482 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,0194743 0,12864208 ! response to ATP GO:0033198 5 5 0,000 0,0194743 0,12818265 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,0194743 0,12772648 ! regulation of appetite GO:0032098 5 5 0,000 0,0194743 0,12727355 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,0194743 0,12682382 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,0194743 0,12637726 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,0194743 0,12593383 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,0194743 0,1254935 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,0194743 0,12505624 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0194743 0,12462202 ! receptor clustering GO:0043113 5 5 0,000 0,0194743 0,1241908 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,0194743 0,12376255 ! fear response GO:0042596 5 5 0,000 0,0194743 0,12333725 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,0194743 0,12291487 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,0194743 0,12249536 ! retinol metabolic process GO:0042572 5 5 0,000 0,0194743 0,12207871 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,0194743 0,12166488 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,0194743 0,12125385 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,0194743 0,12084559 ! parturition GO:0007567 5 5 0,000 0,0194743 0,12044007 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0194743 0,12003726 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,0194743 0,11963714 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,0194743 0,11923967 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,0194743 0,11884484 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,0194743 0,11845261 ! protein heterooligomerization GO:0051291 5 5 0,000 0,0194743 0,11806296 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,0194743 0,11767587 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,0194743 0,11729131 ! response to UV-B GO:0010224 5 5 0,000 0,0194743 0,11690925 ! oligodendrocyte development GO:0014003 5 5 0,000 0,0194743 0,11652968 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,0194743 0,11615256 ! activated T cell proliferation GO:0050798 5 5 0,000 0,0194743 0,11577787 ! cellular extravasation GO:0045123 5 5 0,000 0,0194743 0,1154056 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,0194743 0,11503571 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,0194743 0,11466818 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,0194743 0,114303 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,0194743 0,11394013 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,0194743 0,11357956 ! response to amine stimulus GO:0014075 5 5 0,000 0,0194743 0,11322126 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,0194743 0,11286522 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,0194743 0,11251141 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,0194743 0,11215981 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,0194743 0,11181041 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,0194743 0,11146317 ! neuron recognition GO:0008038 5 5 0,000 0,0194743 0,11111808 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,0194743 0,11077513 ! decidualization GO:0046697 5 5 0,000 0,0194743 0,11043428 ! hair follicle maturation GO:0048820 5 5 0,000 0,0194743 0,11009552 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,0194743 0,10975884 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,0194743 0,10942421 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,0194743 0,10909161 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,0194743 0,10876103 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,0194743 0,10843245 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,0194743 0,10810585 ! postreplication repair GO:0006301 5 5 0,000 0,0194743 0,1077812 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,0194743 0,10745851 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,0194743 0,10713773 ! histone methylation GO:0016571 5 5 0,000 0,0194743 0,10681887 ! DNA methylation GO:0006306 5 5 0,000 0,0194743 0,1065019 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0194743 0,10618681 ! T cell lineage commitment GO:0002360 5 5 0,000 0,0194743 0,10587357 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,0194743 0,10556218 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,0194743 0,10525261 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,0194743 0,10494486 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,0194743 0,10463889 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,0194743 0,10433471 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,0194743 0,10403229 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,0194743 0,10373162 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,0194743 0,10343268 ! sterol catabolic process GO:0016127 5 5 0,000 0,0194743 0,10313546 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,0194743 0,10283994 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,0194743 0,10254612 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,0194743 0,10225396 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,0194743 0,10196347 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! zymogen activation GO:0031638 5 5 0,000 0,0194743 0,10167462 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,0194743 0,1013874 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,0194743 0,1011018 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,0194743 0,10081781 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,0194743 0,10053541 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,0194743 0,10025458 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,0194743 0,09997532 ! nucleosome positioning GO:0016584 5 5 0,000 0,0194743 0,09969761 ! regulation of isotype switching GO:0045191 5 5 0,000 0,0194743 0,09942144 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,0194743 0,0991468 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,0194743 0,09887367 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,0194743 0,09860203 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,0194743 0,09833189 ! NADPH regeneration GO:0006740 5 5 0,000 0,0194743 0,09806323 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,0194743 0,09779602 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,0194743 0,09753027 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,0194743 0,09726596 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,0194743 0,09700308 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,0194743 0,09674162 ! sarcomere organization GO:0045214 5 5 0,000 0,0194743 0,09648156 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,0194743 0,0962229 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,0194743 0,09596562 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,0194743 0,09570971 GO:0046325|negative regulation of glucose import, ! oocyte differentiation GO:0009994 5 5 0,000 0,0194743 0,09545516 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,0194743 0,09520196 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,0194743 0,09495011 ! spleen development GO:0048536 5 5 0,000 0,0194743 0,09469958 ! male genitalia development GO:0030539 5 5 0,000 0,0194743 0,09445037 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,0194743 0,09420247 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,0194743 0,09395587 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,0194743 0,09371055 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,0194743 0,09346651 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,0194743 0,09322374 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,0194743 0,09298223 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,0194743 0,09274197 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,0194743 0,09250294 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,0194743 0,09226514 ! ATP catabolic process GO:0006200 5 5 0,000 0,0194743 0,09202857 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0194743 0,0917932 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,0194743 0,09155903 ! blastocyst formation GO:0001825 5 5 0,000 0,0194743 0,09132606 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,0194743 0,09109427 ! embryonic gut development GO:0048566 5 5 0,000 0,0194743 0,09086365 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,0194743 0,09063419 ! activation of innate immune response GO:0002218 5 5 0,000 0,0194743 0,0904059 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,0194743 0,09017875 ! catecholamine transport GO:0051937 5 5 0,000 0,0194743 0,08995273 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,0194743 0,08972785 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,0194743 0,08950409 ! muscle adaptation GO:0043500 5 5 0,000 0,0194743 0,08928144 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,0194743 0,0890599 ! embryonic heart tube development GO:0035050 5 5 0,000 0,0194743 0,08883946 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,0194743 0,0886201 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,0194743 0,08840182 ! defense response to fungus GO:0050832 5 5 0,000 0,0194743 0,08818462 ! lysogeny GO:0030069 5 5 0,000 0,0194743 0,08796848 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,0194743 0,0877534 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,0194743 0,08753937 ! response to nicotine GO:0035094 5 5 0,000 0,0194743 0,08732638 ! establishment of cell polarity GO:0030010 5 5 0,000 0,0194743 0,08711442 ! nucleus localization GO:0051647 5 5 0,000 0,0194743 0,08690349 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,0194743 0,08669358 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 1,000 0,02005156 0,08904824 ! regulation of nervous system development GO:0051960 57 56 1,000 0,02005156 0,08883418 ! regulation of binding GO:0051098 60 57 1,000 0,0207309 0,09162361 ! ATP metabolic process GO:0046034 57 57 1,000 0,0207309 0,09140442 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 1,000 0,0207309 0,09118627 ! carboxylic acid transport GO:0046942 59 59 1,000 0,0221183 0,09705719 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 1,000 0,0221183 0,09682665 ! regulation of cell development GO:0060284 60 59 1,000 0,0221183 0,0965972 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,0221183 0,09636884 ! immune effector process GO:0002252 59 59 1,000 0,0221183 0,09614155 ! protein polymerization GO:0051258 65 60 1,000 0,02282619 0,0989851 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02332509 0,10091115 ! axon extension GO:0048675 7 6 0,000 0,02332509 0,10067482 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02332509 0,1004396 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,02332509 0,10020548 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,02332509 0,09997244 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02332509 0,09974049 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02332509 0,09950961 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02332509 0,09927979 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02332509 0,09905104 ! virus-host interaction GO:0019048 6 6 0,000 0,02332509 0,09882333 ! regulation of S phase GO:0033261 6 6 0,000 0,02332509 0,09859667 ! myotube differentiation GO:0014902 6 6 0,000 0,02332509 0,09837105 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02332509 0,09814646 ! bone remodeling GO:0046849 6 6 0,000 0,02332509 0,09792289 ! N-glycan processing GO:0006491 6 6 0,000 0,02332509 0,09770034 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02332509 0,0974788 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02332509 0,09725826 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02332509 0,09703871 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02332509 0,09682016 ! RNA methylation GO:0001510 6 6 0,000 0,02332509 0,09660258 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02332509 0,09638599 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02332509 0,09617036 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02332509 0,09595569 ! artery development GO:0060840 6 6 0,000 0,02332509 0,09574198 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02332509 0,09552922 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02332509 0,09531741 ! androgen metabolic process GO:0008209 6 6 0,000 0,02332509 0,09510653 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02332509 0,09489658 ! limbic system development GO:0021761 7 6 0,000 0,02332509 0,09468756 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02332509 0,09447945 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,02332509 0,09427226 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02332509 0,09406597 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02332509 0,09386059 ! pathogenesis GO:0009405 6 6 0,000 0,02332509 0,0936561 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02332509 0,0934525 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02332509 0,09324978 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02332509 0,09304794 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02332509 0,09284698 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02332509 0,09264688 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02332509 0,09244763 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02332509 0,09224925 ! arginine metabolic process GO:0006525 6 6 0,000 0,02332509 0,09205171 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02332509 0,09185502 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02332509 0,09165917 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02332509 0,09146415 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02332509 0,09126996 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02332509 0,09107659 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02332509 0,09088404 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02332509 0,0906923 ! ER overload response GO:0006983 6 6 0,000 0,02332509 0,09050137 ! V(D)J recombination GO:0033151 6 6 0,000 0,02332509 0,09031124 ! focal adhesion formation GO:0048041 7 6 0,000 0,02332509 0,09012191 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02332509 0,08993337 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,02332509 0,08974562 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02332509 0,08955865 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02332509 0,08937245 ! regulation of heart rate GO:0002027 6 6 0,000 0,02332509 0,08918703 ! lipid digestion GO:0044241 6 6 0,000 0,02332509 0,08900238 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02332509 0,08881849 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02332509 0,08863536 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02332509 0,08845298 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02332509 0,08827136 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02332509 0,08809047 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02332509 0,08791033 ! ruffle organization GO:0031529 6 6 0,000 0,02332509 0,08773092 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02332509 0,08755224 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02332509 0,08737429 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02332509 0,08719706 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02332509 0,08702055 ! L-amino acid transport GO:0015807 6 6 0,000 0,02332509 0,08684475 ! bone mineralization GO:0030282 6 6 0,000 0,02332509 0,08666966 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02332509 0,08649527 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02332509 0,08632159 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02332509 0,0861486 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02332509 0,0859763 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02332509 0,08580469 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02332509 0,08563377 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,02332509 0,08546352 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02332509 0,08529395 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02332509 0,08512505 ! regulation of organ growth GO:0046620 6 6 0,000 0,02332509 0,08495682 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02332509 0,08478925 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02332509 0,08462234 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02332509 0,08445609 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02332509 0,08429049 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,02332509 0,08412554 ! genitalia development GO:0048806 6 6 0,000 0,02332509 0,08396123 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02332509 0,08379756 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02332509 0,08363453 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,02332509 0,08347214 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02332509 0,08331037 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02332509 0,08314923 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02332509 0,08298871 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02332509 0,08282881 ! erythrocyte development GO:0048821 6 6 0,000 0,02332509 0,08266952 ! renal water homeostasis GO:0003091 6 6 0,000 0,02332509 0,08251084 ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02332509 0,08235278 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02332509 0,08219532 ! ribosome assembly GO:0042255 6 6 0,000 0,02332509 0,08203845 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02332509 0,08188219 ! diencephalon development GO:0021536 6 6 0,000 0,02332509 0,08172652 ! fucose catabolic process GO:0019317 6 6 0,000 0,02332509 0,08157144 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02332509 0,08141695 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02332509 0,08126304 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02332509 0,08110972 ! regulation of cell division GO:0051302 6 6 0,000 0,02332509 0,08095697 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02332509 0,08080479 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02332509 0,08065319 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02332509 0,08050215 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02332509 0,08035168 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02332509 0,08020177 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02332509 0,08005242 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02332509 0,07990362 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02332509 0,07975538 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02332509 0,07960769 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02332509 0,07946054 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02332509 0,07931393 ! thymus development GO:0048538 6 6 0,000 0,02332509 0,07916786 ! lymph node development GO:0048535 6 6 0,000 0,02332509 0,07902233 ! organic cation transport GO:0015695 6 6 0,000 0,02332509 0,07887734 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02332509 0,07873288 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02332509 0,07858894 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,02332509 0,07844553 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02332509 0,07830264 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02332509 0,07816027 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02332509 0,07801842 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02332509 0,07787708 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02332509 0,07773626 ! alditol metabolic process GO:0019400 6 6 0,000 0,02332509 0,07759594 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02332509 0,07745613 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02332509 0,07731682 ! maternal placenta development GO:0001893 6 6 0,000 0,02332509 0,07717801 ! regulation of embryonic development GO:0045995 6 6 0,000 0,02332509 0,0770397 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02332509 0,07690188 ! localization within membrane GO:0051668 6 6 0,000 0,02332509 0,07676455 ! cellular respiration GO:0045333 62 61 1,000 0,02354345 0,07734504 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,02354345 0,07720742 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 1,000 0,02426998 0,07944862 ! axonogenesis GO:0007409 66 62 1,000 0,02426998 0,07930776 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,02426998 0,07916739 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 1,000 0,02500572 0,08142321 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 1,000 0,02500572 0,08127961 ! angiogenesis GO:0001525 65 64 1,000 0,02575058 0,08355338 ! anion transport GO:0006820 65 65 1,000 0,02650449 0,08584847 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,02650449 0,08569786 ! respiratory burst GO:0045730 7 7 0,000 0,02716132 0,0876678 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02716132 0,08751454 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02716132 0,08736181 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02716132 0,08720961 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02716132 0,08705794 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,02716132 0,0869068 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02716132 0,08675618 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02716132 0,08660608 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02716132 0,0864565 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02716132 0,08630744 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02716132 0,08615889 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02716132 0,08601085 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,02716132 0,08586332 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02716132 0,08571629 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02716132 0,08556977 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02716132 0,08542375 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02716132 0,08527822 ! axis specification GO:0009798 7 7 0,000 0,02716132 0,08513319 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02716132 0,08498865 ! visual behavior GO:0007632 7 7 0,000 0,02716132 0,0848446 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02716132 0,08470104 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02716132 0,08455797 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02716132 0,08441537 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02716132 0,08427326 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02716132 0,08413162 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02716132 0,08399046 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02716132 0,08384978 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02716132 0,08370956 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02716132 0,08356981 ! digestive system development GO:0055123 7 7 0,000 0,02716132 0,08343053 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02716132 0,08329171 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02716132 0,08315335 ! protein targeting to ER GO:0045047 8 7 0,000 0,02716132 0,08301545 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02716132 0,08287801 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02716132 0,08274102 ! endoderm development GO:0007492 7 7 0,000 0,02716132 0,08260448 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02716132 0,0824684 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02716132 0,08233276 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,02716132 0,08219756 ! response to hexose stimulus GO:0009746 7 7 0,000 0,02716132 0,08206281 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02716132 0,0819285 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02716132 0,08179463 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02716132 0,0816612 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,02716132 0,0815282 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02716132 0,08139564 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02716132 0,0812635 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02716132 0,08113179 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02716132 0,08100051 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02716132 0,08086965 ! response to X-ray GO:0010165 7 7 0,000 0,02716132 0,08073922 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,02716132 0,0806092 ! UV protection GO:0009650 7 7 0,000 0,02716132 0,08047961 ! DNA integration GO:0015074 7 7 0,000 0,02716132 0,08035043 ! myofibril assembly GO:0030239 7 7 0,000 0,02716132 0,08022166 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,02716132 0,08009331 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02716132 0,07996536 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02716132 0,07983782 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02716132 0,07971069 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02716132 0,07958397 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02716132 0,07945764 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02716132 0,07933172 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02716132 0,0792062 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02716132 0,07908107 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02716132 0,07895633 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02716132 0,07883199 ! axon cargo transport GO:0008088 7 7 0,000 0,02716132 0,07870804 ! eating behavior GO:0042755 7 7 0,000 0,02716132 0,07858448 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02716132 0,07846131 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02716132 0,07833852 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02716132 0,07821612 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02716132 0,0780941 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02716132 0,07797245 ! cranial nerve development GO:0021545 7 7 0,000 0,02716132 0,07785119 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02716132 0,0777303 ! induction of an organ GO:0001759 7 7 0,000 0,02716132 0,07760979 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02716132 0,07748965 GO:0002263|cell activation during immune response, ! autonomic nervous system development GO:0048483 7 7 0,000 0,02716132 0,07736989 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02716132 0,07725049 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02716132 0,07713146 ! platelet activation GO:0030168 8 7 0,000 0,02716132 0,07701279 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02716132 0,07689449 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02716132 0,07677656 ! natural killer cell activation GO:0030101 7 7 0,000 0,02716132 0,07665898 ! response to gamma radiation GO:0010332 8 7 0,000 0,02716132 0,07654177 ! NADP metabolic process GO:0006739 7 7 0,000 0,02716132 0,07642491 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02716132 0,07630841 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02716132 0,07619226 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02716132 0,07607647 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02716132 0,07596103 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02716132 0,07584593 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02716132 0,07573119 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02716132 0,07561679 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02716132 0,07550274 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02716132 0,07538903 ! cell-cell recognition GO:0009988 8 7 0,000 0,02716132 0,07527566 ! hormone catabolic process GO:0042447 7 7 0,000 0,02716132 0,07516264 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02716132 0,07504995 ! oxygen transport GO:0015671 7 7 0,000 0,02716132 0,0749376 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02716132 0,07482558 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,02716132 0,0747139 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02716132 0,07460256 ! regulation of axon extension GO:0030516 7 7 0,000 0,02716132 0,07449154 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02716132 0,07438086 ! adult feeding behavior GO:0008343 7 7 0,000 0,02716132 0,0742705 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02716132 0,07416047 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02716132 0,07405076 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,02716132 0,07394138 ! response to cold GO:0009409 7 7 0,000 0,02716132 0,07383232 ! nucleoside triphosphate metabolic process GO:0009141 66 66 1,000 0,02726737 0,07401145 ! regulation of MAP kinase activity GO:0043405 67 66 1,000 0,02726737 0,0739026 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,02803915 0,07588275 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,02803915 0,07577149 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 1,000 0,02881975 0,0777669 ! regulation of translation GO:0006417 69 69 1,000 0,02960908 0,07978003 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,02960908 0,07966357 ! cell part morphogenesis GO:0032990 75 70 1,000 0,03040709 0,08169135 ! wound healing GO:0042060 74 70 1,000 0,03040709 0,08157244 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,03098304 0,08299671 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,03098304 0,08287625 ! positive regulation of translation GO:0045727 8 8 0,000 0,03098304 0,08275614 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,03098304 0,08263638 ! superoxide anion generation GO:0042554 8 8 0,000 0,03098304 0,08251696 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,03098304 0,08239789 ! cGMP metabolic process GO:0046068 8 8 0,000 0,03098304 0,08227916 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,03098304 0,08216077 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,03098304 0,08204272 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,03098304 0,08192502 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,03098304 0,08180764 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,03098304 0,08169061 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,03098304 0,08157391 ! zinc ion transport GO:0006829 8 8 0,000 0,03098304 0,08145754 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,03098304 0,0813415 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,03098304 0,0812258 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,03098304 0,08111042 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,03098304 0,08099537 ! lipid localization GO:0010876 8 8 0,000 0,03098304 0,08088065 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,03098304 0,08076625 ! response to cAMP GO:0051591 8 8 0,000 0,03098304 0,08065217 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,03098304 0,08053841 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,03098304 0,08042498 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,03098304 0,08031186 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,03098304 0,08019907 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,03098304 0,08008659 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,03098304 0,07997442 ! sensory perception of taste GO:0050909 8 8 0,000 0,03098304 0,07986257 ! organelle fusion GO:0048284 8 8 0,000 0,03098304 0,07975103 ! pancreas development GO:0031016 8 8 0,000 0,03098304 0,0796398 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,03098304 0,07952888 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,03098304 0,07941827 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,03098304 0,07930797 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,03098304 0,07919797 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,03098304 0,07908828 ! sperm motility GO:0030317 8 8 0,000 0,03098304 0,07897889 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,03098304 0,0788698 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,03098304 0,07876101 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,03098304 0,07865253 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,03098304 0,07854434 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,03098304 0,07843645 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,03098304 0,07832886 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,03098304 0,07822156 ! Golgi organization GO:0007030 8 8 0,000 0,03098304 0,07811455 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,03098304 0,07800784 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,03098304 0,07790141 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,03098304 0,07779528 ! fructose metabolic process GO:0006000 8 8 0,000 0,03098304 0,07768944 ! mannose metabolic process GO:0006013 9 8 0,000 0,03098304 0,07758388 ! NAD metabolic process GO:0019674 8 8 0,000 0,03098304 0,07747861 ! sex determination GO:0007530 8 8 0,000 0,03098304 0,07737363 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,03098304 0,07726893 ! plasma membrane fusion GO:0045026 8 8 0,000 0,03098304 0,07716451 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,03098304 0,07706037 ! response to fungus GO:0009620 8 8 0,000 0,03098304 0,07695652 ! stem cell differentiation GO:0048863 8 8 0,000 0,03098304 0,07685294 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,03098304 0,07674964 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,03098304 0,07664663 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,03098304 0,07654388 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,03098304 0,07644141 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,03098304 0,07633922 ! regulation of vasodilation GO:0042312 8 8 0,000 0,03098304 0,0762373 ! vasoconstriction GO:0042310 8 8 0,000 0,03098304 0,07613565 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,03098304 0,07603427 ! muscle cell development GO:0055001 8 8 0,000 0,03098304 0,07593316 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,03098304 0,07583232 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,03098304 0,07573175 ! sensory perception of pain GO:0019233 8 8 0,000 0,03098304 0,07563144 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,03098304 0,0755314 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,03098304 0,07543162 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,03098304 0,07533211 ! chromatin silencing GO:0006342 8 8 0,000 0,03098304 0,07523285 ! tissue regeneration GO:0042246 8 8 0,000 0,03098304 0,07513386 ! salivary gland development GO:0007431 8 8 0,000 0,03098304 0,07503513 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,03098304 0,07493666 ! T cell homeostasis GO:0043029 8 8 0,000 0,03098304 0,07483845 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,03098304 0,07474049 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,03098304 0,07464279 ! water homeostasis GO:0030104 8 8 0,000 0,03098304 0,07454535 ! cofactor transport GO:0051181 8 8 0,000 0,03098304 0,07444816 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,03098304 0,07435122 ! acid secretion GO:0046717 8 8 0,000 0,03098304 0,07425453 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,03098304 0,0741581 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,03098304 0,07406191 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,03098304 0,07396598 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,03098304 0,07387029 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,03098304 0,07377485 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,03098304 0,07367966 ! regulation of RNA stability GO:0043487 8 8 0,000 0,03098304 0,07358471 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,03098304 0,07349001 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,03098304 0,07339555 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,03098304 0,07330133 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,03098304 0,07320735 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,03098304 0,07311362 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,03098304 0,07302012 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,03098304 0,07292687 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,03098304 0,07283385 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,03098304 0,07274106 ! developmental induction GO:0031128 8 8 0,000 0,03098304 0,07264852 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,03098304 0,07255621 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,03098304 0,07246413 ! actin filament polymerization GO:0030041 9 8 0,000 0,03098304 0,07237229 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,03098304 0,07228068 ! peptide hormone processing GO:0016486 8 8 0,000 0,03098304 0,0721893 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,03098304 0,07209815 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,03098304 0,07200723 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,03121369 0,07245193 ! regulation of cell activation GO:0050865 71 71 1,000 0,03121369 0,07236079 ! regulation of cytokine production GO:0001817 72 72 1,000 0,03202881 0,07415716 ! electron transport chain GO:0022900 75 74 1,000 0,03368431 0,07789232 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,03452454 0,07973525 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,03452454 0,07963546 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03479029 0,08014813 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03479029 0,08004807 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03479029 0,07994826 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03479029 0,0798487 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03479029 0,07974939 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03479029 0,07965032 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,03479029 0,0795515 ! viral genome replication GO:0019079 9 9 0,000 0,03479029 0,07945292 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03479029 0,07935459 ! copper ion transport GO:0006825 9 9 0,000 0,03479029 0,0792565 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03479029 0,07915865 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03479029 0,07906104 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03479029 0,07896368 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03479029 0,07886655 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03479029 0,07876966 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03479029 0,07867302 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03479029 0,0785766 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03479029 0,07848043 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03479029 0,07838448 ! phospholipid efflux GO:0033700 9 9 0,000 0,03479029 0,07828878 ! response to alkaloid GO:0043279 10 9 0,000 0,03479029 0,0781933 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03479029 0,07809806 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03479029 0,07800305 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03479029 0,07790827 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03479029 0,07781372 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03479029 0,0777194 ! response to ethanol GO:0045471 9 9 0,000 0,03479029 0,07762531 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,03479029 0,07753145 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03479029 0,07743781 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03479029 0,0773444 ! methionine metabolic process GO:0006555 9 9 0,000 0,03479029 0,07725121 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03479029 0,07715825 ! cerebral cortex development GO:0021987 9 9 0,000 0,03479029 0,07706551 ! response to osmotic stress GO:0006970 9 9 0,000 0,03479029 0,076973 ! pigmentation during development GO:0048066 9 9 0,000 0,03479029 0,0768807 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03479029 0,07678863 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03479029 0,07669678 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03479029 0,07660515 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03479029 0,07651373 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03479029 0,07642254 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03479029 0,07633156 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03479029 0,07624079 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03479029 0,07615025 GO:0060675|ureteric bud morphogenesis, ! peptide secretion GO:0002790 9 9 0,000 0,03479029 0,07605991 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03479029 0,0759698 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03479029 0,07587989 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03479029 0,0757902 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03479029 0,07570072 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03479029 0,07561145 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,03479029 0,07552239 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03479029 0,07543354 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03479029 0,0753449 ! regulation of cellular pH GO:0030641 9 9 0,000 0,03479029 0,07525646 ! histone acetylation GO:0016573 9 9 0,000 0,03479029 0,07516824 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03479029 0,07508022 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03479029 0,07499241 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03479029 0,0749048 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03479029 0,07481739 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03479029 0,07473019 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03479029 0,0746432 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,03479029 0,0745564 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03479029 0,07446981 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03479029 0,07438342 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03479029 0,07429723 ! collagen catabolic process GO:0030574 9 9 0,000 0,03479029 0,07421124 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03479029 0,07412544 ! purine base metabolic process GO:0006144 9 9 0,000 0,03479029 0,07403985 ! gas transport GO:0015669 9 9 0,000 0,03479029 0,07395445 ! cholesterol efflux GO:0033344 9 9 0,000 0,03479029 0,07386925 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03479029 0,07378424 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03479029 0,07369943 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03479029 0,07361482 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03479029 0,0735304 ! defense response to virus GO:0051607 9 9 0,000 0,03479029 0,07344617 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03479029 0,07336214 ! actin filament-based movement GO:0030048 9 9 0,000 0,03479029 0,07327829 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03479029 0,07319464 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,035373 0,07433574 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,035373 0,07425108 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,03622962 0,07596267 ! regulation of protein modification process GO:0031399 79 78 1,000 0,03709431 0,07768729 ! microtubule-based movement GO:0007018 82 78 1,000 0,03709431 0,07759911 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03858314 0,08062214 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03858314 0,08053083 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03858314 0,08043974 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03858314 0,08034884 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,03858314 0,08025816 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03858314 0,08016767 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03858314 0,0800774 ! neuron maturation GO:0042551 10 10 0,000 0,03858314 0,07998732 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03858314 0,07989745 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03858314 0,07980777 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03858314 0,0797183 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03858314 0,07962903 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03858314 0,07953996 ! hormone secretion GO:0046879 10 10 0,000 0,03858314 0,07945109 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03858314 0,07936242 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03858314 0,07927394 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,03858314 0,07918566 ! inositol metabolic process GO:0006020 10 10 0,000 0,03858314 0,07909758 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03858314 0,0790097 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03858314 0,07892201 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03858314 0,07883451 ! glial cell development GO:0021782 10 10 0,000 0,03858314 0,07874721 ! phototransduction GO:0007602 11 10 0,000 0,03858314 0,0786601 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03858314 0,07857318 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03858314 0,07848645 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,03858314 0,07839992 ! fat cell differentiation GO:0045444 10 10 0,000 0,03858314 0,07831358 ! myoblast differentiation GO:0045445 10 10 0,000 0,03858314 0,07822742 ! centrosome cycle GO:0007098 10 10 0,000 0,03858314 0,07814146 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03858314 0,07805568 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03858314 0,0779701 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03858314 0,0778847 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03858314 0,07779948 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03858314 0,07771446 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03858314 0,07762961 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03858314 0,07754496 ! plasma membrane organization GO:0007009 10 10 0,000 0,03858314 0,07746049 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03858314 0,0773762 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,03858314 0,07729209 ! lysosomal transport GO:0007041 10 10 0,000 0,03858314 0,07720817 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03858314 0,07712443 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03858314 0,07704087 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03858314 0,0769575 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03858314 0,0768743 ! exocrine system development GO:0035272 10 10 0,000 0,03858314 0,07679128 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03858314 0,07670844 ! neuromuscular junction development GO:0007528 10 10 0,000 0,03858314 0,07662578 ! regulation of protein binding GO:0043393 11 10 0,000 0,03858314 0,0765433 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03858314 0,076461 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03858314 0,07637887 GO:0070585|protein localization in mitochondrion, ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03858314 0,07629692 ! protein export from nucleus GO:0006611 10 10 0,000 0,03858314 0,07621514 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03858314 0,07613354 ! cytolysis GO:0019835 10 10 0,000 0,03858314 0,07605211 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03858314 0,07597086 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03858314 0,07588978 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03858314 0,07580888 ! histone deacetylation GO:0016575 10 10 0,000 0,03858314 0,07572814 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03858314 0,07564758 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03858314 0,07556719 ! gland morphogenesis GO:0022612 10 10 0,000 0,03858314 0,07548697 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03858314 0,07540692 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03858314 0,07532704 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03858314 0,07524733 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03858314 0,07516779 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,03858314 0,07508841 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03858314 0,07500921 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03858314 0,07493017 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03858314 0,07485129 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03858314 0,07477258 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03858314 0,07469404 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03858314 0,07461566 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,03858314 0,07453745 ! gut development GO:0048565 10 10 0,000 0,03858314 0,0744594 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03858314 0,07438151 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,03858314 0,07430379 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,03858314 0,07422623 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03858314 0,07414883 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03858314 0,07407159 ! neuron projection development GO:0031175 85 80 1,000 0,03884766 0,07450182 ! tube development GO:0035295 83 81 1,000 0,03973618 0,07612659 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,04153653 0,07949308 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,04153653 0,07941061 ! protein secretion GO:0009306 11 11 0,000 0,04236163 0,08090414 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04236163 0,08082038 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04236163 0,08073681 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04236163 0,0806534 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04236163 0,08057017 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04236163 0,08048711 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04236163 0,08040421 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04236163 0,08032149 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04236163 0,08023894 ! signal complex assembly GO:0007172 11 11 0,000 0,04236163 0,08015656 ! microtubule-based transport GO:0010970 11 11 0,000 0,04236163 0,08007435 ! endothelial cell migration GO:0043542 11 11 0,000 0,04236163 0,07999231 ! peroxisomal transport GO:0043574 11 11 0,000 0,04236163 0,07991043 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04236163 0,07982872 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,04236163 0,07974718 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,04236163 0,07966581 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,04236163 0,0795846 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04236163 0,07950356 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04236163 0,07942268 ! T cell proliferation GO:0042098 11 11 0,000 0,04236163 0,07934196 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04236163 0,07926141 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04236163 0,07918103 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04236163 0,0791008 ! spinal cord development GO:0021510 11 11 0,000 0,04236163 0,07902074 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,04236163 0,07894084 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04236163 0,0788611 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,04236163 0,07878153 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04236163 0,07870211 ! digestive system process GO:0022600 11 11 0,000 0,04236163 0,07862285 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04236163 0,07854375 ! fucose metabolic process GO:0006004 11 11 0,000 0,04236163 0,07846482 ! membrane budding GO:0006900 11 11 0,000 0,04236163 0,07838604 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04236163 0,07830741 ! monoamine transport GO:0015844 11 11 0,000 0,04236163 0,07822895 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04236163 0,07815064 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,04236163 0,07807249 ! body fluid secretion GO:0007589 11 11 0,000 0,04236163 0,0779945 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,04236163 0,07791666 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04236163 0,07783897 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04236163 0,07776145 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,04236163 0,07768407 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04236163 0,07760685 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04236163 0,07752978 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,04236163 0,07745287 ! oogenesis GO:0048477 11 11 0,000 0,04236163 0,07737611 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04236163 0,0772995 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04236163 0,07722304 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,04236163 0,07714673 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,04236163 0,07707057 ! muscle maintenance GO:0046716 12 11 0,000 0,04236163 0,07699457 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04236163 0,07691871 ! hindbrain development GO:0030902 11 11 0,000 0,04236163 0,076843 ! steroid catabolic process GO:0006706 11 11 0,000 0,04236163 0,07676745 ! endocrine process GO:0050886 11 11 0,000 0,04236163 0,07669204 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04236163 0,07661677 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04236163 0,07654166 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04236163 0,07646669 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04236163 0,07639187 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,04236163 0,0763172 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,04336753 0,07805308 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,04612583 0,08293649 ! translational initiation GO:0006413 12 12 0,000 0,04612583 0,08285565 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,04612583 0,08277497 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,04612583 0,08269445 ! initiation of viral infection GO:0019059 12 12 0,000 0,04612583 0,08261409 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04612583 0,08253388 ! iron ion transport GO:0006826 13 12 0,000 0,04612583 0,08245383 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04612583 0,08237393 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04612583 0,08229419 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04612583 0,0822146 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,04612583 0,08213517 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,04612583 0,08205589 ! collagen metabolic process GO:0032963 12 12 0,000 0,04612583 0,08197676 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04612583 0,08189778 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04612583 0,08181896 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04612583 0,08174029 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04612583 0,08166177 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04612583 0,0815834 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04612583 0,08150518 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,04612583 0,08142711 ! actomyosin structure organization GO:0031032 12 12 0,000 0,04612583 0,08134918 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,04612583 0,08127141 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,04612583 0,08119379 ! retinoid metabolic process GO:0001523 12 12 0,000 0,04612583 0,08111631 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04612583 0,08103899 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04612583 0,08096181 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04612583 0,08088477 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,04612583 0,08080789 ! acute-phase response GO:0006953 12 12 0,000 0,04612583 0,08073115 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04612583 0,08065455 ! vacuolar transport GO:0007034 12 12 0,000 0,04612583 0,0805781 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04612583 0,0805018 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04612583 0,08042564 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04612583 0,08034962 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04612583 0,08027375 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,04612583 0,08019802 ! male gonad development GO:0008584 12 12 0,000 0,04612583 0,08012243 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04612583 0,08004698 ! renal system process GO:0003014 12 12 0,000 0,04612583 0,07997168 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04612583 0,07989652 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,04612583 0,0798215 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04612583 0,07974662 ! pallium development GO:0021543 13 12 0,000 0,04612583 0,07967188 ! cell fate determination GO:0001709 12 12 0,000 0,04612583 0,07959728 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,04612583 0,07952282 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04612583 0,0794485 ! somitogenesis GO:0001756 13 12 0,000 0,04612583 0,07937432 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04612583 0,07930028 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04612583 0,07922637 ! detection of light stimulus GO:0009583 13 12 0,000 0,04612583 0,07915261 ! synaptogenesis GO:0007416 12 12 0,000 0,04612583 0,07907897 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04612583 0,07900548 ! hormone transport GO:0009914 12 12 0,000 0,04612583 0,07893212 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04612583 0,0788589 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04612583 0,07878582 ! spermatid differentiation GO:0048515 13 12 0,000 0,04612583 0,07871287 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04612583 0,07864005 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04612583 0,07856737 ! neural tube closure GO:0001843 13 12 0,000 0,04612583 0,07849483 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,04612583 0,07842242 ! negative regulation of translation GO:0017148 12 12 0,000 0,04612583 0,07835014 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04612583 0,07827799 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,04612583 0,07820598 ! chemotaxis GO:0006935 90 89 1,000 0,04711922 0,07981684 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,04807544 0,08136183 ! DNA replication GO:0006260 91 91 1,000 0,04903884 0,08291614 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,04987577 0,08425393 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,04987577 0,08417678 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04987577 0,08409976 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04987577 0,08402289 ! phenol metabolic process GO:0018958 13 13 0,000 0,04987577 0,08394616 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,04987577 0,08386956 ! gluconeogenesis GO:0006094 13 13 0,000 0,04987577 0,08379311 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,04987577 0,0837168 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04987577 0,08364062 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04987577 0,08356458 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04987577 0,08348868 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,04987577 0,08341292 ! regeneration GO:0031099 13 13 0,000 0,04987577 0,0833373 ! keratinization GO:0031424 13 13 0,000 0,04987577 0,08326181 ! post-embryonic development GO:0009791 14 13 0,000 0,04987577 0,08318646 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04987577 0,08311125 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04987577 0,08303617 ! vasculogenesis GO:0001570 13 13 0,000 0,04987577 0,08296123 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04987577 0,08288642 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04987577 0,08281175 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,04987577 0,08273721 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,04987577 0,08266281 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04987577 0,08258854 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04987577 0,0825144 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04987577 0,0824404 ! autophagy GO:0006914 13 13 0,000 0,04987577 0,08236652 ! receptor metabolic process GO:0043112 14 13 0,000 0,04987577 0,08229279 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04987577 0,08221918 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,04987577 0,0821457 ! ureteric bud development GO:0001657 13 13 0,000 0,04987577 0,08207236 ! cell aging GO:0007569 13 13 0,000 0,04987577 0,08199914 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,04987577 0,08192606 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,04987577 0,08185311 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,04987577 0,08178029 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04987577 0,08170759 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04987577 0,08163503 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04987577 0,08156259 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04987577 0,08149028 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04987577 0,08141811 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04987577 0,08134605 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04987577 0,08127413 ! vasodilation GO:0042311 14 13 0,000 0,04987577 0,08120233 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04987577 0,08113066 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04987577 0,08105912 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04987577 0,0809877 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,04987577 0,08091641 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,04987577 0,08084524 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04987577 0,0807742 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04987577 0,08070328 ! immunoglobulin production GO:0002377 13 13 0,000 0,04987577 0,08063249 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04987577 0,08056182 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,04987577 0,08049128 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,04987577 0,08042086 ! cell-cell junction organization GO:0045216 13 13 0,000 0,04987577 0,08035056 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,04987577 0,08028039 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04987577 0,08021033 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04987577 0,0801404 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04987577 0,08007059 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04987577 0,08000091 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04987577 0,07993134 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04987577 0,0798619 GO:0033014|tetrapyrrole biosynthetic process, ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04987577 0,07979257 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04987577 0,07972337 ! blastocyst development GO:0001824 13 13 0,000 0,04987577 0,07965428 ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04987577 0,07958532 ! regulation of amine transport GO:0051952 13 13 0,000 0,04987577 0,07951647 ! tissue homeostasis GO:0001894 13 13 0,000 0,04987577 0,07944775 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04987577 0,07937914 ! protein tetramerization GO:0051262 13 13 0,000 0,04987577 0,07931065 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,05000936 0,07945453 ! tissue morphogenesis GO:0048729 94 93 1,000 0,05098694 0,08093792 ! regulation of response to stress GO:0080134 97 94 1,000 0,05197149 0,08242983 ! blood vessel development GO:0001568 95 94 1,000 0,05197149 0,08235895 ! neuron fate commitment GO:0048663 14 14 0,000 0,05361151 0,08488489 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,05361151 0,08481203 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,05361151 0,08473929 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,05361151 0,08466668 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,05361151 0,08459419 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,05361151 0,08452183 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,05361151 0,08444959 ! protein amino acid acylation GO:0043543 14 14 0,000 0,05361151 0,08437747 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,05361151 0,08430548 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,05361151 0,0842336 ! vesicle docking GO:0048278 14 14 0,000 0,05361151 0,08416185 ! superoxide metabolic process GO:0006801 15 14 0,000 0,05361151 0,08409023 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,05361151 0,08401872 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,05361151 0,08394734 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,05361151 0,08387608 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,05361151 0,08380493 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,05361151 0,08373391 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,05361151 0,08366301 ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,05361151 0,08359223 ! lysosome organization GO:0007040 14 14 0,000 0,05361151 0,08352157 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,05361151 0,08345103 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,05361151 0,08338061 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,05361151 0,0833103 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,05361151 0,08324012 ! primary neural tube formation GO:0014020 15 14 0,000 0,05361151 0,08317005 ! peptide cross-linking GO:0018149 14 14 0,000 0,05361151 0,0831001 ! regulation of behavior GO:0050795 14 14 0,000 0,05361151 0,08303027 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,05361151 0,08296055 ! base-excision repair GO:0006284 14 14 0,000 0,05361151 0,08289095 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,05361151 0,08282147 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,05361151 0,08275211 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,05361151 0,08268286 ! formation of primary germ layer GO:0001704 14 14 0,000 0,05361151 0,08261373 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,05361151 0,08254471 ! collagen fibril organization GO:0030199 14 14 0,000 0,05361151 0,08247581 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,05361151 0,08240702 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,05361151 0,08233835 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,05361151 0,08226979 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,05361151 0,08220135 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,05361151 0,08213302 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,05361151 0,0820648 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,05361151 0,0819967 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,05361151 0,0819287 ! vasculature development GO:0001944 97 96 1,000 0,0539613 0,08239493 ! regulation of system process GO:0044057 98 98 1,000 0,05597828 0,08540395 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,05733311 0,08739861 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,05733311 0,08732638 ! positive regulation of ossification GO:0045778 15 15 0,000 0,05733311 0,08725427 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,05733311 0,08718228 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,05733311 0,08711041 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,05733311 0,08703865 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,05733311 0,08696701 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,05733311 0,0868955 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,05733311 0,08682409 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,05733311 0,08675281 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,05733311 0,08668164 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,05733311 0,08661059 ! ovarian follicle development GO:0001541 15 15 0,000 0,05733311 0,08653966 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,05733311 0,08646884 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,05733311 0,08639814 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,05733311 0,08632755 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,05733311 0,08625708 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,05733311 0,08618672 ! heme metabolic process GO:0042168 15 15 0,000 0,05733311 0,08611648 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,05733311 0,08604635 ! chromosome condensation GO:0030261 15 15 0,000 0,05733311 0,08597634 ! response to ionizing radiation GO:0010212 16 15 0,000 0,05733311 0,08590644 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,05733311 0,08583665 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,05733311 0,08576698 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,05733311 0,08569742 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,05733311 0,08562798 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,05733311 0,08555864 ! phospholipid transport GO:0015914 15 15 0,000 0,05733311 0,08548942 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,05733311 0,08542031 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,05733311 0,08535131 ! glutathione metabolic process GO:0006749 16 15 0,000 0,05733311 0,08528242 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,05733311 0,08521365 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,05733311 0,08514498 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,05733311 0,08507643 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,05733311 0,08500798 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,05733311 0,08493965 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,05733311 0,08487142 ! protein homooligomerization GO:0051260 15 15 0,000 0,05733311 0,08480331 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,05733311 0,0847353 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,05802191 0,0856846 ! response to other organism GO:0051707 101 100 1,000 0,05802191 0,08561599 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,06104061 0,08999828 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,06104061 0,08992634 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,06104061 0,08985451 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,06104061 0,0897828 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,06104061 0,0897112 ! learning GO:0007612 16 16 0,000 0,06104061 0,08963972 ! circadian rhythm GO:0007623 16 16 0,000 0,06104061 0,08956835 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,06104061 0,0894971 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,06104061 0,08942595 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,06104061 0,08935492 ! vacuole organization GO:0007033 16 16 0,000 0,06104061 0,08928401 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,06104061 0,0892132 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,06104061 0,08914251 ! segmentation GO:0035282 17 16 0,000 0,06104061 0,08907193 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,06104061 0,08900146 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,06104061 0,08893111 ! iron ion homeostasis GO:0055072 16 16 0,000 0,06104061 0,08886086 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,06104061 0,08879073 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,06104061 0,0887207 ! cell fate specification GO:0001708 16 16 0,000 0,06104061 0,08865079 ! pentose metabolic process GO:0019321 16 16 0,000 0,06104061 0,08858098 ! fatty acid transport GO:0015908 16 16 0,000 0,06104061 0,08851129 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,06104061 0,08844171 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,06104061 0,08837223 ! cofactor catabolic process GO:0051187 16 16 0,000 0,06104061 0,08830286 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,06104061 0,08823361 ! polyol metabolic process GO:0019751 16 16 0,000 0,06104061 0,08816446 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,06104061 0,08809542 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,06104061 0,08802649 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,06104061 0,08795766 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,06104061 0,08788894 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,06104061 0,08782034 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,06104061 0,08775183 ! regulation of coagulation GO:0050818 17 16 0,000 0,06104061 0,08768344 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,06473407 0,09291658 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,06473407 0,09284428 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,06473407 0,09277208 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,06473407 0,0927 ! myelination GO:0042552 17 17 0,000 0,06473407 0,09262802 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,06473407 0,09255616 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,06473407 0,09248441 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,06473407 0,09241278 ! leukocyte adhesion GO:0007159 17 17 0,000 0,06473407 0,09234125 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,06473407 0,09226983 ! sensory perception of smell GO:0007608 17 17 0,000 0,06473407 0,09219853 ! glucose transport GO:0015758 17 17 0,000 0,06473407 0,09212733 ! cell junction assembly GO:0034329 18 17 0,000 0,06473407 0,09205625 ! tissue remodeling GO:0048771 17 17 0,000 0,06473407 0,09198527 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,06473407 0,0919144 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,06473407 0,09184364 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,06473407 0,091773 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,06473407 0,09170246 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,06473407 0,09163202 ! neural crest cell development GO:0014032 19 17 0,000 0,06473407 0,0915617 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,06473407 0,09149148 ! negative regulation of cell development GO:0010721 18 17 0,000 0,06473407 0,09142138 GO:0050768|negative regulation of neurogenesis, ! cell recognition GO:0008037 18 17 0,000 0,06473407 0,09135137 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,06473407 0,09128148 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,06473407 0,09121169 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,06473407 0,09114201 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,06473407 0,09107244 ! pigmentation GO:0043473 17 17 0,000 0,06473407 0,09100297 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,06473407 0,09093361 ! adult locomotory behavior GO:0008344 17 17 0,000 0,06473407 0,09086435 ! embryonic organ development GO:0048568 17 17 0,000 0,06473407 0,0907952 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,06473407 0,09072616 ! liver development GO:0001889 17 17 0,000 0,06473407 0,09065721 ! gene silencing GO:0016458 17 17 0,000 0,06473407 0,09058838 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,06841354 0,09566476 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,06841354 0,09559223 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,06841354 0,09551981 ! meiosis I GO:0007127 18 18 0,000 0,06841354 0,0954475 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,06841354 0,0953753 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,06841354 0,09530321 ! membrane docking GO:0022406 18 18 0,000 0,06841354 0,09523123 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,06841354 0,09515936 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,06841354 0,0950876 ! hexose transport GO:0008645 18 18 0,000 0,06841354 0,09501594 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,06841354 0,09494439 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,06841354 0,09487295 ! striated muscle contraction GO:0006941 18 18 0,000 0,06841354 0,09480162 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,06841354 0,09473039 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,06841354 0,09465927 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,06841354 0,09458826 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,06841354 0,09451736 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,06841354 0,09444656 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,06841354 0,09437586 ! B cell differentiation GO:0030183 18 18 0,000 0,06841354 0,09430527 ! ensheathment of neurons GO:0007272 18 18 0,000 0,06841354 0,09423479 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,06841354 0,09416442 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,06841354 0,09409414 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,06841354 0,09402398 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,07207906 0,09898787 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,07207906 0,09891416 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,07207906 0,09884056 ! regulation of pH GO:0006885 19 19 0,000 0,07207906 0,09876707 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,07207906 0,0986937 ! feeding behavior GO:0007631 19 19 0,000 0,07207906 0,09862043 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,07207906 0,09854727 ! peroxisome organization GO:0007031 19 19 0,000 0,07207906 0,09847421 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,07207906 0,09840127 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,07207906 0,09832843 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,07207906 0,09825571 ! metanephros development GO:0001656 19 19 0,000 0,07207906 0,09818309 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,07207906 0,09811057 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,07207906 0,09803817 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,07207906 0,09796587 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,07207906 0,09789367 ! peripheral nervous system development GO:0007422 19 19 0,000 0,07207906 0,09782159 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,07207906 0,09774961 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,07207906 0,09767773 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,07207906 0,09760596 ! eye morphogenesis GO:0048592 19 19 0,000 0,07207906 0,0975343 ! regulation of cell shape GO:0008360 21 19 0,000 0,07207906 0,09746274 ! placenta development GO:0001890 19 19 0,000 0,07207906 0,09739129 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,0757307 0,10225031 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,0757307 0,10217546 ! organic ether metabolic process GO:0018904 20 20 0,000 0,0757307 0,10210072 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,0757307 0,10202608 ! neural tube development GO:0021915 21 20 0,000 0,0757307 0,10195155 ! nucleus organization GO:0006997 20 20 0,000 0,0757307 0,10187714 ! phagocytosis GO:0006909 21 20 0,000 0,0757307 0,10180283 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,0757307 0,10172863 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,0757307 0,10165454 ! protein targeting to membrane GO:0006612 22 20 0,000 0,0757307 0,10158055 ! chromatin remodeling GO:0006338 20 20 0,000 0,0757307 0,10150667 ! lipid oxidation GO:0034440 20 20 0,000 0,0757307 0,10143291 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,0757307 0,10135924 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,0757307 0,10128569 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,0757307 0,10121224 ! RNA modification GO:0009451 20 20 0,000 0,0757307 0,1011389 ! single fertilization GO:0007338 21 20 0,000 0,0757307 0,10106566 ! regulation of B cell activation GO:0050864 20 20 0,000 0,0757307 0,10099253 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,07936849 0,10576727 ! mRNA catabolic process GO:0006402 21 21 0,000 0,07936849 0,10569085 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,07936849 0,10561454 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,07936849 0,10553834 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,07936849 0,10546224 ! Notch signaling pathway GO:0007219 22 21 0,000 0,07936849 0,10538626 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,07936849 0,10531039 ! ear morphogenesis GO:0042471 21 21 0,000 0,07936849 0,10523463 ! cholesterol transport GO:0030301 21 21 0,000 0,07936849 0,10515897 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,07936849 0,10508343 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,07936849 0,10500799 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,07936849 0,10493266 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,07936849 0,10485744 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,07936849 0,10478233 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,07936849 0,10470733 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,07936849 0,10463243 ! regulation of proteolysis GO:0030162 21 21 0,000 0,07936849 0,10455764 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,07936849 0,10448295 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,07936849 0,10440837 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,07936849 0,1043339 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,0829925 0,10902008 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,0829925 0,10894243 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,0829925 0,10886489 ! sister chromatid segregation GO:0000819 22 22 0,000 0,0829925 0,10878746 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,0829925 0,10871015 ! regulation of ion transport GO:0043269 22 22 0,000 0,0829925 0,10863294 ! odontogenesis GO:0042476 22 22 0,000 0,0829925 0,10855584 ! cell junction organization GO:0034330 23 22 0,000 0,0829925 0,10847885 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,0829925 0,10840197 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,0829925 0,10832519 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,0829925 0,10824853 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,0829925 0,10817198 ! ovulation cycle process GO:0022602 22 22 0,000 0,0829925 0,10809553 ! spindle organization GO:0007051 22 22 0,000 0,0829925 0,10801919 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,0829925 0,10794296 ! cell chemotaxis GO:0060326 23 22 0,000 0,0829925 0,10786684 GO:0030595|leukocyte chemotaxis, ! erythrocyte differentiation GO:0030218 23 22 0,000 0,0829925 0,10779082 ! male sex differentiation GO:0046661 22 22 0,000 0,0829925 0,10771491 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,0829925 0,10763911 ! biopolymer methylation GO:0043414 22 22 0,000 0,0829925 0,10756341 GO:0032259|methylation, ! neuron migration GO:0001764 22 22 0,000 0,0829925 0,10748782 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,0829925 0,10741234 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,0829925 0,10733696 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,0829925 0,10726169 ! aerobic respiration GO:0009060 22 22 0,000 0,0829925 0,10718653 ! cytokinesis GO:0000910 23 22 0,000 0,0829925 0,10711147 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,0829925 0,10703651 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,08660276 0,11161461 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,08660276 0,11153661 ! viral infectious cycle GO:0019058 23 23 0,000 0,08660276 0,11145872 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,08660276 0,11138094 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,08660276 0,11130327 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,08660276 0,11122571 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,08660276 0,11114825 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,08660276 0,11107091 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,08660276 0,11099367 ! endocrine system development GO:0035270 23 23 0,000 0,08660276 0,11091654 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,08660276 0,11083951 ! positive regulation of growth GO:0045927 23 23 0,000 0,08660276 0,11076259 ! female gonad development GO:0008585 23 23 0,000 0,08660276 0,11068578 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,08660276 0,11060907 ! lipid homeostasis GO:0055088 23 23 0,000 0,08660276 0,11053248 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,08660276 0,11045598 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,08660276 0,11037959 ! regulation of action potential GO:0001508 24 24 0,000 0,09019934 0,11488416 ! gliogenesis GO:0042063 24 24 0,000 0,09019934 0,11480482 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,09019934 0,11472559 ! glucose homeostasis GO:0042593 24 24 0,000 0,09019934 0,11464647 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,09019934 0,11456746 ! T cell differentiation GO:0030217 24 24 0,000 0,09019934 0,11448856 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,09019934 0,11440976 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,09019934 0,11433108 ! ovulation cycle GO:0042698 24 24 0,000 0,09019934 0,1142525 ! fertilization GO:0009566 25 24 0,000 0,09019934 0,11417403 ! maintenance of protein location GO:0045185 25 24 0,000 0,09019934 0,11409567 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,09019934 0,11401741 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,09019934 0,11393926 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,09019934 0,11386122 ! glucan metabolic process GO:0044042 25 24 0,000 0,09019934 0,11378329 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,09378228 0,11822212 ! negative regulation of secretion GO:0051048 26 25 0,000 0,09378228 0,11814131 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,09378228 0,11806061 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,09378228 0,11798003 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,09378228 0,11789955 ! cellular component disassembly GO:0022411 26 25 0,000 0,09378228 0,11781918 ! endosome transport GO:0016197 25 25 0,000 0,09378228 0,11773892 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,09378228 0,11765877 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,09378228 0,11757873 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,09378228 0,1174988 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,09378228 0,11741898 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,09378228 0,11733927 ! excretion GO:0007588 25 25 0,000 0,09378228 0,11725966 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,09378228 0,11718016 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,09378228 0,11710077 ! gastrulation GO:0007369 25 25 0,000 0,09378228 0,11702149 ! heart morphogenesis GO:0003007 25 25 0,000 0,09378228 0,11694231 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,09378228 0,11686324 ! regulation of endocytosis GO:0030100 25 25 0,000 0,09378228 0,11678428 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,09378228 0,11670543 ! positive regulation of binding GO:0051099 27 26 0,000 0,09735163 0,12106548 ! positive regulation of defense response GO:0031349 26 26 0,000 0,09735163 0,12098385 ! glycolysis GO:0006096 26 26 0,000 0,09735163 0,12090232 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,09735163 0,12082091 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,09735163 0,1207396 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,09735163 0,1206584 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,09735163 0,12057732 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,09735163 0,12049634 ! cellular defense response GO:0006968 26 26 0,000 0,09735163 0,12041547 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,09735163 0,12033471 ! double-strand break repair GO:0006302 27 26 0,000 0,09735163 0,12025405 ! regulation of protein secretion GO:0050708 26 26 0,000 0,09735163 0,12017351 ! germ cell development GO:0007281 27 26 0,000 0,09735163 0,12009307 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,09735163 0,12001274 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,09735163 0,11993252 ! response to insulin stimulus GO:0032868 28 26 0,000 0,09735163 0,1198524 ! synapse organization GO:0050808 26 26 0,000 0,09735163 0,11977239 ! chloride transport GO:0006821 27 27 0,000 0,10090743 0,12406431 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,10090743 0,1239816 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,10090743 0,123899 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,10090743 0,12381651 ! learning or memory GO:0007611 28 27 0,000 0,10090743 0,12373413 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,10090743 0,12365186 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,10090743 0,1235697 ! peptide metabolic process GO:0006518 29 27 0,000 0,10090743 0,12348765 ! activation of caspase activity GO:0006919 27 27 0,000 0,10090743 0,12340571 ! mesenchymal cell development GO:0014031 29 27 0,000 0,10090743 0,12332387 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,10090743 0,12324215 ! defense response to bacterium GO:0042742 27 27 0,000 0,10090743 0,12316053 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,10090743 0,12307902 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,10090743 0,12299762 ! cell growth GO:0016049 27 27 0,000 0,10090743 0,12291632 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,10444975 0,12714722 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,10444975 0,12706329 ! carbohydrate transport GO:0008643 28 28 0,000 0,10444975 0,12697948 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,10444975 0,12689577 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,10444975 0,12681218 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,10444975 0,1267287 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,10444975 0,12664532 ! histone modification GO:0016570 28 28 0,000 0,10444975 0,12656206 ! developmental growth GO:0048589 28 28 0,000 0,10444975 0,1264789 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,10444975 0,12639586 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,10797863 0,13058045 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,10797863 0,13049482 ! viral reproductive process GO:0022415 29 29 0,000 0,10797863 0,13040931 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,10797863 0,13032391 ! leukocyte migration GO:0050900 30 29 0,000 0,10797863 0,13023862 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,10797863 0,13015344 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,10797863 0,13006837 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,10797863 0,12998341 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,10797863 0,12989857 ! tRNA processing GO:0008033 29 29 0,000 0,10797863 0,12981383 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,10797863 0,12972921 ! covalent chromatin modification GO:0016569 29 29 0,000 0,10797863 0,1296447 ! adult behavior GO:0030534 30 29 0,000 0,10797863 0,12956029 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,10797863 0,129476 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,10797863 0,12939181 ! response to UV GO:0009411 29 29 0,000 0,10797863 0,12930774 ! transition metal ion transport GO:0000041 31 30 0,000 0,11149411 0,13343094 ! RNA catabolic process GO:0006401 30 30 0,000 0,11149411 0,13334435 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,11149411 0,13325788 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,11149411 0,13317151 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,11149411 0,13308526 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,11149411 0,13299912 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,11149411 0,13291309 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,11149411 0,13282718 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,11149411 0,13274137 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,11149411 0,13265568 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,11149411 0,13257009 ! regulation of ossification GO:0030278 30 30 0,000 0,11149411 0,13248462 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,11149411 0,13239926 ! regulation of inflammatory response GO:0050727 30 30 0,000 0,11149411 0,132314 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,11149411 0,13222886 ! vesicle organization GO:0016050 30 30 0,000 0,11149411 0,13214382 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,11149411 0,1320589 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,11499625 0,13611952 ! membrane fusion GO:0006944 31 31 0,000 0,11499625 0,13603215 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,11499625 0,13594489 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,11499625 0,13585775 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,11499625 0,13577072 ! ion transmembrane transport GO:0034220 31 31 0,000 0,11499625 0,1356838 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,11499625 0,13559699 ! digestion GO:0007586 31 31 0,000 0,11499625 0,13551029 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,11499625 0,1354237 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,11499625 0,13533722 ! camera-type eye development GO:0043010 31 31 0,000 0,11499625 0,13525085 ! extracellular matrix organization GO:0030198 31 31 0,000 0,11499625 0,1351646 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,11499625 0,13507845 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,11499625 0,13499241 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,11499625 0,13490649 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,11499625 0,13482067 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,11499625 0,13473496 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,11848509 0,13873445 ! cell redox homeostasis GO:0045454 32 32 0,000 0,11848509 0,13864637 ! muscle fiber development GO:0048747 32 32 0,000 0,11848509 0,13855839 ! glucose catabolic process GO:0006007 32 32 0,000 0,11848509 0,13847053 ! lipid modification GO:0030258 32 32 0,000 0,11848509 0,13838278 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,11848509 0,13829514 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,11848509 0,13820761 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,11848509 0,1381202 ! cell maturation GO:0048469 32 32 0,000 0,11848509 0,13803289 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,11848509 0,13794569 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,11848509 0,1378586 ! nuclear export GO:0051168 32 32 0,000 0,11848509 0,13777163 ! kidney development GO:0001822 32 32 0,000 0,11848509 0,13768476 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,11848509 0,137598 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,11848509 0,13751135 ! negative regulation of cell size GO:0045792 33 33 0,000 0,12196069 0,14145598 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,12196069 0,14136702 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,12196069 0,14127816 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,12196069 0,14118942 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,12196069 0,14110079 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,12196069 0,14101227 ! regulation of actin filament length GO:0030832 34 34 0,000 0,1254231 0,14492462 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,1254231 0,14483381 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,1254231 0,14474312 ! ear development GO:0043583 34 34 0,000 0,1254231 0,14465254 ! muscle cell differentiation GO:0042692 35 34 0,000 0,1254231 0,14456208 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,1254231 0,14447173 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,1254231 0,14438149 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,1254231 0,14429136 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,1254231 0,14420135 ! secondary metabolic process GO:0019748 34 34 0,000 0,1254231 0,14411145 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,1254231 0,14402166 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,1254231 0,14393198 ! viral reproduction GO:0016032 34 34 0,000 0,1254231 0,14384242 ! acute inflammatory response GO:0002526 35 35 0,000 0,12887235 0,1477063 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,12887235 0,1476145 ! regulation of cellular component size GO:0032535 35 35 0,000 0,12887235 0,14752282 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,12887235 0,14743124 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,12887235 0,14733979 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,12887235 0,14724844 ! inorganic anion transport GO:0015698 35 35 0,000 0,12887235 0,14715721 ! regulation of immune effector process GO:0002697 35 35 0,000 0,12887235 0,14706609 ! hydrogen transport GO:0006818 36 36 0,000 0,1323085 0,15089391 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,1323085 0,15080059 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,1323085 0,15070739 ! regulation of mitosis GO:0007088 37 36 0,000 0,1323085 0,1506143 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,1323085 0,15052133 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,1323085 0,15042848 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,1323085 0,15033573 GO:0045937|positive regulation of phosphate metabolic process, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,1323085 0,15024311 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,1323085 0,15015059 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,1323085 0,15005819 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,1323085 0,1499659 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,1323085 0,14987373 ! gonad development GO:0008406 36 36 0,000 0,1323085 0,14978167 ! regulation of lipase activity GO:0060191 36 36 0,000 0,1323085 0,14968972 ! meiosis GO:0007126 37 37 0,000 0,13573159 0,1534683 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,13573159 0,1533742 ! response to drug GO:0042493 37 37 0,000 0,13573159 0,15328022 ! lung development GO:0030324 38 37 0,000 0,13573159 0,15318636 ! eye development GO:0001654 37 37 0,000 0,13573159 0,15309261 ! negative regulation of growth GO:0045926 37 37 0,000 0,13573159 0,15299898 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,13573159 0,15290546 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,13573159 0,15281205 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,13573159 0,15271876 ! positive regulation of secretion GO:0051047 39 38 0,000 0,13914168 0,15646011 ! neurotransmitter transport GO:0006836 40 38 0,000 0,13914168 0,15636471 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,13914168 0,15626942 ! exocytosis GO:0006887 40 38 0,000 0,13914168 0,15617425 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,13914168 0,1560792 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,13914168 0,15598426 ! chromosome segregation GO:0007059 38 38 0,000 0,13914168 0,15588944 ! urogenital system development GO:0001655 38 38 0,000 0,13914168 0,15579473 ! hexose catabolic process GO:0019320 38 38 0,000 0,13914168 0,15570013 ! RNA elongation GO:0006354 38 38 0,000 0,13914168 0,15560566 ! meiotic cell cycle GO:0051321 38 38 0,000 0,13914168 0,15551129 ! regulation of neurological system process GO:0031644 38 38 0,000 0,13914168 0,15541704 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,13914168 0,15532291 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,14253881 0,15901879 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,14253881 0,15892259 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,14253881 0,1588265 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,14253881 0,15873054 ! respiratory system development GO:0060541 40 39 0,000 0,14253881 0,15863468 ! developmental maturation GO:0021700 39 39 0,000 0,14253881 0,15853895 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,14253881 0,15844333 ! limb development GO:0060173 39 39 0,000 0,14253881 0,15834782 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! positive regulation of cell motion GO:0051272 39 39 0,000 0,14253881 0,15825243 ! DNA catabolic process GO:0006308 41 40 0,000 0,14592304 0,16191219 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,14592304 0,16181477 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,14592304 0,16171747 ! amine catabolic process GO:0009310 42 41 0,000 0,14929439 0,16535431 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,14929439 0,16525499 ! regulation of caspase activity GO:0043281 41 41 0,000 0,14929439 0,1651558 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,14929439 0,16505673 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,14929439 0,16495777 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,14929439 0,16485894 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,15265293 0,16846668 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,15265293 0,16836586 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,15265293 0,16826516 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,15265293 0,16816459 ! protein ubiquitination GO:0016567 43 42 0,000 0,15265293 0,16806413 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,15265293 0,16796379 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 0,000 0,15265293 0,16786358 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,15265293 0,16776348 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,15265293 0,1676635 ! reproductive structure development GO:0048608 43 43 0,000 0,1559987 0,17123622 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,1559987 0,17113429 ! mitochondrion organization GO:0007005 44 43 0,000 0,1559987 0,17103248 ! alcohol catabolic process GO:0046164 43 43 0,000 0,1559987 0,1709308 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,1559987 0,17082924 ! humoral immune response GO:0006959 44 44 0,000 0,15933175 0,17437554 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,15933175 0,17427205 ! mRNA transport GO:0051028 44 44 0,000 0,15933175 0,17416869 ! protein import into nucleus GO:0006606 44 44 0,000 0,15933175 0,17406545 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,15933175 0,17396233 ! vitamin metabolic process GO:0006766 44 44 0,000 0,15933175 0,17385933 ! amine biosynthetic process GO:0009309 46 45 0,000 0,16265212 0,17737743 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,16265212 0,17727253 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,16265212 0,17716776 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,16265212 0,17706311 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,16265212 0,17695859 ! nuclear import GO:0051170 45 45 0,000 0,16265212 0,17685419 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,16265212 0,17674991 ! protein processing GO:0016485 45 45 0,000 0,16265212 0,17664576 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,16595985 0,18013193 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,16595985 0,1800259 ! tube morphogenesis GO:0035239 47 46 0,000 0,16595985 0,17992001 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,16595985 0,17981423 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,16595985 0,17970858 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,16595985 0,17960306 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,16595985 0,17949766 ! regulation of membrane potential GO:0042391 46 46 0,000 0,16595985 0,17939238 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,16925501 0,182847 ! regulation of blood pressure GO:0008217 48 47 0,000 0,16925501 0,18273988 ! sex differentiation GO:0007548 47 47 0,000 0,16925501 0,18263289 ! rhythmic process GO:0048511 47 47 0,000 0,16925501 0,18252603 ! regulation of catabolic process GO:0009894 48 47 0,000 0,16925501 0,18241929 ! calcium ion transport GO:0006816 48 48 0,000 0,17253762 0,18584853 ! actin filament organization GO:0007015 50 48 0,000 0,17253762 0,18573998 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,17253762 0,18563155 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,17253762 0,18552324 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,17253762 0,18541507 ! protein localization in nucleus GO:0034504 48 48 0,000 0,17253762 0,18530702 ! DNA recombination GO:0006310 48 48 0,000 0,17253762 0,18519909 ! leukocyte differentiation GO:0002521 50 49 0,000 0,17580775 0,18859935 ! cell cycle arrest GO:0007050 49 49 0,000 0,17580775 0,18848963 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,17580775 0,18838005 ! divalent metal ion transport GO:0070838 49 49 0,000 0,17580775 0,18827059 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,17580775 0,18816125 GO:0060538|skeletal muscle organ development, ! regulation of ligase activity GO:0051340 50 49 0,000 0,17580775 0,18805205 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,17580775 0,18794297 ! regulation of defense response GO:0031347 50 50 0,000 0,17906542 0,19131454 ! negative regulation of transport GO:0051051 51 50 0,000 0,17906542 0,1912037 ! chromatin assembly GO:0031497 50 50 0,000 0,17906542 0,19109298 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,17906542 0,19098239 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,17906542 0,19087194 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,17906542 0,19076161 ! transcription initiation GO:0006352 50 50 0,000 0,17906542 0,1906514 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,17906542 0,19054133 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,1823107 0,19388264 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,1823107 0,19377083 ! rRNA metabolic process GO:0016072 51 51 0,000 0,1823107 0,19365915 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,1823107 0,19354759 ! protein maturation GO:0051604 51 51 0,000 0,1823107 0,19343617 ! RNA localization GO:0006403 52 52 0,000 0,18554362 0,1967531 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,18554362 0,19663996 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,18554362 0,19652695 ! cell fate commitment GO:0045165 52 52 0,000 0,18554362 0,19641407 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,18554362 0,19630132 ! response to light stimulus GO:0009416 53 52 0,000 0,18554362 0,19618869 ! sodium ion transport GO:0006814 53 53 0,000 0,18876423 0,19947963 ! tRNA metabolic process GO:0006399 53 53 0,000 0,18876423 0,19936532 ! response to hypoxia GO:0001666 53 53 0,000 0,18876423 0,19925113 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,18876423 0,19913708 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,18876423 0,19902316 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,18876423 0,19890936 ! regulation of protein transport GO:0051223 53 53 0,000 0,18876423 0,1987957 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,19197257 0,20205908 ! response to oxygen levels GO:0070482 55 54 0,000 0,19197257 0,20194375 ! response to virus GO:0009615 54 54 0,000 0,19197257 0,20182855 ! hormone metabolic process GO:0042445 55 54 0,000 0,19197257 0,20171349 ! sulfur metabolic process GO:0006790 55 54 0,000 0,19197257 0,20159855 ! nucleosome organization GO:0034728 55 55 0,000 0,1951687 0,20483822 ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,1951687 0,20472163 ! in utero embryonic development GO:0001701 55 55 0,000 0,1951687 0,20460518 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,1951687 0,20448886 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,1951687 0,20437268 ! reproductive developmental process GO:0003006 56 56 0,000 0,19835265 0,20758883 ! extracellular structure organization GO:0043062 56 56 0,000 0,19835265 0,20747101 ! regulation of protein localization GO:0032880 58 57 0,000 0,20152446 0,21066908 ! innate immune response GO:0045087 58 58 0,000 0,20468419 0,21385089 ! dephosphorylation GO:0016311 60 59 0,000 0,20783188 0,21701652 ! sterol metabolic process GO:0016125 59 59 0,000 0,20783188 0,21689363 ! protein localization in organelle GO:0033365 59 59 0,000 0,20783188 0,21677089 ! potassium ion transport GO:0006813 60 60 0,000 0,21096757 0,21991699 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,21096757 0,21979267 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,21409131 0,22292106 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,21409131 0,22279519 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,21409131 0,22266946 ! lipid transport GO:0006869 62 62 0,000 0,21720313 0,22577855 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,21720313 0,22565128 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,21720313 0,22552415 ! protein import GO:0017038 62 62 0,000 0,21720313 0,22539717 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,21720313 0,22527033 ! regulation of secretion GO:0051046 65 63 0,000 0,22030309 0,22835691 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,22030309 0,22822855 ! glucose metabolic process GO:0006006 63 63 0,000 0,22030309 0,22810033 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,22339122 0,2311679 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,22339122 0,23103817 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,22339122 0,2309086 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,22339122 0,23077916 ! regulation of hormone levels GO:0010817 66 65 0,000 0,22646758 0,23382619 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,2295322 0,23685769 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! DNA packaging GO:0006323 66 66 0,000 0,2295322 0,23672515 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,2295322 0,23659275 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,2295322 0,2364605 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,23258512 0,23947172 ! muscle contraction GO:0006936 67 67 0,000 0,23258512 0,23933801 ! striated muscle tissue development GO:0014706 69 67 0,000 0,23258512 0,23920445 ! response to radiation GO:0009314 70 68 0,000 0,2356264 0,24219713 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,2356264 0,24206212 ! regulation of cell size GO:0008361 68 68 0,000 0,2356264 0,24192727 ! sensory perception of sound GO:0007605 71 69 0,000 0,23865606 0,24490152 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,23865606 0,24476523 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,23865606 0,2446291 ! positive regulation of transport GO:0051050 71 70 0,000 0,24167416 0,24758504 ! growth GO:0040007 70 70 0,000 0,24167416 0,24744749 ! muscle tissue development GO:0060537 72 70 0,000 0,24167416 0,2473101 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,24167416 0,24717286 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,24468074 0,25010905 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,24468074 0,2499704 ! regulation of cell migration GO:0030334 71 71 0,000 0,24468074 0,24983192 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,24468074 0,24969358 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,24468074 0,2495554 ! secretion by cell GO:0032940 75 72 0,000 0,24767584 0,25247045 ! muscle system process GO:0003012 72 72 0,000 0,24767584 0,25233089 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,24767584 0,25219148 ! sensory organ development GO:0007423 72 72 0,000 0,24767584 0,25205222 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,25363176 0,25797094 ! response to oxidative stress GO:0006979 76 75 0,000 0,25659267 0,26083855 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,26248059 0,26667681 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,26540769 0,26950213 ! metal ion homeostasis GO:0055065 78 78 0,000 0,26540769 0,26935373 ! regulation of locomotion GO:0040012 79 79 0,000 0,26832359 0,27216311 ! nuclear transport GO:0051169 79 79 0,000 0,26832359 0,27201341 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 0,000 0,26832359 0,27186387 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,27122835 0,27465596 ! lipid catabolic process GO:0016042 82 81 0,000 0,274122 0,27743375 ! ncRNA processing GO:0034470 83 83 0,000 0,27987615 0,28310195 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,28273673 0,28583861 ! regulation of cellular localization GO:0060341 86 85 0,000 0,28558636 0,28856122 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,28558636 0,2884031 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,28842509 0,29111032 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,28842509 0,29095098 ! heart development GO:0007507 90 87 0,000 0,29125296 0,29364289 ! male gamete generation GO:0048232 90 88 0,000 0,29407 0,29632095 GO:0007283|spermatogenesis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,29687626 0,29898522 ! brain development GO:0007420 91 90 0,000 0,29967177 0,30163576 ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,30245658 0,30427264 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,30245658 0,30410665 ! visual perception GO:0007601 93 92 0,000 0,30523073 0,30672859 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,30523073 0,30656144 ! pattern specification process GO:0007389 96 94 0,000 0,31074718 0,31193195 ! cofactor metabolic process GO:0051186 95 94 0,000 0,31074718 0,31176214 ! regulation of cell growth GO:0001558 97 96 0,000 0,31622144 0,31708168 ! endocytosis GO:0006897 99 98 0,000 0,32165382 0,32235345 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,32165382 0,32217826 ! blood circulation GO:0008015 99 98 0,000 0,32165382 0,32200326 GO:0003013|circulatory system process, ! muscle organ development GO:0007517 102 100 0,000 0,32704463 0,32722218 ! hemopoiesis GO:0030097 104 100 0,000 0,32704463 0,32704463