pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/75-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! B cell proliferation GO:0042100 18 10 3,000 1,007E-08 2,423E-05 ! polyol catabolic process GO:0046174 7 5 2,000 1,867E-07 2,246E-04 GO:0019405|alditol catabolic process, ! regulation of interleukin-5 production GO:0032674 9 6 2,000 3,727E-07 2,989E-04 ! lymphocyte proliferation GO:0046651 48 24 3,000 4,951E-07 2,978E-04 ! leukocyte proliferation GO:0070661 52 26 3,000 6,938E-07 3,338E-04 GO:0032943|mononuclear cell proliferation, ! L-glutamate transport GO:0015813 22 12 2,000 4,052E-06 1,625E-03 GO:0015800|acidic amino acid transport, ! cellular carbohydrate catabolic process GO:0044275 15 13 2,000 5,257E-06 1,807E-03 ! hair follicle morphogenesis GO:0031069 26 14 2,000 6,678E-06 2,008E-03 ! fructose metabolic process GO:0006000 25 16 2,000 1,023E-05 2,736E-03 ! epidermis morphogenesis GO:0048730 40 18 2,000 1,485E-05 3,574E-03 ! negative regulation of cytokine production GO:0001818 40 23 2,000 3,193E-05 6,983E-03 ! response to molecule of bacterial origin GO:0002237 34 23 2,000 3,193E-05 6,401E-03 ! alditol metabolic process GO:0019400 38 24 2,000 3,642E-05 6,74E-03 ! B cell activation GO:0042113 160 71 3,000 4,113E-05 7,069E-03 ! sperm motility GO:0030317 31 25 2,000 4,13E-05 6,625E-03 ! telomere organization GO:0032200 43 25 2,000 4,13E-05 6,211E-03 GO:0000723|telomere maintenance, ! molting cycle process GO:0022404 50 26 2,000 4,66E-05 6,595E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! response to estradiol stimulus GO:0032355 40 26 2,000 4,66E-05 6,229E-03 ! response to steroid hormone stimulus GO:0048545 137 78 3,000 5,953E-05 7,538E-03 ! blood coagulation, extrinsic pathway GO:0007598 9 5 1,000 7,107E-05 8,55E-03 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 1,000 7,107E-05 8,143E-03 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 1,000 7,107E-05 7,772E-03 ! microvillus organization GO:0032528 7 5 1,000 7,107E-05 7,435E-03 GO:0030033|microvillus assembly, ! nucleoside monophosphate catabolic process GO:0009125 11 5 1,000 7,107E-05 7,125E-03 ! positive regulation of interleukin-4 production GO:0032753 8 5 1,000 7,107E-05 6,84E-03 GO:0032754|positive regulation of interleukin-5 production, ! negative regulation of interleukin-6 production GO:0032715 5 5 1,000 7,107E-05 6,577E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 7,107E-05 6,333E-03 GO:0042634|regulation of hair cycle, ! receptor biosynthetic process GO:0032800 7 5 1,000 7,107E-05 6,107E-03 ! hexose biosynthetic process GO:0019319 48 32 2,000 8,787E-05 7,29E-03 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 1,000 1,064E-04 8,535E-03 ! interaction with symbiont GO:0051702 13 6 1,000 1,064E-04 8,259E-03 ! response to exogenous dsRNA GO:0043330 10 6 1,000 1,064E-04 8,001E-03 ! regulation of interleukin-13 production GO:0032656 11 6 1,000 1,064E-04 7,759E-03 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 1,000 1,064E-04 7,531E-03 ! negative regulation of multicellular organismal process GO:0051241 166 93 3,000 1,182E-04 8,124E-03 ! monosaccharide biosynthetic process GO:0046364 52 36 2,000 1,255E-04 8,388E-03 ! organic anion transport GO:0015711 68 37 2,000 1,363E-04 8,865E-03 ! cyclic nucleotide metabolic process GO:0009187 63 37 2,000 1,363E-04 8,631E-03 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 1,000 1,487E-04 9,175E-03 GO:0045346|regulation of MHC class II biosynthetic process, ! regulation of odontogenesis GO:0042481 13 7 1,000 1,487E-04 8,946E-03 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 1,000 1,487E-04 8,728E-03 ! negative regulation of interferon-gamma production GO:0032689 12 7 1,000 1,487E-04 8,52E-03 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 1,000 1,487E-04 8,322E-03 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 1,487E-04 8,133E-03 ! polyol metabolic process GO:0019751 66 41 2,000 1,856E-04 9,923E-03 ! regulation of interferon-alpha production GO:0032647 11 8 1,000 1,98E-04 0,01035388 ! regulation of interleukin-4 production GO:0032673 17 8 1,000 1,98E-04 0,01013358 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 1,98E-04 9,922E-03 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 1,98E-04 9,72E-03 GO:0000076|DNA replication checkpoint, ! alcohol biosynthetic process GO:0046165 59 42 2,000 1,995E-04 9,599E-03 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 2,000 2,292E-04 0,01081441 ! JAK-STAT cascade GO:0007259 71 44 2,000 2,292E-04 0,01060644 ! maintenance of location in cell GO:0051651 97 44 2,000 2,292E-04 0,01040632 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 2,541E-04 0,01132015 ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 2,541E-04 0,01111433 ! regulation of type I interferon production GO:0032479 12 9 1,000 2,541E-04 0,01091586 ! negative regulation of cytokine secretion GO:0050710 14 9 1,000 2,541E-04 0,01072435 ! pyrimidine base metabolic process GO:0006206 17 9 1,000 2,541E-04 0,01053945 ! mitochondrion localization GO:0051646 15 9 1,000 2,541E-04 0,01036082 ! response to calcium ion GO:0051592 81 47 2,000 2,79E-04 0,01118916 ! regulation of adaptive immune response GO:0002819 84 47 2,000 2,79E-04 0,01100573 ! JNK cascade GO:0007254 91 47 2,000 2,79E-04 0,01082822 ! mitochondrial transport GO:0006839 82 48 2,000 2,971E-04 0,01134478 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 2,000 3,158E-04 0,01187284 ! response to temperature stimulus GO:0009266 76 49 2,000 3,158E-04 0,01169018 ! response to dsRNA GO:0043331 20 10 1,000 3,17E-04 0,01155721 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 3,17E-04 0,01138471 ! response to estrogen stimulus GO:0043627 93 51 2,000 3,556E-04 0,01258189 ! negative regulation of muscle development GO:0048635 20 11 1,000 3,868E-04 0,01348773 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 3,868E-04 0,01329505 ! negative regulation of proteolysis GO:0045861 25 11 1,000 3,868E-04 0,0131078 ! negative regulation of tumor necrosis factor production GO:0032720 15 11 1,000 3,868E-04 0,01292574 ! regulation of isotype switching GO:0045191 22 11 1,000 3,868E-04 0,01274868 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 3,868E-04 0,0125764 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 3,868E-04 0,01240871 ! respiratory electron transport chain GO:0022904 76 53 2,000 3,985E-04 0,01261462 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 1,000 4,634E-04 0,01447837 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 4,634E-04 0,01429275 ! cartilage condensation GO:0001502 20 12 1,000 4,634E-04 0,01411183 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 4,634E-04 0,01393543 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 4,634E-04 0,01376339 GO:0042130|negative regulation of T cell proliferation, ! maintenance of location GO:0051235 118 57 2,000 4,939E-04 0,01449073 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 5,466E-04 0,01584617 ! regulation of cytokine production during immune response GO:0002718 23 13 1,000 5,466E-04 0,01565752 ! regulation of epidermis development GO:0045682 19 13 1,000 5,466E-04 0,01547332 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 5,466E-04 0,0152934 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 5,466E-04 0,01511761 ! lactation GO:0007595 26 14 1,000 6,366E-04 0,01740636 ! embryo implantation GO:0007566 30 14 1,000 6,366E-04 0,01721078 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 6,366E-04 0,01701955 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 6,366E-04 0,01683252 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 6,366E-04 0,01664956 ! negative regulation of protein secretion GO:0050709 28 14 1,000 6,366E-04 0,01647053 ! cAMP biosynthetic process GO:0006171 23 14 1,000 6,366E-04 0,01629531 ! nucleoside monophosphate metabolic process GO:0009123 107 63 2,000 6,625E-04 0,01677955 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 7,259E-04 0,01819392 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 7,333E-04 0,01818898 ! positive regulation of axonogenesis GO:0050772 28 15 1,000 7,333E-04 0,01800338 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 7,333E-04 0,01782153 ! cell killing GO:0001906 29 15 1,000 7,333E-04 0,01764331 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 1,000 7,333E-04 0,01746863 ! adaptive immune response GO:0002250 119 67 2,000 7,931E-04 0,01870758 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! amino acid transport GO:0006865 125 68 2,000 8,281E-04 0,0193436 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 8,366E-04 0,01935443 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 8,366E-04 0,01917011 ! DNA replication initiation GO:0006270 27 16 1,000 8,366E-04 0,01898926 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 8,366E-04 0,01881179 ! positive regulation of cytokine secretion GO:0050715 26 16 1,000 8,366E-04 0,0186376 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 8,366E-04 0,01846662 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! gene silencing by RNA GO:0031047 36 17 1,000 9,465E-04 0,0207024 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 9,465E-04 0,02051589 ! nucleobase metabolic process GO:0009112 37 17 1,000 9,465E-04 0,02033271 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 1,000 9,465E-04 0,02015278 GO:0002712|regulation of B cell mediated immunity, ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 9,465E-04 0,019976 ! organelle localization GO:0051640 136 74 2,000 1,059E-03 0,02215162 ! response to retinoic acid GO:0032526 26 18 1,000 1,063E-03 0,02204702 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 1,063E-03 0,02185859 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 1,063E-03 0,02167334 ! nerve development GO:0021675 28 18 1,000 1,063E-03 0,02149121 ! skin development GO:0043588 36 19 1,000 1,186E-03 0,0237779 ! response to vitamin A GO:0033189 27 19 1,000 1,186E-03 0,02358139 ! response to lipopolysaccharide GO:0032496 30 19 1,000 1,186E-03 0,0233881 ! G1 phase GO:0051318 40 19 1,000 1,186E-03 0,02319795 ! estrogen receptor signaling pathway GO:0030520 38 19 1,000 1,186E-03 0,02301087 ! blood coagulation GO:0007596 146 78 2,000 1,233E-03 0,02373302 GO:0050817|coagulation, ! cAMP metabolic process GO:0046058 36 20 1,000 1,315E-03 0,02511794 ! response to vitamin GO:0033273 31 20 1,000 1,315E-03 0,02492016 ! cellular response to starvation GO:0009267 33 20 1,000 1,315E-03 0,02472548 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,315E-03 0,02453381 ! response to metal ion GO:0010038 140 80 2,000 1,326E-03 0,02455031 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 1,451E-03 0,02665579 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 1,451E-03 0,02645385 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 1,451E-03 0,02625495 ! hemostasis GO:0007599 158 84 2,000 1,527E-03 0,02740977 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 1,594E-03 0,02840301 ! regulation of cytokine secretion GO:0050707 37 22 1,000 1,594E-03 0,02819416 ! activation of JUN kinase activity GO:0007257 42 22 1,000 1,594E-03 0,02798837 ! protein stabilization GO:0050821 39 22 1,000 1,594E-03 0,02778555 ! alcohol catabolic process GO:0046164 130 86 2,000 1,633E-03 0,02827134 ! response to inorganic substance GO:0010035 153 86 2,000 1,633E-03 0,0280694 ! amine transport GO:0015837 155 86 2,000 1,633E-03 0,02787033 ! regulation of DNA recombination GO:0000018 48 23 1,000 1,742E-03 0,02952304 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 1,742E-03 0,02931659 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! vesicle targeting GO:0006903 43 23 1,000 1,742E-03 0,029113 ! regulation of interleukin-6 production GO:0032675 29 23 1,000 1,742E-03 0,02891222 ! platelet activation GO:0030168 37 23 1,000 1,742E-03 0,02871419 ! negative regulation of catabolic process GO:0009895 50 23 1,000 1,742E-03 0,02851886 ! cellular respiration GO:0045333 135 88 2,000 1,745E-03 0,0283615 ! ATP biosynthetic process GO:0006754 159 88 2,000 1,745E-03 0,02817115 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,898E-03 0,03043615 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 1,898E-03 0,03023458 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 1,898E-03 0,03003567 ! regulation of tumor necrosis factor production GO:0032680 34 24 1,000 1,898E-03 0,02983936 ! carbohydrate biosynthetic process GO:0016051 141 93 2,000 2,043E-03 0,03192263 ! negative regulation of DNA replication GO:0008156 42 25 1,000 2,059E-03 0,03195983 ! receptor metabolic process GO:0043112 46 25 1,000 2,059E-03 0,03175496 ! response to starvation GO:0042594 42 25 1,000 2,059E-03 0,0315527 ! interaction with host GO:0051701 62 25 1,000 2,059E-03 0,031353 ! positive regulation of protein secretion GO:0050714 36 25 1,000 2,059E-03 0,03115581 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,059E-03 0,03096109 ! regulation of T cell activation GO:0050863 158 94 2,000 2,107E-03 0,03148064 ! regulation of interferon-gamma production GO:0032649 39 26 1,000 2,227E-03 0,03306942 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 2,227E-03 0,03286654 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,227E-03 0,03266613 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 2,227E-03 0,03246815 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 2,000 2,237E-03 0,03241999 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! regulation of DNA metabolic process GO:0051052 178 97 2,000 2,304E-03 0,03319038 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 2,000 2,304E-03 0,03299282 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 2,000 2,372E-03 0,03376825 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 2,401E-03 0,03397502 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 2,401E-03 0,03377634 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 1,000 2,401E-03 0,03357997 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,401E-03 0,03338586 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 2,581E-03 0,03568516 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 2,581E-03 0,03548125 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 2,581E-03 0,03527965 ! respiratory gaseous exchange GO:0007585 57 29 1,000 2,767E-03 0,03761331 ! immune response-activating signal transduction GO:0002757 47 29 1,000 2,767E-03 0,037402 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 2,767E-03 0,03719305 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 2,767E-03 0,03698642 ! acute-phase response GO:0006953 49 30 1,000 2,96E-03 0,03934081 ! ensheathment of neurons GO:0007272 57 30 1,000 2,96E-03 0,03912465 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 2,96E-03 0,03891086 ! regulation of B cell activation GO:0050864 50 30 1,000 2,96E-03 0,03869938 ! response to heat GO:0009408 50 30 1,000 2,96E-03 0,0384902 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 3,158E-03 0,04085231 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 3,158E-03 0,04063385 GO:0043433|negative regulation of transcription factor activity, ! regulation of axonogenesis GO:0050770 75 32 1,000 3,363E-03 0,04303726 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 3,363E-03 0,04280955 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 3,363E-03 0,04258423 ! gene silencing GO:0016458 65 32 1,000 3,363E-03 0,04236128 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 3,574E-03 0,04478141 ! leukocyte chemotaxis GO:0030595 50 33 1,000 3,574E-03 0,04454938 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 69 33 1,000 3,574E-03 0,04431974 ! establishment of vesicle localization GO:0051650 61 33 1,000 3,574E-03 0,04409246 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 3,79E-03 0,0465282 ! regulation of muscle development GO:0048634 70 35 1,000 4,013E-03 0,04901227 ! negative regulation of secretion GO:0051048 63 35 1,000 4,013E-03 0,04876473 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 4,013E-03 0,04851968 ! cytokine production GO:0001816 59 35 1,000 4,013E-03 0,04827708 ! vesicle localization GO:0051648 64 35 1,000 4,013E-03 0,0480369 ! maintenance of protein location in cell GO:0032507 86 36 1,000 4,242E-03 0,05052286 ! positive regulation of cell development GO:0010720 80 36 1,000 4,242E-03 0,05027398 ! DNA integrity checkpoint GO:0031570 75 36 1,000 4,242E-03 0,05002754 ! regulation of proteolysis GO:0030162 72 36 1,000 4,242E-03 0,0497835 ! negative regulation of cell activation GO:0050866 65 36 1,000 4,242E-03 0,04954184 ! negative regulation of DNA binding GO:0043392 68 37 1,000 4,476E-03 0,05202925 ! regulation of protein stability GO:0031647 73 37 1,000 4,476E-03 0,05177911 ! regulation of neuron projection development GO:0010975 91 38 1,000 4,717E-03 0,05429974 ! nucleotide catabolic process GO:0009166 61 38 1,000 4,717E-03 0,05404117 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 4,717E-03 0,05378505 ! mammary gland development GO:0030879 86 39 1,000 4,963E-03 0,05632695 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 4,963E-03 0,0560625 ! regulation of action potential in neuron GO:0019228 73 39 1,000 4,963E-03 0,05580053 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 5,215E-03 0,0583627 ! negative regulation of binding GO:0051100 72 40 1,000 5,215E-03 0,0580925 ! maintenance of protein location GO:0045185 91 40 1,000 5,215E-03 0,05782479 ! regulation of T cell proliferation GO:0042129 71 41 1,000 5,473E-03 0,06040627 ! regulation of T cell differentiation GO:0045580 70 41 1,000 5,473E-03 0,06013045 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 5,737E-03 0,06274091 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 5,737E-03 0,06245701 ! regulation of protein secretion GO:0050708 71 42 1,000 5,737E-03 0,06217567 ! activation of adenylate cyclase activity GO:0007190 91 44 1,000 6,281E-03 0,06777169 ! B cell differentiation GO:0030183 107 44 1,000 6,281E-03 0,06746914 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 6,562E-03 0,07017151 ! leukocyte migration GO:0050900 68 45 1,000 6,562E-03 0,06986101 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 6,562E-03 0,06955326 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 1,000 6,849E-03 0,0722703 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 6,849E-03 0,07195471 ! positive regulation of protein transport GO:0051222 72 46 1,000 6,849E-03 0,07164187 ! positive regulation of cyclase activity GO:0031281 103 47 1,000 7,141E-03 0,07437286 ! regulation of JNK cascade GO:0046328 94 47 1,000 7,141E-03 0,07405229 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 7,438E-03 0,07680694 ! positive regulation of lyase activity GO:0051349 104 48 1,000 7,438E-03 0,07647871 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 7,438E-03 0,07615327 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 7,438E-03 0,07583058 ! regulation of action potential GO:0001508 95 49 1,000 7,741E-03 0,07858741 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 7,741E-03 0,07825721 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 7,741E-03 0,07792977 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 7,741E-03 0,07760507 ! regulation of cell projection organization GO:0031344 121 50 1,000 8,05E-03 0,08036369 ! negative regulation of immune system process GO:0002683 95 50 1,000 8,05E-03 0,08003161 ! positive regulation of cytokine production GO:0001819 86 50 1,000 8,05E-03 0,07970226 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 8,364E-03 0,08247232 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 8,364E-03 0,08213569 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 90 52 1,000 8,683E-03 0,08492653 ! regulation of translational initiation GO:0006446 82 53 1,000 9,008E-03 0,08774746 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 9,008E-03 0,08739364 ! regulation of protein catabolic process GO:0042176 116 55 1,000 9,674E-03 0,09347693 ! aging GO:0007568 103 55 1,000 9,674E-03 0,09310302 ! regulation of DNA replication GO:0006275 101 56 1,000 0,01001498 0,09600018 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,0103612 0,09892483 ! positive regulation of secretion GO:0051047 95 59 1,000 0,01106939 0,10526857 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,01106939 0,10485413 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,01106939 0,10444293 ! establishment of organelle localization GO:0051656 109 59 1,000 0,01106939 0,10403495 ! regulation of heart contraction GO:0008016 110 60 1,000 0,01143129 0,10701822 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,01143129 0,10660342 ! detection of external stimulus GO:0009581 91 63 1,000 0,01254788 0,11656443 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,01254788 0,11611611 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,01293027 0,11919624 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,01293027 0,1187413 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,01293027 0,11828981 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0133763 0,12190671 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0133763 0,12144669 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0133763 0,12099012 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0133763 0,12053697 ! neuron fate determination GO:0048664 7 5 0,000 0,0133763 0,12008721 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0133763 0,11964079 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0133763 0,11919767 ! polyol transport GO:0015791 12 5 0,000 0,0133763 0,11875783 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0133763 0,11832122 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0133763 0,11788781 ! response to superoxide GO:0000303 10 5 0,000 0,0133763 0,11745756 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0133763 0,11703044 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0133763 0,11660642 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0133763 0,11618546 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0133763 0,11576753 ! female meiosis GO:0007143 7 5 0,000 0,0133763 0,11535259 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0133763 0,11494061 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0133763 0,11453157 ! cobalt ion transport GO:0006824 11 5 0,000 0,0133763 0,11412543 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0133763 0,11372216 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0133763 0,11332173 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0133763 0,11292411 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0133763 0,11252927 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0133763 0,11213719 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0133763 0,11174782 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0133763 0,11136115 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0133763 0,11097715 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0133763 0,11059578 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0133763 0,11021703 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0133763 0,10984086 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0133763 0,10946725 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,0133763 0,10909618 ! negative chemotaxis GO:0050919 14 5 0,000 0,0133763 0,10872761 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0133763 0,10836152 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0133763 0,10799789 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0133763 0,1076367 ! behavioral response to pain GO:0048266 9 5 0,000 0,0133763 0,10727791 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0133763 0,1069215 ! Notch receptor processing GO:0007220 8 5 0,000 0,0133763 0,10656746 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0133763 0,10621575 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0133763 0,10586636 ! micturition GO:0060073 9 5 0,000 0,0133763 0,10551925 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0133763 0,10517442 ! copulation GO:0007620 9 5 0,000 0,0133763 0,10483183 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0133763 0,10449147 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0133763 0,10415331 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0133763 0,10381733 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0133763 0,10348351 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0133763 0,10315183 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0133763 0,10282228 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0133763 0,10249482 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0133763 0,10216944 ! grooming behavior GO:0007625 6 5 0,000 0,0133763 0,10184611 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0133763 0,10152483 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0133763 0,10120557 ! response to protozoan GO:0001562 10 5 0,000 0,0133763 0,10088831 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,0133763 0,10057304 ! lymph vessel development GO:0001945 10 5 0,000 0,0133763 0,10025973 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0133763 0,09994836 ! endochondral ossification GO:0001958 16 5 0,000 0,0133763 0,09963892 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0133763 0,0993314 ! parathyroid gland development GO:0060017 13 5 0,000 0,0133763 0,09902576 ! anagen GO:0042640 6 5 0,000 0,0133763 0,098722 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0133763 0,0984201 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0133763 0,09812004 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0133763 0,0978218 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0133763 0,09752537 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0133763 0,09723073 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0133763 0,09693787 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0133763 0,09664676 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0133763 0,0963574 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0133763 0,09606977 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0133763 0,09578385 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0133763 0,09549962 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0133763 0,09521708 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0133763 0,0949362 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0133763 0,09465698 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0133763 0,09437939 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0133763 0,09410343 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,0133763 0,09382907 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0133763 0,09355631 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0133763 0,09328514 ! histidine catabolic process GO:0006548 6 5 0,000 0,0133763 0,09301553 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0133763 0,09274747 ! valine metabolic process GO:0006573 10 5 0,000 0,0133763 0,09248095 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0133763 0,09221597 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0133763 0,09195249 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0133763 0,09169052 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0133763 0,09143003 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0133763 0,09117103 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0133763 0,09091348 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0133763 0,09065739 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0133763 0,09040273 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0133763 0,0901495 ! muscle cell migration GO:0014812 8 5 0,000 0,0133763 0,08989769 ! mitochondrial fission GO:0000266 8 5 0,000 0,0133763 0,08964728 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0133763 0,08939826 ! mRNA transcription GO:0009299 9 5 0,000 0,0133763 0,08915062 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0133763 0,08890434 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0133763 0,08865943 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0133763 0,08841586 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0133763 0,08817362 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0133763 0,08793271 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0133763 0,08769311 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0133763 0,08745482 ! response to food GO:0032094 6 5 0,000 0,0133763 0,08721781 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0133763 0,08698209 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0133763 0,08674763 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0133763 0,08651444 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0133763 0,0862825 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0133763 0,0860518 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,0133763 0,08582233 ! forebrain neuron development GO:0021884 13 5 0,000 0,0133763 0,08559407 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0133763 0,08536704 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0133763 0,0851412 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0133763 0,08491655 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0133763 0,08469308 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0133763 0,08447079 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0133763 0,08424967 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0133763 0,08402969 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0133763 0,08381087 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0133763 0,08359317 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0133763 0,08337661 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0133763 0,08316117 ! basic amino acid transport GO:0015802 11 5 0,000 0,0133763 0,08294684 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0133763 0,0827336 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,0133763 0,08252147 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0133763 0,08231041 ! depyrimidination GO:0045008 10 5 0,000 0,0133763 0,08210044 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0133763 0,08189153 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0133763 0,08168369 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0133763 0,08147689 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0133763 0,08127114 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,0133763 0,08106643 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0133763 0,08086274 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0133763 0,08066008 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0133763 0,08045843 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0133763 0,08025779 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0133763 0,08005814 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0133763 0,07985948 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0133763 0,07966181 ! response to arsenic GO:0046685 10 5 0,000 0,0133763 0,07946512 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0133763 0,07926939 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0133763 0,07907462 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0133763 0,07888081 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0133763 0,07868795 ! response to cadmium ion GO:0046686 7 5 0,000 0,0133763 0,07849603 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0133763 0,07830504 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0133763 0,07811498 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0133763 0,07792584 ! decidualization GO:0046697 11 5 0,000 0,0133763 0,07773761 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0133763 0,07755029 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0133763 0,07736388 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0133763 0,07717835 ! protein autoprocessing GO:0016540 7 5 0,000 0,0133763 0,07699371 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0133763 0,07680996 ! neural tube patterning GO:0021532 7 5 0,000 0,0133763 0,07662708 ! embryonic cleavage GO:0040016 6 5 0,000 0,0133763 0,07644506 ! peroxisome fission GO:0016559 5 5 0,000 0,0133763 0,07626392 ! histone demethylation GO:0016577 10 5 0,000 0,0133763 0,07608362 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0133763 0,07590418 ! mitotic recombination GO:0006312 9 5 0,000 0,0133763 0,07572558 ! metaphase plate congression GO:0051310 7 5 0,000 0,0133763 0,07554782 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0133763 0,0753709 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0133763 0,07519479 ! enteric nervous system development GO:0048484 8 5 0,000 0,0133763 0,07501952 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0133763 0,07484505 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0133763 0,0746714 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0133763 0,07449855 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0133763 0,07432649 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0133763 0,07415524 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0133763 0,07398476 ! plasminogen activation GO:0031639 5 5 0,000 0,0133763 0,07381507 ! B cell homeostasis GO:0001782 13 5 0,000 0,0133763 0,07364616 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0133763 0,07347802 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0133763 0,07331064 ! metaphase GO:0051323 8 5 0,000 0,0133763 0,07314403 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0133763 0,07297817 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0133763 0,07281306 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0133763 0,0726487 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0133763 0,07248507 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0133763 0,07232218 GO:0015991|ATP hydrolysis coupled proton transport, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0133763 0,07216003 ! response to redox state GO:0051775 5 5 0,000 0,0133763 0,0719986 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0133763 0,07183788 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0133763 0,07167789 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0133763 0,0715186 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0133763 0,07136003 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0133763 0,07120215 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0133763 0,07104497 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0133763 0,07088849 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0133763 0,07073269 ! striatum development GO:0021756 9 5 0,000 0,0133763 0,07057757 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0133763 0,07042313 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0133763 0,07026937 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0133763 0,07011628 ! glial cell migration GO:0008347 11 5 0,000 0,0133763 0,06996385 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0133763 0,06981209 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0133763 0,06966098 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0133763 0,06951052 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0133763 0,06936072 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0133763 0,06921155 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0133763 0,06906303 ! neuroprotection GO:0043526 6 5 0,000 0,0133763 0,06891514 ! neural plate development GO:0001840 8 5 0,000 0,0133763 0,06876789 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0133763 0,06862126 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0133763 0,06847526 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0133763 0,06832988 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0133763 0,06818511 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0133763 0,06804096 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0133763 0,06789741 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0133763 0,06775447 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0133763 0,06761213 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0133763 0,06747038 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0133763 0,06732923 ! spindle assembly GO:0051225 6 5 0,000 0,0133763 0,06718867 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0133763 0,06704869 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0133763 0,0669093 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 6 5 0,000 0,0133763 0,06677048 ! stem cell division GO:0017145 11 5 0,000 0,0133763 0,06663224 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0133763 0,06649457 ! organ regeneration GO:0031100 7 5 0,000 0,0133763 0,06635747 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0133763 0,06622093 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0133763 0,06608495 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0133763 0,06594953 ! cell projection assembly GO:0030031 120 66 1,000 0,01371016 0,06745737 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,01410761 0,06927125 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01410761 0,06913017 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01410761 0,06898966 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,01410761 0,06884972 ! activation of immune response GO:0002253 105 67 1,000 0,01410761 0,06871035 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,01451002 0,0705275 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,01491736 0,07236124 ! respiratory tube development GO:0030323 150 70 1,000 0,01532961 0,07421134 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,01574673 0,07607757 ! regulation of immune effector process GO:0002697 137 71 1,000 0,01574673 0,07592511 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01603027 0,07713768 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01603027 0,07698371 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01603027 0,07683035 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01603027 0,07667761 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01603027 0,07652547 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01603027 0,07637394 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01603027 0,076223 ! sleep GO:0030431 13 6 0,000 0,01603027 0,07607266 ! response to oxygen radical GO:0000305 11 6 0,000 0,01603027 0,07592291 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01603027 0,07577375 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01603027 0,07562517 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01603027 0,07547718 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01603027 0,07532976 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01603027 0,07518292 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01603027 0,07503665 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01603027 0,07489095 ! forebrain regionalization GO:0021871 8 6 0,000 0,01603027 0,07474581 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01603027 0,07460123 ! male meiosis GO:0007140 7 6 0,000 0,01603027 0,07445722 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01603027 0,07431375 ! response to zinc ion GO:0010043 9 6 0,000 0,01603027 0,07417084 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01603027 0,07402848 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01603027 0,07388666 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01603027 0,07374539 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01603027 0,07360465 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01603027 0,07346445 ! malate metabolic process GO:0006108 11 6 0,000 0,01603027 0,07332479 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01603027 0,07318565 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01603027 0,07304704 ! protein refolding GO:0042026 15 6 0,000 0,01603027 0,07290896 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01603027 0,07277139 ! opsonization GO:0008228 8 6 0,000 0,01603027 0,07263435 ! mating behavior GO:0007617 7 6 0,000 0,01603027 0,07249782 ! neuron remodeling GO:0016322 15 6 0,000 0,01603027 0,0723618 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01603027 0,07222629 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01603027 0,07209129 ! equilibrioception GO:0050957 14 6 0,000 0,01603027 0,07195679 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01603027 0,07182279 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01603027 0,07168929 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01603027 0,07155629 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01603027 0,07142377 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01603027 0,07129175 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01603027 0,07116022 ! toxin metabolic process GO:0009404 11 6 0,000 0,01603027 0,07102917 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01603027 0,0708986 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01603027 0,07076851 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01603027 0,0706389 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01603027 0,07050976 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01603027 0,07038109 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01603027 0,07025289 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01603027 0,07012516 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01603027 0,06999789 ! thymic T cell selection GO:0045061 12 6 0,000 0,01603027 0,06987108 ! protein lipoylation GO:0009249 10 6 0,000 0,01603027 0,06974473 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01603027 0,06961884 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01603027 0,0694934 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01603027 0,06936841 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01603027 0,06924387 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01603027 0,06911978 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01603027 0,06899613 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01603027 0,06887293 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01603027 0,06875016 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01603027 0,06862783 ! hyperosmotic response GO:0006972 9 6 0,000 0,01603027 0,06850593 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01603027 0,06838446 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01603027 0,06826343 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01603027 0,06814282 ! urea metabolic process GO:0019627 7 6 0,000 0,01603027 0,06802264 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01603027 0,06790288 ! neutrophil activation GO:0042119 8 6 0,000 0,01603027 0,06778355 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01603027 0,06766463 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01603027 0,06754613 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01603027 0,06742804 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01603027 0,06731036 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01603027 0,0671931 ! neuron apoptosis GO:0051402 9 6 0,000 0,01603027 0,06707624 ! nucleoside salvage GO:0043174 9 6 0,000 0,01603027 0,06695979 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01603027 0,06684374 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01603027 0,06672809 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01603027 0,06661285 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01603027 0,066498 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01603027 0,06638354 ! carnitine transport GO:0015879 10 6 0,000 0,01603027 0,06626948 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01603027 0,06615581 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01603027 0,06604253 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01603027 0,06592964 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01603027 0,06581713 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01603027 0,06570501 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01603027 0,06559326 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01603027 0,0654819 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01603027 0,06537091 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01603027 0,0652603 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01603027 0,06515006 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01603027 0,0650402 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01603027 0,0649307 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01603027 0,06482158 ! neural nucleus development GO:0048857 14 6 0,000 0,01603027 0,06471282 ! response to UV-C GO:0010225 11 6 0,000 0,01603027 0,06460442 ! astrocyte development GO:0014002 15 6 0,000 0,01603027 0,06449638 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01603027 0,06438871 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01603027 0,0642814 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01603027 0,06417444 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01603027 0,06406784 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01603027 0,06396159 ! response to copper ion GO:0046688 10 6 0,000 0,01603027 0,06385569 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01603027 0,06375015 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01603027 0,06364495 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01603027 0,0635401 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01603027 0,06343559 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01603027 0,06333143 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01603027 0,0632276 ! hair follicle maturation GO:0048820 7 6 0,000 0,01603027 0,06312412 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01603027 0,06302098 ! Schwann cell development GO:0014044 15 6 0,000 0,01603027 0,06291817 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01603027 0,0628157 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01603027 0,06271356 ! subpallium development GO:0021544 10 6 0,000 0,01603027 0,06261175 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01603027 0,06251027 ! histone ubiquitination GO:0016574 8 6 0,000 0,01603027 0,06240912 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01603027 0,0623083 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01603027 0,0622078 ! G2 phase GO:0051319 16 6 0,000 0,01603027 0,06210763 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01603027 0,06200778 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01603027 0,06190825 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01603027 0,06180904 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01603027 0,06171014 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01603027 0,06161156 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01603027 0,0615133 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01603027 0,06141535 ! receptor internalization GO:0031623 10 6 0,000 0,01603027 0,06131771 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01603027 0,06122038 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01603027 0,06112336 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01603027 0,06102664 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01603027 0,06093023 ! protein deubiquitination GO:0016579 14 6 0,000 0,01603027 0,06083413 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01603027 0,06073833 ! protein destabilization GO:0031648 9 6 0,000 0,01603027 0,06064283 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01603027 0,06054763 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01603027 0,06045272 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01603027 0,06035812 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01603027 0,06026381 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01603027 0,06016979 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01603027 0,06007607 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01603027 0,05998264 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01603027 0,0598895 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01603027 0,05979665 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01603027 0,05970408 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01603027 0,05961181 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01603027 0,05951981 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01603027 0,0594281 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01603027 0,05933667 ! catecholamine transport GO:0051937 9 6 0,000 0,01603027 0,05924553 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01603027 0,05915466 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01603027 0,05906407 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01603027 0,05897376 ! maternal placenta development GO:0001893 12 6 0,000 0,01603027 0,05888372 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01603027 0,05879396 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01603027 0,05870447 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01603027 0,05861526 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01603027 0,05852631 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01603027 0,05843763 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01603027 0,05834923 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01603027 0,05826108 ! acute inflammatory response GO:0002526 113 72 1,000 0,0161687 0,05867554 ! axon guidance GO:0007411 139 73 1,000 0,01659548 0,06013363 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01702706 0,06160466 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,01702706 0,06151216 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,01746339 0,06299389 ! defense response to bacterium GO:0042742 89 76 1,000 0,01790446 0,06448823 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,01790446 0,06439184 ! regulation of catabolic process GO:0009894 161 76 1,000 0,01790446 0,06429573 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01835024 0,06579832 ! tRNA transcription GO:0009304 14 7 0,000 0,0186772 0,06687104 ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,0186772 0,06677168 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0186772 0,06667261 ! regulation of helicase activity GO:0051095 15 7 0,000 0,0186772 0,06657384 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,0186772 0,06647535 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,0186772 0,06637716 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0186772 0,06627926 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,0186772 0,06618165 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0186772 0,06608432 ! prostate gland development GO:0030850 13 7 0,000 0,0186772 0,06598728 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,0186772 0,06589053 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0186772 0,06579405 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0186772 0,06569786 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,0186772 0,06560195 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0186772 0,06550632 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,0186772 0,06541097 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,0186772 0,0653159 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,0186772 0,0652211 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,0186772 0,06512658 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0186772 0,06503233 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,0186772 0,06493835 ! glycolipid transport GO:0046836 10 7 0,000 0,0186772 0,06484464 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0186772 0,06475121 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,0186772 0,06465804 ! neuron adhesion GO:0007158 12 7 0,000 0,0186772 0,06456514 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,0186772 0,06447251 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0186772 0,06438014 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,0186772 0,06428804 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0186772 0,0641962 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,0186772 0,06410462 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,0186772 0,0640133 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,0186772 0,06392225 ! mRNA stabilization GO:0048255 18 7 0,000 0,0186772 0,06383145 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,0186772 0,06374091 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,0186772 0,06365062 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,0186772 0,06356059 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,0186772 0,06347082 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0186772 0,0633813 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,0186772 0,06329203 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0186772 0,06320301 ! lipoprotein transport GO:0042953 14 7 0,000 0,0186772 0,06311424 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0186772 0,06302572 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0186772 0,06293745 ! rhythmic behavior GO:0007622 15 7 0,000 0,0186772 0,06284942 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,0186772 0,06276165 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,0186772 0,06267411 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,0186772 0,06258682 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0186772 0,06249978 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0186772 0,06241297 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,0186772 0,06232641 ! mechanosensory behavior GO:0007638 14 7 0,000 0,0186772 0,06224008 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,0186772 0,062154 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0186772 0,06206815 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,0186772 0,06198254 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0186772 0,06189716 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0186772 0,06181202 ! spinal cord patterning GO:0021511 13 7 0,000 0,0186772 0,06172711 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,0186772 0,06164244 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0186772 0,061558 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,0186772 0,06147379 ! adrenal gland development GO:0030325 17 7 0,000 0,0186772 0,06138981 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,0186772 0,06130606 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,0186772 0,06122253 ! ovulation GO:0030728 9 7 0,000 0,0186772 0,06113924 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,0186772 0,06105617 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,0186772 0,06097332 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 20 7 0,000 0,0186772 0,0608907 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0186772 0,06080831 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0186772 0,06072613 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,0186772 0,06064418 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,0186772 0,06056245 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,0186772 0,06048094 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0186772 0,06039965 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0186772 0,06031858 ! galactose metabolic process GO:0006012 13 7 0,000 0,0186772 0,06023772 ! vesicle fusion GO:0006906 17 7 0,000 0,0186772 0,06015708 ! response to dietary excess GO:0002021 8 7 0,000 0,0186772 0,06007666 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0186772 0,05999645 ! intracellular pH reduction GO:0051452 11 7 0,000 0,0186772 0,05991645 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0186772 0,05983667 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,0186772 0,0597571 ! organ growth GO:0035265 15 7 0,000 0,0186772 0,05967774 ! purine salvage GO:0043101 10 7 0,000 0,0186772 0,05959859 ! nucleoside transport GO:0015858 8 7 0,000 0,0186772 0,05951965 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,0186772 0,05944092 ! parturition GO:0007567 14 7 0,000 0,0186772 0,0593624 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,0186772 0,05928409 ! rRNA modification GO:0000154 14 7 0,000 0,0186772 0,05920598 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,0186772 0,05912808 ! spindle checkpoint GO:0031577 15 7 0,000 0,0186772 0,05905038 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,0186772 0,05897289 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,0186772 0,05889559 ! macrophage differentiation GO:0030225 11 7 0,000 0,0186772 0,05881851 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0186772 0,05874162 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0186772 0,05866493 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,0186772 0,05858845 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,0186772 0,05851216 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,0186772 0,05843607 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0186772 0,05836018 ! fibrinolysis GO:0042730 10 7 0,000 0,0186772 0,05828449 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,0186772 0,05820899 ! eating behavior GO:0042755 7 7 0,000 0,0186772 0,05813369 ! B cell lineage commitment GO:0002326 21 7 0,000 0,0186772 0,05805858 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0186772 0,05798366 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,0186772 0,05790894 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0186772 0,05783441 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,0186772 0,05776008 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0186772 0,05768593 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,0186772 0,05761197 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,0186772 0,05753821 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,0186772 0,05746463 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,0186772 0,05739124 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0186772 0,05731803 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,0186772 0,05724502 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0186772 0,05717219 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0186772 0,05709954 ! regulation of meiosis GO:0040020 12 7 0,000 0,0186772 0,05702708 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,0186772 0,0569548 ! T cell lineage commitment GO:0002360 16 7 0,000 0,0186772 0,05688271 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,0186772 0,05681079 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0186772 0,05673906 ! oxygen homeostasis GO:0032364 12 7 0,000 0,0186772 0,05666751 ! transcription termination GO:0006353 13 7 0,000 0,0186772 0,05659614 ! response to tumor cell GO:0002347 13 7 0,000 0,0186772 0,05652495 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,0186772 0,05645394 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0186772 0,05638311 ! anaphase GO:0051322 17 7 0,000 0,0186772 0,05631245 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,0186772 0,05624198 ! axonal fasciculation GO:0007413 18 7 0,000 0,0186772 0,05617167 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,0186772 0,05610155 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,0186772 0,05603159 ! diuresis GO:0030146 12 7 0,000 0,0186772 0,05596182 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0186772 0,05589221 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0186772 0,05582278 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0186772 0,05575352 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,0186772 0,05568443 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,0186772 0,05561552 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0186772 0,05554677 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0186772 0,0554782 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0186772 0,05540979 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,0186772 0,05534155 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0186772 0,05527348 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,0186772 0,05520558 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0186772 0,05513784 ! lymph node development GO:0048535 10 7 0,000 0,0186772 0,05507027 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,0186772 0,05500286 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0186772 0,05493562 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,0186772 0,05486855 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,0186772 0,05480163 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,0186772 0,05473488 ! adult feeding behavior GO:0008343 9 7 0,000 0,0186772 0,0546683 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,0186772 0,05460187 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,0186772 0,05453561 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0186772 0,0544695 ! muscle adaptation GO:0043500 14 7 0,000 0,0186772 0,05440356 ! embryonic heart tube development GO:0035050 10 7 0,000 0,0186772 0,05433777 ! retina homeostasis GO:0001895 12 7 0,000 0,0186772 0,05427215 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,0186772 0,05420668 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,0186772 0,05414137 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,0186772 0,05407622 ! protein prenylation GO:0018342 18 7 0,000 0,0186772 0,05401122 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,0186772 0,05394639 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,0186772 0,0538817 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0186772 0,05381717 ! protein oligomerization GO:0051259 139 78 1,000 0,01880069 0,05410821 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,0192558 0,05535178 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,01971552 0,05660566 ! T cell activation GO:0042110 168 81 1,000 0,02017984 0,05786972 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,02017984 0,05780083 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,02064873 0,05907354 ! response to nutrient GO:0007584 125 82 1,000 0,02064873 0,05900338 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,02064873 0,05893338 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,02064873 0,05886356 ! regulation of lyase activity GO:0051339 160 83 1,000 0,02112216 0,06014191 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02131709 0,0606252 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02131709 0,06055362 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,02131709 0,06048222 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02131709 0,06041098 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02131709 0,0603399 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02131709 0,060269 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02131709 0,06019826 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02131709 0,06012769 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02131709 0,06005728 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02131709 0,05998704 ! meiotic prophase I GO:0007128 13 8 0,000 0,02131709 0,05991696 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02131709 0,05984705 ! oligopeptide transport GO:0006857 15 8 0,000 0,02131709 0,05977729 ! UTP metabolic process GO:0046051 8 8 0,000 0,02131709 0,05970771 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02131709 0,05963828 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02131709 0,05956901 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02131709 0,05949991 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02131709 0,05943096 ! succinate metabolic process GO:0006105 14 8 0,000 0,02131709 0,05936217 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02131709 0,05929355 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02131709 0,05922508 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02131709 0,05915677 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02131709 0,05908862 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02131709 0,05902062 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02131709 0,05895278 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02131709 0,0588851 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02131709 0,05881757 ! reflex GO:0060004 16 8 0,000 0,02131709 0,05875019 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02131709 0,05868297 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02131709 0,05861591 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02131709 0,05854899 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02131709 0,05848223 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02131709 0,05841563 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02131709 0,05834917 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02131709 0,05828286 ! pigment granule organization GO:0048753 16 8 0,000 0,02131709 0,05821671 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02131709 0,0581507 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02131709 0,05808485 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02131709 0,05801914 ! histidine metabolic process GO:0006547 16 8 0,000 0,02131709 0,05795358 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02131709 0,05788817 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02131709 0,05782291 ! glycine catabolic process GO:0006546 13 8 0,000 0,02131709 0,05775779 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02131709 0,05769282 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02131709 0,057628 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,02131709 0,05756332 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02131709 0,05749879 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02131709 0,0574344 ! melanin metabolic process GO:0006582 15 8 0,000 0,02131709 0,05737016 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02131709 0,05730605 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02131709 0,0572421 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02131709 0,05717828 ! macrophage activation GO:0042116 12 8 0,000 0,02131709 0,05711461 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02131709 0,05705108 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02131709 0,05698769 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02131709 0,05692444 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02131709 0,05686133 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02131709 0,05679836 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02131709 0,05673553 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02131709 0,05667284 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02131709 0,05661029 ! osteoblast development GO:0002076 16 8 0,000 0,02131709 0,05654787 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02131709 0,05648559 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02131709 0,05642345 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02131709 0,05636145 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02131709 0,05629958 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02131709 0,05623785 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02131709 0,05617625 ! response to UV-B GO:0010224 16 8 0,000 0,02131709 0,05611479 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02131709 0,05605346 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02131709 0,05599227 ! intermediate filament organization GO:0045109 12 8 0,000 0,02131709 0,05593121 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02131709 0,05587028 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02131709 0,05580949 ! cellular extravasation GO:0045123 12 8 0,000 0,02131709 0,05574882 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02131709 0,05568829 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02131709 0,05562789 ! response to antibiotic GO:0046677 11 8 0,000 0,02131709 0,05556763 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02131709 0,05550749 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02131709 0,05544748 ! DNA topological change GO:0006265 12 8 0,000 0,02131709 0,0553876 ! response to tropane GO:0014073 15 8 0,000 0,02131709 0,05532785 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02131709 0,05526823 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02131709 0,05520874 ! melanosome transport GO:0032402 13 8 0,000 0,02131709 0,05514938 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,02131709 0,05509014 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02131709 0,05503103 ! mast cell activation GO:0045576 14 8 0,000 0,02131709 0,05497205 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02131709 0,05491319 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02131709 0,05485446 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02131709 0,05479585 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02131709 0,05473737 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02131709 0,05467902 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02131709 0,05462079 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02131709 0,05456268 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02131709 0,0545047 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02131709 0,05444684 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02131709 0,0543891 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02131709 0,05433148 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02131709 0,05427399 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02131709 0,05421662 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02131709 0,05415937 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02131709 0,05410223 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02131709 0,05404523 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02131709 0,05398834 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02131709 0,05393157 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02131709 0,05387491 ! hormone catabolic process GO:0042447 17 8 0,000 0,02131709 0,05381838 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02131709 0,05376197 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02131709 0,05370567 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02131709 0,0536495 ! ATP catabolic process GO:0006200 11 8 0,000 0,02131709 0,05359344 ! blastocyst growth GO:0001832 19 8 0,000 0,02131709 0,05353749 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02131709 0,05348167 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02131709 0,05342596 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02131709 0,05337036 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02131709 0,05331488 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02131709 0,05325952 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02131709 0,05320427 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02131709 0,05314914 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02131709 0,05309412 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02131709 0,05303921 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02131709 0,05298442 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02131709 0,05292974 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02131709 0,05287517 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02131709 0,05282072 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02131709 0,05276638 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02131709 0,05271215 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,0216001 0,05335712 ! negative regulation of transport GO:0051051 153 84 1,000 0,0216001 0,0533024 ! response to unfolded protein GO:0006986 131 85 1,000 0,02208253 0,05443705 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,02208253 0,05438133 GO:0002696|positive regulation of leukocyte activation, ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,02306073 0,05673223 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of protein transport GO:0051223 154 87 1,000 0,02306073 0,05667428 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,02355646 0,0578335 ! gland development GO:0048732 206 88 1,000 0,02355646 0,05777455 ! regulation of developmental growth GO:0048638 15 9 0,000 0,02394997 0,05867986 ! axon extension GO:0048675 15 9 0,000 0,02394997 0,05862017 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02394997 0,05856059 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02394997 0,05850114 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02394997 0,05844181 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02394997 0,0583826 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02394997 0,0583235 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02394997 0,05826453 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02394997 0,05820568 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02394997 0,05814695 ! phosphate transport GO:0006817 19 9 0,000 0,02394997 0,05808833 ! reproductive behavior GO:0019098 19 9 0,000 0,02394997 0,05802983 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02394997 0,05797145 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02394997 0,05791319 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02394997 0,05785504 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02394997 0,05779701 ! GTP metabolic process GO:0046039 9 9 0,000 0,02394997 0,0577391 ! RNA methylation GO:0001510 15 9 0,000 0,02394997 0,0576813 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02394997 0,05762362 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02394997 0,05756606 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02394997 0,05750861 ! artery development GO:0060840 24 9 0,000 0,02394997 0,05745127 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02394997 0,05739405 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02394997 0,05733694 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02394997 0,05727994 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02394997 0,05722306 ! chemosensory behavior GO:0007635 20 9 0,000 0,02394997 0,05716629 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02394997 0,05710964 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02394997 0,05705309 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02394997 0,05699666 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02394997 0,05694034 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02394997 0,05688413 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02394997 0,05682803 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02394997 0,05677204 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02394997 0,05671616 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02394997 0,0566604 ! protein targeting to ER GO:0045047 22 9 0,000 0,02394997 0,05660474 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02394997 0,05654919 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02394997 0,05649375 ! T cell selection GO:0045058 23 9 0,000 0,02394997 0,05643842 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02394997 0,05638319 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02394997 0,05632808 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02394997 0,05627307 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02394997 0,05621817 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02394997 0,05616337 ! mannose metabolic process GO:0006013 13 9 0,000 0,02394997 0,05610869 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02394997 0,05605411 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02394997 0,05599963 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02394997 0,05594526 ! receptor clustering GO:0043113 18 9 0,000 0,02394997 0,055891 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02394997 0,05583684 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02394997 0,05578279 ! ruffle organization GO:0031529 15 9 0,000 0,02394997 0,05572884 ! retinol metabolic process GO:0042572 18 9 0,000 0,02394997 0,055675 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02394997 0,05562126 ! behavioral fear response GO:0001662 22 9 0,000 0,02394997 0,05556762 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02394997 0,05551409 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02394997 0,05546066 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02394997 0,05540733 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02394997 0,0553541 ! protein heterooligomerization GO:0051291 16 9 0,000 0,02394997 0,05530098 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02394997 0,05524796 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02394997 0,05519504 ! segment specification GO:0007379 13 9 0,000 0,02394997 0,05514222 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02394997 0,05508951 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02394997 0,05503689 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02394997 0,05498437 ! response to amine stimulus GO:0014075 13 9 0,000 0,02394997 0,05493196 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02394997 0,05487964 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02394997 0,05482742 ! erythrocyte development GO:0048821 15 9 0,000 0,02394997 0,05477531 ! gas homeostasis GO:0033483 16 9 0,000 0,02394997 0,05472329 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02394997 0,05467137 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02394997 0,05461955 ! renal water homeostasis GO:0003091 14 9 0,000 0,02394997 0,05456782 ! postreplication repair GO:0006301 22 9 0,000 0,02394997 0,0545162 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02394997 0,05446467 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02394997 0,05441324 ! icosanoid secretion GO:0032309 15 9 0,000 0,02394997 0,05436191 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02394997 0,05431067 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02394997 0,05425953 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02394997 0,05420849 ! regulation of cell division GO:0051302 15 9 0,000 0,02394997 0,05415754 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02394997 0,05410669 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02394997 0,05405593 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02394997 0,05400527 ! sterol catabolic process GO:0016127 11 9 0,000 0,02394997 0,0539547 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02394997 0,05390423 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02394997 0,05385385 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02394997 0,05380357 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02394997 0,05375338 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02394997 0,05370328 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02394997 0,05365328 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02394997 0,05360337 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02394997 0,05355355 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02394997 0,05350383 ! purine base metabolic process GO:0006144 21 9 0,000 0,02394997 0,0534542 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02394997 0,05340465 ! pigment granule transport GO:0051904 17 9 0,000 0,02394997 0,05335521 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02394997 0,05330585 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02394997 0,05325658 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02394997 0,05320741 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02394997 0,05315832 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,02405656 0,0533457 ! ossification GO:0001503 188 90 1,000 0,02456101 0,05441418 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,02456101 0,05436412 ! bone development GO:0060348 189 91 1,000 0,02506979 0,05543927 ! response to protein stimulus GO:0051789 149 91 1,000 0,02506979 0,05538836 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,02610023 0,05761207 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,02610023 0,05755926 ! regulation of membrane potential GO:0042391 164 93 1,000 0,02610023 0,05750655 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02657585 0,05850091 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02657585 0,05844744 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02657585 0,05839406 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02657585 0,05834078 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02657585 0,0582876 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02657585 0,05823451 ! synapsis GO:0007129 13 10 0,000 0,02657585 0,05818152 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02657585 0,05812863 ! N-glycan processing GO:0006491 20 10 0,000 0,02657585 0,05807584 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02657585 0,05802313 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02657585 0,05797053 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02657585 0,05791802 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02657585 0,05786561 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02657585 0,05781329 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02657585 0,05776106 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02657585 0,05770893 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02657585 0,05765689 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02657585 0,05760495 ! androgen metabolic process GO:0008209 17 10 0,000 0,02657585 0,0575531 ! phospholipid efflux GO:0033700 16 10 0,000 0,02657585 0,05750134 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02657585 0,05744968 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02657585 0,05739811 ! lung alveolus development GO:0048286 26 10 0,000 0,02657585 0,05734663 ! pathogenesis GO:0009405 13 10 0,000 0,02657585 0,05729525 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02657585 0,05724395 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02657585 0,05719275 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02657585 0,05714164 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02657585 0,05709062 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02657585 0,05703969 ! endoderm development GO:0007492 16 10 0,000 0,02657585 0,05698885 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02657585 0,05693811 ! arginine catabolic process GO:0006527 13 10 0,000 0,02657585 0,05688745 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02657585 0,05683688 ! proline metabolic process GO:0006560 13 10 0,000 0,02657585 0,05678641 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02657585 0,05673602 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02657585 0,05668572 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02657585 0,05663551 ! V(D)J recombination GO:0033151 28 10 0,000 0,02657585 0,05658539 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02657585 0,05653536 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02657585 0,05648542 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02657585 0,05643556 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02657585 0,0563858 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02657585 0,05633612 ! multicellular organism growth GO:0035264 18 10 0,000 0,02657585 0,05628653 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02657585 0,05623702 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02657585 0,0561876 ! epithelial cell development GO:0002064 20 10 0,000 0,02657585 0,05613827 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02657585 0,05608903 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02657585 0,05603987 ! macroautophagy GO:0016236 17 10 0,000 0,02657585 0,0559908 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02657585 0,05594181 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02657585 0,05589291 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02657585 0,0558441 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02657585 0,05579537 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02657585 0,05574673 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02657585 0,05569817 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02657585 0,05564969 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02657585 0,0556013 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02657585 0,05555299 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02657585 0,05550477 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02657585 0,05545663 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02657585 0,05540857 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02657585 0,0553606 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02657585 0,05531271 ! DNA ligation GO:0006266 19 10 0,000 0,02657585 0,0552649 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02657585 0,05521718 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02657585 0,05516954 ! melanosome localization GO:0032400 16 10 0,000 0,02657585 0,05512198 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02657585 0,0550745 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02657585 0,0550271 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02657585 0,05497979 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02657585 0,05493256 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02657585 0,0548854 ! mRNA cleavage GO:0006379 17 10 0,000 0,02657585 0,05483833 ! protein sumoylation GO:0016925 15 10 0,000 0,02657585 0,05479134 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02657585 0,05474443 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02657585 0,0546976 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02657585 0,05465085 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02657585 0,05460418 ! salivary gland development GO:0007431 27 10 0,000 0,02657585 0,05455759 ! prophase GO:0051324 15 10 0,000 0,02657585 0,05451108 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02657585 0,05446465 ! apical protein localization GO:0045176 15 10 0,000 0,02657585 0,05441829 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02657585 0,05437202 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02657585 0,05432582 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02657585 0,05427971 ! midbrain development GO:0030901 13 10 0,000 0,02657585 0,05423367 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02657585 0,05418771 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02657585 0,05414182 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02657585 0,05409602 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02657585 0,05405029 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02657585 0,05400464 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02657585 0,05395907 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02657585 0,05391357 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02657585 0,05386815 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02657585 0,05382281 ! oocyte development GO:0048599 17 10 0,000 0,02657585 0,05377754 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02657585 0,05373235 ! blastocyst formation GO:0001825 17 10 0,000 0,02657585 0,05368723 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02657585 0,05364219 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02657585 0,05359723 ! activation of innate immune response GO:0002218 12 10 0,000 0,02657585 0,05355234 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02657585 0,05350753 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02657585 0,05346279 ! response to nicotine GO:0035094 20 10 0,000 0,02657585 0,05341812 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02657585 0,05337353 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02657585 0,05332902 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02657585 0,05328458 ! localization within membrane GO:0051668 20 10 0,000 0,02657585 0,05324021 ! female pregnancy GO:0007565 164 94 1,000 0,02662183 0,05328796 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,02714765 0,05429531 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,02714765 0,05425021 ! leukocyte differentiation GO:0002521 202 96 1,000 0,02767767 0,05526347 ! positive regulation of immune response GO:0050778 156 96 1,000 0,02767767 0,05521765 ! detection of stimulus GO:0051606 151 96 1,000 0,02767767 0,0551719 ! regulation of protein localization GO:0032880 176 97 1,000 0,02821186 0,05619018 ! interphase GO:0051325 213 98 1,000 0,02875019 0,05721502 ! respiratory burst GO:0045730 17 11 0,000 0,02919475 0,05805172 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02919475 0,05800378 ! neuron fate specification GO:0048665 17 11 0,000 0,02919475 0,05795592 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02919475 0,05790814 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02919475 0,05786044 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,02919475 0,05781282 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,02919475 0,05776528 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02919475 0,05771781 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02919475 0,05767043 ! response to pain GO:0048265 24 11 0,000 0,02919475 0,05762312 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02919475 0,05757588 ! T cell proliferation GO:0042098 26 11 0,000 0,02919475 0,05752873 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02919475 0,05748165 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02919475 0,05743465 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02919475 0,05738773 ! bone resorption GO:0045453 16 11 0,000 0,02919475 0,05734088 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02919475 0,05729411 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02919475 0,05724742 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02919475 0,0572008 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02919475 0,05715425 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02919475 0,05710779 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02919475 0,0570614 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02919475 0,05701508 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02919475 0,05696884 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02919475 0,05692267 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02919475 0,05687658 ! lipid digestion GO:0044241 18 11 0,000 0,02919475 0,05683057 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02919475 0,05678462 ! UV protection GO:0009650 19 11 0,000 0,02919475 0,05673875 ! adult heart development GO:0007512 14 11 0,000 0,02919475 0,05669296 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02919475 0,05664724 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02919475 0,05660159 ! temperature homeostasis GO:0001659 17 11 0,000 0,02919475 0,05655602 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02919475 0,05651052 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02919475 0,0564651 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02919475 0,05641974 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02919475 0,05637446 ! regulation of organ growth GO:0046620 13 11 0,000 0,02919475 0,05632925 ! pigment granule localization GO:0051875 20 11 0,000 0,02919475 0,05628412 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02919475 0,05623905 ! vasoconstriction GO:0042310 18 11 0,000 0,02919475 0,05619406 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02919475 0,05614914 ! embryonic axis specification GO:0000578 18 11 0,000 0,02919475 0,0561043 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02919475 0,05605952 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02919475 0,05601482 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02919475 0,05597018 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02919475 0,05592562 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02919475 0,05588113 GO:0006305|DNA alkylation, ! zymogen activation GO:0031638 15 11 0,000 0,02919475 0,05583671 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02919475 0,05579236 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02919475 0,05574808 ! nucleosome positioning GO:0016584 15 11 0,000 0,02919475 0,05570387 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02919475 0,05565973 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02919475 0,05561566 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02919475 0,05557166 ! acid secretion GO:0046717 18 11 0,000 0,02919475 0,05552773 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02919475 0,05548387 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02919475 0,05544008 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02919475 0,05539636 ! oocyte differentiation GO:0009994 18 11 0,000 0,02919475 0,0553527 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02919475 0,05530912 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02919475 0,0552656 ! cholesterol efflux GO:0033344 19 11 0,000 0,02919475 0,05522215 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02919475 0,05517877 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02919475 0,05513546 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02919475 0,05509222 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02919475 0,05504904 ! embryonic gut development GO:0048566 15 11 0,000 0,02919475 0,05500593 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02919475 0,05496289 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02919475 0,05491992 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02919475 0,05487701 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02919475 0,05483418 ! defense response to fungus GO:0050832 13 11 0,000 0,02919475 0,0547914 ! developmental induction GO:0031128 19 11 0,000 0,02919475 0,0547487 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02919475 0,05470606 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02919475 0,05466349 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02919475 0,05462098 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02919475 0,05457854 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02919475 0,05453616 ! nucleus localization GO:0051647 19 11 0,000 0,02919475 0,05449385 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02919475 0,05445161 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0318067 0,05927724 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0318067 0,05923136 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,0318067 0,05918555 ! virus-host interaction GO:0019048 29 12 0,000 0,0318067 0,05913981 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,0318067 0,05909415 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0318067 0,05904855 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,0318067 0,05900302 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0318067 0,05895756 ! protein complex disassembly GO:0043241 27 12 0,000 0,0318067 0,05891218 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0318067 0,05886686 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0318067 0,05882161 ! hippocampus development GO:0021766 26 12 0,000 0,0318067 0,05877644 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0318067 0,05873133 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0318067 0,05868629 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0318067 0,05864132 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0318067 0,05859642 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0318067 0,05855158 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0318067 0,05850682 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0318067 0,05846212 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0318067 0,0584175 ! drug transport GO:0015893 16 12 0,000 0,0318067 0,05837294 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0318067 0,05832844 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0318067 0,05828402 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0318067 0,05823966 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0318067 0,05819538 ! focal adhesion formation GO:0048041 35 12 0,000 0,0318067 0,05815115 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0318067 0,058107 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0318067 0,05806291 ! forebrain cell migration GO:0021885 21 12 0,000 0,0318067 0,05801889 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0318067 0,05797494 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0318067 0,05793105 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0318067 0,05788723 ! entry into host cell GO:0030260 32 12 0,000 0,0318067 0,05784348 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,0318067 0,05779979 ! monoamine transport GO:0015844 18 12 0,000 0,0318067 0,05775617 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0318067 0,05771261 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0318067 0,05766912 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0318067 0,05762569 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0318067 0,05758233 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0318067 0,05753904 ! protein homotetramerization GO:0051289 21 12 0,000 0,0318067 0,05749581 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0318067 0,05745264 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0318067 0,05740954 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0318067 0,05736651 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0318067 0,05732353 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0318067 0,05728063 ! cranial nerve development GO:0021545 20 12 0,000 0,0318067 0,05723779 ! fucose catabolic process GO:0019317 22 12 0,000 0,0318067 0,05719501 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0318067 0,05715229 ! histone acetylation GO:0016573 26 12 0,000 0,0318067 0,05710964 ! histone methylation GO:0016571 26 12 0,000 0,0318067 0,05706705 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0318067 0,05702453 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0318067 0,05698207 ! gland morphogenesis GO:0022612 29 12 0,000 0,0318067 0,05693967 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,0318067 0,05689734 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0318067 0,05685507 ! T cell homeostasis GO:0043029 25 12 0,000 0,0318067 0,05681286 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0318067 0,05677071 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0318067 0,05672863 ! spleen development GO:0048536 22 12 0,000 0,0318067 0,05668661 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0318067 0,05664465 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0318067 0,05660275 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0318067 0,05656092 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0318067 0,05651914 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0318067 0,05647743 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,0318067 0,05643578 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0318067 0,05639419 ! response to cold GO:0009409 17 12 0,000 0,0318067 0,05635266 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0318067 0,0563112 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0318067 0,05626979 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0344117 0,06083362 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,0344117 0,06078896 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0344117 0,06074436 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,0344117 0,06069982 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,0344117 0,06065535 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,0344117 0,06061095 ! lipid localization GO:0010876 28 13 0,000 0,0344117 0,06056661 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,0344117 0,06052234 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,0344117 0,06047813 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,0344117 0,06043399 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,0344117 0,0603899 ! endocrine pancreas development GO:0031018 22 13 0,000 0,0344117 0,06034589 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,0344117 0,06030194 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,0344117 0,06025805 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,0344117 0,06021423 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0344117 0,06017046 ! methionine metabolic process GO:0006555 27 13 0,000 0,0344117 0,06012677 ! plasma membrane organization GO:0007009 24 13 0,000 0,0344117 0,06008313 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,0344117 0,06003956 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,0344117 0,05999606 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,0344117 0,05995261 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,0344117 0,05990923 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,0344117 0,05986591 ! response to X-ray GO:0010165 25 13 0,000 0,0344117 0,05982266 ! cytokine metabolic process GO:0042107 22 13 0,000 0,0344117 0,05977947 ! exocrine system development GO:0035272 32 13 0,000 0,0344117 0,05973633 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,0344117 0,05969327 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,0344117 0,05965026 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,0344117 0,05960731 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,0344117 0,05956443 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,0344117 0,05952161 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,0344117 0,05947885 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,0344117 0,05943615 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,0344117 0,05939351 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,0344117 0,05935094 ! regulation of cellular pH GO:0030641 22 13 0,000 0,0344117 0,05930842 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0344117 0,05926597 ! ribosome assembly GO:0042255 17 13 0,000 0,0344117 0,05922358 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,0344117 0,05918124 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,0344117 0,05913897 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,0344117 0,05909676 ! chromatin silencing GO:0006342 26 13 0,000 0,0344117 0,05905461 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,0344117 0,05901252 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,0344117 0,05897048 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,0344117 0,05892851 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,0344117 0,0588866 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0344117 0,05884475 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,0344117 0,05880295 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,0344117 0,05876122 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,0344117 0,05871955 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,0344117 0,05867793 ! embryonic placenta development GO:0001892 23 13 0,000 0,0344117 0,05863637 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,0344117 0,05859488 ! insulin secretion GO:0030073 23 13 0,000 0,0344117 0,05855344 ! actin filament polymerization GO:0030041 24 13 0,000 0,0344117 0,05851206 ! acrosome reaction GO:0007340 18 13 0,000 0,0344117 0,05847073 ! rRNA transcription GO:0009303 25 14 0,000 0,03700979 0,06284089 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,03700979 0,06279658 ! reproductive cellular process GO:0048610 20 14 0,000 0,03700979 0,06275232 ! tRNA modification GO:0006400 20 14 0,000 0,03700979 0,06270813 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03700979 0,062664 ! regulation of S phase GO:0033261 23 14 0,000 0,03700979 0,06261993 ! water transport GO:0006833 21 14 0,000 0,03700979 0,06257593 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03700979 0,06253198 ! non-recombinational repair GO:0000726 25 14 0,000 0,03700979 0,0624881 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03700979 0,06244428 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03700979 0,06240052 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03700979 0,06235682 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03700979 0,06231319 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03700979 0,06226961 ! palate development GO:0060021 31 14 0,000 0,03700979 0,0622261 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03700979 0,06218264 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03700979 0,06213925 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03700979 0,06209592 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03700979 0,06205264 ! arginine metabolic process GO:0006525 17 14 0,000 0,03700979 0,06200943 ! regulation of heart rate GO:0002027 24 14 0,000 0,03700979 0,06196628 ! organic alcohol transport GO:0015850 29 14 0,000 0,03700979 0,06192319 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03700979 0,06188016 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03700979 0,06183718 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03700979 0,06179427 GO:0060675|ureteric bud morphogenesis, ! neutral amino acid transport GO:0015804 26 14 0,000 0,03700979 0,06175142 ! L-amino acid transport GO:0015807 30 14 0,000 0,03700979 0,06170862 ! bone mineralization GO:0030282 17 14 0,000 0,03700979 0,06166589 ! stem cell development GO:0048864 43 14 0,000 0,03700979 0,06162321 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03700979 0,0615806 ! cerebellum development GO:0021549 21 14 0,000 0,03700979 0,06153804 ! response to gamma radiation GO:0010332 28 14 0,000 0,03700979 0,06149554 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03700979 0,0614531 ! cofactor transport GO:0051181 26 14 0,000 0,03700979 0,06141072 ! NADP metabolic process GO:0006739 24 14 0,000 0,03700979 0,0613684 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03700979 0,06132613 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03700979 0,06128393 ! intestinal absorption GO:0050892 25 14 0,000 0,03700979 0,06124178 ! oxygen transport GO:0015671 21 14 0,000 0,03700979 0,06119969 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03700979 0,06115765 ! male genitalia development GO:0030539 24 14 0,000 0,03700979 0,06111568 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03700979 0,06107376 ! regulation of axon extension GO:0030516 37 14 0,000 0,03700979 0,0610319 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,03700979 0,0609901 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03700979 0,06094835 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03960096 0,06517094 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03960096 0,0651264 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03960096 0,06508191 ! superoxide anion generation GO:0042554 20 15 0,000 0,03960096 0,06503749 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03960096 0,06499312 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03960096 0,06494882 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03960096 0,06490458 ! copper ion transport GO:0006825 20 15 0,000 0,03960096 0,06486039 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03960096 0,06481627 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03960096 0,06477221 ! sulfate transport GO:0008272 23 15 0,000 0,03960096 0,0647282 ! response to cAMP GO:0051591 22 15 0,000 0,03960096 0,06468426 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03960096 0,06464038 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03960096 0,06459655 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03960096 0,06455279 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03960096 0,06450908 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03960096 0,06446544 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03960096 0,06442185 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03960096 0,06437832 ! pituitary gland development GO:0021983 29 15 0,000 0,03960096 0,06433485 ! vesicle coating GO:0006901 33 15 0,000 0,03960096 0,06429144 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03960096 0,06424809 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03960096 0,0642048 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03960096 0,06416156 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03960096 0,06411838 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03960096 0,06407526 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03960096 0,0640322 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03960096 0,0639892 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03960096 0,06394625 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03960096 0,06390336 ! histone deacetylation GO:0016575 20 15 0,000 0,03960096 0,06386053 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03960096 0,06381776 ! tissue regeneration GO:0042246 26 15 0,000 0,03960096 0,06377504 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03960096 0,06373239 ! water homeostasis GO:0030104 27 15 0,000 0,03960096 0,06368978 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03960096 0,06364724 ! muscle maintenance GO:0046716 26 15 0,000 0,03960096 0,06360475 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03960096 0,06356232 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03960096 0,06351994 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03960096 0,06347763 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03960096 0,06343536 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03960096 0,06339316 ! detection of bacterium GO:0016045 18 15 0,000 0,03960096 0,06335101 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,03960096 0,06330891 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03960096 0,06326688 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03960096 0,06322489 ! peptide hormone processing GO:0016486 23 15 0,000 0,03960096 0,06318297 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04218525 0,06726158 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,04218525 0,06721703 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04218525 0,06717255 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04218525 0,06712812 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04218525 0,06708375 ! bone remodeling GO:0046849 27 16 0,000 0,04218525 0,06703945 ! filopodium assembly GO:0046847 32 16 0,000 0,04218525 0,06699519 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04218525 0,066951 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04218525 0,06690687 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04218525 0,06686279 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04218525 0,06681878 ! startle response GO:0001964 28 16 0,000 0,04218525 0,06677482 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04218525 0,06673091 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04218525 0,06668707 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04218525 0,06664328 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04218525 0,06659955 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04218525 0,06655588 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04218525 0,06651227 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04218525 0,06646871 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04218525 0,06642521 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04218525 0,06638177 ! response to osmotic stress GO:0006970 25 16 0,000 0,04218525 0,06633838 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04218525 0,06629505 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04218525 0,06625178 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04218525 0,06620856 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04218525 0,0661654 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04218525 0,06612229 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04218525 0,06607924 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04218525 0,06603625 ! axon cargo transport GO:0008088 43 16 0,000 0,04218525 0,06599332 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04218525 0,06595044 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04218525 0,06590761 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04218525 0,06586484 ! neuron recognition GO:0008038 35 16 0,000 0,04218525 0,06582213 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04218525 0,06577947 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04218525 0,06573687 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04218525 0,06569432 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04218525 0,06565182 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04218525 0,06560939 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04218525 0,065567 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04218525 0,06552467 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04218525 0,0654824 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04218525 0,06544018 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04218525 0,06539802 ! defense response to virus GO:0051607 37 16 0,000 0,04218525 0,0653559 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04476268 0,06930437 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04476268 0,06925981 ! metencephalon development GO:0022037 30 17 0,000 0,04476268 0,06921529 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04476268 0,06917084 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04476268 0,06912644 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04476268 0,0690821 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04476268 0,06903782 ! signal complex assembly GO:0007172 41 17 0,000 0,04476268 0,06899359 ! endothelial cell migration GO:0043542 28 17 0,000 0,04476268 0,06894942 ! inositol metabolic process GO:0006020 28 17 0,000 0,04476268 0,06890531 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04476268 0,06886125 ! glial cell development GO:0021782 27 17 0,000 0,04476268 0,06881725 ! limbic system development GO:0021761 36 17 0,000 0,04476268 0,06877331 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04476268 0,06872942 ! adult walking behavior GO:0007628 33 17 0,000 0,04476268 0,06868559 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04476268 0,06864181 ! heart looping GO:0001947 30 17 0,000 0,04476268 0,06859809 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04476268 0,06855442 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04476268 0,06851081 ! myoblast differentiation GO:0045445 45 17 0,000 0,04476268 0,06846726 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04476268 0,06842376 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,04476268 0,06838032 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04476268 0,06833693 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04476268 0,06829359 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04476268 0,06825032 ! glycine metabolic process GO:0006544 28 17 0,000 0,04476268 0,06820709 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,04476268 0,06816392 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04476268 0,06812081 ! NAD metabolic process GO:0019674 29 17 0,000 0,04476268 0,06807775 ! membrane budding GO:0006900 37 17 0,000 0,04476268 0,06803474 ! DNA integration GO:0015074 29 17 0,000 0,04476268 0,06799179 ! regulation of protein binding GO:0043393 33 17 0,000 0,04476268 0,0679489 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04476268 0,06790605 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04476268 0,06786326 ! genitalia development GO:0048806 30 17 0,000 0,04476268 0,06782053 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04476268 0,06777785 ! neural crest cell migration GO:0001755 37 17 0,000 0,04476268 0,06773522 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04476268 0,06769265 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04476268 0,06765012 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04476268 0,06760766 ! steroid catabolic process GO:0006706 31 17 0,000 0,04476268 0,06756524 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04476268 0,06752288 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04476268 0,06748058 ! gas transport GO:0015669 25 17 0,000 0,04476268 0,06743832 ! organic cation transport GO:0015695 31 17 0,000 0,04476268 0,06739612 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04476268 0,06735397 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,04476268 0,06731187 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04476268 0,06726983 ! microspike assembly GO:0030035 36 17 0,000 0,04476268 0,06722784 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04476268 0,0671859 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04733325 0,07099987 ! neuron maturation GO:0042551 42 18 0,000 0,04733325 0,07095564 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04733325 0,07091145 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04733325 0,07086733 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,04733325 0,07082326 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04733325 0,07077924 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,04733325 0,07073528 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04733325 0,07069137 ! memory GO:0007613 31 18 0,000 0,04733325 0,07064752 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04733325 0,07060372 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04733325 0,07055997 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04733325 0,07051628 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04733325 0,07047265 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,04733325 0,07042906 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04733325 0,07038553 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04733325 0,07034206 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04733325 0,07029864 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,04733325 0,07025527 ! response to fungus GO:0009620 21 18 0,000 0,04733325 0,07021196 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04733325 0,0701687 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04733325 0,07012549 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04733325 0,07008234 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04733325 0,07003923 ! vitamin transport GO:0051180 27 18 0,000 0,04733325 0,06999619 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04733325 0,06995319 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04733325 0,06991025 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04733325 0,06986736 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,04733325 0,06982452 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04733325 0,06978174 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04733325 0,06973901 ! protein secretion GO:0009306 39 19 0,000 0,04989699 0,07347133 ! positive regulation of translation GO:0045727 30 19 0,000 0,04989699 0,07342639 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04989699 0,07338151 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04989699 0,07333669 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04989699 0,07329191 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04989699 0,0732472 ! lipid phosphorylation GO:0046834 35 19 0,000 0,04989699 0,07320253 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04989699 0,07315792 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04989699 0,07311337 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04989699 0,07306887 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04989699 0,07302442 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04989699 0,07298003 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04989699 0,07293569 ! cerebral cortex development GO:0021987 36 19 0,000 0,04989699 0,07289141 ! pigmentation during development GO:0048066 41 19 0,000 0,04989699 0,07284718 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04989699 0,072803 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,04989699 0,07275888 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04989699 0,07271481 ! neuromuscular junction development GO:0007528 34 19 0,000 0,04989699 0,0726708 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04989699 0,07262683 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04989699 0,07258292 ! peptide cross-linking GO:0018149 37 19 0,000 0,04989699 0,07253907 ! protein export from nucleus GO:0006611 36 19 0,000 0,04989699 0,07249526 ! heart process GO:0003015 30 19 0,000 0,04989699 0,07245151 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04989699 0,07240781 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04989699 0,07236417 ! visual learning GO:0008542 36 19 0,000 0,04989699 0,07232057 ! cellular pigmentation GO:0033059 36 19 0,000 0,04989699 0,07227703 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04989699 0,07223355 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04989699 0,07219011 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04989699 0,07214673 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04989699 0,0721034 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04989699 0,07206012 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04989699 0,07201689 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04989699 0,07197371 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04989699 0,07193059 ! cilium assembly GO:0042384 37 19 0,000 0,04989699 0,07188752 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04989699 0,0718445 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05245391 0,07548093 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,05245391 0,07543581 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05245391 0,07539075 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05245391 0,07534574 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05245391 0,07530079 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,05245391 0,07525588 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,05245391 0,07521103 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05245391 0,07516624 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,05245391 0,0751215 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05245391 0,07507681 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05245391 0,07503217 ! response to alkaloid GO:0043279 38 20 0,000 0,05245391 0,07498759 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05245391 0,07494306 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,05245391 0,07489859 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,05245391 0,07485416 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05245391 0,07480979 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05245391 0,07476547 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05245391 0,07472121 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,05245391 0,07467699 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05245391 0,07463283 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05245391 0,07458872 ! body fluid secretion GO:0007589 31 20 0,000 0,05245391 0,07454466 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05245391 0,07450066 ! peptide secretion GO:0002790 35 20 0,000 0,05245391 0,07445671 ! stem cell differentiation GO:0048863 53 20 0,000 0,05245391 0,0744128 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05245391 0,07436895 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05245391 0,07432516 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05245391 0,07428141 ! sensory perception of pain GO:0019233 30 20 0,000 0,05245391 0,07423772 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05245391 0,07419407 ! diencephalon development GO:0021536 34 20 0,000 0,05245391 0,07415048 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05245391 0,07410694 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05245391 0,07406345 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05245391 0,07402001 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,05245391 0,07397662 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05245391 0,07393328 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05245391 0,07389 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05245391 0,07384676 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05245391 0,07380358 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05245391 0,07376044 ! regulation of glucose import GO:0046324 29 20 0,000 0,05245391 0,07371736 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,05245391 0,07367432 ! actin filament-based movement GO:0030048 43 20 0,000 0,05245391 0,07363134 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05245391 0,07358841 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05245391 0,07354552 ! negative regulation of translation GO:0017148 29 20 0,000 0,05245391 0,07350269 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05245391 0,0734599 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,05245391 0,07341717 ! regulation of cell killing GO:0031341 42 21 0,000 0,05500404 0,0769417 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05500404 0,07689699 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05500404 0,07685234 ! hormone secretion GO:0046879 38 21 0,000 0,05500404 0,07680773 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05500404 0,07676318 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05500404 0,07671868 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05500404 0,07667423 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05500404 0,07662984 ! axis specification GO:0009798 38 21 0,000 0,05500404 0,07658549 ! ovarian follicle development GO:0001541 35 21 0,000 0,05500404 0,0765412 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,05500404 0,07649695 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05500404 0,07645276 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05500404 0,07640862 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05500404 0,07636453 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05500404 0,07632049 ! cell aging GO:0007569 44 21 0,000 0,05500404 0,0762765 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05500404 0,07623256 ! cytolysis GO:0019835 24 21 0,000 0,05500404 0,07618867 ! vasodilation GO:0042311 39 21 0,000 0,05500404 0,07614484 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05500404 0,07610105 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05500404 0,07605731 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05500404 0,07601363 ! oogenesis GO:0048477 36 21 0,000 0,05500404 0,07596999 ! DNA modification GO:0006304 34 21 0,000 0,05500404 0,07592641 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,05500404 0,07588287 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,05500404 0,07583938 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05500404 0,07579595 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05500404 0,07575256 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,05500404 0,07570923 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05500404 0,07566594 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05500404 0,0756227 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05500404 0,07557951 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05500404 0,07553637 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05500404 0,07549328 ! collagen catabolic process GO:0030574 28 21 0,000 0,05500404 0,07545024 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05500404 0,07540725 ! gut development GO:0048565 39 21 0,000 0,05500404 0,07536431 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,05754739 0,07880423 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05754739 0,0787594 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05754739 0,07871463 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05754739 0,0786699 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05754739 0,07862523 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,05754739 0,07858061 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,05754739 0,07853603 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05754739 0,07849151 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,05754739 0,07844704 ! regeneration GO:0031099 41 22 0,000 0,05754739 0,07840262 ! keratinization GO:0031424 28 22 0,000 0,05754739 0,07835825 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,05754739 0,07831393 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05754739 0,07826966 ! sensory perception of taste GO:0050909 28 22 0,000 0,05754739 0,07822544 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,05754739 0,07818127 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,05754739 0,07813715 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05754739 0,07809308 ! vacuolar transport GO:0007034 36 22 0,000 0,05754739 0,07804906 ! lysosome organization GO:0007040 41 22 0,000 0,05754739 0,07800509 ! central nervous system neuron development GO:0021954 46 22 0,000 0,05754739 0,07796116 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,05754739 0,07791729 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05754739 0,07787347 ! fucose metabolic process GO:0006004 39 22 0,000 0,05754739 0,0778297 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,05754739 0,07778597 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,05754739 0,0777423 ! ureteric bud development GO:0001657 43 22 0,000 0,05754739 0,07769867 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,05754739 0,07765509 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,05754739 0,07761156 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05754739 0,07756808 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,05754739 0,07752465 ! sarcomere organization GO:0045214 30 22 0,000 0,05754739 0,07748127 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,05754739 0,07743793 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05754739 0,07739465 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,05754739 0,07735141 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,05754739 0,07730822 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,05754739 0,07726508 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,06008398 0,0806258 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06008398 0,08058086 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,06008398 0,08053597 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06008398 0,08049113 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06008398 0,08044633 ! gluconeogenesis GO:0006094 33 23 0,000 0,06008398 0,08040159 ! viral genome replication GO:0019079 41 23 0,000 0,06008398 0,0803569 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06008398 0,08031226 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06008398 0,08026766 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06008398 0,08022312 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06008398 0,08017863 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06008398 0,08013418 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06008398 0,08008979 ! visual behavior GO:0007632 42 23 0,000 0,06008398 0,08004544 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06008398 0,08000114 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,06008398 0,07995689 ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,06008398 0,07991269 ! peroxisome organization GO:0007031 37 23 0,000 0,06008398 0,07986854 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06008398 0,07982444 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06008398 0,07978039 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06008398 0,07973638 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,06008398 0,07969243 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,06008398 0,07964852 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06008398 0,07960466 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06008398 0,07956085 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06008398 0,07951709 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06008398 0,07947337 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06008398 0,0794297 ! fatty acid transport GO:0015908 44 23 0,000 0,06008398 0,07938609 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06008398 0,07934251 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06008398 0,07929899 ! hormone transport GO:0009914 40 23 0,000 0,06008398 0,07925552 ! cell-cell recognition GO:0009988 25 23 0,000 0,06008398 0,07921209 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06008398 0,07916871 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06008398 0,07912538 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,06261383 0,08241186 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,06261383 0,0823668 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,06261383 0,08232179 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,06261383 0,08227683 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06261383 0,08223192 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,06261383 0,08218706 ! vesicle docking GO:0048278 47 24 0,000 0,06261383 0,08214224 ! spinal cord development GO:0021510 47 24 0,000 0,06261383 0,08209748 ! vacuole organization GO:0007033 43 24 0,000 0,06261383 0,08205276 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06261383 0,0820081 ! digestive system process GO:0022600 39 24 0,000 0,06261383 0,08196348 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06261383 0,08191891 ! regulation of behavior GO:0050795 43 24 0,000 0,06261383 0,08187439 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06261383 0,08182991 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,06261383 0,08178549 ! membrane depolarization GO:0051899 39 24 0,000 0,06261383 0,08174111 ! pallium development GO:0021543 49 24 0,000 0,06261383 0,08169679 ! pentose metabolic process GO:0019321 35 24 0,000 0,06261383 0,08165251 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,06261383 0,08160827 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06261383 0,08156409 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06261383 0,08151995 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06261383 0,08147586 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,06261383 0,08143182 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06261383 0,08138783 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06261383 0,08134388 ! regulation of amine transport GO:0051952 40 24 0,000 0,06261383 0,08129999 ! protein tetramerization GO:0051262 52 24 0,000 0,06261383 0,08125613 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,06513695 0,08448491 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,06513695 0,08443939 ! myelination GO:0042552 45 25 0,000 0,06513695 0,08439392 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06513695 0,08434849 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,06513695 0,08430312 ! phototransduction GO:0007602 33 25 0,000 0,06513695 0,0842578 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,06513695 0,08421252 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,06513695 0,08416729 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,06513695 0,08412212 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06513695 0,08407699 ! chromosome condensation GO:0030261 45 25 0,000 0,06513695 0,0840319 ! osteoblast differentiation GO:0001649 60 25 0,000 0,06513695 0,08398687 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,06513695 0,08394189 ! neural crest cell development GO:0014032 54 25 0,000 0,06513695 0,08389695 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,06513695 0,08385206 ! negative regulation of cell development GO:0010721 73 25 0,000 0,06513695 0,08380722 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,06513695 0,08376243 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06513695 0,08371768 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06513695 0,08367299 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,06513695 0,08362834 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,06513695 0,08358373 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,06513695 0,08353918 ! immunoglobulin production GO:0002377 55 25 0,000 0,06513695 0,08349467 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06513695 0,08345021 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06513695 0,0834058 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06513695 0,08336144 ! neural tube closure GO:0001843 49 25 0,000 0,06513695 0,08331712 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,06513695 0,08327285 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,06765336 0,08644397 ! embryonic pattern specification GO:0009880 44 26 0,000 0,06765336 0,08639808 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,06765336 0,08635225 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,06765336 0,08630646 ! initiation of viral infection GO:0019059 57 26 0,000 0,06765336 0,08626073 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,06765336 0,08621504 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,06765336 0,0861694 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,06765336 0,08612381 ! tube lumen formation GO:0035148 50 26 0,000 0,06765336 0,08607826 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,06765336 0,08603277 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,06765336 0,08598732 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,06765336 0,08594192 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,06765336 0,08589657 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,06765336 0,08585126 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,06765336 0,08580601 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,06765336 0,0857608 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,06765336 0,08571564 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,06765336 0,08567052 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,06765336 0,08562546 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,06765336 0,08558044 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,06765336 0,08553547 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,06765336 0,08549054 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,06765336 0,08544567 ! blastocyst development GO:0001824 49 26 0,000 0,06765336 0,08540084 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,06765336 0,08535605 ! neuron fate commitment GO:0048663 48 27 0,000 0,07016309 0,08847609 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,07016309 0,08842975 ! iron ion transport GO:0006826 59 27 0,000 0,07016309 0,08838345 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,07016309 0,0883372 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,07016309 0,088291 ! protein amino acid acylation GO:0043543 55 27 0,000 0,07016309 0,08824484 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,07016309 0,08819874 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,07016309 0,08815268 ! fat cell differentiation GO:0045444 50 27 0,000 0,07016309 0,08810667 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,07016309 0,08806071 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,07016309 0,0880148 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,07016309 0,08796893 ! autophagy GO:0006914 41 27 0,000 0,07016309 0,08792312 ! male gonad development GO:0008584 44 27 0,000 0,07016309 0,08787735 ! response to toxin GO:0009636 47 27 0,000 0,07016309 0,08783163 ! primary neural tube formation GO:0014020 51 27 0,000 0,07016309 0,08778595 ! base-excision repair GO:0006284 41 27 0,000 0,07016309 0,08774033 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,07016309 0,08769475 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,07016309 0,08764921 ! glutathione metabolic process GO:0006749 39 27 0,000 0,07016309 0,08760373 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,07016309 0,08755829 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,07016309 0,0875129 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,07016309 0,08746756 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,07266614 0,09054103 ! circadian rhythm GO:0007623 50 28 0,000 0,07266614 0,09049416 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,07266614 0,09044735 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,07266614 0,09040058 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,07266614 0,09035386 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,07266614 0,09030719 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,07266614 0,09026057 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,07266614 0,090214 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,07266614 0,09016747 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,07266614 0,09012099 ! synaptogenesis GO:0007416 42 28 0,000 0,07266614 0,09007456 ! lipid oxidation GO:0034440 43 28 0,000 0,07266614 0,09002818 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,07266614 0,08998185 ! translational initiation GO:0006413 65 29 0,000 0,07516253 0,09302523 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,07516253 0,0929774 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,07516253 0,09292963 ! regulation of pH GO:0006885 43 29 0,000 0,07516253 0,0928819 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,07516253 0,09283422 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,07516253 0,09278658 ! catechol metabolic process GO:0009712 54 29 0,000 0,07516253 0,092739 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,07516253 0,09269147 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,07516253 0,09264398 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,07516253 0,09259655 ! cell fate determination GO:0001709 60 29 0,000 0,07516253 0,09254916 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,07516253 0,09250182 ! detection of light stimulus GO:0009583 38 29 0,000 0,07516253 0,09245453 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,07516253 0,09240728 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,07516253 0,09236009 ! tissue homeostasis GO:0001894 48 29 0,000 0,07516253 0,09231294 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,07516253 0,09226584 ! phenol metabolic process GO:0018958 55 30 0,000 0,07765229 0,09527354 ! zinc ion transport GO:0006829 45 30 0,000 0,07765229 0,09522498 ! membrane docking GO:0022406 61 30 0,000 0,07765229 0,09517647 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,07765229 0,09512801 ! cell junction assembly GO:0034329 78 30 0,000 0,07765229 0,0950796 ! regulation of innate immune response GO:0045088 51 30 0,000 0,07765229 0,09503124 ! myofibril assembly GO:0030239 47 30 0,000 0,07765229 0,09498292 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,07765229 0,09493466 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,07765229 0,09488644 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,07765229 0,09483828 ! phospholipid transport GO:0015914 51 30 0,000 0,07765229 0,09479016 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,07765229 0,09474209 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,07765229 0,09469408 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,07765229 0,0946461 ! eye morphogenesis GO:0048592 60 30 0,000 0,07765229 0,09459818 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,08013543 0,09757381 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,08013543 0,09752445 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,08013543 0,09747515 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,08013543 0,09742589 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,08013543 0,09737669 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,08013543 0,09732753 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,08013543 0,09727843 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,08013543 0,09722937 ! ovulation cycle process GO:0022602 49 31 0,000 0,08013543 0,09718036 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,08013543 0,09713141 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,08013543 0,0970825 ! peptide transport GO:0015833 55 31 0,000 0,08013543 0,09703364 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,08013543 0,09698483 ! iron ion homeostasis GO:0055072 54 31 0,000 0,08013543 0,09693607 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,08013543 0,09688736 ! mesoderm formation GO:0001707 69 31 0,000 0,08013543 0,09683869 ! natural killer cell activation GO:0030101 45 31 0,000 0,08013543 0,09679008 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,08013543 0,09674152 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,08013543 0,096693 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,08013543 0,09664453 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,08013543 0,09659611 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,08261196 0,09953149 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,08261196 0,09948167 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,08261196 0,09943191 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,08261196 0,09938219 ! cholesterol transport GO:0030301 56 32 0,000 0,08261196 0,09933252 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,08261196 0,09928291 ! spliceosome assembly GO:0000245 67 32 0,000 0,08261196 0,09923334 ! spindle organization GO:0007051 46 32 0,000 0,08261196 0,09918382 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,08261196 0,09913436 ! metanephros development GO:0001656 74 32 0,000 0,08261196 0,09908494 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,08261196 0,09903557 ! response to ionizing radiation GO:0010212 65 32 0,000 0,08261196 0,09898625 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,08261196 0,09893697 ! muscle cell development GO:0055001 49 32 0,000 0,08261196 0,09888775 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,08261196 0,09883858 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,08261196 0,09878945 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,08261196 0,09874038 ! ovulation cycle GO:0042698 51 32 0,000 0,08261196 0,09869135 ! peripheral nervous system development GO:0007422 64 32 0,000 0,08261196 0,09864237 ! BMP signaling pathway GO:0030509 64 32 0,000 0,08261196 0,09859344 ! hindbrain development GO:0030902 61 32 0,000 0,08261196 0,09854456 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,08261196 0,09849573 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,08261196 0,09844695 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,08508191 0,10134014 ! post-embryonic development GO:0009791 69 33 0,000 0,08508191 0,10129 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,08508191 0,1012399 ! protein targeting to membrane GO:0006612 68 33 0,000 0,08508191 0,10118986 ! ceramide metabolic process GO:0006672 64 33 0,000 0,08508191 0,10113986 ! formation of primary germ layer GO:0001704 72 33 0,000 0,08508191 0,10108992 ! cell fate specification GO:0001708 52 33 0,000 0,08508191 0,10104002 ! sterol transport GO:0015918 57 33 0,000 0,08508191 0,10099017 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,08508191 0,10094038 ! adult locomotory behavior GO:0008344 59 33 0,000 0,08508191 0,10089063 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,08754529 0,10376058 ! glial cell differentiation GO:0010001 63 34 0,000 0,08754529 0,10370949 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,08754529 0,10365845 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,08754529 0,10360747 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,08754529 0,10355653 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,08754529 0,10350564 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,08754529 0,1034548 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,08754529 0,10340401 ! mismatch repair GO:0006298 46 34 0,000 0,08754529 0,10335328 ! spermatid development GO:0007286 63 34 0,000 0,08754529 0,10330259 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,08754529 0,10325195 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,08754529 0,10320136 ! placenta development GO:0001890 53 34 0,000 0,08754529 0,10315082 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,09000212 0,10599369 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,09000212 0,10594183 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,09000212 0,10589003 ! odontogenesis GO:0042476 66 35 0,000 0,09000212 0,10583828 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,09000212 0,10578657 ! female gonad development GO:0008585 58 35 0,000 0,09000212 0,10573492 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,09000212 0,10568331 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,09000212 0,10563176 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,09000212 0,10558026 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,09000212 0,10552881 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,09000212 0,1054774 ! neural tube formation GO:0001841 67 35 0,000 0,09000212 0,10542605 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,09245242 0,10824356 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,09245242 0,10819092 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,09245242 0,10813832 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,09245242 0,10808577 ! cell junction organization GO:0034330 86 36 0,000 0,09245242 0,10803328 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,09245242 0,10798084 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,09245242 0,10792844 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,09245242 0,1078761 ! aerobic respiration GO:0009060 55 36 0,000 0,09245242 0,10782381 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,09245242 0,10777157 ! embryonic organ development GO:0048568 57 36 0,000 0,09245242 0,10771938 ! RNA export from nucleus GO:0006405 56 37 0,000 0,0948962 0,11051319 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,0948962 0,11045973 ! meiosis I GO:0007127 65 37 0,000 0,0948962 0,11040632 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,0948962 0,11035295 ! sister chromatid segregation GO:0000819 58 37 0,000 0,0948962 0,11029964 ! actomyosin structure organization GO:0031032 62 37 0,000 0,0948962 0,11024638 ! tissue remodeling GO:0048771 76 37 0,000 0,0948962 0,11019318 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,0948962 0,11014002 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,0948962 0,11008691 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,0948962 0,11003386 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,0948962 0,10998086 ! pigment metabolic process GO:0042440 80 37 0,000 0,0948962 0,10992791 ! spermatid differentiation GO:0048515 66 37 0,000 0,0948962 0,109875 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,0948962 0,10982215 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,09733348 0,11258863 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,09733348 0,11253453 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,09733348 0,11248048 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,09733348 0,11242648 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,09733348 0,11237253 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,09733348 0,11231864 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,09733348 0,11226479 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,09733348 0,112211 ! lipid homeostasis GO:0055088 67 38 0,000 0,09733348 0,11215726 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,09733348 0,11210357 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,09733348 0,11204993 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,09733348 0,11199635 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,09733348 0,11194281 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 0,000 0,09733348 0,11188933 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,09976428 0,11462887 ! learning GO:0007612 77 39 0,000 0,09976428 0,11457416 ! ear morphogenesis GO:0042471 60 39 0,000 0,09976428 0,11451949 ! organic ether metabolic process GO:0018904 55 39 0,000 0,09976428 0,11446488 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,09976428 0,11441032 ! segmentation GO:0035282 67 39 0,000 0,09976428 0,11435582 ! ion transmembrane transport GO:0034220 66 39 0,000 0,09976428 0,11430136 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,09976428 0,11424696 ! RNA modification GO:0009451 57 39 0,000 0,09976428 0,11419261 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,09976428 0,11413831 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,10218861 0,11685637 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,10218861 0,11680086 ! feeding behavior GO:0007631 59 40 0,000 0,10218861 0,1167454 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,10218861 0,11668999 ! mesenchymal cell development GO:0014031 87 40 0,000 0,10218861 0,11663463 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,10218861 0,11657933 ! cytokinesis GO:0000910 72 40 0,000 0,10218861 0,11652408 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,1046065 0,11922465 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,1046065 0,1191682 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,1046065 0,1191118 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,1046065 0,11905546 ! gliogenesis GO:0042063 88 41 0,000 0,1046065 0,11899917 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,1046065 0,11894293 ! T cell differentiation GO:0030217 81 41 0,000 0,1046065 0,11888674 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,1046065 0,11883061 ! female gamete generation GO:0007292 61 41 0,000 0,1046065 0,11877453 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,1046065 0,11871851 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,10701795 0,12139802 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,10701795 0,12134081 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,10701795 0,12128365 ! regulation of tube size GO:0035150 71 42 0,000 0,10701795 0,12122655 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,10701795 0,1211695 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,10701795 0,12111251 ! neuron migration GO:0001764 79 42 0,000 0,10701795 0,12105557 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,10701795 0,12099868 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,10942299 0,1236598 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,10942299 0,12360174 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,10942299 0,12354374 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,10942299 0,1234858 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,10942299 0,1234279 ! glucose transport GO:0015758 65 43 0,000 0,10942299 0,12337006 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,10942299 0,12331228 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,10942299 0,12325455 ! neural tube development GO:0021915 77 43 0,000 0,10942299 0,12319687 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,10942299 0,12313925 ! striated muscle contraction GO:0006941 77 43 0,000 0,10942299 0,12308168 ! phagocytosis GO:0006909 90 43 0,000 0,10942299 0,12302417 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,10942299 0,12296671 ! hexose transport GO:0008645 67 44 0,000 0,11182163 0,12560357 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,11182163 0,12554496 ! male sex differentiation GO:0046661 76 44 0,000 0,11182163 0,1254864 ! double-strand break repair GO:0006302 81 44 0,000 0,11182163 0,1254279 ! biopolymer methylation GO:0043414 84 44 0,000 0,11182163 0,12536945 ! developmental growth GO:0048589 82 44 0,000 0,11182163 0,12531106 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,11421389 0,12793232 ! glycolysis GO:0006096 65 45 0,000 0,11421389 0,12787279 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,11421389 0,12781331 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,11421389 0,12775389 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,11421389 0,12769453 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,11421389 0,12763522 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,11421389 0,12757596 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,11421389 0,12751676 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,11421389 0,12745762 ! cell growth GO:0016049 84 45 0,000 0,11421389 0,12739853 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,11659979 0,12999958 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,11659979 0,12993937 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,11659979 0,12987921 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,11659979 0,12981911 ! pigmentation GO:0043473 100 46 0,000 0,11659979 0,12975906 ! response to insulin stimulus GO:0032868 95 46 0,000 0,11659979 0,12969907 ! positive regulation of defense response GO:0031349 76 47 0,000 0,11897934 0,13228479 ! endosome transport GO:0016197 108 47 0,000 0,11897934 0,13222369 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,11897934 0,13216264 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,11897934 0,13210166 ! methylation GO:0032259 90 47 0,000 0,11897934 0,13204072 ! protein homooligomerization GO:0051260 76 47 0,000 0,11897934 0,13197985 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,12135256 0,13455035 ! Notch signaling pathway GO:0007219 96 48 0,000 0,12135256 0,13448837 ! cellular component disassembly GO:0022411 86 48 0,000 0,12135256 0,13442645 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,12135256 0,13436459 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,12135256 0,13430278 ! activation of caspase activity GO:0006919 84 48 0,000 0,12135256 0,13424103 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,12135256 0,13417934 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,12371946 0,13673359 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,12371946 0,13667081 ! regulation of ion transport GO:0043269 77 49 0,000 0,12371946 0,13660809 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,12371946 0,13654542 ! peptide metabolic process GO:0006518 76 49 0,000 0,12371946 0,13648282 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,12371946 0,13642027 ! endocrine system development GO:0035270 104 49 0,000 0,12371946 0,13635777 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,12371946 0,13629534 ! neuromuscular process GO:0050905 99 50 0,000 0,12608007 0,13883233 ! regulation of ossification GO:0030278 117 50 0,000 0,12608007 0,13876882 ! inner ear development GO:0048839 79 50 0,000 0,12608007 0,13870537 ! histone modification GO:0016570 91 50 0,000 0,12608007 0,13864198 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,12608007 0,13857864 ! positive regulation of binding GO:0051099 78 51 0,000 0,12843439 0,14110189 ! viral infectious cycle GO:0019058 99 51 0,000 0,12843439 0,14103749 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,12843439 0,14097315 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,12843439 0,14090887 ! excretion GO:0007588 83 51 0,000 0,12843439 0,14084464 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,12843439 0,14078048 ! chromatin remodeling GO:0006338 109 51 0,000 0,12843439 0,14071637 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,12843439 0,14065232 ! vesicle organization GO:0016050 107 51 0,000 0,12843439 0,14058833 ! regulation of cell shape GO:0008360 125 51 0,000 0,12843439 0,1405244 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,12843439 0,14046052 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,13078245 0,14296346 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,13078245 0,14289854 ! membrane fusion GO:0006944 110 52 0,000 0,13078245 0,14283367 ! positive regulation of growth GO:0045927 90 52 0,000 0,13078245 0,14276887 ! covalent chromatin modification GO:0016569 101 52 0,000 0,13078245 0,14270412 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,13078245 0,14263943 ! amino acid activation GO:0043038 92 52 0,000 0,13078245 0,1425748 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,13078245 0,14251023 ! RNA catabolic process GO:0006401 93 53 0,000 0,13312427 0,14499637 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,13312427 0,14493076 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,13312427 0,14486521 ! cell maturation GO:0048469 100 53 0,000 0,13312427 0,14479972 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,13312427 0,14473429 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,13312427 0,14466892 ! response to UV GO:0009411 104 53 0,000 0,13312427 0,14460361 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,13545985 0,14707419 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,13545985 0,14700785 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,13545985 0,14694157 ! cell recognition GO:0008037 85 54 0,000 0,13545985 0,14687535 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,13545985 0,14680919 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,13545985 0,14674309 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,13545985 0,14667705 ! chloride transport GO:0006821 90 55 0,000 0,13778922 0,14913219 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,13778922 0,14906513 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,13778922 0,14899814 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,13778922 0,1489312 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,13778922 0,14886433 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,13778922 0,14879751 ! gastrulation GO:0007369 112 55 0,000 0,13778922 0,14873076 ! heart morphogenesis GO:0003007 97 55 0,000 0,13778922 0,14866406 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,13778922 0,14859742 ! RNA elongation GO:0006354 79 55 0,000 0,13778922 0,14853085 ! nuclear export GO:0051168 97 55 0,000 0,13778922 0,14846433 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,13778922 0,14839788 ! regulation of actin filament length GO:0030832 105 56 0,000 0,14011238 0,15083239 ! sensory perception of smell GO:0007608 80 56 0,000 0,14011238 0,15076494 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,14011238 0,15069754 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,14011238 0,1506302 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,14011238 0,15056293 ! proton transport GO:0015992 94 56 0,000 0,14011238 0,15049571 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,14011238 0,15042856 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,14242937 0,15284793 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,14242937 0,15277979 ! muscle fiber development GO:0048747 112 57 0,000 0,14242937 0,1527117 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,14242937 0,15264368 ! lipid modification GO:0030258 97 57 0,000 0,14242937 0,15257572 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,14242937 0,15250782 ! hydrogen transport GO:0006818 97 58 0,000 0,14474019 0,15491321 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,14474019 0,15484433 ! regulation of endocytosis GO:0030100 91 58 0,000 0,14474019 0,15477551 ! adult behavior GO:0030534 99 58 0,000 0,14474019 0,15470675 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,14474019 0,15463805 ! regulation of cellular component size GO:0032535 109 59 0,000 0,14704486 0,15703059 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,14704486 0,15696093 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,14704486 0,15689132 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,14704486 0,15682178 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,14934339 0,15920257 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,14934339 0,15913207 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,14934339 0,15906162 ! camera-type eye development GO:0043010 116 60 0,000 0,14934339 0,15899124 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,14934339 0,15892092 ! kidney development GO:0001822 122 60 0,000 0,14934339 0,15885066 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,15163581 0,16121775 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,15163581 0,16114654 ! mesoderm development GO:0007498 119 61 0,000 0,15163581 0,16107539 ! tRNA processing GO:0008033 89 61 0,000 0,15163581 0,16100431 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,15163581 0,16093329 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,15163581 0,16086233 ! ear development GO:0043583 103 62 0,000 0,15392213 0,16321579 ! viral reproductive process GO:0022415 126 62 0,000 0,15392213 0,16314389 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,15392213 0,16307205 ! gonad development GO:0008406 98 62 0,000 0,15392213 0,16300028 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,15392213 0,16292857 ! regulation of mitosis GO:0007088 105 63 0,000 0,15620236 0,16526951 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,15620236 0,16519686 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,15620236 0,16512428 ! cell redox homeostasis GO:0045454 102 64 0,000 0,15847652 0,16745476 ! single fertilization GO:0007338 75 64 0,000 0,15847652 0,16738125 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,15847652 0,16730781 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,16074462 0,16962788 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,16074462 0,16955351 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,16074462 0,16947921 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,16074462 0,16940498 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,16300669 0,1717137 ! actin filament organization GO:0007015 148 66 0,000 0,16300669 0,17163855 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,16300669 0,17156347 ! extracellular matrix organization GO:0030198 133 66 0,000 0,16300669 0,17148846 ! secondary metabolic process GO:0019748 116 66 0,000 0,16300669 0,1714135 ! developmental maturation GO:0021700 116 66 0,000 0,16300669 0,17133862 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,16526274 0,17363412 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,16526274 0,17355834 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,16526274 0,17348261 ! lung development GO:0030324 144 67 0,000 0,16526274 0,17340695 ! chromosome segregation GO:0007059 113 67 0,000 0,16526274 0,17333136 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,16526274 0,17325584 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,16526274 0,17318038 ! hexose catabolic process GO:0019320 104 67 0,000 0,16526274 0,17310498 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,16751278 0,17538544 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,16751278 0,17530915 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,16751278 0,17523293 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,16751278 0,17515678 ! regulation of lipase activity GO:0060191 130 68 0,000 0,16751278 0,17508069 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,16751278 0,17500466 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,16751278 0,17492871 ! negative regulation of cell size GO:0045792 134 69 0,000 0,16975683 0,1771952 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,16975683 0,17711836 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,16975683 0,17704158 ! urogenital system development GO:0001655 137 69 0,000 0,16975683 0,17696487 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,16975683 0,17688823 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,16975683 0,17681166 ! antigen processing and presentation GO:0019882 104 69 0,000 0,16975683 0,17673515 ! appendage morphogenesis GO:0035107 135 70 0,000 0,1719949 0,17898778 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,17422702 0,18123226 ! reproductive structure development GO:0048608 113 71 0,000 0,17422702 0,18115394 ! appendage development GO:0048736 136 71 0,000 0,17422702 0,18107569 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,17422702 0,1809975 ! regulation of caspase activity GO:0043281 122 72 0,000 0,17645319 0,18323107 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,17645319 0,18315202 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,17645319 0,18307304 ! carbohydrate transport GO:0008643 110 72 0,000 0,17645319 0,18299413 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,17645319 0,18291529 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,17645319 0,18283651 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,17645319 0,18275781 ! respiratory system development GO:0060541 153 72 0,000 0,17645319 0,18267917 ! learning or memory GO:0007611 147 73 0,000 0,17867344 0,18489819 ! regulation of blood pressure GO:0008217 125 73 0,000 0,17867344 0,1848187 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,17867344 0,18473928 ! fertilization GO:0009566 90 73 0,000 0,17867344 0,18465992 ! transition metal ion transport GO:0000041 126 74 0,000 0,18088777 0,18686818 ! neurotransmitter transport GO:0006836 123 74 0,000 0,18088777 0,18678798 ! meiosis GO:0007126 121 74 0,000 0,18088777 0,18670784 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,18088777 0,18662778 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,18088777 0,18654779 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,18088777 0,18646786 ! eye development GO:0001654 143 74 0,000 0,18088777 0,186388 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,18309621 0,18858283 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,18309621 0,18850213 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,18309621 0,18842151 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,18309621 0,18834095 ! meiotic cell cycle GO:0051321 122 75 0,000 0,18309621 0,18826046 ! rhythmic process GO:0048511 128 75 0,000 0,18309621 0,18818004 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,18529877 0,19036244 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,18529877 0,19028119 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,18529877 0,19020002 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,18749546 0,19237274 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,18749546 0,19229074 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,18749546 0,19220881 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,1896863 0,19437191 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,1896863 0,19428916 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,19187131 0,19644356 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,19187131 0,19636 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,19187131 0,19627652 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,19187131 0,1961931 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,19187131 0,19610976 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,19187131 0,19602648 ! muscle cell differentiation GO:0042692 159 80 0,000 0,19405049 0,19816871 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,19405049 0,19808464 ! protein import into nucleus GO:0006606 158 80 0,000 0,19405049 0,19800063 ! inorganic anion transport GO:0015698 138 80 0,000 0,19405049 0,1979167 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,19622388 0,20004858 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,19622388 0,19996385 ! digestion GO:0007586 112 81 0,000 0,19622388 0,19987919 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,19622388 0,1997946 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,19622388 0,19971009 ! nuclear import GO:0051170 161 81 0,000 0,19622388 0,19962564 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,19839147 0,20174551 ! response to drug GO:0042493 143 82 0,000 0,19839147 0,20166028 ! response to oxygen levels GO:0070482 176 83 0,000 0,20055329 0,20377163 ! negative regulation of growth GO:0045926 155 84 0,000 0,20270936 0,20587535 ! regulation of ligase activity GO:0051340 142 84 0,000 0,20270936 0,20578848 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,20270936 0,20570169 ! nucleosome assembly GO:0006334 122 85 0,000 0,20485967 0,20779611 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,20485967 0,20770855 ! amine biosynthetic process GO:0009309 138 86 0,000 0,20700427 0,20979455 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,20700427 0,20970622 ! chromatin assembly GO:0031497 124 86 0,000 0,20700427 0,20961796 ! tube morphogenesis GO:0035239 176 86 0,000 0,20700427 0,20952977 ! mitochondrion organization GO:0007005 148 86 0,000 0,20700427 0,20944166 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,20914314 0,21151677 ! protein localization in nucleus GO:0034504 176 87 0,000 0,20914314 0,2114279 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,21127632 0,21349468 ! regulation of neurological system process GO:0031644 148 88 0,000 0,21127632 0,21340505 ! cellular defense response GO:0006968 114 89 0,000 0,21340382 0,21546353 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,21340382 0,21537315 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,21552565 0,21742336 ! sex differentiation GO:0007548 145 90 0,000 0,21552565 0,21733224 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,21552565 0,21724119 ! sterol metabolic process GO:0016125 152 91 0,000 0,21764183 0,21928234 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,21764183 0,21919056 ! regulation of defense response GO:0031347 149 92 0,000 0,21975237 0,22122351 ! nucleosome organization GO:0034728 138 92 0,000 0,21975237 0,22113099 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,21975237 0,22103854 ! vitamin metabolic process GO:0006766 139 92 0,000 0,21975237 0,22094617 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,22185728 0,22296935 GO:0010498|proteasomal protein catabolic process, ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,22395659 0,2249852 ! transcription initiation GO:0006352 153 94 0,000 0,22395659 0,2248913 ! forebrain development GO:0030900 188 95 0,000 0,2260503 0,22689905 ! mRNA transport GO:0051028 169 96 0,000 0,22813843 0,22889953 ! protein ubiquitination GO:0016567 217 97 0,000 0,230221 0,23089276 ! hormone metabolic process GO:0042445 157 97 0,000 0,230221 0,23079655 ! response to virus GO:0009615 160 98 0,000 0,23229802 0,23278177 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,23229802 0,23268486 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,2343695 0,2346621 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,2343695 0,23456448 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,2343695 0,23446695 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,23643546 0,23643546