pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/204-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cellular metabolic compound salvage GO:0043094 6 6 2,000 1,484E-06 2,734E-03 ! regulation of T cell activation GO:0050863 53 53 4,000 2,756E-06 2,539E-03 ! regulation of T cell proliferation GO:0042129 25 25 3,000 3,488E-06 2,143E-03 ! regulation of mast cell proliferation GO:0070666 28 28 3,000 5,594E-06 2,577E-03 ! regulation of lymphocyte activation GO:0051249 62 62 4,000 6,046E-06 2,229E-03 ! regulation of lymphocyte proliferation GO:0050670 29 29 3,000 6,469E-06 1,987E-03 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! purine ribonucleoside metabolic process GO:0046128 10 10 2,000 8,797E-06 2,316E-03 GO:0042278|purine nucleoside metabolic process, ! regulation of erythrocyte differentiation GO:0045646 10 10 2,000 8,797E-06 2,027E-03 ! regulation of lymphocyte differentiation GO:0045619 32 32 3,000 9,706E-06 1,988E-03 ! regulation of leukocyte activation GO:0002694 69 69 4,000 1,028E-05 1,894E-03 ! regulation of cell activation GO:0050865 71 71 4,000 1,184E-05 1,983E-03 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 2,000 2,078E-05 3,192E-03 ! positive regulation of T cell activation GO:0050870 39 39 3,000 2,174E-05 3,081E-03 ! positive regulation of lymphocyte activation GO:0051251 44 44 3,000 3,533E-05 4,651E-03 ! positive regulation of cell activation GO:0050867 49 49 3,000 5,432E-05 6,674E-03 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of T cell proliferation GO:0042102 19 19 2,000 6,917E-05 7,968E-03 ! ribonucleoside metabolic process GO:0009119 19 19 2,000 6,917E-05 7,499E-03 ! regulation of cell adhesion GO:0030155 56 55 3,000 8,586E-05 8,791E-03 ! extracellular structure organization GO:0043062 56 56 3,000 9,219E-05 8,942E-03 ! mammary gland development GO:0030879 23 21 2,000 9,439E-05 8,698E-03 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 2,000 1,09E-04 9,563E-03 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! positive regulation of lymphocyte differentiation GO:0045621 22 22 2,000 1,09E-04 9,129E-03 ! regulation of T cell differentiation GO:0045580 26 26 2,000 1,818E-04 0,01456943 ! regulation of cellular amine metabolic process GO:0033238 5 5 1,000 1,823E-04 0,01400166 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 1,823E-04 0,0134416 ! middle ear morphogenesis GO:0042474 5 5 1,000 1,823E-04 0,01292461 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 1,000 1,823E-04 0,01244592 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! cellular glucose homeostasis GO:0001678 5 5 1,000 1,823E-04 0,01200143 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 1,000 1,823E-04 0,01158758 GO:0009155|purine deoxyribonucleotide catabolic process, ! oocyte differentiation GO:0009994 5 5 1,000 1,823E-04 0,01120133 GO:0048599|oocyte development, ! blastocyst formation GO:0001825 5 5 1,000 1,823E-04 0,01084 ! embryonic gut development GO:0048566 5 5 1,000 1,823E-04 0,01050125 ! negative regulation of cell differentiation GO:0045596 68 67 3,000 1,861E-04 0,0103922 ! regulation of activated T cell proliferation GO:0046006 6 6 1,000 2,728E-04 0,01478508 ! succinate metabolic process GO:0006105 7 6 1,000 2,728E-04 0,01436265 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 2,728E-04 0,01396369 GO:0070667|negative regulation of mast cell proliferation, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 2,728E-04 0,01358629 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 2,728E-04 0,01322876 ! positive regulation of B cell differentiation GO:0045579 6 6 1,000 2,728E-04 0,01288956 ! regulation of myeloid cell differentiation GO:0045637 32 31 2,000 3,097E-04 0,01427173 ! nucleoside metabolic process GO:0009116 31 31 2,000 3,097E-04 0,01392364 ! extracellular matrix organization GO:0030198 31 31 2,000 3,097E-04 0,01359212 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 3,808E-04 0,01632237 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 1,000 3,808E-04 0,0159514 ! positive regulation of survival gene product expression GO:0045885 7 7 1,000 3,808E-04 0,01559693 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 3,808E-04 0,01525786 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 1,000 3,808E-04 0,01493323 ! response to estradiol stimulus GO:0032355 7 7 1,000 3,808E-04 0,01462212 ! natural killer cell activation GO:0030101 7 7 1,000 3,808E-04 0,01432371 ! positive regulation of protein polymerization GO:0032273 7 7 1,000 3,808E-04 0,01403723 ! negative regulation of T cell activation GO:0050868 7 7 1,000 3,808E-04 0,01376199 ! lymphocyte activation GO:0046649 82 81 3,000 3,871E-04 0,01372129 ! regulation of angiogenesis GO:0045765 35 34 2,000 4,087E-04 0,01421313 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 3,000 4,867E-04 0,01661153 ! lipid localization GO:0010876 8 8 1,000 5,064E-04 0,01696871 GO:0019915|lipid storage, ! phosphagen metabolic process GO:0006599 8 8 1,000 5,064E-04 0,01666569 GO:0006600|creatine metabolic process, ! nucleoside triphosphate catabolic process GO:0009143 8 8 1,000 5,064E-04 0,01637331 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 5,064E-04 0,01609101 ! T cell homeostasis GO:0043029 8 8 1,000 5,064E-04 0,01581828 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 5,064E-04 0,01555465 ! regulation of homeostatic process GO:0032844 38 38 2,000 5,695E-04 0,01720569 ! positive regulation of immune system process GO:0002684 92 92 3,000 6,289E-04 0,0186944 ! lactation GO:0007595 10 9 1,000 6,493E-04 0,01899489 ! positive regulation of protein complex assembly GO:0031334 9 9 1,000 6,493E-04 0,01869809 ! regulation of cell-cell adhesion GO:0022407 9 9 1,000 6,493E-04 0,01841043 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 1,000 6,493E-04 0,01813148 ! central nervous system neuron development GO:0021954 10 9 1,000 6,493E-04 0,01786086 ! collagen catabolic process GO:0030574 9 9 1,000 6,493E-04 0,0175982 ! purine base metabolic process GO:0006144 9 9 1,000 6,493E-04 0,01734316 ! estrogen receptor signaling pathway GO:0030520 9 9 1,000 6,493E-04 0,0170954 ! regulation of survival gene product expression GO:0045884 10 10 1,000 8,094E-04 0,02101119 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 1,000 8,094E-04 0,02071936 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! central nervous system neuron differentiation GO:0021953 11 10 1,000 8,094E-04 0,02043554 ! neuromuscular junction development GO:0007528 10 10 1,000 8,094E-04 0,02015938 ! regulation of B cell differentiation GO:0045577 10 10 1,000 8,094E-04 0,01989059 ! lymphocyte homeostasis GO:0002260 10 10 1,000 8,094E-04 0,01962887 ! gut development GO:0048565 10 10 1,000 8,094E-04 0,01937395 ! negative regulation of coagulation GO:0050819 11 10 1,000 8,094E-04 0,01912557 ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 9,866E-04 0,02301728 ! signal complex assembly GO:0007172 11 11 1,000 9,866E-04 0,02272956 ! activation of MAPKK activity GO:0000186 12 11 1,000 9,866E-04 0,02244895 ! cellular response to starvation GO:0009267 11 11 1,000 9,866E-04 0,02217518 ! regulation of interleukin-2 production GO:0032663 11 11 1,000 9,866E-04 0,02190801 ! oogenesis GO:0048477 11 11 1,000 9,866E-04 0,0216472 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 9,866E-04 0,02139253 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 1,001E-03 0,02144995 ! collagen metabolic process GO:0032963 12 12 1,000 1,181E-03 0,02501297 ! C21-steroid hormone metabolic process GO:0008207 13 12 1,000 1,181E-03 0,02472873 ! deoxyribonucleotide catabolic process GO:0009264 12 12 1,000 1,181E-03 0,02445088 ! regulation of steroid metabolic process GO:0019218 12 12 1,000 1,181E-03 0,0241792 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 1,181E-03 0,0239135 ! leukocyte differentiation GO:0002521 50 49 2,000 1,204E-03 0,02412245 ! gland development GO:0048732 51 49 2,000 1,204E-03 0,02386307 ! T cell activation GO:0042110 51 50 2,000 1,277E-03 0,02504251 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 1,000 1,392E-03 0,02699815 GO:0019692|deoxyribose phosphate metabolic process, ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 1,392E-03 0,02671692 ! multicellular organismal catabolic process GO:0044243 13 13 1,000 1,392E-03 0,02644149 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 1,000 1,392E-03 0,02617168 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! nucleobase metabolic process GO:0009112 13 13 1,000 1,392E-03 0,02590732 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 1,392E-03 0,02564824 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 1,392E-03 0,0253943 ! purine nucleotide catabolic process GO:0006195 13 13 1,000 1,392E-03 0,02514534 ! blastocyst development GO:0001824 13 13 1,000 1,392E-03 0,02490121 ! protein tetramerization GO:0051262 13 13 1,000 1,392E-03 0,02466177 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 1,619E-03 0,0284209 ! D-ribose metabolic process GO:0006014 14 14 1,000 1,619E-03 0,02815278 ! collagen fibril organization GO:0030199 14 14 1,000 1,619E-03 0,02788967 ! regulation of blood coagulation GO:0030193 15 14 1,000 1,619E-03 0,02763144 ! positive regulation of inflammatory response GO:0050729 14 14 1,000 1,619E-03 0,02737794 ! in utero embryonic development GO:0001701 55 55 2,000 1,685E-03 0,02822679 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 1,863E-03 0,03093678 ! deoxyribonucleotide metabolic process GO:0009262 15 15 1,000 1,863E-03 0,03066056 ! response to starvation GO:0042594 15 15 1,000 1,863E-03 0,03038923 ! leukocyte homeostasis GO:0001776 15 15 1,000 1,863E-03 0,03012266 ! positive regulation of B cell activation GO:0050871 15 15 1,000 1,863E-03 0,02986072 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,863E-03 0,0296033 ! protein homooligomerization GO:0051260 15 15 1,000 1,863E-03 0,02935028 ! positive regulation of cytoskeleton organization GO:0051495 16 16 1,000 2,124E-03 0,03316893 ! pentose metabolic process GO:0019321 16 16 1,000 2,124E-03 0,0328902 ! cellular response to nutrient levels GO:0031669 16 16 1,000 2,124E-03 0,03261611 ! regulation of coagulation GO:0050818 17 16 1,000 2,124E-03 0,03234656 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 2,4E-03 0,03626059 ! myelination GO:0042552 17 17 1,000 2,4E-03 0,03596579 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 2,4E-03 0,03567574 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 2,4E-03 0,03539033 ! embryonic organ development GO:0048568 17 17 1,000 2,4E-03 0,03510946 ! liver development GO:0001889 17 17 1,000 2,4E-03 0,03483301 ! regulation of response to external stimulus GO:0032101 65 64 2,000 2,606E-03 0,03751922 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 2,693E-03 0,03847524 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 1,000 2,693E-03 0,03817928 ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 1,000 2,693E-03 0,03788783 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,693E-03 0,03760081 ! ensheathment of neurons GO:0007272 18 18 1,000 2,693E-03 0,03731809 GO:0008366|axon ensheathment, ! Ras protein signal transduction GO:0007265 69 67 2,000 2,97E-03 0,04084676 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 3,002E-03 0,04097945 ! metanephros development GO:0001656 19 19 1,000 3,002E-03 0,04067813 ! positive regulation of T cell differentiation GO:0045582 19 19 1,000 3,002E-03 0,04038121 ! peripheral nervous system development GO:0007422 19 19 1,000 3,002E-03 0,04008859 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 3,002E-03 0,03980019 ! placenta development GO:0001890 19 19 1,000 3,002E-03 0,0395159 ! response to heat GO:0009408 19 19 1,000 3,002E-03 0,03923565 ! regulation of translation GO:0006417 69 69 2,000 3,229E-03 0,04191098 ! female gamete generation GO:0007292 20 20 1,000 3,326E-03 0,04286924 ! regulation of B cell activation GO:0050864 20 20 1,000 3,326E-03 0,04257154 ! wound healing GO:0042060 74 70 2,000 3,364E-03 0,0427561 ! negative regulation of signal transduction GO:0009968 71 71 2,000 3,502E-03 0,04420685 ! sensory organ development GO:0007423 72 72 2,000 3,644E-03 0,04568098 ! ear morphogenesis GO:0042471 21 21 1,000 3,666E-03 0,04565733 ! regulation of action potential in neuron GO:0019228 21 21 1,000 3,666E-03 0,04535091 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 3,666E-03 0,04504857 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 3,666E-03 0,04475023 ! cellular amide metabolic process GO:0043603 22 22 1,000 4,022E-03 0,04876928 ! embryonic skeletal system development GO:0048706 22 22 1,000 4,022E-03 0,04845053 ! ovulation cycle process GO:0022602 22 22 1,000 4,022E-03 0,04813591 ! male sex differentiation GO:0046661 22 22 1,000 4,022E-03 0,04782536 ! neuron migration GO:0001764 22 22 1,000 4,022E-03 0,04751879 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 4,022E-03 0,04721612 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 1,000 4,022E-03 0,04691728 ! negative regulation of cell communication GO:0010648 76 76 2,000 4,245E-03 0,04920196 ! response to estrogen stimulus GO:0043627 23 23 1,000 4,393E-03 0,05060621 ! positive regulation of growth GO:0045927 23 23 1,000 4,393E-03 0,05029188 ! female gonad development GO:0008585 23 23 1,000 4,393E-03 0,04998144 ! cell projection assembly GO:0030031 25 23 1,000 4,393E-03 0,0496748 ! regulation of action potential GO:0001508 24 24 1,000 4,78E-03 0,05371481 ! glucose homeostasis GO:0042593 24 24 1,000 4,78E-03 0,05338926 GO:0033500|carbohydrate homeostasis, ! nucleotide catabolic process GO:0009166 24 24 1,000 4,78E-03 0,05306764 ! ovulation cycle GO:0042698 24 24 1,000 4,78E-03 0,05274987 ! MAPKKK cascade GO:0000165 82 81 2,000 5,077E-03 0,05569356 ! regulation of actin filament polymerization GO:0030833 25 25 1,000 5,181E-03 0,0565053 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 5,181E-03 0,05617292 GO:0046660|female sex differentiation, ! negative regulation of immune system process GO:0002683 25 25 1,000 5,181E-03 0,05584442 ! JAK-STAT cascade GO:0007259 26 25 1,000 5,181E-03 0,05551974 ! positive regulation of defense response GO:0031349 26 26 1,000 5,598E-03 0,05963731 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 5,598E-03 0,05929456 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 1,000 5,598E-03 0,05895574 ! germ cell development GO:0007281 27 26 1,000 5,598E-03 0,05862076 ! response to insulin stimulus GO:0032868 28 26 1,000 5,598E-03 0,05828957 ! synapse organization GO:0050808 26 26 1,000 5,598E-03 0,0579621 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 5,809E-03 0,05980659 ! positive regulation of protein kinase activity GO:0045860 89 86 2,000 6,001E-03 0,06144388 ! cell growth GO:0016049 27 27 1,000 6,03E-03 0,06139538 ! positive regulation of transferase activity GO:0051347 91 88 2,000 6,397E-03 0,06478005 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 2,000 6,397E-03 0,06442606 ! protein amino acid autophosphorylation GO:0046777 28 28 1,000 6,476E-03 0,06486461 ! developmental growth GO:0048589 28 28 1,000 6,476E-03 0,06451399 ! positive regulation of cell cycle GO:0045787 29 29 1,000 6,937E-03 0,06873436 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 6,937E-03 0,0683668 ! regulation of protein polymerization GO:0032271 29 29 1,000 6,937E-03 0,06800315 ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 7,412E-03 0,07227957 ! skeletal system morphogenesis GO:0048705 31 30 1,000 7,412E-03 0,07189915 ! response to temperature stimulus GO:0009266 30 30 1,000 7,412E-03 0,07152271 ! regulation of inflammatory response GO:0050727 30 30 1,000 7,412E-03 0,0711502 ! regulation of response to stress GO:0080134 97 94 2,000 7,678E-03 0,07332128 ! regulation of translational initiation GO:0006446 31 31 1,000 7,902E-03 0,07507008 ! skeletal muscle fiber development GO:0048741 31 31 1,000 7,902E-03 0,0746851 ! camera-type eye development GO:0043010 31 31 1,000 7,902E-03 0,07430405 ! negative regulation of cell growth GO:0030308 32 32 1,000 8,406E-03 0,07864279 ! muscle fiber development GO:0048747 32 32 1,000 8,406E-03 0,0782456 ! kidney development GO:0001822 32 32 1,000 8,406E-03 0,07785241 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 8,611E-03 0,0793502 ! anti-apoptosis GO:0006916 100 99 2,000 8,854E-03 0,0811851 ! negative regulation of cell size GO:0045792 33 33 1,000 8,924E-03 0,08142432 ! activation of protein kinase activity GO:0032147 35 33 1,000 8,924E-03 0,08102321 ! regulation of protein complex assembly GO:0043254 33 33 1,000 8,924E-03 0,08062604 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 1,000 8,924E-03 0,08023274 ! response to hormone stimulus GO:0009725 102 100 2,000 9,101E-03 0,08142616 ! hemopoiesis GO:0030097 104 100 2,000 9,101E-03 0,08103279 ! ear development GO:0043583 34 34 1,000 9,457E-03 0,08379141 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 9,457E-03 0,08339049 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 9,457E-03 0,08299339 ! regulation of actin filament length GO:0030832 34 34 1,000 9,457E-03 0,08260006 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 9,457E-03 0,08221044 ! regulation of cellular component size GO:0032535 35 35 1,000 0,01000277 0,08654979 ! regulation of cytokine biosynthetic process GO:0042035 35 35 1,000 0,01000277 0,08614535 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,01000277 0,08574467 GO:0048609|reproductive process in a multicellular organism, ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,01000277 0,08534771 ! positive regulation of cell migration GO:0030335 36 36 1,000 0,01056265 0,0897095 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,01056265 0,08929799 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 1,000 0,01056265 0,08889023 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,01056265 0,08848619 ! heterocycle catabolic process GO:0046700 36 36 1,000 0,01056265 0,0880858 ! gonad development GO:0008406 36 36 1,000 0,01056265 0,08768901 ! coagulation GO:0050817 39 36 1,000 0,01056265 0,08729579 GO:0007596|blood coagulation, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,01113617 0,09162481 ! lung development GO:0030324 38 37 1,000 0,01113617 0,09121758 ! eye development GO:0001654 37 37 1,000 0,01113617 0,09081397 ! negative regulation of growth GO:0045926 37 37 1,000 0,01113617 0,09041391 ! cellular hormone metabolic process GO:0034754 39 38 1,000 0,01172321 0,09476258 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,01172321 0,09434877 ! urogenital system development GO:0001655 38 38 1,000 0,01172321 0,09393856 ! axon guidance GO:0007411 39 38 1,000 0,01172321 0,0935319 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,01172321 0,09312874 ! hemostasis GO:0007599 42 39 1,000 0,01232364 0,09747843 ! respiratory tube development GO:0030323 40 39 1,000 0,01232364 0,09706185 ! response to unfolded protein GO:0006986 39 39 1,000 0,01232364 0,09664882 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 0,01232364 0,09623929 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,01232364 0,09583322 ! respiratory system development GO:0060541 40 39 1,000 0,01232364 0,09543056 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,01232364 0,09503127 ! limb development GO:0060173 39 39 1,000 0,01232364 0,09463531 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 1,000 0,01232364 0,09424263 ! positive regulation of cell motion GO:0051272 39 39 1,000 0,01232364 0,0938532 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,01293736 0,09812161 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,01293736 0,09771947 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,01293736 0,09732062 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,01420415 0,10641564 ! response to protein stimulus GO:0051789 42 42 1,000 0,01420415 0,10598481 ! reproductive structure development GO:0048608 43 43 1,000 0,01485699 0,110409 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,01485699 0,10996559 ! mRNA transport GO:0051028 44 44 1,000 0,01552264 0,11443288 ! protein import into nucleus GO:0006606 44 44 1,000 0,01552264 0,11397697 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,01620097 0,11848569 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,01620097 0,11801737 ! nuclear import GO:0051170 45 45 1,000 0,01620097 0,11755273 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,01689188 0,12208527 ! regulation of membrane potential GO:0042391 46 46 1,000 0,01689188 0,12160837 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,01759526 0,12617921 ! sex differentiation GO:0007548 47 47 1,000 0,01759526 0,12569014 ! rhythmic process GO:0048511 47 47 1,000 0,01759526 0,12520485 ! actin filament organization GO:0007015 50 48 1,000 0,01831097 0,12979663 ! protein localization in nucleus GO:0034504 48 48 1,000 0,01831097 0,12929932 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,01903892 0,13392647 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 0,01903892 0,13341724 ! regulation of defense response GO:0031347 50 50 1,000 0,01977899 0,13807834 ! RNA transport GO:0050658 50 50 1,000 0,01977899 0,13755729 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 1,000 0,01977899 0,13704016 ! RNA localization GO:0006403 52 52 1,000 0,02129504 0,14699162 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,02129504 0,14644314 ! rRNA transcription GO:0009303 5 5 0,000 0,02161925 0,14811997 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02161925 0,14757138 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02161925 0,14702684 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02161925 0,1464863 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02161925 0,14594972 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02161925 0,14541705 ! reproductive cellular process GO:0048610 5 5 0,000 0,02161925 0,14488826 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,02161925 0,14436331 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02161925 0,14384214 ! prostate gland development GO:0030850 5 5 0,000 0,02161925 0,14332472 ! metencephalon development GO:0022037 5 5 0,000 0,02161925 0,14281101 ! water transport GO:0006833 5 5 0,000 0,02161925 0,14230097 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02161925 0,14179456 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02161925 0,14129175 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02161925 0,14079248 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02161925 0,14029673 ! meiotic prophase I GO:0007128 5 5 0,000 0,02161925 0,13980446 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02161925 0,13931564 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02161925 0,13883022 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02161925 0,13834817 ! filopodium assembly GO:0046847 7 5 0,000 0,02161925 0,13786945 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02161925 0,13739404 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02161925 0,1369219 ! GTP metabolic process GO:0046039 5 5 0,000 0,02161925 0,13645299 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02161925 0,13598728 ! mRNA stabilization GO:0048255 5 5 0,000 0,02161925 0,13552474 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02161925 0,13506533 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02161925 0,13460903 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02161925 0,1341558 ! social behavior GO:0035176 5 5 0,000 0,02161925 0,13370561 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02161925 0,13325844 ! memory GO:0007613 5 5 0,000 0,02161925 0,13281424 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02161925 0,132373 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02161925 0,13193468 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02161925 0,13149925 ! response to lipid GO:0033993 5 5 0,000 0,02161925 0,13106669 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02161925 0,13063696 ! hippocampus development GO:0021766 6 5 0,000 0,02161925 0,13021004 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02161925 0,1297859 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02161925 0,12936452 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02161925 0,12894587 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02161925 0,12852991 ! heart looping GO:0001947 5 5 0,000 0,02161925 0,12811663 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02161925 0,127706 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02161925 0,12729799 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02161925 0,12689259 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02161925 0,12648975 ! pH reduction GO:0045851 5 5 0,000 0,02161925 0,12608947 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02161925 0,12569171 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02161925 0,12529645 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02161925 0,12490368 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02161925 0,12451335 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02161925 0,12412546 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02161925 0,12373998 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02161925 0,12335688 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02161925 0,12297615 ! adrenal gland development GO:0030325 5 5 0,000 0,02161925 0,12259776 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02161925 0,12222169 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02161925 0,12184793 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02161925 0,12147644 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02161925 0,12110721 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02161925 0,12074022 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02161925 0,12037545 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02161925 0,12001287 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02161925 0,11965247 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02161925 0,11929423 ! microtubule nucleation GO:0007020 5 5 0,000 0,02161925 0,11893813 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02161925 0,11858414 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02161925 0,11823226 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02161925 0,11788246 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02161925 0,11753473 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02161925 0,11718904 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02161925 0,11684537 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02161925 0,11650372 ! response to ATP GO:0033198 5 5 0,000 0,02161925 0,11616406 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02161925 0,11582637 ! regulation of appetite GO:0032098 5 5 0,000 0,02161925 0,11549064 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02161925 0,11515686 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02161925 0,11482499 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,02161925 0,11449504 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02161925 0,11416697 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02161925 0,11384078 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02161925 0,11351645 ! receptor clustering GO:0043113 5 5 0,000 0,02161925 0,11319396 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02161925 0,11287329 ! fear response GO:0042596 5 5 0,000 0,02161925 0,11255444 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02161925 0,11223739 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02161925 0,11192211 ! retinol metabolic process GO:0042572 5 5 0,000 0,02161925 0,11160861 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02161925 0,11129685 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02161925 0,11098683 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02161925 0,11067853 ! parturition GO:0007567 5 5 0,000 0,02161925 0,11037195 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02161925 0,11006705 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02161925 0,10976384 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02161925 0,10946229 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02161925 0,10916239 ! protein heterooligomerization GO:0051291 5 5 0,000 0,02161925 0,10886413 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02161925 0,1085675 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02161925 0,10827248 ! response to UV-B GO:0010224 5 5 0,000 0,02161925 0,10797906 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02161925 0,10768722 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02161925 0,10739696 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02161925 0,10710826 ! interaction with symbiont GO:0051702 5 5 0,000 0,02161925 0,10682111 ! cellular extravasation GO:0045123 5 5 0,000 0,02161925 0,10653549 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02161925 0,10625139 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02161925 0,10596881 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02161925 0,10568773 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02161925 0,10540813 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02161925 0,10513001 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02161925 0,10485335 ! response to amine stimulus GO:0014075 5 5 0,000 0,02161925 0,10457814 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02161925 0,10430438 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02161925 0,10403204 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02161925 0,10376113 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02161925 0,10349162 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02161925 0,1032235 ! neuron recognition GO:0008038 5 5 0,000 0,02161925 0,10295678 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02161925 0,10269142 ! decidualization GO:0046697 5 5 0,000 0,02161925 0,10242744 ! hair follicle maturation GO:0048820 5 5 0,000 0,02161925 0,1021648 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02161925 0,10190351 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02161925 0,10164355 ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02161925 0,10138492 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02161925 0,10112759 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02161925 0,10087158 ! postreplication repair GO:0006301 5 5 0,000 0,02161925 0,10061685 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02161925 0,10036341 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02161925 0,10011124 ! histone methylation GO:0016571 5 5 0,000 0,02161925 0,09986033 ! DNA methylation GO:0006306 5 5 0,000 0,02161925 0,09961068 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02161925 0,09936228 ! T cell lineage commitment GO:0002360 5 5 0,000 0,02161925 0,09911511 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02161925 0,09886916 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02161925 0,09862444 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02161925 0,09838092 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02161925 0,0981386 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02161925 0,09789748 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02161925 0,09765753 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02161925 0,09741876 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02161925 0,09718115 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02161925 0,0969447 ! sterol catabolic process GO:0016127 5 5 0,000 0,02161925 0,0967094 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02161925 0,09647524 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02161925 0,0962422 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02161925 0,09601029 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02161925 0,0957795 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02161925 0,09554981 ! zymogen activation GO:0031638 5 5 0,000 0,02161925 0,09532123 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02161925 0,09509373 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02161925 0,09486732 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02161925 0,09464198 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,02161925 0,09441771 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,02161925 0,0941945 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02161925 0,09397234 ! nucleosome positioning GO:0016584 5 5 0,000 0,02161925 0,09375123 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02161925 0,09353116 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02161925 0,09331211 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02161925 0,09309409 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02161925 0,09287709 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02161925 0,0926611 ! NADPH regeneration GO:0006740 5 5 0,000 0,02161925 0,09244611 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02161925 0,09223211 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02161925 0,0920191 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02161925 0,09180708 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02161925 0,09159603 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02161925 0,09138595 ! sarcomere organization GO:0045214 5 5 0,000 0,02161925 0,09117682 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02161925 0,09096866 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02161925 0,09076144 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02161925 0,09055516 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02161925 0,09034982 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02161925 0,09014541 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02161925 0,08994192 ! spleen development GO:0048536 5 5 0,000 0,02161925 0,08973935 ! male genitalia development GO:0030539 5 5 0,000 0,02161925 0,08953769 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02161925 0,08933693 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02161925 0,08913707 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02161925 0,08893811 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02161925 0,08874003 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02161925 0,08854283 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02161925 0,0883465 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02161925 0,08815104 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02161925 0,08795645 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02161925 0,08776271 ! ATP catabolic process GO:0006200 5 5 0,000 0,02161925 0,08756983 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02161925 0,08737779 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02161925 0,08718659 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02161925 0,08699623 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02161925 0,08680669 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02161925 0,08661798 ! activation of innate immune response GO:0002218 5 5 0,000 0,02161925 0,08643009 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02161925 0,08624301 ! catecholamine transport GO:0051937 5 5 0,000 0,02161925 0,08605674 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02161925 0,08587128 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02161925 0,08568661 ! muscle adaptation GO:0043500 5 5 0,000 0,02161925 0,08550273 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02161925 0,08531964 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02161925 0,08513733 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02161925 0,0849558 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02161925 0,08477505 ! defense response to fungus GO:0050832 5 5 0,000 0,02161925 0,08459506 ! lysogeny GO:0030069 5 5 0,000 0,02161925 0,08441583 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02161925 0,08423736 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02161925 0,08405965 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02161925 0,08388268 ! response to nicotine GO:0035094 5 5 0,000 0,02161925 0,08370645 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02161925 0,08353097 ! mitochondrion localization GO:0051646 5 5 0,000 0,02161925 0,08335622 ! nucleus localization GO:0051647 5 5 0,000 0,02161925 0,0831822 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02161925 0,0830089 ! response to hypoxia GO:0001666 53 53 1,000 0,0220708 0,0845665 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 0,0220708 0,08439105 ! response to oxygen levels GO:0070482 55 54 1,000 0,02285823 0,08722096 ! hormone metabolic process GO:0042445 55 54 1,000 0,02285823 0,08704076 ! sulfur metabolic process GO:0006790 55 54 1,000 0,02285823 0,08686129 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,02285823 0,08668256 ! reproductive developmental process GO:0003006 56 56 1,000 0,02446769 0,0925954 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02588854 0,0977717 ! axon extension GO:0048675 7 6 0,000 0,02588854 0,09757176 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02588854 0,09737263 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,02588854 0,09717431 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,02588854 0,09697681 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02588854 0,0967801 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02588854 0,09658419 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02588854 0,09638907 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02588854 0,09619473 ! virus-host interaction GO:0019048 6 6 0,000 0,02588854 0,09600118 ! regulation of S phase GO:0033261 6 6 0,000 0,02588854 0,09580841 ! myotube differentiation GO:0014902 6 6 0,000 0,02588854 0,09561641 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02588854 0,09542518 ! bone remodeling GO:0046849 6 6 0,000 0,02588854 0,09523471 ! N-glycan processing GO:0006491 6 6 0,000 0,02588854 0,095045 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02588854 0,09485604 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02588854 0,09466783 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02588854 0,09448037 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02588854 0,09429365 ! RNA methylation GO:0001510 6 6 0,000 0,02588854 0,09410767 ! cartilage condensation GO:0001502 7 6 0,000 0,02588854 0,09392242 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02588854 0,09373789 GO:0050927|positive regulation of positive chemotaxis, ! artery development GO:0060840 6 6 0,000 0,02588854 0,09355409 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02588854 0,09337101 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02588854 0,09318865 ! androgen metabolic process GO:0008209 6 6 0,000 0,02588854 0,09300699 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02588854 0,09282605 ! limbic system development GO:0021761 7 6 0,000 0,02588854 0,0926458 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02588854 0,09246626 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,02588854 0,0922874 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02588854 0,09210924 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02588854 0,09193177 ! pathogenesis GO:0009405 6 6 0,000 0,02588854 0,09175498 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02588854 0,09157886 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02588854 0,09140343 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02588854 0,09122866 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02588854 0,09105456 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02588854 0,09088112 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02588854 0,09070834 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02588854 0,09053622 ! arginine metabolic process GO:0006525 6 6 0,000 0,02588854 0,09036475 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02588854 0,09019393 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02588854 0,09002375 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02588854 0,08985422 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02588854 0,08968532 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02588854 0,08951705 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02588854 0,08934942 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02588854 0,08918241 ! ER overload response GO:0006983 6 6 0,000 0,02588854 0,08901602 ! V(D)J recombination GO:0033151 6 6 0,000 0,02588854 0,08885026 ! focal adhesion formation GO:0048041 7 6 0,000 0,02588854 0,08868511 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02588854 0,08852057 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02588854 0,08835664 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02588854 0,08819332 ! regulation of heart rate GO:0002027 6 6 0,000 0,02588854 0,08803061 ! lipid digestion GO:0044241 6 6 0,000 0,02588854 0,08786849 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02588854 0,08770696 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02588854 0,08754603 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02588854 0,08738569 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02588854 0,08722594 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02588854 0,08706677 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02588854 0,08690818 ! ruffle organization GO:0031529 6 6 0,000 0,02588854 0,08675016 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02588854 0,08659272 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02588854 0,08643585 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02588854 0,08627954 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02588854 0,08612381 ! L-amino acid transport GO:0015807 6 6 0,000 0,02588854 0,08596863 ! bone mineralization GO:0030282 6 6 0,000 0,02588854 0,08581401 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02588854 0,08565994 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02588854 0,08550643 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02588854 0,08535347 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02588854 0,08520105 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02588854 0,08504918 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02588854 0,08489784 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,02588854 0,08474705 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02588854 0,08459679 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02588854 0,08444706 ! regulation of organ growth GO:0046620 6 6 0,000 0,02588854 0,08429786 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02588854 0,08414919 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02588854 0,08400104 ! response to dsRNA GO:0043331 6 6 0,000 0,02588854 0,08385341 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02588854 0,0837063 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02588854 0,0835597 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02588854 0,08341362 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02588854 0,08326804 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02588854 0,08312298 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02588854 0,08297841 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02588854 0,08283435 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02588854 0,08269079 ! erythrocyte development GO:0048821 6 6 0,000 0,02588854 0,08254773 ! renal water homeostasis GO:0003091 6 6 0,000 0,02588854 0,08240516 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02588854 0,08226308 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02588854 0,08212149 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02588854 0,08198039 ! ribosome assembly GO:0042255 6 6 0,000 0,02588854 0,08183977 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02588854 0,08169964 ! diencephalon development GO:0021536 6 6 0,000 0,02588854 0,08155998 ! fucose catabolic process GO:0019317 6 6 0,000 0,02588854 0,0814208 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02588854 0,08128209 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02588854 0,08114386 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02588854 0,08100609 ! regulation of cell division GO:0051302 6 6 0,000 0,02588854 0,08086879 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02588854 0,08073196 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02588854 0,08059559 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02588854 0,08045968 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02588854 0,08032422 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02588854 0,08018922 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02588854 0,08005468 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02588854 0,07992058 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02588854 0,07978694 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02588854 0,07965374 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02588854 0,07952098 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02588854 0,07938867 ! thymus development GO:0048538 6 6 0,000 0,02588854 0,07925679 ! lymph node development GO:0048535 6 6 0,000 0,02588854 0,07912535 ! organic cation transport GO:0015695 6 6 0,000 0,02588854 0,07899435 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02588854 0,07886378 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02588854 0,07873364 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,02588854 0,07860393 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02588854 0,07847465 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02588854 0,07834579 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02588854 0,07821736 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02588854 0,07808934 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02588854 0,07796175 ! alditol metabolic process GO:0019400 6 6 0,000 0,02588854 0,07783456 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02588854 0,0777078 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02588854 0,07758144 ! maternal placenta development GO:0001893 6 6 0,000 0,02588854 0,0774555 ! regulation of embryonic development GO:0045995 6 6 0,000 0,02588854 0,07732996 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02588854 0,07720484 ! localization within membrane GO:0051668 6 6 0,000 0,02588854 0,07708011 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,02696674 0,0801608 ! protein localization in organelle GO:0033365 59 59 1,000 0,02696674 0,08003172 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,02868809 0,08500346 ! axonogenesis GO:0007409 66 62 1,000 0,02956505 0,0874613 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,02956505 0,08732114 ! protein import GO:0017038 62 62 1,000 0,02956505 0,08718143 ! respiratory burst GO:0045730 7 7 0,000 0,03013983 0,08873436 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,03013983 0,08859284 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,03013983 0,08845177 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,03013983 0,08831114 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,03013983 0,08817097 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,03013983 0,08803124 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,03013983 0,08789195 ! regulation of chemokine production GO:0032642 7 7 0,000 0,03013983 0,0877531 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,03013983 0,08761468 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,03013983 0,08747671 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,03013983 0,08733917 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,03013983 0,08720206 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,03013983 0,08706538 ! gene silencing by RNA GO:0031047 7 7 0,000 0,03013983 0,08692912 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,03013983 0,0867933 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,03013983 0,08665789 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,03013983 0,08652291 ! axis specification GO:0009798 7 7 0,000 0,03013983 0,08638835 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,03013983 0,08625421 ! visual behavior GO:0007632 7 7 0,000 0,03013983 0,08612048 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,03013983 0,08598717 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,03013983 0,08585426 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,03013983 0,08572177 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,03013983 0,08558969 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,03013983 0,08545801 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,03013983 0,08532674 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,03013983 0,08519587 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,03013983 0,0850654 ! digestive system development GO:0055123 7 7 0,000 0,03013983 0,08493534 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,03013983 0,08480566 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,03013983 0,08467639 ! protein targeting to ER GO:0045047 8 7 0,000 0,03013983 0,0845475 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,03013983 0,08441901 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,03013983 0,08429091 ! endoderm development GO:0007492 7 7 0,000 0,03013983 0,0841632 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,03013983 0,08403587 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,03013983 0,08390893 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,03013983 0,08378237 ! response to hexose stimulus GO:0009746 7 7 0,000 0,03013983 0,08365619 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,03013983 0,08353039 GO:0033619|membrane protein proteolysis, ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,03013983 0,08340497 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,03013983 0,08327992 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,03013983 0,08315525 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,03013983 0,08303096 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,03013983 0,08290703 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,03013983 0,08278347 ! response to X-ray GO:0010165 7 7 0,000 0,03013983 0,08266028 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,03013983 0,08253746 ! UV protection GO:0009650 7 7 0,000 0,03013983 0,082415 ! DNA integration GO:0015074 7 7 0,000 0,03013983 0,0822929 ! myofibril assembly GO:0030239 7 7 0,000 0,03013983 0,08217117 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,03013983 0,08204979 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,03013983 0,08192877 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,03013983 0,08180811 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,03013983 0,08168781 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,03013983 0,08156786 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,03013983 0,08144825 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,03013983 0,081329 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,03013983 0,0812101 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,03013983 0,08109155 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,03013983 0,08097334 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,03013983 0,08085547 ! axon cargo transport GO:0008088 7 7 0,000 0,03013983 0,08073795 ! eating behavior GO:0042755 7 7 0,000 0,03013983 0,08062077 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,03013983 0,08050393 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,03013983 0,08038742 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,03013983 0,08027126 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,03013983 0,08015542 ! cranial nerve development GO:0021545 7 7 0,000 0,03013983 0,08003993 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,03013983 0,07992476 ! induction of an organ GO:0001759 7 7 0,000 0,03013983 0,07980993 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,03013983 0,07969542 GO:0002263|cell activation during immune response, ! autonomic nervous system development GO:0048483 7 7 0,000 0,03013983 0,07958125 ! intracellular lipid transport GO:0032365 7 7 0,000 0,03013983 0,0794674 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,03013983 0,07935387 ! platelet activation GO:0030168 8 7 0,000 0,03013983 0,07924067 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,03013983 0,07912779 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,03013983 0,07901523 ! response to gamma radiation GO:0010332 8 7 0,000 0,03013983 0,078903 ! NADP metabolic process GO:0006739 7 7 0,000 0,03013983 0,07879108 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,03013983 0,07867947 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,03013983 0,07856819 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,03013983 0,07845722 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,03013983 0,07834656 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,03013983 0,07823621 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,03013983 0,07812617 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,03013983 0,07801645 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,03013983 0,07790703 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,03013983 0,07779791 ! cell-cell recognition GO:0009988 8 7 0,000 0,03013983 0,0776891 ! hormone catabolic process GO:0042447 7 7 0,000 0,03013983 0,0775806 ! dopamine metabolic process GO:0042417 7 7 0,000 0,03013983 0,0774724 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,03013983 0,0773645 ! oxygen transport GO:0015671 7 7 0,000 0,03013983 0,0772569 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,03013983 0,0771496 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,03013983 0,07704259 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,03013983 0,07693589 ! regulation of axon extension GO:0030516 7 7 0,000 0,03013983 0,07682947 ! cell killing GO:0001906 7 7 0,000 0,03013983 0,07672336 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,03013983 0,07661753 ! adult feeding behavior GO:0008343 7 7 0,000 0,03013983 0,076512 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,03013983 0,07640675 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,03013983 0,0763018 ! response to cold GO:0009409 7 7 0,000 0,03013983 0,07619713 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 1,000 0,03045273 0,07688271 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,03135102 0,0790423 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,03135102 0,07893432 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,03225982 0,08111165 ! regulation of hormone levels GO:0010817 66 65 1,000 0,03225982 0,08100114 ! nucleoside triphosphate metabolic process GO:0009141 66 66 1,000 0,03317902 0,08319583 ! regulation of MAP kinase activity GO:0043405 67 66 1,000 0,03317902 0,08308279 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,03410853 0,08529447 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 1,000 0,03410853 0,0851789 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,03437318 0,08572364 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,03437318 0,0856078 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,03437318 0,08549227 ! positive regulation of translation GO:0045727 8 8 0,000 0,03437318 0,08537705 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,03437318 0,08526214 ! superoxide anion generation GO:0042554 8 8 0,000 0,03437318 0,08514754 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,03437318 0,08503325 ! cGMP metabolic process GO:0046068 8 8 0,000 0,03437318 0,08491926 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,03437318 0,08480558 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,03437318 0,08469221 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,03437318 0,08457913 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,03437318 0,08446636 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,03437318 0,08435389 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,03437318 0,08424172 ! zinc ion transport GO:0006829 8 8 0,000 0,03437318 0,08412984 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,03437318 0,08401826 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,03437318 0,08390698 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,03437318 0,08379599 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,03437318 0,0836853 ! response to pain GO:0048265 8 8 0,000 0,03437318 0,0835749 ! response to cAMP GO:0051591 8 8 0,000 0,03437318 0,08346478 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,03437318 0,08335496 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,03437318 0,08324543 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,03437318 0,08313618 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,03437318 0,08302722 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,03437318 0,08291855 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,03437318 0,08281016 ! sensory perception of taste GO:0050909 8 8 0,000 0,03437318 0,08270205 ! organelle fusion GO:0048284 8 8 0,000 0,03437318 0,08259423 ! pancreas development GO:0031016 8 8 0,000 0,03437318 0,08248668 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,03437318 0,08237942 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,03437318 0,08227243 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,03437318 0,08216572 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,03437318 0,08205929 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,03437318 0,08195313 ! sperm motility GO:0030317 8 8 0,000 0,03437318 0,08184725 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,03437318 0,08174164 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,03437318 0,0816363 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,03437318 0,08153124 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,03437318 0,08142644 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,03437318 0,08132191 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,03437318 0,08121765 ! Golgi organization GO:0007030 8 8 0,000 0,03437318 0,08111366 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,03437318 0,08100994 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,03437318 0,08090648 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,03437318 0,08080328 ! fructose metabolic process GO:0006000 8 8 0,000 0,03437318 0,08070035 ! mannose metabolic process GO:0006013 9 8 0,000 0,03437318 0,08059767 ! NAD metabolic process GO:0019674 8 8 0,000 0,03437318 0,08049526 ! sex determination GO:0007530 8 8 0,000 0,03437318 0,08039311 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,03437318 0,08029122 ! plasma membrane fusion GO:0045026 8 8 0,000 0,03437318 0,08018958 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,03437318 0,08008821 ! response to fungus GO:0009620 8 8 0,000 0,03437318 0,07998708 ! stem cell differentiation GO:0048863 8 8 0,000 0,03437318 0,07988622 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,03437318 0,07978561 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,03437318 0,07968525 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,03437318 0,07958514 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,03437318 0,07948528 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,03437318 0,07938568 ! regulation of vasodilation GO:0042312 8 8 0,000 0,03437318 0,07928632 ! vasoconstriction GO:0042310 8 8 0,000 0,03437318 0,07918721 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,03437318 0,07908835 ! muscle cell development GO:0055001 8 8 0,000 0,03437318 0,07898974 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,03437318 0,07889137 ! sensory perception of pain GO:0019233 8 8 0,000 0,03437318 0,07879325 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,03437318 0,07869537 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,03437318 0,07859773 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,03437318 0,07850034 ! chromatin silencing GO:0006342 8 8 0,000 0,03437318 0,07840318 ! tissue regeneration GO:0042246 8 8 0,000 0,03437318 0,07830627 ! salivary gland development GO:0007431 8 8 0,000 0,03437318 0,07820959 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,03437318 0,07811316 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,03437318 0,07801696 ! water homeostasis GO:0030104 8 8 0,000 0,03437318 0,077921 ! cofactor transport GO:0051181 8 8 0,000 0,03437318 0,07782527 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,03437318 0,07772978 ! acid secretion GO:0046717 8 8 0,000 0,03437318 0,07763452 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,03437318 0,0775395 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,03437318 0,07744471 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,03437318 0,07735015 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,03437318 0,07725582 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,03437318 0,07716172 ! regulation of RNA stability GO:0043487 8 8 0,000 0,03437318 0,07706785 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,03437318 0,07697421 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,03437318 0,07688079 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,03437318 0,0767876 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,03437318 0,07669464 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,03437318 0,0766019 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,03437318 0,07650939 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,03437318 0,07641709 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,03437318 0,07632503 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,03437318 0,07623318 ! developmental induction GO:0031128 8 8 0,000 0,03437318 0,07614155 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,03437318 0,07605015 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,03437318 0,07595896 ! actin filament polymerization GO:0030041 9 8 0,000 0,03437318 0,07586799 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,03437318 0,07577724 ! peptide hormone processing GO:0016486 8 8 0,000 0,03437318 0,0756867 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,03437318 0,07559639 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,03437318 0,07550628 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 1,000 0,03504825 0,07689753 ! regulation of cell size GO:0008361 68 68 1,000 0,03504825 0,0768061 ! regionalization GO:0003002 70 69 1,000 0,03599808 0,07879389 ! response to nutrient levels GO:0031667 69 69 1,000 0,03599808 0,07870042 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,03599808 0,07860717 ! cell part morphogenesis GO:0032990 75 70 1,000 0,0369579 0,08060759 ! growth GO:0040007 70 70 1,000 0,0369579 0,08051231 ! muscle tissue development GO:0060537 72 70 1,000 0,0369579 0,08041726 ! regulation of cell migration GO:0030334 71 71 1,000 0,03792764 0,08243 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03858866 0,08376785 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03858866 0,0836693 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03858866 0,08357098 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03858866 0,0834729 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03858866 0,08337504 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03858866 0,08327741 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,03858866 0,08318001 ! viral genome replication GO:0019079 9 9 0,000 0,03858866 0,08308284 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03858866 0,08298589 ! copper ion transport GO:0006825 9 9 0,000 0,03858866 0,08288917 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03858866 0,08279267 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03858866 0,0826964 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03858866 0,08260036 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03858866 0,08250453 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03858866 0,08240893 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03858866 0,08231355 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03858866 0,08221839 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03858866 0,08212345 ! phospholipid efflux GO:0033700 9 9 0,000 0,03858866 0,08202873 ! response to alkaloid GO:0043279 10 9 0,000 0,03858866 0,08193423 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03858866 0,08183994 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03858866 0,08174587 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03858866 0,08165202 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03858866 0,08155838 ! response to ethanol GO:0045471 9 9 0,000 0,03858866 0,08146496 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,03858866 0,08137175 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03858866 0,08127875 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03858866 0,08118597 ! methionine metabolic process GO:0006555 9 9 0,000 0,03858866 0,0810934 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03858866 0,08100103 ! cerebral cortex development GO:0021987 9 9 0,000 0,03858866 0,08090888 ! response to osmotic stress GO:0006970 9 9 0,000 0,03858866 0,08081694 ! pigmentation during development GO:0048066 9 9 0,000 0,03858866 0,08072521 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03858866 0,08063368 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03858866 0,08054236 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03858866 0,08045125 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03858866 0,08036035 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03858866 0,08026965 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03858866 0,08017915 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03858866 0,08008886 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03858866 0,07999877 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03858866 0,07990888 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03858866 0,0798192 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03858866 0,07972972 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03858866 0,07964043 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03858866 0,07955135 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03858866 0,07946247 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03858866 0,07937378 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,03858866 0,07928529 ! DNA replication initiation GO:0006270 9 9 0,000 0,03858866 0,079197 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03858866 0,07910891 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03858866 0,07902101 ! regulation of cellular pH GO:0030641 9 9 0,000 0,03858866 0,0789333 ! histone acetylation GO:0016573 9 9 0,000 0,03858866 0,0788458 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03858866 0,07875848 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03858866 0,07867136 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03858866 0,07858443 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03858866 0,07849769 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03858866 0,07841114 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03858866 0,07832479 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,03858866 0,07823862 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03858866 0,07815265 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03858866 0,07806686 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03858866 0,07798126 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03858866 0,07789585 ! gas transport GO:0015669 9 9 0,000 0,03858866 0,07781062 ! cholesterol efflux GO:0033344 9 9 0,000 0,03858866 0,07772558 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03858866 0,07764073 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03858866 0,07755606 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03858866 0,07747158 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03858866 0,07738728 ! defense response to virus GO:0051607 9 9 0,000 0,03858866 0,07730316 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03858866 0,07721923 ! actin filament-based movement GO:0030048 9 9 0,000 0,03858866 0,07713547 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03858866 0,0770519 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,03890719 0,07760383 ! regulation of cytokine production GO:0001817 72 72 1,000 0,03890719 0,07751994 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,0419037 0,08340012 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,0419037 0,08331016 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,04278636 0,08497333 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,04278636 0,08488187 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,04278636 0,0847906 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,04278636 0,08469952 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,04278636 0,08460864 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,04278636 0,08451796 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,04278636 0,08442747 ! neuron maturation GO:0042551 10 10 0,000 0,04278636 0,08433717 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,04278636 0,08424707 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,04278636 0,08415715 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,04278636 0,08406743 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,04278636 0,08397791 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,04278636 0,08388857 ! hormone secretion GO:0046879 10 10 0,000 0,04278636 0,08379942 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,04278636 0,08371046 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,04278636 0,08362169 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,04278636 0,08353311 ! inositol metabolic process GO:0006020 10 10 0,000 0,04278636 0,08344471 ! cAMP metabolic process GO:0046058 10 10 0,000 0,04278636 0,0833565 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,04278636 0,08326848 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,04278636 0,08318065 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,04278636 0,083093 ! glial cell development GO:0021782 10 10 0,000 0,04278636 0,08300553 ! phototransduction GO:0007602 11 10 0,000 0,04278636 0,08291825 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,04278636 0,08283115 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,04278636 0,08274423 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,04278636 0,0826575 ! fat cell differentiation GO:0045444 10 10 0,000 0,04278636 0,08257095 ! myoblast differentiation GO:0045445 10 10 0,000 0,04278636 0,08248457 ! centrosome cycle GO:0007098 10 10 0,000 0,04278636 0,08239838 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,04278636 0,08231237 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,04278636 0,08222654 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,04278636 0,08214089 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,04278636 0,08205541 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,04278636 0,08197012 ! protein polyubiquitination GO:0000209 10 10 0,000 0,04278636 0,081885 ! glutamate metabolic process GO:0006536 11 10 0,000 0,04278636 0,08180006 ! plasma membrane organization GO:0007009 10 10 0,000 0,04278636 0,08171529 ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,04278636 0,0816307 ! lysosomal transport GO:0007041 10 10 0,000 0,04278636 0,08154628 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,04278636 0,08146204 GO:0030968|endoplasmic reticulum unfolded protein response, ! vesicle coating GO:0006901 10 10 0,000 0,04278636 0,08137797 ! exocrine system development GO:0035272 10 10 0,000 0,04278636 0,08129408 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,04278636 0,08121035 ! embryo implantation GO:0007566 11 10 0,000 0,04278636 0,0811268 ! regulation of protein binding GO:0043393 11 10 0,000 0,04278636 0,08104343 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,04278636 0,08096022 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,04278636 0,08087718 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,04278636 0,08079432 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,04278636 0,08071162 ! protein export from nucleus GO:0006611 10 10 0,000 0,04278636 0,08062909 ! negative regulation of immune response GO:0050777 10 10 0,000 0,04278636 0,08054673 ! cytolysis GO:0019835 10 10 0,000 0,04278636 0,08046454 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,04278636 0,08038252 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,04278636 0,08030067 ! histone deacetylation GO:0016575 10 10 0,000 0,04278636 0,08021898 ! mRNA splice site selection GO:0006376 11 10 0,000 0,04278636 0,08013745 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,04278636 0,08005609 ! gland morphogenesis GO:0022612 10 10 0,000 0,04278636 0,0799749 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,04278636 0,07989387 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,04278636 0,07981301 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,04278636 0,07973231 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,04278636 0,07965177 ! regulation of epidermis development GO:0045682 10 10 0,000 0,04278636 0,0795714 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,04278636 0,07949118 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,04278636 0,07941113 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,04278636 0,07933124 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,04278636 0,07925151 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,04278636 0,07917194 ! nerve development GO:0021675 10 10 0,000 0,04278636 0,07909253 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,04278636 0,07901328 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,04278636 0,07893419 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,04278636 0,07885525 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,04278636 0,07877648 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,04278636 0,07869786 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,04278636 0,0786194 ! protein stabilization GO:0050821 10 10 0,000 0,04278636 0,07854109 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,04292151 0,07871078 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,04394864 0,08051426 ! regulation of locomotion GO:0040012 79 79 1,000 0,04603051 0,08424453 ! nuclear transport GO:0051169 79 79 1,000 0,04603051 0,08416095 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 1,000 0,04603051 0,08407754 ! protein secretion GO:0009306 11 11 0,000 0,04696633 0,08570192 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04696633 0,08561715 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04696633 0,08553255 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04696633 0,08544812 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,04696633 0,08536385 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04696633 0,08527975 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04696633 0,08519581 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04696633 0,08511204 ! skin development GO:0043588 11 11 0,000 0,04696633 0,08502843 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04696633 0,08494499 ! microtubule-based transport GO:0010970 11 11 0,000 0,04696633 0,08486171 ! endothelial cell migration GO:0043542 11 11 0,000 0,04696633 0,08477859 ! peroxisomal transport GO:0043574 11 11 0,000 0,04696633 0,08469564 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04696633 0,08461285 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,04696633 0,08453022 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,04696633 0,08444775 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,04696633 0,08436544 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04696633 0,08428329 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04696633 0,08420131 ! T cell proliferation GO:0042098 11 11 0,000 0,04696633 0,08411948 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04696633 0,08403781 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04696633 0,0839563 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04696633 0,08387494 ! spinal cord development GO:0021510 11 11 0,000 0,04696633 0,08379375 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04696633 0,08371271 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,04696633 0,08363183 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04696633 0,0835511 ! digestive system process GO:0022600 11 11 0,000 0,04696633 0,08347053 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04696633 0,08339012 ! fucose metabolic process GO:0006004 11 11 0,000 0,04696633 0,08330986 ! membrane budding GO:0006900 11 11 0,000 0,04696633 0,08322975 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04696633 0,0831498 ! monoamine transport GO:0015844 11 11 0,000 0,04696633 0,08307 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04696633 0,08299036 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04696633 0,08291086 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,04696633 0,08283152 ! body fluid secretion GO:0007589 11 11 0,000 0,04696633 0,08275233 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,04696633 0,0826733 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04696633 0,08259441 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04696633 0,08251567 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04696633 0,08243709 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,04696633 0,08235865 ! membrane depolarization GO:0051899 11 11 0,000 0,04696633 0,08228036 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04696633 0,08220222 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,04696633 0,08212423 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04696633 0,08204639 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04696633 0,0819687 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,04696633 0,08189115 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,04696633 0,08181375 ! muscle maintenance GO:0046716 12 11 0,000 0,04696633 0,08173649 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04696633 0,08165938 ! hindbrain development GO:0030902 11 11 0,000 0,04696633 0,08158241 ! steroid catabolic process GO:0006706 11 11 0,000 0,04696633 0,0815056 ! endocrine process GO:0050886 11 11 0,000 0,04696633 0,08142892 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04696633 0,08135239 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04696633 0,081276 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04696633 0,08119976 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04696633 0,08112366 ! neuron projection development GO:0031175 85 80 1,000 0,04708506 0,08125259 ! tube development GO:0035295 83 81 1,000 0,04814856 0,08301011 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,05030205 0,08664176 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,05112865 0,08798329 ! translational initiation GO:0006413 12 12 0,000 0,05112865 0,08790122 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,05112865 0,0878193 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,05112865 0,08773753 ! initiation of viral infection GO:0019059 12 12 0,000 0,05112865 0,08765591 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,05112865 0,08757445 ! iron ion transport GO:0006826 13 12 0,000 0,05112865 0,08749314 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,05112865 0,08741197 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,05112865 0,08733096 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,05112865 0,0872501 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,05112865 0,08716939 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,05112865 0,08708882 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,05112865 0,08700841 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,05112865 0,08692814 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,05112865 0,08684803 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,05112865 0,08676805 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,05112865 0,08668823 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,05112865 0,08660855 ! actomyosin structure organization GO:0031032 12 12 0,000 0,05112865 0,08652902 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,05112865 0,08644964 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,05112865 0,0863704 ! retinoid metabolic process GO:0001523 12 12 0,000 0,05112865 0,08629131 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,05112865 0,08621236 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,05112865 0,08613355 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,05112865 0,08605489 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,05112865 0,08597638 ! acute-phase response GO:0006953 12 12 0,000 0,05112865 0,085898 ! vacuolar transport GO:0007034 12 12 0,000 0,05112865 0,08581977 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,05112865 0,08574168 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,05112865 0,08566373 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,05112865 0,08558593 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,05112865 0,08550826 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,05112865 0,08543074 ! male gonad development GO:0008584 12 12 0,000 0,05112865 0,08535336 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,05112865 0,08527612 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,05112865 0,08519901 ! renal system process GO:0003014 12 12 0,000 0,05112865 0,08512205 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,05112865 0,08504522 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,05112865 0,08496854 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,05112865 0,08489199 ! pallium development GO:0021543 13 12 0,000 0,05112865 0,08481558 ! cell fate determination GO:0001709 12 12 0,000 0,05112865 0,0847393 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,05112865 0,08466317 ! somitogenesis GO:0001756 13 12 0,000 0,05112865 0,08458717 ! G1 phase GO:0051318 13 12 0,000 0,05112865 0,08451131 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,05112865 0,08443558 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,05112865 0,08435999 ! detection of light stimulus GO:0009583 13 12 0,000 0,05112865 0,08428453 ! synaptogenesis GO:0007416 12 12 0,000 0,05112865 0,08420921 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,05112865 0,08413402 ! hormone transport GO:0009914 12 12 0,000 0,05112865 0,08405897 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,05112865 0,08398405 ! heme biosynthetic process GO:0006783 12 12 0,000 0,05112865 0,08390927 ! spermatid differentiation GO:0048515 13 12 0,000 0,05112865 0,08383461 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,05112865 0,0837601 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,05112865 0,08368571 ! neural tube closure GO:0001843 13 12 0,000 0,05112865 0,08361145 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,05112865 0,08353733 ! negative regulation of translation GO:0017148 12 12 0,000 0,05112865 0,08346334 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,05112865 0,08338948 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,05112865 0,08331574 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,05139186 0,08367066 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,05249025 0,08538351 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,05249025 0,08530822 ! heart development GO:0007507 90 87 1,000 0,05471242 0,08884141 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,0552734 0,08967331 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,0552734 0,08959444 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,0552734 0,08951571 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,0552734 0,08943712 ! phenol metabolic process GO:0018958 13 13 0,000 0,0552734 0,08935867 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,0552734 0,08928035 ! gluconeogenesis GO:0006094 13 13 0,000 0,0552734 0,08920217 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,0552734 0,08912413 ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,0552734 0,08904622 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,0552734 0,08896845 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,0552734 0,08889082 ! regeneration GO:0031099 13 13 0,000 0,0552734 0,08881332 ! keratinization GO:0031424 13 13 0,000 0,0552734 0,08873596 ! post-embryonic development GO:0009791 14 13 0,000 0,0552734 0,08865873 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,0552734 0,08858164 ! patterning of blood vessels GO:0001569 13 13 0,000 0,0552734 0,08850467 ! vasculogenesis GO:0001570 13 13 0,000 0,0552734 0,08842785 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,0552734 0,08835115 ! regulation of innate immune response GO:0045088 13 13 0,000 0,0552734 0,08827459 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,0552734 0,08819817 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,0552734 0,08812187 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,0552734 0,0880457 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,0552734 0,08796967 GO:0051384|response to glucocorticoid stimulus, ! autophagy GO:0006914 13 13 0,000 0,0552734 0,08789377 ! receptor metabolic process GO:0043112 14 13 0,000 0,0552734 0,087818 ! actin filament bundle formation GO:0051017 13 13 0,000 0,0552734 0,08774236 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,0552734 0,08766685 ! ureteric bud development GO:0001657 13 13 0,000 0,0552734 0,08759147 ! cell aging GO:0007569 13 13 0,000 0,0552734 0,08751622 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,0552734 0,0874411 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,0552734 0,08736611 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,0552734 0,08729124 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,0552734 0,08721651 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,0552734 0,0871419 ! regulation of peptide secretion GO:0002791 13 13 0,000 0,0552734 0,08706742 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,0552734 0,08699307 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,0552734 0,08691884 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,0552734 0,08684474 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,0552734 0,08677077 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,0552734 0,08669692 ! vasodilation GO:0042311 14 13 0,000 0,0552734 0,0866232 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,0552734 0,0865496 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,0552734 0,08647613 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,0552734 0,08640278 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,0552734 0,08632956 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,0552734 0,08625646 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,0552734 0,08618349 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,0552734 0,08611063 ! immunoglobulin production GO:0002377 13 13 0,000 0,0552734 0,08603791 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,0552734 0,0859653 ! cell-cell junction organization GO:0045216 13 13 0,000 0,0552734 0,08589282 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,0552734 0,08582046 GO:0001952|regulation of cell-matrix adhesion, ! response to cytokine stimulus GO:0034097 13 13 0,000 0,0552734 0,08574822 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,0552734 0,0856761 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,0552734 0,0856041 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,0552734 0,08553223 GO:0019370|leukotriene biosynthetic process, ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,0552734 0,08546047 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,0552734 0,08538884 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,0552734 0,08531732 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,0552734 0,08524593 ! telomere organization GO:0032200 13 13 0,000 0,0552734 0,08517465 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,0552734 0,08510349 ! regulation of amine transport GO:0051952 13 13 0,000 0,0552734 0,08503245 ! tissue homeostasis GO:0001894 13 13 0,000 0,0552734 0,08496154 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,0552734 0,08489073 ! DNA replication GO:0006260 91 91 1,000 0,0592559 0,0909314 ! neuron fate commitment GO:0048663 14 14 0,000 0,05940065 0,0910777 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,05940065 0,09100199 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,05940065 0,09092641 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,05940065 0,09085095 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,05940065 0,09077562 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,05940065 0,09070041 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,05940065 0,09062533 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,05940065 0,09055037 ! protein amino acid acylation GO:0043543 14 14 0,000 0,05940065 0,09047553 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,05940065 0,09040082 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,05940065 0,09032623 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,05940065 0,09025177 ! vesicle docking GO:0048278 14 14 0,000 0,05940065 0,09017743 ! superoxide metabolic process GO:0006801 15 14 0,000 0,05940065 0,09010321 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,05940065 0,09002911 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,05940065 0,08995513 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,05940065 0,08988128 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,05940065 0,08980754 ! hair cycle GO:0042633 14 14 0,000 0,05940065 0,08973393 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,05940065 0,08966044 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,05940065 0,08958707 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,05940065 0,08951381 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,05940065 0,08944068 ! lysosome organization GO:0007040 14 14 0,000 0,05940065 0,08936767 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,05940065 0,08929478 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,05940065 0,089222 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,05940065 0,08914934 ! primary neural tube formation GO:0014020 15 14 0,000 0,05940065 0,08907681 ! peptide cross-linking GO:0018149 14 14 0,000 0,05940065 0,08900439 ! regulation of behavior GO:0050795 14 14 0,000 0,05940065 0,08893208 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,05940065 0,0888599 ! base-excision repair GO:0006284 14 14 0,000 0,05940065 0,08878783 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,05940065 0,08871588 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,05940065 0,08864404 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,05940065 0,08857233 ! formation of primary germ layer GO:0001704 14 14 0,000 0,05940065 0,08850072 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,05940065 0,08842924 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,05940065 0,08835787 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,05940065 0,08828661 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,05940065 0,08821547 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,05940065 0,08814444 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,05940065 0,08807353 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,05940065 0,08800273 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,05940065 0,08793204 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,0604119 0,08935725 ! pattern specification process GO:0007389 96 94 1,000 0,06274748 0,09273745 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,06351046 0,09378989 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,06351046 0,0937148 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,06351046 0,09363983 ! positive regulation of ossification GO:0045778 15 15 0,000 0,06351046 0,09356497 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,06351046 0,09349024 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,06351046 0,09341563 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,06351046 0,09334113 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,06351046 0,09326676 ! response to vitamin GO:0033273 15 15 0,000 0,06351046 0,0931925 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,06351046 0,09311836 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,06351046 0,09304434 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,06351046 0,09297044 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,06351046 0,09289665 ! ovarian follicle development GO:0001541 15 15 0,000 0,06351046 0,09282298 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,06351046 0,09274943 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,06351046 0,09267599 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,06351046 0,09260268 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,06351046 0,09252947 ! heme metabolic process GO:0042168 15 15 0,000 0,06351046 0,09245638 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,06351046 0,09238341 ! chromosome condensation GO:0030261 15 15 0,000 0,06351046 0,09231055 ! response to ionizing radiation GO:0010212 16 15 0,000 0,06351046 0,09223781 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,06351046 0,09216518 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,06351046 0,09209267 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,06351046 0,09202027 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,06351046 0,09194798 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,06351046 0,09187581 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,06351046 0,09180375 ! phospholipid transport GO:0015914 15 15 0,000 0,06351046 0,0917318 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,06351046 0,09165997 ! glutathione metabolic process GO:0006749 16 15 0,000 0,06351046 0,09158825 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,06351046 0,09151664 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,06351046 0,09144514 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,06351046 0,09137376 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,06351046 0,09130248 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,06351046 0,09123132 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,06351046 0,09116027 ! regulation of cell growth GO:0001558 97 96 1,000 0,0651139 0,09338904 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,06760291 0,09688349 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,06760291 0,09680821 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,06760291 0,09673305 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,06760291 0,09665801 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,06760291 0,09658308 ! learning GO:0007612 16 16 0,000 0,06760291 0,09650827 ! circadian rhythm GO:0007623 16 16 0,000 0,06760291 0,09643357 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,06760291 0,09635899 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,06760291 0,09628452 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,06760291 0,09621017 ! vacuole organization GO:0007033 16 16 0,000 0,06760291 0,09613593 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,06760291 0,09606181 ! vesicle targeting GO:0006903 17 16 0,000 0,06760291 0,09598781 ! segmentation GO:0035282 17 16 0,000 0,06760291 0,09591391 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,06760291 0,09584013 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,06760291 0,09576647 ! iron ion homeostasis GO:0055072 16 16 0,000 0,06760291 0,09569291 ! positive regulation of cell development GO:0010720 16 16 0,000 0,06760291 0,09561947 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,06760291 0,09554614 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,06760291 0,09547293 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,06760291 0,09539982 ! cell fate specification GO:0001708 16 16 0,000 0,06760291 0,09532683 ! fatty acid transport GO:0015908 16 16 0,000 0,06760291 0,09525395 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,06760291 0,09518119 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,06760291 0,09510853 ! cofactor catabolic process GO:0051187 16 16 0,000 0,06760291 0,09503598 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,06760291 0,09496355 ! polyol metabolic process GO:0019751 16 16 0,000 0,06760291 0,09489122 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,06760291 0,094819 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,06760291 0,0947469 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,06760291 0,0946749 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,06760291 0,09460302 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,06760291 0,09453124 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,06760291 0,09445957 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,06760291 0,09438801 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,06760291 0,09431656 ! muscle organ development GO:0007517 102 100 1,000 0,06993662 0,09749863 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,06993662 0,09742493 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,07167808 0,09977545 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,07167808 0,09970015 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,07167808 0,09962496 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,07167808 0,09954988 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,07167808 0,09947492 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,07167808 0,09940007 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,07167808 0,09932533 ! leukocyte adhesion GO:0007159 17 17 0,000 0,07167808 0,09925071 ! sensory perception of smell GO:0007608 17 17 0,000 0,07167808 0,0991762 ! glucose transport GO:0015758 17 17 0,000 0,07167808 0,0991018 ! cell junction assembly GO:0034329 18 17 0,000 0,07167808 0,09902751 ! tissue remodeling GO:0048771 17 17 0,000 0,07167808 0,09895333 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,07167808 0,09887926 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,07167808 0,09880531 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,07167808 0,09873146 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,07167808 0,09865773 ! neural crest cell development GO:0014032 19 17 0,000 0,07167808 0,0985841 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,07167808 0,09851059 ! negative regulation of cell development GO:0010721 18 17 0,000 0,07167808 0,09843718 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,07167808 0,09836388 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,07167808 0,0982907 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,07167808 0,09821762 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,07167808 0,09814465 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,07167808 0,09807179 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,07167808 0,09799903 ! pigmentation GO:0043473 17 17 0,000 0,07167808 0,09792639 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,07167808 0,09785385 ! adult locomotory behavior GO:0008344 17 17 0,000 0,07167808 0,09778142 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,07167808 0,09770909 ! gene silencing GO:0016458 17 17 0,000 0,07167808 0,09763688 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,07573602 0,10308824 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,07573602 0,10301216 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,07573602 0,1029362 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,07573602 0,10286034 ! meiosis I GO:0007127 18 18 0,000 0,07573602 0,1027846 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,07573602 0,10270896 ! membrane docking GO:0022406 18 18 0,000 0,07573602 0,10263344 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,07573602 0,10255803 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,07573602 0,10248273 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,07573602 0,10240754 ! hexose transport GO:0008645 18 18 0,000 0,07573602 0,10233247 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,07573602 0,1022575 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,07573602 0,10218264 ! striated muscle contraction GO:0006941 18 18 0,000 0,07573602 0,10210789 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,07573602 0,10203325 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,07573602 0,10195872 ! ceramide metabolic process GO:0006672 18 18 0,000 0,07573602 0,10188429 GO:0046519|sphingoid metabolic process, ! telencephalon development GO:0021537 19 18 0,000 0,07573602 0,10180998 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,07573602 0,10173577 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,07573602 0,10166168 ! B cell differentiation GO:0030183 18 18 0,000 0,07573602 0,10158769 ! BMP signaling pathway GO:0030509 18 18 0,000 0,07573602 0,10151381 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,07573602 0,10144003 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,07573602 0,10136636 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,07573602 0,1012928 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,07573602 0,10121935 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,07977681 0,10654251 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,07977681 0,10646536 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,07977681 0,10638832 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,07977681 0,1063114 ! glial cell differentiation GO:0010001 19 19 0,000 0,07977681 0,10623458 ! regulation of pH GO:0006885 19 19 0,000 0,07977681 0,10615788 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,07977681 0,10608129 ! feeding behavior GO:0007631 19 19 0,000 0,07977681 0,1060048 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,07977681 0,10592843 ! peroxisome organization GO:0007031 19 19 0,000 0,07977681 0,10585217 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,07977681 0,10577602 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,07977681 0,10569997 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,07977681 0,10562404 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,07977681 0,10554822 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,07977681 0,1054725 ! regulation of protein stability GO:0031647 19 19 0,000 0,07977681 0,10539689 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,07977681 0,10532139 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,07977681 0,105246 ! eye morphogenesis GO:0048592 19 19 0,000 0,07977681 0,10517072 ! regulation of cell shape GO:0008360 21 19 0,000 0,07977681 0,10509554 ! vesicle localization GO:0051648 20 19 0,000 0,07977681 0,10502047 ! regulation of muscle development GO:0048634 21 20 0,000 0,08380052 0,11023866 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,08380052 0,11016003 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,08380052 0,11008152 ! negative regulation of binding GO:0051100 21 20 0,000 0,08380052 0,11000311 ! organic ether metabolic process GO:0018904 20 20 0,000 0,08380052 0,10992482 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,08380052 0,10984663 ! neural tube development GO:0021915 21 20 0,000 0,08380052 0,10976856 ! nucleus organization GO:0006997 20 20 0,000 0,08380052 0,1096906 ! phagocytosis GO:0006909 21 20 0,000 0,08380052 0,10961275 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,08380052 0,10953501 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,08380052 0,10945738 ! protein targeting to membrane GO:0006612 22 20 0,000 0,08380052 0,10937986 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,08380052 0,10930245 ! chromatin remodeling GO:0006338 20 20 0,000 0,08380052 0,10922515 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,08380052 0,10914796 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,08380052 0,10907088 ! lipid oxidation GO:0034440 20 20 0,000 0,08380052 0,10899391 GO:0019395|fatty acid oxidation, ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,08380052 0,10891704 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,08380052 0,10884029 ! RNA modification GO:0009451 20 20 0,000 0,08380052 0,10876364 ! single fertilization GO:0007338 21 20 0,000 0,08380052 0,1086871 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,08780723 0,1138036 ! mRNA catabolic process GO:0006402 21 21 0,000 0,08780723 0,11372363 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,08780723 0,11364376 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,08780723 0,11356401 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,08780723 0,11348438 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,08780723 0,11340485 ! Notch signaling pathway GO:0007219 22 21 0,000 0,08780723 0,11332543 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,08780723 0,11324613 ! organic anion transport GO:0015711 21 21 0,000 0,08780723 0,11316694 ! cholesterol transport GO:0030301 21 21 0,000 0,08780723 0,11308786 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,08780723 0,11300888 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,08780723 0,11293002 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,08780723 0,11285127 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,08780723 0,11277263 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,08780723 0,1126941 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,08780723 0,11261567 ! regulation of proteolysis GO:0030162 21 21 0,000 0,08780723 0,11253736 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,08780723 0,11245915 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,08780723 0,11238106 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,08780723 0,11230307 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,09179699 0,11732445 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,09179699 0,11724314 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,09179699 0,11716195 ! sister chromatid segregation GO:0000819 22 22 0,000 0,09179699 0,11708087 ! regulation of ion transport GO:0043269 22 22 0,000 0,09179699 0,1169999 ! odontogenesis GO:0042476 22 22 0,000 0,09179699 0,11691904 ! cell junction organization GO:0034330 23 22 0,000 0,09179699 0,1168383 ! hormone-mediated signaling GO:0009755 22 22 0,000 0,09179699 0,11675766 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,09179699 0,11667714 ! spindle organization GO:0007051 22 22 0,000 0,09179699 0,11659673 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,09179699 0,11651643 ! cell chemotaxis GO:0060326 23 22 0,000 0,09179699 0,11643624 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,09179699 0,11635616 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,09179699 0,11627619 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,09179699 0,11619633 ! biopolymer methylation GO:0043414 22 22 0,000 0,09179699 0,11611658 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,09179699 0,11603694 ! detection of external stimulus GO:0009581 23 22 0,000 0,09179699 0,1159574 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,09179699 0,11587798 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,09179699 0,11579867 ! aerobic respiration GO:0009060 22 22 0,000 0,09179699 0,11571946 ! cytokine production GO:0001816 22 22 0,000 0,09179699 0,11564036 ! cytokinesis GO:0000910 23 22 0,000 0,09179699 0,11556138 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,09576988 0,12048047 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,09576988 0,12039829 ! viral infectious cycle GO:0019058 23 23 0,000 0,09576988 0,12031622 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,09576988 0,12023426 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,09576988 0,12015241 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,09576988 0,12007068 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,09576988 0,11998905 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,09576988 0,11990754 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,09576988 0,11982613 ! endocrine system development GO:0035270 23 23 0,000 0,09576988 0,11974484 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,09576988 0,11966366 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,09576988 0,11958258 ! lipid homeostasis GO:0055088 23 23 0,000 0,09576988 0,11950162 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,09576988 0,11942077 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,09576988 0,11934002 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,09576988 0,11925939 ! mitochondrial transport GO:0006839 24 24 0,000 0,09972597 0,12410193 ! gliogenesis GO:0042063 24 24 0,000 0,09972597 0,1240182 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,09972597 0,12393457 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,09972597 0,12385105 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,09972597 0,12376765 ! T cell differentiation GO:0030217 24 24 0,000 0,09972597 0,12368436 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,09972597 0,12360119 ! fertilization GO:0009566 25 24 0,000 0,09972597 0,12351812 ! maintenance of protein location GO:0045185 25 24 0,000 0,09972597 0,12343517 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,09972597 0,12335233 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,09972597 0,12326959 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,09972597 0,12318697 ! glucan metabolic process GO:0044042 25 24 0,000 0,09972597 0,12310446 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! negative regulation of secretion GO:0051048 26 25 0,000 0,10366533 0,12788166 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,10366533 0,12779612 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,10366533 0,12771069 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,10366533 0,12762538 ! cellular component disassembly GO:0022411 26 25 0,000 0,10366533 0,12754019 ! endosome transport GO:0016197 25 25 0,000 0,10366533 0,1274551 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,10366533 0,12737013 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,10366533 0,12728527 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,10366533 0,12720053 ! excretion GO:0007588 25 25 0,000 0,10366533 0,1271159 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,10366533 0,12703138 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,10366533 0,12694698 ! gastrulation GO:0007369 25 25 0,000 0,10366533 0,12686268 ! heart morphogenesis GO:0003007 25 25 0,000 0,10366533 0,1267785 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,10366533 0,12669443 ! regulation of endocytosis GO:0030100 25 25 0,000 0,10366533 0,12661047 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,10366533 0,12652662 ! positive regulation of binding GO:0051099 27 26 0,000 0,10758802 0,13122748 ! glycolysis GO:0006096 26 26 0,000 0,10758802 0,13114068 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,10758802 0,13105401 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,10758802 0,13096745 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,10758802 0,130881 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,10758802 0,13079467 ! cellular defense response GO:0006968 26 26 0,000 0,10758802 0,13070845 ! double-strand break repair GO:0006302 27 26 0,000 0,10758802 0,13062234 ! regulation of protein secretion GO:0050708 26 26 0,000 0,10758802 0,13053635 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,10758802 0,13045047 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,10758802 0,1303647 ! maintenance of location in cell GO:0051651 27 26 0,000 0,10758802 0,13027905 ! chloride transport GO:0006821 27 27 0,000 0,11149411 0,13492032 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,11149411 0,13483179 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,11149411 0,13474337 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,11149411 0,13465507 ! learning or memory GO:0007611 28 27 0,000 0,11149411 0,13456689 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,11149411 0,13447882 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,11149411 0,13439087 ! peptide metabolic process GO:0006518 29 27 0,000 0,11149411 0,13430304 ! activation of caspase activity GO:0006919 27 27 0,000 0,11149411 0,13421531 ! mesenchymal cell development GO:0014031 29 27 0,000 0,11149411 0,1341277 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,11149411 0,13404021 ! defense response to bacterium GO:0042742 27 27 0,000 0,11149411 0,13395283 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,11149411 0,13386557 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,11149411 0,13377841 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,11538367 0,13835531 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,11538367 0,13826535 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,11538367 0,13817551 ! carbohydrate transport GO:0008643 28 28 0,000 0,11538367 0,13808579 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,11538367 0,13799618 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,11538367 0,13790669 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,11538367 0,13781731 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,11538367 0,13772805 ! histone modification GO:0016570 28 28 0,000 0,11538367 0,13763891 ! cartilage development GO:0051216 29 28 0,000 0,11538367 0,13754988 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,11925677 0,14207514 ! viral reproductive process GO:0022415 29 29 0,000 0,11925677 0,14198336 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,11925677 0,14189169 ! leukocyte migration GO:0050900 30 29 0,000 0,11925677 0,14180015 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,11925677 0,14170873 ! antigen processing and presentation GO:0019882 29 29 0,000 0,11925677 0,14161742 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,11925677 0,14152623 ! tRNA processing GO:0008033 29 29 0,000 0,11925677 0,14143516 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,11925677 0,1413442 ! covalent chromatin modification GO:0016569 29 29 0,000 0,11925677 0,14125336 ! adult behavior GO:0030534 30 29 0,000 0,11925677 0,14116264 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,11925677 0,14107204 ! response to UV GO:0009411 29 29 0,000 0,11925677 0,14098155 ! transition metal ion transport GO:0000041 31 30 0,000 0,12311348 0,14544753 ! RNA catabolic process GO:0006401 30 30 0,000 0,12311348 0,14535435 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,12311348 0,1452613 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,12311348 0,14516836 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,12311348 0,14507554 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,12311348 0,14498284 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,12311348 0,14489026 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,12311348 0,1447978 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,12311348 0,14470545 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,12311348 0,14461322 ! regulation of ossification GO:0030278 30 30 0,000 0,12311348 0,14452111 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,12311348 0,14442912 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,12311348 0,14433724 GO:0019724|B cell mediated immunity, ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,12311348 0,14424548 ! vesicle organization GO:0016050 30 30 0,000 0,12311348 0,14415384 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,12311348 0,14406231 ! establishment of organelle localization GO:0051656 31 30 0,000 0,12311348 0,1439709 ! membrane fusion GO:0006944 31 31 0,000 0,12695386 0,14836776 ! B cell activation GO:0042113 31 31 0,000 0,12695386 0,14827374 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,12695386 0,14817984 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,12695386 0,14808605 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,12695386 0,14799239 ! ion transmembrane transport GO:0034220 31 31 0,000 0,12695386 0,14789884 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,12695386 0,14780541 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,12695386 0,1477121 ! digestion GO:0007586 31 31 0,000 0,12695386 0,1476189 ! regulation of DNA replication GO:0006275 32 31 0,000 0,12695386 0,14752583 ! regulation of heart contraction GO:0008016 31 31 0,000 0,12695386 0,14743287 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,12695386 0,14734003 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,12695386 0,1472473 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,12695386 0,14715469 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,12695386 0,1470622 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,12695386 0,14696983 ! cell redox homeostasis GO:0045454 32 32 0,000 0,13077798 0,15130183 ! glucose catabolic process GO:0006007 32 32 0,000 0,13077798 0,15120691 ! lipid modification GO:0030258 32 32 0,000 0,13077798 0,15111211 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,13077798 0,15101743 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,13077798 0,15092286 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,13077798 0,15082842 ! cell maturation GO:0048469 32 32 0,000 0,13077798 0,15073409 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,13077798 0,15063988 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,13077798 0,15054579 ! nuclear export GO:0051168 32 32 0,000 0,13077798 0,15045182 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,13077798 0,15035796 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,13077798 0,15026422 ! maintenance of location GO:0051235 33 32 0,000 0,13077798 0,1501706 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,1345859 0,15444696 ! amino acid transport GO:0006865 33 33 0,000 0,1345859 0,15435085 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,1345859 0,15425486 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,1345859 0,15415899 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,1345859 0,15406324 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,1345859 0,15396761 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,1383777 0,15820725 ! response to metal ion GO:0010038 34 34 0,000 0,1383777 0,15810917 ! muscle cell differentiation GO:0042692 35 34 0,000 0,1383777 0,15801121 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,1383777 0,15791337 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,1383777 0,15781565 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,1383777 0,15771805 ! secondary metabolic process GO:0019748 34 34 0,000 0,1383777 0,15762058 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,1383777 0,15752322 ! viral reproduction GO:0016032 34 34 0,000 0,1383777 0,15742598 ! detection of stimulus GO:0051606 36 34 0,000 0,1383777 0,15732887 ! acute inflammatory response GO:0002526 35 35 0,000 0,14215343 0,16152205 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,14215343 0,16142253 ! mesoderm development GO:0007498 35 35 0,000 0,14215343 0,16132313 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,14215343 0,16122386 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,14215343 0,16112471 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,14215343 0,16102567 ! inorganic anion transport GO:0015698 35 35 0,000 0,14215343 0,16092676 ! regulation of immune effector process GO:0002697 35 35 0,000 0,14215343 0,16082797 ! hydrogen transport GO:0006818 36 36 0,000 0,14591317 0,16498035 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,14591317 0,16487919 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,14591317 0,16477817 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,14591317 0,16467726 ! regulation of mitosis GO:0007088 37 36 0,000 0,14591317 0,16457648 GO:0051783|regulation of nuclear division, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,14591317 0,16447582 GO:0045937|positive regulation of phosphate metabolic process, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,14591317 0,16437528 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,14591317 0,16427487 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,14591317 0,16417458 ! regulation of lipase activity GO:0060191 36 36 0,000 0,14591317 0,16407441 ! activation of immune response GO:0002253 36 36 0,000 0,14591317 0,16397437 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,14965697 0,1680791 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,14965697 0,16797674 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,14965697 0,1678745 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 0,000 0,14965697 0,16777238 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,14965697 0,16767039 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,14965697 0,16756853 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,14965697 0,16746679 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,14965697 0,16736517 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,14965697 0,16726367 ! adaptive immune response GO:0002250 37 37 0,000 0,14965697 0,1671623 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,15338491 0,17122253 ! neurotransmitter transport GO:0006836 40 38 0,000 0,15338491 0,17111888 ! exocytosis GO:0006887 40 38 0,000 0,15338491 0,17101536 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,15338491 0,17091197 ! chromosome segregation GO:0007059 38 38 0,000 0,15338491 0,1708087 ! hexose catabolic process GO:0019320 38 38 0,000 0,15338491 0,17070555 ! RNA elongation GO:0006354 38 38 0,000 0,15338491 0,17060253 ! meiotic cell cycle GO:0051321 38 38 0,000 0,15338491 0,17049963 ! regulation of neurological system process GO:0031644 38 38 0,000 0,15338491 0,17039686 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,15709705 0,17441558 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,15709705 0,17431057 ! activation of MAPK activity GO:0000187 39 39 0,000 0,15709705 0,17420569 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,15709705 0,17410094 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,15709705 0,17399631 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,15709705 0,17389181 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,15709705 0,17378743 ! developmental maturation GO:0021700 39 39 0,000 0,15709705 0,17368318 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,16079345 0,17766327 ! DNA catabolic process GO:0006308 41 40 0,000 0,16079345 0,17755682 ! organelle localization GO:0051640 41 40 0,000 0,16079345 0,1774505 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,16447418 0,1814039 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,16447418 0,18129541 ! amine catabolic process GO:0009310 42 41 0,000 0,16447418 0,18118704 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,16447418 0,1810788 ! regulation of caspase activity GO:0043281 41 41 0,000 0,16447418 0,1809707 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,16447418 0,18086272 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,16447418 0,18075487 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,16447418 0,18064715 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,16447418 0,18053956 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,16813931 0,18445282 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,16813931 0,18434309 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,16813931 0,1842335 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,16813931 0,18412403 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,16813931 0,18401469 ! protein ubiquitination GO:0016567 43 42 0,000 0,16813931 0,18390548 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,16813931 0,18379641 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 0,000 0,16813931 0,18368746 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,16813931 0,18357864 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,16813931 0,18346995 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,17178888 0,18734137 ! mitochondrion organization GO:0007005 44 43 0,000 0,17178888 0,18723058 ! alcohol catabolic process GO:0046164 43 43 0,000 0,17178888 0,18711993 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,17178888 0,1870094 ! humoral immune response GO:0006959 44 44 0,000 0,17542298 0,19085275 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,17542298 0,19074015 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,17542298 0,19062769 ! vitamin metabolic process GO:0006766 44 44 0,000 0,17542298 0,19051536 ! amine biosynthetic process GO:0009309 46 45 0,000 0,17904167 0,19433085 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,17904167 0,19421647 ! regulation of DNA binding GO:0051101 47 45 0,000 0,17904167 0,19410223 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,17904167 0,19398812 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,17904167 0,19387414 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,17904167 0,1937603 ! protein processing GO:0016485 45 45 0,000 0,17904167 0,19364659 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,18264499 0,19742799 ! tube morphogenesis GO:0035239 47 46 0,000 0,18264499 0,19731226 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,18264499 0,19719667 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,18264499 0,19708122 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,18264499 0,1969659 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,18264499 0,19685072 ! regulation of blood pressure GO:0008217 48 47 0,000 0,18623303 0,20060051 ! amine transport GO:0015837 47 47 0,000 0,18623303 0,20048334 ! regulation of catabolic process GO:0009894 48 47 0,000 0,18623303 0,2003663 ! calcium ion transport GO:0006816 48 48 0,000 0,18980584 0,20409111 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,18980584 0,20397211 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,18980584 0,20385324 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,18980584 0,20373452 ! DNA recombination GO:0006310 48 48 0,000 0,18980584 0,20361593 ! ossification GO:0001503 50 49 0,000 0,19336349 0,20731175 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 0,000 0,19336349 0,20719122 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,19336349 0,20707083 ! divalent metal ion transport GO:0070838 49 49 0,000 0,19336349 0,20695058 ! response to nutrient GO:0007584 49 49 0,000 0,19336349 0,20683047 ! response to bacterium GO:0009617 50 49 0,000 0,19336349 0,2067105 ! regulation of ligase activity GO:0051340 50 49 0,000 0,19336349 0,20659067 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,19336349 0,20647098 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,19690603 0,21013191 ! negative regulation of transport GO:0051051 51 50 0,000 0,19690603 0,2100103 ! chromatin assembly GO:0031497 50 50 0,000 0,19690603 0,20988884 GO:0006334|nucleosome assembly, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,19690603 0,20976752 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,19690603 0,20964634 ! transcription initiation GO:0006352 50 50 0,000 0,19690603 0,20952529 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,19690603 0,20940439 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,19690603 0,20928363 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,20043353 0,21291008 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,20043353 0,21278744 ! positive regulation of immune response GO:0050778 51 51 0,000 0,20043353 0,21266493 ! rRNA metabolic process GO:0016072 51 51 0,000 0,20043353 0,21254257 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,20043353 0,21242035 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,20043353 0,21229827 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,20043353 0,21217633 ! protein maturation GO:0051604 51 51 0,000 0,20043353 0,21205453 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,20394604 0,21564691 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,20394604 0,21552326 ! cell fate commitment GO:0045165 52 52 0,000 0,20394604 0,21539975 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,20394604 0,21527638 ! response to light stimulus GO:0009416 53 52 0,000 0,20394604 0,21515315 ! sodium ion transport GO:0006814 53 53 0,000 0,20744365 0,21871776 ! tRNA metabolic process GO:0006399 53 53 0,000 0,20744365 0,2185927 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,20744365 0,21846779 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,20744365 0,21834303 ! regulation of protein transport GO:0051223 53 53 0,000 0,20744365 0,2182184 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,21092639 0,22175547 ! response to virus GO:0009615 54 54 0,000 0,21092639 0,22162904 ! nucleosome organization GO:0034728 55 55 0,000 0,21439434 0,22514459 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,21439434 0,22501638 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,21439434 0,22488831 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,21439434 0,22476039 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,21784755 0,22825073 ! regulation of nervous system development GO:0051960 57 56 0,000 0,21784755 0,22812104 ! regulation of binding GO:0051098 60 57 0,000 0,22128608 0,23159015 ! ATP metabolic process GO:0046034 57 57 0,000 0,22128608 0,23145871 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,22128608 0,23132743 ! regulation of protein localization GO:0032880 58 57 0,000 0,22128608 0,23119629 ! innate immune response GO:0045087 58 58 0,000 0,22471001 0,23464053 ! dephosphorylation GO:0016311 60 59 0,000 0,22811937 0,23806569 ! carboxylic acid transport GO:0046942 59 59 0,000 0,22811937 0,23793096 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,22811937 0,23779638 ! regulation of cell development GO:0060284 60 59 0,000 0,22811937 0,23766196 ! sterol metabolic process GO:0016125 59 59 0,000 0,22811937 0,23752769 ! immune effector process GO:0002252 59 59 0,000 0,22811937 0,23739357 ! potassium ion transport GO:0006813 60 60 0,000 0,23151424 0,24079049 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,23151424 0,24065468 ! protein polymerization GO:0051258 65 60 0,000 0,23151424 0,24051903 ! cellular respiration GO:0045333 62 61 0,000 0,23489468 0,24389346 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,23489468 0,24375614 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,23489468 0,24361896 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,23489468 0,24348194 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,23826074 0,24683223 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,23826074 0,24669356 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,23826074 0,24655505 GO:0060429|epithelium development, ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,23826074 0,24641669 ! regulation of secretion GO:0051046 65 63 0,000 0,24161248 0,24974302 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,24161248 0,24960303 ! glucose metabolic process GO:0006006 63 63 0,000 0,24161248 0,2494632 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,24161248 0,24932352 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,24494997 0,25262607 ! angiogenesis GO:0001525 65 64 0,000 0,24494997 0,25248478 ! anion transport GO:0006820 65 65 0,000 0,24827325 0,25576724 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,25158239 0,25903148 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! DNA packaging GO:0006323 66 66 0,000 0,25158239 0,25888685 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,25158239 0,25874238 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,25158239 0,25859807 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,25487745 0,26183899 ! muscle contraction GO:0006936 67 67 0,000 0,25487745 0,26169311 ! response to radiation GO:0009314 70 68 0,000 0,25815848 0,2649143 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,25815848 0,26476688 ! sensory perception of sound GO:0007605 71 69 0,000 0,26142555 0,26796846 GO:0050954|sensory perception of mechanical stimulus, ! positive regulation of transport GO:0051050 71 70 0,000 0,2646787 0,27115222 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,2646787 0,27100158 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,267918 0,27416595 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,267918 0,27401381 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,267918 0,27386183 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,267918 0,27371002 ! secretion by cell GO:0032940 75 72 0,000 0,27114351 0,27685179 ! muscle system process GO:0003012 72 72 0,000 0,27114351 0,2766985 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,27114351 0,27654537 ! electron transport chain GO:0022900 75 74 0,000 0,27755335 0,28292634 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,27755335 0,28276994 ! response to oxidative stress GO:0006979 76 75 0,000 0,28073781 0,28585623 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,28706606 0,29213846 ! regulation of protein modification process GO:0031399 79 78 0,000 0,29020997 0,29517493 ! microtubule-based movement GO:0007018 82 78 0,000 0,29020997 0,29501212 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,29020997 0,29484949 ! metal ion homeostasis GO:0055065 78 78 0,000 0,29020997 0,29468704 ! regulation of immune response GO:0050776 78 78 0,000 0,29020997 0,29452477 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,29645763 0,30069974 ! lipid catabolic process GO:0016042 82 81 0,000 0,2995615 0,30368088 ! ncRNA processing GO:0034470 83 83 0,000 0,30572956 0,30976338 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,30572956 0,30959318 ! regulation of cellular localization GO:0060341 86 85 0,000 0,31184511 0,31561259 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,31488332 0,3185126 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,31488332 0,31833788 ! male gamete generation GO:0048232 90 88 0,000 0,32092089 0,32426381 GO:0007283|spermatogenesis, ! chemotaxis GO:0006935 90 89 0,000 0,32392035 0,32711518 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,32392035 0,32693604 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,32690701 0,32976991 ! brain development GO:0007420 91 90 0,000 0,32690701 0,32958951 ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,32988091 0,33240597 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,32988091 0,33222433 ! visual perception GO:0007601 93 92 0,000 0,33284211 0,33502349 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,33284211 0,33484062 ! tissue morphogenesis GO:0048729 94 93 0,000 0,33579066 0,33762258 ! blood vessel development GO:0001568 95 94 0,000 0,33872661 0,34038884 ! epidermis development GO:0008544 94 94 0,000 0,33872661 0,34020334 ! cofactor metabolic process GO:0051186 95 94 0,000 0,33872661 0,34001805 ! vasculature development GO:0001944 97 96 0,000 0,34456091 0,34568632 ! endocytosis GO:0006897 99 98 0,000 0,35034545 0,35129851 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,35034545 0,35110748 ! blood circulation GO:0008015 99 98 0,000 0,35034545 0,35091666 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,35034545 0,35072605 ! ectoderm development GO:0007398 99 99 0,000 0,35321918 0,35341094 ! response to other organism GO:0051707 101 100 0,000 0,35608062 0,35608062